K08M4_RS15455 505d705463f46b2a2bc967ca2bb7f110 187 Gene3D G3DSA:2.160.10.10 2 184 5.4E-61 T 05-07-2017 K08M4_RS15455 505d705463f46b2a2bc967ca2bb7f110 187 SMART SM01266 5 58 6.9E-14 T 05-07-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 K08M4_RS15455 505d705463f46b2a2bc967ca2bb7f110 187 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 131 164 2.7E-9 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS15455 505d705463f46b2a2bc967ca2bb7f110 187 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 93 105 0.033 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS15455 505d705463f46b2a2bc967ca2bb7f110 187 Pfam PF12464 Maltose acetyltransferase 7 54 5.6E-11 T 05-07-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 K08M4_RS15455 505d705463f46b2a2bc967ca2bb7f110 187 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 138 166 - T 05-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 K08M4_RS15455 505d705463f46b2a2bc967ca2bb7f110 187 SUPERFAMILY SSF51161 2 184 1.94E-50 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS08610 b1eca9ae5a3ea777555807882d5f9ec0 165 Pfam PF00072 Response regulator receiver domain 6 125 4.8E-14 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS08610 b1eca9ae5a3ea777555807882d5f9ec0 165 Gene3D G3DSA:3.40.50.2300 6 132 2.8E-20 T 05-07-2017 K08M4_RS08610 b1eca9ae5a3ea777555807882d5f9ec0 165 SUPERFAMILY SSF52172 1 136 5.55E-21 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS08610 b1eca9ae5a3ea777555807882d5f9ec0 165 SMART SM00448 4 125 2.3E-14 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 SUPERFAMILY SSF50249 255 363 3.43E-28 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 Gene3D G3DSA:2.40.50.140 102 172 3.0E-13 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 SUPERFAMILY SSF50249 190 277 1.79E-26 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 SUPERFAMILY SSF50249 429 538 2.09E-21 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 SUPERFAMILY SSF50249 104 184 4.32E-13 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 SUPERFAMILY SSF50249 3 112 4.72E-17 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 SUPERFAMILY SSF50249 342 440 1.34E-21 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 Gene3D G3DSA:2.40.50.140 192 274 8.8E-30 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 Gene3D G3DSA:2.40.50.140 21 101 1.1E-10 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 Gene3D G3DSA:2.40.50.140 453 537 3.2E-19 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 SMART SM00316 103 171 1.2E-7 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 SMART SM00316 449 520 2.6E-18 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 SMART SM00316 190 260 9.7E-28 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 SMART SM00316 362 434 2.8E-21 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 SMART SM00316 275 347 8.3E-27 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 SMART SM00316 19 87 6.1E-4 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 PRINTS PR00681 Ribosomal protein S1 signature 155 175 6.0E-97 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 PRINTS PR00681 Ribosomal protein S1 signature 108 124 6.0E-97 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 PRINTS PR00681 Ribosomal protein S1 signature 330 348 6.0E-97 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 PRINTS PR00681 Ribosomal protein S1 signature 126 143 6.0E-97 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 PRINTS PR00681 Ribosomal protein S1 signature 84 103 6.0E-97 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 PRINTS PR00681 Ribosomal protein S1 signature 212 233 6.0E-97 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 PRINTS PR00681 Ribosomal protein S1 signature 290 309 6.0E-97 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 PRINTS PR00681 Ribosomal protein S1 signature 39 53 6.0E-97 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 PRINTS PR00681 Ribosomal protein S1 signature 21 39 6.0E-97 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 Gene3D G3DSA:2.40.50.140 360 442 1.1E-24 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 Gene3D G3DSA:2.40.50.140 275 358 6.9E-30 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 Pfam PF00575 S1 RNA binding domain 449 520 3.8E-14 T 05-07-2017 IPR003029 S1 domain GO:0003676 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 Pfam PF00575 S1 RNA binding domain 362 434 1.6E-20 T 05-07-2017 IPR003029 S1 domain GO:0003676 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 Pfam PF00575 S1 RNA binding domain 18 86 4.1E-6 T 05-07-2017 IPR003029 S1 domain GO:0003676 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 Pfam PF00575 S1 RNA binding domain 275 347 7.7E-21 T 05-07-2017 IPR003029 S1 domain GO:0003676 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 Pfam PF00575 S1 RNA binding domain 104 171 7.6E-8 T 05-07-2017 IPR003029 S1 domain GO:0003676 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 Pfam PF00575 S1 RNA binding domain 189 260 3.2E-21 T 05-07-2017 IPR003029 S1 domain GO:0003676 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 PIRSF PIRSF002111 1 534 9.7E-217 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 K08M4_RS09780 a677a8fae0739ddb6bef6cdaee9fca04 556 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 520 7.3E-230 T 05-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 K08M4_RS08580 1ba7b76c51e40cd9dd3419c7fddfe2c7 629 Gene3D G3DSA:2.60.120.10 10 137 6.4E-24 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS08580 1ba7b76c51e40cd9dd3419c7fddfe2c7 629 Pfam PF00571 CBS domain 226 278 2.1E-10 T 05-07-2017 IPR000644 CBS domain K08M4_RS08580 1ba7b76c51e40cd9dd3419c7fddfe2c7 629 Pfam PF00571 CBS domain 152 214 1.4E-5 T 05-07-2017 IPR000644 CBS domain K08M4_RS08580 1ba7b76c51e40cd9dd3419c7fddfe2c7 629 SMART SM00116 159 216 0.47 T 05-07-2017 IPR000644 CBS domain K08M4_RS08580 1ba7b76c51e40cd9dd3419c7fddfe2c7 629 SMART SM00116 233 280 4.3E-6 T 05-07-2017 IPR000644 CBS domain K08M4_RS08580 1ba7b76c51e40cd9dd3419c7fddfe2c7 629 Gene3D G3DSA:3.10.580.10 151 281 4.0E-29 T 05-07-2017 K08M4_RS08580 1ba7b76c51e40cd9dd3419c7fddfe2c7 629 Pfam PF03445 Putative nucleotidyltransferase DUF294 305 442 3.0E-46 T 05-07-2017 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 K08M4_RS08580 1ba7b76c51e40cd9dd3419c7fddfe2c7 629 Pfam PF00027 Cyclic nucleotide-binding domain 37 119 1.4E-14 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain K08M4_RS08580 1ba7b76c51e40cd9dd3419c7fddfe2c7 629 SMART SM00100 17 134 6.1E-10 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain K08M4_RS08580 1ba7b76c51e40cd9dd3419c7fddfe2c7 629 SUPERFAMILY SSF54631 151 278 3.03E-25 T 05-07-2017 K08M4_RS08580 1ba7b76c51e40cd9dd3419c7fddfe2c7 629 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 479 622 1.7E-45 T 05-07-2017 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding K08M4_RS08580 1ba7b76c51e40cd9dd3419c7fddfe2c7 629 SUPERFAMILY SSF51206 7 127 3.93E-28 T 05-07-2017 IPR018490 Cyclic nucleotide-binding-like K08M4_RS01405 120a62d89f0ab39764bdfb25ee7f0aba 75 Hamap MF_00715 Protein SlyX [slyX]. 8 75 17.862 T 05-07-2017 IPR007236 SlyX K08M4_RS01405 120a62d89f0ab39764bdfb25ee7f0aba 75 Gene3D G3DSA:1.20.5.300 5 55 2.9E-22 T 05-07-2017 K08M4_RS01405 120a62d89f0ab39764bdfb25ee7f0aba 75 Pfam PF04102 SlyX 9 75 4.9E-24 T 05-07-2017 IPR007236 SlyX K08M4_RS07785 32655512d364283ac468612daef2c971 638 Pfam PF16326 ABC transporter C-terminal domain 564 633 8.0E-22 T 05-07-2017 IPR032524 ABC transporter Uup, C-terminal GO:0003677 K08M4_RS07785 32655512d364283ac468612daef2c971 638 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS07785 32655512d364283ac468612daef2c971 638 SUPERFAMILY SSF52540 313 519 2.39E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07785 32655512d364283ac468612daef2c971 638 Pfam PF12848 ABC transporter 224 299 8.5E-11 T 05-07-2017 IPR032781 ABC-transporter extension domain K08M4_RS07785 32655512d364283ac468612daef2c971 638 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS07785 32655512d364283ac468612daef2c971 638 Pfam PF00005 ABC transporter 19 185 2.8E-24 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS07785 32655512d364283ac468612daef2c971 638 Pfam PF00005 ABC transporter 336 469 1.2E-23 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS07785 32655512d364283ac468612daef2c971 638 Gene3D G3DSA:3.40.50.300 2 271 5.2E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07785 32655512d364283ac468612daef2c971 638 Gene3D G3DSA:3.40.50.300 318 549 4.5E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07785 32655512d364283ac468612daef2c971 638 SMART SM00382 28 230 1.5E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS07785 32655512d364283ac468612daef2c971 638 SMART SM00382 344 514 2.4E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS07785 32655512d364283ac468612daef2c971 638 SUPERFAMILY SSF52540 126 239 7.91E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07785 32655512d364283ac468612daef2c971 638 SUPERFAMILY SSF52540 4 94 7.91E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21225 fda67638b25d690ccc78cbd38d73696f 1024 Pfam PF12215 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term 42 454 7.3E-20 T 05-07-2017 IPR024462 Glycosyl-hydrolase family 116, N-terminal KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 K08M4_RS21225 fda67638b25d690ccc78cbd38d73696f 1024 Gene3D G3DSA:1.50.10.10 619 771 1.3E-8 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 K08M4_RS21225 fda67638b25d690ccc78cbd38d73696f 1024 SUPERFAMILY SSF48208 455 734 2.55E-31 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 K08M4_RS21225 fda67638b25d690ccc78cbd38d73696f 1024 SUPERFAMILY SSF48208 812 930 2.55E-31 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 K08M4_RS21225 fda67638b25d690ccc78cbd38d73696f 1024 Pfam PF04685 Glycosyl-hydrolase family 116, catalytic region 509 930 5.3E-62 T 05-07-2017 IPR006775 Glycosyl-hydrolase family 116, catalytic region GO:0004553 KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 K08M4_RS13840 89dc91dd0369b026fd8cb9b627964a4b 400 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS13840 89dc91dd0369b026fd8cb9b627964a4b 400 Pfam PF00005 ABC transporter 43 173 2.0E-18 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS13840 89dc91dd0369b026fd8cb9b627964a4b 400 Gene3D G3DSA:3.40.50.300 31 235 2.8E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13840 89dc91dd0369b026fd8cb9b627964a4b 400 Gene3D G3DSA:2.70.50.60 253 389 8.4E-8 T 05-07-2017 K08M4_RS13840 89dc91dd0369b026fd8cb9b627964a4b 400 SUPERFAMILY SSF52540 27 233 1.96E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13840 89dc91dd0369b026fd8cb9b627964a4b 400 Pfam PF14524 Wzt C-terminal domain 257 390 3.5E-15 T 05-07-2017 IPR029439 Wzt, C-terminal K08M4_RS13840 89dc91dd0369b026fd8cb9b627964a4b 400 SMART SM00382 51 223 4.0E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS10690 281b5307b2dc5394bbdb6839c491504c 214 Hamap MF_00235 Adenylate kinase [adk]. 1 214 51.608 T 05-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 K08M4_RS10690 281b5307b2dc5394bbdb6839c491504c 214 Pfam PF05191 Adenylate kinase, active site lid 123 158 1.2E-13 T 05-07-2017 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 K08M4_RS10690 281b5307b2dc5394bbdb6839c491504c 214 SUPERFAMILY SSF52540 1 190 3.94E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10690 281b5307b2dc5394bbdb6839c491504c 214 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 05-07-2017 K08M4_RS10690 281b5307b2dc5394bbdb6839c491504c 214 PRINTS PR00094 Adenylate kinase signature 173 187 4.3E-35 T 05-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 K08M4_RS10690 281b5307b2dc5394bbdb6839c491504c 214 PRINTS PR00094 Adenylate kinase signature 4 17 4.3E-35 T 05-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 K08M4_RS10690 281b5307b2dc5394bbdb6839c491504c 214 PRINTS PR00094 Adenylate kinase signature 32 46 4.3E-35 T 05-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 K08M4_RS10690 281b5307b2dc5394bbdb6839c491504c 214 PRINTS PR00094 Adenylate kinase signature 156 171 4.3E-35 T 05-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 K08M4_RS10690 281b5307b2dc5394bbdb6839c491504c 214 PRINTS PR00094 Adenylate kinase signature 81 97 4.3E-35 T 05-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 K08M4_RS10690 281b5307b2dc5394bbdb6839c491504c 214 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 1.5E-73 T 05-07-2017 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 K08M4_RS10690 281b5307b2dc5394bbdb6839c491504c 214 Gene3D G3DSA:3.40.50.300 1 212 2.4E-80 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10690 281b5307b2dc5394bbdb6839c491504c 214 Pfam PF00406 Adenylate kinase 5 185 1.4E-58 T 05-07-2017 K08M4_RS15490 1741fc001c7b0d68c6775f64be63b7df 240 SUPERFAMILY SSF55469 1 238 1.7E-73 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 K08M4_RS15490 1741fc001c7b0d68c6775f64be63b7df 240 Gene3D G3DSA:3.40.109.10 1 239 2.0E-77 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 K08M4_RS15490 1741fc001c7b0d68c6775f64be63b7df 240 Pfam PF00881 Nitroreductase family 8 159 1.6E-23 T 05-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 K08M4_RS15490 1741fc001c7b0d68c6775f64be63b7df 240 PIRSF PIRSF005426 1 240 2.7E-84 T 05-07-2017 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 590 705 2.3E-25 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 ProDom PD142495 MEMBRANE SENSOR TRANSFERASE LUXQ 2.7.3.- TRANSMEMBRANE INNER PHOSPHORYLATION SENSORY AUTOINDUCER 12 359 4.0E-84 T 05-07-2017 IPR015387 LuxQ, periplasmic GO:0004673|GO:0016791 K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 Gene3D G3DSA:1.10.287.130 483 530 3.3E-15 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 SUPERFAMILY SSF52172 730 849 2.85E-29 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 SUPERFAMILY SSF103190 51 268 6.51E-66 T 05-07-2017 IPR029151 Periplasmic sensor domain-like K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 Pfam PF09308 LuxQ, periplasmic 40 276 6.0E-104 T 05-07-2017 IPR015387 LuxQ, periplasmic GO:0004673|GO:0016791 K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 650 660 2.0E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 667 685 2.0E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 691 704 2.0E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 632 646 2.0E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 SUPERFAMILY SSF55874 532 706 3.67E-42 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 SMART SM00387 590 707 8.3E-37 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 SMART SM00448 732 844 1.1E-27 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 Gene3D G3DSA:3.40.50.2300 730 846 2.2E-30 T 05-07-2017 K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 Gene3D G3DSA:3.30.450.20 443 482 1.2E-4 T 05-07-2017 K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 Pfam PF00512 His Kinase A (phospho-acceptor) domain 479 543 1.2E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 SMART SM00388 478 543 5.6E-21 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 Pfam PF00072 Response regulator receiver domain 734 843 8.4E-23 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 SUPERFAMILY SSF47384 466 544 1.22E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS16675 2046bc58b8c049098d205f5950332c5d 857 Gene3D G3DSA:3.30.565.10 531 706 2.4E-43 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS02970 bcb64100b912722328f4e6c353e54037 294 Gene3D G3DSA:3.30.420.40 3 77 4.5E-5 T 05-07-2017 K08M4_RS02970 bcb64100b912722328f4e6c353e54037 294 SUPERFAMILY SSF53067 2 111 1.76E-24 T 05-07-2017 K08M4_RS02970 bcb64100b912722328f4e6c353e54037 294 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 6 283 2.0E-45 T 05-07-2017 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 K08M4_RS02970 bcb64100b912722328f4e6c353e54037 294 SUPERFAMILY SSF53067 114 283 1.94E-44 T 05-07-2017 K08M4_RS05410 c12109106413b4117004d93baab0b2b0 409 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 197 207 - T 05-07-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 K08M4_RS05410 c12109106413b4117004d93baab0b2b0 409 SUPERFAMILY SSF53448 7 279 1.43E-69 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS05410 c12109106413b4117004d93baab0b2b0 409 SUPERFAMILY SSF53448 345 361 1.43E-69 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS05410 c12109106413b4117004d93baab0b2b0 409 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 14 33 - T 05-07-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 K08M4_RS05410 c12109106413b4117004d93baab0b2b0 409 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 8 381 8.3E-151 T 05-07-2017 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 K08M4_RS05410 c12109106413b4117004d93baab0b2b0 409 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 5 407 47.963 T 05-07-2017 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 K08M4_RS05410 c12109106413b4117004d93baab0b2b0 409 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 99 107 - T 05-07-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 K08M4_RS05410 c12109106413b4117004d93baab0b2b0 409 Gene3D G3DSA:3.90.550.10 328 371 5.3E-73 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS05410 c12109106413b4117004d93baab0b2b0 409 Gene3D G3DSA:3.90.550.10 10 286 5.3E-73 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS05410 c12109106413b4117004d93baab0b2b0 409 Pfam PF00483 Nucleotidyl transferase 10 277 1.7E-63 T 05-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 K08M4_RS05410 c12109106413b4117004d93baab0b2b0 409 SUPERFAMILY SSF51161 296 402 1.66E-14 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS07935 2bf85738da6e10835e922098d82dd27b 467 SMART SM00283 205 466 1.4E-61 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS07935 2bf85738da6e10835e922098d82dd27b 467 SUPERFAMILY SSF58104 157 461 1.7E-66 T 05-07-2017 K08M4_RS07935 2bf85738da6e10835e922098d82dd27b 467 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 267 461 4.2E-44 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS07935 2bf85738da6e10835e922098d82dd27b 467 Gene3D G3DSA:1.10.287.950 220 434 6.7E-54 T 05-07-2017 K08M4_RS00075 cc0c552a84a6725cb50141708f9c33e3 387 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 05-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 K08M4_RS00075 cc0c552a84a6725cb50141708f9c33e3 387 SUPERFAMILY SSF53901 1 258 3.55E-78 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS00075 cc0c552a84a6725cb50141708f9c33e3 387 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 385 2.1E-141 T 05-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 K08M4_RS00075 cc0c552a84a6725cb50141708f9c33e3 387 Pfam PF00108 Thiolase, N-terminal domain 4 254 4.1E-84 T 05-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 K08M4_RS00075 cc0c552a84a6725cb50141708f9c33e3 387 SUPERFAMILY SSF53901 262 386 1.27E-42 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS00075 cc0c552a84a6725cb50141708f9c33e3 387 Gene3D G3DSA:3.40.47.10 184 267 5.1E-63 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS00075 cc0c552a84a6725cb50141708f9c33e3 387 Gene3D G3DSA:3.40.47.10 4 126 5.1E-63 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS00075 cc0c552a84a6725cb50141708f9c33e3 387 PIRSF PIRSF000429 1 387 3.4E-131 T 05-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 K08M4_RS00075 cc0c552a84a6725cb50141708f9c33e3 387 Hamap MF_01620 3-ketoacyl-CoA thiolase [fadA]. 1 387 60.094 T 05-07-2017 IPR012805 Acetyl-CoA C-acyltransferase FadA GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 K08M4_RS00075 cc0c552a84a6725cb50141708f9c33e3 387 ProSitePatterns PS00737 Thiolases signature 2. 333 349 - T 05-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 K08M4_RS00075 cc0c552a84a6725cb50141708f9c33e3 387 Gene3D G3DSA:3.40.47.10 268 386 4.1E-58 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS00075 cc0c552a84a6725cb50141708f9c33e3 387 Gene3D G3DSA:3.40.47.10 143 183 4.1E-58 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS00075 cc0c552a84a6725cb50141708f9c33e3 387 ProSitePatterns PS00099 Thiolases active site. 368 381 - T 05-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 K08M4_RS00075 cc0c552a84a6725cb50141708f9c33e3 387 TIGRFAM TIGR02445 fadA: acetyl-CoA C-acyltransferase FadA 3 387 3.8E-237 T 05-07-2017 IPR012805 Acetyl-CoA C-acyltransferase FadA GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 K08M4_RS00075 cc0c552a84a6725cb50141708f9c33e3 387 Pfam PF02803 Thiolase, C-terminal domain 262 386 4.6E-48 T 05-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 K08M4_RS10560 c7b7bb22060c7676247e2d25e9a83b98 388 Gene3D G3DSA:3.40.50.261 241 383 7.4E-65 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 K08M4_RS10560 c7b7bb22060c7676247e2d25e9a83b98 388 Pfam PF08442 ATP-grasp domain 2 203 5.9E-78 T 05-07-2017 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 K08M4_RS10560 c7b7bb22060c7676247e2d25e9a83b98 388 Gene3D G3DSA:3.30.470.20 96 239 2.9E-56 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS10560 c7b7bb22060c7676247e2d25e9a83b98 388 Gene3D G3DSA:3.30.1490.20 22 95 3.7E-31 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 K08M4_RS10560 c7b7bb22060c7676247e2d25e9a83b98 388 Pfam PF00549 CoA-ligase 262 382 2.2E-24 T 05-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 K08M4_RS10560 c7b7bb22060c7676247e2d25e9a83b98 388 SUPERFAMILY SSF56059 1 238 2.29E-78 T 05-07-2017 K08M4_RS10560 c7b7bb22060c7676247e2d25e9a83b98 388 PIRSF PIRSF001554 1 388 4.7E-152 T 05-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 K08M4_RS10560 c7b7bb22060c7676247e2d25e9a83b98 388 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 2.0E-171 T 05-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 K08M4_RS10560 c7b7bb22060c7676247e2d25e9a83b98 388 SUPERFAMILY SSF52210 239 385 3.53E-53 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 K08M4_RS10560 c7b7bb22060c7676247e2d25e9a83b98 388 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 05-07-2017 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 K08M4_RS10560 c7b7bb22060c7676247e2d25e9a83b98 388 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 42.02 T 05-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 K08M4_RS17065 14bc51ae463a6c88c082f7da31cfb399 197 Pfam PF05995 Cysteine dioxygenase type I 35 177 4.1E-26 T 05-07-2017 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 K08M4_RS17065 14bc51ae463a6c88c082f7da31cfb399 197 Gene3D G3DSA:2.60.120.10 58 184 2.5E-32 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS17065 14bc51ae463a6c88c082f7da31cfb399 197 SUPERFAMILY SSF51182 35 188 4.89E-37 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 SUPERFAMILY SSF53223 1 122 1.53E-39 T 05-07-2017 K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 260 268 - T 05-07-2017 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 75 102 2.1E-89 T 05-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 110 131 2.1E-89 T 05-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 155 175 2.1E-89 T 05-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 239 255 2.1E-89 T 05-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 204 233 2.1E-89 T 05-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 34 56 2.1E-89 T 05-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 2.1E-89 T 05-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 Gene3D G3DSA:3.40.192.10 7 140 5.3E-50 T 05-07-2017 K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 6 121 1.1E-38 T 05-07-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 Gene3D G3DSA:3.40.50.720 141 264 3.5E-52 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 SUPERFAMILY SSF51735 123 280 2.21E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 76 101 - T 05-07-2017 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 281 7.1E-69 T 05-07-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 K08M4_RS04470 a5d3125a0c17cfa9c06aba59f0c5a046 285 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 37.792 T 05-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 K08M4_RS08095 6b6ab7b3c0df9b2867f63bd8e07ac964 550 SUPERFAMILY SSF55890 334 419 4.84E-10 T 05-07-2017 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 K08M4_RS08095 6b6ab7b3c0df9b2867f63bd8e07ac964 550 Gene3D G3DSA:3.30.450.20 32 175 1.1E-41 T 05-07-2017 K08M4_RS08095 6b6ab7b3c0df9b2867f63bd8e07ac964 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 478 492 1.9E-7 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS08095 6b6ab7b3c0df9b2867f63bd8e07ac964 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 533 546 1.9E-7 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS08095 6b6ab7b3c0df9b2867f63bd8e07ac964 550 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 527 1.9E-7 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS08095 6b6ab7b3c0df9b2867f63bd8e07ac964 550 SUPERFAMILY SSF55785 228 318 1.28E-8 T 05-07-2017 IPR000014 PAS domain K08M4_RS08095 6b6ab7b3c0df9b2867f63bd8e07ac964 550 Gene3D G3DSA:3.30.565.10 404 547 1.1E-22 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08095 6b6ab7b3c0df9b2867f63bd8e07ac964 550 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 434 548 2.1E-13 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08095 6b6ab7b3c0df9b2867f63bd8e07ac964 550 SMART SM00387 430 549 1.1E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08095 6b6ab7b3c0df9b2867f63bd8e07ac964 550 SUPERFAMILY SSF103190 39 180 2.39E-30 T 05-07-2017 IPR029151 Periplasmic sensor domain-like K08M4_RS08095 6b6ab7b3c0df9b2867f63bd8e07ac964 550 Pfam PF17203 Single cache domain 3 36 179 1.8E-18 T 05-07-2017 IPR033463 Single cache domain 3 K08M4_RS08095 6b6ab7b3c0df9b2867f63bd8e07ac964 550 Gene3D G3DSA:1.10.287.130 322 389 1.0E-21 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS08095 6b6ab7b3c0df9b2867f63bd8e07ac964 550 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 332 383 1.2E-9 T 05-07-2017 K08M4_RS08095 6b6ab7b3c0df9b2867f63bd8e07ac964 550 SUPERFAMILY SSF55874 406 546 1.57E-20 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08095 6b6ab7b3c0df9b2867f63bd8e07ac964 550 Gene3D G3DSA:3.30.450.20 230 321 2.3E-7 T 05-07-2017 K08M4_RS05750 1bc78d5d83d5fee25a6a5835af08b56d 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 2.3E-17 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS05750 1bc78d5d83d5fee25a6a5835af08b56d 295 Gene3D G3DSA:3.40.190.10 193 264 5.6E-11 T 05-07-2017 K08M4_RS05750 1bc78d5d83d5fee25a6a5835af08b56d 295 SUPERFAMILY SSF46785 4 87 8.82E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05750 1bc78d5d83d5fee25a6a5835af08b56d 295 Gene3D G3DSA:3.40.190.10 99 192 1.2E-16 T 05-07-2017 K08M4_RS05750 1bc78d5d83d5fee25a6a5835af08b56d 295 Pfam PF03466 LysR substrate binding domain 93 294 1.3E-23 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS05750 1bc78d5d83d5fee25a6a5835af08b56d 295 SUPERFAMILY SSF53850 99 295 1.07E-24 T 05-07-2017 K08M4_RS05750 1bc78d5d83d5fee25a6a5835af08b56d 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.6E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS05750 1bc78d5d83d5fee25a6a5835af08b56d 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.6E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS05750 1bc78d5d83d5fee25a6a5835af08b56d 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.6E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS05750 1bc78d5d83d5fee25a6a5835af08b56d 295 Gene3D G3DSA:1.10.10.10 3 87 2.1E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19545 d8a661c1ebc384738d8cbe4262a1a91d 377 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 328 343 - T 05-07-2017 IPR002114 Phosphotransferase system, HPr serine phosphorylation site K08M4_RS19545 d8a661c1ebc384738d8cbe4262a1a91d 377 SUPERFAMILY SSF55594 292 376 8.9E-24 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS19545 d8a661c1ebc384738d8cbe4262a1a91d 377 SUPERFAMILY SSF55804 145 276 1.44E-17 T 05-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 K08M4_RS19545 d8a661c1ebc384738d8cbe4262a1a91d 377 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 292 370 3.4E-23 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS19545 d8a661c1ebc384738d8cbe4262a1a91d 377 PRINTS PR00107 Phosphocarrier protein signature 327 342 7.4E-19 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS19545 d8a661c1ebc384738d8cbe4262a1a91d 377 PRINTS PR00107 Phosphocarrier protein signature 299 315 7.4E-19 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS19545 d8a661c1ebc384738d8cbe4262a1a91d 377 PRINTS PR00107 Phosphocarrier protein signature 342 359 7.4E-19 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS19545 d8a661c1ebc384738d8cbe4262a1a91d 377 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 299 306 - T 05-07-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site K08M4_RS19545 d8a661c1ebc384738d8cbe4262a1a91d 377 Gene3D G3DSA:3.40.930.10 4 141 2.5E-39 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS19545 d8a661c1ebc384738d8cbe4262a1a91d 377 Gene3D G3DSA:3.40.930.10 149 275 1.5E-12 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS19545 d8a661c1ebc384738d8cbe4262a1a91d 377 SUPERFAMILY SSF55804 4 141 2.09E-38 T 05-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 K08M4_RS19545 d8a661c1ebc384738d8cbe4262a1a91d 377 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 140 4.6E-33 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS19545 d8a661c1ebc384738d8cbe4262a1a91d 377 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 47 63 - T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS19545 d8a661c1ebc384738d8cbe4262a1a91d 377 Gene3D G3DSA:3.30.1340.10 292 376 3.7E-31 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS19545 d8a661c1ebc384738d8cbe4262a1a91d 377 Pfam PF00381 PTS HPr component phosphorylation site 292 370 1.8E-24 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS10490 21eefec97b9a196eb24c9f3b40ea03c1 642 SMART SM00491 477 606 6.9E-45 T 05-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 K08M4_RS10490 21eefec97b9a196eb24c9f3b40ea03c1 642 Gene3D G3DSA:3.40.50.300 20 118 3.6E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10490 21eefec97b9a196eb24c9f3b40ea03c1 642 Gene3D G3DSA:3.40.50.300 191 258 3.6E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10490 21eefec97b9a196eb24c9f3b40ea03c1 642 SMART SM00487 17 288 0.0023 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS10490 21eefec97b9a196eb24c9f3b40ea03c1 642 Pfam PF04851 Type III restriction enzyme, res subunit 19 236 3.9E-5 T 05-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 K08M4_RS10490 21eefec97b9a196eb24c9f3b40ea03c1 642 Pfam PF13307 Helicase C-terminal domain 462 619 1.7E-35 T 05-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 K08M4_RS10490 21eefec97b9a196eb24c9f3b40ea03c1 642 SUPERFAMILY SSF52540 42 89 6.86E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10490 21eefec97b9a196eb24c9f3b40ea03c1 642 SUPERFAMILY SSF52540 480 545 6.86E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10490 21eefec97b9a196eb24c9f3b40ea03c1 642 SUPERFAMILY SSF52540 576 602 6.86E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10490 21eefec97b9a196eb24c9f3b40ea03c1 642 SUPERFAMILY SSF52540 14 235 3.26E-25 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10490 21eefec97b9a196eb24c9f3b40ea03c1 642 Gene3D G3DSA:3.40.50.300 454 602 3.8E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12565 e5842ede05e466cdbfe2cac187dc594d 486 Gene3D G3DSA:3.40.50.720 23 110 1.4E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS12565 e5842ede05e466cdbfe2cac187dc594d 486 Pfam PF01225 Mur ligase family, catalytic domain 25 121 4.4E-27 T 05-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 K08M4_RS12565 e5842ede05e466cdbfe2cac187dc594d 486 Gene3D G3DSA:3.90.190.20 329 474 6.8E-56 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS12565 e5842ede05e466cdbfe2cac187dc594d 486 SUPERFAMILY SSF53623 108 322 8.11E-73 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS12565 e5842ede05e466cdbfe2cac187dc594d 486 SUPERFAMILY SSF51984 16 109 1.26E-28 T 05-07-2017 K08M4_RS12565 e5842ede05e466cdbfe2cac187dc594d 486 SUPERFAMILY SSF53244 326 473 2.75E-46 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS12565 e5842ede05e466cdbfe2cac187dc594d 486 Pfam PF08245 Mur ligase middle domain 127 307 2.1E-28 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS12565 e5842ede05e466cdbfe2cac187dc594d 486 Pfam PF02875 Mur ligase family, glutamate ligase domain 329 417 1.3E-21 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS12565 e5842ede05e466cdbfe2cac187dc594d 486 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 25 473 2.0E-185 T 05-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS12565 e5842ede05e466cdbfe2cac187dc594d 486 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 22 479 43.494 T 05-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS12565 e5842ede05e466cdbfe2cac187dc594d 486 Gene3D G3DSA:3.40.1190.10 111 328 5.0E-83 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS03040 cb1bb0baa953328b1653871d6ec8188e 429 SUPERFAMILY SSF51261 146 388 2.88E-69 T 05-07-2017 IPR011055 Duplicated hybrid motif K08M4_RS03040 cb1bb0baa953328b1653871d6ec8188e 429 Pfam PF08525 Opacity-associated protein A N-terminal motif 4 32 2.5E-5 T 05-07-2017 IPR013731 Opacity-associated protein A, N-terminal K08M4_RS03040 cb1bb0baa953328b1653871d6ec8188e 429 Pfam PF01551 Peptidase family M23 295 386 1.0E-30 T 05-07-2017 IPR016047 Peptidase M23 K08M4_RS03040 cb1bb0baa953328b1653871d6ec8188e 429 Gene3D G3DSA:2.70.70.10 250 388 1.6E-43 T 05-07-2017 K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 SMART SM00926 41 95 8.6E-14 T 05-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 Gene3D G3DSA:2.20.25.90 38 97 2.0E-20 T 05-07-2017 K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 42 94 8.4E-17 T 05-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 46 63 - T 05-07-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 TIGRFAM TIGR01706 NAPA: periplasmic nitrate reductase, large subunit 2 828 0.0 T 05-07-2017 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042128|GO:0042597|GO:0051539|GO:0055114 KEGG: 00910+1.7.99.4 K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 SUPERFAMILY SSF50692 688 828 2.49E-43 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 Hamap MF_01630 Nitrate reductase [napA]. 1 828 28.936 T 05-07-2017 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042128|GO:0042597|GO:0051539|GO:0055114 KEGG: 00910+1.7.99.4 K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 Gene3D G3DSA:2.40.40.20 669 828 1.1E-45 T 05-07-2017 K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 Gene3D G3DSA:3.40.228.10 327 399 6.8E-56 T 05-07-2017 K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 Gene3D G3DSA:3.40.228.10 181 293 6.8E-56 T 05-07-2017 K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 SUPERFAMILY SSF53706 38 650 1.23E-200 T 05-07-2017 K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 Pfam PF00384 Molybdopterin oxidoreductase 98 570 1.2E-91 T 05-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 Pfam PF01568 Molydopterin dinucleotide binding domain 714 822 2.3E-27 T 05-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 Gene3D G3DSA:3.40.50.740 621 668 3.3E-79 T 05-07-2017 K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 Gene3D G3DSA:3.40.50.740 98 180 3.3E-79 T 05-07-2017 K08M4_RS17835 17ac9610fa30654d8f8c2b5fa88c9be7 829 Gene3D G3DSA:3.40.50.740 400 577 3.3E-79 T 05-07-2017 K08M4_RS02905 ff81f6d7a1e3afc9a1f5eafda2256715 832 Gene3D G3DSA:3.40.50.300 14 171 3.9E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02905 ff81f6d7a1e3afc9a1f5eafda2256715 832 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 15 829 0.0 T 05-07-2017 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type K08M4_RS02905 ff81f6d7a1e3afc9a1f5eafda2256715 832 PIRSF PIRSF005496 11 831 0.0 T 05-07-2017 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type K08M4_RS02905 ff81f6d7a1e3afc9a1f5eafda2256715 832 SMART SM00487 9 197 9.9E-14 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS02905 ff81f6d7a1e3afc9a1f5eafda2256715 832 SMART SM00490 237 338 1.3E-16 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS02905 ff81f6d7a1e3afc9a1f5eafda2256715 832 SUPERFAMILY SSF52540 33 468 8.15E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02905 ff81f6d7a1e3afc9a1f5eafda2256715 832 Pfam PF08482 ATP-dependent helicase C-terminal 685 817 3.0E-52 T 05-07-2017 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal K08M4_RS02905 ff81f6d7a1e3afc9a1f5eafda2256715 832 Pfam PF04408 Helicase associated domain (HA2) 399 458 7.2E-10 T 05-07-2017 IPR007502 Helicase-associated domain GO:0004386 K08M4_RS02905 ff81f6d7a1e3afc9a1f5eafda2256715 832 Pfam PF00271 Helicase conserved C-terminal domain 210 337 2.2E-13 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS02905 ff81f6d7a1e3afc9a1f5eafda2256715 832 Pfam PF00270 DEAD/DEAH box helicase 21 173 7.9E-8 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS02905 ff81f6d7a1e3afc9a1f5eafda2256715 832 Gene3D G3DSA:3.40.50.300 209 350 9.5E-16 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02905 ff81f6d7a1e3afc9a1f5eafda2256715 832 SMART SM00847 398 488 7.6E-11 T 05-07-2017 IPR007502 Helicase-associated domain GO:0004386 K08M4_RS16610 51936e983798f90790e9650965e77572 306 SUPERFAMILY SSF46785 3 84 1.15E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16610 51936e983798f90790e9650965e77572 306 Gene3D G3DSA:1.10.10.10 3 84 5.4E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16610 51936e983798f90790e9650965e77572 306 Pfam PF03466 LysR substrate binding domain 91 290 2.2E-22 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS16610 51936e983798f90790e9650965e77572 306 SUPERFAMILY SSF53850 88 293 3.62E-39 T 05-07-2017 K08M4_RS16610 51936e983798f90790e9650965e77572 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 5.5E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS16610 51936e983798f90790e9650965e77572 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 5.5E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS16610 51936e983798f90790e9650965e77572 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 5.5E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS16610 51936e983798f90790e9650965e77572 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 5.3E-17 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS16610 51936e983798f90790e9650965e77572 306 Gene3D G3DSA:3.40.190.10 88 169 2.8E-23 T 05-07-2017 K08M4_RS16610 51936e983798f90790e9650965e77572 306 Gene3D G3DSA:3.40.190.10 271 298 2.8E-23 T 05-07-2017 K08M4_RS16610 51936e983798f90790e9650965e77572 306 Gene3D G3DSA:3.40.190.10 170 266 3.5E-26 T 05-07-2017 K08M4_RS09345 4250392af7e750eedcd4d5db4750252c 540 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 455 9.0E-81 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain K08M4_RS09345 4250392af7e750eedcd4d5db4750252c 540 SUPERFAMILY SSF53850 34 535 1.54E-127 T 05-07-2017 K08M4_RS09345 4250392af7e750eedcd4d5db4750252c 540 Gene3D G3DSA:3.90.76.10 41 222 2.6E-43 T 05-07-2017 K08M4_RS09345 4250392af7e750eedcd4d5db4750252c 540 PIRSF PIRSF002741 1 539 1.4E-92 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 K08M4_RS09345 4250392af7e750eedcd4d5db4750252c 540 Gene3D G3DSA:3.10.105.10 293 508 6.6E-55 T 05-07-2017 K08M4_RS21050 e21baed4e8b7e14a91d5252401859d12 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 05-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 K08M4_RS21050 e21baed4e8b7e14a91d5252401859d12 506 SUPERFAMILY SSF53720 14 497 6.54E-164 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 K08M4_RS21050 e21baed4e8b7e14a91d5252401859d12 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 05-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 K08M4_RS21050 e21baed4e8b7e14a91d5252401859d12 506 Pfam PF00171 Aldehyde dehydrogenase family 27 493 1.4E-166 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS21050 e21baed4e8b7e14a91d5252401859d12 506 Gene3D G3DSA:3.40.309.10 270 469 5.1E-64 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 K08M4_RS21050 e21baed4e8b7e14a91d5252401859d12 506 Gene3D G3DSA:3.40.605.10 18 269 7.6E-92 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 Pfam PF11638 DnaA N-terminal domain 4 65 4.6E-19 T 05-07-2017 IPR024633 DnaA N-terminal domain K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 SUPERFAMILY SSF48295 369 472 1.31E-37 T 05-07-2017 IPR010921 Trp repressor/replication initiator GO:0043565 K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 SUPERFAMILY SSF52540 138 349 1.18E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 SMART SM00382 170 383 4.7E-7 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 382 450 1.8E-32 T 05-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 ProSitePatterns PS01008 DnaA protein signature. 431 450 - T 05-07-2017 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 171 191 1.7E-54 T 05-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 203 217 1.7E-54 T 05-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 431 450 1.7E-54 T 05-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 235 249 1.7E-54 T 05-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 269 296 1.7E-54 T 05-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 6 471 1.5E-186 T 05-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 3 472 34.357 T 05-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 Gene3D G3DSA:1.10.1750.10 372 472 2.6E-42 T 05-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 Gene3D G3DSA:1.10.8.60 304 371 1.1E-30 T 05-07-2017 K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 SMART SM00760 381 450 3.4E-45 T 05-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 Pfam PF00308 Bacterial dnaA protein 139 355 1.1E-97 T 05-07-2017 IPR013317 Chromosomal replication initiator protein DnaA K08M4_RS00005 dde4b0807a60bb5d268e01938b0281fc 473 Gene3D G3DSA:3.40.50.300 133 302 1.9E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 890 950 3.4E-18 T 05-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 SUPERFAMILY SSF47323 642 904 1.48E-64 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 1.2E-33 T 05-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 PRINTS PR00986 Valyl-tRNA synthetase signature 469 490 1.2E-33 T 05-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 PRINTS PR00986 Valyl-tRNA synthetase signature 35 46 1.2E-33 T 05-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 PRINTS PR00986 Valyl-tRNA synthetase signature 369 382 1.2E-33 T 05-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 PRINTS PR00986 Valyl-tRNA synthetase signature 500 518 1.2E-33 T 05-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 Pfam PF08264 Anticodon-binding domain of tRNA 679 832 1.1E-39 T 05-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 Gene3D G3DSA:3.40.50.620 3 193 9.4E-139 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 Gene3D G3DSA:3.40.50.620 609 630 9.4E-139 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 Gene3D G3DSA:3.40.50.620 364 571 9.4E-139 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 SUPERFAMILY SSF50677 191 365 8.5E-58 T 05-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 Hamap MF_02004 Valine--tRNA ligase [valS]. 1 955 15.981 T 05-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 Gene3D G3DSA:1.10.287.380 884 949 1.4E-5 T 05-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 631 8.6E-220 T 05-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 TIGRFAM TIGR00422 valS: valine--tRNA ligase 1 938 0.0 T 05-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 SUPERFAMILY SSF46589 890 954 4.34E-18 T 05-07-2017 IPR010978 tRNA-binding arm GO:0000166 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 Gene3D G3DSA:3.90.740.10 194 360 1.2E-46 T 05-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 SUPERFAMILY SSF52374 364 571 1.4E-134 T 05-07-2017 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 SUPERFAMILY SSF52374 1 192 1.4E-134 T 05-07-2017 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 SUPERFAMILY SSF52374 609 641 1.4E-134 T 05-07-2017 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 Gene3D G3DSA:1.10.730.10 631 821 1.4E-60 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS01930 16ce53361c6e38d3be2e03f453b61b4f 957 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 05-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS09865 569310ceee9a3665ea11225c5095a2b0 288 SUPERFAMILY SSF56112 25 269 1.6E-30 T 05-07-2017 IPR011009 Protein kinase-like domain K08M4_RS09865 569310ceee9a3665ea11225c5095a2b0 288 Gene3D G3DSA:3.90.1200.10 83 265 9.9E-10 T 05-07-2017 K08M4_RS09865 569310ceee9a3665ea11225c5095a2b0 288 Pfam PF01636 Phosphotransferase enzyme family 31 216 1.9E-8 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase K08M4_RS17690 4dcf79cba6e85ee7e44029821f9c664a 196 Pfam PF16925 Bacterial transcriptional repressor C-terminal 103 186 2.0E-8 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal K08M4_RS17690 4dcf79cba6e85ee7e44029821f9c664a 196 Gene3D G3DSA:1.10.357.10 7 193 1.3E-34 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS17690 4dcf79cba6e85ee7e44029821f9c664a 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 3.9E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS17690 4dcf79cba6e85ee7e44029821f9c664a 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 3.9E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS17690 4dcf79cba6e85ee7e44029821f9c664a 196 SUPERFAMILY SSF48498 80 192 4.82E-19 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal K08M4_RS17690 4dcf79cba6e85ee7e44029821f9c664a 196 SUPERFAMILY SSF46689 3 72 6.67E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS17690 4dcf79cba6e85ee7e44029821f9c664a 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 4.0E-11 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS19270 5851616add1a6c3980cef0794063ae8f 519 Gene3D G3DSA:3.30.1120.10 384 423 8.0E-4 T 05-07-2017 K08M4_RS19270 5851616add1a6c3980cef0794063ae8f 519 SUPERFAMILY SSF53649 23 471 3.93E-114 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 K08M4_RS19270 5851616add1a6c3980cef0794063ae8f 519 Gene3D G3DSA:3.40.720.10 24 383 2.9E-94 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 K08M4_RS19270 5851616add1a6c3980cef0794063ae8f 519 Pfam PF00884 Sulfatase 27 352 8.2E-63 T 05-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 K08M4_RS11140 c4142635faf8436a9acc80cc380d4d64 446 Pfam PF09179 TilS substrate binding domain 250 317 2.0E-17 T 05-07-2017 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 K08M4_RS11140 c4142635faf8436a9acc80cc380d4d64 446 SUPERFAMILY SSF82829 247 321 1.18E-24 T 05-07-2017 K08M4_RS11140 c4142635faf8436a9acc80cc380d4d64 446 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 21 203 9.1E-51 T 05-07-2017 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 K08M4_RS11140 c4142635faf8436a9acc80cc380d4d64 446 SUPERFAMILY SSF52402 18 233 8.56E-59 T 05-07-2017 K08M4_RS11140 c4142635faf8436a9acc80cc380d4d64 446 SMART SM00977 375 446 1.4E-22 T 05-07-2017 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 K08M4_RS11140 c4142635faf8436a9acc80cc380d4d64 446 SUPERFAMILY SSF56037 325 444 7.59E-30 T 05-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 K08M4_RS11140 c4142635faf8436a9acc80cc380d4d64 446 Pfam PF01171 PP-loop family 22 200 1.5E-55 T 05-07-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 K08M4_RS11140 c4142635faf8436a9acc80cc380d4d64 446 Gene3D G3DSA:3.40.50.620 18 180 1.2E-12 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS11140 c4142635faf8436a9acc80cc380d4d64 446 Pfam PF11734 TilS substrate C-terminal domain 375 444 2.0E-25 T 05-07-2017 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 K08M4_RS11140 c4142635faf8436a9acc80cc380d4d64 446 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 5 309 22.539 T 05-07-2017 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 K08M4_RS11140 c4142635faf8436a9acc80cc380d4d64 446 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 375 421 8.9E-18 T 05-07-2017 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 K08M4_RS10140 570f74935cd1d3fc36cd23c1dccfa911 181 ProSitePatterns PS00460 Glutathione peroxidases active site. 50 65 - T 05-07-2017 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 K08M4_RS10140 570f74935cd1d3fc36cd23c1dccfa911 181 SUPERFAMILY SSF52833 39 181 1.56E-40 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS10140 570f74935cd1d3fc36cd23c1dccfa911 181 PIRSF PIRSF000303 1 181 6.8E-54 T 05-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 K08M4_RS10140 570f74935cd1d3fc36cd23c1dccfa911 181 Pfam PF00255 Glutathione peroxidase 45 133 1.5E-24 T 05-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 K08M4_RS10140 570f74935cd1d3fc36cd23c1dccfa911 181 Gene3D G3DSA:3.40.30.10 39 181 8.3E-45 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS10140 570f74935cd1d3fc36cd23c1dccfa911 181 PRINTS PR01011 Glutathione peroxidase family signature 143 152 1.3E-11 T 05-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 K08M4_RS10140 570f74935cd1d3fc36cd23c1dccfa911 181 PRINTS PR01011 Glutathione peroxidase family signature 48 65 1.3E-11 T 05-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 K08M4_RS10140 570f74935cd1d3fc36cd23c1dccfa911 181 PRINTS PR01011 Glutathione peroxidase family signature 83 99 1.3E-11 T 05-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 K08M4_RS03525 27e70fd418d6785f6c6b868d9dcad25c 168 Pfam PF04608 Phosphatidylglycerophosphatase A 15 160 2.1E-52 T 05-07-2017 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 K08M4_RS03525 27e70fd418d6785f6c6b868d9dcad25c 168 PIRSF PIRSF006162 6 167 7.8E-55 T 05-07-2017 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668 K08M4_RS03525 27e70fd418d6785f6c6b868d9dcad25c 168 Gene3D G3DSA:1.10.3760.10 114 156 2.0E-4 T 05-07-2017 IPR027416 YutG-like domain K08M4_RS03525 27e70fd418d6785f6c6b868d9dcad25c 168 SUPERFAMILY SSF101307 9 160 1.28E-49 T 05-07-2017 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 K08M4_RS01675 64f7d38d79e1bf0784b206d6361afa04 574 Gene3D G3DSA:3.30.70.1450 207 287 1.3E-17 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS01675 64f7d38d79e1bf0784b206d6361afa04 574 Gene3D G3DSA:3.30.70.1450 290 349 1.5E-14 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS01675 64f7d38d79e1bf0784b206d6361afa04 574 SUPERFAMILY SSF116726 206 283 1.83E-16 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS01675 64f7d38d79e1bf0784b206d6361afa04 574 Pfam PF02080 TrkA-C domain 209 278 5.7E-13 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS01675 64f7d38d79e1bf0784b206d6361afa04 574 Pfam PF02080 TrkA-C domain 293 349 7.4E-11 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS01675 64f7d38d79e1bf0784b206d6361afa04 574 SUPERFAMILY SSF116726 289 349 1.96E-13 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS01675 64f7d38d79e1bf0784b206d6361afa04 574 Pfam PF03600 Citrate transporter 31 518 5.3E-26 T 05-07-2017 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 K08M4_RS00070 73e1e74780565aaf7267fe601a87d547 326 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 3 326 7.0E-136 T 05-07-2017 IPR014188 Acrylyl-CoA reductase AcuI K08M4_RS00070 73e1e74780565aaf7267fe601a87d547 326 SMART SM00829 13 324 3.9E-4 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 K08M4_RS00070 73e1e74780565aaf7267fe601a87d547 326 SUPERFAMILY SSF50129 2 145 8.13E-43 T 05-07-2017 IPR011032 GroES-like K08M4_RS00070 73e1e74780565aaf7267fe601a87d547 326 Gene3D G3DSA:3.40.50.720 140 292 7.4E-76 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS00070 73e1e74780565aaf7267fe601a87d547 326 SUPERFAMILY SSF51735 116 289 4.29E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS00070 73e1e74780565aaf7267fe601a87d547 326 Pfam PF00107 Zinc-binding dehydrogenase 159 280 3.8E-13 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 K08M4_RS00070 73e1e74780565aaf7267fe601a87d547 326 Gene3D G3DSA:3.90.180.10 17 139 4.4E-8 T 05-07-2017 IPR011032 GroES-like K08M4_RS11025 58288dfd1b655910aeae1bce835d2ded 79 SUPERFAMILY SSF64307 5 72 2.88E-11 T 05-07-2017 IPR001455 TusA-like domain K08M4_RS11025 58288dfd1b655910aeae1bce835d2ded 79 Gene3D G3DSA:3.30.110.40 4 73 5.3E-12 T 05-07-2017 IPR001455 TusA-like domain K08M4_RS11025 58288dfd1b655910aeae1bce835d2ded 79 Pfam PF01206 Sulfurtransferase TusA 5 72 9.1E-13 T 05-07-2017 IPR001455 TusA-like domain K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 SUPERFAMILY SSF88697 10 200 1.39E-47 T 05-07-2017 IPR015947 PUA-like domain K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 SUPERFAMILY SSF54211 594 769 1.9E-58 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 Gene3D G3DSA:1.10.8.60 500 582 8.6E-33 T 05-07-2017 K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 Gene3D G3DSA:3.30.230.10 589 770 6.6E-77 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 Hamap MF_01973 Lon protease [lon]. 11 771 71.453 T 05-07-2017 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 569 771 1.0E-98 T 05-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 SMART SM00382 347 491 6.3E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 SMART SM00464 10 201 5.5E-74 T 05-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 594 610 1.8E-56 T 05-07-2017 K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 702 721 1.8E-56 T 05-07-2017 K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 355 374 1.8E-56 T 05-07-2017 K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 672 691 1.8E-56 T 05-07-2017 K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 725 743 1.8E-56 T 05-07-2017 K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 PIRSF PIRSF001174 1 774 0.0 T 05-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 SUPERFAMILY SSF52540 312 586 6.86E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 675 683 - T 05-07-2017 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 TIGRFAM TIGR00763 lon: endopeptidase La 12 770 0.0 T 05-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 10 196 1.4E-40 T 05-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 Gene3D G3DSA:3.40.50.300 310 499 2.1E-32 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10380 6a79be9f94a3fcd3b0a0292b378c938c 783 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 351 487 1.2E-16 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 K08M4_RS16400 282fa9370537eaf0e362b5a7bcaead75 456 Pfam PF07670 Nucleoside recognition 142 235 3.6E-8 T 05-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 K08M4_RS17340 82a25f8dc6fc185a9752b0de1ef592e4 217 Gene3D G3DSA:1.10.286.10 4 84 1.3E-32 T 05-07-2017 K08M4_RS17340 82a25f8dc6fc185a9752b0de1ef592e4 217 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 38 216 5.3E-79 T 05-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 K08M4_RS17340 82a25f8dc6fc185a9752b0de1ef592e4 217 Gene3D G3DSA:3.30.1130.10 90 216 6.6E-50 T 05-07-2017 K08M4_RS17340 82a25f8dc6fc185a9752b0de1ef592e4 217 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 34 217 33.543 T 05-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 K08M4_RS17340 82a25f8dc6fc185a9752b0de1ef592e4 217 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 144 154 - T 05-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 K08M4_RS17340 82a25f8dc6fc185a9752b0de1ef592e4 217 SUPERFAMILY SSF55620 8 216 7.41E-74 T 05-07-2017 K08M4_RS17340 82a25f8dc6fc185a9752b0de1ef592e4 217 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 96 112 - T 05-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 K08M4_RS17340 82a25f8dc6fc185a9752b0de1ef592e4 217 Pfam PF01227 GTP cyclohydrolase I 38 215 1.6E-62 T 05-07-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 K08M4_RS17940 ff3da07457ee2517f733b37330962902 481 Pfam PF05762 VWA domain containing CoxE-like protein 320 447 5.6E-9 T 05-07-2017 IPR008912 Uncharacterised protein family CoxE-like K08M4_RS17940 ff3da07457ee2517f733b37330962902 481 SUPERFAMILY SSF53300 318 475 1.3E-26 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS17940 ff3da07457ee2517f733b37330962902 481 SMART SM00327 320 479 0.0017 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 Pfam PF03129 Anticodon binding domain 475 568 1.2E-21 T 05-07-2017 IPR004154 Anticodon-binding K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 Gene3D G3DSA:3.90.960.10 252 388 1.8E-31 T 05-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 SUPERFAMILY SSF55826 218 390 7.98E-31 T 05-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 571 40.997 T 05-07-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 568 1.5E-242 T 05-07-2017 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 459 5.5E-40 T 05-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 SUPERFAMILY SSF55681 407 478 1.03E-98 T 05-07-2017 K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 SUPERFAMILY SSF55681 10 237 1.03E-98 T 05-07-2017 K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 PIRSF PIRSF001535 1 571 1.1E-263 T 05-07-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 Gene3D G3DSA:3.30.930.10 389 472 1.0E-101 T 05-07-2017 K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 Gene3D G3DSA:3.30.930.10 10 234 1.0E-101 T 05-07-2017 K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 8.3E-17 T 05-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 8.3E-17 T 05-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 8.3E-17 T 05-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 8.3E-17 T 05-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 Gene3D G3DSA:3.40.50.800 473 570 3.1E-33 T 05-07-2017 IPR004154 Anticodon-binding K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 SUPERFAMILY SSF52954 463 570 2.11E-32 T 05-07-2017 IPR004154 Anticodon-binding K08M4_RS11310 13e535959bdeedc116a0d49fd34b055f 571 Pfam PF04073 Aminoacyl-tRNA editing domain 257 378 9.0E-26 T 05-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 Gene3D G3DSA:2.40.30.10 287 390 3.9E-26 T 05-07-2017 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 SUPERFAMILY SSF54292 515 617 3.8E-25 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 Pfam PF03473 MOSC domain 150 273 7.4E-30 T 05-07-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 SUPERFAMILY SSF63380 286 395 1.32E-25 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 Gene3D G3DSA:3.10.20.30 521 617 3.1E-26 T 05-07-2017 IPR012675 Beta-grasp domain K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 547 610 3.9E-12 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 PRINTS PR00410 Phenol hydroxylase reductase family signature 322 334 2.8E-7 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 PRINTS PR00410 Phenol hydroxylase reductase family signature 385 394 2.8E-7 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 PRINTS PR00410 Phenol hydroxylase reductase family signature 491 499 2.8E-7 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 PRINTS PR00410 Phenol hydroxylase reductase family signature 401 420 2.8E-7 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 Pfam PF03476 MOSC N-terminal beta barrel domain 16 129 3.2E-29 T 05-07-2017 IPR005303 MOSC, N-terminal beta barrel K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 568 576 - T 05-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 Pfam PF00175 Oxidoreductase NAD-binding domain 402 505 8.1E-17 T 05-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 SUPERFAMILY SSF141673 17 144 1.2E-28 T 05-07-2017 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 SUPERFAMILY SSF50800 159 275 3.14E-15 T 05-07-2017 IPR011037 Pyruvate kinase-like, insert domain K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 SUPERFAMILY SSF50800 12 63 3.14E-15 T 05-07-2017 IPR011037 Pyruvate kinase-like, insert domain K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 SUPERFAMILY SSF52343 394 525 3.14E-34 T 05-07-2017 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 322 332 9.7E-8 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 401 420 9.7E-8 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 438 449 9.7E-8 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 341 348 9.7E-8 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 491 499 9.7E-8 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 Pfam PF00970 Oxidoreductase FAD-binding domain 294 391 6.7E-16 T 05-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 K08M4_RS16280 d5334d57750cd1bade85ed66f30382a6 618 Gene3D G3DSA:3.40.50.80 391 520 1.3E-35 T 05-07-2017 K08M4_RS12620 86b45bf1344b59071043b0e8dc0cd227 288 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 91 102 - T 05-07-2017 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS12620 86b45bf1344b59071043b0e8dc0cd227 288 Gene3D G3DSA:3.40.1010.10 13 121 1.5E-15 T 05-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS12620 86b45bf1344b59071043b0e8dc0cd227 288 SUPERFAMILY SSF53790 12 232 6.15E-86 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS12620 86b45bf1344b59071043b0e8dc0cd227 288 Gene3D G3DSA:3.30.950.10 122 235 7.5E-45 T 05-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS12620 86b45bf1344b59071043b0e8dc0cd227 288 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 13 213 7.5E-30 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS12620 86b45bf1344b59071043b0e8dc0cd227 288 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 14 285 5.0E-101 T 05-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS12620 86b45bf1344b59071043b0e8dc0cd227 288 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 13 234 38.667 T 05-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS12620 86b45bf1344b59071043b0e8dc0cd227 288 PIRSF PIRSF005917 1 287 1.8E-108 T 05-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS21295 79623c1f9555579a7aa6b744e5473229 379 SUPERFAMILY SSF51395 7 375 2.01E-96 T 05-07-2017 K08M4_RS21295 79623c1f9555579a7aa6b744e5473229 379 PIRSF PIRSF000138 2 378 3.4E-121 T 05-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 K08M4_RS21295 79623c1f9555579a7aa6b744e5473229 379 Gene3D G3DSA:3.20.20.70 7 375 3.3E-131 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS21295 79623c1f9555579a7aa6b744e5473229 379 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 273 279 - T 05-07-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 K08M4_RS21295 79623c1f9555579a7aa6b744e5473229 379 Pfam PF01070 FMN-dependent dehydrogenase 13 375 1.8E-124 T 05-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 K08M4_RS19825 0c47452a06301081633548d8e8ad12a9 224 Pfam PF00043 Glutathione S-transferase, C-terminal domain 124 191 4.4E-13 T 05-07-2017 IPR004046 Glutathione S-transferase, C-terminal K08M4_RS19825 0c47452a06301081633548d8e8ad12a9 224 Gene3D G3DSA:1.20.1050.10 80 192 1.1E-37 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS19825 0c47452a06301081633548d8e8ad12a9 224 Pfam PF02798 Glutathione S-transferase, N-terminal domain 7 73 4.0E-15 T 05-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 K08M4_RS19825 0c47452a06301081633548d8e8ad12a9 224 SUPERFAMILY SSF52833 1 81 3.75E-23 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS19825 0c47452a06301081633548d8e8ad12a9 224 SUPERFAMILY SSF47616 80 196 3.68E-31 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS19825 0c47452a06301081633548d8e8ad12a9 224 Gene3D G3DSA:3.40.30.10 1 77 2.0E-26 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS12925 fa8c3c2c54f4edf2def96fe40964021a 363 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 7 356 9.4E-164 T 05-07-2017 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 K08M4_RS12925 fa8c3c2c54f4edf2def96fe40964021a 363 Gene3D G3DSA:3.40.718.10 3 360 5.6E-133 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 K08M4_RS12925 fa8c3c2c54f4edf2def96fe40964021a 363 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 6 360 50.741 T 05-07-2017 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 K08M4_RS12925 fa8c3c2c54f4edf2def96fe40964021a 363 SUPERFAMILY SSF53659 4 360 2.5E-123 T 05-07-2017 K08M4_RS12925 fa8c3c2c54f4edf2def96fe40964021a 363 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 248 267 - T 05-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 K08M4_RS12925 fa8c3c2c54f4edf2def96fe40964021a 363 SMART SM01329 7 356 9.7E-201 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 K08M4_RS12925 fa8c3c2c54f4edf2def96fe40964021a 363 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 356 2.2E-137 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 K08M4_RS01820 2b00effb18c706dd4ff5ce4e384025e7 164 Gene3D G3DSA:2.60.450.10 21 156 3.0E-36 T 05-07-2017 K08M4_RS01820 2b00effb18c706dd4ff5ce4e384025e7 164 Pfam PF03968 OstA-like protein 30 141 1.0E-28 T 05-07-2017 IPR005653 Organic solvent tolerance-like, N-terminal K08M4_RS01820 2b00effb18c706dd4ff5ce4e384025e7 164 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 1 160 24.162 T 05-07-2017 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 K08M4_RS01820 2b00effb18c706dd4ff5ce4e384025e7 164 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 20 159 4.3E-47 T 05-07-2017 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 K08M4_RS00920 191e8f7e3a098fe03bb9245e6ea0ae60 447 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 1.6E-36 T 05-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 K08M4_RS00920 191e8f7e3a098fe03bb9245e6ea0ae60 447 Gene3D G3DSA:3.30.1490.20 130 203 4.0E-29 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 K08M4_RS00920 191e8f7e3a098fe03bb9245e6ea0ae60 447 SUPERFAMILY SSF56059 83 349 2.36E-70 T 05-07-2017 K08M4_RS00920 191e8f7e3a098fe03bb9245e6ea0ae60 447 Gene3D G3DSA:3.40.50.20 1 129 1.6E-48 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS00920 191e8f7e3a098fe03bb9245e6ea0ae60 447 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 K08M4_RS00920 191e8f7e3a098fe03bb9245e6ea0ae60 447 SUPERFAMILY SSF52440 1 113 1.65E-45 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS00920 191e8f7e3a098fe03bb9245e6ea0ae60 447 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 K08M4_RS00920 191e8f7e3a098fe03bb9245e6ea0ae60 447 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 4.9E-43 T 05-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 K08M4_RS00920 191e8f7e3a098fe03bb9245e6ea0ae60 447 Gene3D G3DSA:3.30.470.20 204 444 1.9E-99 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS00920 191e8f7e3a098fe03bb9245e6ea0ae60 447 SMART SM00878 336 441 5.9E-62 T 05-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 K08M4_RS00920 191e8f7e3a098fe03bb9245e6ea0ae60 447 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 2.5E-83 T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 K08M4_RS00920 191e8f7e3a098fe03bb9245e6ea0ae60 447 SUPERFAMILY SSF51246 331 444 3.61E-41 T 05-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 K08M4_RS00920 191e8f7e3a098fe03bb9245e6ea0ae60 447 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 1.1E-240 T 05-07-2017 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 K08M4_RS19225 79b27fdc875e253f1c871a2095a9a6fe 301 Gene3D G3DSA:3.40.190.10 171 266 5.4E-20 T 05-07-2017 K08M4_RS19225 79b27fdc875e253f1c871a2095a9a6fe 301 Pfam PF03466 LysR substrate binding domain 95 295 2.9E-19 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS19225 79b27fdc875e253f1c871a2095a9a6fe 301 SUPERFAMILY SSF53850 88 294 1.14E-34 T 05-07-2017 K08M4_RS19225 79b27fdc875e253f1c871a2095a9a6fe 301 SUPERFAMILY SSF46785 4 83 9.84E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19225 79b27fdc875e253f1c871a2095a9a6fe 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.6E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19225 79b27fdc875e253f1c871a2095a9a6fe 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.6E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19225 79b27fdc875e253f1c871a2095a9a6fe 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.6E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19225 79b27fdc875e253f1c871a2095a9a6fe 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 1.4E-18 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19225 79b27fdc875e253f1c871a2095a9a6fe 301 Gene3D G3DSA:1.10.10.10 2 83 1.1E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19225 79b27fdc875e253f1c871a2095a9a6fe 301 Gene3D G3DSA:3.40.190.10 88 170 1.2E-25 T 05-07-2017 K08M4_RS19225 79b27fdc875e253f1c871a2095a9a6fe 301 Gene3D G3DSA:3.40.190.10 271 298 1.2E-25 T 05-07-2017 K08M4_RS13550 907e311480b99c8365ff077844d23337 392 Gene3D G3DSA:3.30.70.20 187 262 3.7E-8 T 05-07-2017 K08M4_RS13550 907e311480b99c8365ff077844d23337 392 Pfam PF13484 4Fe-4S double cluster binding domain 189 252 4.9E-20 T 05-07-2017 K08M4_RS13550 907e311480b99c8365ff077844d23337 392 Pfam PF08331 Domain of unknown function (DUF1730) 58 136 1.7E-22 T 05-07-2017 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 K08M4_RS13550 907e311480b99c8365ff077844d23337 392 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 3 311 49.785 T 05-07-2017 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 K08M4_RS13550 907e311480b99c8365ff077844d23337 392 SUPERFAMILY SSF54862 165 319 1.05E-19 T 05-07-2017 K08M4_RS13550 907e311480b99c8365ff077844d23337 392 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 10 344 3.1E-147 T 05-07-2017 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 K08M4_RS13550 907e311480b99c8365ff077844d23337 392 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 189 200 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS15440 33fdc528e2c653ff54e1cb4c4666943a 129 SUPERFAMILY SSF54593 1 128 1.48E-25 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS15440 33fdc528e2c653ff54e1cb4c4666943a 129 Gene3D G3DSA:3.10.180.10 1 128 1.8E-36 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS15440 33fdc528e2c653ff54e1cb4c4666943a 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 127 2.8E-11 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain K08M4_RS12465 558aeb3de4f1d3424328d68ada3a61ee 489 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 5.3E-23 T 05-07-2017 K08M4_RS12465 558aeb3de4f1d3424328d68ada3a61ee 489 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 5.3E-23 T 05-07-2017 K08M4_RS12465 558aeb3de4f1d3424328d68ada3a61ee 489 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 5.3E-23 T 05-07-2017 K08M4_RS12465 558aeb3de4f1d3424328d68ada3a61ee 489 PRINTS PR00419 Adrenodoxin reductase family signature 286 300 5.3E-23 T 05-07-2017 K08M4_RS12465 558aeb3de4f1d3424328d68ada3a61ee 489 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 459 1.0E-23 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS12465 558aeb3de4f1d3424328d68ada3a61ee 489 SUPERFAMILY SSF46548 2 155 1.88E-36 T 05-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 K08M4_RS12465 558aeb3de4f1d3424328d68ada3a61ee 489 SUPERFAMILY SSF51971 389 474 3.06E-8 T 05-07-2017 K08M4_RS12465 558aeb3de4f1d3424328d68ada3a61ee 489 SUPERFAMILY SSF51971 143 407 1.41E-63 T 05-07-2017 K08M4_RS12465 558aeb3de4f1d3424328d68ada3a61ee 489 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 478 3.9E-196 T 05-07-2017 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 K08M4_RS12465 558aeb3de4f1d3424328d68ada3a61ee 489 Gene3D G3DSA:3.50.50.60 234 406 8.8E-36 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS12465 558aeb3de4f1d3424328d68ada3a61ee 489 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 38 131 2.2E-24 T 05-07-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 K08M4_RS12465 558aeb3de4f1d3424328d68ada3a61ee 489 Gene3D G3DSA:1.10.1060.10 3 147 9.0E-39 T 05-07-2017 K08M4_RS12465 558aeb3de4f1d3424328d68ada3a61ee 489 Gene3D G3DSA:3.40.50.720 407 481 2.3E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS12465 558aeb3de4f1d3424328d68ada3a61ee 489 Gene3D G3DSA:3.40.50.720 148 233 2.3E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS03000 0c99f252678eb7e871377b9dcc9fc171 560 SUPERFAMILY SSF53850 42 544 1.27E-104 T 05-07-2017 K08M4_RS03000 0c99f252678eb7e871377b9dcc9fc171 560 Gene3D G3DSA:3.90.76.10 46 196 3.1E-39 T 05-07-2017 K08M4_RS03000 0c99f252678eb7e871377b9dcc9fc171 560 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 457 6.3E-73 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain K08M4_RS03000 0c99f252678eb7e871377b9dcc9fc171 560 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 84 106 - T 05-07-2017 IPR023765 Solute-binding protein family 5, conserved site K08M4_RS03000 0c99f252678eb7e871377b9dcc9fc171 560 Gene3D G3DSA:3.10.105.10 273 515 4.8E-52 T 05-07-2017 K08M4_RS03000 0c99f252678eb7e871377b9dcc9fc171 560 PIRSF PIRSF002741 6 542 5.7E-66 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 K08M4_RS10390 873d1ec5ea28153a2b69d8bf74311c55 208 SUPERFAMILY SSF52096 23 206 7.46E-76 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS10390 873d1ec5ea28153a2b69d8bf74311c55 208 PRINTS PR00127 Clp protease catalytic subunit P signature 124 143 3.2E-54 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 K08M4_RS10390 873d1ec5ea28153a2b69d8bf74311c55 208 PRINTS PR00127 Clp protease catalytic subunit P signature 181 200 3.2E-54 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 K08M4_RS10390 873d1ec5ea28153a2b69d8bf74311c55 208 PRINTS PR00127 Clp protease catalytic subunit P signature 72 92 3.2E-54 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 K08M4_RS10390 873d1ec5ea28153a2b69d8bf74311c55 208 PRINTS PR00127 Clp protease catalytic subunit P signature 103 120 3.2E-54 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 K08M4_RS10390 873d1ec5ea28153a2b69d8bf74311c55 208 PRINTS PR00127 Clp protease catalytic subunit P signature 32 47 3.2E-54 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 K08M4_RS10390 873d1ec5ea28153a2b69d8bf74311c55 208 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 103 114 - T 05-07-2017 IPR018215 ClpP, Ser active site K08M4_RS10390 873d1ec5ea28153a2b69d8bf74311c55 208 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 125 138 - T 05-07-2017 IPR033135 ClpP, histidine active site K08M4_RS10390 873d1ec5ea28153a2b69d8bf74311c55 208 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 16 206 44.501 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 K08M4_RS10390 873d1ec5ea28153a2b69d8bf74311c55 208 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 15 205 5.7E-108 T 05-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 K08M4_RS10390 873d1ec5ea28153a2b69d8bf74311c55 208 Gene3D G3DSA:3.90.226.10 16 205 6.6E-93 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS10390 873d1ec5ea28153a2b69d8bf74311c55 208 Pfam PF00574 Clp protease 25 205 4.1E-90 T 05-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA K08M4_RS02545 1f0601bf02c38accd4219a9f59a2a51b 304 Pfam PF01551 Peptidase family M23 205 299 2.9E-31 T 05-07-2017 IPR016047 Peptidase M23 K08M4_RS02545 1f0601bf02c38accd4219a9f59a2a51b 304 Pfam PF01476 LysM domain 48 90 8.7E-10 T 05-07-2017 IPR018392 LysM domain K08M4_RS02545 1f0601bf02c38accd4219a9f59a2a51b 304 SMART SM00257 47 91 8.2E-11 T 05-07-2017 IPR018392 LysM domain K08M4_RS02545 1f0601bf02c38accd4219a9f59a2a51b 304 SUPERFAMILY SSF51261 47 303 3.77E-54 T 05-07-2017 IPR011055 Duplicated hybrid motif K08M4_RS02545 1f0601bf02c38accd4219a9f59a2a51b 304 Gene3D G3DSA:2.70.70.10 170 303 1.0E-40 T 05-07-2017 K08M4_RS02545 1f0601bf02c38accd4219a9f59a2a51b 304 Gene3D G3DSA:3.10.350.10 46 91 4.0E-14 T 05-07-2017 IPR018392 LysM domain K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 628 711 1.6E-6 T 05-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 497 593 3.3E-25 T 05-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 494 518 - T 05-07-2017 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 SUPERFAMILY SSF48179 624 716 1.62E-25 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 Gene3D G3DSA:1.10.1040.10 633 716 8.9E-21 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 Gene3D G3DSA:3.40.50.720 312 498 3.5E-56 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 Gene3D G3DSA:1.10.1040.10 499 594 4.5E-21 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 Hamap MF_01621 Fatty acid oxidation complex subunit alpha [fadB]. 1 716 52.405 T 05-07-2017 IPR012799 Fatty oxidation complex, alpha subunit FadB GO:0003857|GO:0004165|GO:0004300|GO:0008692|GO:0009062|GO:0036125|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35+5.3.3.8|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5137|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6837|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-7291|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 05-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 205 2.4E-40 T 05-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 TIGRFAM TIGR02437 FadB: fatty oxidation complex, alpha subunit FadB 1 715 0.0 T 05-07-2017 IPR012799 Fatty oxidation complex, alpha subunit FadB GO:0003857|GO:0004165|GO:0004300|GO:0008692|GO:0009062|GO:0036125|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35+5.3.3.8|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5137|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6837|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-7291|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 SUPERFAMILY SSF52096 2 304 4.67E-67 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 317 495 1.2E-57 T 05-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 Gene3D G3DSA:3.90.226.10 4 201 3.6E-57 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 Gene3D G3DSA:3.90.226.10 235 296 3.6E-57 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 SUPERFAMILY SSF51735 315 496 2.63E-55 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS00080 dd312fdd70210d40031e59a1a570ce78 723 SUPERFAMILY SSF48179 496 603 1.62E-27 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 SUPERFAMILY SSF52374 3 202 2.62E-139 T 05-07-2017 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 SUPERFAMILY SSF52374 411 662 2.62E-139 T 05-07-2017 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 Gene3D G3DSA:1.10.730.10 656 848 2.6E-41 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 Pfam PF06827 Zinc finger found in FPG and IleRS 919 946 5.1E-6 T 05-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 656 1.8E-225 T 05-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 Pfam PF08264 Anticodon-binding domain of tRNA 700 862 1.9E-26 T 05-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 2 949 21.446 T 05-07-2017 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 409 424 5.5E-32 T 05-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 576 585 5.5E-32 T 05-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 241 264 5.5E-32 T 05-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 535 548 5.5E-32 T 05-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 51 62 5.5E-32 T 05-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 SUPERFAMILY SSF47323 667 949 5.98E-74 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 69 - T 05-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 15 864 3.4E-292 T 05-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 Gene3D G3DSA:3.90.740.10 207 397 2.7E-52 T 05-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 SUPERFAMILY SSF50677 204 411 1.47E-51 T 05-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 Gene3D G3DSA:3.40.50.620 414 651 2.2E-139 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS12240 2d1a8e3b7686f16c3b38dd8264a18217 958 Gene3D G3DSA:3.40.50.620 14 200 2.2E-139 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 SUPERFAMILY SSF111369 64 123 1.57E-5 T 05-07-2017 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 Pfam PF13533 Biotin-lipoyl like 79 108 4.2E-7 T 05-07-2017 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 Pfam PF02321 Outer membrane efflux protein 170 273 9.5E-5 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 SUPERFAMILY SSF56954 171 262 1.57E-5 T 05-07-2017 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 Gene3D G3DSA:1.20.1600.10 171 261 8.2E-5 T 05-07-2017 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 Pfam PF13437 HlyD family secretion protein 316 428 1.6E-16 T 05-07-2017 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 Gene3D G3DSA:2.40.50.100 74 104 1.3E-15 T 05-07-2017 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 Gene3D G3DSA:2.40.50.100 314 349 1.3E-15 T 05-07-2017 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 ProSitePatterns PS00543 HlyD family secretion proteins signature. 428 450 - T 05-07-2017 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 386 409 1.0E-46 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 428 443 1.0E-46 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 82 102 1.0E-46 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 329 350 1.0E-46 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 443 463 1.0E-46 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 40 63 1.0E-46 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 362 386 1.0E-46 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS15155 f58fc6edfdc78e68c279ec789d20d134 463 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 31 463 3.0E-132 T 05-07-2017 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 K08M4_RS00810 962b9ec2c5678cc4d79fb6279572455a 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 05-07-2017 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS00810 962b9ec2c5678cc4d79fb6279572455a 142 Gene3D G3DSA:3.30.1550.10 2 72 1.8E-37 T 05-07-2017 IPR020784 Ribosomal protein L11, N-terminal K08M4_RS00810 962b9ec2c5678cc4d79fb6279572455a 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 3.9E-64 T 05-07-2017 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS00810 962b9ec2c5678cc4d79fb6279572455a 142 Gene3D G3DSA:1.10.10.250 73 141 7.4E-30 T 05-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 K08M4_RS00810 962b9ec2c5678cc4d79fb6279572455a 142 SUPERFAMILY SSF46906 68 141 2.49E-25 T 05-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 K08M4_RS00810 962b9ec2c5678cc4d79fb6279572455a 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 1.1E-29 T 05-07-2017 IPR020784 Ribosomal protein L11, N-terminal K08M4_RS00810 962b9ec2c5678cc4d79fb6279572455a 142 SMART SM00649 9 141 1.2E-82 T 05-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 K08M4_RS00810 962b9ec2c5678cc4d79fb6279572455a 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 1.0E-23 T 05-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 K08M4_RS00810 962b9ec2c5678cc4d79fb6279572455a 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 71 4.0E-14 T 05-07-2017 K08M4_RS00810 962b9ec2c5678cc4d79fb6279572455a 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 30.507 T 05-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 K08M4_RS00810 962b9ec2c5678cc4d79fb6279572455a 142 SUPERFAMILY SSF54747 3 73 4.84E-30 T 05-07-2017 IPR020784 Ribosomal protein L11, N-terminal K08M4_RS06740 d4efe292e9f62a620de95ac2d4df3e14 166 Gene3D G3DSA:3.90.1720.10 29 71 9.3E-4 T 05-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain K08M4_RS02540 5ae023e5c01c591f3ab6408a46d0d551 208 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 130 145 - T 05-07-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 K08M4_RS02540 5ae023e5c01c591f3ab6408a46d0d551 208 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 6 205 6.8E-72 T 05-07-2017 K08M4_RS02540 5ae023e5c01c591f3ab6408a46d0d551 208 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 1 208 38.896 T 05-07-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 K08M4_RS02540 5ae023e5c01c591f3ab6408a46d0d551 208 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 4 207 2.6E-83 T 05-07-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 K08M4_RS02540 5ae023e5c01c591f3ab6408a46d0d551 208 Gene3D G3DSA:3.40.50.150 15 205 2.7E-62 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS02540 5ae023e5c01c591f3ab6408a46d0d551 208 SUPERFAMILY SSF53335 13 205 6.44E-46 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS13100 58f504f466006fdc603bc17ad4abf51f 162 PIRSF PIRSF018472 1 162 5.7E-41 T 05-07-2017 IPR026034 Cell shape-determining protein MreD, proteobacterial type K08M4_RS13100 58f504f466006fdc603bc17ad4abf51f 162 Pfam PF04093 rod shape-determining protein MreD 9 154 3.7E-37 T 05-07-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 K08M4_RS13100 58f504f466006fdc603bc17ad4abf51f 162 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 10 154 3.6E-37 T 05-07-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 K08M4_RS07770 65425809727eb6031ee343cc8316d75c 171 Gene3D G3DSA:3.10.129.10 2 168 1.1E-58 T 05-07-2017 IPR029069 HotDog domain K08M4_RS07770 65425809727eb6031ee343cc8316d75c 171 Pfam PF07977 FabA-like domain 28 157 8.7E-55 T 05-07-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS07770 65425809727eb6031ee343cc8316d75c 171 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 2 171 49.349 T 05-07-2017 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS07770 65425809727eb6031ee343cc8316d75c 171 SUPERFAMILY SSF54637 4 168 1.7E-53 T 05-07-2017 IPR029069 HotDog domain K08M4_RS07770 65425809727eb6031ee343cc8316d75c 171 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 4 171 9.4E-90 T 05-07-2017 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS21290 02446417b9ce48f79a5b01f4f39e3213 565 Pfam PF02652 L-lactate permease 7 551 2.3E-106 T 05-07-2017 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 K08M4_RS21290 02446417b9ce48f79a5b01f4f39e3213 565 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 4 556 7.4E-104 T 05-07-2017 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 K08M4_RS13635 56cf5d8d293123b3d536fa07afef5de6 351 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 74 332 1.7E-86 T 05-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 K08M4_RS13635 56cf5d8d293123b3d536fa07afef5de6 351 Pfam PF03193 Protein of unknown function, DUF258 99 274 1.4E-56 T 05-07-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 K08M4_RS13635 56cf5d8d293123b3d536fa07afef5de6 351 Gene3D G3DSA:3.40.50.300 114 273 7.1E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13635 56cf5d8d293123b3d536fa07afef5de6 351 Gene3D G3DSA:1.10.40.50 274 342 2.3E-23 T 05-07-2017 K08M4_RS13635 56cf5d8d293123b3d536fa07afef5de6 351 SUPERFAMILY SSF52540 113 334 1.16E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13635 56cf5d8d293123b3d536fa07afef5de6 351 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 40 338 36.921 T 05-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 K08M4_RS19305 faa39c9a5cd81493c86e86fdcf5b3955 266 SUPERFAMILY SSF54506 2 264 1.92E-66 T 05-07-2017 K08M4_RS19305 faa39c9a5cd81493c86e86fdcf5b3955 266 PIRSF PIRSF016184 1 266 4.9E-49 T 05-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 K08M4_RS19305 faa39c9a5cd81493c86e86fdcf5b3955 266 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 3 266 2.0E-36 T 05-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 K08M4_RS19305 faa39c9a5cd81493c86e86fdcf5b3955 266 Gene3D G3DSA:3.10.310.10 126 254 1.5E-40 T 05-07-2017 K08M4_RS19305 faa39c9a5cd81493c86e86fdcf5b3955 266 Gene3D G3DSA:3.10.310.10 3 117 7.6E-37 T 05-07-2017 K08M4_RS19305 faa39c9a5cd81493c86e86fdcf5b3955 266 Pfam PF02567 Phenazine biosynthesis-like protein 8 262 1.2E-59 T 05-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 K08M4_RS05940 9fbf395886d0f7db842b09959732a933 294 Pfam PF03466 LysR substrate binding domain 88 288 2.6E-38 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS05940 9fbf395886d0f7db842b09959732a933 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 62 9.1E-18 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS05940 9fbf395886d0f7db842b09959732a933 294 Gene3D G3DSA:3.40.190.10 177 257 1.9E-16 T 05-07-2017 K08M4_RS05940 9fbf395886d0f7db842b09959732a933 294 SUPERFAMILY SSF53850 89 292 9.46E-41 T 05-07-2017 K08M4_RS05940 9fbf395886d0f7db842b09959732a933 294 Gene3D G3DSA:1.10.10.10 7 85 1.4E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05940 9fbf395886d0f7db842b09959732a933 294 SUPERFAMILY SSF46785 6 86 1.82E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05940 9fbf395886d0f7db842b09959732a933 294 Gene3D G3DSA:3.40.190.10 92 176 3.3E-23 T 05-07-2017 K08M4_RS21515 3dc860ac7664a708bc4aa3e1277031c2 501 PRINTS PR00163 Rubredoxin signature 482 498 1.4E-5 T 05-07-2017 IPR024935 Rubredoxin domain GO:0005506 K08M4_RS21515 3dc860ac7664a708bc4aa3e1277031c2 501 PRINTS PR00163 Rubredoxin signature 452 468 1.4E-5 T 05-07-2017 IPR024935 Rubredoxin domain GO:0005506 K08M4_RS21515 3dc860ac7664a708bc4aa3e1277031c2 501 Pfam PF00301 Rubredoxin 453 498 7.4E-18 T 05-07-2017 IPR024935 Rubredoxin domain GO:0005506 K08M4_RS21515 3dc860ac7664a708bc4aa3e1277031c2 501 Pfam PF00258 Flavodoxin 256 386 6.8E-11 T 05-07-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 K08M4_RS21515 3dc860ac7664a708bc4aa3e1277031c2 501 SMART SM00849 34 227 2.4E-25 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS21515 3dc860ac7664a708bc4aa3e1277031c2 501 SUPERFAMILY SSF56281 8 278 7.45E-49 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS21515 3dc860ac7664a708bc4aa3e1277031c2 501 Gene3D G3DSA:2.20.28.10 452 500 1.4E-19 T 05-07-2017 IPR004039 Rubredoxin-type fold K08M4_RS21515 3dc860ac7664a708bc4aa3e1277031c2 501 SUPERFAMILY SSF52218 252 396 4.35E-33 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS21515 3dc860ac7664a708bc4aa3e1277031c2 501 Pfam PF00753 Metallo-beta-lactamase superfamily 34 186 4.4E-10 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS21515 3dc860ac7664a708bc4aa3e1277031c2 501 Gene3D G3DSA:3.60.15.10 2 246 6.5E-87 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS21515 3dc860ac7664a708bc4aa3e1277031c2 501 Gene3D G3DSA:3.40.50.360 249 394 9.3E-48 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS21515 3dc860ac7664a708bc4aa3e1277031c2 501 SUPERFAMILY SSF57802 450 500 5.39E-17 T 05-07-2017 K08M4_RS08805 5cb3403a029c6ae1172ae4c6812cda95 96 Pfam PF15781 ParE-like toxin of type II bacterial toxin-antitoxin system 7 93 1.2E-36 T 05-07-2017 IPR031552 Type II bacterial toxin-antitoxin system, ParE-like toxin K08M4_RS08805 5cb3403a029c6ae1172ae4c6812cda95 96 SUPERFAMILY SSF143011 7 89 5.3E-7 T 05-07-2017 K08M4_RS10700 d8b21103e6ff36a6a19649ba108204c3 303 SUPERFAMILY SSF46894 7 109 1.81E-18 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS10700 d8b21103e6ff36a6a19649ba108204c3 303 SMART SM00862 30 107 5.7E-18 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS10700 d8b21103e6ff36a6a19649ba108204c3 303 Pfam PF00486 Transcriptional regulatory protein, C terminal 30 107 1.5E-19 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS10700 d8b21103e6ff36a6a19649ba108204c3 303 Gene3D G3DSA:1.10.10.10 13 109 1.2E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS13915 ad05846a57ce67705092683fc846d9c7 293 Gene3D G3DSA:3.40.50.720 1 195 3.8E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13915 ad05846a57ce67705092683fc846d9c7 293 Pfam PF04321 RmlD substrate binding domain 1 287 5.0E-102 T 05-07-2017 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 K08M4_RS13915 ad05846a57ce67705092683fc846d9c7 293 Gene3D G3DSA:3.90.25.10 220 282 4.0E-28 T 05-07-2017 K08M4_RS13915 ad05846a57ce67705092683fc846d9c7 293 SUPERFAMILY SSF51735 1 290 8.86E-98 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13915 ad05846a57ce67705092683fc846d9c7 293 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 287 1.7E-100 T 05-07-2017 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581 K08M4_RS14645 3fbfeee0c9a8ce98f5858d8625b96af8 672 Gene3D G3DSA:1.10.10.160 108 181 1.8E-26 T 05-07-2017 IPR013986 DExx box DNA helicase domain K08M4_RS14645 3fbfeee0c9a8ce98f5858d8625b96af8 672 Pfam PF00580 UvrD/REP helicase N-terminal domain 3 265 2.3E-75 T 05-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 K08M4_RS14645 3fbfeee0c9a8ce98f5858d8625b96af8 672 TIGRFAM TIGR01074 rep: ATP-dependent DNA helicase Rep 2 669 0.0 T 05-07-2017 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 K08M4_RS14645 3fbfeee0c9a8ce98f5858d8625b96af8 672 Pfam PF13361 UvrD-like helicase C-terminal domain 271 615 8.3E-77 T 05-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 K08M4_RS14645 3fbfeee0c9a8ce98f5858d8625b96af8 672 Gene3D G3DSA:3.40.50.300 182 279 3.0E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14645 3fbfeee0c9a8ce98f5858d8625b96af8 672 Gene3D G3DSA:3.40.50.300 2 104 3.0E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14645 3fbfeee0c9a8ce98f5858d8625b96af8 672 SUPERFAMILY SSF52540 1 641 6.1E-164 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14645 3fbfeee0c9a8ce98f5858d8625b96af8 672 Gene3D G3DSA:1.10.486.10 383 516 1.8E-40 T 05-07-2017 K08M4_RS14645 3fbfeee0c9a8ce98f5858d8625b96af8 672 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 1 670 40.83 T 05-07-2017 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 K08M4_RS14645 3fbfeee0c9a8ce98f5858d8625b96af8 672 Gene3D G3DSA:3.40.50.300 552 642 1.1E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14645 3fbfeee0c9a8ce98f5858d8625b96af8 672 Gene3D G3DSA:3.40.50.300 280 382 1.1E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17575 349f09e297ce7dd7a2def64bd6faf51e 269 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 257 3.7E-51 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS17575 349f09e297ce7dd7a2def64bd6faf51e 269 Gene3D G3DSA:3.40.190.10 113 198 3.1E-11 T 05-07-2017 K08M4_RS17575 349f09e297ce7dd7a2def64bd6faf51e 269 SMART SM00079 38 258 0.004 T 05-07-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 K08M4_RS17575 349f09e297ce7dd7a2def64bd6faf51e 269 SMART SM00062 36 259 2.8E-45 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS17575 349f09e297ce7dd7a2def64bd6faf51e 269 SUPERFAMILY SSF53850 5 256 4.79E-58 T 05-07-2017 K08M4_RS17575 349f09e297ce7dd7a2def64bd6faf51e 269 Gene3D G3DSA:3.40.190.10 33 112 3.0E-36 T 05-07-2017 K08M4_RS17575 349f09e297ce7dd7a2def64bd6faf51e 269 Gene3D G3DSA:3.40.190.10 218 257 3.0E-36 T 05-07-2017 K08M4_RS19550 4a37162fe8143b4686eb413c8c4b34ba 325 SUPERFAMILY SSF53613 9 295 1.09E-67 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS19550 4a37162fe8143b4686eb413c8c4b34ba 325 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 9 311 1.5E-99 T 05-07-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 K08M4_RS19550 4a37162fe8143b4686eb413c8c4b34ba 325 PIRSF PIRSF000535 5 314 3.2E-93 T 05-07-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 K08M4_RS19550 4a37162fe8143b4686eb413c8c4b34ba 325 Pfam PF00294 pfkB family carbohydrate kinase 29 296 2.4E-49 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB K08M4_RS19550 4a37162fe8143b4686eb413c8c4b34ba 325 Gene3D G3DSA:3.40.1190.20 42 313 9.1E-84 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS19550 4a37162fe8143b4686eb413c8c4b34ba 325 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 42 66 - T 05-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 K08M4_RS19550 4a37162fe8143b4686eb413c8c4b34ba 325 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 9 311 1.1E-100 T 05-07-2017 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 K08M4_RS19550 4a37162fe8143b4686eb413c8c4b34ba 325 Gene3D G3DSA:2.20.150.10 15 41 5.6E-4 T 05-07-2017 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395 K08M4_RS07185 68cb3f628bf9c526aea0d2d0504b2b0a 242 Pfam PF00005 ABC transporter 18 170 1.7E-35 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS07185 68cb3f628bf9c526aea0d2d0504b2b0a 242 Gene3D G3DSA:3.40.50.300 3 234 6.7E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07185 68cb3f628bf9c526aea0d2d0504b2b0a 242 PIRSF PIRSF039085 1 242 3.2E-90 T 05-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 K08M4_RS07185 68cb3f628bf9c526aea0d2d0504b2b0a 242 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS07185 68cb3f628bf9c526aea0d2d0504b2b0a 242 SUPERFAMILY SSF52540 3 236 3.69E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07185 68cb3f628bf9c526aea0d2d0504b2b0a 242 SMART SM00382 27 226 5.7E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS13430 c990714899b726c8cdd522bfb474d69d 550 Gene3D G3DSA:1.10.1390.10 503 548 1.8E-22 T 05-07-2017 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS13430 c990714899b726c8cdd522bfb474d69d 550 Pfam PF00342 Phosphoglucose isomerase 53 542 2.3E-251 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS13430 c990714899b726c8cdd522bfb474d69d 550 SUPERFAMILY SSF53697 6 547 5.56E-222 T 05-07-2017 K08M4_RS13430 c990714899b726c8cdd522bfb474d69d 550 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 498 515 - T 05-07-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS13430 c990714899b726c8cdd522bfb474d69d 550 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 266 279 - T 05-07-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS13430 c990714899b726c8cdd522bfb474d69d 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 151 170 2.4E-56 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS13430 c990714899b726c8cdd522bfb474d69d 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 466 484 2.4E-56 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS13430 c990714899b726c8cdd522bfb474d69d 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 262 280 2.4E-56 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS13430 c990714899b726c8cdd522bfb474d69d 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 498 511 2.4E-56 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS13430 c990714899b726c8cdd522bfb474d69d 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 484 498 2.4E-56 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS13430 c990714899b726c8cdd522bfb474d69d 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 339 360 2.4E-56 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS13430 c990714899b726c8cdd522bfb474d69d 550 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 47 525 42.214 T 05-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS13430 c990714899b726c8cdd522bfb474d69d 550 Gene3D G3DSA:3.40.50.10490 5 103 2.9E-177 T 05-07-2017 K08M4_RS13430 c990714899b726c8cdd522bfb474d69d 550 Gene3D G3DSA:3.40.50.10490 148 185 2.9E-177 T 05-07-2017 K08M4_RS13430 c990714899b726c8cdd522bfb474d69d 550 Gene3D G3DSA:3.40.50.10490 264 502 2.9E-177 T 05-07-2017 K08M4_RS13360 6adbaaeaaccfd67e8e19c16cfc932659 258 Gene3D G3DSA:3.40.50.620 16 221 6.4E-62 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS13360 6adbaaeaaccfd67e8e19c16cfc932659 258 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 53 224 6.2E-49 T 05-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 K08M4_RS13360 6adbaaeaaccfd67e8e19c16cfc932659 258 PIRSF PIRSF000857 5 253 3.0E-56 T 05-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 K08M4_RS13360 6adbaaeaaccfd67e8e19c16cfc932659 258 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 39 248 1.1E-83 T 05-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 K08M4_RS13360 6adbaaeaaccfd67e8e19c16cfc932659 258 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 14 248 39.064 T 05-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 K08M4_RS13360 6adbaaeaaccfd67e8e19c16cfc932659 258 SUPERFAMILY SSF52402 26 213 1.21E-53 T 05-07-2017 K08M4_RS13360 6adbaaeaaccfd67e8e19c16cfc932659 258 TIGRFAM TIGR02057 PAPS_reductase: phosphoadenosine phosphosulfate reductase 27 247 9.8E-88 T 05-07-2017 IPR011800 Phosphoadenosine phosphosulphate reductase CysH GO:0004604|GO:0019379 KEGG: 00920+1.8.4.8 K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 174 5.4E-34 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 PIRSF PIRSF000109 1 499 1.9E-172 T 05-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 199 490 5.2E-119 T 05-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 SUPERFAMILY SSF48179 197 492 8.16E-117 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 Gene3D G3DSA:1.20.5.320 458 491 3.2E-18 T 05-07-2017 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 Gene3D G3DSA:1.10.1040.10 201 456 2.0E-102 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 SMART SM01350 199 491 6.8E-192 T 05-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 378 400 6.7E-53 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 6 29 6.7E-53 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 270 297 6.7E-53 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 188 216 6.7E-53 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 76 105 6.7E-53 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 Gene3D G3DSA:3.40.50.720 4 200 8.4E-43 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 SUPERFAMILY SSF51735 7 177 3.29E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 274 286 - T 05-07-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS16945 19bc57a33c1cfbdd1c745cc3f1689e58 502 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 7 491 3.6E-172 T 05-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS00805 e1e1d6841d9e893561628e72bf6851d6 182 SMART SM00738 6 115 2.5E-49 T 05-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 K08M4_RS00805 e1e1d6841d9e893561628e72bf6851d6 182 Gene3D G3DSA:3.30.70.940 6 117 1.3E-43 T 05-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 K08M4_RS00805 e1e1d6841d9e893561628e72bf6851d6 182 SUPERFAMILY SSF50104 125 181 7.52E-20 T 05-07-2017 IPR008991 Translation protein SH3-like domain K08M4_RS00805 e1e1d6841d9e893561628e72bf6851d6 182 Gene3D G3DSA:2.30.30.30 120 181 1.9E-31 T 05-07-2017 IPR014722 Ribosomal protein L2 domain 2 K08M4_RS00805 e1e1d6841d9e893561628e72bf6851d6 182 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 6 181 25.73 T 05-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 K08M4_RS00805 e1e1d6841d9e893561628e72bf6851d6 182 SUPERFAMILY SSF82679 6 116 2.22E-39 T 05-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 K08M4_RS00805 e1e1d6841d9e893561628e72bf6851d6 182 Pfam PF02357 Transcription termination factor nusG 7 112 4.5E-26 T 05-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 K08M4_RS00805 e1e1d6841d9e893561628e72bf6851d6 182 SMART SM00739 127 154 3.2E-5 T 05-07-2017 IPR005824 KOW K08M4_RS00805 e1e1d6841d9e893561628e72bf6851d6 182 PRINTS PR00338 Transcription termination factor NUSG signature 139 154 9.4E-22 T 05-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 K08M4_RS00805 e1e1d6841d9e893561628e72bf6851d6 182 PRINTS PR00338 Transcription termination factor NUSG signature 61 73 9.4E-22 T 05-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 K08M4_RS00805 e1e1d6841d9e893561628e72bf6851d6 182 PRINTS PR00338 Transcription termination factor NUSG signature 157 173 9.4E-22 T 05-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 K08M4_RS00805 e1e1d6841d9e893561628e72bf6851d6 182 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 9 181 8.7E-71 T 05-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 K08M4_RS00805 e1e1d6841d9e893561628e72bf6851d6 182 Pfam PF00467 KOW motif 131 160 1.6E-7 T 05-07-2017 IPR005824 KOW K08M4_RS00805 e1e1d6841d9e893561628e72bf6851d6 182 ProSitePatterns PS01014 Transcription termination factor nusG signature. 164 173 - T 05-07-2017 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 Gene3D G3DSA:3.40.1360.10 245 370 4.5E-46 T 05-07-2017 K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 SMART SM00766 453 578 3.3E-55 T 05-07-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 Hamap MF_00974 DNA primase [dnaG]. 4 579 29.036 T 05-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 TIGRFAM TIGR01391 dnaG: DNA primase 5 422 5.2E-147 T 05-07-2017 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 Pfam PF01807 CHC2 zinc finger 6 101 2.4E-41 T 05-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 Gene3D G3DSA:1.20.50.20 372 429 2.1E-14 T 05-07-2017 K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 Pfam PF13155 Toprim-like 267 354 4.5E-14 T 05-07-2017 K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 Gene3D G3DSA:3.90.980.10 120 244 1.3E-45 T 05-07-2017 IPR013264 DNA primase, catalytic core, N-terminal K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 Pfam PF10410 DnaB-helicase binding domain of primase 374 429 4.3E-9 T 05-07-2017 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 SMART SM00493 263 334 4.2E-19 T 05-07-2017 IPR006171 Toprim domain K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 Gene3D G3DSA:1.10.860.10 439 582 2.1E-54 T 05-07-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 SUPERFAMILY SSF57783 4 101 2.04E-38 T 05-07-2017 K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 Pfam PF08278 DNA primase DnaG DnaB-binding 454 577 3.8E-36 T 05-07-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 Gene3D G3DSA:3.90.580.10 2 101 2.4E-42 T 05-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 Pfam PF08275 DNA primase catalytic core, N-terminal domain 130 254 3.7E-42 T 05-07-2017 IPR013264 DNA primase, catalytic core, N-terminal K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 SMART SM00400 36 90 3.0E-37 T 05-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 SUPERFAMILY SSF56731 120 429 5.23E-109 T 05-07-2017 K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 SUPERFAMILY SSF117023 450 581 3.53E-45 T 05-07-2017 K08M4_RS12830 6ac170ab88b17febe70df405f169c765 583 PIRSF PIRSF002811 2 582 6.5E-143 T 05-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 K08M4_RS15550 a9d3c7f689f2fca281cb7191d2052be6 701 ProSitePatterns PS00211 ABC transporters family signature. 593 607 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS15550 a9d3c7f689f2fca281cb7191d2052be6 701 SUPERFAMILY SSF52540 448 691 2.46E-88 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15550 a9d3c7f689f2fca281cb7191d2052be6 701 Gene3D G3DSA:3.90.70.10 55 118 1.4E-5 T 05-07-2017 K08M4_RS15550 a9d3c7f689f2fca281cb7191d2052be6 701 Gene3D G3DSA:1.20.1560.10 130 439 1.0E-75 T 05-07-2017 K08M4_RS15550 a9d3c7f689f2fca281cb7191d2052be6 701 Pfam PF00664 ABC transporter transmembrane region 144 411 1.1E-47 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS15550 a9d3c7f689f2fca281cb7191d2052be6 701 TIGRFAM TIGR01846 type_I_sec_HlyB: type I secretion system ATPase 9 692 2.8E-236 T 05-07-2017 IPR010132 ATPase, type I secretion system, HlyB GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 K08M4_RS15550 a9d3c7f689f2fca281cb7191d2052be6 701 Gene3D G3DSA:3.40.50.300 454 686 1.9E-81 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15550 a9d3c7f689f2fca281cb7191d2052be6 701 SUPERFAMILY SSF90123 130 441 3.79E-63 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS15550 a9d3c7f689f2fca281cb7191d2052be6 701 Pfam PF00005 ABC transporter 472 621 5.8E-36 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS15550 a9d3c7f689f2fca281cb7191d2052be6 701 SMART SM00382 481 667 2.5E-18 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 SUPERFAMILY SSF82866 298 495 2.09E-32 T 05-07-2017 K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 Gene3D G3DSA:3.30.2090.10 708 781 2.1E-4 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 Gene3D G3DSA:3.30.2090.10 186 271 1.7E-14 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 Gene3D G3DSA:3.30.70.1430 41 142 1.1E-19 T 05-07-2017 K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 SUPERFAMILY SSF82693 139 183 2.09E-15 T 05-07-2017 K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 SUPERFAMILY SSF82693 274 328 2.09E-15 T 05-07-2017 K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 Pfam PF00873 AcrB/AcrD/AcrF family 5 1001 1.8E-146 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 SUPERFAMILY SSF82693 550 599 8.63E-7 T 05-07-2017 K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 SUPERFAMILY SSF82714 185 271 6.15E-13 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 SUPERFAMILY SSF82866 784 1007 2.62E-43 T 05-07-2017 K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 Gene3D G3DSA:3.30.70.1430 554 596 8.5E-5 T 05-07-2017 K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 SUPERFAMILY SSF82693 41 134 8.55E-16 T 05-07-2017 K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 Gene3D G3DSA:1.10.3850.10 792 1003 1.5E-51 T 05-07-2017 K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 Gene3D G3DSA:1.10.3850.10 279 496 7.6E-40 T 05-07-2017 K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 PRINTS PR00702 Acriflavin resistance protein family signature 468 491 1.1E-21 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.1E-21 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 PRINTS PR00702 Acriflavin resistance protein family signature 390 414 1.1E-21 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.1E-21 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS07295 0041a6d7ee212306ce1f311c50fea45e 1040 SUPERFAMILY SSF82714 707 781 3.66E-6 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS00760 02e9fd57299e2cc96a053823940cbaf2 348 Pfam PF01565 FAD binding domain 22 144 1.9E-16 T 05-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 K08M4_RS00760 02e9fd57299e2cc96a053823940cbaf2 348 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 210 331 8.7E-33 T 05-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS00760 02e9fd57299e2cc96a053823940cbaf2 348 Gene3D G3DSA:3.30.43.10 8 71 4.7E-23 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 K08M4_RS00760 02e9fd57299e2cc96a053823940cbaf2 348 Gene3D G3DSA:3.30.465.10 76 233 1.4E-46 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 K08M4_RS00760 02e9fd57299e2cc96a053823940cbaf2 348 SUPERFAMILY SSF56176 8 197 1.14E-37 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 K08M4_RS00760 02e9fd57299e2cc96a053823940cbaf2 348 SUPERFAMILY SSF56194 207 341 2.22E-46 T 05-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS00760 02e9fd57299e2cc96a053823940cbaf2 348 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 333 3.0E-90 T 05-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS00760 02e9fd57299e2cc96a053823940cbaf2 348 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 348 80.906 T 05-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS00760 02e9fd57299e2cc96a053823940cbaf2 348 Gene3D G3DSA:3.90.78.10 234 342 5.8E-40 T 05-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS05205 7856319a83f068661cae0db87cf984fb 1025 Gene3D G3DSA:2.40.50.140 921 1001 1.1E-5 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS05205 7856319a83f068661cae0db87cf984fb 1025 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 5 1025 13.092 T 05-07-2017 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS05205 7856319a83f068661cae0db87cf984fb 1025 Pfam PF01336 OB-fold nucleic acid binding domain 935 1007 4.9E-8 T 05-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 K08M4_RS05205 7856319a83f068661cae0db87cf984fb 1025 SMART SM00481 6 75 4.9E-4 T 05-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 K08M4_RS05205 7856319a83f068661cae0db87cf984fb 1025 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 272 696 7.2E-147 T 05-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS05205 7856319a83f068661cae0db87cf984fb 1025 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 7 970 2.6E-162 T 05-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS05205 7856319a83f068661cae0db87cf984fb 1025 Pfam PF02811 PHP domain 10 101 1.8E-9 T 05-07-2017 IPR004013 PHP domain GO:0003824 K08M4_RS05205 7856319a83f068661cae0db87cf984fb 1025 Pfam PF14579 Helix-hairpin-helix motif 771 857 9.1E-15 T 05-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS00290 0aea03fe53b8f0dd028f057fb6f131cd 419 SMART SM00959 5 47 1.0E-15 T 05-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 K08M4_RS00290 0aea03fe53b8f0dd028f057fb6f131cd 419 SUPERFAMILY SSF50249 48 125 3.37E-28 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS00290 0aea03fe53b8f0dd028f057fb6f131cd 419 SUPERFAMILY SSF52540 90 371 1.66E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00290 0aea03fe53b8f0dd028f057fb6f131cd 419 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 251.582 T 05-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 K08M4_RS00290 0aea03fe53b8f0dd028f057fb6f131cd 419 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 2.4E-31 T 05-07-2017 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 K08M4_RS00290 0aea03fe53b8f0dd028f057fb6f131cd 419 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 4.2E-21 T 05-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS00290 0aea03fe53b8f0dd028f057fb6f131cd 419 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 2.1E-15 T 05-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 K08M4_RS00290 0aea03fe53b8f0dd028f057fb6f131cd 419 Gene3D G3DSA:3.40.50.300 132 418 3.0E-105 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00290 0aea03fe53b8f0dd028f057fb6f131cd 419 SUPERFAMILY SSF68912 1 46 1.18E-11 T 05-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 K08M4_RS00290 0aea03fe53b8f0dd028f057fb6f131cd 419 SMART SM00382 170 355 2.8E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS00290 0aea03fe53b8f0dd028f057fb6f131cd 419 Gene3D G3DSA:2.40.50.140 49 117 2.6E-35 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS00290 0aea03fe53b8f0dd028f057fb6f131cd 419 SMART SM00357 52 118 1.5E-16 T 05-07-2017 IPR011129 Cold shock protein GO:0003676 K08M4_RS00290 0aea03fe53b8f0dd028f057fb6f131cd 419 Gene3D G3DSA:1.10.720.10 1 47 6.7E-21 T 05-07-2017 K08M4_RS00290 0aea03fe53b8f0dd028f057fb6f131cd 419 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 2.8E-219 T 05-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 K08M4_RS15225 9262e42f3ba56be70b8ff2893cc857ab 160 Gene3D G3DSA:1.10.10.10 2 139 2.4E-40 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15225 9262e42f3ba56be70b8ff2893cc857ab 160 Pfam PF01047 MarR family 31 89 2.9E-15 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS15225 9262e42f3ba56be70b8ff2893cc857ab 160 SMART SM00347 24 124 4.0E-20 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS15225 9262e42f3ba56be70b8ff2893cc857ab 160 SUPERFAMILY SSF46785 3 139 7.16E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15225 9262e42f3ba56be70b8ff2893cc857ab 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 8.1E-9 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS15225 9262e42f3ba56be70b8ff2893cc857ab 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 8.1E-9 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS15225 9262e42f3ba56be70b8ff2893cc857ab 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 8.1E-9 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS05760 7f77ea6ed9474fcb5c68cf805b14bc18 377 SUPERFAMILY SSF53383 18 348 1.43E-58 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS05760 7f77ea6ed9474fcb5c68cf805b14bc18 377 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 348 4.0E-92 T 05-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 K08M4_RS05760 7f77ea6ed9474fcb5c68cf805b14bc18 377 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 207 216 - T 05-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 K08M4_RS05760 7f77ea6ed9474fcb5c68cf805b14bc18 377 Pfam PF00155 Aminotransferase class I and II 50 346 1.8E-44 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS05760 7f77ea6ed9474fcb5c68cf805b14bc18 377 Gene3D G3DSA:3.40.640.10 47 255 1.6E-60 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS05760 7f77ea6ed9474fcb5c68cf805b14bc18 377 Gene3D G3DSA:3.90.1150.10 258 350 1.5E-17 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 SUPERFAMILY SSF53720 5 430 9.02E-92 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 PRINTS PR00083 Histidinol dehydrogenase signature 167 193 4.6E-101 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 PRINTS PR00083 Histidinol dehydrogenase signature 197 222 4.6E-101 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 PRINTS PR00083 Histidinol dehydrogenase signature 229 250 4.6E-101 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 PRINTS PR00083 Histidinol dehydrogenase signature 136 162 4.6E-101 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 PRINTS PR00083 Histidinol dehydrogenase signature 319 344 4.6E-101 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 PRINTS PR00083 Histidinol dehydrogenase signature 360 378 4.6E-101 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 PRINTS PR00083 Histidinol dehydrogenase signature 35 59 4.6E-101 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 PRINTS PR00083 Histidinol dehydrogenase signature 251 270 4.6E-101 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 PIRSF PIRSF000099 1 429 1.5E-167 T 05-07-2017 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 Gene3D G3DSA:3.40.50.1980 30 237 3.4E-81 T 05-07-2017 K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 Gene3D G3DSA:3.40.50.620 238 308 3.0E-4 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 35 425 6.5E-164 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 229 261 - T 05-07-2017 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 Pfam PF00815 Histidinol dehydrogenase 28 426 2.6E-169 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 K08M4_RS09495 ebf3ae29040ae7e250d5cb0ad4775a5b 439 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 6 426 41.513 T 05-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 K08M4_RS11815 c5d97e19a0d994c512d6e10a3653c362 331 Pfam PF00990 Diguanylate cyclase, GGDEF domain 180 330 3.6E-31 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS11815 c5d97e19a0d994c512d6e10a3653c362 331 SMART SM00065 25 177 3.9E-13 T 05-07-2017 IPR003018 GAF domain GO:0005515 K08M4_RS11815 c5d97e19a0d994c512d6e10a3653c362 331 SUPERFAMILY SSF55073 185 329 3.37E-32 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS11815 c5d97e19a0d994c512d6e10a3653c362 331 Gene3D G3DSA:3.30.450.40 10 176 1.0E-21 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS11815 c5d97e19a0d994c512d6e10a3653c362 331 SMART SM00267 169 330 3.4E-28 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS11815 c5d97e19a0d994c512d6e10a3653c362 331 Pfam PF13185 GAF domain 25 168 1.2E-14 T 05-07-2017 IPR003018 GAF domain GO:0005515 K08M4_RS11815 c5d97e19a0d994c512d6e10a3653c362 331 SUPERFAMILY SSF55781 10 168 3.71E-27 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS11815 c5d97e19a0d994c512d6e10a3653c362 331 Gene3D G3DSA:3.30.70.270 182 330 1.9E-35 T 05-07-2017 K08M4_RS11815 c5d97e19a0d994c512d6e10a3653c362 331 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 177 330 4.5E-33 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS07940 0a1772100134be153732698de67a1750 397 SMART SM00359 3 87 7.3E-14 T 05-07-2017 IPR002478 PUA domain GO:0003723 K08M4_RS07940 0a1772100134be153732698de67a1750 397 Gene3D G3DSA:3.40.50.150 182 396 8.8E-56 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS07940 0a1772100134be153732698de67a1750 397 SUPERFAMILY SSF53335 78 393 2.76E-66 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS07940 0a1772100134be153732698de67a1750 397 SUPERFAMILY SSF88697 3 73 1.42E-17 T 05-07-2017 IPR015947 PUA-like domain K08M4_RS07940 0a1772100134be153732698de67a1750 397 Gene3D G3DSA:3.30.750.80 73 179 5.4E-35 T 05-07-2017 K08M4_RS07940 0a1772100134be153732698de67a1750 397 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 167 376 8.5E-28 T 05-07-2017 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 K08M4_RS07940 0a1772100134be153732698de67a1750 397 Gene3D G3DSA:2.30.130.10 3 72 2.4E-28 T 05-07-2017 IPR015947 PUA-like domain K08M4_RS04970 a3152cd432c73fe9c48df55a46e3df4a 334 SUPERFAMILY SSF52540 14 265 8.95E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04970 a3152cd432c73fe9c48df55a46e3df4a 334 Gene3D G3DSA:3.40.50.300 8 269 3.3E-80 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04970 a3152cd432c73fe9c48df55a46e3df4a 334 SMART SM00382 50 243 3.3E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS04970 a3152cd432c73fe9c48df55a46e3df4a 334 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 244 330 1.3E-25 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS04970 a3152cd432c73fe9c48df55a46e3df4a 334 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 312 2.2E-19 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS04970 a3152cd432c73fe9c48df55a46e3df4a 334 Pfam PF00005 ABC transporter 42 193 1.9E-33 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS04970 a3152cd432c73fe9c48df55a46e3df4a 334 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS03795 72d0e0a7823d7f3022e129f0845a028a 296 Gene3D G3DSA:3.30.70.890 169 285 1.5E-42 T 05-07-2017 IPR013750 GHMP kinase, C-terminal domain K08M4_RS03795 72d0e0a7823d7f3022e129f0845a028a 296 SUPERFAMILY SSF55060 167 283 3.69E-35 T 05-07-2017 IPR013750 GHMP kinase, C-terminal domain K08M4_RS03795 72d0e0a7823d7f3022e129f0845a028a 296 Pfam PF08544 GHMP kinases C terminal 202 265 1.3E-6 T 05-07-2017 IPR013750 GHMP kinase, C-terminal domain K08M4_RS03795 72d0e0a7823d7f3022e129f0845a028a 296 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 11 278 31.982 T 05-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 K08M4_RS03795 72d0e0a7823d7f3022e129f0845a028a 296 PIRSF PIRSF010376 9 286 4.6E-89 T 05-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 K08M4_RS03795 72d0e0a7823d7f3022e129f0845a028a 296 SUPERFAMILY SSF54211 11 165 7.59E-45 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS03795 72d0e0a7823d7f3022e129f0845a028a 296 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 11 285 7.4E-97 T 05-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 K08M4_RS03795 72d0e0a7823d7f3022e129f0845a028a 296 Pfam PF00288 GHMP kinases N terminal domain 94 151 4.2E-9 T 05-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 K08M4_RS03795 72d0e0a7823d7f3022e129f0845a028a 296 Gene3D G3DSA:3.30.230.10 12 166 1.7E-53 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup K08M4_RS05245 79838e26fc89865afebf5faf5192a752 166 Gene3D G3DSA:1.10.3190.10 53 166 2.2E-47 T 05-07-2017 IPR023146 YfbU, alpha-helical bundle domain K08M4_RS05245 79838e26fc89865afebf5faf5192a752 166 ProDom PD035118 UPF0304 YFBU PLASMID YPO2563/Y1624/YP2374 YBFU PM1500 OXYGEN ECA3037 VV12093 PROTEIN 1 166 1.0E-84 T 05-07-2017 IPR005587 Uncharacterised protein family UPF0304, YfbU K08M4_RS05245 79838e26fc89865afebf5faf5192a752 166 SUPERFAMILY SSF116960 1 166 1.16E-63 T 05-07-2017 K08M4_RS05245 79838e26fc89865afebf5faf5192a752 166 Pfam PF03887 YfbU domain 1 166 1.6E-69 T 05-07-2017 IPR005587 Uncharacterised protein family UPF0304, YfbU K08M4_RS05245 79838e26fc89865afebf5faf5192a752 166 Hamap MF_00762 UPF0304 protein YfbU [yfbU]. 1 166 38.09 T 05-07-2017 IPR005587 Uncharacterised protein family UPF0304, YfbU K08M4_RS05245 79838e26fc89865afebf5faf5192a752 166 Gene3D G3DSA:1.10.287.680 1 52 1.7E-29 T 05-07-2017 IPR023145 YfbU, helix-hairpin domain K08M4_RS05245 79838e26fc89865afebf5faf5192a752 166 PIRSF PIRSF006272 1 166 7.5E-78 T 05-07-2017 IPR005587 Uncharacterised protein family UPF0304, YfbU K08M4_RS10030 e50f0bf116102cecf3a312ef39673d4b 660 SUPERFAMILY SSF81345 14 331 3.01E-62 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS10030 e50f0bf116102cecf3a312ef39673d4b 660 Gene3D G3DSA:1.10.3470.10 352 660 6.6E-74 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS10030 e50f0bf116102cecf3a312ef39673d4b 660 Gene3D G3DSA:1.10.3470.10 16 333 1.4E-78 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS10030 e50f0bf116102cecf3a312ef39673d4b 660 SUPERFAMILY SSF81345 348 660 3.14E-66 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS10030 e50f0bf116102cecf3a312ef39673d4b 660 Pfam PF01032 FecCD transport family 364 660 4.1E-70 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 K08M4_RS10030 e50f0bf116102cecf3a312ef39673d4b 660 Pfam PF01032 FecCD transport family 21 331 1.2E-72 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 K08M4_RS07675 f717b061eaeb9913386349c2eb5a7f39 394 Pfam PF10442 FIST C domain 226 371 7.4E-18 T 05-07-2017 IPR019494 FIST, C-domain K08M4_RS07675 f717b061eaeb9913386349c2eb5a7f39 394 SMART SM01204 226 372 1.7E-28 T 05-07-2017 IPR019494 FIST, C-domain K08M4_RS07675 f717b061eaeb9913386349c2eb5a7f39 394 SMART SM00897 29 225 1.2E-32 T 05-07-2017 IPR013702 FIST domain, N-terminal K08M4_RS07675 f717b061eaeb9913386349c2eb5a7f39 394 Pfam PF08495 FIST N domain 33 224 5.3E-26 T 05-07-2017 IPR013702 FIST domain, N-terminal K08M4_RS00875 547164777affd4bb110750ef4c7edcd7 90 SMART SM00411 1 90 1.4E-46 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS00875 547164777affd4bb110750ef4c7edcd7 90 SUPERFAMILY SSF47729 1 90 3.24E-33 T 05-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 K08M4_RS00875 547164777affd4bb110750ef4c7edcd7 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.3E-19 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS00875 547164777affd4bb110750ef4c7edcd7 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.3E-19 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS00875 547164777affd4bb110750ef4c7edcd7 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.3E-19 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS00875 547164777affd4bb110750ef4c7edcd7 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 05-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 K08M4_RS00875 547164777affd4bb110750ef4c7edcd7 90 Gene3D G3DSA:4.10.520.10 1 90 6.5E-38 T 05-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 K08M4_RS00875 547164777affd4bb110750ef4c7edcd7 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.6E-33 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS13000 f1850d5e7cf530bdb68a3cea6ff17670 390 Pfam PF01926 50S ribosome-binding GTPase 162 284 1.5E-22 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS13000 f1850d5e7cf530bdb68a3cea6ff17670 390 Gene3D G3DSA:2.70.210.12 2 155 6.2E-56 T 05-07-2017 IPR006169 GTP1/OBG domain GO:0005525 K08M4_RS13000 f1850d5e7cf530bdb68a3cea6ff17670 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 1.3E-33 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS13000 f1850d5e7cf530bdb68a3cea6ff17670 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 1.3E-33 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS13000 f1850d5e7cf530bdb68a3cea6ff17670 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 1.3E-33 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS13000 f1850d5e7cf530bdb68a3cea6ff17670 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 1.3E-33 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS13000 f1850d5e7cf530bdb68a3cea6ff17670 390 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 05-07-2017 IPR006074 GTP1/OBG, conserved site GO:0005525 K08M4_RS13000 f1850d5e7cf530bdb68a3cea6ff17670 390 Pfam PF01018 GTP1/OBG 3 156 3.2E-56 T 05-07-2017 IPR006169 GTP1/OBG domain GO:0005525 K08M4_RS13000 f1850d5e7cf530bdb68a3cea6ff17670 390 Gene3D G3DSA:3.40.50.300 156 341 9.7E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13000 f1850d5e7cf530bdb68a3cea6ff17670 390 SUPERFAMILY SSF82051 2 157 2.49E-53 T 05-07-2017 IPR006169 GTP1/OBG domain GO:0005525 K08M4_RS13000 f1850d5e7cf530bdb68a3cea6ff17670 390 SUPERFAMILY SSF52540 151 341 7.07E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13000 f1850d5e7cf530bdb68a3cea6ff17670 390 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 332 2.5E-140 T 05-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 K08M4_RS13000 f1850d5e7cf530bdb68a3cea6ff17670 390 Hamap MF_01454 GTPase Obg [obg]. 2 333 46.617 T 05-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 K08M4_RS13000 f1850d5e7cf530bdb68a3cea6ff17670 390 PIRSF PIRSF002401 1 375 6.3E-134 T 05-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 K08M4_RS21845 d946b485f25b53cc3ddd6fa90e872775 219 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 191 7.0E-23 T 05-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 K08M4_RS21845 d946b485f25b53cc3ddd6fa90e872775 219 SUPERFAMILY SSF56784 4 213 1.8E-27 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS21845 d946b485f25b53cc3ddd6fa90e872775 219 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 5 204 7.2E-50 T 05-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial K08M4_RS21845 d946b485f25b53cc3ddd6fa90e872775 219 Gene3D G3DSA:1.20.1440.100 18 82 1.0E-18 T 05-07-2017 K08M4_RS21845 d946b485f25b53cc3ddd6fa90e872775 219 Pfam PF12710 haloacid dehalogenase-like hydrolase 7 189 5.5E-27 T 05-07-2017 K08M4_RS21845 d946b485f25b53cc3ddd6fa90e872775 219 Gene3D G3DSA:3.40.50.1000 83 218 3.0E-38 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS04260 c00877e0a7e178a19d93d826246141bb 374 Pfam PF00072 Response regulator receiver domain 5 109 1.3E-23 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS04260 c00877e0a7e178a19d93d826246141bb 374 Gene3D G3DSA:3.40.50.180 181 368 2.0E-71 T 05-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 K08M4_RS04260 c00877e0a7e178a19d93d826246141bb 374 SMART SM00448 3 126 1.6E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS04260 c00877e0a7e178a19d93d826246141bb 374 SUPERFAMILY SSF52738 183 368 5.49E-62 T 05-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 K08M4_RS04260 c00877e0a7e178a19d93d826246141bb 374 PIRSF PIRSF000876 1 372 5.9E-127 T 05-07-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 K08M4_RS04260 c00877e0a7e178a19d93d826246141bb 374 Gene3D G3DSA:3.40.50.2300 2 109 5.3E-30 T 05-07-2017 K08M4_RS04260 c00877e0a7e178a19d93d826246141bb 374 Pfam PF01339 CheB methylesterase 189 367 3.5E-57 T 05-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 K08M4_RS04260 c00877e0a7e178a19d93d826246141bb 374 SUPERFAMILY SSF52172 2 109 8.68E-27 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS04260 c00877e0a7e178a19d93d826246141bb 374 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 3 372 38.827 T 05-07-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 K08M4_RS02865 2daf3d9ff77884e37b92d9d01b0f662e 256 PIRSF PIRSF006648 7 253 2.4E-25 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 K08M4_RS02865 2daf3d9ff77884e37b92d9d01b0f662e 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 176 195 2.1E-6 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 K08M4_RS02865 2daf3d9ff77884e37b92d9d01b0f662e 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 58 80 2.1E-6 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 K08M4_RS02865 2daf3d9ff77884e37b92d9d01b0f662e 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 196 215 2.1E-6 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 K08M4_RS02865 2daf3d9ff77884e37b92d9d01b0f662e 256 Pfam PF01061 ABC-2 type transporter 8 218 2.6E-39 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 K08M4_RS15115 77307d8d15a520aab260887f4d90136f 1051 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 533 1042 6.1E-247 T 05-07-2017 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 K08M4_RS15115 77307d8d15a520aab260887f4d90136f 1051 Gene3D G3DSA:3.40.309.10 833 1024 8.8E-44 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 K08M4_RS15115 77307d8d15a520aab260887f4d90136f 1051 SUPERFAMILY SSF53720 561 1042 4.19E-126 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 K08M4_RS15115 77307d8d15a520aab260887f4d90136f 1051 SUPERFAMILY SSF51730 189 538 8.24E-111 T 05-07-2017 IPR029041 FAD-linked oxidoreductase-like K08M4_RS15115 77307d8d15a520aab260887f4d90136f 1051 Gene3D G3DSA:3.20.20.220 189 537 1.2E-104 T 05-07-2017 IPR029041 FAD-linked oxidoreductase-like K08M4_RS15115 77307d8d15a520aab260887f4d90136f 1051 Gene3D G3DSA:1.10.2060.10 68 187 8.8E-53 T 05-07-2017 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 K08M4_RS15115 77307d8d15a520aab260887f4d90136f 1051 Pfam PF01619 Proline dehydrogenase 196 496 4.8E-91 T 05-07-2017 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 K08M4_RS15115 77307d8d15a520aab260887f4d90136f 1051 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 73 186 1.8E-46 T 05-07-2017 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 K08M4_RS15115 77307d8d15a520aab260887f4d90136f 1051 Gene3D G3DSA:3.40.605.10 570 832 2.9E-74 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS15115 77307d8d15a520aab260887f4d90136f 1051 PIRSF PIRSF000197 4 1051 0.0 T 05-07-2017 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 K08M4_RS15115 77307d8d15a520aab260887f4d90136f 1051 SUPERFAMILY SSF81935 19 188 1.26E-63 T 05-07-2017 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 K08M4_RS15115 77307d8d15a520aab260887f4d90136f 1051 Pfam PF00171 Aldehyde dehydrogenase family 584 1042 4.4E-119 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS15115 77307d8d15a520aab260887f4d90136f 1051 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 845 856 - T 05-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 K08M4_RS07885 1e277511392fed9dee0e8dc71abe91a0 352 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 349 1.0E-159 T 05-07-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 K08M4_RS07885 1e277511392fed9dee0e8dc71abe91a0 352 SUPERFAMILY SSF51569 8 347 3.76E-129 T 05-07-2017 K08M4_RS07885 1e277511392fed9dee0e8dc71abe91a0 352 Gene3D G3DSA:3.20.20.70 10 350 5.6E-146 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS07885 1e277511392fed9dee0e8dc71abe91a0 352 PIRSF PIRSF001361 1 352 2.0E-156 T 05-07-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 K08M4_RS07885 1e277511392fed9dee0e8dc71abe91a0 352 Pfam PF00793 DAHP synthetase I family 42 338 2.4E-98 T 05-07-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 K08M4_RS15955 f72af11e6f67c8343e8effb14402c379 415 SUPERFAMILY SSF52266 145 341 5.66E-22 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain K08M4_RS15955 f72af11e6f67c8343e8effb14402c379 415 SUPERFAMILY SSF52266 375 407 5.66E-22 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain K08M4_RS15955 f72af11e6f67c8343e8effb14402c379 415 Pfam PF00657 GDSL-like Lipase/Acylhydrolase 146 405 1.3E-15 T 05-07-2017 IPR001087 GDSL lipase/esterase GO:0016788 K08M4_RS15955 f72af11e6f67c8343e8effb14402c379 415 Gene3D G3DSA:3.40.50.1110 139 406 5.2E-54 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain K08M4_RS07145 874cdbb9dbf6760e285f3749c718bdbf 210 SUPERFAMILY SSF51161 18 205 3.88E-46 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS07145 874cdbb9dbf6760e285f3749c718bdbf 210 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 118 146 - T 05-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 K08M4_RS07145 874cdbb9dbf6760e285f3749c718bdbf 210 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 144 1.5E-10 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS07145 874cdbb9dbf6760e285f3749c718bdbf 210 Gene3D G3DSA:2.160.10.10 20 205 1.1E-54 T 05-07-2017 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 Gene3D G3DSA:1.10.10.10 254 315 1.8E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 9 321 39.352 T 05-07-2017 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 Gene3D G3DSA:1.10.10.10 160 209 1.0E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 83 310 3.9E-35 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 Pfam PF04542 Sigma-70 region 2 87 156 6.3E-20 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 111 124 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 Pfam PF00140 Sigma-70 factor, region 1.2 49 82 4.3E-12 T 05-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 Gene3D G3DSA:1.10.601.10 18 156 2.2E-58 T 05-07-2017 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 40 321 7.4E-138 T 05-07-2017 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 Pfam PF04539 Sigma-70 region 3 167 240 1.1E-20 T 05-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 SUPERFAMILY SSF88946 48 157 9.03E-46 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 PRINTS PR00046 Major sigma-70 factor signature 135 143 2.1E-27 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 PRINTS PR00046 Major sigma-70 factor signature 295 306 2.1E-27 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 PRINTS PR00046 Major sigma-70 factor signature 111 124 2.1E-27 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 PRINTS PR00046 Major sigma-70 factor signature 259 271 2.1E-27 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 PRINTS PR00046 Major sigma-70 factor signature 280 295 2.1E-27 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 Pfam PF04545 Sigma-70, region 4 255 308 3.6E-17 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 280 306 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 SUPERFAMILY SSF88659 217 316 8.11E-23 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02550 b99507b8812dce606adf39c68efe0d4c 326 SUPERFAMILY SSF88659 160 233 1.31E-14 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS18330 8e2ed6f1d658bc5941c1c728c8a5b5e8 297 SUPERFAMILY SSF51215 35 145 1.2E-8 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 K08M4_RS18330 8e2ed6f1d658bc5941c1c728c8a5b5e8 297 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 274 1.1E-6 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS18330 8e2ed6f1d658bc5941c1c728c8a5b5e8 297 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 274 290 1.1E-6 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS18330 8e2ed6f1d658bc5941c1c728c8a5b5e8 297 Gene3D G3DSA:2.60.120.280 48 179 2.3E-9 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 K08M4_RS18330 8e2ed6f1d658bc5941c1c728c8a5b5e8 297 Gene3D G3DSA:1.10.10.60 189 243 6.9E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS18330 8e2ed6f1d658bc5941c1c728c8a5b5e8 297 Pfam PF12833 Helix-turn-helix domain 213 291 2.8E-19 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS18330 8e2ed6f1d658bc5941c1c728c8a5b5e8 297 SMART SM00342 207 290 1.1E-24 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS18330 8e2ed6f1d658bc5941c1c728c8a5b5e8 297 SUPERFAMILY SSF46689 243 294 5.38E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS18330 8e2ed6f1d658bc5941c1c728c8a5b5e8 297 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 244 286 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 K08M4_RS18330 8e2ed6f1d658bc5941c1c728c8a5b5e8 297 Gene3D G3DSA:1.10.10.60 244 294 9.2E-18 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS09200 65f2e67df621a94b97935f6a80b1d25c 189 SMART SM01185 69 124 3.3E-11 T 05-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 K08M4_RS09200 65f2e67df621a94b97935f6a80b1d25c 189 Gene3D G3DSA:2.30.30.30 1 64 8.2E-11 T 05-07-2017 IPR014722 Ribosomal protein L2 domain 2 K08M4_RS09200 65f2e67df621a94b97935f6a80b1d25c 189 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 4 62 6.3E-18 T 05-07-2017 IPR013185 Translation elongation factor, KOW-like K08M4_RS09200 65f2e67df621a94b97935f6a80b1d25c 189 Pfam PF01132 Elongation factor P (EF-P) OB domain 71 121 3.6E-11 T 05-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 K08M4_RS09200 65f2e67df621a94b97935f6a80b1d25c 189 SMART SM00841 132 187 2.4E-27 T 05-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 K08M4_RS09200 65f2e67df621a94b97935f6a80b1d25c 189 SUPERFAMILY SSF50249 67 130 1.2E-10 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09200 65f2e67df621a94b97935f6a80b1d25c 189 Gene3D G3DSA:2.40.50.140 66 130 9.9E-13 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09200 65f2e67df621a94b97935f6a80b1d25c 189 TIGRFAM TIGR02178 yeiP: elongation factor P-like protein YeiP 3 188 8.4E-85 T 05-07-2017 IPR011897 Translation elongation factor P-like, YeiP K08M4_RS09200 65f2e67df621a94b97935f6a80b1d25c 189 SUPERFAMILY SSF50249 132 188 1.22E-15 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09200 65f2e67df621a94b97935f6a80b1d25c 189 Pfam PF09285 Elongation factor P, C-terminal 132 187 3.7E-21 T 05-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 K08M4_RS09200 65f2e67df621a94b97935f6a80b1d25c 189 Gene3D G3DSA:2.40.50.140 131 188 9.5E-24 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS09200 65f2e67df621a94b97935f6a80b1d25c 189 SUPERFAMILY SSF50104 1 64 1.32E-10 T 05-07-2017 IPR008991 Translation protein SH3-like domain K08M4_RS09200 65f2e67df621a94b97935f6a80b1d25c 189 PIRSF PIRSF005901 1 189 4.8E-58 T 05-07-2017 IPR020599 Translation elongation factor P/YeiP K08M4_RS09200 65f2e67df621a94b97935f6a80b1d25c 189 ProSitePatterns PS01275 Elongation factor P signature. 153 172 - T 05-07-2017 IPR013852 Translation elongation factor P/YeiP, conserved site K08M4_RS09200 65f2e67df621a94b97935f6a80b1d25c 189 Hamap MF_00646 Elongation factor P-like protein [yeiP]. 2 188 45.906 T 05-07-2017 IPR011897 Translation elongation factor P-like, YeiP K08M4_RS20970 3f74b3bbd360d56b60bf2613c0ba534b 621 Gene3D G3DSA:3.40.50.2300 521 619 2.5E-35 T 05-07-2017 K08M4_RS20970 3f74b3bbd360d56b60bf2613c0ba534b 621 Gene3D G3DSA:3.40.930.10 1 148 5.8E-47 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS20970 3f74b3bbd360d56b60bf2613c0ba534b 621 SUPERFAMILY SSF52794 526 618 1.92E-29 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS20970 3f74b3bbd360d56b60bf2613c0ba534b 621 SUPERFAMILY SSF55804 1 147 2.35E-38 T 05-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 K08M4_RS20970 3f74b3bbd360d56b60bf2613c0ba534b 621 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 8 133 2.2E-36 T 05-07-2017 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 K08M4_RS20970 3f74b3bbd360d56b60bf2613c0ba534b 621 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 147 1.1E-33 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS20970 3f74b3bbd360d56b60bf2613c0ba534b 621 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 177 500 1.3E-78 T 05-07-2017 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 K08M4_RS20970 3f74b3bbd360d56b60bf2613c0ba534b 621 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 528 610 2.0E-28 T 05-07-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 K08M4_RS20970 3f74b3bbd360d56b60bf2613c0ba534b 621 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 528 616 9.1E-16 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS20970 3f74b3bbd360d56b60bf2613c0ba534b 621 Pfam PF02378 Phosphotransferase system, EIIC 190 447 7.4E-15 T 05-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 K08M4_RS00575 2c26f220269a0a552e627cee81f8d24d 106 Hamap MF_01009 Thiosulfate sulfurtransferase GlpE [glpE]. 2 106 32.887 T 05-07-2017 IPR023695 Thiosulfate sulfurtransferase, bacterial GO:0004792|GO:0005737 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 K08M4_RS00575 2c26f220269a0a552e627cee81f8d24d 106 SMART SM00450 7 102 2.2E-16 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS00575 2c26f220269a0a552e627cee81f8d24d 106 Gene3D G3DSA:3.40.250.10 2 104 3.4E-28 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS00575 2c26f220269a0a552e627cee81f8d24d 106 SUPERFAMILY SSF52821 1 105 1.05E-27 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS00575 2c26f220269a0a552e627cee81f8d24d 106 Pfam PF00581 Rhodanese-like domain 12 98 2.6E-10 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 Pfam PF00027 Cyclic nucleotide-binding domain 202 289 8.4E-15 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 SUPERFAMILY SSF55874 477 639 3.93E-34 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 Gene3D G3DSA:2.60.120.10 201 310 1.4E-16 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 Gene3D G3DSA:1.10.287.130 335 380 1.2E-5 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 SUPERFAMILY SSF52172 3 127 2.69E-8 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 SUPERFAMILY SSF51206 201 310 1.44E-18 T 05-07-2017 IPR018490 Cyclic nucleotide-binding-like K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 PRINTS PR00344 Bacterial sensor protein C-terminal signature 625 638 7.4E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 PRINTS PR00344 Bacterial sensor protein C-terminal signature 569 583 7.4E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 PRINTS PR00344 Bacterial sensor protein C-terminal signature 587 597 7.4E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 PRINTS PR00344 Bacterial sensor protein C-terminal signature 601 619 7.4E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 Gene3D G3DSA:3.30.565.10 463 642 1.2E-34 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 SMART SM00388 340 488 0.0063 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 Pfam PF00512 His Kinase A (phospho-acceptor) domain 340 375 3.2E-8 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 Gene3D G3DSA:3.40.50.2300 3 127 2.0E-9 T 05-07-2017 K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 531 640 8.1E-20 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 SUPERFAMILY SSF47384 335 374 1.88E-7 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS08605 76b06f56190964e3f8c81bf1432e067e 647 SMART SM00387 528 641 1.4E-24 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21700 7dca01b2b644f6ad4ae443db401653ef 922 Gene3D G3DSA:3.30.830.10 770 912 9.3E-12 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 K08M4_RS21700 7dca01b2b644f6ad4ae443db401653ef 922 SUPERFAMILY SSF63411 30 241 1.15E-41 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 K08M4_RS21700 7dca01b2b644f6ad4ae443db401653ef 922 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 64 87 - T 05-07-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 K08M4_RS21700 7dca01b2b644f6ad4ae443db401653ef 922 SUPERFAMILY SSF63411 768 912 7.33E-15 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 K08M4_RS21700 7dca01b2b644f6ad4ae443db401653ef 922 Gene3D G3DSA:3.30.830.10 24 255 3.7E-44 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 K08M4_RS21700 7dca01b2b644f6ad4ae443db401653ef 922 Gene3D G3DSA:3.30.830.10 504 726 4.7E-20 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 K08M4_RS21700 7dca01b2b644f6ad4ae443db401653ef 922 SUPERFAMILY SSF63411 504 724 1.92E-26 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 K08M4_RS21700 7dca01b2b644f6ad4ae443db401653ef 922 Pfam PF05193 Peptidase M16 inactive domain 673 852 3.8E-14 T 05-07-2017 IPR007863 Peptidase M16, C-terminal K08M4_RS21700 7dca01b2b644f6ad4ae443db401653ef 922 Pfam PF05193 Peptidase M16 inactive domain 202 372 6.8E-12 T 05-07-2017 IPR007863 Peptidase M16, C-terminal K08M4_RS21700 7dca01b2b644f6ad4ae443db401653ef 922 Pfam PF00675 Insulinase (Peptidase family M16) 52 165 4.3E-26 T 05-07-2017 IPR011765 Peptidase M16, N-terminal K08M4_RS05080 e6afd2b7ecb2df44231462ac940e6793 1038 Pfam PF10150 Ribonuclease E/G family 121 390 2.7E-94 T 05-07-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 K08M4_RS05080 e6afd2b7ecb2df44231462ac940e6793 1038 Hamap MF_00970 Ribonuclease E [rne]. 1 1026 35.905 T 05-07-2017 IPR028878 Ribonuclease E GO:0006396|GO:0008995 K08M4_RS05080 e6afd2b7ecb2df44231462ac940e6793 1038 Gene3D G3DSA:2.40.50.140 31 124 2.3E-34 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS05080 e6afd2b7ecb2df44231462ac940e6793 1038 SUPERFAMILY SSF50249 40 124 2.52E-19 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS05080 e6afd2b7ecb2df44231462ac940e6793 1038 SMART SM00316 37 119 4.0E-11 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS05080 e6afd2b7ecb2df44231462ac940e6793 1038 Pfam PF00575 S1 RNA binding domain 37 118 3.0E-14 T 05-07-2017 IPR003029 S1 domain GO:0003676 K08M4_RS05080 e6afd2b7ecb2df44231462ac940e6793 1038 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 424 4.3E-170 T 05-07-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 K08M4_RS03800 f6a6e692ca45f81b605966916f7a64b9 222 Hamap MF_00233 Outer-membrane lipoprotein LolB [lolB]. 5 220 25.441 T 05-07-2017 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 K08M4_RS03800 f6a6e692ca45f81b605966916f7a64b9 222 SUPERFAMILY SSF89392 19 220 8.63E-42 T 05-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX K08M4_RS03800 f6a6e692ca45f81b605966916f7a64b9 222 Gene3D G3DSA:2.50.20.10 13 221 3.5E-63 T 05-07-2017 K08M4_RS03800 f6a6e692ca45f81b605966916f7a64b9 222 Pfam PF03550 Outer membrane lipoprotein LolB 44 218 2.2E-42 T 05-07-2017 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 K08M4_RS03800 f6a6e692ca45f81b605966916f7a64b9 222 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 6 171 4.2E-35 T 05-07-2017 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 K08M4_RS09340 07b4e432eeda7c559287667339f78384 340 Gene3D G3DSA:1.10.8.60 177 247 1.1E-21 T 05-07-2017 K08M4_RS09340 07b4e432eeda7c559287667339f78384 340 Pfam PF00158 Sigma-54 interaction domain 5 168 1.2E-57 T 05-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 K08M4_RS09340 07b4e432eeda7c559287667339f78384 340 TIGRFAM TIGR02974 phageshock_pspF: psp operon transcriptional activator 5 331 4.4E-162 T 05-07-2017 IPR014317 Transcription activator PspF K08M4_RS09340 07b4e432eeda7c559287667339f78384 340 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 219 228 - T 05-07-2017 IPR025944 Sigma-54 interaction domain, conserved site K08M4_RS09340 07b4e432eeda7c559287667339f78384 340 SMART SM00382 25 168 3.6E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS09340 07b4e432eeda7c559287667339f78384 340 Gene3D G3DSA:1.10.10.60 284 333 9.7E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS09340 07b4e432eeda7c559287667339f78384 340 SUPERFAMILY SSF52540 5 245 3.36E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09340 07b4e432eeda7c559287667339f78384 340 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 297 314 2.5E-8 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS09340 07b4e432eeda7c559287667339f78384 340 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 314 334 2.5E-8 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS09340 07b4e432eeda7c559287667339f78384 340 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 91 106 - T 05-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 K08M4_RS09340 07b4e432eeda7c559287667339f78384 340 SUPERFAMILY SSF46689 219 333 4.44E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS09340 07b4e432eeda7c559287667339f78384 340 Pfam PF02954 Bacterial regulatory protein, Fis family 297 325 1.9E-7 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS09340 07b4e432eeda7c559287667339f78384 340 Gene3D G3DSA:3.40.50.300 3 176 5.1E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13690 4f3fb94bbf10bca4a285b59ed572c3d1 188 TIGRFAM TIGR00038 efp: translation elongation factor P 5 187 9.7E-76 T 05-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 K08M4_RS13690 4f3fb94bbf10bca4a285b59ed572c3d1 188 Pfam PF09285 Elongation factor P, C-terminal 131 186 1.1E-24 T 05-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 K08M4_RS13690 4f3fb94bbf10bca4a285b59ed572c3d1 188 SMART SM00841 131 186 8.5E-30 T 05-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 K08M4_RS13690 4f3fb94bbf10bca4a285b59ed572c3d1 188 Gene3D G3DSA:2.40.50.140 130 187 1.0E-27 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS13690 4f3fb94bbf10bca4a285b59ed572c3d1 188 Gene3D G3DSA:2.30.30.30 1 65 9.1E-29 T 05-07-2017 IPR014722 Ribosomal protein L2 domain 2 K08M4_RS13690 4f3fb94bbf10bca4a285b59ed572c3d1 188 Hamap MF_00141 Elongation factor P [efp]. 3 187 48.522 T 05-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 K08M4_RS13690 4f3fb94bbf10bca4a285b59ed572c3d1 188 SUPERFAMILY SSF50249 130 187 8.74E-18 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS13690 4f3fb94bbf10bca4a285b59ed572c3d1 188 SMART SM01185 69 123 6.0E-25 T 05-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 K08M4_RS13690 4f3fb94bbf10bca4a285b59ed572c3d1 188 PIRSF PIRSF005901 2 188 2.9E-61 T 05-07-2017 IPR020599 Translation elongation factor P/YeiP K08M4_RS13690 4f3fb94bbf10bca4a285b59ed572c3d1 188 ProSitePatterns PS01275 Elongation factor P signature. 152 171 - T 05-07-2017 IPR013852 Translation elongation factor P/YeiP, conserved site K08M4_RS13690 4f3fb94bbf10bca4a285b59ed572c3d1 188 SUPERFAMILY SSF50249 70 128 2.01E-16 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS13690 4f3fb94bbf10bca4a285b59ed572c3d1 188 Gene3D G3DSA:2.40.50.140 66 129 1.8E-24 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS13690 4f3fb94bbf10bca4a285b59ed572c3d1 188 SUPERFAMILY SSF50104 2 63 1.05E-19 T 05-07-2017 IPR008991 Translation protein SH3-like domain K08M4_RS13690 4f3fb94bbf10bca4a285b59ed572c3d1 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 62 1.4E-24 T 05-07-2017 IPR013185 Translation elongation factor, KOW-like K08M4_RS13690 4f3fb94bbf10bca4a285b59ed572c3d1 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 72 123 2.2E-21 T 05-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 Hamap MF_00020 Acetate kinase [ackA]. 1 398 186.383 T 05-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 SUPERFAMILY SSF53067 157 395 8.57E-85 T 05-07-2017 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 PRINTS PR00471 Acetate kinase family signature 172 185 7.4E-45 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 PRINTS PR00471 Acetate kinase family signature 377 389 7.4E-45 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 PRINTS PR00471 Acetate kinase family signature 298 311 7.4E-45 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 PRINTS PR00471 Acetate kinase family signature 321 337 7.4E-45 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 PRINTS PR00471 Acetate kinase family signature 5 16 7.4E-45 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 PRINTS PR00471 Acetate kinase family signature 202 223 7.4E-45 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 Gene3D G3DSA:3.30.420.40 204 395 2.8E-76 T 05-07-2017 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 Gene3D G3DSA:3.30.420.40 89 203 1.1E-7 T 05-07-2017 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 05-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 Pfam PF00871 Acetokinase family 5 390 9.2E-164 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 TIGRFAM TIGR00016 ackA: acetate kinase 2 396 4.8E-169 T 05-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 PIRSF PIRSF000722 1 397 1.9E-145 T 05-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 SUPERFAMILY SSF53067 3 195 2.01E-63 T 05-07-2017 K08M4_RS04990 cdd3896d2a04dfad485958b330400ef0 398 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 05-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS02965 dc38db3058b1f05269d4772dbe7f565a 648 SUPERFAMILY SSF55545 130 266 1.48E-20 T 05-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS02965 dc38db3058b1f05269d4772dbe7f565a 648 Gene3D G3DSA:3.20.20.80 265 645 6.1E-132 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS02965 dc38db3058b1f05269d4772dbe7f565a 648 PRINTS PR00738 Glycosyl hydrolase family 20 signature 225 245 8.4E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS02965 dc38db3058b1f05269d4772dbe7f565a 648 PRINTS PR00738 Glycosyl hydrolase family 20 signature 360 377 8.4E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS02965 dc38db3058b1f05269d4772dbe7f565a 648 PRINTS PR00738 Glycosyl hydrolase family 20 signature 431 444 8.4E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS02965 dc38db3058b1f05269d4772dbe7f565a 648 PRINTS PR00738 Glycosyl hydrolase family 20 signature 578 594 8.4E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS02965 dc38db3058b1f05269d4772dbe7f565a 648 PRINTS PR00738 Glycosyl hydrolase family 20 signature 409 427 8.4E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS02965 dc38db3058b1f05269d4772dbe7f565a 648 PRINTS PR00738 Glycosyl hydrolase family 20 signature 261 278 8.4E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS02965 dc38db3058b1f05269d4772dbe7f565a 648 PRINTS PR00738 Glycosyl hydrolase family 20 signature 290 311 8.4E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS02965 dc38db3058b1f05269d4772dbe7f565a 648 PRINTS PR00738 Glycosyl hydrolase family 20 signature 596 613 8.4E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS02965 dc38db3058b1f05269d4772dbe7f565a 648 SUPERFAMILY SSF51445 267 627 5.9E-125 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS02965 dc38db3058b1f05269d4772dbe7f565a 648 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 267 614 3.3E-119 T 05-07-2017 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 K08M4_RS02965 dc38db3058b1f05269d4772dbe7f565a 648 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 137 263 1.4E-17 T 05-07-2017 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 K08M4_RS02965 dc38db3058b1f05269d4772dbe7f565a 648 Gene3D G3DSA:3.30.379.10 133 264 7.8E-20 T 05-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS02620 e72431a8676c5ceb62eb1994bdb4e6d8 623 Pfam PF00128 Alpha amylase, catalytic domain 151 497 5.3E-61 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS02620 e72431a8676c5ceb62eb1994bdb4e6d8 623 Gene3D G3DSA:3.20.20.80 150 549 1.6E-98 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS02620 e72431a8676c5ceb62eb1994bdb4e6d8 623 Gene3D G3DSA:3.20.20.80 105 118 1.6E-98 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS02620 e72431a8676c5ceb62eb1994bdb4e6d8 623 SMART SM00642 116 535 3.5E-80 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS02620 e72431a8676c5ceb62eb1994bdb4e6d8 623 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 550 615 5.4E-6 T 05-07-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 K08M4_RS02620 e72431a8676c5ceb62eb1994bdb4e6d8 623 SUPERFAMILY SSF51011 544 620 1.01E-16 T 05-07-2017 K08M4_RS02620 e72431a8676c5ceb62eb1994bdb4e6d8 623 Gene3D G3DSA:2.60.40.1180 550 621 1.1E-19 T 05-07-2017 IPR013780 Glycosyl hydrolase, all-beta K08M4_RS02620 e72431a8676c5ceb62eb1994bdb4e6d8 623 SUPERFAMILY SSF51445 105 541 2.2E-82 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS02620 e72431a8676c5ceb62eb1994bdb4e6d8 623 SMART SM00632 547 622 1.5E-9 T 05-07-2017 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 K08M4_RS13655 fafc1de609bcf73e11ef9bfc81b53131 626 Gene3D G3DSA:1.10.287.950 379 595 5.8E-57 T 05-07-2017 K08M4_RS13655 fafc1de609bcf73e11ef9bfc81b53131 626 SMART SM00304 384 451 57.0 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS13655 fafc1de609bcf73e11ef9bfc81b53131 626 SMART SM00304 295 349 2.4E-9 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS13655 fafc1de609bcf73e11ef9bfc81b53131 626 Pfam PF02743 Cache domain 39 258 1.9E-27 T 05-07-2017 IPR033479 Double Cache domain 1 K08M4_RS13655 fafc1de609bcf73e11ef9bfc81b53131 626 SUPERFAMILY SSF103190 69 176 3.77E-9 T 05-07-2017 IPR029151 Periplasmic sensor domain-like K08M4_RS13655 fafc1de609bcf73e11ef9bfc81b53131 626 SUPERFAMILY SSF58104 317 626 1.31E-77 T 05-07-2017 K08M4_RS13655 fafc1de609bcf73e11ef9bfc81b53131 626 Pfam PF00672 HAMP domain 277 344 4.8E-11 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS13655 fafc1de609bcf73e11ef9bfc81b53131 626 SMART SM00283 364 625 2.6E-68 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS13655 fafc1de609bcf73e11ef9bfc81b53131 626 Gene3D G3DSA:3.30.450.20 136 270 8.9E-25 T 05-07-2017 K08M4_RS13655 fafc1de609bcf73e11ef9bfc81b53131 626 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 433 624 1.7E-48 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS04900 95ad09396c6dfeb1f613af7400d805fc 462 SUPERFAMILY SSF52172 12 191 2.28E-40 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS04900 95ad09396c6dfeb1f613af7400d805fc 462 SMART SM00382 167 310 4.5E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS04900 95ad09396c6dfeb1f613af7400d805fc 462 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 360 369 - T 05-07-2017 IPR025944 Sigma-54 interaction domain, conserved site K08M4_RS04900 95ad09396c6dfeb1f613af7400d805fc 462 Gene3D G3DSA:1.10.8.60 320 392 1.8E-20 T 05-07-2017 K08M4_RS04900 95ad09396c6dfeb1f613af7400d805fc 462 Pfam PF00072 Response regulator receiver domain 14 122 8.0E-24 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS04900 95ad09396c6dfeb1f613af7400d805fc 462 SUPERFAMILY SSF52540 147 390 7.05E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04900 95ad09396c6dfeb1f613af7400d805fc 462 Pfam PF00158 Sigma-54 interaction domain 148 313 2.2E-69 T 05-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 K08M4_RS04900 95ad09396c6dfeb1f613af7400d805fc 462 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 233 248 - T 05-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 K08M4_RS04900 95ad09396c6dfeb1f613af7400d805fc 462 Gene3D G3DSA:1.10.10.60 416 456 1.1E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS04900 95ad09396c6dfeb1f613af7400d805fc 462 Gene3D G3DSA:3.40.50.2300 12 135 6.1E-33 T 05-07-2017 K08M4_RS04900 95ad09396c6dfeb1f613af7400d805fc 462 SMART SM00448 11 122 2.4E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS04900 95ad09396c6dfeb1f613af7400d805fc 462 Gene3D G3DSA:3.40.50.300 144 319 2.5E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04900 95ad09396c6dfeb1f613af7400d805fc 462 SUPERFAMILY SSF46689 360 458 1.34E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS04900 95ad09396c6dfeb1f613af7400d805fc 462 Pfam PF02954 Bacterial regulatory protein, Fis family 418 456 5.6E-11 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS14890 b54e7ea1b3768b158a5f24b56d16ba4e 304 Gene3D G3DSA:1.10.10.10 6 86 1.5E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS14890 b54e7ea1b3768b158a5f24b56d16ba4e 304 SUPERFAMILY SSF46785 5 86 4.14E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS14890 b54e7ea1b3768b158a5f24b56d16ba4e 304 Gene3D G3DSA:3.40.190.10 89 171 1.0E-7 T 05-07-2017 K08M4_RS14890 b54e7ea1b3768b158a5f24b56d16ba4e 304 Gene3D G3DSA:3.40.190.10 172 255 2.1E-7 T 05-07-2017 K08M4_RS14890 b54e7ea1b3768b158a5f24b56d16ba4e 304 SUPERFAMILY SSF53850 89 290 1.45E-24 T 05-07-2017 K08M4_RS14890 b54e7ea1b3768b158a5f24b56d16ba4e 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 1.3E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS14890 b54e7ea1b3768b158a5f24b56d16ba4e 304 Pfam PF03466 LysR substrate binding domain 89 288 1.0E-21 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS16540 60133331465610da58119508c314fc92 509 Pfam PF01381 Helix-turn-helix 23 84 3.0E-8 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 K08M4_RS16540 60133331465610da58119508c314fc92 509 SUPERFAMILY SSF47413 17 90 7.04E-12 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS16540 60133331465610da58119508c314fc92 509 Pfam PF06114 Domain of unknown function (DUF955) 215 330 1.0E-4 T 05-07-2017 IPR010359 HTH domain, IrrE-type K08M4_RS16540 60133331465610da58119508c314fc92 509 SMART SM00530 22 84 1.1E-10 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 K08M4_RS16540 60133331465610da58119508c314fc92 509 Gene3D G3DSA:1.10.260.40 19 110 9.6E-19 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS16540 60133331465610da58119508c314fc92 509 Pfam PF12268 Protein of unknown function (DUF3612) 331 505 1.9E-103 T 05-07-2017 IPR022055 Protein of unknown function DUF3612 K08M4_RS11770 843c5986fd6b968b194576e518baa5e4 255 SUPERFAMILY SSF69593 5 241 1.44E-60 T 05-07-2017 K08M4_RS11770 843c5986fd6b968b194576e518baa5e4 255 Gene3D G3DSA:3.40.1130.10 46 234 3.8E-19 T 05-07-2017 K08M4_RS11770 843c5986fd6b968b194576e518baa5e4 255 SMART SM00563 67 182 3.5E-36 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 K08M4_RS11770 843c5986fd6b968b194576e518baa5e4 255 Pfam PF01553 Acyltransferase 56 179 1.2E-29 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 K08M4_RS11770 843c5986fd6b968b194576e518baa5e4 255 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 50 179 9.1E-39 T 05-07-2017 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 K08M4_RS18325 131d3cf5faa44307d6177c917f85a63e 465 PIRSF PIRSF006603 3 463 7.2E-61 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS18325 131d3cf5faa44307d6177c917f85a63e 465 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 425 2.7E-53 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS18325 131d3cf5faa44307d6177c917f85a63e 465 Pfam PF01554 MatE 252 414 2.6E-16 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS18325 131d3cf5faa44307d6177c917f85a63e 465 Pfam PF01554 MatE 28 188 2.6E-23 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS16950 cd17dadbe0e2b2a98d4cbfd28649847c 312 Gene3D G3DSA:3.40.50.880 70 302 1.5E-65 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS16950 cd17dadbe0e2b2a98d4cbfd28649847c 312 Gene3D G3DSA:3.40.630.10 4 58 5.3E-10 T 05-07-2017 K08M4_RS16950 cd17dadbe0e2b2a98d4cbfd28649847c 312 SUPERFAMILY SSF52317 74 278 7.79E-38 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS16950 cd17dadbe0e2b2a98d4cbfd28649847c 312 Pfam PF03575 Peptidase family S51 73 277 2.2E-48 T 05-07-2017 IPR005320 Peptidase S51 GO:0006508|GO:0008236 K08M4_RS08360 c17594ce6992d4a549000af7828de8ca 329 Gene3D G3DSA:1.10.260.40 3 54 5.8E-22 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS08360 c17594ce6992d4a549000af7828de8ca 329 SUPERFAMILY SSF53822 63 328 4.17E-67 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS08360 c17594ce6992d4a549000af7828de8ca 329 Gene3D G3DSA:3.40.50.2300 174 305 2.4E-43 T 05-07-2017 K08M4_RS08360 c17594ce6992d4a549000af7828de8ca 329 SUPERFAMILY SSF47413 2 60 2.57E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS08360 c17594ce6992d4a549000af7828de8ca 329 Pfam PF13377 Periplasmic binding protein-like domain 168 328 2.5E-32 T 05-07-2017 K08M4_RS08360 c17594ce6992d4a549000af7828de8ca 329 Gene3D G3DSA:3.40.50.2300 55 173 3.8E-32 T 05-07-2017 K08M4_RS08360 c17594ce6992d4a549000af7828de8ca 329 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 05-07-2017 K08M4_RS08360 c17594ce6992d4a549000af7828de8ca 329 SMART SM00354 2 72 4.0E-21 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS08360 c17594ce6992d4a549000af7828de8ca 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 7.0E-17 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS01875 f79fd69e6ed0633a66d5a4fb7f26ccfe 421 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 11 407 2.2E-122 T 05-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 K08M4_RS01875 f79fd69e6ed0633a66d5a4fb7f26ccfe 421 Gene3D G3DSA:3.65.10.10 221 416 1.2E-57 T 05-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 K08M4_RS01875 f79fd69e6ed0633a66d5a4fb7f26ccfe 421 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 416 2.2E-182 T 05-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS01875 f79fd69e6ed0633a66d5a4fb7f26ccfe 421 SUPERFAMILY SSF55205 6 418 1.01E-142 T 05-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 K08M4_RS01875 f79fd69e6ed0633a66d5a4fb7f26ccfe 421 Gene3D G3DSA:3.65.10.10 22 220 1.5E-69 T 05-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 K08M4_RS01875 f79fd69e6ed0633a66d5a4fb7f26ccfe 421 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 45.7 T 05-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS11955 33f287bb44f8625a62668c0cf2b3ed74 480 Gene3D G3DSA:2.115.10.20 39 245 8.7E-21 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain K08M4_RS11955 33f287bb44f8625a62668c0cf2b3ed74 480 SUPERFAMILY SSF49899 358 471 1.11E-11 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain K08M4_RS11955 33f287bb44f8625a62668c0cf2b3ed74 480 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 34 337 9.4E-94 T 05-07-2017 IPR013148 Glycosyl hydrolase family 32, N-terminal K08M4_RS11955 33f287bb44f8625a62668c0cf2b3ed74 480 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 34 47 - T 05-07-2017 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 K08M4_RS11955 33f287bb44f8625a62668c0cf2b3ed74 480 Gene3D G3DSA:2.60.120.560 374 473 3.3E-9 T 05-07-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal K08M4_RS11955 33f287bb44f8625a62668c0cf2b3ed74 480 SMART SM00640 34 444 3.4E-91 T 05-07-2017 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 K08M4_RS11955 33f287bb44f8625a62668c0cf2b3ed74 480 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 19 454 2.5E-127 T 05-07-2017 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 K08M4_RS11955 33f287bb44f8625a62668c0cf2b3ed74 480 SUPERFAMILY SSF75005 29 337 1.88E-95 T 05-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain K08M4_RS09745 1126c5244a578fdef2583e760b5e5ba1 324 Gene3D G3DSA:3.40.190.10 184 260 7.2E-29 T 05-07-2017 K08M4_RS09745 1126c5244a578fdef2583e760b5e5ba1 324 Gene3D G3DSA:1.10.10.10 1 81 7.8E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS09745 1126c5244a578fdef2583e760b5e5ba1 324 SUPERFAMILY SSF46785 1 113 9.07E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS09745 1126c5244a578fdef2583e760b5e5ba1 324 SUPERFAMILY SSF53850 91 322 5.16E-41 T 05-07-2017 K08M4_RS09745 1126c5244a578fdef2583e760b5e5ba1 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.8E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS09745 1126c5244a578fdef2583e760b5e5ba1 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.8E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS09745 1126c5244a578fdef2583e760b5e5ba1 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.8E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS09745 1126c5244a578fdef2583e760b5e5ba1 324 Gene3D G3DSA:3.40.190.10 91 183 2.6E-19 T 05-07-2017 K08M4_RS09745 1126c5244a578fdef2583e760b5e5ba1 324 Pfam PF03466 LysR substrate binding domain 91 292 1.4E-37 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS09745 1126c5244a578fdef2583e760b5e5ba1 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 1.2E-15 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS05830 ac80e60201c49015356d7afb42fa12c2 100 Pfam PF01910 Thiamine-binding protein 2 80 1.1E-22 T 05-07-2017 IPR002767 Thiamine-binding protein K08M4_RS05830 ac80e60201c49015356d7afb42fa12c2 100 Gene3D G3DSA:3.30.70.930 1 98 5.9E-34 T 05-07-2017 IPR029756 MTH1187/YkoF-like K08M4_RS05830 ac80e60201c49015356d7afb42fa12c2 100 SUPERFAMILY SSF89957 2 79 4.32E-20 T 05-07-2017 IPR029756 MTH1187/YkoF-like K08M4_RS10555 d0513250d6a025482508c6bd7c429157 290 Pfam PF02629 CoA binding domain 6 99 8.0E-31 T 05-07-2017 IPR003781 CoA-binding GO:0048037 K08M4_RS10555 d0513250d6a025482508c6bd7c429157 290 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 05-07-2017 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site K08M4_RS10555 d0513250d6a025482508c6bd7c429157 290 SMART SM00881 4 100 6.5E-35 T 05-07-2017 IPR003781 CoA-binding GO:0048037 K08M4_RS10555 d0513250d6a025482508c6bd7c429157 290 Gene3D G3DSA:3.40.50.720 2 119 7.6E-56 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS10555 d0513250d6a025482508c6bd7c429157 290 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 287 1.3E-145 T 05-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 K08M4_RS10555 d0513250d6a025482508c6bd7c429157 290 PIRSF PIRSF001553 1 289 9.0E-134 T 05-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 K08M4_RS10555 d0513250d6a025482508c6bd7c429157 290 SUPERFAMILY SSF52210 123 286 1.44E-55 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 K08M4_RS10555 d0513250d6a025482508c6bd7c429157 290 Gene3D G3DSA:3.40.50.261 120 287 4.4E-78 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 K08M4_RS10555 d0513250d6a025482508c6bd7c429157 290 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 05-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 K08M4_RS10555 d0513250d6a025482508c6bd7c429157 290 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 6.8E-41 T 05-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 K08M4_RS10555 d0513250d6a025482508c6bd7c429157 290 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 6.8E-41 T 05-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 K08M4_RS10555 d0513250d6a025482508c6bd7c429157 290 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 6.8E-41 T 05-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 K08M4_RS10555 d0513250d6a025482508c6bd7c429157 290 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 6.8E-41 T 05-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 K08M4_RS10555 d0513250d6a025482508c6bd7c429157 290 Pfam PF00549 CoA-ligase 151 271 1.1E-22 T 05-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 K08M4_RS10555 d0513250d6a025482508c6bd7c429157 290 SUPERFAMILY SSF51735 1 122 1.21E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS21655 165c23ab2af612fb3745223f27895ad6 311 Gene3D G3DSA:3.40.190.10 177 261 1.3E-20 T 05-07-2017 K08M4_RS21655 165c23ab2af612fb3745223f27895ad6 311 Gene3D G3DSA:3.40.190.10 92 176 5.9E-22 T 05-07-2017 K08M4_RS21655 165c23ab2af612fb3745223f27895ad6 311 SUPERFAMILY SSF46785 4 85 4.49E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21655 165c23ab2af612fb3745223f27895ad6 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 7.6E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS21655 165c23ab2af612fb3745223f27895ad6 311 Gene3D G3DSA:1.10.10.10 3 85 5.3E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21655 165c23ab2af612fb3745223f27895ad6 311 SUPERFAMILY SSF53850 89 304 2.53E-36 T 05-07-2017 K08M4_RS21655 165c23ab2af612fb3745223f27895ad6 311 Pfam PF03466 LysR substrate binding domain 89 301 3.1E-39 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS15970 601d7fe38bfd1407f063649be82e094d 547 SUPERFAMILY SSF58104 239 547 2.62E-71 T 05-07-2017 K08M4_RS15970 601d7fe38bfd1407f063649be82e094d 547 Gene3D G3DSA:1.10.287.950 301 517 2.4E-54 T 05-07-2017 K08M4_RS15970 601d7fe38bfd1407f063649be82e094d 547 Pfam PF00672 HAMP domain 200 267 3.1E-14 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS15970 601d7fe38bfd1407f063649be82e094d 547 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 333 541 1.7E-46 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS15970 601d7fe38bfd1407f063649be82e094d 547 SMART SM00283 285 546 2.3E-61 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS15970 601d7fe38bfd1407f063649be82e094d 547 SMART SM00304 218 270 4.0E-9 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS02105 0fe46f9f4d9e36698feb4cd8cb44289d 90 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 2.2E-41 T 05-07-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 K08M4_RS02105 0fe46f9f4d9e36698feb4cd8cb44289d 90 PIRSF PIRSF029827 1 90 1.2E-42 T 05-07-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 K08M4_RS02105 0fe46f9f4d9e36698feb4cd8cb44289d 90 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 76 4.0E-37 T 05-07-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 K08M4_RS02105 0fe46f9f4d9e36698feb4cd8cb44289d 90 SUPERFAMILY SSF111148 1 89 3.14E-40 T 05-07-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 K08M4_RS02105 0fe46f9f4d9e36698feb4cd8cb44289d 90 Gene3D G3DSA:1.10.3880.10 1 90 3.1E-43 T 05-07-2017 K08M4_RS02105 0fe46f9f4d9e36698feb4cd8cb44289d 90 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 27.967 T 05-07-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 K08M4_RS20420 5de2325edca188010fb4bd1501dd181d 284 Pfam PF00005 ABC transporter 21 157 2.1E-24 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS20420 5de2325edca188010fb4bd1501dd181d 284 SMART SM00382 29 207 2.0E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS20420 5de2325edca188010fb4bd1501dd181d 284 SUPERFAMILY SSF52540 4 221 2.26E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20420 5de2325edca188010fb4bd1501dd181d 284 Gene3D G3DSA:3.40.50.300 2 220 2.0E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 340 450 2.5E-32 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 Gene3D G3DSA:3.30.390.30 340 451 9.1E-41 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.0E-63 T 05-07-2017 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 2.0E-63 T 05-07-2017 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 2.0E-63 T 05-07-2017 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 418 2.0E-63 T 05-07-2017 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 425 445 2.0E-63 T 05-07-2017 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 336 357 2.0E-63 T 05-07-2017 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 2.0E-63 T 05-07-2017 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.0E-63 T 05-07-2017 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 2.0E-63 T 05-07-2017 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 SUPERFAMILY SSF51905 1 365 5.4E-59 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 05-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 Gene3D G3DSA:3.50.50.60 2 138 1.7E-46 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 319 5.7E-70 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 PIRSF PIRSF000350 1 445 4.5E-83 T 05-07-2017 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 SUPERFAMILY SSF55424 337 451 3.61E-34 T 05-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 Gene3D G3DSA:3.50.50.60 139 328 2.8E-52 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 TIGRFAM TIGR01421 gluta_reduc_1: glutathione-disulfide reductase 4 451 1.0E-212 T 05-07-2017 IPR006322 Glutathione reductase, eukaryote/bacterial GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081|Reactome: R-HSA-2408550|Reactome: R-HSA-3299685|Reactome: R-HSA-499943|Reactome: R-HSA-5628897 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 1.5E-29 T 05-07-2017 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 1.5E-29 T 05-07-2017 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.5E-29 T 05-07-2017 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 1.5E-29 T 05-07-2017 K08M4_RS14565 5dc6f76b628b643c357210cab9ba1a11 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 1.5E-29 T 05-07-2017 K08M4_RS21795 f3c4d187a4a636b4715a75d6c6b4be07 264 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 14 229 2.8E-43 T 05-07-2017 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 K08M4_RS21795 f3c4d187a4a636b4715a75d6c6b4be07 264 ProSitePatterns PS00367 Biopterin-dependent aromatic amino acid hydroxylases signature. 115 126 - T 05-07-2017 IPR018301 Aromatic amino acid hydroxylase, iron/copper binding site GO:0004497|GO:0005506|GO:0009072|GO:0055114 K08M4_RS21795 f3c4d187a4a636b4715a75d6c6b4be07 264 Gene3D G3DSA:1.10.800.10 3 236 1.4E-86 T 05-07-2017 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 K08M4_RS21795 f3c4d187a4a636b4715a75d6c6b4be07 264 SUPERFAMILY SSF56534 3 237 6.8E-93 T 05-07-2017 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 K08M4_RS21795 f3c4d187a4a636b4715a75d6c6b4be07 264 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 72 94 2.6E-8 T 05-07-2017 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 K08M4_RS21795 f3c4d187a4a636b4715a75d6c6b4be07 264 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 176 194 2.6E-8 T 05-07-2017 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 K08M4_RS21795 f3c4d187a4a636b4715a75d6c6b4be07 264 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 208 227 2.6E-8 T 05-07-2017 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 K08M4_RS21795 f3c4d187a4a636b4715a75d6c6b4be07 264 TIGRFAM TIGR01267 Phe4hydrox_mono: phenylalanine-4-hydroxylase 11 242 1.7E-93 T 05-07-2017 IPR005960 Phenylalanine-4-hydroxylase, monomeric form GO:0004505|GO:0006559|GO:0055114 KEGG: 00360+1.14.16.1|KEGG: 00400+1.14.16.1|MetaCyc: PWY-6134|MetaCyc: PWY-7158 K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 Gene3D G3DSA:2.40.30.10 301 392 2.4E-47 T 05-07-2017 K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.7E-23 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.7E-23 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.7E-23 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.7E-23 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.7E-23 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 SUPERFAMILY SSF50465 302 394 1.99E-35 T 05-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 05-07-2017 IPR031157 Tr-type G domain, conserved site K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 8.6E-58 T 05-07-2017 K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 7.3E-17 T 05-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 5.9E-14 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 393 1.4E-227 T 05-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 58.792 T 05-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 SUPERFAMILY SSF52540 6 219 1.84E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 1.9E-33 T 05-07-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 Gene3D G3DSA:2.40.30.10 210 297 3.3E-33 T 05-07-2017 K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 SUPERFAMILY SSF50447 205 301 4.52E-29 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain K08M4_RS01455 4f2285412e51c7681d15dba33028772f 394 Gene3D G3DSA:3.40.50.300 3 209 1.2E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 149 168 1.7E-65 T 05-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 257 278 1.7E-65 T 05-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 281 306 1.7E-65 T 05-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 129 149 1.7E-65 T 05-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 236 256 1.7E-65 T 05-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 110 129 1.7E-65 T 05-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 236 251 - T 05-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 112 307 4.5E-81 T 05-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 168 180 5.0E-17 T 05-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 108 117 5.0E-17 T 05-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 208 220 5.0E-17 T 05-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 297 307 5.0E-17 T 05-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 180 194 5.0E-17 T 05-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 229 241 5.0E-17 T 05-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 284 296 - T 05-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 K08M4_RS04205 7717d4912db4a927fc7bd9debaba1c29 309 Pfam PF00813 FliP family 112 303 2.0E-78 T 05-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 K08M4_RS07980 6e0979ad86bc0a2cc30ad08c0e24466a 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 235 6.8E-27 T 05-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 K08M4_RS07980 6e0979ad86bc0a2cc30ad08c0e24466a 269 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 05-07-2017 IPR000150 Cof protein GO:0016787 K08M4_RS07980 6e0979ad86bc0a2cc30ad08c0e24466a 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 262 2.7E-61 T 05-07-2017 IPR000150 Cof protein GO:0016787 K08M4_RS07980 6e0979ad86bc0a2cc30ad08c0e24466a 269 Gene3D G3DSA:3.40.50.1000 1 75 9.0E-57 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS07980 6e0979ad86bc0a2cc30ad08c0e24466a 269 Gene3D G3DSA:3.40.50.1000 181 267 9.0E-57 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS07980 6e0979ad86bc0a2cc30ad08c0e24466a 269 ProSitePatterns PS01229 Hypothetical cof family signature 2. 216 238 - T 05-07-2017 K08M4_RS07980 6e0979ad86bc0a2cc30ad08c0e24466a 269 Gene3D G3DSA:3.30.1240.10 89 180 4.0E-31 T 05-07-2017 K08M4_RS07980 6e0979ad86bc0a2cc30ad08c0e24466a 269 SUPERFAMILY SSF56784 1 266 4.8E-74 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS07980 6e0979ad86bc0a2cc30ad08c0e24466a 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 262 8.9E-66 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 Gene3D G3DSA:1.10.268.10 362 496 1.7E-48 T 05-07-2017 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 742 788 1.3E-12 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 587 637 2.4E-11 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 644 687 4.4E-8 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 537 583 1.1E-7 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 792 838 1.3E-11 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 692 736 9.1E-16 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 8 838 0.0 T 05-07-2017 K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 SUPERFAMILY SSF101904 532 853 7.72E-114 T 05-07-2017 K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 Gene3D G3DSA:3.30.1360.40 236 332 3.9E-40 T 05-07-2017 IPR024946 Arginine repressor C-terminal-like domain K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 SUPERFAMILY SSF56719 30 520 6.8E-186 T 05-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 SMART SM00434 11 498 3.1E-296 T 05-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 Gene3D G3DSA:3.90.199.10 34 216 3.7E-84 T 05-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 505 1.5E-154 T 05-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 Gene3D G3DSA:2.120.10.90 530 838 4.5E-141 T 05-07-2017 K08M4_RS09090 75caa07bc8e894d02d6189c514d5f05a 895 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 840 24.654 T 05-07-2017 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12680 2c9853bce5968bae4a68558204bcf315 367 Hamap MF_01919 Cell division protein ZapE [zapE]. 1 367 53.181 T 05-07-2017 IPR030870 Cell division protein ZapE GO:0016887|GO:0051301 K08M4_RS12680 2c9853bce5968bae4a68558204bcf315 367 SUPERFAMILY SSF52540 62 200 1.25E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12680 2c9853bce5968bae4a68558204bcf315 367 Gene3D G3DSA:3.40.50.300 12 177 6.4E-23 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12680 2c9853bce5968bae4a68558204bcf315 367 Pfam PF03969 AFG1-like ATPase 2 364 8.6E-154 T 05-07-2017 IPR005654 ATPase, AFG1-like GO:0005524 K08M4_RS11070 4ad93ac500a7c5089023a934c7d4d05c 218 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 8 197 2.7E-78 T 05-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 K08M4_RS11070 4ad93ac500a7c5089023a934c7d4d05c 218 Pfam PF00551 Formyl transferase 8 187 5.0E-62 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 K08M4_RS11070 4ad93ac500a7c5089023a934c7d4d05c 218 SUPERFAMILY SSF53328 8 205 1.7E-66 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 K08M4_RS11070 4ad93ac500a7c5089023a934c7d4d05c 218 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 9 194 31.081 T 05-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 K08M4_RS11070 4ad93ac500a7c5089023a934c7d4d05c 218 Gene3D G3DSA:3.40.50.170 7 200 4.7E-70 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 K08M4_RS11070 4ad93ac500a7c5089023a934c7d4d05c 218 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 140 163 - T 05-07-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 K08M4_RS07205 76c7f50d95149d3b6db7184c774b0b1f 285 Gene3D G3DSA:1.10.443.10 103 262 2.0E-42 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS07205 76c7f50d95149d3b6db7184c774b0b1f 285 Pfam PF00589 Phage integrase family 103 260 1.5E-33 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS07205 76c7f50d95149d3b6db7184c774b0b1f 285 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 86 5.7E-20 T 05-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 K08M4_RS07205 76c7f50d95149d3b6db7184c774b0b1f 285 SUPERFAMILY SSF56349 7 262 8.54E-46 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS07205 76c7f50d95149d3b6db7184c774b0b1f 285 Gene3D G3DSA:1.10.150.130 5 83 8.3E-5 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal K08M4_RS12875 00f76b904fa03c254d41d02f36006d35 164 Pfam PF13710 ACT domain 11 73 1.0E-17 T 05-07-2017 K08M4_RS12875 00f76b904fa03c254d41d02f36006d35 164 Pfam PF10369 Small subunit of acetolactate synthase 84 158 1.5E-25 T 05-07-2017 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 K08M4_RS12875 00f76b904fa03c254d41d02f36006d35 164 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 75 5.0E-34 T 05-07-2017 K08M4_RS12875 00f76b904fa03c254d41d02f36006d35 164 Gene3D G3DSA:3.30.70.260 1 77 6.3E-35 T 05-07-2017 K08M4_RS12875 00f76b904fa03c254d41d02f36006d35 164 SUPERFAMILY SSF55021 79 162 1.89E-26 T 05-07-2017 K08M4_RS12875 00f76b904fa03c254d41d02f36006d35 164 Gene3D G3DSA:3.30.70.1150 83 163 2.0E-28 T 05-07-2017 K08M4_RS12875 00f76b904fa03c254d41d02f36006d35 164 SUPERFAMILY SSF55021 1 75 3.31E-22 T 05-07-2017 K08M4_RS12875 00f76b904fa03c254d41d02f36006d35 164 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 159 2.8E-61 T 05-07-2017 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 Gene3D G3DSA:3.40.50.300 6 293 6.4E-106 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 Pfam PF14492 Elongation Factor G, domain II 409 482 5.0E-32 T 05-07-2017 IPR009022 Elongation factor G, III-V domain K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 SMART SM00889 485 603 1.3E-67 T 05-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 SUPERFAMILY SSF54980 608 695 2.25E-29 T 05-07-2017 IPR009022 Elongation factor G, III-V domain K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 7.3E-67 T 05-07-2017 K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 Gene3D G3DSA:3.30.230.10 489 604 1.7E-48 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 Hamap MF_00054_B Elongation factor G [fusA]. 6 697 109.058 T 05-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 Gene3D G3DSA:2.40.30.10 310 409 2.3E-37 T 05-07-2017 K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 05-07-2017 IPR031157 Tr-type G domain, conserved site K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 PRINTS PR00315 GTP-binding elongation factor signature 12 25 2.6E-17 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 PRINTS PR00315 GTP-binding elongation factor signature 101 112 2.6E-17 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 PRINTS PR00315 GTP-binding elongation factor signature 85 95 2.6E-17 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 PRINTS PR00315 GTP-binding elongation factor signature 137 146 2.6E-17 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.6E-17 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 SMART SM00838 605 693 9.4E-57 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 Gene3D G3DSA:3.30.70.870 410 485 2.6E-36 T 05-07-2017 K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 1.8E-35 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 SUPERFAMILY SSF54211 484 604 3.54E-44 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 SUPERFAMILY SSF54980 407 485 1.04E-23 T 05-07-2017 IPR009022 Elongation factor G, III-V domain K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 Pfam PF03764 Elongation factor G, domain IV 484 603 4.5E-45 T 05-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 Pfam PF03144 Elongation factor Tu domain 2 329 396 9.8E-16 T 05-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 697 0.0 T 05-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 Pfam PF00679 Elongation factor G C-terminus 605 691 4.5E-31 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 SUPERFAMILY SSF50447 271 409 3.79E-34 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 SUPERFAMILY SSF52540 6 288 2.05E-107 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01450 b7b0e16200b5b72eef29cf9c5becf427 698 Gene3D G3DSA:3.30.70.240 605 690 1.3E-32 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain K08M4_RS13390 cd9c4a25774ce1a66b8f9a6f7302ad22 333 Gene3D G3DSA:3.20.20.70 11 253 6.5E-76 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS13390 cd9c4a25774ce1a66b8f9a6f7302ad22 333 PIRSF PIRSF006621 3 332 3.2E-72 T 05-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 K08M4_RS13390 cd9c4a25774ce1a66b8f9a6f7302ad22 333 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 05-07-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 K08M4_RS13390 cd9c4a25774ce1a66b8f9a6f7302ad22 333 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 12 327 4.2E-157 T 05-07-2017 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 K08M4_RS13390 cd9c4a25774ce1a66b8f9a6f7302ad22 333 SUPERFAMILY SSF51395 12 325 1.02E-74 T 05-07-2017 K08M4_RS13390 cd9c4a25774ce1a66b8f9a6f7302ad22 333 Pfam PF01207 Dihydrouridine synthase (Dus) 16 324 4.9E-92 T 05-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 K08M4_RS13390 cd9c4a25774ce1a66b8f9a6f7302ad22 333 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 8 329 53.187 T 05-07-2017 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 K08M4_RS13820 892005bb6ad108cfdce0066a3e077381 226 SUPERFAMILY SSF56784 3 222 9.22E-36 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS13820 892005bb6ad108cfdce0066a3e077381 226 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 192 2.7E-12 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS13820 892005bb6ad108cfdce0066a3e077381 226 Gene3D G3DSA:3.40.50.1000 2 223 1.7E-32 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS13820 892005bb6ad108cfdce0066a3e077381 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 200 7.7E-23 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS13820 892005bb6ad108cfdce0066a3e077381 226 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 131 200 7.6E-8 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS17675 08002fc0647d65a757344ed39496eba0 560 Pfam PF00849 RNA pseudouridylate synthase 366 513 2.3E-28 T 05-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS17675 08002fc0647d65a757344ed39496eba0 560 SUPERFAMILY SSF55120 355 557 1.33E-56 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS17675 08002fc0647d65a757344ed39496eba0 560 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 404 418 - T 05-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 Gene3D G3DSA:1.10.287.90 28 114 1.2E-24 T 05-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 191 239 - T 05-07-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 37 255 2.6E-60 T 05-07-2017 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 284 356 1.3E-9 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 PRINTS PR01166 Cytochrome c oxidase subunit II signature 228 245 4.5E-39 T 05-07-2017 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 PRINTS PR01166 Cytochrome c oxidase subunit II signature 119 138 4.5E-39 T 05-07-2017 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 PRINTS PR01166 Cytochrome c oxidase subunit II signature 190 210 4.5E-39 T 05-07-2017 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 PRINTS PR01166 Cytochrome c oxidase subunit II signature 97 117 4.5E-39 T 05-07-2017 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 PRINTS PR01166 Cytochrome c oxidase subunit II signature 166 187 4.5E-39 T 05-07-2017 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 PRINTS PR01166 Cytochrome c oxidase subunit II signature 210 227 4.5E-39 T 05-07-2017 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 PRINTS PR01166 Cytochrome c oxidase subunit II signature 85 97 4.5E-39 T 05-07-2017 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 123 245 2.1E-36 T 05-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 Gene3D G3DSA:2.60.40.420 115 297 3.4E-58 T 05-07-2017 IPR008972 Cupredoxin K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 Gene3D G3DSA:1.10.760.10 298 383 5.8E-26 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 SUPERFAMILY SSF46626 225 367 9.6E-25 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 SUPERFAMILY SSF81464 27 117 2.29E-25 T 05-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 29 108 1.9E-14 T 05-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16720 39602627cbf2ea777c10f463234d80d8 419 SUPERFAMILY SSF49503 121 260 4.08E-53 T 05-07-2017 IPR008972 Cupredoxin K08M4_RS08255 5ee4845a1263151298f3fc445a1eb9b6 210 SUPERFAMILY SSF52833 1 80 1.1E-16 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS08255 5ee4845a1263151298f3fc445a1eb9b6 210 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 77 2.5E-15 T 05-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 K08M4_RS08255 5ee4845a1263151298f3fc445a1eb9b6 210 Gene3D G3DSA:3.40.30.10 1 89 2.1E-17 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS02715 e4c69ce6f64eeb2c67b3324e06503c98 952 SUPERFAMILY SSF63411 51 266 1.47E-56 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 K08M4_RS02715 e4c69ce6f64eeb2c67b3324e06503c98 952 Gene3D G3DSA:3.30.830.10 746 930 2.1E-22 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 K08M4_RS02715 e4c69ce6f64eeb2c67b3324e06503c98 952 SUPERFAMILY SSF63411 520 722 3.03E-43 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 K08M4_RS02715 e4c69ce6f64eeb2c67b3324e06503c98 952 SUPERFAMILY SSF63411 743 942 3.19E-36 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 K08M4_RS02715 e4c69ce6f64eeb2c67b3324e06503c98 952 Gene3D G3DSA:3.30.830.10 285 463 7.6E-19 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 K08M4_RS02715 e4c69ce6f64eeb2c67b3324e06503c98 952 SUPERFAMILY SSF63411 281 469 2.83E-29 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 K08M4_RS02715 e4c69ce6f64eeb2c67b3324e06503c98 952 Gene3D G3DSA:3.30.830.10 51 268 2.0E-57 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 K08M4_RS02715 e4c69ce6f64eeb2c67b3324e06503c98 952 Gene3D G3DSA:3.30.830.10 522 731 1.0E-48 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 K08M4_RS02715 e4c69ce6f64eeb2c67b3324e06503c98 952 Pfam PF05193 Peptidase M16 inactive domain 220 393 1.3E-25 T 05-07-2017 IPR007863 Peptidase M16, C-terminal K08M4_RS02715 e4c69ce6f64eeb2c67b3324e06503c98 952 Pfam PF05193 Peptidase M16 inactive domain 686 858 3.0E-23 T 05-07-2017 IPR007863 Peptidase M16, C-terminal K08M4_RS02715 e4c69ce6f64eeb2c67b3324e06503c98 952 Pfam PF00675 Insulinase (Peptidase family M16) 64 181 1.1E-17 T 05-07-2017 IPR011765 Peptidase M16, N-terminal K08M4_RS02715 e4c69ce6f64eeb2c67b3324e06503c98 952 Pfam PF00675 Insulinase (Peptidase family M16) 541 655 2.0E-13 T 05-07-2017 IPR011765 Peptidase M16, N-terminal K08M4_RS20980 cab389dae50e2b5ee5bab5c401e138fa 257 SUPERFAMILY SSF55594 16 89 2.22E-11 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS20980 cab389dae50e2b5ee5bab5c401e138fa 257 SUPERFAMILY SSF55804 121 249 9.81E-20 T 05-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 K08M4_RS20980 cab389dae50e2b5ee5bab5c401e138fa 257 Gene3D G3DSA:3.40.930.10 131 253 3.0E-21 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS20980 cab389dae50e2b5ee5bab5c401e138fa 257 PIRSF PIRSF029195 1 257 5.2E-137 T 05-07-2017 IPR016910 Uncharacterised conserved protein UCP029195, PTS-EIIA 2 K08M4_RS20980 cab389dae50e2b5ee5bab5c401e138fa 257 Gene3D G3DSA:3.30.1340.10 20 86 8.8E-9 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS20980 cab389dae50e2b5ee5bab5c401e138fa 257 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 128 251 8.5E-22 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS05260 6e80a34ab23ad1cebfec2695e600c001 758 Pfam PF01228 Glycine radical 628 739 1.3E-43 T 05-07-2017 IPR001150 Glycine radical domain GO:0003824|GO:0008152 K08M4_RS05260 6e80a34ab23ad1cebfec2695e600c001 758 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 8 758 0.0 T 05-07-2017 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 K08M4_RS05260 6e80a34ab23ad1cebfec2695e600c001 758 Pfam PF02901 Pyruvate formate lyase-like 21 612 3.7E-202 T 05-07-2017 IPR004184 Pyruvate formate lyase domain GO:0003824 K08M4_RS05260 6e80a34ab23ad1cebfec2695e600c001 758 SUPERFAMILY SSF51998 4 757 1.95E-287 T 05-07-2017 K08M4_RS05260 6e80a34ab23ad1cebfec2695e600c001 758 PIRSF PIRSF000379 5 758 0.0 T 05-07-2017 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 K08M4_RS05260 6e80a34ab23ad1cebfec2695e600c001 758 Gene3D G3DSA:3.20.70.20 3 757 0.0 T 05-07-2017 K08M4_RS05260 6e80a34ab23ad1cebfec2695e600c001 758 ProSitePatterns PS00850 Glycine radical domain signature. 728 736 - T 05-07-2017 IPR019777 Formate C-acetyltransferase glycine radical, conserved site K08M4_RS14405 f0c905f5b127cf2f6976fcc85d22aea7 544 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 6 446 1.3E-176 T 05-07-2017 IPR010232 Probable protein kinase UbiB GO:0006744 K08M4_RS14405 f0c905f5b127cf2f6976fcc85d22aea7 544 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 3 539 55.888 T 05-07-2017 IPR010232 Probable protein kinase UbiB GO:0006744 K08M4_RS14405 f0c905f5b127cf2f6976fcc85d22aea7 544 Gene3D G3DSA:3.90.1200.10 238 298 5.5E-4 T 05-07-2017 K08M4_RS14405 f0c905f5b127cf2f6976fcc85d22aea7 544 Pfam PF03109 ABC1 family 112 230 4.1E-35 T 05-07-2017 IPR004147 UbiB domain K08M4_RS14405 f0c905f5b127cf2f6976fcc85d22aea7 544 SUPERFAMILY SSF56112 94 158 3.1E-44 T 05-07-2017 IPR011009 Protein kinase-like domain K08M4_RS14405 f0c905f5b127cf2f6976fcc85d22aea7 544 SUPERFAMILY SSF56112 193 436 3.1E-44 T 05-07-2017 IPR011009 Protein kinase-like domain K08M4_RS02460 885408cb71a7a805b8cee0870858ee4f 323 Gene3D G3DSA:3.30.300.20 215 316 5.7E-39 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta K08M4_RS02460 885408cb71a7a805b8cee0870858ee4f 323 Pfam PF01926 50S ribosome-binding GTPase 32 146 2.4E-23 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS02460 885408cb71a7a805b8cee0870858ee4f 323 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 29 191 3.6E-39 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 K08M4_RS02460 885408cb71a7a805b8cee0870858ee4f 323 Pfam PF07650 KH domain 230 307 5.7E-20 T 05-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS02460 885408cb71a7a805b8cee0870858ee4f 323 TIGRFAM TIGR00436 era: GTP-binding protein Era 30 302 2.7E-110 T 05-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 K08M4_RS02460 885408cb71a7a805b8cee0870858ee4f 323 Gene3D G3DSA:3.40.50.300 28 214 5.4E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02460 885408cb71a7a805b8cee0870858ee4f 323 SUPERFAMILY SSF52540 32 227 1.72E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02460 885408cb71a7a805b8cee0870858ee4f 323 Hamap MF_00367 GTPase Era [era]. 27 319 35.508 T 05-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 K08M4_RS02460 885408cb71a7a805b8cee0870858ee4f 323 SUPERFAMILY SSF54814 203 319 6.54E-41 T 05-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 K08M4_RS01670 d42738cb4e9a2272ddd25b91b14ceb07 476 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 82 97 - T 05-07-2017 IPR031157 Tr-type G domain, conserved site K08M4_RS01670 d42738cb4e9a2272ddd25b91b14ceb07 476 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 27 433 7.7E-196 T 05-07-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 K08M4_RS01670 d42738cb4e9a2272ddd25b91b14ceb07 476 PRINTS PR00315 GTP-binding elongation factor signature 125 136 5.9E-13 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS01670 d42738cb4e9a2272ddd25b91b14ceb07 476 PRINTS PR00315 GTP-binding elongation factor signature 109 119 5.9E-13 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS01670 d42738cb4e9a2272ddd25b91b14ceb07 476 PRINTS PR00315 GTP-binding elongation factor signature 162 171 5.9E-13 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS01670 d42738cb4e9a2272ddd25b91b14ceb07 476 PRINTS PR00315 GTP-binding elongation factor signature 89 97 5.9E-13 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS01670 d42738cb4e9a2272ddd25b91b14ceb07 476 PRINTS PR00315 GTP-binding elongation factor signature 28 41 5.9E-13 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS01670 d42738cb4e9a2272ddd25b91b14ceb07 476 Gene3D G3DSA:2.40.30.10 243 359 3.5E-20 T 05-07-2017 K08M4_RS01670 d42738cb4e9a2272ddd25b91b14ceb07 476 Gene3D G3DSA:3.40.50.300 19 234 2.4E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01670 d42738cb4e9a2272ddd25b91b14ceb07 476 SUPERFAMILY SSF50465 333 434 1.01E-27 T 05-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal K08M4_RS01670 d42738cb4e9a2272ddd25b91b14ceb07 476 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 18 474 52.883 T 05-07-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 K08M4_RS01670 d42738cb4e9a2272ddd25b91b14ceb07 476 Pfam PF00009 Elongation factor Tu GTP binding domain 25 226 4.5E-45 T 05-07-2017 K08M4_RS01670 d42738cb4e9a2272ddd25b91b14ceb07 476 SUPERFAMILY SSF50447 243 324 7.51E-24 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain K08M4_RS01670 d42738cb4e9a2272ddd25b91b14ceb07 476 SUPERFAMILY SSF52540 19 236 1.29E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01670 d42738cb4e9a2272ddd25b91b14ceb07 476 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 33 210 9.7E-14 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 SUPERFAMILY SSF52096 21 326 4.09E-65 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 SUPERFAMILY SSF51735 333 515 1.21E-46 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 TIGRFAM TIGR02440 FadJ: fatty oxidation complex, alpha subunit FadJ 21 726 0.0 T 05-07-2017 IPR012802 Fatty oxidation complex, alpha subunit FadJ GO:0003857|GO:0004300|GO:0006635|GO:0008692|GO:0051287|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 Gene3D G3DSA:3.40.50.720 328 518 2.2E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 517 610 1.4E-23 T 05-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 638 712 4.1E-6 T 05-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 336 515 1.2E-52 T 05-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 Gene3D G3DSA:1.10.1040.10 519 611 6.9E-25 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 SUPERFAMILY SSF48179 517 616 7.23E-26 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 Pfam PF00378 Enoyl-CoA hydratase/isomerase 34 265 1.9E-37 T 05-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 Gene3D G3DSA:3.90.226.10 16 228 2.2E-60 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 Hamap MF_01617 Fatty acid oxidation complex subunit alpha [fadJ]. 16 726 52.101 T 05-07-2017 IPR012802 Fatty oxidation complex, alpha subunit FadJ GO:0003857|GO:0004300|GO:0006635|GO:0008692|GO:0051287|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 121 141 - T 05-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 SUPERFAMILY SSF48179 633 727 5.19E-26 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 514 539 - T 05-07-2017 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 K08M4_RS04360 43b12e66db27001b43b9e7516f07f416 727 Gene3D G3DSA:1.10.1040.10 644 717 2.0E-21 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 K08M4_RS14180 a5c8c1dccd099a949a7828e2fe8bfc44 194 Pfam PF01521 Iron-sulphur cluster biosynthesis 3 100 5.4E-13 T 05-07-2017 IPR000361 FeS cluster biogenesis K08M4_RS14180 a5c8c1dccd099a949a7828e2fe8bfc44 194 Pfam PF01106 NifU-like domain 113 179 6.5E-19 T 05-07-2017 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 K08M4_RS14180 a5c8c1dccd099a949a7828e2fe8bfc44 194 SUPERFAMILY SSF117916 97 186 8.72E-22 T 05-07-2017 K08M4_RS14180 a5c8c1dccd099a949a7828e2fe8bfc44 194 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 121 180 5.0E-25 T 05-07-2017 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 K08M4_RS14180 a5c8c1dccd099a949a7828e2fe8bfc44 194 Gene3D G3DSA:2.60.300.12 3 99 2.3E-19 T 05-07-2017 IPR000361 FeS cluster biogenesis K08M4_RS14180 a5c8c1dccd099a949a7828e2fe8bfc44 194 SUPERFAMILY SSF89360 3 99 4.12E-22 T 05-07-2017 IPR000361 FeS cluster biogenesis K08M4_RS14180 a5c8c1dccd099a949a7828e2fe8bfc44 194 Hamap MF_01637 Fe/S biogenesis protein NfuA [nfuA]. 3 194 44.147 T 05-07-2017 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 K08M4_RS14180 a5c8c1dccd099a949a7828e2fe8bfc44 194 TIGRFAM TIGR03341 YhgI_GntY: IscR-regulated protein YhgI 4 194 1.1E-95 T 05-07-2017 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 K08M4_RS10425 c3f11f0e6b2a8e1a708fb3b036c1d6fc 135 Gene3D G3DSA:3.10.129.10 2 130 9.3E-29 T 05-07-2017 IPR029069 HotDog domain K08M4_RS10425 c3f11f0e6b2a8e1a708fb3b036c1d6fc 135 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 10 27 - T 05-07-2017 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 K08M4_RS10425 c3f11f0e6b2a8e1a708fb3b036c1d6fc 135 Pfam PF13279 Thioesterase-like superfamily 14 130 5.7E-7 T 05-07-2017 K08M4_RS10425 c3f11f0e6b2a8e1a708fb3b036c1d6fc 135 PIRSF PIRSF003230 1 134 4.4E-34 T 05-07-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 K08M4_RS10425 c3f11f0e6b2a8e1a708fb3b036c1d6fc 135 SUPERFAMILY SSF54637 4 130 7.78E-24 T 05-07-2017 IPR029069 HotDog domain K08M4_RS02695 60b155663e99187aae002680ef6fd443 593 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 549 566 - T 05-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 K08M4_RS02695 60b155663e99187aae002680ef6fd443 593 SUPERFAMILY SSF51569 1 300 3.48E-88 T 05-07-2017 K08M4_RS02695 60b155663e99187aae002680ef6fd443 593 Gene3D G3DSA:3.20.20.70 2 282 7.1E-116 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS02695 60b155663e99187aae002680ef6fd443 593 Gene3D G3DSA:2.40.50.100 522 592 4.3E-23 T 05-07-2017 K08M4_RS02695 60b155663e99187aae002680ef6fd443 593 SUPERFAMILY SSF89000 297 462 5.1E-53 T 05-07-2017 K08M4_RS02695 60b155663e99187aae002680ef6fd443 593 Pfam PF02436 Conserved carboxylase domain 292 492 2.9E-60 T 05-07-2017 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 K08M4_RS02695 60b155663e99187aae002680ef6fd443 593 Pfam PF00364 Biotin-requiring enzyme 527 591 7.6E-16 T 05-07-2017 IPR000089 Biotin/lipoyl attachment K08M4_RS02695 60b155663e99187aae002680ef6fd443 593 Pfam PF00682 HMGL-like 6 270 7.9E-58 T 05-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 K08M4_RS02695 60b155663e99187aae002680ef6fd443 593 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 7 587 1.6E-266 T 05-07-2017 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 K08M4_RS02695 60b155663e99187aae002680ef6fd443 593 SUPERFAMILY SSF51230 518 592 8.51E-20 T 05-07-2017 IPR011053 Single hybrid motif K08M4_RS07195 0aeed04bbbfbb3b7dfc19171cc8bce17 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 216 4.6E-21 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07195 0aeed04bbbfbb3b7dfc19171cc8bce17 228 SUPERFAMILY SSF161098 10 202 1.31E-38 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07195 0aeed04bbbfbb3b7dfc19171cc8bce17 228 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 111 1.0E-16 T 05-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 K08M4_RS07195 0aeed04bbbfbb3b7dfc19171cc8bce17 228 Gene3D G3DSA:1.10.3720.10 10 215 1.3E-41 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS04565 b23e143daa148fda19faaab6276e46eb 420 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 144 159 - T 05-07-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 K08M4_RS04565 b23e143daa148fda19faaab6276e46eb 420 SUPERFAMILY SSF53623 12 285 2.62E-84 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS04565 b23e143daa148fda19faaab6276e46eb 420 SUPERFAMILY SSF53244 286 416 1.39E-31 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS04565 b23e143daa148fda19faaab6276e46eb 420 TIGRFAM TIGR01499 folC: bifunctional protein FolC 32 414 2.2E-102 T 05-07-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 K08M4_RS04565 b23e143daa148fda19faaab6276e46eb 420 Gene3D G3DSA:3.40.1190.10 12 287 7.9E-86 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS04565 b23e143daa148fda19faaab6276e46eb 420 Pfam PF02875 Mur ligase family, glutamate ligase domain 287 334 2.7E-6 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS04565 b23e143daa148fda19faaab6276e46eb 420 PIRSF PIRSF001563 7 420 2.4E-104 T 05-07-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 K08M4_RS04565 b23e143daa148fda19faaab6276e46eb 420 Pfam PF08245 Mur ligase middle domain 54 194 2.0E-7 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS04565 b23e143daa148fda19faaab6276e46eb 420 Gene3D G3DSA:3.90.190.20 288 417 1.7E-40 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS02565 6eac02c7d355d05f07b93ddf2e94ebc4 346 SUPERFAMILY SSF52540 4 267 4.87E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02565 6eac02c7d355d05f07b93ddf2e94ebc4 346 Gene3D G3DSA:3.30.250.10 268 326 1.2E-27 T 05-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal K08M4_RS02565 6eac02c7d355d05f07b93ddf2e94ebc4 346 Hamap MF_00268 Protein RecA [recA]. 5 329 50.482 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 K08M4_RS02565 6eac02c7d355d05f07b93ddf2e94ebc4 346 Pfam PF00154 recA bacterial DNA recombination protein 7 267 6.8E-142 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 K08M4_RS02565 6eac02c7d355d05f07b93ddf2e94ebc4 346 SMART SM00382 57 228 4.7E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS02565 6eac02c7d355d05f07b93ddf2e94ebc4 346 PRINTS PR00142 RecA protein signature 210 238 7.4E-85 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 K08M4_RS02565 6eac02c7d355d05f07b93ddf2e94ebc4 346 PRINTS PR00142 RecA protein signature 243 272 7.4E-85 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 K08M4_RS02565 6eac02c7d355d05f07b93ddf2e94ebc4 346 PRINTS PR00142 RecA protein signature 165 194 7.4E-85 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 K08M4_RS02565 6eac02c7d355d05f07b93ddf2e94ebc4 346 PRINTS PR00142 RecA protein signature 93 122 7.4E-85 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 K08M4_RS02565 6eac02c7d355d05f07b93ddf2e94ebc4 346 PRINTS PR00142 RecA protein signature 127 156 7.4E-85 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 K08M4_RS02565 6eac02c7d355d05f07b93ddf2e94ebc4 346 PRINTS PR00142 RecA protein signature 297 314 7.4E-85 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 K08M4_RS02565 6eac02c7d355d05f07b93ddf2e94ebc4 346 Gene3D G3DSA:3.40.50.300 26 267 5.8E-84 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02565 6eac02c7d355d05f07b93ddf2e94ebc4 346 SUPERFAMILY SSF54752 269 324 2.22E-20 T 05-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal K08M4_RS02565 6eac02c7d355d05f07b93ddf2e94ebc4 346 ProSitePatterns PS00321 recA signature. 213 221 - T 05-07-2017 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 K08M4_RS02565 6eac02c7d355d05f07b93ddf2e94ebc4 346 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 324 7.1E-169 T 05-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 K08M4_RS00590 ee2c3d09d94fefc98ca4e881a8711d62 168 Gene3D G3DSA:3.40.1410.10 3 163 1.7E-49 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain K08M4_RS00590 ee2c3d09d94fefc98ca4e881a8711d62 168 SUPERFAMILY SSF64288 5 163 1.02E-40 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain K08M4_RS00590 ee2c3d09d94fefc98ca4e881a8711d62 168 Pfam PF04345 Chorismate lyase 2 167 4.9E-56 T 05-07-2017 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148 K08M4_RS00590 ee2c3d09d94fefc98ca4e881a8711d62 168 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 3 163 23.904 T 05-07-2017 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148 K08M4_RS12300 969a017563a553cca3788f25165bee1d 221 TIGRFAM TIGR02248 mutH_TIGR: DNA mismatch repair endonuclease MutH 5 219 1.2E-101 T 05-07-2017 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 K08M4_RS12300 969a017563a553cca3788f25165bee1d 221 SUPERFAMILY SSF52980 2 220 1.82E-79 T 05-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 K08M4_RS12300 969a017563a553cca3788f25165bee1d 221 Hamap MF_00759 DNA mismatch repair protein MutH [mutH]. 1 221 144.431 T 05-07-2017 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 K08M4_RS12300 969a017563a553cca3788f25165bee1d 221 Gene3D G3DSA:3.40.600.10 3 220 5.9E-80 T 05-07-2017 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 K08M4_RS12300 969a017563a553cca3788f25165bee1d 221 Pfam PF02976 DNA mismatch repair enzyme MutH 53 151 1.1E-33 T 05-07-2017 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 K08M4_RS12300 969a017563a553cca3788f25165bee1d 221 SMART SM00927 53 151 1.7E-63 T 05-07-2017 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 K08M4_RS04895 f9b17761e925792febfa168033925471 676 Pfam PF12344 Ultra-violet resistance protein B 553 595 8.7E-21 T 05-07-2017 IPR024759 UvrB, YAD/RRR-motif-containing domain K08M4_RS04895 f9b17761e925792febfa168033925471 676 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 5 669 0.0 T 05-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 K08M4_RS04895 f9b17761e925792febfa168033925471 676 SUPERFAMILY SSF46600 625 672 3.27E-11 T 05-07-2017 IPR001943 UVR domain GO:0005515 K08M4_RS04895 f9b17761e925792febfa168033925471 676 Gene3D G3DSA:3.40.50.300 6 89 5.3E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04895 f9b17761e925792febfa168033925471 676 Gene3D G3DSA:3.40.50.300 279 339 5.3E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04895 f9b17761e925792febfa168033925471 676 Gene3D G3DSA:3.40.50.300 389 408 5.3E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04895 f9b17761e925792febfa168033925471 676 Gene3D G3DSA:3.30.2060.10 159 231 5.2E-11 T 05-07-2017 K08M4_RS04895 f9b17761e925792febfa168033925471 676 Pfam PF00271 Helicase conserved C-terminal domain 436 546 2.5E-19 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS04895 f9b17761e925792febfa168033925471 676 Gene3D G3DSA:3.40.50.300 420 583 1.1E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04895 f9b17761e925792febfa168033925471 676 Pfam PF04851 Type III restriction enzyme, res subunit 16 129 3.5E-8 T 05-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 K08M4_RS04895 f9b17761e925792febfa168033925471 676 SUPERFAMILY SSF52540 3 416 4.32E-135 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04895 f9b17761e925792febfa168033925471 676 SMART SM00490 461 547 1.3E-20 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS04895 f9b17761e925792febfa168033925471 676 SMART SM00487 9 426 1.8E-27 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS04895 f9b17761e925792febfa168033925471 676 SUPERFAMILY SSF52540 37 82 3.11E-35 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04895 f9b17761e925792febfa168033925471 676 SUPERFAMILY SSF52540 460 578 3.11E-35 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04895 f9b17761e925792febfa168033925471 676 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 671 43.092 T 05-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 K08M4_RS04895 f9b17761e925792febfa168033925471 676 Gene3D G3DSA:4.10.860.10 617 673 8.1E-18 T 05-07-2017 IPR001943 UVR domain GO:0005515 K08M4_RS04895 f9b17761e925792febfa168033925471 676 Pfam PF02151 UvrB/uvrC motif 636 671 1.1E-8 T 05-07-2017 IPR001943 UVR domain GO:0005515 K08M4_RS07070 75dd0e403934d972c8deadafbd36c533 210 Gene3D G3DSA:3.50.30.40 7 167 1.6E-46 T 05-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein K08M4_RS07070 75dd0e403934d972c8deadafbd36c533 210 Pfam PF03737 Demethylmenaquinone methyltransferase 26 158 8.9E-40 T 05-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein K08M4_RS07070 75dd0e403934d972c8deadafbd36c533 210 SUPERFAMILY SSF89562 8 167 2.49E-40 T 05-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein K08M4_RS14130 9355ef1a84909d70ef7a20ea2b03c8d6 90 SUPERFAMILY SSF63562 1 78 8.89E-26 T 05-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 K08M4_RS14130 9355ef1a84909d70ef7a20ea2b03c8d6 90 Pfam PF01192 RNA polymerase Rpb6 10 60 3.1E-18 T 05-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 K08M4_RS14130 9355ef1a84909d70ef7a20ea2b03c8d6 90 Gene3D G3DSA:3.90.940.10 1 77 4.8E-17 T 05-07-2017 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 K08M4_RS14130 9355ef1a84909d70ef7a20ea2b03c8d6 90 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 59 1.8E-29 T 05-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS14130 9355ef1a84909d70ef7a20ea2b03c8d6 90 SMART SM01409 8 61 1.3E-16 T 05-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 K08M4_RS14130 9355ef1a84909d70ef7a20ea2b03c8d6 90 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 16.837 T 05-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS10885 895393a4dfdbed2057b4ae78aa6cefb1 648 SUPERFAMILY SSF47781 386 545 1.56E-25 T 05-07-2017 IPR010994 RuvA domain 2-like K08M4_RS10885 895393a4dfdbed2057b4ae78aa6cefb1 648 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 311 381 4.5E-16 T 05-07-2017 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 K08M4_RS10885 895393a4dfdbed2057b4ae78aa6cefb1 648 Gene3D G3DSA:2.40.50.140 312 379 1.2E-17 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS10885 895393a4dfdbed2057b4ae78aa6cefb1 648 Gene3D G3DSA:3.30.1490.70 208 311 4.6E-9 T 05-07-2017 K08M4_RS10885 895393a4dfdbed2057b4ae78aa6cefb1 648 SUPERFAMILY SSF56091 41 302 4.08E-41 T 05-07-2017 K08M4_RS10885 895393a4dfdbed2057b4ae78aa6cefb1 648 SUPERFAMILY SSF50249 307 382 2.4E-17 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS10885 895393a4dfdbed2057b4ae78aa6cefb1 648 SMART SM00532 38 428 7.4E-18 T 05-07-2017 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 K08M4_RS10885 895393a4dfdbed2057b4ae78aa6cefb1 648 Hamap MF_01588 DNA ligase [ligA]. 33 647 35.556 T 05-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 K08M4_RS10885 895393a4dfdbed2057b4ae78aa6cefb1 648 Gene3D G3DSA:3.40.50.10190 570 647 1.5E-18 T 05-07-2017 IPR001357 BRCT domain K08M4_RS10885 895393a4dfdbed2057b4ae78aa6cefb1 648 Gene3D G3DSA:1.10.150.20 488 544 4.6E-4 T 05-07-2017 K08M4_RS10885 895393a4dfdbed2057b4ae78aa6cefb1 648 SUPERFAMILY SSF52113 569 647 2.33E-12 T 05-07-2017 IPR001357 BRCT domain K08M4_RS10885 895393a4dfdbed2057b4ae78aa6cefb1 648 Gene3D G3DSA:1.10.150.20 416 480 2.8E-4 T 05-07-2017 K08M4_RS10885 895393a4dfdbed2057b4ae78aa6cefb1 648 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 51 221 4.8E-13 T 05-07-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 K08M4_RS10885 895393a4dfdbed2057b4ae78aa6cefb1 648 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 252 303 3.9E-4 T 05-07-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 K08M4_RS10885 895393a4dfdbed2057b4ae78aa6cefb1 648 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 573 647 1.5E-9 T 05-07-2017 IPR001357 BRCT domain K08M4_RS05930 defadd86f6a118b8c65b05ef2eec16e4 411 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 403 5.0E-160 T 05-07-2017 IPR011340 Cysteine desulfurase-related K08M4_RS05930 defadd86f6a118b8c65b05ef2eec16e4 411 SUPERFAMILY SSF53383 5 409 4.44E-96 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS05930 defadd86f6a118b8c65b05ef2eec16e4 411 Pfam PF00266 Aminotransferase class-V 26 400 5.6E-68 T 05-07-2017 IPR000192 Aminotransferase class V domain K08M4_RS05930 defadd86f6a118b8c65b05ef2eec16e4 411 Gene3D G3DSA:3.40.640.10 36 269 6.1E-64 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS05930 defadd86f6a118b8c65b05ef2eec16e4 411 Gene3D G3DSA:3.90.1150.10 270 409 4.2E-35 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS17055 4932fd7886be947a0351b8e07bbc2274 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 124 1.9E-19 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain K08M4_RS17055 4932fd7886be947a0351b8e07bbc2274 127 SUPERFAMILY SSF54593 1 126 5.1E-31 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS17055 4932fd7886be947a0351b8e07bbc2274 127 Gene3D G3DSA:3.10.180.10 7 126 4.3E-32 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS03065 7781dbf5ba6a2cf2dc25de7b4e39bf67 157 Gene3D G3DSA:3.10.50.30 79 156 2.8E-30 T 05-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 K08M4_RS03065 7781dbf5ba6a2cf2dc25de7b4e39bf67 157 SUPERFAMILY SSF46557 2 75 2.09E-24 T 05-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 K08M4_RS03065 7781dbf5ba6a2cf2dc25de7b4e39bf67 157 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 155 31.207 T 05-07-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 K08M4_RS03065 7781dbf5ba6a2cf2dc25de7b4e39bf67 157 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 47 - T 05-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 K08M4_RS03065 7781dbf5ba6a2cf2dc25de7b4e39bf67 157 PIRSF PIRSF006092 1 157 3.5E-44 T 05-07-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 K08M4_RS03065 7781dbf5ba6a2cf2dc25de7b4e39bf67 157 Gene3D G3DSA:1.10.287.180 1 74 7.0E-28 T 05-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 K08M4_RS03065 7781dbf5ba6a2cf2dc25de7b4e39bf67 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 82 156 1.3E-26 T 05-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 K08M4_RS03065 7781dbf5ba6a2cf2dc25de7b4e39bf67 157 Pfam PF03449 Transcription elongation factor, N-terminal 4 73 7.0E-24 T 05-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 K08M4_RS03065 7781dbf5ba6a2cf2dc25de7b4e39bf67 157 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 120 136 - T 05-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 K08M4_RS03065 7781dbf5ba6a2cf2dc25de7b4e39bf67 157 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 155 2.9E-51 T 05-07-2017 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 K08M4_RS03065 7781dbf5ba6a2cf2dc25de7b4e39bf67 157 SUPERFAMILY SSF54534 81 156 4.71E-23 T 05-07-2017 K08M4_RS21030 a9397842825924e26f5f083faeef42cf 382 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 13 380 8.2E-226 T 05-07-2017 IPR014183 Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|Reactome: R-HSA-71384 K08M4_RS21030 a9397842825924e26f5f083faeef42cf 382 Pfam PF00107 Zinc-binding dehydrogenase 208 337 2.4E-25 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 K08M4_RS21030 a9397842825924e26f5f083faeef42cf 382 SUPERFAMILY SSF51735 171 345 4.59E-49 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS21030 a9397842825924e26f5f083faeef42cf 382 SUPERFAMILY SSF50129 329 379 5.18E-11 T 05-07-2017 IPR011032 GroES-like K08M4_RS21030 a9397842825924e26f5f083faeef42cf 382 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 72 86 - T 05-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 K08M4_RS21030 a9397842825924e26f5f083faeef42cf 382 SUPERFAMILY SSF50129 10 196 2.06E-71 T 05-07-2017 IPR011032 GroES-like K08M4_RS21030 a9397842825924e26f5f083faeef42cf 382 Gene3D G3DSA:3.90.180.10 9 200 5.0E-67 T 05-07-2017 IPR011032 GroES-like K08M4_RS21030 a9397842825924e26f5f083faeef42cf 382 SMART SM00829 23 378 0.0083 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 K08M4_RS21030 a9397842825924e26f5f083faeef42cf 382 Gene3D G3DSA:3.40.50.720 201 320 2.7E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS21030 a9397842825924e26f5f083faeef42cf 382 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 39 165 3.0E-25 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 K08M4_RS00495 e423b6482ba3e3996f2a32b82c607174 333 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 152 4.2E-51 T 05-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS00495 e423b6482ba3e3996f2a32b82c607174 333 SUPERFAMILY SSF55347 152 314 8.04E-64 T 05-07-2017 K08M4_RS00495 e423b6482ba3e3996f2a32b82c607174 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 108 121 2.7E-29 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS00495 e423b6482ba3e3996f2a32b82c607174 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 2.7E-29 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS00495 e423b6482ba3e3996f2a32b82c607174 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 2.7E-29 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS00495 e423b6482ba3e3996f2a32b82c607174 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 2.7E-29 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS00495 e423b6482ba3e3996f2a32b82c607174 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 2.7E-29 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS00495 e423b6482ba3e3996f2a32b82c607174 333 SUPERFAMILY SSF51735 1 180 3.33E-54 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS00495 e423b6482ba3e3996f2a32b82c607174 333 Gene3D G3DSA:3.40.50.720 2 160 5.2E-62 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS00495 e423b6482ba3e3996f2a32b82c607174 333 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 2.2E-59 T 05-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS00495 e423b6482ba3e3996f2a32b82c607174 333 Gene3D G3DSA:3.30.360.10 161 315 3.9E-67 T 05-07-2017 K08M4_RS00495 e423b6482ba3e3996f2a32b82c607174 333 PIRSF PIRSF000149 1 331 3.1E-115 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS00495 e423b6482ba3e3996f2a32b82c607174 333 SMART SM00846 3 152 8.4E-72 T 05-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS00495 e423b6482ba3e3996f2a32b82c607174 333 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 05-07-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS00495 e423b6482ba3e3996f2a32b82c607174 333 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 323 1.5E-119 T 05-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS11590 ccbbb2f151b57dfdcef5d7eaa2311641 1158 SUPERFAMILY SSF52540 377 826 6.8E-107 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11590 ccbbb2f151b57dfdcef5d7eaa2311641 1158 Gene3D G3DSA:3.40.50.300 360 462 1.3E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11590 ccbbb2f151b57dfdcef5d7eaa2311641 1158 Gene3D G3DSA:3.40.50.300 668 764 1.3E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11590 ccbbb2f151b57dfdcef5d7eaa2311641 1158 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 2 820 1.0E-299 T 05-07-2017 K08M4_RS11590 ccbbb2f151b57dfdcef5d7eaa2311641 1158 SUPERFAMILY SSF52980 843 1143 5.36E-75 T 05-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 K08M4_RS11590 ccbbb2f151b57dfdcef5d7eaa2311641 1158 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 1 1135 20.825 T 05-07-2017 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 K08M4_RS11590 ccbbb2f151b57dfdcef5d7eaa2311641 1158 Gene3D G3DSA:1.10.10.160 86 188 7.5E-33 T 05-07-2017 IPR013986 DExx box DNA helicase domain K08M4_RS11590 ccbbb2f151b57dfdcef5d7eaa2311641 1158 PIRSF PIRSF000980 1 1157 0.0 T 05-07-2017 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 K08M4_RS11590 ccbbb2f151b57dfdcef5d7eaa2311641 1158 SUPERFAMILY SSF52540 2 357 8.5E-120 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11590 ccbbb2f151b57dfdcef5d7eaa2311641 1158 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 2 1116 0.0 T 05-07-2017 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 K08M4_RS11775 f95161efd64d45778be7e8662fdbb225 461 SMART SM00849 13 223 9.7E-18 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS11775 f95161efd64d45778be7e8662fdbb225 461 Pfam PF00753 Metallo-beta-lactamase superfamily 14 217 1.1E-11 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS11775 f95161efd64d45778be7e8662fdbb225 461 Gene3D G3DSA:3.60.15.10 144 263 5.2E-38 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS11775 f95161efd64d45778be7e8662fdbb225 461 Gene3D G3DSA:3.60.15.10 3 111 5.2E-38 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS11775 f95161efd64d45778be7e8662fdbb225 461 Pfam PF10996 Beta-Casp domain 257 387 1.6E-27 T 05-07-2017 IPR022712 Beta-Casp domain K08M4_RS11775 f95161efd64d45778be7e8662fdbb225 461 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 401 457 6.9E-14 T 05-07-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain K08M4_RS11775 f95161efd64d45778be7e8662fdbb225 461 SUPERFAMILY SSF56281 1 456 8.91E-122 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS11775 f95161efd64d45778be7e8662fdbb225 461 SMART SM01027 257 387 3.7E-55 T 05-07-2017 IPR022712 Beta-Casp domain K08M4_RS16135 b958f96b651a887c54c8a99d16aa3dd4 463 Pfam PF01769 Divalent cation transporter 333 454 3.9E-21 T 05-07-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 K08M4_RS16135 b958f96b651a887c54c8a99d16aa3dd4 463 SUPERFAMILY SSF54631 145 281 6.47E-13 T 05-07-2017 K08M4_RS16135 b958f96b651a887c54c8a99d16aa3dd4 463 Gene3D G3DSA:1.10.357.20 295 462 4.7E-36 T 05-07-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 K08M4_RS16135 b958f96b651a887c54c8a99d16aa3dd4 463 Gene3D G3DSA:1.25.60.10 18 118 2.1E-6 T 05-07-2017 K08M4_RS16135 b958f96b651a887c54c8a99d16aa3dd4 463 Pfam PF03448 MgtE intracellular N domain 51 141 7.2E-8 T 05-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain K08M4_RS16135 b958f96b651a887c54c8a99d16aa3dd4 463 Gene3D G3DSA:3.10.580.10 144 267 4.0E-9 T 05-07-2017 K08M4_RS16135 b958f96b651a887c54c8a99d16aa3dd4 463 SUPERFAMILY SSF158791 48 119 3.66E-8 T 05-07-2017 K08M4_RS16135 b958f96b651a887c54c8a99d16aa3dd4 463 SUPERFAMILY SSF161093 292 462 1.12E-35 T 05-07-2017 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 Gene3D G3DSA:3.40.50.1370 144 321 1.1E-72 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 4.0E-32 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 230 240 4.0E-32 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 4.0E-32 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 4.0E-32 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 313 324 4.0E-32 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 8.1E-25 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 8.1E-25 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 277 8.1E-25 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 299 322 8.1E-25 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 SUPERFAMILY SSF53671 4 335 9.69E-100 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 334 6.6E-132 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 335 82.481 T 05-07-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 4.1E-45 T 05-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 Gene3D G3DSA:3.40.50.1370 5 143 2.1E-54 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01015 2141fdb04a67979f1cb2bc6d51e4f329 336 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 332 7.7E-58 T 05-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 SMART SM00495 794 839 1.9E-10 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 SUPERFAMILY SSF54556 461 546 2.17E-17 T 05-07-2017 IPR029070 Chitinase insertion domain K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 Gene3D G3DSA:2.60.40.10 23 132 2.6E-38 T 05-07-2017 IPR013783 Immunoglobulin-like fold K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 SUPERFAMILY SSF51445 135 461 1.66E-88 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 SUPERFAMILY SSF51445 548 588 1.66E-88 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 Pfam PF02839 Carbohydrate binding domain 795 836 5.1E-10 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 Pfam PF08329 Chitinase A, N-terminal domain 21 156 2.4E-53 T 05-07-2017 IPR013540 Chitinase A N-terminal GO:0004568|GO:0006032 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 SUPERFAMILY SSF81296 21 133 1.13E-30 T 05-07-2017 IPR014756 Immunoglobulin E-set K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 ProSitePatterns PS01095 Chitinases family 18 active site. 307 315 - T 05-07-2017 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 Gene3D G3DSA:3.10.50.10 463 548 1.4E-23 T 05-07-2017 IPR029070 Chitinase insertion domain K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 Gene3D G3DSA:2.10.10.20 792 839 2.9E-16 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 Pfam PF00704 Glycosyl hydrolases family 18 161 575 8.8E-82 T 05-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 SUPERFAMILY SSF49299 596 689 3.73E-8 T 05-07-2017 IPR000601 PKD domain K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 SMART SM00089 700 786 2.4 T 05-07-2017 IPR022409 PKD/Chitinase domain K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 SMART SM00089 62 134 4.3 T 05-07-2017 IPR022409 PKD/Chitinase domain K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 SMART SM00089 600 690 0.004 T 05-07-2017 IPR022409 PKD/Chitinase domain K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 SUPERFAMILY SSF51055 790 841 2.75E-13 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 Gene3D G3DSA:3.20.20.80 552 593 1.8E-115 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 Gene3D G3DSA:3.20.20.80 137 462 1.8E-115 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS21400 c4343a7971414ce23e05b57ad0a3689f 846 SMART SM00636 159 575 1.9E-155 T 05-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 K08M4_RS09005 f9ca70f26b80019fbcd169ed08bfb92f 217 Pfam PF00753 Metallo-beta-lactamase superfamily 14 194 3.8E-28 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS09005 f9ca70f26b80019fbcd169ed08bfb92f 217 SUPERFAMILY SSF56281 5 210 8.12E-55 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS09005 f9ca70f26b80019fbcd169ed08bfb92f 217 SMART SM00849 14 194 2.0E-36 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS09005 f9ca70f26b80019fbcd169ed08bfb92f 217 Gene3D G3DSA:3.60.15.10 3 212 2.5E-57 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS02580 a36bcf6445c51cfeb99d8f71c42c5124 612 SUPERFAMILY SSF81296 14 130 5.88E-18 T 05-07-2017 IPR014756 Immunoglobulin E-set K08M4_RS02580 a36bcf6445c51cfeb99d8f71c42c5124 612 SUPERFAMILY SSF51445 95 550 9.6E-124 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS02580 a36bcf6445c51cfeb99d8f71c42c5124 612 SMART SM00642 176 544 3.5E-123 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS02580 a36bcf6445c51cfeb99d8f71c42c5124 612 Pfam PF00128 Alpha amylase, catalytic domain 209 511 2.7E-84 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS02580 a36bcf6445c51cfeb99d8f71c42c5124 612 Gene3D G3DSA:2.60.40.10 17 162 1.4E-37 T 05-07-2017 IPR013783 Immunoglobulin-like fold K08M4_RS02580 a36bcf6445c51cfeb99d8f71c42c5124 612 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 18 158 3.5E-24 T 05-07-2017 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 K08M4_RS02580 a36bcf6445c51cfeb99d8f71c42c5124 612 Gene3D G3DSA:3.20.20.80 165 545 2.0E-119 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS21575 9dd48c0286002abed18005015f9ec409 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 K08M4_RS21575 9dd48c0286002abed18005015f9ec409 243 Gene3D G3DSA:3.40.50.720 3 241 3.5E-46 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS21575 9dd48c0286002abed18005015f9ec409 243 Pfam PF00106 short chain dehydrogenase 3 185 4.5E-37 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS21575 9dd48c0286002abed18005015f9ec409 243 SUPERFAMILY SSF51735 2 240 2.67E-50 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS21575 9dd48c0286002abed18005015f9ec409 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.3E-20 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS21575 9dd48c0286002abed18005015f9ec409 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.3E-20 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS21575 9dd48c0286002abed18005015f9ec409 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.3E-20 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS21575 9dd48c0286002abed18005015f9ec409 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.3E-20 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS21575 9dd48c0286002abed18005015f9ec409 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.3E-20 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS21575 9dd48c0286002abed18005015f9ec409 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 4.9E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS21575 9dd48c0286002abed18005015f9ec409 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 4.9E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS21575 9dd48c0286002abed18005015f9ec409 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 4.9E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS04035 d70a1aaa3f397d28e825b019beb10717 275 SUPERFAMILY SSF47757 3 75 9.81E-15 T 05-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal K08M4_RS04035 d70a1aaa3f397d28e825b019beb10717 275 Gene3D G3DSA:3.40.50.150 75 270 4.2E-64 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS04035 d70a1aaa3f397d28e825b019beb10717 275 SUPERFAMILY SSF53335 76 269 2.23E-51 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS04035 d70a1aaa3f397d28e825b019beb10717 275 SMART SM00138 8 272 4.5E-133 T 05-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 K08M4_RS04035 d70a1aaa3f397d28e825b019beb10717 275 Pfam PF03705 CheR methyltransferase, all-alpha domain 9 57 1.2E-9 T 05-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal K08M4_RS04035 d70a1aaa3f397d28e825b019beb10717 275 Gene3D G3DSA:1.10.155.10 3 74 5.8E-15 T 05-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal K08M4_RS04035 d70a1aaa3f397d28e825b019beb10717 275 PRINTS PR00996 Glutamate methyltransferase family signature 143 159 1.5E-42 T 05-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 K08M4_RS04035 d70a1aaa3f397d28e825b019beb10717 275 PRINTS PR00996 Glutamate methyltransferase family signature 30 43 1.5E-42 T 05-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 K08M4_RS04035 d70a1aaa3f397d28e825b019beb10717 275 PRINTS PR00996 Glutamate methyltransferase family signature 212 226 1.5E-42 T 05-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 K08M4_RS04035 d70a1aaa3f397d28e825b019beb10717 275 PRINTS PR00996 Glutamate methyltransferase family signature 106 126 1.5E-42 T 05-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 K08M4_RS04035 d70a1aaa3f397d28e825b019beb10717 275 PRINTS PR00996 Glutamate methyltransferase family signature 231 254 1.5E-42 T 05-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 K08M4_RS04035 d70a1aaa3f397d28e825b019beb10717 275 PRINTS PR00996 Glutamate methyltransferase family signature 69 81 1.5E-42 T 05-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 K08M4_RS04035 d70a1aaa3f397d28e825b019beb10717 275 Pfam PF01739 CheR methyltransferase, SAM binding domain 76 269 6.6E-68 T 05-07-2017 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal K08M4_RS14060 d779da09c912d14c1ad9d2b5dab0c7fa 258 SMART SM00420 6 58 4.2E-11 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 K08M4_RS14060 d779da09c912d14c1ad9d2b5dab0c7fa 258 Gene3D G3DSA:3.40.50.1360 86 222 5.1E-4 T 05-07-2017 K08M4_RS14060 d779da09c912d14c1ad9d2b5dab0c7fa 258 Gene3D G3DSA:1.10.10.10 5 55 1.6E-4 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS14060 d779da09c912d14c1ad9d2b5dab0c7fa 258 SUPERFAMILY SSF100950 86 238 4.08E-18 T 05-07-2017 K08M4_RS14060 d779da09c912d14c1ad9d2b5dab0c7fa 258 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 05-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 K08M4_RS14060 d779da09c912d14c1ad9d2b5dab0c7fa 258 SMART SM01134 81 239 4.9E-31 T 05-07-2017 K08M4_RS14060 d779da09c912d14c1ad9d2b5dab0c7fa 258 Pfam PF08220 DeoR-like helix-turn-helix domain 6 59 5.5E-13 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 K08M4_RS14060 d779da09c912d14c1ad9d2b5dab0c7fa 258 Pfam PF00455 DeoR C terminal sensor domain 84 237 5.5E-32 T 05-07-2017 IPR014036 DeoR C-terminal sensor domain K08M4_RS14060 d779da09c912d14c1ad9d2b5dab0c7fa 258 SUPERFAMILY SSF46785 5 63 7.98E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS04615 ff31621567cbfe4af775c7eb87b18db8 109 PIRSF PIRSF004555 3 109 1.0E-39 T 05-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family K08M4_RS04615 ff31621567cbfe4af775c7eb87b18db8 109 Pfam PF02575 YbaB/EbfC DNA-binding family 11 100 2.2E-35 T 05-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family K08M4_RS04615 ff31621567cbfe4af775c7eb87b18db8 109 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 98 23.583 T 05-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family K08M4_RS04615 ff31621567cbfe4af775c7eb87b18db8 109 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 105 6.8E-40 T 05-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family K08M4_RS04615 ff31621567cbfe4af775c7eb87b18db8 109 Gene3D G3DSA:3.30.1310.10 1 109 2.0E-51 T 05-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family K08M4_RS04615 ff31621567cbfe4af775c7eb87b18db8 109 SUPERFAMILY SSF82607 11 103 1.03E-36 T 05-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family K08M4_RS11185 46dff187bc3f5919f795a4f7873560a7 801 Pfam PF01103 Surface antigen 448 801 1.6E-86 T 05-07-2017 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020 K08M4_RS11185 46dff187bc3f5919f795a4f7873560a7 801 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 24 801 4.7E-276 T 05-07-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 K08M4_RS11185 46dff187bc3f5919f795a4f7873560a7 801 PIRSF PIRSF006076 1 801 1.5E-241 T 05-07-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 K08M4_RS11185 46dff187bc3f5919f795a4f7873560a7 801 Pfam PF07244 Surface antigen variable number repeat 347 420 1.3E-16 T 05-07-2017 IPR010827 Surface antigen variable number GO:0019867 K08M4_RS11185 46dff187bc3f5919f795a4f7873560a7 801 Pfam PF07244 Surface antigen variable number repeat 176 263 3.1E-15 T 05-07-2017 IPR010827 Surface antigen variable number GO:0019867 K08M4_RS11185 46dff187bc3f5919f795a4f7873560a7 801 Pfam PF07244 Surface antigen variable number repeat 266 344 3.0E-10 T 05-07-2017 IPR010827 Surface antigen variable number GO:0019867 K08M4_RS11185 46dff187bc3f5919f795a4f7873560a7 801 Pfam PF07244 Surface antigen variable number repeat 92 172 2.6E-11 T 05-07-2017 IPR010827 Surface antigen variable number GO:0019867 K08M4_RS11185 46dff187bc3f5919f795a4f7873560a7 801 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 2 801 25.725 T 05-07-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 SMART SM00896 719 812 4.0E-42 T 05-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 Gene3D G3DSA:3.30.930.10 502 707 6.2E-62 T 05-07-2017 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 SUPERFAMILY SSF56037 203 397 2.43E-77 T 05-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 SUPERFAMILY SSF50249 35 203 2.34E-44 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 SUPERFAMILY SSF54991 715 812 1.83E-28 T 05-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 Gene3D G3DSA:3.30.70.380 721 812 1.3E-28 T 05-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 SMART SM00873 218 391 1.3E-100 T 05-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 SUPERFAMILY SSF46955 410 487 9.16E-18 T 05-07-2017 IPR009061 Putative DNA-binding domain K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 Pfam PF03483 B3/4 domain 218 391 1.3E-72 T 05-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 Pfam PF03147 Ferredoxin-fold anticodon binding domain 719 812 2.9E-26 T 05-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 Gene3D G3DSA:3.50.40.10 204 397 3.7E-87 T 05-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 Pfam PF01588 Putative tRNA binding domain 45 151 5.6E-22 T 05-07-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 812 2.1E-269 T 05-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 Gene3D G3DSA:3.30.56.10 161 190 4.7E-27 T 05-07-2017 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 Gene3D G3DSA:3.30.56.10 1 38 4.7E-27 T 05-07-2017 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 Gene3D G3DSA:3.30.56.20 409 487 2.9E-25 T 05-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 Gene3D G3DSA:2.40.50.140 40 160 3.8E-40 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 Pfam PF03484 tRNA synthetase B5 domain 412 483 6.6E-19 T 05-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 SMART SM00874 409 483 4.7E-29 T 05-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 806 45.514 T 05-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 K08M4_RS08275 c0e370f595f2de3a591076b66d441b5f 813 SUPERFAMILY SSF55681 479 707 1.39E-49 T 05-07-2017 K08M4_RS20360 49aa11a3c4ddf44928170661f06a4b09 277 Gene3D G3DSA:1.10.10.10 191 213 7.7E-4 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20360 49aa11a3c4ddf44928170661f06a4b09 277 Gene3D G3DSA:1.10.10.10 71 112 2.6E-5 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20360 49aa11a3c4ddf44928170661f06a4b09 277 Pfam PF02631 RecX family 192 274 8.9E-11 T 05-07-2017 IPR003783 Regulatory protein RecX GO:0006282 K08M4_RS20360 49aa11a3c4ddf44928170661f06a4b09 277 Pfam PF02631 RecX family 49 164 2.3E-18 T 05-07-2017 IPR003783 Regulatory protein RecX GO:0006282 K08M4_RS20360 49aa11a3c4ddf44928170661f06a4b09 277 Gene3D G3DSA:1.10.10.10 23 69 2.4E-7 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20360 49aa11a3c4ddf44928170661f06a4b09 277 Gene3D G3DSA:1.10.10.10 246 274 8.6E-4 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS13715 8d8d9e326b0d8d1abf73ed64876b20d5 548 Gene3D G3DSA:1.10.560.10 3 201 1.7E-49 T 05-07-2017 IPR027413 GroEL-like equatorial domain K08M4_RS13715 8d8d9e326b0d8d1abf73ed64876b20d5 548 Gene3D G3DSA:3.50.7.10 202 369 6.6E-93 T 05-07-2017 IPR027409 GroEL-like apical domain K08M4_RS13715 8d8d9e326b0d8d1abf73ed64876b20d5 548 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 525 4.7E-97 T 05-07-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 K08M4_RS13715 8d8d9e326b0d8d1abf73ed64876b20d5 548 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 05-07-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 K08M4_RS13715 8d8d9e326b0d8d1abf73ed64876b20d5 548 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 527 1.5E-252 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 K08M4_RS13715 8d8d9e326b0d8d1abf73ed64876b20d5 548 SUPERFAMILY SSF52029 185 376 7.78E-83 T 05-07-2017 IPR027409 GroEL-like apical domain K08M4_RS13715 8d8d9e326b0d8d1abf73ed64876b20d5 548 PRINTS PR00298 60kDa chaperonin signature 350 375 2.5E-74 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 K08M4_RS13715 8d8d9e326b0d8d1abf73ed64876b20d5 548 PRINTS PR00298 60kDa chaperonin signature 83 110 2.5E-74 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 K08M4_RS13715 8d8d9e326b0d8d1abf73ed64876b20d5 548 PRINTS PR00298 60kDa chaperonin signature 27 53 2.5E-74 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 K08M4_RS13715 8d8d9e326b0d8d1abf73ed64876b20d5 548 PRINTS PR00298 60kDa chaperonin signature 398 419 2.5E-74 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 K08M4_RS13715 8d8d9e326b0d8d1abf73ed64876b20d5 548 PRINTS PR00298 60kDa chaperonin signature 268 291 2.5E-74 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 K08M4_RS13715 8d8d9e326b0d8d1abf73ed64876b20d5 548 Hamap MF_00600 60 kDa chaperonin [groL]. 2 547 41.45 T 05-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 K08M4_RS13715 8d8d9e326b0d8d1abf73ed64876b20d5 548 SUPERFAMILY SSF48592 373 525 6.11E-32 T 05-07-2017 K08M4_RS13715 8d8d9e326b0d8d1abf73ed64876b20d5 548 Gene3D G3DSA:1.10.560.10 370 518 3.2E-40 T 05-07-2017 IPR027413 GroEL-like equatorial domain K08M4_RS13715 8d8d9e326b0d8d1abf73ed64876b20d5 548 SUPERFAMILY SSF48592 3 230 1.06E-64 T 05-07-2017 K08M4_RS11320 9d01975a25d90666aca8fa3c692b3892 67 ProDom PD054643 UPF0253 YAEP CYTOPLASMIC VP2335 YPO1064.1/Y3113/YP2785 VC0872 VV2574 PBPRA2947 VV11836 7 65 4.0E-18 T 05-07-2017 IPR009624 Uncharacterised protein family UPF0253 K08M4_RS11320 9d01975a25d90666aca8fa3c692b3892 67 Hamap MF_01064 UPF0253 protein YaeP [yaeP]. 1 67 25.98 T 05-07-2017 IPR009624 Uncharacterised protein family UPF0253 K08M4_RS11320 9d01975a25d90666aca8fa3c692b3892 67 Pfam PF06786 Uncharacterised protein family (UPF0253) 1 67 4.2E-34 T 05-07-2017 IPR009624 Uncharacterised protein family UPF0253 K08M4_RS14605 69349fc5b264a1a8d6198f73ce103a7d 517 Gene3D G3DSA:3.10.105.10 285 486 1.2E-53 T 05-07-2017 K08M4_RS14605 69349fc5b264a1a8d6198f73ce103a7d 517 SUPERFAMILY SSF53850 26 516 3.44E-124 T 05-07-2017 K08M4_RS14605 69349fc5b264a1a8d6198f73ce103a7d 517 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 67 424 7.8E-84 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain K08M4_RS14605 69349fc5b264a1a8d6198f73ce103a7d 517 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 72 93 - T 05-07-2017 IPR023765 Solute-binding protein family 5, conserved site K08M4_RS14605 69349fc5b264a1a8d6198f73ce103a7d 517 Gene3D G3DSA:3.40.190.10 125 284 4.3E-38 T 05-07-2017 K08M4_RS14605 69349fc5b264a1a8d6198f73ce103a7d 517 PIRSF PIRSF002741 20 513 1.5E-91 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 Pfam PF03174 Chitobiase/beta-hexosaminidase C-terminal domain 805 880 2.2E-26 T 05-07-2017 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 Pfam PF03173 Putative carbohydrate binding domain 35 193 1.2E-62 T 05-07-2017 IPR004866 Chitobiase/beta-hexosaminidases, N-terminal domain KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 211 329 2.9E-13 T 05-07-2017 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 Gene3D G3DSA:3.20.20.80 330 832 8.0E-152 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 Gene3D G3DSA:3.30.379.10 206 329 8.5E-23 T 05-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 SUPERFAMILY SSF81296 781 883 1.11E-35 T 05-07-2017 IPR014756 Immunoglobulin E-set K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 SUPERFAMILY SSF55545 208 331 1.79E-23 T 05-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 Gene3D G3DSA:2.60.40.320 833 883 3.1E-26 T 05-07-2017 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 SUPERFAMILY SSF49384 26 198 2.3E-66 T 05-07-2017 IPR008965 Carbohydrate-binding domain GO:0030246 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 PRINTS PR00738 Glycosyl hydrolase family 20 signature 729 745 3.1E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 PRINTS PR00738 Glycosyl hydrolase family 20 signature 432 449 3.1E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 PRINTS PR00738 Glycosyl hydrolase family 20 signature 499 517 3.1E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 PRINTS PR00738 Glycosyl hydrolase family 20 signature 326 343 3.1E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 PRINTS PR00738 Glycosyl hydrolase family 20 signature 355 376 3.1E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 PRINTS PR00738 Glycosyl hydrolase family 20 signature 747 764 3.1E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 PRINTS PR00738 Glycosyl hydrolase family 20 signature 292 312 3.1E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 PRINTS PR00738 Glycosyl hydrolase family 20 signature 526 539 3.1E-48 T 05-07-2017 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 Gene3D G3DSA:2.60.40.290 26 167 2.3E-61 T 05-07-2017 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 SUPERFAMILY SSF51445 332 773 2.82E-139 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 SMART SM01081 34 195 5.9E-91 T 05-07-2017 IPR004866 Chitobiase/beta-hexosaminidases, N-terminal domain KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 K08M4_RS03870 07c4180cfa9a11d9a09e1efa2c582430 884 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 332 765 5.1E-106 T 05-07-2017 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 K08M4_RS05650 472cf812b2b8438843264d899f1cabc4 308 SUPERFAMILY SSF53850 94 299 2.68E-34 T 05-07-2017 K08M4_RS05650 472cf812b2b8438843264d899f1cabc4 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.1E-11 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS05650 472cf812b2b8438843264d899f1cabc4 308 Gene3D G3DSA:3.40.190.10 180 262 3.6E-13 T 05-07-2017 K08M4_RS05650 472cf812b2b8438843264d899f1cabc4 308 SUPERFAMILY SSF46785 3 99 9.36E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05650 472cf812b2b8438843264d899f1cabc4 308 Gene3D G3DSA:3.40.190.10 94 179 4.5E-11 T 05-07-2017 K08M4_RS05650 472cf812b2b8438843264d899f1cabc4 308 Pfam PF03466 LysR substrate binding domain 92 297 8.9E-36 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS05650 472cf812b2b8438843264d899f1cabc4 308 Gene3D G3DSA:1.10.10.10 4 89 6.3E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS01225 6283f587a4301446c5cd04c9c5217a64 115 SUPERFAMILY SSF55298 4 113 5.34E-33 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS01225 6283f587a4301446c5cd04c9c5217a64 115 Gene3D G3DSA:3.30.1330.40 6 114 5.5E-29 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS01225 6283f587a4301446c5cd04c9c5217a64 115 Pfam PF01042 Endoribonuclease L-PSP 7 113 3.3E-25 T 05-07-2017 IPR006175 YjgF/YER057c/UK114 family K08M4_RS03490 6b63fedea3cfa682ccbb8125199dcb40 149 Pfam PF03477 ATP cone domain 50 136 2.2E-17 T 05-07-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 K08M4_RS03490 6b63fedea3cfa682ccbb8125199dcb40 149 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 149 90.162 T 05-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 K08M4_RS03490 6b63fedea3cfa682ccbb8125199dcb40 149 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 3.7E-73 T 05-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 SMART SM00260 584 725 3.1E-35 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 Gene3D G3DSA:3.30.565.10 407 591 2.2E-36 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 SMART SM00387 449 592 1.2E-21 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 Pfam PF01584 CheW-like domain 598 727 4.3E-22 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 Pfam PF01627 Hpt domain 8 99 3.5E-17 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 Gene3D G3DSA:2.30.30.40 592 613 2.3E-21 T 05-07-2017 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 Gene3D G3DSA:2.30.30.40 681 725 2.3E-21 T 05-07-2017 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 508 3.1E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 PRINTS PR00344 Bacterial sensor protein C-terminal signature 536 546 3.1E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 570 3.1E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 PRINTS PR00344 Bacterial sensor protein C-terminal signature 576 589 3.1E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 SUPERFAMILY SSF47384 346 405 5.1E-14 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 Gene3D G3DSA:1.20.120.160 4 143 4.5E-43 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 Gene3D G3DSA:1.10.287.560 345 405 6.6E-19 T 05-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 SMART SM01231 344 404 1.4E-17 T 05-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 345 404 2.6E-12 T 05-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 SMART SM00073 6 103 2.8E-17 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 SUPERFAMILY SSF47226 6 128 4.58E-30 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 Gene3D G3DSA:2.40.50.180 616 680 6.3E-12 T 05-07-2017 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 452 591 8.2E-18 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 SUPERFAMILY SSF50341 591 725 2.75E-29 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS04255 d578814c75d9b5814b255da418990ad3 734 SUPERFAMILY SSF55874 407 590 1.7E-38 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS01660 22ec882b28c2de026c81e65cc43b5a07 658 Pfam PF02872 5'-nucleotidase, C-terminal domain 367 559 3.6E-23 T 05-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS01660 22ec882b28c2de026c81e65cc43b5a07 658 PRINTS PR01607 Apyrase family signature 541 560 1.7E-27 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS01660 22ec882b28c2de026c81e65cc43b5a07 658 PRINTS PR01607 Apyrase family signature 294 314 1.7E-27 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS01660 22ec882b28c2de026c81e65cc43b5a07 658 PRINTS PR01607 Apyrase family signature 33 51 1.7E-27 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS01660 22ec882b28c2de026c81e65cc43b5a07 658 PRINTS PR01607 Apyrase family signature 226 243 1.7E-27 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS01660 22ec882b28c2de026c81e65cc43b5a07 658 PRINTS PR01607 Apyrase family signature 254 277 1.7E-27 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS01660 22ec882b28c2de026c81e65cc43b5a07 658 PRINTS PR01607 Apyrase family signature 439 462 1.7E-27 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS01660 22ec882b28c2de026c81e65cc43b5a07 658 ProSitePatterns PS00786 5'-nucleotidase signature 2. 120 131 - T 05-07-2017 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS01660 22ec882b28c2de026c81e65cc43b5a07 658 Gene3D G3DSA:3.60.21.10 27 370 3.1E-91 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS01660 22ec882b28c2de026c81e65cc43b5a07 658 SUPERFAMILY SSF56300 30 365 2.95E-84 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS01660 22ec882b28c2de026c81e65cc43b5a07 658 TIGRFAM TIGR01390 CycNucDiestase: 2',3'-cyclic-nucleotide 2'-phosphodiesterase 34 658 0.0 T 05-07-2017 IPR006294 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase GO:0008663|GO:0009117 KEGG: 00230+3.1.4.16+3.1.3.6|KEGG: 00240+3.1.4.16+3.1.3.6 K08M4_RS01660 22ec882b28c2de026c81e65cc43b5a07 658 Pfam PF00149 Calcineurin-like phosphoesterase 35 270 2.2E-11 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 K08M4_RS01660 22ec882b28c2de026c81e65cc43b5a07 658 Gene3D G3DSA:3.90.780.10 371 607 4.6E-40 T 05-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS01660 22ec882b28c2de026c81e65cc43b5a07 658 SUPERFAMILY SSF55816 366 608 3.27E-36 T 05-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS15465 13ded71a10168efaf05bd4227df87fef 293 SUPERFAMILY SSF46785 6 86 8.62E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15465 13ded71a10168efaf05bd4227df87fef 293 Pfam PF03466 LysR substrate binding domain 90 291 6.6E-40 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS15465 13ded71a10168efaf05bd4227df87fef 293 Gene3D G3DSA:3.40.190.10 93 177 2.5E-25 T 05-07-2017 K08M4_RS15465 13ded71a10168efaf05bd4227df87fef 293 Gene3D G3DSA:1.10.10.10 6 84 2.6E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15465 13ded71a10168efaf05bd4227df87fef 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.4E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS15465 13ded71a10168efaf05bd4227df87fef 293 Gene3D G3DSA:3.40.190.10 178 254 3.3E-18 T 05-07-2017 K08M4_RS15465 13ded71a10168efaf05bd4227df87fef 293 SUPERFAMILY SSF53850 91 291 1.36E-39 T 05-07-2017 K08M4_RS02800 ba8924df7b85db9cbd0e0009cd2f8783 140 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 11 31 - T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS02800 ba8924df7b85db9cbd0e0009cd2f8783 140 Pfam PF00114 Pilin (bacterial filament) 41 126 3.8E-11 T 05-07-2017 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 K08M4_RS02800 ba8924df7b85db9cbd0e0009cd2f8783 140 PRINTS PR00813 Bacterial general secretion pathway protein G signature 12 37 1.9E-9 T 05-07-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 K08M4_RS02800 ba8924df7b85db9cbd0e0009cd2f8783 140 PRINTS PR00813 Bacterial general secretion pathway protein G signature 48 66 1.9E-9 T 05-07-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 K08M4_RS02800 ba8924df7b85db9cbd0e0009cd2f8783 140 Pfam PF13633 Prokaryotic N-terminal methylation site 10 36 1.0E-12 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS02800 ba8924df7b85db9cbd0e0009cd2f8783 140 SUPERFAMILY SSF54523 13 125 4.97E-23 T 05-07-2017 K08M4_RS02800 ba8924df7b85db9cbd0e0009cd2f8783 140 Gene3D G3DSA:3.30.700.10 13 125 4.8E-27 T 05-07-2017 K08M4_RS02800 ba8924df7b85db9cbd0e0009cd2f8783 140 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 33 1.4E-10 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS18400 2eabd60935383a9888e3d1ade9a33b38 706 ProSitePatterns PS00850 Glycine radical domain signature. 676 684 - T 05-07-2017 IPR019777 Formate C-acetyltransferase glycine radical, conserved site K08M4_RS18400 2eabd60935383a9888e3d1ade9a33b38 706 Gene3D G3DSA:3.20.70.20 125 685 2.3E-183 T 05-07-2017 K08M4_RS18400 2eabd60935383a9888e3d1ade9a33b38 706 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 116 705 1.2E-181 T 05-07-2017 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 K08M4_RS18400 2eabd60935383a9888e3d1ade9a33b38 706 SUPERFAMILY SSF51998 121 687 4.17E-189 T 05-07-2017 K08M4_RS18400 2eabd60935383a9888e3d1ade9a33b38 706 Pfam PF03477 ATP cone domain 4 89 1.9E-21 T 05-07-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 K08M4_RS18400 2eabd60935383a9888e3d1ade9a33b38 706 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 115 705 8.7E-199 T 05-07-2017 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 K08M4_RS14540 6ffbbac4b102b5024a61566e7435aa3c 259 Pfam PF04445 Putative SAM-dependent methyltransferase 19 255 3.1E-105 T 05-07-2017 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 K08M4_RS14540 6ffbbac4b102b5024a61566e7435aa3c 259 SUPERFAMILY SSF53335 5 255 2.82E-73 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS14540 6ffbbac4b102b5024a61566e7435aa3c 259 Hamap MF_01523 Ribosomal RNA small subunit methyltransferase J [rsmJ]. 3 256 38.224 T 05-07-2017 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 K08M4_RS14540 6ffbbac4b102b5024a61566e7435aa3c 259 Gene3D G3DSA:3.40.50.150 57 256 2.3E-75 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS14540 6ffbbac4b102b5024a61566e7435aa3c 259 Gene3D G3DSA:3.40.1630.10 2 56 5.1E-26 T 05-07-2017 K08M4_RS21650 eb8df7c37afff6600a70a6311f5539cd 224 SUPERFAMILY SSF52172 2 118 1.85E-35 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS21650 eb8df7c37afff6600a70a6311f5539cd 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 222 7.0E-26 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS21650 eb8df7c37afff6600a70a6311f5539cd 224 Gene3D G3DSA:1.10.10.10 124 223 7.2E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21650 eb8df7c37afff6600a70a6311f5539cd 224 Gene3D G3DSA:3.40.50.2300 2 123 4.6E-36 T 05-07-2017 K08M4_RS21650 eb8df7c37afff6600a70a6311f5539cd 224 SMART SM00862 147 222 2.7E-25 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS21650 eb8df7c37afff6600a70a6311f5539cd 224 Pfam PF00072 Response regulator receiver domain 3 112 3.7E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS21650 eb8df7c37afff6600a70a6311f5539cd 224 SUPERFAMILY SSF46894 121 222 5.39E-28 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS21650 eb8df7c37afff6600a70a6311f5539cd 224 SMART SM00448 1 112 3.7E-35 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS04455 ceabebe1c85d7f0f1b519ba37948f530 306 Gene3D G3DSA:3.40.190.10 85 167 1.4E-9 T 05-07-2017 K08M4_RS04455 ceabebe1c85d7f0f1b519ba37948f530 306 SUPERFAMILY SSF53850 83 291 1.14E-44 T 05-07-2017 K08M4_RS04455 ceabebe1c85d7f0f1b519ba37948f530 306 SUPERFAMILY SSF46785 2 106 1.02E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS04455 ceabebe1c85d7f0f1b519ba37948f530 306 Gene3D G3DSA:3.40.190.10 168 255 1.3E-21 T 05-07-2017 K08M4_RS04455 ceabebe1c85d7f0f1b519ba37948f530 306 Pfam PF03466 LysR substrate binding domain 83 288 7.9E-43 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS04455 ceabebe1c85d7f0f1b519ba37948f530 306 Gene3D G3DSA:1.10.10.10 3 79 6.2E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS04455 ceabebe1c85d7f0f1b519ba37948f530 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 56 1.0E-15 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19690 172621b7e8c193d567dca08c034fd43b 317 Gene3D G3DSA:1.10.3470.10 5 314 3.2E-73 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS19690 172621b7e8c193d567dca08c034fd43b 317 Pfam PF01032 FecCD transport family 11 312 4.9E-73 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 K08M4_RS19690 172621b7e8c193d567dca08c034fd43b 317 SUPERFAMILY SSF81345 5 312 3.14E-67 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS19135 99615429a014f1c889a03d74265fa1a6 298 Pfam PF04545 Sigma-70, region 4 236 290 2.1E-9 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS19135 99615429a014f1c889a03d74265fa1a6 298 Pfam PF00140 Sigma-70 factor, region 1.2 30 59 2.2E-7 T 05-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS19135 99615429a014f1c889a03d74265fa1a6 298 PIRSF PIRSF000770 18 295 5.9E-33 T 05-07-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 K08M4_RS19135 99615429a014f1c889a03d74265fa1a6 298 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 92 105 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS19135 99615429a014f1c889a03d74265fa1a6 298 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 61 292 1.0E-34 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS19135 99615429a014f1c889a03d74265fa1a6 298 PRINTS PR00046 Major sigma-70 factor signature 116 124 7.5E-14 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS19135 99615429a014f1c889a03d74265fa1a6 298 PRINTS PR00046 Major sigma-70 factor signature 277 288 7.5E-14 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS19135 99615429a014f1c889a03d74265fa1a6 298 PRINTS PR00046 Major sigma-70 factor signature 92 105 7.5E-14 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS19135 99615429a014f1c889a03d74265fa1a6 298 PRINTS PR00046 Major sigma-70 factor signature 239 251 7.5E-14 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS19135 99615429a014f1c889a03d74265fa1a6 298 SUPERFAMILY SSF88946 28 138 5.97E-38 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS19135 99615429a014f1c889a03d74265fa1a6 298 Pfam PF04542 Sigma-70 region 2 65 128 8.5E-16 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS19135 99615429a014f1c889a03d74265fa1a6 298 SUPERFAMILY SSF88659 199 293 7.48E-16 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS19135 99615429a014f1c889a03d74265fa1a6 298 Gene3D G3DSA:1.10.601.10 23 136 3.9E-44 T 05-07-2017 K08M4_RS19135 99615429a014f1c889a03d74265fa1a6 298 Gene3D G3DSA:1.10.10.10 230 293 8.2E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS07015 a71e42720744a91f6ede3f98be874d52 126 Gene3D G3DSA:3.40.50.10600 1 124 2.1E-39 T 05-07-2017 IPR021866 SpoIIAA-like K08M4_RS07015 a71e42720744a91f6ede3f98be874d52 126 SUPERFAMILY SSF52091 1 124 1.49E-36 T 05-07-2017 IPR002645 STAS domain K08M4_RS07015 a71e42720744a91f6ede3f98be874d52 126 Pfam PF11964 SpoIIAA-like 20 124 4.6E-19 T 05-07-2017 IPR021866 SpoIIAA-like K08M4_RS10395 8c120cc7a877970b7cafda922168c93a 432 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 158 237 1.6E-12 T 05-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 K08M4_RS10395 8c120cc7a877970b7cafda922168c93a 432 SUPERFAMILY SSF102735 1 131 1.57E-41 T 05-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 K08M4_RS10395 8c120cc7a877970b7cafda922168c93a 432 Hamap MF_00303 Trigger factor [tig]. 1 417 21.612 T 05-07-2017 IPR005215 Trigger factor GO:0015031 K08M4_RS10395 8c120cc7a877970b7cafda922168c93a 432 PIRSF PIRSF003095 1 432 2.9E-127 T 05-07-2017 IPR005215 Trigger factor GO:0015031 K08M4_RS10395 8c120cc7a877970b7cafda922168c93a 432 Gene3D G3DSA:3.30.70.1050 1 118 1.4E-40 T 05-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 K08M4_RS10395 8c120cc7a877970b7cafda922168c93a 432 Gene3D G3DSA:3.10.50.40 153 214 2.7E-6 T 05-07-2017 K08M4_RS10395 8c120cc7a877970b7cafda922168c93a 432 SUPERFAMILY SSF54534 91 241 2.36E-36 T 05-07-2017 K08M4_RS10395 8c120cc7a877970b7cafda922168c93a 432 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 262 411 1.7E-39 T 05-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 K08M4_RS10395 8c120cc7a877970b7cafda922168c93a 432 Gene3D G3DSA:1.10.3120.10 215 387 4.3E-60 T 05-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 K08M4_RS10395 8c120cc7a877970b7cafda922168c93a 432 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 6.2E-43 T 05-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 K08M4_RS10395 8c120cc7a877970b7cafda922168c93a 432 TIGRFAM TIGR00115 tig: trigger factor 11 411 2.0E-142 T 05-07-2017 IPR005215 Trigger factor GO:0015031 K08M4_RS10395 8c120cc7a877970b7cafda922168c93a 432 SUPERFAMILY SSF109998 248 428 2.45E-48 T 05-07-2017 IPR027304 Trigger factor/SurA domain K08M4_RS17115 64c05054f22036678498f6efcdd5d5c2 640 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 12 302 8.0E-74 T 05-07-2017 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 K08M4_RS17115 64c05054f22036678498f6efcdd5d5c2 640 Pfam PF00999 Sodium/hydrogen exchanger family 10 389 5.9E-57 T 05-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 K08M4_RS17115 64c05054f22036678498f6efcdd5d5c2 640 Pfam PF02254 TrkA-N domain 421 533 1.3E-21 T 05-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 K08M4_RS17115 64c05054f22036678498f6efcdd5d5c2 640 Gene3D G3DSA:3.40.50.720 416 550 2.6E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS17115 64c05054f22036678498f6efcdd5d5c2 640 SUPERFAMILY SSF51735 420 548 1.14E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS03880 2b44ef5a40c2984a4ed82fa4108c1983 146 Pfam PF04214 Protein of unknown function, DUF 48 117 1.2E-32 T 05-07-2017 IPR007332 Protein of unknown function DUF411 K08M4_RS02805 9512be2ea3e4d5813f377acbe6c44065 296 Gene3D G3DSA:3.20.20.70 150 283 1.2E-58 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS02805 9512be2ea3e4d5813f377acbe6c44065 296 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 41 127 4.1E-26 T 05-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 K08M4_RS02805 9512be2ea3e4d5813f377acbe6c44065 296 SUPERFAMILY SSF54675 13 128 1.81E-31 T 05-07-2017 K08M4_RS02805 9512be2ea3e4d5813f377acbe6c44065 296 SUPERFAMILY SSF51690 130 294 7.85E-59 T 05-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 K08M4_RS02805 9512be2ea3e4d5813f377acbe6c44065 296 Gene3D G3DSA:3.90.1170.20 17 149 4.3E-50 T 05-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 K08M4_RS02805 9512be2ea3e4d5813f377acbe6c44065 296 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 26 294 2.1E-93 T 05-07-2017 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 K08M4_RS02805 9512be2ea3e4d5813f377acbe6c44065 296 PIRSF PIRSF006250 16 296 2.9E-99 T 05-07-2017 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 K08M4_RS02805 9512be2ea3e4d5813f377acbe6c44065 296 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 130 293 2.1E-57 T 05-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 K08M4_RS12645 5e6c06380d091f4b4f9c69c25058f9c3 164 Pfam PF04386 Stringent starvation protein B 9 164 2.9E-41 T 05-07-2017 IPR007481 Stringent starvation protein B K08M4_RS12645 5e6c06380d091f4b4f9c69c25058f9c3 164 SUPERFAMILY SSF101738 4 117 2.09E-48 T 05-07-2017 IPR007481 Stringent starvation protein B K08M4_RS12645 5e6c06380d091f4b4f9c69c25058f9c3 164 Gene3D G3DSA:2.30.30.220 4 110 1.8E-51 T 05-07-2017 IPR007481 Stringent starvation protein B K08M4_RS12645 5e6c06380d091f4b4f9c69c25058f9c3 164 PIRSF PIRSF005276 3 164 2.3E-60 T 05-07-2017 IPR007481 Stringent starvation protein B K08M4_RS10160 fe8ad6964977f0c688821722f4b70c93 308 Gene3D G3DSA:3.90.550.10 3 240 2.5E-52 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS10160 fe8ad6964977f0c688821722f4b70c93 308 SUPERFAMILY SSF53448 3 223 8.84E-55 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS10160 fe8ad6964977f0c688821722f4b70c93 308 Pfam PF00535 Glycosyl transferase family 2 5 112 5.6E-30 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 K08M4_RS05270 4d59405cbed967eb081461e98e927e6d 256 SUPERFAMILY SSF52540 7 251 1.65E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05270 4d59405cbed967eb081461e98e927e6d 256 PIRSF PIRSF039085 3 256 7.2E-117 T 05-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 K08M4_RS05270 4d59405cbed967eb081461e98e927e6d 256 Gene3D G3DSA:3.40.50.300 6 253 7.8E-80 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05270 4d59405cbed967eb081461e98e927e6d 256 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS05270 4d59405cbed967eb081461e98e927e6d 256 Pfam PF00005 ABC transporter 22 181 3.1E-32 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS05270 4d59405cbed967eb081461e98e927e6d 256 SMART SM00382 31 229 1.3E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS13930 e3993be50fa7fd2baf549a504941d8a2 313 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 312 1.1E-126 T 05-07-2017 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 K08M4_RS13930 e3993be50fa7fd2baf549a504941d8a2 313 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 313 54.509 T 05-07-2017 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 K08M4_RS13930 e3993be50fa7fd2baf549a504941d8a2 313 Gene3D G3DSA:3.90.25.10 177 294 1.1E-37 T 05-07-2017 K08M4_RS13930 e3993be50fa7fd2baf549a504941d8a2 313 Gene3D G3DSA:3.40.50.720 2 176 2.9E-20 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13930 e3993be50fa7fd2baf549a504941d8a2 313 SUPERFAMILY SSF51735 1 309 4.38E-58 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13930 e3993be50fa7fd2baf549a504941d8a2 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 241 4.7E-45 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 K08M4_RS00450 8888764ef11b0328987db27ae5dc57ba 826 Gene3D G3DSA:3.30.70.270 416 573 1.1E-12 T 05-07-2017 K08M4_RS00450 8888764ef11b0328987db27ae5dc57ba 826 SMART SM00267 404 578 0.0035 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS00450 8888764ef11b0328987db27ae5dc57ba 826 Pfam PF00563 EAL domain 597 822 3.0E-59 T 05-07-2017 IPR001633 EAL domain K08M4_RS00450 8888764ef11b0328987db27ae5dc57ba 826 SMART SM00052 589 826 6.6E-39 T 05-07-2017 IPR001633 EAL domain K08M4_RS00450 8888764ef11b0328987db27ae5dc57ba 826 SUPERFAMILY SSF141868 597 823 1.01E-57 T 05-07-2017 IPR001633 EAL domain K08M4_RS00450 8888764ef11b0328987db27ae5dc57ba 826 SMART SM01204 217 343 1.9E-14 T 05-07-2017 IPR019494 FIST, C-domain K08M4_RS00450 8888764ef11b0328987db27ae5dc57ba 826 Gene3D G3DSA:3.20.20.450 598 823 1.5E-58 T 05-07-2017 IPR001633 EAL domain K08M4_RS00450 8888764ef11b0328987db27ae5dc57ba 826 SUPERFAMILY SSF55073 420 573 3.69E-12 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS00450 8888764ef11b0328987db27ae5dc57ba 826 Pfam PF10442 FIST C domain 219 341 2.6E-9 T 05-07-2017 IPR019494 FIST, C-domain K08M4_RS00450 8888764ef11b0328987db27ae5dc57ba 826 Pfam PF08495 FIST N domain 30 215 3.4E-24 T 05-07-2017 IPR013702 FIST domain, N-terminal K08M4_RS00450 8888764ef11b0328987db27ae5dc57ba 826 SMART SM00897 27 216 1.7E-14 T 05-07-2017 IPR013702 FIST domain, N-terminal K08M4_RS00450 8888764ef11b0328987db27ae5dc57ba 826 Pfam PF00990 Diguanylate cyclase, GGDEF domain 416 563 1.6E-8 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS05625 4a1b07d6c5d7364eb16b435fe3f115ef 343 Gene3D G3DSA:3.40.50.720 113 234 1.1E-14 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS05625 4a1b07d6c5d7364eb16b435fe3f115ef 343 Pfam PF07885 Ion channel 28 100 2.6E-12 T 05-07-2017 IPR013099 Potassium channel domain K08M4_RS05625 4a1b07d6c5d7364eb16b435fe3f115ef 343 SUPERFAMILY SSF81324 8 131 5.23E-17 T 05-07-2017 K08M4_RS05625 4a1b07d6c5d7364eb16b435fe3f115ef 343 Gene3D G3DSA:1.10.287.70 6 101 2.5E-15 T 05-07-2017 K08M4_RS05625 4a1b07d6c5d7364eb16b435fe3f115ef 343 SUPERFAMILY SSF51735 121 241 7.97E-12 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13070 10e1b18a73f7c92530c50b5cecb0a6a4 459 SUPERFAMILY SSF88723 105 162 4.32E-14 T 05-07-2017 IPR029060 PIN domain-like K08M4_RS13070 10e1b18a73f7c92530c50b5cecb0a6a4 459 SUPERFAMILY SSF88723 7 68 4.32E-14 T 05-07-2017 IPR029060 PIN domain-like K08M4_RS13070 10e1b18a73f7c92530c50b5cecb0a6a4 459 SMART SM00670 7 142 1.8E-11 T 05-07-2017 IPR002716 PIN domain K08M4_RS13070 10e1b18a73f7c92530c50b5cecb0a6a4 459 Pfam PF02562 PhoH-like protein 249 454 3.5E-54 T 05-07-2017 IPR003714 PhoH-like protein GO:0005524 K08M4_RS13070 10e1b18a73f7c92530c50b5cecb0a6a4 459 SUPERFAMILY SSF52540 248 438 2.75E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13070 10e1b18a73f7c92530c50b5cecb0a6a4 459 Gene3D G3DSA:3.40.50.1010 105 152 4.4E-15 T 05-07-2017 IPR029060 PIN domain-like K08M4_RS13070 10e1b18a73f7c92530c50b5cecb0a6a4 459 Gene3D G3DSA:3.40.50.1010 9 67 4.4E-15 T 05-07-2017 IPR029060 PIN domain-like K08M4_RS13070 10e1b18a73f7c92530c50b5cecb0a6a4 459 Gene3D G3DSA:3.40.50.300 246 457 8.8E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13070 10e1b18a73f7c92530c50b5cecb0a6a4 459 Pfam PF13638 PIN domain 9 151 3.9E-35 T 05-07-2017 IPR002716 PIN domain K08M4_RS13515 7c5b1915d069313a9bfbdfcd6d0067c8 400 PRINTS PR00721 Stomatin signature 144 165 9.4E-8 T 05-07-2017 IPR001972 Stomatin family GO:0016020 K08M4_RS13515 7c5b1915d069313a9bfbdfcd6d0067c8 400 PRINTS PR00721 Stomatin signature 94 116 9.4E-8 T 05-07-2017 IPR001972 Stomatin family GO:0016020 K08M4_RS13515 7c5b1915d069313a9bfbdfcd6d0067c8 400 PRINTS PR00721 Stomatin signature 200 223 9.4E-8 T 05-07-2017 IPR001972 Stomatin family GO:0016020 K08M4_RS13515 7c5b1915d069313a9bfbdfcd6d0067c8 400 TIGRFAM TIGR01933 hflK: HflK protein 89 352 1.8E-115 T 05-07-2017 IPR010201 HflK GO:0016021 K08M4_RS13515 7c5b1915d069313a9bfbdfcd6d0067c8 400 Pfam PF12221 Bacterial membrane protein N terminal 1 56 2.3E-14 T 05-07-2017 IPR020980 Menbrane protein HflK, N-terminal K08M4_RS13515 7c5b1915d069313a9bfbdfcd6d0067c8 400 Pfam PF01145 SPFH domain / Band 7 family 91 265 2.2E-28 T 05-07-2017 IPR001107 Band 7 domain K08M4_RS13515 7c5b1915d069313a9bfbdfcd6d0067c8 400 SUPERFAMILY SSF117892 140 255 4.45E-22 T 05-07-2017 IPR001107 Band 7 domain K08M4_RS13515 7c5b1915d069313a9bfbdfcd6d0067c8 400 SMART SM00244 87 250 1.3E-48 T 05-07-2017 IPR001107 Band 7 domain K08M4_RS03580 5759307d38286d11e4e53abf45a882db 676 Gene3D G3DSA:2.170.130.10 43 141 3.0E-21 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS03580 5759307d38286d11e4e53abf45a882db 676 Gene3D G3DSA:2.40.170.20 142 676 2.9E-64 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS03580 5759307d38286d11e4e53abf45a882db 676 Pfam PF07715 TonB-dependent Receptor Plug Domain 41 136 4.7E-18 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS03580 5759307d38286d11e4e53abf45a882db 676 Pfam PF00593 TonB dependent receptor 426 674 9.6E-22 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS03580 5759307d38286d11e4e53abf45a882db 676 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 659 676 - T 05-07-2017 IPR010917 TonB-dependent receptor, conserved site K08M4_RS03580 5759307d38286d11e4e53abf45a882db 676 SUPERFAMILY SSF56935 21 676 1.28E-87 T 05-07-2017 K08M4_RS09895 3771700278bd4b9bdbc4421bf4528f87 388 Pfam PF09002 Domain of unknown function (DUF1887) 1 379 2.3E-174 T 05-07-2017 IPR015093 Protein of unknown function DUF1887 K08M4_RS09895 3771700278bd4b9bdbc4421bf4528f87 388 Gene3D G3DSA:1.10.10.680 162 240 1.1E-52 T 05-07-2017 K08M4_RS09895 3771700278bd4b9bdbc4421bf4528f87 388 Gene3D G3DSA:3.40.50.10770 1 140 1.3E-62 T 05-07-2017 K08M4_RS09895 3771700278bd4b9bdbc4421bf4528f87 388 SUPERFAMILY SSF52980 1 382 1.02E-121 T 05-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 K08M4_RS09895 3771700278bd4b9bdbc4421bf4528f87 388 Gene3D G3DSA:3.40.1350.10 241 382 5.1E-59 T 05-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 Pfam PF00224 Pyruvate kinase, barrel domain 1 341 1.0E-152 T 05-07-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 Gene3D G3DSA:3.40.1380.20 327 468 6.4E-44 T 05-07-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 469 4.5E-185 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 SUPERFAMILY SSF52935 323 469 7.06E-34 T 05-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 05-07-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 SUPERFAMILY SSF51621 1 74 3.49E-101 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 SUPERFAMILY SSF51621 156 339 3.49E-101 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 SUPERFAMILY SSF50800 70 167 2.27E-28 T 05-07-2017 IPR011037 Pyruvate kinase-like, insert domain K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 Gene3D G3DSA:2.40.33.10 73 168 1.3E-31 T 05-07-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 468 2.7E-28 T 05-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 Gene3D G3DSA:3.20.20.60 169 326 4.1E-118 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 Gene3D G3DSA:3.20.20.60 2 72 4.1E-118 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 PRINTS PR01050 Pyruvate kinase family signature 217 243 3.5E-78 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 PRINTS PR01050 Pyruvate kinase family signature 186 200 3.5E-78 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 PRINTS PR01050 Pyruvate kinase family signature 244 268 3.5E-78 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 PRINTS PR01050 Pyruvate kinase family signature 294 312 3.5E-78 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 PRINTS PR01050 Pyruvate kinase family signature 313 329 3.5E-78 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 PRINTS PR01050 Pyruvate kinase family signature 59 75 3.5E-78 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS12860 9f6ea9dcdd2032e95ed4afaa41ff7dc9 470 PRINTS PR01050 Pyruvate kinase family signature 269 293 3.5E-78 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS02630 c71c3afe07f8cad1bf65222c55e95af9 393 SUPERFAMILY SSF53633 4 242 2.09E-72 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS02630 c71c3afe07f8cad1bf65222c55e95af9 393 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 05-07-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS02630 c71c3afe07f8cad1bf65222c55e95af9 393 Pfam PF00696 Amino acid kinase family 3 229 1.2E-51 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS02630 c71c3afe07f8cad1bf65222c55e95af9 393 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 377 4.0E-71 T 05-07-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS02630 c71c3afe07f8cad1bf65222c55e95af9 393 Gene3D G3DSA:3.40.1160.10 1 242 2.0E-69 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS00930 95acf0c704bfab7c2a28966918d5421a 149 ProSitePatterns PS01029 Dehydroquinase class II signature. 10 27 - T 05-07-2017 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 K08M4_RS00930 95acf0c704bfab7c2a28966918d5421a 149 SUPERFAMILY SSF52304 3 146 2.22E-62 T 05-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 K08M4_RS00930 95acf0c704bfab7c2a28966918d5421a 149 Gene3D G3DSA:3.40.50.9100 5 147 2.3E-68 T 05-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 K08M4_RS00930 95acf0c704bfab7c2a28966918d5421a 149 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 149 74.341 T 05-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 K08M4_RS00930 95acf0c704bfab7c2a28966918d5421a 149 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 6 145 3.0E-65 T 05-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 K08M4_RS00930 95acf0c704bfab7c2a28966918d5421a 149 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 21 137 9.0E-55 T 05-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 K08M4_RS00930 95acf0c704bfab7c2a28966918d5421a 149 PIRSF PIRSF001399 3 149 1.4E-60 T 05-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 K08M4_RS00930 95acf0c704bfab7c2a28966918d5421a 149 Pfam PF01220 Dehydroquinase class II 6 142 6.2E-60 T 05-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 K08M4_RS15205 ba0d9656c1db6ce3fe394f1951b29d74 575 Gene3D G3DSA:3.50.50.60 480 545 1.3E-117 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS15205 ba0d9656c1db6ce3fe394f1951b29d74 575 Gene3D G3DSA:3.50.50.60 2 126 1.3E-117 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS15205 ba0d9656c1db6ce3fe394f1951b29d74 575 Gene3D G3DSA:3.50.50.60 189 328 1.3E-117 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS15205 ba0d9656c1db6ce3fe394f1951b29d74 575 Pfam PF05199 GMC oxidoreductase 401 539 2.9E-40 T 05-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 K08M4_RS15205 ba0d9656c1db6ce3fe394f1951b29d74 575 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 82 105 - T 05-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 K08M4_RS15205 ba0d9656c1db6ce3fe394f1951b29d74 575 SUPERFAMILY SSF51905 486 546 5.18E-80 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS15205 ba0d9656c1db6ce3fe394f1951b29d74 575 SUPERFAMILY SSF51905 1 303 5.18E-80 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS15205 ba0d9656c1db6ce3fe394f1951b29d74 575 PIRSF PIRSF000137 1 554 4.7E-140 T 05-07-2017 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 K08M4_RS15205 ba0d9656c1db6ce3fe394f1951b29d74 575 TIGRFAM TIGR01810 betA: choline dehydrogenase 6 547 1.1E-233 T 05-07-2017 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 K08M4_RS15205 ba0d9656c1db6ce3fe394f1951b29d74 575 Hamap MF_00750 Oxygen-dependent choline dehydrogenase [betA]. 3 566 59.16 T 05-07-2017 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 K08M4_RS15205 ba0d9656c1db6ce3fe394f1951b29d74 575 SUPERFAMILY SSF54373 305 486 1.28E-60 T 05-07-2017 K08M4_RS15205 ba0d9656c1db6ce3fe394f1951b29d74 575 Pfam PF00732 GMC oxidoreductase 5 310 2.9E-87 T 05-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 K08M4_RS01170 1e6f05c1c98cace5408554ef08ee3103 393 Gene3D G3DSA:3.90.1150.10 250 384 9.9E-49 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS01170 1e6f05c1c98cace5408554ef08ee3103 393 SUPERFAMILY SSF53383 9 383 7.83E-113 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS01170 1e6f05c1c98cace5408554ef08ee3103 393 PIRSF PIRSF001434 1 385 1.1E-126 T 05-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 K08M4_RS01170 1e6f05c1c98cace5408554ef08ee3103 393 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 382 1.6E-131 T 05-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 K08M4_RS01170 1e6f05c1c98cace5408554ef08ee3103 393 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 191 205 - T 05-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 K08M4_RS01170 1e6f05c1c98cace5408554ef08ee3103 393 Gene3D G3DSA:3.40.640.10 5 247 6.3E-81 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS01170 1e6f05c1c98cace5408554ef08ee3103 393 TIGRFAM TIGR02080 O_succ_thio_ly: O-succinylhomoserine (thiol)-lyase 4 383 4.9E-195 T 05-07-2017 IPR011821 O-succinylhomoserine (thiol)-lyase KEGG: 00270+2.5.1.48|KEGG: 00450+2.5.1.48|KEGG: 00920+2.5.1.48 K08M4_RS11345 c0516ccc6a5015d76b181c2af00cb469 416 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 05-07-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 K08M4_RS11345 c0516ccc6a5015d76b181c2af00cb469 416 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 416 52.149 T 05-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 K08M4_RS11345 c0516ccc6a5015d76b181c2af00cb469 416 Gene3D G3DSA:3.90.1150.10 284 415 1.4E-52 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS11345 c0516ccc6a5015d76b181c2af00cb469 416 SUPERFAMILY SSF53383 6 415 9.52E-183 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS11345 c0516ccc6a5015d76b181c2af00cb469 416 Gene3D G3DSA:3.40.640.10 37 283 7.7E-111 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS11345 c0516ccc6a5015d76b181c2af00cb469 416 Pfam PF00464 Serine hydroxymethyltransferase 9 385 1.1E-180 T 05-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 K08M4_RS11345 c0516ccc6a5015d76b181c2af00cb469 416 PIRSF PIRSF000412 1 415 2.5E-167 T 05-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 K08M4_RS06220 f7c8a4b3f88b52fc80063f006b8a8ae6 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 77 5.6E-18 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS06220 f7c8a4b3f88b52fc80063f006b8a8ae6 240 SUPERFAMILY SSF46785 10 91 5.79E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06220 f7c8a4b3f88b52fc80063f006b8a8ae6 240 SMART SM00345 18 77 4.0E-17 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS06220 f7c8a4b3f88b52fc80063f006b8a8ae6 240 Gene3D G3DSA:1.20.120.530 104 234 2.6E-20 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS06220 f7c8a4b3f88b52fc80063f006b8a8ae6 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 1.2E-8 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS06220 f7c8a4b3f88b52fc80063f006b8a8ae6 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 1.2E-8 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS06220 f7c8a4b3f88b52fc80063f006b8a8ae6 240 Gene3D G3DSA:1.10.10.10 9 86 1.8E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06220 f7c8a4b3f88b52fc80063f006b8a8ae6 240 Pfam PF07729 FCD domain 107 225 5.5E-20 T 05-07-2017 IPR011711 GntR, C-terminal K08M4_RS06220 f7c8a4b3f88b52fc80063f006b8a8ae6 240 SUPERFAMILY SSF48008 106 228 1.44E-19 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS06220 f7c8a4b3f88b52fc80063f006b8a8ae6 240 SMART SM00895 106 227 3.9E-14 T 05-07-2017 IPR011711 GntR, C-terminal K08M4_RS00985 bc2932458a270cfcd7e441110743d265 209 SUPERFAMILY SSF52172 4 168 2.57E-26 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS00985 bc2932458a270cfcd7e441110743d265 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 3.6E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS00985 bc2932458a270cfcd7e441110743d265 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 3.6E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS00985 bc2932458a270cfcd7e441110743d265 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 3.6E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS00985 bc2932458a270cfcd7e441110743d265 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS00985 bc2932458a270cfcd7e441110743d265 209 SMART SM00448 5 119 6.0E-21 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS00985 bc2932458a270cfcd7e441110743d265 209 Pfam PF00072 Response regulator receiver domain 7 119 3.2E-23 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS00985 bc2932458a270cfcd7e441110743d265 209 Gene3D G3DSA:3.40.50.2300 4 131 2.1E-28 T 05-07-2017 K08M4_RS00985 bc2932458a270cfcd7e441110743d265 209 SMART SM00421 147 204 4.3E-23 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS00985 bc2932458a270cfcd7e441110743d265 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 1.2E-19 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS00985 bc2932458a270cfcd7e441110743d265 209 Gene3D G3DSA:1.10.10.10 141 206 8.7E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19635 722ba1ef157c26eb096dbd5f3439617e 419 Gene3D G3DSA:3.90.770.10 51 151 1.1E-71 T 05-07-2017 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 K08M4_RS19635 722ba1ef157c26eb096dbd5f3439617e 419 Gene3D G3DSA:3.90.770.10 264 407 1.1E-71 T 05-07-2017 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 K08M4_RS19635 722ba1ef157c26eb096dbd5f3439617e 419 Gene3D G3DSA:3.30.70.420 152 261 1.2E-36 T 05-07-2017 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 K08M4_RS19635 722ba1ef157c26eb096dbd5f3439617e 419 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 81 102 1.2E-36 T 05-07-2017 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 K08M4_RS19635 722ba1ef157c26eb096dbd5f3439617e 419 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 112 132 1.2E-36 T 05-07-2017 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 K08M4_RS19635 722ba1ef157c26eb096dbd5f3439617e 419 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 201 219 1.2E-36 T 05-07-2017 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 K08M4_RS19635 722ba1ef157c26eb096dbd5f3439617e 419 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 242 267 1.2E-36 T 05-07-2017 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 K08M4_RS19635 722ba1ef157c26eb096dbd5f3439617e 419 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 291 317 1.2E-36 T 05-07-2017 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 K08M4_RS19635 722ba1ef157c26eb096dbd5f3439617e 419 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 344 365 1.2E-36 T 05-07-2017 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 K08M4_RS19635 722ba1ef157c26eb096dbd5f3439617e 419 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 53 419 4.3E-111 T 05-07-2017 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 K08M4_RS19635 722ba1ef157c26eb096dbd5f3439617e 419 SUPERFAMILY SSF56542 259 409 5.23E-77 T 05-07-2017 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 K08M4_RS19635 722ba1ef157c26eb096dbd5f3439617e 419 SUPERFAMILY SSF56542 24 143 5.23E-77 T 05-07-2017 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 K08M4_RS19635 722ba1ef157c26eb096dbd5f3439617e 419 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 356 363 - T 05-07-2017 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 K08M4_RS19635 722ba1ef157c26eb096dbd5f3439617e 419 SUPERFAMILY SSF55035 146 261 6.28E-36 T 05-07-2017 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 K08M4_RS12040 f2ede5032f3f45843f1d1aafe3857a7a 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 225 6.0E-28 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS12040 f2ede5032f3f45843f1d1aafe3857a7a 229 SMART SM00448 3 116 3.3E-45 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS12040 f2ede5032f3f45843f1d1aafe3857a7a 229 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 1 226 2.5E-112 T 05-07-2017 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 K08M4_RS12040 f2ede5032f3f45843f1d1aafe3857a7a 229 SUPERFAMILY SSF52172 3 183 9.67E-43 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS12040 f2ede5032f3f45843f1d1aafe3857a7a 229 Gene3D G3DSA:1.10.10.10 129 227 5.1E-36 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS12040 f2ede5032f3f45843f1d1aafe3857a7a 229 SMART SM00862 150 225 1.1E-26 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS12040 f2ede5032f3f45843f1d1aafe3857a7a 229 Gene3D G3DSA:3.40.50.2300 2 124 3.4E-41 T 05-07-2017 K08M4_RS12040 f2ede5032f3f45843f1d1aafe3857a7a 229 Pfam PF00072 Response regulator receiver domain 5 116 4.9E-29 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS11485 415850ad06b5a94af20df0c2d7e40a50 255 TIGRFAM TIGR01938 nqrC: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit 5 248 6.3E-95 T 05-07-2017 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 K08M4_RS11485 415850ad06b5a94af20df0c2d7e40a50 255 Hamap MF_00427 Na(+)-translocating NADH-quinone reductase subunit C [nqrC]. 6 252 35.879 T 05-07-2017 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 K08M4_RS11485 415850ad06b5a94af20df0c2d7e40a50 255 SMART SM00900 142 240 4.7E-32 T 05-07-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 K08M4_RS11485 415850ad06b5a94af20df0c2d7e40a50 255 PIRSF PIRSF009437 1 255 4.5E-105 T 05-07-2017 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 K08M4_RS11485 415850ad06b5a94af20df0c2d7e40a50 255 Pfam PF04205 FMN-binding domain 142 237 1.4E-14 T 05-07-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 K08M4_RS19090 91e8ee36a3407c6f909af28d43a30650 469 SUPERFAMILY SSF55874 339 455 1.31E-14 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS19090 91e8ee36a3407c6f909af28d43a30650 469 Pfam PF11884 Domain of unknown function (DUF3404) 15 263 5.6E-90 T 05-07-2017 IPR021821 Protein of unknown function DUF3404 K08M4_RS19090 91e8ee36a3407c6f909af28d43a30650 469 Gene3D G3DSA:1.10.287.130 259 318 3.7E-6 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS19090 91e8ee36a3407c6f909af28d43a30650 469 SUPERFAMILY SSF47384 260 319 2.35E-7 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS19090 91e8ee36a3407c6f909af28d43a30650 469 Gene3D G3DSA:3.30.565.10 342 450 3.9E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS19090 91e8ee36a3407c6f909af28d43a30650 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 450 3.6E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS19090 91e8ee36a3407c6f909af28d43a30650 469 SMART SM00388 261 328 4.9E-5 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS00970 c315384a255fc3b01782f270614a2c33 567 Pfam PF00474 Sodium:solute symporter family 33 299 1.6E-33 T 05-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 K08M4_RS00970 c315384a255fc3b01782f270614a2c33 567 Pfam PF00474 Sodium:solute symporter family 368 489 6.2E-19 T 05-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 K08M4_RS00970 c315384a255fc3b01782f270614a2c33 567 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 8 558 1.0E-261 T 05-07-2017 IPR019899 Sodium/solute symporter, VC2705 subfamily K08M4_RS03555 0e8ec9084541084b77b80ab19001dda9 482 SUPERFAMILY SSF52402 174 372 2.43E-39 T 05-07-2017 K08M4_RS03555 0e8ec9084541084b77b80ab19001dda9 482 TIGRFAM TIGR04271 ThiI_C_thiazole: thiazole biosynthesis domain 382 482 1.1E-42 T 05-07-2017 IPR026340 Thiazole biosynthesis domain GO:0052837 K08M4_RS03555 0e8ec9084541084b77b80ab19001dda9 482 Pfam PF02926 THUMP domain 51 158 3.5E-20 T 05-07-2017 IPR004114 THUMP domain GO:0003723 K08M4_RS03555 0e8ec9084541084b77b80ab19001dda9 482 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 4 377 9.5E-111 T 05-07-2017 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 K08M4_RS03555 0e8ec9084541084b77b80ab19001dda9 482 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 369 2.7E-68 T 05-07-2017 IPR020536 Thil, AANH domain GO:0004810 K08M4_RS03555 0e8ec9084541084b77b80ab19001dda9 482 SUPERFAMILY SSF52821 398 481 3.4E-12 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS03555 0e8ec9084541084b77b80ab19001dda9 482 Gene3D G3DSA:3.40.50.620 173 333 1.3E-32 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS03555 0e8ec9084541084b77b80ab19001dda9 482 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 482 223.23 T 05-07-2017 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 K08M4_RS03555 0e8ec9084541084b77b80ab19001dda9 482 Gene3D G3DSA:3.40.250.10 405 480 1.3E-10 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS03555 0e8ec9084541084b77b80ab19001dda9 482 SMART SM00981 76 165 4.5E-23 T 05-07-2017 IPR004114 THUMP domain GO:0003723 K08M4_RS03555 0e8ec9084541084b77b80ab19001dda9 482 SUPERFAMILY SSF143437 1 173 5.06E-47 T 05-07-2017 K08M4_RS14820 5032aa4d2cd71d40c922fc80eb1d967f 217 Pfam PF03006 Haemolysin-III related 13 207 2.3E-37 T 05-07-2017 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 K08M4_RS14820 5032aa4d2cd71d40c922fc80eb1d967f 217 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 13 213 7.0E-69 T 05-07-2017 IPR005744 Hly-III GO:0016021|GO:0019835 K08M4_RS04640 7bd4f9042b3b5102ac984bdcc5cf410d 525 SMART SM00098 27 435 3.4E-56 T 05-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 K08M4_RS04640 7bd4f9042b3b5102ac984bdcc5cf410d 525 PRINTS PR00113 Alkaline phosphatase signature 26 46 5.1E-38 T 05-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 K08M4_RS04640 7bd4f9042b3b5102ac984bdcc5cf410d 525 PRINTS PR00113 Alkaline phosphatase signature 122 142 5.1E-38 T 05-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 K08M4_RS04640 7bd4f9042b3b5102ac984bdcc5cf410d 525 PRINTS PR00113 Alkaline phosphatase signature 166 176 5.1E-38 T 05-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 K08M4_RS04640 7bd4f9042b3b5102ac984bdcc5cf410d 525 PRINTS PR00113 Alkaline phosphatase signature 267 296 5.1E-38 T 05-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 K08M4_RS04640 7bd4f9042b3b5102ac984bdcc5cf410d 525 PRINTS PR00113 Alkaline phosphatase signature 85 100 5.1E-38 T 05-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 K08M4_RS04640 7bd4f9042b3b5102ac984bdcc5cf410d 525 Gene3D G3DSA:3.40.720.10 466 523 5.3E-140 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 K08M4_RS04640 7bd4f9042b3b5102ac984bdcc5cf410d 525 Gene3D G3DSA:3.40.720.10 430 431 5.3E-140 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 K08M4_RS04640 7bd4f9042b3b5102ac984bdcc5cf410d 525 Gene3D G3DSA:3.40.720.10 7 373 5.3E-140 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 K08M4_RS04640 7bd4f9042b3b5102ac984bdcc5cf410d 525 ProSitePatterns PS00123 Alkaline phosphatase active site. 85 93 - T 05-07-2017 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 K08M4_RS04640 7bd4f9042b3b5102ac984bdcc5cf410d 525 SUPERFAMILY SSF53649 466 514 1.67E-115 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 K08M4_RS04640 7bd4f9042b3b5102ac984bdcc5cf410d 525 SUPERFAMILY SSF53649 10 401 1.67E-115 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 K08M4_RS04640 7bd4f9042b3b5102ac984bdcc5cf410d 525 Pfam PF00245 Alkaline phosphatase 26 503 2.4E-84 T 05-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 K08M4_RS17930 8b8558dfafcaf30dedbc54a447934fa6 171 ProSitePatterns PS00893 Nudix box signature. 68 89 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 K08M4_RS17930 8b8558dfafcaf30dedbc54a447934fa6 171 Gene3D G3DSA:3.90.79.10 2 167 3.6E-48 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS17930 8b8558dfafcaf30dedbc54a447934fa6 171 Pfam PF00293 NUDIX domain 33 148 1.1E-17 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 K08M4_RS17930 8b8558dfafcaf30dedbc54a447934fa6 171 SUPERFAMILY SSF55811 2 168 2.03E-42 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS02290 56f411a81259cf9d0d5fb36ad87c38dd 664 Gene3D G3DSA:3.40.50.970 327 533 2.3E-80 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS02290 56f411a81259cf9d0d5fb36ad87c38dd 664 TIGRFAM TIGR00232 tktlase_bact: transketolase 5 663 0.0 T 05-07-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 K08M4_RS02290 56f411a81259cf9d0d5fb36ad87c38dd 664 Gene3D G3DSA:3.40.50.920 538 663 2.7E-51 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 K08M4_RS02290 56f411a81259cf9d0d5fb36ad87c38dd 664 ProSitePatterns PS00801 Transketolase signature 1. 12 32 - T 05-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS02290 56f411a81259cf9d0d5fb36ad87c38dd 664 SUPERFAMILY SSF52518 333 526 1.02E-67 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS02290 56f411a81259cf9d0d5fb36ad87c38dd 664 SUPERFAMILY SSF52922 533 664 3.4E-45 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 K08M4_RS02290 56f411a81259cf9d0d5fb36ad87c38dd 664 ProSitePatterns PS00802 Transketolase signature 2. 467 483 - T 05-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS02290 56f411a81259cf9d0d5fb36ad87c38dd 664 SUPERFAMILY SSF52518 6 329 2.56E-118 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS02290 56f411a81259cf9d0d5fb36ad87c38dd 664 Pfam PF02780 Transketolase, C-terminal domain 540 655 6.3E-20 T 05-07-2017 IPR033248 Transketolase, C-terminal domain K08M4_RS02290 56f411a81259cf9d0d5fb36ad87c38dd 664 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 4 333 5.6E-165 T 05-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS02290 56f411a81259cf9d0d5fb36ad87c38dd 664 Pfam PF02779 Transketolase, pyrimidine binding domain 354 524 2.2E-47 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain K08M4_RS02290 56f411a81259cf9d0d5fb36ad87c38dd 664 Gene3D G3DSA:3.40.50.970 5 321 1.9E-132 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS02290 56f411a81259cf9d0d5fb36ad87c38dd 664 SMART SM00861 354 525 2.8E-67 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain K08M4_RS06535 1e9efbb82aa7c66da4192ab3260d65e9 457 PRINTS PR00173 Glutamate-aspartate symporter signature 105 130 1.9E-29 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS06535 1e9efbb82aa7c66da4192ab3260d65e9 457 PRINTS PR00173 Glutamate-aspartate symporter signature 369 388 1.9E-29 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS06535 1e9efbb82aa7c66da4192ab3260d65e9 457 PRINTS PR00173 Glutamate-aspartate symporter signature 396 416 1.9E-29 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS06535 1e9efbb82aa7c66da4192ab3260d65e9 457 PRINTS PR00173 Glutamate-aspartate symporter signature 181 203 1.9E-29 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS06535 1e9efbb82aa7c66da4192ab3260d65e9 457 PRINTS PR00173 Glutamate-aspartate symporter signature 259 278 1.9E-29 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS06535 1e9efbb82aa7c66da4192ab3260d65e9 457 PRINTS PR00173 Glutamate-aspartate symporter signature 75 95 1.9E-29 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS06535 1e9efbb82aa7c66da4192ab3260d65e9 457 PRINTS PR00173 Glutamate-aspartate symporter signature 27 47 1.9E-29 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS06535 1e9efbb82aa7c66da4192ab3260d65e9 457 Gene3D G3DSA:1.10.3860.10 22 448 1.0E-95 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS06535 1e9efbb82aa7c66da4192ab3260d65e9 457 SUPERFAMILY SSF118215 29 441 1.83E-90 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS06535 1e9efbb82aa7c66da4192ab3260d65e9 457 Pfam PF00375 Sodium:dicarboxylate symporter family 32 441 2.4E-98 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS10405 9702e5612d69801e07de52ed0f970c0b 449 Gene3D G3DSA:3.40.50.2300 2 134 1.1E-29 T 05-07-2017 K08M4_RS10405 9702e5612d69801e07de52ed0f970c0b 449 SMART SM00382 164 307 7.8E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS10405 9702e5612d69801e07de52ed0f970c0b 449 SMART SM00448 2 114 7.0E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS10405 9702e5612d69801e07de52ed0f970c0b 449 Pfam PF00072 Response regulator receiver domain 5 113 9.8E-24 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS10405 9702e5612d69801e07de52ed0f970c0b 449 SUPERFAMILY SSF52540 144 374 9.52E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10405 9702e5612d69801e07de52ed0f970c0b 449 Pfam PF00158 Sigma-54 interaction domain 144 310 2.0E-69 T 05-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 K08M4_RS10405 9702e5612d69801e07de52ed0f970c0b 449 Gene3D G3DSA:1.10.8.60 317 368 2.8E-22 T 05-07-2017 K08M4_RS10405 9702e5612d69801e07de52ed0f970c0b 449 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 357 366 - T 05-07-2017 IPR025944 Sigma-54 interaction domain, conserved site K08M4_RS10405 9702e5612d69801e07de52ed0f970c0b 449 Pfam PF02954 Bacterial regulatory protein, Fis family 398 437 1.7E-7 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS10405 9702e5612d69801e07de52ed0f970c0b 449 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 168 181 - T 05-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 K08M4_RS10405 9702e5612d69801e07de52ed0f970c0b 449 Gene3D G3DSA:1.10.10.60 369 439 9.5E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS10405 9702e5612d69801e07de52ed0f970c0b 449 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 230 245 - T 05-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 K08M4_RS10405 9702e5612d69801e07de52ed0f970c0b 449 Gene3D G3DSA:3.40.50.300 143 316 2.3E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10405 9702e5612d69801e07de52ed0f970c0b 449 SUPERFAMILY SSF46689 357 439 8.96E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS10405 9702e5612d69801e07de52ed0f970c0b 449 SUPERFAMILY SSF52172 2 188 9.82E-37 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS09735 43fea59ffbd7810e3b0f587d5c4318f2 374 Gene3D G3DSA:3.40.50.1770 204 359 1.2E-29 T 05-07-2017 K08M4_RS09735 43fea59ffbd7810e3b0f587d5c4318f2 374 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 2.1E-83 T 05-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain K08M4_RS09735 43fea59ffbd7810e3b0f587d5c4318f2 374 SMART SM01002 149 297 2.9E-87 T 05-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain K08M4_RS09735 43fea59ffbd7810e3b0f587d5c4318f2 374 SUPERFAMILY SSF52283 305 360 8.5E-67 T 05-07-2017 K08M4_RS09735 43fea59ffbd7810e3b0f587d5c4318f2 374 SUPERFAMILY SSF52283 1 137 8.5E-67 T 05-07-2017 K08M4_RS09735 43fea59ffbd7810e3b0f587d5c4318f2 374 PIRSF PIRSF000183 1 371 2.7E-156 T 05-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 K08M4_RS09735 43fea59ffbd7810e3b0f587d5c4318f2 374 SMART SM01003 4 137 7.0E-79 T 05-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal K08M4_RS09735 43fea59ffbd7810e3b0f587d5c4318f2 374 Gene3D G3DSA:3.40.50.1770 3 178 5.6E-62 T 05-07-2017 K08M4_RS09735 43fea59ffbd7810e3b0f587d5c4318f2 374 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 7.4E-155 T 05-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 K08M4_RS09735 43fea59ffbd7810e3b0f587d5c4318f2 374 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 3.8E-46 T 05-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal K08M4_RS09735 43fea59ffbd7810e3b0f587d5c4318f2 374 Gene3D G3DSA:3.50.50.60 179 203 3.3E-8 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS09735 43fea59ffbd7810e3b0f587d5c4318f2 374 SUPERFAMILY SSF51735 137 303 5.19E-49 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS15185 034fef7714f69adcbeed39266459f20f 234 SUPERFAMILY SSF46894 134 229 2.41E-22 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS15185 034fef7714f69adcbeed39266459f20f 234 SUPERFAMILY SSF52172 2 126 5.27E-34 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS15185 034fef7714f69adcbeed39266459f20f 234 Gene3D G3DSA:1.10.10.10 130 229 1.8E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15185 034fef7714f69adcbeed39266459f20f 234 SMART SM00862 152 228 3.3E-18 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS15185 034fef7714f69adcbeed39266459f20f 234 Gene3D G3DSA:3.40.50.2300 2 123 5.6E-34 T 05-07-2017 K08M4_RS15185 034fef7714f69adcbeed39266459f20f 234 Pfam PF00072 Response regulator receiver domain 7 114 1.3E-22 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS15185 034fef7714f69adcbeed39266459f20f 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 228 3.4E-18 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS15185 034fef7714f69adcbeed39266459f20f 234 SMART SM00448 4 114 1.3E-33 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS19415 f6aff5fe7801f24cfe9c2d0acfb38efb 340 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 157 337 3.0E-27 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS19415 f6aff5fe7801f24cfe9c2d0acfb38efb 340 SUPERFAMILY SSF161098 134 321 3.27E-19 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS19415 f6aff5fe7801f24cfe9c2d0acfb38efb 340 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 5 49 1.3E-8 T 05-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain K08M4_RS19415 f6aff5fe7801f24cfe9c2d0acfb38efb 340 Gene3D G3DSA:1.10.3720.10 130 336 4.5E-19 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS06060 202dc61e64a4a9243609b29eaad2be68 237 Gene3D G3DSA:1.10.10.10 2 74 4.4E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06060 202dc61e64a4a9243609b29eaad2be68 237 SUPERFAMILY SSF64288 96 232 4.24E-37 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain K08M4_RS06060 202dc61e64a4a9243609b29eaad2be68 237 Gene3D G3DSA:3.40.1410.10 89 225 1.6E-45 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain K08M4_RS06060 202dc61e64a4a9243609b29eaad2be68 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 69 8.8E-16 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS06060 202dc61e64a4a9243609b29eaad2be68 237 SUPERFAMILY SSF46785 2 73 1.36E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06060 202dc61e64a4a9243609b29eaad2be68 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 4.7E-6 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS06060 202dc61e64a4a9243609b29eaad2be68 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 4.7E-6 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS06060 202dc61e64a4a9243609b29eaad2be68 237 Pfam PF07702 UTRA domain 93 229 1.3E-32 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 K08M4_RS06060 202dc61e64a4a9243609b29eaad2be68 237 SMART SM00345 10 69 2.7E-14 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS06060 202dc61e64a4a9243609b29eaad2be68 237 SMART SM00866 92 229 1.5E-29 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 K08M4_RS06060 202dc61e64a4a9243609b29eaad2be68 237 TIGRFAM TIGR02018 his_ut_repres: histidine utilization repressor 5 234 1.2E-90 T 05-07-2017 IPR010248 Histidine utilization repressor GO:0003677|GO:0006547|GO:0045892 K08M4_RS10370 f6de2589945bd0fd7584be5f09f42ad1 621 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 299 320 - T 05-07-2017 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-936440 K08M4_RS10370 f6de2589945bd0fd7584be5f09f42ad1 621 Pfam PF13616 PPIC-type PPIASE domain 262 362 1.5E-25 T 05-07-2017 K08M4_RS10370 f6de2589945bd0fd7584be5f09f42ad1 621 SUPERFAMILY SSF109998 203 244 1.57E-35 T 05-07-2017 IPR027304 Trigger factor/SurA domain K08M4_RS10370 f6de2589945bd0fd7584be5f09f42ad1 621 SUPERFAMILY SSF109998 39 169 1.57E-35 T 05-07-2017 IPR027304 Trigger factor/SurA domain K08M4_RS10370 f6de2589945bd0fd7584be5f09f42ad1 621 Gene3D G3DSA:3.10.50.40 262 385 1.0E-39 T 05-07-2017 K08M4_RS10370 f6de2589945bd0fd7584be5f09f42ad1 621 Pfam PF13624 SurA N-terminal domain 1 165 1.1E-49 T 05-07-2017 K08M4_RS10370 f6de2589945bd0fd7584be5f09f42ad1 621 SUPERFAMILY SSF54534 225 361 3.79E-29 T 05-07-2017 K08M4_RS01440 98ebac326f72b1b849c5051d0c880d04 124 PIRSF PIRSF002133 1 124 7.3E-54 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01440 98ebac326f72b1b849c5051d0c880d04 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 5.6E-70 T 05-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01440 98ebac326f72b1b849c5051d0c880d04 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.288 T 05-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01440 98ebac326f72b1b849c5051d0c880d04 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01440 98ebac326f72b1b849c5051d0c880d04 124 Gene3D G3DSA:2.40.50.140 1 123 1.3E-64 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS01440 98ebac326f72b1b849c5051d0c880d04 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 1.5E-42 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01440 98ebac326f72b1b849c5051d0c880d04 124 SUPERFAMILY SSF50249 3 123 8.05E-52 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS01440 98ebac326f72b1b849c5051d0c880d04 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 3.7E-60 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01440 98ebac326f72b1b849c5051d0c880d04 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 3.7E-60 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01440 98ebac326f72b1b849c5051d0c880d04 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 3.7E-60 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01440 98ebac326f72b1b849c5051d0c880d04 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 3.7E-60 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01440 98ebac326f72b1b849c5051d0c880d04 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 3.7E-60 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01440 98ebac326f72b1b849c5051d0c880d04 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 3.7E-60 T 05-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 2.0E-26 T 05-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 474 490 2.0E-26 T 05-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 190 202 2.0E-26 T 05-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 518 532 2.0E-26 T 05-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 Pfam PF02938 GAD domain 307 406 2.5E-29 T 05-07-2017 IPR029351 GAD domain Reactome: R-HSA-379726 K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 1 563 36.38 T 05-07-2017 K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 Gene3D G3DSA:2.40.50.140 1 106 6.1E-38 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 582 8.3E-261 T 05-07-2017 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 Gene3D G3DSA:3.30.930.10 415 584 1.7E-107 T 05-07-2017 K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 Gene3D G3DSA:3.30.930.10 131 275 1.7E-107 T 05-07-2017 K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 SUPERFAMILY SSF55261 288 419 4.41E-46 T 05-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 Pfam PF01336 OB-fold nucleic acid binding domain 18 102 3.0E-15 T 05-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 SUPERFAMILY SSF50249 1 105 4.19E-33 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 SUPERFAMILY SSF55681 108 287 2.49E-98 T 05-07-2017 K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 SUPERFAMILY SSF55681 420 582 2.49E-98 T 05-07-2017 K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 Pfam PF00152 tRNA synthetases class II (D, K and N) 117 558 1.2E-103 T 05-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS05515 689c640242ac6824c0652171aa6f0dc2 592 Gene3D G3DSA:3.30.1360.30 276 414 1.2E-45 T 05-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 SUPERFAMILY SSF47226 900 983 1.7E-18 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 SUPERFAMILY SSF52172 711 864 6.55E-30 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 PIRSF PIRSF036437 1 1006 0.0 T 05-07-2017 IPR014302 Signal transduction histidine kinase, TMAO sensor TorS GO:0000155|GO:0000160|GO:0004673|GO:0016021 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 Pfam PF00072 Response regulator receiver domain 713 831 2.1E-17 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 PRINTS PR00344 Bacterial sensor protein C-terminal signature 654 672 1.9E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 PRINTS PR00344 Bacterial sensor protein C-terminal signature 638 648 1.9E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 PRINTS PR00344 Bacterial sensor protein C-terminal signature 678 691 1.9E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 PRINTS PR00344 Bacterial sensor protein C-terminal signature 620 634 1.9E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 Pfam PF00512 His Kinase A (phospho-acceptor) domain 469 534 7.0E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 Gene3D G3DSA:3.40.50.2300 711 839 2.8E-29 T 05-07-2017 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 SUPERFAMILY SSF47384 457 535 2.55E-19 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 581 692 1.1E-27 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 TIGRFAM TIGR02956 TMAO_torS: TMAO reductase sytem sensor TorS 7 1004 0.0 T 05-07-2017 IPR014302 Signal transduction histidine kinase, TMAO sensor TorS GO:0000155|GO:0000160|GO:0004673|GO:0016021 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 Pfam PF00672 HAMP domain 340 408 4.2E-7 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 Pfam PF01627 Hpt domain 923 981 4.1E-11 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 Gene3D G3DSA:1.10.287.130 462 530 7.9E-15 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 SMART SM00387 581 694 8.9E-34 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 Gene3D G3DSA:3.30.565.10 542 692 2.9E-44 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 SUPERFAMILY SSF55874 523 696 1.06E-44 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 SMART SM00448 711 831 7.5E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 SMART SM00388 469 534 3.6E-22 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 SMART SM00073 911 1005 0.0014 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS19595 12d511e8c258d8f466cef662b86b6a22 1010 Gene3D G3DSA:1.20.120.160 914 1003 1.2E-22 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS01160 d7e3e99f682a756a90dc8f0230e5c0f2 429 PIRSF PIRSF000106 58 429 1.3E-72 T 05-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 K08M4_RS01160 d7e3e99f682a756a90dc8f0230e5c0f2 429 Gene3D G3DSA:3.40.50.10380 22 175 1.5E-48 T 05-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 K08M4_RS01160 d7e3e99f682a756a90dc8f0230e5c0f2 429 SUPERFAMILY SSF53223 25 176 9.35E-52 T 05-07-2017 K08M4_RS01160 d7e3e99f682a756a90dc8f0230e5c0f2 429 Pfam PF00390 Malic enzyme, N-terminal domain 35 129 2.1E-20 T 05-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 K08M4_RS01160 d7e3e99f682a756a90dc8f0230e5c0f2 429 Gene3D G3DSA:3.40.50.720 176 425 1.2E-86 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS01160 d7e3e99f682a756a90dc8f0230e5c0f2 429 SUPERFAMILY SSF51735 178 423 8.17E-81 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS01160 d7e3e99f682a756a90dc8f0230e5c0f2 429 SMART SM00919 178 414 4.5E-139 T 05-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 K08M4_RS01160 d7e3e99f682a756a90dc8f0230e5c0f2 429 ProSitePatterns PS00331 Malic enzymes signature. 174 190 - T 05-07-2017 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 K08M4_RS01160 d7e3e99f682a756a90dc8f0230e5c0f2 429 SMART SM01274 33 166 1.7E-74 T 05-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 K08M4_RS01160 d7e3e99f682a756a90dc8f0230e5c0f2 429 Pfam PF03949 Malic enzyme, NAD binding domain 180 374 4.3E-25 T 05-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 K08M4_RS06335 51f9e676c30d55ccf31b30b4c6607d4f 303 Pfam PF12688 Tetratrico peptide repeat 181 299 1.6E-11 T 05-07-2017 K08M4_RS06335 51f9e676c30d55ccf31b30b4c6607d4f 303 SUPERFAMILY SSF48452 146 268 4.14E-15 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS06335 51f9e676c30d55ccf31b30b4c6607d4f 303 SUPERFAMILY SSF55729 1 133 2.62E-19 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS06335 51f9e676c30d55ccf31b30b4c6607d4f 303 Gene3D G3DSA:3.40.630.30 32 131 8.9E-17 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS06335 51f9e676c30d55ccf31b30b4c6607d4f 303 Gene3D G3DSA:1.25.40.10 146 296 1.6E-16 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS06335 51f9e676c30d55ccf31b30b4c6607d4f 303 SMART SM00028 215 248 0.051 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS06335 51f9e676c30d55ccf31b30b4c6607d4f 303 SMART SM00028 178 211 110.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS06335 51f9e676c30d55ccf31b30b4c6607d4f 303 Pfam PF13673 Acetyltransferase (GNAT) domain 50 130 9.3E-9 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 Gene3D G3DSA:3.20.70.20 610 701 2.1E-43 T 05-07-2017 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 Gene3D G3DSA:3.20.70.20 129 344 2.1E-43 T 05-07-2017 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 Gene3D G3DSA:3.20.70.20 398 559 2.1E-43 T 05-07-2017 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 SUPERFAMILY SSF48168 10 221 1.31E-72 T 05-07-2017 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 142 219 2.4E-11 T 05-07-2017 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 Pfam PF03477 ATP cone domain 6 92 1.5E-18 T 05-07-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 SUPERFAMILY SSF51998 222 738 1.92E-165 T 05-07-2017 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 599 621 - T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 610 637 1.1E-40 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 433 444 1.1E-40 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 298 317 1.1E-40 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 473 496 1.1E-40 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 539 562 1.1E-40 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 511 533 1.1E-40 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 Pfam PF02867 Ribonucleotide reductase, barrel domain 223 731 2.9E-121 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS09100 ebc17576a170ae9ac48651715c038abe 760 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 145 735 2.8E-175 T 05-07-2017 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS11440 f566503fe486707b344a24f7f54efd5b 157 Gene3D G3DSA:3.10.50.30 78 156 1.3E-9 T 05-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 K08M4_RS11440 f566503fe486707b344a24f7f54efd5b 157 SUPERFAMILY SSF54534 78 156 1.23E-9 T 05-07-2017 K08M4_RS11440 f566503fe486707b344a24f7f54efd5b 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 81 156 5.2E-7 T 05-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 K08M4_RS11895 40f451719a8213714f670fd842113490 125 SUPERFAMILY SSF82649 1 125 1.2E-47 T 05-07-2017 K08M4_RS11895 40f451719a8213714f670fd842113490 125 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 124 2.3E-69 T 05-07-2017 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 K08M4_RS11895 40f451719a8213714f670fd842113490 125 Gene3D G3DSA:3.90.1010.10 2 124 5.1E-56 T 05-07-2017 K08M4_RS11895 40f451719a8213714f670fd842113490 125 Pfam PF01592 NifU-like N terminal domain 2 124 2.5E-56 T 05-07-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.6E-14 T 05-07-2017 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 1.6E-14 T 05-07-2017 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.6E-14 T 05-07-2017 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.6E-14 T 05-07-2017 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.6E-14 T 05-07-2017 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 Gene3D G3DSA:3.50.50.60 106 309 3.5E-47 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 679 695 - T 05-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 286 2.3E-53 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 800 0.0 T 05-07-2017 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 SUPERFAMILY SSF51905 144 310 4.53E-26 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 PIRSF PIRSF037149 1 836 0.0 T 05-07-2017 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 633 771 3.3E-14 T 05-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 Gene3D G3DSA:3.30.413.10 634 769 2.2E-30 T 05-07-2017 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 105 114 1.4E-9 T 05-07-2017 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 1.4E-9 T 05-07-2017 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 1.4E-9 T 05-07-2017 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 1.4E-9 T 05-07-2017 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 SUPERFAMILY SSF51905 2 184 5.19E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 SUPERFAMILY SSF55124 502 628 9.65E-30 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 560 622 1.1E-11 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 PRINTS PR00397 Sirohaem Fe-binding site signature 636 654 7.3E-6 T 05-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 PRINTS PR00397 Sirohaem Fe-binding site signature 679 697 7.3E-6 T 05-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 Pfam PF04324 BFD-like [2Fe-2S] binding domain 423 471 2.3E-14 T 05-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 SUPERFAMILY SSF56014 633 808 1.22E-45 T 05-07-2017 K08M4_RS18025 8a583b33f8fff02651fe7dbd81aacea6 852 Gene3D G3DSA:3.50.50.60 2 105 6.2E-25 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS20825 216a6db8b74ce3813b09eb11dbcda6d7 118 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 98 6.2E-17 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 K08M4_RS20825 216a6db8b74ce3813b09eb11dbcda6d7 118 Gene3D G3DSA:3.30.160.100 1 93 7.8E-22 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 K08M4_RS20825 216a6db8b74ce3813b09eb11dbcda6d7 118 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 92 4.6E-14 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 K08M4_RS20825 216a6db8b74ce3813b09eb11dbcda6d7 118 SUPERFAMILY SSF69754 2 101 4.05E-24 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 K08M4_RS17680 8d6c013a3d6465689254dff11741823a 206 SUPERFAMILY SSF47616 72 198 2.23E-16 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS17680 8d6c013a3d6465689254dff11741823a 206 Pfam PF00043 Glutathione S-transferase, C-terminal domain 129 191 6.1E-7 T 05-07-2017 IPR004046 Glutathione S-transferase, C-terminal K08M4_RS17680 8d6c013a3d6465689254dff11741823a 206 SUPERFAMILY SSF52833 1 78 5.08E-22 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS17680 8d6c013a3d6465689254dff11741823a 206 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 73 1.1E-17 T 05-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 K08M4_RS17680 8d6c013a3d6465689254dff11741823a 206 Gene3D G3DSA:3.40.30.10 2 86 1.6E-22 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS17680 8d6c013a3d6465689254dff11741823a 206 Gene3D G3DSA:1.20.1050.10 89 197 1.7E-11 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS16060 c05d7c0e1f965343ecb5d74749228b1d 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 286 3.3E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS16060 c05d7c0e1f965343ecb5d74749228b1d 296 SUPERFAMILY SSF161098 10 296 1.16E-68 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS16060 c05d7c0e1f965343ecb5d74749228b1d 296 Gene3D G3DSA:1.10.3720.10 7 283 5.5E-65 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS03950 874e05473930521ec0a30b43269997cb 462 Gene3D G3DSA:3.40.50.980 17 153 6.5E-9 T 05-07-2017 K08M4_RS03950 874e05473930521ec0a30b43269997cb 462 Pfam PF13193 AMP-binding enzyme C-terminal domain 367 450 5.2E-7 T 05-07-2017 IPR025110 AMP-binding enzyme C-terminal domain K08M4_RS03950 874e05473930521ec0a30b43269997cb 462 SUPERFAMILY SSF56801 23 460 4.32E-49 T 05-07-2017 K08M4_RS03950 874e05473930521ec0a30b43269997cb 462 Pfam PF00501 AMP-binding enzyme 18 296 4.8E-16 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 K08M4_RS03950 874e05473930521ec0a30b43269997cb 462 Gene3D G3DSA:3.30.300.30 356 460 4.0E-15 T 05-07-2017 K08M4_RS03950 874e05473930521ec0a30b43269997cb 462 Gene3D G3DSA:3.40.50.980 154 296 1.4E-13 T 05-07-2017 K08M4_RS20400 f9a0fc2ff1f8bf618ed3279a2799cebf 229 Pfam PF00072 Response regulator receiver domain 6 114 6.9E-23 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS20400 f9a0fc2ff1f8bf618ed3279a2799cebf 229 SMART SM00862 151 227 6.6E-16 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS20400 f9a0fc2ff1f8bf618ed3279a2799cebf 229 SUPERFAMILY SSF52172 2 125 3.27E-35 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS20400 f9a0fc2ff1f8bf618ed3279a2799cebf 229 SMART SM00448 4 114 2.5E-34 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS20400 f9a0fc2ff1f8bf618ed3279a2799cebf 229 Gene3D G3DSA:3.40.50.2300 2 124 6.2E-35 T 05-07-2017 K08M4_RS20400 f9a0fc2ff1f8bf618ed3279a2799cebf 229 SUPERFAMILY SSF46894 129 228 5.39E-22 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS20400 f9a0fc2ff1f8bf618ed3279a2799cebf 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 2.7E-17 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS20400 f9a0fc2ff1f8bf618ed3279a2799cebf 229 Gene3D G3DSA:1.10.10.10 130 228 8.1E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS11925 666c9f7afb1354d945eb7650f0833b26 618 Pfam PF13721 SecD export protein N-terminal TM region 2 103 4.5E-38 T 05-07-2017 IPR027398 SecD export protein N-terminal TM domain K08M4_RS11925 666c9f7afb1354d945eb7650f0833b26 618 Pfam PF02355 Protein export membrane protein 436 598 6.4E-19 T 05-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial K08M4_RS11925 666c9f7afb1354d945eb7650f0833b26 618 SUPERFAMILY SSF82866 413 609 3.14E-44 T 05-07-2017 K08M4_RS11925 666c9f7afb1354d945eb7650f0833b26 618 Pfam PF07549 SecD/SecF GG Motif 115 141 2.9E-7 T 05-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site K08M4_RS11925 666c9f7afb1354d945eb7650f0833b26 618 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 123 604 6.1E-149 T 05-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 K08M4_RS11925 666c9f7afb1354d945eb7650f0833b26 618 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 3 618 50.077 T 05-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 K08M4_RS11925 666c9f7afb1354d945eb7650f0833b26 618 PRINTS PR00702 Acriflavin resistance protein family signature 581 604 3.8E-5 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS11925 666c9f7afb1354d945eb7650f0833b26 618 PRINTS PR00702 Acriflavin resistance protein family signature 452 475 3.8E-5 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS11925 666c9f7afb1354d945eb7650f0833b26 618 PRINTS PR00702 Acriflavin resistance protein family signature 506 530 3.8E-5 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS11925 666c9f7afb1354d945eb7650f0833b26 618 Gene3D G3DSA:1.20.1640.10 434 612 2.2E-24 T 05-07-2017 K08M4_RS11925 666c9f7afb1354d945eb7650f0833b26 618 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 348 597 1.0E-80 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS21045 54a5b6faf2a00b5314d2d7055c1a3270 245 Gene3D G3DSA:3.90.79.10 89 204 2.9E-27 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS21045 54a5b6faf2a00b5314d2d7055c1a3270 245 Pfam PF00293 NUDIX domain 92 211 1.4E-20 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 K08M4_RS21045 54a5b6faf2a00b5314d2d7055c1a3270 245 SUPERFAMILY SSF55811 53 225 6.16E-28 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS21045 54a5b6faf2a00b5314d2d7055c1a3270 245 PRINTS PR00502 NUDIX hydrolase family signature 118 132 1.9E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 K08M4_RS21045 54a5b6faf2a00b5314d2d7055c1a3270 245 PRINTS PR00502 NUDIX hydrolase family signature 132 147 1.9E-6 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 K08M4_RS06110 991da2590cc2c0146220fce771238b55 183 SUPERFAMILY SSF55200 95 183 9.55E-34 T 05-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 K08M4_RS06110 991da2590cc2c0146220fce771238b55 183 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 11 183 29.584 T 05-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 K08M4_RS06110 991da2590cc2c0146220fce771238b55 183 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 19 88 1.7E-26 T 05-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 K08M4_RS06110 991da2590cc2c0146220fce771238b55 183 Gene3D G3DSA:3.10.20.80 13 90 5.9E-32 T 05-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 K08M4_RS06110 991da2590cc2c0146220fce771238b55 183 Gene3D G3DSA:3.30.110.10 91 183 3.9E-39 T 05-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 K08M4_RS06110 991da2590cc2c0146220fce771238b55 183 ProSitePatterns PS00938 Initiation factor 3 signature. 70 83 - T 05-07-2017 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 K08M4_RS06110 991da2590cc2c0146220fce771238b55 183 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 95 181 4.7E-36 T 05-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 K08M4_RS06110 991da2590cc2c0146220fce771238b55 183 SUPERFAMILY SSF54364 16 90 1.96E-25 T 05-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 K08M4_RS06110 991da2590cc2c0146220fce771238b55 183 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 19 183 1.8E-70 T 05-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 K08M4_RS13385 13b0ae567176d79476b9421dd6274f2d 73 TIGRFAM TIGR02975 phageshock_pspG: phage shock protein G 3 63 2.1E-21 T 05-07-2017 IPR014318 Phage shock protein, PspG K08M4_RS13385 13b0ae567176d79476b9421dd6274f2d 73 Pfam PF09583 Phage shock protein G (Phageshock_PspG) 1 64 6.9E-25 T 05-07-2017 IPR014318 Phage shock protein, PspG K08M4_RS11080 50b05e908f3fe04a79c97d61cc72c0c6 191 TIGRFAM TIGR00441 gmhA: phosphoheptose isomerase 35 187 9.4E-81 T 05-07-2017 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 K08M4_RS11080 50b05e908f3fe04a79c97d61cc72c0c6 191 SUPERFAMILY SSF53697 1 189 1.29E-50 T 05-07-2017 K08M4_RS11080 50b05e908f3fe04a79c97d61cc72c0c6 191 Gene3D G3DSA:3.40.50.10490 1 190 4.5E-63 T 05-07-2017 K08M4_RS11080 50b05e908f3fe04a79c97d61cc72c0c6 191 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 190 37.35 T 05-07-2017 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 K08M4_RS11080 50b05e908f3fe04a79c97d61cc72c0c6 191 Pfam PF13580 SIS domain 13 146 3.5E-30 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 SUPERFAMILY SSF47384 397 474 1.53E-21 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 SUPERFAMILY SSF52172 784 911 2.85E-34 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 Gene3D G3DSA:3.40.50.2300 951 1072 2.7E-40 T 05-07-2017 K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 Gene3D G3DSA:3.30.565.10 484 633 8.3E-46 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 Pfam PF00072 Response regulator receiver domain 955 1070 2.4E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 Pfam PF00072 Response regulator receiver domain 786 902 1.9E-22 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 522 635 6.0E-28 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 Gene3D G3DSA:3.40.50.2300 781 907 3.4E-39 T 05-07-2017 K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 SMART SM00388 409 474 3.1E-26 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 Gene3D G3DSA:1.10.287.130 405 470 4.5E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 SMART SM00448 784 902 5.3E-37 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 SMART SM00448 953 1070 2.5E-36 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 SMART SM00387 521 637 2.7E-37 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 SUPERFAMILY SSF52172 952 1072 6.97E-37 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 PRINTS PR00344 Bacterial sensor protein C-terminal signature 562 576 8.5E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 PRINTS PR00344 Bacterial sensor protein C-terminal signature 597 615 8.5E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 PRINTS PR00344 Bacterial sensor protein C-terminal signature 621 634 8.5E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 PRINTS PR00344 Bacterial sensor protein C-terminal signature 580 590 8.5E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 Pfam PF00512 His Kinase A (phospho-acceptor) domain 409 474 1.4E-20 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS19190 fe2b4f8cde58cba23fb0fe13d0ce18a5 1075 SUPERFAMILY SSF55874 463 634 7.07E-44 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS17925 cab35ead4bf06736c745903cb0feb750 334 Gene3D G3DSA:3.40.640.10 2 244 1.4E-88 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS17925 cab35ead4bf06736c745903cb0feb750 334 SUPERFAMILY SSF53383 1 332 2.82E-113 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS17925 cab35ead4bf06736c745903cb0feb750 334 Pfam PF01212 Beta-eliminating lyase 2 283 1.2E-96 T 05-07-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 K08M4_RS17925 cab35ead4bf06736c745903cb0feb750 334 Gene3D G3DSA:3.90.1150.10 245 334 2.9E-25 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS17925 cab35ead4bf06736c745903cb0feb750 334 PIRSF PIRSF017617 1 334 5.4E-131 T 05-07-2017 IPR023603 Threonine aldolase K08M4_RS02975 8cb5b3ff67e32dbffffd6d0a958c1367 573 SUPERFAMILY SSF81296 2 90 2.24E-14 T 05-07-2017 IPR014756 Immunoglobulin E-set K08M4_RS02975 8cb5b3ff67e32dbffffd6d0a958c1367 573 Pfam PF00759 Glycosyl hydrolase family 9 100 501 6.6E-25 T 05-07-2017 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 K08M4_RS02975 8cb5b3ff67e32dbffffd6d0a958c1367 573 SUPERFAMILY SSF48208 77 566 2.86E-94 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 K08M4_RS02975 8cb5b3ff67e32dbffffd6d0a958c1367 573 Gene3D G3DSA:1.50.10.10 99 562 5.8E-67 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 K08M4_RS02975 8cb5b3ff67e32dbffffd6d0a958c1367 573 Gene3D G3DSA:2.60.40.10 5 91 4.2E-13 T 05-07-2017 IPR013783 Immunoglobulin-like fold K08M4_RS02975 8cb5b3ff67e32dbffffd6d0a958c1367 573 Pfam PF02927 Cellulase N-terminal ig-like domain 5 83 4.1E-10 T 05-07-2017 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 K08M4_RS15165 129262c08a27bd3c8d091e15f617afd1 636 Pfam PF16448 LapD/MoxY periplasmic domain 23 146 5.0E-38 T 05-07-2017 IPR032244 LapD/MoxY, periplasmic domain K08M4_RS15165 129262c08a27bd3c8d091e15f617afd1 636 Gene3D G3DSA:3.30.70.270 239 387 2.7E-17 T 05-07-2017 K08M4_RS15165 129262c08a27bd3c8d091e15f617afd1 636 Gene3D G3DSA:3.20.20.450 410 635 2.7E-33 T 05-07-2017 IPR001633 EAL domain K08M4_RS15165 129262c08a27bd3c8d091e15f617afd1 636 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 234 386 1.4E-10 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS15165 129262c08a27bd3c8d091e15f617afd1 636 Pfam PF00563 EAL domain 412 634 1.7E-34 T 05-07-2017 IPR001633 EAL domain K08M4_RS15165 129262c08a27bd3c8d091e15f617afd1 636 SMART SM00052 403 635 1.6E-10 T 05-07-2017 IPR001633 EAL domain K08M4_RS15165 129262c08a27bd3c8d091e15f617afd1 636 SUPERFAMILY SSF141868 412 635 8.5E-38 T 05-07-2017 IPR001633 EAL domain K08M4_RS15165 129262c08a27bd3c8d091e15f617afd1 636 SMART SM00267 226 390 2.3E-13 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS15165 129262c08a27bd3c8d091e15f617afd1 636 Pfam PF00990 Diguanylate cyclase, GGDEF domain 237 386 1.1E-15 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS15165 129262c08a27bd3c8d091e15f617afd1 636 SUPERFAMILY SSF55073 243 385 1.8E-16 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS01595 d85717f198b834159b98b57816768577 126 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 5.0E-49 T 05-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01595 d85717f198b834159b98b57816768577 126 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 05-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01595 d85717f198b834159b98b57816768577 126 SUPERFAMILY SSF64263 1 119 5.76E-51 T 05-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01595 d85717f198b834159b98b57816768577 126 Pfam PF01196 Ribosomal protein L17 20 116 1.1E-34 T 05-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01595 d85717f198b834159b98b57816768577 126 Gene3D G3DSA:3.90.1030.10 1 117 1.7E-51 T 05-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01595 d85717f198b834159b98b57816768577 126 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.694 T 05-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 8 305 2.4E-115 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 7 307 38.596 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 303 2.0E-32 T 05-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 4.9E-26 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 4.9E-26 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 4.9E-26 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 4.9E-26 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 Gene3D G3DSA:3.40.50.1370 145 292 1.6E-55 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 SUPERFAMILY SSF53671 4 307 5.24E-102 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 Gene3D G3DSA:3.40.50.1370 7 144 1.2E-49 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 226 235 1.0E-36 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 79 88 1.0E-36 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 1.0E-36 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 1.0E-36 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 1.0E-36 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 1.0E-36 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS01895 0f923766eda65216ecab78880db44ece 309 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 4.9E-42 T 05-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 K08M4_RS20055 eb4b8c22dabd167fa9897f263488240e 147 Pfam PF12961 Domain of Unknown Function with PDB structure (DUF3850) 4 78 2.8E-21 T 05-07-2017 K08M4_RS20055 eb4b8c22dabd167fa9897f263488240e 147 SUPERFAMILY SSF88697 1 61 2.82E-7 T 05-07-2017 IPR015947 PUA-like domain K08M4_RS20055 eb4b8c22dabd167fa9897f263488240e 147 Gene3D G3DSA:3.10.480.10 2 37 9.2E-6 T 05-07-2017 K08M4_RS09485 e898c2a9a7543401d152f9a99bd24d70 362 Gene3D G3DSA:3.30.230.40 174 260 2.2E-38 T 05-07-2017 K08M4_RS09485 e898c2a9a7543401d152f9a99bd24d70 362 SUPERFAMILY SSF56784 3 151 1.09E-38 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS09485 e898c2a9a7543401d152f9a99bd24d70 362 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 233 246 - T 05-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 K08M4_RS09485 e898c2a9a7543401d152f9a99bd24d70 362 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 326 338 - T 05-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 K08M4_RS09485 e898c2a9a7543401d152f9a99bd24d70 362 Pfam PF08645 Polynucleotide kinase 3 phosphatase 6 132 3.7E-6 T 05-07-2017 IPR013954 Polynucleotide kinase 3 phosphatase Reactome: R-HSA-5649702 K08M4_RS09485 e898c2a9a7543401d152f9a99bd24d70 362 Gene3D G3DSA:3.30.230.40 264 362 8.5E-32 T 05-07-2017 K08M4_RS09485 e898c2a9a7543401d152f9a99bd24d70 362 TIGRFAM TIGR01261 hisB_Nterm: histidinol-phosphatase 5 169 2.5E-75 T 05-07-2017 IPR005954 Histidinol-phosphatase GO:0000105|GO:0004401|GO:0004424|GO:0005737 KEGG: 00340+4.2.1.19+3.1.3.15 K08M4_RS09485 e898c2a9a7543401d152f9a99bd24d70 362 SUPERFAMILY SSF54211 174 258 1.1E-32 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS09485 e898c2a9a7543401d152f9a99bd24d70 362 Gene3D G3DSA:3.40.50.1000 3 161 7.3E-43 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS09485 e898c2a9a7543401d152f9a99bd24d70 362 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 6 147 7.0E-48 T 05-07-2017 IPR006543 Histidinol-phosphate phosphatase GO:0016791 K08M4_RS09485 e898c2a9a7543401d152f9a99bd24d70 362 Hamap MF_01022 Histidine biosynthesis bifunctional protein HisB [hisB]. 4 362 54.555 T 05-07-2017 IPR020566 Histidine biosynthesis bifunctional protein HisB GO:0000105|GO:0004401|GO:0004424 KEGG: 00340+4.2.1.19+3.1.3.15 K08M4_RS09485 e898c2a9a7543401d152f9a99bd24d70 362 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 6 150 3.6E-28 T 05-07-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 K08M4_RS09485 e898c2a9a7543401d152f9a99bd24d70 362 SUPERFAMILY SSF54211 259 349 4.17E-31 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS09485 e898c2a9a7543401d152f9a99bd24d70 362 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 203 344 5.1E-66 T 05-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 K08M4_RS09485 e898c2a9a7543401d152f9a99bd24d70 362 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 174 362 38.108 T 05-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 K08M4_RS13860 f15f93c28406826349f94914ac53696c 395 Pfam PF00534 Glycosyl transferases group 1 202 292 6.1E-10 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 K08M4_RS13860 f15f93c28406826349f94914ac53696c 395 SUPERFAMILY SSF53756 3 319 2.07E-26 T 05-07-2017 K08M4_RS03205 b38847bb5698d5fee557de0e4e05ce4e 276 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 9.1E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS03205 b38847bb5698d5fee557de0e4e05ce4e 276 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 9.1E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS03205 b38847bb5698d5fee557de0e4e05ce4e 276 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 9.1E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS03205 b38847bb5698d5fee557de0e4e05ce4e 276 Gene3D G3DSA:1.10.10.10 2 82 1.2E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS03205 b38847bb5698d5fee557de0e4e05ce4e 276 SUPERFAMILY SSF46785 2 82 3.54E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS03205 b38847bb5698d5fee557de0e4e05ce4e 276 SUPERFAMILY SSF53850 101 273 5.07E-18 T 05-07-2017 K08M4_RS03205 b38847bb5698d5fee557de0e4e05ce4e 276 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 60 2.1E-15 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS03205 b38847bb5698d5fee557de0e4e05ce4e 276 Gene3D G3DSA:3.40.190.10 160 244 3.0E-13 T 05-07-2017 K08M4_RS03205 b38847bb5698d5fee557de0e4e05ce4e 276 Pfam PF03466 LysR substrate binding domain 114 273 8.8E-10 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS03520 4c1ff29a1712e73da6df2d39c33b15ce 324 Gene3D G3DSA:3.30.1330.10 3 139 9.8E-42 T 05-07-2017 IPR016188 PurM-like, N-terminal domain K08M4_RS03520 4c1ff29a1712e73da6df2d39c33b15ce 324 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 2 318 28.748 T 05-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 K08M4_RS03520 4c1ff29a1712e73da6df2d39c33b15ce 324 SUPERFAMILY SSF55326 3 137 4.45E-33 T 05-07-2017 K08M4_RS03520 4c1ff29a1712e73da6df2d39c33b15ce 324 SUPERFAMILY SSF56042 142 298 3.89E-33 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain K08M4_RS03520 4c1ff29a1712e73da6df2d39c33b15ce 324 Gene3D G3DSA:3.90.650.10 144 321 6.1E-47 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain K08M4_RS03520 4c1ff29a1712e73da6df2d39c33b15ce 324 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 3 321 1.6E-102 T 05-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 K08M4_RS03520 4c1ff29a1712e73da6df2d39c33b15ce 324 Pfam PF02769 AIR synthase related protein, C-terminal domain 149 298 6.4E-9 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain K08M4_RS03520 4c1ff29a1712e73da6df2d39c33b15ce 324 PIRSF PIRSF005303 1 321 2.5E-81 T 05-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 K08M4_RS03520 4c1ff29a1712e73da6df2d39c33b15ce 324 Pfam PF00586 AIR synthase related protein, N-terminal domain 28 137 1.7E-20 T 05-07-2017 IPR016188 PurM-like, N-terminal domain K08M4_RS19750 10d9a6b7343816cd5114073ec98fa2aa 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.1E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19750 10d9a6b7343816cd5114073ec98fa2aa 300 SUPERFAMILY SSF53850 87 290 8.07E-23 T 05-07-2017 K08M4_RS19750 10d9a6b7343816cd5114073ec98fa2aa 300 Gene3D G3DSA:3.40.190.10 188 253 3.2E-6 T 05-07-2017 K08M4_RS19750 10d9a6b7343816cd5114073ec98fa2aa 300 Gene3D G3DSA:1.10.10.10 2 81 3.8E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19750 10d9a6b7343816cd5114073ec98fa2aa 300 Pfam PF03466 LysR substrate binding domain 88 274 6.5E-17 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS19750 10d9a6b7343816cd5114073ec98fa2aa 300 Gene3D G3DSA:3.40.190.10 93 187 2.9E-8 T 05-07-2017 K08M4_RS19750 10d9a6b7343816cd5114073ec98fa2aa 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.4E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19750 10d9a6b7343816cd5114073ec98fa2aa 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.4E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19750 10d9a6b7343816cd5114073ec98fa2aa 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.4E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19750 10d9a6b7343816cd5114073ec98fa2aa 300 SUPERFAMILY SSF46785 3 85 1.25E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS18510 b8a0a64b599fe642a21dba88497f2e53 490 SUPERFAMILY SSF55874 360 486 5.63E-17 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS18510 b8a0a64b599fe642a21dba88497f2e53 490 SMART SM00387 387 485 4.8E-13 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS18510 b8a0a64b599fe642a21dba88497f2e53 490 SMART SM00388 282 349 5.0E-5 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS18510 b8a0a64b599fe642a21dba88497f2e53 490 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 392 483 2.1E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS18510 b8a0a64b599fe642a21dba88497f2e53 490 SUPERFAMILY SSF47384 277 348 5.49E-7 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS18510 b8a0a64b599fe642a21dba88497f2e53 490 Pfam PF00512 His Kinase A (phospho-acceptor) domain 287 338 2.6E-6 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS18510 b8a0a64b599fe642a21dba88497f2e53 490 Gene3D G3DSA:3.30.565.10 373 485 1.2E-15 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS18510 b8a0a64b599fe642a21dba88497f2e53 490 Pfam PF11884 Domain of unknown function (DUF3404) 23 281 1.1E-111 T 05-07-2017 IPR021821 Protein of unknown function DUF3404 K08M4_RS18510 b8a0a64b599fe642a21dba88497f2e53 490 Gene3D G3DSA:1.10.287.130 277 327 9.5E-5 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 312 330 2.0E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 348 2.0E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 283 297 2.0E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 Gene3D G3DSA:1.10.287.130 125 187 6.5E-12 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 235 348 3.9E-18 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 SUPERFAMILY SSF55785 5 103 3.49E-9 T 05-07-2017 IPR000014 PAS domain K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 SMART SM00387 234 349 2.3E-29 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 Gene3D G3DSA:3.30.565.10 196 349 1.2E-36 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 Pfam PF00512 His Kinase A (phospho-acceptor) domain 134 191 5.8E-14 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 Pfam PF00989 PAS fold 9 110 5.8E-13 T 05-07-2017 IPR013767 PAS fold GO:0006355 K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 SMART SM00388 130 195 3.2E-12 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 SUPERFAMILY SSF55874 199 348 6.94E-36 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 SUPERFAMILY SSF47384 126 191 6.28E-12 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 9 122 9.3E-6 T 05-07-2017 IPR000014 PAS domain K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 SMART SM00091 5 73 6.5E-8 T 05-07-2017 IPR000014 PAS domain K08M4_RS14320 12ca9593c2e17369b0c2bd3bf5b1a9b4 349 Gene3D G3DSA:3.30.450.20 4 112 1.3E-27 T 05-07-2017 K08M4_RS19405 24963d761033dceb0a789d3a20f0ccbc 182 Gene3D G3DSA:3.10.290.10 21 94 9.6E-28 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS19405 24963d761033dceb0a789d3a20f0ccbc 182 SUPERFAMILY SSF55174 22 94 5.63E-17 T 05-07-2017 K08M4_RS19405 24963d761033dceb0a789d3a20f0ccbc 182 Pfam PF13275 S4 domain 31 93 1.0E-21 T 05-07-2017 K08M4_RS20380 eb903761c7b78c5b83f992a8c820afed 189 ProSitePatterns PS00194 Thioredoxin family active site. 88 106 - T 05-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 K08M4_RS20380 eb903761c7b78c5b83f992a8c820afed 189 SUPERFAMILY SSF52833 68 178 1.27E-24 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS20380 eb903761c7b78c5b83f992a8c820afed 189 Gene3D G3DSA:3.40.30.10 40 177 1.5E-23 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS20380 eb903761c7b78c5b83f992a8c820afed 189 Pfam PF08534 Redoxin 72 177 1.1E-13 T 05-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 K08M4_RS20365 85804242fe7dc8dd54810bae0d43d815 534 Pfam PF00924 Mechanosensitive ion channel 327 519 1.0E-53 T 05-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 K08M4_RS20365 85804242fe7dc8dd54810bae0d43d815 534 Gene3D G3DSA:3.30.70.100 434 517 8.7E-31 T 05-07-2017 K08M4_RS20365 85804242fe7dc8dd54810bae0d43d815 534 Gene3D G3DSA:2.30.30.60 380 428 3.7E-16 T 05-07-2017 K08M4_RS20365 85804242fe7dc8dd54810bae0d43d815 534 SUPERFAMILY SSF50182 364 430 4.9E-18 T 05-07-2017 IPR010920 LSM domain K08M4_RS20365 85804242fe7dc8dd54810bae0d43d815 534 SUPERFAMILY SSF82861 277 363 4.45E-14 T 05-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 K08M4_RS20365 85804242fe7dc8dd54810bae0d43d815 534 SUPERFAMILY SSF82689 433 530 2.88E-34 T 05-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 K08M4_RS00370 6e90891a0ae53d59f416951eeb9a40ff 162 Gene3D G3DSA:1.10.10.60 21 86 4.0E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00370 6e90891a0ae53d59f416951eeb9a40ff 162 Pfam PF13551 Winged helix-turn helix 24 83 6.4E-13 T 05-07-2017 K08M4_RS00370 6e90891a0ae53d59f416951eeb9a40ff 162 SUPERFAMILY SSF46689 16 132 1.43E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00370 6e90891a0ae53d59f416951eeb9a40ff 162 Pfam PF13592 Winged helix-turn helix 99 156 2.1E-13 T 05-07-2017 IPR025959 Winged helix-turn helix domain K08M4_RS00145 6e90891a0ae53d59f416951eeb9a40ff 162 Gene3D G3DSA:1.10.10.60 21 86 4.0E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00145 6e90891a0ae53d59f416951eeb9a40ff 162 Pfam PF13551 Winged helix-turn helix 24 83 6.4E-13 T 05-07-2017 K08M4_RS00145 6e90891a0ae53d59f416951eeb9a40ff 162 SUPERFAMILY SSF46689 16 132 1.43E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00145 6e90891a0ae53d59f416951eeb9a40ff 162 Pfam PF13592 Winged helix-turn helix 99 156 2.1E-13 T 05-07-2017 IPR025959 Winged helix-turn helix domain K08M4_RS20630 6e90891a0ae53d59f416951eeb9a40ff 162 Gene3D G3DSA:1.10.10.60 21 86 4.0E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20630 6e90891a0ae53d59f416951eeb9a40ff 162 Pfam PF13551 Winged helix-turn helix 24 83 6.4E-13 T 05-07-2017 K08M4_RS20630 6e90891a0ae53d59f416951eeb9a40ff 162 SUPERFAMILY SSF46689 16 132 1.43E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20630 6e90891a0ae53d59f416951eeb9a40ff 162 Pfam PF13592 Winged helix-turn helix 99 156 2.1E-13 T 05-07-2017 IPR025959 Winged helix-turn helix domain K08M4_RS12075 6e90891a0ae53d59f416951eeb9a40ff 162 Gene3D G3DSA:1.10.10.60 21 86 4.0E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS12075 6e90891a0ae53d59f416951eeb9a40ff 162 Pfam PF13551 Winged helix-turn helix 24 83 6.4E-13 T 05-07-2017 K08M4_RS12075 6e90891a0ae53d59f416951eeb9a40ff 162 SUPERFAMILY SSF46689 16 132 1.43E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS12075 6e90891a0ae53d59f416951eeb9a40ff 162 Pfam PF13592 Winged helix-turn helix 99 156 2.1E-13 T 05-07-2017 IPR025959 Winged helix-turn helix domain K08M4_RS00735 6e90891a0ae53d59f416951eeb9a40ff 162 Gene3D G3DSA:1.10.10.60 21 86 4.0E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00735 6e90891a0ae53d59f416951eeb9a40ff 162 Pfam PF13551 Winged helix-turn helix 24 83 6.4E-13 T 05-07-2017 K08M4_RS00735 6e90891a0ae53d59f416951eeb9a40ff 162 SUPERFAMILY SSF46689 16 132 1.43E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00735 6e90891a0ae53d59f416951eeb9a40ff 162 Pfam PF13592 Winged helix-turn helix 99 156 2.1E-13 T 05-07-2017 IPR025959 Winged helix-turn helix domain K08M4_RS00380 6e90891a0ae53d59f416951eeb9a40ff 162 Gene3D G3DSA:1.10.10.60 21 86 4.0E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00380 6e90891a0ae53d59f416951eeb9a40ff 162 Pfam PF13551 Winged helix-turn helix 24 83 6.4E-13 T 05-07-2017 K08M4_RS00380 6e90891a0ae53d59f416951eeb9a40ff 162 SUPERFAMILY SSF46689 16 132 1.43E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00380 6e90891a0ae53d59f416951eeb9a40ff 162 Pfam PF13592 Winged helix-turn helix 99 156 2.1E-13 T 05-07-2017 IPR025959 Winged helix-turn helix domain K08M4_RS11335 6e90891a0ae53d59f416951eeb9a40ff 162 Gene3D G3DSA:1.10.10.60 21 86 4.0E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS11335 6e90891a0ae53d59f416951eeb9a40ff 162 Pfam PF13551 Winged helix-turn helix 24 83 6.4E-13 T 05-07-2017 K08M4_RS11335 6e90891a0ae53d59f416951eeb9a40ff 162 SUPERFAMILY SSF46689 16 132 1.43E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS11335 6e90891a0ae53d59f416951eeb9a40ff 162 Pfam PF13592 Winged helix-turn helix 99 156 2.1E-13 T 05-07-2017 IPR025959 Winged helix-turn helix domain K08M4_RS11655 162dfbda9baf2c1b1364bf5fa68e9458 149 Pfam PF13633 Prokaryotic N-terminal methylation site 5 31 1.0E-7 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS11655 162dfbda9baf2c1b1364bf5fa68e9458 149 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 27 8.1E-4 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS11655 162dfbda9baf2c1b1364bf5fa68e9458 149 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS12470 95bcd29dc5d3382c51dc64524534a7ea 1487 Pfam PF01645 Conserved region in glutamate synthase 794 1157 3.7E-152 T 05-07-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 K08M4_RS12470 95bcd29dc5d3382c51dc64524534a7ea 1487 Gene3D G3DSA:2.160.20.60 1213 1465 3.7E-94 T 05-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 K08M4_RS12470 95bcd29dc5d3382c51dc64524534a7ea 1487 Gene3D G3DSA:3.20.20.70 441 782 1.2E-97 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS12470 95bcd29dc5d3382c51dc64524534a7ea 1487 Pfam PF01493 GXGXG motif 1236 1418 6.1E-72 T 05-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 K08M4_RS12470 95bcd29dc5d3382c51dc64524534a7ea 1487 Gene3D G3DSA:3.20.20.70 819 1191 1.3E-163 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS12470 95bcd29dc5d3382c51dc64524534a7ea 1487 SUPERFAMILY SSF69336 1213 1465 8.63E-87 T 05-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 K08M4_RS12470 95bcd29dc5d3382c51dc64524534a7ea 1487 SUPERFAMILY SSF51395 435 1191 5.7E-250 T 05-07-2017 K08M4_RS12470 95bcd29dc5d3382c51dc64524534a7ea 1487 Gene3D G3DSA:3.60.20.10 13 435 2.9E-171 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS12470 95bcd29dc5d3382c51dc64524534a7ea 1487 Pfam PF04898 Glutamate synthase central domain 458 738 2.5E-100 T 05-07-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 K08M4_RS12470 95bcd29dc5d3382c51dc64524534a7ea 1487 Pfam PF00310 Glutamine amidotransferases class-II 13 426 2.2E-177 T 05-07-2017 IPR017932 Glutamine amidotransferase type 2 domain K08M4_RS12470 95bcd29dc5d3382c51dc64524534a7ea 1487 SUPERFAMILY SSF56235 13 430 3.17E-148 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS12715 fdec665d0f3441d279ba7043491ea095 274 Pfam PF00149 Calcineurin-like phosphoesterase 15 206 2.3E-15 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 K08M4_RS12715 fdec665d0f3441d279ba7043491ea095 274 SUPERFAMILY SSF56300 13 259 1.5E-57 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS12715 fdec665d0f3441d279ba7043491ea095 274 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 14 260 40.479 T 05-07-2017 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 K08M4_RS12715 fdec665d0f3441d279ba7043491ea095 274 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 205 260 8.0E-19 T 05-07-2017 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 K08M4_RS12715 fdec665d0f3441d279ba7043491ea095 274 Gene3D G3DSA:3.60.21.10 12 255 1.6E-41 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS14950 c5332a4279b4f91d914e29ca6394d44d 293 Gene3D G3DSA:1.10.10.10 145 174 9.0E-4 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS14950 c5332a4279b4f91d914e29ca6394d44d 293 Pfam PF02195 ParB-like nuclease domain 47 130 7.7E-27 T 05-07-2017 IPR003115 ParB/Sulfiredoxin K08M4_RS14950 c5332a4279b4f91d914e29ca6394d44d 293 SUPERFAMILY SSF110849 41 132 4.45E-26 T 05-07-2017 IPR003115 ParB/Sulfiredoxin K08M4_RS14950 c5332a4279b4f91d914e29ca6394d44d 293 SMART SM00470 40 130 2.7E-32 T 05-07-2017 IPR003115 ParB/Sulfiredoxin K08M4_RS14950 c5332a4279b4f91d914e29ca6394d44d 293 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 37 213 2.5E-55 T 05-07-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 K08M4_RS14950 c5332a4279b4f91d914e29ca6394d44d 293 Gene3D G3DSA:3.90.1530.10 35 136 3.2E-38 T 05-07-2017 K08M4_RS14950 c5332a4279b4f91d914e29ca6394d44d 293 SUPERFAMILY SSF109709 122 230 5.75E-32 T 05-07-2017 K08M4_RS15180 f96ae066792e70b59ba3d558732a34d2 435 SUPERFAMILY SSF47384 196 277 6.28E-17 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS15180 f96ae066792e70b59ba3d558732a34d2 435 Pfam PF00512 His Kinase A (phospho-acceptor) domain 213 276 1.2E-13 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS15180 f96ae066792e70b59ba3d558732a34d2 435 SUPERFAMILY SSF158472 160 210 3.4E-6 T 05-07-2017 K08M4_RS15180 f96ae066792e70b59ba3d558732a34d2 435 SUPERFAMILY SSF55874 266 427 5.37E-32 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS15180 f96ae066792e70b59ba3d558732a34d2 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 408 2.4E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS15180 f96ae066792e70b59ba3d558732a34d2 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 383 2.4E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS15180 f96ae066792e70b59ba3d558732a34d2 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 428 2.4E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS15180 f96ae066792e70b59ba3d558732a34d2 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 2.4E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS15180 f96ae066792e70b59ba3d558732a34d2 435 Gene3D G3DSA:3.30.565.10 263 431 2.9E-35 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS15180 f96ae066792e70b59ba3d558732a34d2 435 Gene3D G3DSA:1.10.287.130 202 262 1.9E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS15180 f96ae066792e70b59ba3d558732a34d2 435 Pfam PF00672 HAMP domain 141 207 4.5E-9 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS15180 f96ae066792e70b59ba3d558732a34d2 435 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 429 1.6E-17 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS15180 f96ae066792e70b59ba3d558732a34d2 435 SMART SM00387 320 431 9.1E-29 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS15180 f96ae066792e70b59ba3d558732a34d2 435 SMART SM00388 212 277 3.1E-15 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS15180 f96ae066792e70b59ba3d558732a34d2 435 SMART SM00304 159 211 2.9E-10 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS10385 874679ff504386c77b8764e72f139e99 426 Pfam PF06689 ClpX C4-type zinc finger 14 51 3.0E-21 T 05-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 K08M4_RS10385 874679ff504386c77b8764e72f139e99 426 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 12 414 6.5E-209 T 05-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 K08M4_RS10385 874679ff504386c77b8764e72f139e99 426 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 417 53.224 T 05-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 K08M4_RS10385 874679ff504386c77b8764e72f139e99 426 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 319 396 1.1E-15 T 05-07-2017 IPR019489 Clp ATPase, C-terminal K08M4_RS10385 874679ff504386c77b8764e72f139e99 426 SUPERFAMILY SSF57716 14 49 5.84E-12 T 05-07-2017 K08M4_RS10385 874679ff504386c77b8764e72f139e99 426 Gene3D G3DSA:1.10.8.60 318 418 1.3E-37 T 05-07-2017 K08M4_RS10385 874679ff504386c77b8764e72f139e99 426 SUPERFAMILY SSF52540 63 404 1.21E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10385 874679ff504386c77b8764e72f139e99 426 SMART SM01086 319 414 2.2E-33 T 05-07-2017 IPR019489 Clp ATPase, C-terminal K08M4_RS10385 874679ff504386c77b8764e72f139e99 426 SMART SM00994 13 52 1.0E-24 T 05-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 K08M4_RS10385 874679ff504386c77b8764e72f139e99 426 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 312 6.5E-49 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 K08M4_RS10385 874679ff504386c77b8764e72f139e99 426 SMART SM00382 113 266 2.0E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS10385 874679ff504386c77b8764e72f139e99 426 Gene3D G3DSA:3.40.50.300 66 255 8.8E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10385 874679ff504386c77b8764e72f139e99 426 Gene3D G3DSA:3.40.50.300 296 312 8.8E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08950 199d7361c5d8888803a9f1fd4c0829fd 627 Gene3D G3DSA:1.10.287.950 380 597 6.8E-55 T 05-07-2017 K08M4_RS08950 199d7361c5d8888803a9f1fd4c0829fd 627 SMART SM00304 296 350 7.7E-11 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS08950 199d7361c5d8888803a9f1fd4c0829fd 627 SMART SM00304 353 403 21.0 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS08950 199d7361c5d8888803a9f1fd4c0829fd 627 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 430 625 1.7E-45 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS08950 199d7361c5d8888803a9f1fd4c0829fd 627 SMART SM00283 365 626 1.6E-64 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS08950 199d7361c5d8888803a9f1fd4c0829fd 627 Pfam PF02743 Cache domain 40 258 3.5E-31 T 05-07-2017 IPR033479 Double Cache domain 1 K08M4_RS08950 199d7361c5d8888803a9f1fd4c0829fd 627 SUPERFAMILY SSF58104 318 627 6.93E-77 T 05-07-2017 K08M4_RS08950 199d7361c5d8888803a9f1fd4c0829fd 627 Pfam PF00672 HAMP domain 278 346 2.2E-12 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS08950 199d7361c5d8888803a9f1fd4c0829fd 627 SUPERFAMILY SSF103190 90 174 1.1E-11 T 05-07-2017 IPR029151 Periplasmic sensor domain-like K08M4_RS08950 199d7361c5d8888803a9f1fd4c0829fd 627 Gene3D G3DSA:3.30.450.20 134 269 1.6E-29 T 05-07-2017 K08M4_RS04190 853fd887eb9221a1db29aca15409a3fc 347 Gene3D G3DSA:3.40.1550.10 60 230 5.8E-6 T 05-07-2017 IPR028976 CheC-like domain K08M4_RS04190 853fd887eb9221a1db29aca15409a3fc 347 PRINTS PR00955 Flagellar motor switch protein FliM signature 88 104 9.9E-19 T 05-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 K08M4_RS04190 853fd887eb9221a1db29aca15409a3fc 347 PRINTS PR00955 Flagellar motor switch protein FliM signature 2 15 9.9E-19 T 05-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 K08M4_RS04190 853fd887eb9221a1db29aca15409a3fc 347 PRINTS PR00955 Flagellar motor switch protein FliM signature 113 132 9.9E-19 T 05-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 K08M4_RS04190 853fd887eb9221a1db29aca15409a3fc 347 PRINTS PR00955 Flagellar motor switch protein FliM signature 211 229 9.9E-19 T 05-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 K08M4_RS04190 853fd887eb9221a1db29aca15409a3fc 347 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 3 320 1.4E-123 T 05-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 K08M4_RS04190 853fd887eb9221a1db29aca15409a3fc 347 Pfam PF02154 Flagellar motor switch protein FliM 37 229 2.1E-83 T 05-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 K08M4_RS04190 853fd887eb9221a1db29aca15409a3fc 347 Gene3D G3DSA:2.30.330.10 243 322 9.9E-11 T 05-07-2017 K08M4_RS04190 853fd887eb9221a1db29aca15409a3fc 347 SUPERFAMILY SSF101801 247 322 3.66E-14 T 05-07-2017 IPR001543 Surface presentation of antigen (SpoA) K08M4_RS04190 853fd887eb9221a1db29aca15409a3fc 347 SUPERFAMILY SSF103039 54 230 6.54E-21 T 05-07-2017 IPR028976 CheC-like domain K08M4_RS04190 853fd887eb9221a1db29aca15409a3fc 347 SUPERFAMILY SSF103039 4 13 6.54E-21 T 05-07-2017 IPR028976 CheC-like domain K08M4_RS04190 853fd887eb9221a1db29aca15409a3fc 347 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 250 319 3.6E-18 T 05-07-2017 IPR001543 Surface presentation of antigen (SpoA) K08M4_RS04190 853fd887eb9221a1db29aca15409a3fc 347 PIRSF PIRSF002888 1 328 7.2E-93 T 05-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 K08M4_RS06490 2c6a416f39746056b858206885ff32ae 295 TIGRFAM TIGR01355 cyt_deam_dimer: cytidine deaminase 29 294 4.3E-93 T 05-07-2017 IPR006263 Cytidine deaminase, homodimeric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 K08M4_RS06490 2c6a416f39746056b858206885ff32ae 295 Pfam PF08211 Cytidine and deoxycytidylate deaminase zinc-binding region 157 277 2.8E-39 T 05-07-2017 IPR013171 Cytidine/deoxycytidylate deaminase, zinc-binding domain GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 K08M4_RS06490 2c6a416f39746056b858206885ff32ae 295 PIRSF PIRSF006334 14 295 1.2E-101 T 05-07-2017 IPR006263 Cytidine deaminase, homodimeric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 K08M4_RS06490 2c6a416f39746056b858206885ff32ae 295 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 60 142 4.3E-12 T 05-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 K08M4_RS06490 2c6a416f39746056b858206885ff32ae 295 Gene3D G3DSA:3.40.140.10 183 290 9.3E-21 T 05-07-2017 K08M4_RS06490 2c6a416f39746056b858206885ff32ae 295 Hamap MF_01558 Cytidine deaminase [cdd]. 1 293 48.29 T 05-07-2017 IPR020797 Cytidine deaminase, bacteria GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 K08M4_RS06490 2c6a416f39746056b858206885ff32ae 295 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 102 136 - T 05-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 K08M4_RS06490 2c6a416f39746056b858206885ff32ae 295 SUPERFAMILY SSF53927 1 146 4.52E-39 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 K08M4_RS06490 2c6a416f39746056b858206885ff32ae 295 SUPERFAMILY SSF53927 152 292 2.6E-32 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 K08M4_RS06490 2c6a416f39746056b858206885ff32ae 295 Gene3D G3DSA:3.40.140.10 33 175 8.3E-43 T 05-07-2017 K08M4_RS09695 d4c05b75118478ce753cbe19b5759cc1 427 Gene3D G3DSA:3.90.1150.10 329 420 4.2E-58 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS09695 d4c05b75118478ce753cbe19b5759cc1 427 Gene3D G3DSA:3.90.1150.10 3 58 4.2E-58 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS09695 d4c05b75118478ce753cbe19b5759cc1 427 PIRSF PIRSF000521 21 421 9.6E-37 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 K08M4_RS09695 d4c05b75118478ce753cbe19b5759cc1 427 Pfam PF00202 Aminotransferase class-III 24 418 1.2E-129 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 K08M4_RS09695 d4c05b75118478ce753cbe19b5759cc1 427 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 1 421 49.262 T 05-07-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 K08M4_RS09695 d4c05b75118478ce753cbe19b5759cc1 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 K08M4_RS09695 d4c05b75118478ce753cbe19b5759cc1 427 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 10 418 3.2E-178 T 05-07-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 K08M4_RS09695 d4c05b75118478ce753cbe19b5759cc1 427 SUPERFAMILY SSF53383 4 420 1.1E-136 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS09695 d4c05b75118478ce753cbe19b5759cc1 427 Gene3D G3DSA:3.40.640.10 59 326 1.5E-90 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS09455 8f8f807fc672ec5d7133224a1b183472 405 PIRSF PIRSF003180 1 403 1.9E-156 T 05-07-2017 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing K08M4_RS09455 8f8f807fc672ec5d7133224a1b183472 405 Gene3D G3DSA:1.10.3150.10 182 398 4.4E-34 T 05-07-2017 IPR013976 Metal-dependent hydrolase HDOD K08M4_RS09455 8f8f807fc672ec5d7133224a1b183472 405 SUPERFAMILY SSF141868 5 193 9.94E-29 T 05-07-2017 IPR001633 EAL domain K08M4_RS09455 8f8f807fc672ec5d7133224a1b183472 405 Gene3D G3DSA:3.20.20.450 80 181 3.7E-12 T 05-07-2017 IPR001633 EAL domain K08M4_RS09455 8f8f807fc672ec5d7133224a1b183472 405 SMART SM00052 2 195 0.0017 T 05-07-2017 IPR001633 EAL domain K08M4_RS09455 8f8f807fc672ec5d7133224a1b183472 405 SUPERFAMILY SSF109604 181 399 1.32E-43 T 05-07-2017 K08M4_RS09455 8f8f807fc672ec5d7133224a1b183472 405 Pfam PF08668 HDOD domain 205 319 1.2E-12 T 05-07-2017 IPR013976 Metal-dependent hydrolase HDOD K08M4_RS09455 8f8f807fc672ec5d7133224a1b183472 405 Pfam PF00563 EAL domain 77 190 1.1E-14 T 05-07-2017 IPR001633 EAL domain K08M4_RS02755 ae74e32adf7ca932bf698491704bfb4c 184 Gene3D G3DSA:2.30.30.240 108 184 1.1E-29 T 05-07-2017 K08M4_RS02755 ae74e32adf7ca932bf698491704bfb4c 184 SUPERFAMILY SSF50447 15 102 4.24E-24 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain K08M4_RS02755 ae74e32adf7ca932bf698491704bfb4c 184 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 16 184 3.5E-56 T 05-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 K08M4_RS02755 ae74e32adf7ca932bf698491704bfb4c 184 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 15 184 23.822 T 05-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 K08M4_RS02755 ae74e32adf7ca932bf698491704bfb4c 184 SUPERFAMILY SSF50346 108 184 3.34E-20 T 05-07-2017 IPR011033 PRC-barrel-like K08M4_RS02755 ae74e32adf7ca932bf698491704bfb4c 184 Pfam PF01782 RimM N-terminal domain 18 97 9.7E-25 T 05-07-2017 IPR002676 RimM protein GO:0006364 K08M4_RS02755 ae74e32adf7ca932bf698491704bfb4c 184 Gene3D G3DSA:2.40.30.60 7 102 4.7E-33 T 05-07-2017 IPR002676 RimM protein GO:0006364 K08M4_RS02755 ae74e32adf7ca932bf698491704bfb4c 184 Pfam PF05239 PRC-barrel domain 105 179 4.0E-13 T 05-07-2017 IPR027275 PRC-barrel domain K08M4_RS12120 8bceb513732a67b4bfa2fb762c4c75bb 324 SMART SM00363 18 83 3.0E-8 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS12120 8bceb513732a67b4bfa2fb762c4c75bb 324 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 15 313 2.8E-100 T 05-07-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS12120 8bceb513732a67b4bfa2fb762c4c75bb 324 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 05-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS12120 8bceb513732a67b4bfa2fb762c4c75bb 324 Pfam PF00849 RNA pseudouridylate synthase 92 241 2.8E-29 T 05-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS12120 8bceb513732a67b4bfa2fb762c4c75bb 324 SUPERFAMILY SSF55120 77 316 4.11E-76 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS12120 8bceb513732a67b4bfa2fb762c4c75bb 324 Gene3D G3DSA:3.10.290.10 18 67 1.0E-9 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS12120 8bceb513732a67b4bfa2fb762c4c75bb 324 SUPERFAMILY SSF55174 17 68 1.85E-9 T 05-07-2017 K08M4_RS12120 8bceb513732a67b4bfa2fb762c4c75bb 324 Pfam PF01479 S4 domain 18 64 1.6E-8 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS12165 dc63d449c1c4b796cb043b37b8ad93de 555 Pfam PF12848 ABC transporter 230 301 4.2E-12 T 05-07-2017 IPR032781 ABC-transporter extension domain K08M4_RS12165 dc63d449c1c4b796cb043b37b8ad93de 555 Gene3D G3DSA:3.40.50.300 8 279 2.0E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12165 dc63d449c1c4b796cb043b37b8ad93de 555 Gene3D G3DSA:3.40.50.300 322 535 7.1E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12165 dc63d449c1c4b796cb043b37b8ad93de 555 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 553 8.8E-293 T 05-07-2017 IPR022374 ABC transporter, ATP-binding protein, ChvD K08M4_RS12165 dc63d449c1c4b796cb043b37b8ad93de 555 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS12165 dc63d449c1c4b796cb043b37b8ad93de 555 SUPERFAMILY SSF52540 9 242 1.4E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12165 dc63d449c1c4b796cb043b37b8ad93de 555 SUPERFAMILY SSF52540 302 527 1.15E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12165 dc63d449c1c4b796cb043b37b8ad93de 555 SMART SM00382 31 236 2.8E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS12165 dc63d449c1c4b796cb043b37b8ad93de 555 SMART SM00382 348 522 1.2E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS12165 dc63d449c1c4b796cb043b37b8ad93de 555 Pfam PF00005 ABC transporter 22 191 8.5E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS12165 dc63d449c1c4b796cb043b37b8ad93de 555 Pfam PF00005 ABC transporter 340 473 5.8E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS13045 9afd6228984ac001d9f2e1c92c3aa9e4 145 Gene3D G3DSA:3.40.50.620 1 144 4.2E-38 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS13045 9afd6228984ac001d9f2e1c92c3aa9e4 145 PIRSF PIRSF006276 1 145 1.1E-19 T 05-07-2017 IPR006015 Universal stress protein A K08M4_RS13045 9afd6228984ac001d9f2e1c92c3aa9e4 145 PRINTS PR01438 Universal stress protein signature 102 114 6.0E-12 T 05-07-2017 IPR006015 Universal stress protein A K08M4_RS13045 9afd6228984ac001d9f2e1c92c3aa9e4 145 PRINTS PR01438 Universal stress protein signature 2 20 6.0E-12 T 05-07-2017 IPR006015 Universal stress protein A K08M4_RS13045 9afd6228984ac001d9f2e1c92c3aa9e4 145 PRINTS PR01438 Universal stress protein signature 120 142 6.0E-12 T 05-07-2017 IPR006015 Universal stress protein A K08M4_RS13045 9afd6228984ac001d9f2e1c92c3aa9e4 145 Pfam PF00582 Universal stress protein family 1 142 3.3E-32 T 05-07-2017 IPR006016 UspA GO:0006950 K08M4_RS13045 9afd6228984ac001d9f2e1c92c3aa9e4 145 SUPERFAMILY SSF52402 2 143 6.28E-36 T 05-07-2017 K08M4_RS01000 bd683bfa65ac475e0087d16d369f52ba 154 Gene3D G3DSA:3.30.70.140 2 97 9.1E-36 T 05-07-2017 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal K08M4_RS01000 bd683bfa65ac475e0087d16d369f52ba 154 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 102 149 5.5E-18 T 05-07-2017 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal K08M4_RS01000 bd683bfa65ac475e0087d16d369f52ba 154 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 7 96 4.6E-30 T 05-07-2017 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal K08M4_RS01000 bd683bfa65ac475e0087d16d369f52ba 154 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 9 99 2.0E-36 T 05-07-2017 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal K08M4_RS01000 bd683bfa65ac475e0087d16d369f52ba 154 SUPERFAMILY SSF54893 2 100 4.05E-35 T 05-07-2017 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal K08M4_RS01000 bd683bfa65ac475e0087d16d369f52ba 154 Gene3D G3DSA:2.30.30.20 101 151 5.2E-21 T 05-07-2017 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal K08M4_RS01000 bd683bfa65ac475e0087d16d369f52ba 154 SUPERFAMILY SSF57825 102 151 1.11E-14 T 05-07-2017 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal K08M4_RS01000 bd683bfa65ac475e0087d16d369f52ba 154 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 4 152 32.613 T 05-07-2017 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 K08M4_RS01000 bd683bfa65ac475e0087d16d369f52ba 154 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 5 150 6.8E-60 T 05-07-2017 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 K08M4_RS03225 b1b6ee013a8aeb49442aa48a6a2e314c 420 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 5 417 1.2E-149 T 05-07-2017 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 K08M4_RS03225 b1b6ee013a8aeb49442aa48a6a2e314c 420 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 197 417 2.3E-72 T 05-07-2017 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 K08M4_RS03225 b1b6ee013a8aeb49442aa48a6a2e314c 420 Pfam PF07670 Nucleoside recognition 95 191 1.7E-6 T 05-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 K08M4_RS03225 b1b6ee013a8aeb49442aa48a6a2e314c 420 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 8.6E-26 T 05-07-2017 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 K08M4_RS05495 0579bb9dcd81147e58783918e2a92657 246 SUPERFAMILY SSF50630 108 242 2.81E-41 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS05495 0579bb9dcd81147e58783918e2a92657 246 Gene3D G3DSA:2.40.70.10 106 236 9.0E-49 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS05495 0579bb9dcd81147e58783918e2a92657 246 Pfam PF05618 Putative ATP-dependant zinc protease 108 243 9.5E-48 T 05-07-2017 K08M4_RS03235 96f9ba4c0b957f1b27d4a12b6ad67658 442 SMART SM00941 350 424 6.5E-26 T 05-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS03235 96f9ba4c0b957f1b27d4a12b6ad67658 442 TIGRFAM TIGR02643 T_phosphoryl: thymidine phosphorylase 3 429 1.4E-210 T 05-07-2017 IPR013465 Thymidine phosphorylase GO:0006213|GO:0009032 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 K08M4_RS03235 96f9ba4c0b957f1b27d4a12b6ad67658 442 Gene3D G3DSA:1.20.970.10 2 67 1.0E-29 T 05-07-2017 K08M4_RS03235 96f9ba4c0b957f1b27d4a12b6ad67658 442 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 350 422 6.1E-23 T 05-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS03235 96f9ba4c0b957f1b27d4a12b6ad67658 442 Gene3D G3DSA:3.90.1170.30 339 432 1.8E-31 T 05-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS03235 96f9ba4c0b957f1b27d4a12b6ad67658 442 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 5 423 1.5E-159 T 05-07-2017 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS03235 96f9ba4c0b957f1b27d4a12b6ad67658 442 PIRSF PIRSF000478 1 438 2.0E-148 T 05-07-2017 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS03235 96f9ba4c0b957f1b27d4a12b6ad67658 442 Hamap MF_01628 Thymidine phosphorylase [deoA]. 1 438 50.62 T 05-07-2017 IPR013465 Thymidine phosphorylase GO:0006213|GO:0009032 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 K08M4_RS03235 96f9ba4c0b957f1b27d4a12b6ad67658 442 Gene3D G3DSA:3.40.1030.10 75 338 9.4E-109 T 05-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS03235 96f9ba4c0b957f1b27d4a12b6ad67658 442 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 113 128 - T 05-07-2017 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS03235 96f9ba4c0b957f1b27d4a12b6ad67658 442 Pfam PF00591 Glycosyl transferase family, a/b domain 80 309 1.3E-48 T 05-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS03235 96f9ba4c0b957f1b27d4a12b6ad67658 442 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 67 1.2E-20 T 05-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS03235 96f9ba4c0b957f1b27d4a12b6ad67658 442 SUPERFAMILY SSF52418 73 334 7.46E-89 T 05-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS03235 96f9ba4c0b957f1b27d4a12b6ad67658 442 SUPERFAMILY SSF47648 2 70 1.24E-21 T 05-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS03235 96f9ba4c0b957f1b27d4a12b6ad67658 442 SUPERFAMILY SSF54680 337 436 8.89E-28 T 05-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS05450 0f94d9a663c13c50c0f82ab19dd5f52e 237 SMART SM00862 158 234 1.3E-18 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS05450 0f94d9a663c13c50c0f82ab19dd5f52e 237 Gene3D G3DSA:3.40.50.2300 2 124 2.8E-36 T 05-07-2017 K08M4_RS05450 0f94d9a663c13c50c0f82ab19dd5f52e 237 SUPERFAMILY SSF46894 136 235 1.3E-25 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS05450 0f94d9a663c13c50c0f82ab19dd5f52e 237 Gene3D G3DSA:1.10.10.10 136 235 6.3E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05450 0f94d9a663c13c50c0f82ab19dd5f52e 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 234 3.2E-20 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS05450 0f94d9a663c13c50c0f82ab19dd5f52e 237 SUPERFAMILY SSF52172 2 125 6.55E-37 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS05450 0f94d9a663c13c50c0f82ab19dd5f52e 237 Pfam PF00072 Response regulator receiver domain 5 113 6.9E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS05450 0f94d9a663c13c50c0f82ab19dd5f52e 237 SMART SM00448 3 113 2.9E-37 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS11910 960da3d734aa1aebf24561485fba4e14 242 Gene3D G3DSA:3.40.1280.10 3 157 2.7E-32 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal K08M4_RS11910 960da3d734aa1aebf24561485fba4e14 242 PIRSF PIRSF004808 1 242 6.0E-73 T 05-07-2017 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 K08M4_RS11910 960da3d734aa1aebf24561485fba4e14 242 Pfam PF00588 SpoU rRNA Methylase family 5 153 1.8E-34 T 05-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 K08M4_RS11910 960da3d734aa1aebf24561485fba4e14 242 SUPERFAMILY SSF75217 4 175 7.19E-37 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases K08M4_RS11910 960da3d734aa1aebf24561485fba4e14 242 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 238 2.2E-82 T 05-07-2017 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 854 0.0 T 05-07-2017 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 SMART SM01086 766 855 3.6E-34 T 05-07-2017 IPR019489 Clp ATPase, C-terminal K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 Pfam PF07724 AAA domain (Cdc48 subfamily) 596 759 1.2E-56 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 3.4E-12 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 3.3E-14 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 SUPERFAMILY SSF52540 159 545 5.66E-101 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 631 649 - T 05-07-2017 IPR028299 ClpA/B, conserved site 2 K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 Gene3D G3DSA:3.40.50.300 160 342 2.4E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 Gene3D G3DSA:3.40.50.300 550 777 3.8E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 Gene3D G3DSA:1.10.8.60 778 854 1.9E-29 T 05-07-2017 K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 845 2.8E-26 T 05-07-2017 IPR019489 Clp ATPase, C-terminal K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 4.3E-42 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 708 722 4.3E-42 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 675 693 4.3E-42 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 601 619 4.3E-42 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 337 2.8E-14 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 SMART SM00382 597 763 5.6E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 SMART SM00382 198 344 1.8E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 SUPERFAMILY SSF81923 4 156 1.44E-42 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 Gene3D G3DSA:1.10.1780.10 1 148 1.4E-45 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 SUPERFAMILY SSF52540 546 853 1.99E-82 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 05-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 K08M4_RS12110 2ec6640cb4d0d7cb53600a780fe89e78 857 Gene3D G3DSA:1.10.8.60 343 428 7.5E-37 T 05-07-2017 K08M4_RS15925 16dcfeddcf7f2a07f9492be4dc81ab05 489 SMART SM00028 207 240 13.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS15925 16dcfeddcf7f2a07f9492be4dc81ab05 489 SMART SM00028 127 160 19.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS15925 16dcfeddcf7f2a07f9492be4dc81ab05 489 SMART SM00028 47 80 34.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS15925 16dcfeddcf7f2a07f9492be4dc81ab05 489 SMART SM00028 247 280 110.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS15925 16dcfeddcf7f2a07f9492be4dc81ab05 489 SUPERFAMILY SSF48452 42 185 9.1E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS15925 16dcfeddcf7f2a07f9492be4dc81ab05 489 Gene3D G3DSA:1.25.40.10 79 349 4.2E-23 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS15925 16dcfeddcf7f2a07f9492be4dc81ab05 489 SUPERFAMILY SSF48452 168 280 5.61E-10 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS05250 35f2b5b70f5032f7337188980238e803 246 ProSitePatterns PS01087 Radical activating enzymes signature. 18 39 - T 05-07-2017 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 K08M4_RS05250 35f2b5b70f5032f7337188980238e803 246 Pfam PF04055 Radical SAM superfamily 24 178 4.3E-31 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS05250 35f2b5b70f5032f7337188980238e803 246 SUPERFAMILY SSF102114 23 220 3.92E-29 T 05-07-2017 K08M4_RS05250 35f2b5b70f5032f7337188980238e803 246 Pfam PF13353 4Fe-4S single cluster domain 16 133 6.0E-20 T 05-07-2017 K08M4_RS05250 35f2b5b70f5032f7337188980238e803 246 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 6 239 3.6E-107 T 05-07-2017 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 K08M4_RS05250 35f2b5b70f5032f7337188980238e803 246 Gene3D G3DSA:3.80.30.10 69 245 5.2E-70 T 05-07-2017 K08M4_RS05075 7bc2520d48e8e3a7a27306780ee9228a 515 Pfam PF00916 Sulfate permease family 13 374 7.6E-57 T 05-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 K08M4_RS05075 7bc2520d48e8e3a7a27306780ee9228a 515 SUPERFAMILY SSF52091 416 497 8.83E-9 T 05-07-2017 IPR002645 STAS domain K08M4_RS05075 7bc2520d48e8e3a7a27306780ee9228a 515 Gene3D G3DSA:3.30.750.24 416 498 2.7E-6 T 05-07-2017 IPR002645 STAS domain K08M4_RS20000 10cdc04ec832e463652cfff55904ae62 336 Pfam PF05125 Phage major capsid protein, P2 family 11 327 5.0E-102 T 05-07-2017 IPR006441 Bacteriophage P2, GpN, major capsid GO:0019028 K08M4_RS20000 10cdc04ec832e463652cfff55904ae62 336 TIGRFAM TIGR01551 major_capsid_P2: phage major capsid protein, P2 family 9 328 4.5E-94 T 05-07-2017 IPR006441 Bacteriophage P2, GpN, major capsid GO:0019028 K08M4_RS03540 b94fcc3fabe705bfd9a10e095a2e47c2 80 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 10 70 15.032 T 05-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 K08M4_RS03540 b94fcc3fabe705bfd9a10e095a2e47c2 80 SUPERFAMILY SSF116842 2 71 2.48E-21 T 05-07-2017 K08M4_RS03540 b94fcc3fabe705bfd9a10e095a2e47c2 80 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 50 4.0E-19 T 05-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 K08M4_RS03540 b94fcc3fabe705bfd9a10e095a2e47c2 80 Gene3D G3DSA:1.10.287.1040 5 77 1.7E-26 T 05-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 K08M4_RS03540 b94fcc3fabe705bfd9a10e095a2e47c2 80 PIRSF PIRSF006488 1 80 8.9E-22 T 05-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 K08M4_RS03540 b94fcc3fabe705bfd9a10e095a2e47c2 80 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 10 65 1.4E-21 T 05-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 K08M4_RS03540 b94fcc3fabe705bfd9a10e095a2e47c2 80 Pfam PF02609 Exonuclease VII small subunit 11 61 4.0E-19 T 05-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 K08M4_RS09435 db74c65c84501e9a51e5e07b4a190bd4 192 Pfam PF00265 Thymidine kinase 2 186 8.2E-59 T 05-07-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 K08M4_RS09435 db74c65c84501e9a51e5e07b4a190bd4 192 SUPERFAMILY SSF57716 142 190 1.24E-15 T 05-07-2017 K08M4_RS09435 db74c65c84501e9a51e5e07b4a190bd4 192 PIRSF PIRSF035805 1 192 2.3E-56 T 05-07-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 K08M4_RS09435 db74c65c84501e9a51e5e07b4a190bd4 192 Gene3D G3DSA:3.40.50.300 14 114 2.1E-4 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09435 db74c65c84501e9a51e5e07b4a190bd4 192 Hamap MF_00124 Thymidine kinase [tdk]. 1 189 34.464 T 05-07-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 K08M4_RS09435 db74c65c84501e9a51e5e07b4a190bd4 192 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 173 186 - T 05-07-2017 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 K08M4_RS09435 db74c65c84501e9a51e5e07b4a190bd4 192 SUPERFAMILY SSF52540 2 141 4.54E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09435 db74c65c84501e9a51e5e07b4a190bd4 192 Gene3D G3DSA:3.30.60.20 142 189 8.3E-18 T 05-07-2017 K08M4_RS19765 85a350ae654c0cc458703d97d867458e 647 SUPERFAMILY SSF58104 338 647 2.09E-66 T 05-07-2017 K08M4_RS19765 85a350ae654c0cc458703d97d867458e 647 Gene3D G3DSA:1.10.287.950 400 617 1.7E-51 T 05-07-2017 K08M4_RS19765 85a350ae654c0cc458703d97d867458e 647 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 449 645 1.1E-46 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS19765 85a350ae654c0cc458703d97d867458e 647 SMART SM00283 385 646 9.7E-63 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS19765 85a350ae654c0cc458703d97d867458e 647 SMART SM01358 36 289 1.1E-39 T 05-07-2017 IPR032255 Helical bimodular sensor domain K08M4_RS19765 85a350ae654c0cc458703d97d867458e 647 Pfam PF00672 HAMP domain 299 366 1.3E-9 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS19765 85a350ae654c0cc458703d97d867458e 647 SMART SM00304 318 370 5.3E-7 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS00230 a0c609662f78b84fb14d780c0538bef3 724 Gene3D G3DSA:3.40.50.300 287 388 2.5E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00230 a0c609662f78b84fb14d780c0538bef3 724 Gene3D G3DSA:3.40.50.300 553 643 2.5E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00230 a0c609662f78b84fb14d780c0538bef3 724 SUPERFAMILY SSF52540 8 643 4.23E-178 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00230 a0c609662f78b84fb14d780c0538bef3 724 Gene3D G3DSA:3.40.50.300 192 286 4.2E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00230 a0c609662f78b84fb14d780c0538bef3 724 Gene3D G3DSA:3.40.50.300 8 111 4.2E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00230 a0c609662f78b84fb14d780c0538bef3 724 Pfam PF13361 UvrD-like helicase C-terminal domain 278 617 2.5E-78 T 05-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 K08M4_RS00230 a0c609662f78b84fb14d780c0538bef3 724 TIGRFAM TIGR01075 uvrD: DNA helicase II 7 722 0.0 T 05-07-2017 IPR005753 DNA helicase, ATP-dependent, UvrD type GO:0004003|GO:0005737|GO:0006268 K08M4_RS00230 a0c609662f78b84fb14d780c0538bef3 724 Gene3D G3DSA:1.10.10.160 115 191 1.4E-21 T 05-07-2017 IPR013986 DExx box DNA helicase domain K08M4_RS00230 a0c609662f78b84fb14d780c0538bef3 724 Gene3D G3DSA:1.10.486.10 389 542 2.5E-48 T 05-07-2017 K08M4_RS00230 a0c609662f78b84fb14d780c0538bef3 724 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 272 3.4E-72 T 05-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 K08M4_RS08970 cf467e68277cacaf418700718c707e17 451 Gene3D G3DSA:3.30.565.10 320 445 6.1E-11 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08970 cf467e68277cacaf418700718c707e17 451 Gene3D G3DSA:3.30.450.20 35 184 6.4E-53 T 05-07-2017 K08M4_RS08970 cf467e68277cacaf418700718c707e17 451 SMART SM00387 353 447 1.6E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08970 cf467e68277cacaf418700718c707e17 451 SMART SM01049 42 133 9.3E-36 T 05-07-2017 IPR033480 Single Cache domain 2 K08M4_RS08970 cf467e68277cacaf418700718c707e17 451 PIRSF PIRSF037314 1 451 6.0E-182 T 05-07-2017 IPR017171 Signal transduction histidine kinase, MctS K08M4_RS08970 cf467e68277cacaf418700718c707e17 451 SUPERFAMILY SSF55874 322 443 4.58E-19 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08970 cf467e68277cacaf418700718c707e17 451 Pfam PF17200 Single Cache domain 2 45 192 5.0E-46 T 05-07-2017 IPR033480 Single Cache domain 2 K08M4_RS08970 cf467e68277cacaf418700718c707e17 451 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 445 7.4E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08970 cf467e68277cacaf418700718c707e17 451 Pfam PF07730 Histidine kinase 250 315 5.4E-13 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 K08M4_RS15025 c6b6e558337dbf76de471a5578c705e8 324 Pfam PF02195 ParB-like nuclease domain 74 138 1.0E-8 T 05-07-2017 IPR003115 ParB/Sulfiredoxin K08M4_RS15025 c6b6e558337dbf76de471a5578c705e8 324 SUPERFAMILY SSF110849 75 150 1.26E-8 T 05-07-2017 IPR003115 ParB/Sulfiredoxin K08M4_RS15025 c6b6e558337dbf76de471a5578c705e8 324 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 67 228 3.8E-23 T 05-07-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 K08M4_RS15025 c6b6e558337dbf76de471a5578c705e8 324 SMART SM00470 58 149 5.2E-7 T 05-07-2017 IPR003115 ParB/Sulfiredoxin K08M4_RS06545 84682197aa778db76ba9f42192ab8537 203 SMART SM00903 19 166 6.4E-4 T 05-07-2017 IPR002563 Flavin reductase like domain GO:0010181 K08M4_RS06545 84682197aa778db76ba9f42192ab8537 203 SUPERFAMILY SSF50475 5 198 3.43E-34 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 K08M4_RS06545 84682197aa778db76ba9f42192ab8537 203 Pfam PF01613 Flavin reductase like domain 22 163 5.9E-18 T 05-07-2017 IPR002563 Flavin reductase like domain GO:0010181 K08M4_RS06545 84682197aa778db76ba9f42192ab8537 203 Gene3D G3DSA:2.30.110.10 11 191 2.1E-55 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 K08M4_RS18500 a614045911f5de6c5477a40901644060 515 SUPERFAMILY SSF52283 1 172 5.1E-53 T 05-07-2017 K08M4_RS18500 a614045911f5de6c5477a40901644060 515 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 141 6.5E-48 T 05-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal K08M4_RS18500 a614045911f5de6c5477a40901644060 515 SMART SM01002 150 315 3.2E-79 T 05-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain K08M4_RS18500 a614045911f5de6c5477a40901644060 515 PIRSF PIRSF000203 1 514 1.1E-269 T 05-07-2017 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 K08M4_RS18500 a614045911f5de6c5477a40901644060 515 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 05-07-2017 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 K08M4_RS18500 a614045911f5de6c5477a40901644060 515 SUPERFAMILY SSF51735 141 318 2.98E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS18500 a614045911f5de6c5477a40901644060 515 SMART SM01003 4 141 2.1E-70 T 05-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal K08M4_RS18500 a614045911f5de6c5477a40901644060 515 TIGRFAM TIGR00561 pntA: NAD(P)(+) transhydrogenase (AB-specific), alpha subunit 2 514 4.9E-276 T 05-07-2017 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 K08M4_RS18500 a614045911f5de6c5477a40901644060 515 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 431 514 5.6E-36 T 05-07-2017 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 K08M4_RS18500 a614045911f5de6c5477a40901644060 515 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 145 372 4.7E-73 T 05-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain K08M4_RS18500 a614045911f5de6c5477a40901644060 515 Gene3D G3DSA:3.40.50.1770 191 375 1.8E-45 T 05-07-2017 K08M4_RS18500 a614045911f5de6c5477a40901644060 515 Gene3D G3DSA:3.40.50.1770 2 190 3.6E-71 T 05-07-2017 K08M4_RS06445 32202011bdea8d1ab4d8b012843e9980 393 Gene3D G3DSA:3.40.640.10 62 275 5.8E-52 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS06445 32202011bdea8d1ab4d8b012843e9980 393 Gene3D G3DSA:3.90.1150.10 276 383 1.8E-13 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS06445 32202011bdea8d1ab4d8b012843e9980 393 Pfam PF00155 Aminotransferase class I and II 45 378 2.0E-32 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS06445 32202011bdea8d1ab4d8b012843e9980 393 SUPERFAMILY SSF53383 34 386 9.04E-73 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 Pfam PF07977 FabA-like domain 1385 1519 6.8E-39 T 05-07-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 Pfam PF07977 FabA-like domain 1846 1980 3.3E-39 T 05-07-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 25 300 9.3E-41 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 501 770 1.1E-23 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 308 425 3.5E-36 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 SUPERFAMILY SSF54637 1137 1315 1.59E-23 T 05-07-2017 IPR029069 HotDog domain K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 SUPERFAMILY SSF53901 750 873 6.48E-5 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 SUPERFAMILY SSF54637 1348 1530 2.61E-29 T 05-07-2017 IPR029069 HotDog domain K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 Gene3D G3DSA:3.10.129.10 1136 1316 3.3E-29 T 05-07-2017 IPR029069 HotDog domain K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 Gene3D G3DSA:3.10.129.10 1602 1788 4.5E-24 T 05-07-2017 IPR029069 HotDog domain K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 Gene3D G3DSA:3.10.129.10 1843 1989 1.5E-53 T 05-07-2017 IPR029069 HotDog domain K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 Gene3D G3DSA:3.10.129.10 1342 1532 8.1E-55 T 05-07-2017 IPR029069 HotDog domain K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 Gene3D G3DSA:3.40.47.10 21 313 5.3E-54 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 SMART SM00825 Beta-ketoacyl synthase 27 480 1.6E-52 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 SUPERFAMILY SSF53901 23 144 9.36E-60 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 SUPERFAMILY SSF53901 196 424 9.36E-60 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 Gene3D G3DSA:3.40.47.10 314 480 4.2E-46 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 SUPERFAMILY SSF53901 644 772 4.51E-26 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 SUPERFAMILY SSF53901 501 616 4.51E-26 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 Gene3D G3DSA:3.40.47.10 502 784 4.1E-28 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 441 518 1.4E-7 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 SUPERFAMILY SSF54637 1606 1788 4.72E-24 T 05-07-2017 IPR029069 HotDog domain K08M4_RS10450 ffcf0afce3e5c49593494ff42ab82ab0 2001 SUPERFAMILY SSF54637 1840 1988 1.45E-28 T 05-07-2017 IPR029069 HotDog domain K08M4_RS06055 2b5320643f3ab4f868115448bced56c2 416 Gene3D G3DSA:2.30.40.10 357 392 1.7E-7 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS06055 2b5320643f3ab4f868115448bced56c2 416 Gene3D G3DSA:2.30.40.10 1 84 1.1E-16 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS06055 2b5320643f3ab4f868115448bced56c2 416 Gene3D G3DSA:3.20.20.140 85 356 9.1E-40 T 05-07-2017 K08M4_RS06055 2b5320643f3ab4f868115448bced56c2 416 SUPERFAMILY SSF51556 73 372 1.5E-85 T 05-07-2017 IPR032466 Metal-dependent hydrolase K08M4_RS06055 2b5320643f3ab4f868115448bced56c2 416 SUPERFAMILY SSF51338 1 73 9.08E-24 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS06055 2b5320643f3ab4f868115448bced56c2 416 SUPERFAMILY SSF51338 374 413 9.08E-24 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS06055 2b5320643f3ab4f868115448bced56c2 416 Hamap MF_00372 Imidazolonepropionase [hutI]. 2 412 41.701 T 05-07-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 K08M4_RS06055 2b5320643f3ab4f868115448bced56c2 416 TIGRFAM TIGR01224 hutI: imidazolonepropionase 26 411 1.8E-151 T 05-07-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 K08M4_RS06055 2b5320643f3ab4f868115448bced56c2 416 Pfam PF01979 Amidohydrolase family 70 393 3.2E-18 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 K08M4_RS01465 a7626d1c4c8c2efffa0ab98cbdf8ff47 209 Gene3D G3DSA:4.10.960.10 77 157 2.2E-38 T 05-07-2017 K08M4_RS01465 a7626d1c4c8c2efffa0ab98cbdf8ff47 209 SUPERFAMILY SSF50447 1 208 1.06E-83 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain K08M4_RS01465 a7626d1c4c8c2efffa0ab98cbdf8ff47 209 Gene3D G3DSA:2.40.30.10 158 207 1.3E-10 T 05-07-2017 K08M4_RS01465 a7626d1c4c8c2efffa0ab98cbdf8ff47 209 Gene3D G3DSA:2.40.30.10 3 32 1.3E-10 T 05-07-2017 K08M4_RS01465 a7626d1c4c8c2efffa0ab98cbdf8ff47 209 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 204 1.7E-94 T 05-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01465 a7626d1c4c8c2efffa0ab98cbdf8ff47 209 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 207 41.317 T 05-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01465 a7626d1c4c8c2efffa0ab98cbdf8ff47 209 ProSitePatterns PS00474 Ribosomal protein L3 signature. 101 124 - T 05-07-2017 IPR019926 Ribosomal protein L3, conserved site K08M4_RS01465 a7626d1c4c8c2efffa0ab98cbdf8ff47 209 Pfam PF00297 Ribosomal protein L3 98 182 1.1E-15 T 05-07-2017 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS06870 ae5b1ad32f3756ebacfcf5f75d39a1cf 419 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 419 143.855 T 05-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 K08M4_RS06870 ae5b1ad32f3756ebacfcf5f75d39a1cf 419 SUPERFAMILY SSF52540 1 418 3.08E-122 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06870 ae5b1ad32f3756ebacfcf5f75d39a1cf 419 Pfam PF00709 Adenylosuccinate synthetase 4 416 7.8E-134 T 05-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 K08M4_RS06870 ae5b1ad32f3756ebacfcf5f75d39a1cf 419 Gene3D G3DSA:3.90.170.10 266 418 1.3E-50 T 05-07-2017 K08M4_RS06870 ae5b1ad32f3756ebacfcf5f75d39a1cf 419 Gene3D G3DSA:1.10.300.10 99 194 5.3E-23 T 05-07-2017 K08M4_RS06870 ae5b1ad32f3756ebacfcf5f75d39a1cf 419 Gene3D G3DSA:3.40.440.10 2 93 4.8E-53 T 05-07-2017 K08M4_RS06870 ae5b1ad32f3756ebacfcf5f75d39a1cf 419 Gene3D G3DSA:3.40.440.10 195 265 4.8E-53 T 05-07-2017 K08M4_RS06870 ae5b1ad32f3756ebacfcf5f75d39a1cf 419 SMART SM00788 3 417 9.9E-183 T 05-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 K08M4_RS01815 46cac2c71da892d5949b05607ea6684a 241 SMART SM00382 28 231 5.9E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS01815 46cac2c71da892d5949b05607ea6684a 241 Gene3D G3DSA:3.40.50.300 3 235 7.2E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01815 46cac2c71da892d5949b05607ea6684a 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 215 236 4.0E-9 T 05-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal K08M4_RS01815 46cac2c71da892d5949b05607ea6684a 241 SUPERFAMILY SSF52540 3 237 2.61E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01815 46cac2c71da892d5949b05607ea6684a 241 Pfam PF00005 ABC transporter 20 166 3.6E-34 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS01815 46cac2c71da892d5949b05607ea6684a 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS01815 46cac2c71da892d5949b05607ea6684a 241 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 4 241 3.3E-124 T 05-07-2017 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 K08M4_RS20790 d34079b373c30527725537773d167b4c 217 Gene3D G3DSA:2.60.120.10 126 216 1.6E-31 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS20790 d34079b373c30527725537773d167b4c 217 Gene3D G3DSA:2.60.120.10 16 125 7.9E-42 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS20790 d34079b373c30527725537773d167b4c 217 Pfam PF12973 ChrR Cupin-like domain 18 108 1.6E-39 T 05-07-2017 IPR025979 ChrR-like cupin domain K08M4_RS20790 d34079b373c30527725537773d167b4c 217 Pfam PF12973 ChrR Cupin-like domain 126 211 1.6E-30 T 05-07-2017 IPR025979 ChrR-like cupin domain K08M4_RS20790 d34079b373c30527725537773d167b4c 217 SUPERFAMILY SSF51182 117 216 5.64E-26 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS20790 d34079b373c30527725537773d167b4c 217 SUPERFAMILY SSF51182 2 128 4.57E-35 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS01530 35cd0f665610348d4447e176d42b6016 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 25.501 T 05-07-2017 IPR023036 Ribosomal protein S14, bacterial/plastid K08M4_RS01530 35cd0f665610348d4447e176d42b6016 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 6.6E-25 T 05-07-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01530 35cd0f665610348d4447e176d42b6016 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 05-07-2017 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01530 35cd0f665610348d4447e176d42b6016 101 SUPERFAMILY SSF57716 2 101 2.35E-36 T 05-07-2017 K08M4_RS01530 35cd0f665610348d4447e176d42b6016 101 Gene3D G3DSA:4.10.830.10 41 101 3.1E-30 T 05-07-2017 K08M4_RS12345 683b8d232add97ee6c161fb228dc5f61 304 Gene3D G3DSA:1.10.443.10 119 296 2.3E-58 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS12345 683b8d232add97ee6c161fb228dc5f61 304 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 10 304 61.354 T 05-07-2017 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 K08M4_RS12345 683b8d232add97ee6c161fb228dc5f61 304 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 12 304 56.108 T 05-07-2017 IPR023009 Tyrosine recombinase XerC/XerD K08M4_RS12345 683b8d232add97ee6c161fb228dc5f61 304 SUPERFAMILY SSF47823 10 106 3.14E-34 T 05-07-2017 IPR010998 Integrase, Lambda-type, N-terminal K08M4_RS12345 683b8d232add97ee6c161fb228dc5f61 304 Gene3D G3DSA:1.10.150.130 13 105 1.1E-27 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal K08M4_RS12345 683b8d232add97ee6c161fb228dc5f61 304 SUPERFAMILY SSF56349 112 302 7.65E-57 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS12345 683b8d232add97ee6c161fb228dc5f61 304 Pfam PF00589 Phage integrase family 119 290 5.2E-53 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS12345 683b8d232add97ee6c161fb228dc5f61 304 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 14 96 1.3E-19 T 05-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 K08M4_RS12345 683b8d232add97ee6c161fb228dc5f61 304 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 15 304 3.8E-116 T 05-07-2017 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 K08M4_RS08595 f43d9f533db25d0d3770526d8a4622e2 364 Pfam PF00266 Aminotransferase class-V 8 352 6.6E-60 T 05-07-2017 IPR000192 Aminotransferase class V domain K08M4_RS08595 f43d9f533db25d0d3770526d8a4622e2 364 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 8 363 1.8E-160 T 05-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 K08M4_RS08595 f43d9f533db25d0d3770526d8a4622e2 364 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 6 363 51.171 T 05-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 K08M4_RS08595 f43d9f533db25d0d3770526d8a4622e2 364 SUPERFAMILY SSF53383 7 362 6.63E-113 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS08595 f43d9f533db25d0d3770526d8a4622e2 364 Gene3D G3DSA:3.40.640.10 21 261 3.7E-103 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS08595 f43d9f533db25d0d3770526d8a4622e2 364 PIRSF PIRSF000525 3 364 1.6E-152 T 05-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 K08M4_RS08595 f43d9f533db25d0d3770526d8a4622e2 364 Gene3D G3DSA:3.90.1150.10 262 363 3.6E-43 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS07545 36d04b8d800a6ade8eece74c565999a3 202 SUPERFAMILY SSF54862 1 183 5.65E-48 T 05-07-2017 K08M4_RS07545 36d04b8d800a6ade8eece74c565999a3 202 Gene3D G3DSA:3.30.70.20 121 181 9.7E-21 T 05-07-2017 K08M4_RS07545 36d04b8d800a6ade8eece74c565999a3 202 Gene3D G3DSA:3.30.70.20 3 64 9.7E-21 T 05-07-2017 K08M4_RS07545 36d04b8d800a6ade8eece74c565999a3 202 Pfam PF13247 4Fe-4S dicluster domain 54 167 3.4E-11 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain K08M4_RS07545 36d04b8d800a6ade8eece74c565999a3 202 Gene3D G3DSA:3.30.70.20 65 120 5.3E-22 T 05-07-2017 K08M4_RS07545 36d04b8d800a6ade8eece74c565999a3 202 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 89 100 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 481 592 3.5E-28 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 Pfam PF00512 His Kinase A (phospho-acceptor) domain 368 433 4.0E-20 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 SUPERFAMILY SSF52172 737 857 4.84E-38 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 SUPERFAMILY SSF47384 353 434 1.61E-21 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 SMART SM00387 480 596 5.3E-38 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 Gene3D G3DSA:1.10.287.130 365 429 1.4E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 PRINTS PR00344 Bacterial sensor protein C-terminal signature 521 535 1.3E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 PRINTS PR00344 Bacterial sensor protein C-terminal signature 556 574 1.3E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 549 1.3E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 PRINTS PR00344 Bacterial sensor protein C-terminal signature 580 593 1.3E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 SUPERFAMILY SSF55874 422 592 3.54E-44 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 SMART SM00448 738 855 1.0E-35 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 Gene3D G3DSA:3.30.565.10 435 596 9.0E-45 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 Gene3D G3DSA:3.40.50.2300 737 857 7.6E-40 T 05-07-2017 K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 SMART SM00388 368 433 2.8E-24 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS16645 70941e222037b6c1e907555e1ea495ef 861 Pfam PF00072 Response regulator receiver domain 740 853 3.0E-22 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS05575 ad80eb5eeb0070352fd5df1fb67ec1f9 450 Pfam PF07676 WD40-like Beta Propeller Repeat 257 292 1.5E-7 T 05-07-2017 IPR011659 WD40-like Beta Propeller K08M4_RS05575 ad80eb5eeb0070352fd5df1fb67ec1f9 450 Pfam PF07676 WD40-like Beta Propeller Repeat 300 335 7.6E-14 T 05-07-2017 IPR011659 WD40-like Beta Propeller K08M4_RS05575 ad80eb5eeb0070352fd5df1fb67ec1f9 450 Pfam PF07676 WD40-like Beta Propeller Repeat 222 248 1.4E-8 T 05-07-2017 IPR011659 WD40-like Beta Propeller K08M4_RS05575 ad80eb5eeb0070352fd5df1fb67ec1f9 450 Gene3D G3DSA:2.130.10.10 173 448 1.9E-75 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 K08M4_RS05575 ad80eb5eeb0070352fd5df1fb67ec1f9 450 SUPERFAMILY SSF52964 29 181 1.96E-40 T 05-07-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 K08M4_RS05575 ad80eb5eeb0070352fd5df1fb67ec1f9 450 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 16 447 2.4E-166 T 05-07-2017 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 K08M4_RS05575 ad80eb5eeb0070352fd5df1fb67ec1f9 450 Gene3D G3DSA:3.40.50.10070 24 172 4.9E-52 T 05-07-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 K08M4_RS05575 ad80eb5eeb0070352fd5df1fb67ec1f9 450 SUPERFAMILY SSF69304 182 448 1.7E-55 T 05-07-2017 K08M4_RS05575 ad80eb5eeb0070352fd5df1fb67ec1f9 450 Pfam PF04052 TolB amino-terminal domain 24 126 9.6E-35 T 05-07-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 K08M4_RS05575 ad80eb5eeb0070352fd5df1fb67ec1f9 450 Hamap MF_00671 Protein TolB [tolB]. 5 446 35.637 T 05-07-2017 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 K08M4_RS11965 02a78f794ed839f3431f49bebcc6a8a8 308 SUPERFAMILY SSF53613 1 301 4.37E-81 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS11965 02a78f794ed839f3431f49bebcc6a8a8 308 PRINTS PR00990 Ribokinase signature 175 190 1.4E-5 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 K08M4_RS11965 02a78f794ed839f3431f49bebcc6a8a8 308 PRINTS PR00990 Ribokinase signature 214 225 1.4E-5 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 K08M4_RS11965 02a78f794ed839f3431f49bebcc6a8a8 308 PRINTS PR00990 Ribokinase signature 22 41 1.4E-5 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 K08M4_RS11965 02a78f794ed839f3431f49bebcc6a8a8 308 Pfam PF00294 pfkB family carbohydrate kinase 1 297 5.4E-67 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB K08M4_RS11965 02a78f794ed839f3431f49bebcc6a8a8 308 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 27 51 - T 05-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 K08M4_RS11965 02a78f794ed839f3431f49bebcc6a8a8 308 Gene3D G3DSA:3.40.1190.20 1 302 4.2E-84 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS11965 02a78f794ed839f3431f49bebcc6a8a8 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 05-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 K08M4_RS09220 7249483e219e0fbfccebee35594bb732 206 Pfam PF01300 Telomere recombination 23 198 1.8E-47 T 05-07-2017 IPR006070 YrdC-like domain GO:0003725 K08M4_RS09220 7249483e219e0fbfccebee35594bb732 206 Gene3D G3DSA:3.90.870.10 2 202 7.4E-67 T 05-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain K08M4_RS09220 7249483e219e0fbfccebee35594bb732 206 SUPERFAMILY SSF55821 1 203 1.83E-65 T 05-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain K08M4_RS09220 7249483e219e0fbfccebee35594bb732 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 7.4E-71 T 05-07-2017 IPR006070 YrdC-like domain GO:0003725 K08M4_RS16960 23d75588900ce08253228d6ff6f4e31e 260 Pfam PF04954 Siderophore-interacting protein 127 241 1.4E-32 T 05-07-2017 IPR007037 Siderophore-interacting protein K08M4_RS16960 23d75588900ce08253228d6ff6f4e31e 260 SUPERFAMILY SSF63380 4 116 2.51E-12 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 K08M4_RS16960 23d75588900ce08253228d6ff6f4e31e 260 Gene3D G3DSA:2.40.30.10 3 117 2.4E-32 T 05-07-2017 K08M4_RS16960 23d75588900ce08253228d6ff6f4e31e 260 Pfam PF08021 Siderophore-interacting FAD-binding domain 10 117 4.1E-28 T 05-07-2017 IPR013113 FAD-binding 9, siderophore-interacting K08M4_RS16960 23d75588900ce08253228d6ff6f4e31e 260 Gene3D G3DSA:3.40.50.80 125 256 1.9E-42 T 05-07-2017 K08M4_RS18930 dae9621692c59771a99cc6db67d6ab35 582 SUPERFAMILY SSF52540 4 580 1.3E-213 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18930 dae9621692c59771a99cc6db67d6ab35 582 Gene3D G3DSA:3.10.410.10 469 558 4.4E-32 T 05-07-2017 K08M4_RS18930 dae9621692c59771a99cc6db67d6ab35 582 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 1 582 42.202 T 05-07-2017 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 K08M4_RS18930 dae9621692c59771a99cc6db67d6ab35 582 Gene3D G3DSA:3.30.1510.10 129 263 7.0E-48 T 05-07-2017 K08M4_RS18930 dae9621692c59771a99cc6db67d6ab35 582 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 103 113 - T 05-07-2017 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 K08M4_RS18930 dae9621692c59771a99cc6db67d6ab35 582 Pfam PF01268 Formate--tetrahydrofolate ligase 3 581 4.5E-237 T 05-07-2017 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 K08M4_RS18930 dae9621692c59771a99cc6db67d6ab35 582 Gene3D G3DSA:3.40.50.300 14 128 3.7E-131 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18930 dae9621692c59771a99cc6db67d6ab35 582 Gene3D G3DSA:3.40.50.300 265 466 3.7E-131 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18930 dae9621692c59771a99cc6db67d6ab35 582 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 345 356 - T 05-07-2017 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 K08M4_RS18960 e58eb6d77dd0f4ae62ca94fc31123177 361 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 248 259 - T 05-07-2017 IPR033116 Serine proteases, trypsin family, serine active site K08M4_RS18960 e58eb6d77dd0f4ae62ca94fc31123177 361 Gene3D G3DSA:2.40.10.10 157 304 5.4E-27 T 05-07-2017 K08M4_RS18960 e58eb6d77dd0f4ae62ca94fc31123177 361 Gene3D G3DSA:2.40.10.10 46 86 1.9E-12 T 05-07-2017 K08M4_RS18960 e58eb6d77dd0f4ae62ca94fc31123177 361 SMART SM00020 45 299 9.2E-34 T 05-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 K08M4_RS18960 e58eb6d77dd0f4ae62ca94fc31123177 361 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 91 96 - T 05-07-2017 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 K08M4_RS18960 e58eb6d77dd0f4ae62ca94fc31123177 361 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 145 159 1.8E-11 T 05-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 K08M4_RS18960 e58eb6d77dd0f4ae62ca94fc31123177 361 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 81 96 1.8E-11 T 05-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 K08M4_RS18960 e58eb6d77dd0f4ae62ca94fc31123177 361 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 247 259 1.8E-11 T 05-07-2017 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 K08M4_RS18960 e58eb6d77dd0f4ae62ca94fc31123177 361 Pfam PF00089 Trypsin 46 299 3.6E-34 T 05-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 K08M4_RS18960 e58eb6d77dd0f4ae62ca94fc31123177 361 SUPERFAMILY SSF50494 13 304 2.28E-54 T 05-07-2017 IPR009003 Peptidase S1, PA clan K08M4_RS18960 e58eb6d77dd0f4ae62ca94fc31123177 361 Gene3D G3DSA:2.40.10.10 87 156 4.3E-17 T 05-07-2017 K08M4_RS14670 1c925d7783de1142b5db431e5c6ea59e 494 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 35 204 3.1E-58 T 05-07-2017 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 K08M4_RS14670 1c925d7783de1142b5db431e5c6ea59e 494 SUPERFAMILY SSF48179 210 341 7.99E-39 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 K08M4_RS14670 1c925d7783de1142b5db431e5c6ea59e 494 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 35 367 3.0E-122 T 05-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 K08M4_RS14670 1c925d7783de1142b5db431e5c6ea59e 494 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 355 485 2.0E-17 T 05-07-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 K08M4_RS14670 1c925d7783de1142b5db431e5c6ea59e 494 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 210 341 9.4E-25 T 05-07-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 K08M4_RS14670 1c925d7783de1142b5db431e5c6ea59e 494 SUPERFAMILY SSF48179 348 487 2.89E-42 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 K08M4_RS14670 1c925d7783de1142b5db431e5c6ea59e 494 Gene3D G3DSA:1.10.1040.10 363 484 2.4E-14 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 K08M4_RS14670 1c925d7783de1142b5db431e5c6ea59e 494 Gene3D G3DSA:3.40.50.720 1 201 4.1E-73 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS14670 1c925d7783de1142b5db431e5c6ea59e 494 SUPERFAMILY SSF51735 28 209 1.66E-56 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS14670 1c925d7783de1142b5db431e5c6ea59e 494 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 22 488 36.779 T 05-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 K08M4_RS19315 ce46753b490057b684bfc11f4baf030a 343 Pfam PF13416 Bacterial extracellular solute-binding protein 72 311 8.8E-15 T 05-07-2017 K08M4_RS19315 ce46753b490057b684bfc11f4baf030a 343 SUPERFAMILY SSF53850 24 340 7.85E-41 T 05-07-2017 K08M4_RS19315 ce46753b490057b684bfc11f4baf030a 343 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 29 45 1.4E-13 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS19315 ce46753b490057b684bfc11f4baf030a 343 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 290 316 1.4E-13 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS19315 ce46753b490057b684bfc11f4baf030a 343 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 245 264 1.4E-13 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS19315 ce46753b490057b684bfc11f4baf030a 343 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 116 132 1.4E-13 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS19315 ce46753b490057b684bfc11f4baf030a 343 Gene3D G3DSA:3.40.190.10 125 293 1.5E-27 T 05-07-2017 K08M4_RS15525 7aa91f3e7d6c61440a771abc5210366e 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.5E-12 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 K08M4_RS15525 7aa91f3e7d6c61440a771abc5210366e 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.5E-12 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 K08M4_RS15525 7aa91f3e7d6c61440a771abc5210366e 261 Gene3D G3DSA:3.30.750.70 77 154 2.7E-13 T 05-07-2017 K08M4_RS15525 7aa91f3e7d6c61440a771abc5210366e 261 SUPERFAMILY SSF46785 5 77 6.28E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15525 7aa91f3e7d6c61440a771abc5210366e 261 SMART SM01134 72 234 4.0E-65 T 05-07-2017 K08M4_RS15525 7aa91f3e7d6c61440a771abc5210366e 261 SMART SM00420 6 58 2.2E-25 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 K08M4_RS15525 7aa91f3e7d6c61440a771abc5210366e 261 Pfam PF08220 DeoR-like helix-turn-helix domain 6 59 2.2E-23 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 K08M4_RS15525 7aa91f3e7d6c61440a771abc5210366e 261 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 05-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 K08M4_RS15525 7aa91f3e7d6c61440a771abc5210366e 261 SUPERFAMILY SSF100950 74 234 2.2E-27 T 05-07-2017 K08M4_RS15525 7aa91f3e7d6c61440a771abc5210366e 261 Pfam PF00455 DeoR C terminal sensor domain 74 232 3.2E-49 T 05-07-2017 IPR014036 DeoR C-terminal sensor domain K08M4_RS15525 7aa91f3e7d6c61440a771abc5210366e 261 Gene3D G3DSA:1.10.10.10 5 55 2.0E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS02765 7bf1458c147922673a106f8d15f0d428 117 PRINTS PR00061 Ribosomal protein L19 signature 88 113 1.1E-41 T 05-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS02765 7bf1458c147922673a106f8d15f0d428 117 PRINTS PR00061 Ribosomal protein L19 signature 34 63 1.1E-41 T 05-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS02765 7bf1458c147922673a106f8d15f0d428 117 PRINTS PR00061 Ribosomal protein L19 signature 4 33 1.1E-41 T 05-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS02765 7bf1458c147922673a106f8d15f0d428 117 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 31.473 T 05-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS02765 7bf1458c147922673a106f8d15f0d428 117 PIRSF PIRSF002191 1 117 1.5E-51 T 05-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS02765 7bf1458c147922673a106f8d15f0d428 117 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 2.8E-52 T 05-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS02765 7bf1458c147922673a106f8d15f0d428 117 SUPERFAMILY SSF50104 2 115 2.01E-47 T 05-07-2017 IPR008991 Translation protein SH3-like domain K08M4_RS02765 7bf1458c147922673a106f8d15f0d428 117 Pfam PF01245 Ribosomal protein L19 3 113 1.3E-50 T 05-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS02765 7bf1458c147922673a106f8d15f0d428 117 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 05-07-2017 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS08835 383dfbfdfcfe72e8856f3071e27c2620 26 Pfam PF11665 Protein of unknown function (DUF3265) 7 26 4.8E-8 T 05-07-2017 IPR021681 Protein of unknown function DUF3265 K08M4_RS08745 c4285ba680db5146c3da6dc447145a66 579 Pfam PF00271 Helicase conserved C-terminal domain 239 343 3.0E-13 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS08745 c4285ba680db5146c3da6dc447145a66 579 Gene3D G3DSA:3.40.50.300 2 154 1.4E-31 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08745 c4285ba680db5146c3da6dc447145a66 579 SUPERFAMILY SSF57829 424 465 2.01E-6 T 05-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 K08M4_RS08745 c4285ba680db5146c3da6dc447145a66 579 Pfam PF04851 Type III restriction enzyme, res subunit 2 154 3.8E-24 T 05-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 K08M4_RS08745 c4285ba680db5146c3da6dc447145a66 579 SUPERFAMILY SSF52540 48 188 2.91E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08745 c4285ba680db5146c3da6dc447145a66 579 SUPERFAMILY SSF52540 236 359 2.91E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08745 c4285ba680db5146c3da6dc447145a66 579 SMART SM00490 262 344 2.3E-11 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS08745 c4285ba680db5146c3da6dc447145a66 579 Gene3D G3DSA:3.40.50.300 235 364 1.3E-21 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08745 c4285ba680db5146c3da6dc447145a66 579 SMART SM00487 1 178 8.8E-14 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS10225 2ecc0f760726e38f81129221c8cc9a86 157 SUPERFAMILY SSF46785 8 95 9.45E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS10225 2ecc0f760726e38f81129221c8cc9a86 157 ProSitePatterns PS00519 AsnC-type HTH domain signature. 26 52 - T 05-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site K08M4_RS10225 2ecc0f760726e38f81129221c8cc9a86 157 Pfam PF01037 Lrp/AsnC ligand binding domain 74 147 2.7E-22 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS10225 2ecc0f760726e38f81129221c8cc9a86 157 SMART SM00344 8 117 1.3E-44 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 K08M4_RS10225 2ecc0f760726e38f81129221c8cc9a86 157 Gene3D G3DSA:1.10.10.10 9 60 1.6E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS10225 2ecc0f760726e38f81129221c8cc9a86 157 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 55 2.0E-16 T 05-07-2017 K08M4_RS10225 2ecc0f760726e38f81129221c8cc9a86 157 Gene3D G3DSA:3.30.70.920 61 145 1.6E-29 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS10225 2ecc0f760726e38f81129221c8cc9a86 157 SUPERFAMILY SSF54909 69 157 1.06E-21 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel K08M4_RS10225 2ecc0f760726e38f81129221c8cc9a86 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 2.1E-11 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS10225 2ecc0f760726e38f81129221c8cc9a86 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 2.1E-11 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS10225 2ecc0f760726e38f81129221c8cc9a86 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 2.1E-11 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS13895 6015a82711f19f8ef1af61154e8e7f7c 273 Gene3D G3DSA:1.10.3130.10 7 142 7.4E-47 T 05-07-2017 K08M4_RS13895 6015a82711f19f8ef1af61154e8e7f7c 273 Pfam PF06426 Serine acetyltransferase, N-terminal 9 112 4.9E-38 T 05-07-2017 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 K08M4_RS13895 6015a82711f19f8ef1af61154e8e7f7c 273 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 82 242 1.4E-73 T 05-07-2017 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 K08M4_RS13895 6015a82711f19f8ef1af61154e8e7f7c 273 SMART SM00971 9 113 8.7E-58 T 05-07-2017 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 K08M4_RS13895 6015a82711f19f8ef1af61154e8e7f7c 273 Gene3D G3DSA:2.160.10.10 143 251 6.4E-31 T 05-07-2017 K08M4_RS13895 6015a82711f19f8ef1af61154e8e7f7c 273 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 202 230 - T 05-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 K08M4_RS13895 6015a82711f19f8ef1af61154e8e7f7c 273 SUPERFAMILY SSF51161 9 258 1.66E-61 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS13895 6015a82711f19f8ef1af61154e8e7f7c 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 193 226 3.5E-9 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS13010 cb0c3bb5a955a07236432662761c41f8 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 7.7E-40 T 05-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13010 cb0c3bb5a955a07236432662761c41f8 103 SUPERFAMILY SSF141091 1 102 2.09E-38 T 05-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13010 cb0c3bb5a955a07236432662761c41f8 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.182 T 05-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13010 cb0c3bb5a955a07236432662761c41f8 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 1.4E-43 T 05-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13010 cb0c3bb5a955a07236432662761c41f8 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 05-07-2017 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS00010 96b01c1691b64fcd9d38b0848a9d24e3 366 Gene3D G3DSA:3.10.150.10 123 248 1.6E-37 T 05-07-2017 K08M4_RS00010 96b01c1691b64fcd9d38b0848a9d24e3 366 Gene3D G3DSA:3.10.150.10 1 121 6.6E-33 T 05-07-2017 K08M4_RS00010 96b01c1691b64fcd9d38b0848a9d24e3 366 SUPERFAMILY SSF55979 126 244 7.33E-29 T 05-07-2017 K08M4_RS00010 96b01c1691b64fcd9d38b0848a9d24e3 366 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 366 1.1E-107 T 05-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS00010 96b01c1691b64fcd9d38b0848a9d24e3 366 SUPERFAMILY SSF55979 1 118 1.08E-29 T 05-07-2017 K08M4_RS00010 96b01c1691b64fcd9d38b0848a9d24e3 366 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 243 4.6E-35 T 05-07-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS00010 96b01c1691b64fcd9d38b0848a9d24e3 366 SMART SM00480 17 362 1.2E-140 T 05-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS00010 96b01c1691b64fcd9d38b0848a9d24e3 366 SUPERFAMILY SSF55979 245 366 3.82E-35 T 05-07-2017 K08M4_RS00010 96b01c1691b64fcd9d38b0848a9d24e3 366 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 119 1.1E-37 T 05-07-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS00010 96b01c1691b64fcd9d38b0848a9d24e3 366 Gene3D G3DSA:3.10.150.10 249 366 2.9E-38 T 05-07-2017 K08M4_RS00010 96b01c1691b64fcd9d38b0848a9d24e3 366 PIRSF PIRSF000804 1 366 5.0E-117 T 05-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS00010 96b01c1691b64fcd9d38b0848a9d24e3 366 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 245 365 4.7E-38 T 05-07-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS10680 066b451dbb1bad1fe6a8946258d1ff35 461 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 153 165 - T 05-07-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 K08M4_RS10680 066b451dbb1bad1fe6a8946258d1ff35 461 SUPERFAMILY SSF103473 8 433 3.27E-39 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS10680 066b451dbb1bad1fe6a8946258d1ff35 461 Gene3D G3DSA:1.20.1250.20 14 204 1.5E-19 T 05-07-2017 K08M4_RS10680 066b451dbb1bad1fe6a8946258d1ff35 461 Gene3D G3DSA:1.20.1250.20 237 433 6.5E-8 T 05-07-2017 K08M4_RS10680 066b451dbb1bad1fe6a8946258d1ff35 461 Pfam PF00854 POT family 228 404 2.8E-30 T 05-07-2017 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 K08M4_RS10680 066b451dbb1bad1fe6a8946258d1ff35 461 Pfam PF00854 POT family 85 197 3.8E-27 T 05-07-2017 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 K08M4_RS10680 066b451dbb1bad1fe6a8946258d1ff35 461 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 230 437 4.7E-43 T 05-07-2017 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 K08M4_RS10680 066b451dbb1bad1fe6a8946258d1ff35 461 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 6 221 5.4E-59 T 05-07-2017 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 K08M4_RS17525 9f8d15ed1a115912a616cde81ddca4ec 194 Gene3D G3DSA:2.60.40.420 74 193 1.7E-23 T 05-07-2017 IPR008972 Cupredoxin K08M4_RS17525 9f8d15ed1a115912a616cde81ddca4ec 194 SUPERFAMILY SSF49503 85 194 6.56E-23 T 05-07-2017 IPR008972 Cupredoxin K08M4_RS04445 53ad2a1b1787f547d2bc622249fc2d36 96 SUPERFAMILY SSF160191 1 91 2.62E-35 T 05-07-2017 K08M4_RS04445 53ad2a1b1787f547d2bc622249fc2d36 96 Pfam PF05166 YcgL domain 3 74 1.0E-31 T 05-07-2017 IPR027354 YcgL domain K08M4_RS04445 53ad2a1b1787f547d2bc622249fc2d36 96 ProDom PD030374 YCGL UNCHARACTERIZED SIMILAR BACTERIA HI1446 Y2231 HYDROLASE CYTOPLASMIC YPO2080 SO2575 1 73 2.0E-30 T 05-07-2017 IPR027354 YcgL domain K08M4_RS04445 53ad2a1b1787f547d2bc622249fc2d36 96 Hamap MF_01866 Protein YcgL [ycgL]. 1 87 27.105 T 05-07-2017 IPR027354 YcgL domain K08M4_RS17210 8601195d8960887159e6f0fbb9db67ba 663 SUPERFAMILY SSF52518 332 525 1.02E-68 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS17210 8601195d8960887159e6f0fbb9db67ba 663 SMART SM00861 353 524 4.8E-68 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain K08M4_RS17210 8601195d8960887159e6f0fbb9db67ba 663 SUPERFAMILY SSF52922 532 663 1.24E-43 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 K08M4_RS17210 8601195d8960887159e6f0fbb9db67ba 663 Gene3D G3DSA:3.40.50.920 537 662 1.7E-50 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 K08M4_RS17210 8601195d8960887159e6f0fbb9db67ba 663 TIGRFAM TIGR00232 tktlase_bact: transketolase 4 662 0.0 T 05-07-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 K08M4_RS17210 8601195d8960887159e6f0fbb9db67ba 663 SUPERFAMILY SSF52518 5 328 2.56E-120 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS17210 8601195d8960887159e6f0fbb9db67ba 663 Gene3D G3DSA:3.40.50.970 4 320 2.7E-134 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS17210 8601195d8960887159e6f0fbb9db67ba 663 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 3 332 7.3E-167 T 05-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS17210 8601195d8960887159e6f0fbb9db67ba 663 Gene3D G3DSA:3.40.50.970 326 532 1.6E-81 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS17210 8601195d8960887159e6f0fbb9db67ba 663 ProSitePatterns PS00802 Transketolase signature 2. 466 482 - T 05-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS17210 8601195d8960887159e6f0fbb9db67ba 663 ProSitePatterns PS00801 Transketolase signature 1. 11 31 - T 05-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS17210 8601195d8960887159e6f0fbb9db67ba 663 Pfam PF02779 Transketolase, pyrimidine binding domain 353 523 1.3E-47 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain K08M4_RS17210 8601195d8960887159e6f0fbb9db67ba 663 Pfam PF02780 Transketolase, C-terminal domain 540 654 3.4E-19 T 05-07-2017 IPR033248 Transketolase, C-terminal domain K08M4_RS20240 3c8a0c53b249144be3eead09d1e1c6a9 271 Gene3D G3DSA:3.40.190.10 25 154 2.0E-42 T 05-07-2017 K08M4_RS20240 3c8a0c53b249144be3eead09d1e1c6a9 271 Pfam PF12727 PBP superfamily domain 40 253 2.5E-38 T 05-07-2017 IPR024370 PBP domain K08M4_RS20240 3c8a0c53b249144be3eead09d1e1c6a9 271 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 10 268 5.6E-64 T 05-07-2017 IPR011862 Phosphate binding protein GO:0006810 K08M4_RS20240 3c8a0c53b249144be3eead09d1e1c6a9 271 SUPERFAMILY SSF53850 25 270 2.97E-63 T 05-07-2017 K08M4_RS01020 14a3aad3b86b88215bf58e0dd78c29cc 303 TIGRFAM TIGR00746 arcC: carbamate kinase 5 302 4.6E-119 T 05-07-2017 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 K08M4_RS01020 14a3aad3b86b88215bf58e0dd78c29cc 303 PIRSF PIRSF000723 2 302 3.6E-113 T 05-07-2017 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 K08M4_RS01020 14a3aad3b86b88215bf58e0dd78c29cc 303 Pfam PF00696 Amino acid kinase family 5 278 1.2E-28 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS01020 14a3aad3b86b88215bf58e0dd78c29cc 303 Gene3D G3DSA:3.40.1160.10 3 302 2.2E-99 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS01020 14a3aad3b86b88215bf58e0dd78c29cc 303 SUPERFAMILY SSF53633 4 300 1.44E-78 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS01020 14a3aad3b86b88215bf58e0dd78c29cc 303 PRINTS PR01469 Bacterial carbamate kinase signature 176 194 2.4E-61 T 05-07-2017 K08M4_RS01020 14a3aad3b86b88215bf58e0dd78c29cc 303 PRINTS PR01469 Bacterial carbamate kinase signature 44 63 2.4E-61 T 05-07-2017 K08M4_RS01020 14a3aad3b86b88215bf58e0dd78c29cc 303 PRINTS PR01469 Bacterial carbamate kinase signature 74 92 2.4E-61 T 05-07-2017 K08M4_RS01020 14a3aad3b86b88215bf58e0dd78c29cc 303 PRINTS PR01469 Bacterial carbamate kinase signature 257 272 2.4E-61 T 05-07-2017 K08M4_RS01020 14a3aad3b86b88215bf58e0dd78c29cc 303 PRINTS PR01469 Bacterial carbamate kinase signature 105 124 2.4E-61 T 05-07-2017 K08M4_RS01020 14a3aad3b86b88215bf58e0dd78c29cc 303 PRINTS PR01469 Bacterial carbamate kinase signature 153 172 2.4E-61 T 05-07-2017 K08M4_RS01020 14a3aad3b86b88215bf58e0dd78c29cc 303 PRINTS PR01469 Bacterial carbamate kinase signature 206 221 2.4E-61 T 05-07-2017 K08M4_RS15845 d4996876abd5c74e3166c03fd18a29af 354 SUPERFAMILY SSF52540 103 319 1.29E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15845 d4996876abd5c74e3166c03fd18a29af 354 Gene3D G3DSA:3.40.50.300 103 257 4.9E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15845 d4996876abd5c74e3166c03fd18a29af 354 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 69 315 1.0E-50 T 05-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 K08M4_RS15845 d4996876abd5c74e3166c03fd18a29af 354 Pfam PF03193 Protein of unknown function, DUF258 85 258 9.6E-48 T 05-07-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 K08M4_RS15845 d4996876abd5c74e3166c03fd18a29af 354 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 35 322 30.886 T 05-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 K08M4_RS15845 d4996876abd5c74e3166c03fd18a29af 354 Gene3D G3DSA:1.10.40.50 263 319 1.0E-21 T 05-07-2017 K08M4_RS06820 9dd19ee6c8adece192a4debcd4a5844c 1153 Gene3D G3DSA:3.40.50.300 719 825 6.7E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06820 9dd19ee6c8adece192a4debcd4a5844c 1153 SMART SM00487 427 652 7.7E-10 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS06820 9dd19ee6c8adece192a4debcd4a5844c 1153 Pfam PF13643 Domain of unknown function (DUF4145) 21 116 3.0E-6 T 05-07-2017 IPR025285 Domain of unknown function DUF4145 K08M4_RS06820 9dd19ee6c8adece192a4debcd4a5844c 1153 Pfam PF08463 EcoEI R protein C-terminal 978 1139 2.3E-29 T 05-07-2017 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 K08M4_RS06820 9dd19ee6c8adece192a4debcd4a5844c 1153 SUPERFAMILY SSF52540 686 829 1.48E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06820 9dd19ee6c8adece192a4debcd4a5844c 1153 SUPERFAMILY SSF52540 444 619 1.48E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06820 9dd19ee6c8adece192a4debcd4a5844c 1153 Gene3D G3DSA:3.40.50.300 549 624 3.3E-22 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06820 9dd19ee6c8adece192a4debcd4a5844c 1153 Gene3D G3DSA:3.40.50.300 428 512 3.3E-22 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06820 9dd19ee6c8adece192a4debcd4a5844c 1153 Pfam PF04851 Type III restriction enzyme, res subunit 428 617 4.1E-33 T 05-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 K08M4_RS06820 9dd19ee6c8adece192a4debcd4a5844c 1153 Pfam PF00271 Helicase conserved C-terminal domain 721 823 6.1E-6 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS06820 9dd19ee6c8adece192a4debcd4a5844c 1153 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 305 369 6.2E-6 T 05-07-2017 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 K08M4_RS21060 afa4d778e4c51facb7e65cf8f1a246a6 725 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 534 722 2.4E-43 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS21060 afa4d778e4c51facb7e65cf8f1a246a6 725 SMART SM00304 393 447 1.5E-6 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS21060 afa4d778e4c51facb7e65cf8f1a246a6 725 SMART SM00283 462 723 1.9E-63 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS21060 afa4d778e4c51facb7e65cf8f1a246a6 725 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 560 587 1.0E-21 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS21060 afa4d778e4c51facb7e65cf8f1a246a6 725 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 589 618 1.0E-21 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS21060 afa4d778e4c51facb7e65cf8f1a246a6 725 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 483 512 1.0E-21 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS21060 afa4d778e4c51facb7e65cf8f1a246a6 725 Gene3D G3DSA:3.30.450.20 217 357 2.8E-11 T 05-07-2017 K08M4_RS21060 afa4d778e4c51facb7e65cf8f1a246a6 725 SUPERFAMILY SSF58104 415 724 4.19E-73 T 05-07-2017 K08M4_RS21060 afa4d778e4c51facb7e65cf8f1a246a6 725 Pfam PF00672 HAMP domain 374 444 4.1E-9 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS21060 afa4d778e4c51facb7e65cf8f1a246a6 725 Gene3D G3DSA:1.10.287.950 477 692 2.6E-53 T 05-07-2017 K08M4_RS03465 2d47f471586e68ddad433d804fcb03a7 154 SUPERFAMILY SSF53271 5 142 1.25E-26 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS03465 2d47f471586e68ddad433d804fcb03a7 154 Hamap MF_01903 Xanthine phosphoribosyltransferase [gpt]. 1 153 37.063 T 05-07-2017 IPR023747 Xanthine-guanine phosphoribosyltransferase GO:0000310 KEGG: 00230+2.4.2.22 K08M4_RS03465 2d47f471586e68ddad433d804fcb03a7 154 Pfam PF00156 Phosphoribosyl transferase domain 32 145 1.3E-12 T 05-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 K08M4_RS03465 2d47f471586e68ddad433d804fcb03a7 154 Gene3D G3DSA:3.40.50.2020 1 145 1.7E-38 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS08660 9623edba92ddb6fcec2648ba61358ed7 87 Pfam PF00462 Glutaredoxin 3 69 1.6E-15 T 05-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 K08M4_RS08660 9623edba92ddb6fcec2648ba61358ed7 87 SUPERFAMILY SSF52833 3 82 5.57E-20 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS08660 9623edba92ddb6fcec2648ba61358ed7 87 Gene3D G3DSA:3.40.30.10 2 82 1.1E-24 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS08660 9623edba92ddb6fcec2648ba61358ed7 87 PRINTS PR00160 Glutaredoxin signature 52 65 5.7E-10 T 05-07-2017 IPR014025 Glutaredoxin subgroup K08M4_RS08660 9623edba92ddb6fcec2648ba61358ed7 87 PRINTS PR00160 Glutaredoxin signature 3 21 5.7E-10 T 05-07-2017 IPR014025 Glutaredoxin subgroup K08M4_RS08660 9623edba92ddb6fcec2648ba61358ed7 87 PRINTS PR00160 Glutaredoxin signature 66 79 5.7E-10 T 05-07-2017 IPR014025 Glutaredoxin subgroup K08M4_RS08660 9623edba92ddb6fcec2648ba61358ed7 87 TIGRFAM TIGR02183 GRXA: glutaredoxin, GrxA family 2 85 1.3E-47 T 05-07-2017 IPR011902 Glutaredoxin, GrxA GO:0009055|GO:0015035|GO:0045454 K08M4_RS02850 2402d4cb3128243dd14eb9696851cd00 219 Pfam PF00484 Carbonic anhydrase 38 188 2.3E-49 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 K08M4_RS02850 2402d4cb3128243dd14eb9696851cd00 219 Gene3D G3DSA:3.40.1050.10 1 209 2.3E-75 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 K08M4_RS02850 2402d4cb3128243dd14eb9696851cd00 219 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 42 49 - T 05-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 K08M4_RS02850 2402d4cb3128243dd14eb9696851cd00 219 SMART SM00947 30 192 2.3E-64 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 K08M4_RS02850 2402d4cb3128243dd14eb9696851cd00 219 SUPERFAMILY SSF53056 2 211 1.7E-72 T 05-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 K08M4_RS02850 2402d4cb3128243dd14eb9696851cd00 219 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 05-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 K08M4_RS15125 c106399798adc20133e6cbaf74a1babb 369 Gene3D G3DSA:2.60.40.1120 326 356 2.7E-4 T 05-07-2017 IPR014766 Carboxypeptidase, regulatory domain K08M4_RS15125 c106399798adc20133e6cbaf74a1babb 369 Pfam PF08308 PEGA domain 298 361 2.8E-22 T 05-07-2017 IPR013229 PEGA K08M4_RS10095 ba29085be5d637e00818113381c99757 134 SUPERFAMILY SSF46458 5 130 6.59E-23 T 05-07-2017 IPR009050 Globin-like K08M4_RS10095 ba29085be5d637e00818113381c99757 134 Gene3D G3DSA:1.10.490.10 2 131 3.1E-32 T 05-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 K08M4_RS09730 55ddee4a95a1efad1af4c81007ce72ef 164 ProSitePatterns PS00519 AsnC-type HTH domain signature. 30 56 - T 05-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site K08M4_RS09730 55ddee4a95a1efad1af4c81007ce72ef 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 9.1E-23 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS09730 55ddee4a95a1efad1af4c81007ce72ef 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 9.1E-23 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS09730 55ddee4a95a1efad1af4c81007ce72ef 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 9.1E-23 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS09730 55ddee4a95a1efad1af4c81007ce72ef 164 Pfam PF13412 Winged helix-turn-helix DNA-binding 12 59 6.1E-22 T 05-07-2017 K08M4_RS09730 55ddee4a95a1efad1af4c81007ce72ef 164 Pfam PF01037 Lrp/AsnC ligand binding domain 78 152 2.7E-23 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS09730 55ddee4a95a1efad1af4c81007ce72ef 164 SUPERFAMILY SSF46785 12 70 1.95E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS09730 55ddee4a95a1efad1af4c81007ce72ef 164 SMART SM00344 12 121 7.3E-55 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 K08M4_RS09730 55ddee4a95a1efad1af4c81007ce72ef 164 Gene3D G3DSA:3.30.70.920 65 161 1.3E-32 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS09730 55ddee4a95a1efad1af4c81007ce72ef 164 Gene3D G3DSA:1.10.10.10 13 64 6.3E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS09730 55ddee4a95a1efad1af4c81007ce72ef 164 SUPERFAMILY SSF54909 74 158 1.34E-21 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel K08M4_RS14910 cbf2e7d55662d1b729044f8c1b04ceb7 467 SUPERFAMILY SSF52540 77 355 1.36E-84 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14910 cbf2e7d55662d1b729044f8c1b04ceb7 467 Gene3D G3DSA:3.40.50.300 76 350 2.5E-104 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14910 cbf2e7d55662d1b729044f8c1b04ceb7 467 Gene3D G3DSA:2.40.10.170 2 75 1.8E-29 T 05-07-2017 K08M4_RS14910 cbf2e7d55662d1b729044f8c1b04ceb7 467 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 340 349 - T 05-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS14910 cbf2e7d55662d1b729044f8c1b04ceb7 467 SUPERFAMILY SSF50615 1 75 1.57E-24 T 05-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS14910 cbf2e7d55662d1b729044f8c1b04ceb7 467 Gene3D G3DSA:1.10.1140.10 352 467 2.1E-50 T 05-07-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS14910 cbf2e7d55662d1b729044f8c1b04ceb7 467 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 467 1.2E-247 T 05-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 K08M4_RS14910 cbf2e7d55662d1b729044f8c1b04ceb7 467 SUPERFAMILY SSF47917 352 466 1.6E-50 T 05-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS14910 cbf2e7d55662d1b729044f8c1b04ceb7 467 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 73 2.8E-20 T 05-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS14910 cbf2e7d55662d1b729044f8c1b04ceb7 467 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 130 349 7.4E-60 T 05-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS14910 cbf2e7d55662d1b729044f8c1b04ceb7 467 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 467 55.717 T 05-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 K08M4_RS14910 cbf2e7d55662d1b729044f8c1b04ceb7 467 SMART SM00382 142 334 8.3E-4 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 Pfam PF00694 Aconitase C-terminal domain 675 805 2.7E-29 T 05-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 28 875 1.1E-291 T 05-07-2017 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 SUPERFAMILY SSF52016 617 875 6.67E-66 T 05-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 Gene3D G3DSA:3.30.499.10 33 248 2.3E-60 T 05-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 Gene3D G3DSA:3.40.1060.10 250 367 2.7E-34 T 05-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 TIGRFAM TIGR02333 2met_isocit_dHY: 2-methylisocitrate dehydratase, Fe/S-dependent 15 877 0.0 T 05-07-2017 IPR012708 2-methylisocitrate dehydratase AcnD, Fe/S-dependent GO:0019679 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 PRINTS PR00415 Aconitase family signature 217 232 6.3E-26 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 PRINTS PR00415 Aconitase family signature 483 496 6.3E-26 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 PRINTS PR00415 Aconitase family signature 279 292 6.3E-26 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 PRINTS PR00415 Aconitase family signature 372 386 6.3E-26 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 PRINTS PR00415 Aconitase family signature 174 182 6.3E-26 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 PRINTS PR00415 Aconitase family signature 203 216 6.3E-26 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 PRINTS PR00415 Aconitase family signature 150 163 6.3E-26 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 PRINTS PR00415 Aconitase family signature 293 306 6.3E-26 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 PRINTS PR00415 Aconitase family signature 421 432 6.3E-26 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 Pfam PF00330 Aconitase family (aconitate hydratase) 82 552 1.5E-150 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 SUPERFAMILY SSF53732 35 610 5.36E-186 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 Gene3D G3DSA:3.20.19.10 623 875 1.6E-62 T 05-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel K08M4_RS08015 4e2deff462daf817ab350cdb3ad75619 878 Gene3D G3DSA:3.30.499.10 368 565 8.1E-57 T 05-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS02245 75071e367c0050a180346ea86dc3c619 276 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 4 233 2.6E-64 T 05-07-2017 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 K08M4_RS02245 75071e367c0050a180346ea86dc3c619 276 Gene3D G3DSA:3.40.1010.10 4 135 2.2E-29 T 05-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS02245 75071e367c0050a180346ea86dc3c619 276 PIRSF PIRSF036427 2 243 1.6E-63 T 05-07-2017 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 K08M4_RS02245 75071e367c0050a180346ea86dc3c619 276 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 222 9.4E-46 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS02245 75071e367c0050a180346ea86dc3c619 276 SUPERFAMILY SSF53790 2 234 4.97E-41 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS20865 61cdc425d0372e0b9505e2113da5809f 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 584 598 5.5E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS20865 61cdc425d0372e0b9505e2113da5809f 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 639 652 5.5E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS20865 61cdc425d0372e0b9505e2113da5809f 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 615 633 5.5E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS20865 61cdc425d0372e0b9505e2113da5809f 657 PRINTS PR00344 Bacterial sensor protein C-terminal signature 602 612 5.5E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS20865 61cdc425d0372e0b9505e2113da5809f 657 Pfam PF00672 HAMP domain 332 398 8.5E-9 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS20865 61cdc425d0372e0b9505e2113da5809f 657 SMART SM00387 545 655 2.3E-32 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS20865 61cdc425d0372e0b9505e2113da5809f 657 Gene3D G3DSA:3.30.565.10 481 653 1.8E-40 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS20865 61cdc425d0372e0b9505e2113da5809f 657 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 547 653 1.1E-23 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS20865 61cdc425d0372e0b9505e2113da5809f 657 SMART SM00388 438 506 0.003 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS20865 61cdc425d0372e0b9505e2113da5809f 657 SUPERFAMILY SSF55874 498 653 9.04E-40 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS20865 61cdc425d0372e0b9505e2113da5809f 657 SUPERFAMILY SSF47384 435 507 9.61E-8 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS16045 e335bbac28f6bdb01ec74df091534747 370 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS16045 e335bbac28f6bdb01ec74df091534747 370 Pfam PF00005 ABC transporter 20 161 1.5E-32 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS16045 e335bbac28f6bdb01ec74df091534747 370 Pfam PF08402 TOBE domain 281 353 5.2E-10 T 05-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 K08M4_RS16045 e335bbac28f6bdb01ec74df091534747 370 Gene3D G3DSA:3.40.50.300 3 236 7.4E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16045 e335bbac28f6bdb01ec74df091534747 370 SMART SM00382 28 211 5.0E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS16045 e335bbac28f6bdb01ec74df091534747 370 Gene3D G3DSA:2.40.50.100 239 287 5.7E-17 T 05-07-2017 K08M4_RS16045 e335bbac28f6bdb01ec74df091534747 370 SUPERFAMILY SSF50331 236 364 3.4E-31 T 05-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal K08M4_RS16045 e335bbac28f6bdb01ec74df091534747 370 Gene3D G3DSA:2.40.50.140 288 345 1.5E-21 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS16045 e335bbac28f6bdb01ec74df091534747 370 SUPERFAMILY SSF52540 4 244 4.41E-85 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19220 b65e1a4cfa258c6098a3022554385f73 560 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 28 503 5.4E-69 T 05-07-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 K08M4_RS19220 b65e1a4cfa258c6098a3022554385f73 560 PIRSF PIRSF031924 1 560 2.5E-189 T 05-07-2017 IPR026263 Alkaline phosphatase, prokaryotic KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 K08M4_RS19220 b65e1a4cfa258c6098a3022554385f73 560 SUPERFAMILY SSF53649 14 109 1.31E-57 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 K08M4_RS19220 b65e1a4cfa258c6098a3022554385f73 560 SUPERFAMILY SSF53649 142 224 1.31E-57 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 K08M4_RS19220 b65e1a4cfa258c6098a3022554385f73 560 SUPERFAMILY SSF53649 275 543 1.31E-57 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 K08M4_RS19220 b65e1a4cfa258c6098a3022554385f73 560 Gene3D G3DSA:3.40.720.10 142 217 1.0E-49 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 K08M4_RS19220 b65e1a4cfa258c6098a3022554385f73 560 Gene3D G3DSA:3.40.720.10 264 392 1.0E-49 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 K08M4_RS19220 b65e1a4cfa258c6098a3022554385f73 560 Gene3D G3DSA:3.40.720.10 9 109 1.0E-49 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 K08M4_RS09390 eb33cb45bcf4c57f8e2dcf61e7eb0ace 820 Gene3D G3DSA:3.90.55.10 505 608 1.5E-33 T 05-07-2017 K08M4_RS09390 eb33cb45bcf4c57f8e2dcf61e7eb0ace 820 Gene3D G3DSA:3.40.228.10 186 395 2.6E-55 T 05-07-2017 K08M4_RS09390 eb33cb45bcf4c57f8e2dcf61e7eb0ace 820 SUPERFAMILY SSF53706 45 660 2.22E-164 T 05-07-2017 K08M4_RS09390 eb33cb45bcf4c57f8e2dcf61e7eb0ace 820 Pfam PF01568 Molydopterin dinucleotide binding domain 676 796 3.7E-24 T 05-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 K08M4_RS09390 eb33cb45bcf4c57f8e2dcf61e7eb0ace 820 Gene3D G3DSA:2.40.40.20 649 812 5.6E-55 T 05-07-2017 K08M4_RS09390 eb33cb45bcf4c57f8e2dcf61e7eb0ace 820 Gene3D G3DSA:3.40.50.740 396 504 3.4E-49 T 05-07-2017 K08M4_RS09390 eb33cb45bcf4c57f8e2dcf61e7eb0ace 820 Gene3D G3DSA:3.40.50.740 81 181 3.4E-49 T 05-07-2017 K08M4_RS09390 eb33cb45bcf4c57f8e2dcf61e7eb0ace 820 SUPERFAMILY SSF50692 669 817 4.52E-42 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain K08M4_RS09390 eb33cb45bcf4c57f8e2dcf61e7eb0ace 820 TIGRFAM TIGR02164 torA: trimethylamine-N-oxide reductase TorA 1 819 0.0 T 05-07-2017 IPR011887 Trimethylamine-N-oxide reductase TorA GO:0030151|GO:0042597|GO:0050626 K08M4_RS09390 eb33cb45bcf4c57f8e2dcf61e7eb0ace 820 Pfam PF00384 Molybdopterin oxidoreductase 87 561 1.8E-80 T 05-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS09390 eb33cb45bcf4c57f8e2dcf61e7eb0ace 820 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 29 3.5E-4 T 05-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal K08M4_RS09390 eb33cb45bcf4c57f8e2dcf61e7eb0ace 820 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 503 520 - T 05-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 Gene3D G3DSA:3.30.450.20 98 196 1.7E-9 T 05-07-2017 K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 Gene3D G3DSA:3.30.565.10 259 427 1.0E-42 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 SMART SM00388 205 272 5.0E-19 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 SUPERFAMILY SSF47384 192 271 1.96E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 426 1.6E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 382 1.6E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 368 1.6E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 407 1.6E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 Pfam PF00989 PAS fold 99 153 3.2E-7 T 05-07-2017 IPR013767 PAS fold GO:0006355 K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 SMART SM00091 98 166 1.3E-5 T 05-07-2017 IPR000014 PAS domain K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 SUPERFAMILY SSF55785 86 197 3.49E-10 T 05-07-2017 IPR000014 PAS domain K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 Pfam PF00512 His Kinase A (phospho-acceptor) domain 205 271 5.3E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 94 425 1.3E-138 T 05-07-2017 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 Gene3D G3DSA:1.10.287.130 197 258 1.0E-19 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 SMART SM00387 317 429 9.5E-35 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 318 427 2.8E-22 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 Pfam PF11808 Domain of unknown function (DUF3329) 7 91 1.6E-31 T 05-07-2017 IPR021766 Protein of unknown function DUF3329 GO:0004673 K08M4_RS12035 27e68cff2d252d0d03fbf438226472d5 432 SUPERFAMILY SSF55874 261 427 1.7E-42 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS18055 7bba0c333ba4022aa74dcea9475bf79c 221 Pfam PF00072 Response regulator receiver domain 4 113 1.3E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS18055 7bba0c333ba4022aa74dcea9475bf79c 221 Gene3D G3DSA:1.10.10.10 148 215 9.5E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS18055 7bba0c333ba4022aa74dcea9475bf79c 221 SMART SM00448 2 112 2.7E-39 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS18055 7bba0c333ba4022aa74dcea9475bf79c 221 Gene3D G3DSA:3.40.50.2300 2 147 2.3E-40 T 05-07-2017 K08M4_RS18055 7bba0c333ba4022aa74dcea9475bf79c 221 SUPERFAMILY SSF52172 2 130 1.39E-39 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS18055 7bba0c333ba4022aa74dcea9475bf79c 221 SMART SM00862 137 215 4.1E-15 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS18055 7bba0c333ba4022aa74dcea9475bf79c 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 141 214 4.8E-17 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS18055 7bba0c333ba4022aa74dcea9475bf79c 221 SUPERFAMILY SSF46894 140 215 1.16E-17 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS18210 7bba0c333ba4022aa74dcea9475bf79c 221 Pfam PF00072 Response regulator receiver domain 4 113 1.3E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS18210 7bba0c333ba4022aa74dcea9475bf79c 221 Gene3D G3DSA:1.10.10.10 148 215 9.5E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS18210 7bba0c333ba4022aa74dcea9475bf79c 221 SMART SM00448 2 112 2.7E-39 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS18210 7bba0c333ba4022aa74dcea9475bf79c 221 Gene3D G3DSA:3.40.50.2300 2 147 2.3E-40 T 05-07-2017 K08M4_RS18210 7bba0c333ba4022aa74dcea9475bf79c 221 SUPERFAMILY SSF52172 2 130 1.39E-39 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS18210 7bba0c333ba4022aa74dcea9475bf79c 221 SMART SM00862 137 215 4.1E-15 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS18210 7bba0c333ba4022aa74dcea9475bf79c 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 141 214 4.8E-17 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS18210 7bba0c333ba4022aa74dcea9475bf79c 221 SUPERFAMILY SSF46894 140 215 1.16E-17 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS12920 473e9229ba2dee75e81eb809a177cc64 515 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 508 42.11 T 05-07-2017 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 K08M4_RS12920 473e9229ba2dee75e81eb809a177cc64 515 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 05-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 K08M4_RS12920 473e9229ba2dee75e81eb809a177cc64 515 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 496 8.3E-236 T 05-07-2017 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 K08M4_RS12920 473e9229ba2dee75e81eb809a177cc64 515 Pfam PF00682 HMGL-like 4 273 9.6E-102 T 05-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 K08M4_RS12920 473e9229ba2dee75e81eb809a177cc64 515 SMART SM00917 369 499 6.2E-28 T 05-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 K08M4_RS12920 473e9229ba2dee75e81eb809a177cc64 515 SUPERFAMILY SSF51569 1 291 2.38E-100 T 05-07-2017 K08M4_RS12920 473e9229ba2dee75e81eb809a177cc64 515 Gene3D G3DSA:3.20.20.70 1 347 6.0E-145 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS12920 473e9229ba2dee75e81eb809a177cc64 515 SUPERFAMILY SSF110921 393 498 3.53E-21 T 05-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 K08M4_RS12920 473e9229ba2dee75e81eb809a177cc64 515 Pfam PF08502 LeuA allosteric (dimerisation) domain 369 498 5.6E-31 T 05-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 K08M4_RS12920 473e9229ba2dee75e81eb809a177cc64 515 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 05-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 K08M4_RS11920 e0367db152b242c3d3965981e2fbd2fb 315 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 40 285 1.4E-85 T 05-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 K08M4_RS11920 e0367db152b242c3d3965981e2fbd2fb 315 Pfam PF07549 SecD/SecF GG Motif 35 60 1.3E-10 T 05-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site K08M4_RS11920 e0367db152b242c3d3965981e2fbd2fb 315 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 11 296 28.908 T 05-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 K08M4_RS11920 e0367db152b242c3d3965981e2fbd2fb 315 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 117 282 8.0E-56 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS11920 e0367db152b242c3d3965981e2fbd2fb 315 SUPERFAMILY SSF82866 74 293 1.12E-40 T 05-07-2017 K08M4_RS11920 e0367db152b242c3d3965981e2fbd2fb 315 Pfam PF02355 Protein export membrane protein 113 292 2.9E-70 T 05-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial K08M4_RS11920 e0367db152b242c3d3965981e2fbd2fb 315 Gene3D G3DSA:1.20.1640.10 129 294 2.2E-26 T 05-07-2017 K08M4_RS11920 e0367db152b242c3d3965981e2fbd2fb 315 PRINTS PR01755 Bacterial translocase SecF protein signature 233 248 1.4E-32 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS11920 e0367db152b242c3d3965981e2fbd2fb 315 PRINTS PR01755 Bacterial translocase SecF protein signature 38 53 1.4E-32 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS11920 e0367db152b242c3d3965981e2fbd2fb 315 PRINTS PR01755 Bacterial translocase SecF protein signature 201 219 1.4E-32 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS11920 e0367db152b242c3d3965981e2fbd2fb 315 PRINTS PR01755 Bacterial translocase SecF protein signature 153 167 1.4E-32 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS12855 f5cf310e2f6ea37f97387157aa76c007 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 9 43 - T 05-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 K08M4_RS12855 f5cf310e2f6ea37f97387157aa76c007 256 Pfam PF08220 DeoR-like helix-turn-helix domain 9 62 2.0E-15 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 K08M4_RS12855 f5cf310e2f6ea37f97387157aa76c007 256 SMART SM00420 9 61 3.0E-14 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 K08M4_RS12855 f5cf310e2f6ea37f97387157aa76c007 256 Pfam PF00455 DeoR C terminal sensor domain 77 233 7.7E-44 T 05-07-2017 IPR014036 DeoR C-terminal sensor domain K08M4_RS12855 f5cf310e2f6ea37f97387157aa76c007 256 Gene3D G3DSA:1.10.10.10 9 58 1.1E-6 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS12855 f5cf310e2f6ea37f97387157aa76c007 256 SMART SM01134 73 234 6.7E-55 T 05-07-2017 K08M4_RS12855 f5cf310e2f6ea37f97387157aa76c007 256 SUPERFAMILY SSF46785 4 63 1.4E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS12855 f5cf310e2f6ea37f97387157aa76c007 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 41 59 1.4E-5 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 K08M4_RS12855 f5cf310e2f6ea37f97387157aa76c007 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 27 41 1.4E-5 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 K08M4_RS12855 f5cf310e2f6ea37f97387157aa76c007 256 Gene3D G3DSA:3.40.50.1360 77 219 1.5E-15 T 05-07-2017 K08M4_RS12855 f5cf310e2f6ea37f97387157aa76c007 256 SUPERFAMILY SSF100950 78 233 4.27E-31 T 05-07-2017 K08M4_RS02240 6eb474adeded11cbb0fc804a7ba9a627 534 SUPERFAMILY SSF159672 1 182 6.28E-54 T 05-07-2017 K08M4_RS02240 6eb474adeded11cbb0fc804a7ba9a627 534 SUPERFAMILY SSF159672 215 247 6.28E-54 T 05-07-2017 K08M4_RS02240 6eb474adeded11cbb0fc804a7ba9a627 534 Gene3D G3DSA:3.30.420.180 233 360 8.3E-32 T 05-07-2017 IPR002750 CobE/GbiG C-terminal domain GO:0009236 K08M4_RS02240 6eb474adeded11cbb0fc804a7ba9a627 534 Pfam PF01890 Cobalamin synthesis G C-terminus 241 351 5.1E-31 T 05-07-2017 IPR002750 CobE/GbiG C-terminal domain GO:0009236 K08M4_RS02240 6eb474adeded11cbb0fc804a7ba9a627 534 Pfam PF11760 Cobalamin synthesis G N-terminal 55 131 1.9E-31 T 05-07-2017 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 K08M4_RS02240 6eb474adeded11cbb0fc804a7ba9a627 534 Gene3D G3DSA:3.40.30.10 413 475 8.6E-10 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS02240 6eb474adeded11cbb0fc804a7ba9a627 534 Pfam PF11761 Cobalamin biosynthesis central region 137 238 5.9E-10 T 05-07-2017 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 K08M4_RS02240 6eb474adeded11cbb0fc804a7ba9a627 534 SUPERFAMILY SSF159664 234 361 4.97E-34 T 05-07-2017 IPR002750 CobE/GbiG C-terminal domain GO:0009236 K08M4_RS02240 6eb474adeded11cbb0fc804a7ba9a627 534 SUPERFAMILY SSF52833 413 473 2.8E-6 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS19265 22f872d6ee4d26dacd2827eaf659a5cc 515 Pfam PF00884 Sulfatase 31 356 5.0E-63 T 05-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 K08M4_RS19265 22f872d6ee4d26dacd2827eaf659a5cc 515 Gene3D G3DSA:3.30.1120.10 411 468 2.0E-10 T 05-07-2017 K08M4_RS19265 22f872d6ee4d26dacd2827eaf659a5cc 515 SUPERFAMILY SSF53649 27 507 8.29E-126 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 K08M4_RS19265 22f872d6ee4d26dacd2827eaf659a5cc 515 Gene3D G3DSA:3.40.720.10 29 410 2.5E-98 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 K08M4_RS19265 22f872d6ee4d26dacd2827eaf659a5cc 515 Pfam PF14707 C-terminal region of aryl-sulfatase 397 494 5.6E-8 T 05-07-2017 K08M4_RS06695 baf41ef3dab09ed56faf45164ba906de 368 Gene3D G3DSA:3.40.630.10 287 367 1.2E-68 T 05-07-2017 K08M4_RS06695 baf41ef3dab09ed56faf45164ba906de 368 Gene3D G3DSA:3.40.630.10 3 177 1.2E-68 T 05-07-2017 K08M4_RS06695 baf41ef3dab09ed56faf45164ba906de 368 SUPERFAMILY SSF53187 7 177 2.46E-57 T 05-07-2017 K08M4_RS06695 baf41ef3dab09ed56faf45164ba906de 368 SUPERFAMILY SSF53187 287 367 2.46E-57 T 05-07-2017 K08M4_RS06695 baf41ef3dab09ed56faf45164ba906de 368 SUPERFAMILY SSF55031 179 289 1.96E-20 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS06695 baf41ef3dab09ed56faf45164ba906de 368 Pfam PF07687 Peptidase dimerisation domain 184 270 4.6E-13 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS06695 baf41ef3dab09ed56faf45164ba906de 368 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 8 367 1.1E-155 T 05-07-2017 IPR010162 Peptidase M20B, peptidase T-like K08M4_RS06695 baf41ef3dab09ed56faf45164ba906de 368 Gene3D G3DSA:3.30.70.360 178 282 2.7E-23 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS06695 baf41ef3dab09ed56faf45164ba906de 368 Pfam PF01546 Peptidase family M20/M25/M40 73 367 5.7E-18 T 05-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 K08M4_RS07880 165aacbf1b333ea1474252f9e1a84586 295 Gene3D G3DSA:3.20.20.60 41 286 5.7E-38 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS07880 165aacbf1b333ea1474252f9e1a84586 295 SUPERFAMILY SSF51621 80 267 1.77E-31 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS07880 165aacbf1b333ea1474252f9e1a84586 295 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 85 265 4.1E-15 T 05-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 K08M4_RS21190 6e7c4a60a69b9ff03c8c7cbaa1da75c2 248 Pfam PF07238 PilZ domain 133 234 3.2E-10 T 05-07-2017 IPR009875 PilZ domain GO:0035438 K08M4_RS21190 6e7c4a60a69b9ff03c8c7cbaa1da75c2 248 Gene3D G3DSA:2.30.110.10 23 135 1.0E-46 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 K08M4_RS21190 6e7c4a60a69b9ff03c8c7cbaa1da75c2 248 Gene3D G3DSA:2.40.10.220 136 246 2.3E-44 T 05-07-2017 K08M4_RS21190 6e7c4a60a69b9ff03c8c7cbaa1da75c2 248 Pfam PF12945 Flagellar protein YcgR 37 126 1.2E-16 T 05-07-2017 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal K08M4_RS21190 6e7c4a60a69b9ff03c8c7cbaa1da75c2 248 SUPERFAMILY SSF141371 23 136 1.53E-33 T 05-07-2017 K08M4_RS21190 6e7c4a60a69b9ff03c8c7cbaa1da75c2 248 SUPERFAMILY SSF141371 137 246 5.49E-31 T 05-07-2017 K08M4_RS16465 099b9cfd9f50976b317f4ab01fa02717 205 SUPERFAMILY SSF52833 109 189 1.8E-18 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS16465 099b9cfd9f50976b317f4ab01fa02717 205 Gene3D G3DSA:3.40.30.10 24 88 4.3E-4 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS16465 099b9cfd9f50976b317f4ab01fa02717 205 Gene3D G3DSA:3.40.30.10 109 184 4.3E-26 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS16465 099b9cfd9f50976b317f4ab01fa02717 205 Pfam PF00462 Glutaredoxin 109 174 1.9E-16 T 05-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 K08M4_RS16465 099b9cfd9f50976b317f4ab01fa02717 205 PRINTS PR00160 Glutaredoxin signature 108 126 1.7E-7 T 05-07-2017 IPR014025 Glutaredoxin subgroup K08M4_RS16465 099b9cfd9f50976b317f4ab01fa02717 205 PRINTS PR00160 Glutaredoxin signature 171 184 1.7E-7 T 05-07-2017 IPR014025 Glutaredoxin subgroup K08M4_RS16465 099b9cfd9f50976b317f4ab01fa02717 205 PRINTS PR00160 Glutaredoxin signature 157 170 1.7E-7 T 05-07-2017 IPR014025 Glutaredoxin subgroup K08M4_RS16465 099b9cfd9f50976b317f4ab01fa02717 205 ProSitePatterns PS00195 Glutaredoxin active site. 110 126 - T 05-07-2017 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 K08M4_RS11935 ac79fb84bd5b06997d4a56fbaef86363 378 Pfam PF01702 Queuine tRNA-ribosyltransferase 128 363 4.6E-96 T 05-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 K08M4_RS11935 ac79fb84bd5b06997d4a56fbaef86363 378 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 5 371 4.5E-179 T 05-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 K08M4_RS11935 ac79fb84bd5b06997d4a56fbaef86363 378 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 5 371 1.2E-187 T 05-07-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 K08M4_RS11935 ac79fb84bd5b06997d4a56fbaef86363 378 Gene3D G3DSA:3.20.20.105 2 369 3.6E-171 T 05-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 K08M4_RS11935 ac79fb84bd5b06997d4a56fbaef86363 378 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 3 361 57.985 T 05-07-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 K08M4_RS11935 ac79fb84bd5b06997d4a56fbaef86363 378 SUPERFAMILY SSF51713 3 367 5.62E-164 T 05-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 K08M4_RS02535 d4ed3ef72195f4b6fe9a41e1fb385880 247 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 232 3.4E-72 T 05-07-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 K08M4_RS02535 d4ed3ef72195f4b6fe9a41e1fb385880 247 Gene3D G3DSA:3.40.1210.10 1 244 2.9E-89 T 05-07-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 K08M4_RS02535 d4ed3ef72195f4b6fe9a41e1fb385880 247 SUPERFAMILY SSF64167 1 245 6.41E-85 T 05-07-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 K08M4_RS02535 d4ed3ef72195f4b6fe9a41e1fb385880 247 Pfam PF01975 Survival protein SurE 3 181 1.5E-58 T 05-07-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 K08M4_RS02535 d4ed3ef72195f4b6fe9a41e1fb385880 247 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 247 40.952 T 05-07-2017 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 K08M4_RS12395 b341dfb5a9b8e241b7266b91c1156000 302 Pfam PF01261 Xylose isomerase-like TIM barrel 33 252 1.4E-40 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain K08M4_RS12395 b341dfb5a9b8e241b7266b91c1156000 302 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 16 290 1.2E-106 T 05-07-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 K08M4_RS12395 b341dfb5a9b8e241b7266b91c1156000 302 SMART SM00518 16 292 2.4E-121 T 05-07-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 K08M4_RS12395 b341dfb5a9b8e241b7266b91c1156000 302 SUPERFAMILY SSF51658 16 289 1.7E-97 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain K08M4_RS12395 b341dfb5a9b8e241b7266b91c1156000 302 Hamap MF_00152 Probable endonuclease 4 [nfo]. 15 292 42.467 T 05-07-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 K08M4_RS12395 b341dfb5a9b8e241b7266b91c1156000 302 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 82 90 - T 05-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 K08M4_RS12395 b341dfb5a9b8e241b7266b91c1156000 302 Gene3D G3DSA:3.20.20.150 15 291 1.6E-118 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain K08M4_RS12395 b341dfb5a9b8e241b7266b91c1156000 302 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 188 195 - T 05-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 K08M4_RS12395 b341dfb5a9b8e241b7266b91c1156000 302 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 228 244 - T 05-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 K08M4_RS00485 a8dcbe33382d6018b5d51c5ce4135e06 406 SUPERFAMILY SSF141868 5 195 3.66E-28 T 05-07-2017 IPR001633 EAL domain K08M4_RS00485 a8dcbe33382d6018b5d51c5ce4135e06 406 Gene3D G3DSA:3.20.20.450 81 183 6.2E-12 T 05-07-2017 IPR001633 EAL domain K08M4_RS00485 a8dcbe33382d6018b5d51c5ce4135e06 406 Gene3D G3DSA:1.10.3150.10 184 401 2.1E-32 T 05-07-2017 IPR013976 Metal-dependent hydrolase HDOD K08M4_RS00485 a8dcbe33382d6018b5d51c5ce4135e06 406 Pfam PF08668 HDOD domain 206 322 1.8E-12 T 05-07-2017 IPR013976 Metal-dependent hydrolase HDOD K08M4_RS00485 a8dcbe33382d6018b5d51c5ce4135e06 406 SMART SM00052 2 197 0.0049 T 05-07-2017 IPR001633 EAL domain K08M4_RS00485 a8dcbe33382d6018b5d51c5ce4135e06 406 PIRSF PIRSF003180 1 406 9.9E-169 T 05-07-2017 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing K08M4_RS00485 a8dcbe33382d6018b5d51c5ce4135e06 406 Pfam PF00563 EAL domain 77 192 2.2E-11 T 05-07-2017 IPR001633 EAL domain K08M4_RS00485 a8dcbe33382d6018b5d51c5ce4135e06 406 SUPERFAMILY SSF109604 183 402 3.77E-41 T 05-07-2017 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 554 685 1.9E-46 T 05-07-2017 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 Gene3D G3DSA:3.40.50.620 183 379 5.7E-90 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 Gene3D G3DSA:3.40.50.620 7 144 5.7E-90 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 SUPERFAMILY SSF50249 585 685 4.65E-32 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 Pfam PF01588 Putative tRNA binding domain 591 683 6.3E-26 T 05-07-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 SUPERFAMILY SSF57770 142 176 4.19E-13 T 05-07-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 SUPERFAMILY SSF52374 5 141 1.31E-101 T 05-07-2017 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 SUPERFAMILY SSF52374 176 387 1.31E-101 T 05-07-2017 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 6.9E-25 T 05-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 PRINTS PR01041 Methionyl-tRNA synthetase signature 251 262 6.9E-25 T 05-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 6.9E-25 T 05-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 PRINTS PR01041 Methionyl-tRNA synthetase signature 291 306 6.9E-25 T 05-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 6.9E-25 T 05-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 PRINTS PR01041 Methionyl-tRNA synthetase signature 384 395 6.9E-25 T 05-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 9 535 6.9E-202 T 05-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 Gene3D G3DSA:2.20.28.20 145 176 3.2E-20 T 05-07-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 Gene3D G3DSA:2.40.50.140 577 685 7.2E-43 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 Hamap MF_00098 Methionine--tRNA ligase [metG]. 6 545 41.53 T 05-07-2017 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 26 - T 05-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 Gene3D G3DSA:1.10.730.10 380 534 1.3E-41 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 Pfam PF09334 tRNA synthetases class I (M) 9 396 5.7E-166 T 05-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS05045 6384fde191778c190c643ac7b7428719 686 SUPERFAMILY SSF47323 389 547 1.91E-44 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS15220 7a871374c09b3ba09aee1f25abffb7a4 398 ProSitePatterns PS00211 ABC transporters family signature. 178 192 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS15220 7a871374c09b3ba09aee1f25abffb7a4 398 SMART SM00382 61 263 5.2E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS15220 7a871374c09b3ba09aee1f25abffb7a4 398 SUPERFAMILY SSF52540 51 283 6.05E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15220 7a871374c09b3ba09aee1f25abffb7a4 398 Pfam PF00005 ABC transporter 52 205 3.7E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS15220 7a871374c09b3ba09aee1f25abffb7a4 398 Gene3D G3DSA:3.40.50.300 13 278 1.3E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15220 7a871374c09b3ba09aee1f25abffb7a4 398 TIGRFAM TIGR03415 ABC_choXWV_ATP: choline ABC transporter, ATP-binding protein 13 396 7.3E-182 T 05-07-2017 IPR022473 ABC transporter, Choline, ATP-binding subunit GO:0015220|GO:0015871|GO:0055052 K08M4_RS15480 41d66a32260d8e88d888887986729da9 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 67 8.8E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS15480 41d66a32260d8e88d888887986729da9 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 9.3E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS15480 41d66a32260d8e88d888887986729da9 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 9.3E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS15480 41d66a32260d8e88d888887986729da9 187 SUPERFAMILY SSF48498 85 180 9.9E-8 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal K08M4_RS15480 41d66a32260d8e88d888887986729da9 187 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 78 161 5.9E-5 T 05-07-2017 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 K08M4_RS15480 41d66a32260d8e88d888887986729da9 187 SUPERFAMILY SSF46689 19 75 1.85E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS15480 41d66a32260d8e88d888887986729da9 187 Gene3D G3DSA:1.10.357.10 10 162 4.6E-29 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS15200 9fe403943bd817db28fc05454115d050 486 Gene3D G3DSA:3.40.605.10 5 260 7.7E-100 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS15200 9fe403943bd817db28fc05454115d050 486 Pfam PF00171 Aldehyde dehydrogenase family 15 474 4.2E-175 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS15200 9fe403943bd817db28fc05454115d050 486 TIGRFAM TIGR01804 BADH: betaine-aldehyde dehydrogenase 7 472 2.1E-204 T 05-07-2017 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 K08M4_RS15200 9fe403943bd817db28fc05454115d050 486 SUPERFAMILY SSF53720 4 480 7.2E-173 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 K08M4_RS15200 9fe403943bd817db28fc05454115d050 486 Gene3D G3DSA:3.40.309.10 261 439 1.2E-68 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 K08M4_RS15200 9fe403943bd817db28fc05454115d050 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 05-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 K08M4_RS15200 9fe403943bd817db28fc05454115d050 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 246 253 - T 05-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 K08M4_RS15200 9fe403943bd817db28fc05454115d050 486 Hamap MF_00804 NAD/NADP-dependent betaine aldehyde dehydrogenase [betB]. 1 486 57.641 T 05-07-2017 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 K08M4_RS11170 d4cad576c22043448ca5a0ff81540a4d 150 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 8 149 36.026 T 05-07-2017 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS11170 d4cad576c22043448ca5a0ff81540a4d 150 Pfam PF07977 FabA-like domain 17 141 1.2E-40 T 05-07-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS11170 d4cad576c22043448ca5a0ff81540a4d 150 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 8 146 1.0E-59 T 05-07-2017 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS11170 d4cad576c22043448ca5a0ff81540a4d 150 SUPERFAMILY SSF54637 6 146 2.16E-49 T 05-07-2017 IPR029069 HotDog domain K08M4_RS11170 d4cad576c22043448ca5a0ff81540a4d 150 Gene3D G3DSA:3.10.129.10 3 147 2.0E-58 T 05-07-2017 IPR029069 HotDog domain K08M4_RS19175 728bace42392ac21a74f48eafbe9ae55 528 Pfam PF00005 ABC transporter 337 478 1.7E-8 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS19175 728bace42392ac21a74f48eafbe9ae55 528 SUPERFAMILY SSF52540 320 516 8.62E-21 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19175 728bace42392ac21a74f48eafbe9ae55 528 Gene3D G3DSA:3.40.50.300 336 516 3.5E-15 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19175 728bace42392ac21a74f48eafbe9ae55 528 Pfam PF00664 ABC transporter transmembrane region 16 282 2.6E-10 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS19175 728bace42392ac21a74f48eafbe9ae55 528 SUPERFAMILY SSF90123 19 310 5.49E-33 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS19175 728bace42392ac21a74f48eafbe9ae55 528 Gene3D G3DSA:1.20.1560.10 19 310 2.8E-30 T 05-07-2017 K08M4_RS19175 728bace42392ac21a74f48eafbe9ae55 528 SMART SM00382 341 520 3.3E-5 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS04605 d78c46bd1d8f585db28d33cb5f1d2ce7 181 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 9 178 37.897 T 05-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 K08M4_RS04605 d78c46bd1d8f585db28d33cb5f1d2ce7 181 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 9 177 1.6E-71 T 05-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 K08M4_RS04605 d78c46bd1d8f585db28d33cb5f1d2ce7 181 SUPERFAMILY SSF53271 10 178 2.84E-51 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS04605 d78c46bd1d8f585db28d33cb5f1d2ce7 181 Gene3D G3DSA:3.40.50.2020 6 179 1.2E-66 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS04605 d78c46bd1d8f585db28d33cb5f1d2ce7 181 Pfam PF00156 Phosphoribosyl transferase domain 32 145 1.0E-13 T 05-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 K08M4_RS01345 d8878e0a441951e655c6edb672cde96a 263 SMART SM01150 3 262 7.8E-112 T 05-07-2017 IPR009770 Domain of unknown function DUF1338 K08M4_RS01345 d8878e0a441951e655c6edb672cde96a 263 Pfam PF07063 Domain of unknown function (DUF1338) 30 116 3.2E-20 T 05-07-2017 IPR009770 Domain of unknown function DUF1338 K08M4_RS01345 d8878e0a441951e655c6edb672cde96a 263 Pfam PF07063 Domain of unknown function (DUF1338) 137 261 9.2E-27 T 05-07-2017 IPR009770 Domain of unknown function DUF1338 K08M4_RS11790 e852adca2a01eb57fc443605f48762f6 566 Pfam PF02839 Carbohydrate binding domain 437 473 3.7E-14 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS11790 e852adca2a01eb57fc443605f48762f6 566 Gene3D G3DSA:2.10.10.20 435 476 2.4E-18 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS11790 e852adca2a01eb57fc443605f48762f6 566 Gene3D G3DSA:1.10.530.10 87 154 2.9E-54 T 05-07-2017 K08M4_RS11790 e852adca2a01eb57fc443605f48762f6 566 Gene3D G3DSA:1.10.530.10 211 349 2.9E-54 T 05-07-2017 K08M4_RS11790 e852adca2a01eb57fc443605f48762f6 566 SUPERFAMILY SSF53955 87 350 7.87E-53 T 05-07-2017 IPR023346 Lysozyme-like domain K08M4_RS11790 e852adca2a01eb57fc443605f48762f6 566 SMART SM00495 434 476 1.2E-15 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS11790 e852adca2a01eb57fc443605f48762f6 566 SMART SM00495 518 563 0.3 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS11790 e852adca2a01eb57fc443605f48762f6 566 SUPERFAMILY SSF51055 435 476 7.72E-15 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS11790 e852adca2a01eb57fc443605f48762f6 566 Pfam PF00182 Chitinase class I 106 325 8.1E-31 T 05-07-2017 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 Pfam PF00488 MutS domain V 609 796 3.0E-87 T 05-07-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 Pfam PF05190 MutS family domain IV 427 517 5.1E-30 T 05-07-2017 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 SUPERFAMILY SSF52540 566 796 1.86E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 Pfam PF05188 MutS domain II 128 253 1.2E-31 T 05-07-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 7 851 0.0 T 05-07-2017 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 Pfam PF05192 MutS domain III 269 558 9.5E-41 T 05-07-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 Gene3D G3DSA:3.30.420.110 127 255 2.1E-41 T 05-07-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 SUPERFAMILY SSF55271 5 115 1.14E-41 T 05-07-2017 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 SUPERFAMILY SSF53150 114 266 1.57E-40 T 05-07-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 Gene3D G3DSA:1.10.1420.10 264 467 9.9E-57 T 05-07-2017 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 PIRSF PIRSF037677 2 832 7.7E-161 T 05-07-2017 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 Pfam PF01624 MutS domain I 8 119 1.7E-41 T 05-07-2017 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 SMART SM00534 606 793 4.5E-119 T 05-07-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 SMART SM00533 283 590 5.9E-105 T 05-07-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 Gene3D G3DSA:3.40.50.300 566 796 1.5E-83 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 7 845 25.41 T 05-07-2017 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 Gene3D G3DSA:3.40.1170.10 4 120 8.8E-51 T 05-07-2017 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 SUPERFAMILY SSF48334 267 564 3.92E-93 T 05-07-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 K08M4_RS02555 c92d1b94df182d61958e545590bbfcb9 853 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 687 703 - T 05-07-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 K08M4_RS13175 6612756ecb3766778def50f9c2e8c94b 557 Pfam PF07655 Secretin N-terminal domain 146 244 1.3E-26 T 05-07-2017 IPR011514 Secretin, N-terminal GO:0009297|GO:0019867 K08M4_RS13175 6612756ecb3766778def50f9c2e8c94b 557 PRINTS PR00811 Bacterial general secretion pathway protein D signature 351 375 2.1E-18 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS13175 6612756ecb3766778def50f9c2e8c94b 557 PRINTS PR00811 Bacterial general secretion pathway protein D signature 273 283 2.1E-18 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS13175 6612756ecb3766778def50f9c2e8c94b 557 PRINTS PR00811 Bacterial general secretion pathway protein D signature 498 516 2.1E-18 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS13175 6612756ecb3766778def50f9c2e8c94b 557 PRINTS PR00811 Bacterial general secretion pathway protein D signature 521 535 2.1E-18 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS13175 6612756ecb3766778def50f9c2e8c94b 557 SMART SM00965 94 142 4.5E-5 T 05-07-2017 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 K08M4_RS13175 6612756ecb3766778def50f9c2e8c94b 557 TIGRFAM TIGR02519 pilus_MshL: pilus (MSHA type) biogenesis protein MshL 239 533 3.5E-96 T 05-07-2017 IPR013358 Pilus biogenesis, MshL K08M4_RS13175 6612756ecb3766778def50f9c2e8c94b 557 Pfam PF00263 Bacterial type II and III secretion system protein 356 533 1.6E-41 T 05-07-2017 IPR004846 Type II/III secretion system GO:0009306 K08M4_RS05780 aabff8d33bc1449f34a7064b77c01048 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 404 433 5.3E-22 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS05780 aabff8d33bc1449f34a7064b77c01048 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 375 402 5.3E-22 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS05780 aabff8d33bc1449f34a7064b77c01048 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 9 34 5.3E-22 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS05780 aabff8d33bc1449f34a7064b77c01048 539 Gene3D G3DSA:1.10.287.950 292 509 4.5E-53 T 05-07-2017 K08M4_RS05780 aabff8d33bc1449f34a7064b77c01048 539 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 324 537 1.1E-44 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS05780 aabff8d33bc1449f34a7064b77c01048 539 SUPERFAMILY SSF58104 230 539 4.05E-71 T 05-07-2017 K08M4_RS05780 aabff8d33bc1449f34a7064b77c01048 539 Pfam PF00672 HAMP domain 189 258 1.3E-9 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS05780 aabff8d33bc1449f34a7064b77c01048 539 SMART SM00283 277 538 2.0E-63 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS05780 aabff8d33bc1449f34a7064b77c01048 539 SMART SM00304 208 262 1.0E-10 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS14975 f25b057fbb70299cdddf0d8582dd5c62 144 Pfam PF00258 Flavodoxin 4 136 1.5E-25 T 05-07-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 K08M4_RS14975 f25b057fbb70299cdddf0d8582dd5c62 144 Gene3D G3DSA:3.40.50.360 2 139 3.1E-37 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS14975 f25b057fbb70299cdddf0d8582dd5c62 144 PRINTS PR00369 Flavodoxin signature 3 16 1.5E-5 T 05-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 K08M4_RS14975 f25b057fbb70299cdddf0d8582dd5c62 144 PRINTS PR00369 Flavodoxin signature 104 123 1.5E-5 T 05-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 K08M4_RS14975 f25b057fbb70299cdddf0d8582dd5c62 144 PRINTS PR00369 Flavodoxin signature 49 60 1.5E-5 T 05-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 K08M4_RS14975 f25b057fbb70299cdddf0d8582dd5c62 144 PRINTS PR00369 Flavodoxin signature 80 90 1.5E-5 T 05-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 K08M4_RS14975 f25b057fbb70299cdddf0d8582dd5c62 144 SUPERFAMILY SSF52218 2 142 3.59E-41 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS07505 9fe00193e3b8bea921d0f896dd31861b 527 Gene3D G3DSA:3.40.50.300 4 100 4.9E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07505 9fe00193e3b8bea921d0f896dd31861b 527 Gene3D G3DSA:3.40.50.300 132 281 4.9E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07505 9fe00193e3b8bea921d0f896dd31861b 527 Pfam PF00005 ABC transporter 18 184 1.2E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS07505 9fe00193e3b8bea921d0f896dd31861b 527 Pfam PF00005 ABC transporter 341 466 3.3E-20 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS07505 9fe00193e3b8bea921d0f896dd31861b 527 SUPERFAMILY SSF52540 4 239 1.92E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07505 9fe00193e3b8bea921d0f896dd31861b 527 Gene3D G3DSA:3.40.50.300 319 525 1.5E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07505 9fe00193e3b8bea921d0f896dd31861b 527 SMART SM00382 343 511 1.3E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS07505 9fe00193e3b8bea921d0f896dd31861b 527 SMART SM00382 26 245 2.4E-6 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS07505 9fe00193e3b8bea921d0f896dd31861b 527 SUPERFAMILY SSF52540 297 521 8.5E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07505 9fe00193e3b8bea921d0f896dd31861b 527 Pfam PF12848 ABC transporter 224 309 6.8E-21 T 05-07-2017 IPR032781 ABC-transporter extension domain K08M4_RS08350 d4f48c6a6f4474b9262b383d40686e18 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 280 1.3E-13 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS08350 d4f48c6a6f4474b9262b383d40686e18 291 SUPERFAMILY SSF161098 52 280 1.7E-44 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS08350 d4f48c6a6f4474b9262b383d40686e18 291 Gene3D G3DSA:1.10.3720.10 6 283 6.0E-46 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 Gene3D G3DSA:3.50.50.60 1 107 6.2E-22 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.9E-18 T 05-07-2017 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 1.9E-18 T 05-07-2017 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 1.9E-18 T 05-07-2017 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.9E-18 T 05-07-2017 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.9E-18 T 05-07-2017 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 4.9E-13 T 05-07-2017 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 4.9E-13 T 05-07-2017 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 4.9E-13 T 05-07-2017 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 280 4.9E-13 T 05-07-2017 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 SUPERFAMILY SSF55424 319 438 6.53E-32 T 05-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 SUPERFAMILY SSF51905 147 312 5.83E-25 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 303 5.7E-50 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 327 428 1.7E-16 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 SUPERFAMILY SSF51905 1 195 1.68E-39 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 Gene3D G3DSA:3.30.390.30 331 439 6.5E-37 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 K08M4_RS20610 475914b9deb6cce8d2ad6ddc6b150db2 440 Gene3D G3DSA:3.50.50.60 108 312 2.2E-41 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS12735 cbbb037ff1aca904dc6fbbe3c5c50fd6 476 Pfam PF01467 Cytidylyltransferase-like 345 469 7.3E-15 T 05-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 K08M4_RS12735 cbbb037ff1aca904dc6fbbe3c5c50fd6 476 SUPERFAMILY SSF52374 340 471 5.35E-23 T 05-07-2017 K08M4_RS12735 cbbb037ff1aca904dc6fbbe3c5c50fd6 476 Gene3D G3DSA:3.40.50.620 340 461 1.6E-34 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS12735 cbbb037ff1aca904dc6fbbe3c5c50fd6 476 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 332 472 3.2E-61 T 05-07-2017 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 K08M4_RS12735 cbbb037ff1aca904dc6fbbe3c5c50fd6 476 Hamap MF_01603 Bifunctional protein HldE [hldE]. 4 474 42.827 T 05-07-2017 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 K08M4_RS12735 cbbb037ff1aca904dc6fbbe3c5c50fd6 476 Gene3D G3DSA:3.40.1190.20 13 312 8.1E-68 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS12735 cbbb037ff1aca904dc6fbbe3c5c50fd6 476 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 342 408 3.3E-17 T 05-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 K08M4_RS12735 cbbb037ff1aca904dc6fbbe3c5c50fd6 476 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 51 74 - T 05-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 K08M4_RS12735 cbbb037ff1aca904dc6fbbe3c5c50fd6 476 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 7 312 2.4E-124 T 05-07-2017 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 K08M4_RS12735 cbbb037ff1aca904dc6fbbe3c5c50fd6 476 Pfam PF00294 pfkB family carbohydrate kinase 13 302 8.9E-49 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB K08M4_RS12735 cbbb037ff1aca904dc6fbbe3c5c50fd6 476 SUPERFAMILY SSF53613 12 304 8.57E-59 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS14045 b9b352b97bf478196ce980e1db3fc88c 238 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 1.9E-112 T 05-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 K08M4_RS14045 b9b352b97bf478196ce980e1db3fc88c 238 Pfam PF03725 3' exoribonuclease family, domain 2 159 224 6.8E-11 T 05-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 K08M4_RS14045 b9b352b97bf478196ce980e1db3fc88c 238 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 05-07-2017 IPR018336 Ribonuclease PH, conserved site K08M4_RS14045 b9b352b97bf478196ce980e1db3fc88c 238 Hamap MF_00564 Ribonuclease PH [rph]. 1 237 48.497 T 05-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 K08M4_RS14045 b9b352b97bf478196ce980e1db3fc88c 238 Gene3D G3DSA:3.30.230.70 7 237 9.3E-37 T 05-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 K08M4_RS14045 b9b352b97bf478196ce980e1db3fc88c 238 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 2.9E-23 T 05-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 K08M4_RS14045 b9b352b97bf478196ce980e1db3fc88c 238 SUPERFAMILY SSF55666 153 237 1.18E-26 T 05-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 K08M4_RS14045 b9b352b97bf478196ce980e1db3fc88c 238 SUPERFAMILY SSF54211 1 181 1.16E-43 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS12230 6049751618fdcf557fd2be620f8f04c7 143 Gene3D G3DSA:3.10.50.40 125 142 9.1E-18 T 05-07-2017 K08M4_RS12230 6049751618fdcf557fd2be620f8f04c7 143 Gene3D G3DSA:3.10.50.40 4 71 9.1E-18 T 05-07-2017 K08M4_RS12230 6049751618fdcf557fd2be620f8f04c7 143 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 4 94 1.9E-12 T 05-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 K08M4_RS12230 6049751618fdcf557fd2be620f8f04c7 143 SUPERFAMILY SSF54534 4 142 2.75E-35 T 05-07-2017 K08M4_RS21355 a9c55144454291704fa3b21811ff2e79 202 ProSitePatterns PS00622 LuxR-type HTH domain signature. 157 184 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS21355 a9c55144454291704fa3b21811ff2e79 202 Gene3D G3DSA:3.40.50.2300 1 116 4.3E-26 T 05-07-2017 K08M4_RS21355 a9c55144454291704fa3b21811ff2e79 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 4.3E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS21355 a9c55144454291704fa3b21811ff2e79 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 4.3E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS21355 a9c55144454291704fa3b21811ff2e79 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 4.3E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS21355 a9c55144454291704fa3b21811ff2e79 202 SUPERFAMILY SSF52172 1 124 3.98E-26 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS21355 a9c55144454291704fa3b21811ff2e79 202 Pfam PF00072 Response regulator receiver domain 4 112 8.0E-22 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS21355 a9c55144454291704fa3b21811ff2e79 202 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 196 5.3E-20 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS21355 a9c55144454291704fa3b21811ff2e79 202 SMART SM00421 140 197 6.0E-20 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS21355 a9c55144454291704fa3b21811ff2e79 202 Gene3D G3DSA:1.10.10.10 117 200 7.9E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21355 a9c55144454291704fa3b21811ff2e79 202 SUPERFAMILY SSF46894 125 199 9.18E-19 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS21355 a9c55144454291704fa3b21811ff2e79 202 SMART SM00448 2 112 5.4E-24 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS13195 0724e4f576a8758e5653358d50a5be91 671 SUPERFAMILY SSF141868 429 637 2.88E-39 T 05-07-2017 IPR001633 EAL domain K08M4_RS13195 0724e4f576a8758e5653358d50a5be91 671 Gene3D G3DSA:3.20.20.450 400 637 1.2E-38 T 05-07-2017 IPR001633 EAL domain K08M4_RS13195 0724e4f576a8758e5653358d50a5be91 671 Pfam PF17157 Gammaproteobacterial periplasmic sensor domain 40 134 1.5E-25 T 05-07-2017 IPR033423 Gammaproteobacterial periplasmic sensor domain GAPES4 K08M4_RS13195 0724e4f576a8758e5653358d50a5be91 671 Pfam PF00990 Diguanylate cyclase, GGDEF domain 229 379 6.8E-19 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS13195 0724e4f576a8758e5653358d50a5be91 671 SMART SM00052 397 638 6.2E-13 T 05-07-2017 IPR001633 EAL domain K08M4_RS13195 0724e4f576a8758e5653358d50a5be91 671 SMART SM00267 216 386 3.0E-7 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS13195 0724e4f576a8758e5653358d50a5be91 671 Pfam PF00563 EAL domain 433 636 1.6E-44 T 05-07-2017 IPR001633 EAL domain K08M4_RS13195 0724e4f576a8758e5653358d50a5be91 671 SUPERFAMILY SSF55073 233 386 2.51E-16 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS13195 0724e4f576a8758e5653358d50a5be91 671 Gene3D G3DSA:3.30.70.270 230 391 2.1E-19 T 05-07-2017 K08M4_RS21780 c92cd72bc6726ccc72d7eb21f7ce8e4e 238 SUPERFAMILY SSF75625 1 237 1.27E-71 T 05-07-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS21780 c92cd72bc6726ccc72d7eb21f7ce8e4e 238 Gene3D G3DSA:3.30.1270.10 80 131 1.8E-33 T 05-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS21780 c92cd72bc6726ccc72d7eb21f7ce8e4e 238 Gene3D G3DSA:3.30.1270.10 211 237 1.8E-33 T 05-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS21780 c92cd72bc6726ccc72d7eb21f7ce8e4e 238 Gene3D G3DSA:3.30.70.980 132 204 3.6E-14 T 05-07-2017 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS21780 c92cd72bc6726ccc72d7eb21f7ce8e4e 238 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 238 26.521 T 05-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS21780 c92cd72bc6726ccc72d7eb21f7ce8e4e 238 Gene3D G3DSA:1.10.10.200 1 78 4.3E-22 T 05-07-2017 IPR017856 Integrase, N-terminal zinc-binding domain-like K08M4_RS21780 c92cd72bc6726ccc72d7eb21f7ce8e4e 238 Pfam PF01709 Transcriptional regulator 5 236 9.3E-69 T 05-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS18035 f7dc3c283b851c76d2a689d4c30aa0b5 271 Pfam PF01226 Formate/nitrite transporter 9 258 2.8E-57 T 05-07-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 K08M4_RS18035 f7dc3c283b851c76d2a689d4c30aa0b5 271 Gene3D G3DSA:1.20.1080.10 26 263 1.2E-61 T 05-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 K08M4_RS07350 cffe6daa6fdfc2024eab2d57865bd9e3 374 SUPERFAMILY SSF53756 22 371 1.57E-54 T 05-07-2017 K08M4_RS07350 cffe6daa6fdfc2024eab2d57865bd9e3 374 Pfam PF00534 Glycosyl transferases group 1 205 350 1.3E-21 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 K08M4_RS07350 cffe6daa6fdfc2024eab2d57865bd9e3 374 Gene3D G3DSA:3.40.50.2000 199 350 3.1E-23 T 05-07-2017 K08M4_RS07350 cffe6daa6fdfc2024eab2d57865bd9e3 374 Pfam PF13579 Glycosyl transferase 4-like domain 28 191 7.4E-15 T 05-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 K08M4_RS06360 587f573011aa04a11dd8d4bf126cb9dc 515 SUPERFAMILY SSF55486 1 405 6.72E-88 T 05-07-2017 K08M4_RS06360 587f573011aa04a11dd8d4bf126cb9dc 515 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 241 260 4.0E-35 T 05-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 K08M4_RS06360 587f573011aa04a11dd8d4bf126cb9dc 515 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 261 280 4.0E-35 T 05-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 K08M4_RS06360 587f573011aa04a11dd8d4bf126cb9dc 515 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 373 390 4.0E-35 T 05-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 K08M4_RS06360 587f573011aa04a11dd8d4bf126cb9dc 515 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 327 346 4.0E-35 T 05-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 K08M4_RS06360 587f573011aa04a11dd8d4bf126cb9dc 515 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 288 304 4.0E-35 T 05-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 K08M4_RS06360 587f573011aa04a11dd8d4bf126cb9dc 515 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 145 165 4.0E-35 T 05-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 K08M4_RS06360 587f573011aa04a11dd8d4bf126cb9dc 515 SUPERFAMILY SSF55486 404 515 7.87E-25 T 05-07-2017 K08M4_RS06360 587f573011aa04a11dd8d4bf126cb9dc 515 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 8 406 1.2E-72 T 05-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 K08M4_RS06360 587f573011aa04a11dd8d4bf126cb9dc 515 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 420 514 8.8E-20 T 05-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 K08M4_RS12000 bf8bf6af5ccac09608f831c199ffd8af 232 SUPERFAMILY SSF109755 10 225 3.03E-71 T 05-07-2017 K08M4_RS12000 bf8bf6af5ccac09608f831c199ffd8af 232 Gene3D G3DSA:1.20.58.220 6 116 2.3E-39 T 05-07-2017 K08M4_RS12000 bf8bf6af5ccac09608f831c199ffd8af 232 PIRSF PIRSF003107 4 223 1.8E-70 T 05-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 K08M4_RS12000 bf8bf6af5ccac09608f831c199ffd8af 232 Pfam PF01895 PhoU domain 23 108 1.1E-22 T 05-07-2017 IPR026022 PhoU domain K08M4_RS12000 bf8bf6af5ccac09608f831c199ffd8af 232 Pfam PF01895 PhoU domain 128 210 6.6E-16 T 05-07-2017 IPR026022 PhoU domain K08M4_RS12000 bf8bf6af5ccac09608f831c199ffd8af 232 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 10 219 1.6E-76 T 05-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 K08M4_RS12000 bf8bf6af5ccac09608f831c199ffd8af 232 Gene3D G3DSA:1.20.58.220 120 226 2.4E-30 T 05-07-2017 K08M4_RS21680 29cb5e624d0ad4cb2723e25d6136a9fd 288 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 35 285 2.7E-45 T 05-07-2017 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 K08M4_RS21680 29cb5e624d0ad4cb2723e25d6136a9fd 288 Gene3D G3DSA:3.40.50.150 1 286 1.3E-69 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS21680 29cb5e624d0ad4cb2723e25d6136a9fd 288 SUPERFAMILY SSF53335 8 286 2.45E-60 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS21680 29cb5e624d0ad4cb2723e25d6136a9fd 288 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 1 277 29.681 T 05-07-2017 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 K08M4_RS12550 bc4b1330c30aa7a3e88e21421fa1ca47 422 PIRSF PIRSF003101 1 422 3.1E-145 T 05-07-2017 IPR020823 Cell division protein FtsA GO:0007049 K08M4_RS12550 bc4b1330c30aa7a3e88e21421fa1ca47 422 Gene3D G3DSA:3.30.420.40 168 208 1.3E-22 T 05-07-2017 K08M4_RS12550 bc4b1330c30aa7a3e88e21421fa1ca47 422 Gene3D G3DSA:3.30.420.40 3 83 1.3E-22 T 05-07-2017 K08M4_RS12550 bc4b1330c30aa7a3e88e21421fa1ca47 422 Gene3D G3DSA:3.90.640.10 235 297 5.5E-19 T 05-07-2017 K08M4_RS12550 bc4b1330c30aa7a3e88e21421fa1ca47 422 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 385 1.1E-149 T 05-07-2017 IPR020823 Cell division protein FtsA GO:0007049 K08M4_RS12550 bc4b1330c30aa7a3e88e21421fa1ca47 422 SUPERFAMILY SSF53067 198 384 5.8E-45 T 05-07-2017 K08M4_RS12550 bc4b1330c30aa7a3e88e21421fa1ca47 422 Gene3D G3DSA:3.30.1490.110 100 165 1.4E-13 T 05-07-2017 K08M4_RS12550 bc4b1330c30aa7a3e88e21421fa1ca47 422 Pfam PF14450 Cell division protein FtsA 207 381 1.4E-23 T 05-07-2017 K08M4_RS12550 bc4b1330c30aa7a3e88e21421fa1ca47 422 SMART SM00842 10 196 1.9E-94 T 05-07-2017 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 K08M4_RS12550 bc4b1330c30aa7a3e88e21421fa1ca47 422 Pfam PF02491 SHS2 domain inserted in FTSA 85 161 3.8E-28 T 05-07-2017 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 K08M4_RS12550 bc4b1330c30aa7a3e88e21421fa1ca47 422 Gene3D G3DSA:3.30.420.40 209 234 6.1E-26 T 05-07-2017 K08M4_RS12550 bc4b1330c30aa7a3e88e21421fa1ca47 422 Gene3D G3DSA:3.30.420.40 298 359 6.1E-26 T 05-07-2017 K08M4_RS12550 bc4b1330c30aa7a3e88e21421fa1ca47 422 SUPERFAMILY SSF53067 8 221 1.57E-60 T 05-07-2017 K08M4_RS12550 bc4b1330c30aa7a3e88e21421fa1ca47 422 Hamap MF_02033 Cell division protein FtsA [ftsA]. 6 422 29.134 T 05-07-2017 IPR020823 Cell division protein FtsA GO:0007049 K08M4_RS21195 98a4c8be572018f6ed989f1b7f6097b2 786 SUPERFAMILY SSF54211 564 756 2.66E-34 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS21195 98a4c8be572018f6ed989f1b7f6097b2 786 Gene3D G3DSA:3.40.50.300 30 88 6.5E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21195 98a4c8be572018f6ed989f1b7f6097b2 786 Gene3D G3DSA:3.40.50.300 314 403 6.5E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21195 98a4c8be572018f6ed989f1b7f6097b2 786 SUPERFAMILY SSF52540 331 537 3.9E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21195 98a4c8be572018f6ed989f1b7f6097b2 786 SUPERFAMILY SSF52540 30 104 3.9E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21195 98a4c8be572018f6ed989f1b7f6097b2 786 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 649 752 3.6E-9 T 05-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 K08M4_RS21195 98a4c8be572018f6ed989f1b7f6097b2 786 Pfam PF13654 AAA domain 25 539 2.8E-183 T 05-07-2017 K08M4_RS21195 98a4c8be572018f6ed989f1b7f6097b2 786 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 676 695 5.5E-7 T 05-07-2017 K08M4_RS21195 98a4c8be572018f6ed989f1b7f6097b2 786 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 706 724 5.5E-7 T 05-07-2017 K08M4_RS21195 98a4c8be572018f6ed989f1b7f6097b2 786 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 646 665 5.5E-7 T 05-07-2017 K08M4_RS21195 98a4c8be572018f6ed989f1b7f6097b2 786 Gene3D G3DSA:3.30.230.10 559 755 2.1E-29 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 PRINTS PR00046 Major sigma-70 factor signature 267 278 1.7E-17 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 PRINTS PR00046 Major sigma-70 factor signature 233 245 1.7E-17 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 PRINTS PR00046 Major sigma-70 factor signature 252 267 1.7E-17 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 PRINTS PR00046 Major sigma-70 factor signature 77 90 1.7E-17 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 Pfam PF00140 Sigma-70 factor, region 1.2 14 40 1.1E-6 T 05-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 77 90 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 252 278 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 2 284 53.425 T 05-07-2017 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 SUPERFAMILY SSF88659 198 282 5.23E-18 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 Pfam PF04545 Sigma-70, region 4 229 280 1.6E-14 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 281 2.4E-33 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 SUPERFAMILY SSF88946 11 122 2.75E-39 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 Gene3D G3DSA:1.10.601.10 11 122 1.4E-33 T 05-07-2017 K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 Pfam PF04542 Sigma-70 region 2 53 122 2.9E-17 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 15 282 6.2E-126 T 05-07-2017 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 K08M4_RS00570 902b376ded071d1d9ab19e475e87addc 285 Gene3D G3DSA:1.10.10.10 226 281 1.1E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 Gene3D G3DSA:3.40.50.280 746 895 4.6E-65 T 05-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 Gene3D G3DSA:3.10.196.10 959 1225 3.4E-107 T 05-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 Pfam PF02607 B12 binding domain 660 734 1.1E-24 T 05-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 SUPERFAMILY SSF51717 357 631 1.19E-86 T 05-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 SMART SM01018 658 741 1.2E-44 T 05-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 SUPERFAMILY SSF52242 746 895 9.94E-45 T 05-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 940 1210 1.7E-122 T 05-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 SUPERFAMILY SSF47644 654 739 2.09E-28 T 05-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 Gene3D G3DSA:1.10.1240.10 653 737 3.1E-39 T 05-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 Gene3D G3DSA:3.20.20.330 4 364 9.4E-127 T 05-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 SUPERFAMILY SSF56507 903 1225 5.36E-129 T 05-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 PIRSF PIRSF000381 3 1197 0.0 T 05-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 Gene3D G3DSA:3.20.20.20 365 636 3.5E-113 T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 Pfam PF00809 Pterin binding enzyme 361 599 2.0E-58 T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 SUPERFAMILY SSF82282 9 400 1.7E-119 T 05-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 Pfam PF02310 B12 binding domain 749 841 3.9E-18 T 05-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 Pfam PF02574 Homocysteine S-methyltransferase 18 326 7.0E-93 T 05-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 K08M4_RS13235 9d754e5ffdfe6b1461091bb9e434e9da 1225 TIGRFAM TIGR02082 metH: methionine synthase 13 1194 0.0 T 05-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS01040 80c514faa210f0b171ab81a62f7d4596 483 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 16 482 5.2E-252 T 05-07-2017 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 K08M4_RS01040 80c514faa210f0b171ab81a62f7d4596 483 Pfam PF00206 Lyase 23 355 3.2E-105 T 05-07-2017 IPR022761 Fumarate lyase, N-terminal K08M4_RS01040 80c514faa210f0b171ab81a62f7d4596 483 Gene3D G3DSA:1.10.275.10 14 152 1.4E-55 T 05-07-2017 IPR024083 Fumarase/histidase, N-terminal K08M4_RS01040 80c514faa210f0b171ab81a62f7d4596 483 Gene3D G3DSA:1.10.40.30 421 472 2.9E-19 T 05-07-2017 K08M4_RS01040 80c514faa210f0b171ab81a62f7d4596 483 Gene3D G3DSA:1.20.200.10 153 415 4.0E-86 T 05-07-2017 K08M4_RS01040 80c514faa210f0b171ab81a62f7d4596 483 Pfam PF10415 Fumarase C C-terminus 421 474 2.3E-17 T 05-07-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 K08M4_RS01040 80c514faa210f0b171ab81a62f7d4596 483 PRINTS PR00149 Fumarate lyase superfamily signature 330 346 2.7E-25 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS01040 80c514faa210f0b171ab81a62f7d4596 483 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 2.7E-25 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS01040 80c514faa210f0b171ab81a62f7d4596 483 PRINTS PR00149 Fumarate lyase superfamily signature 193 211 2.7E-25 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS01040 80c514faa210f0b171ab81a62f7d4596 483 PRINTS PR00149 Fumarate lyase superfamily signature 284 311 2.7E-25 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS01040 80c514faa210f0b171ab81a62f7d4596 483 ProSitePatterns PS00163 Fumarate lyases signature. 330 339 - T 05-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 K08M4_RS01040 80c514faa210f0b171ab81a62f7d4596 483 SUPERFAMILY SSF48557 14 468 9.72E-142 T 05-07-2017 IPR008948 L-Aspartase-like GO:0003824 K08M4_RS00635 04d957564e9d5a4836382f8ac0ac7f1a 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 61 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site K08M4_RS00635 04d957564e9d5a4836382f8ac0ac7f1a 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 61 1.4E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS00635 04d957564e9d5a4836382f8ac0ac7f1a 213 SUPERFAMILY SSF46689 4 80 1.65E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00635 04d957564e9d5a4836382f8ac0ac7f1a 213 Gene3D G3DSA:1.10.357.10 4 195 4.5E-35 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS15445 da50257e4163ef5d4ccf6911bd475b53 479 SUPERFAMILY SSF51445 3 472 7.97E-159 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS15445 da50257e4163ef5d4ccf6911bd475b53 479 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 373 381 - T 05-07-2017 IPR018120 Glycoside hydrolase family 1, active site K08M4_RS15445 da50257e4163ef5d4ccf6911bd475b53 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 394 405 2.5E-16 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 K08M4_RS15445 da50257e4163ef5d4ccf6911bd475b53 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 416 433 2.5E-16 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 K08M4_RS15445 da50257e4163ef5d4ccf6911bd475b53 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 441 453 2.5E-16 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 K08M4_RS15445 da50257e4163ef5d4ccf6911bd475b53 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 305 319 2.5E-16 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 K08M4_RS15445 da50257e4163ef5d4ccf6911bd475b53 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 373 381 2.5E-16 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 K08M4_RS15445 da50257e4163ef5d4ccf6911bd475b53 479 Gene3D G3DSA:3.20.20.80 4 477 3.2E-149 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS15445 da50257e4163ef5d4ccf6911bd475b53 479 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 05-07-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site K08M4_RS15445 da50257e4163ef5d4ccf6911bd475b53 479 Pfam PF00232 Glycosyl hydrolase family 1 2 476 2.1E-136 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 K08M4_RS17335 b65271ae7468208f1c5da16e742b6f92 411 Gene3D G3DSA:3.40.980.10 166 328 1.1E-62 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS17335 b65271ae7468208f1c5da16e742b6f92 411 Pfam PF00994 Probable molybdopterin binding domain 186 320 3.8E-25 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS17335 b65271ae7468208f1c5da16e742b6f92 411 Pfam PF03454 MoeA C-terminal region (domain IV) 336 406 1.2E-20 T 05-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS17335 b65271ae7468208f1c5da16e742b6f92 411 Gene3D G3DSA:2.40.340.10 334 404 1.8E-30 T 05-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS17335 b65271ae7468208f1c5da16e742b6f92 411 SUPERFAMILY SSF63867 332 410 5.76E-23 T 05-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS17335 b65271ae7468208f1c5da16e742b6f92 411 Gene3D G3DSA:2.170.190.11 53 145 1.7E-30 T 05-07-2017 K08M4_RS17335 b65271ae7468208f1c5da16e742b6f92 411 SUPERFAMILY SSF53218 181 326 3.14E-42 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS17335 b65271ae7468208f1c5da16e742b6f92 411 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 257 290 - T 05-07-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 K08M4_RS17335 b65271ae7468208f1c5da16e742b6f92 411 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 180 317 1.4E-32 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS17335 b65271ae7468208f1c5da16e742b6f92 411 Pfam PF03453 MoeA N-terminal region (domain I and II) 11 171 2.4E-37 T 05-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS17335 b65271ae7468208f1c5da16e742b6f92 411 SUPERFAMILY SSF63882 9 179 9.42E-54 T 05-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS17335 b65271ae7468208f1c5da16e742b6f92 411 SMART SM00852 184 321 2.2E-41 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS17335 b65271ae7468208f1c5da16e742b6f92 411 Gene3D G3DSA:3.90.105.10 32 52 3.7E-21 T 05-07-2017 K08M4_RS17335 b65271ae7468208f1c5da16e742b6f92 411 Gene3D G3DSA:3.90.105.10 146 165 3.7E-21 T 05-07-2017 K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 Pfam PF00226 DnaJ domain 5 67 3.5E-26 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 Pfam PF00684 DnaJ central domain 150 210 1.3E-14 T 05-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 Gene3D G3DSA:2.10.230.10 144 213 1.8E-24 T 05-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 SUPERFAMILY SSF57938 137 213 5.23E-23 T 05-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 05-07-2017 IPR018253 DnaJ domain, conserved site K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 SMART SM00271 4 62 1.3E-29 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 376 42.769 T 05-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 Pfam PF01556 DnaJ C terminal domain 124 336 3.5E-45 T 05-07-2017 IPR002939 Chaperone DnaJ, C-terminal K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 Gene3D G3DSA:1.10.287.110 1 105 2.2E-36 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 352 5.1E-140 T 05-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 SUPERFAMILY SSF46565 1 111 8.9E-36 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 SUPERFAMILY SSF49493 117 141 4.19E-20 T 05-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 SUPERFAMILY SSF49493 189 264 4.19E-20 T 05-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 Gene3D G3DSA:2.60.260.20 259 336 2.6E-23 T 05-07-2017 K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 Gene3D G3DSA:2.60.260.20 111 143 3.4E-21 T 05-07-2017 K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 Gene3D G3DSA:2.60.260.20 214 257 3.4E-21 T 05-07-2017 K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 PRINTS PR00625 DnaJ domain signature 25 40 9.4E-32 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 PRINTS PR00625 DnaJ domain signature 62 81 9.4E-32 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 PRINTS PR00625 DnaJ domain signature 7 25 9.4E-32 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 PRINTS PR00625 DnaJ domain signature 42 62 9.4E-32 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS11680 9b1b03fb276c683d8a9551bac2a213dd 382 SUPERFAMILY SSF49493 262 347 4.97E-23 T 05-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 TIGRFAM TIGR02063 RNase_R: ribonuclease R 33 743 1.8E-269 T 05-07-2017 IPR011805 Ribonuclease R GO:0003723|GO:0004518 K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 ProSitePatterns PS01175 Ribonuclease II family signature. 572 596 - T 05-07-2017 IPR022966 Ribonuclease II/R, conserved site K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 SUPERFAMILY SSF50249 661 750 8.9E-22 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 SUPERFAMILY SSF50249 81 164 9.93E-17 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 81 742 7.4E-254 T 05-07-2017 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 SMART SM00316 660 743 3.2E-15 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 SMART SM00357 100 162 1.4E-11 T 05-07-2017 IPR011129 Cold shock protein GO:0003676 K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 Pfam PF00575 S1 RNA binding domain 660 740 7.0E-14 T 05-07-2017 IPR003029 S1 domain GO:0003676 K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 SUPERFAMILY SSF50249 155 253 6.28E-14 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 SMART SM00955 277 605 2.6E-184 T 05-07-2017 K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 SUPERFAMILY SSF50249 237 660 1.88E-142 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 Pfam PF08461 Ribonuclease R winged-helix domain 37 97 1.4E-9 T 05-07-2017 IPR013668 Ribonuclease R winged-helix domain K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 Hamap MF_01895 Ribonuclease R [rnr]. 52 743 58.211 T 05-07-2017 IPR011805 Ribonuclease R GO:0003723|GO:0004518 K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 Pfam PF00773 RNB domain 277 604 6.5E-108 T 05-07-2017 K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 Pfam PF08206 Ribonuclease B OB domain 101 161 1.1E-21 T 05-07-2017 IPR013223 Ribonuclease B, N-terminal OB domain K08M4_RS13480 01b8e6f77e96737bd30cef19e6480f2e 833 Gene3D G3DSA:2.40.50.140 662 755 6.1E-23 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 Gene3D G3DSA:3.30.70.1430 39 141 1.8E-31 T 05-07-2017 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 SUPERFAMILY SSF82693 39 132 1.6E-25 T 05-07-2017 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 Pfam PF00873 AcrB/AcrD/AcrF family 3 1030 0.0 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 SUPERFAMILY SSF82693 136 183 2.22E-21 T 05-07-2017 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 SUPERFAMILY SSF82693 276 332 2.22E-21 T 05-07-2017 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 SUPERFAMILY SSF82866 298 500 7.32E-47 T 05-07-2017 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 Gene3D G3DSA:1.20.1640.10 295 501 4.6E-55 T 05-07-2017 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 SUPERFAMILY SSF82714 184 273 9.29E-23 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 Gene3D G3DSA:3.30.70.1430 567 674 3.0E-27 T 05-07-2017 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 2 1034 0.0 T 05-07-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 2.6E-89 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 2.6E-89 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 2.6E-89 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 PRINTS PR00702 Acriflavin resistance protein family signature 448 471 2.6E-89 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 2.6E-89 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 PRINTS PR00702 Acriflavin resistance protein family signature 473 496 2.6E-89 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 2.6E-89 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 2.6E-89 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 PRINTS PR00702 Acriflavin resistance protein family signature 621 635 2.6E-89 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 Gene3D G3DSA:3.30.2090.10 725 808 7.5E-23 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 Gene3D G3DSA:1.10.3850.10 817 1034 1.6E-56 T 05-07-2017 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 SUPERFAMILY SSF82693 565 674 2.79E-22 T 05-07-2017 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 Gene3D G3DSA:3.30.2090.10 183 274 1.0E-28 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 SUPERFAMILY SSF82866 808 1036 1.83E-43 T 05-07-2017 K08M4_RS20250 42d86c62847dbfcbdb520b7c8f933991 1050 SUPERFAMILY SSF82714 725 808 5.89E-21 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS05340 0c5270bfb78a4644b20d5d240dacacb9 329 Gene3D G3DSA:2.40.160.10 30 329 2.1E-29 T 05-07-2017 IPR023614 Porin domain K08M4_RS05340 0c5270bfb78a4644b20d5d240dacacb9 329 Pfam PF13609 Gram-negative porin 7 303 2.3E-30 T 05-07-2017 K08M4_RS05340 0c5270bfb78a4644b20d5d240dacacb9 329 SUPERFAMILY SSF56935 21 329 6.72E-29 T 05-07-2017 K08M4_RS14800 afc0ab241dce10b99f783c73ab2ee671 426 Pfam PF01189 16S rRNA methyltransferase RsmB/F 238 422 3.1E-67 T 05-07-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS14800 afc0ab241dce10b99f783c73ab2ee671 426 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 313 324 - T 05-07-2017 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS14800 afc0ab241dce10b99f783c73ab2ee671 426 Gene3D G3DSA:1.10.940.10 1 144 1.6E-42 T 05-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 K08M4_RS14800 afc0ab241dce10b99f783c73ab2ee671 426 Gene3D G3DSA:1.10.287.730 145 169 7.1E-13 T 05-07-2017 K08M4_RS14800 afc0ab241dce10b99f783c73ab2ee671 426 SUPERFAMILY SSF53335 138 424 1.27E-75 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS14800 afc0ab241dce10b99f783c73ab2ee671 426 Gene3D G3DSA:3.30.70.1170 170 227 9.7E-26 T 05-07-2017 K08M4_RS14800 afc0ab241dce10b99f783c73ab2ee671 426 Pfam PF01029 NusB family 1 123 5.4E-25 T 05-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 K08M4_RS14800 afc0ab241dce10b99f783c73ab2ee671 426 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 4 426 4.7E-143 T 05-07-2017 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS14800 afc0ab241dce10b99f783c73ab2ee671 426 SUPERFAMILY SSF48013 1 146 6.67E-35 T 05-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 K08M4_RS14800 afc0ab241dce10b99f783c73ab2ee671 426 Gene3D G3DSA:3.40.50.150 229 424 3.0E-56 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS14800 afc0ab241dce10b99f783c73ab2ee671 426 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 407 424 5.4E-30 T 05-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS14800 afc0ab241dce10b99f783c73ab2ee671 426 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 314 326 5.4E-30 T 05-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS14800 afc0ab241dce10b99f783c73ab2ee671 426 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 219 233 5.4E-30 T 05-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS14800 afc0ab241dce10b99f783c73ab2ee671 426 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 248 258 5.4E-30 T 05-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS14800 afc0ab241dce10b99f783c73ab2ee671 426 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 364 380 5.4E-30 T 05-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS05505 feea9d8806834ab8cae3315b2ec08240 242 Hamap MF_01589 Carboxy-S-adenosyl-L-methionine synthase [cmoA]. 3 242 42.856 T 05-07-2017 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 K08M4_RS05505 feea9d8806834ab8cae3315b2ec08240 242 SUPERFAMILY SSF53335 20 242 3.72E-39 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS05505 feea9d8806834ab8cae3315b2ec08240 242 PIRSF PIRSF006325 1 242 2.5E-123 T 05-07-2017 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 K08M4_RS05505 feea9d8806834ab8cae3315b2ec08240 242 Gene3D G3DSA:3.40.50.150 19 241 8.2E-63 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS05505 feea9d8806834ab8cae3315b2ec08240 242 TIGRFAM TIGR00740 TIGR00740: tRNA (cmo5U34)-methyltransferase 4 242 8.1E-116 T 05-07-2017 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 K08M4_RS05505 feea9d8806834ab8cae3315b2ec08240 242 Pfam PF13649 Methyltransferase domain 60 158 4.1E-13 T 05-07-2017 K08M4_RS08630 eb54eb9b833d1f0e34f647ad5b92c03b 306 Pfam PF08668 HDOD domain 39 234 2.9E-34 T 05-07-2017 IPR013976 Metal-dependent hydrolase HDOD K08M4_RS08630 eb54eb9b833d1f0e34f647ad5b92c03b 306 Gene3D G3DSA:1.10.3150.10 17 301 9.1E-53 T 05-07-2017 IPR013976 Metal-dependent hydrolase HDOD K08M4_RS08630 eb54eb9b833d1f0e34f647ad5b92c03b 306 SUPERFAMILY SSF109604 33 301 1.19E-38 T 05-07-2017 K08M4_RS14920 0ad00c39d8b347992dac7bdc00e9b095 513 Gene3D G3DSA:1.20.150.20 383 510 8.9E-48 T 05-07-2017 K08M4_RS14920 0ad00c39d8b347992dac7bdc00e9b095 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 7.3E-72 T 05-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS14920 0ad00c39d8b347992dac7bdc00e9b095 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 05-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS14920 0ad00c39d8b347992dac7bdc00e9b095 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 2.5E-44 T 05-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS14920 0ad00c39d8b347992dac7bdc00e9b095 513 SUPERFAMILY SSF50615 10 94 1.14E-24 T 05-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS14920 0ad00c39d8b347992dac7bdc00e9b095 513 Gene3D G3DSA:3.40.50.300 94 382 6.6E-112 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14920 0ad00c39d8b347992dac7bdc00e9b095 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 49.28 T 05-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 K08M4_RS14920 0ad00c39d8b347992dac7bdc00e9b095 513 SUPERFAMILY SSF47917 383 511 1.26E-45 T 05-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS14920 0ad00c39d8b347992dac7bdc00e9b095 513 Gene3D G3DSA:2.40.30.20 1 93 3.1E-28 T 05-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 K08M4_RS14920 0ad00c39d8b347992dac7bdc00e9b095 513 SUPERFAMILY SSF52540 96 381 8.13E-95 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14920 0ad00c39d8b347992dac7bdc00e9b095 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 2 512 1.0E-248 T 05-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 K08M4_RS14920 0ad00c39d8b347992dac7bdc00e9b095 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 92 4.4E-13 T 05-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS15990 11f54ae3586a08cade146961dd310472 249 Pfam PF00005 ABC transporter 19 174 2.0E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS15990 11f54ae3586a08cade146961dd310472 249 SUPERFAMILY SSF52540 5 235 8.52E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15990 11f54ae3586a08cade146961dd310472 249 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 4 249 7.3E-124 T 05-07-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 K08M4_RS15990 11f54ae3586a08cade146961dd310472 249 Gene3D G3DSA:3.40.50.300 5 244 2.6E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15990 11f54ae3586a08cade146961dd310472 249 SMART SM00382 28 220 2.7E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS15990 11f54ae3586a08cade146961dd310472 249 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS16665 8f5ed54cd3fbb94b6822d8e2e845ada4 104 SMART SM00465 8 87 0.0074 T 05-07-2017 IPR000305 GIY-YIG nuclease superfamily K08M4_RS16665 8f5ed54cd3fbb94b6822d8e2e845ada4 104 Pfam PF01541 GIY-YIG catalytic domain 10 81 5.9E-18 T 05-07-2017 IPR000305 GIY-YIG nuclease superfamily K08M4_RS16665 8f5ed54cd3fbb94b6822d8e2e845ada4 104 SUPERFAMILY SSF82771 10 80 9.81E-16 T 05-07-2017 IPR000305 GIY-YIG nuclease superfamily K08M4_RS12530 23037d34cdef0119ffde37193f821621 132 Pfam PF00293 NUDIX domain 5 125 5.7E-21 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 K08M4_RS12530 23037d34cdef0119ffde37193f821621 132 TIGRFAM TIGR00586 mutt: mutator mutT protein 1 127 4.7E-42 T 05-07-2017 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 K08M4_RS12530 23037d34cdef0119ffde37193f821621 132 SUPERFAMILY SSF55811 1 128 1.62E-34 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS12530 23037d34cdef0119ffde37193f821621 132 PRINTS PR00502 NUDIX hydrolase family signature 34 48 2.2E-9 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 K08M4_RS12530 23037d34cdef0119ffde37193f821621 132 PRINTS PR00502 NUDIX hydrolase family signature 48 63 2.2E-9 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 K08M4_RS12530 23037d34cdef0119ffde37193f821621 132 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 K08M4_RS12530 23037d34cdef0119ffde37193f821621 132 Gene3D G3DSA:3.90.79.10 1 128 9.2E-33 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS01525 80b8d3de9e6bc11f0c13fb00899fa0b0 179 PIRSF PIRSF002161 1 179 3.4E-67 T 05-07-2017 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01525 80b8d3de9e6bc11f0c13fb00899fa0b0 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 45.067 T 05-07-2017 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01525 80b8d3de9e6bc11f0c13fb00899fa0b0 179 Pfam PF00281 Ribosomal protein L5 24 80 2.1E-29 T 05-07-2017 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01525 80b8d3de9e6bc11f0c13fb00899fa0b0 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 2.8E-41 T 05-07-2017 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01525 80b8d3de9e6bc11f0c13fb00899fa0b0 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 05-07-2017 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01525 80b8d3de9e6bc11f0c13fb00899fa0b0 179 Gene3D G3DSA:3.30.1440.10 2 179 1.1E-79 T 05-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01525 80b8d3de9e6bc11f0c13fb00899fa0b0 179 SUPERFAMILY SSF55282 4 179 1.46E-78 T 05-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS04875 3449e3cbc03c793479ed27165b87b18c 846 Pfam PF10531 SLBB domain 296 345 8.4E-9 T 05-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS04875 3449e3cbc03c793479ed27165b87b18c 846 SUPERFAMILY SSF46548 337 445 1.83E-19 T 05-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 K08M4_RS04875 3449e3cbc03c793479ed27165b87b18c 846 Gene3D G3DSA:1.10.1060.10 364 450 9.7E-18 T 05-07-2017 K08M4_RS04875 3449e3cbc03c793479ed27165b87b18c 846 SUPERFAMILY SSF142019 95 302 2.09E-59 T 05-07-2017 K08M4_RS04875 3449e3cbc03c793479ed27165b87b18c 846 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 799 239.084 T 05-07-2017 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 K08M4_RS04875 3449e3cbc03c793479ed27165b87b18c 846 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 13 448 3.9E-185 T 05-07-2017 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 K08M4_RS04875 3449e3cbc03c793479ed27165b87b18c 846 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 140 283 1.9E-47 T 05-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS04875 3449e3cbc03c793479ed27165b87b18c 846 Pfam PF13375 RnfC Barrel sandwich hybrid domain 14 115 9.7E-34 T 05-07-2017 IPR026902 RnfC Barrel sandwich hybrid domain K08M4_RS04875 3449e3cbc03c793479ed27165b87b18c 846 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 417 428 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS04875 3449e3cbc03c793479ed27165b87b18c 846 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 378 389 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS04875 3449e3cbc03c793479ed27165b87b18c 846 Pfam PF12838 4Fe-4S dicluster domain 378 430 4.1E-7 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain K08M4_RS13720 b4770b6068ab88a4a890e741e10e8f1c 96 Pfam PF00166 Chaperonin 10 Kd subunit 2 95 5.5E-31 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 K08M4_RS13720 b4770b6068ab88a4a890e741e10e8f1c 96 Gene3D G3DSA:2.30.33.40 1 96 1.5E-32 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 K08M4_RS13720 b4770b6068ab88a4a890e741e10e8f1c 96 PRINTS PR00297 10kDa chaperonin signature 82 95 8.1E-27 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 K08M4_RS13720 b4770b6068ab88a4a890e741e10e8f1c 96 PRINTS PR00297 10kDa chaperonin signature 3 18 8.1E-27 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 K08M4_RS13720 b4770b6068ab88a4a890e741e10e8f1c 96 PRINTS PR00297 10kDa chaperonin signature 60 72 8.1E-27 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 K08M4_RS13720 b4770b6068ab88a4a890e741e10e8f1c 96 PRINTS PR00297 10kDa chaperonin signature 25 46 8.1E-27 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 K08M4_RS13720 b4770b6068ab88a4a890e741e10e8f1c 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 05-07-2017 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 K08M4_RS13720 b4770b6068ab88a4a890e741e10e8f1c 96 SMART SM00883 2 95 5.5E-50 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 K08M4_RS13720 b4770b6068ab88a4a890e741e10e8f1c 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 96 24.117 T 05-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 K08M4_RS13720 b4770b6068ab88a4a890e741e10e8f1c 96 SUPERFAMILY SSF50129 1 96 3.88E-31 T 05-07-2017 IPR011032 GroES-like K08M4_RS10360 6c07929e9e561a840e5c4b5c7b7487d1 182 TIGRFAM TIGR03902 rhom_GG_sort: rhombosortase 22 169 7.7E-49 T 05-07-2017 IPR023826 Rhomboid-like serine protease, proteobacteria K08M4_RS10360 6c07929e9e561a840e5c4b5c7b7487d1 182 Pfam PF01694 Rhomboid family 32 172 4.4E-12 T 05-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 K08M4_RS10360 6c07929e9e561a840e5c4b5c7b7487d1 182 SUPERFAMILY SSF144091 4 175 6.41E-27 T 05-07-2017 K08M4_RS10360 6c07929e9e561a840e5c4b5c7b7487d1 182 Gene3D G3DSA:1.20.1540.10 6 171 5.1E-17 T 05-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 K08M4_RS02735 bff206a60bd2e3ff1c054a75c3ac139b 423 Pfam PF03471 Transporter associated domain 344 417 9.1E-16 T 05-07-2017 IPR005170 Transporter-associated domain K08M4_RS02735 bff206a60bd2e3ff1c054a75c3ac139b 423 SMART SM01091 342 420 2.7E-21 T 05-07-2017 IPR005170 Transporter-associated domain K08M4_RS02735 bff206a60bd2e3ff1c054a75c3ac139b 423 Pfam PF01595 Domain of unknown function DUF21 13 181 2.0E-48 T 05-07-2017 IPR002550 Domain of unknown function DUF21 K08M4_RS02735 bff206a60bd2e3ff1c054a75c3ac139b 423 Pfam PF00571 CBS domain 279 326 0.001 T 05-07-2017 IPR000644 CBS domain K08M4_RS02735 bff206a60bd2e3ff1c054a75c3ac139b 423 Gene3D G3DSA:3.10.580.10 192 318 1.2E-12 T 05-07-2017 K08M4_RS02735 bff206a60bd2e3ff1c054a75c3ac139b 423 SUPERFAMILY SSF56176 339 418 1.55E-19 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 K08M4_RS02735 bff206a60bd2e3ff1c054a75c3ac139b 423 Gene3D G3DSA:3.30.465.10 319 417 2.4E-22 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 K08M4_RS02735 bff206a60bd2e3ff1c054a75c3ac139b 423 SUPERFAMILY SSF54631 192 329 3.79E-24 T 05-07-2017 K08M4_RS02920 aac52e4ddfe03457f5177fbc96a3630b 862 Pfam PF11791 Aconitate B N-terminal domain 4 156 1.9E-65 T 05-07-2017 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 K08M4_RS02920 aac52e4ddfe03457f5177fbc96a3630b 862 SUPERFAMILY SSF53732 377 857 2.09E-145 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS02920 aac52e4ddfe03457f5177fbc96a3630b 862 ProSitePatterns PS01244 Aconitase family signature 2. 758 771 - T 05-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 K08M4_RS02920 aac52e4ddfe03457f5177fbc96a3630b 862 Gene3D G3DSA:3.30.499.10 399 516 7.2E-63 T 05-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS02920 aac52e4ddfe03457f5177fbc96a3630b 862 Pfam PF00330 Aconitase family (aconitate hydratase) 469 815 7.8E-42 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS02920 aac52e4ddfe03457f5177fbc96a3630b 862 Gene3D G3DSA:3.20.19.10 163 358 1.2E-88 T 05-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel K08M4_RS02920 aac52e4ddfe03457f5177fbc96a3630b 862 SUPERFAMILY SSF74778 2 159 1.83E-66 T 05-07-2017 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 K08M4_RS02920 aac52e4ddfe03457f5177fbc96a3630b 862 SUPERFAMILY SSF52016 162 369 5.1E-67 T 05-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel K08M4_RS02920 aac52e4ddfe03457f5177fbc96a3630b 862 PIRSF PIRSF036687 1 856 0.0 T 05-07-2017 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 K08M4_RS02920 aac52e4ddfe03457f5177fbc96a3630b 862 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 851 0.0 T 05-07-2017 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 K08M4_RS02920 aac52e4ddfe03457f5177fbc96a3630b 862 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 379 3.8E-94 T 05-07-2017 IPR015929 Aconitase B, N-terminal GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 K08M4_RS02920 aac52e4ddfe03457f5177fbc96a3630b 862 Gene3D G3DSA:3.40.1060.10 517 679 8.7E-83 T 05-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS02920 aac52e4ddfe03457f5177fbc96a3630b 862 Gene3D G3DSA:3.30.499.10 681 856 1.2E-52 T 05-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS10675 b5b00eb90c5aa23178036019a52b2363 168 Hamap MF_00951 Transcription antitermination protein RfaH [rfaH]. 1 167 47.241 T 05-07-2017 IPR010215 Transcription antitermination protein RfaH GO:0006355 K08M4_RS10675 b5b00eb90c5aa23178036019a52b2363 168 SUPERFAMILY SSF82679 1 100 1.57E-29 T 05-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 K08M4_RS10675 b5b00eb90c5aa23178036019a52b2363 168 SUPERFAMILY SSF50104 113 164 3.61E-5 T 05-07-2017 IPR008991 Translation protein SH3-like domain K08M4_RS10675 b5b00eb90c5aa23178036019a52b2363 168 Gene3D G3DSA:3.30.70.940 1 97 5.6E-22 T 05-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 K08M4_RS10675 b5b00eb90c5aa23178036019a52b2363 168 Pfam PF02357 Transcription termination factor nusG 2 94 2.7E-21 T 05-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 K08M4_RS10675 b5b00eb90c5aa23178036019a52b2363 168 SMART SM00738 1 101 6.3E-28 T 05-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 K08M4_RS10675 b5b00eb90c5aa23178036019a52b2363 168 Gene3D G3DSA:2.30.30.30 113 160 3.4E-4 T 05-07-2017 IPR014722 Ribosomal protein L2 domain 2 K08M4_RS10675 b5b00eb90c5aa23178036019a52b2363 168 TIGRFAM TIGR01955 RfaH: transcription elongation factor/antiterminator RfaH 4 164 4.2E-61 T 05-07-2017 IPR010215 Transcription antitermination protein RfaH GO:0006355 K08M4_RS09355 a6bc88125a3359a005f3392f1c32add1 295 SUPERFAMILY SSF161098 89 276 1.44E-21 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS09355 a6bc88125a3359a005f3392f1c32add1 295 Gene3D G3DSA:1.10.3720.10 91 291 6.4E-20 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS09355 a6bc88125a3359a005f3392f1c32add1 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 293 8.0E-21 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS09355 a6bc88125a3359a005f3392f1c32add1 295 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 14 65 2.7E-13 T 05-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain K08M4_RS17780 dde171ee192a72784f048034efe0ed81 457 SMART SM00388 257 320 7.2E-8 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS17780 dde171ee192a72784f048034efe0ed81 457 SUPERFAMILY SSF55874 310 444 2.05E-13 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS17780 dde171ee192a72784f048034efe0ed81 457 Gene3D G3DSA:1.10.287.130 251 316 3.5E-8 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS17780 dde171ee192a72784f048034efe0ed81 457 SUPERFAMILY SSF47384 241 319 1.63E-9 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS17780 dde171ee192a72784f048034efe0ed81 457 Pfam PF00512 His Kinase A (phospho-acceptor) domain 261 319 5.6E-9 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS17780 dde171ee192a72784f048034efe0ed81 457 Gene3D G3DSA:3.30.565.10 329 406 4.3E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS07795 46fcfbe0648bc09cc5da1131df0bbc45 706 Gene3D G3DSA:3.40.50.150 255 334 5.3E-28 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS07795 46fcfbe0648bc09cc5da1131df0bbc45 706 Gene3D G3DSA:3.40.50.150 154 214 5.3E-28 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS07795 46fcfbe0648bc09cc5da1131df0bbc45 706 PIRSF PIRSF037618 1 706 7.3E-297 T 05-07-2017 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS07795 46fcfbe0648bc09cc5da1131df0bbc45 706 SUPERFAMILY SSF53335 399 705 1.32E-67 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS07795 46fcfbe0648bc09cc5da1131df0bbc45 706 SUPERFAMILY SSF53335 258 371 1.63E-40 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS07795 46fcfbe0648bc09cc5da1131df0bbc45 706 SUPERFAMILY SSF53335 139 217 1.63E-40 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS07795 46fcfbe0648bc09cc5da1131df0bbc45 706 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 305 311 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 K08M4_RS07795 46fcfbe0648bc09cc5da1131df0bbc45 706 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 195 206 - T 05-07-2017 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS07795 46fcfbe0648bc09cc5da1131df0bbc45 706 Hamap MF_01858 Ribosomal RNA large subunit methyltransferase K/L [rlmL]. 4 706 31.653 T 05-07-2017 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS07795 46fcfbe0648bc09cc5da1131df0bbc45 706 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 434 662 1.8E-28 T 05-07-2017 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 K08M4_RS07795 46fcfbe0648bc09cc5da1131df0bbc45 706 Pfam PF02926 THUMP domain 31 153 1.6E-12 T 05-07-2017 IPR004114 THUMP domain GO:0003723 K08M4_RS07795 46fcfbe0648bc09cc5da1131df0bbc45 706 Gene3D G3DSA:3.40.50.150 436 705 2.7E-75 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS07795 46fcfbe0648bc09cc5da1131df0bbc45 706 SMART SM00981 56 154 3.0E-19 T 05-07-2017 IPR004114 THUMP domain GO:0003723 K08M4_RS07795 46fcfbe0648bc09cc5da1131df0bbc45 706 Pfam PF01170 Putative RNA methylase family UPF0020 162 374 6.7E-63 T 05-07-2017 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 Gene3D G3DSA:1.10.10.650 1 109 1.3E-46 T 05-07-2017 IPR023319 Tex-like protein, HTH domain K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 SUPERFAMILY SSF53098 322 469 1.44E-49 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 SUPERFAMILY SSF158832 3 321 1.23E-117 T 05-07-2017 K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 Pfam PF16921 Tex protein YqgF-like domain 327 451 3.5E-55 T 05-07-2017 IPR032639 Tex protein, YqgF-like domain K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 Pfam PF09371 Tex-like protein N-terminal domain 9 192 3.9E-70 T 05-07-2017 IPR018974 Tex-like protein, N-terminal K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 SUPERFAMILY SSF47781 470 557 1.45E-26 T 05-07-2017 IPR010994 RuvA domain 2-like K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 SUPERFAMILY SSF47781 560 632 7.56E-19 T 05-07-2017 IPR010994 RuvA domain 2-like K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 Gene3D G3DSA:1.10.150.310 499 630 1.3E-45 T 05-07-2017 IPR023097 Tex RuvX-like domain K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 SUPERFAMILY SSF50249 637 723 7.09E-25 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 Gene3D G3DSA:3.30.420.140 327 450 5.3E-52 T 05-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 Gene3D G3DSA:1.10.3500.10 110 322 9.1E-100 T 05-07-2017 IPR023323 Tex-like domain K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 Gene3D G3DSA:1.10.3500.10 451 498 9.1E-100 T 05-07-2017 IPR023323 Tex-like domain K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 SMART SM00732 326 424 9.2E-35 T 05-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 Gene3D G3DSA:2.40.50.140 633 721 6.6E-29 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 Pfam PF12836 Helix-hairpin-helix motif 491 555 3.3E-27 T 05-07-2017 K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 Pfam PF00575 S1 RNA binding domain 649 720 2.1E-21 T 05-07-2017 IPR003029 S1 domain GO:0003676 K08M4_RS14160 c8f0a899052569810765e776346c17a2 776 SMART SM00316 649 720 1.9E-25 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS15340 2470002e78e0e55554ca05beb1795ba4 322 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 264 277 - T 05-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 K08M4_RS15340 2470002e78e0e55554ca05beb1795ba4 322 Gene3D G3DSA:3.40.1190.20 1 309 3.4E-70 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS15340 2470002e78e0e55554ca05beb1795ba4 322 Pfam PF00294 pfkB family carbohydrate kinase 1 309 1.4E-64 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB K08M4_RS15340 2470002e78e0e55554ca05beb1795ba4 322 SUPERFAMILY SSF53613 1 310 1.56E-68 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS10185 fb9dd5b171fedb1efd648389edf92814 277 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 243 258 5.0E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS10185 fb9dd5b171fedb1efd648389edf92814 277 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 258 274 5.0E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS10185 fb9dd5b171fedb1efd648389edf92814 277 SUPERFAMILY SSF46689 176 226 6.27E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS10185 fb9dd5b171fedb1efd648389edf92814 277 Gene3D G3DSA:1.10.10.60 231 273 2.4E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS10185 fb9dd5b171fedb1efd648389edf92814 277 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 229 270 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 K08M4_RS10185 fb9dd5b171fedb1efd648389edf92814 277 Gene3D G3DSA:1.10.10.60 173 230 5.4E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS10185 fb9dd5b171fedb1efd648389edf92814 277 Pfam PF12833 Helix-turn-helix domain 199 275 4.7E-20 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS10185 fb9dd5b171fedb1efd648389edf92814 277 SMART SM00342 192 274 3.5E-27 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS10185 fb9dd5b171fedb1efd648389edf92814 277 SUPERFAMILY SSF51215 33 158 9.55E-20 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 K08M4_RS10185 fb9dd5b171fedb1efd648389edf92814 277 Gene3D G3DSA:2.60.120.280 31 155 1.3E-11 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 K08M4_RS10185 fb9dd5b171fedb1efd648389edf92814 277 SUPERFAMILY SSF46689 229 275 1.16E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS10185 fb9dd5b171fedb1efd648389edf92814 277 Pfam PF02311 AraC-like ligand binding domain 21 152 1.5E-26 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 K08M4_RS03810 9c70687756d3e1986288ff698b7707c3 362 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 359 40.16 T 05-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 K08M4_RS03810 9c70687756d3e1986288ff698b7707c3 362 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 230 246 - T 05-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 K08M4_RS03810 9c70687756d3e1986288ff698b7707c3 362 Gene3D G3DSA:1.20.58.410 7 94 3.7E-25 T 05-07-2017 K08M4_RS03810 9c70687756d3e1986288ff698b7707c3 362 SMART SM00937 67 180 4.9E-65 T 05-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 K08M4_RS03810 9c70687756d3e1986288ff698b7707c3 362 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 359 1.6E-169 T 05-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 K08M4_RS03810 9c70687756d3e1986288ff698b7707c3 362 Gene3D G3DSA:3.30.160.20 217 289 6.3E-35 T 05-07-2017 IPR014720 Double-stranded RNA-binding domain K08M4_RS03810 9c70687756d3e1986288ff698b7707c3 362 Pfam PF03462 PCRF domain 13 205 2.6E-75 T 05-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 K08M4_RS03810 9c70687756d3e1986288ff698b7707c3 362 SUPERFAMILY SSF75620 12 355 1.83E-135 T 05-07-2017 K08M4_RS03810 9c70687756d3e1986288ff698b7707c3 362 Pfam PF00472 RF-1 domain 218 323 3.5E-40 T 05-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 K08M4_RS11970 29950ed051c300453ce62e79aed8d011 646 Gene3D G3DSA:1.10.287.950 401 616 7.6E-54 T 05-07-2017 K08M4_RS11970 29950ed051c300453ce62e79aed8d011 646 SMART SM01358 33 286 1.0E-45 T 05-07-2017 IPR032255 Helical bimodular sensor domain K08M4_RS11970 29950ed051c300453ce62e79aed8d011 646 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 450 643 1.3E-46 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS11970 29950ed051c300453ce62e79aed8d011 646 SMART SM00283 384 645 9.4E-69 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS11970 29950ed051c300453ce62e79aed8d011 646 SUPERFAMILY SSF58104 360 646 2.49E-69 T 05-07-2017 K08M4_RS11970 29950ed051c300453ce62e79aed8d011 646 Pfam PF12729 Four helix bundle sensory module for signal transduction 2 150 7.9E-8 T 05-07-2017 IPR024478 4HB MCP domain K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 616 45.592 T 05-07-2017 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 SUPERFAMILY SSF100920 383 536 2.09E-50 T 05-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 Gene3D G3DSA:3.90.640.10 239 309 7.8E-6 T 05-07-2017 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 615 2.0E-266 T 05-07-2017 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 05-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 Pfam PF00012 Hsp70 protein 21 600 7.6E-192 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 SUPERFAMILY SSF100934 503 615 3.73E-33 T 05-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 PRINTS PR00301 70kDa heat shock protein signature 359 379 1.5E-53 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 PRINTS PR00301 70kDa heat shock protein signature 20 33 1.5E-53 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 PRINTS PR00301 70kDa heat shock protein signature 152 172 1.5E-53 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 PRINTS PR00301 70kDa heat shock protein signature 465 481 1.5E-53 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 PRINTS PR00301 70kDa heat shock protein signature 211 221 1.5E-53 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 PRINTS PR00301 70kDa heat shock protein signature 328 344 1.5E-53 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 PRINTS PR00301 70kDa heat shock protein signature 384 403 1.5E-53 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 PRINTS PR00301 70kDa heat shock protein signature 48 60 1.5E-53 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 SUPERFAMILY SSF53067 200 376 1.58E-48 T 05-07-2017 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 Gene3D G3DSA:3.30.420.40 206 238 4.4E-31 T 05-07-2017 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 Gene3D G3DSA:3.30.420.40 313 355 4.4E-31 T 05-07-2017 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 Gene3D G3DSA:2.60.34.10 386 527 1.3E-53 T 05-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 Gene3D G3DSA:3.30.420.40 133 205 8.2E-54 T 05-07-2017 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 Gene3D G3DSA:3.30.420.40 20 69 8.2E-54 T 05-07-2017 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 SUPERFAMILY SSF53067 19 196 1.61E-52 T 05-07-2017 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 Gene3D G3DSA:1.20.1270.10 528 615 1.0E-28 T 05-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 205 218 - T 05-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 K08M4_RS11880 463f183dadc15f7fadd792a89f7f32a7 616 Gene3D G3DSA:3.30.30.30 70 122 4.7E-11 T 05-07-2017 K08M4_RS01330 2011efb87262eb5f5093d516853955c1 403 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 16 399 3.1E-150 T 05-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 K08M4_RS01330 2011efb87262eb5f5093d516853955c1 403 SUPERFAMILY SSF53383 15 399 5.24E-127 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS01330 2011efb87262eb5f5093d516853955c1 403 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 13 400 45.479 T 05-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 K08M4_RS01330 2011efb87262eb5f5093d516853955c1 403 TIGRFAM TIGR03246 arg_catab_astC: succinylornithine transaminase family 7 403 2.9E-208 T 05-07-2017 IPR017652 Acetyl/Succinylornithine transaminase family, bacteria GO:0006520|GO:0008483|GO:0030170 K08M4_RS01330 2011efb87262eb5f5093d516853955c1 403 Pfam PF00202 Aminotransferase class-III 22 399 1.9E-127 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 K08M4_RS01330 2011efb87262eb5f5093d516853955c1 403 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 222 259 - T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 K08M4_RS01330 2011efb87262eb5f5093d516853955c1 403 Gene3D G3DSA:3.40.640.10 60 302 3.0E-90 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS01330 2011efb87262eb5f5093d516853955c1 403 Gene3D G3DSA:3.90.1150.10 306 400 3.0E-36 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS01330 2011efb87262eb5f5093d516853955c1 403 Gene3D G3DSA:3.90.1150.10 13 59 3.0E-36 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS00595 d94f0906f86cfe4969781874f69f8351 284 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 8 283 7.4E-106 T 05-07-2017 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 K08M4_RS00595 d94f0906f86cfe4969781874f69f8351 284 Pfam PF01040 UbiA prenyltransferase family 24 266 6.7E-69 T 05-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 K08M4_RS00595 d94f0906f86cfe4969781874f69f8351 284 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 1 284 29.5 T 05-07-2017 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 K08M4_RS00410 cb4430e70c09f334fcacd76205672c1f 104 SUPERFAMILY SSF55387 1 103 5.76E-38 T 05-07-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 K08M4_RS00410 cb4430e70c09f334fcacd76205672c1f 104 Hamap MF_00142 Protein CyaY [cyaY]. 1 103 26.889 T 05-07-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 K08M4_RS00410 cb4430e70c09f334fcacd76205672c1f 104 ProSitePatterns PS01344 Frataxin family signature. 48 62 - T 05-07-2017 IPR020895 Frataxin conserved site Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 K08M4_RS00410 cb4430e70c09f334fcacd76205672c1f 104 SMART SM01219 1 104 7.9E-52 T 05-07-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 K08M4_RS00410 cb4430e70c09f334fcacd76205672c1f 104 Pfam PF01491 Frataxin-like domain 1 100 9.1E-30 T 05-07-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 K08M4_RS00410 cb4430e70c09f334fcacd76205672c1f 104 Gene3D G3DSA:3.30.920.10 1 103 5.3E-34 T 05-07-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 K08M4_RS00410 cb4430e70c09f334fcacd76205672c1f 104 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 2 103 3.2E-41 T 05-07-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 K08M4_RS17185 618951c4fb12811dfb28b5f8ad945941 918 Pfam PF00801 PKD domain 780 826 8.2E-10 T 05-07-2017 IPR000601 PKD domain K08M4_RS17185 618951c4fb12811dfb28b5f8ad945941 918 Pfam PF00801 PKD domain 844 910 1.2E-8 T 05-07-2017 IPR000601 PKD domain K08M4_RS17185 618951c4fb12811dfb28b5f8ad945941 918 SUPERFAMILY SSF49299 756 838 4.45E-20 T 05-07-2017 IPR000601 PKD domain K08M4_RS17185 618951c4fb12811dfb28b5f8ad945941 918 SUPERFAMILY SSF49299 838 916 6.28E-10 T 05-07-2017 IPR000601 PKD domain K08M4_RS17185 618951c4fb12811dfb28b5f8ad945941 918 PIRSF PIRSF007519 1 758 0.0 T 05-07-2017 IPR012300 Peptidase M6, InhA K08M4_RS17185 618951c4fb12811dfb28b5f8ad945941 918 Pfam PF05547 Immune inhibitor A peptidase M6 105 747 2.2E-274 T 05-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 K08M4_RS17185 618951c4fb12811dfb28b5f8ad945941 918 Gene3D G3DSA:3.40.390.10 228 251 3.4E-22 T 05-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 K08M4_RS17185 618951c4fb12811dfb28b5f8ad945941 918 Gene3D G3DSA:3.40.390.10 310 378 3.4E-22 T 05-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 K08M4_RS17185 618951c4fb12811dfb28b5f8ad945941 918 SMART SM00089 841 917 1.3E-9 T 05-07-2017 IPR022409 PKD/Chitinase domain K08M4_RS17185 618951c4fb12811dfb28b5f8ad945941 918 SMART SM00089 760 838 6.8E-17 T 05-07-2017 IPR022409 PKD/Chitinase domain K08M4_RS17185 618951c4fb12811dfb28b5f8ad945941 918 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 141 443 3.5E-81 T 05-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 K08M4_RS17185 618951c4fb12811dfb28b5f8ad945941 918 SUPERFAMILY SSF55486 211 260 1.44E-19 T 05-07-2017 K08M4_RS17185 618951c4fb12811dfb28b5f8ad945941 918 SUPERFAMILY SSF55486 310 385 1.44E-19 T 05-07-2017 K08M4_RS17185 618951c4fb12811dfb28b5f8ad945941 918 Gene3D G3DSA:2.60.40.670 758 840 6.4E-20 T 05-07-2017 IPR000601 PKD domain K08M4_RS17185 618951c4fb12811dfb28b5f8ad945941 918 Gene3D G3DSA:2.60.40.670 848 916 8.6E-6 T 05-07-2017 IPR000601 PKD domain K08M4_RS12820 8962dbe716c915639c08fade83ea80e8 71 Pfam PF01165 Ribosomal protein S21 4 56 4.7E-23 T 05-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS12820 8962dbe716c915639c08fade83ea80e8 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 4.9E-25 T 05-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS12820 8962dbe716c915639c08fade83ea80e8 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 44 2.0E-10 T 05-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS12820 8962dbe716c915639c08fade83ea80e8 71 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 05-07-2017 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS12820 8962dbe716c915639c08fade83ea80e8 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.6E-16 T 05-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS12820 8962dbe716c915639c08fade83ea80e8 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.6E-16 T 05-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS12820 8962dbe716c915639c08fade83ea80e8 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.6E-16 T 05-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS12820 8962dbe716c915639c08fade83ea80e8 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.6E-16 T 05-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS12820 8962dbe716c915639c08fade83ea80e8 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.344 T 05-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS03605 2045e95b1b95f1d69e393c753ae2f799 279 Pfam PF03330 Lytic transglycolase 96 185 7.6E-27 T 05-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain K08M4_RS03605 2045e95b1b95f1d69e393c753ae2f799 279 Gene3D G3DSA:2.40.40.10 135 187 2.7E-5 T 05-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain K08M4_RS03605 2045e95b1b95f1d69e393c753ae2f799 279 Pfam PF05036 Sporulation related domain 204 272 5.7E-6 T 05-07-2017 IPR007730 Sporulation-related domain GO:0042834 K08M4_RS03605 2045e95b1b95f1d69e393c753ae2f799 279 SUPERFAMILY SSF50685 100 186 6.8E-10 T 05-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain K08M4_RS03605 2045e95b1b95f1d69e393c753ae2f799 279 SUPERFAMILY SSF110997 204 273 1.7E-8 T 05-07-2017 IPR007730 Sporulation-related domain GO:0042834 K08M4_RS03605 2045e95b1b95f1d69e393c753ae2f799 279 Gene3D G3DSA:3.30.70.1070 200 273 1.1E-4 T 05-07-2017 IPR007730 Sporulation-related domain GO:0042834 K08M4_RS03605 2045e95b1b95f1d69e393c753ae2f799 279 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 98 192 2.1E-44 T 05-07-2017 IPR012997 Rare lipoprotein A K08M4_RS09715 3eced0f996f05a310f5f7033f839326c 449 Gene3D G3DSA:1.20.272.10 250 348 2.8E-43 T 05-07-2017 K08M4_RS09715 3eced0f996f05a310f5f7033f839326c 449 SUPERFAMILY SSF48019 253 435 1.87E-72 T 05-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 K08M4_RS09715 3eced0f996f05a310f5f7033f839326c 449 Pfam PF16193 AAA C-terminal domain 192 268 2.9E-19 T 05-07-2017 IPR032423 AAA ATPase, C-terminal domain K08M4_RS09715 3eced0f996f05a310f5f7033f839326c 449 Gene3D G3DSA:1.10.8.60 155 243 4.1E-7 T 05-07-2017 K08M4_RS09715 3eced0f996f05a310f5f7033f839326c 449 Pfam PF12002 MgsA AAA+ ATPase C terminal 269 435 5.2E-67 T 05-07-2017 IPR021886 MgsA AAA+ ATPase C-terminal K08M4_RS09715 3eced0f996f05a310f5f7033f839326c 449 SMART SM00382 50 166 2.6E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS09715 3eced0f996f05a310f5f7033f839326c 449 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 54 159 2.0E-16 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 K08M4_RS09715 3eced0f996f05a310f5f7033f839326c 449 Gene3D G3DSA:3.40.50.300 13 154 3.6E-33 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09715 3eced0f996f05a310f5f7033f839326c 449 SUPERFAMILY SSF52540 10 235 3.54E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09715 3eced0f996f05a310f5f7033f839326c 449 Gene3D G3DSA:1.10.3710.10 349 447 9.1E-33 T 05-07-2017 K08M4_RS05990 00563a6325d2c0b79b4772c0265d5baa 135 Pfam PF03846 Cell division inhibitor SulA 34 101 3.7E-7 T 05-07-2017 IPR004596 Cell division suppressor protein, SulA GO:0009276|GO:0009432|GO:0051782 K08M4_RS05990 00563a6325d2c0b79b4772c0265d5baa 135 Gene3D G3DSA:3.40.50.300 25 116 1.5E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05990 00563a6325d2c0b79b4772c0265d5baa 135 SUPERFAMILY SSF52540 28 116 2.5E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 179 468 1.8E-124 T 05-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 SUPERFAMILY SSF51735 4 174 3.67E-56 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 Gene3D G3DSA:1.20.5.320 435 481 3.4E-26 T 05-07-2017 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 249 276 6.5E-85 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 168 196 6.5E-85 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 6.5E-85 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 3 26 6.5E-85 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 356 378 6.5E-85 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 6.5E-85 T 05-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 SUPERFAMILY SSF48179 177 472 1.08E-126 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 PIRSF PIRSF000109 1 477 9.6E-242 T 05-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 Gene3D G3DSA:3.40.50.720 2 180 9.4E-59 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 169 2.8E-51 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 SMART SM01350 179 469 1.7E-214 T 05-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 253 265 - T 05-07-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 4 469 5.0E-234 T 05-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 K08M4_RS08075 df546bc62b75d4369e840b1262d85a3f 482 Gene3D G3DSA:1.10.1040.10 181 433 8.6E-114 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 K08M4_RS06425 b83b5ffe0539a1b4041bbe2f628c0409 297 SUPERFAMILY SSF53850 90 294 1.71E-44 T 05-07-2017 K08M4_RS06425 b83b5ffe0539a1b4041bbe2f628c0409 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.2E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS06425 b83b5ffe0539a1b4041bbe2f628c0409 297 Gene3D G3DSA:3.40.190.10 92 177 5.1E-23 T 05-07-2017 K08M4_RS06425 b83b5ffe0539a1b4041bbe2f628c0409 297 SUPERFAMILY SSF46785 3 111 4.17E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06425 b83b5ffe0539a1b4041bbe2f628c0409 297 Gene3D G3DSA:1.10.10.10 3 78 4.8E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06425 b83b5ffe0539a1b4041bbe2f628c0409 297 Pfam PF03466 LysR substrate binding domain 88 290 2.2E-40 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS06425 b83b5ffe0539a1b4041bbe2f628c0409 297 Gene3D G3DSA:3.40.190.10 178 259 6.9E-6 T 05-07-2017 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 SUPERFAMILY SSF82693 136 181 1.4E-20 T 05-07-2017 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 SUPERFAMILY SSF82693 267 323 1.4E-20 T 05-07-2017 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 Gene3D G3DSA:1.20.1640.10 284 500 5.5E-54 T 05-07-2017 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 Gene3D G3DSA:3.30.70.1430 41 141 8.2E-28 T 05-07-2017 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 Pfam PF00873 AcrB/AcrD/AcrF family 4 1003 3.4E-274 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 SUPERFAMILY SSF82714 182 263 1.44E-17 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 SUPERFAMILY SSF82714 701 783 5.36E-18 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 Gene3D G3DSA:3.30.2090.10 181 264 9.4E-20 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 SUPERFAMILY SSF82866 290 489 2.62E-46 T 05-07-2017 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 Gene3D G3DSA:3.30.70.1430 555 650 1.4E-14 T 05-07-2017 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 SUPERFAMILY SSF82693 553 650 5.23E-20 T 05-07-2017 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.4E-74 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 2.4E-74 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 2.4E-74 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 2.4E-74 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 2.4E-74 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 PRINTS PR00702 Acriflavin resistance protein family signature 603 617 2.4E-74 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 2.4E-74 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 2.4E-74 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.4E-74 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 SUPERFAMILY SSF82693 41 130 6.63E-23 T 05-07-2017 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 Gene3D G3DSA:1.10.3850.10 792 1006 2.3E-58 T 05-07-2017 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 SUPERFAMILY SSF82866 782 1008 2.35E-47 T 05-07-2017 K08M4_RS14660 593159519523b4ed6c6e2dade6505f2e 1040 Gene3D G3DSA:3.30.2090.10 700 787 8.0E-20 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS18010 568976c691d13c59bbf441a34fc51365 892 Gene3D G3DSA:3.40.228.10 205 421 4.7E-40 T 05-07-2017 K08M4_RS18010 568976c691d13c59bbf441a34fc51365 892 SUPERFAMILY SSF50692 722 785 3.14E-22 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain K08M4_RS18010 568976c691d13c59bbf441a34fc51365 892 SUPERFAMILY SSF50692 817 874 3.14E-22 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain K08M4_RS18010 568976c691d13c59bbf441a34fc51365 892 Gene3D G3DSA:2.40.40.20 724 785 8.9E-36 T 05-07-2017 K08M4_RS18010 568976c691d13c59bbf441a34fc51365 892 Gene3D G3DSA:2.40.40.20 817 878 8.9E-36 T 05-07-2017 K08M4_RS18010 568976c691d13c59bbf441a34fc51365 892 Gene3D G3DSA:3.40.50.740 696 705 1.1E-47 T 05-07-2017 K08M4_RS18010 568976c691d13c59bbf441a34fc51365 892 Gene3D G3DSA:3.40.50.740 118 194 1.1E-47 T 05-07-2017 K08M4_RS18010 568976c691d13c59bbf441a34fc51365 892 Gene3D G3DSA:3.40.50.740 422 634 1.1E-47 T 05-07-2017 K08M4_RS18010 568976c691d13c59bbf441a34fc51365 892 SUPERFAMILY SSF53706 8 308 1.96E-92 T 05-07-2017 K08M4_RS18010 568976c691d13c59bbf441a34fc51365 892 SUPERFAMILY SSF53706 339 668 1.96E-92 T 05-07-2017 K08M4_RS18010 568976c691d13c59bbf441a34fc51365 892 Pfam PF00384 Molybdopterin oxidoreductase 118 590 4.0E-36 T 05-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS18010 568976c691d13c59bbf441a34fc51365 892 Pfam PF01568 Molydopterin dinucleotide binding domain 728 785 1.7E-9 T 05-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 K08M4_RS05335 c1cfa6d78a494539aa139745c60c58b6 691 Pfam PF13307 Helicase C-terminal domain 526 684 1.7E-35 T 05-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 K08M4_RS05335 c1cfa6d78a494539aa139745c60c58b6 691 SMART SM00491 535 671 1.6E-28 T 05-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 K08M4_RS05335 c1cfa6d78a494539aa139745c60c58b6 691 Gene3D G3DSA:3.40.50.300 508 667 2.1E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05335 c1cfa6d78a494539aa139745c60c58b6 691 Gene3D G3DSA:3.40.50.300 212 280 1.3E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05335 c1cfa6d78a494539aa139745c60c58b6 691 Gene3D G3DSA:3.40.50.300 35 131 1.3E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05335 c1cfa6d78a494539aa139745c60c58b6 691 SUPERFAMILY SSF52540 195 268 3.55E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05335 c1cfa6d78a494539aa139745c60c58b6 691 SUPERFAMILY SSF52540 46 99 3.55E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05335 c1cfa6d78a494539aa139745c60c58b6 691 SUPERFAMILY SSF52540 445 459 3.55E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05335 c1cfa6d78a494539aa139745c60c58b6 691 SUPERFAMILY SSF52540 491 665 3.55E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05335 c1cfa6d78a494539aa139745c60c58b6 691 Pfam PF06733 DEAD_2 194 261 4.4E-6 T 05-07-2017 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 SUPERFAMILY SSF52172 2 187 3.13E-43 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 SMART SM00382 162 309 1.1E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 Pfam PF02954 Bacterial regulatory protein, Fis family 426 466 5.9E-16 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 Gene3D G3DSA:3.40.50.300 140 314 1.5E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 SUPERFAMILY SSF52540 141 385 8.69E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 Pfam PF00072 Response regulator receiver domain 6 115 1.8E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 05-07-2017 IPR025944 Sigma-54 interaction domain, conserved site K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 Gene3D G3DSA:1.10.10.60 400 466 2.2E-20 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 Pfam PF00158 Sigma-54 interaction domain 142 309 1.4E-70 T 05-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 Gene3D G3DSA:3.40.50.2300 6 139 5.0E-36 T 05-07-2017 K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 Gene3D G3DSA:1.10.8.60 315 391 4.3E-22 T 05-07-2017 K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 6 466 1.1E-239 T 05-07-2017 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 432 449 4.4E-7 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 449 467 4.4E-7 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 05-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 SMART SM00448 4 115 9.1E-33 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 SUPERFAMILY SSF46689 382 466 1.9E-20 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS14325 292e05669acba8a7f14ea4b84ab27cb6 467 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 05-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 K08M4_RS17105 c380358ed0485d0641ac0247849ef8bd 397 SUPERFAMILY SSF53383 4 394 2.55E-119 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS17105 c380358ed0485d0641ac0247849ef8bd 397 Gene3D G3DSA:3.90.1150.10 279 393 3.5E-34 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS17105 c380358ed0485d0641ac0247849ef8bd 397 Gene3D G3DSA:3.40.640.10 61 278 6.7E-87 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS17105 c380358ed0485d0641ac0247849ef8bd 397 Pfam PF00155 Aminotransferase class I and II 43 387 1.3E-72 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS17105 c380358ed0485d0641ac0247849ef8bd 397 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 5 397 1.6E-208 T 05-07-2017 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 K08M4_RS17105 c380358ed0485d0641ac0247849ef8bd 397 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 05-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 K08M4_RS17105 c380358ed0485d0641ac0247849ef8bd 397 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 395 53.423 T 05-07-2017 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 K08M4_RS01955 a72c7c36162a1d249f278ef2bf5bc0e3 158 Pfam PF06271 RDD family 9 148 7.1E-23 T 05-07-2017 IPR010432 RDD K08M4_RS02250 50cc304d3e011b307569b2d00fbfcc52 432 PIRSF PIRSF036428 14 428 1.5E-102 T 05-07-2017 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 K08M4_RS02250 50cc304d3e011b307569b2d00fbfcc52 432 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 18 211 1.2E-24 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS02250 50cc304d3e011b307569b2d00fbfcc52 432 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 256 377 7.8E-36 T 05-07-2017 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 K08M4_RS02250 50cc304d3e011b307569b2d00fbfcc52 432 Gene3D G3DSA:3.30.950.10 122 227 1.4E-21 T 05-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS02250 50cc304d3e011b307569b2d00fbfcc52 432 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 264 372 5.9E-5 T 05-07-2017 K08M4_RS02250 50cc304d3e011b307569b2d00fbfcc52 432 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 20 223 2.8E-50 T 05-07-2017 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 K08M4_RS02250 50cc304d3e011b307569b2d00fbfcc52 432 Gene3D G3DSA:3.40.1010.10 16 121 1.4E-18 T 05-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS02250 50cc304d3e011b307569b2d00fbfcc52 432 SUPERFAMILY SSF53790 18 225 1.7E-36 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS02250 50cc304d3e011b307569b2d00fbfcc52 432 Gene3D G3DSA:3.40.50.150 244 427 1.7E-23 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS02250 50cc304d3e011b307569b2d00fbfcc52 432 SUPERFAMILY SSF53335 242 392 5.97E-28 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS14355 1f30773e492991d15c0ae851166c20dd 205 SUPERFAMILY SSF46626 6 105 3.58E-21 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS14355 1f30773e492991d15c0ae851166c20dd 205 Gene3D G3DSA:1.10.760.10 132 203 1.8E-30 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS14355 1f30773e492991d15c0ae851166c20dd 205 Gene3D G3DSA:1.10.760.10 29 131 1.6E-28 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS14355 1f30773e492991d15c0ae851166c20dd 205 PIRSF PIRSF000005 1 205 1.1E-63 T 05-07-2017 IPR024167 Cytochrome c4 GO:0005506|GO:0009055|GO:0020037|GO:0042597 K08M4_RS14355 1f30773e492991d15c0ae851166c20dd 205 SUPERFAMILY SSF46626 115 203 8.72E-20 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS14355 1f30773e492991d15c0ae851166c20dd 205 Pfam PF00034 Cytochrome c 117 201 2.4E-9 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS14355 1f30773e492991d15c0ae851166c20dd 205 Pfam PF00034 Cytochrome c 25 103 2.5E-10 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS15920 889189b477f951d666ede2d3c985a4bb 526 SUPERFAMILY SSF48452 70 257 1.17E-12 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS15920 889189b477f951d666ede2d3c985a4bb 526 Pfam PF00990 Diguanylate cyclase, GGDEF domain 370 522 4.0E-34 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS15920 889189b477f951d666ede2d3c985a4bb 526 SUPERFAMILY SSF55073 374 524 5.65E-37 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS15920 889189b477f951d666ede2d3c985a4bb 526 SMART SM00267 358 526 5.9E-34 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS15920 889189b477f951d666ede2d3c985a4bb 526 Gene3D G3DSA:1.25.40.10 204 318 3.4E-15 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS15920 889189b477f951d666ede2d3c985a4bb 526 Gene3D G3DSA:1.25.40.10 32 163 3.4E-15 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS15920 889189b477f951d666ede2d3c985a4bb 526 Gene3D G3DSA:3.30.70.270 371 524 3.5E-41 T 05-07-2017 K08M4_RS15920 889189b477f951d666ede2d3c985a4bb 526 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 366 524 2.5E-34 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS11040 f1e3a236613d2dcab64ddd9d12341580 197 Gene3D G3DSA:3.40.50.360 2 194 3.5E-67 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS11040 f1e3a236613d2dcab64ddd9d12341580 197 Pfam PF03358 NADPH-dependent FMN reductase 7 141 3.6E-13 T 05-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 K08M4_RS11040 f1e3a236613d2dcab64ddd9d12341580 197 SUPERFAMILY SSF52218 4 190 5.11E-57 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS11040 f1e3a236613d2dcab64ddd9d12341580 197 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 4 189 1.4E-41 T 05-07-2017 IPR010089 Flavoprotein WrbA GO:0010181|GO:0045892 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 K08M4_RS11040 f1e3a236613d2dcab64ddd9d12341580 197 ProSitePatterns PS00201 Flavodoxin signature. 7 23 - T 05-07-2017 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 ProSitePatterns PS00110 Pyruvate kinase active site signature. 218 230 - T 05-07-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 SUPERFAMILY SSF52935 329 481 1.44E-35 T 05-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 Gene3D G3DSA:3.40.1380.20 332 478 3.3E-37 T 05-07-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 PRINTS PR01050 Pyruvate kinase family signature 190 204 5.8E-55 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 PRINTS PR01050 Pyruvate kinase family signature 223 249 5.8E-55 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 PRINTS PR01050 Pyruvate kinase family signature 250 274 5.8E-55 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 PRINTS PR01050 Pyruvate kinase family signature 275 299 5.8E-55 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 PRINTS PR01050 Pyruvate kinase family signature 63 79 5.8E-55 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 PRINTS PR01050 Pyruvate kinase family signature 300 318 5.8E-55 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 PRINTS PR01050 Pyruvate kinase family signature 319 335 5.8E-55 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 Gene3D G3DSA:2.40.33.10 77 170 1.6E-26 T 05-07-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 SUPERFAMILY SSF50800 74 169 1.31E-24 T 05-07-2017 IPR011037 Pyruvate kinase-like, insert domain K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 Pfam PF02887 Pyruvate kinase, alpha/beta domain 364 479 5.0E-28 T 05-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 Gene3D G3DSA:3.20.20.60 6 76 7.7E-93 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 Gene3D G3DSA:3.20.20.60 172 331 7.7E-93 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 SUPERFAMILY SSF51621 5 79 2.65E-86 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 SUPERFAMILY SSF51621 171 344 2.65E-86 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 Pfam PF00224 Pyruvate kinase, barrel domain 6 345 1.8E-127 T 05-07-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS05190 33c7bd67eac64aea6b11ad45be65dcc3 482 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 480 5.3E-163 T 05-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 4134 4253 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 1120 1239 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 5778 5897 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 1805 1924 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 4819 4938 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 3175 3294 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 7104 7122 - T 05-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 5093 5212 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 1531 1650 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 7095 7113 - T 05-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 3049 3070 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 4008 4029 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 994 1015 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 2090 2111 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 5104 5125 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 1953 1974 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 4967 4988 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 2912 2933 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 3186 3207 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 1131 1152 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 857 878 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 1268 1289 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 5789 5810 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 4282 4303 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 5241 5262 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 5378 5399 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 2364 2385 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 4830 4851 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 1816 1837 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 5926 5947 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 4693 4714 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 4145 4166 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 3597 3618 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 720 741 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 4556 4577 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 1542 1563 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 2501 2522 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 5515 5536 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 1405 1426 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 2638 2659 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 3734 3755 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 3460 3481 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 2775 2796 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 2227 2248 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 1679 1700 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 4419 4440 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 5652 5673 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 3871 3892 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF12245 Bacterial Ig-like domain (group 3) 3323 3344 1.2 T 05-07-2017 IPR022038 Bacterial Ig-like domain K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 5504 5623 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 3449 3568 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 1394 1513 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 7086 7104 - T 05-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 7059 7077 - T 05-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 3723 3842 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 709 828 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 2216 2335 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 4545 4664 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 3038 3157 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 5821 5868 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 2807 2854 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 3766 3813 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 752 799 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 2670 2717 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 6251 6288 3.4 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 3903 3950 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 1848 1895 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 4999 5046 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 1574 1621 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 6102 6139 19.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 5547 5594 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 2533 2580 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 3629 3676 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 3081 3128 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 5410 5457 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 420 523 0.7 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 889 936 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 1985 2032 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 1437 1484 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 4862 4909 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 1300 1347 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 4314 4361 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 5273 5320 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 2259 2306 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 3355 3402 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 3218 3265 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 4177 4224 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 4451 4498 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 158 251 33.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 2396 2443 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 2122 2169 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 1026 1073 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 4725 4772 18.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 4040 4087 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 3492 3539 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 5684 5731 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 1163 1210 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 282 386 0.11 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 5136 5183 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 4588 4635 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 2944 2991 18.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF03160 Calx-beta domain 1711 1758 30.0 T 05-07-2017 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 2764 2883 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 4271 4390 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 4682 4801 1.7E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 6042 6143 4.71E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 2490 2609 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SMART SM00327 6605 6789 1.3E-12 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 5915 6033 6.28E-5 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 5641 5760 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 2627 2746 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 2901 3020 1.7E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 3997 4116 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 7068 7086 - T 05-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 1942 2061 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 983 1102 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 4956 5075 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 6327 6430 1.44E-5 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 1257 1376 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 7077 7095 - T 05-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 1668 1787 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 432 542 2.22E-11 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 3586 3705 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Gene3D G3DSA:3.40.50.410 6606 6757 5.2E-12 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 Pfam PF13519 von Willebrand factor type A domain 6610 6720 6.7E-11 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 5367 5486 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 3312 3431 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 5230 5349 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF51120 6974 7000 3.4E-23 T 05-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF51120 7030 7167 3.4E-23 T 05-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 295 405 1.05E-11 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 3860 3979 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 846 965 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF53300 6606 6761 2.22E-20 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 2079 2198 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 4408 4527 1.96E-7 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 159 270 2.35E-10 T 05-07-2017 K08M4_RS07945 1046426a882b32789192cc2d426db884 7236 SUPERFAMILY SSF141072 2353 2472 1.96E-7 T 05-07-2017 K08M4_RS21325 e29d16fde81618996c9d563dd673582b 329 Pfam PF00581 Rhodanese-like domain 117 210 1.4E-9 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS21325 e29d16fde81618996c9d563dd673582b 329 SUPERFAMILY SSF52821 94 239 1.07E-32 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS21325 e29d16fde81618996c9d563dd673582b 329 Gene3D G3DSA:3.40.250.10 92 226 5.7E-42 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS21325 e29d16fde81618996c9d563dd673582b 329 SMART SM00450 113 214 4.6E-24 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS21325 e29d16fde81618996c9d563dd673582b 329 Hamap MF_00469 UPF0176 protein YceA [yceA]. 2 254 45.655 T 05-07-2017 IPR020936 Uncharacterised protein family UPF0176 K08M4_RS20985 a09eea2c9e437437cdb3a43ee67034be 279 SMART SM00342 193 276 3.4E-31 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS20985 a09eea2c9e437437cdb3a43ee67034be 279 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 230 272 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 K08M4_RS20985 a09eea2c9e437437cdb3a43ee67034be 279 Pfam PF12833 Helix-turn-helix domain 199 277 2.0E-20 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS20985 a09eea2c9e437437cdb3a43ee67034be 279 Gene3D G3DSA:1.10.10.60 176 229 1.2E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20985 a09eea2c9e437437cdb3a43ee67034be 279 SUPERFAMILY SSF46689 229 278 8.06E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20985 a09eea2c9e437437cdb3a43ee67034be 279 SUPERFAMILY SSF46689 179 227 4.75E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20985 a09eea2c9e437437cdb3a43ee67034be 279 Gene3D G3DSA:1.10.10.60 230 277 3.6E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20985 a09eea2c9e437437cdb3a43ee67034be 279 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 260 276 4.6E-7 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS20985 a09eea2c9e437437cdb3a43ee67034be 279 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 245 260 4.6E-7 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS01480 e5c71adc0da53de8829791db1bafbd48 274 SUPERFAMILY SSF50249 2 125 9.6E-49 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS01480 e5c71adc0da53de8829791db1bafbd48 274 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 2.5E-56 T 05-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 K08M4_RS01480 e5c71adc0da53de8829791db1bafbd48 274 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 1.4E-129 T 05-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01480 e5c71adc0da53de8829791db1bafbd48 274 SMART SM01382 124 252 1.6E-91 T 05-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 K08M4_RS01480 e5c71adc0da53de8829791db1bafbd48 274 PIRSF PIRSF002158 13 274 5.6E-99 T 05-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01480 e5c71adc0da53de8829791db1bafbd48 274 Gene3D G3DSA:2.40.50.140 1 114 1.3E-49 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS01480 e5c71adc0da53de8829791db1bafbd48 274 Gene3D G3DSA:4.10.950.10 196 273 1.5E-35 T 05-07-2017 IPR014726 Ribosomal protein L2, domain 3 K08M4_RS01480 e5c71adc0da53de8829791db1bafbd48 274 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.871 T 05-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01480 e5c71adc0da53de8829791db1bafbd48 274 SMART SM01383 42 118 8.7E-45 T 05-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01480 e5c71adc0da53de8829791db1bafbd48 274 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 05-07-2017 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01480 e5c71adc0da53de8829791db1bafbd48 274 Gene3D G3DSA:2.30.30.30 119 195 9.8E-33 T 05-07-2017 IPR014722 Ribosomal protein L2 domain 2 K08M4_RS01480 e5c71adc0da53de8829791db1bafbd48 274 SUPERFAMILY SSF50104 127 272 3.61E-61 T 05-07-2017 IPR008991 Translation protein SH3-like domain K08M4_RS01480 e5c71adc0da53de8829791db1bafbd48 274 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 1.3E-32 T 05-07-2017 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS00995 07d8e3f091f3117f92e6c07ac174106a 162 Gene3D G3DSA:1.10.10.10 12 84 9.3E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS00995 07d8e3f091f3117f92e6c07ac174106a 162 SUPERFAMILY SSF46785 12 82 1.22E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS00995 07d8e3f091f3117f92e6c07ac174106a 162 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 97 137 1.0E-12 T 05-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 K08M4_RS00995 07d8e3f091f3117f92e6c07ac174106a 162 Hamap MF_00173 Arginine repressor [argR]. 1 162 39.449 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 K08M4_RS00995 07d8e3f091f3117f92e6c07ac174106a 162 Pfam PF01316 Arginine repressor, DNA binding domain 18 80 6.7E-14 T 05-07-2017 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 K08M4_RS00995 07d8e3f091f3117f92e6c07ac174106a 162 SUPERFAMILY SSF55252 92 156 7.98E-16 T 05-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 K08M4_RS00995 07d8e3f091f3117f92e6c07ac174106a 162 Pfam PF02863 Arginine repressor, C-terminal domain 95 152 4.0E-16 T 05-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 K08M4_RS00995 07d8e3f091f3117f92e6c07ac174106a 162 Gene3D G3DSA:3.30.1360.40 88 154 2.6E-19 T 05-07-2017 IPR024946 Arginine repressor C-terminal-like domain K08M4_RS00995 07d8e3f091f3117f92e6c07ac174106a 162 PRINTS PR01467 Bacterial arginine repressor signature 33 46 1.6E-18 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 K08M4_RS00995 07d8e3f091f3117f92e6c07ac174106a 162 PRINTS PR01467 Bacterial arginine repressor signature 128 143 1.6E-18 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 K08M4_RS00995 07d8e3f091f3117f92e6c07ac174106a 162 PRINTS PR01467 Bacterial arginine repressor signature 98 111 1.6E-18 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 K08M4_RS00995 07d8e3f091f3117f92e6c07ac174106a 162 PRINTS PR01467 Bacterial arginine repressor signature 50 65 1.6E-18 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 K08M4_RS06610 5d35abba9d81b57acac9f31bd8b12fc7 279 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 7.0E-18 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS06610 5d35abba9d81b57acac9f31bd8b12fc7 279 Pfam PF03466 LysR substrate binding domain 112 261 1.0E-10 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS06610 5d35abba9d81b57acac9f31bd8b12fc7 279 Gene3D G3DSA:1.10.10.10 1 80 7.3E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06610 5d35abba9d81b57acac9f31bd8b12fc7 279 Gene3D G3DSA:3.40.190.10 156 245 7.3E-18 T 05-07-2017 K08M4_RS06610 5d35abba9d81b57acac9f31bd8b12fc7 279 SUPERFAMILY SSF46785 1 81 5.25E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06610 5d35abba9d81b57acac9f31bd8b12fc7 279 Gene3D G3DSA:3.40.190.10 262 277 5.6E-8 T 05-07-2017 K08M4_RS06610 5d35abba9d81b57acac9f31bd8b12fc7 279 Gene3D G3DSA:3.40.190.10 95 155 5.6E-8 T 05-07-2017 K08M4_RS06610 5d35abba9d81b57acac9f31bd8b12fc7 279 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.3E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS06610 5d35abba9d81b57acac9f31bd8b12fc7 279 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.3E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS06610 5d35abba9d81b57acac9f31bd8b12fc7 279 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.3E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS06610 5d35abba9d81b57acac9f31bd8b12fc7 279 SUPERFAMILY SSF53850 94 273 8.51E-25 T 05-07-2017 K08M4_RS16895 d32e09f524eadc2c5df7da2a0b508435 336 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 7 333 1.8E-150 T 05-07-2017 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative K08M4_RS16895 d32e09f524eadc2c5df7da2a0b508435 336 Gene3D G3DSA:3.40.190.10 2 123 2.2E-34 T 05-07-2017 K08M4_RS16895 d32e09f524eadc2c5df7da2a0b508435 336 Gene3D G3DSA:3.40.190.10 266 317 2.2E-34 T 05-07-2017 K08M4_RS16895 d32e09f524eadc2c5df7da2a0b508435 336 Gene3D G3DSA:3.40.190.10 131 265 3.4E-40 T 05-07-2017 K08M4_RS16895 d32e09f524eadc2c5df7da2a0b508435 336 PIRSF PIRSF002825 1 329 6.4E-76 T 05-07-2017 IPR026045 Ferric binding protein K08M4_RS16895 d32e09f524eadc2c5df7da2a0b508435 336 Pfam PF13343 Bacterial extracellular solute-binding protein 75 294 2.7E-25 T 05-07-2017 K08M4_RS16895 d32e09f524eadc2c5df7da2a0b508435 336 SUPERFAMILY SSF53850 24 325 5.93E-59 T 05-07-2017 K08M4_RS16855 ec4333140206bd236318eb12eb146886 219 Pfam PF02254 TrkA-N domain 6 121 1.3E-27 T 05-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 K08M4_RS16855 ec4333140206bd236318eb12eb146886 219 Gene3D G3DSA:3.30.70.1450 146 215 6.4E-11 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS16855 ec4333140206bd236318eb12eb146886 219 SUPERFAMILY SSF51735 4 134 1.0E-33 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS16855 ec4333140206bd236318eb12eb146886 219 SUPERFAMILY SSF116726 132 212 4.71E-13 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS16855 ec4333140206bd236318eb12eb146886 219 Gene3D G3DSA:3.40.50.720 3 139 8.1E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS16205 b4d9961b0f58aa77c984740a10c5030b 884 SUPERFAMILY SSF55874 536 685 5.5E-27 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS16205 b4d9961b0f58aa77c984740a10c5030b 884 SMART SM00388 463 532 1.8E-4 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS16205 b4d9961b0f58aa77c984740a10c5030b 884 SMART SM00387 576 685 1.4E-23 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS16205 b4d9961b0f58aa77c984740a10c5030b 884 Gene3D G3DSA:3.30.565.10 521 686 2.3E-26 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS16205 b4d9961b0f58aa77c984740a10c5030b 884 SMART SM00448 756 866 2.2E-23 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS16205 b4d9961b0f58aa77c984740a10c5030b 884 PRINTS PR00344 Bacterial sensor protein C-terminal signature 633 643 2.5E-9 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS16205 b4d9961b0f58aa77c984740a10c5030b 884 PRINTS PR00344 Bacterial sensor protein C-terminal signature 645 663 2.5E-9 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS16205 b4d9961b0f58aa77c984740a10c5030b 884 PRINTS PR00344 Bacterial sensor protein C-terminal signature 669 682 2.5E-9 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS16205 b4d9961b0f58aa77c984740a10c5030b 884 PRINTS PR00344 Bacterial sensor protein C-terminal signature 615 629 2.5E-9 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS16205 b4d9961b0f58aa77c984740a10c5030b 884 SUPERFAMILY SSF52172 756 872 2.56E-28 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS16205 b4d9961b0f58aa77c984740a10c5030b 884 SUPERFAMILY SSF47384 454 515 2.35E-6 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS16205 b4d9961b0f58aa77c984740a10c5030b 884 Gene3D G3DSA:1.10.287.130 458 520 3.0E-6 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS16205 b4d9961b0f58aa77c984740a10c5030b 884 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 583 682 1.8E-14 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS16205 b4d9961b0f58aa77c984740a10c5030b 884 Gene3D G3DSA:3.40.50.2300 756 878 9.5E-31 T 05-07-2017 K08M4_RS16205 b4d9961b0f58aa77c984740a10c5030b 884 Pfam PF00072 Response regulator receiver domain 758 866 1.7E-20 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS01350 e52c2228b9478dc099af092157204e11 210 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 71 89 - T 05-07-2017 IPR018488 Cyclic nucleotide-binding, conserved site K08M4_RS01350 e52c2228b9478dc099af092157204e11 210 ProSitePatterns PS00042 Crp-type HTH domain signature. 168 191 - T 05-07-2017 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 K08M4_RS01350 e52c2228b9478dc099af092157204e11 210 Gene3D G3DSA:1.10.10.10 144 207 1.1E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS01350 e52c2228b9478dc099af092157204e11 210 SMART SM00419 160 208 4.2E-17 T 05-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 K08M4_RS01350 e52c2228b9478dc099af092157204e11 210 Gene3D G3DSA:2.60.120.10 6 143 1.2E-43 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS01350 e52c2228b9478dc099af092157204e11 210 SMART SM00100 2 122 3.7E-27 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain K08M4_RS01350 e52c2228b9478dc099af092157204e11 210 SUPERFAMILY SSF46785 139 207 3.95E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS01350 e52c2228b9478dc099af092157204e11 210 SUPERFAMILY SSF51206 8 137 1.13E-34 T 05-07-2017 IPR018490 Cyclic nucleotide-binding-like K08M4_RS01350 e52c2228b9478dc099af092157204e11 210 Pfam PF00325 Bacterial regulatory proteins, crp family 166 197 8.6E-16 T 05-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 K08M4_RS01350 e52c2228b9478dc099af092157204e11 210 Pfam PF00027 Cyclic nucleotide-binding domain 23 109 6.8E-23 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain K08M4_RS01350 e52c2228b9478dc099af092157204e11 210 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 182 197 5.7E-11 T 05-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 K08M4_RS01350 e52c2228b9478dc099af092157204e11 210 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 166 182 5.7E-11 T 05-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 K08M4_RS01350 e52c2228b9478dc099af092157204e11 210 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 30 46 - T 05-07-2017 IPR018488 Cyclic nucleotide-binding, conserved site K08M4_RS03780 44cef3ae158dfd0eafab8583258fa5a3 363 SUPERFAMILY SSF52540 3 301 1.37E-83 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03780 44cef3ae158dfd0eafab8583258fa5a3 363 Gene3D G3DSA:3.10.20.30 267 363 1.5E-49 T 05-07-2017 IPR012675 Beta-grasp domain K08M4_RS03780 44cef3ae158dfd0eafab8583258fa5a3 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 3.6E-34 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS03780 44cef3ae158dfd0eafab8583258fa5a3 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 3.6E-34 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS03780 44cef3ae158dfd0eafab8583258fa5a3 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 3.6E-34 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS03780 44cef3ae158dfd0eafab8583258fa5a3 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.6E-34 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS03780 44cef3ae158dfd0eafab8583258fa5a3 363 Gene3D G3DSA:3.40.50.300 4 131 4.0E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03780 44cef3ae158dfd0eafab8583258fa5a3 363 Gene3D G3DSA:3.40.50.300 201 266 4.0E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03780 44cef3ae158dfd0eafab8583258fa5a3 363 Gene3D G3DSA:1.10.150.300 132 200 2.8E-25 T 05-07-2017 IPR023192 TGS-like domain K08M4_RS03780 44cef3ae158dfd0eafab8583258fa5a3 363 Pfam PF01926 50S ribosome-binding GTPase 5 122 9.0E-22 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS03780 44cef3ae158dfd0eafab8583258fa5a3 363 PIRSF PIRSF006641 1 363 3.8E-157 T 05-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 K08M4_RS03780 44cef3ae158dfd0eafab8583258fa5a3 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 2.4E-168 T 05-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 K08M4_RS03780 44cef3ae158dfd0eafab8583258fa5a3 363 SUPERFAMILY SSF81271 279 363 2.62E-36 T 05-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 K08M4_RS03780 44cef3ae158dfd0eafab8583258fa5a3 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 4.2E-39 T 05-07-2017 IPR013029 Domain of unknown function DUF933 K08M4_RS03780 44cef3ae158dfd0eafab8583258fa5a3 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 45.241 T 05-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 K08M4_RS15535 7dfcdf5f89bc2bfbe82fe0b338a40add 286 ProSitePatterns PS00221 MIP family signature. 68 76 - T 05-07-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS15535 7dfcdf5f89bc2bfbe82fe0b338a40add 286 PRINTS PR00783 Major intrinsic protein family signature 11 30 4.5E-51 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS15535 7dfcdf5f89bc2bfbe82fe0b338a40add 286 PRINTS PR00783 Major intrinsic protein family signature 87 106 4.5E-51 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS15535 7dfcdf5f89bc2bfbe82fe0b338a40add 286 PRINTS PR00783 Major intrinsic protein family signature 186 208 4.5E-51 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS15535 7dfcdf5f89bc2bfbe82fe0b338a40add 286 PRINTS PR00783 Major intrinsic protein family signature 153 171 4.5E-51 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS15535 7dfcdf5f89bc2bfbe82fe0b338a40add 286 PRINTS PR00783 Major intrinsic protein family signature 50 74 4.5E-51 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS15535 7dfcdf5f89bc2bfbe82fe0b338a40add 286 PRINTS PR00783 Major intrinsic protein family signature 235 255 4.5E-51 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS15535 7dfcdf5f89bc2bfbe82fe0b338a40add 286 Pfam PF00230 Major intrinsic protein 6 252 4.5E-64 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS15535 7dfcdf5f89bc2bfbe82fe0b338a40add 286 SUPERFAMILY SSF81338 9 256 7.06E-74 T 05-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 K08M4_RS15535 7dfcdf5f89bc2bfbe82fe0b338a40add 286 TIGRFAM TIGR00861 MIP: MIP family channel proteins 15 252 8.3E-69 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS15535 7dfcdf5f89bc2bfbe82fe0b338a40add 286 Gene3D G3DSA:1.20.1080.10 6 256 3.9E-83 T 05-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 K08M4_RS21685 413d595ae7bd42238388a916bb662ff6 312 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 81 282 1.1E-51 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS21685 413d595ae7bd42238388a916bb662ff6 312 Pfam PF02355 Protein export membrane protein 111 287 9.6E-56 T 05-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial K08M4_RS21685 413d595ae7bd42238388a916bb662ff6 312 Pfam PF07549 SecD/SecF GG Motif 40 65 8.8E-9 T 05-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site K08M4_RS21685 413d595ae7bd42238388a916bb662ff6 312 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 16 295 22.363 T 05-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 K08M4_RS21685 413d595ae7bd42238388a916bb662ff6 312 PRINTS PR01755 Bacterial translocase SecF protein signature 153 167 8.9E-28 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS21685 413d595ae7bd42238388a916bb662ff6 312 PRINTS PR01755 Bacterial translocase SecF protein signature 233 248 8.9E-28 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS21685 413d595ae7bd42238388a916bb662ff6 312 PRINTS PR01755 Bacterial translocase SecF protein signature 43 58 8.9E-28 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS21685 413d595ae7bd42238388a916bb662ff6 312 PRINTS PR01755 Bacterial translocase SecF protein signature 201 219 8.9E-28 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS21685 413d595ae7bd42238388a916bb662ff6 312 SUPERFAMILY SSF82866 107 285 3.53E-33 T 05-07-2017 K08M4_RS21685 413d595ae7bd42238388a916bb662ff6 312 Gene3D G3DSA:1.20.1640.10 128 282 1.0E-23 T 05-07-2017 K08M4_RS21685 413d595ae7bd42238388a916bb662ff6 312 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 44 283 2.4E-70 T 05-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 K08M4_RS06125 7b30d2bf3c3b12a473fa0184df71e006 104 Pfam PF04266 ASCH domain 7 95 2.6E-15 T 05-07-2017 IPR007374 ASCH domain K08M4_RS06125 7b30d2bf3c3b12a473fa0184df71e006 104 PIRSF PIRSF029143 2 104 4.2E-46 T 05-07-2017 IPR008314 Uncharacterised conserved protein UCP029143 K08M4_RS06125 7b30d2bf3c3b12a473fa0184df71e006 104 SUPERFAMILY SSF88697 4 104 2.24E-35 T 05-07-2017 IPR015947 PUA-like domain K08M4_RS06125 7b30d2bf3c3b12a473fa0184df71e006 104 Hamap MF_00684 UPF0267 protein YqfB [yqfB]. 3 104 31.071 T 05-07-2017 IPR008314 Uncharacterised conserved protein UCP029143 K08M4_RS06125 7b30d2bf3c3b12a473fa0184df71e006 104 Gene3D G3DSA:2.30.130.30 4 104 1.3E-45 T 05-07-2017 K08M4_RS06125 7b30d2bf3c3b12a473fa0184df71e006 104 SMART SM01022 7 104 7.3E-27 T 05-07-2017 IPR007374 ASCH domain K08M4_RS05910 b0e4ce846f514da05029c5aa4e63705a 594 Pfam PF00005 ABC transporter 368 512 7.9E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS05910 b0e4ce846f514da05029c5aa4e63705a 594 Pfam PF00664 ABC transporter transmembrane region 24 292 6.1E-42 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS05910 b0e4ce846f514da05029c5aa4e63705a 594 SUPERFAMILY SSF90123 5 330 2.62E-54 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS05910 b0e4ce846f514da05029c5aa4e63705a 594 Gene3D G3DSA:3.40.50.300 353 588 5.4E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05910 b0e4ce846f514da05029c5aa4e63705a 594 SMART SM00382 375 558 3.1E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS05910 b0e4ce846f514da05029c5aa4e63705a 594 ProSitePatterns PS00211 ABC transporters family signature. 484 498 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS05910 b0e4ce846f514da05029c5aa4e63705a 594 Gene3D G3DSA:1.20.1560.10 10 330 2.8E-46 T 05-07-2017 K08M4_RS05910 b0e4ce846f514da05029c5aa4e63705a 594 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 20 554 4.2E-178 T 05-07-2017 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 K08M4_RS05910 b0e4ce846f514da05029c5aa4e63705a 594 SUPERFAMILY SSF52540 346 581 5.53E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05150 de3d718c53578e12fabddc85cc16e681 321 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 210 315 1.6E-20 T 05-07-2017 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS05150 de3d718c53578e12fabddc85cc16e681 321 Pfam PF13177 DNA polymerase III, delta subunit 12 164 3.3E-42 T 05-07-2017 K08M4_RS05150 de3d718c53578e12fabddc85cc16e681 321 Gene3D G3DSA:3.40.50.300 7 164 5.5E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05150 de3d718c53578e12fabddc85cc16e681 321 Gene3D G3DSA:1.20.272.10 208 320 1.2E-24 T 05-07-2017 K08M4_RS05150 de3d718c53578e12fabddc85cc16e681 321 SUPERFAMILY SSF48019 213 320 1.51E-14 T 05-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 K08M4_RS05150 de3d718c53578e12fabddc85cc16e681 321 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 12 199 2.3E-54 T 05-07-2017 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS05150 de3d718c53578e12fabddc85cc16e681 321 SUPERFAMILY SSF52540 6 203 7.6E-39 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12460 ae06391be36e2739b789d27dc8b388ef 1515 Pfam PF04898 Glutamate synthase central domain 472 756 6.3E-115 T 05-07-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 K08M4_RS12460 ae06391be36e2739b789d27dc8b388ef 1515 Pfam PF00310 Glutamine amidotransferases class-II 21 443 2.0E-184 T 05-07-2017 IPR017932 Glutamine amidotransferase type 2 domain K08M4_RS12460 ae06391be36e2739b789d27dc8b388ef 1515 Gene3D G3DSA:3.60.20.10 21 453 2.0E-182 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS12460 ae06391be36e2739b789d27dc8b388ef 1515 Pfam PF01645 Conserved region in glutamate synthase 817 1187 3.8E-150 T 05-07-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 K08M4_RS12460 ae06391be36e2739b789d27dc8b388ef 1515 Gene3D G3DSA:2.160.20.60 1241 1510 1.0E-106 T 05-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 K08M4_RS12460 ae06391be36e2739b789d27dc8b388ef 1515 SUPERFAMILY SSF51395 451 1221 4.89E-265 T 05-07-2017 K08M4_RS12460 ae06391be36e2739b789d27dc8b388ef 1515 Gene3D G3DSA:3.20.20.70 856 1223 7.8E-178 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS12460 ae06391be36e2739b789d27dc8b388ef 1515 SUPERFAMILY SSF56235 21 447 5.56E-152 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS12460 ae06391be36e2739b789d27dc8b388ef 1515 Pfam PF01493 GXGXG motif 1267 1452 4.6E-83 T 05-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 K08M4_RS12460 ae06391be36e2739b789d27dc8b388ef 1515 Gene3D G3DSA:3.20.20.70 454 806 6.0E-107 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS12460 ae06391be36e2739b789d27dc8b388ef 1515 SUPERFAMILY SSF69336 1236 1498 1.31E-95 T 05-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 K08M4_RS01545 9a7a12ae5565ba859b1e97211eac49dc 117 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 117 2.2E-42 T 05-07-2017 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01545 9a7a12ae5565ba859b1e97211eac49dc 117 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 117 25.62 T 05-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01545 9a7a12ae5565ba859b1e97211eac49dc 117 SUPERFAMILY SSF53137 3 115 1.81E-50 T 05-07-2017 K08M4_RS01545 9a7a12ae5565ba859b1e97211eac49dc 117 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 117 1.3E-42 T 05-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01545 9a7a12ae5565ba859b1e97211eac49dc 117 Gene3D G3DSA:3.30.420.100 24 117 4.8E-36 T 05-07-2017 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 ProSitePatterns PS00433 Phosphofructokinase signature. 244 262 - T 05-07-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 32 45 3.3E-83 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 3.3E-83 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 3.3E-83 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 3.3E-83 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 3.3E-83 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 3.3E-83 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 7 26 3.3E-83 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 240 262 3.3E-83 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 94 110 3.3E-83 T 05-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 2 320 46.703 T 05-07-2017 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 SUPERFAMILY SSF53784 3 306 3.66E-111 T 05-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 PIRSF PIRSF000532 1 320 7.9E-127 T 05-07-2017 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 Gene3D G3DSA:3.40.50.450 3 191 6.5E-74 T 05-07-2017 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 4 300 7.0E-131 T 05-07-2017 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 K08M4_RS01080 5495ba64e530f6e0857551768c425fb3 320 Pfam PF00365 Phosphofructokinase 4 276 4.0E-109 T 05-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 K08M4_RS17720 e50bfca995711d95450d67b0babdeca5 530 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 280 295 - T 05-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 K08M4_RS17720 e50bfca995711d95450d67b0babdeca5 530 Gene3D G3DSA:3.40.50.300 192 366 9.6E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17720 e50bfca995711d95450d67b0babdeca5 530 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 218 231 - T 05-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 K08M4_RS17720 e50bfca995711d95450d67b0babdeca5 530 SUPERFAMILY SSF52540 193 429 5.33E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17720 e50bfca995711d95450d67b0babdeca5 530 Pfam PF01590 GAF domain 25 156 7.2E-6 T 05-07-2017 IPR003018 GAF domain GO:0005515 K08M4_RS17720 e50bfca995711d95450d67b0babdeca5 530 SMART SM00382 214 357 1.3E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS17720 e50bfca995711d95450d67b0babdeca5 530 SUPERFAMILY SSF55781 7 182 8.72E-16 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS17720 e50bfca995711d95450d67b0babdeca5 530 Gene3D G3DSA:3.30.450.40 9 174 1.3E-13 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS17720 e50bfca995711d95450d67b0babdeca5 530 SMART SM00065 21 169 0.0026 T 05-07-2017 IPR003018 GAF domain GO:0005515 K08M4_RS17720 e50bfca995711d95450d67b0babdeca5 530 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 407 416 - T 05-07-2017 IPR025944 Sigma-54 interaction domain, conserved site K08M4_RS17720 e50bfca995711d95450d67b0babdeca5 530 Gene3D G3DSA:1.10.8.60 367 414 8.3E-18 T 05-07-2017 K08M4_RS17720 e50bfca995711d95450d67b0babdeca5 530 SUPERFAMILY SSF46689 470 518 1.52E-5 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS17720 e50bfca995711d95450d67b0babdeca5 530 Gene3D G3DSA:1.10.10.60 415 518 1.6E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS17720 e50bfca995711d95450d67b0babdeca5 530 Pfam PF00158 Sigma-54 interaction domain 194 360 7.6E-67 T 05-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 K08M4_RS15500 60682dd76da0a99c6351620a358e9c12 175 Gene3D G3DSA:2.60.40.1610 91 171 1.2E-13 T 05-07-2017 IPR010679 Domain of unknown function DUF1254 K08M4_RS15500 60682dd76da0a99c6351620a358e9c12 175 SUPERFAMILY SSF160935 15 173 3.92E-30 T 05-07-2017 K08M4_RS15500 60682dd76da0a99c6351620a358e9c12 175 Pfam PF06863 Protein of unknown function (DUF1254) 78 173 2.6E-24 T 05-07-2017 IPR010679 Domain of unknown function DUF1254 K08M4_RS12975 8ab7c77da0842edf2b77eb0fbb05b431 126 Pfam PF04379 Protein of unknown function (DUF525) 18 103 1.5E-33 T 05-07-2017 IPR007474 ApaG domain K08M4_RS12975 8ab7c77da0842edf2b77eb0fbb05b431 126 Hamap MF_00791 Protein ApaG [apaG]. 1 126 30.499 T 05-07-2017 IPR023065 Uncharacterised protein family ApaG K08M4_RS12975 8ab7c77da0842edf2b77eb0fbb05b431 126 SUPERFAMILY SSF110069 5 126 3.66E-46 T 05-07-2017 IPR007474 ApaG domain K08M4_RS12975 8ab7c77da0842edf2b77eb0fbb05b431 126 Gene3D G3DSA:2.60.40.1470 4 125 1.1E-43 T 05-07-2017 IPR007474 ApaG domain K08M4_RS06470 a0bc75e3758507dadb61a8fd6a4bd7ce 98 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 2 94 3.8E-49 T 05-07-2017 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 K08M4_RS06470 a0bc75e3758507dadb61a8fd6a4bd7ce 98 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 05-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 K08M4_RS06470 a0bc75e3758507dadb61a8fd6a4bd7ce 98 SMART SM00411 3 92 8.6E-41 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS06470 a0bc75e3758507dadb61a8fd6a4bd7ce 98 Gene3D G3DSA:4.10.520.10 2 93 2.7E-36 T 05-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 K08M4_RS06470 a0bc75e3758507dadb61a8fd6a4bd7ce 98 SUPERFAMILY SSF47729 3 95 2.36E-32 T 05-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 K08M4_RS06470 a0bc75e3758507dadb61a8fd6a4bd7ce 98 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 3.4E-17 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS06470 a0bc75e3758507dadb61a8fd6a4bd7ce 98 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 3.4E-17 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS06470 a0bc75e3758507dadb61a8fd6a4bd7ce 98 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 3.4E-17 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS06470 a0bc75e3758507dadb61a8fd6a4bd7ce 98 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 1 97 29.929 T 05-07-2017 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 K08M4_RS06470 a0bc75e3758507dadb61a8fd6a4bd7ce 98 Pfam PF00216 Bacterial DNA-binding protein 3 91 7.5E-32 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS01760 67726cb0ee43e2fa10f86e0a0e2290de 330 Pfam PF13343 Bacterial extracellular solute-binding protein 76 298 1.8E-22 T 05-07-2017 K08M4_RS01760 67726cb0ee43e2fa10f86e0a0e2290de 330 Gene3D G3DSA:3.40.190.10 4 123 1.5E-21 T 05-07-2017 K08M4_RS01760 67726cb0ee43e2fa10f86e0a0e2290de 330 Gene3D G3DSA:3.40.190.10 262 320 1.5E-21 T 05-07-2017 K08M4_RS01760 67726cb0ee43e2fa10f86e0a0e2290de 330 Gene3D G3DSA:3.40.190.10 126 261 9.6E-27 T 05-07-2017 K08M4_RS01760 67726cb0ee43e2fa10f86e0a0e2290de 330 SUPERFAMILY SSF53850 24 325 1.32E-68 T 05-07-2017 K08M4_RS01760 67726cb0ee43e2fa10f86e0a0e2290de 330 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 21 324 1.8E-143 T 05-07-2017 IPR005948 Thiamine ABC transporter periplasmic binding protein GO:0005215|GO:0006810|GO:0015888|GO:0030288|GO:0030975 K08M4_RS01760 67726cb0ee43e2fa10f86e0a0e2290de 330 TIGRFAM TIGR01276 thiB: thiamin/thiamin pyrophosphate ABC transporter, thiamin/thiamin pyrophospate-binding protein 18 329 2.0E-147 T 05-07-2017 IPR005967 Proteobacterial thiamine ABC transporter, periplasmic binding protein GO:0005524|GO:0015888|GO:0030288|GO:0048502 K08M4_RS08035 67a6de127b35c25e8a2cd4c207e042db 1057 SUPERFAMILY SSF109604 679 762 7.22E-8 T 05-07-2017 K08M4_RS08035 67a6de127b35c25e8a2cd4c207e042db 1057 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 301 515 2.6E-21 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS08035 67a6de127b35c25e8a2cd4c207e042db 1057 Pfam PF13487 HD domain 911 976 3.4E-20 T 05-07-2017 K08M4_RS08035 67a6de127b35c25e8a2cd4c207e042db 1057 SMART SM00062 294 517 8.7E-4 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS08035 67a6de127b35c25e8a2cd4c207e042db 1057 Gene3D G3DSA:3.40.190.10 478 516 1.4E-12 T 05-07-2017 K08M4_RS08035 67a6de127b35c25e8a2cd4c207e042db 1057 Gene3D G3DSA:3.40.190.10 296 379 1.4E-12 T 05-07-2017 K08M4_RS08035 67a6de127b35c25e8a2cd4c207e042db 1057 SUPERFAMILY SSF109604 909 1023 1.79E-6 T 05-07-2017 K08M4_RS08035 67a6de127b35c25e8a2cd4c207e042db 1057 SUPERFAMILY SSF53850 287 517 7.41E-32 T 05-07-2017 K08M4_RS08035 67a6de127b35c25e8a2cd4c207e042db 1057 Gene3D G3DSA:1.10.3210.10 673 756 2.0E-5 T 05-07-2017 IPR006674 HD domain K08M4_RS08035 67a6de127b35c25e8a2cd4c207e042db 1057 Gene3D G3DSA:3.40.190.10 383 456 3.5E-7 T 05-07-2017 K08M4_RS08035 67a6de127b35c25e8a2cd4c207e042db 1057 Gene3D G3DSA:3.30.450.20 163 227 1.0E-13 T 05-07-2017 K08M4_RS08035 67a6de127b35c25e8a2cd4c207e042db 1057 Gene3D G3DSA:3.30.450.20 78 117 1.0E-13 T 05-07-2017 K08M4_RS01610 1921f63bfd5a1856f310950b47250f05 192 Pfam PF08525 Opacity-associated protein A N-terminal motif 44 69 2.6E-7 T 05-07-2017 IPR013731 Opacity-associated protein A, N-terminal K08M4_RS01610 1921f63bfd5a1856f310950b47250f05 192 Pfam PF04225 Opacity-associated protein A LysM-like domain 108 192 2.4E-38 T 05-07-2017 IPR007340 Opacity-associated protein A K08M4_RS09125 800a6aa33a0605da2a3ba3c1f1f0ef50 170 Pfam PF13740 ACT domain 4 74 3.9E-10 T 05-07-2017 K08M4_RS09125 800a6aa33a0605da2a3ba3c1f1f0ef50 170 SUPERFAMILY SSF55021 88 167 4.12E-9 T 05-07-2017 K08M4_RS09125 800a6aa33a0605da2a3ba3c1f1f0ef50 170 Gene3D G3DSA:3.30.70.260 85 168 3.3E-15 T 05-07-2017 K08M4_RS09125 800a6aa33a0605da2a3ba3c1f1f0ef50 170 PIRSF PIRSF028103 1 169 2.5E-37 T 05-07-2017 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 K08M4_RS18410 66e6fe1ec714845dc52fce9bcae40287 475 PIRSF PIRSF006603 12 474 5.5E-65 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS18410 66e6fe1ec714845dc52fce9bcae40287 475 TIGRFAM TIGR00797 matE: MATE efflux family protein 36 433 1.0E-52 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS18410 66e6fe1ec714845dc52fce9bcae40287 475 Pfam PF01554 MatE 36 195 1.4E-29 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS18410 66e6fe1ec714845dc52fce9bcae40287 475 Pfam PF01554 MatE 276 425 1.9E-17 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS06675 1b47349797648ad3793b6c6afc3e1a0a 249 SMART SM00028 149 182 0.043 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS06675 1b47349797648ad3793b6c6afc3e1a0a 249 SMART SM00028 45 78 0.76 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS06675 1b47349797648ad3793b6c6afc3e1a0a 249 SMART SM00028 79 112 0.0012 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS06675 1b47349797648ad3793b6c6afc3e1a0a 249 SMART SM00028 113 146 29.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS06675 1b47349797648ad3793b6c6afc3e1a0a 249 Gene3D G3DSA:1.25.40.10 129 191 6.6E-10 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS06675 1b47349797648ad3793b6c6afc3e1a0a 249 TIGRFAM TIGR02521 type_IV_pilW: type IV pilus biogenesis/stability protein PilW 17 245 1.4E-75 T 05-07-2017 IPR013360 Pilus biogenesis/stability type IV, PilW K08M4_RS06675 1b47349797648ad3793b6c6afc3e1a0a 249 Pfam PF13424 Tetratricopeptide repeat 114 179 8.1E-9 T 05-07-2017 K08M4_RS06675 1b47349797648ad3793b6c6afc3e1a0a 249 Pfam PF13432 Tetratricopeptide repeat 50 109 1.3E-4 T 05-07-2017 K08M4_RS06675 1b47349797648ad3793b6c6afc3e1a0a 249 Gene3D G3DSA:1.25.40.10 48 128 3.2E-19 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS06675 1b47349797648ad3793b6c6afc3e1a0a 249 SUPERFAMILY SSF81901 41 207 1.26E-23 T 05-07-2017 K08M4_RS07740 9f457e344dec0341dcbc2a5b6b4d3eb3 199 Pfam PF13505 Outer membrane protein beta-barrel domain 7 199 5.4E-17 T 05-07-2017 IPR027385 Outer membrane protein beta-barrel K08M4_RS07740 9f457e344dec0341dcbc2a5b6b4d3eb3 199 SUPERFAMILY SSF56925 31 199 1.1E-17 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS07740 9f457e344dec0341dcbc2a5b6b4d3eb3 199 Gene3D G3DSA:2.40.160.20 16 199 8.9E-17 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1303 21.36 T 05-07-2017 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 SUPERFAMILY SSF52317 1044 1302 7.26E-99 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 SUPERFAMILY SSF56042 433 616 1.94E-52 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 3 1301 0.0 T 05-07-2017 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 SUPERFAMILY SSF55326 619 817 4.71E-70 T 05-07-2017 K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 Gene3D G3DSA:3.30.1330.10 646 811 1.6E-16 T 05-07-2017 IPR016188 PurM-like, N-terminal domain K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 Gene3D G3DSA:3.30.1330.10 212 423 5.9E-39 T 05-07-2017 IPR016188 PurM-like, N-terminal domain K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 Pfam PF02769 AIR synthase related protein, C-terminal domain 841 974 4.2E-14 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 Pfam PF02769 AIR synthase related protein, C-terminal domain 433 590 6.4E-27 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 SUPERFAMILY SSF109736 155 221 1.57E-20 T 05-07-2017 K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 SMART SM01211 1047 1302 3.4E-156 T 05-07-2017 K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 SUPERFAMILY SSF55326 222 429 2.51E-65 T 05-07-2017 K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1047 1300 1.4E-106 T 05-07-2017 K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 SUPERFAMILY SSF56042 831 1041 1.06E-54 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 Gene3D G3DSA:3.40.50.880 1048 1271 6.2E-13 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS11630 0be616a155d0509451e8cb7789c129ac 1303 SUPERFAMILY SSF82697 1 151 4.66E-49 T 05-07-2017 K08M4_RS19425 868f8b9fcbd88f3053cb3d48e8175013 631 Gene3D G3DSA:3.10.105.10 419 588 9.9E-48 T 05-07-2017 K08M4_RS19425 868f8b9fcbd88f3053cb3d48e8175013 631 Gene3D G3DSA:3.10.105.10 337 386 9.9E-48 T 05-07-2017 K08M4_RS19425 868f8b9fcbd88f3053cb3d48e8175013 631 Gene3D G3DSA:3.90.76.10 93 243 2.7E-34 T 05-07-2017 K08M4_RS19425 868f8b9fcbd88f3053cb3d48e8175013 631 SUPERFAMILY SSF53850 78 618 7.6E-114 T 05-07-2017 K08M4_RS19425 868f8b9fcbd88f3053cb3d48e8175013 631 PIRSF PIRSF002741 43 622 3.0E-123 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 K08M4_RS19425 868f8b9fcbd88f3053cb3d48e8175013 631 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 126 534 6.3E-77 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain K08M4_RS15215 d4e65f8378bc78c9faeec61ca4cfd8cc 280 TIGRFAM TIGR03416 ABC_choXWV_perm: choline ABC transporter, permease protein 6 272 1.2E-127 T 05-07-2017 IPR017784 ABC transporter, choline, permease protein K08M4_RS15215 d4e65f8378bc78c9faeec61ca4cfd8cc 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 267 6.8E-26 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS15215 d4e65f8378bc78c9faeec61ca4cfd8cc 280 SUPERFAMILY SSF161098 88 272 3.66E-39 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS15215 d4e65f8378bc78c9faeec61ca4cfd8cc 280 Gene3D G3DSA:1.10.3720.10 86 268 9.4E-36 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS19420 9784f6143ccab88885a8ebc85ddedd53 362 SUPERFAMILY SSF161098 126 344 7.46E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS19420 9784f6143ccab88885a8ebc85ddedd53 362 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 150 357 2.6E-35 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS19420 9784f6143ccab88885a8ebc85ddedd53 362 Gene3D G3DSA:1.10.3720.10 127 354 7.2E-16 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS15680 f67df8a077c2deb36f21e40837b4977b 215 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 5 201 4.1E-29 T 05-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS15680 f67df8a077c2deb36f21e40837b4977b 215 SUPERFAMILY SSF51366 1 214 3.05E-34 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 K08M4_RS15680 f67df8a077c2deb36f21e40837b4977b 215 Gene3D G3DSA:3.20.20.70 1 214 1.1E-71 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS15680 f67df8a077c2deb36f21e40837b4977b 215 SMART SM00934 5 206 8.1E-25 T 05-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS15865 7cf838a10468ff9caae16d0144696c56 306 Pfam PF04018 Domain of unknown function (DUF368) 13 257 1.6E-96 T 05-07-2017 IPR007163 Protein of unknown function DUF368 K08M4_RS06845 fe15b76c6e20b516bbeb1405b184c26d 583 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 409 479 8.3E-12 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 K08M4_RS06845 fe15b76c6e20b516bbeb1405b184c26d 583 Gene3D G3DSA:3.40.50.300 393 496 6.3E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06845 fe15b76c6e20b516bbeb1405b184c26d 583 Gene3D G3DSA:3.40.50.300 50 194 6.3E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06845 fe15b76c6e20b516bbeb1405b184c26d 583 Gene3D G3DSA:3.40.50.300 260 276 6.3E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06845 fe15b76c6e20b516bbeb1405b184c26d 583 Gene3D G3DSA:3.40.50.300 1 49 7.2E-4 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06845 fe15b76c6e20b516bbeb1405b184c26d 583 SUPERFAMILY SSF52540 390 502 2.07E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06845 fe15b76c6e20b516bbeb1405b184c26d 583 SUPERFAMILY SSF52540 37 98 2.07E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06845 fe15b76c6e20b516bbeb1405b184c26d 583 SUPERFAMILY SSF52540 148 222 2.07E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05065 9bf44d5887642e4c7fdbf43f7821dfda 201 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 29 201 1.5E-67 T 05-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 K08M4_RS05065 9bf44d5887642e4c7fdbf43f7821dfda 201 SUPERFAMILY SSF52540 12 201 6.11E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05065 9bf44d5887642e4c7fdbf43f7821dfda 201 PIRSF PIRSF015617 6 201 1.6E-64 T 05-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 K08M4_RS05065 9bf44d5887642e4c7fdbf43f7821dfda 201 Pfam PF12557 Cob(I)alamin adenosyltransferase N terminal 1 26 1.7E-7 T 05-07-2017 IPR025826 Cob(I)alamin adenosyltransferase N-terminal domain KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 K08M4_RS05065 9bf44d5887642e4c7fdbf43f7821dfda 201 Gene3D G3DSA:3.40.50.300 7 201 1.7E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05065 9bf44d5887642e4c7fdbf43f7821dfda 201 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 33 201 2.5E-58 T 05-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 K08M4_RS03645 cfb5319d93caedca7f3fa4668aa7e373 156 Pfam PF07295 Zinc-ribbon containing domain 14 152 6.9E-49 T 05-07-2017 IPR009912 Zinc-ribbon containing domain K08M4_RS10610 7fd1219a89d66771b7ad4949868fd295 548 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 40 179 8.5E-39 T 05-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS10610 7fd1219a89d66771b7ad4949868fd295 548 SUPERFAMILY SSF53738 305 446 4.71E-31 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS10610 7fd1219a89d66771b7ad4949868fd295 548 Gene3D G3DSA:3.40.120.10 30 225 6.7E-60 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS10610 7fd1219a89d66771b7ad4949868fd295 548 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 317 1.7E-16 T 05-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS10610 7fd1219a89d66771b7ad4949868fd295 548 Gene3D G3DSA:3.40.120.10 226 317 1.1E-43 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS10610 7fd1219a89d66771b7ad4949868fd295 548 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 320 438 2.5E-28 T 05-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS10610 7fd1219a89d66771b7ad4949868fd295 548 Gene3D G3DSA:3.30.310.50 466 543 2.9E-30 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS10610 7fd1219a89d66771b7ad4949868fd295 548 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 05-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS10610 7fd1219a89d66771b7ad4949868fd295 548 SUPERFAMILY SSF53738 27 235 3.06E-51 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS10610 7fd1219a89d66771b7ad4949868fd295 548 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 1 543 0.0 T 05-07-2017 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 K08M4_RS10610 7fd1219a89d66771b7ad4949868fd295 548 SUPERFAMILY SSF55957 433 543 3.14E-20 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS10610 7fd1219a89d66771b7ad4949868fd295 548 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 490 537 2.4E-8 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS10610 7fd1219a89d66771b7ad4949868fd295 548 Gene3D G3DSA:3.40.120.10 318 441 1.8E-34 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS10610 7fd1219a89d66771b7ad4949868fd295 548 SUPERFAMILY SSF53738 209 317 2.35E-7 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS19990 b5642f5bb916b699d6f5803b7435f980 154 Pfam PF05926 Phage head completion protein (GPL) 15 153 1.8E-39 T 05-07-2017 IPR009225 Bacteriophage head completion protein GpL GO:0019069 K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Gene3D G3DSA:3.40.50.1820 2627 2772 2.0E-59 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Gene3D G3DSA:3.40.50.1820 4796 4834 2.0E-59 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 SUPERFAMILY SSF158842 3242 3515 8.63E-105 T 05-07-2017 K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF11713 Peptidase C80 family 3781 3943 7.5E-47 T 05-07-2017 IPR020974 CGT/MARTX, cysteine protease (CPD) domain K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 SUPERFAMILY SSF53474 2656 2770 1.76E-21 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Gene3D G3DSA:2.150.10.10 4572 4795 6.1E-17 T 05-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF12146 Serine aminopeptidase, S33 2659 2775 4.3E-9 T 05-07-2017 IPR022742 Serine aminopeptidase, S33 K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 893 907 23.0 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 855 872 0.48 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 798 812 0.049 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 1122 1139 0.095 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 1198 1214 0.0027 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 601 617 9.8 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 1084 1099 0.26 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 161 184 0.0011 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 756 766 4.6 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 874 888 1.2 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 1028 1040 0.39 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 1217 1233 0.2 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 1160 1176 0.041 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 121 138 0.052 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 1312 1328 1.7 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 969 981 8.7 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 641 655 3.8 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 738 751 0.57 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 1181 1196 0.015 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 581 598 2.1 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 141 157 0.0039 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 1008 1023 9.0 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 779 793 0.49 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 1293 1310 0.0078 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 1141 1156 0.052 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 988 1003 0.17 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 817 832 0.062 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 101 118 0.57 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 1107 1119 6.1 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 836 852 0.16 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 275 290 0.0031 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 207 224 0.52 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 1064 1076 5.4 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 187 204 1.5 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 950 965 1.4 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 1255 1272 2.1 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 255 272 1.3 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 931 948 9.8 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 621 638 0.034 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 1046 1057 4.2 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF07634 RtxA repeat 912 929 0.25 T 05-07-2017 IPR011509 RtxA toxin K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 SUPERFAMILY SSF51120 4510 4604 6.63E-6 T 05-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 SUPERFAMILY SSF51120 4595 4804 7.19E-14 T 05-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 Pfam PF11647 C-terminal region of Pasteurella multocida toxin residues 569-1285 3256 3318 1.1E-17 T 05-07-2017 IPR020972 Dermonecrotic/RTX toxin C-terminal K08M4_RS15565 a91be9cc28c8d9e71ed67910cf1f7829 4872 SUPERFAMILY SSF159501 3518 3740 1.05E-70 T 05-07-2017 K08M4_RS02345 fd4d7314ea7698b4f8cefe37e8703226 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 1.5E-17 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS02345 fd4d7314ea7698b4f8cefe37e8703226 298 Gene3D G3DSA:3.40.190.10 93 198 6.4E-40 T 05-07-2017 K08M4_RS02345 fd4d7314ea7698b4f8cefe37e8703226 298 SUPERFAMILY SSF53850 95 294 4.52E-24 T 05-07-2017 K08M4_RS02345 fd4d7314ea7698b4f8cefe37e8703226 298 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 4 295 1.6E-107 T 05-07-2017 IPR017685 HTH-type transcriptional regulator ArgP K08M4_RS02345 fd4d7314ea7698b4f8cefe37e8703226 298 Hamap MF_00513 HTH-type transcriptional regulator ArgP [argP]. 1 298 55.552 T 05-07-2017 IPR023490 HTH-type transcriptional regulator ArgP, Gammaproteobacteria K08M4_RS02345 fd4d7314ea7698b4f8cefe37e8703226 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.7E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS02345 fd4d7314ea7698b4f8cefe37e8703226 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.7E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS02345 fd4d7314ea7698b4f8cefe37e8703226 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.7E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS02345 fd4d7314ea7698b4f8cefe37e8703226 298 Gene3D G3DSA:1.10.10.10 4 79 2.8E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS02345 fd4d7314ea7698b4f8cefe37e8703226 298 Pfam PF03466 LysR substrate binding domain 95 276 1.3E-15 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS02345 fd4d7314ea7698b4f8cefe37e8703226 298 SUPERFAMILY SSF46785 4 112 3.45E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS14860 49447ec4e4d42ea26b1e874422e65d20 507 SMART SM00382 210 390 2.2E-4 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS14860 49447ec4e4d42ea26b1e874422e65d20 507 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 493 8.0E-208 T 05-07-2017 IPR004482 Mg chelatase-related protein K08M4_RS14860 49447ec4e4d42ea26b1e874422e65d20 507 SUPERFAMILY SSF54211 2 167 1.86E-28 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS14860 49447ec4e4d42ea26b1e874422e65d20 507 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 401 493 2.3E-31 T 05-07-2017 IPR025158 Mg chelatase-related protein, C-terminal domain K08M4_RS14860 49447ec4e4d42ea26b1e874422e65d20 507 SUPERFAMILY SSF52540 188 500 2.62E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14860 49447ec4e4d42ea26b1e874422e65d20 507 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 3.8E-46 T 05-07-2017 K08M4_RS14860 49447ec4e4d42ea26b1e874422e65d20 507 Gene3D G3DSA:3.30.230.10 6 151 3.1E-25 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup K08M4_RS14860 49447ec4e4d42ea26b1e874422e65d20 507 Gene3D G3DSA:3.40.50.300 188 385 2.8E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14860 49447ec4e4d42ea26b1e874422e65d20 507 Pfam PF01078 Magnesium chelatase, subunit ChlI 190 390 5.4E-89 T 05-07-2017 IPR000523 Magnesium chelatase ChlI domain K08M4_RS08330 f43f0d636568df830c83b6c846fdafcd 1360 Gene3D G3DSA:3.40.50.300 325 471 2.7E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08330 f43f0d636568df830c83b6c846fdafcd 1360 SMART SM00847 517 621 7.4E-36 T 05-07-2017 IPR007502 Helicase-associated domain GO:0004386 K08M4_RS08330 f43f0d636568df830c83b6c846fdafcd 1360 Pfam PF11898 Domain of unknown function (DUF3418) 774 1358 2.0E-230 T 05-07-2017 IPR024590 RNA helicase HrpA, C-terminal K08M4_RS08330 f43f0d636568df830c83b6c846fdafcd 1360 Pfam PF00270 DEAD/DEAH box helicase 140 286 1.3E-8 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS08330 f43f0d636568df830c83b6c846fdafcd 1360 SMART SM00487 128 312 2.3E-30 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS08330 f43f0d636568df830c83b6c846fdafcd 1360 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 67 1358 0.0 T 05-07-2017 IPR010222 RNA helicase HrpA GO:0004004 K08M4_RS08330 f43f0d636568df830c83b6c846fdafcd 1360 SMART SM00382 145 437 7.3E-6 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS08330 f43f0d636568df830c83b6c846fdafcd 1360 SUPERFAMILY SSF52540 127 629 6.02E-113 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08330 f43f0d636568df830c83b6c846fdafcd 1360 Pfam PF04408 Helicase associated domain (HA2) 519 619 1.9E-17 T 05-07-2017 IPR007502 Helicase-associated domain GO:0004386 K08M4_RS08330 f43f0d636568df830c83b6c846fdafcd 1360 Pfam PF00271 Helicase conserved C-terminal domain 338 456 3.4E-11 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS08330 f43f0d636568df830c83b6c846fdafcd 1360 Gene3D G3DSA:3.40.50.300 130 286 4.8E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08330 f43f0d636568df830c83b6c846fdafcd 1360 SMART SM00490 357 457 1.1E-14 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS08330 f43f0d636568df830c83b6c846fdafcd 1360 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 668 760 6.6E-18 T 05-07-2017 IPR011709 Domain of unknown function DUF1605 K08M4_RS17145 08f351d2e3feb2c6fb0c00e205c2857c 224 Gene3D G3DSA:1.10.150.240 15 91 1.2E-19 T 05-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 K08M4_RS17145 08f351d2e3feb2c6fb0c00e205c2857c 224 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 61 195 4.7E-10 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS17145 08f351d2e3feb2c6fb0c00e205c2857c 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 70 194 6.1E-22 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS17145 08f351d2e3feb2c6fb0c00e205c2857c 224 Gene3D G3DSA:3.40.50.1000 92 222 7.4E-41 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS17145 08f351d2e3feb2c6fb0c00e205c2857c 224 SUPERFAMILY SSF56784 2 222 1.02E-48 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS17145 08f351d2e3feb2c6fb0c00e205c2857c 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 1.1E-8 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS17145 08f351d2e3feb2c6fb0c00e205c2857c 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 184 197 1.1E-8 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS17145 08f351d2e3feb2c6fb0c00e205c2857c 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 1.1E-8 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS17145 08f351d2e3feb2c6fb0c00e205c2857c 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.1E-8 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS17145 08f351d2e3feb2c6fb0c00e205c2857c 224 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 97 189 2.4E-15 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS17145 08f351d2e3feb2c6fb0c00e205c2857c 224 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 3 220 2.5E-81 T 05-07-2017 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 K08M4_RS18305 fe16ef40c1ee1e502f8b54ac29b26049 291 Pfam PF00950 ABC 3 transport family 22 285 1.9E-56 T 05-07-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 K08M4_RS18305 fe16ef40c1ee1e502f8b54ac29b26049 291 Gene3D G3DSA:1.10.3470.10 60 282 2.2E-9 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS18305 fe16ef40c1ee1e502f8b54ac29b26049 291 SUPERFAMILY SSF81345 15 281 9.42E-35 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS12600 aae605e6737460651ba312295219fc99 585 Gene3D G3DSA:3.40.710.10 254 574 2.3E-91 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS12600 aae605e6737460651ba312295219fc99 585 Pfam PF00905 Penicillin binding protein transpeptidase domain 272 568 5.3E-76 T 05-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 K08M4_RS12600 aae605e6737460651ba312295219fc99 585 SUPERFAMILY SSF56519 75 246 7.72E-44 T 05-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 K08M4_RS12600 aae605e6737460651ba312295219fc99 585 Gene3D G3DSA:3.90.1310.10 154 253 9.1E-32 T 05-07-2017 K08M4_RS12600 aae605e6737460651ba312295219fc99 585 SUPERFAMILY SSF56601 247 576 1.3E-93 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS12600 aae605e6737460651ba312295219fc99 585 Pfam PF03717 Penicillin-binding Protein dimerisation domain 79 233 2.1E-20 T 05-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 K08M4_RS04370 38eb72e7c90c64e4c67614134a60f783 154 Gene3D G3DSA:3.40.50.1240 1 154 6.4E-37 T 05-07-2017 IPR029033 Histidine phosphatase superfamily K08M4_RS04370 38eb72e7c90c64e4c67614134a60f783 154 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 78 2.4E-7 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 K08M4_RS04370 38eb72e7c90c64e4c67614134a60f783 154 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 1 154 4.4E-36 T 05-07-2017 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0008969 K08M4_RS04370 38eb72e7c90c64e4c67614134a60f783 154 SMART SM00855 2 116 9.6E-4 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 K08M4_RS04370 38eb72e7c90c64e4c67614134a60f783 154 SUPERFAMILY SSF53254 1 145 6.85E-19 T 05-07-2017 IPR029033 Histidine phosphatase superfamily K08M4_RS15145 f5e4bde0a976025f5d2db7123200829c 648 SUPERFAMILY SSF47384 394 463 3.14E-7 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS15145 f5e4bde0a976025f5d2db7123200829c 648 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 596 7.9E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS15145 f5e4bde0a976025f5d2db7123200829c 648 PRINTS PR00344 Bacterial sensor protein C-terminal signature 597 615 7.9E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS15145 f5e4bde0a976025f5d2db7123200829c 648 PRINTS PR00344 Bacterial sensor protein C-terminal signature 621 634 7.9E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS15145 f5e4bde0a976025f5d2db7123200829c 648 PRINTS PR00344 Bacterial sensor protein C-terminal signature 568 582 7.9E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS15145 f5e4bde0a976025f5d2db7123200829c 648 SUPERFAMILY SSF103190 66 191 3.34E-16 T 05-07-2017 IPR029151 Periplasmic sensor domain-like K08M4_RS15145 f5e4bde0a976025f5d2db7123200829c 648 PIRSF PIRSF036431 6 644 1.1E-158 T 05-07-2017 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) K08M4_RS15145 f5e4bde0a976025f5d2db7123200829c 648 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 513 636 2.1E-15 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS15145 f5e4bde0a976025f5d2db7123200829c 648 SUPERFAMILY SSF55874 465 638 4.45E-33 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS15145 f5e4bde0a976025f5d2db7123200829c 648 Gene3D G3DSA:3.30.450.20 90 183 1.2E-7 T 05-07-2017 K08M4_RS15145 f5e4bde0a976025f5d2db7123200829c 648 SMART SM00388 399 467 0.0039 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS15145 f5e4bde0a976025f5d2db7123200829c 648 Gene3D G3DSA:3.30.565.10 473 635 5.6E-36 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS15145 f5e4bde0a976025f5d2db7123200829c 648 SMART SM00387 510 637 2.6E-22 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS15145 f5e4bde0a976025f5d2db7123200829c 648 Pfam PF02743 Cache domain 39 222 3.9E-14 T 05-07-2017 IPR033479 Double Cache domain 1 K08M4_RS14515 ed842c3f632942412945fbac772e7b02 107 Hamap MF_01088 Universal stress protein B [uspB]. 1 107 36.694 T 05-07-2017 IPR019598 Universal stress protein B K08M4_RS14515 ed842c3f632942412945fbac772e7b02 107 Pfam PF10625 Universal stress protein B (UspB) 1 106 1.6E-52 T 05-07-2017 IPR019598 Universal stress protein B K08M4_RS03660 4cb239155373a295aedf3a78b50da756 153 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 113 123 - T 05-07-2017 IPR020549 Endoribonuclease YbeY, conserved site K08M4_RS03660 4cb239155373a295aedf3a78b50da756 153 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 4 147 24.674 T 05-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 K08M4_RS03660 4cb239155373a295aedf3a78b50da756 153 SUPERFAMILY SSF55486 4 150 2.93E-49 T 05-07-2017 K08M4_RS03660 4cb239155373a295aedf3a78b50da756 153 Gene3D G3DSA:3.40.390.30 12 151 5.9E-51 T 05-07-2017 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 K08M4_RS03660 4cb239155373a295aedf3a78b50da756 153 Pfam PF02130 Uncharacterized protein family UPF0054 19 142 2.1E-39 T 05-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 K08M4_RS03660 4cb239155373a295aedf3a78b50da756 153 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 39 143 1.2E-37 T 05-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 K08M4_RS12650 23869d51ec112a1eb1bec74cbf62fe81 211 SUPERFAMILY SSF47616 82 208 4.55E-23 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS12650 23869d51ec112a1eb1bec74cbf62fe81 211 SUPERFAMILY SSF52833 11 110 8.16E-22 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS12650 23869d51ec112a1eb1bec74cbf62fe81 211 Pfam PF00043 Glutathione S-transferase, C-terminal domain 105 194 1.7E-7 T 05-07-2017 IPR004046 Glutathione S-transferase, C-terminal K08M4_RS12650 23869d51ec112a1eb1bec74cbf62fe81 211 Gene3D G3DSA:3.40.30.10 7 100 1.2E-28 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS12650 23869d51ec112a1eb1bec74cbf62fe81 211 Pfam PF13417 Glutathione S-transferase, N-terminal domain 13 87 1.4E-16 T 05-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 K08M4_RS12650 23869d51ec112a1eb1bec74cbf62fe81 211 Gene3D G3DSA:1.20.1050.10 101 208 5.2E-15 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS08370 5fc60a3663d88ee10eda1b3a295da072 374 Pfam PF00005 ABC transporter 21 162 2.7E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS08370 5fc60a3663d88ee10eda1b3a295da072 374 Gene3D G3DSA:2.40.50.140 293 352 2.1E-10 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS08370 5fc60a3663d88ee10eda1b3a295da072 374 Gene3D G3DSA:2.40.50.100 354 368 1.9E-14 T 05-07-2017 K08M4_RS08370 5fc60a3663d88ee10eda1b3a295da072 374 Gene3D G3DSA:2.40.50.100 245 292 1.9E-14 T 05-07-2017 K08M4_RS08370 5fc60a3663d88ee10eda1b3a295da072 374 Pfam PF08402 TOBE domain 288 360 6.7E-10 T 05-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 K08M4_RS08370 5fc60a3663d88ee10eda1b3a295da072 374 Gene3D G3DSA:3.40.50.300 4 242 1.6E-71 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08370 5fc60a3663d88ee10eda1b3a295da072 374 SMART SM00382 29 217 2.7E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS08370 5fc60a3663d88ee10eda1b3a295da072 374 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS08370 5fc60a3663d88ee10eda1b3a295da072 374 SUPERFAMILY SSF50331 242 369 2.92E-26 T 05-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal K08M4_RS08370 5fc60a3663d88ee10eda1b3a295da072 374 SUPERFAMILY SSF52540 4 248 4.38E-82 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21360 5f43250f1a62d41c3a6b9e89e9e0b660 464 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 36 426 1.1E-136 T 05-07-2017 K08M4_RS21360 5f43250f1a62d41c3a6b9e89e9e0b660 464 PIRSF PIRSF002808 8 460 5.3E-108 T 05-07-2017 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 K08M4_RS21360 5f43250f1a62d41c3a6b9e89e9e0b660 464 Gene3D G3DSA:1.20.1250.20 252 455 1.3E-29 T 05-07-2017 K08M4_RS21360 5f43250f1a62d41c3a6b9e89e9e0b660 464 Gene3D G3DSA:1.20.1250.20 29 227 2.6E-33 T 05-07-2017 K08M4_RS21360 5f43250f1a62d41c3a6b9e89e9e0b660 464 SUPERFAMILY SSF103473 16 447 1.12E-59 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS21360 5f43250f1a62d41c3a6b9e89e9e0b660 464 Pfam PF07690 Major Facilitator Superfamily 35 396 1.5E-34 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS21360 5f43250f1a62d41c3a6b9e89e9e0b660 464 ProSitePatterns PS00942 glpT family of transporters signature. 156 172 - T 05-07-2017 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-3229133|Reactome: R-HSA-70153 K08M4_RS06405 9702fa9a45d7a44494fa6e8bb065b150 119 PIRSF PIRSF039020 1 119 1.8E-37 T 05-07-2017 IPR026275 Glyoxalase/bleomycin resistance protein/dioxygenase K08M4_RS06405 9702fa9a45d7a44494fa6e8bb065b150 119 SUPERFAMILY SSF54593 4 118 7.56E-19 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS06405 9702fa9a45d7a44494fa6e8bb065b150 119 Gene3D G3DSA:3.10.180.10 2 118 5.7E-17 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS06405 9702fa9a45d7a44494fa6e8bb065b150 119 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 116 2.4E-5 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain K08M4_RS14210 172fb6ddeb32a6b3eb3efa07b27612d6 349 PIRSF PIRSF002786 15 341 2.5E-64 T 05-07-2017 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 K08M4_RS14210 172fb6ddeb32a6b3eb3efa07b27612d6 349 SUPERFAMILY SSF158544 115 226 1.62E-30 T 05-07-2017 K08M4_RS14210 172fb6ddeb32a6b3eb3efa07b27612d6 349 Pfam PF03934 Type II secretion system (T2SS), protein K 44 331 1.4E-87 T 05-07-2017 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 K08M4_RS14210 172fb6ddeb32a6b3eb3efa07b27612d6 349 Gene3D G3DSA:1.10.40.60 229 298 2.4E-28 T 05-07-2017 K08M4_RS14210 172fb6ddeb32a6b3eb3efa07b27612d6 349 SUPERFAMILY SSF158544 229 297 3.92E-20 T 05-07-2017 K08M4_RS14210 172fb6ddeb32a6b3eb3efa07b27612d6 349 Gene3D G3DSA:3.30.1300.30 40 118 1.5E-31 T 05-07-2017 K08M4_RS14210 172fb6ddeb32a6b3eb3efa07b27612d6 349 SUPERFAMILY SSF54523 50 114 5.02E-36 T 05-07-2017 K08M4_RS14210 172fb6ddeb32a6b3eb3efa07b27612d6 349 SUPERFAMILY SSF54523 298 338 5.02E-36 T 05-07-2017 K08M4_RS14210 172fb6ddeb32a6b3eb3efa07b27612d6 349 Gene3D G3DSA:1.10.40.60 119 227 2.5E-35 T 05-07-2017 K08M4_RS10460 a4149befe54f09d56341638cfc0d5ae6 389 Hamap MF_01899 Ribonuclease D [rnd]. 20 389 45.429 T 05-07-2017 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 K08M4_RS10460 a4149befe54f09d56341638cfc0d5ae6 389 SUPERFAMILY SSF47819 313 388 1.83E-20 T 05-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 K08M4_RS10460 a4149befe54f09d56341638cfc0d5ae6 389 Pfam PF00570 HRDC domain 230 295 2.0E-10 T 05-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 K08M4_RS10460 a4149befe54f09d56341638cfc0d5ae6 389 TIGRFAM TIGR01388 rnd: ribonuclease D 22 386 5.0E-147 T 05-07-2017 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 K08M4_RS10460 a4149befe54f09d56341638cfc0d5ae6 389 SUPERFAMILY SSF47819 210 318 3.14E-25 T 05-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 K08M4_RS10460 a4149befe54f09d56341638cfc0d5ae6 389 Gene3D G3DSA:3.30.420.10 19 194 1.6E-17 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS10460 a4149befe54f09d56341638cfc0d5ae6 389 Pfam PF01612 3'-5' exonuclease 20 187 2.7E-40 T 05-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 K08M4_RS10460 a4149befe54f09d56341638cfc0d5ae6 389 SMART SM00474 20 188 1.3E-43 T 05-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 K08M4_RS10460 a4149befe54f09d56341638cfc0d5ae6 389 SUPERFAMILY SSF53098 18 226 4.35E-70 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 Gene3D G3DSA:2.40.30.10 303 400 9.6E-33 T 05-07-2017 K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 Pfam PF14492 Elongation Factor G, domain II 400 473 4.5E-29 T 05-07-2017 IPR009022 Elongation factor G, III-V domain K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.2E-13 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 PRINTS PR00315 GTP-binding elongation factor signature 75 85 1.2E-13 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 PRINTS PR00315 GTP-binding elongation factor signature 55 63 1.2E-13 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 PRINTS PR00315 GTP-binding elongation factor signature 127 136 1.2E-13 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 SMART SM00838 596 683 2.7E-43 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 175 2.0E-24 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 Hamap MF_00054_B Elongation factor G [fusA]. 3 687 98.952 T 05-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 Pfam PF03144 Elongation factor Tu domain 2 320 387 2.4E-15 T 05-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 Gene3D G3DSA:3.40.50.300 2 283 4.2E-95 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 SMART SM00889 476 594 1.4E-61 T 05-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 SUPERFAMILY SSF54211 475 594 8.85E-40 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 SUPERFAMILY SSF50447 261 398 8.39E-30 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 05-07-2017 IPR031157 Tr-type G domain, conserved site K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 Pfam PF03764 Elongation factor G, domain IV 475 593 6.5E-43 T 05-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 SUPERFAMILY SSF52540 3 277 9.94E-99 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 SUPERFAMILY SSF54980 400 477 5.76E-21 T 05-07-2017 IPR009022 Elongation factor G, III-V domain K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 Gene3D G3DSA:3.30.70.870 401 476 1.0E-31 T 05-07-2017 K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 TIGRFAM TIGR00484 EF-G: translation elongation factor G 3 688 6.1E-291 T 05-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 Pfam PF00679 Elongation factor G C-terminus 596 682 8.5E-28 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 Pfam PF00009 Elongation factor Tu GTP binding domain 6 277 6.3E-61 T 05-07-2017 K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 SUPERFAMILY SSF54980 599 689 6.47E-28 T 05-07-2017 IPR009022 Elongation factor G, III-V domain K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 Gene3D G3DSA:3.30.70.240 596 681 3.5E-30 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain K08M4_RS03270 01acb00766613ede4457a9f5bdf3f11d 695 Gene3D G3DSA:3.30.230.10 480 595 3.7E-44 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup K08M4_RS14280 225bd1d7d7c9c023ae5bb731adeb0610 144 SUPERFAMILY SSF69500 2 143 1.44E-52 T 05-07-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain K08M4_RS14280 225bd1d7d7c9c023ae5bb731adeb0610 144 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 3 142 5.2E-49 T 05-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 K08M4_RS14280 225bd1d7d7c9c023ae5bb731adeb0610 144 Gene3D G3DSA:3.50.80.10 3 143 6.6E-52 T 05-07-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain K08M4_RS14280 225bd1d7d7c9c023ae5bb731adeb0610 144 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 2 144 1.4E-60 T 05-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 K08M4_RS14280 225bd1d7d7c9c023ae5bb731adeb0610 144 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 144 32.131 T 05-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 K08M4_RS03245 5c73c6c45f559b696d287c196c0cbb35 239 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 62 77 - T 05-07-2017 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS03245 5c73c6c45f559b696d287c196c0cbb35 239 SUPERFAMILY SSF53167 3 234 7.59E-93 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 K08M4_RS03245 5c73c6c45f559b696d287c196c0cbb35 239 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 2 235 51.243 T 05-07-2017 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 K08M4_RS03245 5c73c6c45f559b696d287c196c0cbb35 239 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 5 234 8.5E-118 T 05-07-2017 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 K08M4_RS03245 5c73c6c45f559b696d287c196c0cbb35 239 Gene3D G3DSA:3.40.50.1580 10 233 9.5E-83 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 K08M4_RS03245 5c73c6c45f559b696d287c196c0cbb35 239 Pfam PF01048 Phosphorylase superfamily 15 218 5.9E-41 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 K08M4_RS17600 ddb611937f2e272db0e416ea5083c01d 415 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 290 402 2.4E-31 T 05-07-2017 IPR006056 RidA family K08M4_RS17600 ddb611937f2e272db0e416ea5083c01d 415 SUPERFAMILY SSF55298 7 135 1.18E-30 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS17600 ddb611937f2e272db0e416ea5083c01d 415 SUPERFAMILY SSF55298 287 410 2.67E-36 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS17600 ddb611937f2e272db0e416ea5083c01d 415 SUPERFAMILY SSF55298 145 272 1.73E-31 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS17600 ddb611937f2e272db0e416ea5083c01d 415 Gene3D G3DSA:3.30.1330.40 7 139 5.9E-42 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS17600 ddb611937f2e272db0e416ea5083c01d 415 Gene3D G3DSA:3.30.1330.40 287 412 2.7E-43 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS17600 ddb611937f2e272db0e416ea5083c01d 415 Gene3D G3DSA:3.30.1330.40 145 274 2.9E-39 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS17600 ddb611937f2e272db0e416ea5083c01d 415 Pfam PF01042 Endoribonuclease L-PSP 291 402 2.2E-27 T 05-07-2017 IPR006175 YjgF/YER057c/UK114 family K08M4_RS17600 ddb611937f2e272db0e416ea5083c01d 415 Pfam PF01042 Endoribonuclease L-PSP 28 128 4.2E-23 T 05-07-2017 IPR006175 YjgF/YER057c/UK114 family K08M4_RS17600 ddb611937f2e272db0e416ea5083c01d 415 Pfam PF01042 Endoribonuclease L-PSP 170 264 7.9E-23 T 05-07-2017 IPR006175 YjgF/YER057c/UK114 family K08M4_RS21085 e43e064f092776de797d9321a42d3c81 443 Gene3D G3DSA:2.40.30.10 237 307 6.6E-14 T 05-07-2017 K08M4_RS21085 e43e064f092776de797d9321a42d3c81 443 SUPERFAMILY SSF52343 319 438 3.01E-16 T 05-07-2017 K08M4_RS21085 e43e064f092776de797d9321a42d3c81 443 Gene3D G3DSA:3.40.50.80 308 433 1.2E-14 T 05-07-2017 K08M4_RS21085 e43e064f092776de797d9321a42d3c81 443 Pfam PF01794 Ferric reductase like transmembrane component 44 179 4.7E-17 T 05-07-2017 IPR013130 Ferric reductase transmembrane component-like domain K08M4_RS21085 e43e064f092776de797d9321a42d3c81 443 Pfam PF08022 FAD-binding domain 237 315 5.6E-9 T 05-07-2017 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 K08M4_RS21085 e43e064f092776de797d9321a42d3c81 443 SUPERFAMILY SSF63380 230 315 1.12E-16 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 ProSitePatterns PS01047 Heavy-metal-associated domain. 81 110 - T 05-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 470 476 - T 05-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 SUPERFAMILY SSF56784 562 773 1.78E-48 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 SUPERFAMILY SSF56784 466 486 1.78E-48 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 Gene3D G3DSA:3.40.50.1000 603 739 1.1E-43 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 Gene3D G3DSA:3.40.50.1000 441 481 1.1E-43 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 217 775 2.2E-172 T 05-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 Pfam PF00122 E1-E2 ATPase 238 459 8.4E-64 T 05-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 SUPERFAMILY SSF55008 78 140 9.16E-14 T 05-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 PRINTS PR00941 Cadmium-transporting ATPase signature 352 366 1.8E-5 T 05-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 PRINTS PR00941 Cadmium-transporting ATPase signature 252 272 1.8E-5 T 05-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 PRINTS PR00941 Cadmium-transporting ATPase signature 90 111 1.8E-5 T 05-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 240 752 4.3E-78 T 05-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 Gene3D G3DSA:3.40.1110.10 482 602 3.4E-14 T 05-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 Pfam PF00403 Heavy-metal-associated domain 81 130 7.0E-11 T 05-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 Gene3D G3DSA:3.30.70.100 78 141 6.9E-16 T 05-07-2017 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 SUPERFAMILY SSF81653 270 367 6.93E-22 T 05-07-2017 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 217 518 6.8E-95 T 05-07-2017 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 Gene3D G3DSA:2.70.150.10 220 368 4.9E-26 T 05-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 317 331 2.0E-27 T 05-07-2017 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 696 708 2.0E-27 T 05-07-2017 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 468 482 2.0E-27 T 05-07-2017 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 600 611 2.0E-27 T 05-07-2017 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 622 632 2.0E-27 T 05-07-2017 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 673 692 2.0E-27 T 05-07-2017 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 SUPERFAMILY SSF81665 368 462 2.35E-19 T 05-07-2017 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 SUPERFAMILY SSF81665 220 271 2.35E-19 T 05-07-2017 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 SUPERFAMILY SSF81665 722 761 2.35E-19 T 05-07-2017 K08M4_RS09905 df7378b94485bdd322574a32732859d0 783 Pfam PF00702 haloacid dehalogenase-like hydrolase 464 687 8.0E-35 T 05-07-2017 K08M4_RS15245 947a00fa25587d171e0a887b7159d041 421 Gene3D G3DSA:3.90.1150.10 315 410 1.4E-25 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS15245 947a00fa25587d171e0a887b7159d041 421 Gene3D G3DSA:3.90.1150.10 3 54 1.4E-25 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS15245 947a00fa25587d171e0a887b7159d041 421 Pfam PF00202 Aminotransferase class-III 18 407 1.2E-79 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 K08M4_RS15245 947a00fa25587d171e0a887b7159d041 421 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 230 266 - T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 K08M4_RS15245 947a00fa25587d171e0a887b7159d041 421 SUPERFAMILY SSF53383 7 409 8.66E-102 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS15245 947a00fa25587d171e0a887b7159d041 421 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 2 412 8.5E-147 T 05-07-2017 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 K08M4_RS15245 947a00fa25587d171e0a887b7159d041 421 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 2 410 7.2E-202 T 05-07-2017 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 K08M4_RS15245 947a00fa25587d171e0a887b7159d041 421 Gene3D G3DSA:3.40.640.10 55 309 2.6E-63 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 Pfam PF00873 AcrB/AcrD/AcrF family 23 1031 4.5E-170 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 PRINTS PR00702 Acriflavin resistance protein family signature 29 53 5.3E-26 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 PRINTS PR00702 Acriflavin resistance protein family signature 57 75 5.3E-26 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 PRINTS PR00702 Acriflavin resistance protein family signature 405 429 5.3E-26 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 PRINTS PR00702 Acriflavin resistance protein family signature 483 506 5.3E-26 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 PRINTS PR00702 Acriflavin resistance protein family signature 351 374 5.3E-26 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 PRINTS PR00702 Acriflavin resistance protein family signature 458 481 5.3E-26 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 Gene3D G3DSA:1.10.3850.10 819 1032 3.8E-57 T 05-07-2017 K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 Gene3D G3DSA:1.20.1640.10 309 518 2.7E-40 T 05-07-2017 K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 SUPERFAMILY SSF82714 203 286 5.89E-12 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 SUPERFAMILY SSF82866 311 510 9.02E-34 T 05-07-2017 K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 SUPERFAMILY SSF82714 731 806 2.22E-8 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 SUPERFAMILY SSF82866 811 1033 8.63E-47 T 05-07-2017 K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 Gene3D G3DSA:3.30.2090.10 732 806 5.3E-6 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 Gene3D G3DSA:3.30.2090.10 203 286 5.5E-13 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 SUPERFAMILY SSF82693 59 154 4.19E-23 T 05-07-2017 K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 SUPERFAMILY SSF82693 289 344 1.23E-18 T 05-07-2017 K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 SUPERFAMILY SSF82693 155 201 1.23E-18 T 05-07-2017 K08M4_RS09310 80d22f73d99b8e5452bf4c2454c121de 1036 Gene3D G3DSA:3.30.70.1430 59 158 4.4E-28 T 05-07-2017 K08M4_RS01680 191d88c3b4a35337a257167d25516d44 206 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 30 202 38.735 T 05-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 K08M4_RS01680 191d88c3b4a35337a257167d25516d44 206 Pfam PF01583 Adenylylsulphate kinase 31 183 2.0E-71 T 05-07-2017 K08M4_RS01680 191d88c3b4a35337a257167d25516d44 206 SUPERFAMILY SSF52540 25 202 9.11E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01680 191d88c3b4a35337a257167d25516d44 206 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 14 198 1.1E-81 T 05-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 K08M4_RS01680 191d88c3b4a35337a257167d25516d44 206 Gene3D G3DSA:3.40.50.300 9 205 1.2E-89 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13905 ad662bfaed4fbdd18ce60e9e2506e914 212 Pfam PF13972 Bacterial transcriptional repressor 57 199 2.3E-41 T 05-07-2017 IPR025722 Bacterial transcriptional repressor TetR K08M4_RS13905 ad662bfaed4fbdd18ce60e9e2506e914 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 6.4E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS13905 ad662bfaed4fbdd18ce60e9e2506e914 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 6.4E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS13905 ad662bfaed4fbdd18ce60e9e2506e914 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 52 1.6E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS13905 ad662bfaed4fbdd18ce60e9e2506e914 212 SUPERFAMILY SSF46689 2 71 2.28E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS13905 ad662bfaed4fbdd18ce60e9e2506e914 212 Gene3D G3DSA:1.10.357.10 2 173 1.4E-28 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS15255 23a45a4623ea5f6400384caf25c6cc86 474 Pfam PF00696 Amino acid kinase family 4 293 6.3E-19 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS15255 23a45a4623ea5f6400384caf25c6cc86 474 Gene3D G3DSA:3.40.1160.10 3 49 3.7E-22 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS15255 23a45a4623ea5f6400384caf25c6cc86 474 Gene3D G3DSA:3.40.1160.10 126 307 3.7E-22 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS15255 23a45a4623ea5f6400384caf25c6cc86 474 SUPERFAMILY SSF55021 398 463 1.91E-8 T 05-07-2017 K08M4_RS15255 23a45a4623ea5f6400384caf25c6cc86 474 SUPERFAMILY SSF53633 5 307 1.94E-52 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS07660 b4b9606bdb6b9b7deb9b29ecfb01e9da 206 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 9 188 1.1E-80 T 05-07-2017 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO K08M4_RS07660 b4b9606bdb6b9b7deb9b29ecfb01e9da 206 Gene3D G3DSA:1.10.760.10 21 202 5.6E-34 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS07660 b4b9606bdb6b9b7deb9b29ecfb01e9da 206 SUPERFAMILY SSF46626 21 202 1.43E-27 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS07660 b4b9606bdb6b9b7deb9b29ecfb01e9da 206 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 9 186 5.3E-82 T 05-07-2017 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO K08M4_RS15105 03cf897e20d65bddb946825a13e67a70 496 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 436 1.6E-95 T 05-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 K08M4_RS15105 03cf897e20d65bddb946825a13e67a70 496 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 418 438 - T 05-07-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 K08M4_RS15105 03cf897e20d65bddb946825a13e67a70 496 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 6 490 1.0E-213 T 05-07-2017 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 K08M4_RS15105 03cf897e20d65bddb946825a13e67a70 496 Pfam PF00474 Sodium:solute symporter family 35 436 5.2E-106 T 05-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 K08M4_RS01845 ccdf657698c19e5c46a1ab62cabb083e 268 Gene3D G3DSA:3.40.50.300 4 237 5.5E-71 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01845 ccdf657698c19e5c46a1ab62cabb083e 268 SUPERFAMILY SSF52540 6 238 7.22E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01845 ccdf657698c19e5c46a1ab62cabb083e 268 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS01845 ccdf657698c19e5c46a1ab62cabb083e 268 SMART SM00382 31 237 5.2E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS01845 ccdf657698c19e5c46a1ab62cabb083e 268 Pfam PF00005 ABC transporter 23 170 4.3E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 Gene3D G3DSA:3.30.70.260 795 857 5.9E-9 T 05-07-2017 K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 Pfam PF01842 ACT domain 802 849 2.0E-6 T 05-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 SMART SM00471 447 594 4.5E-10 T 05-07-2017 IPR003607 HD/PDEase domain K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 28 868 0.0 T 05-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 Gene3D G3DSA:1.10.3210.10 421 610 4.6E-28 T 05-07-2017 IPR006674 HD domain K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 PIRSF PIRSF006288 8 873 0.0 T 05-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 SUPERFAMILY SSF55021 689 749 2.98E-7 T 05-07-2017 K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 Pfam PF08335 GlnD PII-uridylyltransferase 176 314 7.2E-36 T 05-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 SUPERFAMILY SSF109604 418 547 4.39E-15 T 05-07-2017 K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 SUPERFAMILY SSF81593 189 310 1.49E-9 T 05-07-2017 K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 873 335.849 T 05-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 SUPERFAMILY SSF55021 796 861 4.2E-10 T 05-07-2017 K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 Pfam PF01966 HD domain 451 584 1.4E-13 T 05-07-2017 IPR006674 HD domain K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 Pfam PF01909 Nucleotidyltransferase domain 69 100 2.5E-6 T 05-07-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 SUPERFAMILY SSF81301 34 169 3.54E-18 T 05-07-2017 K08M4_RS11240 3e9b923a807d40d6aa66bf2b0fb86485 873 Gene3D G3DSA:3.30.460.10 70 162 3.2E-8 T 05-07-2017 K08M4_RS04980 7e636f5837fc6cf5551e47adf1ae32e1 827 Gene3D G3DSA:3.20.20.450 568 819 1.3E-84 T 05-07-2017 IPR001633 EAL domain K08M4_RS04980 7e636f5837fc6cf5551e47adf1ae32e1 827 SMART SM00267 383 555 2.7E-52 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS04980 7e636f5837fc6cf5551e47adf1ae32e1 827 Gene3D G3DSA:3.30.450.20 65 219 9.2E-34 T 05-07-2017 K08M4_RS04980 7e636f5837fc6cf5551e47adf1ae32e1 827 SUPERFAMILY SSF141868 570 820 3.4E-81 T 05-07-2017 IPR001633 EAL domain K08M4_RS04980 7e636f5837fc6cf5551e47adf1ae32e1 827 Pfam PF00990 Diguanylate cyclase, GGDEF domain 394 548 1.4E-42 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS04980 7e636f5837fc6cf5551e47adf1ae32e1 827 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 392 552 4.8E-40 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS04980 7e636f5837fc6cf5551e47adf1ae32e1 827 Pfam PF00563 EAL domain 571 806 1.9E-70 T 05-07-2017 IPR001633 EAL domain K08M4_RS04980 7e636f5837fc6cf5551e47adf1ae32e1 827 Gene3D G3DSA:3.30.70.270 395 561 2.1E-49 T 05-07-2017 K08M4_RS04980 7e636f5837fc6cf5551e47adf1ae32e1 827 SUPERFAMILY SSF55073 399 557 6.28E-42 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS04980 7e636f5837fc6cf5551e47adf1ae32e1 827 SMART SM01049 72 165 3.9E-13 T 05-07-2017 IPR033480 Single Cache domain 2 K08M4_RS04980 7e636f5837fc6cf5551e47adf1ae32e1 827 Gene3D G3DSA:3.30.450.20 229 322 4.7E-7 T 05-07-2017 K08M4_RS04980 7e636f5837fc6cf5551e47adf1ae32e1 827 SMART SM00052 565 811 7.6E-99 T 05-07-2017 IPR001633 EAL domain K08M4_RS04980 7e636f5837fc6cf5551e47adf1ae32e1 827 Pfam PF08269 Cache domain 38 322 1.5E-72 T 05-07-2017 IPR004010 Double Cache domain 2 K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 492 652 2.6E-36 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 SMART SM00028 191 224 310.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 SMART SM00028 267 300 0.06 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 SMART SM00028 347 380 50.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 SMART SM00028 228 261 1.7 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 SMART SM00028 307 340 15.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 Pfam PF13181 Tetratricopeptide repeat 230 259 0.024 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 SMART SM00267 483 655 4.9E-38 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 Pfam PF00990 Diguanylate cyclase, GGDEF domain 494 650 7.7E-34 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 Gene3D G3DSA:1.25.40.10 282 323 5.0E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 SUPERFAMILY SSF48452 230 414 1.08E-20 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 Gene3D G3DSA:1.25.40.10 324 417 1.0E-11 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 SUPERFAMILY SSF55073 499 653 1.33E-33 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 Pfam PF13424 Tetratricopeptide repeat 267 336 2.5E-9 T 05-07-2017 K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 Pfam PF13424 Tetratricopeptide repeat 364 412 2.1E-7 T 05-07-2017 K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 Gene3D G3DSA:1.25.40.10 194 281 1.8E-10 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS07965 ab7f43179689b77a75ec47a92841d999 662 Gene3D G3DSA:3.30.70.270 496 652 2.3E-37 T 05-07-2017 K08M4_RS18255 77a991d540c7e456f9b4018e90fe4622 392 Gene3D G3DSA:1.25.40.10 120 227 3.3E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS18255 77a991d540c7e456f9b4018e90fe4622 392 SUPERFAMILY SSF48452 59 150 5.52E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS18255 77a991d540c7e456f9b4018e90fe4622 392 SUPERFAMILY SSF48452 186 226 5.52E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS18255 77a991d540c7e456f9b4018e90fe4622 392 Gene3D G3DSA:1.25.40.10 26 119 3.6E-4 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS18255 77a991d540c7e456f9b4018e90fe4622 392 SUPERFAMILY SSF48452 265 373 4.61E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS18255 77a991d540c7e456f9b4018e90fe4622 392 Gene3D G3DSA:1.25.40.10 271 370 2.4E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS18100 77a991d540c7e456f9b4018e90fe4622 392 Gene3D G3DSA:1.25.40.10 120 227 3.3E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS18100 77a991d540c7e456f9b4018e90fe4622 392 SUPERFAMILY SSF48452 59 150 5.52E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS18100 77a991d540c7e456f9b4018e90fe4622 392 SUPERFAMILY SSF48452 186 226 5.52E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS18100 77a991d540c7e456f9b4018e90fe4622 392 Gene3D G3DSA:1.25.40.10 26 119 3.6E-4 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS18100 77a991d540c7e456f9b4018e90fe4622 392 SUPERFAMILY SSF48452 265 373 4.61E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS18100 77a991d540c7e456f9b4018e90fe4622 392 Gene3D G3DSA:1.25.40.10 271 370 2.4E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS10925 3bd90b53941ba0a24d04f8e08fde36ca 377 SUPERFAMILY SSF64518 1 376 3.27E-95 T 05-07-2017 K08M4_RS10925 3bd90b53941ba0a24d04f8e08fde36ca 377 Pfam PF07196 Flagellin hook IN motif 209 245 1.0E-8 T 05-07-2017 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 K08M4_RS10925 3bd90b53941ba0a24d04f8e08fde36ca 377 PRINTS PR00207 Flagellin signature 37 54 2.4E-27 T 05-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 K08M4_RS10925 3bd90b53941ba0a24d04f8e08fde36ca 377 PRINTS PR00207 Flagellin signature 111 134 2.4E-27 T 05-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 K08M4_RS10925 3bd90b53941ba0a24d04f8e08fde36ca 377 PRINTS PR00207 Flagellin signature 76 95 2.4E-27 T 05-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 K08M4_RS10925 3bd90b53941ba0a24d04f8e08fde36ca 377 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 4.7E-43 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS10925 3bd90b53941ba0a24d04f8e08fde36ca 377 Gene3D G3DSA:1.20.1330.10 279 332 7.6E-62 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS10925 3bd90b53941ba0a24d04f8e08fde36ca 377 Gene3D G3DSA:1.20.1330.10 55 171 7.6E-62 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS10925 3bd90b53941ba0a24d04f8e08fde36ca 377 Pfam PF00700 Bacterial flagellin C-terminal helical region 292 376 8.8E-24 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 Pfam PF05524 PEP-utilising enzyme, N-terminal 173 295 2.2E-23 T 05-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 630 645 2.7E-23 T 05-07-2017 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 460 479 2.7E-23 T 05-07-2017 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 666 678 2.7E-23 T 05-07-2017 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 613 628 2.7E-23 T 05-07-2017 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 Gene3D G3DSA:1.10.274.10 197 302 4.5E-32 T 05-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 613 631 - T 05-07-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 Gene3D G3DSA:3.30.450.40 1 159 6.8E-42 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 Gene3D G3DSA:3.50.30.10 303 415 2.3E-28 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 173 728 1.6E-133 T 05-07-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 SUPERFAMILY SSF47831 199 312 4.84E-27 T 05-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 SUPERFAMILY SSF55781 2 158 3.49E-30 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 352 363 - T 05-07-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 Gene3D G3DSA:3.20.20.60 426 737 1.6E-97 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 SUPERFAMILY SSF51621 424 715 2.22E-94 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 SUPERFAMILY SSF52009 294 411 1.83E-26 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 Pfam PF01590 GAF domain 17 152 5.3E-14 T 05-07-2017 IPR003018 GAF domain GO:0005515 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 425 707 4.9E-94 T 05-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 Pfam PF00391 PEP-utilising enzyme, mobile domain 320 392 3.2E-15 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 K08M4_RS12290 5e9e440f4fe6b95d761357c798e050f8 749 SMART SM00065 17 163 7.3E-21 T 05-07-2017 IPR003018 GAF domain GO:0005515 K08M4_RS11135 5f5453407645853feda645a5a07d0b95 103 Gene3D G3DSA:1.10.760.10 18 103 1.1E-27 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS11135 5f5453407645853feda645a5a07d0b95 103 SUPERFAMILY SSF46626 18 102 2.33E-23 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS11135 5f5453407645853feda645a5a07d0b95 103 PRINTS PR00605 Class IC cytochrome C signature 32 43 3.1E-5 T 05-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 K08M4_RS11135 5f5453407645853feda645a5a07d0b95 103 PRINTS PR00605 Class IC cytochrome C signature 77 99 3.1E-5 T 05-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 K08M4_RS11135 5f5453407645853feda645a5a07d0b95 103 Pfam PF00034 Cytochrome c 32 103 6.1E-10 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS14360 b658f2ca9cc43dceb44eb949bc099fdf 219 SUPERFAMILY SSF52540 6 197 3.75E-33 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14360 b658f2ca9cc43dceb44eb949bc099fdf 219 Gene3D G3DSA:3.40.50.300 7 198 1.4E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14360 b658f2ca9cc43dceb44eb949bc099fdf 219 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 11 194 6.1E-73 T 05-07-2017 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 K08M4_RS14360 b658f2ca9cc43dceb44eb949bc099fdf 219 Pfam PF01926 50S ribosome-binding GTPase 29 147 1.1E-19 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS14360 b658f2ca9cc43dceb44eb949bc099fdf 219 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 15 198 27.471 T 05-07-2017 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 K08M4_RS11635 88954816ab97baed03ed414f860eec90 522 SUPERFAMILY SSF53955 270 422 2.73E-36 T 05-07-2017 IPR023346 Lysozyme-like domain K08M4_RS11635 88954816ab97baed03ed414f860eec90 522 SUPERFAMILY SSF53955 457 475 2.73E-36 T 05-07-2017 IPR023346 Lysozyme-like domain K08M4_RS11635 88954816ab97baed03ed414f860eec90 522 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 334 362 - T 05-07-2017 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 K08M4_RS11635 88954816ab97baed03ed414f860eec90 522 Gene3D G3DSA:3.40.190.10 20 146 5.4E-19 T 05-07-2017 K08M4_RS11635 88954816ab97baed03ed414f860eec90 522 Pfam PF01464 Transglycosylase SLT domain 323 426 6.2E-20 T 05-07-2017 IPR008258 Transglycosylase SLT domain 1 K08M4_RS11635 88954816ab97baed03ed414f860eec90 522 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 292 1.9E-26 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS11635 88954816ab97baed03ed414f860eec90 522 Gene3D G3DSA:1.10.530.10 313 483 6.2E-37 T 05-07-2017 K08M4_RS11635 88954816ab97baed03ed414f860eec90 522 SUPERFAMILY SSF53850 44 292 1.17E-32 T 05-07-2017 K08M4_RS11635 88954816ab97baed03ed414f860eec90 522 Hamap MF_02016 Membrane-bound lytic murein transglycosylase F [mltF]. 3 493 47.885 T 05-07-2017 IPR023703 Membrane-bound lytic murein transglycosylase F GO:0016837 K08M4_RS11635 88954816ab97baed03ed414f860eec90 522 SMART SM00062 43 293 9.1E-20 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS16880 36803536effa60fa58303e5f529e093b 272 Gene3D G3DSA:3.40.50.1000 106 260 8.5E-31 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS16880 36803536effa60fa58303e5f529e093b 272 Gene3D G3DSA:3.40.50.1000 5 25 8.5E-31 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS16880 36803536effa60fa58303e5f529e093b 272 TIGRFAM TIGR01422 phosphonatase: phosphonoacetaldehyde hydrolase 7 260 2.9E-112 T 05-07-2017 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 K08M4_RS16880 36803536effa60fa58303e5f529e093b 272 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 69 206 1.9E-13 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS16880 36803536effa60fa58303e5f529e093b 272 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 206 2.1E-8 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS16880 36803536effa60fa58303e5f529e093b 272 Gene3D G3DSA:1.10.150.240 26 103 3.4E-33 T 05-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 K08M4_RS16880 36803536effa60fa58303e5f529e093b 272 Hamap MF_01375 Phosphonoacetaldehyde hydrolase [phnX]. 1 272 137.492 T 05-07-2017 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 K08M4_RS16880 36803536effa60fa58303e5f529e093b 272 SUPERFAMILY SSF56784 7 262 1.78E-49 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS12795 55cebdd90cd068330e74024e5d5be914 160 Gene3D G3DSA:3.30.70.560 3 149 5.4E-36 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS12795 55cebdd90cd068330e74024e5d5be914 160 SUPERFAMILY SSF55083 1 149 5.23E-37 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS12795 55cebdd90cd068330e74024e5d5be914 160 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 129 7.0E-23 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS12795 55cebdd90cd068330e74024e5d5be914 160 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 129 1.5E-28 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS15110 90a5c090a040319942652bb7d5ddfe6b 234 Gene3D G3DSA:3.40.605.10 44 178 8.4E-8 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS15110 90a5c090a040319942652bb7d5ddfe6b 234 SUPERFAMILY SSF53720 11 180 2.36E-10 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 TIGRFAM TIGR02813 omega_3_PfaA: polyketide-type polyunsaturated fatty acid synthase PfaA 18 2608 0.0 T 05-07-2017 IPR004432 Polyketide-type polyunsaturated fatty acid synthase, PfaA K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Gene3D G3DSA:3.30.70.250 735 800 4.7E-15 T 05-07-2017 K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Gene3D G3DSA:3.40.366.10 591 727 1.4E-59 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Gene3D G3DSA:3.40.366.10 801 899 1.4E-59 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SUPERFAMILY SSF55048 735 801 1.2E-12 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SUPERFAMILY SSF47336 1453 1552 3.14E-16 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 309 426 3.5E-38 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SUPERFAMILY SSF51735 1791 1986 5.34E-5 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Gene3D G3DSA:3.40.47.10 26 313 1.6E-62 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SUPERFAMILY SSF47336 1351 1442 3.01E-17 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SUPERFAMILY SSF53901 25 145 4.55E-55 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SUPERFAMILY SSF53901 190 308 4.55E-55 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Pfam PF00698 Acyl transferase domain 599 899 7.1E-34 T 05-07-2017 IPR014043 Acyl transferase K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SMART SM00825 Beta-ketoacyl synthase 26 481 1.5E-87 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Gene3D G3DSA:3.40.50.720 2118 2284 4.6E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Gene3D G3DSA:3.40.50.720 2032 2070 4.6E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SUPERFAMILY SSF51735 2115 2288 5.94E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SUPERFAMILY SSF51735 2030 2071 5.94E-29 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Gene3D G3DSA:3.40.47.10 314 482 1.6E-54 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SUPERFAMILY SSF53901 271 479 1.38E-62 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Pfam PF00550 Phosphopantetheine attachment site 1565 1631 4.3E-10 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Pfam PF00550 Phosphopantetheine attachment site 1459 1525 2.1E-10 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Pfam PF00550 Phosphopantetheine attachment site 1357 1424 6.7E-11 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Pfam PF00550 Phosphopantetheine attachment site 1248 1314 1.8E-9 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Pfam PF00550 Phosphopantetheine attachment site 1672 1737 1.2E-9 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Pfam PF14765 Polyketide synthase dehydratase 2321 2599 5.6E-30 T 05-07-2017 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 24 301 2.9E-74 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 429 534 4.3E-15 T 05-07-2017 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SUPERFAMILY SSF47336 1243 1335 5.63E-16 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SUPERFAMILY SSF47336 1665 1756 3.66E-16 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 599 910 3.0E-42 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SUPERFAMILY SSF47336 1557 1650 4.58E-16 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Gene3D G3DSA:1.10.1200.10 1663 1742 5.8E-19 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Gene3D G3DSA:1.10.1200.10 1350 1429 4.0E-20 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Gene3D G3DSA:1.10.1200.10 1556 1636 2.4E-19 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Gene3D G3DSA:1.10.1200.10 1242 1318 2.0E-18 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Gene3D G3DSA:1.10.1200.10 1452 1529 1.5E-18 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 Pfam PF08659 KR domain 2032 2252 6.7E-30 T 05-07-2017 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2030 2254 4.6E-39 T 05-07-2017 K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SUPERFAMILY SSF52151 802 898 2.49E-58 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 K08M4_RS10440 3ec46a7566d707be05b887b5163b8beb 2630 SUPERFAMILY SSF52151 595 733 2.49E-58 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 K08M4_RS10985 49101a91df9a68858629d0cc013587c7 378 Gene3D G3DSA:3.30.70.360 190 290 2.0E-30 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS10985 49101a91df9a68858629d0cc013587c7 378 SUPERFAMILY SSF53187 6 180 4.98E-64 T 05-07-2017 K08M4_RS10985 49101a91df9a68858629d0cc013587c7 378 SUPERFAMILY SSF53187 294 375 4.98E-64 T 05-07-2017 K08M4_RS10985 49101a91df9a68858629d0cc013587c7 378 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 99 137 - T 05-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 K08M4_RS10985 49101a91df9a68858629d0cc013587c7 378 SUPERFAMILY SSF55031 181 291 5.23E-27 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS10985 49101a91df9a68858629d0cc013587c7 378 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 7 375 1.6E-173 T 05-07-2017 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 K08M4_RS10985 49101a91df9a68858629d0cc013587c7 378 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 4 377 51.312 T 05-07-2017 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 K08M4_RS10985 49101a91df9a68858629d0cc013587c7 378 Gene3D G3DSA:3.40.630.10 5 189 9.8E-72 T 05-07-2017 K08M4_RS10985 49101a91df9a68858629d0cc013587c7 378 Gene3D G3DSA:3.40.630.10 318 376 9.8E-72 T 05-07-2017 K08M4_RS10985 49101a91df9a68858629d0cc013587c7 378 Pfam PF07687 Peptidase dimerisation domain 177 284 5.2E-20 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS10985 49101a91df9a68858629d0cc013587c7 378 Pfam PF01546 Peptidase family M20/M25/M40 64 373 1.9E-44 T 05-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 K08M4_RS00925 4ddcf1880dac25fa7de428d64b4453f5 150 Gene3D G3DSA:2.40.50.100 74 150 3.8E-32 T 05-07-2017 K08M4_RS00925 4ddcf1880dac25fa7de428d64b4453f5 150 Pfam PF00364 Biotin-requiring enzyme 75 149 5.2E-24 T 05-07-2017 IPR000089 Biotin/lipoyl attachment K08M4_RS00925 4ddcf1880dac25fa7de428d64b4453f5 150 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 150 9.8E-61 T 05-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 K08M4_RS00925 4ddcf1880dac25fa7de428d64b4453f5 150 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 106 123 - T 05-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 K08M4_RS00925 4ddcf1880dac25fa7de428d64b4453f5 150 SUPERFAMILY SSF51230 75 150 8.77E-26 T 05-07-2017 IPR011053 Single hybrid motif K08M4_RS00925 4ddcf1880dac25fa7de428d64b4453f5 150 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 96 110 1.1E-17 T 05-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 K08M4_RS00925 4ddcf1880dac25fa7de428d64b4453f5 150 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 79 92 1.1E-17 T 05-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 K08M4_RS00925 4ddcf1880dac25fa7de428d64b4453f5 150 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 111 124 1.1E-17 T 05-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 K08M4_RS11905 6cd90bacfc4e00ede5116d105041ad95 173 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 134 1.4E-64 T 05-07-2017 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 K08M4_RS11905 6cd90bacfc4e00ede5116d105041ad95 173 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 05-07-2017 IPR030489 Transcription regulator Rrf2-type, conserved site K08M4_RS11905 6cd90bacfc4e00ede5116d105041ad95 173 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 2.2E-46 T 05-07-2017 IPR000944 Transcription regulator Rrf2-type K08M4_RS11905 6cd90bacfc4e00ede5116d105041ad95 173 Hamap MF_01176 HTH-type transcriptional regulator IscR [iscR]. 1 173 49.565 T 05-07-2017 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 K08M4_RS11905 6cd90bacfc4e00ede5116d105041ad95 173 SUPERFAMILY SSF46785 2 133 9.1E-36 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS11905 6cd90bacfc4e00ede5116d105041ad95 173 Pfam PF02082 Transcriptional regulator 1 83 1.4E-27 T 05-07-2017 IPR000944 Transcription regulator Rrf2-type K08M4_RS11905 6cd90bacfc4e00ede5116d105041ad95 173 Gene3D G3DSA:1.10.10.10 1 134 2.1E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS08880 f17a3477f81200d38e2c05e1c76ce577 457 PRINTS PR00385 P450 superfamily signature 404 415 1.8E-12 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 K08M4_RS08880 f17a3477f81200d38e2c05e1c76ce577 457 PRINTS PR00385 P450 superfamily signature 322 333 1.8E-12 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 K08M4_RS08880 f17a3477f81200d38e2c05e1c76ce577 457 PRINTS PR00385 P450 superfamily signature 395 404 1.8E-12 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 K08M4_RS08880 f17a3477f81200d38e2c05e1c76ce577 457 PRINTS PR00385 P450 superfamily signature 271 288 1.8E-12 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 K08M4_RS08880 f17a3477f81200d38e2c05e1c76ce577 457 SUPERFAMILY SSF48264 8 456 1.83E-94 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 K08M4_RS08880 f17a3477f81200d38e2c05e1c76ce577 457 Gene3D G3DSA:1.10.630.10 3 457 8.2E-106 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 K08M4_RS08880 f17a3477f81200d38e2c05e1c76ce577 457 PRINTS PR00463 E-class P450 group I signature 321 339 4.3E-25 T 05-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 K08M4_RS08880 f17a3477f81200d38e2c05e1c76ce577 457 PRINTS PR00463 E-class P450 group I signature 260 277 4.3E-25 T 05-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 K08M4_RS08880 f17a3477f81200d38e2c05e1c76ce577 457 PRINTS PR00463 E-class P450 group I signature 404 427 4.3E-25 T 05-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 K08M4_RS08880 f17a3477f81200d38e2c05e1c76ce577 457 PRINTS PR00463 E-class P450 group I signature 394 404 4.3E-25 T 05-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 K08M4_RS08880 f17a3477f81200d38e2c05e1c76ce577 457 PRINTS PR00463 E-class P450 group I signature 35 54 4.3E-25 T 05-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 K08M4_RS08880 f17a3477f81200d38e2c05e1c76ce577 457 PRINTS PR00463 E-class P450 group I signature 150 168 4.3E-25 T 05-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 K08M4_RS08880 f17a3477f81200d38e2c05e1c76ce577 457 PRINTS PR00463 E-class P450 group I signature 361 385 4.3E-25 T 05-07-2017 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 K08M4_RS08880 f17a3477f81200d38e2c05e1c76ce577 457 Pfam PF00067 Cytochrome P450 12 452 3.2E-76 T 05-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 K08M4_RS08880 f17a3477f81200d38e2c05e1c76ce577 457 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 397 406 - T 05-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 Gene3D G3DSA:3.30.450.20 869 928 2.8E-7 T 05-07-2017 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 Pfam PF00672 HAMP domain 358 427 7.9E-16 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 Gene3D G3DSA:1.10.287.130 451 512 1.2E-15 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 SMART SM00304 377 430 8.3E-12 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 PRINTS PR00344 Bacterial sensor protein C-terminal signature 668 681 2.5E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 PRINTS PR00344 Bacterial sensor protein C-terminal signature 644 662 2.5E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 PRINTS PR00344 Bacterial sensor protein C-terminal signature 627 637 2.5E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 PRINTS PR00344 Bacterial sensor protein C-terminal signature 609 623 2.5E-15 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 Pfam PF00072 Response regulator receiver domain 726 836 2.1E-31 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 SUPERFAMILY SSF52172 720 848 1.57E-40 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 Gene3D G3DSA:3.30.450.20 233 353 9.8E-4 T 05-07-2017 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 Gene3D G3DSA:3.30.565.10 513 686 1.3E-43 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 SUPERFAMILY SSF55785 862 932 3.05E-6 T 05-07-2017 IPR000014 PAS domain K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 SMART SM00091 874 939 0.0016 T 05-07-2017 IPR000014 PAS domain K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 Pfam PF00512 His Kinase A (phospho-acceptor) domain 460 525 1.3E-14 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 SMART SM00388 459 527 8.7E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 574 683 2.1E-27 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 SUPERFAMILY SSF47384 445 527 4.9E-19 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 SMART SM00387 573 684 4.4E-37 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 SUPERFAMILY SSF55874 516 688 4.71E-45 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 SUPERFAMILY SSF158472 378 427 9.68E-11 T 05-07-2017 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 SMART SM00448 723 836 2.6E-43 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 Gene3D G3DSA:3.40.50.2300 723 848 1.1E-41 T 05-07-2017 K08M4_RS03005 50e2db98d9076217456457ac044b6227 1129 Pfam PF13188 PAS domain 880 916 1.6E-4 T 05-07-2017 IPR000014 PAS domain K08M4_RS15120 2cf9eaed3b8bbda7c8a9d11ba17d2db4 275 Pfam PF12833 Helix-turn-helix domain 191 269 2.5E-18 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS15120 2cf9eaed3b8bbda7c8a9d11ba17d2db4 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 237 252 8.8E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS15120 2cf9eaed3b8bbda7c8a9d11ba17d2db4 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 252 268 8.8E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS15120 2cf9eaed3b8bbda7c8a9d11ba17d2db4 275 Gene3D G3DSA:2.60.120.10 33 93 8.9E-6 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS15120 2cf9eaed3b8bbda7c8a9d11ba17d2db4 275 Gene3D G3DSA:1.10.10.60 172 221 1.6E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS15120 2cf9eaed3b8bbda7c8a9d11ba17d2db4 275 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 222 264 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 K08M4_RS15120 2cf9eaed3b8bbda7c8a9d11ba17d2db4 275 SUPERFAMILY SSF51182 29 95 6.23E-5 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS15120 2cf9eaed3b8bbda7c8a9d11ba17d2db4 275 Gene3D G3DSA:1.10.10.60 222 271 4.6E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS15120 2cf9eaed3b8bbda7c8a9d11ba17d2db4 275 SMART SM00342 185 268 2.1E-24 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS15120 2cf9eaed3b8bbda7c8a9d11ba17d2db4 275 SUPERFAMILY SSF46689 222 271 5.38E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS15120 2cf9eaed3b8bbda7c8a9d11ba17d2db4 275 SUPERFAMILY SSF46689 172 218 7.62E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Gene3D G3DSA:3.90.1110.10 346 444 4.6E-65 T 05-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Gene3D G3DSA:3.90.1110.10 153 230 4.6E-65 T 05-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Gene3D G3DSA:2.40.270.10 793 820 5.8E-85 T 05-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Gene3D G3DSA:2.40.270.10 1060 1241 5.8E-85 T 05-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 SUPERFAMILY SSF64484 343 939 0.0 T 05-07-2017 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 SUPERFAMILY SSF64484 11 226 0.0 T 05-07-2017 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 SUPERFAMILY SSF64484 1039 1341 0.0 T 05-07-2017 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Pfam PF04561 RNA polymerase Rpb2, domain 2 338 454 2.8E-17 T 05-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Pfam PF04561 RNA polymerase Rpb2, domain 2 151 225 7.2E-8 T 05-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Pfam PF04560 RNA polymerase Rpb2, domain 7 1265 1339 2.9E-27 T 05-07-2017 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Gene3D G3DSA:2.40.50.100 715 792 7.4E-30 T 05-07-2017 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Pfam PF04563 RNA polymerase beta subunit 26 500 2.7E-57 T 05-07-2017 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Gene3D G3DSA:2.40.50.150 828 937 1.4E-57 T 05-07-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Gene3D G3DSA:2.40.50.150 1045 1059 1.4E-57 T 05-07-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Gene3D G3DSA:3.90.1100.10 659 713 6.5E-145 T 05-07-2017 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Gene3D G3DSA:3.90.1100.10 445 591 6.5E-145 T 05-07-2017 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Gene3D G3DSA:3.90.1100.10 20 151 6.5E-145 T 05-07-2017 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Pfam PF10385 RNA polymerase beta subunit external 1 domain 591 656 3.0E-22 T 05-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1063 1075 - T 05-07-2017 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Pfam PF04565 RNA polymerase Rpb2, domain 3 513 580 1.1E-28 T 05-07-2017 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Gene3D G3DSA:2.30.150.10 592 656 1.3E-26 T 05-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1341 12.308 T 05-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 Pfam PF00562 RNA polymerase Rpb2, domain 6 717 1263 5.9E-156 T 05-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00830 62ab1c87cd8c9779c6c7b08f34fd1fc3 1342 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1338 0.0 T 05-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS10970 51ab9f7734219010c72cb5c0f7c4addc 301 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 286 4.6E-85 T 05-07-2017 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 K08M4_RS10970 51ab9f7734219010c72cb5c0f7c4addc 301 SUPERFAMILY SSF56059 98 288 7.81E-50 T 05-07-2017 K08M4_RS10970 51ab9f7734219010c72cb5c0f7c4addc 301 Pfam PF08443 RimK-like ATP-grasp domain 98 286 1.2E-67 T 05-07-2017 IPR013651 ATP-grasp fold, RimK-type K08M4_RS10970 51ab9f7734219010c72cb5c0f7c4addc 301 Hamap MF_01552 Ribosomal protein S6--L-glutamate ligase [rimK]. 1 295 51.262 T 05-07-2017 IPR023533 Ribosomal protein S6--L-glutamate ligase RimK K08M4_RS10970 51ab9f7734219010c72cb5c0f7c4addc 301 Gene3D G3DSA:3.30.1490.20 103 171 3.5E-7 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 K08M4_RS10970 51ab9f7734219010c72cb5c0f7c4addc 301 Gene3D G3DSA:3.40.50.20 8 102 8.1E-16 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS10970 51ab9f7734219010c72cb5c0f7c4addc 301 Gene3D G3DSA:3.30.470.20 172 277 5.8E-37 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS02230 405b94fbc0aa1fc0d8b217d75ecdda96 279 SUPERFAMILY SSF53790 1 249 9.95E-57 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS02230 405b94fbc0aa1fc0d8b217d75ecdda96 279 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 4 245 5.8E-94 T 05-07-2017 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 K08M4_RS02230 405b94fbc0aa1fc0d8b217d75ecdda96 279 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 213 3.0E-41 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS02230 405b94fbc0aa1fc0d8b217d75ecdda96 279 Gene3D G3DSA:3.30.950.10 118 231 3.9E-15 T 05-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS02230 405b94fbc0aa1fc0d8b217d75ecdda96 279 Gene3D G3DSA:3.40.1010.10 2 117 5.0E-30 T 05-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS14205 d54376006096cb77049700b53ad4dc37 415 PIRSF PIRSF015761 15 414 2.8E-31 T 05-07-2017 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 K08M4_RS14205 d54376006096cb77049700b53ad4dc37 415 SUPERFAMILY SSF53067 146 249 4.99E-18 T 05-07-2017 K08M4_RS14205 d54376006096cb77049700b53ad4dc37 415 Pfam PF12693 GspL periplasmic domain 255 413 8.4E-49 T 05-07-2017 IPR025691 GspL periplasmic domain K08M4_RS14205 d54376006096cb77049700b53ad4dc37 415 Pfam PF05134 Type II secretion system (T2SS), protein L 5 250 1.0E-61 T 05-07-2017 IPR024230 GspL, cytoplasmic actin-ATPase-like domain K08M4_RS14205 d54376006096cb77049700b53ad4dc37 415 TIGRFAM TIGR01709 typeII_sec_gspL: type II secretion system protein L 5 413 4.5E-84 T 05-07-2017 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 K08M4_RS14205 d54376006096cb77049700b53ad4dc37 415 SUPERFAMILY SSF53067 2 144 4.27E-39 T 05-07-2017 K08M4_RS11355 7dd38151a20c60cd657c9424cb8cd457 561 Gene3D G3DSA:3.20.20.80 180 479 8.2E-127 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS11355 7dd38151a20c60cd657c9424cb8cd457 561 Gene3D G3DSA:3.20.20.80 9 109 8.2E-127 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS11355 7dd38151a20c60cd657c9424cb8cd457 561 Pfam PF00128 Alpha amylase, catalytic domain 33 375 1.0E-126 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS11355 7dd38151a20c60cd657c9424cb8cd457 561 SUPERFAMILY SSF51011 480 559 5.76E-16 T 05-07-2017 K08M4_RS11355 7dd38151a20c60cd657c9424cb8cd457 561 Pfam PF16657 Maltogenic Amylase, C-terminal domain 480 554 3.1E-8 T 05-07-2017 IPR032091 Maltogenic Amylase, C-terminal K08M4_RS11355 7dd38151a20c60cd657c9424cb8cd457 561 SUPERFAMILY SSF51445 9 477 3.05E-160 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS11355 7dd38151a20c60cd657c9424cb8cd457 561 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 10 557 7.5E-266 T 05-07-2017 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 K08M4_RS11355 7dd38151a20c60cd657c9424cb8cd457 561 SMART SM00642 18 419 7.1E-160 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS11355 7dd38151a20c60cd657c9424cb8cd457 561 Gene3D G3DSA:3.90.400.10 110 179 2.1E-31 T 05-07-2017 K08M4_RS11355 7dd38151a20c60cd657c9424cb8cd457 561 Gene3D G3DSA:2.60.40.1180 482 559 1.6E-19 T 05-07-2017 IPR013780 Glycosyl hydrolase, all-beta K08M4_RS16530 de669266c430839fc9f7ca47cce2ad0a 451 Gene3D G3DSA:3.30.70.270 295 449 2.7E-48 T 05-07-2017 K08M4_RS16530 de669266c430839fc9f7ca47cce2ad0a 451 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 292 448 1.2E-43 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS16530 de669266c430839fc9f7ca47cce2ad0a 451 Pfam PF00990 Diguanylate cyclase, GGDEF domain 295 449 2.4E-43 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS16530 de669266c430839fc9f7ca47cce2ad0a 451 SMART SM01079 47 223 7.3E-30 T 05-07-2017 IPR006189 CHASE domain K08M4_RS16530 de669266c430839fc9f7ca47cce2ad0a 451 SMART SM00267 282 451 5.5E-43 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS16530 de669266c430839fc9f7ca47cce2ad0a 451 Pfam PF03924 CHASE domain 111 221 1.9E-14 T 05-07-2017 IPR006189 CHASE domain K08M4_RS16530 de669266c430839fc9f7ca47cce2ad0a 451 SUPERFAMILY SSF55073 299 449 2.9E-42 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS07580 b4a1fa5a78c81179aeb1309b6c2d6c3c 344 SUPERFAMILY SSF53850 27 332 8.15E-84 T 05-07-2017 K08M4_RS07580 b4a1fa5a78c81179aeb1309b6c2d6c3c 344 Gene3D G3DSA:3.40.190.10 145 298 1.3E-54 T 05-07-2017 K08M4_RS07580 b4a1fa5a78c81179aeb1309b6c2d6c3c 344 Pfam PF13416 Bacterial extracellular solute-binding protein 43 310 7.1E-36 T 05-07-2017 K08M4_RS07580 b4a1fa5a78c81179aeb1309b6c2d6c3c 344 PIRSF PIRSF019574 1 344 1.7E-107 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07580 b4a1fa5a78c81179aeb1309b6c2d6c3c 344 Gene3D G3DSA:3.40.190.10 28 144 2.8E-22 T 05-07-2017 K08M4_RS07580 b4a1fa5a78c81179aeb1309b6c2d6c3c 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 167 186 7.3E-66 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07580 b4a1fa5a78c81179aeb1309b6c2d6c3c 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 204 223 7.3E-66 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07580 b4a1fa5a78c81179aeb1309b6c2d6c3c 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 33 49 7.3E-66 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07580 b4a1fa5a78c81179aeb1309b6c2d6c3c 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 49 70 7.3E-66 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07580 b4a1fa5a78c81179aeb1309b6c2d6c3c 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 92 105 7.3E-66 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07580 b4a1fa5a78c81179aeb1309b6c2d6c3c 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 248 267 7.3E-66 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07580 b4a1fa5a78c81179aeb1309b6c2d6c3c 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 76 90 7.3E-66 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07580 b4a1fa5a78c81179aeb1309b6c2d6c3c 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 149 163 7.3E-66 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07580 b4a1fa5a78c81179aeb1309b6c2d6c3c 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 123 139 7.3E-66 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS12070 66bccb628635783afc8ae209c0b1eddd 193 Pfam PF13358 DDE superfamily endonuclease 23 161 1.0E-27 T 05-07-2017 K08M4_RS11340 66bccb628635783afc8ae209c0b1eddd 193 Pfam PF13358 DDE superfamily endonuclease 23 161 1.0E-27 T 05-07-2017 K08M4_RS07735 66bccb628635783afc8ae209c0b1eddd 193 Pfam PF13358 DDE superfamily endonuclease 23 161 1.0E-27 T 05-07-2017 K08M4_RS14685 66bccb628635783afc8ae209c0b1eddd 193 Pfam PF13358 DDE superfamily endonuclease 23 161 1.0E-27 T 05-07-2017 K08M4_RS00365 66bccb628635783afc8ae209c0b1eddd 193 Pfam PF13358 DDE superfamily endonuclease 23 161 1.0E-27 T 05-07-2017 K08M4_RS20635 66bccb628635783afc8ae209c0b1eddd 193 Pfam PF13358 DDE superfamily endonuclease 23 161 1.0E-27 T 05-07-2017 K08M4_RS18375 c06819e3f9a3018cc3b4d58605532a05 365 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 235 324 1.8E-32 T 05-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 K08M4_RS18375 c06819e3f9a3018cc3b4d58605532a05 365 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 184 5.6E-28 T 05-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 K08M4_RS18375 c06819e3f9a3018cc3b4d58605532a05 365 Gene3D G3DSA:3.40.47.10 163 324 1.3E-44 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS18375 c06819e3f9a3018cc3b4d58605532a05 365 Gene3D G3DSA:3.40.47.10 5 162 2.0E-63 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS18375 c06819e3f9a3018cc3b4d58605532a05 365 SUPERFAMILY SSF53901 7 324 4.36E-63 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS18375 c06819e3f9a3018cc3b4d58605532a05 365 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 4 324 63.562 T 05-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 K08M4_RS18375 c06819e3f9a3018cc3b4d58605532a05 365 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 5 324 2.0E-107 T 05-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 K08M4_RS20310 754a3bb2356144902588cd71f2667c36 398 SMART SM00490 257 338 9.2E-30 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS20310 754a3bb2356144902588cd71f2667c36 398 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 05-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site K08M4_RS20310 754a3bb2356144902588cd71f2667c36 398 Gene3D G3DSA:3.40.50.300 2 218 3.5E-78 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20310 754a3bb2356144902588cd71f2667c36 398 SMART SM00487 20 221 1.3E-61 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS20310 754a3bb2356144902588cd71f2667c36 398 Gene3D G3DSA:3.40.50.300 219 369 2.7E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20310 754a3bb2356144902588cd71f2667c36 398 Pfam PF00270 DEAD/DEAH box helicase 25 193 4.8E-50 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS20310 754a3bb2356144902588cd71f2667c36 398 SUPERFAMILY SSF52540 73 359 3.23E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20310 754a3bb2356144902588cd71f2667c36 398 Pfam PF00271 Helicase conserved C-terminal domain 238 337 9.9E-26 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS05090 b748b18b443e733ad78cbe244b4c78a6 193 Hamap MF_00528 Septum formation protein Maf [maf]. 5 192 29.531 T 05-07-2017 IPR003697 Maf-like protein GO:0005737 K08M4_RS05090 b748b18b443e733ad78cbe244b4c78a6 193 SUPERFAMILY SSF52972 2 186 1.5E-58 T 05-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like K08M4_RS05090 b748b18b443e733ad78cbe244b4c78a6 193 PIRSF PIRSF006305 1 192 7.5E-49 T 05-07-2017 IPR003697 Maf-like protein GO:0005737 K08M4_RS05090 b748b18b443e733ad78cbe244b4c78a6 193 Pfam PF02545 Maf-like protein 5 186 2.0E-46 T 05-07-2017 IPR003697 Maf-like protein GO:0005737 K08M4_RS05090 b748b18b443e733ad78cbe244b4c78a6 193 Gene3D G3DSA:3.90.950.10 4 191 5.6E-57 T 05-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like K08M4_RS05090 b748b18b443e733ad78cbe244b4c78a6 193 TIGRFAM TIGR00172 maf: septum formation protein Maf 4 185 4.5E-53 T 05-07-2017 IPR003697 Maf-like protein GO:0005737 K08M4_RS17815 bdb2de143f6579a236c80988259cddd9 399 SUPERFAMILY SSF109604 153 324 3.38E-30 T 05-07-2017 K08M4_RS17815 bdb2de143f6579a236c80988259cddd9 399 Pfam PF01966 HD domain 163 284 4.5E-14 T 05-07-2017 IPR006674 HD domain K08M4_RS17815 bdb2de143f6579a236c80988259cddd9 399 SMART SM00471 158 294 1.3E-8 T 05-07-2017 IPR003607 HD/PDEase domain K08M4_RS17815 bdb2de143f6579a236c80988259cddd9 399 Gene3D G3DSA:1.10.3210.10 158 294 1.4E-16 T 05-07-2017 IPR006674 HD domain K08M4_RS17815 bdb2de143f6579a236c80988259cddd9 399 Pfam PF11871 Domain of unknown function (DUF3391) 9 125 6.1E-17 T 05-07-2017 IPR021812 Protein of unknown function DUF3391 K08M4_RS17710 2413f05a4b117d0d179bb0182dafb1d5 197 PRINTS PR01021 OMPA domain signature 93 115 8.7E-8 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS17710 2413f05a4b117d0d179bb0182dafb1d5 197 PRINTS PR01021 OMPA domain signature 123 138 8.7E-8 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS17710 2413f05a4b117d0d179bb0182dafb1d5 197 PRINTS PR01021 OMPA domain signature 138 154 8.7E-8 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS17710 2413f05a4b117d0d179bb0182dafb1d5 197 SUPERFAMILY SSF103088 81 193 1.83E-29 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS17710 2413f05a4b117d0d179bb0182dafb1d5 197 Gene3D G3DSA:3.30.1330.60 81 194 4.8E-30 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS17710 2413f05a4b117d0d179bb0182dafb1d5 197 Pfam PF00691 OmpA family 92 187 1.2E-16 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS17710 2413f05a4b117d0d179bb0182dafb1d5 197 ProSitePatterns PS01068 OmpA-like domain. 125 169 - T 05-07-2017 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 K08M4_RS01430 84c49819d97e20710723a1a64bf06260 118 Gene3D G3DSA:3.40.1260.10 2 118 7.2E-46 T 05-07-2017 IPR027396 DsrEFH-like K08M4_RS01430 84c49819d97e20710723a1a64bf06260 118 SUPERFAMILY SSF75169 2 118 1.83E-37 T 05-07-2017 IPR027396 DsrEFH-like K08M4_RS01430 84c49819d97e20710723a1a64bf06260 118 Pfam PF02635 DsrE/DsrF-like family 3 118 4.7E-29 T 05-07-2017 IPR003787 Sulphur relay, DsrE/F-like protein K08M4_RS01430 84c49819d97e20710723a1a64bf06260 118 TIGRFAM TIGR03010 sulf_tusC_dsrF: sulfur relay protein TusC/DsrF 3 118 3.6E-46 T 05-07-2017 IPR017462 Sulphur relay, TusC/DsrF K08M4_RS20150 d8e91840eda01792d6ea482e600dc00e 138 Gene3D G3DSA:3.10.180.10 5 130 1.7E-19 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS20150 d8e91840eda01792d6ea482e600dc00e 138 SUPERFAMILY SSF54593 2 127 3.49E-23 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS20150 d8e91840eda01792d6ea482e600dc00e 138 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 105 1.2E-8 T 05-07-2017 K08M4_RS20935 79856d774a1624a5df0a30f06c87d04f 476 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 6.4E-16 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS20935 79856d774a1624a5df0a30f06c87d04f 476 SUPERFAMILY SSF46785 7 81 3.0E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20935 79856d774a1624a5df0a30f06c87d04f 476 Gene3D G3DSA:1.10.10.10 6 73 3.5E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20935 79856d774a1624a5df0a30f06c87d04f 476 Gene3D G3DSA:3.40.640.10 143 347 4.3E-53 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS20935 79856d774a1624a5df0a30f06c87d04f 476 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 5.8E-6 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS20935 79856d774a1624a5df0a30f06c87d04f 476 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 5.8E-6 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS20935 79856d774a1624a5df0a30f06c87d04f 476 SUPERFAMILY SSF53383 112 472 2.5E-69 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS20935 79856d774a1624a5df0a30f06c87d04f 476 SMART SM00345 13 72 1.1E-22 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS20935 79856d774a1624a5df0a30f06c87d04f 476 Pfam PF00155 Aminotransferase class I and II 147 456 1.5E-22 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS20935 79856d774a1624a5df0a30f06c87d04f 476 Gene3D G3DSA:3.90.1150.10 348 473 2.7E-5 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS01890 de40b62261b32a7c43e0ef3778227b30 153 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 7 97 5.4E-30 T 05-07-2017 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal K08M4_RS01890 de40b62261b32a7c43e0ef3778227b30 153 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 4 152 33.993 T 05-07-2017 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 K08M4_RS01890 de40b62261b32a7c43e0ef3778227b30 153 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 5 150 9.9E-61 T 05-07-2017 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 K08M4_RS01890 de40b62261b32a7c43e0ef3778227b30 153 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 102 150 9.2E-19 T 05-07-2017 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal K08M4_RS01890 de40b62261b32a7c43e0ef3778227b30 153 SUPERFAMILY SSF57825 101 151 3.66E-16 T 05-07-2017 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal K08M4_RS01890 de40b62261b32a7c43e0ef3778227b30 153 Gene3D G3DSA:3.30.70.140 2 98 4.5E-36 T 05-07-2017 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal K08M4_RS01890 de40b62261b32a7c43e0ef3778227b30 153 Gene3D G3DSA:2.30.30.20 101 152 4.9E-23 T 05-07-2017 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal K08M4_RS01890 de40b62261b32a7c43e0ef3778227b30 153 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 9 99 6.0E-43 T 05-07-2017 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal K08M4_RS01890 de40b62261b32a7c43e0ef3778227b30 153 SUPERFAMILY SSF54893 2 100 1.2E-35 T 05-07-2017 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 Gene3D G3DSA:3.30.310.50 472 562 7.6E-18 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 Gene3D G3DSA:3.40.120.10 306 451 1.4E-35 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 Gene3D G3DSA:3.40.120.10 228 305 1.3E-21 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 SUPERFAMILY SSF53738 30 222 5.1E-42 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 Gene3D G3DSA:3.40.120.10 13 213 6.6E-61 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 SUPERFAMILY SSF53738 202 311 2.04E-21 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 327 443 8.9E-19 T 05-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 40 176 1.9E-39 T 05-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 207 309 3.8E-25 T 05-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 SUPERFAMILY SSF53738 301 449 3.57E-27 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 138 147 - T 05-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 293 308 4.0E-7 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 245 4.0E-7 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 137 151 4.0E-7 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 SUPERFAMILY SSF55957 504 542 2.35E-12 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16715 3a1bb0e0a68bdac7efebda9d1b4099b3 574 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 502 544 3.0E-11 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16875 fbd38e218d1994011cb66b4358f468f7 353 Pfam PF01389 OmpA-like transmembrane domain 24 184 5.5E-23 T 05-07-2017 IPR000498 Outer membrane protein OmpA-like, transmembrane domain GO:0009279|GO:0016021 K08M4_RS16875 fbd38e218d1994011cb66b4358f468f7 353 SUPERFAMILY SSF56925 26 184 3.66E-33 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS16875 fbd38e218d1994011cb66b4358f468f7 353 Gene3D G3DSA:2.40.160.20 10 219 1.0E-47 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS16875 fbd38e218d1994011cb66b4358f468f7 353 Pfam PF00691 OmpA family 232 327 2.2E-24 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS16875 fbd38e218d1994011cb66b4358f468f7 353 SUPERFAMILY SSF103088 212 333 4.97E-34 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS16875 fbd38e218d1994011cb66b4358f468f7 353 PRINTS PR01021 OMPA domain signature 278 294 7.5E-10 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS16875 fbd38e218d1994011cb66b4358f468f7 353 PRINTS PR01021 OMPA domain signature 263 278 7.5E-10 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS16875 fbd38e218d1994011cb66b4358f468f7 353 PRINTS PR01021 OMPA domain signature 233 255 7.5E-10 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS16875 fbd38e218d1994011cb66b4358f468f7 353 Gene3D G3DSA:3.30.1330.60 221 333 1.3E-37 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS15285 b79fa452b0b4b1fce944920a54d8b281 537 Gene3D G3DSA:3.90.190.10 84 231 8.8E-27 T 05-07-2017 IPR029021 Protein-tyrosine phosphatase-like K08M4_RS15285 b79fa452b0b4b1fce944920a54d8b281 537 Gene3D G3DSA:3.40.50.10330 285 357 1.4E-5 T 05-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 K08M4_RS15285 b79fa452b0b4b1fce944920a54d8b281 537 SUPERFAMILY SSF111331 240 537 5.23E-53 T 05-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain K08M4_RS15285 b79fa452b0b4b1fce944920a54d8b281 537 Pfam PF00781 Diacylglycerol kinase catalytic domain 241 363 1.7E-25 T 05-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 K08M4_RS15285 b79fa452b0b4b1fce944920a54d8b281 537 SUPERFAMILY SSF52799 89 227 1.9E-26 T 05-07-2017 IPR029021 Protein-tyrosine phosphatase-like K08M4_RS15285 b79fa452b0b4b1fce944920a54d8b281 537 SMART SM00195 90 232 1.3E-6 T 05-07-2017 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 K08M4_RS15285 b79fa452b0b4b1fce944920a54d8b281 537 Pfam PF00782 Dual specificity phosphatase, catalytic domain 109 227 3.5E-15 T 05-07-2017 IPR000340 Dual specificity phosphatase, catalytic domain GO:0006470|GO:0008138 K08M4_RS15285 b79fa452b0b4b1fce944920a54d8b281 537 SMART SM00046 240 363 2.5E-4 T 05-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 K08M4_RS15285 b79fa452b0b4b1fce944920a54d8b281 537 SMART SM00404 135 232 0.0031 T 05-07-2017 IPR003595 Protein-tyrosine phosphatase, catalytic K08M4_RS17140 52d651f95a9fd84782ea32d514f16bbe 382 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 172 200 - T 05-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 K08M4_RS17140 52d651f95a9fd84782ea32d514f16bbe 382 Gene3D G3DSA:1.20.1090.10 183 382 8.6E-80 T 05-07-2017 K08M4_RS17140 52d651f95a9fd84782ea32d514f16bbe 382 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 374 3.0E-126 T 05-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 K08M4_RS17140 52d651f95a9fd84782ea32d514f16bbe 382 SUPERFAMILY SSF56796 4 381 2.62E-135 T 05-07-2017 K08M4_RS17140 52d651f95a9fd84782ea32d514f16bbe 382 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 259 279 - T 05-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 K08M4_RS17140 52d651f95a9fd84782ea32d514f16bbe 382 Gene3D G3DSA:3.40.50.1970 3 181 5.6E-61 T 05-07-2017 K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 227 242 - T 05-07-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 289 390 2.8E-17 T 05-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 5 412 1.4E-167 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 SUPERFAMILY SSF50621 259 413 3.35E-52 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 58 76 - T 05-07-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 78 90 8.0E-27 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 58 76 8.0E-27 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 370 383 8.0E-27 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 191 204 8.0E-27 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 272 291 8.0E-27 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 37 283 2.4E-72 T 05-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 Gene3D G3DSA:2.40.37.10 269 414 2.2E-48 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 Gene3D G3DSA:3.20.20.10 37 268 4.2E-81 T 05-07-2017 IPR029066 PLP-binding barrel K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 SUPERFAMILY SSF51419 27 284 1.31E-81 T 05-07-2017 IPR029066 PLP-binding barrel K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 165 174 5.1E-30 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 300 318 5.1E-30 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 76 93 5.1E-30 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 380 402 5.1E-30 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS00420 836847b84715a57fa08c3eb6e9fa146e 417 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 16 413 41.512 T 05-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS01425 2d95d0e04b3f44eca43f37b00e3ef2fa 129 Pfam PF02635 DsrE/DsrF-like family 4 129 9.1E-26 T 05-07-2017 IPR003787 Sulphur relay, DsrE/F-like protein K08M4_RS01425 2d95d0e04b3f44eca43f37b00e3ef2fa 129 TIGRFAM TIGR03012 sulf_tusD_dsrE: sulfur relay protein TusD/DsrE 4 129 1.4E-53 T 05-07-2017 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 K08M4_RS01425 2d95d0e04b3f44eca43f37b00e3ef2fa 129 Gene3D G3DSA:3.40.1260.10 3 129 1.8E-29 T 05-07-2017 IPR027396 DsrEFH-like K08M4_RS01425 2d95d0e04b3f44eca43f37b00e3ef2fa 129 SUPERFAMILY SSF75169 4 129 4.24E-36 T 05-07-2017 IPR027396 DsrEFH-like K08M4_RS20485 9cb746d3e4a8ddc648bbcb31d1e5aa5f 594 SUPERFAMILY SSF53850 117 592 5.61E-67 T 05-07-2017 K08M4_RS20485 9cb746d3e4a8ddc648bbcb31d1e5aa5f 594 Gene3D G3DSA:3.90.76.10 132 276 1.9E-21 T 05-07-2017 K08M4_RS20485 9cb746d3e4a8ddc648bbcb31d1e5aa5f 594 Pfam PF12793 Sugar transport-related sRNA regulator N-term 6 119 2.8E-36 T 05-07-2017 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain K08M4_RS20485 9cb746d3e4a8ddc648bbcb31d1e5aa5f 594 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 164 432 4.5E-23 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain K08M4_RS20485 9cb746d3e4a8ddc648bbcb31d1e5aa5f 594 Gene3D G3DSA:3.40.190.10 277 390 2.5E-8 T 05-07-2017 K08M4_RS03385 1f4a9701f2d349ea05b7b376fe2f2cd4 483 Gene3D G3DSA:3.40.50.300 231 458 5.3E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03385 1f4a9701f2d349ea05b7b376fe2f2cd4 483 Gene3D G3DSA:3.30.450.90 129 226 4.5E-37 T 05-07-2017 K08M4_RS03385 1f4a9701f2d349ea05b7b376fe2f2cd4 483 Pfam PF00437 Type II/IV secretion system protein 132 409 1.0E-85 T 05-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 K08M4_RS03385 1f4a9701f2d349ea05b7b376fe2f2cd4 483 SUPERFAMILY SSF52540 115 446 3.51E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04365 cfc5cb9c6b8fe264e8e76296a271478d 925 Pfam PF05193 Peptidase M16 inactive domain 182 354 1.2E-22 T 05-07-2017 IPR007863 Peptidase M16, C-terminal K08M4_RS04365 cfc5cb9c6b8fe264e8e76296a271478d 925 Pfam PF05193 Peptidase M16 inactive domain 648 823 2.5E-9 T 05-07-2017 IPR007863 Peptidase M16, C-terminal K08M4_RS04365 cfc5cb9c6b8fe264e8e76296a271478d 925 SUPERFAMILY SSF63411 703 904 1.92E-44 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 K08M4_RS04365 cfc5cb9c6b8fe264e8e76296a271478d 925 Pfam PF00675 Insulinase (Peptidase family M16) 21 156 3.6E-38 T 05-07-2017 IPR011765 Peptidase M16, N-terminal K08M4_RS04365 cfc5cb9c6b8fe264e8e76296a271478d 925 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 42 65 - T 05-07-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 K08M4_RS04365 cfc5cb9c6b8fe264e8e76296a271478d 925 SUPERFAMILY SSF63411 233 468 5.13E-75 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 K08M4_RS04365 cfc5cb9c6b8fe264e8e76296a271478d 925 Gene3D G3DSA:3.30.830.10 708 918 3.3E-47 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 K08M4_RS04365 cfc5cb9c6b8fe264e8e76296a271478d 925 Pfam PF16187 Middle or third domain of peptidase_M16 366 643 2.4E-82 T 05-07-2017 IPR032632 Peptidase M16, middle/third domain K08M4_RS04365 cfc5cb9c6b8fe264e8e76296a271478d 925 SUPERFAMILY SSF63411 4 226 2.79E-60 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 K08M4_RS04365 cfc5cb9c6b8fe264e8e76296a271478d 925 Gene3D G3DSA:3.30.830.10 4 229 5.1E-74 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 K08M4_RS04365 cfc5cb9c6b8fe264e8e76296a271478d 925 SUPERFAMILY SSF63411 470 694 1.76E-60 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 K08M4_RS04365 cfc5cb9c6b8fe264e8e76296a271478d 925 Gene3D G3DSA:3.30.830.10 242 471 1.4E-71 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 K08M4_RS04365 cfc5cb9c6b8fe264e8e76296a271478d 925 Gene3D G3DSA:3.30.830.10 472 707 1.1E-64 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 K08M4_RS09540 5fad5910acea36084470328217dd5687 287 Gene3D G3DSA:3.30.2010.10 73 160 1.9E-32 T 05-07-2017 K08M4_RS09540 5fad5910acea36084470328217dd5687 287 Pfam PF01435 Peptidase family M48 78 287 6.1E-40 T 05-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 K08M4_RS09540 5fad5910acea36084470328217dd5687 287 Hamap MF_00188 Protease HtpX [htpX]. 1 287 25.345 T 05-07-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 K08M4_RS09665 5fad5910acea36084470328217dd5687 287 Gene3D G3DSA:3.30.2010.10 73 160 1.9E-32 T 05-07-2017 K08M4_RS09665 5fad5910acea36084470328217dd5687 287 Pfam PF01435 Peptidase family M48 78 287 6.1E-40 T 05-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 K08M4_RS09665 5fad5910acea36084470328217dd5687 287 Hamap MF_00188 Protease HtpX [htpX]. 1 287 25.345 T 05-07-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 K08M4_RS04200 8e12dd63d69a67997e43c754f37507fb 146 Pfam PF04347 Flagellar biosynthesis protein, FliO 63 140 1.5E-16 T 05-07-2017 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 K08M4_RS04200 8e12dd63d69a67997e43c754f37507fb 146 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 51 118 5.6E-21 T 05-07-2017 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 K08M4_RS17620 096b6292ffc5d2b7ccfd9ddef483c2b1 171 Pfam PF13302 Acetyltransferase (GNAT) domain 4 144 8.8E-17 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS17620 096b6292ffc5d2b7ccfd9ddef483c2b1 171 SUPERFAMILY SSF55729 3 167 1.38E-27 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS17620 096b6292ffc5d2b7ccfd9ddef483c2b1 171 Gene3D G3DSA:3.40.630.30 3 167 1.1E-28 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS11305 0982779b35848ef348b1e0bd906a2877 231 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 1 146 1.4E-47 T 05-07-2017 IPR023370 TsaA-like domain K08M4_RS11305 0982779b35848ef348b1e0bd906a2877 231 Gene3D G3DSA:2.40.30.70 2 155 3.9E-50 T 05-07-2017 IPR023370 TsaA-like domain K08M4_RS11305 0982779b35848ef348b1e0bd906a2877 231 Pfam PF01980 Uncharacterised protein family UPF0066 19 141 1.9E-38 T 05-07-2017 IPR023370 TsaA-like domain K08M4_RS11305 0982779b35848ef348b1e0bd906a2877 231 SUPERFAMILY SSF118196 1 226 8.11E-78 T 05-07-2017 IPR023370 TsaA-like domain K08M4_RS11305 0982779b35848ef348b1e0bd906a2877 231 ProSitePatterns PS01318 TsaA-like domain signature. 85 96 - T 05-07-2017 IPR023368 Uncharacterised protein family UPF0066, conserved site K08M4_RS00820 55e974633004b305a3e37b95e8414e8f 164 Pfam PF00466 Ribosomal protein L10 5 101 5.9E-27 T 05-07-2017 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 K08M4_RS00820 55e974633004b305a3e37b95e8414e8f 164 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 159 24.464 T 05-07-2017 IPR022973 Ribosomal protein L10 K08M4_RS00820 55e974633004b305a3e37b95e8414e8f 164 SUPERFAMILY SSF160369 4 158 2.09E-45 T 05-07-2017 K08M4_RS00820 55e974633004b305a3e37b95e8414e8f 164 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 05-07-2017 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS20275 3293177bf5ea77762da269784b51f045 410 Pfam PF07687 Peptidase dimerisation domain 207 307 4.3E-9 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS20275 3293177bf5ea77762da269784b51f045 410 TIGRFAM TIGR01882 peptidase-T: peptidase T 2 404 9.2E-158 T 05-07-2017 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 K08M4_RS20275 3293177bf5ea77762da269784b51f045 410 SUPERFAMILY SSF53187 322 400 8.64E-75 T 05-07-2017 K08M4_RS20275 3293177bf5ea77762da269784b51f045 410 SUPERFAMILY SSF53187 1 210 8.64E-75 T 05-07-2017 K08M4_RS20275 3293177bf5ea77762da269784b51f045 410 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 73 82 - T 05-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 K08M4_RS20275 3293177bf5ea77762da269784b51f045 410 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 138 177 - T 05-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 K08M4_RS20275 3293177bf5ea77762da269784b51f045 410 PIRSF PIRSF037215 1 408 2.5E-178 T 05-07-2017 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 K08M4_RS20275 3293177bf5ea77762da269784b51f045 410 Hamap MF_00550 Peptidase T [pepT]. 1 404 55.349 T 05-07-2017 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 K08M4_RS20275 3293177bf5ea77762da269784b51f045 410 SUPERFAMILY SSF55031 209 319 5.96E-38 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS20275 3293177bf5ea77762da269784b51f045 410 Gene3D G3DSA:3.30.70.360 210 319 1.1E-42 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS20275 3293177bf5ea77762da269784b51f045 410 Pfam PF01546 Peptidase family M20/M25/M40 139 401 2.1E-12 T 05-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 K08M4_RS20275 3293177bf5ea77762da269784b51f045 410 Gene3D G3DSA:3.40.630.10 1 209 8.3E-114 T 05-07-2017 K08M4_RS20275 3293177bf5ea77762da269784b51f045 410 Gene3D G3DSA:3.40.630.10 322 405 8.3E-114 T 05-07-2017 K08M4_RS13885 2e8bd9b4b54b89306259bfdf47dc9d33 348 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 18 338 36.614 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 K08M4_RS13885 2e8bd9b4b54b89306259bfdf47dc9d33 348 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 72 99 1.0E-42 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 K08M4_RS13885 2e8bd9b4b54b89306259bfdf47dc9d33 348 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 189 213 1.0E-42 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 K08M4_RS13885 2e8bd9b4b54b89306259bfdf47dc9d33 348 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 22 39 1.0E-42 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 K08M4_RS13885 2e8bd9b4b54b89306259bfdf47dc9d33 348 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 214 238 1.0E-42 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 K08M4_RS13885 2e8bd9b4b54b89306259bfdf47dc9d33 348 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 148 168 1.0E-42 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 K08M4_RS13885 2e8bd9b4b54b89306259bfdf47dc9d33 348 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 254 271 1.0E-42 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 K08M4_RS13885 2e8bd9b4b54b89306259bfdf47dc9d33 348 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 20 174 4.4E-46 T 05-07-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 K08M4_RS13885 2e8bd9b4b54b89306259bfdf47dc9d33 348 PIRSF PIRSF000114 13 348 7.0E-95 T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 K08M4_RS13885 2e8bd9b4b54b89306259bfdf47dc9d33 348 SUPERFAMILY SSF48179 195 347 4.99E-56 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 K08M4_RS13885 2e8bd9b4b54b89306259bfdf47dc9d33 348 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 204 225 - T 05-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 K08M4_RS13885 2e8bd9b4b54b89306259bfdf47dc9d33 348 SUPERFAMILY SSF51735 20 194 1.61E-48 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13885 2e8bd9b4b54b89306259bfdf47dc9d33 348 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 196 333 2.1E-51 T 05-07-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 K08M4_RS13885 2e8bd9b4b54b89306259bfdf47dc9d33 348 Gene3D G3DSA:3.40.50.720 13 199 5.9E-52 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13885 2e8bd9b4b54b89306259bfdf47dc9d33 348 Gene3D G3DSA:1.10.1040.10 200 342 5.7E-58 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 K08M4_RS18395 f9bca171e5be243df24e920934f86350 292 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 27 283 8.6E-15 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS18395 f9bca171e5be243df24e920934f86350 292 Gene3D G3DSA:3.60.10.10 23 290 3.4E-24 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS18395 f9bca171e5be243df24e920934f86350 292 SUPERFAMILY SSF56219 21 290 1.57E-38 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS04850 93527869f14d683b096790118f43b630 138 SUPERFAMILY SSF54593 3 130 1.34E-34 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS04850 93527869f14d683b096790118f43b630 138 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 05-07-2017 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 K08M4_RS04850 93527869f14d683b096790118f43b630 138 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 5 136 1.8E-67 T 05-07-2017 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 K08M4_RS04850 93527869f14d683b096790118f43b630 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 126 5.1E-23 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain K08M4_RS04850 93527869f14d683b096790118f43b630 138 Gene3D G3DSA:3.10.180.10 5 131 2.1E-46 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS10100 00d1a9fb2995f17994918735ad81dd86 126 SUPERFAMILY SSF54593 2 125 3.24E-18 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS10100 00d1a9fb2995f17994918735ad81dd86 126 Gene3D G3DSA:3.10.180.10 1 122 2.5E-20 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS10100 00d1a9fb2995f17994918735ad81dd86 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 119 3.2E-7 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain K08M4_RS06650 a05c1416cab26d56d3ca607035d88bb3 399 SUPERFAMILY SSF103473 6 386 4.58E-54 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS06650 a05c1416cab26d56d3ca607035d88bb3 399 Gene3D G3DSA:1.20.1250.20 16 190 3.7E-26 T 05-07-2017 K08M4_RS06650 a05c1416cab26d56d3ca607035d88bb3 399 Gene3D G3DSA:1.20.1250.20 211 388 9.5E-10 T 05-07-2017 K08M4_RS06650 a05c1416cab26d56d3ca607035d88bb3 399 Pfam PF07690 Major Facilitator Superfamily 16 352 3.6E-38 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 SUPERFAMILY SSF53955 109 265 9.11E-40 T 05-07-2017 IPR023346 Lysozyme-like domain K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 SUPERFAMILY SSF54106 339 383 3.4E-10 T 05-07-2017 IPR018392 LysM domain K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 Gene3D G3DSA:1.10.530.10 105 268 7.9E-43 T 05-07-2017 K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 SUPERFAMILY SSF54106 470 515 4.97E-9 T 05-07-2017 IPR018392 LysM domain K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 Pfam PF01464 Transglycosylase SLT domain 124 223 3.7E-22 T 05-07-2017 IPR008258 Transglycosylase SLT domain 1 K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 130 158 - T 05-07-2017 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 SUPERFAMILY SSF54106 414 458 5.1E-11 T 05-07-2017 IPR018392 LysM domain K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 Pfam PF01476 LysM domain 472 513 2.9E-9 T 05-07-2017 IPR018392 LysM domain K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 Pfam PF01476 LysM domain 415 457 3.1E-12 T 05-07-2017 IPR018392 LysM domain K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 Pfam PF01476 LysM domain 341 383 2.1E-11 T 05-07-2017 IPR018392 LysM domain K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 SMART SM00257 340 383 2.9E-13 T 05-07-2017 IPR018392 LysM domain K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 SMART SM00257 471 515 3.4E-8 T 05-07-2017 IPR018392 LysM domain K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 SMART SM00257 414 458 1.4E-13 T 05-07-2017 IPR018392 LysM domain K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 Gene3D G3DSA:3.10.350.10 414 459 4.3E-17 T 05-07-2017 IPR018392 LysM domain K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 Gene3D G3DSA:3.10.350.10 469 515 3.8E-14 T 05-07-2017 IPR018392 LysM domain K08M4_RS11115 026875144c477818a7883b8ef004b3ee 523 Gene3D G3DSA:3.10.350.10 339 384 1.2E-15 T 05-07-2017 IPR018392 LysM domain K08M4_RS20495 b54046eecc8511061be58bdecb9253d9 142 Gene3D G3DSA:2.40.70.10 3 134 1.4E-40 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS20495 b54046eecc8511061be58bdecb9253d9 142 Pfam PF05618 Putative ATP-dependant zinc protease 6 139 9.8E-31 T 05-07-2017 K08M4_RS20495 b54046eecc8511061be58bdecb9253d9 142 SUPERFAMILY SSF50630 6 140 1.8E-39 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS02820 69da3063846324bd33e26ecd3b0adc8c 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.9E-9 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS02820 69da3063846324bd33e26ecd3b0adc8c 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.9E-9 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS02820 69da3063846324bd33e26ecd3b0adc8c 253 Gene3D G3DSA:1.20.120.530 98 238 3.5E-19 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS02820 69da3063846324bd33e26ecd3b0adc8c 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.7E-25 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS02820 69da3063846324bd33e26ecd3b0adc8c 253 SUPERFAMILY SSF48008 98 235 2.07E-20 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS02820 69da3063846324bd33e26ecd3b0adc8c 253 Gene3D G3DSA:1.10.10.10 7 77 1.8E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS02820 69da3063846324bd33e26ecd3b0adc8c 253 SMART SM00895 99 227 8.1E-19 T 05-07-2017 IPR011711 GntR, C-terminal K08M4_RS02820 69da3063846324bd33e26ecd3b0adc8c 253 SMART SM00345 15 74 9.9E-28 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS02820 69da3063846324bd33e26ecd3b0adc8c 253 Pfam PF07729 FCD domain 99 226 1.1E-18 T 05-07-2017 IPR011711 GntR, C-terminal K08M4_RS02820 69da3063846324bd33e26ecd3b0adc8c 253 SUPERFAMILY SSF46785 5 76 2.58E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05580 453feadbac6030496869181672bff0f8 180 Gene3D G3DSA:3.30.1330.60 68 179 2.5E-32 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS05580 453feadbac6030496869181672bff0f8 180 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 77 180 8.9E-44 T 05-07-2017 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 K08M4_RS05580 453feadbac6030496869181672bff0f8 180 PRINTS PR01021 OMPA domain signature 125 141 2.9E-16 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS05580 453feadbac6030496869181672bff0f8 180 PRINTS PR01021 OMPA domain signature 80 102 2.9E-16 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS05580 453feadbac6030496869181672bff0f8 180 PRINTS PR01021 OMPA domain signature 110 125 2.9E-16 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS05580 453feadbac6030496869181672bff0f8 180 ProSitePatterns PS01068 OmpA-like domain. 112 156 - T 05-07-2017 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 K08M4_RS05580 453feadbac6030496869181672bff0f8 180 SUPERFAMILY SSF103088 67 179 5.62E-32 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS05580 453feadbac6030496869181672bff0f8 180 Pfam PF00691 OmpA family 79 174 1.2E-21 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS14425 cf6fa88d9fd357571c1671d815287bbb 297 SUPERFAMILY SSF103481 42 144 7.85E-14 T 05-07-2017 K08M4_RS14425 cf6fa88d9fd357571c1671d815287bbb 297 Pfam PF00892 EamA-like transporter family 155 286 8.5E-17 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS14425 cf6fa88d9fd357571c1671d815287bbb 297 Pfam PF00892 EamA-like transporter family 9 141 2.9E-18 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS14425 cf6fa88d9fd357571c1671d815287bbb 297 SUPERFAMILY SSF103481 189 287 7.72E-10 T 05-07-2017 K08M4_RS00065 bbbcee60884b40135e0745da2860b130 313 Gene3D G3DSA:3.40.190.10 92 174 5.8E-21 T 05-07-2017 K08M4_RS00065 bbbcee60884b40135e0745da2860b130 313 Gene3D G3DSA:3.40.190.10 274 302 5.8E-21 T 05-07-2017 K08M4_RS00065 bbbcee60884b40135e0745da2860b130 313 SUPERFAMILY SSF53850 92 298 4.34E-39 T 05-07-2017 K08M4_RS00065 bbbcee60884b40135e0745da2860b130 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 1.1E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS00065 bbbcee60884b40135e0745da2860b130 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 1.1E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS00065 bbbcee60884b40135e0745da2860b130 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 1.1E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS00065 bbbcee60884b40135e0745da2860b130 313 Pfam PF03466 LysR substrate binding domain 100 299 1.0E-22 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS00065 bbbcee60884b40135e0745da2860b130 313 Gene3D G3DSA:1.10.10.10 5 89 8.7E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS00065 bbbcee60884b40135e0745da2860b130 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 7.8E-15 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS00065 bbbcee60884b40135e0745da2860b130 313 SUPERFAMILY SSF46785 7 87 6.8E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS00065 bbbcee60884b40135e0745da2860b130 313 Gene3D G3DSA:3.40.190.10 175 269 2.5E-22 T 05-07-2017 K08M4_RS20595 e5bcfdebd876cad5bbb34684889a2cb9 222 Pfam PF13309 HTH domain 160 217 3.5E-13 T 05-07-2017 K08M4_RS20595 e5bcfdebd876cad5bbb34684889a2cb9 222 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 13 135 7.0E-63 T 05-07-2017 IPR013559 YheO-like K08M4_RS20595 e5bcfdebd876cad5bbb34684889a2cb9 222 Gene3D G3DSA:1.10.10.60 176 218 6.0E-4 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20595 e5bcfdebd876cad5bbb34684889a2cb9 222 Pfam PF08348 YheO-like PAS domain 17 123 2.7E-34 T 05-07-2017 IPR013559 YheO-like K08M4_RS13680 03771da8c828dc1aa76c8235c74a799b 127 Pfam PF02300 Fumarate reductase subunit C 2 127 1.8E-48 T 05-07-2017 IPR003510 Fumarate reductase, subunit C GO:0016020 K08M4_RS13680 03771da8c828dc1aa76c8235c74a799b 127 Gene3D G3DSA:1.20.1300.10 1 127 5.5E-53 T 05-07-2017 K08M4_RS13680 03771da8c828dc1aa76c8235c74a799b 127 SUPERFAMILY SSF81343 1 127 1.02E-51 T 05-07-2017 K08M4_RS13680 03771da8c828dc1aa76c8235c74a799b 127 ProDom PD015900 FUMARATE MEMBRANE REDUCTASE C SUBUNIT TRANSMEMBRANE INNER HYDROPHOBIC REDUCTASE POLYPEPTIDE 7 127 2.0E-47 T 05-07-2017 IPR003510 Fumarate reductase, subunit C GO:0016020 K08M4_RS13680 03771da8c828dc1aa76c8235c74a799b 127 Hamap MF_00708 Fumarate reductase subunit C [frdC]. 1 127 26.968 T 05-07-2017 IPR003510 Fumarate reductase, subunit C GO:0016020 K08M4_RS13680 03771da8c828dc1aa76c8235c74a799b 127 PIRSF PIRSF000180 1 127 2.5E-56 T 05-07-2017 IPR003510 Fumarate reductase, subunit C GO:0016020 K08M4_RS14580 58cbb4f8c2c15c45551fac268515d925 413 Pfam PF03116 NQR2, RnfD, RnfE family 45 404 6.8E-104 T 05-07-2017 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 K08M4_RS14580 58cbb4f8c2c15c45551fac268515d925 413 TIGRFAM TIGR01937 nqrB: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit 3 407 9.1E-175 T 05-07-2017 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 K08M4_RS14580 58cbb4f8c2c15c45551fac268515d925 413 Hamap MF_00426 Na(+)-translocating NADH-quinone reductase subunit B [nqrB]. 2 411 34.987 T 05-07-2017 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 K08M4_RS14580 58cbb4f8c2c15c45551fac268515d925 413 PIRSF PIRSF016055 1 413 3.2E-184 T 05-07-2017 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 K08M4_RS15260 b1cf4a68cface5d61b76e9e57a450aca 446 SUPERFAMILY SSF52172 40 185 4.23E-7 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS15260 b1cf4a68cface5d61b76e9e57a450aca 446 Pfam PF00158 Sigma-54 interaction domain 142 309 1.8E-67 T 05-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 K08M4_RS15260 b1cf4a68cface5d61b76e9e57a450aca 446 Gene3D G3DSA:1.10.10.60 399 443 1.9E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS15260 b1cf4a68cface5d61b76e9e57a450aca 446 SMART SM00382 162 305 9.6E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS15260 b1cf4a68cface5d61b76e9e57a450aca 446 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 410 427 1.3E-5 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS15260 b1cf4a68cface5d61b76e9e57a450aca 446 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 427 446 1.3E-5 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS15260 b1cf4a68cface5d61b76e9e57a450aca 446 Gene3D G3DSA:3.40.50.300 139 314 3.1E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15260 b1cf4a68cface5d61b76e9e57a450aca 446 Gene3D G3DSA:1.10.8.60 315 382 3.4E-18 T 05-07-2017 K08M4_RS15260 b1cf4a68cface5d61b76e9e57a450aca 446 SUPERFAMILY SSF46689 354 444 4.3E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS15260 b1cf4a68cface5d61b76e9e57a450aca 446 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 354 363 - T 05-07-2017 IPR025944 Sigma-54 interaction domain, conserved site K08M4_RS15260 b1cf4a68cface5d61b76e9e57a450aca 446 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 05-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 K08M4_RS15260 b1cf4a68cface5d61b76e9e57a450aca 446 Pfam PF02954 Bacterial regulatory protein, Fis family 403 444 1.6E-13 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS15260 b1cf4a68cface5d61b76e9e57a450aca 446 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 05-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 K08M4_RS15260 b1cf4a68cface5d61b76e9e57a450aca 446 SUPERFAMILY SSF52540 142 379 2.98E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09535 df199ded0a96ae03faf33b3088b5ddff 456 SUPERFAMILY SSF48557 4 448 1.73E-108 T 05-07-2017 IPR008948 L-Aspartase-like GO:0003824 K08M4_RS09535 df199ded0a96ae03faf33b3088b5ddff 456 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 456 1.5E-149 T 05-07-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 K08M4_RS09535 df199ded0a96ae03faf33b3088b5ddff 456 Gene3D G3DSA:1.10.40.30 391 446 1.8E-33 T 05-07-2017 K08M4_RS09535 df199ded0a96ae03faf33b3088b5ddff 456 PRINTS PR00149 Fumarate lyase superfamily signature 163 181 5.2E-19 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS09535 df199ded0a96ae03faf33b3088b5ddff 456 PRINTS PR00149 Fumarate lyase superfamily signature 252 279 5.2E-19 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS09535 df199ded0a96ae03faf33b3088b5ddff 456 PRINTS PR00149 Fumarate lyase superfamily signature 295 311 5.2E-19 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS09535 df199ded0a96ae03faf33b3088b5ddff 456 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 5.2E-19 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS09535 df199ded0a96ae03faf33b3088b5ddff 456 Pfam PF00206 Lyase 14 313 3.9E-72 T 05-07-2017 IPR022761 Fumarate lyase, N-terminal K08M4_RS09535 df199ded0a96ae03faf33b3088b5ddff 456 ProSitePatterns PS00163 Fumarate lyases signature. 295 304 - T 05-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 K08M4_RS09535 df199ded0a96ae03faf33b3088b5ddff 456 Pfam PF08328 Adenylosuccinate lyase C-terminal 332 446 1.2E-51 T 05-07-2017 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 K08M4_RS09535 df199ded0a96ae03faf33b3088b5ddff 456 Gene3D G3DSA:1.10.275.10 1 119 1.5E-49 T 05-07-2017 IPR024083 Fumarase/histidase, N-terminal K08M4_RS09535 df199ded0a96ae03faf33b3088b5ddff 456 Gene3D G3DSA:1.20.200.10 120 390 6.7E-90 T 05-07-2017 K08M4_RS09660 df199ded0a96ae03faf33b3088b5ddff 456 SUPERFAMILY SSF48557 4 448 1.73E-108 T 05-07-2017 IPR008948 L-Aspartase-like GO:0003824 K08M4_RS09660 df199ded0a96ae03faf33b3088b5ddff 456 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 456 1.5E-149 T 05-07-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 K08M4_RS09660 df199ded0a96ae03faf33b3088b5ddff 456 Gene3D G3DSA:1.10.40.30 391 446 1.8E-33 T 05-07-2017 K08M4_RS09660 df199ded0a96ae03faf33b3088b5ddff 456 PRINTS PR00149 Fumarate lyase superfamily signature 163 181 5.2E-19 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS09660 df199ded0a96ae03faf33b3088b5ddff 456 PRINTS PR00149 Fumarate lyase superfamily signature 252 279 5.2E-19 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS09660 df199ded0a96ae03faf33b3088b5ddff 456 PRINTS PR00149 Fumarate lyase superfamily signature 295 311 5.2E-19 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS09660 df199ded0a96ae03faf33b3088b5ddff 456 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 5.2E-19 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS09660 df199ded0a96ae03faf33b3088b5ddff 456 Pfam PF00206 Lyase 14 313 3.9E-72 T 05-07-2017 IPR022761 Fumarate lyase, N-terminal K08M4_RS09660 df199ded0a96ae03faf33b3088b5ddff 456 ProSitePatterns PS00163 Fumarate lyases signature. 295 304 - T 05-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 K08M4_RS09660 df199ded0a96ae03faf33b3088b5ddff 456 Pfam PF08328 Adenylosuccinate lyase C-terminal 332 446 1.2E-51 T 05-07-2017 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 K08M4_RS09660 df199ded0a96ae03faf33b3088b5ddff 456 Gene3D G3DSA:1.10.275.10 1 119 1.5E-49 T 05-07-2017 IPR024083 Fumarase/histidase, N-terminal K08M4_RS09660 df199ded0a96ae03faf33b3088b5ddff 456 Gene3D G3DSA:1.20.200.10 120 390 6.7E-90 T 05-07-2017 K08M4_RS21435 7ee1e8b32224e3907f3582fba9857c9f 211 SUPERFAMILY SSF55961 20 197 1.86E-39 T 05-07-2017 K08M4_RS21435 7ee1e8b32224e3907f3582fba9857c9f 211 Gene3D G3DSA:3.30.530.20 11 199 7.4E-39 T 05-07-2017 IPR023393 START-like domain K08M4_RS21435 7ee1e8b32224e3907f3582fba9857c9f 211 Pfam PF01852 START domain 62 198 5.0E-8 T 05-07-2017 IPR002913 START domain GO:0008289 K08M4_RS21435 7ee1e8b32224e3907f3582fba9857c9f 211 PIRSF PIRSF039033 3 210 6.1E-56 T 05-07-2017 IPR028347 START domain-containing protein K08M4_RS14875 a7b0cd61d6b759a405c9d72c5c7e2360 322 ProSitePatterns PS00770 Aminotransferases class-IV signature. 194 223 - T 05-07-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 K08M4_RS14875 a7b0cd61d6b759a405c9d72c5c7e2360 322 Pfam PF01063 Amino-transferase class IV 36 268 1.3E-46 T 05-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 K08M4_RS14875 a7b0cd61d6b759a405c9d72c5c7e2360 322 SUPERFAMILY SSF56752 7 307 1.96E-103 T 05-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 K08M4_RS14875 a7b0cd61d6b759a405c9d72c5c7e2360 322 Gene3D G3DSA:3.30.470.10 7 130 4.9E-44 T 05-07-2017 K08M4_RS14875 a7b0cd61d6b759a405c9d72c5c7e2360 322 Gene3D G3DSA:3.20.10.10 134 295 5.3E-59 T 05-07-2017 K08M4_RS14875 a7b0cd61d6b759a405c9d72c5c7e2360 322 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 10 307 2.3E-141 T 05-07-2017 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 336 350 - T 05-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 SUPERFAMILY SSF100934 534 606 1.45E-5 T 05-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 Gene3D G3DSA:1.20.1270.10 531 600 2.3E-25 T 05-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 05-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 PRINTS PR00301 70kDa heat shock protein signature 53 61 1.1E-77 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 PRINTS PR00301 70kDa heat shock protein signature 197 207 1.1E-77 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 PRINTS PR00301 70kDa heat shock protein signature 468 484 1.1E-77 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 PRINTS PR00301 70kDa heat shock protein signature 137 157 1.1E-77 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.1E-77 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 PRINTS PR00301 70kDa heat shock protein signature 387 406 1.1E-77 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.1E-77 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 PRINTS PR00301 70kDa heat shock protein signature 333 349 1.1E-77 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 PRINTS PR00301 70kDa heat shock protein signature 364 384 1.1E-77 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 Gene3D G3DSA:3.30.420.40 4 52 8.2E-63 T 05-07-2017 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 Gene3D G3DSA:3.30.420.40 118 194 8.2E-63 T 05-07-2017 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 Gene3D G3DSA:3.30.30.30 53 106 4.2E-28 T 05-07-2017 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 632 35.969 T 05-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 191 204 - T 05-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 602 9.3E-282 T 05-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 Gene3D G3DSA:3.90.640.10 229 314 3.0E-31 T 05-07-2017 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 SUPERFAMILY SSF53067 1 182 2.36E-63 T 05-07-2017 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 Pfam PF00012 Hsp70 protein 4 601 1.3E-258 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 Gene3D G3DSA:2.60.34.10 389 530 1.0E-69 T 05-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 SUPERFAMILY SSF53067 186 381 5.06E-65 T 05-07-2017 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 Gene3D G3DSA:3.30.420.40 195 228 2.7E-31 T 05-07-2017 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 Gene3D G3DSA:3.30.420.40 318 360 2.7E-31 T 05-07-2017 K08M4_RS11685 c3666c5dc716d2b89b1c91a1f5da374d 637 SUPERFAMILY SSF100920 383 539 2.75E-59 T 05-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 K08M4_RS19235 a1c09a5252018a07827f86ad5822fd51 580 SMART SM00327 99 274 0.0036 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS19235 a1c09a5252018a07827f86ad5822fd51 580 Gene3D G3DSA:3.40.50.410 102 268 1.2E-5 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS19235 a1c09a5252018a07827f86ad5822fd51 580 Pfam PF13519 von Willebrand factor type A domain 102 207 2.7E-13 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS19235 a1c09a5252018a07827f86ad5822fd51 580 SUPERFAMILY SSF53300 99 272 7.91E-17 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS07805 5dbe1a0cd3b5f189d74f7931b3abcbee 336 Gene3D G3DSA:3.20.20.70 1 336 4.3E-127 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS07805 5dbe1a0cd3b5f189d74f7931b3abcbee 336 Pfam PF01180 Dihydroorotate dehydrogenase 47 336 1.5E-89 T 05-07-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 K08M4_RS07805 5dbe1a0cd3b5f189d74f7931b3abcbee 336 SUPERFAMILY SSF51395 1 336 5.86E-106 T 05-07-2017 K08M4_RS07805 5dbe1a0cd3b5f189d74f7931b3abcbee 336 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 292 312 - T 05-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 K08M4_RS07805 5dbe1a0cd3b5f189d74f7931b3abcbee 336 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 2 336 51.0 T 05-07-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS07805 5dbe1a0cd3b5f189d74f7931b3abcbee 336 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 80 99 - T 05-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 K08M4_RS07805 5dbe1a0cd3b5f189d74f7931b3abcbee 336 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 3 336 7.8E-149 T 05-07-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS07805 5dbe1a0cd3b5f189d74f7931b3abcbee 336 PIRSF PIRSF000164 10 336 1.3E-103 T 05-07-2017 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 K08M4_RS05145 514c7a0e5b12483c42848ece9a1e4dc0 210 ProSitePatterns PS01331 Thymidylate kinase signature. 96 108 - T 05-07-2017 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 K08M4_RS05145 514c7a0e5b12483c42848ece9a1e4dc0 210 Pfam PF02223 Thymidylate kinase 9 199 1.5E-56 T 05-07-2017 K08M4_RS05145 514c7a0e5b12483c42848ece9a1e4dc0 210 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 199 2.2E-61 T 05-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 K08M4_RS05145 514c7a0e5b12483c42848ece9a1e4dc0 210 Hamap MF_00165 Thymidylate kinase [tmk]. 5 207 27.511 T 05-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 K08M4_RS05145 514c7a0e5b12483c42848ece9a1e4dc0 210 SUPERFAMILY SSF52540 1 209 1.44E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05145 514c7a0e5b12483c42848ece9a1e4dc0 210 Gene3D G3DSA:3.40.50.300 4 208 9.9E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07355 0581ceb9b0b1e56ed726c856773c4064 503 SUPERFAMILY SSF46689 443 494 3.32E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS07355 0581ceb9b0b1e56ed726c856773c4064 503 Gene3D G3DSA:1.10.8.60 315 389 3.9E-22 T 05-07-2017 K08M4_RS07355 0581ceb9b0b1e56ed726c856773c4064 503 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 05-07-2017 IPR025944 Sigma-54 interaction domain, conserved site K08M4_RS07355 0581ceb9b0b1e56ed726c856773c4064 503 Pfam PF00158 Sigma-54 interaction domain 143 309 7.4E-68 T 05-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 K08M4_RS07355 0581ceb9b0b1e56ed726c856773c4064 503 SUPERFAMILY SSF52540 142 385 7.72E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07355 0581ceb9b0b1e56ed726c856773c4064 503 SMART SM00448 3 114 2.6E-23 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS07355 0581ceb9b0b1e56ed726c856773c4064 503 SUPERFAMILY SSF52172 3 186 9.96E-35 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS07355 0581ceb9b0b1e56ed726c856773c4064 503 Pfam PF00072 Response regulator receiver domain 5 114 2.1E-21 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS07355 0581ceb9b0b1e56ed726c856773c4064 503 Gene3D G3DSA:1.10.10.60 451 490 1.4E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS07355 0581ceb9b0b1e56ed726c856773c4064 503 SMART SM00382 162 304 1.6E-6 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS07355 0581ceb9b0b1e56ed726c856773c4064 503 Pfam PF02954 Bacterial regulatory protein, Fis family 454 490 1.1E-8 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS07355 0581ceb9b0b1e56ed726c856773c4064 503 Gene3D G3DSA:3.40.50.300 138 314 1.9E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07355 0581ceb9b0b1e56ed726c856773c4064 503 Gene3D G3DSA:3.40.50.2300 2 125 1.3E-28 T 05-07-2017 K08M4_RS07355 0581ceb9b0b1e56ed726c856773c4064 503 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 05-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 K08M4_RS20220 10b6b1d68a833ced31d4b7016065cc72 697 Pfam PF03880 DbpA RNA binding domain 507 573 6.0E-15 T 05-07-2017 IPR005580 DbpA, RNA-binding domain K08M4_RS20220 10b6b1d68a833ced31d4b7016065cc72 697 SMART SM00490 287 368 1.3E-34 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS20220 10b6b1d68a833ced31d4b7016065cc72 697 Gene3D G3DSA:3.40.50.300 241 406 1.7E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20220 10b6b1d68a833ced31d4b7016065cc72 697 SUPERFAMILY SSF52540 102 389 1.73E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20220 10b6b1d68a833ced31d4b7016065cc72 697 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 182 190 - T 05-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site K08M4_RS20220 10b6b1d68a833ced31d4b7016065cc72 697 Pfam PF00270 DEAD/DEAH box helicase 58 224 3.9E-49 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS20220 10b6b1d68a833ced31d4b7016065cc72 697 SMART SM00487 53 251 2.6E-57 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS20220 10b6b1d68a833ced31d4b7016065cc72 697 Pfam PF00271 Helicase conserved C-terminal domain 260 368 2.5E-29 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS20220 10b6b1d68a833ced31d4b7016065cc72 697 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 29 584 41.659 T 05-07-2017 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 K08M4_RS20220 10b6b1d68a833ced31d4b7016065cc72 697 Gene3D G3DSA:3.40.50.300 29 240 4.1E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16430 b57392419f47f66a113b2d957c31636b 614 Pfam PF00563 EAL domain 368 597 1.9E-58 T 05-07-2017 IPR001633 EAL domain K08M4_RS16430 b57392419f47f66a113b2d957c31636b 614 SUPERFAMILY SSF141868 368 608 7.06E-72 T 05-07-2017 IPR001633 EAL domain K08M4_RS16430 b57392419f47f66a113b2d957c31636b 614 Gene3D G3DSA:3.30.70.270 183 340 2.6E-32 T 05-07-2017 K08M4_RS16430 b57392419f47f66a113b2d957c31636b 614 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 181 327 6.2E-24 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS16430 b57392419f47f66a113b2d957c31636b 614 SMART SM00052 349 602 2.3E-73 T 05-07-2017 IPR001633 EAL domain K08M4_RS16430 b57392419f47f66a113b2d957c31636b 614 Gene3D G3DSA:3.20.20.450 368 608 7.0E-75 T 05-07-2017 IPR001633 EAL domain K08M4_RS16430 b57392419f47f66a113b2d957c31636b 614 SMART SM00267 170 335 1.0E-25 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS16430 b57392419f47f66a113b2d957c31636b 614 Pfam PF00990 Diguanylate cyclase, GGDEF domain 182 327 4.6E-27 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS16430 b57392419f47f66a113b2d957c31636b 614 SUPERFAMILY SSF55073 186 336 2.2E-28 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS00585 f96bbd96db258ac5ba341270fb2755ab 135 Pfam PF03748 Flagellar basal body-associated protein FliL 33 135 1.7E-19 T 05-07-2017 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 K08M4_RS00555 64dd3cc076fbcfd78a096089f5287e5c 411 SUPERFAMILY SSF52540 203 408 2.05E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00555 64dd3cc076fbcfd78a096089f5287e5c 411 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 381 394 - T 05-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 K08M4_RS00555 64dd3cc076fbcfd78a096089f5287e5c 411 Gene3D G3DSA:3.40.50.300 204 408 3.7E-81 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00555 64dd3cc076fbcfd78a096089f5287e5c 411 Pfam PF02881 SRP54-type protein, helical bundle domain 127 188 1.8E-13 T 05-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 K08M4_RS00555 64dd3cc076fbcfd78a096089f5287e5c 411 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 135 408 64.599 T 05-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 K08M4_RS00555 64dd3cc076fbcfd78a096089f5287e5c 411 SMART SM00382 206 386 4.0E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS00555 64dd3cc076fbcfd78a096089f5287e5c 411 SUPERFAMILY SSF47364 107 186 1.57E-22 T 05-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 K08M4_RS00555 64dd3cc076fbcfd78a096089f5287e5c 411 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 136 407 3.2E-115 T 05-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 K08M4_RS00555 64dd3cc076fbcfd78a096089f5287e5c 411 SMART SM00963 112 192 2.6E-25 T 05-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 K08M4_RS00555 64dd3cc076fbcfd78a096089f5287e5c 411 Pfam PF00448 SRP54-type protein, GTPase domain 208 407 1.0E-77 T 05-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 K08M4_RS00555 64dd3cc076fbcfd78a096089f5287e5c 411 SMART SM00962 207 408 2.0E-124 T 05-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 K08M4_RS00555 64dd3cc076fbcfd78a096089f5287e5c 411 Gene3D G3DSA:1.20.120.140 99 188 6.8E-33 T 05-07-2017 K08M4_RS20340 6cf411916dc737d7644c0428a0a09b9f 302 SUPERFAMILY SSF51430 7 293 2.36E-70 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain K08M4_RS20340 6cf411916dc737d7644c0428a0a09b9f 302 Gene3D G3DSA:3.20.20.100 4 292 1.6E-64 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain K08M4_RS20340 6cf411916dc737d7644c0428a0a09b9f 302 Pfam PF00248 Aldo/keto reductase family 16 291 8.4E-60 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain K08M4_RS20340 6cf411916dc737d7644c0428a0a09b9f 302 PRINTS PR00069 Aldo-keto reductase signature 145 162 4.1E-5 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 K08M4_RS20340 6cf411916dc737d7644c0428a0a09b9f 302 PRINTS PR00069 Aldo-keto reductase signature 114 132 4.1E-5 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 K08M4_RS01570 756d9a7dbdd6c76983597e7873ac5986 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 05-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01570 756d9a7dbdd6c76983597e7873ac5986 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.137 T 05-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01570 756d9a7dbdd6c76983597e7873ac5986 37 Pfam PF00444 Ribosomal protein L36 1 37 8.8E-19 T 05-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01570 756d9a7dbdd6c76983597e7873ac5986 37 SUPERFAMILY SSF57840 1 37 1.02E-16 T 05-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01570 756d9a7dbdd6c76983597e7873ac5986 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 3.0E-9 T 05-07-2017 K08M4_RS01570 756d9a7dbdd6c76983597e7873ac5986 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 4.0E-23 T 05-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS14675 76e06670c6faa8f73960e5665affbec9 294 Gene3D G3DSA:1.10.10.10 1 83 8.2E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS14675 76e06670c6faa8f73960e5665affbec9 294 Gene3D G3DSA:3.40.190.10 86 199 7.7E-19 T 05-07-2017 K08M4_RS14675 76e06670c6faa8f73960e5665affbec9 294 Gene3D G3DSA:3.40.190.10 200 262 2.1E-11 T 05-07-2017 K08M4_RS14675 76e06670c6faa8f73960e5665affbec9 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.4E-18 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS14675 76e06670c6faa8f73960e5665affbec9 294 SUPERFAMILY SSF53850 87 290 4.02E-32 T 05-07-2017 K08M4_RS14675 76e06670c6faa8f73960e5665affbec9 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.2E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS14675 76e06670c6faa8f73960e5665affbec9 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.2E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS14675 76e06670c6faa8f73960e5665affbec9 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.2E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS14675 76e06670c6faa8f73960e5665affbec9 294 Pfam PF03466 LysR substrate binding domain 87 289 1.1E-35 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS14675 76e06670c6faa8f73960e5665affbec9 294 SUPERFAMILY SSF46785 1 84 4.84E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS13475 ac382891acc43cb22dd45b837d0cc957 246 SUPERFAMILY SSF55315 3 77 2.12E-19 T 05-07-2017 IPR029064 50S ribosomal protein L30e-like K08M4_RS13475 ac382891acc43cb22dd45b837d0cc957 246 Gene3D G3DSA:3.40.1280.10 91 244 6.5E-56 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal K08M4_RS13475 ac382891acc43cb22dd45b837d0cc957 246 SMART SM00967 5 81 2.4E-17 T 05-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 K08M4_RS13475 ac382891acc43cb22dd45b837d0cc957 246 Pfam PF00588 SpoU rRNA Methylase family 97 237 6.5E-39 T 05-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 K08M4_RS13475 ac382891acc43cb22dd45b837d0cc957 246 SUPERFAMILY SSF75217 72 244 1.05E-47 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases K08M4_RS13475 ac382891acc43cb22dd45b837d0cc957 246 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 4 243 1.8E-85 T 05-07-2017 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 K08M4_RS13475 ac382891acc43cb22dd45b837d0cc957 246 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 5 79 7.8E-18 T 05-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 K08M4_RS13475 ac382891acc43cb22dd45b837d0cc957 246 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 3 244 43.595 T 05-07-2017 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB K08M4_RS13475 ac382891acc43cb22dd45b837d0cc957 246 Gene3D G3DSA:3.30.1330.30 2 77 9.8E-25 T 05-07-2017 IPR029064 50S ribosomal protein L30e-like K08M4_RS02150 637d003ac3867208267348a5979cd974 272 Gene3D G3DSA:3.40.50.720 2 160 1.9E-47 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS02150 637d003ac3867208267348a5979cd974 272 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 268 2.6E-30 T 05-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 K08M4_RS02150 637d003ac3867208267348a5979cd974 272 SUPERFAMILY SSF48179 163 270 2.55E-30 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 K08M4_RS02150 637d003ac3867208267348a5979cd974 272 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 99 1.2E-24 T 05-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal K08M4_RS02150 637d003ac3867208267348a5979cd974 272 Gene3D G3DSA:1.10.3730.10 163 268 3.3E-30 T 05-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 K08M4_RS02150 637d003ac3867208267348a5979cd974 272 PIRSF PIRSF000193 3 270 3.2E-76 T 05-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 K08M4_RS02150 637d003ac3867208267348a5979cd974 272 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 268 4.4E-73 T 05-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 K08M4_RS02150 637d003ac3867208267348a5979cd974 272 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 268 25.678 T 05-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 K08M4_RS02150 637d003ac3867208267348a5979cd974 272 SUPERFAMILY SSF51735 4 160 3.08E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS02150 637d003ac3867208267348a5979cd974 272 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 224 246 - T 05-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 K08M4_RS18430 fb4f15aded8849689522614eaa984b51 535 Gene3D G3DSA:3.40.50.300 2 270 3.8E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18430 fb4f15aded8849689522614eaa984b51 535 Gene3D G3DSA:3.40.50.300 318 529 5.7E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18430 fb4f15aded8849689522614eaa984b51 535 SUPERFAMILY SSF52540 309 526 1.35E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18430 fb4f15aded8849689522614eaa984b51 535 Pfam PF12848 ABC transporter 224 307 1.3E-20 T 05-07-2017 IPR032781 ABC-transporter extension domain K08M4_RS18430 fb4f15aded8849689522614eaa984b51 535 ProSitePatterns PS00211 ABC transporters family signature. 439 453 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS18430 fb4f15aded8849689522614eaa984b51 535 SUPERFAMILY SSF52540 4 238 6.8E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18430 fb4f15aded8849689522614eaa984b51 535 SMART SM00382 344 513 3.7E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS18430 fb4f15aded8849689522614eaa984b51 535 SMART SM00382 26 238 1.3E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS18430 fb4f15aded8849689522614eaa984b51 535 Pfam PF00005 ABC transporter 18 184 2.1E-20 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS18430 fb4f15aded8849689522614eaa984b51 535 Pfam PF00005 ABC transporter 339 467 6.5E-18 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS10650 df092a661b8630e90223aeb011d79c5e 515 Gene3D G3DSA:3.30.1360.60 429 503 7.0E-25 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS10650 df092a661b8630e90223aeb011d79c5e 515 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 3 501 4.0E-210 T 05-07-2017 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 K08M4_RS10650 df092a661b8630e90223aeb011d79c5e 515 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 403 490 1.6E-20 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS10650 df092a661b8630e90223aeb011d79c5e 515 SUPERFAMILY SSF55604 430 502 1.7E-19 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS10650 df092a661b8630e90223aeb011d79c5e 515 Pfam PF00367 phosphotransferase system, EIIB 432 465 1.4E-13 T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS10650 df092a661b8630e90223aeb011d79c5e 515 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 443 460 - T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS10650 df092a661b8630e90223aeb011d79c5e 515 Pfam PF02378 Phosphotransferase system, EIIC 11 345 1.1E-65 T 05-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 K08M4_RS06830 c525adc89768a2a4284faa90c891d0db 462 SUPERFAMILY SSF116734 3 211 1.57E-35 T 05-07-2017 K08M4_RS06830 c525adc89768a2a4284faa90c891d0db 462 Pfam PF01420 Type I restriction modification DNA specificity domain 240 395 1.9E-10 T 05-07-2017 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 K08M4_RS06830 c525adc89768a2a4284faa90c891d0db 462 Pfam PF01420 Type I restriction modification DNA specificity domain 5 187 1.3E-10 T 05-07-2017 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 K08M4_RS06830 c525adc89768a2a4284faa90c891d0db 462 SUPERFAMILY SSF116734 218 428 9.81E-32 T 05-07-2017 K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 SUPERFAMILY SSF103088 157 287 4.05E-28 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 Gene3D G3DSA:3.30.1330.60 185 288 1.3E-27 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 85 103 4.0E-148 T 05-07-2017 K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 123 145 4.0E-148 T 05-07-2017 K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 233 250 4.0E-148 T 05-07-2017 K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 104 121 4.0E-148 T 05-07-2017 K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 148 167 4.0E-148 T 05-07-2017 K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 271 291 4.0E-148 T 05-07-2017 K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 174 201 4.0E-148 T 05-07-2017 K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 3 27 4.0E-148 T 05-07-2017 K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 251 270 4.0E-148 T 05-07-2017 K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 28 44 4.0E-148 T 05-07-2017 K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 66 84 4.0E-148 T 05-07-2017 K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 45 63 4.0E-148 T 05-07-2017 K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 204 230 4.0E-148 T 05-07-2017 K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 Pfam PF00691 OmpA family 187 282 6.9E-20 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS04840 c99cae4031062382e36032a5177c2088 293 ProSitePatterns PS01068 OmpA-like domain. 220 264 - T 05-07-2017 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 K08M4_RS06175 d682f73c9123f46d480f9d2ee0217a58 584 Pfam PF00474 Sodium:solute symporter family 32 416 6.1E-41 T 05-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 K08M4_RS01605 6e6d765382b8c23f41313bab2572d417 206 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 2 108 7.0E-24 T 05-07-2017 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 K08M4_RS01605 6e6d765382b8c23f41313bab2572d417 206 Gene3D G3DSA:1.10.287.460 2 88 6.5E-24 T 05-07-2017 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 K08M4_RS01605 6e6d765382b8c23f41313bab2572d417 206 SUPERFAMILY SSF54534 7 205 2.75E-54 T 05-07-2017 K08M4_RS01605 6e6d765382b8c23f41313bab2572d417 206 Gene3D G3DSA:3.10.50.40 89 205 1.1E-48 T 05-07-2017 K08M4_RS01605 6e6d765382b8c23f41313bab2572d417 206 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 116 203 1.2E-26 T 05-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 K08M4_RS04055 b693c95e254f4071a0c0db6d6b327027 434 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 356 433 1.9E-14 T 05-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain K08M4_RS04055 b693c95e254f4071a0c0db6d6b327027 434 Pfam PF07559 Flagellar basal body protein FlaE 181 314 1.0E-20 T 05-07-2017 IPR011491 Flagellar hook protein FlgE K08M4_RS04055 b693c95e254f4071a0c0db6d6b327027 434 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 2 416 4.1E-92 T 05-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G K08M4_RS04055 b693c95e254f4071a0c0db6d6b327027 434 SUPERFAMILY SSF117143 78 395 2.75E-66 T 05-07-2017 K08M4_RS04055 b693c95e254f4071a0c0db6d6b327027 434 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 8 28 - T 05-07-2017 IPR019776 Flagellar basal body rod protein, conserved site K08M4_RS04055 b693c95e254f4071a0c0db6d6b327027 434 Pfam PF00460 Flagella basal body rod protein 3 32 7.2E-10 T 05-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 K08M4_RS04055 b693c95e254f4071a0c0db6d6b327027 434 PRINTS PR01005 Flagellar hook-associated protein signature 8 31 3.0E-5 T 05-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 K08M4_RS04055 b693c95e254f4071a0c0db6d6b327027 434 PRINTS PR01005 Flagellar hook-associated protein signature 239 261 3.0E-5 T 05-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 K08M4_RS07685 17e6cf9e6261b749cdedf5777537bac3 300 SUPERFAMILY SSF46689 10 115 5.2E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS07685 17e6cf9e6261b749cdedf5777537bac3 300 Gene3D G3DSA:3.30.420.10 131 292 3.3E-19 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS07685 17e6cf9e6261b749cdedf5777537bac3 300 SUPERFAMILY SSF53098 132 292 7.59E-18 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS07895 e38c4fa4ff488ff61b3f0cb6899ea4a3 313 SUPERFAMILY SSF51735 1 113 9.45E-26 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS07895 e38c4fa4ff488ff61b3f0cb6899ea4a3 313 Pfam PF13241 Putative NAD(P)-binding 6 116 2.9E-28 T 05-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 K08M4_RS07895 e38c4fa4ff488ff61b3f0cb6899ea4a3 313 Gene3D G3DSA:1.10.8.210 150 209 5.2E-19 T 05-07-2017 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 K08M4_RS07895 e38c4fa4ff488ff61b3f0cb6899ea4a3 313 Gene3D G3DSA:3.40.50.720 1 113 4.7E-38 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS07895 e38c4fa4ff488ff61b3f0cb6899ea4a3 313 Pfam PF10414 Sirohaem synthase dimerisation region 151 204 1.9E-13 T 05-07-2017 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 K08M4_RS07895 e38c4fa4ff488ff61b3f0cb6899ea4a3 313 SUPERFAMILY SSF75615 115 201 7.85E-25 T 05-07-2017 K08M4_RS07895 e38c4fa4ff488ff61b3f0cb6899ea4a3 313 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 198 5.2E-60 T 05-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 K08M4_RS07895 e38c4fa4ff488ff61b3f0cb6899ea4a3 313 Gene3D G3DSA:3.30.160.110 114 149 5.8E-18 T 05-07-2017 K08M4_RS07895 e38c4fa4ff488ff61b3f0cb6899ea4a3 313 Pfam PF14824 Sirohaem biosynthesis protein central 120 145 6.5E-9 T 05-07-2017 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 K08M4_RS14255 1291577945992ca33b34237ad1877c99 128 SUPERFAMILY SSF55174 8 105 3.53E-31 T 05-07-2017 K08M4_RS14255 1291577945992ca33b34237ad1877c99 128 Pfam PF01479 S4 domain 8 54 3.8E-13 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS14255 1291577945992ca33b34237ad1877c99 128 Gene3D G3DSA:3.10.290.10 6 103 1.9E-39 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS14255 1291577945992ca33b34237ad1877c99 128 PIRSF PIRSF016821 5 128 1.9E-41 T 05-07-2017 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 K08M4_RS14255 1291577945992ca33b34237ad1877c99 128 SMART SM00363 8 71 8.5E-12 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS16555 d160a9f770e90996647efd9683c67478 70 Gene3D G3DSA:2.40.50.140 5 68 4.3E-31 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS16555 d160a9f770e90996647efd9683c67478 70 Pfam PF00313 'Cold-shock' DNA-binding domain 6 69 1.7E-30 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS16555 d160a9f770e90996647efd9683c67478 70 PRINTS PR00050 Cold shock protein signature 28 37 4.0E-18 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS16555 d160a9f770e90996647efd9683c67478 70 PRINTS PR00050 Cold shock protein signature 43 61 4.0E-18 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS16555 d160a9f770e90996647efd9683c67478 70 PRINTS PR00050 Cold shock protein signature 7 22 4.0E-18 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS16555 d160a9f770e90996647efd9683c67478 70 SMART SM00357 6 70 1.4E-30 T 05-07-2017 IPR011129 Cold shock protein GO:0003676 K08M4_RS16555 d160a9f770e90996647efd9683c67478 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 05-07-2017 IPR019844 Cold-shock conserved site K08M4_RS16555 d160a9f770e90996647efd9683c67478 70 PIRSF PIRSF002599 1 70 8.0E-26 T 05-07-2017 IPR012156 Cold shock, CspA GO:0003676 K08M4_RS16555 d160a9f770e90996647efd9683c67478 70 SUPERFAMILY SSF50249 4 68 1.05E-25 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS19645 51c5aa3a9cda79e5c6f84cfeba01c9eb 304 Gene3D G3DSA:3.80.30.10 130 288 7.8E-43 T 05-07-2017 K08M4_RS19645 51c5aa3a9cda79e5c6f84cfeba01c9eb 304 ProSitePatterns PS01087 Radical activating enzymes signature. 35 56 - T 05-07-2017 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 K08M4_RS19645 51c5aa3a9cda79e5c6f84cfeba01c9eb 304 SUPERFAMILY SSF54862 44 152 3.97E-16 T 05-07-2017 K08M4_RS19645 51c5aa3a9cda79e5c6f84cfeba01c9eb 304 Gene3D G3DSA:3.30.70.20 61 104 7.9E-11 T 05-07-2017 K08M4_RS19645 51c5aa3a9cda79e5c6f84cfeba01c9eb 304 TIGRFAM TIGR04041 activase_YjjW: glycine radical enzyme activase, YjjW family 21 297 7.2E-128 T 05-07-2017 IPR023912 Putative glycyl-radical enzyme activating enzyme YjjW K08M4_RS19645 51c5aa3a9cda79e5c6f84cfeba01c9eb 304 PIRSF PIRSF000371 13 303 7.5E-90 T 05-07-2017 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 K08M4_RS19645 51c5aa3a9cda79e5c6f84cfeba01c9eb 304 SUPERFAMILY SSF102114 104 280 1.61E-14 T 05-07-2017 K08M4_RS19645 51c5aa3a9cda79e5c6f84cfeba01c9eb 304 Pfam PF04055 Radical SAM superfamily 42 241 4.7E-21 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS19645 51c5aa3a9cda79e5c6f84cfeba01c9eb 304 Pfam PF13353 4Fe-4S single cluster domain 33 158 9.5E-12 T 05-07-2017 K08M4_RS15150 d5adaf883139194bc66e403d36f2ff34 428 Gene3D G3DSA:3.40.50.300 142 246 2.9E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15150 d5adaf883139194bc66e403d36f2ff34 428 Gene3D G3DSA:3.40.50.2300 2 133 4.6E-34 T 05-07-2017 K08M4_RS15150 d5adaf883139194bc66e403d36f2ff34 428 SUPERFAMILY SSF52540 143 344 1.25E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15150 d5adaf883139194bc66e403d36f2ff34 428 Gene3D G3DSA:1.10.8.60 289 336 1.0E-11 T 05-07-2017 K08M4_RS15150 d5adaf883139194bc66e403d36f2ff34 428 SUPERFAMILY SSF52172 2 188 8.68E-38 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS15150 d5adaf883139194bc66e403d36f2ff34 428 Pfam PF00072 Response regulator receiver domain 6 114 5.2E-26 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS15150 d5adaf883139194bc66e403d36f2ff34 428 SUPERFAMILY SSF46689 372 421 1.15E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS15150 d5adaf883139194bc66e403d36f2ff34 428 Pfam PF02954 Bacterial regulatory protein, Fis family 380 418 3.9E-7 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS15150 d5adaf883139194bc66e403d36f2ff34 428 Gene3D G3DSA:1.10.10.60 337 420 3.1E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS15150 d5adaf883139194bc66e403d36f2ff34 428 SMART SM00448 2 113 1.0E-30 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS15150 d5adaf883139194bc66e403d36f2ff34 428 Pfam PF14532 Sigma-54 interaction domain 144 248 1.3E-6 T 05-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 K08M4_RS07190 ae2855495c877058ae2613b34d1c57d7 247 Gene3D G3DSA:3.40.190.10 207 246 2.3E-43 T 05-07-2017 K08M4_RS07190 ae2855495c877058ae2613b34d1c57d7 247 Gene3D G3DSA:3.40.190.10 24 112 2.3E-43 T 05-07-2017 K08M4_RS07190 ae2855495c877058ae2613b34d1c57d7 247 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 3 245 3.2E-81 T 05-07-2017 IPR005768 Lysine-arginine-ornithine-binding periplasmic protein GO:0005215|GO:0006810|GO:0030288 K08M4_RS07190 ae2855495c877058ae2613b34d1c57d7 247 SMART SM00079 26 247 0.0017 T 05-07-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 K08M4_RS07190 ae2855495c877058ae2613b34d1c57d7 247 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 49 62 - T 05-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 K08M4_RS07190 ae2855495c877058ae2613b34d1c57d7 247 SMART SM00062 26 247 5.6E-71 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS07190 ae2855495c877058ae2613b34d1c57d7 247 Gene3D G3DSA:3.40.190.10 121 205 2.7E-24 T 05-07-2017 K08M4_RS07190 ae2855495c877058ae2613b34d1c57d7 247 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 27 247 1.7E-63 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS07190 ae2855495c877058ae2613b34d1c57d7 247 SUPERFAMILY SSF53850 1 246 7.56E-66 T 05-07-2017 K08M4_RS00945 5112c78113f667868844c2af5e9b68df 609 Pfam PF00571 CBS domain 224 277 0.0021 T 05-07-2017 IPR000644 CBS domain K08M4_RS00945 5112c78113f667868844c2af5e9b68df 609 Pfam PF00027 Cyclic nucleotide-binding domain 32 113 3.0E-7 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain K08M4_RS00945 5112c78113f667868844c2af5e9b68df 609 Gene3D G3DSA:2.60.120.10 10 129 1.8E-10 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS00945 5112c78113f667868844c2af5e9b68df 609 Gene3D G3DSA:3.10.580.10 149 278 4.7E-18 T 05-07-2017 K08M4_RS00945 5112c78113f667868844c2af5e9b68df 609 Pfam PF03445 Putative nucleotidyltransferase DUF294 303 434 9.9E-43 T 05-07-2017 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 K08M4_RS00945 5112c78113f667868844c2af5e9b68df 609 SUPERFAMILY SSF51206 10 130 6.02E-15 T 05-07-2017 IPR018490 Cyclic nucleotide-binding-like K08M4_RS00945 5112c78113f667868844c2af5e9b68df 609 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 472 605 3.8E-37 T 05-07-2017 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding K08M4_RS00945 5112c78113f667868844c2af5e9b68df 609 SUPERFAMILY SSF54631 146 277 1.77E-18 T 05-07-2017 K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 Gene3D G3DSA:3.40.50.2300 485 611 3.4E-25 T 05-07-2017 K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 Pfam PF00072 Response regulator receiver domain 676 789 2.3E-24 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 Pfam PF00072 Response regulator receiver domain 488 601 2.4E-15 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 SUPERFAMILY SSF47384 226 308 4.12E-21 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 Pfam PF00512 His Kinase A (phospho-acceptor) domain 243 307 1.0E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 SMART SM00448 674 789 4.5E-33 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 SMART SM00448 486 604 1.4E-16 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 411 1.1E-11 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 1.1E-11 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 1.1E-11 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 425 1.1E-11 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 Gene3D G3DSA:3.40.50.2300 675 805 1.1E-40 T 05-07-2017 K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 SUPERFAMILY SSF52172 675 793 1.18E-33 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 SUPERFAMILY SSF52172 484 612 4.27E-24 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 SUPERFAMILY SSF55874 296 467 3.93E-42 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 SMART SM00387 354 472 1.1E-34 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 Pfam PF17149 Periplasmic sensor domain found in signal transduction proteins 39 141 3.1E-10 T 05-07-2017 IPR033414 Periplasmic sensor domain K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 Gene3D G3DSA:1.10.287.130 239 303 4.7E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 Gene3D G3DSA:3.30.565.10 308 470 4.5E-43 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 471 1.3E-27 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21850 4b758854a3c2121a66c92e7e7f7f7817 808 SMART SM00388 242 307 4.0E-24 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS00285 5d82ebe6f8c01db1093e726be5423b1c 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 4.7E-37 T 05-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 K08M4_RS00285 5d82ebe6f8c01db1093e726be5423b1c 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 05-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 K08M4_RS00285 5d82ebe6f8c01db1093e726be5423b1c 108 PRINTS PR00421 Thioredoxin family signature 24 32 3.3E-10 T 05-07-2017 K08M4_RS00285 5d82ebe6f8c01db1093e726be5423b1c 108 PRINTS PR00421 Thioredoxin family signature 72 83 3.3E-10 T 05-07-2017 K08M4_RS00285 5d82ebe6f8c01db1093e726be5423b1c 108 PRINTS PR00421 Thioredoxin family signature 32 41 3.3E-10 T 05-07-2017 K08M4_RS00285 5d82ebe6f8c01db1093e726be5423b1c 108 Pfam PF00085 Thioredoxin 5 106 6.9E-33 T 05-07-2017 IPR013766 Thioredoxin domain GO:0045454 K08M4_RS00285 5d82ebe6f8c01db1093e726be5423b1c 108 PIRSF PIRSF000077 2 108 2.1E-42 T 05-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 K08M4_RS00285 5d82ebe6f8c01db1093e726be5423b1c 108 SUPERFAMILY SSF52833 3 107 1.66E-38 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS00285 5d82ebe6f8c01db1093e726be5423b1c 108 Gene3D G3DSA:3.40.30.10 2 107 1.1E-39 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS01785 762892876de44db6a38e0927ba8bf25c 451 SUPERFAMILY SSF161093 280 450 1.19E-42 T 05-07-2017 K08M4_RS01785 762892876de44db6a38e0927ba8bf25c 451 SMART SM00924 36 139 2.6E-35 T 05-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain K08M4_RS01785 762892876de44db6a38e0927ba8bf25c 451 Gene3D G3DSA:1.25.60.10 9 129 3.7E-28 T 05-07-2017 K08M4_RS01785 762892876de44db6a38e0927ba8bf25c 451 SUPERFAMILY SSF54631 139 278 2.27E-27 T 05-07-2017 K08M4_RS01785 762892876de44db6a38e0927ba8bf25c 451 Pfam PF03448 MgtE intracellular N domain 36 137 7.8E-26 T 05-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain K08M4_RS01785 762892876de44db6a38e0927ba8bf25c 451 Pfam PF01769 Divalent cation transporter 323 445 7.4E-22 T 05-07-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 K08M4_RS01785 762892876de44db6a38e0927ba8bf25c 451 SMART SM00116 212 258 0.15 T 05-07-2017 IPR000644 CBS domain K08M4_RS01785 762892876de44db6a38e0927ba8bf25c 451 SMART SM00116 146 199 30.0 T 05-07-2017 IPR000644 CBS domain K08M4_RS01785 762892876de44db6a38e0927ba8bf25c 451 Gene3D G3DSA:3.10.580.10 130 262 3.4E-17 T 05-07-2017 K08M4_RS01785 762892876de44db6a38e0927ba8bf25c 451 Pfam PF00571 CBS domain 139 196 2.2E-4 T 05-07-2017 IPR000644 CBS domain K08M4_RS01785 762892876de44db6a38e0927ba8bf25c 451 Pfam PF00571 CBS domain 204 257 1.2E-5 T 05-07-2017 IPR000644 CBS domain K08M4_RS01785 762892876de44db6a38e0927ba8bf25c 451 TIGRFAM TIGR00400 mgtE: magnesium transporter 20 451 2.3E-86 T 05-07-2017 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 K08M4_RS01785 762892876de44db6a38e0927ba8bf25c 451 SUPERFAMILY SSF158791 11 136 5.1E-30 T 05-07-2017 K08M4_RS01785 762892876de44db6a38e0927ba8bf25c 451 Gene3D G3DSA:1.10.357.20 280 451 7.0E-47 T 05-07-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 K08M4_RS01745 42c902c3881f8aad34337f82fd53b3dc 336 SUPERFAMILY SSF56655 3 331 4.65E-113 T 05-07-2017 K08M4_RS01745 42c902c3881f8aad34337f82fd53b3dc 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 151 174 3.6E-77 T 05-07-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 K08M4_RS01745 42c902c3881f8aad34337f82fd53b3dc 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 67 93 3.6E-77 T 05-07-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 K08M4_RS01745 42c902c3881f8aad34337f82fd53b3dc 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 182 205 3.6E-77 T 05-07-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 K08M4_RS01745 42c902c3881f8aad34337f82fd53b3dc 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 30 57 3.6E-77 T 05-07-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 K08M4_RS01745 42c902c3881f8aad34337f82fd53b3dc 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 307 332 3.6E-77 T 05-07-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 K08M4_RS01745 42c902c3881f8aad34337f82fd53b3dc 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 208 235 3.6E-77 T 05-07-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 K08M4_RS01745 42c902c3881f8aad34337f82fd53b3dc 336 PIRSF PIRSF000904 1 336 8.8E-126 T 05-07-2017 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 K08M4_RS01745 42c902c3881f8aad34337f82fd53b3dc 336 PIRSF PIRSF500210 1 336 1.8E-128 T 05-07-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 K08M4_RS01745 42c902c3881f8aad34337f82fd53b3dc 336 Gene3D G3DSA:3.40.190.80 199 331 2.0E-59 T 05-07-2017 K08M4_RS01745 42c902c3881f8aad34337f82fd53b3dc 336 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 6 197 5.9E-77 T 05-07-2017 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 K08M4_RS01745 42c902c3881f8aad34337f82fd53b3dc 336 ProSitePatterns PS00124 Fructose-1-6-bisphosphatase active site. 273 285 - T 05-07-2017 IPR020548 Fructose-1,6-bisphosphatase, active site GO:0005975|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 K08M4_RS01745 42c902c3881f8aad34337f82fd53b3dc 336 Gene3D G3DSA:3.30.540.10 5 198 5.8E-80 T 05-07-2017 K08M4_RS01745 42c902c3881f8aad34337f82fd53b3dc 336 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 5 333 42.852 T 05-07-2017 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 SUPERFAMILY SSF82714 716 800 1.03E-17 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 SUPERFAMILY SSF82714 185 269 5.1E-17 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 SUPERFAMILY SSF82693 271 328 7.85E-23 T 05-07-2017 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 SUPERFAMILY SSF82693 137 184 7.85E-23 T 05-07-2017 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 SUPERFAMILY SSF82693 46 127 4.71E-20 T 05-07-2017 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1043 0.0 T 05-07-2017 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 SUPERFAMILY SSF82866 798 1037 7.32E-50 T 05-07-2017 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 PRINTS PR00702 Acriflavin resistance protein family signature 545 562 3.0E-33 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 3.0E-33 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 3.0E-33 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 3.0E-33 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 3.0E-33 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 3.0E-33 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 3.0E-33 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 Pfam PF00873 AcrB/AcrD/AcrF family 5 1032 3.4E-244 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 Gene3D G3DSA:3.30.2090.10 717 800 4.9E-19 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 Gene3D G3DSA:3.30.2090.10 185 269 3.5E-18 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 Gene3D G3DSA:1.10.3850.10 806 1035 1.4E-51 T 05-07-2017 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 Gene3D G3DSA:1.10.3850.10 278 499 6.6E-68 T 05-07-2017 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 Gene3D G3DSA:3.30.70.1430 46 142 2.0E-24 T 05-07-2017 K08M4_RS17520 5aa78ac70a5be83ffd761abd9801a64b 1047 SUPERFAMILY SSF82866 294 498 1.31E-42 T 05-07-2017 K08M4_RS18815 88af40097de4b03148dc8a7d3e72c5f5 600 SUPERFAMILY SSF52540 1 166 3.18E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18815 88af40097de4b03148dc8a7d3e72c5f5 600 SUPERFAMILY SSF52540 271 383 3.18E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18815 88af40097de4b03148dc8a7d3e72c5f5 600 Gene3D G3DSA:3.40.50.300 1 180 1.6E-28 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18815 88af40097de4b03148dc8a7d3e72c5f5 600 Gene3D G3DSA:3.40.50.300 232 405 1.6E-28 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18815 88af40097de4b03148dc8a7d3e72c5f5 600 Pfam PF11398 Protein of unknown function (DUF2813) 1 174 3.3E-64 T 05-07-2017 IPR022602 Protein of unknown function DUF2813 K08M4_RS18815 88af40097de4b03148dc8a7d3e72c5f5 600 Pfam PF11398 Protein of unknown function (DUF2813) 227 426 1.1E-73 T 05-07-2017 IPR022602 Protein of unknown function DUF2813 K08M4_RS18815 88af40097de4b03148dc8a7d3e72c5f5 600 Gene3D G3DSA:3.40.1360.10 432 534 6.6E-5 T 05-07-2017 K08M4_RS07450 c1a04e7e8c4e58e00a257ac838eb281e 302 Pfam PF00480 ROK family 2 300 6.2E-71 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 K08M4_RS07450 c1a04e7e8c4e58e00a257ac838eb281e 302 SUPERFAMILY SSF53067 1 299 5.72E-58 T 05-07-2017 K08M4_RS07450 c1a04e7e8c4e58e00a257ac838eb281e 302 Gene3D G3DSA:3.30.420.40 133 280 3.7E-44 T 05-07-2017 K08M4_RS07450 c1a04e7e8c4e58e00a257ac838eb281e 302 Gene3D G3DSA:3.30.420.40 1 132 8.3E-37 T 05-07-2017 K08M4_RS07450 c1a04e7e8c4e58e00a257ac838eb281e 302 ProSitePatterns PS01125 ROK family signature. 130 157 - T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 K08M4_RS07450 c1a04e7e8c4e58e00a257ac838eb281e 302 Hamap MF_01271 N-acetyl-D-glucosamine kinase [nagK]. 1 302 63.161 T 05-07-2017 IPR023505 N-acetyl-D-glucosamine kinase GO:0045127 KEGG: 00520+2.7.1.59|MetaCyc: PWY-6517|MetaCyc: PWY-6906 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 Gene3D G3DSA:2.40.37.10 213 358 1.1E-56 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 Gene3D G3DSA:3.20.20.10 10 212 4.0E-70 T 05-07-2017 IPR029066 PLP-binding barrel K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 TIGRFAM TIGR00492 alr: alanine racemase 3 357 4.1E-129 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 31 41 - T 05-07-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 Pfam PF01168 Alanine racemase, N-terminal domain 8 219 5.7E-67 T 05-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 Hamap MF_01201 Alanine racemase. 1 357 34.96 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 SUPERFAMILY SSF50621 227 357 1.01E-46 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 PRINTS PR00992 Alanine racemase signature 60 78 7.5E-71 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 PRINTS PR00992 Alanine racemase signature 287 304 7.5E-71 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 PRINTS PR00992 Alanine racemase signature 339 352 7.5E-71 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 PRINTS PR00992 Alanine racemase signature 249 264 7.5E-71 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 PRINTS PR00992 Alanine racemase signature 192 219 7.5E-71 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 PRINTS PR00992 Alanine racemase signature 120 132 7.5E-71 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 PRINTS PR00992 Alanine racemase signature 26 42 7.5E-71 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 PRINTS PR00992 Alanine racemase signature 266 281 7.5E-71 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 PRINTS PR00992 Alanine racemase signature 155 166 7.5E-71 T 05-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 Pfam PF00842 Alanine racemase, C-terminal domain 233 356 9.4E-40 T 05-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 SMART SM01005 233 357 4.2E-69 T 05-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS13445 23bce4e7b32289aa915bccc09d9faf8b 358 SUPERFAMILY SSF51419 8 234 2.04E-68 T 05-07-2017 IPR029066 PLP-binding barrel K08M4_RS11855 1f70a45e4aafaf81e115ef3e5cf1af69 380 SUPERFAMILY SSF102114 100 319 3.14E-14 T 05-07-2017 K08M4_RS11855 1f70a45e4aafaf81e115ef3e5cf1af69 380 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 5 353 71.451 T 05-07-2017 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS11855 1f70a45e4aafaf81e115ef3e5cf1af69 380 PIRSF PIRSF006004 3 367 1.9E-140 T 05-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS11855 1f70a45e4aafaf81e115ef3e5cf1af69 380 SMART SM00729 104 325 0.008 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 K08M4_RS11855 1f70a45e4aafaf81e115ef3e5cf1af69 380 Gene3D G3DSA:3.20.20.70 106 330 8.6E-16 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS11855 1f70a45e4aafaf81e115ef3e5cf1af69 380 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 3 358 2.4E-153 T 05-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS11855 1f70a45e4aafaf81e115ef3e5cf1af69 380 Pfam PF04055 Radical SAM superfamily 109 283 1.5E-14 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS03845 dd734797582412726177de5f0c8403e0 379 SUPERFAMILY SSF55174 8 99 4.21E-15 T 05-07-2017 K08M4_RS03845 dd734797582412726177de5f0c8403e0 379 SMART SM00363 8 67 2.0E-9 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS03845 dd734797582412726177de5f0c8403e0 379 Pfam PF01479 S4 domain 9 53 9.1E-11 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS03845 dd734797582412726177de5f0c8403e0 379 Pfam PF00849 RNA pseudouridylate synthase 68 194 6.5E-13 T 05-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS03845 dd734797582412726177de5f0c8403e0 379 Gene3D G3DSA:3.10.290.10 8 68 7.5E-24 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS03845 dd734797582412726177de5f0c8403e0 379 SUPERFAMILY SSF55120 67 228 1.55E-38 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS03845 dd734797582412726177de5f0c8403e0 379 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 72 224 9.5E-48 T 05-07-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 K08M4_RS03845 dd734797582412726177de5f0c8403e0 379 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 103 117 - T 05-07-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 K08M4_RS19285 06a72760cb5d74c822e9ce8da9cce425 165 SMART SM00554 66 165 8.5E-34 T 05-07-2017 IPR000782 FAS1 domain K08M4_RS19285 06a72760cb5d74c822e9ce8da9cce425 165 Gene3D G3DSA:2.30.180.10 31 164 8.6E-46 T 05-07-2017 IPR000782 FAS1 domain K08M4_RS19285 06a72760cb5d74c822e9ce8da9cce425 165 Pfam PF02469 Fasciclin domain 42 164 1.9E-37 T 05-07-2017 IPR000782 FAS1 domain K08M4_RS19285 06a72760cb5d74c822e9ce8da9cce425 165 SUPERFAMILY SSF82153 31 164 9.81E-45 T 05-07-2017 IPR000782 FAS1 domain K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 Pfam PF05524 PEP-utilising enzyme, N-terminal 4 126 9.7E-31 T 05-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 447 465 - T 05-07-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 SUPERFAMILY SSF52009 125 243 1.57E-34 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 Gene3D G3DSA:3.50.30.10 133 255 4.7E-38 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 447 462 6.9E-30 T 05-07-2017 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 293 312 6.9E-30 T 05-07-2017 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 500 512 6.9E-30 T 05-07-2017 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 464 479 6.9E-30 T 05-07-2017 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 SUPERFAMILY SSF51621 250 549 2.09E-107 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 2 565 2.5E-242 T 05-07-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 184 195 - T 05-07-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 Pfam PF00391 PEP-utilising enzyme, mobile domain 152 222 3.5E-20 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 251 541 4.1E-122 T 05-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 Gene3D G3DSA:3.20.20.60 256 571 1.6E-111 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 Gene3D G3DSA:1.10.274.10 23 132 1.0E-35 T 05-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 PIRSF PIRSF000732 1 574 8.1E-217 T 05-07-2017 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 K08M4_RS10910 c0a846f394a1b2c82e3537f7511fef36 574 SUPERFAMILY SSF47831 24 143 6.15E-32 T 05-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 K08M4_RS05820 06a2a8f419c6f415397a5e04bb6b179b 148 Pfam PF03724 META domain 34 138 3.0E-26 T 05-07-2017 IPR005184 Domain of unknown function DUF306, Meta/HslJ K08M4_RS06885 c76fe53ca6a7ac46d0af1fd959387fdf 138 SUPERFAMILY SSF46785 4 137 6.34E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06885 c76fe53ca6a7ac46d0af1fd959387fdf 138 SMART SM00347 24 124 4.3E-22 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS06885 c76fe53ca6a7ac46d0af1fd959387fdf 138 Gene3D G3DSA:1.10.10.10 3 137 7.1E-35 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06885 c76fe53ca6a7ac46d0af1fd959387fdf 138 Pfam PF01047 MarR family 32 88 1.2E-14 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS06885 c76fe53ca6a7ac46d0af1fd959387fdf 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 6.4E-11 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS06885 c76fe53ca6a7ac46d0af1fd959387fdf 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 6.4E-11 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS06885 c76fe53ca6a7ac46d0af1fd959387fdf 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 6.4E-11 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS06885 c76fe53ca6a7ac46d0af1fd959387fdf 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 6.4E-11 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS11615 d556234585b9c0750877f4d5b3caf29e 329 Pfam PF14057 GGGtGRT protein 8 325 2.2E-177 T 05-07-2017 IPR025964 GGGtGRT protein K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 Gene3D G3DSA:1.10.150.80 535 606 2.5E-22 T 05-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 Pfam PF00271 Helicase conserved C-terminal domain 231 335 1.0E-19 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 SMART SM00487 26 222 3.9E-26 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 SUPERFAMILY SSF47819 535 610 1.46E-25 T 05-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 SMART SM00490 254 335 2.7E-29 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 Gene3D G3DSA:1.10.10.10 349 518 2.9E-62 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 SUPERFAMILY SSF52540 212 461 2.07E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 Gene3D G3DSA:3.40.50.300 211 348 1.2E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 Pfam PF16124 RecQ zinc-binding 347 408 2.6E-18 T 05-07-2017 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 Pfam PF09382 RQC domain 410 518 3.2E-37 T 05-07-2017 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 Gene3D G3DSA:3.40.50.300 18 206 2.1E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 20 467 1.2E-188 T 05-07-2017 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 SUPERFAMILY SSF52540 18 203 2.45E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 Pfam PF00270 DEAD/DEAH box helicase 32 191 1.2E-18 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 Pfam PF00570 HRDC domain 538 604 4.0E-22 T 05-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 17 607 2.9E-253 T 05-07-2017 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 SMART SM00341 534 610 4.2E-22 T 05-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 K08M4_RS00260 cbb2b80a704e178c31988bbcd9b35b78 612 SMART SM00956 415 518 1.5E-50 T 05-07-2017 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 K08M4_RS18650 3b01db7a418d504cf28ec4720fe50029 206 SUPERFAMILY SSF46565 115 204 1.31E-12 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS18650 3b01db7a418d504cf28ec4720fe50029 206 Gene3D G3DSA:1.10.287.110 157 204 5.4E-12 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS18650 3b01db7a418d504cf28ec4720fe50029 206 Pfam PF12339 DNA-J related protein 17 139 6.7E-42 T 05-07-2017 IPR021059 DnaJ-related protein, N-terminal K08M4_RS18650 3b01db7a418d504cf28ec4720fe50029 206 SMART SM00271 153 206 2.7E-7 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS18650 3b01db7a418d504cf28ec4720fe50029 206 Pfam PF00226 DnaJ domain 160 204 1.7E-10 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS09020 85f70eb6dbe16e734164ee74e4efb9e9 362 SUPERFAMILY SSF50969 64 313 1.96E-13 T 05-07-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like K08M4_RS09020 85f70eb6dbe16e734164ee74e4efb9e9 362 Gene3D G3DSA:2.130.10.10 64 185 2.1E-8 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 K08M4_RS09020 85f70eb6dbe16e734164ee74e4efb9e9 362 Gene3D G3DSA:2.130.10.10 232 233 2.1E-8 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 K08M4_RS09020 85f70eb6dbe16e734164ee74e4efb9e9 362 Gene3D G3DSA:2.130.10.10 278 311 2.1E-8 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 K08M4_RS09020 85f70eb6dbe16e734164ee74e4efb9e9 362 Pfam PF07433 Protein of unknown function (DUF1513) 69 361 2.7E-107 T 05-07-2017 IPR008311 Uncharacterised conserved protein UCP028101 K08M4_RS09020 85f70eb6dbe16e734164ee74e4efb9e9 362 PIRSF PIRSF028101 1 362 1.5E-145 T 05-07-2017 IPR008311 Uncharacterised conserved protein UCP028101 K08M4_RS12015 b2e1cc834adedfe158c22e286b371304 738 SUPERFAMILY SSF69322 60 364 3.92E-8 T 05-07-2017 K08M4_RS12015 b2e1cc834adedfe158c22e286b371304 738 Gene3D G3DSA:1.10.3720.10 575 736 3.4E-49 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS12015 b2e1cc834adedfe158c22e286b371304 738 Gene3D G3DSA:1.10.3720.10 30 56 3.4E-49 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS12015 b2e1cc834adedfe158c22e286b371304 738 Gene3D G3DSA:1.10.3720.10 420 502 3.4E-49 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS12015 b2e1cc834adedfe158c22e286b371304 738 SUPERFAMILY SSF161098 582 727 9.35E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS12015 b2e1cc834adedfe158c22e286b371304 738 SUPERFAMILY SSF161098 430 505 9.35E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS12015 b2e1cc834adedfe158c22e286b371304 738 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 456 732 5.2E-10 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS09560 0be18814f3261e0084f86e03845f1d03 311 Pfam PF00155 Aminotransferase class I and II 2 274 4.8E-44 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS09560 0be18814f3261e0084f86e03845f1d03 311 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 131 140 - T 05-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 K08M4_RS09560 0be18814f3261e0084f86e03845f1d03 311 Gene3D G3DSA:3.90.1150.10 168 275 1.6E-20 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS09560 0be18814f3261e0084f86e03845f1d03 311 Gene3D G3DSA:3.40.640.10 1 167 3.1E-65 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS09560 0be18814f3261e0084f86e03845f1d03 311 SUPERFAMILY SSF53383 2 281 8.11E-72 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS17585 6c77c4c2894d65dd0ee10c330117ebb4 248 SMART SM00382 36 219 8.9E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS17585 6c77c4c2894d65dd0ee10c330117ebb4 248 Pfam PF00005 ABC transporter 27 171 2.6E-33 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS17585 6c77c4c2894d65dd0ee10c330117ebb4 248 Gene3D G3DSA:3.40.50.300 10 243 1.6E-81 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17585 6c77c4c2894d65dd0ee10c330117ebb4 248 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS17585 6c77c4c2894d65dd0ee10c330117ebb4 248 SUPERFAMILY SSF52540 11 241 6.69E-78 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17585 6c77c4c2894d65dd0ee10c330117ebb4 248 PIRSF PIRSF039085 8 247 2.2E-103 T 05-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 K08M4_RS09070 76defcfb3a6f2ca2daa7557b3d6d74eb 194 Gene3D G3DSA:1.10.3820.10 8 192 1.1E-19 T 05-07-2017 K08M4_RS09070 76defcfb3a6f2ca2daa7557b3d6d74eb 194 SUPERFAMILY SSF48695 5 189 9.99E-29 T 05-07-2017 IPR011031 Multihaem cytochrome K08M4_RS09070 76defcfb3a6f2ca2daa7557b3d6d74eb 194 TIGRFAM TIGR03146 cyt_nit_nrfB: cytochrome c nitrite reductase, pentaheme subunit 41 188 3.0E-62 T 05-07-2017 IPR017564 Cytochrome c nitrite reductase, pentahaem subunit GO:0006807|GO:0020037|GO:0042597 K08M4_RS09070 76defcfb3a6f2ca2daa7557b3d6d74eb 194 Pfam PF09699 Doubled CXXCH motif (Paired_CXXCH_1) 154 187 8.4E-6 T 05-07-2017 IPR010177 Doubled CXXCH motif K08M4_RS00445 4742a6c78bb04ec65e95c6758046a729 832 Pfam PF00563 EAL domain 602 828 4.6E-59 T 05-07-2017 IPR001633 EAL domain K08M4_RS00445 4742a6c78bb04ec65e95c6758046a729 832 SMART SM01204 217 343 8.2E-18 T 05-07-2017 IPR019494 FIST, C-domain K08M4_RS00445 4742a6c78bb04ec65e95c6758046a729 832 Pfam PF08495 FIST N domain 30 215 8.3E-20 T 05-07-2017 IPR013702 FIST domain, N-terminal K08M4_RS00445 4742a6c78bb04ec65e95c6758046a729 832 Gene3D G3DSA:3.30.70.270 417 526 9.7E-9 T 05-07-2017 K08M4_RS00445 4742a6c78bb04ec65e95c6758046a729 832 SUPERFAMILY SSF141868 602 828 2.22E-58 T 05-07-2017 IPR001633 EAL domain K08M4_RS00445 4742a6c78bb04ec65e95c6758046a729 832 Pfam PF10442 FIST C domain 217 341 3.6E-13 T 05-07-2017 IPR019494 FIST, C-domain K08M4_RS00445 4742a6c78bb04ec65e95c6758046a729 832 SMART SM00052 595 832 4.2E-32 T 05-07-2017 IPR001633 EAL domain K08M4_RS00445 4742a6c78bb04ec65e95c6758046a729 832 Gene3D G3DSA:3.20.20.450 603 829 4.7E-59 T 05-07-2017 IPR001633 EAL domain K08M4_RS00445 4742a6c78bb04ec65e95c6758046a729 832 SMART SM00897 27 216 1.7E-21 T 05-07-2017 IPR013702 FIST domain, N-terminal K08M4_RS00445 4742a6c78bb04ec65e95c6758046a729 832 Pfam PF00990 Diguanylate cyclase, GGDEF domain 417 473 1.5E-7 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS00445 4742a6c78bb04ec65e95c6758046a729 832 SUPERFAMILY SSF55073 421 477 6.91E-8 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS08870 a110f65f70868d12a58216d7c44bb8fc 285 Gene3D G3DSA:1.10.443.10 103 262 1.6E-42 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS08870 a110f65f70868d12a58216d7c44bb8fc 285 Pfam PF00589 Phage integrase family 103 260 2.0E-33 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS08870 a110f65f70868d12a58216d7c44bb8fc 285 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 86 5.7E-20 T 05-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 K08M4_RS08870 a110f65f70868d12a58216d7c44bb8fc 285 SUPERFAMILY SSF56349 7 262 8.24E-46 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS08870 a110f65f70868d12a58216d7c44bb8fc 285 Gene3D G3DSA:1.10.150.130 5 83 8.3E-5 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal K08M4_RS19040 a110f65f70868d12a58216d7c44bb8fc 285 Gene3D G3DSA:1.10.443.10 103 262 1.6E-42 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS19040 a110f65f70868d12a58216d7c44bb8fc 285 Pfam PF00589 Phage integrase family 103 260 2.0E-33 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS19040 a110f65f70868d12a58216d7c44bb8fc 285 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 86 5.7E-20 T 05-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 K08M4_RS19040 a110f65f70868d12a58216d7c44bb8fc 285 SUPERFAMILY SSF56349 7 262 8.24E-46 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS19040 a110f65f70868d12a58216d7c44bb8fc 285 Gene3D G3DSA:1.10.150.130 5 83 8.3E-5 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal K08M4_RS08860 a110f65f70868d12a58216d7c44bb8fc 285 Gene3D G3DSA:1.10.443.10 103 262 1.6E-42 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS08860 a110f65f70868d12a58216d7c44bb8fc 285 Pfam PF00589 Phage integrase family 103 260 2.0E-33 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS08860 a110f65f70868d12a58216d7c44bb8fc 285 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 86 5.7E-20 T 05-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 K08M4_RS08860 a110f65f70868d12a58216d7c44bb8fc 285 SUPERFAMILY SSF56349 7 262 8.24E-46 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS08860 a110f65f70868d12a58216d7c44bb8fc 285 Gene3D G3DSA:1.10.150.130 5 83 8.3E-5 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal K08M4_RS20555 d7e5245bbe351dbdfae7fb8a6c11ea20 326 Gene3D G3DSA:3.40.50.720 1 144 9.7E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS20555 d7e5245bbe351dbdfae7fb8a6c11ea20 326 Gene3D G3DSA:3.30.360.10 145 326 2.7E-64 T 05-07-2017 K08M4_RS20555 d7e5245bbe351dbdfae7fb8a6c11ea20 326 SUPERFAMILY SSF55347 137 290 1.64E-22 T 05-07-2017 K08M4_RS20555 d7e5245bbe351dbdfae7fb8a6c11ea20 326 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 120 6.1E-29 T 05-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 K08M4_RS20555 d7e5245bbe351dbdfae7fb8a6c11ea20 326 SUPERFAMILY SSF51735 2 152 3.21E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS16640 ca4adc9b59a6a8a72eb4c6d4127b565f 478 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 286 293 - T 05-07-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS16640 ca4adc9b59a6a8a72eb4c6d4127b565f 478 SMART SM00846 127 288 6.0E-56 T 05-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS16640 ca4adc9b59a6a8a72eb4c6d4127b565f 478 Gene3D G3DSA:3.40.50.720 127 296 2.1E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS16640 ca4adc9b59a6a8a72eb4c6d4127b565f 478 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 129 462 2.5E-112 T 05-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS16640 ca4adc9b59a6a8a72eb4c6d4127b565f 478 Gene3D G3DSA:3.30.360.10 297 452 4.1E-53 T 05-07-2017 K08M4_RS16640 ca4adc9b59a6a8a72eb4c6d4127b565f 478 SUPERFAMILY SSF55347 288 451 1.37E-52 T 05-07-2017 K08M4_RS16640 ca4adc9b59a6a8a72eb4c6d4127b565f 478 SUPERFAMILY SSF51735 128 304 2.1E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS16640 ca4adc9b59a6a8a72eb4c6d4127b565f 478 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 128 288 3.1E-39 T 05-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS16640 ca4adc9b59a6a8a72eb4c6d4127b565f 478 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 246 259 5.7E-18 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS16640 ca4adc9b59a6a8a72eb4c6d4127b565f 478 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 365 382 5.7E-18 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS16640 ca4adc9b59a6a8a72eb4c6d4127b565f 478 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 282 300 5.7E-18 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS16640 ca4adc9b59a6a8a72eb4c6d4127b565f 478 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 309 325 5.7E-18 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS16640 ca4adc9b59a6a8a72eb4c6d4127b565f 478 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 293 450 2.3E-44 T 05-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 Pfam PF00403 Heavy-metal-associated domain 178 235 3.9E-13 T 05-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 SUPERFAMILY SSF55008 77 139 4.97E-8 T 05-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 SUPERFAMILY SSF55008 171 241 2.62E-15 T 05-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 Gene3D G3DSA:3.30.70.100 78 138 3.3E-8 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 Pfam PF00122 E1-E2 ATPase 367 588 1.6E-61 T 05-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 329 905 6.8E-184 T 05-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 Gene3D G3DSA:2.70.150.10 342 497 4.0E-31 T 05-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 Gene3D G3DSA:3.30.70.100 172 256 1.7E-19 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 ProSitePatterns PS01047 Heavy-metal-associated domain. 177 206 - T 05-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 SUPERFAMILY SSF81665 343 400 1.57E-10 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 SUPERFAMILY SSF81665 497 592 1.57E-10 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 Pfam PF00702 haloacid dehalogenase-like hydrolase 594 810 3.8E-44 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 311 906 4.4E-184 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 SUPERFAMILY SSF56784 654 902 4.12E-57 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 SUPERFAMILY SSF56784 597 616 4.12E-57 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 600 606 - T 05-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 Gene3D G3DSA:3.40.1110.10 630 723 6.4E-15 T 05-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 PRINTS PR00943 Copper-transporting ATPase signature 187 201 5.4E-12 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 PRINTS PR00943 Copper-transporting ATPase signature 830 844 5.4E-12 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 PRINTS PR00943 Copper-transporting ATPase signature 519 533 5.4E-12 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 PRINTS PR00943 Copper-transporting ATPase signature 773 790 5.4E-12 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 PRINTS PR00943 Copper-transporting ATPase signature 581 596 5.4E-12 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 PRINTS PR00943 Copper-transporting ATPase signature 314 333 5.4E-12 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 PRINTS PR00943 Copper-transporting ATPase signature 386 404 5.4E-12 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 SUPERFAMILY SSF81653 399 496 7.85E-27 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 796 815 2.3E-26 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 598 612 2.3E-26 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 721 732 2.3E-26 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 819 831 2.3E-26 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 743 753 2.3E-26 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 446 460 2.3E-26 T 05-07-2017 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 Gene3D G3DSA:3.40.1110.10 605 629 2.0E-4 T 05-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 Gene3D G3DSA:3.40.50.1000 724 864 9.7E-55 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 Gene3D G3DSA:3.40.50.1000 570 604 9.7E-55 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS03885 c5cea27facd2430e46c94a03e9c343d2 927 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 368 873 2.0E-87 T 05-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 K08M4_RS17665 31ff2ddad1898d104c188581ba7713bd 394 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 164 5.5E-16 T 05-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 K08M4_RS17665 31ff2ddad1898d104c188581ba7713bd 394 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 68 79 5.5E-16 T 05-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 K08M4_RS17665 31ff2ddad1898d104c188581ba7713bd 394 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 5.5E-16 T 05-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 K08M4_RS17665 31ff2ddad1898d104c188581ba7713bd 394 Gene3D G3DSA:3.40.710.10 34 284 1.9E-93 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS17665 31ff2ddad1898d104c188581ba7713bd 394 SUPERFAMILY SSF56601 17 285 2.82E-80 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS17665 31ff2ddad1898d104c188581ba7713bd 394 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 285 375 3.1E-22 T 05-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 K08M4_RS17665 31ff2ddad1898d104c188581ba7713bd 394 SUPERFAMILY SSF69189 285 377 7.85E-23 T 05-07-2017 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 K08M4_RS17665 31ff2ddad1898d104c188581ba7713bd 394 SMART SM00936 285 375 2.9E-30 T 05-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 K08M4_RS17665 31ff2ddad1898d104c188581ba7713bd 394 Gene3D G3DSA:2.60.410.10 285 375 4.4E-26 T 05-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 K08M4_RS17665 31ff2ddad1898d104c188581ba7713bd 394 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 35 265 8.3E-85 T 05-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 K08M4_RS19555 1a9eff32edf9649924f4b8ca2dbc19f6 586 SUPERFAMILY SSF52794 2 102 3.66E-27 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS19555 1a9eff32edf9649924f4b8ca2dbc19f6 586 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 243 573 3.7E-137 T 05-07-2017 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 K08M4_RS19555 1a9eff32edf9649924f4b8ca2dbc19f6 586 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 134 222 3.4E-16 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS19555 1a9eff32edf9649924f4b8ca2dbc19f6 586 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 95 2.0E-12 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS19555 1a9eff32edf9649924f4b8ca2dbc19f6 586 Pfam PF02378 Phosphotransferase system, EIIC 256 519 1.1E-15 T 05-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 K08M4_RS19555 1a9eff32edf9649924f4b8ca2dbc19f6 586 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 133 216 3.3E-35 T 05-07-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 K08M4_RS19555 1a9eff32edf9649924f4b8ca2dbc19f6 586 SUPERFAMILY SSF52794 131 232 1.26E-36 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS19555 1a9eff32edf9649924f4b8ca2dbc19f6 586 Gene3D G3DSA:3.40.50.2300 127 233 1.6E-43 T 05-07-2017 K08M4_RS19555 1a9eff32edf9649924f4b8ca2dbc19f6 586 Gene3D G3DSA:3.40.50.2300 1 102 1.1E-27 T 05-07-2017 K08M4_RS10585 89524c41c85c509e8fb2f09edc9d05eb 115 SUPERFAMILY SSF81343 3 114 9.81E-28 T 05-07-2017 K08M4_RS10585 89524c41c85c509e8fb2f09edc9d05eb 115 PIRSF PIRSF000169 1 115 2.7E-39 T 05-07-2017 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 K08M4_RS10585 89524c41c85c509e8fb2f09edc9d05eb 115 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 11 102 4.0E-6 T 05-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS10585 89524c41c85c509e8fb2f09edc9d05eb 115 Gene3D G3DSA:1.20.1300.10 1 114 7.2E-37 T 05-07-2017 K08M4_RS10585 89524c41c85c509e8fb2f09edc9d05eb 115 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 10 113 2.5E-35 T 05-07-2017 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 K08M4_RS08600 438d5ef38b5861903f9c6c896c060a0d 420 Pfam PF06097 Bacterial protein of unknown function (DUF945) 9 410 6.7E-42 T 05-07-2017 IPR010352 Protein of unknown function DUF945 K08M4_RS07925 0c1dea39381808642829a61799c2123e 109 Gene3D G3DSA:1.10.10.370 40 109 2.3E-35 T 05-07-2017 K08M4_RS07925 0c1dea39381808642829a61799c2123e 109 PIRSF PIRSF006223 2 109 2.4E-40 T 05-07-2017 IPR007453 Sulphur transfer protein DsrC/TusE K08M4_RS07925 0c1dea39381808642829a61799c2123e 109 Pfam PF04358 DsrC like protein 3 109 2.3E-43 T 05-07-2017 IPR007453 Sulphur transfer protein DsrC/TusE K08M4_RS07925 0c1dea39381808642829a61799c2123e 109 Gene3D G3DSA:3.30.1420.10 1 39 1.3E-13 T 05-07-2017 K08M4_RS07925 0c1dea39381808642829a61799c2123e 109 SUPERFAMILY SSF69721 2 109 2.22E-40 T 05-07-2017 IPR025526 DsrC-like domain K08M4_RS07925 0c1dea39381808642829a61799c2123e 109 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 3 109 1.0E-48 T 05-07-2017 IPR007453 Sulphur transfer protein DsrC/TusE K08M4_RS21690 4ea0e7e0910b0042a36f2a8a4c59b78b 599 Pfam PF07549 SecD/SecF GG Motif 124 146 2.0E-5 T 05-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site K08M4_RS21690 4ea0e7e0910b0042a36f2a8a4c59b78b 599 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 130 585 3.3E-127 T 05-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 K08M4_RS21690 4ea0e7e0910b0042a36f2a8a4c59b78b 599 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 13 599 45.384 T 05-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 K08M4_RS21690 4ea0e7e0910b0042a36f2a8a4c59b78b 599 SUPERFAMILY SSF82866 393 591 2.49E-38 T 05-07-2017 K08M4_RS21690 4ea0e7e0910b0042a36f2a8a4c59b78b 599 Pfam PF02355 Protein export membrane protein 417 586 9.4E-19 T 05-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial K08M4_RS21690 4ea0e7e0910b0042a36f2a8a4c59b78b 599 Pfam PF13721 SecD export protein N-terminal TM region 12 110 1.6E-24 T 05-07-2017 IPR027398 SecD export protein N-terminal TM domain K08M4_RS21690 4ea0e7e0910b0042a36f2a8a4c59b78b 599 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 335 578 3.6E-73 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS21690 4ea0e7e0910b0042a36f2a8a4c59b78b 599 Gene3D G3DSA:1.20.1640.10 394 592 1.7E-21 T 05-07-2017 K08M4_RS02410 0a268b2c0aa9b0c902a9b44be728e788 86 Pfam PF03937 Flavinator of succinate dehydrogenase 7 77 4.3E-24 T 05-07-2017 IPR005631 Flavinator of succinate dehydrogenase K08M4_RS02410 0a268b2c0aa9b0c902a9b44be728e788 86 Gene3D G3DSA:1.10.150.250 3 83 3.3E-29 T 05-07-2017 IPR005631 Flavinator of succinate dehydrogenase K08M4_RS02410 0a268b2c0aa9b0c902a9b44be728e788 86 SUPERFAMILY SSF109910 3 79 8.11E-26 T 05-07-2017 IPR005631 Flavinator of succinate dehydrogenase K08M4_RS14225 6f90d52dadc0f13ba667e825d570b0cb 197 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 30 2.6E-6 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS14225 6f90d52dadc0f13ba667e825d570b0cb 197 SUPERFAMILY SSF54523 10 81 1.57E-7 T 05-07-2017 K08M4_RS14225 6f90d52dadc0f13ba667e825d570b0cb 197 PRINTS PR00885 Bacterial general secretion pathway protein H signature 146 161 1.2E-20 T 05-07-2017 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 K08M4_RS14225 6f90d52dadc0f13ba667e825d570b0cb 197 PRINTS PR00885 Bacterial general secretion pathway protein H signature 20 34 1.2E-20 T 05-07-2017 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 K08M4_RS14225 6f90d52dadc0f13ba667e825d570b0cb 197 PRINTS PR00885 Bacterial general secretion pathway protein H signature 5 19 1.2E-20 T 05-07-2017 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 K08M4_RS14225 6f90d52dadc0f13ba667e825d570b0cb 197 Pfam PF12019 Type II transport protein GspH 45 183 2.7E-7 T 05-07-2017 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 K08M4_RS14225 6f90d52dadc0f13ba667e825d570b0cb 197 Gene3D G3DSA:3.55.40.10 41 195 3.5E-49 T 05-07-2017 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 K08M4_RS16970 bac5af1961b90ed34af70286cb903773 456 SUPERFAMILY SSF143548 16 155 1.26E-43 T 05-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 K08M4_RS16970 bac5af1961b90ed34af70286cb903773 456 Pfam PF03313 Serine dehydratase alpha chain 183 447 9.3E-95 T 05-07-2017 IPR005130 Serine dehydratase-like, alpha subunit K08M4_RS16970 bac5af1961b90ed34af70286cb903773 456 Pfam PF03315 Serine dehydratase beta chain 3 153 8.8E-53 T 05-07-2017 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 K08M4_RS16970 bac5af1961b90ed34af70286cb903773 456 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 448 3.8E-198 T 05-07-2017 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 K08M4_RS16970 bac5af1961b90ed34af70286cb903773 456 Gene3D G3DSA:3.30.1330.90 10 155 4.2E-51 T 05-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 K08M4_RS16425 03e2fc6dbfe6a802ec816dd88ae0b31d 430 Gene3D G3DSA:2.70.70.10 249 391 4.6E-44 T 05-07-2017 K08M4_RS16425 03e2fc6dbfe6a802ec816dd88ae0b31d 430 Pfam PF04225 Opacity-associated protein A LysM-like domain 73 154 5.8E-5 T 05-07-2017 IPR007340 Opacity-associated protein A K08M4_RS16425 03e2fc6dbfe6a802ec816dd88ae0b31d 430 SUPERFAMILY SSF51261 144 390 1.67E-65 T 05-07-2017 IPR011055 Duplicated hybrid motif K08M4_RS16425 03e2fc6dbfe6a802ec816dd88ae0b31d 430 Pfam PF01551 Peptidase family M23 295 388 4.0E-31 T 05-07-2017 IPR016047 Peptidase M23 K08M4_RS15385 8b69da027894ff647c6b00e9062e87ed 263 Pfam PF12833 Helix-turn-helix domain 183 259 4.9E-19 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS15385 8b69da027894ff647c6b00e9062e87ed 263 Gene3D G3DSA:1.10.10.60 215 258 3.6E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS15385 8b69da027894ff647c6b00e9062e87ed 263 Gene3D G3DSA:2.60.120.10 35 86 6.4E-9 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS15385 8b69da027894ff647c6b00e9062e87ed 263 Gene3D G3DSA:1.10.10.60 162 214 2.0E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS15385 8b69da027894ff647c6b00e9062e87ed 263 SUPERFAMILY SSF51182 35 88 1.08E-7 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS15385 8b69da027894ff647c6b00e9062e87ed 263 SMART SM00342 177 259 3.4E-19 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS15385 8b69da027894ff647c6b00e9062e87ed 263 Pfam PF02311 AraC-like ligand binding domain 24 100 1.9E-5 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 K08M4_RS15385 8b69da027894ff647c6b00e9062e87ed 263 SUPERFAMILY SSF46689 179 212 6.27E-5 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS15385 8b69da027894ff647c6b00e9062e87ed 263 SUPERFAMILY SSF46689 213 260 8.24E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS19740 cf1374d754161f8b24f4101eb4740daf 353 Gene3D G3DSA:3.30.70.270 191 343 1.6E-46 T 05-07-2017 K08M4_RS19740 cf1374d754161f8b24f4101eb4740daf 353 SUPERFAMILY SSF55073 194 341 8.63E-43 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS19740 cf1374d754161f8b24f4101eb4740daf 353 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 189 340 7.9E-45 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS19740 cf1374d754161f8b24f4101eb4740daf 353 SUPERFAMILY SSF55785 77 186 2.62E-11 T 05-07-2017 IPR000014 PAS domain K08M4_RS19740 cf1374d754161f8b24f4101eb4740daf 353 SMART SM00267 178 342 2.4E-49 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS19740 cf1374d754161f8b24f4101eb4740daf 353 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 69 185 2.3E-10 T 05-07-2017 IPR000014 PAS domain K08M4_RS19740 cf1374d754161f8b24f4101eb4740daf 353 Pfam PF00990 Diguanylate cyclase, GGDEF domain 191 338 3.4E-39 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS19740 cf1374d754161f8b24f4101eb4740daf 353 Pfam PF13426 PAS domain 76 176 9.4E-9 T 05-07-2017 IPR000014 PAS domain K08M4_RS19740 cf1374d754161f8b24f4101eb4740daf 353 Gene3D G3DSA:3.30.450.20 61 176 1.2E-9 T 05-07-2017 K08M4_RS01590 6e24cbce3ab074aae0b3f34e110bf8c3 330 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 29 229 2.5E-23 T 05-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS01590 6e24cbce3ab074aae0b3f34e110bf8c3 330 SUPERFAMILY SSF55257 7 53 5.69E-30 T 05-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS01590 6e24cbce3ab074aae0b3f34e110bf8c3 330 SUPERFAMILY SSF55257 180 234 5.69E-30 T 05-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS01590 6e24cbce3ab074aae0b3f34e110bf8c3 330 Gene3D G3DSA:1.10.150.20 245 329 7.2E-38 T 05-07-2017 K08M4_RS01590 6e24cbce3ab074aae0b3f34e110bf8c3 330 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 246 309 5.6E-24 T 05-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS01590 6e24cbce3ab074aae0b3f34e110bf8c3 330 Gene3D G3DSA:3.30.1360.10 9 57 2.7E-10 T 05-07-2017 K08M4_RS01590 6e24cbce3ab074aae0b3f34e110bf8c3 330 SUPERFAMILY SSF56553 53 179 1.73E-40 T 05-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS01590 6e24cbce3ab074aae0b3f34e110bf8c3 330 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 24 317 1.2E-111 T 05-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS01590 6e24cbce3ab074aae0b3f34e110bf8c3 330 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 257 330 2.0E-36 T 05-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS01590 6e24cbce3ab074aae0b3f34e110bf8c3 330 Gene3D G3DSA:2.170.120.12 58 178 9.2E-41 T 05-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS01590 6e24cbce3ab074aae0b3f34e110bf8c3 330 SUPERFAMILY SSF47789 252 326 1.44E-25 T 05-07-2017 K08M4_RS01590 6e24cbce3ab074aae0b3f34e110bf8c3 330 SMART SM00662 23 235 1.0E-103 T 05-07-2017 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS01590 6e24cbce3ab074aae0b3f34e110bf8c3 330 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 5 318 34.691 T 05-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS01590 6e24cbce3ab074aae0b3f34e110bf8c3 330 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 62 157 4.2E-24 T 05-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS12950 f56452c99b12cd7ca78ad3fe699880e3 284 Gene3D G3DSA:1.10.3680.10 20 222 1.9E-40 T 05-07-2017 IPR029024 TerB-like K08M4_RS12950 f56452c99b12cd7ca78ad3fe699880e3 284 Gene3D G3DSA:1.10.287.110 223 278 8.9E-17 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS12950 f56452c99b12cd7ca78ad3fe699880e3 284 PRINTS PR00625 DnaJ domain signature 220 238 2.4E-11 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS12950 f56452c99b12cd7ca78ad3fe699880e3 284 PRINTS PR00625 DnaJ domain signature 238 253 2.4E-11 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS12950 f56452c99b12cd7ca78ad3fe699880e3 284 PRINTS PR00625 DnaJ domain signature 262 282 2.4E-11 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS12950 f56452c99b12cd7ca78ad3fe699880e3 284 Pfam PF05099 Tellurite resistance protein TerB 46 177 1.4E-16 T 05-07-2017 IPR007791 Co-chaperone DjlA, N-terminal K08M4_RS12950 f56452c99b12cd7ca78ad3fe699880e3 284 SUPERFAMILY SSF158682 48 181 4.18E-23 T 05-07-2017 IPR029024 TerB-like K08M4_RS12950 f56452c99b12cd7ca78ad3fe699880e3 284 SMART SM00271 217 282 1.9E-18 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS12950 f56452c99b12cd7ca78ad3fe699880e3 284 Hamap MF_01153 Co-chaperone protein DjlA [djlA]. 3 283 39.612 T 05-07-2017 IPR023749 Co-chaperone DjlA GO:0051087 K08M4_RS12950 f56452c99b12cd7ca78ad3fe699880e3 284 SUPERFAMILY SSF46565 138 279 5.55E-33 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS12950 f56452c99b12cd7ca78ad3fe699880e3 284 Pfam PF00226 DnaJ domain 218 278 2.5E-13 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 Pfam PF00958 GMP synthase C terminal domain 425 516 1.4E-43 T 05-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 51 65 5.0E-7 T 05-07-2017 K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 5.0E-7 T 05-07-2017 K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 10 24 5.0E-7 T 05-07-2017 K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 10 197 9.2E-85 T 05-07-2017 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 Gene3D G3DSA:3.40.50.620 216 391 6.7E-58 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 Gene3D G3DSA:3.40.50.880 4 215 4.1E-65 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 Pfam PF02540 NAD synthase 212 285 2.7E-8 T 05-07-2017 IPR022310 NAD/GMP synthase K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 PRINTS PR00097 Anthranilate synthase component II signature 81 92 4.3E-6 T 05-07-2017 K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 PRINTS PR00097 Anthranilate synthase component II signature 54 63 4.3E-6 T 05-07-2017 K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 PRINTS PR00097 Anthranilate synthase component II signature 169 182 4.3E-6 T 05-07-2017 K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 205 517 5.3E-156 T 05-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 SUPERFAMILY SSF52402 189 412 9.48E-59 T 05-07-2017 K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 Pfam PF00117 Glutamine amidotransferase class-I 12 192 1.1E-43 T 05-07-2017 IPR017926 Glutamine amidotransferase K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 7 517 56.44 T 05-07-2017 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 SUPERFAMILY SSF52317 8 229 2.29E-59 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 Gene3D G3DSA:3.30.300.10 393 517 2.1E-53 T 05-07-2017 K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 1.2E-7 T 05-07-2017 K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 1.2E-7 T 05-07-2017 K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 1.2E-7 T 05-07-2017 K08M4_RS11795 e7f28fa30f12bd89ae5aa3d7b0ba0fb2 517 SUPERFAMILY SSF54810 397 517 4.97E-51 T 05-07-2017 K08M4_RS02885 870732f4fa60a3edd624b53cd5342529 451 Pfam PF12626 Polymerase A arginine-rich C-terminus 325 444 3.0E-38 T 05-07-2017 IPR025866 Polymerase A arginine-rich C-terminal domain K08M4_RS02885 870732f4fa60a3edd624b53cd5342529 451 Gene3D G3DSA:1.10.3090.10 181 416 5.7E-52 T 05-07-2017 K08M4_RS02885 870732f4fa60a3edd624b53cd5342529 451 Pfam PF01743 Poly A polymerase head domain 52 181 1.5E-37 T 05-07-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 K08M4_RS02885 870732f4fa60a3edd624b53cd5342529 451 SUPERFAMILY SSF81301 23 178 3.92E-40 T 05-07-2017 K08M4_RS02885 870732f4fa60a3edd624b53cd5342529 451 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 7 450 37.478 T 05-07-2017 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 K08M4_RS02885 870732f4fa60a3edd624b53cd5342529 451 SUPERFAMILY SSF81891 179 391 9.94E-49 T 05-07-2017 K08M4_RS02885 870732f4fa60a3edd624b53cd5342529 451 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 21 448 4.7E-163 T 05-07-2017 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 K08M4_RS02885 870732f4fa60a3edd624b53cd5342529 451 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 208 269 5.1E-22 T 05-07-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 K08M4_RS02885 870732f4fa60a3edd624b53cd5342529 451 Gene3D G3DSA:3.30.460.10 33 180 1.4E-49 T 05-07-2017 K08M4_RS03160 1f3e03f19feeaa322ceedcfce9e71435 445 Pfam PF01554 MatE 239 399 1.6E-13 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS03160 1f3e03f19feeaa322ceedcfce9e71435 445 Pfam PF01554 MatE 15 176 3.0E-22 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS03160 1f3e03f19feeaa322ceedcfce9e71435 445 PIRSF PIRSF006603 1 442 1.9E-67 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS03160 1f3e03f19feeaa322ceedcfce9e71435 445 TIGRFAM TIGR00797 matE: MATE efflux family protein 15 409 3.7E-48 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS00035 8b137523481c3aadd727b4099f46affa 693 Pfam PF05746 DALR anticodon binding domain 585 682 3.5E-10 T 05-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 K08M4_RS00035 8b137523481c3aadd727b4099f46affa 693 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 691 25.947 T 05-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS00035 8b137523481c3aadd727b4099f46affa 693 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 3 691 2.9E-289 T 05-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS00035 8b137523481c3aadd727b4099f46affa 693 SUPERFAMILY SSF109604 357 493 9.1E-12 T 05-07-2017 K08M4_RS00035 8b137523481c3aadd727b4099f46affa 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 245 260 7.9E-36 T 05-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS00035 8b137523481c3aadd727b4099f46affa 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 398 417 7.9E-36 T 05-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS00035 8b137523481c3aadd727b4099f46affa 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 49 61 7.9E-36 T 05-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS00035 8b137523481c3aadd727b4099f46affa 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 7.9E-36 T 05-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS00035 8b137523481c3aadd727b4099f46affa 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 322 338 7.9E-36 T 05-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS00035 8b137523481c3aadd727b4099f46affa 693 Gene3D G3DSA:1.10.730.10 587 681 9.1E-7 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS00035 8b137523481c3aadd727b4099f46affa 693 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 554 3.4E-203 T 05-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS16590 186e34977549f204e02a0c7359395fd5 219 SUPERFAMILY SSF50475 2 184 6.29E-52 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 K08M4_RS16590 186e34977549f204e02a0c7359395fd5 219 Gene3D G3DSA:2.30.110.10 2 184 2.7E-62 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 K08M4_RS16590 186e34977549f204e02a0c7359395fd5 219 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 21 162 3.1E-39 T 05-07-2017 IPR024747 Pyridoxamine 5'-phosphate oxidase-related K08M4_RS13080 ed06c0d397a79299e513e80acf60a3f7 270 Gene3D G3DSA:3.60.110.10 4 266 4.5E-79 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 K08M4_RS13080 ed06c0d397a79299e513e80acf60a3f7 270 SUPERFAMILY SSF56317 4 263 1.96E-73 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 K08M4_RS13080 ed06c0d397a79299e513e80acf60a3f7 270 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 149 169 - T 05-07-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site K08M4_RS13080 ed06c0d397a79299e513e80acf60a3f7 270 Pfam PF00795 Carbon-nitrogen hydrolase 24 256 6.5E-46 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 K08M4_RS00550 896e282c2dfae6bc366f761643bced22 200 SUPERFAMILY SSF53335 19 194 1.28E-53 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS00550 896e282c2dfae6bc366f761643bced22 200 Pfam PF03602 Conserved hypothetical protein 95 19 194 1.1E-61 T 05-07-2017 K08M4_RS00550 896e282c2dfae6bc366f761643bced22 200 Gene3D G3DSA:3.40.50.150 11 196 6.9E-68 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS00550 896e282c2dfae6bc366f761643bced22 200 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 18 196 8.4E-63 T 05-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS00550 896e282c2dfae6bc366f761643bced22 200 PIRSF PIRSF004553 18 198 6.1E-55 T 05-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS00550 896e282c2dfae6bc366f761643bced22 200 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 131 137 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 K08M4_RS11195 952dd333c6d4a3e2bb3f8b28b8173e36 402 SUPERFAMILY SSF55347 126 274 7.19E-63 T 05-07-2017 K08M4_RS11195 952dd333c6d4a3e2bb3f8b28b8173e36 402 Gene3D G3DSA:3.40.50.720 1 150 7.4E-54 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS11195 952dd333c6d4a3e2bb3f8b28b8173e36 402 Pfam PF13288 DXP reductoisomerase C-terminal domain 271 391 7.8E-38 T 05-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 K08M4_RS11195 952dd333c6d4a3e2bb3f8b28b8173e36 402 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 146 239 3.8E-37 T 05-07-2017 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 K08M4_RS11195 952dd333c6d4a3e2bb3f8b28b8173e36 402 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 396 45.702 T 05-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 K08M4_RS11195 952dd333c6d4a3e2bb3f8b28b8173e36 402 PIRSF PIRSF006205 1 402 2.1E-153 T 05-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 K08M4_RS11195 952dd333c6d4a3e2bb3f8b28b8173e36 402 SUPERFAMILY SSF69055 301 399 2.62E-29 T 05-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 K08M4_RS11195 952dd333c6d4a3e2bb3f8b28b8173e36 402 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 132 8.1E-46 T 05-07-2017 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 K08M4_RS11195 952dd333c6d4a3e2bb3f8b28b8173e36 402 SUPERFAMILY SSF51735 2 150 1.03E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS11195 952dd333c6d4a3e2bb3f8b28b8173e36 402 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 397 1.5E-163 T 05-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 K08M4_RS11195 952dd333c6d4a3e2bb3f8b28b8173e36 402 Gene3D G3DSA:1.10.1740.10 313 399 7.3E-27 T 05-07-2017 K08M4_RS12175 bbaca2d9ca43de1dca080c864c3651c7 336 Gene3D G3DSA:2.70.70.10 151 275 2.4E-43 T 05-07-2017 K08M4_RS12175 bbaca2d9ca43de1dca080c864c3651c7 336 SUPERFAMILY SSF51261 103 273 8.24E-50 T 05-07-2017 IPR011055 Duplicated hybrid motif K08M4_RS12175 bbaca2d9ca43de1dca080c864c3651c7 336 Pfam PF01551 Peptidase family M23 176 271 5.4E-29 T 05-07-2017 IPR016047 Peptidase M23 K08M4_RS09460 bfe54e1bb29eae786c147a652ae78344 170 SUPERFAMILY SSF103642 150 170 4.41E-8 T 05-07-2017 K08M4_RS09460 bfe54e1bb29eae786c147a652ae78344 170 Gene3D G3DSA:3.10.450.50 2 170 1.2E-55 T 05-07-2017 IPR032710 NTF2-like domain K08M4_RS09460 bfe54e1bb29eae786c147a652ae78344 170 SUPERFAMILY SSF54427 27 127 1.93E-34 T 05-07-2017 IPR032710 NTF2-like domain K08M4_RS09460 bfe54e1bb29eae786c147a652ae78344 170 Pfam PF02810 SEC-C motif 153 170 3.5E-10 T 05-07-2017 IPR004027 SEC-C motif K08M4_RS09460 bfe54e1bb29eae786c147a652ae78344 170 Pfam PF02810 SEC-C motif 3 17 3.0E-4 T 05-07-2017 IPR004027 SEC-C motif K08M4_RS18945 dc08244b3b37299181b705637770b1a8 136 Pfam PF00472 RF-1 domain 6 132 4.3E-27 T 05-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 K08M4_RS18945 dc08244b3b37299181b705637770b1a8 136 SUPERFAMILY SSF75620 7 124 4.32E-13 T 05-07-2017 K08M4_RS18945 dc08244b3b37299181b705637770b1a8 136 Gene3D G3DSA:3.30.160.200 2 107 3.7E-34 T 05-07-2017 K08M4_RS18945 dc08244b3b37299181b705637770b1a8 136 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 05-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 K08M4_RS14135 ca1474149de727a4b59c9922f3aefbb0 708 SUPERFAMILY SSF109604 3 190 4.39E-74 T 05-07-2017 K08M4_RS14135 ca1474149de727a4b59c9922f3aefbb0 708 Pfam PF04607 Region found in RelA / SpoT proteins 235 344 2.9E-33 T 05-07-2017 IPR007685 RelA/SpoT GO:0015969 K08M4_RS14135 ca1474149de727a4b59c9922f3aefbb0 708 Gene3D G3DSA:3.10.20.30 390 450 2.6E-19 T 05-07-2017 IPR012675 Beta-grasp domain K08M4_RS14135 ca1474149de727a4b59c9922f3aefbb0 708 Gene3D G3DSA:3.30.460.10 178 324 1.4E-45 T 05-07-2017 K08M4_RS14135 ca1474149de727a4b59c9922f3aefbb0 708 SMART SM00954 235 345 1.4E-57 T 05-07-2017 IPR007685 RelA/SpoT GO:0015969 K08M4_RS14135 ca1474149de727a4b59c9922f3aefbb0 708 SUPERFAMILY SSF55021 630 705 3.82E-9 T 05-07-2017 K08M4_RS14135 ca1474149de727a4b59c9922f3aefbb0 708 Pfam PF13328 HD domain 28 175 7.5E-53 T 05-07-2017 IPR003607 HD/PDEase domain K08M4_RS14135 ca1474149de727a4b59c9922f3aefbb0 708 Pfam PF02824 TGS domain 391 449 4.7E-18 T 05-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 K08M4_RS14135 ca1474149de727a4b59c9922f3aefbb0 708 Gene3D G3DSA:3.30.70.260 631 696 1.0E-10 T 05-07-2017 K08M4_RS14135 ca1474149de727a4b59c9922f3aefbb0 708 SMART SM00471 41 153 4.2E-10 T 05-07-2017 IPR003607 HD/PDEase domain K08M4_RS14135 ca1474149de727a4b59c9922f3aefbb0 708 Pfam PF13291 ACT domain 628 705 5.7E-17 T 05-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 K08M4_RS14135 ca1474149de727a4b59c9922f3aefbb0 708 SUPERFAMILY SSF81271 378 450 1.94E-19 T 05-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 K08M4_RS14135 ca1474149de727a4b59c9922f3aefbb0 708 SUPERFAMILY SSF81301 180 395 1.8E-58 T 05-07-2017 K08M4_RS14135 ca1474149de727a4b59c9922f3aefbb0 708 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 27 705 1.0E-267 T 05-07-2017 IPR004811 RelA/SpoT family GO:0015969 K08M4_RS18370 8fbd0fce4a98c64319ff78fc41ffbb61 144 SUPERFAMILY SSF52833 29 142 3.57E-36 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS18370 8fbd0fce4a98c64319ff78fc41ffbb61 144 Gene3D G3DSA:3.40.30.10 37 142 1.7E-35 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS18370 8fbd0fce4a98c64319ff78fc41ffbb61 144 Pfam PF00085 Thioredoxin 44 140 9.2E-28 T 05-07-2017 IPR013766 Thioredoxin domain GO:0045454 K08M4_RS18370 8fbd0fce4a98c64319ff78fc41ffbb61 144 PRINTS PR00421 Thioredoxin family signature 58 66 6.6E-7 T 05-07-2017 K08M4_RS18370 8fbd0fce4a98c64319ff78fc41ffbb61 144 PRINTS PR00421 Thioredoxin family signature 106 117 6.6E-7 T 05-07-2017 K08M4_RS18370 8fbd0fce4a98c64319ff78fc41ffbb61 144 PRINTS PR00421 Thioredoxin family signature 66 75 6.6E-7 T 05-07-2017 K08M4_RS18370 8fbd0fce4a98c64319ff78fc41ffbb61 144 TIGRFAM TIGR01068 thioredoxin: thioredoxin 47 141 5.9E-35 T 05-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 K08M4_RS07665 b133b318313ef10917c664b9f23e99c5 477 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 17 447 9.3E-115 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS07665 b133b318313ef10917c664b9f23e99c5 477 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 207 262 - T 05-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS07665 b133b318313ef10917c664b9f23e99c5 477 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 11 468 3.0E-229 T 05-07-2017 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 K08M4_RS07665 b133b318313ef10917c664b9f23e99c5 477 SUPERFAMILY SSF81442 13 467 3.14E-122 T 05-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS07665 b133b318313ef10917c664b9f23e99c5 477 Gene3D G3DSA:1.20.210.10 9 468 3.0E-70 T 05-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS10755 ea4752528b980ebce0b897d7222bc6c0 166 SMART SM00244 22 166 3.1E-45 T 05-07-2017 IPR001107 Band 7 domain K08M4_RS10755 ea4752528b980ebce0b897d7222bc6c0 166 PRINTS PR00721 Stomatin signature 77 98 6.8E-20 T 05-07-2017 IPR001972 Stomatin family GO:0016020 K08M4_RS10755 ea4752528b980ebce0b897d7222bc6c0 166 PRINTS PR00721 Stomatin signature 156 166 6.8E-20 T 05-07-2017 IPR001972 Stomatin family GO:0016020 K08M4_RS10755 ea4752528b980ebce0b897d7222bc6c0 166 PRINTS PR00721 Stomatin signature 112 129 6.8E-20 T 05-07-2017 IPR001972 Stomatin family GO:0016020 K08M4_RS10755 ea4752528b980ebce0b897d7222bc6c0 166 PRINTS PR00721 Stomatin signature 132 155 6.8E-20 T 05-07-2017 IPR001972 Stomatin family GO:0016020 K08M4_RS10755 ea4752528b980ebce0b897d7222bc6c0 166 PRINTS PR00721 Stomatin signature 29 51 6.8E-20 T 05-07-2017 IPR001972 Stomatin family GO:0016020 K08M4_RS10755 ea4752528b980ebce0b897d7222bc6c0 166 SUPERFAMILY SSF117892 53 162 1.44E-32 T 05-07-2017 IPR001107 Band 7 domain K08M4_RS10755 ea4752528b980ebce0b897d7222bc6c0 166 Pfam PF01145 SPFH domain / Band 7 family 26 161 1.3E-26 T 05-07-2017 IPR001107 Band 7 domain K08M4_RS05375 dcb4525c3e58b45274dc0b85d99859d5 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 1.5E-27 T 05-07-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 K08M4_RS05375 dcb4525c3e58b45274dc0b85d99859d5 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.238 T 05-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 K08M4_RS05375 dcb4525c3e58b45274dc0b85d99859d5 72 SUPERFAMILY SSF50249 1 70 9.43E-29 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS05375 dcb4525c3e58b45274dc0b85d99859d5 72 SMART SM00316 4 72 4.8E-6 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS05375 dcb4525c3e58b45274dc0b85d99859d5 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 1.5E-38 T 05-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 K08M4_RS05375 dcb4525c3e58b45274dc0b85d99859d5 72 Gene3D G3DSA:2.40.50.140 1 71 3.9E-39 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS02775 d11554dcbfabbb179d33a105c194991f 246 Hamap MF_01092 Cell division protein ZapD [zapD]. 3 245 32.504 T 05-07-2017 IPR009777 Cell division protein ZapD K08M4_RS02775 d11554dcbfabbb179d33a105c194991f 246 SUPERFAMILY SSF160950 3 245 9.29E-94 T 05-07-2017 K08M4_RS02775 d11554dcbfabbb179d33a105c194991f 246 Pfam PF07072 Protein of unknown function (DUF1342) 18 224 3.7E-75 T 05-07-2017 IPR009777 Cell division protein ZapD K08M4_RS02775 d11554dcbfabbb179d33a105c194991f 246 Gene3D G3DSA:1.10.3900.10 12 172 5.4E-63 T 05-07-2017 K08M4_RS02775 d11554dcbfabbb179d33a105c194991f 246 Gene3D G3DSA:2.60.440.10 173 245 9.6E-34 T 05-07-2017 IPR027462 Z ring-associated protein D, C-terminal domain K08M4_RS02780 77b813746c5b8e1cceef248dcb1c11c3 204 Pfam PF01121 Dephospho-CoA kinase 3 181 1.1E-70 T 05-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 K08M4_RS02780 77b813746c5b8e1cceef248dcb1c11c3 204 Gene3D G3DSA:3.40.50.300 2 196 8.9E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02780 77b813746c5b8e1cceef248dcb1c11c3 204 PRINTS PR00988 Uridine kinase signature 2 19 2.2E-7 T 05-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 K08M4_RS02780 77b813746c5b8e1cceef248dcb1c11c3 204 PRINTS PR00988 Uridine kinase signature 136 146 2.2E-7 T 05-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 K08M4_RS02780 77b813746c5b8e1cceef248dcb1c11c3 204 SUPERFAMILY SSF52540 1 193 1.45E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02780 77b813746c5b8e1cceef248dcb1c11c3 204 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 188 2.4E-62 T 05-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 K08M4_RS02780 77b813746c5b8e1cceef248dcb1c11c3 204 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 197 27.488 T 05-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 K08M4_RS02380 7fb323cba166afb859a3e51caaceb91e 191 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 16 176 2.8E-9 T 05-07-2017 IPR011978 Uncharacterised protein family UPF0149 K08M4_RS02380 7fb323cba166afb859a3e51caaceb91e 191 SUPERFAMILY SSF101327 7 178 5.89E-43 T 05-07-2017 IPR011978 Uncharacterised protein family UPF0149 K08M4_RS02380 7fb323cba166afb859a3e51caaceb91e 191 Hamap MF_00346 UPF0149 protein YgfB [ygfB]. 5 189 32.151 T 05-07-2017 IPR011978 Uncharacterised protein family UPF0149 K08M4_RS02380 7fb323cba166afb859a3e51caaceb91e 191 Pfam PF03695 Uncharacterised protein family (UPF0149) 13 179 2.3E-34 T 05-07-2017 IPR011978 Uncharacterised protein family UPF0149 K08M4_RS19570 34f5b46917d4c99ce6255f865b518441 114 Pfam PF01844 HNH endonuclease 31 79 6.1E-11 T 05-07-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 K08M4_RS19570 34f5b46917d4c99ce6255f865b518441 114 SMART SM00507 19 74 2.9E-4 T 05-07-2017 IPR003615 HNH nuclease K08M4_RS12700 2001eaf49366e869277e6f98ee277fc1 752 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 10 744 0.0 T 05-07-2017 K08M4_RS12700 2001eaf49366e869277e6f98ee277fc1 752 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 6 745 33.763 T 05-07-2017 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12700 2001eaf49366e869277e6f98ee277fc1 752 Gene3D G3DSA:3.30.1360.40 240 333 1.6E-25 T 05-07-2017 IPR024946 Arginine repressor C-terminal-like domain K08M4_RS12700 2001eaf49366e869277e6f98ee277fc1 752 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 34 470 1.3E-135 T 05-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12700 2001eaf49366e869277e6f98ee277fc1 752 SUPERFAMILY SSF56719 33 485 1.83E-155 T 05-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 K08M4_RS12700 2001eaf49366e869277e6f98ee277fc1 752 SMART SM00434 13 463 2.4E-226 T 05-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12700 2001eaf49366e869277e6f98ee277fc1 752 Gene3D G3DSA:2.120.10.90 498 731 8.7E-27 T 05-07-2017 K08M4_RS12700 2001eaf49366e869277e6f98ee277fc1 752 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 600 630 0.71 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12700 2001eaf49366e869277e6f98ee277fc1 752 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 648 697 8.9E-8 T 05-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12700 2001eaf49366e869277e6f98ee277fc1 752 Gene3D G3DSA:3.90.199.10 32 239 7.6E-106 T 05-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12700 2001eaf49366e869277e6f98ee277fc1 752 Gene3D G3DSA:3.90.199.10 335 399 7.6E-106 T 05-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12700 2001eaf49366e869277e6f98ee277fc1 752 SUPERFAMILY SSF101904 499 743 4.05E-51 T 05-07-2017 K08M4_RS12495 6026df328f94aa7ea6a76bd5acb8e7f4 289 Gene3D G3DSA:3.40.50.1980 37 154 8.7E-27 T 05-07-2017 K08M4_RS12495 6026df328f94aa7ea6a76bd5acb8e7f4 289 Gene3D G3DSA:3.40.50.1980 158 282 2.3E-35 T 05-07-2017 K08M4_RS12495 6026df328f94aa7ea6a76bd5acb8e7f4 289 Hamap MF_01000 Vitamin B12-binding protein [btuF]. 10 286 47.801 T 05-07-2017 IPR023544 ABC transporter, vitamin B12-binding protein GO:0015889|GO:0031419|GO:0042597 K08M4_RS12495 6026df328f94aa7ea6a76bd5acb8e7f4 289 SUPERFAMILY SSF53807 36 282 9.81E-54 T 05-07-2017 K08M4_RS12495 6026df328f94aa7ea6a76bd5acb8e7f4 289 Pfam PF01497 Periplasmic binding protein 40 261 6.6E-24 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 K08M4_RS11900 19230f4441bedc47230075afc2969457 404 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 1 395 53.401 T 05-07-2017 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 K08M4_RS11900 19230f4441bedc47230075afc2969457 404 Gene3D G3DSA:3.40.640.10 17 253 5.3E-97 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS11900 19230f4441bedc47230075afc2969457 404 Gene3D G3DSA:3.90.1150.10 254 374 5.2E-51 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS11900 19230f4441bedc47230075afc2969457 404 Pfam PF00266 Aminotransferase class-V 5 368 3.0E-87 T 05-07-2017 IPR000192 Aminotransferase class V domain K08M4_RS11900 19230f4441bedc47230075afc2969457 404 PIRSF PIRSF005572 2 384 5.2E-135 T 05-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 K08M4_RS11900 19230f4441bedc47230075afc2969457 404 SUPERFAMILY SSF53383 5 391 1.06E-113 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS11900 19230f4441bedc47230075afc2969457 404 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 197 216 - T 05-07-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site K08M4_RS11900 19230f4441bedc47230075afc2969457 404 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 1 404 3.4E-226 T 05-07-2017 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 25 621 2.2E-255 T 05-07-2017 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 Pfam PF00175 Oxidoreductase NAD-binding domain 479 585 1.3E-20 T 05-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 503 512 6.0E-30 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 441 450 6.0E-30 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 292 302 6.0E-30 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 547 563 6.0E-30 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 516 527 6.0E-30 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 408 415 6.0E-30 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 478 497 6.0E-30 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 570 578 6.0E-30 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 Gene3D G3DSA:3.40.50.80 477 621 3.3E-62 T 05-07-2017 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 Gene3D G3DSA:1.20.990.10 303 405 1.5E-32 T 05-07-2017 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 GO:0016491|GO:0055114 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 Pfam PF00258 Flavodoxin 87 217 8.3E-30 T 05-07-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 Pfam PF00667 FAD binding domain 254 442 3.7E-27 T 05-07-2017 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 PRINTS PR00369 Flavodoxin signature 134 145 1.3E-10 T 05-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 PRINTS PR00369 Flavodoxin signature 86 99 1.3E-10 T 05-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 PRINTS PR00369 Flavodoxin signature 166 176 1.3E-10 T 05-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 PRINTS PR00369 Flavodoxin signature 190 209 1.3E-10 T 05-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 SUPERFAMILY SSF52343 466 621 2.75E-52 T 05-07-2017 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 SUPERFAMILY SSF52218 84 231 4.37E-47 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 Gene3D G3DSA:2.40.30.10 406 476 9.5E-40 T 05-07-2017 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 Gene3D G3DSA:2.40.30.10 250 302 9.5E-40 T 05-07-2017 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 Hamap MF_01541 Sulfite reductase [NADPH] flavoprotein alpha-component [cysJ]. 17 621 48.938 T 05-07-2017 IPR029758 Sulphite reductase [NADPH] flavoprotein, alpha chain, Proteobacteria GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 PIRSF PIRSF000207 17 621 6.4E-271 T 05-07-2017 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 Gene3D G3DSA:3.40.50.360 78 231 1.7E-47 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS13370 0ed22c2749a3efef6dc37a3ef9b69355 621 SUPERFAMILY SSF63380 251 467 5.1E-61 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 K08M4_RS09475 6ee8ffebbd76cd5c156c1b0da6a28837 245 Pfam PF00977 Histidine biosynthesis protein 1 234 5.7E-75 T 05-07-2017 IPR006062 Histidine biosynthesis GO:0000105 K08M4_RS09475 6ee8ffebbd76cd5c156c1b0da6a28837 245 Gene3D G3DSA:3.20.20.70 1 242 5.9E-76 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS09475 6ee8ffebbd76cd5c156c1b0da6a28837 245 SUPERFAMILY SSF51366 1 242 6.39E-64 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 K08M4_RS09475 6ee8ffebbd76cd5c156c1b0da6a28837 245 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 1 241 34.613 T 05-07-2017 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 K08M4_RS09475 6ee8ffebbd76cd5c156c1b0da6a28837 245 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 2 238 2.8E-77 T 05-07-2017 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 K08M4_RS12850 3ef4c486ddb0de77bbdfab217cee1f21 610 Gene3D G3DSA:3.40.50.10490 447 610 2.3E-66 T 05-07-2017 K08M4_RS12850 3ef4c486ddb0de77bbdfab217cee1f21 610 Pfam PF01380 SIS domain 290 418 3.6E-32 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 K08M4_RS12850 3ef4c486ddb0de77bbdfab217cee1f21 610 Pfam PF01380 SIS domain 463 592 1.8E-24 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 K08M4_RS12850 3ef4c486ddb0de77bbdfab217cee1f21 610 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 610 40.418 T 05-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 K08M4_RS12850 3ef4c486ddb0de77bbdfab217cee1f21 610 Pfam PF13522 Glutamine amidotransferase domain 54 174 7.0E-22 T 05-07-2017 K08M4_RS12850 3ef4c486ddb0de77bbdfab217cee1f21 610 SUPERFAMILY SSF56235 2 234 8.06E-76 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS12850 3ef4c486ddb0de77bbdfab217cee1f21 610 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 610 1.0E-259 T 05-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 K08M4_RS12850 3ef4c486ddb0de77bbdfab217cee1f21 610 SUPERFAMILY SSF53697 245 610 3.25E-114 T 05-07-2017 K08M4_RS12850 3ef4c486ddb0de77bbdfab217cee1f21 610 Gene3D G3DSA:3.40.50.10490 245 446 1.0E-66 T 05-07-2017 K08M4_RS12850 3ef4c486ddb0de77bbdfab217cee1f21 610 Gene3D G3DSA:3.60.20.10 2 237 5.1E-79 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS11805 9fbd6d22308025b0823130cbbb403306 448 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 4 440 30.364 T 05-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 K08M4_RS11805 9fbd6d22308025b0823130cbbb403306 448 Pfam PF13742 OB-fold nucleic acid binding domain 7 100 2.0E-30 T 05-07-2017 IPR025824 OB-fold nucleic acid binding domain GO:0003676 K08M4_RS11805 9fbd6d22308025b0823130cbbb403306 448 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 8 353 8.6E-134 T 05-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 K08M4_RS11805 9fbd6d22308025b0823130cbbb403306 448 Pfam PF02601 Exonuclease VII, large subunit 123 437 3.9E-99 T 05-07-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 K08M4_RS06720 e5f2978fc06e9dc3c9df58e0a93f4f9f 413 Pfam PF13356 Domain of unknown function (DUF4102) 8 93 5.0E-19 T 05-07-2017 IPR025166 Domain of unknown function DUF4102 K08M4_RS06720 e5f2978fc06e9dc3c9df58e0a93f4f9f 413 Pfam PF00589 Phage integrase family 214 376 7.5E-23 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS06720 e5f2978fc06e9dc3c9df58e0a93f4f9f 413 Gene3D G3DSA:1.10.443.10 214 384 2.9E-23 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS06720 e5f2978fc06e9dc3c9df58e0a93f4f9f 413 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 106 159 3.8E-10 T 05-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 K08M4_RS06720 e5f2978fc06e9dc3c9df58e0a93f4f9f 413 Gene3D G3DSA:1.10.150.130 105 201 7.2E-17 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal K08M4_RS06720 e5f2978fc06e9dc3c9df58e0a93f4f9f 413 SUPERFAMILY SSF56349 105 386 1.8E-57 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS18935 5f0c412084504dc1d90cbcf682a16a2f 634 SMART SM00086 418 460 8.1E-5 T 05-07-2017 IPR001610 PAC motif K08M4_RS18935 5f0c412084504dc1d90cbcf682a16a2f 634 Gene3D G3DSA:3.30.450.20 358 458 1.8E-19 T 05-07-2017 K08M4_RS18935 5f0c412084504dc1d90cbcf682a16a2f 634 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 357 467 3.6E-17 T 05-07-2017 IPR000014 PAS domain K08M4_RS18935 5f0c412084504dc1d90cbcf682a16a2f 634 Gene3D G3DSA:3.30.450.20 214 307 1.5E-20 T 05-07-2017 K08M4_RS18935 5f0c412084504dc1d90cbcf682a16a2f 634 Gene3D G3DSA:3.30.450.20 76 208 7.4E-40 T 05-07-2017 K08M4_RS18935 5f0c412084504dc1d90cbcf682a16a2f 634 Pfam PF13426 PAS domain 359 459 9.4E-12 T 05-07-2017 IPR000014 PAS domain K08M4_RS18935 5f0c412084504dc1d90cbcf682a16a2f 634 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 468 623 7.8E-37 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS18935 5f0c412084504dc1d90cbcf682a16a2f 634 Pfam PF00990 Diguanylate cyclase, GGDEF domain 473 620 1.1E-33 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS18935 5f0c412084504dc1d90cbcf682a16a2f 634 SMART SM00267 460 625 8.2E-45 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS18935 5f0c412084504dc1d90cbcf682a16a2f 634 Gene3D G3DSA:3.30.70.270 473 627 4.3E-41 T 05-07-2017 K08M4_RS18935 5f0c412084504dc1d90cbcf682a16a2f 634 SUPERFAMILY SSF103190 41 208 3.77E-45 T 05-07-2017 IPR029151 Periplasmic sensor domain-like K08M4_RS18935 5f0c412084504dc1d90cbcf682a16a2f 634 SUPERFAMILY SSF55785 358 457 2.44E-22 T 05-07-2017 IPR000014 PAS domain K08M4_RS18935 5f0c412084504dc1d90cbcf682a16a2f 634 SUPERFAMILY SSF55073 476 625 4.71E-38 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS18935 5f0c412084504dc1d90cbcf682a16a2f 634 Pfam PF02743 Cache domain 32 277 4.7E-13 T 05-07-2017 IPR033479 Double Cache domain 1 K08M4_RS18935 5f0c412084504dc1d90cbcf682a16a2f 634 SUPERFAMILY SSF103190 214 304 4.16E-18 T 05-07-2017 IPR029151 Periplasmic sensor domain-like K08M4_RS14790 51b2f48c0ee0e2bb6804f48ed710c554 195 Hamap MF_00163 Peptide deformylase [def]. 27 187 30.435 T 05-07-2017 IPR023635 Peptide deformylase K08M4_RS14790 51b2f48c0ee0e2bb6804f48ed710c554 195 Pfam PF01327 Polypeptide deformylase 29 177 1.3E-49 T 05-07-2017 IPR023635 Peptide deformylase K08M4_RS14790 51b2f48c0ee0e2bb6804f48ed710c554 195 PIRSF PIRSF004749 6 195 1.6E-55 T 05-07-2017 IPR023635 Peptide deformylase K08M4_RS14790 51b2f48c0ee0e2bb6804f48ed710c554 195 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 29 184 1.8E-59 T 05-07-2017 IPR023635 Peptide deformylase K08M4_RS14790 51b2f48c0ee0e2bb6804f48ed710c554 195 SUPERFAMILY SSF56420 28 190 1.96E-61 T 05-07-2017 IPR023635 Peptide deformylase K08M4_RS14790 51b2f48c0ee0e2bb6804f48ed710c554 195 PRINTS PR01576 Peptide deformylase signature 145 174 3.9E-37 T 05-07-2017 IPR023635 Peptide deformylase K08M4_RS14790 51b2f48c0ee0e2bb6804f48ed710c554 195 PRINTS PR01576 Peptide deformylase signature 58 87 3.9E-37 T 05-07-2017 IPR023635 Peptide deformylase K08M4_RS14790 51b2f48c0ee0e2bb6804f48ed710c554 195 PRINTS PR01576 Peptide deformylase signature 114 125 3.9E-37 T 05-07-2017 IPR023635 Peptide deformylase K08M4_RS14790 51b2f48c0ee0e2bb6804f48ed710c554 195 PRINTS PR01576 Peptide deformylase signature 126 144 3.9E-37 T 05-07-2017 IPR023635 Peptide deformylase K08M4_RS14790 51b2f48c0ee0e2bb6804f48ed710c554 195 Gene3D G3DSA:3.90.45.10 30 193 1.1E-62 T 05-07-2017 IPR023635 Peptide deformylase K08M4_RS11405 49d86fe42a7649b89e9d119ca2dc2bae 281 Gene3D G3DSA:3.30.1130.10 144 280 7.6E-56 T 05-07-2017 K08M4_RS11405 49d86fe42a7649b89e9d119ca2dc2bae 281 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 281 161.429 T 05-07-2017 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 K08M4_RS11405 49d86fe42a7649b89e9d119ca2dc2bae 281 Pfam PF14489 QueF-like protein 194 270 5.0E-27 T 05-07-2017 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 K08M4_RS11405 49d86fe42a7649b89e9d119ca2dc2bae 281 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 21 129 6.9E-49 T 05-07-2017 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 K08M4_RS11405 49d86fe42a7649b89e9d119ca2dc2bae 281 Gene3D G3DSA:3.30.1130.10 21 135 8.8E-46 T 05-07-2017 K08M4_RS11405 49d86fe42a7649b89e9d119ca2dc2bae 281 PIRSF PIRSF004750 6 281 8.3E-129 T 05-07-2017 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 K08M4_RS11405 49d86fe42a7649b89e9d119ca2dc2bae 281 SUPERFAMILY SSF55620 184 267 2.22E-9 T 05-07-2017 K08M4_RS11405 49d86fe42a7649b89e9d119ca2dc2bae 281 TIGRFAM TIGR03138 QueF: queuine synthase 11 281 1.2E-127 T 05-07-2017 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 K08M4_RS20860 d5e69a905eb2de9897c8da45a7fbbb23 450 Gene3D G3DSA:1.10.10.60 368 443 7.4E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20860 d5e69a905eb2de9897c8da45a7fbbb23 450 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 358 367 - T 05-07-2017 IPR025944 Sigma-54 interaction domain, conserved site K08M4_RS20860 d5e69a905eb2de9897c8da45a7fbbb23 450 Gene3D G3DSA:3.40.50.2300 5 128 1.1E-31 T 05-07-2017 K08M4_RS20860 d5e69a905eb2de9897c8da45a7fbbb23 450 SUPERFAMILY SSF52172 5 190 3.84E-36 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS20860 d5e69a905eb2de9897c8da45a7fbbb23 450 SMART SM00382 165 319 2.0E-6 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS20860 d5e69a905eb2de9897c8da45a7fbbb23 450 Gene3D G3DSA:1.10.8.60 318 367 6.3E-19 T 05-07-2017 K08M4_RS20860 d5e69a905eb2de9897c8da45a7fbbb23 450 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 231 246 - T 05-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 K08M4_RS20860 d5e69a905eb2de9897c8da45a7fbbb23 450 SMART SM00448 5 116 8.1E-30 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS20860 d5e69a905eb2de9897c8da45a7fbbb23 450 Gene3D G3DSA:3.40.50.300 145 317 3.6E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20860 d5e69a905eb2de9897c8da45a7fbbb23 450 Pfam PF02954 Bacterial regulatory protein, Fis family 401 441 2.8E-10 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS20860 d5e69a905eb2de9897c8da45a7fbbb23 450 Pfam PF00072 Response regulator receiver domain 7 116 3.8E-27 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS20860 d5e69a905eb2de9897c8da45a7fbbb23 450 Pfam PF00158 Sigma-54 interaction domain 145 311 2.4E-63 T 05-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 K08M4_RS20860 d5e69a905eb2de9897c8da45a7fbbb23 450 SUPERFAMILY SSF46689 390 443 2.51E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20860 d5e69a905eb2de9897c8da45a7fbbb23 450 SUPERFAMILY SSF52540 145 376 2.88E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16680 6ffd7f70f8ed46d7b4314ffdcb840a29 219 SUPERFAMILY SSF141371 115 217 4.58E-17 T 05-07-2017 K08M4_RS16680 6ffd7f70f8ed46d7b4314ffdcb840a29 219 Gene3D G3DSA:2.40.10.220 115 199 9.6E-6 T 05-07-2017 K08M4_RS16680 6ffd7f70f8ed46d7b4314ffdcb840a29 219 Gene3D G3DSA:2.30.110.10 7 113 5.1E-25 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 K08M4_RS16680 6ffd7f70f8ed46d7b4314ffdcb840a29 219 Pfam PF12945 Flagellar protein YcgR 33 104 2.8E-6 T 05-07-2017 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal K08M4_RS16680 6ffd7f70f8ed46d7b4314ffdcb840a29 219 Pfam PF07238 PilZ domain 113 204 4.9E-12 T 05-07-2017 IPR009875 PilZ domain GO:0035438 K08M4_RS16680 6ffd7f70f8ed46d7b4314ffdcb840a29 219 SUPERFAMILY SSF141371 5 114 1.06E-25 T 05-07-2017 K08M4_RS10295 382dae6dffce0d70d389af16f85e11c5 624 Gene3D G3DSA:1.20.1250.20 21 208 9.2E-9 T 05-07-2017 K08M4_RS10295 382dae6dffce0d70d389af16f85e11c5 624 Gene3D G3DSA:3.40.1130.10 436 568 1.9E-17 T 05-07-2017 K08M4_RS10295 382dae6dffce0d70d389af16f85e11c5 624 Pfam PF01553 Acyltransferase 442 567 1.1E-24 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 K08M4_RS10295 382dae6dffce0d70d389af16f85e11c5 624 SMART SM00563 456 570 1.6E-34 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 K08M4_RS10295 382dae6dffce0d70d389af16f85e11c5 624 Pfam PF07690 Major Facilitator Superfamily 19 383 5.1E-20 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS10295 382dae6dffce0d70d389af16f85e11c5 624 Gene3D G3DSA:1.20.1250.20 226 420 2.2E-10 T 05-07-2017 K08M4_RS10295 382dae6dffce0d70d389af16f85e11c5 624 SUPERFAMILY SSF69593 414 604 4.97E-30 T 05-07-2017 K08M4_RS10295 382dae6dffce0d70d389af16f85e11c5 624 SUPERFAMILY SSF103473 10 423 2.35E-29 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS01365 950bffdf5fa5a89e96b5a368f73b5e19 335 Gene3D G3DSA:3.40.50.1820 36 319 5.0E-28 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS01365 950bffdf5fa5a89e96b5a368f73b5e19 335 PIRSF PIRSF005211 2 335 2.1E-107 T 05-07-2017 IPR012020 AB hydrolase 4 family K08M4_RS01365 950bffdf5fa5a89e96b5a368f73b5e19 335 SUPERFAMILY SSF53474 23 310 7.08E-38 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS01365 950bffdf5fa5a89e96b5a368f73b5e19 335 Pfam PF00561 alpha/beta hydrolase fold 71 311 3.5E-16 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS13145 2d26b6cf9fd14654491460cffbd19775 191 Gene3D G3DSA:3.30.700.10 8 54 5.7E-6 T 05-07-2017 K08M4_RS13145 2d26b6cf9fd14654491460cffbd19775 191 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS13145 2d26b6cf9fd14654491460cffbd19775 191 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 28 2.9E-7 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS13145 2d26b6cf9fd14654491460cffbd19775 191 SUPERFAMILY SSF54523 8 105 1.65E-12 T 05-07-2017 K08M4_RS13145 2d26b6cf9fd14654491460cffbd19775 191 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 3 27 2.5E-7 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS20115 fac47e2a9a0794ad352bdfdba6a6ab71 347 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 176 188 - T 05-07-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 K08M4_RS20115 fac47e2a9a0794ad352bdfdba6a6ab71 347 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 9 338 1.2E-81 T 05-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 K08M4_RS20115 fac47e2a9a0794ad352bdfdba6a6ab71 347 SMART SM01240 7 344 8.4E-137 T 05-07-2017 K08M4_RS20115 fac47e2a9a0794ad352bdfdba6a6ab71 347 SUPERFAMILY SSF51412 6 336 5.89E-100 T 05-07-2017 K08M4_RS20115 fac47e2a9a0794ad352bdfdba6a6ab71 347 Gene3D G3DSA:3.20.20.70 2 343 1.4E-112 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS20115 fac47e2a9a0794ad352bdfdba6a6ab71 347 PIRSF PIRSF000235 1 347 4.8E-193 T 05-07-2017 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: R-HSA-74217 K08M4_RS20115 fac47e2a9a0794ad352bdfdba6a6ab71 347 Hamap MF_00596 GMP reductase [guaC]. 1 345 54.53 T 05-07-2017 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: R-HSA-74217 K08M4_RS20115 fac47e2a9a0794ad352bdfdba6a6ab71 347 TIGRFAM TIGR01305 GMP_reduct_1: guanosine monophosphate reductase 2 344 5.8E-183 T 05-07-2017 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: R-HSA-74217 K08M4_RS13970 cc585d4e5045ee05067596d96c0050f9 240 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 30 232 2.0E-59 T 05-07-2017 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 K08M4_RS13970 cc585d4e5045ee05067596d96c0050f9 240 Hamap MF_00521 3-deoxy-D-manno-octulosonic acid kinase [kdkA]. 1 234 36.967 T 05-07-2017 IPR022826 3-deoxy-D-manno-octulosonic acid kinase GO:0016773 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.166|MetaCyc: PWY-7675|MetaCyc: PWY-7676 K08M4_RS13970 cc585d4e5045ee05067596d96c0050f9 240 Gene3D G3DSA:1.10.510.10 147 214 1.5E-13 T 05-07-2017 K08M4_RS13970 cc585d4e5045ee05067596d96c0050f9 240 SUPERFAMILY SSF56112 46 196 4.32E-17 T 05-07-2017 IPR011009 Protein kinase-like domain K08M4_RS05795 aa08cd218f68cdc87055c832e0543b44 193 SUPERFAMILY SSF46689 4 69 4.49E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS05795 aa08cd218f68cdc87055c832e0543b44 193 Gene3D G3DSA:1.10.357.10 4 108 4.9E-23 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS05795 aa08cd218f68cdc87055c832e0543b44 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 6.2E-15 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS05795 aa08cd218f68cdc87055c832e0543b44 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 2.5E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS05795 aa08cd218f68cdc87055c832e0543b44 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 2.5E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS05570 92733741448baddcc996cbcda2ca8120 355 Pfam PF06519 TolA C-terminal 255 352 3.3E-29 T 05-07-2017 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 K08M4_RS05570 92733741448baddcc996cbcda2ca8120 355 TIGRFAM TIGR02794 tolA_full: protein TolA 13 354 3.6E-81 T 05-07-2017 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 K08M4_RS05570 92733741448baddcc996cbcda2ca8120 355 SUPERFAMILY SSF74653 263 355 5.49E-15 T 05-07-2017 K08M4_RS05570 92733741448baddcc996cbcda2ca8120 355 Gene3D G3DSA:3.30.1150.10 252 354 1.9E-21 T 05-07-2017 K08M4_RS09825 96d89df5718c4fa9467b7c7157bb2ed6 230 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS09825 96d89df5718c4fa9467b7c7157bb2ed6 230 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 5 223 6.8E-109 T 05-07-2017 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0006810|GO:0016020 K08M4_RS09825 96d89df5718c4fa9467b7c7157bb2ed6 230 SMART SM00382 33 221 6.1E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS09825 96d89df5718c4fa9467b7c7157bb2ed6 230 Pfam PF00005 ABC transporter 24 172 2.6E-34 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS09825 96d89df5718c4fa9467b7c7157bb2ed6 230 SUPERFAMILY SSF52540 5 227 1.54E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09825 96d89df5718c4fa9467b7c7157bb2ed6 230 Gene3D G3DSA:3.40.50.300 3 225 3.8E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21735 526d6aca9db814326c59eb2f5e5cd3d3 232 SMART SM00382 30 215 1.9E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS21735 526d6aca9db814326c59eb2f5e5cd3d3 232 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS21735 526d6aca9db814326c59eb2f5e5cd3d3 232 SUPERFAMILY SSF52540 1 226 5.45E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21735 526d6aca9db814326c59eb2f5e5cd3d3 232 Gene3D G3DSA:3.40.50.300 1 226 1.9E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21735 526d6aca9db814326c59eb2f5e5cd3d3 232 Pfam PF00005 ABC transporter 21 169 3.6E-33 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS18120 8e9e16350e96d36caccaca7c93a734f7 164 PIRSF PIRSF014995 2 164 8.4E-62 T 05-07-2017 IPR014469 Protein of unknown function DUF2271 K08M4_RS18120 8e9e16350e96d36caccaca7c93a734f7 164 Pfam PF10029 Predicted periplasmic protein (DUF2271) 27 159 4.1E-47 T 05-07-2017 IPR014469 Protein of unknown function DUF2271 K08M4_RS09945 776de7704de1a527fd5589c05b80dcb2 125 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 123 1.3E-57 T 05-07-2017 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 K08M4_RS09945 776de7704de1a527fd5589c05b80dcb2 125 Gene3D G3DSA:3.10.180.10 1 123 7.6E-45 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS09945 776de7704de1a527fd5589c05b80dcb2 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 121 5.8E-25 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain K08M4_RS09945 776de7704de1a527fd5589c05b80dcb2 125 SUPERFAMILY SSF54593 1 124 6.04E-38 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS09945 776de7704de1a527fd5589c05b80dcb2 125 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 05-07-2017 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 K08M4_RS01130 94269208aa0372dd9c9d1bbf32ac3d53 446 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 338 407 1.2E-4 T 05-07-2017 IPR019489 Clp ATPase, C-terminal K08M4_RS01130 94269208aa0372dd9c9d1bbf32ac3d53 446 SUPERFAMILY SSF52540 3 444 7.2E-95 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01130 94269208aa0372dd9c9d1bbf32ac3d53 446 Gene3D G3DSA:1.10.8.60 338 446 1.1E-34 T 05-07-2017 K08M4_RS01130 94269208aa0372dd9c9d1bbf32ac3d53 446 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 138 3.0E-7 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 K08M4_RS01130 94269208aa0372dd9c9d1bbf32ac3d53 446 SMART SM01086 338 437 5.4E-21 T 05-07-2017 IPR019489 Clp ATPase, C-terminal K08M4_RS01130 94269208aa0372dd9c9d1bbf32ac3d53 446 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 446 42.874 T 05-07-2017 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 K08M4_RS01130 94269208aa0372dd9c9d1bbf32ac3d53 446 Gene3D G3DSA:1.10.8.10 111 180 2.7E-34 T 05-07-2017 K08M4_RS01130 94269208aa0372dd9c9d1bbf32ac3d53 446 Gene3D G3DSA:1.10.8.10 216 246 2.7E-34 T 05-07-2017 K08M4_RS01130 94269208aa0372dd9c9d1bbf32ac3d53 446 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 4 446 2.3E-219 T 05-07-2017 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 K08M4_RS01130 94269208aa0372dd9c9d1bbf32ac3d53 446 Pfam PF07724 AAA domain (Cdc48 subfamily) 180 332 3.1E-43 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 K08M4_RS01130 94269208aa0372dd9c9d1bbf32ac3d53 446 Gene3D G3DSA:3.40.50.300 3 110 2.5E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01130 94269208aa0372dd9c9d1bbf32ac3d53 446 Gene3D G3DSA:3.40.50.300 248 334 2.5E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01130 94269208aa0372dd9c9d1bbf32ac3d53 446 SMART SM00382 49 335 1.2E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS04905 aed541c82a5beae6f81a3a64ac97a49a 114 Pfam PF01627 Hpt domain 25 99 9.6E-8 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS04905 aed541c82a5beae6f81a3a64ac97a49a 114 Gene3D G3DSA:1.20.120.160 4 111 8.3E-22 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS04905 aed541c82a5beae6f81a3a64ac97a49a 114 SUPERFAMILY SSF47226 4 110 5.5E-18 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS10550 6d70f627dd236f8fd9001d3422806e71 261 SUPERFAMILY SSF81345 2 253 9.15E-39 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS10550 6d70f627dd236f8fd9001d3422806e71 261 Pfam PF00950 ABC 3 transport family 2 257 8.0E-76 T 05-07-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 K08M4_RS10550 6d70f627dd236f8fd9001d3422806e71 261 Gene3D G3DSA:1.10.3470.10 44 237 6.6E-8 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS17570 16dc246c6da7435ab6f8090ad102dfe5 308 SUPERFAMILY SSF161098 72 141 4.06E-37 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS17570 16dc246c6da7435ab6f8090ad102dfe5 308 SUPERFAMILY SSF161098 170 292 4.06E-37 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS17570 16dc246c6da7435ab6f8090ad102dfe5 308 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 71 140 3.0E-14 T 05-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 K08M4_RS17570 16dc246c6da7435ab6f8090ad102dfe5 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 300 6.6E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS17570 16dc246c6da7435ab6f8090ad102dfe5 308 Gene3D G3DSA:1.10.3720.10 72 300 3.2E-42 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS15715 5589e0da8d45e010cfdaa29e0e9130c1 110 Gene3D G3DSA:2.60.120.10 2 105 6.7E-43 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS15715 5589e0da8d45e010cfdaa29e0e9130c1 110 Pfam PF09313 Domain of unknown function (DUF1971) 14 94 6.9E-27 T 05-07-2017 IPR015392 Domain of unknown function DUF1971 K08M4_RS15715 5589e0da8d45e010cfdaa29e0e9130c1 110 PIRSF PIRSF020632 3 110 1.3E-57 T 05-07-2017 IPR014510 Tellurite resistance predicted, YeaR K08M4_RS15715 5589e0da8d45e010cfdaa29e0e9130c1 110 SUPERFAMILY SSF51197 4 102 7.0E-33 T 05-07-2017 K08M4_RS03045 7471b6acbb540cc12c2a2689fe3bbec3 395 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 4 395 6.6E-126 T 05-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 K08M4_RS03045 7471b6acbb540cc12c2a2689fe3bbec3 395 SUPERFAMILY SSF55174 297 394 7.06E-15 T 05-07-2017 K08M4_RS03045 7471b6acbb540cc12c2a2689fe3bbec3 395 SUPERFAMILY SSF52374 6 316 5.22E-98 T 05-07-2017 K08M4_RS03045 7471b6acbb540cc12c2a2689fe3bbec3 395 Gene3D G3DSA:1.10.240.10 228 326 4.5E-37 T 05-07-2017 K08M4_RS03045 7471b6acbb540cc12c2a2689fe3bbec3 395 Pfam PF00579 tRNA synthetases class I (W and Y) 30 316 2.3E-78 T 05-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS03045 7471b6acbb540cc12c2a2689fe3bbec3 395 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 05-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS03045 7471b6acbb540cc12c2a2689fe3bbec3 395 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 178 200 3.4E-24 T 05-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 K08M4_RS03045 7471b6acbb540cc12c2a2689fe3bbec3 395 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 211 223 3.4E-24 T 05-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 K08M4_RS03045 7471b6acbb540cc12c2a2689fe3bbec3 395 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 3.4E-24 T 05-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 K08M4_RS03045 7471b6acbb540cc12c2a2689fe3bbec3 395 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 46 68 3.4E-24 T 05-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 K08M4_RS03045 7471b6acbb540cc12c2a2689fe3bbec3 395 Gene3D G3DSA:3.10.290.10 327 393 2.3E-23 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS03045 7471b6acbb540cc12c2a2689fe3bbec3 395 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 2 394 48.318 T 05-07-2017 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 K08M4_RS03045 7471b6acbb540cc12c2a2689fe3bbec3 395 Gene3D G3DSA:3.40.50.620 11 227 4.3E-82 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS08345 798fef9cc1f526c6d0d1a6561dd8b89d 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 263 7.7E-20 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS08345 798fef9cc1f526c6d0d1a6561dd8b89d 272 SUPERFAMILY SSF161098 5 271 8.78E-69 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS08345 798fef9cc1f526c6d0d1a6561dd8b89d 272 Gene3D G3DSA:1.10.3720.10 5 260 3.0E-63 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS09110 431f14e32589394b32208d3ae8cc1681 92 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 74 2.3E-9 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 K08M4_RS09110 431f14e32589394b32208d3ae8cc1681 92 SUPERFAMILY SSF54292 3 80 4.59E-18 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 K08M4_RS09110 431f14e32589394b32208d3ae8cc1681 92 Gene3D G3DSA:3.10.20.30 10 81 1.0E-16 T 05-07-2017 IPR012675 Beta-grasp domain K08M4_RS09110 431f14e32589394b32208d3ae8cc1681 92 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 35 43 - T 05-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 K08M4_RS11860 4309b7500738dd034f6d06059e37e66f 144 SMART SM00562 3 140 6.0E-92 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 K08M4_RS11860 4309b7500738dd034f6d06059e37e66f 144 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 2.4E-38 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 K08M4_RS11860 4309b7500738dd034f6d06059e37e66f 144 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 2.4E-38 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 K08M4_RS11860 4309b7500738dd034f6d06059e37e66f 144 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 2.4E-38 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 K08M4_RS11860 4309b7500738dd034f6d06059e37e66f 144 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 2.4E-38 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 K08M4_RS11860 4309b7500738dd034f6d06059e37e66f 144 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 2.4E-38 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 K08M4_RS11860 4309b7500738dd034f6d06059e37e66f 144 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 05-07-2017 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 K08M4_RS11860 4309b7500738dd034f6d06059e37e66f 144 Pfam PF00334 Nucleoside diphosphate kinase 4 138 2.3E-58 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 K08M4_RS11860 4309b7500738dd034f6d06059e37e66f 144 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 35.921 T 05-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 K08M4_RS11860 4309b7500738dd034f6d06059e37e66f 144 SUPERFAMILY SSF54919 1 140 1.7E-61 T 05-07-2017 K08M4_RS11860 4309b7500738dd034f6d06059e37e66f 144 Gene3D G3DSA:3.30.70.141 1 140 3.5E-62 T 05-07-2017 K08M4_RS16580 9ce7fe0db0c201cc61daf09ea47f350e 335 Gene3D G3DSA:1.10.10.60 286 329 2.6E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS16580 9ce7fe0db0c201cc61daf09ea47f350e 335 SMART SM00342 247 328 1.5E-9 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS16580 9ce7fe0db0c201cc61daf09ea47f350e 335 Pfam PF12833 Helix-turn-helix domain 255 330 3.1E-12 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS16580 9ce7fe0db0c201cc61daf09ea47f350e 335 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 28 195 6.0E-12 T 05-07-2017 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal K08M4_RS16580 9ce7fe0db0c201cc61daf09ea47f350e 335 SUPERFAMILY SSF46689 286 331 1.72E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS16580 9ce7fe0db0c201cc61daf09ea47f350e 335 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 312 328 1.2E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS16580 9ce7fe0db0c201cc61daf09ea47f350e 335 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 312 1.2E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS08965 b292904ebceed0df7bedd19ae6ea0d63 212 Gene3D G3DSA:1.10.10.10 125 211 5.9E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS08965 b292904ebceed0df7bedd19ae6ea0d63 212 SMART SM00448 5 118 2.6E-29 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS08965 b292904ebceed0df7bedd19ae6ea0d63 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 3.0E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS08965 b292904ebceed0df7bedd19ae6ea0d63 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 3.0E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS08965 b292904ebceed0df7bedd19ae6ea0d63 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 3.0E-13 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS08965 b292904ebceed0df7bedd19ae6ea0d63 212 SUPERFAMILY SSF52172 5 135 1.11E-34 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS08965 b292904ebceed0df7bedd19ae6ea0d63 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS08965 b292904ebceed0df7bedd19ae6ea0d63 212 Pfam PF00072 Response regulator receiver domain 7 119 3.3E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS08965 b292904ebceed0df7bedd19ae6ea0d63 212 Gene3D G3DSA:3.40.50.2300 4 124 2.4E-36 T 05-07-2017 K08M4_RS08965 b292904ebceed0df7bedd19ae6ea0d63 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 3.4E-21 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS08965 b292904ebceed0df7bedd19ae6ea0d63 212 SMART SM00421 148 205 3.5E-22 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS08965 b292904ebceed0df7bedd19ae6ea0d63 212 SUPERFAMILY SSF46894 139 211 1.09E-20 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS11455 0b2f5e381813de957ff387aaf8cb8123 412 Pfam PF00990 Diguanylate cyclase, GGDEF domain 255 400 2.2E-29 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS11455 0b2f5e381813de957ff387aaf8cb8123 412 Gene3D G3DSA:3.40.50.2300 124 250 1.5E-31 T 05-07-2017 K08M4_RS11455 0b2f5e381813de957ff387aaf8cb8123 412 Gene3D G3DSA:3.30.70.270 257 409 1.4E-35 T 05-07-2017 K08M4_RS11455 0b2f5e381813de957ff387aaf8cb8123 412 SUPERFAMILY SSF52172 125 284 5.98E-31 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS11455 0b2f5e381813de957ff387aaf8cb8123 412 Pfam PF00072 Response regulator receiver domain 5 104 2.3E-11 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS11455 0b2f5e381813de957ff387aaf8cb8123 412 Pfam PF00072 Response regulator receiver domain 127 235 3.7E-22 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS11455 0b2f5e381813de957ff387aaf8cb8123 412 Gene3D G3DSA:3.40.50.2300 4 117 6.1E-16 T 05-07-2017 K08M4_RS11455 0b2f5e381813de957ff387aaf8cb8123 412 SUPERFAMILY SSF55073 260 405 7.85E-33 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS11455 0b2f5e381813de957ff387aaf8cb8123 412 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 254 402 8.4E-35 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS11455 0b2f5e381813de957ff387aaf8cb8123 412 SMART SM00448 124 238 8.5E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS11455 0b2f5e381813de957ff387aaf8cb8123 412 SMART SM00448 3 115 4.5E-11 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS11455 0b2f5e381813de957ff387aaf8cb8123 412 SMART SM00267 244 404 6.9E-40 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS11455 0b2f5e381813de957ff387aaf8cb8123 412 SUPERFAMILY SSF52172 4 121 2.42E-18 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 893 17.463 T 05-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 Gene3D G3DSA:2.40.30.10 568 659 7.5E-22 T 05-07-2017 K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 Gene3D G3DSA:3.40.50.10050 695 774 1.5E-25 T 05-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 Gene3D G3DSA:2.40.30.10 797 894 3.7E-38 T 05-07-2017 K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 Pfam PF11987 Translation-initiation factor 2 680 785 8.6E-37 T 05-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 320 370 1.2E-14 T 05-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 51 5.6E-7 T 05-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 SUPERFAMILY SSF50447 569 650 9.56E-24 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 SUPERFAMILY SSF52156 673 802 9.29E-38 T 05-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 313 895 6.8E-283 T 05-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 ProSitePatterns PS01176 Initiation factor 2 signature. 846 868 - T 05-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 Gene3D G3DSA:3.30.56.50 2 50 6.4E-22 T 05-07-2017 K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 Pfam PF00009 Elongation factor Tu GTP binding domain 400 555 2.3E-31 T 05-07-2017 K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 SUPERFAMILY SSF50447 797 893 4.52E-33 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 398 553 6.3E-33 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 62 100 5.1E-16 T 05-07-2017 IPR013575 Initiation factor 2 associated domain, bacterial K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 SUPERFAMILY SSF46955 3 50 6.04E-12 T 05-07-2017 IPR009061 Putative DNA-binding domain K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 SUPERFAMILY SSF52540 394 560 4.3E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03125 bf01739d0fec54ee81357e115b32460d 896 Gene3D G3DSA:3.40.50.300 396 554 4.3E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11535 3b27e37c8dac8fce7180d2d4ec0e82fa 297 SUPERFAMILY SSF48179 168 290 3.03E-29 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 K08M4_RS11535 3b27e37c8dac8fce7180d2d4ec0e82fa 297 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 141 4.3E-29 T 05-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 K08M4_RS11535 3b27e37c8dac8fce7180d2d4ec0e82fa 297 SUPERFAMILY SSF51735 2 165 2.52E-50 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS11535 3b27e37c8dac8fce7180d2d4ec0e82fa 297 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 291 1.0E-75 T 05-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 K08M4_RS11535 3b27e37c8dac8fce7180d2d4ec0e82fa 297 Gene3D G3DSA:1.10.1040.10 174 291 9.4E-40 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 K08M4_RS11535 3b27e37c8dac8fce7180d2d4ec0e82fa 297 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 168 290 3.7E-34 T 05-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 K08M4_RS11535 3b27e37c8dac8fce7180d2d4ec0e82fa 297 Gene3D G3DSA:3.40.50.720 2 173 2.0E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS03590 442d3aa84b6c40c66400083affc1b3a6 219 PIRSF PIRSF016262 1 217 1.8E-63 T 05-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 K08M4_RS03590 442d3aa84b6c40c66400083affc1b3a6 219 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 74 127 1.0E-22 T 05-07-2017 K08M4_RS03590 442d3aa84b6c40c66400083affc1b3a6 219 Pfam PF03099 Biotin/lipoate A/B protein ligase family 58 158 6.7E-8 T 05-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 K08M4_RS03590 442d3aa84b6c40c66400083affc1b3a6 219 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 70 85 - T 05-07-2017 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 K08M4_RS03590 442d3aa84b6c40c66400083affc1b3a6 219 SUPERFAMILY SSF55681 3 204 4.72E-69 T 05-07-2017 K08M4_RS03590 442d3aa84b6c40c66400083affc1b3a6 219 Hamap MF_00013 Octanoyltransferase [lipB]. 4 205 37.979 T 05-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 K08M4_RS03590 442d3aa84b6c40c66400083affc1b3a6 219 Gene3D G3DSA:3.90.1550.10 3 202 4.5E-72 T 05-07-2017 K08M4_RS03590 442d3aa84b6c40c66400083affc1b3a6 219 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 27 203 1.3E-71 T 05-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 K08M4_RS05355 e35262e7375340cdf60b3b5485f43331 741 Pfam PF03971 Monomeric isocitrate dehydrogenase 7 740 0.0 T 05-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 K08M4_RS05355 e35262e7375340cdf60b3b5485f43331 741 SUPERFAMILY SSF53659 5 740 0.0 T 05-07-2017 K08M4_RS05355 e35262e7375340cdf60b3b5485f43331 741 Gene3D G3DSA:3.40.718.10 341 364 4.8E-34 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 K08M4_RS05355 e35262e7375340cdf60b3b5485f43331 741 Gene3D G3DSA:3.40.718.10 188 286 4.8E-34 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 K08M4_RS05355 e35262e7375340cdf60b3b5485f43331 741 Gene3D G3DSA:3.40.718.10 540 647 4.8E-34 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 K08M4_RS05355 e35262e7375340cdf60b3b5485f43331 741 PIRSF PIRSF009407 1 741 0.0 T 05-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 K08M4_RS05355 e35262e7375340cdf60b3b5485f43331 741 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 1 741 0.0 T 05-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 K08M4_RS04540 c73c4dbb6a3df2adfda94246ab3e53aa 337 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 319 1.4E-59 T 05-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 K08M4_RS04540 c73c4dbb6a3df2adfda94246ab3e53aa 337 Gene3D G3DSA:3.30.360.10 145 315 4.5E-79 T 05-07-2017 K08M4_RS04540 c73c4dbb6a3df2adfda94246ab3e53aa 337 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 120 7.2E-32 T 05-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 K08M4_RS04540 c73c4dbb6a3df2adfda94246ab3e53aa 337 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 6 334 5.3E-130 T 05-07-2017 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS04540 c73c4dbb6a3df2adfda94246ab3e53aa 337 SUPERFAMILY SSF51735 5 159 1.78E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04540 c73c4dbb6a3df2adfda94246ab3e53aa 337 SMART SM00859 6 121 9.2E-38 T 05-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 K08M4_RS04540 c73c4dbb6a3df2adfda94246ab3e53aa 337 SUPERFAMILY SSF55347 131 320 1.55E-76 T 05-07-2017 K08M4_RS04540 c73c4dbb6a3df2adfda94246ab3e53aa 337 PIRSF PIRSF000148 4 337 1.3E-132 T 05-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS04540 c73c4dbb6a3df2adfda94246ab3e53aa 337 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 4 333 36.024 T 05-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS04540 c73c4dbb6a3df2adfda94246ab3e53aa 337 Gene3D G3DSA:3.40.50.720 1 144 7.6E-64 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04540 c73c4dbb6a3df2adfda94246ab3e53aa 337 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 232 246 - T 05-07-2017 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS11225 9ef621744237aa77f1fef0c29ba4cd7f 281 SUPERFAMILY SSF54713 56 138 1.33E-17 T 05-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS11225 9ef621744237aa77f1fef0c29ba4cd7f 281 Hamap MF_00050 Elongation factor Ts [tsf]. 1 280 75.473 T 05-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS11225 9ef621744237aa77f1fef0c29ba4cd7f 281 Pfam PF00889 Elongation factor TS 71 261 2.2E-60 T 05-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS11225 9ef621744237aa77f1fef0c29ba4cd7f 281 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 280 2.5E-99 T 05-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS11225 9ef621744237aa77f1fef0c29ba4cd7f 281 SUPERFAMILY SSF54713 142 280 1.57E-45 T 05-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS11225 9ef621744237aa77f1fef0c29ba4cd7f 281 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 05-07-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS11225 9ef621744237aa77f1fef0c29ba4cd7f 281 Gene3D G3DSA:3.30.479.20 226 264 8.6E-26 T 05-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS11225 9ef621744237aa77f1fef0c29ba4cd7f 281 Gene3D G3DSA:3.30.479.20 165 180 8.6E-26 T 05-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS11225 9ef621744237aa77f1fef0c29ba4cd7f 281 Gene3D G3DSA:3.30.479.20 57 93 8.6E-26 T 05-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS11225 9ef621744237aa77f1fef0c29ba4cd7f 281 SUPERFAMILY SSF46934 4 54 1.22E-16 T 05-07-2017 IPR009060 UBA-like GO:0005515 K08M4_RS11225 9ef621744237aa77f1fef0c29ba4cd7f 281 Gene3D G3DSA:1.10.8.10 3 55 9.0E-25 T 05-07-2017 K08M4_RS11225 9ef621744237aa77f1fef0c29ba4cd7f 281 Gene3D G3DSA:1.10.286.20 182 225 2.2E-20 T 05-07-2017 K08M4_RS12275 05dec417dbb5bdd3af419516feec53a3 283 Pfam PF00303 Thymidylate synthase 2 283 3.7E-74 T 05-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 K08M4_RS12275 05dec417dbb5bdd3af419516feec53a3 283 ProSitePatterns PS00091 Thymidylate synthase active site. 140 168 - T 05-07-2017 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 K08M4_RS12275 05dec417dbb5bdd3af419516feec53a3 283 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 283 1.2E-42 T 05-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 K08M4_RS12275 05dec417dbb5bdd3af419516feec53a3 283 Gene3D G3DSA:3.30.572.10 2 283 3.9E-78 T 05-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 K08M4_RS12275 05dec417dbb5bdd3af419516feec53a3 283 Hamap MF_00008 Thymidylate synthase [thyA]. 1 283 32.542 T 05-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 K08M4_RS12275 05dec417dbb5bdd3af419516feec53a3 283 PRINTS PR00108 Thymidylate synthase family signature 44 65 1.8E-13 T 05-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 K08M4_RS12275 05dec417dbb5bdd3af419516feec53a3 283 PRINTS PR00108 Thymidylate synthase family signature 173 199 1.8E-13 T 05-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 K08M4_RS12275 05dec417dbb5bdd3af419516feec53a3 283 PRINTS PR00108 Thymidylate synthase family signature 211 228 1.8E-13 T 05-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 K08M4_RS12275 05dec417dbb5bdd3af419516feec53a3 283 PRINTS PR00108 Thymidylate synthase family signature 129 148 1.8E-13 T 05-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 K08M4_RS12275 05dec417dbb5bdd3af419516feec53a3 283 SUPERFAMILY SSF55831 2 283 1.16E-90 T 05-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 K08M4_RS02450 56e85fb269da4e9507e8b145994090e0 298 ProSitePatterns PS00761 Signal peptidases I signature 3. 236 249 - T 05-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 K08M4_RS02450 56e85fb269da4e9507e8b145994090e0 298 Gene3D G3DSA:2.170.230.10 153 230 5.9E-22 T 05-07-2017 IPR019766 Peptidase S26A, all-beta subdomain K08M4_RS02450 56e85fb269da4e9507e8b145994090e0 298 Pfam PF10502 Signal peptidase, peptidase S26 208 268 4.1E-8 T 05-07-2017 IPR019533 Peptidase S26 K08M4_RS02450 56e85fb269da4e9507e8b145994090e0 298 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 79 95 5.7E-27 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 K08M4_RS02450 56e85fb269da4e9507e8b145994090e0 298 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 231 250 5.7E-27 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 K08M4_RS02450 56e85fb269da4e9507e8b145994090e0 298 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 143 155 5.7E-27 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 K08M4_RS02450 56e85fb269da4e9507e8b145994090e0 298 ProSitePatterns PS00501 Signal peptidases I serine active site. 88 95 - T 05-07-2017 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 K08M4_RS02450 56e85fb269da4e9507e8b145994090e0 298 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 65 271 3.3E-45 T 05-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 K08M4_RS02450 56e85fb269da4e9507e8b145994090e0 298 SUPERFAMILY SSF51306 77 297 2.88E-68 T 05-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C K08M4_RS02450 56e85fb269da4e9507e8b145994090e0 298 Pfam PF00717 Peptidase S24-like 85 160 8.0E-20 T 05-07-2017 IPR019759 Peptidase S24/S26A/S26B K08M4_RS02450 56e85fb269da4e9507e8b145994090e0 298 ProSitePatterns PS00760 Signal peptidases I lysine active site. 145 157 - T 05-07-2017 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 K08M4_RS02450 56e85fb269da4e9507e8b145994090e0 298 Gene3D G3DSA:2.10.109.10 231 272 1.9E-54 T 05-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain K08M4_RS02450 56e85fb269da4e9507e8b145994090e0 298 Gene3D G3DSA:2.10.109.10 75 152 1.9E-54 T 05-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain K08M4_RS09255 6ad99d752b7c23edc4389274beb4b8d9 396 PIRSF PIRSF001413 1 395 1.1E-168 T 05-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 K08M4_RS09255 6ad99d752b7c23edc4389274beb4b8d9 396 SUPERFAMILY SSF53686 5 388 2.49E-141 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme K08M4_RS09255 6ad99d752b7c23edc4389274beb4b8d9 396 Gene3D G3DSA:3.40.50.1100 96 175 8.4E-23 T 05-07-2017 K08M4_RS09255 6ad99d752b7c23edc4389274beb4b8d9 396 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 51 375 3.1E-49 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme K08M4_RS09255 6ad99d752b7c23edc4389274beb4b8d9 396 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 79 93 - T 05-07-2017 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 K08M4_RS09255 6ad99d752b7c23edc4389274beb4b8d9 396 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 6 388 1.0E-194 T 05-07-2017 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 K08M4_RS09255 6ad99d752b7c23edc4389274beb4b8d9 396 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 390 49.733 T 05-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 K08M4_RS09255 6ad99d752b7c23edc4389274beb4b8d9 396 Gene3D G3DSA:3.40.50.1100 176 392 1.6E-93 T 05-07-2017 K08M4_RS01025 9799109d109264ac2e235967a1187398 407 Gene3D G3DSA:3.75.10.10 1 67 1.2E-128 T 05-07-2017 K08M4_RS01025 9799109d109264ac2e235967a1187398 407 Gene3D G3DSA:3.75.10.10 149 407 1.2E-128 T 05-07-2017 K08M4_RS01025 9799109d109264ac2e235967a1187398 407 Pfam PF02274 Amidinotransferase 18 404 7.2E-97 T 05-07-2017 K08M4_RS01025 9799109d109264ac2e235967a1187398 407 SUPERFAMILY SSF55909 3 407 7.26E-130 T 05-07-2017 K08M4_RS01025 9799109d109264ac2e235967a1187398 407 Hamap MF_00242 Arginine deiminase [arcA]. 1 407 43.627 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01025 9799109d109264ac2e235967a1187398 407 PRINTS PR01466 Bacterial arginine deiminase signature 363 377 1.6E-43 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01025 9799109d109264ac2e235967a1187398 407 PRINTS PR01466 Bacterial arginine deiminase signature 343 360 1.6E-43 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01025 9799109d109264ac2e235967a1187398 407 PRINTS PR01466 Bacterial arginine deiminase signature 2 22 1.6E-43 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01025 9799109d109264ac2e235967a1187398 407 PRINTS PR01466 Bacterial arginine deiminase signature 177 192 1.6E-43 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01025 9799109d109264ac2e235967a1187398 407 PRINTS PR01466 Bacterial arginine deiminase signature 386 404 1.6E-43 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01025 9799109d109264ac2e235967a1187398 407 PRINTS PR01466 Bacterial arginine deiminase signature 149 167 1.6E-43 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01025 9799109d109264ac2e235967a1187398 407 TIGRFAM TIGR01078 arcA: arginine deiminase 5 407 2.4E-161 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01025 9799109d109264ac2e235967a1187398 407 PIRSF PIRSF006356 1 407 3.1E-149 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS17040 45f6d22290d8d36cd91d3a1f36add687 131 Pfam PF07361 Cytochrome b562 26 121 1.0E-24 T 05-07-2017 IPR009155 Cytochrome b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900|GO:0042597 K08M4_RS17040 45f6d22290d8d36cd91d3a1f36add687 131 Gene3D G3DSA:1.20.120.10 25 122 1.5E-29 T 05-07-2017 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 K08M4_RS17040 45f6d22290d8d36cd91d3a1f36add687 131 SUPERFAMILY SSF47175 26 121 1.88E-22 T 05-07-2017 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 K08M4_RS15360 4226a81679f95279295bd06cdde5cf97 235 Pfam PF07702 UTRA domain 86 208 2.5E-19 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 K08M4_RS15360 4226a81679f95279295bd06cdde5cf97 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 64 5.2E-13 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS15360 4226a81679f95279295bd06cdde5cf97 235 SUPERFAMILY SSF46785 2 66 1.59E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15360 4226a81679f95279295bd06cdde5cf97 235 SMART SM00866 81 219 2.8E-7 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 K08M4_RS15360 4226a81679f95279295bd06cdde5cf97 235 Gene3D G3DSA:3.40.1410.10 59 222 7.0E-29 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain K08M4_RS15360 4226a81679f95279295bd06cdde5cf97 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 54 3.5E-10 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS15360 4226a81679f95279295bd06cdde5cf97 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 24 38 3.5E-10 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS15360 4226a81679f95279295bd06cdde5cf97 235 Gene3D G3DSA:1.10.10.10 1 58 4.8E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15360 4226a81679f95279295bd06cdde5cf97 235 SMART SM00345 7 64 8.9E-12 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS15360 4226a81679f95279295bd06cdde5cf97 235 SUPERFAMILY SSF64288 88 225 5.02E-29 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain K08M4_RS19390 45f83cd8df4266522b8c90589dc259df 487 Gene3D G3DSA:3.40.605.10 12 269 1.1E-83 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS19390 45f83cd8df4266522b8c90589dc259df 487 Gene3D G3DSA:3.40.309.10 270 457 5.7E-56 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 K08M4_RS19390 45f83cd8df4266522b8c90589dc259df 487 SUPERFAMILY SSF53720 8 485 9.56E-147 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 K08M4_RS19390 45f83cd8df4266522b8c90589dc259df 487 Pfam PF00171 Aldehyde dehydrogenase family 23 481 9.1E-149 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS18275 e877dc871d9250384b34ae7fc8da2274 172 Pfam PF10029 Predicted periplasmic protein (DUF2271) 31 163 4.8E-47 T 05-07-2017 IPR014469 Protein of unknown function DUF2271 K08M4_RS18275 e877dc871d9250384b34ae7fc8da2274 172 PIRSF PIRSF014995 1 172 3.5E-62 T 05-07-2017 IPR014469 Protein of unknown function DUF2271 K08M4_RS09820 698361edca4056d486387b662f4acdc5 414 Pfam PF12704 MacB-like periplasmic core domain 30 241 1.3E-13 T 05-07-2017 IPR025857 MacB-like periplasmic core domain K08M4_RS09820 698361edca4056d486387b662f4acdc5 414 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 5 413 5.8E-155 T 05-07-2017 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 K08M4_RS09820 698361edca4056d486387b662f4acdc5 414 Pfam PF02687 FtsX-like permease family 274 407 4.0E-20 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 K08M4_RS09820 698361edca4056d486387b662f4acdc5 414 TIGRFAM TIGR02213 lolE_release: lipoprotein releasing system, transmembrane protein LolE 4 414 9.1E-210 T 05-07-2017 IPR011926 Lipoprotein-releasing system transmembrane protein LolC/E, gammaproteobacteria type GO:0006810|GO:0009276|GO:0016021 K08M4_RS21665 5f6358b27e7108bad89d51094dfbf93d 402 Gene3D G3DSA:1.20.1250.20 198 391 2.5E-14 T 05-07-2017 K08M4_RS21665 5f6358b27e7108bad89d51094dfbf93d 402 Pfam PF07690 Major Facilitator Superfamily 19 228 3.6E-25 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS21665 5f6358b27e7108bad89d51094dfbf93d 402 Gene3D G3DSA:1.20.1250.20 14 191 9.9E-30 T 05-07-2017 K08M4_RS21665 5f6358b27e7108bad89d51094dfbf93d 402 SUPERFAMILY SSF103473 12 391 8.5E-59 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS05415 b0348412fbe746b2d45f4ed5d4f2c66d 484 Pfam PF08323 Starch synthase catalytic domain 8 238 5.6E-68 T 05-07-2017 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 K08M4_RS05415 b0348412fbe746b2d45f4ed5d4f2c66d 484 Gene3D G3DSA:3.40.50.2000 256 465 1.4E-63 T 05-07-2017 K08M4_RS05415 b0348412fbe746b2d45f4ed5d4f2c66d 484 Hamap MF_00484 Glycogen synthase [glgA]. 6 483 39.324 T 05-07-2017 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 K08M4_RS05415 b0348412fbe746b2d45f4ed5d4f2c66d 484 Pfam PF00534 Glycosyl transferases group 1 302 441 7.7E-15 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 K08M4_RS05415 b0348412fbe746b2d45f4ed5d4f2c66d 484 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 7 482 5.9E-163 T 05-07-2017 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 K08M4_RS05415 b0348412fbe746b2d45f4ed5d4f2c66d 484 SUPERFAMILY SSF53756 6 483 1.57E-110 T 05-07-2017 K08M4_RS17160 8d38692d56233ce0c63efdcca56838f8 298 Gene3D G3DSA:1.20.1510.10 10 214 1.8E-30 T 05-07-2017 IPR027469 Cation efflux protein transmembrane domain K08M4_RS17160 8d38692d56233ce0c63efdcca56838f8 298 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 10 279 2.6E-31 T 05-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 K08M4_RS17160 8d38692d56233ce0c63efdcca56838f8 298 Pfam PF01545 Cation efflux family 14 214 1.6E-37 T 05-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 K08M4_RS17160 8d38692d56233ce0c63efdcca56838f8 298 SUPERFAMILY SSF161111 7 214 3.14E-37 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 4 86 2.5E-26 T 05-07-2017 IPR021993 Putative metal-binding domain of cation transport ATPase K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 Gene3D G3DSA:3.40.50.1000 603 751 5.8E-44 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 Gene3D G3DSA:3.40.50.1000 475 517 5.8E-44 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 353 367 7.2E-25 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 630 640 7.2E-25 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 501 515 7.2E-25 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 682 701 7.2E-25 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 705 717 7.2E-25 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 SUPERFAMILY SSF81653 318 402 1.7E-22 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 PRINTS PR00943 Copper-transporting ATPase signature 423 437 2.1E-5 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 PRINTS PR00943 Copper-transporting ATPase signature 135 155 2.1E-5 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 PRINTS PR00943 Copper-transporting ATPase signature 296 314 2.1E-5 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 PRINTS PR00943 Copper-transporting ATPase signature 660 677 2.1E-5 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 PRINTS PR00943 Copper-transporting ATPase signature 230 249 2.1E-5 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 ProSitePatterns PS01229 Hypothetical cof family signature 2. 682 704 - T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 Pfam PF00403 Heavy-metal-associated domain 93 154 5.7E-9 T 05-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 SUPERFAMILY SSF56784 500 519 3.73E-46 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 SUPERFAMILY SSF56784 554 782 3.73E-46 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 503 509 - T 05-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 228 784 1.2E-153 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 SUPERFAMILY SSF81665 727 767 2.48E-11 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 SUPERFAMILY SSF81665 404 495 2.48E-11 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 SUPERFAMILY SSF81665 249 267 2.48E-11 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 Gene3D G3DSA:2.70.150.10 249 402 6.5E-25 T 05-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 SUPERFAMILY SSF55008 85 162 1.28E-17 T 05-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 273 786 3.8E-124 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 Pfam PF00702 haloacid dehalogenase-like hydrolase 497 695 3.5E-29 T 05-07-2017 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 245 784 4.2E-161 T 05-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 279 762 4.6E-74 T 05-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 Pfam PF00122 E1-E2 ATPase 278 492 2.9E-54 T 05-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 K08M4_RS07640 c7c3464683adca9ed2d1ffef635caa0f 790 Gene3D G3DSA:3.30.70.100 87 159 1.3E-17 T 05-07-2017 K08M4_RS17650 b130d2432d9092847653f8d6d5e00bdd 84 ProDom PD058023 TRANSMEMBRANE SO1069 MEMBRANE VCA0743 SO4196 VVA0623 VPA0666 HI1736 PM0424 4 67 2.0E-28 T 05-07-2017 IPR020137 Uncharacterised protein family HI1736 K08M4_RS17650 b130d2432d9092847653f8d6d5e00bdd 84 Pfam PF10688 Bacterial inner membrane protein 5 73 4.3E-8 T 05-07-2017 IPR019629 Uncharacterised protein family HI1736/YgjV K08M4_RS03220 dd0a89849d8b83b1ea2bb8b2a03eaa08 270 SUPERFAMILY SSF51556 10 268 7.88E-72 T 05-07-2017 IPR032466 Metal-dependent hydrolase K08M4_RS03220 dd0a89849d8b83b1ea2bb8b2a03eaa08 270 Gene3D G3DSA:3.20.20.140 4 268 2.8E-75 T 05-07-2017 K08M4_RS03220 dd0a89849d8b83b1ea2bb8b2a03eaa08 270 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 203 219 - T 05-07-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 K08M4_RS03220 dd0a89849d8b83b1ea2bb8b2a03eaa08 270 Pfam PF01026 TatD related DNase 11 266 1.1E-63 T 05-07-2017 IPR001130 TatD family GO:0016788 K08M4_RS03220 dd0a89849d8b83b1ea2bb8b2a03eaa08 270 PIRSF PIRSF005902 1 270 3.1E-68 T 05-07-2017 IPR001130 TatD family GO:0016788 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 6.7E-52 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 6.7E-52 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 6.7E-52 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 PRINTS PR00985 Leucyl-tRNA synthetase signature 523 545 6.7E-52 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 6.7E-52 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 PRINTS PR00985 Leucyl-tRNA synthetase signature 556 566 6.7E-52 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 6.7E-52 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 SUPERFAMILY SSF47323 661 857 3.74E-33 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 Gene3D G3DSA:1.10.730.10 647 793 2.7E-45 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 857 23.367 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 172 1.4E-26 T 05-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 618 650 1.4E-7 T 05-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 418 572 7.3E-10 T 05-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 857 0.0 T 05-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 SUPERFAMILY SSF50677 226 415 8.58E-58 T 05-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 404 7.9E-79 T 05-07-2017 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 Pfam PF08264 Anticodon-binding domain of tRNA 699 820 2.3E-16 T 05-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 SUPERFAMILY SSF52374 4 226 1.92E-147 T 05-07-2017 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 SUPERFAMILY SSF52374 416 667 1.92E-147 T 05-07-2017 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 Gene3D G3DSA:3.40.50.620 4 222 5.5E-156 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 Gene3D G3DSA:3.40.50.620 425 572 5.5E-156 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 Gene3D G3DSA:3.40.50.620 617 646 5.5E-156 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 05-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS03640 f2870e17c4be45024d11f295171c1665 858 Gene3D G3DSA:3.90.740.10 223 424 1.1E-57 T 05-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 K08M4_RS05875 f2153926e691e833d50c9c40285c32fc 395 SUPERFAMILY SSF54631 274 392 3.93E-14 T 05-07-2017 K08M4_RS05875 f2153926e691e833d50c9c40285c32fc 395 Gene3D G3DSA:3.40.50.300 2 264 1.2E-79 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05875 f2153926e691e833d50c9c40285c32fc 395 Pfam PF00005 ABC transporter 45 192 1.3E-34 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS05875 f2153926e691e833d50c9c40285c32fc 395 Pfam PF00571 CBS domain 348 393 9.8E-6 T 05-07-2017 IPR000644 CBS domain K08M4_RS05875 f2153926e691e833d50c9c40285c32fc 395 SMART SM00382 53 242 7.7E-18 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS05875 f2153926e691e833d50c9c40285c32fc 395 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS05875 f2153926e691e833d50c9c40285c32fc 395 Gene3D G3DSA:3.10.580.10 273 394 4.1E-19 T 05-07-2017 K08M4_RS05875 f2153926e691e833d50c9c40285c32fc 395 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 37 393 2.5E-153 T 05-07-2017 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 K08M4_RS05875 f2153926e691e833d50c9c40285c32fc 395 SUPERFAMILY SSF52540 37 271 1.4E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09790 623fc8d368404f64f04399f0c18a0a8f 248 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 1 241 8.4E-113 T 05-07-2017 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 K08M4_RS09790 623fc8d368404f64f04399f0c18a0a8f 248 Hamap MF_00057 3-deoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 248 46.313 T 05-07-2017 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 K08M4_RS09790 623fc8d368404f64f04399f0c18a0a8f 248 SUPERFAMILY SSF53448 3 246 5.86E-66 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS09790 623fc8d368404f64f04399f0c18a0a8f 248 Gene3D G3DSA:3.90.550.10 1 247 8.4E-86 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS09790 623fc8d368404f64f04399f0c18a0a8f 248 Pfam PF02348 Cytidylyltransferase 5 221 3.1E-64 T 05-07-2017 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 K08M4_RS01210 0ffc770b9be1153f1600fa31f890b7e6 403 Gene3D G3DSA:3.40.50.620 7 175 2.3E-62 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS01210 0ffc770b9be1153f1600fa31f890b7e6 403 Gene3D G3DSA:3.90.1260.10 179 402 2.5E-88 T 05-07-2017 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01210 0ffc770b9be1153f1600fa31f890b7e6 403 SUPERFAMILY SSF52402 7 170 1.21E-47 T 05-07-2017 K08M4_RS01210 0ffc770b9be1153f1600fa31f890b7e6 403 Pfam PF00764 Arginosuccinate synthase 10 396 4.3E-146 T 05-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01210 0ffc770b9be1153f1600fa31f890b7e6 403 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 121 132 - T 05-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01210 0ffc770b9be1153f1600fa31f890b7e6 403 TIGRFAM TIGR00032 argG: argininosuccinate synthase 8 395 4.1E-136 T 05-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01210 0ffc770b9be1153f1600fa31f890b7e6 403 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 12 20 - T 05-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01210 0ffc770b9be1153f1600fa31f890b7e6 403 Hamap MF_00005 Argininosuccinate synthase [argG]. 6 402 51.84 T 05-07-2017 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01210 0ffc770b9be1153f1600fa31f890b7e6 403 SUPERFAMILY SSF69864 177 402 4.45E-88 T 05-07-2017 K08M4_RS08215 0fd656547bee1bdae675ff6cc66e12ae 125 TIGRFAM TIGR00526 folB_dom: FolB domain 6 119 4.6E-29 T 05-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS08215 0fd656547bee1bdae675ff6cc66e12ae 125 SMART SM00905 7 117 6.0E-32 T 05-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS08215 0fd656547bee1bdae675ff6cc66e12ae 125 SUPERFAMILY SSF55620 4 116 3.89E-29 T 05-07-2017 K08M4_RS08215 0fd656547bee1bdae675ff6cc66e12ae 125 Gene3D G3DSA:3.30.1130.10 2 117 1.6E-35 T 05-07-2017 K08M4_RS08215 0fd656547bee1bdae675ff6cc66e12ae 125 Pfam PF02152 Dihydroneopterin aldolase 7 115 1.5E-26 T 05-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS13470 315b347d4f0599eb94fd957bac324b7f 137 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 9.0E-37 T 05-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13470 315b347d4f0599eb94fd957bac324b7f 137 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.519 T 05-07-2017 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 K08M4_RS13470 315b347d4f0599eb94fd957bac324b7f 137 Pfam PF01250 Ribosomal protein S6 3 91 2.1E-27 T 05-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13470 315b347d4f0599eb94fd957bac324b7f 137 Gene3D G3DSA:3.30.70.60 1 103 3.9E-41 T 05-07-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 K08M4_RS13470 315b347d4f0599eb94fd957bac324b7f 137 SUPERFAMILY SSF54995 1 103 1.1E-37 T 05-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS20500 2e423487e40844e3206f9ca9fb8c9e5b 262 Gene3D G3DSA:3.60.15.10 4 221 9.0E-32 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS20500 2e423487e40844e3206f9ca9fb8c9e5b 262 SMART SM00849 10 209 3.5E-17 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS20500 2e423487e40844e3206f9ca9fb8c9e5b 262 Pfam PF00753 Metallo-beta-lactamase superfamily 10 196 1.4E-16 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS20500 2e423487e40844e3206f9ca9fb8c9e5b 262 SUPERFAMILY SSF56281 13 243 1.7E-34 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS17005 2da336925711746ae2610a6a83e71294 587 Pfam PF00005 ABC transporter 357 505 3.9E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS17005 2da336925711746ae2610a6a83e71294 587 Gene3D G3DSA:3.40.50.300 341 583 1.5E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17005 2da336925711746ae2610a6a83e71294 587 SUPERFAMILY SSF52540 339 578 1.05E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17005 2da336925711746ae2610a6a83e71294 587 SMART SM00382 366 554 3.1E-7 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS17005 2da336925711746ae2610a6a83e71294 587 Gene3D G3DSA:1.20.1560.10 8 320 2.7E-49 T 05-07-2017 K08M4_RS17005 2da336925711746ae2610a6a83e71294 587 Pfam PF00664 ABC transporter transmembrane region 19 291 5.7E-28 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS17005 2da336925711746ae2610a6a83e71294 587 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS17005 2da336925711746ae2610a6a83e71294 587 SUPERFAMILY SSF90123 7 321 4.19E-53 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS15015 9566a6f80973eaa44ae73c104952f21a 249 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 25 243 2.6E-56 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS15015 9566a6f80973eaa44ae73c104952f21a 249 SUPERFAMILY SSF53850 21 246 7.25E-58 T 05-07-2017 K08M4_RS15015 9566a6f80973eaa44ae73c104952f21a 249 Gene3D G3DSA:3.40.190.10 101 200 1.0E-27 T 05-07-2017 K08M4_RS15015 9566a6f80973eaa44ae73c104952f21a 249 SMART SM00079 24 244 0.0034 T 05-07-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 K08M4_RS15015 9566a6f80973eaa44ae73c104952f21a 249 Gene3D G3DSA:3.40.190.10 203 247 2.8E-35 T 05-07-2017 K08M4_RS15015 9566a6f80973eaa44ae73c104952f21a 249 Gene3D G3DSA:3.40.190.10 22 100 2.8E-35 T 05-07-2017 K08M4_RS15015 9566a6f80973eaa44ae73c104952f21a 249 SMART SM00062 24 245 9.1E-75 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS15015 9566a6f80973eaa44ae73c104952f21a 249 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 46 59 - T 05-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 K08M4_RS00890 aec59704c65fd10ed1bcd81686185b21 536 SMART SM00851 19 132 8.6E-60 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain K08M4_RS00890 aec59704c65fd10ed1bcd81686185b21 536 SMART SM00798 137 468 1.0E-216 T 05-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 K08M4_RS00890 aec59704c65fd10ed1bcd81686185b21 536 Gene3D G3DSA:3.40.140.20 260 379 1.1E-50 T 05-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 K08M4_RS00890 aec59704c65fd10ed1bcd81686185b21 536 SUPERFAMILY SSF53927 228 536 2.11E-130 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 K08M4_RS00890 aec59704c65fd10ed1bcd81686185b21 536 Pfam PF01808 AICARFT/IMPCHase bienzyme 137 467 5.0E-120 T 05-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 K08M4_RS00890 aec59704c65fd10ed1bcd81686185b21 536 Gene3D G3DSA:3.40.50.1380 5 190 1.6E-86 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain K08M4_RS00890 aec59704c65fd10ed1bcd81686185b21 536 SUPERFAMILY SSF52335 7 197 1.44E-71 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain K08M4_RS00890 aec59704c65fd10ed1bcd81686185b21 536 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 7 536 45.786 T 05-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 K08M4_RS00890 aec59704c65fd10ed1bcd81686185b21 536 Pfam PF02142 MGS-like domain 19 132 8.9E-31 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain K08M4_RS00890 aec59704c65fd10ed1bcd81686185b21 536 PIRSF PIRSF000414 1 536 4.0E-228 T 05-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 K08M4_RS00890 aec59704c65fd10ed1bcd81686185b21 536 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 8 536 2.1E-258 T 05-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 K08M4_RS00890 aec59704c65fd10ed1bcd81686185b21 536 Gene3D G3DSA:3.40.140.20 384 526 1.5E-60 T 05-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 K08M4_RS16345 b29998b2bd1954ffa56a0e3b7715ef1d 296 SUPERFAMILY SSF53807 37 295 4.32E-46 T 05-07-2017 K08M4_RS16345 b29998b2bd1954ffa56a0e3b7715ef1d 296 Gene3D G3DSA:3.40.50.1980 152 294 5.3E-20 T 05-07-2017 K08M4_RS16345 b29998b2bd1954ffa56a0e3b7715ef1d 296 Pfam PF01497 Periplasmic binding protein 41 271 3.7E-39 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 K08M4_RS16345 b29998b2bd1954ffa56a0e3b7715ef1d 296 Gene3D G3DSA:3.40.50.1980 38 151 2.0E-19 T 05-07-2017 K08M4_RS14330 f56ca97480d4bc335ff246f9ef869b9a 871 SMART SM00052 590 837 1.0E-100 T 05-07-2017 IPR001633 EAL domain K08M4_RS14330 f56ca97480d4bc335ff246f9ef869b9a 871 Pfam PF00672 HAMP domain 348 416 3.9E-9 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS14330 f56ca97480d4bc335ff246f9ef869b9a 871 Pfam PF00990 Diguanylate cyclase, GGDEF domain 427 574 2.8E-27 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS14330 f56ca97480d4bc335ff246f9ef869b9a 871 Gene3D G3DSA:3.30.70.270 428 586 7.1E-34 T 05-07-2017 K08M4_RS14330 f56ca97480d4bc335ff246f9ef869b9a 871 Pfam PF02743 Cache domain 49 311 1.5E-19 T 05-07-2017 IPR033479 Double Cache domain 1 K08M4_RS14330 f56ca97480d4bc335ff246f9ef869b9a 871 SMART SM00267 415 580 6.1E-30 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS14330 f56ca97480d4bc335ff246f9ef869b9a 871 Gene3D G3DSA:3.30.450.20 89 218 1.0E-18 T 05-07-2017 K08M4_RS14330 f56ca97480d4bc335ff246f9ef869b9a 871 SUPERFAMILY SSF158472 368 417 1.16E-8 T 05-07-2017 K08M4_RS14330 f56ca97480d4bc335ff246f9ef869b9a 871 Gene3D G3DSA:3.20.20.450 595 839 1.9E-89 T 05-07-2017 IPR001633 EAL domain K08M4_RS14330 f56ca97480d4bc335ff246f9ef869b9a 871 Pfam PF00563 EAL domain 596 832 1.0E-71 T 05-07-2017 IPR001633 EAL domain K08M4_RS14330 f56ca97480d4bc335ff246f9ef869b9a 871 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 422 576 4.0E-22 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS14330 f56ca97480d4bc335ff246f9ef869b9a 871 SMART SM00304 367 420 6.3E-8 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS14330 f56ca97480d4bc335ff246f9ef869b9a 871 SUPERFAMILY SSF141868 597 840 6.8E-82 T 05-07-2017 IPR001633 EAL domain K08M4_RS14330 f56ca97480d4bc335ff246f9ef869b9a 871 SUPERFAMILY SSF55073 431 575 1.18E-29 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS04960 63afb82a2a4588df4756d2dd9002bdd5 300 SUPERFAMILY SSF161098 98 281 1.7E-26 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS04960 63afb82a2a4588df4756d2dd9002bdd5 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 24 69 2.1E-14 T 05-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain K08M4_RS04960 63afb82a2a4588df4756d2dd9002bdd5 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 298 1.7E-27 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS04960 63afb82a2a4588df4756d2dd9002bdd5 300 Gene3D G3DSA:1.10.3720.10 100 297 1.1E-25 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS14795 af39b485f66d0353ad2ca603521aa361 321 Gene3D G3DSA:3.10.25.10 210 313 2.7E-33 T 05-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 K08M4_RS14795 af39b485f66d0353ad2ca603521aa361 321 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 136 159 - T 05-07-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 K08M4_RS14795 af39b485f66d0353ad2ca603521aa361 321 SUPERFAMILY SSF53328 5 207 2.22E-66 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 K08M4_RS14795 af39b485f66d0353ad2ca603521aa361 321 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 5 317 4.2E-107 T 05-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 K08M4_RS14795 af39b485f66d0353ad2ca603521aa361 321 Pfam PF02911 Formyl transferase, C-terminal domain 207 309 3.8E-28 T 05-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 K08M4_RS14795 af39b485f66d0353ad2ca603521aa361 321 Gene3D G3DSA:3.40.50.170 4 208 2.6E-74 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 K08M4_RS14795 af39b485f66d0353ad2ca603521aa361 321 Pfam PF00551 Formyl transferase 6 183 4.5E-47 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 K08M4_RS14795 af39b485f66d0353ad2ca603521aa361 321 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 5 312 37.249 T 05-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 K08M4_RS14795 af39b485f66d0353ad2ca603521aa361 321 SUPERFAMILY SSF50486 208 316 5.89E-30 T 05-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 K08M4_RS11550 ea6a1d92e8617a6ce8325c6a66ae8af1 269 SUPERFAMILY SSF69572 9 266 9.94E-62 T 05-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 K08M4_RS11550 ea6a1d92e8617a6ce8325c6a66ae8af1 269 Pfam PF00899 ThiF family 24 198 8.6E-38 T 05-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 K08M4_RS11550 ea6a1d92e8617a6ce8325c6a66ae8af1 269 Gene3D G3DSA:3.40.50.720 6 266 1.2E-53 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS03835 0875b1e61a2a9cc697749571093dbdc9 553 ProSitePatterns PS00786 5'-nucleotidase signature 2. 113 124 - T 05-07-2017 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS03835 0875b1e61a2a9cc697749571093dbdc9 553 Pfam PF00149 Calcineurin-like phosphoesterase 38 259 4.1E-22 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 K08M4_RS03835 0875b1e61a2a9cc697749571093dbdc9 553 PRINTS PR01607 Apyrase family signature 242 265 7.3E-51 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS03835 0875b1e61a2a9cc697749571093dbdc9 553 PRINTS PR01607 Apyrase family signature 487 506 7.3E-51 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS03835 0875b1e61a2a9cc697749571093dbdc9 553 PRINTS PR01607 Apyrase family signature 420 443 7.3E-51 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS03835 0875b1e61a2a9cc697749571093dbdc9 553 PRINTS PR01607 Apyrase family signature 36 54 7.3E-51 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS03835 0875b1e61a2a9cc697749571093dbdc9 553 PRINTS PR01607 Apyrase family signature 211 228 7.3E-51 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS03835 0875b1e61a2a9cc697749571093dbdc9 553 PRINTS PR01607 Apyrase family signature 287 307 7.3E-51 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS03835 0875b1e61a2a9cc697749571093dbdc9 553 SUPERFAMILY SSF56300 32 363 4.0E-98 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS03835 0875b1e61a2a9cc697749571093dbdc9 553 SUPERFAMILY SSF55816 367 543 2.75E-52 T 05-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS03835 0875b1e61a2a9cc697749571093dbdc9 553 Gene3D G3DSA:3.90.780.10 367 542 3.5E-52 T 05-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS03835 0875b1e61a2a9cc697749571093dbdc9 553 Pfam PF02872 5'-nucleotidase, C-terminal domain 367 513 8.4E-34 T 05-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS03835 0875b1e61a2a9cc697749571093dbdc9 553 ProSitePatterns PS00785 5'-nucleotidase signature 1. 38 50 - T 05-07-2017 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS03835 0875b1e61a2a9cc697749571093dbdc9 553 Gene3D G3DSA:3.60.21.10 32 364 4.9E-102 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS02390 81d6f12a03d250941b983566be14de66 407 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 295 308 - T 05-07-2017 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 K08M4_RS02390 81d6f12a03d250941b983566be14de66 407 Gene3D G3DSA:3.50.50.60 279 316 5.7E-47 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02390 81d6f12a03d250941b983566be14de66 407 Gene3D G3DSA:3.50.50.60 1 180 5.7E-47 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02390 81d6f12a03d250941b983566be14de66 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 4.2E-20 T 05-07-2017 K08M4_RS02390 81d6f12a03d250941b983566be14de66 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 4.2E-20 T 05-07-2017 K08M4_RS02390 81d6f12a03d250941b983566be14de66 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 4.2E-20 T 05-07-2017 K08M4_RS02390 81d6f12a03d250941b983566be14de66 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 4.2E-20 T 05-07-2017 K08M4_RS02390 81d6f12a03d250941b983566be14de66 407 Pfam PF01494 FAD binding domain 5 347 1.4E-30 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 K08M4_RS02390 81d6f12a03d250941b983566be14de66 407 SUPERFAMILY SSF51905 268 385 8.2E-61 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02390 81d6f12a03d250941b983566be14de66 407 SUPERFAMILY SSF51905 5 177 8.2E-61 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02390 81d6f12a03d250941b983566be14de66 407 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 6 391 7.2E-137 T 05-07-2017 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 K08M4_RS14310 ff2578afb418bb4df7d370dff29af00d 469 Pfam PF00120 Glutamine synthetase, catalytic domain 103 466 3.1E-136 T 05-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 K08M4_RS14310 ff2578afb418bb4df7d370dff29af00d 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 05-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 K08M4_RS14310 ff2578afb418bb4df7d370dff29af00d 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 4 468 4.4E-207 T 05-07-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 K08M4_RS14310 ff2578afb418bb4df7d370dff29af00d 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 50 68 - T 05-07-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 K08M4_RS14310 ff2578afb418bb4df7d370dff29af00d 469 Gene3D G3DSA:3.10.20.70 3 105 1.0E-38 T 05-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 K08M4_RS14310 ff2578afb418bb4df7d370dff29af00d 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 386 398 - T 05-07-2017 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 K08M4_RS14310 ff2578afb418bb4df7d370dff29af00d 469 Gene3D G3DSA:3.30.590.10 106 455 1.1E-137 T 05-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 K08M4_RS14310 ff2578afb418bb4df7d370dff29af00d 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 95 5.3E-30 T 05-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 K08M4_RS14310 ff2578afb418bb4df7d370dff29af00d 469 SMART SM01230 102 379 1.2E-150 T 05-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 K08M4_RS14310 ff2578afb418bb4df7d370dff29af00d 469 SUPERFAMILY SSF55931 102 468 5.3E-136 T 05-07-2017 K08M4_RS14310 ff2578afb418bb4df7d370dff29af00d 469 SUPERFAMILY SSF54368 3 100 1.07E-34 T 05-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 57 499 5.9E-150 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 48 73 1.0E-121 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 122 146 1.0E-121 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 165 177 1.0E-121 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 380 398 1.0E-121 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 345 366 1.0E-121 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 458 479 1.0E-121 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 224 243 1.0E-121 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 95 118 1.0E-121 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 275 296 1.0E-121 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 321 336 1.0E-121 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 408 427 1.0E-121 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 PRINTS PR01165 Cytochrome c oxidase subunit I signature 195 213 1.0E-121 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 49 552 7.2E-213 T 05-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 277 331 - T 05-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 SUPERFAMILY SSF81442 45 552 6.93E-192 T 05-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16725 3c16254d17a593e7b7c25747d083c40a 553 Gene3D G3DSA:1.20.210.10 37 552 7.6E-216 T 05-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS04395 a486c9c14027433893f20ce7aacd1d65 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 234 7.7E-15 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS04395 a486c9c14027433893f20ce7aacd1d65 242 Pfam PF00072 Response regulator receiver domain 7 117 3.4E-29 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS04395 a486c9c14027433893f20ce7aacd1d65 242 Gene3D G3DSA:3.40.50.2300 3 131 8.4E-42 T 05-07-2017 K08M4_RS04395 a486c9c14027433893f20ce7aacd1d65 242 SMART SM00448 5 116 5.6E-43 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS04395 a486c9c14027433893f20ce7aacd1d65 242 SMART SM00862 158 234 1.3E-11 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS04395 a486c9c14027433893f20ce7aacd1d65 242 SUPERFAMILY SSF46894 138 235 4.54E-20 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS04395 a486c9c14027433893f20ce7aacd1d65 242 SUPERFAMILY SSF52172 2 128 4.98E-42 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS04395 a486c9c14027433893f20ce7aacd1d65 242 Gene3D G3DSA:1.10.10.10 136 237 5.5E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06585 7c3ae8b1c47fc60f01afc2e832a11022 252 SMART SM00382 22 214 1.5E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS06585 7c3ae8b1c47fc60f01afc2e832a11022 252 Gene3D G3DSA:3.40.50.300 16 235 4.8E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06585 7c3ae8b1c47fc60f01afc2e832a11022 252 Pfam PF00005 ABC transporter 15 165 1.3E-23 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS06585 7c3ae8b1c47fc60f01afc2e832a11022 252 SUPERFAMILY SSF52540 16 230 3.93E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06585 7c3ae8b1c47fc60f01afc2e832a11022 252 Hamap MF_01005 Vitamin B12 import ATP-binding protein BtuD [btuD]. 1 252 45.429 T 05-07-2017 IPR023693 ABC transporter, vitamin B12, BtuD GO:0005524|GO:0015889|GO:0016887 K08M4_RS17400 97322dbe2555c561a5aca6e757376574 311 Gene3D G3DSA:3.40.50.1980 44 133 4.7E-30 T 05-07-2017 K08M4_RS17400 97322dbe2555c561a5aca6e757376574 311 Pfam PF01497 Periplasmic binding protein 50 280 2.0E-23 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 K08M4_RS17400 97322dbe2555c561a5aca6e757376574 311 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 98 113 7.8E-6 T 05-07-2017 IPR008091 Ferrichrome-binding periplasmic protein K08M4_RS17400 97322dbe2555c561a5aca6e757376574 311 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 67 85 7.8E-6 T 05-07-2017 IPR008091 Ferrichrome-binding periplasmic protein K08M4_RS17400 97322dbe2555c561a5aca6e757376574 311 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 287 300 7.8E-6 T 05-07-2017 IPR008091 Ferrichrome-binding periplasmic protein K08M4_RS17400 97322dbe2555c561a5aca6e757376574 311 Gene3D G3DSA:3.40.50.1980 136 307 1.0E-42 T 05-07-2017 K08M4_RS17400 97322dbe2555c561a5aca6e757376574 311 SUPERFAMILY SSF53807 45 306 6.28E-50 T 05-07-2017 K08M4_RS01110 447c6e818dfd69116d33b9ef38431919 335 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 321 1.3E-125 T 05-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 K08M4_RS01110 447c6e818dfd69116d33b9ef38431919 335 PIRSF PIRSF004532 1 331 1.7E-132 T 05-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 K08M4_RS01110 447c6e818dfd69116d33b9ef38431919 335 Gene3D G3DSA:3.30.540.10 1 171 6.8E-65 T 05-07-2017 K08M4_RS01110 447c6e818dfd69116d33b9ef38431919 335 Gene3D G3DSA:3.30.540.10 172 329 1.4E-45 T 05-07-2017 K08M4_RS01110 447c6e818dfd69116d33b9ef38431919 335 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 331 4.1E-167 T 05-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 K08M4_RS01110 447c6e818dfd69116d33b9ef38431919 335 SUPERFAMILY SSF56655 1 324 3.54E-104 T 05-07-2017 K08M4_RS09930 040af5d24d4c709df9ff5774c69d2e3b 164 PIRSF PIRSF001467 1 163 1.3E-24 T 05-07-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 K08M4_RS09930 040af5d24d4c709df9ff5774c69d2e3b 164 Gene3D G3DSA:2.40.100.10 2 162 6.6E-50 T 05-07-2017 IPR029000 Cyclophilin-like domain K08M4_RS09930 040af5d24d4c709df9ff5774c69d2e3b 164 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 36 53 - T 05-07-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 K08M4_RS09930 040af5d24d4c709df9ff5774c69d2e3b 164 SUPERFAMILY SSF50891 2 162 4.53E-55 T 05-07-2017 IPR029000 Cyclophilin-like domain K08M4_RS09930 040af5d24d4c709df9ff5774c69d2e3b 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 118 133 1.3E-9 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS09930 040af5d24d4c709df9ff5774c69d2e3b 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 41 53 1.3E-9 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS09930 040af5d24d4c709df9ff5774c69d2e3b 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 15 30 1.3E-9 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS09930 040af5d24d4c709df9ff5774c69d2e3b 164 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 2 161 1.7E-45 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 SUPERFAMILY SSF82693 42 126 6.63E-18 T 05-07-2017 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 4.0E-24 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 4.0E-24 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 4.0E-24 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 PRINTS PR00702 Acriflavin resistance protein family signature 547 564 4.0E-24 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 4.0E-24 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 4.0E-24 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 4.0E-24 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 Pfam PF00873 AcrB/AcrD/AcrF family 12 1019 3.9E-150 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 SUPERFAMILY SSF82714 714 801 8.89E-8 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 Gene3D G3DSA:3.30.70.1430 42 128 2.0E-20 T 05-07-2017 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 SUPERFAMILY SSF82866 297 489 1.83E-38 T 05-07-2017 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 Gene3D G3DSA:1.20.1640.10 298 494 5.1E-46 T 05-07-2017 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 SUPERFAMILY SSF82714 184 266 1.57E-6 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 Gene3D G3DSA:1.10.3850.10 808 1021 1.6E-40 T 05-07-2017 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 Gene3D G3DSA:3.30.2090.10 183 267 1.7E-6 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 SUPERFAMILY SSF82693 270 325 3.4E-8 T 05-07-2017 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 SUPERFAMILY SSF82693 147 182 3.4E-8 T 05-07-2017 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 SUPERFAMILY SSF82693 561 658 2.54E-5 T 05-07-2017 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 SUPERFAMILY SSF82866 801 1023 5.1E-39 T 05-07-2017 K08M4_RS09975 0a247dcdd8c74e590cb3a5c711aa8735 1032 Gene3D G3DSA:3.30.2090.10 713 802 1.1E-7 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS14065 f67497c742d802c587031e5a793c19b3 280 SUPERFAMILY SSF56784 1 264 5.26E-59 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS14065 f67497c742d802c587031e5a793c19b3 280 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 05-07-2017 IPR000150 Cof protein GO:0016787 K08M4_RS14065 f67497c742d802c587031e5a793c19b3 280 Gene3D G3DSA:3.40.50.1000 178 268 3.6E-45 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS14065 f67497c742d802c587031e5a793c19b3 280 Gene3D G3DSA:3.40.50.1000 1 73 3.6E-45 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS14065 f67497c742d802c587031e5a793c19b3 280 ProSitePatterns PS01229 Hypothetical cof family signature 2. 217 239 - T 05-07-2017 K08M4_RS14065 f67497c742d802c587031e5a793c19b3 280 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 263 2.4E-54 T 05-07-2017 IPR000150 Cof protein GO:0016787 K08M4_RS14065 f67497c742d802c587031e5a793c19b3 280 Gene3D G3DSA:3.30.1240.10 84 177 5.2E-6 T 05-07-2017 K08M4_RS14065 f67497c742d802c587031e5a793c19b3 280 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 263 5.3E-58 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS14065 f67497c742d802c587031e5a793c19b3 280 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 236 2.4E-22 T 05-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 K08M4_RS16915 0ca046ec9435c44b040d631f751c4df6 234 SMART SM00345 6 65 3.5E-16 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS16915 0ca046ec9435c44b040d631f751c4df6 234 SUPERFAMILY SSF46785 3 69 3.77E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16915 0ca046ec9435c44b040d631f751c4df6 234 Gene3D G3DSA:1.10.10.10 3 61 8.8E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16915 0ca046ec9435c44b040d631f751c4df6 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 65 5.0E-18 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS16915 0ca046ec9435c44b040d631f751c4df6 234 Pfam PF07702 UTRA domain 86 224 1.3E-36 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 K08M4_RS16915 0ca046ec9435c44b040d631f751c4df6 234 TIGRFAM TIGR03337 phnR: phosphonate utilization transcriptional regulator PhnR 2 230 2.9E-112 T 05-07-2017 IPR017722 Phosphonate utilization transcriptional regulator PhnR K08M4_RS16915 0ca046ec9435c44b040d631f751c4df6 234 Gene3D G3DSA:3.40.1410.10 62 228 8.1E-43 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain K08M4_RS16915 0ca046ec9435c44b040d631f751c4df6 234 SMART SM00866 86 225 2.1E-31 T 05-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 K08M4_RS16915 0ca046ec9435c44b040d631f751c4df6 234 SUPERFAMILY SSF64288 53 229 1.57E-40 T 05-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain K08M4_RS16915 0ca046ec9435c44b040d631f751c4df6 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 25 39 3.0E-9 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS16915 0ca046ec9435c44b040d631f751c4df6 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 55 3.0E-9 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS11065 7511700a0a555040386521b5d56c81c3 346 SUPERFAMILY SSF55326 8 171 4.19E-53 T 05-07-2017 K08M4_RS11065 7511700a0a555040386521b5d56c81c3 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 8 335 2.0E-149 T 05-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 K08M4_RS11065 7511700a0a555040386521b5d56c81c3 346 SUPERFAMILY SSF56042 172 342 9.72E-63 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain K08M4_RS11065 7511700a0a555040386521b5d56c81c3 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 8 345 47.541 T 05-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 K08M4_RS11065 7511700a0a555040386521b5d56c81c3 346 Gene3D G3DSA:3.30.1330.10 23 171 1.3E-63 T 05-07-2017 IPR016188 PurM-like, N-terminal domain K08M4_RS11065 7511700a0a555040386521b5d56c81c3 346 Gene3D G3DSA:3.90.650.10 173 344 1.3E-68 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain K08M4_RS11065 7511700a0a555040386521b5d56c81c3 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 178 340 1.3E-40 T 05-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain K08M4_RS11065 7511700a0a555040386521b5d56c81c3 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 59 165 3.6E-15 T 05-07-2017 IPR016188 PurM-like, N-terminal domain K08M4_RS10075 bd0aea24d822603444ec56b078895d42 150 Gene3D G3DSA:2.40.40.10 49 141 1.4E-11 T 05-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain K08M4_RS10075 bd0aea24d822603444ec56b078895d42 150 Pfam PF03330 Lytic transglycolase 49 137 4.1E-29 T 05-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain K08M4_RS10075 bd0aea24d822603444ec56b078895d42 150 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 50 144 1.2E-41 T 05-07-2017 IPR012997 Rare lipoprotein A K08M4_RS10075 bd0aea24d822603444ec56b078895d42 150 SUPERFAMILY SSF50685 51 141 8.02E-17 T 05-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain K08M4_RS10500 dddd0e15d3e14f61ebca397d1b9e0ce7 277 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 277 45.332 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 K08M4_RS10500 dddd0e15d3e14f61ebca397d1b9e0ce7 277 Gene3D G3DSA:3.30.70.260 3 70 3.7E-11 T 05-07-2017 K08M4_RS10500 dddd0e15d3e14f61ebca397d1b9e0ce7 277 SUPERFAMILY SSF55021 4 66 9.99E-9 T 05-07-2017 K08M4_RS10500 dddd0e15d3e14f61ebca397d1b9e0ce7 277 SUPERFAMILY SSF53328 82 276 1.13E-59 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 K08M4_RS10500 dddd0e15d3e14f61ebca397d1b9e0ce7 277 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 229 251 6.4E-64 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 K08M4_RS10500 dddd0e15d3e14f61ebca397d1b9e0ce7 277 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 6 32 6.4E-64 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 K08M4_RS10500 dddd0e15d3e14f61ebca397d1b9e0ce7 277 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 83 105 6.4E-64 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 K08M4_RS10500 dddd0e15d3e14f61ebca397d1b9e0ce7 277 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 251 276 6.4E-64 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 K08M4_RS10500 dddd0e15d3e14f61ebca397d1b9e0ce7 277 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 105 132 6.4E-64 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 K08M4_RS10500 dddd0e15d3e14f61ebca397d1b9e0ce7 277 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 38 50 6.4E-64 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 K08M4_RS10500 dddd0e15d3e14f61ebca397d1b9e0ce7 277 Pfam PF01842 ACT domain 5 66 9.0E-8 T 05-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 K08M4_RS10500 dddd0e15d3e14f61ebca397d1b9e0ce7 277 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 5 277 1.9E-123 T 05-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 K08M4_RS10500 dddd0e15d3e14f61ebca397d1b9e0ce7 277 Pfam PF00551 Formyl transferase 82 259 1.6E-48 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 K08M4_RS10500 dddd0e15d3e14f61ebca397d1b9e0ce7 277 Gene3D G3DSA:3.40.50.170 82 274 1.4E-55 T 05-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 K08M4_RS10500 dddd0e15d3e14f61ebca397d1b9e0ce7 277 PIRSF PIRSF036480 1 277 6.7E-113 T 05-07-2017 K08M4_RS14140 246818ea77a8726457ca240da8ab7aaf 692 Gene3D G3DSA:3.40.50.300 255 452 1.7E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14140 246818ea77a8726457ca240da8ab7aaf 692 SMART SM00490 504 588 1.5E-21 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS14140 246818ea77a8726457ca240da8ab7aaf 692 Pfam PF00270 DEAD/DEAH box helicase 289 432 5.3E-19 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS14140 246818ea77a8726457ca240da8ab7aaf 692 SUPERFAMILY SSF52540 507 652 5.21E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14140 246818ea77a8726457ca240da8ab7aaf 692 SUPERFAMILY SSF52540 291 341 5.21E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14140 246818ea77a8726457ca240da8ab7aaf 692 SUPERFAMILY SSF52540 214 452 1.13E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14140 246818ea77a8726457ca240da8ab7aaf 692 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 28 663 1.1E-235 T 05-07-2017 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 K08M4_RS14140 246818ea77a8726457ca240da8ab7aaf 692 Gene3D G3DSA:1.10.150.20 2 36 9.8E-6 T 05-07-2017 K08M4_RS14140 246818ea77a8726457ca240da8ab7aaf 692 Pfam PF00271 Helicase conserved C-terminal domain 479 587 8.1E-19 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS14140 246818ea77a8726457ca240da8ab7aaf 692 SUPERFAMILY SSF50249 8 173 1.88E-40 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS14140 246818ea77a8726457ca240da8ab7aaf 692 SMART SM00487 264 458 1.5E-28 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS14140 246818ea77a8726457ca240da8ab7aaf 692 Gene3D G3DSA:3.40.50.300 453 637 3.3E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14140 246818ea77a8726457ca240da8ab7aaf 692 Gene3D G3DSA:2.40.50.140 46 140 2.5E-31 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS14140 246818ea77a8726457ca240da8ab7aaf 692 Pfam PF17191 RecG wedge domain 13 171 1.3E-21 T 05-07-2017 IPR033454 RecG, wedge domain K08M4_RS13925 aa3db372bef46ebffcd30d0809864c0f 364 Gene3D G3DSA:3.40.50.720 1 191 5.8E-65 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13925 aa3db372bef46ebffcd30d0809864c0f 364 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 339 7.0E-158 T 05-07-2017 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 K08M4_RS13925 aa3db372bef46ebffcd30d0809864c0f 364 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 326 7.5E-99 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13925 aa3db372bef46ebffcd30d0809864c0f 364 Gene3D G3DSA:3.90.25.10 192 338 4.9E-56 T 05-07-2017 K08M4_RS13925 aa3db372bef46ebffcd30d0809864c0f 364 SUPERFAMILY SSF51735 1 337 1.84E-93 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS05775 6eb87abf404cf42e09240a04b0f5c556 401 Gene3D G3DSA:3.20.20.450 142 387 2.2E-63 T 05-07-2017 IPR001633 EAL domain K08M4_RS05775 6eb87abf404cf42e09240a04b0f5c556 401 SMART SM00052 136 379 5.1E-59 T 05-07-2017 IPR001633 EAL domain K08M4_RS05775 6eb87abf404cf42e09240a04b0f5c556 401 SUPERFAMILY SSF141868 142 387 3.27E-61 T 05-07-2017 IPR001633 EAL domain K08M4_RS05775 6eb87abf404cf42e09240a04b0f5c556 401 Gene3D G3DSA:3.40.50.2300 2 135 3.2E-21 T 05-07-2017 K08M4_RS05775 6eb87abf404cf42e09240a04b0f5c556 401 SUPERFAMILY SSF52172 4 122 1.85E-20 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS05775 6eb87abf404cf42e09240a04b0f5c556 401 SMART SM00448 3 120 1.4E-14 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS05775 6eb87abf404cf42e09240a04b0f5c556 401 Pfam PF00072 Response regulator receiver domain 5 120 5.4E-22 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS05775 6eb87abf404cf42e09240a04b0f5c556 401 Pfam PF00563 EAL domain 142 374 2.6E-48 T 05-07-2017 IPR001633 EAL domain K08M4_RS09320 b99145ee8fac7d899bb78e6913eef637 344 Gene3D G3DSA:2.40.50.100 62 91 6.0E-12 T 05-07-2017 K08M4_RS09320 b99145ee8fac7d899bb78e6913eef637 344 Gene3D G3DSA:2.40.50.100 152 184 6.0E-12 T 05-07-2017 K08M4_RS09320 b99145ee8fac7d899bb78e6913eef637 344 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 34 338 1.1E-83 T 05-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 K08M4_RS09320 b99145ee8fac7d899bb78e6913eef637 344 SUPERFAMILY SSF111369 47 265 1.26E-29 T 05-07-2017 K08M4_RS09320 b99145ee8fac7d899bb78e6913eef637 344 Pfam PF13533 Biotin-lipoyl like 61 105 2.3E-10 T 05-07-2017 K08M4_RS09320 b99145ee8fac7d899bb78e6913eef637 344 Pfam PF13437 HlyD family secretion protein 154 250 9.5E-9 T 05-07-2017 K08M4_RS06485 96e9060677e118c52966875fea09f499 391 SUPERFAMILY SSF51246 317 389 1.73E-17 T 05-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 K08M4_RS06485 96e9060677e118c52966875fea09f499 391 Pfam PF01370 NAD dependent epimerase/dehydratase family 17 80 1.2E-4 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 K08M4_RS06485 96e9060677e118c52966875fea09f499 391 SUPERFAMILY SSF56059 111 313 8.66E-56 T 05-07-2017 K08M4_RS06485 96e9060677e118c52966875fea09f499 391 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 12 389 5.0E-189 T 05-07-2017 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 K08M4_RS06485 96e9060677e118c52966875fea09f499 391 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 6 390 51.453 T 05-07-2017 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 K08M4_RS06485 96e9060677e118c52966875fea09f499 391 SUPERFAMILY SSF52440 2 110 1.29E-35 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS06485 96e9060677e118c52966875fea09f499 391 Gene3D G3DSA:3.30.470.20 197 387 7.6E-68 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS06485 96e9060677e118c52966875fea09f499 391 Gene3D G3DSA:3.30.1490.20 121 196 2.8E-25 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 K08M4_RS06485 96e9060677e118c52966875fea09f499 391 Pfam PF02222 ATP-grasp domain 121 292 1.8E-56 T 05-07-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type K08M4_RS06485 96e9060677e118c52966875fea09f499 391 Gene3D G3DSA:3.40.50.20 3 118 2.2E-40 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS02495 ab8b036bec567bdcc2ac3bc37baf56d6 741 Pfam PF04607 Region found in RelA / SpoT proteins 250 359 7.1E-36 T 05-07-2017 IPR007685 RelA/SpoT GO:0015969 K08M4_RS02495 ab8b036bec567bdcc2ac3bc37baf56d6 741 Gene3D G3DSA:3.30.70.260 664 738 3.7E-16 T 05-07-2017 K08M4_RS02495 ab8b036bec567bdcc2ac3bc37baf56d6 741 SUPERFAMILY SSF109604 32 205 1.16E-40 T 05-07-2017 K08M4_RS02495 ab8b036bec567bdcc2ac3bc37baf56d6 741 Gene3D G3DSA:3.30.460.10 193 339 1.0E-48 T 05-07-2017 K08M4_RS02495 ab8b036bec567bdcc2ac3bc37baf56d6 741 Pfam PF13328 HD domain 51 190 1.4E-34 T 05-07-2017 IPR003607 HD/PDEase domain K08M4_RS02495 ab8b036bec567bdcc2ac3bc37baf56d6 741 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 64 739 1.7E-179 T 05-07-2017 IPR004811 RelA/SpoT family GO:0015969 K08M4_RS02495 ab8b036bec567bdcc2ac3bc37baf56d6 741 SUPERFAMILY SSF81301 195 408 1.01E-60 T 05-07-2017 K08M4_RS02495 ab8b036bec567bdcc2ac3bc37baf56d6 741 SMART SM00954 250 360 3.3E-62 T 05-07-2017 IPR007685 RelA/SpoT GO:0015969 K08M4_RS02495 ab8b036bec567bdcc2ac3bc37baf56d6 741 Pfam PF13291 ACT domain 663 739 1.9E-14 T 05-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 K08M4_RS02495 ab8b036bec567bdcc2ac3bc37baf56d6 741 Gene3D G3DSA:3.10.20.30 404 465 3.6E-23 T 05-07-2017 IPR012675 Beta-grasp domain K08M4_RS02495 ab8b036bec567bdcc2ac3bc37baf56d6 741 SUPERFAMILY SSF55021 664 739 1.74E-9 T 05-07-2017 K08M4_RS02495 ab8b036bec567bdcc2ac3bc37baf56d6 741 Pfam PF02824 TGS domain 404 463 1.8E-20 T 05-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 K08M4_RS02495 ab8b036bec567bdcc2ac3bc37baf56d6 741 SUPERFAMILY SSF81271 397 463 1.68E-19 T 05-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 K08M4_RS01035 ce454ed4b3447fb8209d163efd099f19 437 PIRSF PIRSF004539 1 437 7.7E-181 T 05-07-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 K08M4_RS01035 ce454ed4b3447fb8209d163efd099f19 437 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 5 436 3.0E-181 T 05-07-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 K08M4_RS01035 ce454ed4b3447fb8209d163efd099f19 437 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 5 369 6.7E-154 T 05-07-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 K08M4_RS11840 f5c05fd9e8220d1e3d8e64c86ac7691a 422 PIRSF PIRSF001549 2 421 2.9E-124 T 05-07-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 K08M4_RS11840 f5c05fd9e8220d1e3d8e64c86ac7691a 422 Gene3D G3DSA:3.30.930.10 4 185 1.6E-98 T 05-07-2017 K08M4_RS11840 f5c05fd9e8220d1e3d8e64c86ac7691a 422 Gene3D G3DSA:3.30.930.10 221 321 1.6E-98 T 05-07-2017 K08M4_RS11840 f5c05fd9e8220d1e3d8e64c86ac7691a 422 Gene3D G3DSA:3.40.50.800 327 420 5.7E-31 T 05-07-2017 IPR004154 Anticodon-binding K08M4_RS11840 f5c05fd9e8220d1e3d8e64c86ac7691a 422 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 420 33.486 T 05-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 K08M4_RS11840 f5c05fd9e8220d1e3d8e64c86ac7691a 422 SUPERFAMILY SSF52954 327 421 9.0E-26 T 05-07-2017 IPR004154 Anticodon-binding K08M4_RS11840 f5c05fd9e8220d1e3d8e64c86ac7691a 422 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 410 5.8E-158 T 05-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 K08M4_RS11840 f5c05fd9e8220d1e3d8e64c86ac7691a 422 Pfam PF13393 Histidyl-tRNA synthetase 10 312 2.3E-45 T 05-07-2017 K08M4_RS11840 f5c05fd9e8220d1e3d8e64c86ac7691a 422 SUPERFAMILY SSF55681 5 320 1.21E-102 T 05-07-2017 K08M4_RS11840 f5c05fd9e8220d1e3d8e64c86ac7691a 422 Pfam PF03129 Anticodon binding domain 343 420 4.4E-10 T 05-07-2017 IPR004154 Anticodon-binding K08M4_RS17935 8a3fb6234cae13063794c2bd65259351 551 Gene3D G3DSA:3.40.50.300 422 528 2.9E-4 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17935 8a3fb6234cae13063794c2bd65259351 551 Gene3D G3DSA:3.40.50.300 32 190 3.9E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17935 8a3fb6234cae13063794c2bd65259351 551 Pfam PF12592 Protein of unknown function (DUF3763) 481 533 4.1E-18 T 05-07-2017 IPR022547 ATPase, RavA, C-terminal GO:0016820 K08M4_RS17935 8a3fb6234cae13063794c2bd65259351 551 SUPERFAMILY SSF52540 17 278 7.36E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17935 8a3fb6234cae13063794c2bd65259351 551 SMART SM00382 45 162 1.3E-5 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS17935 8a3fb6234cae13063794c2bd65259351 551 Pfam PF07728 AAA domain (dynein-related subfamily) 48 178 1.4E-22 T 05-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 K08M4_RS20335 7a9c8cd65e15663cbb15bca33f86ceda 459 Gene3D G3DSA:3.40.50.300 3 205 7.6E-77 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20335 7a9c8cd65e15663cbb15bca33f86ceda 459 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 05-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site K08M4_RS20335 7a9c8cd65e15663cbb15bca33f86ceda 459 Gene3D G3DSA:3.40.50.300 206 370 7.2E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20335 7a9c8cd65e15663cbb15bca33f86ceda 459 SMART SM00490 257 338 1.2E-28 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS20335 7a9c8cd65e15663cbb15bca33f86ceda 459 SMART SM00487 23 220 1.7E-58 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS20335 7a9c8cd65e15663cbb15bca33f86ceda 459 SUPERFAMILY SSF52540 73 355 1.03E-71 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20335 7a9c8cd65e15663cbb15bca33f86ceda 459 Pfam PF03880 DbpA RNA binding domain 386 456 7.9E-21 T 05-07-2017 IPR005580 DbpA, RNA-binding domain K08M4_RS20335 7a9c8cd65e15663cbb15bca33f86ceda 459 Pfam PF00270 DEAD/DEAH box helicase 28 194 1.7E-46 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS20335 7a9c8cd65e15663cbb15bca33f86ceda 459 Pfam PF00271 Helicase conserved C-terminal domain 235 338 1.2E-26 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS15425 cdf2d7798204583250e5ff2f238403c3 690 Pfam PF14863 Alkyl sulfatase dimerisation 401 537 1.8E-50 T 05-07-2017 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 K08M4_RS15425 cdf2d7798204583250e5ff2f238403c3 690 SUPERFAMILY SSF55718 548 669 1.97E-28 T 05-07-2017 IPR003033 SCP2 sterol-binding domain K08M4_RS15425 cdf2d7798204583250e5ff2f238403c3 690 SMART SM00849 139 362 1.1E-19 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS15425 cdf2d7798204583250e5ff2f238403c3 690 Pfam PF00753 Metallo-beta-lactamase superfamily 136 362 2.5E-21 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS15425 cdf2d7798204583250e5ff2f238403c3 690 Gene3D G3DSA:3.30.1050.10 558 658 4.8E-8 T 05-07-2017 IPR003033 SCP2 sterol-binding domain K08M4_RS15425 cdf2d7798204583250e5ff2f238403c3 690 Gene3D G3DSA:3.60.15.10 266 392 1.6E-35 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS15425 cdf2d7798204583250e5ff2f238403c3 690 Gene3D G3DSA:3.60.15.10 129 224 1.6E-35 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS15425 cdf2d7798204583250e5ff2f238403c3 690 Pfam PF14864 Alkyl sulfatase C-terminal 547 669 1.2E-32 T 05-07-2017 IPR029229 Alkyl sulfatase, C-terminal K08M4_RS15425 cdf2d7798204583250e5ff2f238403c3 690 SUPERFAMILY SSF56281 40 540 3.22E-122 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS01880 cc34bed14b0cb34a8b430d92c360bdef 241 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 50 180 2.1E-42 T 05-07-2017 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 K08M4_RS01880 cc34bed14b0cb34a8b430d92c360bdef 241 SUPERFAMILY SSF69593 7 237 1.11E-56 T 05-07-2017 K08M4_RS01880 cc34bed14b0cb34a8b430d92c360bdef 241 Pfam PF01553 Acyltransferase 58 180 9.1E-31 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 K08M4_RS01880 cc34bed14b0cb34a8b430d92c360bdef 241 Gene3D G3DSA:3.40.1130.10 45 231 6.0E-18 T 05-07-2017 K08M4_RS01880 cc34bed14b0cb34a8b430d92c360bdef 241 SMART SM00563 67 182 5.4E-39 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 K08M4_RS11165 5451e5e3f1d12b5b5caffb5b34d214b1 262 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 180 261 5.0E-27 T 05-07-2017 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 K08M4_RS11165 5451e5e3f1d12b5b5caffb5b34d214b1 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 20 52 1.8E-8 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS11165 5451e5e3f1d12b5b5caffb5b34d214b1 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 143 4.6E-7 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS11165 5451e5e3f1d12b5b5caffb5b34d214b1 262 PIRSF PIRSF000456 4 262 1.3E-95 T 05-07-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 K08M4_RS11165 5451e5e3f1d12b5b5caffb5b34d214b1 262 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 8 260 7.4E-96 T 05-07-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 K08M4_RS11165 5451e5e3f1d12b5b5caffb5b34d214b1 262 SUPERFAMILY SSF51161 1 262 1.9E-75 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS11165 5451e5e3f1d12b5b5caffb5b34d214b1 262 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 5 262 42.636 T 05-07-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 K08M4_RS11165 5451e5e3f1d12b5b5caffb5b34d214b1 262 Gene3D G3DSA:1.20.1180.10 197 262 1.2E-23 T 05-07-2017 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 K08M4_RS11165 5451e5e3f1d12b5b5caffb5b34d214b1 262 Gene3D G3DSA:2.160.10.10 3 194 3.2E-45 T 05-07-2017 K08M4_RS07605 59a0a454d17d3f49259af1ff16415377 282 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 140 277 6.3E-16 T 05-07-2017 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 K08M4_RS20955 06f011870359e7d344869c1a8c446f92 659 Pfam PF08376 Nitrate and nitrite sensing 56 291 3.5E-51 T 05-07-2017 IPR013587 Nitrate/nitrite sensing protein K08M4_RS20955 06f011870359e7d344869c1a8c446f92 659 Gene3D G3DSA:1.10.287.950 411 627 2.3E-56 T 05-07-2017 K08M4_RS20955 06f011870359e7d344869c1a8c446f92 659 SMART SM00283 397 658 1.1E-73 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS20955 06f011870359e7d344869c1a8c446f92 659 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 471 657 3.4E-46 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS20955 06f011870359e7d344869c1a8c446f92 659 SMART SM00304 329 382 9.5E-4 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS20955 06f011870359e7d344869c1a8c446f92 659 SUPERFAMILY SSF58104 350 658 5.89E-74 T 05-07-2017 K08M4_RS14680 08c13ea33977c4628644298c826e0987 142 Pfam PF13551 Winged helix-turn helix 4 63 9.7E-13 T 05-07-2017 K08M4_RS14680 08c13ea33977c4628644298c826e0987 142 Gene3D G3DSA:1.10.10.10 5 57 4.6E-6 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS14680 08c13ea33977c4628644298c826e0987 142 Pfam PF13592 Winged helix-turn helix 79 136 1.5E-13 T 05-07-2017 IPR025959 Winged helix-turn helix domain K08M4_RS14680 08c13ea33977c4628644298c826e0987 142 SUPERFAMILY SSF46689 2 112 1.34E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00395 b62216432a09a1cfc09d3064a6ae5ec0 242 Gene3D G3DSA:3.40.50.10090 2 114 2.6E-8 T 05-07-2017 K08M4_RS00395 b62216432a09a1cfc09d3064a6ae5ec0 242 Gene3D G3DSA:3.40.50.10090 119 224 6.1E-6 T 05-07-2017 K08M4_RS00395 b62216432a09a1cfc09d3064a6ae5ec0 242 SUPERFAMILY SSF69618 1 240 1.7E-46 T 05-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS00395 b62216432a09a1cfc09d3064a6ae5ec0 242 Pfam PF02602 Uroporphyrinogen-III synthase HemD 15 233 1.5E-30 T 05-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS11420 1e2ac948f0e2df9cba2fc1f3fe43f46c 454 Gene3D G3DSA:3.40.50.450 123 450 5.7E-126 T 05-07-2017 K08M4_RS11420 1e2ac948f0e2df9cba2fc1f3fe43f46c 454 Pfam PF03641 Possible lysine decarboxylase 187 326 7.0E-35 T 05-07-2017 IPR031100 LOG family K08M4_RS11420 1e2ac948f0e2df9cba2fc1f3fe43f46c 454 SUPERFAMILY SSF102405 119 327 4.43E-41 T 05-07-2017 K08M4_RS11420 1e2ac948f0e2df9cba2fc1f3fe43f46c 454 Pfam PF14793 Domain of unknown function (DUF4478) 4 109 1.9E-50 T 05-07-2017 IPR027820 Domain of unknown function DUF4478 K08M4_RS11420 1e2ac948f0e2df9cba2fc1f3fe43f46c 454 Gene3D G3DSA:3.30.1850.10 1 113 5.4E-57 T 05-07-2017 IPR027820 Domain of unknown function DUF4478 K08M4_RS11420 1e2ac948f0e2df9cba2fc1f3fe43f46c 454 Pfam PF11892 Domain of unknown function (DUF3412) 330 451 8.3E-58 T 05-07-2017 IPR021826 Protein of unknown function DUF3412 K08M4_RS17080 726f65bbdf1e3882cddf518475a6fdd1 404 Pfam PF02687 FtsX-like permease family 281 396 2.0E-17 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 K08M4_RS17080 726f65bbdf1e3882cddf518475a6fdd1 404 Pfam PF12704 MacB-like periplasmic core domain 19 226 1.2E-24 T 05-07-2017 IPR025857 MacB-like periplasmic core domain K08M4_RS18565 a8a3bc0f6d1cf1e63332afb6c6f1bccf 331 SUPERFAMILY SSF52440 4 115 2.21E-27 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS18565 a8a3bc0f6d1cf1e63332afb6c6f1bccf 331 Pfam PF07478 D-ala D-ala ligase C-terminus 126 325 2.4E-54 T 05-07-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS18565 a8a3bc0f6d1cf1e63332afb6c6f1bccf 331 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 83 94 - T 05-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS18565 a8a3bc0f6d1cf1e63332afb6c6f1bccf 331 Gene3D G3DSA:3.40.50.20 4 103 7.7E-22 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS18565 a8a3bc0f6d1cf1e63332afb6c6f1bccf 331 PIRSF PIRSF039102 1 331 1.8E-77 T 05-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS18565 a8a3bc0f6d1cf1e63332afb6c6f1bccf 331 Pfam PF01820 D-ala D-ala ligase N-terminus 5 106 3.5E-21 T 05-07-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS18565 a8a3bc0f6d1cf1e63332afb6c6f1bccf 331 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 328 1.5E-97 T 05-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS18565 a8a3bc0f6d1cf1e63332afb6c6f1bccf 331 SUPERFAMILY SSF56059 116 326 4.32E-44 T 05-07-2017 K08M4_RS18565 a8a3bc0f6d1cf1e63332afb6c6f1bccf 331 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 272 300 - T 05-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS18565 a8a3bc0f6d1cf1e63332afb6c6f1bccf 331 Gene3D G3DSA:3.30.470.20 201 330 7.5E-39 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS18565 a8a3bc0f6d1cf1e63332afb6c6f1bccf 331 Gene3D G3DSA:3.30.1490.20 133 198 2.1E-17 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 K08M4_RS18565 a8a3bc0f6d1cf1e63332afb6c6f1bccf 331 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 330 32.466 T 05-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS00040 5a36450e9023ee276b0146580cd3d34e 309 Gene3D G3DSA:1.20.58.180 216 299 1.0E-36 T 05-07-2017 K08M4_RS00040 5a36450e9023ee276b0146580cd3d34e 309 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 7 294 61.409 T 05-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS00040 5a36450e9023ee276b0146580cd3d34e 309 SUPERFAMILY SSF55681 8 293 1.59E-132 T 05-07-2017 K08M4_RS00040 5a36450e9023ee276b0146580cd3d34e 309 Gene3D G3DSA:3.30.930.10 4 215 5.5E-104 T 05-07-2017 K08M4_RS00040 5a36450e9023ee276b0146580cd3d34e 309 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 139 159 3.8E-70 T 05-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS00040 5a36450e9023ee276b0146580cd3d34e 309 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 113 137 3.8E-70 T 05-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS00040 5a36450e9023ee276b0146580cd3d34e 309 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 61 76 3.8E-70 T 05-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS00040 5a36450e9023ee276b0146580cd3d34e 309 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 162 177 3.8E-70 T 05-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS00040 5a36450e9023ee276b0146580cd3d34e 309 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 82 102 3.8E-70 T 05-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS00040 5a36450e9023ee276b0146580cd3d34e 309 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 254 270 3.8E-70 T 05-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS00040 5a36450e9023ee276b0146580cd3d34e 309 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 9 292 3.0E-148 T 05-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS00040 5a36450e9023ee276b0146580cd3d34e 309 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 7 301 5.4E-169 T 05-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 K08M4_RS12265 ce07f82624171c9a7236ed3dfd891bae 296 Gene3D G3DSA:3.40.190.10 121 227 2.5E-6 T 05-07-2017 K08M4_RS12265 ce07f82624171c9a7236ed3dfd891bae 296 SUPERFAMILY SSF53850 90 288 1.13E-22 T 05-07-2017 K08M4_RS12265 ce07f82624171c9a7236ed3dfd891bae 296 SUPERFAMILY SSF46785 2 85 1.72E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS12265 ce07f82624171c9a7236ed3dfd891bae 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 6.9E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS12265 ce07f82624171c9a7236ed3dfd891bae 296 Pfam PF03466 LysR substrate binding domain 97 288 5.8E-11 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS12265 ce07f82624171c9a7236ed3dfd891bae 296 Gene3D G3DSA:1.10.10.10 3 81 9.3E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS13190 d3520a571b5bfe9f7b695db4d77ebf11 480 SUPERFAMILY SSF53067 47 154 5.7E-9 T 05-07-2017 K08M4_RS13190 d3520a571b5bfe9f7b695db4d77ebf11 480 PIRSF PIRSF028153 1 480 3.9E-193 T 05-07-2017 IPR016871 MSHA biogenesis protein, MshI K08M4_RS17415 900ed4fe3199867806da7a8a3dc2ce6d 387 Gene3D G3DSA:2.40.160.60 23 386 1.6E-79 T 05-07-2017 K08M4_RS17415 900ed4fe3199867806da7a8a3dc2ce6d 387 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 177 359 6.7E-36 T 05-07-2017 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) K08M4_RS17415 900ed4fe3199867806da7a8a3dc2ce6d 387 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 16 173 5.1E-23 T 05-07-2017 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) K08M4_RS17415 900ed4fe3199867806da7a8a3dc2ce6d 387 SUPERFAMILY SSF56935 23 386 1.33E-67 T 05-07-2017 K08M4_RS09410 b549ca69c7e1ab43f9a414df1c69c88f 280 Gene3D G3DSA:1.20.1080.10 29 279 6.9E-87 T 05-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 K08M4_RS09410 b549ca69c7e1ab43f9a414df1c69c88f 280 Pfam PF01226 Formate/nitrite transporter 13 275 5.3E-76 T 05-07-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 K08M4_RS09410 b549ca69c7e1ab43f9a414df1c69c88f 280 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 82 91 - T 05-07-2017 IPR024002 Formate/nitrite transporter, conserved site K08M4_RS09410 b549ca69c7e1ab43f9a414df1c69c88f 280 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 25 279 1.1E-78 T 05-07-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 K08M4_RS09410 b549ca69c7e1ab43f9a414df1c69c88f 280 TIGRFAM TIGR04060 formate_focA: formate transporter FocA 13 278 6.7E-115 T 05-07-2017 IPR023999 Formate transporter FocA, putative GO:0015499|GO:0015724|GO:0016021 K08M4_RS16030 7fdb70ba392810add634f6fa03d7a42e 638 Gene3D G3DSA:1.10.287.950 390 605 1.7E-58 T 05-07-2017 K08M4_RS16030 7fdb70ba392810add634f6fa03d7a42e 638 Gene3D G3DSA:3.30.450.20 176 282 2.3E-16 T 05-07-2017 K08M4_RS16030 7fdb70ba392810add634f6fa03d7a42e 638 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 431 636 4.6E-51 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS16030 7fdb70ba392810add634f6fa03d7a42e 638 SUPERFAMILY SSF58104 329 638 4.97E-78 T 05-07-2017 K08M4_RS16030 7fdb70ba392810add634f6fa03d7a42e 638 SMART SM00283 376 637 8.0E-87 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS16030 7fdb70ba392810add634f6fa03d7a42e 638 Pfam PF00672 HAMP domain 288 357 1.0E-12 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS16030 7fdb70ba392810add634f6fa03d7a42e 638 SMART SM00304 307 361 2.4E-10 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS16030 7fdb70ba392810add634f6fa03d7a42e 638 SMART SM00304 396 463 68.0 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 Pfam PF13365 Trypsin-like peptidase domain 88 224 1.4E-30 T 05-07-2017 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 Gene3D G3DSA:2.30.42.10 384 450 1.0E-16 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 Gene3D G3DSA:2.30.42.10 266 360 1.9E-30 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 39 449 1.7E-161 T 05-07-2017 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 Gene3D G3DSA:2.40.10.10 37 151 4.8E-35 T 05-07-2017 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 SUPERFAMILY SSF50156 379 450 2.63E-14 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 Pfam PF13180 PDZ domain 264 354 3.9E-17 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 369 440 7.8E-9 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 PRINTS PR00834 HtrA/DegQ protease family signature 217 234 2.7E-57 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 PRINTS PR00834 HtrA/DegQ protease family signature 195 212 2.7E-57 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 PRINTS PR00834 HtrA/DegQ protease family signature 119 139 2.7E-57 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 PRINTS PR00834 HtrA/DegQ protease family signature 160 184 2.7E-57 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 PRINTS PR00834 HtrA/DegQ protease family signature 303 315 2.7E-57 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 PRINTS PR00834 HtrA/DegQ protease family signature 98 110 2.7E-57 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 Gene3D G3DSA:2.40.10.10 152 265 3.3E-43 T 05-07-2017 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 SMART SM00228 370 443 1.7E-7 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 SMART SM00228 263 345 1.0E-16 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 SUPERFAMILY SSF50494 14 58 1.73E-64 T 05-07-2017 IPR009003 Peptidase S1, PA clan K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 SUPERFAMILY SSF50494 85 272 1.73E-64 T 05-07-2017 IPR009003 Peptidase S1, PA clan K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 SUPERFAMILY SSF50156 280 357 1.16E-24 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS12690 3588539296742c5f4857515ad1d829a7 451 SUPERFAMILY SSF50156 214 240 1.16E-24 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS10540 5c70808c0f73f6f53ab407f78fa0a514 296 Pfam PF01297 Zinc-uptake complex component A periplasmic 23 291 6.2E-55 T 05-07-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 K08M4_RS10540 5c70808c0f73f6f53ab407f78fa0a514 296 SUPERFAMILY SSF53807 19 295 3.29E-73 T 05-07-2017 K08M4_RS10540 5c70808c0f73f6f53ab407f78fa0a514 296 Gene3D G3DSA:3.40.50.1980 16 183 8.2E-42 T 05-07-2017 K08M4_RS10540 5c70808c0f73f6f53ab407f78fa0a514 296 PRINTS PR00690 Adhesin family signature 182 203 7.0E-9 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 K08M4_RS10540 5c70808c0f73f6f53ab407f78fa0a514 296 PRINTS PR00690 Adhesin family signature 235 253 7.0E-9 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 K08M4_RS10540 5c70808c0f73f6f53ab407f78fa0a514 296 PRINTS PR00690 Adhesin family signature 64 81 7.0E-9 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 K08M4_RS10540 5c70808c0f73f6f53ab407f78fa0a514 296 PRINTS PR00690 Adhesin family signature 51 64 7.0E-9 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 K08M4_RS10540 5c70808c0f73f6f53ab407f78fa0a514 296 Gene3D G3DSA:3.40.50.1980 184 294 3.7E-28 T 05-07-2017 K08M4_RS10540 5c70808c0f73f6f53ab407f78fa0a514 296 PRINTS PR00691 Adhesin B signature 64 83 7.0E-5 T 05-07-2017 IPR006129 Adhesin B GO:0007155 K08M4_RS10540 5c70808c0f73f6f53ab407f78fa0a514 296 PRINTS PR00691 Adhesin B signature 45 63 7.0E-5 T 05-07-2017 IPR006129 Adhesin B GO:0007155 K08M4_RS10540 5c70808c0f73f6f53ab407f78fa0a514 296 PRINTS PR00691 Adhesin B signature 126 145 7.0E-5 T 05-07-2017 IPR006129 Adhesin B GO:0007155 K08M4_RS14380 b99add20dcd79dadf28c0673849baa72 347 Pfam PF00490 Delta-aminolevulinic acid dehydratase 12 332 2.3E-141 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS14380 b99add20dcd79dadf28c0673849baa72 347 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 198 217 3.3E-57 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS14380 b99add20dcd79dadf28c0673849baa72 347 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 252 268 3.3E-57 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS14380 b99add20dcd79dadf28c0673849baa72 347 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 129 143 3.3E-57 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS14380 b99add20dcd79dadf28c0673849baa72 347 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 307 326 3.3E-57 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS14380 b99add20dcd79dadf28c0673849baa72 347 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 277 292 3.3E-57 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS14380 b99add20dcd79dadf28c0673849baa72 347 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 160 179 3.3E-57 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS14380 b99add20dcd79dadf28c0673849baa72 347 Gene3D G3DSA:3.20.20.70 7 336 1.1E-153 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS14380 b99add20dcd79dadf28c0673849baa72 347 PIRSF PIRSF001415 2 336 6.5E-152 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS14380 b99add20dcd79dadf28c0673849baa72 347 SMART SM01004 9 333 1.8E-242 T 05-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS14380 b99add20dcd79dadf28c0673849baa72 347 SUPERFAMILY SSF51569 7 335 2.64E-144 T 05-07-2017 K08M4_RS14380 b99add20dcd79dadf28c0673849baa72 347 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 252 264 - T 05-07-2017 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS12180 20b72c439f062b32706c32bc11a171fe 375 SUPERFAMILY SSF48179 241 366 9.07E-41 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 K08M4_RS12180 20b72c439f062b32706c32bc11a171fe 375 Gene3D G3DSA:1.20.59.10 4 83 2.1E-23 T 05-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 K08M4_RS12180 20b72c439f062b32706c32bc11a171fe 375 SMART SM00830 9 89 5.2E-29 T 05-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 K08M4_RS12180 20b72c439f062b32706c32bc11a171fe 375 Pfam PF01817 Chorismate mutase type II 9 87 1.4E-21 T 05-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 K08M4_RS12180 20b72c439f062b32706c32bc11a171fe 375 SUPERFAMILY SSF51735 91 240 1.18E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS12180 20b72c439f062b32706c32bc11a171fe 375 SUPERFAMILY SSF48600 4 88 2.75E-24 T 05-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 K08M4_RS12180 20b72c439f062b32706c32bc11a171fe 375 TIGRFAM TIGR01799 CM_T: chorismate mutase 5 87 1.0E-41 T 05-07-2017 IPR011277 Chorismate mutase, T-protein GO:0004106|GO:0005737|GO:0006571|GO:0055114 KEGG: 00400+5.4.99.5+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7303|MetaCyc: PWY-7626 K08M4_RS12180 20b72c439f062b32706c32bc11a171fe 375 Gene3D G3DSA:3.40.50.720 84 247 1.2E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS12180 20b72c439f062b32706c32bc11a171fe 375 Gene3D G3DSA:1.10.3660.10 249 373 1.0E-54 T 05-07-2017 K08M4_RS12180 20b72c439f062b32706c32bc11a171fe 375 PIRSF PIRSF001499 1 374 1.3E-179 T 05-07-2017 IPR008244 Bifunctional chorismate mutase/prephenate dehydrogenase T-protein GO:0004106|GO:0005737|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+5.4.99.5+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7303|MetaCyc: PWY-7626 K08M4_RS12180 20b72c439f062b32706c32bc11a171fe 375 Pfam PF02153 Prephenate dehydrogenase 138 344 3.5E-29 T 05-07-2017 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 K08M4_RS06420 6783a3c245e02f3df1f0b699fb3726f5 133 SUPERFAMILY SSF55021 70 130 3.05E-18 T 05-07-2017 K08M4_RS06420 6783a3c245e02f3df1f0b699fb3726f5 133 Pfam PF13840 ACT domain 72 128 6.9E-10 T 05-07-2017 IPR027795 GATS-like ACT domain K08M4_RS06420 6783a3c245e02f3df1f0b699fb3726f5 133 Pfam PF10000 ACT domain 3 70 7.4E-26 T 05-07-2017 IPR018717 Domain of unknown function DUF2241 K08M4_RS06420 6783a3c245e02f3df1f0b699fb3726f5 133 Gene3D G3DSA:3.30.2130.10 1 130 1.4E-53 T 05-07-2017 K08M4_RS06420 6783a3c245e02f3df1f0b699fb3726f5 133 SUPERFAMILY SSF55021 3 66 1.46E-18 T 05-07-2017 K08M4_RS06225 a2e529772a319b54c7907b0b01b443d7 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 2.2E-8 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS06225 a2e529772a319b54c7907b0b01b443d7 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 2.2E-8 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS06225 a2e529772a319b54c7907b0b01b443d7 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 78 7.5E-17 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS06225 a2e529772a319b54c7907b0b01b443d7 239 SUPERFAMILY SSF46785 11 82 2.02E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06225 a2e529772a319b54c7907b0b01b443d7 239 Gene3D G3DSA:1.20.120.530 106 235 1.6E-24 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS06225 a2e529772a319b54c7907b0b01b443d7 239 SUPERFAMILY SSF48008 107 235 4.45E-24 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS06225 a2e529772a319b54c7907b0b01b443d7 239 SMART SM00345 19 78 4.0E-16 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS06225 a2e529772a319b54c7907b0b01b443d7 239 SMART SM00895 107 230 6.2E-18 T 05-07-2017 IPR011711 GntR, C-terminal K08M4_RS06225 a2e529772a319b54c7907b0b01b443d7 239 Gene3D G3DSA:1.10.10.10 11 87 1.2E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06225 a2e529772a319b54c7907b0b01b443d7 239 Pfam PF07729 FCD domain 108 229 8.1E-21 T 05-07-2017 IPR011711 GntR, C-terminal K08M4_RS13520 133204e30d33ac7e3f17be34611dbe97 435 Gene3D G3DSA:3.40.50.300 197 362 2.0E-37 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13520 133204e30d33ac7e3f17be34611dbe97 435 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 221 239 3.1E-10 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS13520 133204e30d33ac7e3f17be34611dbe97 435 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 267 285 3.1E-10 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS13520 133204e30d33ac7e3f17be34611dbe97 435 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 3.1E-10 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS13520 133204e30d33ac7e3f17be34611dbe97 435 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 361 9.3E-156 T 05-07-2017 IPR016496 GTPase HflX GO:0005525 K08M4_RS13520 133204e30d33ac7e3f17be34611dbe97 435 Pfam PF01926 50S ribosome-binding GTPase 200 318 8.8E-21 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS13520 133204e30d33ac7e3f17be34611dbe97 435 SUPERFAMILY SSF54980 364 430 5.28E-18 T 05-07-2017 IPR009022 Elongation factor G, III-V domain K08M4_RS13520 133204e30d33ac7e3f17be34611dbe97 435 Pfam PF13167 GTP-binding GTPase N-terminal 25 112 7.1E-30 T 05-07-2017 IPR025121 GTPase HflX, N-terminal K08M4_RS13520 133204e30d33ac7e3f17be34611dbe97 435 Pfam PF16360 GTP-binding GTPase Middle Region 114 192 2.4E-28 T 05-07-2017 IPR032305 GTP-binding protein, middle domain K08M4_RS13520 133204e30d33ac7e3f17be34611dbe97 435 PIRSF PIRSF006809 3 422 4.2E-149 T 05-07-2017 IPR016496 GTPase HflX GO:0005525 K08M4_RS13520 133204e30d33ac7e3f17be34611dbe97 435 SUPERFAMILY SSF52540 198 379 4.21E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13520 133204e30d33ac7e3f17be34611dbe97 435 Hamap MF_00900 GTPase HflX [hflX]. 27 390 46.235 T 05-07-2017 IPR016496 GTPase HflX GO:0005525 K08M4_RS11645 ad93fc9900838c7b108ea97dc9fa5d3b 429 Pfam PF00571 CBS domain 278 328 5.5E-5 T 05-07-2017 IPR000644 CBS domain K08M4_RS11645 ad93fc9900838c7b108ea97dc9fa5d3b 429 SMART SM00116 280 328 0.18 T 05-07-2017 IPR000644 CBS domain K08M4_RS11645 ad93fc9900838c7b108ea97dc9fa5d3b 429 SMART SM00116 218 267 7.4 T 05-07-2017 IPR000644 CBS domain K08M4_RS11645 ad93fc9900838c7b108ea97dc9fa5d3b 429 Gene3D G3DSA:3.10.580.10 195 321 2.0E-20 T 05-07-2017 K08M4_RS11645 ad93fc9900838c7b108ea97dc9fa5d3b 429 SUPERFAMILY SSF54631 196 330 1.89E-27 T 05-07-2017 K08M4_RS11645 ad93fc9900838c7b108ea97dc9fa5d3b 429 SUPERFAMILY SSF56176 341 418 2.64E-17 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 K08M4_RS11645 ad93fc9900838c7b108ea97dc9fa5d3b 429 Gene3D G3DSA:3.30.465.10 322 419 9.3E-22 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 K08M4_RS11645 ad93fc9900838c7b108ea97dc9fa5d3b 429 Pfam PF03471 Transporter associated domain 341 419 9.8E-17 T 05-07-2017 IPR005170 Transporter-associated domain K08M4_RS11645 ad93fc9900838c7b108ea97dc9fa5d3b 429 Pfam PF01595 Domain of unknown function DUF21 5 194 2.8E-44 T 05-07-2017 IPR002550 Domain of unknown function DUF21 K08M4_RS11645 ad93fc9900838c7b108ea97dc9fa5d3b 429 SMART SM01091 340 421 8.2E-20 T 05-07-2017 IPR005170 Transporter-associated domain K08M4_RS05460 84e307b4e508d236a0bd61ef3073d9a8 261 Hamap MF_02057 tRNA 5-carboxymethoxyuridine methyltransferase [cmoM]. 3 259 40.503 T 05-07-2017 IPR033664 tRNA 5-carboxymethoxyuridine methyltransferase GO:0008168 K08M4_RS05460 84e307b4e508d236a0bd61ef3073d9a8 261 Gene3D G3DSA:3.40.50.150 36 259 1.2E-26 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS05460 84e307b4e508d236a0bd61ef3073d9a8 261 Pfam PF08241 Methyltransferase domain 52 148 4.3E-12 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 K08M4_RS05460 84e307b4e508d236a0bd61ef3073d9a8 261 SUPERFAMILY SSF53335 6 250 4.96E-34 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS16635 c13d83796e899d33c2bd5183eefa5062 359 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 284 350 5.0E-13 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 K08M4_RS16635 c13d83796e899d33c2bd5183eefa5062 359 Gene3D G3DSA:2.40.30.10 10 107 6.2E-25 T 05-07-2017 K08M4_RS16635 c13d83796e899d33c2bd5183eefa5062 359 SUPERFAMILY SSF54292 262 359 5.37E-26 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 K08M4_RS16635 c13d83796e899d33c2bd5183eefa5062 359 SUPERFAMILY SSF52343 116 247 3.01E-31 T 05-07-2017 K08M4_RS16635 c13d83796e899d33c2bd5183eefa5062 359 Pfam PF00970 Oxidoreductase FAD-binding domain 19 107 8.3E-13 T 05-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 K08M4_RS16635 c13d83796e899d33c2bd5183eefa5062 359 Gene3D G3DSA:3.40.50.80 116 240 2.8E-30 T 05-07-2017 K08M4_RS16635 c13d83796e899d33c2bd5183eefa5062 359 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 309 317 - T 05-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 K08M4_RS16635 c13d83796e899d33c2bd5183eefa5062 359 Gene3D G3DSA:3.10.20.30 241 358 5.1E-29 T 05-07-2017 IPR012675 Beta-grasp domain K08M4_RS16635 c13d83796e899d33c2bd5183eefa5062 359 SUPERFAMILY SSF63380 7 109 4.33E-24 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 K08M4_RS16635 c13d83796e899d33c2bd5183eefa5062 359 Pfam PF00175 Oxidoreductase NAD-binding domain 122 224 8.7E-11 T 05-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 K08M4_RS07180 f614d905ebe037985351526e567a0242 611 SUPERFAMILY SSF52540 359 606 4.85E-90 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07180 f614d905ebe037985351526e567a0242 611 Gene3D G3DSA:3.40.50.300 367 597 4.0E-81 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07180 f614d905ebe037985351526e567a0242 611 Gene3D G3DSA:1.20.1560.10 38 346 1.1E-80 T 05-07-2017 K08M4_RS07180 f614d905ebe037985351526e567a0242 611 Pfam PF00005 ABC transporter 387 535 1.3E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS07180 f614d905ebe037985351526e567a0242 611 SMART SM00382 395 596 2.1E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS07180 f614d905ebe037985351526e567a0242 611 TIGRFAM TIGR02204 MsbA_rel: ABC transporter, permease/ATP-binding protein 32 606 1.6E-272 T 05-07-2017 IPR011918 ABC transporter, ATP-binding/permease protein K08M4_RS07180 f614d905ebe037985351526e567a0242 611 Pfam PF00664 ABC transporter transmembrane region 51 316 4.9E-49 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS07180 f614d905ebe037985351526e567a0242 611 SUPERFAMILY SSF90123 39 346 1.44E-75 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS07180 f614d905ebe037985351526e567a0242 611 ProSitePatterns PS00211 ABC transporters family signature. 507 521 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS20525 b4745554385206e3a44c95768155af8f 436 SUPERFAMILY SSF50331 298 415 3.68E-20 T 05-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal K08M4_RS20525 b4745554385206e3a44c95768155af8f 436 ProSitePatterns PS00211 ABC transporters family signature. 196 210 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS20525 b4745554385206e3a44c95768155af8f 436 Pfam PF00005 ABC transporter 82 223 2.4E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS20525 b4745554385206e3a44c95768155af8f 436 SUPERFAMILY SSF52540 64 305 2.93E-84 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20525 b4745554385206e3a44c95768155af8f 436 SMART SM00382 90 273 1.8E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS20525 b4745554385206e3a44c95768155af8f 436 Gene3D G3DSA:2.40.50.100 401 409 1.4E-7 T 05-07-2017 K08M4_RS20525 b4745554385206e3a44c95768155af8f 436 Gene3D G3DSA:2.40.50.100 301 339 1.4E-7 T 05-07-2017 K08M4_RS20525 b4745554385206e3a44c95768155af8f 436 Gene3D G3DSA:2.40.50.140 340 388 2.7E-6 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS20525 b4745554385206e3a44c95768155af8f 436 Gene3D G3DSA:3.40.50.300 59 297 9.9E-78 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08470 0fbbfc5b78ada8b1bd956147afe068a1 457 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 110 448 2.6E-118 T 05-07-2017 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 K08M4_RS08470 0fbbfc5b78ada8b1bd956147afe068a1 457 Gene3D G3DSA:3.60.120.10 21 454 7.5E-150 T 05-07-2017 IPR005801 ADC synthase GO:0009058 K08M4_RS08470 0fbbfc5b78ada8b1bd956147afe068a1 457 Pfam PF00425 chorismate binding enzyme 193 446 1.5E-94 T 05-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal K08M4_RS08470 0fbbfc5b78ada8b1bd956147afe068a1 457 Pfam PF04715 Anthranilate synthase component I, N terminal region 24 151 1.7E-26 T 05-07-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 K08M4_RS08470 0fbbfc5b78ada8b1bd956147afe068a1 457 SUPERFAMILY SSF56322 15 454 8.9E-142 T 05-07-2017 IPR005801 ADC synthase GO:0009058 K08M4_RS08470 0fbbfc5b78ada8b1bd956147afe068a1 457 PRINTS PR00095 Anthranilate synthase component I signature 308 321 7.6E-19 T 05-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 K08M4_RS08470 0fbbfc5b78ada8b1bd956147afe068a1 457 PRINTS PR00095 Anthranilate synthase component I signature 294 307 7.6E-19 T 05-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 K08M4_RS08470 0fbbfc5b78ada8b1bd956147afe068a1 457 PRINTS PR00095 Anthranilate synthase component I signature 403 417 7.6E-19 T 05-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 K08M4_RS08470 0fbbfc5b78ada8b1bd956147afe068a1 457 PRINTS PR00095 Anthranilate synthase component I signature 388 402 7.6E-19 T 05-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 K08M4_RS05195 bdccbab9159f76c7e425d74dd9846a32 405 SUPERFAMILY SSF46785 10 77 6.72E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05195 bdccbab9159f76c7e425d74dd9846a32 405 ProSitePatterns PS01125 ROK family signature. 218 245 - T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 K08M4_RS05195 bdccbab9159f76c7e425d74dd9846a32 405 Gene3D G3DSA:3.30.420.40 224 375 3.3E-53 T 05-07-2017 K08M4_RS05195 bdccbab9159f76c7e425d74dd9846a32 405 Pfam PF00480 ROK family 88 389 3.8E-69 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 K08M4_RS05195 bdccbab9159f76c7e425d74dd9846a32 405 Gene3D G3DSA:3.30.420.40 84 223 6.0E-35 T 05-07-2017 K08M4_RS05195 bdccbab9159f76c7e425d74dd9846a32 405 SUPERFAMILY SSF53067 86 395 1.52E-55 T 05-07-2017 K08M4_RS05195 bdccbab9159f76c7e425d74dd9846a32 405 Gene3D G3DSA:1.10.10.10 11 80 2.6E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 132 161 - T 05-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 Gene3D G3DSA:4.10.320.10 323 369 2.8E-20 T 05-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 25 54 - T 05-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 SUPERFAMILY SSF51230 211 301 5.5E-22 T 05-07-2017 IPR011053 Single hybrid motif K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 SUPERFAMILY SSF47005 322 367 2.22E-12 T 05-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 Gene3D G3DSA:2.40.50.100 111 185 4.7E-20 T 05-07-2017 K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 SUPERFAMILY SSF52777 393 634 2.67E-80 T 05-07-2017 K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 SUPERFAMILY SSF51230 1 92 1.44E-23 T 05-07-2017 IPR011053 Single hybrid motif K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 404 634 3.1E-79 T 05-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 SUPERFAMILY SSF51230 109 199 4.06E-21 T 05-07-2017 IPR011053 Single hybrid motif K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 233 262 - T 05-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 Gene3D G3DSA:2.40.50.100 210 302 2.5E-20 T 05-07-2017 K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 Gene3D G3DSA:2.40.50.100 1 92 3.4E-22 T 05-07-2017 K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 Pfam PF02817 e3 binding domain 329 363 8.6E-14 T 05-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 Pfam PF00364 Biotin-requiring enzyme 110 180 2.3E-19 T 05-07-2017 IPR000089 Biotin/lipoyl attachment K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 Pfam PF00364 Biotin-requiring enzyme 211 281 5.2E-21 T 05-07-2017 IPR000089 Biotin/lipoyl attachment K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 Pfam PF00364 Biotin-requiring enzyme 4 73 2.8E-21 T 05-07-2017 IPR000089 Biotin/lipoyl attachment K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 Gene3D G3DSA:3.30.559.10 394 635 1.1E-81 T 05-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 K08M4_RS02830 8bfc155f2b2fa28e6b4b302a8cd8d3d0 635 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 189 635 2.1E-202 T 05-07-2017 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 K08M4_RS02700 ecec03311abfce159ce18e1aa1bac39f 376 PIRSF PIRSF015658 1 376 5.7E-179 T 05-07-2017 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 K08M4_RS02700 ecec03311abfce159ce18e1aa1bac39f 376 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 20 374 6.1E-159 T 05-07-2017 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 K08M4_RS02700 ecec03311abfce159ce18e1aa1bac39f 376 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 19 370 1.3E-170 T 05-07-2017 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 K08M4_RS14745 866e0c90817a94e367db33ea4374608d 276 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 10 92 2.3E-22 T 05-07-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 K08M4_RS14745 866e0c90817a94e367db33ea4374608d 276 SUPERFAMILY SSF51735 106 273 2.22E-41 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS14745 866e0c90817a94e367db33ea4374608d 276 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 8 274 7.3E-84 T 05-07-2017 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 K08M4_RS14745 866e0c90817a94e367db33ea4374608d 276 Gene3D G3DSA:3.40.192.10 2 111 1.3E-35 T 05-07-2017 K08M4_RS14745 866e0c90817a94e367db33ea4374608d 276 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 5 273 31.702 T 05-07-2017 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 K08M4_RS14745 866e0c90817a94e367db33ea4374608d 276 SUPERFAMILY SSF53223 6 105 9.78E-30 T 05-07-2017 K08M4_RS14745 866e0c90817a94e367db33ea4374608d 276 Gene3D G3DSA:3.40.50.720 112 248 2.2E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS14745 866e0c90817a94e367db33ea4374608d 276 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 116 194 1.7E-12 T 05-07-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase K08M4_RS11130 f439dcb007776789f1204af2143382cb 114 SUPERFAMILY SSF54913 3 114 4.45E-47 T 05-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta K08M4_RS11130 f439dcb007776789f1204af2143382cb 114 ProSitePatterns PS00638 P-II protein C-terminal region signature. 85 98 - T 05-07-2017 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 K08M4_RS11130 f439dcb007776789f1204af2143382cb 114 SMART SM00938 6 107 2.7E-69 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 K08M4_RS11130 f439dcb007776789f1204af2143382cb 114 PRINTS PR00340 P-II protein signature 54 77 1.7E-44 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 K08M4_RS11130 f439dcb007776789f1204af2143382cb 114 PRINTS PR00340 P-II protein signature 25 43 1.7E-44 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 K08M4_RS11130 f439dcb007776789f1204af2143382cb 114 PRINTS PR00340 P-II protein signature 85 105 1.7E-44 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 K08M4_RS11130 f439dcb007776789f1204af2143382cb 114 PRINTS PR00340 P-II protein signature 4 19 1.7E-44 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 K08M4_RS11130 f439dcb007776789f1204af2143382cb 114 Pfam PF00543 Nitrogen regulatory protein P-II 6 107 4.2E-45 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 K08M4_RS11130 f439dcb007776789f1204af2143382cb 114 ProSitePatterns PS00496 P-II protein uridylation site. 48 53 - T 05-07-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 K08M4_RS11130 f439dcb007776789f1204af2143382cb 114 Gene3D G3DSA:3.30.70.120 3 114 5.9E-52 T 05-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal K08M4_RS11130 f439dcb007776789f1204af2143382cb 114 PIRSF PIRSF039144 3 114 2.7E-58 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 K08M4_RS07385 5e50293c1a651e821af634e25cdcc90b 699 Pfam PF10531 SLBB domain 494 537 2.8E-6 T 05-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS07385 5e50293c1a651e821af634e25cdcc90b 699 Pfam PF10531 SLBB domain 211 252 1.4E-5 T 05-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS07385 5e50293c1a651e821af634e25cdcc90b 699 Pfam PF10531 SLBB domain 589 628 8.7E-6 T 05-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS07385 5e50293c1a651e821af634e25cdcc90b 699 Pfam PF10531 SLBB domain 395 439 5.5E-6 T 05-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS07385 5e50293c1a651e821af634e25cdcc90b 699 Pfam PF10531 SLBB domain 103 147 7.9E-6 T 05-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS07385 5e50293c1a651e821af634e25cdcc90b 699 Pfam PF10531 SLBB domain 298 350 6.2E-11 T 05-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS07385 5e50293c1a651e821af634e25cdcc90b 699 Gene3D G3DSA:3.30.1950.10 31 90 2.2E-8 T 05-07-2017 K08M4_RS07385 5e50293c1a651e821af634e25cdcc90b 699 Gene3D G3DSA:3.10.560.10 585 670 8.6E-14 T 05-07-2017 K08M4_RS07385 5e50293c1a651e821af634e25cdcc90b 699 Gene3D G3DSA:3.10.560.10 207 287 6.7E-15 T 05-07-2017 K08M4_RS07385 5e50293c1a651e821af634e25cdcc90b 699 Gene3D G3DSA:3.10.560.10 392 457 1.4E-9 T 05-07-2017 K08M4_RS07385 5e50293c1a651e821af634e25cdcc90b 699 Gene3D G3DSA:3.10.560.10 296 377 9.4E-14 T 05-07-2017 K08M4_RS07385 5e50293c1a651e821af634e25cdcc90b 699 Gene3D G3DSA:3.10.560.10 95 180 5.0E-14 T 05-07-2017 K08M4_RS07385 5e50293c1a651e821af634e25cdcc90b 699 Gene3D G3DSA:3.10.560.10 486 575 3.7E-15 T 05-07-2017 K08M4_RS07385 5e50293c1a651e821af634e25cdcc90b 699 Pfam PF02563 Polysaccharide biosynthesis/export protein 29 96 3.8E-9 T 05-07-2017 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 K08M4_RS12725 2cc1ab8bfd20eed2b8f578b2a8db47bc 209 ProSitePatterns PS00893 Nudix box signature. 96 117 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 K08M4_RS12725 2cc1ab8bfd20eed2b8f578b2a8db47bc 209 Gene3D G3DSA:3.90.79.10 14 201 2.6E-52 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS12725 2cc1ab8bfd20eed2b8f578b2a8db47bc 209 SUPERFAMILY SSF55811 3 207 2.23E-45 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS12725 2cc1ab8bfd20eed2b8f578b2a8db47bc 209 Pfam PF00293 NUDIX domain 59 175 1.1E-9 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 K08M4_RS12725 2cc1ab8bfd20eed2b8f578b2a8db47bc 209 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 14 198 2.4E-57 T 05-07-2017 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 K08M4_RS06295 1c79b3baed9e94491b75d8797667a506 158 SUPERFAMILY SSF81301 1 155 2.94E-39 T 05-07-2017 K08M4_RS12435 be6d0d60dfb64b90d82f54a0e57df105 238 SMART SM00862 156 232 2.4E-14 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS12435 be6d0d60dfb64b90d82f54a0e57df105 238 Pfam PF00072 Response regulator receiver domain 6 113 1.7E-27 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS12435 be6d0d60dfb64b90d82f54a0e57df105 238 SUPERFAMILY SSF46894 137 233 3.68E-21 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS12435 be6d0d60dfb64b90d82f54a0e57df105 238 Gene3D G3DSA:1.10.10.10 134 233 3.6E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS12435 be6d0d60dfb64b90d82f54a0e57df105 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 232 2.8E-17 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS12435 be6d0d60dfb64b90d82f54a0e57df105 238 SMART SM00448 4 114 1.5E-37 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS12435 be6d0d60dfb64b90d82f54a0e57df105 238 SUPERFAMILY SSF52172 2 131 2.13E-36 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS12435 be6d0d60dfb64b90d82f54a0e57df105 238 Gene3D G3DSA:3.40.50.2300 2 130 1.7E-36 T 05-07-2017 K08M4_RS12125 7d577e3017b723eedd47f30f446af4fb 242 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 1 240 36.277 T 05-07-2017 IPR017689 Outer membrane protein assembly factor BamD K08M4_RS12125 7d577e3017b723eedd47f30f446af4fb 242 Gene3D G3DSA:1.25.40.10 33 182 1.2E-4 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS12125 7d577e3017b723eedd47f30f446af4fb 242 Pfam PF13525 Outer membrane lipoprotein 26 232 1.7E-77 T 05-07-2017 K08M4_RS12125 7d577e3017b723eedd47f30f446af4fb 242 SUPERFAMILY SSF48452 30 119 1.34E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS12125 7d577e3017b723eedd47f30f446af4fb 242 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 4 239 8.1E-77 T 05-07-2017 IPR017689 Outer membrane protein assembly factor BamD K08M4_RS08030 492df8b7531f23adc7d9aa967fb68124 239 SUPERFAMILY SSF48008 93 226 3.66E-24 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS08030 492df8b7531f23adc7d9aa967fb68124 239 Gene3D G3DSA:1.20.120.530 91 235 5.0E-32 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS08030 492df8b7531f23adc7d9aa967fb68124 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 87 3.7E-15 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS08030 492df8b7531f23adc7d9aa967fb68124 239 SUPERFAMILY SSF46785 23 115 1.42E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS08030 492df8b7531f23adc7d9aa967fb68124 239 SMART SM00895 97 224 9.8E-24 T 05-07-2017 IPR011711 GntR, C-terminal K08M4_RS08030 492df8b7531f23adc7d9aa967fb68124 239 SMART SM00345 29 87 6.5E-14 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS08030 492df8b7531f23adc7d9aa967fb68124 239 Pfam PF07729 FCD domain 97 222 1.0E-26 T 05-07-2017 IPR011711 GntR, C-terminal K08M4_RS08030 492df8b7531f23adc7d9aa967fb68124 239 Gene3D G3DSA:1.10.10.10 19 87 5.5E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS18970 e5ec9b1b6ff43731ad511107e3957d74 207 SUPERFAMILY SSF51182 97 204 5.06E-24 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS18970 e5ec9b1b6ff43731ad511107e3957d74 207 SMART SM00530 31 86 8.1E-13 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 K08M4_RS18970 e5ec9b1b6ff43731ad511107e3957d74 207 Pfam PF01381 Helix-turn-helix 32 84 1.1E-11 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 K08M4_RS18970 e5ec9b1b6ff43731ad511107e3957d74 207 Gene3D G3DSA:1.10.260.40 28 127 8.0E-21 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS18970 e5ec9b1b6ff43731ad511107e3957d74 207 Gene3D G3DSA:2.60.120.10 128 205 1.5E-11 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS18970 e5ec9b1b6ff43731ad511107e3957d74 207 SUPERFAMILY SSF47413 26 90 1.21E-14 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS18970 e5ec9b1b6ff43731ad511107e3957d74 207 Pfam PF07883 Cupin domain 147 204 2.2E-9 T 05-07-2017 IPR013096 Cupin 2, conserved barrel K08M4_RS15510 cfc2ea992a92f613864cd7e4d236924b 282 Gene3D G3DSA:2.60.120.600 136 277 2.7E-35 T 05-07-2017 IPR010621 Domain of unknown function DUF1214 K08M4_RS15510 cfc2ea992a92f613864cd7e4d236924b 282 SUPERFAMILY SSF160935 1 276 1.57E-57 T 05-07-2017 K08M4_RS15510 cfc2ea992a92f613864cd7e4d236924b 282 Pfam PF06742 Protein of unknown function (DUF1214) 155 260 3.1E-23 T 05-07-2017 IPR010621 Domain of unknown function DUF1214 K08M4_RS10300 8e3e2698534776c5fb5bce68881ada2e 306 Pfam PF03601 Conserved hypothetical protein 698 25 287 1.0E-54 T 05-07-2017 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 K08M4_RS18695 696e9fcc627ceaf2604bc2eed219aeec 419 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 13 418 2.2E-133 T 05-07-2017 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) K08M4_RS18695 696e9fcc627ceaf2604bc2eed219aeec 419 SUPERFAMILY SSF56935 22 419 5.49E-96 T 05-07-2017 K08M4_RS18695 696e9fcc627ceaf2604bc2eed219aeec 419 Gene3D G3DSA:2.40.160.60 22 418 2.2E-127 T 05-07-2017 K08M4_RS11190 bfa05a0ba7c74953da76a31c3ad13de6 452 Gene3D G3DSA:2.30.42.10 95 184 4.6E-10 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS11190 bfa05a0ba7c74953da76a31c3ad13de6 452 Gene3D G3DSA:2.30.42.10 202 291 1.0E-17 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS11190 bfa05a0ba7c74953da76a31c3ad13de6 452 SUPERFAMILY SSF50156 196 291 5.13E-16 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS11190 bfa05a0ba7c74953da76a31c3ad13de6 452 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 4 452 2.3E-136 T 05-07-2017 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 K08M4_RS11190 bfa05a0ba7c74953da76a31c3ad13de6 452 SMART SM00228 115 186 0.29 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS11190 bfa05a0ba7c74953da76a31c3ad13de6 452 SMART SM00228 212 281 3.4E-8 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS11190 bfa05a0ba7c74953da76a31c3ad13de6 452 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 224 276 2.3E-7 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS11190 bfa05a0ba7c74953da76a31c3ad13de6 452 SUPERFAMILY SSF50156 90 186 2.5E-10 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS11190 bfa05a0ba7c74953da76a31c3ad13de6 452 Pfam PF02163 Peptidase family M50 11 440 1.4E-86 T 05-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 Pfam PF00512 His Kinase A (phospho-acceptor) domain 283 345 1.8E-13 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 Pfam PF00072 Response regulator receiver domain 529 638 2.7E-17 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 SUPERFAMILY SSF55785 140 267 1.47E-24 T 05-07-2017 IPR000014 PAS domain K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 Gene3D G3DSA:1.10.287.130 274 343 4.5E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 Gene3D G3DSA:3.30.565.10 349 511 8.3E-40 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 Pfam PF08448 PAS fold 162 271 1.4E-17 T 05-07-2017 IPR013656 PAS fold-4 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 SMART SM00448 527 638 4.1E-20 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 Gene3D G3DSA:1.20.120.160 696 794 3.5E-30 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 SUPERFAMILY SSF47384 270 347 4.12E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 SUPERFAMILY SSF55874 336 507 5.89E-39 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 Pfam PF01627 Hpt domain 708 776 1.2E-11 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 SUPERFAMILY SSF47226 680 794 6.02E-28 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 SMART SM00388 282 347 2.8E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 152 276 2.9E-19 T 05-07-2017 IPR000014 PAS domain K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 Gene3D G3DSA:1.10.287.970 1 89 5.3E-39 T 05-07-2017 IPR027460 Aerobic respiration control sensor protein ArcB, transmembrane domain K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 395 507 5.8E-25 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 Gene3D G3DSA:3.40.50.2300 520 643 3.3E-28 T 05-07-2017 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 Gene3D G3DSA:3.30.450.20 142 267 2.9E-23 T 05-07-2017 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 SMART SM00091 155 221 8.9E-8 T 05-07-2017 IPR000014 PAS domain K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 SMART SM00073 695 792 5.9E-6 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 SMART SM00387 394 510 7.9E-32 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 SUPERFAMILY SSF52172 525 642 1.1E-24 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 488 1.8E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 448 1.8E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 462 1.8E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 507 1.8E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS12445 12a7441022f9bb4b935e2a9b0453bca7 795 PIRSF PIRSF003182 1 795 0.0 T 05-07-2017 IPR014409 Signal transduction histidine kinase, hybrid-type, aerobic respiration control ArcB GO:0000155|GO:0000160|GO:0004673|GO:0016021 K08M4_RS11480 b32405e6d5ba51c83a5353a62b79550f 210 Hamap MF_00428 Na(+)-translocating NADH-quinone reductase subunit D [nqrD]. 2 207 37.09 T 05-07-2017 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 K08M4_RS11480 b32405e6d5ba51c83a5353a62b79550f 210 Pfam PF02508 Rnf-Nqr subunit, membrane protein 9 195 8.0E-63 T 05-07-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 K08M4_RS11480 b32405e6d5ba51c83a5353a62b79550f 210 PIRSF PIRSF006102 3 210 1.3E-72 T 05-07-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 K08M4_RS11480 b32405e6d5ba51c83a5353a62b79550f 210 TIGRFAM TIGR01939 nqrD: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit 3 207 4.0E-109 T 05-07-2017 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 K08M4_RS09885 27c953a46f4983d203daaa4bc5f8bbf8 116 Gene3D G3DSA:3.30.428.10 3 110 1.5E-35 T 05-07-2017 IPR011146 HIT-like domain GO:0003824 K08M4_RS09885 27c953a46f4983d203daaa4bc5f8bbf8 116 ProSitePatterns PS00892 HIT domain signature. 88 106 - T 05-07-2017 IPR019808 Histidine triad, conserved site K08M4_RS09885 27c953a46f4983d203daaa4bc5f8bbf8 116 PRINTS PR00332 Histidine triad family signature 6 22 9.3E-19 T 05-07-2017 IPR001310 Histidine triad (HIT) protein K08M4_RS09885 27c953a46f4983d203daaa4bc5f8bbf8 116 PRINTS PR00332 Histidine triad family signature 27 45 9.3E-19 T 05-07-2017 IPR001310 Histidine triad (HIT) protein K08M4_RS09885 27c953a46f4983d203daaa4bc5f8bbf8 116 PRINTS PR00332 Histidine triad family signature 95 105 9.3E-19 T 05-07-2017 IPR001310 Histidine triad (HIT) protein K08M4_RS09885 27c953a46f4983d203daaa4bc5f8bbf8 116 Pfam PF01230 HIT domain 13 109 9.2E-29 T 05-07-2017 IPR001310 Histidine triad (HIT) protein K08M4_RS09885 27c953a46f4983d203daaa4bc5f8bbf8 116 SUPERFAMILY SSF54197 2 113 1.42E-34 T 05-07-2017 IPR011146 HIT-like domain GO:0003824 K08M4_RS06780 b209eaa77a25f7d6be3b6eac4e0b0bbf 700 Gene3D G3DSA:1.25.40.20 448 578 3.2E-19 T 05-07-2017 IPR020683 Ankyrin repeat-containing domain K08M4_RS06780 b209eaa77a25f7d6be3b6eac4e0b0bbf 700 Gene3D G3DSA:1.25.40.20 653 700 3.2E-19 T 05-07-2017 IPR020683 Ankyrin repeat-containing domain K08M4_RS06780 b209eaa77a25f7d6be3b6eac4e0b0bbf 700 SMART SM00248 450 479 0.0013 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 K08M4_RS06780 b209eaa77a25f7d6be3b6eac4e0b0bbf 700 SMART SM00248 529 558 130.0 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 K08M4_RS06780 b209eaa77a25f7d6be3b6eac4e0b0bbf 700 SMART SM00248 674 700 1400.0 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 K08M4_RS06780 b209eaa77a25f7d6be3b6eac4e0b0bbf 700 SMART SM00248 632 667 2100.0 T 05-07-2017 IPR002110 Ankyrin repeat GO:0005515 K08M4_RS06780 b209eaa77a25f7d6be3b6eac4e0b0bbf 700 SUPERFAMILY SSF48403 450 593 3.48E-17 T 05-07-2017 IPR020683 Ankyrin repeat-containing domain K08M4_RS06780 b209eaa77a25f7d6be3b6eac4e0b0bbf 700 SUPERFAMILY SSF48403 655 699 3.48E-17 T 05-07-2017 IPR020683 Ankyrin repeat-containing domain K08M4_RS04785 679e83b1f1dc80fb6a6c73b7af1bd85d 372 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 144 354 9.3E-57 T 05-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 K08M4_RS04785 679e83b1f1dc80fb6a6c73b7af1bd85d 372 SUPERFAMILY SSF51735 1 147 1.37E-50 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04785 679e83b1f1dc80fb6a6c73b7af1bd85d 372 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 262 276 - T 05-07-2017 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS04785 679e83b1f1dc80fb6a6c73b7af1bd85d 372 PIRSF PIRSF000148 1 372 6.4E-67 T 05-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS04785 679e83b1f1dc80fb6a6c73b7af1bd85d 372 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 121 1.0E-20 T 05-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 K08M4_RS04785 679e83b1f1dc80fb6a6c73b7af1bd85d 372 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 1 367 2.8E-187 T 05-07-2017 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS04785 679e83b1f1dc80fb6a6c73b7af1bd85d 372 Gene3D G3DSA:3.40.50.720 1 142 1.0E-56 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04785 679e83b1f1dc80fb6a6c73b7af1bd85d 372 SUPERFAMILY SSF55347 134 355 5.12E-79 T 05-07-2017 K08M4_RS04785 679e83b1f1dc80fb6a6c73b7af1bd85d 372 Gene3D G3DSA:3.30.360.10 143 351 8.2E-77 T 05-07-2017 K08M4_RS04785 679e83b1f1dc80fb6a6c73b7af1bd85d 372 SMART SM00859 2 122 4.5E-24 T 05-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 K08M4_RS04785 679e83b1f1dc80fb6a6c73b7af1bd85d 372 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 368 31.819 T 05-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS04380 4010fb68d415b0307ce896ecf64bee1e 310 PIRSF PIRSF037167 2 307 2.2E-149 T 05-07-2017 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 K08M4_RS04380 4010fb68d415b0307ce896ecf64bee1e 310 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 6 300 54.135 T 05-07-2017 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 K08M4_RS04380 4010fb68d415b0307ce896ecf64bee1e 310 Pfam PF05175 Methyltransferase small domain 134 216 1.8E-17 T 05-07-2017 IPR007848 Methyltransferase small domain GO:0008168 K08M4_RS04380 4010fb68d415b0307ce896ecf64bee1e 310 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 13 295 6.4E-138 T 05-07-2017 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 K08M4_RS04380 4010fb68d415b0307ce896ecf64bee1e 310 Gene3D G3DSA:3.40.50.150 108 292 3.4E-54 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS04380 4010fb68d415b0307ce896ecf64bee1e 310 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 15 303 4.6E-97 T 05-07-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 K08M4_RS04380 4010fb68d415b0307ce896ecf64bee1e 310 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 204 210 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 K08M4_RS04380 4010fb68d415b0307ce896ecf64bee1e 310 SUPERFAMILY SSF53335 16 294 6.93E-50 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS04380 4010fb68d415b0307ce896ecf64bee1e 310 Gene3D G3DSA:1.10.8.10 15 106 3.6E-6 T 05-07-2017 K08M4_RS10960 788aa900b28527b991eecd6ae7d5c8e5 287 SUPERFAMILY SSF82861 24 107 6.93E-11 T 05-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 K08M4_RS10960 788aa900b28527b991eecd6ae7d5c8e5 287 SUPERFAMILY SSF82689 177 277 7.06E-26 T 05-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 K08M4_RS10960 788aa900b28527b991eecd6ae7d5c8e5 287 Pfam PF00924 Mechanosensitive ion channel 67 267 1.5E-48 T 05-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 K08M4_RS10960 788aa900b28527b991eecd6ae7d5c8e5 287 Gene3D G3DSA:3.30.70.100 180 265 2.8E-20 T 05-07-2017 K08M4_RS10960 788aa900b28527b991eecd6ae7d5c8e5 287 Gene3D G3DSA:2.30.30.60 124 173 3.2E-18 T 05-07-2017 K08M4_RS10960 788aa900b28527b991eecd6ae7d5c8e5 287 SUPERFAMILY SSF50182 108 174 4.58E-18 T 05-07-2017 IPR010920 LSM domain K08M4_RS16560 af90a9feffcd0a5f7270a064dac21f95 425 Gene3D G3DSA:3.20.20.140 62 363 1.0E-122 T 05-07-2017 K08M4_RS16560 af90a9feffcd0a5f7270a064dac21f95 425 SUPERFAMILY SSF51338 1 76 4.43E-5 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS16560 af90a9feffcd0a5f7270a064dac21f95 425 Gene3D G3DSA:2.30.40.10 2 61 1.7E-5 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS16560 af90a9feffcd0a5f7270a064dac21f95 425 SUPERFAMILY SSF51556 54 372 4.42E-104 T 05-07-2017 IPR032466 Metal-dependent hydrolase K08M4_RS16560 af90a9feffcd0a5f7270a064dac21f95 425 Pfam PF07969 Amidohydrolase family 43 403 1.5E-49 T 05-07-2017 IPR013108 Amidohydrolase 3 K08M4_RS19085 d520a9eebebf2a3d66ac567bdae74e2f 397 Gene3D G3DSA:1.20.1250.20 15 199 4.9E-15 T 05-07-2017 K08M4_RS19085 d520a9eebebf2a3d66ac567bdae74e2f 397 Pfam PF07690 Major Facilitator Superfamily 26 352 3.1E-21 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS19085 d520a9eebebf2a3d66ac567bdae74e2f 397 SUPERFAMILY SSF103473 6 394 4.05E-40 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS19085 d520a9eebebf2a3d66ac567bdae74e2f 397 Gene3D G3DSA:1.20.1250.20 211 394 1.2E-13 T 05-07-2017 K08M4_RS20025 096d10a5f00da2c5af8d357d5333d723 83 Pfam PF04606 Ogr/Delta-like zinc finger 5 50 4.3E-17 T 05-07-2017 IPR007684 Zinc finger, Ogr/Delta-type K08M4_RS00300 0a538c83a6a50748c3a85394eb6338d4 613 SUPERFAMILY SSF143968 323 459 7.72E-50 T 05-07-2017 K08M4_RS00300 0a538c83a6a50748c3a85394eb6338d4 613 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 455 1.7E-161 T 05-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 K08M4_RS00300 0a538c83a6a50748c3a85394eb6338d4 613 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 431 2.5E-161 T 05-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 K08M4_RS00300 0a538c83a6a50748c3a85394eb6338d4 613 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 476 566 3.9E-20 T 05-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 K08M4_RS00300 0a538c83a6a50748c3a85394eb6338d4 613 Gene3D G3DSA:1.20.5.570 580 612 1.9E-16 T 05-07-2017 K08M4_RS00300 0a538c83a6a50748c3a85394eb6338d4 613 Gene3D G3DSA:3.40.1670.10 337 453 6.0E-47 T 05-07-2017 K08M4_RS00300 0a538c83a6a50748c3a85394eb6338d4 613 Gene3D G3DSA:3.40.1670.10 481 578 5.0E-29 T 05-07-2017 K08M4_RS00300 0a538c83a6a50748c3a85394eb6338d4 613 SUPERFAMILY SSF143968 482 612 3.53E-35 T 05-07-2017 K08M4_RS00300 0a538c83a6a50748c3a85394eb6338d4 613 SUPERFAMILY SSF50475 3 322 7.06E-123 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 K08M4_RS08090 ee077f808f44d6074f174737e9917dfa 231 Gene3D G3DSA:3.40.50.2300 5 130 2.8E-28 T 05-07-2017 K08M4_RS08090 ee077f808f44d6074f174737e9917dfa 231 PIRSF PIRSF006171 3 231 8.7E-81 T 05-07-2017 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 K08M4_RS08090 ee077f808f44d6074f174737e9917dfa 231 Pfam PF12431 Transcriptional regulator 134 163 1.2E-7 T 05-07-2017 IPR028141 Transcriptional regulator K08M4_RS08090 ee077f808f44d6074f174737e9917dfa 231 SMART SM00448 5 118 1.0E-23 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS08090 ee077f808f44d6074f174737e9917dfa 231 SUPERFAMILY SSF52172 6 138 8.82E-32 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS08090 ee077f808f44d6074f174737e9917dfa 231 Pfam PF00072 Response regulator receiver domain 7 118 5.9E-21 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS20090 587db9ba34adf07d2e803bffebb3ff22 508 Pfam PF07669 Eco57I restriction-modification methylase 145 249 7.5E-9 T 05-07-2017 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 K08M4_RS20090 587db9ba34adf07d2e803bffebb3ff22 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 61 75 2.9E-10 T 05-07-2017 K08M4_RS20090 587db9ba34adf07d2e803bffebb3ff22 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 176 200 2.9E-10 T 05-07-2017 K08M4_RS20090 587db9ba34adf07d2e803bffebb3ff22 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 36 52 2.9E-10 T 05-07-2017 K08M4_RS20090 587db9ba34adf07d2e803bffebb3ff22 508 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 145 157 2.9E-10 T 05-07-2017 K08M4_RS20090 587db9ba34adf07d2e803bffebb3ff22 508 SUPERFAMILY SSF53335 24 254 1.47E-27 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS20090 587db9ba34adf07d2e803bffebb3ff22 508 Gene3D G3DSA:3.40.50.150 57 258 3.1E-21 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 Gene3D G3DSA:3.40.1160.10 111 299 2.2E-67 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 Gene3D G3DSA:3.40.1160.10 1 49 2.2E-67 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 472 606 1.9E-26 T 05-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 Gene3D G3DSA:3.30.360.10 636 791 1.3E-53 T 05-07-2017 K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 660 682 - T 05-07-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 SUPERFAMILY SSF51735 463 636 2.33E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 PIRSF PIRSF000727 1 817 0.0 T 05-07-2017 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+2.7.2.4+1.1.1.3|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4+1.1.1.3|KEGG: 00300+2.7.2.4+1.1.1.3|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 05-07-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 SUPERFAMILY SSF55347 614 797 4.45E-50 T 05-07-2017 K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 SUPERFAMILY SSF55021 383 476 4.58E-22 T 05-07-2017 K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 SUPERFAMILY SSF53633 1 298 9.95E-77 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 Pfam PF13840 ACT domain 394 456 1.5E-7 T 05-07-2017 IPR027795 GATS-like ACT domain K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 SUPERFAMILY SSF55021 303 381 1.56E-22 T 05-07-2017 K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 Gene3D G3DSA:3.40.50.720 466 635 9.9E-64 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 Pfam PF01842 ACT domain 324 377 3.4E-9 T 05-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 Pfam PF00742 Homoserine dehydrogenase 614 810 2.7E-46 T 05-07-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 460 2.1E-132 T 05-07-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS12415 c2630799d37d9776f91fda952853b508 819 Pfam PF00696 Amino acid kinase family 2 284 3.4E-52 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS18870 b204284050fc73074846f14ce657d584 362 Pfam PF13437 HlyD family secretion protein 167 273 3.6E-8 T 05-07-2017 K08M4_RS18870 b204284050fc73074846f14ce657d584 362 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 47 356 1.3E-58 T 05-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 K08M4_RS18870 b204284050fc73074846f14ce657d584 362 SUPERFAMILY SSF111369 62 281 1.57E-27 T 05-07-2017 K08M4_RS18870 b204284050fc73074846f14ce657d584 362 Pfam PF13533 Biotin-lipoyl like 74 117 4.5E-10 T 05-07-2017 K08M4_RS18870 b204284050fc73074846f14ce657d584 362 Gene3D G3DSA:2.40.50.100 73 104 1.7E-13 T 05-07-2017 K08M4_RS18870 b204284050fc73074846f14ce657d584 362 Gene3D G3DSA:2.40.50.100 165 197 1.7E-13 T 05-07-2017 K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 Gene3D G3DSA:3.30.565.10 271 428 3.6E-45 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 Pfam PF00072 Response regulator receiver domain 452 561 3.6E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 Pfam PF00512 His Kinase A (phospho-acceptor) domain 206 269 3.1E-17 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 SUPERFAMILY SSF47384 193 269 2.35E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 SUPERFAMILY SSF55874 258 429 1.57E-46 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 316 426 3.9E-29 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 SMART SM00387 316 427 4.4E-37 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 SMART SM00388 204 269 6.7E-19 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 Gene3D G3DSA:3.40.50.2300 450 564 1.7E-37 T 05-07-2017 K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 Gene3D G3DSA:1.10.287.130 196 265 2.0E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 380 2.3E-17 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 424 2.3E-17 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 405 2.3E-17 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 366 2.3E-17 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 SUPERFAMILY SSF52172 450 564 6.83E-35 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS08480 b98ca882e5c9a1c9b96fcbedc1cfc724 565 SMART SM00448 450 561 3.0E-33 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS17715 fdf3aa8a5d03c41a963f365492383f9e 119 SUPERFAMILY SSF52833 40 118 1.55E-20 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS17715 fdf3aa8a5d03c41a963f365492383f9e 119 Gene3D G3DSA:3.40.30.10 48 118 6.2E-24 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS17715 fdf3aa8a5d03c41a963f365492383f9e 119 Pfam PF13417 Glutathione S-transferase, N-terminal domain 43 118 3.2E-13 T 05-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 K08M4_RS02745 8715b9c22b6c8039d4253df35495c159 464 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 05-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 K08M4_RS02745 8715b9c22b6c8039d4253df35495c159 464 SMART SM00963 1 86 8.2E-36 T 05-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 K08M4_RS02745 8715b9c22b6c8039d4253df35495c159 464 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 8.6E-22 T 05-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 K08M4_RS02745 8715b9c22b6c8039d4253df35495c159 464 SUPERFAMILY SSF47446 329 430 8.83E-38 T 05-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 K08M4_RS02745 8715b9c22b6c8039d4253df35495c159 464 Gene3D G3DSA:1.10.260.30 329 432 4.5E-41 T 05-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 K08M4_RS02745 8715b9c22b6c8039d4253df35495c159 464 Pfam PF00448 SRP54-type protein, GTPase domain 100 296 8.5E-74 T 05-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 K08M4_RS02745 8715b9c22b6c8039d4253df35495c159 464 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 1.7E-177 T 05-07-2017 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 K08M4_RS02745 8715b9c22b6c8039d4253df35495c159 464 Gene3D G3DSA:3.40.50.300 95 297 2.2E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02745 8715b9c22b6c8039d4253df35495c159 464 SUPERFAMILY SSF52540 42 353 4.25E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02745 8715b9c22b6c8039d4253df35495c159 464 SMART SM00382 99 247 1.3E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS02745 8715b9c22b6c8039d4253df35495c159 464 SMART SM00962 100 296 2.4E-113 T 05-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 K08M4_RS02745 8715b9c22b6c8039d4253df35495c159 464 Pfam PF02978 Signal peptide binding domain 329 427 2.7E-33 T 05-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 K08M4_RS02745 8715b9c22b6c8039d4253df35495c159 464 Gene3D G3DSA:1.20.120.140 2 89 2.3E-35 T 05-07-2017 K08M4_RS02745 8715b9c22b6c8039d4253df35495c159 464 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 439 34.102 T 05-07-2017 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 K08M4_RS04915 4f835dffb004ea133c60247f13e4d770 329 Pfam PF13353 4Fe-4S single cluster domain 23 125 1.1E-8 T 05-07-2017 K08M4_RS04915 4f835dffb004ea133c60247f13e4d770 329 Pfam PF04055 Radical SAM superfamily 19 181 5.1E-27 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS04915 4f835dffb004ea133c60247f13e4d770 329 SMART SM00729 14 216 5.2E-6 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 K08M4_RS04915 4f835dffb004ea133c60247f13e4d770 329 SUPERFAMILY SSF102114 6 278 1.01E-69 T 05-07-2017 K08M4_RS04915 4f835dffb004ea133c60247f13e4d770 329 Gene3D G3DSA:3.20.20.70 5 306 2.4E-71 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS04915 4f835dffb004ea133c60247f13e4d770 329 Pfam PF06463 Molybdenum Cofactor Synthesis C 186 312 3.1E-39 T 05-07-2017 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS04915 4f835dffb004ea133c60247f13e4d770 329 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 6 329 8.1E-105 T 05-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS04915 4f835dffb004ea133c60247f13e4d770 329 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 5 329 36.645 T 05-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS12800 1e446a60004948d18ffdfbf1c40fded3 119 Gene3D G3DSA:3.30.1130.10 2 117 3.4E-41 T 05-07-2017 K08M4_RS12800 1e446a60004948d18ffdfbf1c40fded3 119 SMART SM00905 6 116 2.1E-46 T 05-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS12800 1e446a60004948d18ffdfbf1c40fded3 119 TIGRFAM TIGR00526 folB_dom: FolB domain 4 117 4.1E-35 T 05-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS12800 1e446a60004948d18ffdfbf1c40fded3 119 SUPERFAMILY SSF55620 3 117 1.17E-35 T 05-07-2017 K08M4_RS12800 1e446a60004948d18ffdfbf1c40fded3 119 Pfam PF02152 Dihydroneopterin aldolase 6 115 7.5E-31 T 05-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS12800 1e446a60004948d18ffdfbf1c40fded3 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 4 116 2.5E-28 T 05-07-2017 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS21405 92c47a642a560036ad692f882b65ba22 282 Gene3D G3DSA:3.40.50.1820 63 277 1.1E-29 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS21405 92c47a642a560036ad692f882b65ba22 282 SUPERFAMILY SSF53474 22 272 4.09E-28 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS21405 92c47a642a560036ad692f882b65ba22 282 Pfam PF12146 Serine aminopeptidase, S33 83 189 3.4E-10 T 05-07-2017 IPR022742 Serine aminopeptidase, S33 K08M4_RS10025 0755ba81b137fd1807c401bbd4990391 303 Gene3D G3DSA:3.40.50.1980 130 302 1.3E-51 T 05-07-2017 K08M4_RS10025 0755ba81b137fd1807c401bbd4990391 303 Gene3D G3DSA:3.40.50.1980 37 126 3.0E-34 T 05-07-2017 K08M4_RS10025 0755ba81b137fd1807c401bbd4990391 303 Pfam PF01497 Periplasmic binding protein 43 278 1.9E-26 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 K08M4_RS10025 0755ba81b137fd1807c401bbd4990391 303 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 60 78 1.8E-15 T 05-07-2017 IPR008091 Ferrichrome-binding periplasmic protein K08M4_RS10025 0755ba81b137fd1807c401bbd4990391 303 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 281 294 1.8E-15 T 05-07-2017 IPR008091 Ferrichrome-binding periplasmic protein K08M4_RS10025 0755ba81b137fd1807c401bbd4990391 303 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 91 106 1.8E-15 T 05-07-2017 IPR008091 Ferrichrome-binding periplasmic protein K08M4_RS10025 0755ba81b137fd1807c401bbd4990391 303 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 216 234 1.8E-15 T 05-07-2017 IPR008091 Ferrichrome-binding periplasmic protein K08M4_RS10025 0755ba81b137fd1807c401bbd4990391 303 SUPERFAMILY SSF53807 38 300 7.85E-58 T 05-07-2017 K08M4_RS15485 6060195b12084fa0dc7ad6ef5fa76886 510 Pfam PF13091 PLD-like domain 77 226 1.2E-19 T 05-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 K08M4_RS15485 6060195b12084fa0dc7ad6ef5fa76886 510 Pfam PF13091 PLD-like domain 314 458 8.3E-16 T 05-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 K08M4_RS15485 6060195b12084fa0dc7ad6ef5fa76886 510 SUPERFAMILY SSF56024 302 472 1.31E-22 T 05-07-2017 K08M4_RS15485 6060195b12084fa0dc7ad6ef5fa76886 510 SUPERFAMILY SSF56024 26 260 3.59E-44 T 05-07-2017 K08M4_RS15485 6060195b12084fa0dc7ad6ef5fa76886 510 SMART SM00155 405 432 0.0017 T 05-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 K08M4_RS15485 6060195b12084fa0dc7ad6ef5fa76886 510 SMART SM00155 167 194 0.0038 T 05-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 K08M4_RS15485 6060195b12084fa0dc7ad6ef5fa76886 510 Gene3D G3DSA:3.30.870.10 314 493 9.4E-25 T 05-07-2017 K08M4_RS15485 6060195b12084fa0dc7ad6ef5fa76886 510 Gene3D G3DSA:3.30.870.10 57 248 1.4E-40 T 05-07-2017 K08M4_RS11530 463b301b8e58196933157632560ee5fd 295 SUPERFAMILY SSF111364 54 295 6.28E-80 T 05-07-2017 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 K08M4_RS11530 463b301b8e58196933157632560ee5fd 295 Pfam PF03502 Nucleoside-specific channel-forming protein, Tsx 54 295 8.6E-91 T 05-07-2017 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 K08M4_RS11530 463b301b8e58196933157632560ee5fd 295 Gene3D G3DSA:2.40.230.20 47 295 5.3E-93 T 05-07-2017 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 K08M4_RS03390 b5b95a78e15daf9dd021989104778025 321 Pfam PF00482 Type II secretion system (T2SS), protein F 154 276 2.9E-17 T 05-07-2017 IPR018076 Type II secretion system F domain K08M4_RS01910 6bdef96e3922a3ab67d04f5f945dffab 138 Hamap MF_01888 Regulator of ribonuclease activity B [rraB]. 11 124 28.703 T 05-07-2017 IPR016716 Regulator of ribonuclease activity B K08M4_RS01910 6bdef96e3922a3ab67d04f5f945dffab 138 Pfam PF06877 Regulator of ribonuclease activity B 20 120 4.0E-32 T 05-07-2017 IPR009671 Regulator of ribonuclease activity B domain K08M4_RS01910 6bdef96e3922a3ab67d04f5f945dffab 138 Gene3D G3DSA:3.30.70.970 9 127 3.6E-49 T 05-07-2017 IPR009671 Regulator of ribonuclease activity B domain K08M4_RS01910 6bdef96e3922a3ab67d04f5f945dffab 138 PIRSF PIRSF018193 8 138 1.8E-57 T 05-07-2017 IPR016716 Regulator of ribonuclease activity B K08M4_RS01910 6bdef96e3922a3ab67d04f5f945dffab 138 SUPERFAMILY SSF89946 9 126 9.02E-39 T 05-07-2017 IPR009671 Regulator of ribonuclease activity B domain K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 Pfam PF03949 Malic enzyme, NAD binding domain 268 528 2.7E-104 T 05-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 Hamap MF_01619 NAD-dependent malic enzyme [maeA]. 1 562 72.213 T 05-07-2017 IPR023667 NAD-dependent malic enzyme, proteobacteria GO:0004471|GO:0055114 KEGG: 00620+1.1.1.38 K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 PIRSF PIRSF000106 2 560 6.1E-225 T 05-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 Gene3D G3DSA:3.40.50.720 266 559 1.1E-109 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 PRINTS PR00072 Malic enzyme signature 144 173 7.3E-73 T 05-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 PRINTS PR00072 Malic enzyme signature 405 421 7.3E-73 T 05-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 PRINTS PR00072 Malic enzyme signature 264 280 7.3E-73 T 05-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 PRINTS PR00072 Malic enzyme signature 84 108 7.3E-73 T 05-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 PRINTS PR00072 Malic enzyme signature 295 311 7.3E-73 T 05-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 PRINTS PR00072 Malic enzyme signature 180 202 7.3E-73 T 05-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 PRINTS PR00072 Malic enzyme signature 239 257 7.3E-73 T 05-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 SMART SM00919 268 528 4.0E-133 T 05-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 SMART SM01274 78 258 2.9E-106 T 05-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 SUPERFAMILY SSF53223 4 267 6.4E-109 T 05-07-2017 K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 Gene3D G3DSA:3.40.50.10380 14 265 1.3E-114 T 05-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 SUPERFAMILY SSF51735 268 559 4.84E-95 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 ProSitePatterns PS00331 Malic enzymes signature. 264 280 - T 05-07-2017 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 K08M4_RS05970 d75cc45c0b619382fc5ea59a8382e058 562 Pfam PF00390 Malic enzyme, N-terminal domain 78 258 7.9E-78 T 05-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 K08M4_RS05015 2298be8328240f7b99b40531902ab993 180 Gene3D G3DSA:3.30.700.10 8 59 3.7E-8 T 05-07-2017 K08M4_RS05015 2298be8328240f7b99b40531902ab993 180 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 27 1.0E-6 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS05015 2298be8328240f7b99b40531902ab993 180 SUPERFAMILY SSF54523 8 97 5.41E-16 T 05-07-2017 K08M4_RS05015 2298be8328240f7b99b40531902ab993 180 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 25 1.4E-4 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SUPERFAMILY SSF53850 21 245 1.38E-15 T 05-07-2017 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SMART SM00448 1173 1289 3.5E-30 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Pfam PF01627 Hpt domain 1336 1414 1.1E-9 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SMART SM00062 274 496 0.001 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SMART SM00062 26 246 3.7E-4 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Pfam PF13188 PAS domain 551 590 1.5E-5 T 05-07-2017 IPR000014 PAS domain K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Gene3D G3DSA:3.30.450.20 686 806 7.5E-10 T 05-07-2017 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SMART SM00091 662 736 280.0 T 05-07-2017 IPR000014 PAS domain K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SMART SM00091 550 613 0.0062 T 05-07-2017 IPR000014 PAS domain K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SUPERFAMILY SSF53850 277 497 8.39E-20 T 05-07-2017 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SMART SM00387 912 1028 2.4E-38 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Gene3D G3DSA:3.30.450.20 537 586 1.1E-7 T 05-07-2017 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SUPERFAMILY SSF52172 1172 1294 2.56E-33 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Gene3D G3DSA:1.20.120.160 1311 1418 8.8E-17 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Gene3D G3DSA:3.30.565.10 866 1031 6.7E-43 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Gene3D G3DSA:1.10.287.130 807 861 6.3E-14 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SUPERFAMILY SSF55874 854 1028 5.37E-44 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 277 494 4.9E-14 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 27 244 1.1E-11 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Pfam PF00512 His Kinase A (phospho-acceptor) domain 800 865 9.0E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Gene3D G3DSA:3.40.50.2300 1171 1295 1.0E-38 T 05-07-2017 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SUPERFAMILY SSF47226 1272 1285 1.57E-19 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SUPERFAMILY SSF47226 1317 1415 1.57E-19 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Pfam PF00072 Response regulator receiver domain 1175 1284 2.3E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Gene3D G3DSA:3.40.190.10 275 359 9.8E-7 T 05-07-2017 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Gene3D G3DSA:3.40.190.10 456 495 9.8E-7 T 05-07-2017 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Gene3D G3DSA:3.40.190.10 204 244 2.7E-6 T 05-07-2017 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Gene3D G3DSA:3.40.190.10 23 111 2.7E-6 T 05-07-2017 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SUPERFAMILY SSF55785 535 646 1.35E-8 T 05-07-2017 IPR000014 PAS domain K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SUPERFAMILY SSF55785 689 789 7.53E-6 T 05-07-2017 IPR000014 PAS domain K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 913 1027 7.4E-25 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SMART SM00388 800 865 9.2E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 971 981 1.1E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 988 1006 1.1E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1012 1025 1.1E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 953 967 1.1E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS05770 5f26bb93f8ca9fee5d7f38f436e04b41 1430 SUPERFAMILY SSF47384 785 866 1.63E-18 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS14935 7294931bd83105a5d2e45ffc9c03c8f7 85 Pfam PF00137 ATP synthase subunit C 10 72 2.8E-10 T 05-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 K08M4_RS14935 7294931bd83105a5d2e45ffc9c03c8f7 85 Gene3D G3DSA:1.20.20.10 2 78 1.6E-32 T 05-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 K08M4_RS14935 7294931bd83105a5d2e45ffc9c03c8f7 85 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 20 76 1.7E-30 T 05-07-2017 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 K08M4_RS14935 7294931bd83105a5d2e45ffc9c03c8f7 85 ProSitePatterns PS00605 ATP synthase c subunit signature. 39 60 - T 05-07-2017 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 K08M4_RS14935 7294931bd83105a5d2e45ffc9c03c8f7 85 SUPERFAMILY SSF81333 3 78 1.83E-19 T 05-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 K08M4_RS14935 7294931bd83105a5d2e45ffc9c03c8f7 85 Hamap MF_01396 ATP synthase subunit c [atpH]. 8 76 14.114 T 05-07-2017 K08M4_RS14935 7294931bd83105a5d2e45ffc9c03c8f7 85 PRINTS PR00124 ATP synthase C subunit signature 49 74 1.8E-6 T 05-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 K08M4_RS14935 7294931bd83105a5d2e45ffc9c03c8f7 85 PRINTS PR00124 ATP synthase C subunit signature 11 30 1.8E-6 T 05-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 K08M4_RS14935 7294931bd83105a5d2e45ffc9c03c8f7 85 PRINTS PR00124 ATP synthase C subunit signature 32 47 1.8E-6 T 05-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 SUPERFAMILY SSF52540 369 416 8.31E-84 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 SUPERFAMILY SSF52540 5 228 8.31E-84 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 Gene3D G3DSA:3.90.1440.10 230 369 2.3E-46 T 05-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 SUPERFAMILY SSF81886 620 840 1.31E-82 T 05-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 SUPERFAMILY SSF81886 884 896 1.31E-82 T 05-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 832 19.906 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 PRINTS PR00906 SecA protein signature 101 115 2.3E-71 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 PRINTS PR00906 SecA protein signature 170 190 2.3E-71 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 PRINTS PR00906 SecA protein signature 340 362 2.3E-71 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 PRINTS PR00906 SecA protein signature 414 427 2.3E-71 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 PRINTS PR00906 SecA protein signature 377 394 2.3E-71 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 PRINTS PR00906 SecA protein signature 117 127 2.3E-71 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 PRINTS PR00906 SecA protein signature 63 87 2.3E-71 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 SMART SM00957 6 403 0.0 T 05-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 ProSitePatterns PS01312 SecA family signature. 501 516 - T 05-07-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 Pfam PF01043 SecA preprotein cross-linking domain 232 359 2.1E-38 T 05-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 816 0.0 T 05-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 Pfam PF02810 SEC-C motif 888 906 2.9E-10 T 05-07-2017 IPR004027 SEC-C motif K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 Gene3D G3DSA:3.40.50.300 370 417 8.8E-125 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 Gene3D G3DSA:3.40.50.300 2 228 8.8E-125 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 Gene3D G3DSA:1.10.3060.10 648 831 3.7E-58 T 05-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 SUPERFAMILY SSF52540 418 610 5.16E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 Gene3D G3DSA:3.40.50.300 418 619 4.5E-87 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 SUPERFAMILY SSF81767 227 369 1.44E-42 T 05-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 SMART SM00958 228 359 7.3E-81 T 05-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 Pfam PF07516 SecA Wing and Scaffold domain 617 829 6.5E-66 T 05-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 K08M4_RS12535 28b2254ede0f3c09a1047626aba23054 908 Pfam PF07517 SecA DEAD-like domain 7 403 9.8E-133 T 05-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 K08M4_RS12025 df10196698cef159bdd9fc4553554311 503 Gene3D G3DSA:3.30.420.150 132 308 7.9E-50 T 05-07-2017 K08M4_RS12025 df10196698cef159bdd9fc4553554311 503 Gene3D G3DSA:1.10.3210.10 328 414 1.4E-4 T 05-07-2017 IPR006674 HD domain K08M4_RS12025 df10196698cef159bdd9fc4553554311 503 SUPERFAMILY SSF109604 312 502 8.07E-48 T 05-07-2017 K08M4_RS12025 df10196698cef159bdd9fc4553554311 503 PIRSF PIRSF001267 4 503 4.0E-189 T 05-07-2017 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 K08M4_RS12025 df10196698cef159bdd9fc4553554311 503 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 12 305 2.1E-97 T 05-07-2017 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 K08M4_RS12025 df10196698cef159bdd9fc4553554311 503 Gene3D G3DSA:3.30.420.40 7 131 1.2E-44 T 05-07-2017 K08M4_RS12025 df10196698cef159bdd9fc4553554311 503 SUPERFAMILY SSF53067 12 131 8.35E-38 T 05-07-2017 K08M4_RS12025 df10196698cef159bdd9fc4553554311 503 SUPERFAMILY SSF53067 136 308 1.24E-44 T 05-07-2017 K08M4_RS12025 df10196698cef159bdd9fc4553554311 503 Pfam PF02541 Ppx/GppA phosphatase family 25 307 6.6E-87 T 05-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 K08M4_RS04535 9be3b9ef78330d343df502e5acd4bd76 377 Hamap MF_01825 Erythronate-4-phosphate dehydrogenase [pdxB]. 1 358 45.696 T 05-07-2017 IPR020921 Erythronate-4-phosphate dehydrogenase GO:0005737|GO:0008615|GO:0033711|GO:0055114 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181 K08M4_RS04535 9be3b9ef78330d343df502e5acd4bd76 377 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 198 214 - T 05-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site K08M4_RS04535 9be3b9ef78330d343df502e5acd4bd76 377 Gene3D G3DSA:3.40.50.720 116 259 1.9E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04535 9be3b9ef78330d343df502e5acd4bd76 377 Gene3D G3DSA:3.40.50.720 1 115 1.2E-32 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04535 9be3b9ef78330d343df502e5acd4bd76 377 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 283 6.1E-24 T 05-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 K08M4_RS04535 9be3b9ef78330d343df502e5acd4bd76 377 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 257 2.8E-35 T 05-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 K08M4_RS04535 9be3b9ef78330d343df502e5acd4bd76 377 SUPERFAMILY SSF51735 93 257 5.83E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04535 9be3b9ef78330d343df502e5acd4bd76 377 SUPERFAMILY SSF52283 3 132 8.93E-23 T 05-07-2017 K08M4_RS04535 9be3b9ef78330d343df502e5acd4bd76 377 Pfam PF11890 Domain of unknown function (DUF3410) 290 370 4.5E-29 T 05-07-2017 IPR024531 Erythronate-4-phosphate dehydrogenase, dimerisation domain GO:0046983 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181 K08M4_RS01415 73928ac25d19292a42b3bf231d7874bf 258 SUPERFAMILY SSF54534 43 249 9.82E-65 T 05-07-2017 K08M4_RS01415 73928ac25d19292a42b3bf231d7874bf 258 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 161 247 9.8E-31 T 05-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 K08M4_RS01415 73928ac25d19292a42b3bf231d7874bf 258 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 36 153 5.3E-34 T 05-07-2017 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 K08M4_RS01415 73928ac25d19292a42b3bf231d7874bf 258 Gene3D G3DSA:3.10.50.40 137 250 1.0E-47 T 05-07-2017 K08M4_RS01415 73928ac25d19292a42b3bf231d7874bf 258 Gene3D G3DSA:1.10.287.460 36 136 1.3E-36 T 05-07-2017 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 K08M4_RS10445 bc30875cecaf46f92310299715e708fb 682 TIGRFAM TIGR02816 pfaB_fam: PfaB family protein 156 655 1.2E-245 T 05-07-2017 IPR014181 Omega-3 polyunsaturated fatty acid synthase-like K08M4_RS10445 bc30875cecaf46f92310299715e708fb 682 SUPERFAMILY SSF52151 511 613 2.2E-28 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 K08M4_RS10445 bc30875cecaf46f92310299715e708fb 682 SUPERFAMILY SSF52151 311 434 2.2E-28 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 K08M4_RS10445 bc30875cecaf46f92310299715e708fb 682 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 314 627 1.3E-4 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain K08M4_RS10445 bc30875cecaf46f92310299715e708fb 682 Gene3D G3DSA:3.40.366.10 510 640 1.5E-19 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 K08M4_RS10445 bc30875cecaf46f92310299715e708fb 682 Gene3D G3DSA:3.40.366.10 306 429 1.5E-19 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 K08M4_RS11085 3a8dfa3b221cffcf5fa4659b6ecd3608 821 SUPERFAMILY SSF47203 361 508 1.53E-23 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 K08M4_RS11085 3a8dfa3b221cffcf5fa4659b6ecd3608 821 Gene3D G3DSA:2.40.110.10 238 348 5.8E-16 T 05-07-2017 K08M4_RS11085 3a8dfa3b221cffcf5fa4659b6ecd3608 821 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 361 508 3.7E-15 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 K08M4_RS11085 3a8dfa3b221cffcf5fa4659b6ecd3608 821 Gene3D G3DSA:1.20.140.10 349 508 6.0E-25 T 05-07-2017 K08M4_RS11085 3a8dfa3b221cffcf5fa4659b6ecd3608 821 SUPERFAMILY SSF56645 122 356 7.2E-43 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 K08M4_RS11085 3a8dfa3b221cffcf5fa4659b6ecd3608 821 Gene3D G3DSA:1.10.540.10 96 235 2.3E-29 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 K08M4_RS11085 3a8dfa3b221cffcf5fa4659b6ecd3608 821 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 123 234 1.0E-16 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 K08M4_RS11085 3a8dfa3b221cffcf5fa4659b6ecd3608 821 Pfam PF09317 Domain of unknown function (DUF1974) 515 801 3.4E-113 T 05-07-2017 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 K08M4_RS13875 86e8b5a235fa308b85b6516015fe12bf 144 SUPERFAMILY SSF52821 16 142 8.91E-31 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS13875 86e8b5a235fa308b85b6516015fe12bf 144 Gene3D G3DSA:3.40.250.10 22 143 1.9E-29 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS13875 86e8b5a235fa308b85b6516015fe12bf 144 SMART SM00450 40 138 2.1E-22 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS13875 86e8b5a235fa308b85b6516015fe12bf 144 Pfam PF00581 Rhodanese-like domain 43 135 5.1E-19 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 SUPERFAMILY SSF48108 396 554 1.7E-52 T 05-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 SUPERFAMILY SSF56059 673 932 6.19E-102 T 05-07-2017 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 673 874 1.1E-35 T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 8.2E-73 T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 SUPERFAMILY SSF56059 128 401 9.37E-109 T 05-07-2017 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 427 547 3.8E-40 T 05-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 SUPERFAMILY SSF52440 1 127 7.91E-51 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 Gene3D G3DSA:3.40.50.20 3 108 4.6E-46 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 838 845 - T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1052 0.0 T 05-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 709 723 - T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 SMART SM01096 424 547 3.4E-74 T 05-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 Gene3D G3DSA:3.30.1490.20 142 199 2.6E-25 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 Gene3D G3DSA:1.10.1030.10 400 538 5.6E-52 T 05-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 1.6E-64 T 05-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.6E-64 T 05-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 1.6E-64 T 05-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.6E-64 T 05-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.6E-64 T 05-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.6E-64 T 05-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.6E-64 T 05-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 05-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 SMART SM00851 955 1041 1.1E-25 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 SUPERFAMILY SSF52440 556 675 1.04E-49 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 SUPERFAMILY SSF52335 936 1071 2.09E-34 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 Gene3D G3DSA:3.30.1490.20 688 744 1.3E-25 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1067 13.339 T 05-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 Pfam PF02142 MGS-like domain 956 1041 9.0E-16 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 Gene3D G3DSA:3.40.50.1380 939 1071 5.3E-39 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 Gene3D G3DSA:3.40.50.20 539 662 3.8E-61 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1062 13.051 T 05-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 Gene3D G3DSA:3.30.470.20 200 399 1.4E-74 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS12515 8800afbcf42434bbece4278e844125a8 1076 Gene3D G3DSA:3.30.470.20 745 932 6.4E-79 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS02960 31045d6efb407d75761653f4d62cafd2 801 Gene3D G3DSA:2.70.98.40 1 325 2.0E-101 T 05-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 K08M4_RS02960 31045d6efb407d75761653f4d62cafd2 801 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 296 728 3.3E-210 T 05-07-2017 IPR033432 Glycosyl hydrolase 36, catalytic domain K08M4_RS02960 31045d6efb407d75761653f4d62cafd2 801 Gene3D G3DSA:1.50.10.10 509 675 1.5E-6 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 K08M4_RS02960 31045d6efb407d75761653f4d62cafd2 801 SMART SM01068 1 63 3.9E-20 T 05-07-2017 IPR009342 Putative carbohydrate binding domain K08M4_RS02960 31045d6efb407d75761653f4d62cafd2 801 Pfam PF06165 Glycosyltransferase family 36 21 267 1.6E-84 T 05-07-2017 IPR010383 Glycosyl hydrolase 94 K08M4_RS02960 31045d6efb407d75761653f4d62cafd2 801 Gene3D G3DSA:2.60.420.10 721 782 3.5E-10 T 05-07-2017 K08M4_RS02960 31045d6efb407d75761653f4d62cafd2 801 SUPERFAMILY SSF48208 273 800 5.1E-110 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 K08M4_RS02960 31045d6efb407d75761653f4d62cafd2 801 SUPERFAMILY SSF74650 1 269 2.35E-81 T 05-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 K08M4_RS04155 c3210eb8fb5ee06329bcc8a368b9e791 580 Pfam PF08345 Flagellar M-ring protein C-terminal 282 452 1.1E-38 T 05-07-2017 IPR013556 Flagellar M-ring C-terminal K08M4_RS04155 c3210eb8fb5ee06329bcc8a368b9e791 580 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 54 578 5.9E-73 T 05-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 K08M4_RS04155 c3210eb8fb5ee06329bcc8a368b9e791 580 PIRSF PIRSF004862 28 580 1.8E-158 T 05-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 K08M4_RS04155 c3210eb8fb5ee06329bcc8a368b9e791 580 PRINTS PR01009 Flagellar M-ring protein signature 182 196 1.1E-21 T 05-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 K08M4_RS04155 c3210eb8fb5ee06329bcc8a368b9e791 580 PRINTS PR01009 Flagellar M-ring protein signature 225 243 1.1E-21 T 05-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 K08M4_RS04155 c3210eb8fb5ee06329bcc8a368b9e791 580 PRINTS PR01009 Flagellar M-ring protein signature 375 399 1.1E-21 T 05-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 K08M4_RS04155 c3210eb8fb5ee06329bcc8a368b9e791 580 PRINTS PR01009 Flagellar M-ring protein signature 150 168 1.1E-21 T 05-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 K08M4_RS04155 c3210eb8fb5ee06329bcc8a368b9e791 580 PRINTS PR01009 Flagellar M-ring protein signature 295 313 1.1E-21 T 05-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 K08M4_RS04155 c3210eb8fb5ee06329bcc8a368b9e791 580 Pfam PF01514 Secretory protein of YscJ/FliF family 63 249 7.9E-55 T 05-07-2017 IPR006182 Secretory protein YscJ/FliF K08M4_RS10170 652ffa2c0d92aa4f62987cb28ea3d78c 261 Gene3D G3DSA:3.30.420.10 92 238 4.6E-38 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS10170 652ffa2c0d92aa4f62987cb28ea3d78c 261 SUPERFAMILY SSF53098 93 236 2.28E-37 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS10170 652ffa2c0d92aa4f62987cb28ea3d78c 261 Pfam PF01693 Caulimovirus viroplasmin 4 46 1.8E-21 T 05-07-2017 IPR011320 Ribonuclease H1, N-terminal K08M4_RS10170 652ffa2c0d92aa4f62987cb28ea3d78c 261 Gene3D G3DSA:3.40.970.10 2 50 6.4E-25 T 05-07-2017 IPR011320 Ribonuclease H1, N-terminal K08M4_RS10170 652ffa2c0d92aa4f62987cb28ea3d78c 261 SUPERFAMILY SSF55658 3 47 1.57E-15 T 05-07-2017 IPR009027 Ribosomal protein L9/RNase H1, N-terminal K08M4_RS10170 652ffa2c0d92aa4f62987cb28ea3d78c 261 Pfam PF00075 RNase H 93 232 1.2E-28 T 05-07-2017 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 K08M4_RS01250 e5bad6e1cf4900b43a6fde53dad2fa14 838 Pfam PF00912 Transglycosylase 41 215 2.4E-63 T 05-07-2017 IPR001264 Glycosyl transferase, family 51 K08M4_RS01250 e5bad6e1cf4900b43a6fde53dad2fa14 838 Pfam PF00905 Penicillin binding protein transpeptidase domain 435 716 4.8E-28 T 05-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 K08M4_RS01250 e5bad6e1cf4900b43a6fde53dad2fa14 838 Gene3D G3DSA:3.40.710.10 429 817 7.5E-127 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS01250 e5bad6e1cf4900b43a6fde53dad2fa14 838 Gene3D G3DSA:3.40.710.10 218 299 7.5E-127 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS01250 e5bad6e1cf4900b43a6fde53dad2fa14 838 SUPERFAMILY SSF53955 29 241 2.81E-77 T 05-07-2017 IPR023346 Lysozyme-like domain K08M4_RS01250 e5bad6e1cf4900b43a6fde53dad2fa14 838 SUPERFAMILY SSF56601 197 219 3.09E-114 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS01250 e5bad6e1cf4900b43a6fde53dad2fa14 838 SUPERFAMILY SSF56601 649 818 3.09E-114 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS01250 e5bad6e1cf4900b43a6fde53dad2fa14 838 SUPERFAMILY SSF56601 248 299 3.09E-114 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS01250 e5bad6e1cf4900b43a6fde53dad2fa14 838 SUPERFAMILY SSF56601 429 617 3.09E-114 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS01250 e5bad6e1cf4900b43a6fde53dad2fa14 838 Pfam PF17092 Penicillin-binding protein OB-like domain 302 432 5.6E-31 T 05-07-2017 IPR031376 Penicillin-binding protein, OB-like domain K08M4_RS01250 e5bad6e1cf4900b43a6fde53dad2fa14 838 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 51 765 1.1E-166 T 05-07-2017 K08M4_RS01250 e5bad6e1cf4900b43a6fde53dad2fa14 838 Gene3D G3DSA:2.40.50.140 333 428 4.2E-18 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS01250 e5bad6e1cf4900b43a6fde53dad2fa14 838 Gene3D G3DSA:1.10.3810.10 41 217 7.5E-74 T 05-07-2017 K08M4_RS14940 03d7aa4e8ae079318e1a95df8fc57e67 265 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 30 258 1.0E-45 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 K08M4_RS14940 03d7aa4e8ae079318e1a95df8fc57e67 265 SUPERFAMILY SSF81336 88 257 2.88E-50 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 K08M4_RS14940 03d7aa4e8ae079318e1a95df8fc57e67 265 Gene3D G3DSA:1.20.120.220 89 262 1.1E-60 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 K08M4_RS14940 03d7aa4e8ae079318e1a95df8fc57e67 265 ProSitePatterns PS00449 ATP synthase a subunit signature. 198 207 - T 05-07-2017 IPR023011 ATPase, F0 complex, subunit A, active site Reactome: R-HSA-163210 K08M4_RS14940 03d7aa4e8ae079318e1a95df8fc57e67 265 Hamap MF_01393 ATP synthase subunit a [atpB]. 10 263 15.894 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 K08M4_RS14940 03d7aa4e8ae079318e1a95df8fc57e67 265 Pfam PF00119 ATP synthase A chain 39 257 4.7E-59 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 K08M4_RS14940 03d7aa4e8ae079318e1a95df8fc57e67 265 PRINTS PR00123 ATP synthase A subunit signature 195 217 5.4E-15 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 K08M4_RS14940 03d7aa4e8ae079318e1a95df8fc57e67 265 PRINTS PR00123 ATP synthase A subunit signature 243 258 5.4E-15 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 K08M4_RS14940 03d7aa4e8ae079318e1a95df8fc57e67 265 PRINTS PR00123 ATP synthase A subunit signature 96 112 5.4E-15 T 05-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 K08M4_RS01055 0451e060cc01cb802413630773434113 205 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 163 170 - T 05-07-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS01055 0451e060cc01cb802413630773434113 205 Gene3D G3DSA:1.10.287.990 20 85 1.1E-22 T 05-07-2017 K08M4_RS01055 0451e060cc01cb802413630773434113 205 PRINTS PR01703 Manganese superoxide dismutase signature 161 173 2.8E-22 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS01055 0451e060cc01cb802413630773434113 205 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.8E-22 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS01055 0451e060cc01cb802413630773434113 205 PRINTS PR01703 Manganese superoxide dismutase signature 68 81 2.8E-22 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS01055 0451e060cc01cb802413630773434113 205 PRINTS PR01703 Manganese superoxide dismutase signature 121 129 2.8E-22 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS01055 0451e060cc01cb802413630773434113 205 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 2.8E-22 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS01055 0451e060cc01cb802413630773434113 205 SUPERFAMILY SSF54719 87 201 1.96E-43 T 05-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS01055 0451e060cc01cb802413630773434113 205 PIRSF PIRSF000349 1 205 5.3E-79 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS01055 0451e060cc01cb802413630773434113 205 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 92 195 1.0E-39 T 05-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS01055 0451e060cc01cb802413630773434113 205 SUPERFAMILY SSF46609 1 85 3.01E-29 T 05-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS01055 0451e060cc01cb802413630773434113 205 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 85 2.2E-27 T 05-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS00270 d622545874c01a3bd2e6a4b33dc6ef3f 223 Pfam PF02592 Putative vitamin uptake transporter 43 199 5.6E-38 T 05-07-2017 IPR003744 Protein of unknown function DUF165 K08M4_RS00270 d622545874c01a3bd2e6a4b33dc6ef3f 223 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 13 204 4.2E-63 T 05-07-2017 IPR003744 Protein of unknown function DUF165 K08M4_RS18830 0b795374713cfdac4cd32e04b5eedd2a 483 Pfam PF01226 Formate/nitrite transporter 17 277 5.8E-71 T 05-07-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 K08M4_RS18830 0b795374713cfdac4cd32e04b5eedd2a 483 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 85 94 - T 05-07-2017 IPR024002 Formate/nitrite transporter, conserved site K08M4_RS18830 0b795374713cfdac4cd32e04b5eedd2a 483 Gene3D G3DSA:3.20.20.70 309 402 1.8E-19 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS18830 0b795374713cfdac4cd32e04b5eedd2a 483 Gene3D G3DSA:3.20.20.70 434 466 1.8E-19 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS18830 0b795374713cfdac4cd32e04b5eedd2a 483 SMART SM00116 418 465 20.0 T 05-07-2017 IPR000644 CBS domain K08M4_RS18830 0b795374713cfdac4cd32e04b5eedd2a 483 SMART SM00116 320 368 0.37 T 05-07-2017 IPR000644 CBS domain K08M4_RS18830 0b795374713cfdac4cd32e04b5eedd2a 483 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 170 180 - T 05-07-2017 IPR024002 Formate/nitrite transporter, conserved site K08M4_RS18830 0b795374713cfdac4cd32e04b5eedd2a 483 Pfam PF00571 CBS domain 382 464 0.0013 T 05-07-2017 IPR000644 CBS domain K08M4_RS18830 0b795374713cfdac4cd32e04b5eedd2a 483 Pfam PF00571 CBS domain 313 364 3.0E-6 T 05-07-2017 IPR000644 CBS domain K08M4_RS18830 0b795374713cfdac4cd32e04b5eedd2a 483 SUPERFAMILY SSF54631 309 398 6.96E-19 T 05-07-2017 K08M4_RS18830 0b795374713cfdac4cd32e04b5eedd2a 483 SUPERFAMILY SSF54631 430 464 6.96E-19 T 05-07-2017 K08M4_RS18830 0b795374713cfdac4cd32e04b5eedd2a 483 Gene3D G3DSA:1.20.1080.10 33 282 7.3E-84 T 05-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 K08M4_RS18830 0b795374713cfdac4cd32e04b5eedd2a 483 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 28 281 2.5E-74 T 05-07-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 K08M4_RS18830 0b795374713cfdac4cd32e04b5eedd2a 483 TIGRFAM TIGR04060 formate_focA: formate transporter FocA 16 281 3.2E-113 T 05-07-2017 IPR023999 Formate transporter FocA, putative GO:0015499|GO:0015724|GO:0016021 K08M4_RS05905 6441832d6793e760f5fdfd6b821012c5 573 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 6 533 1.9E-134 T 05-07-2017 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 K08M4_RS05905 6441832d6793e760f5fdfd6b821012c5 573 SMART SM00382 365 549 3.1E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS05905 6441832d6793e760f5fdfd6b821012c5 573 SUPERFAMILY SSF52540 335 571 1.71E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05905 6441832d6793e760f5fdfd6b821012c5 573 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS05905 6441832d6793e760f5fdfd6b821012c5 573 Pfam PF00005 ABC transporter 356 502 8.0E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS05905 6441832d6793e760f5fdfd6b821012c5 573 SUPERFAMILY SSF90123 7 313 9.94E-37 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS05905 6441832d6793e760f5fdfd6b821012c5 573 Gene3D G3DSA:3.40.50.300 339 568 8.1E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05905 6441832d6793e760f5fdfd6b821012c5 573 Pfam PF00664 ABC transporter transmembrane region 80 286 5.5E-8 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS05905 6441832d6793e760f5fdfd6b821012c5 573 Gene3D G3DSA:1.20.1560.10 4 322 1.3E-26 T 05-07-2017 K08M4_RS20850 16c9ffcb8ecf3cd2a913ab61369363e0 346 SUPERFAMILY SSF53850 56 306 6.11E-45 T 05-07-2017 K08M4_RS20850 16c9ffcb8ecf3cd2a913ab61369363e0 346 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 61 296 2.1E-56 T 05-07-2017 K08M4_RS20850 16c9ffcb8ecf3cd2a913ab61369363e0 346 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 44 275 2.3E-57 T 05-07-2017 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 K08M4_RS20850 16c9ffcb8ecf3cd2a913ab61369363e0 346 Gene3D G3DSA:3.40.190.10 150 266 2.5E-16 T 05-07-2017 K08M4_RS20490 696374b3000f9f35384b7102f44a23a5 301 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 3 286 3.4E-84 T 05-07-2017 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 K08M4_RS20490 696374b3000f9f35384b7102f44a23a5 301 Gene3D G3DSA:3.30.1490.20 103 172 7.0E-7 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 K08M4_RS20490 696374b3000f9f35384b7102f44a23a5 301 SUPERFAMILY SSF56059 89 290 2.65E-50 T 05-07-2017 K08M4_RS20490 696374b3000f9f35384b7102f44a23a5 301 Pfam PF08443 RimK-like ATP-grasp domain 98 286 3.5E-68 T 05-07-2017 IPR013651 ATP-grasp fold, RimK-type K08M4_RS20490 696374b3000f9f35384b7102f44a23a5 301 Gene3D G3DSA:3.30.470.20 173 276 1.4E-36 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS20490 696374b3000f9f35384b7102f44a23a5 301 Gene3D G3DSA:3.40.50.20 8 102 2.1E-17 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS20490 696374b3000f9f35384b7102f44a23a5 301 Hamap MF_01552 Ribosomal protein S6--L-glutamate ligase [rimK]. 1 295 51.976 T 05-07-2017 IPR023533 Ribosomal protein S6--L-glutamate ligase RimK K08M4_RS08260 c26633743f8dc35fa08baf97ebce59bc 308 SUPERFAMILY SSF53474 143 293 2.25E-9 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS08260 c26633743f8dc35fa08baf97ebce59bc 308 Gene3D G3DSA:3.40.50.1820 143 251 6.1E-5 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS10775 6bced30ef14bd69c335850553afccc12 29 Pfam PF11665 Protein of unknown function (DUF3265) 2 29 5.5E-15 T 05-07-2017 IPR021681 Protein of unknown function DUF3265 K08M4_RS10890 d28011d696f4e3fe11a90d0612faf20d 378 SUPERFAMILY SSF64383 241 373 1.31E-44 T 05-07-2017 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 K08M4_RS10890 d28011d696f4e3fe11a90d0612faf20d 378 SMART SM00771 239 369 5.4E-59 T 05-07-2017 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 K08M4_RS10890 d28011d696f4e3fe11a90d0612faf20d 378 Gene3D G3DSA:3.30.1400.10 241 373 4.8E-52 T 05-07-2017 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 K08M4_RS10890 d28011d696f4e3fe11a90d0612faf20d 378 TIGRFAM TIGR02205 septum_zipA: cell division protein ZipA 3 369 2.4E-76 T 05-07-2017 IPR011919 Cell division protein ZipA GO:0000917|GO:0007049|GO:0016021 K08M4_RS10890 d28011d696f4e3fe11a90d0612faf20d 378 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 242 368 4.2E-42 T 05-07-2017 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 K08M4_RS10890 d28011d696f4e3fe11a90d0612faf20d 378 Hamap MF_00509 Cell division protein ZipA [zipA]. 2 371 21.3 T 05-07-2017 IPR011919 Cell division protein ZipA GO:0000917|GO:0007049|GO:0016021 K08M4_RS10890 d28011d696f4e3fe11a90d0612faf20d 378 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 242 378 1.0E-54 T 05-07-2017 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 K08M4_RS15475 225bdb97797e50bc407f8187b704879c 188 Gene3D G3DSA:3.40.430.10 15 186 5.2E-32 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 K08M4_RS15475 225bdb97797e50bc407f8187b704879c 188 Pfam PF01872 RibD C-terminal domain 15 179 4.9E-16 T 05-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 K08M4_RS15475 225bdb97797e50bc407f8187b704879c 188 SUPERFAMILY SSF53597 15 186 5.63E-34 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 K08M4_RS17325 31687f32558738d7ddd862046e50a9cc 711 Pfam PF16130 Domain of unknown function (DUF4842) 479 700 2.9E-57 T 05-07-2017 IPR032295 Domain of unknown function DUF4842 K08M4_RS17325 31687f32558738d7ddd862046e50a9cc 711 Gene3D G3DSA:2.120.10.30 28 236 2.3E-5 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like K08M4_RS17325 31687f32558738d7ddd862046e50a9cc 711 SUPERFAMILY SSF75011 33 287 1.31E-11 T 05-07-2017 K08M4_RS17325 31687f32558738d7ddd862046e50a9cc 711 TIGRFAM TIGR04456 LruC_dom: LruC domain 446 701 2.2E-80 T 05-07-2017 IPR031025 LruC domain K08M4_RS01885 26c1b414e10cc1dbfbbb047edd263e68 129 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 104 122 - T 05-07-2017 IPR019897 RidA, conserved site K08M4_RS01885 26c1b414e10cc1dbfbbb047edd263e68 129 SUPERFAMILY SSF55298 2 128 7.7E-44 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS01885 26c1b414e10cc1dbfbbb047edd263e68 129 Gene3D G3DSA:3.30.1330.40 5 128 5.3E-47 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS01885 26c1b414e10cc1dbfbbb047edd263e68 129 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 127 3.7E-53 T 05-07-2017 IPR006056 RidA family K08M4_RS01885 26c1b414e10cc1dbfbbb047edd263e68 129 Pfam PF01042 Endoribonuclease L-PSP 8 127 2.0E-44 T 05-07-2017 IPR006175 YjgF/YER057c/UK114 family K08M4_RS04860 95c9662f9be94832d976829a04deaf81 230 Hamap MF_00478 Electron transport complex subunit RsxE [rsxE]. 1 210 27.883 T 05-07-2017 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 K08M4_RS04860 95c9662f9be94832d976829a04deaf81 230 PIRSF PIRSF006102 1 219 3.6E-77 T 05-07-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 K08M4_RS04860 95c9662f9be94832d976829a04deaf81 230 Pfam PF02508 Rnf-Nqr subunit, membrane protein 6 200 4.2E-64 T 05-07-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 K08M4_RS04860 95c9662f9be94832d976829a04deaf81 230 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 6 208 3.9E-87 T 05-07-2017 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 K08M4_RS09205 e77b4f5cae509ecfe5cd8f55c4bc2dcf 109 Hamap MF_00680 UPF0263 protein YciU [yciU]. 4 109 35.984 T 05-07-2017 IPR007376 dsDNA mimic, putative K08M4_RS09205 e77b4f5cae509ecfe5cd8f55c4bc2dcf 109 Pfam PF04269 Protein of unknown function, DUF440 8 108 1.5E-44 T 05-07-2017 IPR007376 dsDNA mimic, putative K08M4_RS09205 e77b4f5cae509ecfe5cd8f55c4bc2dcf 109 Gene3D G3DSA:3.10.450.140 9 108 1.0E-45 T 05-07-2017 IPR007376 dsDNA mimic, putative K08M4_RS09205 e77b4f5cae509ecfe5cd8f55c4bc2dcf 109 PIRSF PIRSF004916 1 108 1.1E-52 T 05-07-2017 IPR007376 dsDNA mimic, putative K08M4_RS09205 e77b4f5cae509ecfe5cd8f55c4bc2dcf 109 SUPERFAMILY SSF102816 2 108 2.88E-49 T 05-07-2017 IPR007376 dsDNA mimic, putative K08M4_RS09205 e77b4f5cae509ecfe5cd8f55c4bc2dcf 109 ProDom PD020447 UPF0263 YCIU HD0986 VV1228 UNCHARACTERIZED 3D-STRUCTURE VV13059 BCR PM0536 VC1208 11 107 6.0E-47 T 05-07-2017 IPR007376 dsDNA mimic, putative K08M4_RS06945 75f4a1743c54a65cc5237ffb1259a1f5 294 SUPERFAMILY SSF56112 18 222 2.35E-19 T 05-07-2017 IPR011009 Protein kinase-like domain K08M4_RS06945 75f4a1743c54a65cc5237ffb1259a1f5 294 Gene3D G3DSA:1.10.510.10 139 223 2.2E-18 T 05-07-2017 K08M4_RS06945 75f4a1743c54a65cc5237ffb1259a1f5 294 Pfam PF01163 RIO1 family 31 222 8.4E-41 T 05-07-2017 K08M4_RS06945 75f4a1743c54a65cc5237ffb1259a1f5 294 Gene3D G3DSA:3.30.200.20 16 125 4.7E-12 T 05-07-2017 K08M4_RS06945 75f4a1743c54a65cc5237ffb1259a1f5 294 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 164 175 - T 05-07-2017 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|Reactome: R-HSA-6791226 K08M4_RS06945 75f4a1743c54a65cc5237ffb1259a1f5 294 SMART SM00090 5 234 2.5E-16 T 05-07-2017 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|Reactome: R-HSA-6791226 K08M4_RS09360 dc1f942f686e627a7cc9ddd2e231c9c2 333 SUPERFAMILY SSF52540 4 269 4.17E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09360 dc1f942f686e627a7cc9ddd2e231c9c2 333 SMART SM00382 32 237 4.5E-4 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS09360 dc1f942f686e627a7cc9ddd2e231c9c2 333 Pfam PF00005 ABC transporter 24 187 9.4E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS09360 dc1f942f686e627a7cc9ddd2e231c9c2 333 Gene3D G3DSA:3.40.50.300 2 260 5.4E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09360 dc1f942f686e627a7cc9ddd2e231c9c2 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 323 1.3E-19 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS09360 dc1f942f686e627a7cc9ddd2e231c9c2 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 305 3.4E-15 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS17995 d6113efd8194ddc871786015020637a8 357 Gene3D G3DSA:1.10.760.10 164 330 8.0E-38 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS17995 d6113efd8194ddc871786015020637a8 357 SUPERFAMILY SSF46626 259 327 3.57E-28 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS17995 d6113efd8194ddc871786015020637a8 357 SUPERFAMILY SSF46626 171 213 3.57E-28 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS17995 d6113efd8194ddc871786015020637a8 357 SUPERFAMILY SSF46626 20 165 2.59E-34 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS17995 d6113efd8194ddc871786015020637a8 357 Pfam PF03150 Di-haem cytochrome c peroxidase 31 172 4.2E-30 T 05-07-2017 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 K08M4_RS17995 d6113efd8194ddc871786015020637a8 357 Pfam PF00034 Cytochrome c 181 327 2.6E-4 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS17995 d6113efd8194ddc871786015020637a8 357 Gene3D G3DSA:1.10.760.10 27 163 4.8E-35 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS17995 d6113efd8194ddc871786015020637a8 357 PIRSF PIRSF000294 18 336 1.3E-58 T 05-07-2017 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 K08M4_RS02490 547083a013d0c617b60b650f82eb86f9 439 SUPERFAMILY SSF53335 77 438 4.25E-85 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS02490 547083a013d0c617b60b650f82eb86f9 439 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 421 431 - T 05-07-2017 IPR030391 RNA methyltransferase TrmA, conserved site K08M4_RS02490 547083a013d0c617b60b650f82eb86f9 439 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 98 436 2.4E-32 T 05-07-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 K08M4_RS02490 547083a013d0c617b60b650f82eb86f9 439 Gene3D G3DSA:3.40.50.150 259 436 3.6E-56 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS02490 547083a013d0c617b60b650f82eb86f9 439 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 370 400 - T 05-07-2017 IPR030390 RNA methyltransferase TrmA, active site K08M4_RS02490 547083a013d0c617b60b650f82eb86f9 439 SUPERFAMILY SSF50249 18 74 1.6E-13 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS02490 547083a013d0c617b60b650f82eb86f9 439 Pfam PF01938 TRAM domain 16 67 3.9E-12 T 05-07-2017 IPR002792 TRAM domain K08M4_RS02490 547083a013d0c617b60b650f82eb86f9 439 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 19 439 63.74 T 05-07-2017 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 K08M4_RS02490 547083a013d0c617b60b650f82eb86f9 439 Gene3D G3DSA:2.40.50.140 16 88 4.1E-26 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS02490 547083a013d0c617b60b650f82eb86f9 439 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 25 431 1.1E-129 T 05-07-2017 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 K08M4_RS02305 720075524d2024195dce9c659e4d88b7 477 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 372 472 3.7E-17 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS02305 720075524d2024195dce9c659e4d88b7 477 SMART SM00387 371 477 1.6E-24 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS02305 720075524d2024195dce9c659e4d88b7 477 SUPERFAMILY SSF55874 330 473 4.58E-30 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS02305 720075524d2024195dce9c659e4d88b7 477 Gene3D G3DSA:1.10.287.130 265 319 1.3E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS02305 720075524d2024195dce9c659e4d88b7 477 SUPERFAMILY SSF47384 258 325 2.16E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS02305 720075524d2024195dce9c659e4d88b7 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 419 1.8E-11 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS02305 720075524d2024195dce9c659e4d88b7 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 433 1.8E-11 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS02305 720075524d2024195dce9c659e4d88b7 477 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 455 1.8E-11 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS02305 720075524d2024195dce9c659e4d88b7 477 Gene3D G3DSA:3.30.565.10 338 473 8.2E-29 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS05050 8d07a0d9ec9648329fb9d6e5cafa437a 358 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 94 337 4.5E-99 T 05-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein K08M4_RS05050 8d07a0d9ec9648329fb9d6e5cafa437a 358 Gene3D G3DSA:3.40.50.300 88 337 1.5E-103 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05050 8d07a0d9ec9648329fb9d6e5cafa437a 358 ProSitePatterns PS01215 Mrp family signature. 201 217 - T 05-07-2017 IPR000808 Mrp, conserved site GO:0005524 K08M4_RS05050 8d07a0d9ec9648329fb9d6e5cafa437a 358 SUPERFAMILY SSF52540 85 319 4.26E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05050 8d07a0d9ec9648329fb9d6e5cafa437a 358 Hamap MF_02040 Iron-sulfur cluster carrier protein. 89 338 35.981 T 05-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein K08M4_RS18405 3ed236d3df1259dbff0c156f84a6cf9b 156 PIRSF PIRSF000368 1 156 4.5E-60 T 05-07-2017 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 K08M4_RS18405 3ed236d3df1259dbff0c156f84a6cf9b 156 Pfam PF13353 4Fe-4S single cluster domain 12 151 1.4E-51 T 05-07-2017 K08M4_RS18405 3ed236d3df1259dbff0c156f84a6cf9b 156 ProSitePatterns PS01087 Radical activating enzymes signature. 14 35 - T 05-07-2017 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 K08M4_RS18405 3ed236d3df1259dbff0c156f84a6cf9b 156 SUPERFAMILY SSF102114 10 120 8.89E-7 T 05-07-2017 K08M4_RS18405 3ed236d3df1259dbff0c156f84a6cf9b 156 Gene3D G3DSA:3.20.20.70 21 130 2.9E-6 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS18405 3ed236d3df1259dbff0c156f84a6cf9b 156 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 2 152 9.5E-60 T 05-07-2017 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 Gene3D G3DSA:3.20.20.10 69 333 3.3E-59 T 05-07-2017 IPR029066 PLP-binding barrel K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 SUPERFAMILY SSF51419 65 347 1.8E-64 T 05-07-2017 IPR029066 PLP-binding barrel K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 91 346 3.8E-52 T 05-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 Gene3D G3DSA:2.40.37.10 457 590 2.2E-15 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 Gene3D G3DSA:2.40.37.10 334 358 2.2E-15 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 SUPERFAMILY SSF50621 463 568 8.89E-6 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 TIGRFAM TIGR01273 speA: arginine decarboxylase 8 633 5.7E-266 T 05-07-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 PIRSF PIRSF001336 2 635 5.2E-252 T 05-07-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 350 564 6.9E-24 T 05-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 241 254 1.6E-12 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 335 354 1.6E-12 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 544 557 1.6E-12 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 97 115 1.6E-12 T 05-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 PRINTS PR01180 Arginine decarboxylase signature 148 163 7.6E-65 T 05-07-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 PRINTS PR01180 Arginine decarboxylase signature 89 103 7.6E-65 T 05-07-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 PRINTS PR01180 Arginine decarboxylase signature 198 220 7.6E-65 T 05-07-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 PRINTS PR01180 Arginine decarboxylase signature 65 80 7.6E-65 T 05-07-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 PRINTS PR01180 Arginine decarboxylase signature 491 516 7.6E-65 T 05-07-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 PRINTS PR01180 Arginine decarboxylase signature 325 342 7.6E-65 T 05-07-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 PRINTS PR01180 Arginine decarboxylase signature 174 195 7.6E-65 T 05-07-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 PRINTS PR01180 Arginine decarboxylase signature 466 487 7.6E-65 T 05-07-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 PRINTS PR01180 Arginine decarboxylase signature 544 565 7.6E-65 T 05-07-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 K08M4_RS06160 e3a92aae300d3d79a0d2b866769ed9c6 635 Hamap MF_01417 Biosynthetic arginine decarboxylase [speA]. 3 634 42.407 T 05-07-2017 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 K08M4_RS14850 01520cedf2b6f778dd1720b7e545c0e9 199 SUPERFAMILY SSF52833 22 198 2.72E-46 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS14850 01520cedf2b6f778dd1720b7e545c0e9 199 Gene3D G3DSA:3.40.30.10 119 196 9.1E-23 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS14850 01520cedf2b6f778dd1720b7e545c0e9 199 Gene3D G3DSA:3.40.30.10 2 116 8.3E-40 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS14850 01520cedf2b6f778dd1720b7e545c0e9 199 PIRSF PIRSF001488 1 199 7.6E-70 T 05-07-2017 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL K08M4_RS14850 01520cedf2b6f778dd1720b7e545c0e9 199 ProSitePatterns PS00194 Thioredoxin family active site. 41 59 - T 05-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 K08M4_RS14850 01520cedf2b6f778dd1720b7e545c0e9 199 Pfam PF01323 DSBA-like thioredoxin domain 41 189 1.6E-28 T 05-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 K08M4_RS12385 243a6af703d53dafa0e0a9bcbd1a6f90 183 Gene3D G3DSA:1.20.120.520 3 154 4.4E-16 T 05-07-2017 K08M4_RS12385 243a6af703d53dafa0e0a9bcbd1a6f90 183 Pfam PF01814 Hemerythrin HHE cation binding domain 2 135 1.3E-12 T 05-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 K08M4_RS19210 a4d5ddcf9073a50aa8160ea9d6fcad97 443 SUPERFAMILY SSF102114 24 372 1.57E-37 T 05-07-2017 K08M4_RS19210 a4d5ddcf9073a50aa8160ea9d6fcad97 443 TIGRFAM TIGR03942 sulfatase_rSAM: anaerobic sulfatase maturase 18 409 3.5E-148 T 05-07-2017 IPR023867 Anaerobic sulphatase maturase, radical SAM GO:0016491 K08M4_RS19210 a4d5ddcf9073a50aa8160ea9d6fcad97 443 Pfam PF04055 Radical SAM superfamily 24 196 3.6E-11 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS19210 a4d5ddcf9073a50aa8160ea9d6fcad97 443 Pfam PF13186 Iron-sulfur cluster-binding domain 303 363 8.0E-7 T 05-07-2017 IPR023885 4Fe4S-binding SPASM domain K08M4_RS19210 a4d5ddcf9073a50aa8160ea9d6fcad97 443 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 302 391 4.5E-18 T 05-07-2017 IPR023885 4Fe4S-binding SPASM domain K08M4_RS19210 a4d5ddcf9073a50aa8160ea9d6fcad97 443 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 195 405 2.0E-5 T 05-07-2017 K08M4_RS19210 a4d5ddcf9073a50aa8160ea9d6fcad97 443 Gene3D G3DSA:3.20.20.70 26 380 1.3E-36 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS08775 ca284796b14a9f94f80a1c8cf4541a93 439 Pfam PF14067 LssY C-terminus 246 412 1.2E-41 T 05-07-2017 IPR025902 LssY-like C-terminal domain K08M4_RS08775 ca284796b14a9f94f80a1c8cf4541a93 439 Pfam PF09335 SNARE associated Golgi protein 23 136 4.7E-15 T 05-07-2017 IPR032816 SNARE associated Golgi protein K08M4_RS08515 6726586f248d33d96545e49fd370d3c5 544 SMART SM00283 271 532 1.1E-54 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS08515 6726586f248d33d96545e49fd370d3c5 544 SUPERFAMILY SSF58104 224 535 6.67E-62 T 05-07-2017 K08M4_RS08515 6726586f248d33d96545e49fd370d3c5 544 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 326 531 1.6E-46 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS08515 6726586f248d33d96545e49fd370d3c5 544 Pfam PF00672 HAMP domain 184 250 7.3E-9 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS08515 6726586f248d33d96545e49fd370d3c5 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 369 396 1.5E-22 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS08515 6726586f248d33d96545e49fd370d3c5 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 288 317 1.5E-22 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS08515 6726586f248d33d96545e49fd370d3c5 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 398 427 1.5E-22 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS08515 6726586f248d33d96545e49fd370d3c5 544 Gene3D G3DSA:1.10.287.950 286 499 1.4E-49 T 05-07-2017 K08M4_RS08515 6726586f248d33d96545e49fd370d3c5 544 SMART SM00304 203 256 1.5E-8 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS20140 14f003ce1814af1ce85734b89a03f1fd 336 Gene3D G3DSA:3.40.190.10 97 176 4.7E-7 T 05-07-2017 K08M4_RS20140 14f003ce1814af1ce85734b89a03f1fd 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 1.0E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS20140 14f003ce1814af1ce85734b89a03f1fd 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 1.0E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS20140 14f003ce1814af1ce85734b89a03f1fd 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 1.0E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS20140 14f003ce1814af1ce85734b89a03f1fd 336 SUPERFAMILY SSF53850 95 304 3.8E-15 T 05-07-2017 K08M4_RS20140 14f003ce1814af1ce85734b89a03f1fd 336 Pfam PF03466 LysR substrate binding domain 93 306 7.4E-12 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS20140 14f003ce1814af1ce85734b89a03f1fd 336 Gene3D G3DSA:3.40.190.10 177 277 4.8E-12 T 05-07-2017 K08M4_RS20140 14f003ce1814af1ce85734b89a03f1fd 336 SUPERFAMILY SSF46785 10 88 5.46E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20140 14f003ce1814af1ce85734b89a03f1fd 336 Gene3D G3DSA:1.10.10.10 11 87 3.0E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20140 14f003ce1814af1ce85734b89a03f1fd 336 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 69 2.1E-19 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS04520 10baf5f1281dd4eb39cd65f7b71505b1 715 SUPERFAMILY SSF51905 289 509 9.06E-30 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS04520 10baf5f1281dd4eb39cd65f7b71505b1 715 SUPERFAMILY SSF51905 631 698 9.06E-30 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS04520 10baf5f1281dd4eb39cd65f7b71505b1 715 Pfam PF01266 FAD dependent oxidoreductase 289 669 8.8E-43 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 K08M4_RS04520 10baf5f1281dd4eb39cd65f7b71505b1 715 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 289 699 2.4E-141 T 05-07-2017 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 K08M4_RS04520 10baf5f1281dd4eb39cd65f7b71505b1 715 Gene3D G3DSA:3.50.50.60 602 683 1.9E-26 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS04520 10baf5f1281dd4eb39cd65f7b71505b1 715 Gene3D G3DSA:3.50.50.60 421 508 1.9E-26 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS04520 10baf5f1281dd4eb39cd65f7b71505b1 715 Gene3D G3DSA:3.50.50.60 277 367 1.9E-26 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS04520 10baf5f1281dd4eb39cd65f7b71505b1 715 Gene3D G3DSA:3.40.50.150 32 273 1.8E-101 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS04520 10baf5f1281dd4eb39cd65f7b71505b1 715 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 29 694 27.358 T 05-07-2017 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 K08M4_RS04520 10baf5f1281dd4eb39cd65f7b71505b1 715 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 140 265 1.7E-45 T 05-07-2017 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 K08M4_RS12245 e4a801f738330f347cfcbe8ed150578e 311 Pfam PF06574 FAD synthetase 11 166 6.2E-58 T 05-07-2017 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS12245 e4a801f738330f347cfcbe8ed150578e 311 SMART SM00904 183 307 9.5E-62 T 05-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 K08M4_RS12245 e4a801f738330f347cfcbe8ed150578e 311 Gene3D G3DSA:2.40.30.30 188 307 5.7E-38 T 05-07-2017 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 K08M4_RS12245 e4a801f738330f347cfcbe8ed150578e 311 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 306 1.8E-101 T 05-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS12245 e4a801f738330f347cfcbe8ed150578e 311 Pfam PF01687 Riboflavin kinase 184 306 4.9E-37 T 05-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 K08M4_RS12245 e4a801f738330f347cfcbe8ed150578e 311 SUPERFAMILY SSF52374 15 175 5.63E-36 T 05-07-2017 K08M4_RS12245 e4a801f738330f347cfcbe8ed150578e 311 PIRSF PIRSF004491 1 311 1.0E-105 T 05-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS12245 e4a801f738330f347cfcbe8ed150578e 311 SUPERFAMILY SSF82114 174 307 2.83E-43 T 05-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 K08M4_RS12245 e4a801f738330f347cfcbe8ed150578e 311 Gene3D G3DSA:3.40.50.620 1 186 6.1E-66 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS04680 4a57bbbf942103e7a63cd6024b224b6a 145 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 17 140 35.334 T 05-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS04680 4a57bbbf942103e7a63cd6024b224b6a 145 Pfam PF01641 SelR domain 21 138 1.8E-51 T 05-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS04680 4a57bbbf942103e7a63cd6024b224b6a 145 Gene3D G3DSA:2.170.150.20 14 143 1.1E-57 T 05-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS04680 4a57bbbf942103e7a63cd6024b224b6a 145 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 17 142 7.1E-54 T 05-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS04680 4a57bbbf942103e7a63cd6024b224b6a 145 SUPERFAMILY SSF51316 16 142 3.92E-55 T 05-07-2017 IPR011057 Mss4-like K08M4_RS15710 0308ed1f2392a2b3e1e100fa458af010 330 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 298 6.6E-51 T 05-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 K08M4_RS15710 0308ed1f2392a2b3e1e100fa458af010 330 SUPERFAMILY SSF52283 1 136 5.86E-40 T 05-07-2017 K08M4_RS15710 0308ed1f2392a2b3e1e100fa458af010 330 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 195 217 - T 05-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site K08M4_RS15710 0308ed1f2392a2b3e1e100fa458af010 330 Gene3D G3DSA:3.40.50.720 2 138 3.7E-45 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS15710 0308ed1f2392a2b3e1e100fa458af010 330 Gene3D G3DSA:3.40.50.720 139 304 5.9E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS15710 0308ed1f2392a2b3e1e100fa458af010 330 SUPERFAMILY SSF51735 103 299 7.19E-54 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS15710 0308ed1f2392a2b3e1e100fa458af010 330 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 05-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site K08M4_RS15710 0308ed1f2392a2b3e1e100fa458af010 330 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 15 328 5.4E-30 T 05-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 K08M4_RS15710 0308ed1f2392a2b3e1e100fa458af010 330 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 148 175 - T 05-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 K08M4_RS05225 ddfaf054dca8b21b4b894833256cc1c5 353 Pfam PF01343 Peptidase family S49 166 314 8.6E-47 T 05-07-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 K08M4_RS05225 ddfaf054dca8b21b4b894833256cc1c5 353 Pfam PF08496 Peptidase family S49 N-terminal 2 162 4.8E-55 T 05-07-2017 IPR013703 Peptidase S49, N-terminal proteobacteria GO:0004252|GO:0005886 K08M4_RS05225 ddfaf054dca8b21b4b894833256cc1c5 353 Gene3D G3DSA:3.90.226.10 102 209 4.7E-35 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS05225 ddfaf054dca8b21b4b894833256cc1c5 353 Gene3D G3DSA:3.90.226.10 275 310 4.7E-35 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS05225 ddfaf054dca8b21b4b894833256cc1c5 353 SUPERFAMILY SSF52096 103 213 1.76E-29 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS05225 ddfaf054dca8b21b4b894833256cc1c5 353 SUPERFAMILY SSF52096 244 303 1.76E-29 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS02730 cbcca835edf669130c1f9e5ea87997ab 172 PIRSF PIRSF006160 1 162 2.9E-65 T 05-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 K08M4_RS02730 cbcca835edf669130c1f9e5ea87997ab 172 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 6.2E-51 T 05-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 K08M4_RS02730 cbcca835edf669130c1f9e5ea87997ab 172 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 6.2E-51 T 05-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 K08M4_RS02730 cbcca835edf669130c1f9e5ea87997ab 172 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 6.2E-51 T 05-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 K08M4_RS02730 cbcca835edf669130c1f9e5ea87997ab 172 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 77 95 6.2E-51 T 05-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 K08M4_RS02730 cbcca835edf669130c1f9e5ea87997ab 172 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 121 140 6.2E-51 T 05-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 K08M4_RS02730 cbcca835edf669130c1f9e5ea87997ab 172 SUPERFAMILY SSF63411 4 162 1.74E-65 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 K08M4_RS02730 cbcca835edf669130c1f9e5ea87997ab 172 Gene3D G3DSA:3.30.1360.80 1 171 6.3E-75 T 05-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 K08M4_RS02730 cbcca835edf669130c1f9e5ea87997ab 172 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 154 3.0E-60 T 05-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 K08M4_RS02730 cbcca835edf669130c1f9e5ea87997ab 172 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 159 35.021 T 05-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 K08M4_RS02730 cbcca835edf669130c1f9e5ea87997ab 172 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 9 154 1.0E-73 T 05-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 K08M4_RS00405 3544bba30b2360db92cf4a9b5c76ca02 842 Pfam PF01295 Adenylate cyclase, class-I 226 828 2.1E-251 T 05-07-2017 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 K08M4_RS00405 3544bba30b2360db92cf4a9b5c76ca02 842 Pfam PF12633 Adenylate cyclase NT domain 5 198 3.1E-78 T 05-07-2017 IPR024685 Adenylate cyclase class-I, N-terminal domain KEGG: 00230+4.6.1.1 K08M4_RS00405 3544bba30b2360db92cf4a9b5c76ca02 842 PIRSF PIRSF001444 1 842 0.0 T 05-07-2017 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 K08M4_RS14000 1bfcebb9cf337acacd0d454dbea4a3d5 269 SUPERFAMILY SSF46946 130 221 6.33E-29 T 05-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 K08M4_RS14000 1bfcebb9cf337acacd0d454dbea4a3d5 269 SUPERFAMILY SSF81624 2 138 9.81E-40 T 05-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 K08M4_RS14000 1bfcebb9cf337acacd0d454dbea4a3d5 269 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 1.1E-31 T 05-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 K08M4_RS14000 1bfcebb9cf337acacd0d454dbea4a3d5 269 SUPERFAMILY SSF57716 217 268 7.41E-16 T 05-07-2017 K08M4_RS14000 1bfcebb9cf337acacd0d454dbea4a3d5 269 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 269 42.146 T 05-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 K08M4_RS14000 1bfcebb9cf337acacd0d454dbea4a3d5 269 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 268 3.3E-94 T 05-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 K08M4_RS14000 1bfcebb9cf337acacd0d454dbea4a3d5 269 SMART SM01232 129 221 7.2E-42 T 05-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 K08M4_RS14000 1bfcebb9cf337acacd0d454dbea4a3d5 269 Pfam PF06827 Zinc finger found in FPG and IleRS 241 268 6.9E-7 T 05-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 K08M4_RS14000 1bfcebb9cf337acacd0d454dbea4a3d5 269 SMART SM00898 2 115 2.7E-51 T 05-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 K08M4_RS14000 1bfcebb9cf337acacd0d454dbea4a3d5 269 Gene3D G3DSA:1.10.8.50 130 268 4.3E-49 T 05-07-2017 K08M4_RS14000 1bfcebb9cf337acacd0d454dbea4a3d5 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 130 218 7.3E-27 T 05-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 K08M4_RS14000 1bfcebb9cf337acacd0d454dbea4a3d5 269 Gene3D G3DSA:3.20.190.10 2 126 7.7E-37 T 05-07-2017 K08M4_RS01150 b072028cbfeea868b9475b27ead48b56 733 SMART SM00490 492 589 1.5E-11 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS01150 b072028cbfeea868b9475b27ead48b56 733 Pfam PF00271 Helicase conserved C-terminal domain 513 588 2.8E-7 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS01150 b072028cbfeea868b9475b27ead48b56 733 Pfam PF00270 DEAD/DEAH box helicase 204 362 1.1E-15 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS01150 b072028cbfeea868b9475b27ead48b56 733 SUPERFAMILY SSF52540 155 378 9.5E-39 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01150 b072028cbfeea868b9475b27ead48b56 733 Hamap MF_00983 Probable primosomal protein N' [priA]. 8 732 25.036 T 05-07-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 K08M4_RS01150 b072028cbfeea868b9475b27ead48b56 733 SMART SM00487 196 395 1.2E-19 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS01150 b072028cbfeea868b9475b27ead48b56 733 TIGRFAM TIGR00595 priA: primosomal protein N' 221 729 6.3E-191 T 05-07-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 K08M4_RS01150 b072028cbfeea868b9475b27ead48b56 733 Gene3D G3DSA:3.40.50.300 459 632 1.5E-33 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01150 b072028cbfeea868b9475b27ead48b56 733 Gene3D G3DSA:3.40.50.300 196 380 2.7E-37 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01150 b072028cbfeea868b9475b27ead48b56 733 SUPERFAMILY SSF52540 460 613 3.66E-27 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06570 d52fd1f99d855fc41301c9b9791cf80a 598 Gene3D G3DSA:3.40.390.10 380 421 2.3E-4 T 05-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 K08M4_RS06570 d52fd1f99d855fc41301c9b9791cf80a 598 SUPERFAMILY SSF55486 10 580 7.33E-90 T 05-07-2017 K08M4_RS06570 d52fd1f99d855fc41301c9b9791cf80a 598 Pfam PF01432 Peptidase family M3 334 580 2.8E-24 T 05-07-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 K08M4_RS06570 d52fd1f99d855fc41301c9b9791cf80a 598 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 5 593 1.5E-202 T 05-07-2017 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 K08M4_RS06570 d52fd1f99d855fc41301c9b9791cf80a 598 Pfam PF08439 Oligopeptidase F 107 174 3.5E-9 T 05-07-2017 IPR013647 Oligopeptidase F, N-terminal domain K08M4_RS00235 2a550d0c524865c5493562fc6a88f13b 165 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 165 35.391 T 05-07-2017 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 K08M4_RS00235 2a550d0c524865c5493562fc6a88f13b 165 SUPERFAMILY SSF52833 1 163 1.28E-41 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS00235 2a550d0c524865c5493562fc6a88f13b 165 Pfam PF08534 Redoxin 20 162 6.2E-26 T 05-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 K08M4_RS00235 2a550d0c524865c5493562fc6a88f13b 165 Gene3D G3DSA:3.40.30.10 3 165 6.3E-44 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS00235 2a550d0c524865c5493562fc6a88f13b 165 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 05-07-2017 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 K08M4_RS17855 80129f9aed13a2795130dba3bb5f1bdf 210 Gene3D G3DSA:1.10.10.10 146 205 6.9E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS17855 80129f9aed13a2795130dba3bb5f1bdf 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 201 1.5E-22 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS17855 80129f9aed13a2795130dba3bb5f1bdf 210 SMART SM00421 145 202 5.3E-23 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS17855 80129f9aed13a2795130dba3bb5f1bdf 210 SMART SM00448 4 117 1.4E-34 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS17855 80129f9aed13a2795130dba3bb5f1bdf 210 SUPERFAMILY SSF52172 5 134 1.32E-34 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS17855 80129f9aed13a2795130dba3bb5f1bdf 210 SUPERFAMILY SSF46894 130 204 7.82E-21 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS17855 80129f9aed13a2795130dba3bb5f1bdf 210 Pfam PF00072 Response regulator receiver domain 6 117 2.3E-31 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS17855 80129f9aed13a2795130dba3bb5f1bdf 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 3.4E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS17855 80129f9aed13a2795130dba3bb5f1bdf 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 3.4E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS17855 80129f9aed13a2795130dba3bb5f1bdf 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 3.4E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS17855 80129f9aed13a2795130dba3bb5f1bdf 210 Gene3D G3DSA:3.40.50.2300 4 145 5.6E-39 T 05-07-2017 K08M4_RS17855 80129f9aed13a2795130dba3bb5f1bdf 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS04045 065b3fb7b4dd786d85eed95b7205c4f8 137 Pfam PF00460 Flagella basal body rod protein 7 32 1.8E-7 T 05-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 K08M4_RS04045 065b3fb7b4dd786d85eed95b7205c4f8 137 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 05-07-2017 IPR019776 Flagellar basal body rod protein, conserved site K08M4_RS04045 065b3fb7b4dd786d85eed95b7205c4f8 137 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 91 135 3.3E-12 T 05-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain K08M4_RS04045 065b3fb7b4dd786d85eed95b7205c4f8 137 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 137 1.5E-51 T 05-07-2017 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 K08M4_RS20145 a12dcd8196bd0a30cf5113315241936b 299 Pfam PF00892 EamA-like transporter family 157 287 1.2E-9 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS20145 a12dcd8196bd0a30cf5113315241936b 299 Pfam PF00892 EamA-like transporter family 12 142 2.9E-16 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS20145 a12dcd8196bd0a30cf5113315241936b 299 SUPERFAMILY SSF103481 191 290 8.37E-15 T 05-07-2017 K08M4_RS20145 a12dcd8196bd0a30cf5113315241936b 299 SUPERFAMILY SSF103481 47 145 1.15E-17 T 05-07-2017 K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 SUPERFAMILY SSF55785 475 599 1.13E-20 T 05-07-2017 IPR000014 PAS domain K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 Pfam PF00990 Diguanylate cyclase, GGDEF domain 612 769 1.3E-33 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 Pfam PF13426 PAS domain 501 600 7.7E-10 T 05-07-2017 IPR000014 PAS domain K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 Pfam PF13426 PAS domain 387 476 1.6 T 05-07-2017 IPR000014 PAS domain K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 Pfam PF00563 EAL domain 793 1027 2.6E-56 T 05-07-2017 IPR001633 EAL domain K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 SMART SM00052 785 1032 2.0E-59 T 05-07-2017 IPR001633 EAL domain K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 SMART SM00091 490 555 0.0044 T 05-07-2017 IPR000014 PAS domain K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 SMART SM00091 366 431 13.0 T 05-07-2017 IPR000014 PAS domain K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 Gene3D G3DSA:3.30.450.20 354 475 7.0E-9 T 05-07-2017 K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 Gene3D G3DSA:3.30.450.20 476 599 1.6E-19 T 05-07-2017 K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 SUPERFAMILY SSF55785 353 476 2.23E-8 T 05-07-2017 IPR000014 PAS domain K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 488 608 4.9E-15 T 05-07-2017 IPR000014 PAS domain K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 363 485 1.4E-6 T 05-07-2017 IPR000014 PAS domain K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 Gene3D G3DSA:3.30.70.270 614 774 4.0E-43 T 05-07-2017 K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 Gene3D G3DSA:3.20.20.450 792 1039 1.7E-68 T 05-07-2017 IPR001633 EAL domain K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 608 771 1.9E-33 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 SMART SM00267 601 773 2.7E-46 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 SMART SM00086 436 478 31.0 T 05-07-2017 IPR001610 PAC motif K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 SMART SM00086 563 601 1.5 T 05-07-2017 IPR001610 PAC motif K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 SUPERFAMILY SSF55073 617 773 1.49E-39 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS14545 a8a323aa920fd9b6ef8f80a826c15577 1042 SUPERFAMILY SSF141868 791 1039 1.44E-69 T 05-07-2017 IPR001633 EAL domain K08M4_RS05035 509ad97bf5ff0fdbacf33dd6050aba65 279 Hamap MF_00696 Fatty acid metabolism regulator protein [fadR]. 1 279 135.599 T 05-07-2017 IPR014178 Fatty acid response transcription factor FadR GO:0000062|GO:0003677|GO:0003700|GO:0019217 K08M4_RS05035 509ad97bf5ff0fdbacf33dd6050aba65 279 Gene3D G3DSA:1.10.10.10 12 74 9.6E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05035 509ad97bf5ff0fdbacf33dd6050aba65 279 SUPERFAMILY SSF46785 12 74 1.57E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05035 509ad97bf5ff0fdbacf33dd6050aba65 279 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 3.5E-9 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS05035 509ad97bf5ff0fdbacf33dd6050aba65 279 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 3.5E-9 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS05035 509ad97bf5ff0fdbacf33dd6050aba65 279 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 71 1.6E-20 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS05035 509ad97bf5ff0fdbacf33dd6050aba65 279 SUPERFAMILY SSF48008 178 270 2.88E-54 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS05035 509ad97bf5ff0fdbacf33dd6050aba65 279 SUPERFAMILY SSF48008 79 137 2.88E-54 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS05035 509ad97bf5ff0fdbacf33dd6050aba65 279 SMART SM00345 12 71 1.7E-22 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS05035 509ad97bf5ff0fdbacf33dd6050aba65 279 Pfam PF07840 FadR C-terminal domain 72 274 4.4E-65 T 05-07-2017 IPR028374 FadR, C-terminal domain GO:0000062|GO:0019217 K08M4_RS05035 509ad97bf5ff0fdbacf33dd6050aba65 279 Gene3D G3DSA:1.20.120.530 80 137 4.0E-65 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS05035 509ad97bf5ff0fdbacf33dd6050aba65 279 Gene3D G3DSA:1.20.120.530 178 278 4.0E-65 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS05035 509ad97bf5ff0fdbacf33dd6050aba65 279 TIGRFAM TIGR02812 fadR_gamma: fatty acid metabolism transcriptional regulator FadR 2 276 8.8E-113 T 05-07-2017 IPR014178 Fatty acid response transcription factor FadR GO:0000062|GO:0003677|GO:0003700|GO:0019217 K08M4_RS19215 08de1df180ac72c1b5217eb79eae78b0 262 SUPERFAMILY SSF56436 37 261 2.83E-57 T 05-07-2017 IPR016187 C-type lectin fold K08M4_RS19215 08de1df180ac72c1b5217eb79eae78b0 262 Gene3D G3DSA:3.90.1580.10 29 261 4.4E-61 T 05-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 K08M4_RS19215 08de1df180ac72c1b5217eb79eae78b0 262 Pfam PF03781 Sulfatase-modifying factor enzyme 1 38 259 3.8E-49 T 05-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 K08M4_RS21615 a76e5c58b56a7f52cfb05d936f5c09eb 79 SUPERFAMILY SSF54928 2 78 2.96E-25 T 05-07-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 K08M4_RS21615 a76e5c58b56a7f52cfb05d936f5c09eb 79 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 3 73 4.6E-22 T 05-07-2017 IPR000504 RNA recognition motif domain GO:0003676 K08M4_RS21615 a76e5c58b56a7f52cfb05d936f5c09eb 79 Gene3D G3DSA:3.30.70.330 2 78 9.9E-26 T 05-07-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 K08M4_RS21615 a76e5c58b56a7f52cfb05d936f5c09eb 79 SMART SM00360 2 75 1.2E-23 T 05-07-2017 IPR000504 RNA recognition motif domain GO:0003676 K08M4_RS02120 7752dbc423805620640348b4c02305f7 306 Hamap MF_00313 Glutaminase [glsA]. 4 306 47.261 T 05-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 K08M4_RS02120 7752dbc423805620640348b4c02305f7 306 Pfam PF04960 Glutaminase 22 306 1.2E-112 T 05-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 K08M4_RS02120 7752dbc423805620640348b4c02305f7 306 SUPERFAMILY SSF56601 3 306 4.01E-114 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS02120 7752dbc423805620640348b4c02305f7 306 TIGRFAM TIGR03814 Gln_ase: glutaminase A 8 306 6.7E-130 T 05-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 K08M4_RS02120 7752dbc423805620640348b4c02305f7 306 Gene3D G3DSA:3.40.710.10 2 306 1.0E-124 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS19435 ff2b59581299d59438c389776f5fe3f7 104 SUPERFAMILY SSF46894 4 99 5.39E-17 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS19435 ff2b59581299d59438c389776f5fe3f7 104 Gene3D G3DSA:1.10.10.10 6 102 8.1E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19435 ff2b59581299d59438c389776f5fe3f7 104 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 99 3.5E-11 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS19435 ff2b59581299d59438c389776f5fe3f7 104 SMART SM00862 24 99 5.9E-8 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS06710 b1deaf53ebb85c0cc30286e58104699a 222 Pfam PF10881 Protein of unknown function (DUF2726) 38 160 1.6E-38 T 05-07-2017 IPR024402 Domain of unknown function DUF2726 K08M4_RS06710 b1deaf53ebb85c0cc30286e58104699a 222 PIRSF PIRSF028063 1 221 1.1E-125 T 05-07-2017 IPR014538 Uncharacterised conserved protein, topoisomerase zinc finger K08M4_RS06710 b1deaf53ebb85c0cc30286e58104699a 222 Gene3D G3DSA:3.30.65.10 174 212 4.1E-4 T 05-07-2017 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 SUPERFAMILY SSF51905 144 307 2.02E-26 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 PIRSF PIRSF037149 1 836 0.0 T 05-07-2017 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 SUPERFAMILY SSF55124 503 642 7.85E-27 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 1.1E-17 T 05-07-2017 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.1E-17 T 05-07-2017 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 1.1E-17 T 05-07-2017 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.1E-17 T 05-07-2017 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 1.1E-17 T 05-07-2017 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 561 622 2.0E-9 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 Gene3D G3DSA:3.50.50.60 2 104 2.8E-24 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 802 0.0 T 05-07-2017 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 680 696 - T 05-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 283 3.2E-52 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 Pfam PF04324 BFD-like [2Fe-2S] binding domain 424 472 7.4E-14 T 05-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 Pfam PF04324 BFD-like [2Fe-2S] binding domain 486 534 2.2E-5 T 05-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 PRINTS PR00397 Sirohaem Fe-binding site signature 637 655 1.8E-6 T 05-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 PRINTS PR00397 Sirohaem Fe-binding site signature 680 698 1.8E-6 T 05-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 7.2E-8 T 05-07-2017 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 7.2E-8 T 05-07-2017 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 7.2E-8 T 05-07-2017 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 7.2E-8 T 05-07-2017 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 SUPERFAMILY SSF51905 2 187 6.07E-39 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 Gene3D G3DSA:3.50.50.60 105 306 1.7E-48 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 Gene3D G3DSA:3.30.413.10 633 771 1.4E-35 T 05-07-2017 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 633 772 1.9E-19 T 05-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS19520 087585839e395775f52a10d75e2dada8 860 SUPERFAMILY SSF56014 634 810 2.49E-50 T 05-07-2017 K08M4_RS17025 6ce2153924b55c593d4d26973ec578d1 106 SUPERFAMILY SSF117782 1 105 2.22E-38 T 05-07-2017 IPR002765 Uncharacterised protein family UPF0145 K08M4_RS17025 6ce2153924b55c593d4d26973ec578d1 106 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 105 24.288 T 05-07-2017 IPR002765 Uncharacterised protein family UPF0145 K08M4_RS17025 6ce2153924b55c593d4d26973ec578d1 106 Gene3D G3DSA:3.30.110.70 1 105 2.4E-37 T 05-07-2017 IPR002765 Uncharacterised protein family UPF0145 K08M4_RS17025 6ce2153924b55c593d4d26973ec578d1 106 Pfam PF01906 Putative heavy-metal-binding 1 105 2.8E-39 T 05-07-2017 IPR002765 Uncharacterised protein family UPF0145 K08M4_RS10315 dc3ff723ff40901da231bd19462faf20 288 SUPERFAMILY SSF52096 21 284 1.8E-78 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS10315 dc3ff723ff40901da231bd19462faf20 288 Pfam PF00378 Enoyl-CoA hydratase/isomerase 34 282 3.2E-78 T 05-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 K08M4_RS10315 dc3ff723ff40901da231bd19462faf20 288 Gene3D G3DSA:3.90.226.10 25 225 3.1E-69 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS10315 dc3ff723ff40901da231bd19462faf20 288 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 126 146 - T 05-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 K08M4_RS10315 dc3ff723ff40901da231bd19462faf20 288 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 18 287 55.669 T 05-07-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 K08M4_RS10315 dc3ff723ff40901da231bd19462faf20 288 TIGRFAM TIGR01929 menB: naphthoate synthase 25 284 5.4E-145 T 05-07-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 K08M4_RS10315 dc3ff723ff40901da231bd19462faf20 288 Gene3D G3DSA:1.10.12.10 226 276 9.6E-31 T 05-07-2017 IPR014748 Crontonase, C-terminal K08M4_RS21315 9ba49d13396c5614c3cbda5d8556f743 289 Gene3D G3DSA:1.10.10.60 60 112 4.5E-19 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS21315 9ba49d13396c5614c3cbda5d8556f743 289 Gene3D G3DSA:3.20.80.10 138 286 7.3E-28 T 05-07-2017 IPR011256 Regulatory factor, effector binding domain K08M4_RS21315 9ba49d13396c5614c3cbda5d8556f743 289 Gene3D G3DSA:1.10.10.60 5 59 1.3E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS21315 9ba49d13396c5614c3cbda5d8556f743 289 Pfam PF06445 GyrI-like small molecule binding domain 138 286 4.7E-28 T 05-07-2017 IPR029442 GyrI-like small molecule binding domain K08M4_RS21315 9ba49d13396c5614c3cbda5d8556f743 289 SMART SM00342 23 107 6.0E-31 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS21315 9ba49d13396c5614c3cbda5d8556f743 289 SUPERFAMILY SSF46689 6 57 1.7E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS21315 9ba49d13396c5614c3cbda5d8556f743 289 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 60 103 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 K08M4_RS21315 9ba49d13396c5614c3cbda5d8556f743 289 SUPERFAMILY SSF55136 138 286 1.92E-26 T 05-07-2017 IPR011256 Regulatory factor, effector binding domain K08M4_RS21315 9ba49d13396c5614c3cbda5d8556f743 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 76 91 2.9E-7 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS21315 9ba49d13396c5614c3cbda5d8556f743 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 91 107 2.9E-7 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS21315 9ba49d13396c5614c3cbda5d8556f743 289 Pfam PF12833 Helix-turn-helix domain 29 108 4.4E-25 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS21315 9ba49d13396c5614c3cbda5d8556f743 289 SMART SM00871 137 287 7.2E-16 T 05-07-2017 IPR010499 Bacterial transcription activator, effector binding K08M4_RS21315 9ba49d13396c5614c3cbda5d8556f743 289 SUPERFAMILY SSF46689 60 110 1.48E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS18020 7dfa1cffadab2fca4188fabc6de4928a 151 Gene3D G3DSA:2.60.40.420 24 146 1.2E-28 T 05-07-2017 IPR008972 Cupredoxin K08M4_RS18020 7dfa1cffadab2fca4188fabc6de4928a 151 SUPERFAMILY SSF49503 34 133 4.71E-22 T 05-07-2017 IPR008972 Cupredoxin K08M4_RS18020 7dfa1cffadab2fca4188fabc6de4928a 151 PRINTS PR00155 Amicyanin family signature 39 58 1.1E-12 T 05-07-2017 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 K08M4_RS18020 7dfa1cffadab2fca4188fabc6de4928a 151 PRINTS PR00155 Amicyanin family signature 96 111 1.1E-12 T 05-07-2017 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 K08M4_RS18020 7dfa1cffadab2fca4188fabc6de4928a 151 PRINTS PR00155 Amicyanin family signature 59 74 1.1E-12 T 05-07-2017 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 K08M4_RS18020 7dfa1cffadab2fca4188fabc6de4928a 151 PRINTS PR00155 Amicyanin family signature 80 95 1.1E-12 T 05-07-2017 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 K08M4_RS18020 7dfa1cffadab2fca4188fabc6de4928a 151 PRINTS PR00156 Type I copper blue protein family signature 59 74 2.9E-6 T 05-07-2017 IPR001235 Blue (type 1) copper protein, plastocyanin-type GO:0005507|GO:0009055 K08M4_RS18020 7dfa1cffadab2fca4188fabc6de4928a 151 PRINTS PR00156 Type I copper blue protein family signature 91 105 2.9E-6 T 05-07-2017 IPR001235 Blue (type 1) copper protein, plastocyanin-type GO:0005507|GO:0009055 K08M4_RS18020 7dfa1cffadab2fca4188fabc6de4928a 151 PRINTS PR00156 Type I copper blue protein family signature 45 58 2.9E-6 T 05-07-2017 IPR001235 Blue (type 1) copper protein, plastocyanin-type GO:0005507|GO:0009055 K08M4_RS18020 7dfa1cffadab2fca4188fabc6de4928a 151 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 35 113 9.7E-8 T 05-07-2017 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 K08M4_RS02515 dde9780ba58207f963662b3287f24913 93 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 35.82 T 05-07-2017 IPR023081 Cell division protein FtsB K08M4_RS02515 dde9780ba58207f963662b3287f24913 93 Pfam PF04977 Septum formation initiator 12 89 2.3E-27 T 05-07-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 K08M4_RS15090 6f92736aa3238f995431ee2bfc61d7b5 162 Gene3D G3DSA:3.30.70.920 61 149 2.4E-29 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS15090 6f92736aa3238f995431ee2bfc61d7b5 162 ProSitePatterns PS00519 AsnC-type HTH domain signature. 24 50 - T 05-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site K08M4_RS15090 6f92736aa3238f995431ee2bfc61d7b5 162 SMART SM00344 6 115 9.4E-41 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 K08M4_RS15090 6f92736aa3238f995431ee2bfc61d7b5 162 SUPERFAMILY SSF46785 5 65 2.77E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15090 6f92736aa3238f995431ee2bfc61d7b5 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 3.2E-14 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS15090 6f92736aa3238f995431ee2bfc61d7b5 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 3.2E-14 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS15090 6f92736aa3238f995431ee2bfc61d7b5 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 3.2E-14 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS15090 6f92736aa3238f995431ee2bfc61d7b5 162 Gene3D G3DSA:1.10.10.10 2 57 1.5E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15090 6f92736aa3238f995431ee2bfc61d7b5 162 SUPERFAMILY SSF54909 66 151 8.98E-22 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel K08M4_RS15090 6f92736aa3238f995431ee2bfc61d7b5 162 Pfam PF01037 Lrp/AsnC ligand binding domain 72 146 2.1E-23 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS15090 6f92736aa3238f995431ee2bfc61d7b5 162 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 53 1.0E-15 T 05-07-2017 K08M4_RS05395 ae152d70fd641754ddd22e288fed5c2d 426 ProSitePatterns PS00885 EPSP synthase signature 2. 339 357 - T 05-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 K08M4_RS05395 ae152d70fd641754ddd22e288fed5c2d 426 ProSitePatterns PS00104 EPSP synthase signature 1. 90 104 - T 05-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 K08M4_RS05395 ae152d70fd641754ddd22e288fed5c2d 426 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 10 426 34.169 T 05-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 K08M4_RS05395 ae152d70fd641754ddd22e288fed5c2d 426 Gene3D G3DSA:3.65.10.10 239 422 9.4E-74 T 05-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 K08M4_RS05395 ae152d70fd641754ddd22e288fed5c2d 426 SUPERFAMILY SSF55205 1 424 7.85E-146 T 05-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 K08M4_RS05395 ae152d70fd641754ddd22e288fed5c2d 426 Gene3D G3DSA:3.65.10.10 22 238 4.0E-71 T 05-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 K08M4_RS05395 ae152d70fd641754ddd22e288fed5c2d 426 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 421 2.9E-156 T 05-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 K08M4_RS05395 ae152d70fd641754ddd22e288fed5c2d 426 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 14 424 1.5E-141 T 05-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 K08M4_RS05395 ae152d70fd641754ddd22e288fed5c2d 426 PIRSF PIRSF000505 1 425 1.4E-155 T 05-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 K08M4_RS17155 e8188db61534eaec6a075a346df6249f 703 SUPERFAMILY SSF55073 541 701 1.41E-30 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS17155 e8188db61534eaec6a075a346df6249f 703 Gene3D G3DSA:3.30.450.40 349 529 1.3E-16 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS17155 e8188db61534eaec6a075a346df6249f 703 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 537 701 5.3E-34 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS17155 e8188db61534eaec6a075a346df6249f 703 SMART SM00065 369 526 0.0041 T 05-07-2017 IPR003018 GAF domain GO:0005515 K08M4_RS17155 e8188db61534eaec6a075a346df6249f 703 Pfam PF00990 Diguanylate cyclase, GGDEF domain 537 697 1.8E-31 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS17155 e8188db61534eaec6a075a346df6249f 703 Pfam PF13185 GAF domain 368 514 1.8E-9 T 05-07-2017 IPR003018 GAF domain GO:0005515 K08M4_RS17155 e8188db61534eaec6a075a346df6249f 703 SUPERFAMILY SSF81901 51 279 5.49E-15 T 05-07-2017 K08M4_RS17155 e8188db61534eaec6a075a346df6249f 703 Gene3D G3DSA:3.30.70.270 538 700 9.3E-34 T 05-07-2017 K08M4_RS17155 e8188db61534eaec6a075a346df6249f 703 SMART SM00267 525 702 3.6E-29 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS17155 e8188db61534eaec6a075a346df6249f 703 Gene3D G3DSA:1.25.40.10 50 342 2.2E-16 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS17155 e8188db61534eaec6a075a346df6249f 703 SUPERFAMILY SSF55781 354 524 2.84E-15 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS12320 3d86516609f5ff6f058df40f2b323bfc 444 SUPERFAMILY SSF46689 350 438 6.4E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS12320 3d86516609f5ff6f058df40f2b323bfc 444 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 352 361 - T 05-07-2017 IPR025944 Sigma-54 interaction domain, conserved site K08M4_RS12320 3d86516609f5ff6f058df40f2b323bfc 444 Gene3D G3DSA:1.10.10.60 383 438 4.0E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS12320 3d86516609f5ff6f058df40f2b323bfc 444 SUPERFAMILY SSF52172 27 191 3.85E-5 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS12320 3d86516609f5ff6f058df40f2b323bfc 444 SUPERFAMILY SSF52540 146 377 5.69E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12320 3d86516609f5ff6f058df40f2b323bfc 444 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 419 439 3.9E-5 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS12320 3d86516609f5ff6f058df40f2b323bfc 444 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 402 419 3.9E-5 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS12320 3d86516609f5ff6f058df40f2b323bfc 444 Pfam PF02954 Bacterial regulatory protein, Fis family 396 435 6.2E-8 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS12320 3d86516609f5ff6f058df40f2b323bfc 444 Pfam PF00158 Sigma-54 interaction domain 147 306 3.1E-38 T 05-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 K08M4_RS12320 3d86516609f5ff6f058df40f2b323bfc 444 SMART SM00382 166 303 2.7E-4 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS12320 3d86516609f5ff6f058df40f2b323bfc 444 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 170 183 - T 05-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 K08M4_RS12320 3d86516609f5ff6f058df40f2b323bfc 444 Gene3D G3DSA:3.40.50.300 144 311 1.0E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12320 3d86516609f5ff6f058df40f2b323bfc 444 Gene3D G3DSA:1.10.8.60 312 382 1.5E-21 T 05-07-2017 K08M4_RS18470 cb28bba26987f07d4c807e779670eb19 145 Pfam PF11269 Protein of unknown function (DUF3069) 24 143 3.2E-51 T 05-07-2017 IPR021422 Protein of unknown function DUF3069 K08M4_RS18470 cb28bba26987f07d4c807e779670eb19 145 SUPERFAMILY SSF158675 1 143 1.83E-50 T 05-07-2017 IPR023132 Sama2622-like domain K08M4_RS18470 cb28bba26987f07d4c807e779670eb19 145 Gene3D G3DSA:1.10.3440.10 1 143 2.6E-52 T 05-07-2017 IPR023132 Sama2622-like domain K08M4_RS15195 c4a814a89b49a8b019d1c4e7ae51890a 200 SUPERFAMILY SSF48498 87 192 1.78E-16 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal K08M4_RS15195 c4a814a89b49a8b019d1c4e7ae51890a 200 SUPERFAMILY SSF46689 5 76 2.15E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS15195 c4a814a89b49a8b019d1c4e7ae51890a 200 Hamap MF_00768 HTH-type transcriptional regulator BetI [betI]. 1 198 93.634 T 05-07-2017 IPR017757 Transcriptional repressor BetI K08M4_RS15195 c4a814a89b49a8b019d1c4e7ae51890a 200 TIGRFAM TIGR03384 betaine_BetI: transcriptional repressor BetI 2 192 1.0E-72 T 05-07-2017 IPR017757 Transcriptional repressor BetI K08M4_RS15195 c4a814a89b49a8b019d1c4e7ae51890a 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site K08M4_RS15195 c4a814a89b49a8b019d1c4e7ae51890a 200 Gene3D G3DSA:1.10.357.10 1 195 3.6E-47 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS15195 c4a814a89b49a8b019d1c4e7ae51890a 200 Pfam PF13977 Bacterial transcriptional repressor 85 192 7.9E-30 T 05-07-2017 K08M4_RS15195 c4a814a89b49a8b019d1c4e7ae51890a 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 3.3E-11 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS19350 dda5ade551aa417f3539deea4fb9c6a2 718 SUPERFAMILY SSF46626 54 201 4.39E-26 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19350 dda5ade551aa417f3539deea4fb9c6a2 718 SUPERFAMILY SSF46626 302 420 2.27E-18 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19350 dda5ade551aa417f3539deea4fb9c6a2 718 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 124 196 2.0E-10 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19350 dda5ade551aa417f3539deea4fb9c6a2 718 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 587 669 2.9E-5 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19350 dda5ade551aa417f3539deea4fb9c6a2 718 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 211 286 1.3E-13 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19350 dda5ade551aa417f3539deea4fb9c6a2 718 Gene3D G3DSA:1.10.760.10 211 313 2.1E-25 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19350 dda5ade551aa417f3539deea4fb9c6a2 718 Gene3D G3DSA:1.10.760.10 117 204 6.1E-26 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19350 dda5ade551aa417f3539deea4fb9c6a2 718 Gene3D G3DSA:1.10.760.10 314 404 1.0E-14 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19350 dda5ade551aa417f3539deea4fb9c6a2 718 Gene3D G3DSA:1.10.760.10 455 560 2.3E-4 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19350 dda5ade551aa417f3539deea4fb9c6a2 718 SUPERFAMILY SSF46626 591 699 3.93E-13 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19350 dda5ade551aa417f3539deea4fb9c6a2 718 Pfam PF00034 Cytochrome c 306 404 2.5E-7 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19350 dda5ade551aa417f3539deea4fb9c6a2 718 SUPERFAMILY SSF46626 211 292 5.56E-19 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19350 dda5ade551aa417f3539deea4fb9c6a2 718 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 41 81 1.5E-8 T 05-07-2017 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal K08M4_RS19350 dda5ade551aa417f3539deea4fb9c6a2 718 Gene3D G3DSA:1.10.760.10 591 692 1.6E-14 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19350 dda5ade551aa417f3539deea4fb9c6a2 718 SUPERFAMILY SSF46626 459 561 2.07E-9 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS09440 2b9d569a145616ea2553deb787e83eab 461 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 461 39.437 T 05-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 K08M4_RS09440 2b9d569a145616ea2553deb787e83eab 461 Pfam PF09190 DALR domain 341 402 3.4E-24 T 05-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 K08M4_RS09440 2b9d569a145616ea2553deb787e83eab 461 Gene3D G3DSA:3.40.50.620 20 305 1.6E-113 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS09440 2b9d569a145616ea2553deb787e83eab 461 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 313 5.2E-142 T 05-07-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 K08M4_RS09440 2b9d569a145616ea2553deb787e83eab 461 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 460 5.7E-193 T 05-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 K08M4_RS09440 2b9d569a145616ea2553deb787e83eab 461 SUPERFAMILY SSF52374 1 313 8.85E-104 T 05-07-2017 K08M4_RS09440 2b9d569a145616ea2553deb787e83eab 461 Gene3D G3DSA:1.20.120.640 306 392 2.3E-27 T 05-07-2017 K08M4_RS09440 2b9d569a145616ea2553deb787e83eab 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 3.8E-29 T 05-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 K08M4_RS09440 2b9d569a145616ea2553deb787e83eab 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 3.8E-29 T 05-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 K08M4_RS09440 2b9d569a145616ea2553deb787e83eab 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 3.8E-29 T 05-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 K08M4_RS09440 2b9d569a145616ea2553deb787e83eab 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 3.8E-29 T 05-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 K08M4_RS09440 2b9d569a145616ea2553deb787e83eab 461 SUPERFAMILY SSF47323 316 460 7.45E-41 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS09440 2b9d569a145616ea2553deb787e83eab 461 SMART SM00840 341 402 4.3E-27 T 05-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 K08M4_RS13465 172c44b6db02fe4c0a08641ec7d7996e 75 PRINTS PR00974 Ribosomal protein S18 family signature 46 60 1.6E-18 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13465 172c44b6db02fe4c0a08641ec7d7996e 75 PRINTS PR00974 Ribosomal protein S18 family signature 38 45 1.6E-18 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13465 172c44b6db02fe4c0a08641ec7d7996e 75 PRINTS PR00974 Ribosomal protein S18 family signature 60 70 1.6E-18 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13465 172c44b6db02fe4c0a08641ec7d7996e 75 PRINTS PR00974 Ribosomal protein S18 family signature 28 38 1.6E-18 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13465 172c44b6db02fe4c0a08641ec7d7996e 75 Pfam PF01084 Ribosomal protein S18 19 68 2.4E-25 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13465 172c44b6db02fe4c0a08641ec7d7996e 75 Gene3D G3DSA:4.10.640.10 8 74 5.2E-33 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13465 172c44b6db02fe4c0a08641ec7d7996e 75 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 21 73 9.0E-24 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13465 172c44b6db02fe4c0a08641ec7d7996e 75 ProSitePatterns PS00057 Ribosomal protein S18 signature. 21 44 - T 05-07-2017 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13465 172c44b6db02fe4c0a08641ec7d7996e 75 SUPERFAMILY SSF46911 3 74 2.49E-29 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13465 172c44b6db02fe4c0a08641ec7d7996e 75 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 73 21.42 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13465 172c44b6db02fe4c0a08641ec7d7996e 75 TIGRFAM TIGR00165 S18: ribosomal protein bS18 4 73 6.2E-38 T 05-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS08335 6c2af5e6a09fa5d5a3a8ef507c97686d 718 Gene3D G3DSA:3.20.20.300 3 359 2.7E-106 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 K08M4_RS08335 6c2af5e6a09fa5d5a3a8ef507c97686d 718 SMART SM01217 638 707 3.1E-17 T 05-07-2017 IPR026891 Fibronectin type III-like domain K08M4_RS08335 6c2af5e6a09fa5d5a3a8ef507c97686d 718 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 23 340 4.6E-68 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 K08M4_RS08335 6c2af5e6a09fa5d5a3a8ef507c97686d 718 Gene3D G3DSA:3.40.50.1700 366 604 2.1E-65 T 05-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 K08M4_RS08335 6c2af5e6a09fa5d5a3a8ef507c97686d 718 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 380 601 9.2E-48 T 05-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 K08M4_RS08335 6c2af5e6a09fa5d5a3a8ef507c97686d 718 Pfam PF14310 Fibronectin type III-like domain 638 706 1.5E-13 T 05-07-2017 IPR026891 Fibronectin type III-like domain K08M4_RS08335 6c2af5e6a09fa5d5a3a8ef507c97686d 718 SUPERFAMILY SSF52279 380 604 1.31E-52 T 05-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 K08M4_RS08335 6c2af5e6a09fa5d5a3a8ef507c97686d 718 SUPERFAMILY SSF51445 2 379 3.9E-104 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS08335 6c2af5e6a09fa5d5a3a8ef507c97686d 718 PRINTS PR00133 Glycosyl hydrolase family 3 signature 263 281 4.7E-21 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 K08M4_RS08335 6c2af5e6a09fa5d5a3a8ef507c97686d 718 PRINTS PR00133 Glycosyl hydrolase family 3 signature 156 172 4.7E-21 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 K08M4_RS08335 6c2af5e6a09fa5d5a3a8ef507c97686d 718 PRINTS PR00133 Glycosyl hydrolase family 3 signature 91 107 4.7E-21 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 K08M4_RS08335 6c2af5e6a09fa5d5a3a8ef507c97686d 718 PRINTS PR00133 Glycosyl hydrolase family 3 signature 193 209 4.7E-21 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 K08M4_RS08335 6c2af5e6a09fa5d5a3a8ef507c97686d 718 PRINTS PR00133 Glycosyl hydrolase family 3 signature 110 129 4.7E-21 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 K08M4_RS09290 e6efc105708eacdeeaa7d3fe0afce09a 477 SUPERFAMILY SSF161070 11 452 1.02E-129 T 05-07-2017 K08M4_RS09290 e6efc105708eacdeeaa7d3fe0afce09a 477 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 92 118 2.8E-12 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS09290 e6efc105708eacdeeaa7d3fe0afce09a 477 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 316 336 2.8E-12 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS09290 e6efc105708eacdeeaa7d3fe0afce09a 477 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 19 40 2.8E-12 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS09290 e6efc105708eacdeeaa7d3fe0afce09a 477 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 48 67 2.8E-12 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS09290 e6efc105708eacdeeaa7d3fe0afce09a 477 Pfam PF00209 Sodium:neurotransmitter symporter family 151 448 1.3E-32 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS09290 e6efc105708eacdeeaa7d3fe0afce09a 477 Pfam PF00209 Sodium:neurotransmitter symporter family 11 119 4.8E-23 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS09290 e6efc105708eacdeeaa7d3fe0afce09a 477 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 35 49 - T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 Pfam PF03453 MoeA N-terminal region (domain I and II) 212 366 1.7E-33 T 05-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 13 169 6.0E-44 T 05-07-2017 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 Gene3D G3DSA:2.40.340.10 531 599 2.8E-28 T 05-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 SUPERFAMILY SSF63882 207 375 1.11E-46 T 05-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 Gene3D G3DSA:3.40.50.300 10 172 4.2E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 Pfam PF00994 Probable molybdopterin binding domain 379 515 6.3E-26 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 375 512 8.6E-32 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 Gene3D G3DSA:3.40.980.10 362 530 1.1E-60 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 Gene3D G3DSA:2.170.190.11 249 340 1.1E-26 T 05-07-2017 K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 SUPERFAMILY SSF53218 377 522 9.16E-43 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 13 145 8.5E-47 T 05-07-2017 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 SUPERFAMILY SSF63867 526 603 5.63E-22 T 05-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 PIRSF PIRSF036618 1 605 0.0 T 05-07-2017 IPR012182 Bifunctional molybdenum cofactor biosynthesis MobB/MoeA K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 Gene3D G3DSA:3.90.105.10 225 248 8.1E-19 T 05-07-2017 K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 Gene3D G3DSA:3.90.105.10 341 361 8.1E-19 T 05-07-2017 K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 SUPERFAMILY SSF52540 11 170 2.31E-24 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 Pfam PF03454 MoeA C-terminal region (domain IV) 530 601 3.6E-19 T 05-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS07460 ad9ab4783c3721440c19cb0f8b65d5c4 605 SMART SM00852 379 516 1.1E-38 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS16265 8d3b41394cef69c796bfdefbed3c0d32 301 Pfam PF05661 Protein of unknown function (DUF808) 4 291 2.3E-116 T 05-07-2017 IPR008526 Inner membrane protein YedI K08M4_RS16265 8d3b41394cef69c796bfdefbed3c0d32 301 PIRSF PIRSF016660 1 301 9.3E-121 T 05-07-2017 IPR008526 Inner membrane protein YedI K08M4_RS15830 f3feab0f26b366dc9f50f4eeec6f4918 309 Gene3D G3DSA:3.40.190.10 177 264 4.6E-10 T 05-07-2017 K08M4_RS15830 f3feab0f26b366dc9f50f4eeec6f4918 309 SUPERFAMILY SSF53850 89 300 1.16E-37 T 05-07-2017 K08M4_RS15830 f3feab0f26b366dc9f50f4eeec6f4918 309 SUPERFAMILY SSF46785 3 88 4.18E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15830 f3feab0f26b366dc9f50f4eeec6f4918 309 Gene3D G3DSA:1.10.10.10 3 84 2.4E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15830 f3feab0f26b366dc9f50f4eeec6f4918 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.8E-18 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS15830 f3feab0f26b366dc9f50f4eeec6f4918 309 Pfam PF03466 LysR substrate binding domain 88 295 5.5E-34 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS15830 f3feab0f26b366dc9f50f4eeec6f4918 309 Gene3D G3DSA:3.40.190.10 92 176 4.9E-21 T 05-07-2017 K08M4_RS05440 825d9192af57793f1d07893f0aed4693 334 Gene3D G3DSA:1.10.260.40 2 53 3.1E-25 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS05440 825d9192af57793f1d07893f0aed4693 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.5E-20 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS05440 825d9192af57793f1d07893f0aed4693 334 Hamap MF_01277 HTH-type transcriptional repressor PurR [purR]. 1 334 61.338 T 05-07-2017 IPR023588 Transcription regulator HTH, PurR GO:0006355 K08M4_RS05440 825d9192af57793f1d07893f0aed4693 334 SUPERFAMILY SSF53822 60 331 2.55E-94 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS05440 825d9192af57793f1d07893f0aed4693 334 SUPERFAMILY SSF47413 1 59 2.99E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS05440 825d9192af57793f1d07893f0aed4693 334 SMART SM00354 1 71 9.3E-38 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS05440 825d9192af57793f1d07893f0aed4693 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.0E-6 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS05440 825d9192af57793f1d07893f0aed4693 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.0E-6 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS05440 825d9192af57793f1d07893f0aed4693 334 Pfam PF13377 Periplasmic binding protein-like domain 170 330 4.3E-42 T 05-07-2017 K08M4_RS05440 825d9192af57793f1d07893f0aed4693 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 05-07-2017 K08M4_RS05440 825d9192af57793f1d07893f0aed4693 334 Gene3D G3DSA:3.40.50.2300 175 311 2.2E-55 T 05-07-2017 K08M4_RS05440 825d9192af57793f1d07893f0aed4693 334 Gene3D G3DSA:3.40.50.2300 54 174 1.1E-45 T 05-07-2017 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 SUPERFAMILY SSF158472 200 247 3.66E-6 T 05-07-2017 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 Pfam PF00672 HAMP domain 179 246 9.5E-10 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 Gene3D G3DSA:1.10.287.130 282 351 2.3E-19 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 Pfam PF01627 Hpt domain 841 926 2.3E-10 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 515 1.1E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 457 1.1E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 PRINTS PR00344 Bacterial sensor protein C-terminal signature 478 496 1.1E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 471 1.1E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 402 517 1.9E-28 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 SUPERFAMILY SSF52172 665 783 3.13E-36 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 SMART SM00388 290 355 9.2E-25 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 SMART SM00073 831 929 5.7E-7 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 Gene3D G3DSA:1.20.120.160 833 932 6.2E-18 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 SUPERFAMILY SSF47384 275 356 1.14E-22 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 Gene3D G3DSA:3.40.50.2300 665 784 7.5E-39 T 05-07-2017 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 SMART SM00387 402 518 2.4E-38 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 SMART SM00304 198 250 5.0E-5 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 SUPERFAMILY SSF55874 344 516 2.23E-44 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 SUPERFAMILY SSF47226 762 775 1.05E-21 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 SUPERFAMILY SSF47226 821 924 1.05E-21 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 Pfam PF00512 His Kinase A (phospho-acceptor) domain 291 355 2.2E-20 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 Gene3D G3DSA:3.30.565.10 356 519 1.1E-44 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 SMART SM00448 666 779 1.7E-36 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 Pfam PF00072 Response regulator receiver domain 668 778 9.4E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS02480 851386a2faf784e54162f2811d0d059f 937 Pfam PF09984 Uncharacterised signal transduction histidine kinase domain (DUF2222) 31 175 3.0E-54 T 05-07-2017 IPR019247 Histidine kinase BarA, N-terminal K08M4_RS09635 1269404e0f5743e703d713c18ec43228 136 SUPERFAMILY SSF81273 2 58 2.16E-16 T 05-07-2017 K08M4_RS09635 1269404e0f5743e703d713c18ec43228 136 Gene3D G3DSA:4.10.430.10 93 136 2.4E-24 T 05-07-2017 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 K08M4_RS09635 1269404e0f5743e703d713c18ec43228 136 Gene3D G3DSA:1.10.287.1050 1 58 6.1E-18 T 05-07-2017 IPR027454 Histone-like protein H-NS family, oligomerisation domain GO:0046983 K08M4_RS09635 1269404e0f5743e703d713c18ec43228 136 SMART SM00528 89 136 4.6E-23 T 05-07-2017 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 K08M4_RS09635 1269404e0f5743e703d713c18ec43228 136 Pfam PF00816 H-NS histone family 33 130 1.6E-19 T 05-07-2017 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 K08M4_RS09635 1269404e0f5743e703d713c18ec43228 136 SUPERFAMILY SSF81273 94 135 1.88E-11 T 05-07-2017 K08M4_RS09635 1269404e0f5743e703d713c18ec43228 136 PIRSF PIRSF002096 1 136 9.7E-55 T 05-07-2017 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 K08M4_RS09510 1269404e0f5743e703d713c18ec43228 136 SUPERFAMILY SSF81273 2 58 2.16E-16 T 05-07-2017 K08M4_RS09510 1269404e0f5743e703d713c18ec43228 136 Gene3D G3DSA:4.10.430.10 93 136 2.4E-24 T 05-07-2017 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 K08M4_RS09510 1269404e0f5743e703d713c18ec43228 136 Gene3D G3DSA:1.10.287.1050 1 58 6.1E-18 T 05-07-2017 IPR027454 Histone-like protein H-NS family, oligomerisation domain GO:0046983 K08M4_RS09510 1269404e0f5743e703d713c18ec43228 136 SMART SM00528 89 136 4.6E-23 T 05-07-2017 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 K08M4_RS09510 1269404e0f5743e703d713c18ec43228 136 Pfam PF00816 H-NS histone family 33 130 1.6E-19 T 05-07-2017 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 K08M4_RS09510 1269404e0f5743e703d713c18ec43228 136 SUPERFAMILY SSF81273 94 135 1.88E-11 T 05-07-2017 K08M4_RS09510 1269404e0f5743e703d713c18ec43228 136 PIRSF PIRSF002096 1 136 9.7E-55 T 05-07-2017 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 K08M4_RS20885 c502b85fc9d8638640ec75095a99c75f 335 Gene3D G3DSA:3.40.50.300 128 332 2.3E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20885 c502b85fc9d8638640ec75095a99c75f 335 Pfam PF07755 Protein of unknown function (DUF1611) 41 327 1.0E-98 T 05-07-2017 IPR011669 Protein of unknown function DUF1611 K08M4_RS20885 c502b85fc9d8638640ec75095a99c75f 335 Gene3D G3DSA:3.40.50.720 1 126 1.8E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS20885 c502b85fc9d8638640ec75095a99c75f 335 SUPERFAMILY SSF52540 2 332 1.7E-101 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20885 c502b85fc9d8638640ec75095a99c75f 335 PIRSF PIRSF026760 3 335 1.4E-99 T 05-07-2017 IPR011669 Protein of unknown function DUF1611 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 SUPERFAMILY SSF56672 526 932 7.78E-158 T 05-07-2017 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 SUPERFAMILY SSF47807 171 291 5.23E-30 T 05-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 SMART SM00475 7 267 1.6E-124 T 05-07-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 SMART SM00279 173 208 1.2E-13 T 05-07-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 171 270 9.9E-29 T 05-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 ProSitePatterns PS00447 DNA polymerase family A signature. 757 776 - T 05-07-2017 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 PRINTS PR00868 DNA-polymerase family A (pol I) signature 681 696 2.6E-77 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 PRINTS PR00868 DNA-polymerase family A (pol I) signature 879 892 2.6E-77 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 PRINTS PR00868 DNA-polymerase family A (pol I) signature 703 726 2.6E-77 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 PRINTS PR00868 DNA-polymerase family A (pol I) signature 733 746 2.6E-77 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 PRINTS PR00868 DNA-polymerase family A (pol I) signature 757 782 2.6E-77 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 PRINTS PR00868 DNA-polymerase family A (pol I) signature 658 680 2.6E-77 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 PRINTS PR00868 DNA-polymerase family A (pol I) signature 816 827 2.6E-77 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 PRINTS PR00868 DNA-polymerase family A (pol I) signature 794 805 2.6E-77 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 PRINTS PR00868 DNA-polymerase family A (pol I) signature 848 864 2.6E-77 T 05-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 Gene3D G3DSA:1.10.150.20 715 821 8.8E-36 T 05-07-2017 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 9 170 1.4E-54 T 05-07-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 Gene3D G3DSA:3.30.70.370 822 932 2.2E-64 T 05-07-2017 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 Gene3D G3DSA:3.30.70.370 667 714 2.2E-64 T 05-07-2017 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 SUPERFAMILY SSF88723 7 170 8.83E-58 T 05-07-2017 IPR029060 PIN domain-like K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 TIGRFAM TIGR00593 pola: DNA polymerase I 9 932 1.9E-286 T 05-07-2017 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 Gene3D G3DSA:1.20.1060.10 546 666 3.3E-38 T 05-07-2017 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 Gene3D G3DSA:1.10.150.20 187 253 2.9E-26 T 05-07-2017 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 SMART SM00474 333 520 3.6E-41 T 05-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 Pfam PF00476 DNA polymerase family A 556 929 2.0E-156 T 05-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 Pfam PF01612 3'-5' exonuclease 333 519 1.8E-39 T 05-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 Gene3D G3DSA:3.40.50.1010 8 186 1.1E-73 T 05-07-2017 IPR029060 PIN domain-like K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 SUPERFAMILY SSF53098 336 521 1.31E-54 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 Gene3D G3DSA:3.30.420.10 331 545 1.8E-83 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS14370 fc91f8d52d91f5032ea0899473772605 932 SMART SM00482 689 896 1.8E-113 T 05-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS04235 0d66110e9a055b29f35b69cfa3bf2943 295 Gene3D G3DSA:3.40.50.300 22 261 1.2E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04235 0d66110e9a055b29f35b69cfa3bf2943 295 SUPERFAMILY SSF52540 22 283 5.32E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04235 0d66110e9a055b29f35b69cfa3bf2943 295 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 25 213 1.7E-25 T 05-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain K08M4_RS04235 0d66110e9a055b29f35b69cfa3bf2943 295 PIRSF PIRSF003092 6 287 5.4E-85 T 05-07-2017 IPR025501 ATP binding protein MinD K08M4_RS13015 6df27182780c5d0f2e387899d790ad7c 323 Gene3D G3DSA:1.10.600.10 3 323 1.1E-102 T 05-07-2017 IPR008949 Isoprenoid synthase domain K08M4_RS13015 6df27182780c5d0f2e387899d790ad7c 323 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 05-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 K08M4_RS13015 6df27182780c5d0f2e387899d790ad7c 323 SUPERFAMILY SSF48576 4 322 2.88E-100 T 05-07-2017 IPR008949 Isoprenoid synthase domain K08M4_RS13015 6df27182780c5d0f2e387899d790ad7c 323 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 05-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 K08M4_RS13015 6df27182780c5d0f2e387899d790ad7c 323 Pfam PF00348 Polyprenyl synthetase 32 267 9.8E-73 T 05-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 K08M4_RS19120 c127f8e1eab4e73dc6b544ae51ccf61d 516 ProSitePatterns PS00217 Sugar transport proteins signature 2. 119 144 - T 05-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 K08M4_RS19120 c127f8e1eab4e73dc6b544ae51ccf61d 516 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 25 511 1.6E-121 T 05-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 K08M4_RS19120 c127f8e1eab4e73dc6b544ae51ccf61d 516 SUPERFAMILY SSF103473 491 514 1.19E-62 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS19120 c127f8e1eab4e73dc6b544ae51ccf61d 516 SUPERFAMILY SSF103473 12 204 1.19E-62 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS19120 c127f8e1eab4e73dc6b544ae51ccf61d 516 SUPERFAMILY SSF103473 260 431 1.19E-62 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS19120 c127f8e1eab4e73dc6b544ae51ccf61d 516 Gene3D G3DSA:1.20.1250.20 496 512 6.9E-13 T 05-07-2017 K08M4_RS19120 c127f8e1eab4e73dc6b544ae51ccf61d 516 Gene3D G3DSA:1.20.1250.20 272 454 6.9E-13 T 05-07-2017 K08M4_RS19120 c127f8e1eab4e73dc6b544ae51ccf61d 516 Gene3D G3DSA:1.20.1250.20 25 193 4.9E-26 T 05-07-2017 K08M4_RS19120 c127f8e1eab4e73dc6b544ae51ccf61d 516 Pfam PF07690 Major Facilitator Superfamily 28 421 7.2E-44 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS11540 df6f5c4111974818cac3cbfa04b54a1f 403 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 6 401 4.7E-166 T 05-07-2017 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 K08M4_RS11540 df6f5c4111974818cac3cbfa04b54a1f 403 Gene3D G3DSA:3.90.1150.10 283 398 9.0E-25 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS11540 df6f5c4111974818cac3cbfa04b54a1f 403 TIGRFAM TIGR03392 FeS_syn_CsdA: cysteine desulfurase, catalytic subunit CsdA 3 403 7.7E-158 T 05-07-2017 IPR022471 Cysteine desulphurase, catalytic subunit, CsdA GO:0016226|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 K08M4_RS11540 df6f5c4111974818cac3cbfa04b54a1f 403 Gene3D G3DSA:3.40.640.10 35 282 2.1E-82 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS11540 df6f5c4111974818cac3cbfa04b54a1f 403 Pfam PF00266 Aminotransferase class-V 24 392 8.5E-149 T 05-07-2017 IPR000192 Aminotransferase class V domain K08M4_RS11540 df6f5c4111974818cac3cbfa04b54a1f 403 PIRSF PIRSF005572 21 403 2.9E-53 T 05-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 K08M4_RS11540 df6f5c4111974818cac3cbfa04b54a1f 403 SUPERFAMILY SSF53383 3 400 1.34E-122 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 SUPERFAMILY SSF52009 348 466 8.11E-35 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 SUPERFAMILY SSF51621 461 786 1.54E-99 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 Gene3D G3DSA:3.20.20.60 480 787 5.0E-107 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 Gene3D G3DSA:3.50.30.10 372 470 1.2E-36 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 SUPERFAMILY SSF56059 1 383 1.88E-107 T 05-07-2017 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 PIRSF PIRSF000854 1 790 0.0 T 05-07-2017 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 693 711 - T 05-07-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 693 708 8.7E-6 T 05-07-2017 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 746 758 8.7E-6 T 05-07-2017 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 710 725 8.7E-6 T 05-07-2017 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 Pfam PF00391 PEP-utilising enzyme, mobile domain 383 454 5.2E-27 T 05-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 Gene3D G3DSA:3.30.470.20 194 355 1.4E-59 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 343 1.9E-119 T 05-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 413 424 - T 05-07-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 481 780 7.7E-63 T 05-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 Gene3D G3DSA:3.30.1490.20 1 192 3.2E-69 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 K08M4_RS20585 e8b607b5ff32c7a59e231a5b94ad7d9a 790 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 6 786 0.0 T 05-07-2017 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 K08M4_RS11005 872749d026732603adabdccb6aabfd8f 292 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 05-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS11005 872749d026732603adabdccb6aabfd8f 292 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 287 1.6E-115 T 05-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS11005 872749d026732603adabdccb6aabfd8f 292 Pfam PF00701 Dihydrodipicolinate synthetase family 2 288 8.0E-111 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 K08M4_RS11005 872749d026732603adabdccb6aabfd8f 292 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 05-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS11005 872749d026732603adabdccb6aabfd8f 292 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 288 65.167 T 05-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS11005 872749d026732603adabdccb6aabfd8f 292 Gene3D G3DSA:3.20.20.70 1 289 1.7E-114 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS11005 872749d026732603adabdccb6aabfd8f 292 PIRSF PIRSF001365 1 290 1.8E-92 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 K08M4_RS11005 872749d026732603adabdccb6aabfd8f 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 3.0E-34 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 K08M4_RS11005 872749d026732603adabdccb6aabfd8f 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 3.0E-34 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 K08M4_RS11005 872749d026732603adabdccb6aabfd8f 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 3.0E-34 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 K08M4_RS11005 872749d026732603adabdccb6aabfd8f 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 3.0E-34 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 K08M4_RS11005 872749d026732603adabdccb6aabfd8f 292 SMART SM01130 1 290 2.3E-140 T 05-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 K08M4_RS11005 872749d026732603adabdccb6aabfd8f 292 SUPERFAMILY SSF51569 2 288 2.09E-99 T 05-07-2017 K08M4_RS12985 12edd23163e368c440d6fe8398c7dbf7 159 Gene3D G3DSA:3.40.430.10 1 159 4.0E-61 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 K08M4_RS12985 12edd23163e368c440d6fe8398c7dbf7 159 PIRSF PIRSF000194 1 159 1.1E-61 T 05-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 K08M4_RS12985 12edd23163e368c440d6fe8398c7dbf7 159 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 14 36 - T 05-07-2017 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-113510|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-69205 K08M4_RS12985 12edd23163e368c440d6fe8398c7dbf7 159 PRINTS PR00070 Dihydrofolate reductase signature 92 106 7.2E-15 T 05-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 K08M4_RS12985 12edd23163e368c440d6fe8398c7dbf7 159 PRINTS PR00070 Dihydrofolate reductase signature 41 52 7.2E-15 T 05-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 K08M4_RS12985 12edd23163e368c440d6fe8398c7dbf7 159 PRINTS PR00070 Dihydrofolate reductase signature 14 24 7.2E-15 T 05-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 K08M4_RS12985 12edd23163e368c440d6fe8398c7dbf7 159 PRINTS PR00070 Dihydrofolate reductase signature 28 36 7.2E-15 T 05-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 K08M4_RS12985 12edd23163e368c440d6fe8398c7dbf7 159 SUPERFAMILY SSF53597 1 159 1.96E-57 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 K08M4_RS12985 12edd23163e368c440d6fe8398c7dbf7 159 Pfam PF00186 Dihydrofolate reductase 3 159 1.5E-60 T 05-07-2017 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 K08M4_RS11450 bb1deaab15eb2a0423bc313bc4e0d462 358 Hamap MF_01113 DNA polymerase IV [dinB]. 9 357 36.801 T 05-07-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 K08M4_RS11450 bb1deaab15eb2a0423bc313bc4e0d462 358 Gene3D G3DSA:3.30.70.270 74 172 4.1E-34 T 05-07-2017 K08M4_RS11450 bb1deaab15eb2a0423bc313bc4e0d462 358 Pfam PF00817 impB/mucB/samB family 15 162 8.2E-48 T 05-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 K08M4_RS11450 bb1deaab15eb2a0423bc313bc4e0d462 358 SUPERFAMILY SSF100879 249 357 5.69E-24 T 05-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 K08M4_RS11450 bb1deaab15eb2a0423bc313bc4e0d462 358 Gene3D G3DSA:1.10.150.20 173 242 1.0E-22 T 05-07-2017 K08M4_RS11450 bb1deaab15eb2a0423bc313bc4e0d462 358 Pfam PF11799 impB/mucB/samB family C-terminal domain 245 345 3.2E-6 T 05-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 K08M4_RS11450 bb1deaab15eb2a0423bc313bc4e0d462 358 Pfam PF11798 IMS family HHH motif 174 204 5.2E-6 T 05-07-2017 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 K08M4_RS11450 bb1deaab15eb2a0423bc313bc4e0d462 358 SUPERFAMILY SSF56672 7 242 2.94E-93 T 05-07-2017 K08M4_RS11450 bb1deaab15eb2a0423bc313bc4e0d462 358 Gene3D G3DSA:3.30.1490.100 245 358 1.9E-40 T 05-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 K08M4_RS15840 7c21fc402cb48a2727eeab7e415ceab6 405 SUPERFAMILY SSF118215 15 399 2.48E-96 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS15840 7c21fc402cb48a2727eeab7e415ceab6 405 Pfam PF00375 Sodium:dicarboxylate symporter family 15 398 1.3E-66 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS15840 7c21fc402cb48a2727eeab7e415ceab6 405 Gene3D G3DSA:1.10.3860.10 8 404 4.1E-85 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS15840 7c21fc402cb48a2727eeab7e415ceab6 405 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 3 404 36.602 T 05-07-2017 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 K08M4_RS15840 7c21fc402cb48a2727eeab7e415ceab6 405 PRINTS PR00173 Glutamate-aspartate symporter signature 13 33 5.7E-15 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS15840 7c21fc402cb48a2727eeab7e415ceab6 405 PRINTS PR00173 Glutamate-aspartate symporter signature 287 313 5.7E-15 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS15840 7c21fc402cb48a2727eeab7e415ceab6 405 PRINTS PR00173 Glutamate-aspartate symporter signature 185 204 5.7E-15 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS15840 7c21fc402cb48a2727eeab7e415ceab6 405 PRINTS PR00173 Glutamate-aspartate symporter signature 220 239 5.7E-15 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS15840 7c21fc402cb48a2727eeab7e415ceab6 405 PRINTS PR00173 Glutamate-aspartate symporter signature 322 341 5.7E-15 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS08800 410ea531c801f6cfda58cc3a974efbf6 73 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 4 64 3.2E-18 T 05-07-2017 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system K08M4_RS19830 9d23e187e6cd0aecd422558e83f3821a 384 SUPERFAMILY SSF56235 2 354 2.39E-54 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS19830 9d23e187e6cd0aecd422558e83f3821a 384 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 332 4.3E-38 T 05-07-2017 IPR029132 Choloylglycine hydrolase/NAAA C-terminal K08M4_RS19830 9d23e187e6cd0aecd422558e83f3821a 384 Gene3D G3DSA:3.60.60.10 2 353 3.3E-67 T 05-07-2017 IPR003199 Choloylglycine hydrolase/Peptidase C59 family GO:0016811 Reactome: R-HSA-1660662 K08M4_RS10465 f62aeb1b0f37cc338e385ede4c6754e1 564 Gene3D G3DSA:3.40.50.980 185 216 6.6E-40 T 05-07-2017 K08M4_RS10465 f62aeb1b0f37cc338e385ede4c6754e1 564 Gene3D G3DSA:3.40.50.980 23 152 6.6E-40 T 05-07-2017 K08M4_RS10465 f62aeb1b0f37cc338e385ede4c6754e1 564 SUPERFAMILY SSF56801 13 553 6.67E-149 T 05-07-2017 K08M4_RS10465 f62aeb1b0f37cc338e385ede4c6754e1 564 Pfam PF13193 AMP-binding enzyme C-terminal domain 470 544 2.7E-17 T 05-07-2017 IPR025110 AMP-binding enzyme C-terminal domain K08M4_RS10465 f62aeb1b0f37cc338e385ede4c6754e1 564 Gene3D G3DSA:3.40.50.980 217 380 2.3E-40 T 05-07-2017 K08M4_RS10465 f62aeb1b0f37cc338e385ede4c6754e1 564 Pfam PF00501 AMP-binding enzyme 29 461 2.0E-107 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 K08M4_RS10465 f62aeb1b0f37cc338e385ede4c6754e1 564 Gene3D G3DSA:2.30.38.10 381 455 8.0E-31 T 05-07-2017 K08M4_RS10465 f62aeb1b0f37cc338e385ede4c6754e1 564 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 05-07-2017 IPR020845 AMP-binding, conserved site K08M4_RS10465 f62aeb1b0f37cc338e385ede4c6754e1 564 Gene3D G3DSA:3.30.300.30 458 556 2.6E-27 T 05-07-2017 K08M4_RS11445 20bae48f275b371804bacd7753285332 644 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 6 350 8.7E-113 T 05-07-2017 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 K08M4_RS11445 20bae48f275b371804bacd7753285332 644 Pfam PF00270 DEAD/DEAH box helicase 18 177 9.6E-19 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS11445 20bae48f275b371804bacd7753285332 644 SUPERFAMILY SSF52540 56 338 2.19E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11445 20bae48f275b371804bacd7753285332 644 Pfam PF00271 Helicase conserved C-terminal domain 214 322 2.2E-17 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS11445 20bae48f275b371804bacd7753285332 644 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 130 139 - T 05-07-2017 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site GO:0003676|GO:0005524|GO:0008026 K08M4_RS11445 20bae48f275b371804bacd7753285332 644 Gene3D G3DSA:1.10.10.10 517 642 2.8E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS11445 20bae48f275b371804bacd7753285332 644 SMART SM00487 11 207 1.0E-28 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS11445 20bae48f275b371804bacd7753285332 644 Gene3D G3DSA:3.40.50.300 197 332 2.7E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11445 20bae48f275b371804bacd7753285332 644 Pfam PF16124 RecQ zinc-binding 515 562 5.2E-9 T 05-07-2017 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain K08M4_RS11445 20bae48f275b371804bacd7753285332 644 SMART SM00490 241 322 1.2E-27 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS11445 20bae48f275b371804bacd7753285332 644 Gene3D G3DSA:3.40.50.300 3 190 9.6E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13510 6e8a8e5cadbab41a6421af10d9934ccd 325 SMART SM00244 18 217 8.4E-45 T 05-07-2017 IPR001107 Band 7 domain K08M4_RS13510 6e8a8e5cadbab41a6421af10d9934ccd 325 TIGRFAM TIGR01932 hflC: HflC protein 1 317 8.8E-132 T 05-07-2017 IPR010200 HflC GO:0016021|GO:0052547 K08M4_RS13510 6e8a8e5cadbab41a6421af10d9934ccd 325 SUPERFAMILY SSF117892 55 141 2.09E-23 T 05-07-2017 IPR001107 Band 7 domain K08M4_RS13510 6e8a8e5cadbab41a6421af10d9934ccd 325 SUPERFAMILY SSF117892 172 222 2.09E-23 T 05-07-2017 IPR001107 Band 7 domain K08M4_RS13510 6e8a8e5cadbab41a6421af10d9934ccd 325 Pfam PF01145 SPFH domain / Band 7 family 22 232 1.9E-27 T 05-07-2017 IPR001107 Band 7 domain K08M4_RS13510 6e8a8e5cadbab41a6421af10d9934ccd 325 PIRSF PIRSF005651 1 324 1.6E-93 T 05-07-2017 IPR010200 HflC GO:0016021|GO:0052547 K08M4_RS18505 d11dd910b9f0194db400239fc3376c8a 465 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 462 1.3E-196 T 05-07-2017 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 K08M4_RS18505 d11dd910b9f0194db400239fc3376c8a 465 SUPERFAMILY SSF52467 292 463 7.27E-78 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain K08M4_RS18505 d11dd910b9f0194db400239fc3376c8a 465 Gene3D G3DSA:3.40.50.1220 290 465 1.6E-91 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain K08M4_RS18505 d11dd910b9f0194db400239fc3376c8a 465 PIRSF PIRSF000204 1 465 3.2E-233 T 05-07-2017 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 K08M4_RS14015 8c445bd9207e1c56cfe05e9cfcbeb710 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 6.8E-27 T 05-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS14015 8c445bd9207e1c56cfe05e9cfcbeb710 78 Pfam PF00830 Ribosomal L28 family 3 62 4.0E-26 T 05-07-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS14015 8c445bd9207e1c56cfe05e9cfcbeb710 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 21.292 T 05-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS14015 8c445bd9207e1c56cfe05e9cfcbeb710 78 Gene3D G3DSA:2.30.170.40 2 77 1.9E-35 T 05-07-2017 K08M4_RS14015 8c445bd9207e1c56cfe05e9cfcbeb710 78 SUPERFAMILY SSF143800 2 76 5.49E-30 T 05-07-2017 K08M4_RS16105 7e6396f8b191273596a30a67b59a465a 316 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 41 284 2.5E-59 T 05-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 K08M4_RS16105 7e6396f8b191273596a30a67b59a465a 316 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 13 296 22.862 T 05-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 K08M4_RS16105 7e6396f8b191273596a30a67b59a465a 316 PRINTS PR01755 Bacterial translocase SecF protein signature 153 167 4.6E-22 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS16105 7e6396f8b191273596a30a67b59a465a 316 PRINTS PR01755 Bacterial translocase SecF protein signature 233 248 4.6E-22 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS16105 7e6396f8b191273596a30a67b59a465a 316 PRINTS PR01755 Bacterial translocase SecF protein signature 40 55 4.6E-22 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS16105 7e6396f8b191273596a30a67b59a465a 316 PRINTS PR01755 Bacterial translocase SecF protein signature 201 219 4.6E-22 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS16105 7e6396f8b191273596a30a67b59a465a 316 Pfam PF02355 Protein export membrane protein 121 289 2.3E-53 T 05-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial K08M4_RS16105 7e6396f8b191273596a30a67b59a465a 316 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 115 282 9.7E-45 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS16105 7e6396f8b191273596a30a67b59a465a 316 SUPERFAMILY SSF82866 125 288 8.24E-31 T 05-07-2017 K08M4_RS16105 7e6396f8b191273596a30a67b59a465a 316 Gene3D G3DSA:1.20.1640.10 128 284 2.1E-25 T 05-07-2017 K08M4_RS16105 7e6396f8b191273596a30a67b59a465a 316 Pfam PF07549 SecD/SecF GG Motif 36 53 8.7E-5 T 05-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site K08M4_RS17090 345d64f4612da597f289ed5ff242fa1f 234 SMART SM00382 35 222 3.3E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS17090 345d64f4612da597f289ed5ff242fa1f 234 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS17090 345d64f4612da597f289ed5ff242fa1f 234 Gene3D G3DSA:3.40.50.300 6 227 1.5E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17090 345d64f4612da597f289ed5ff242fa1f 234 Pfam PF00005 ABC transporter 26 174 1.3E-32 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS17090 345d64f4612da597f289ed5ff242fa1f 234 SUPERFAMILY SSF52540 6 227 2.73E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21635 acbbd0e222bc074648fdbc4a39ecf3f0 492 SUPERFAMILY SSF55604 406 479 3.53E-19 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS21635 acbbd0e222bc074648fdbc4a39ecf3f0 492 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 419 436 - T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS21635 acbbd0e222bc074648fdbc4a39ecf3f0 492 Gene3D G3DSA:3.30.1360.60 403 480 6.5E-26 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS21635 acbbd0e222bc074648fdbc4a39ecf3f0 492 Pfam PF00367 phosphotransferase system, EIIB 409 440 3.6E-11 T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS21635 acbbd0e222bc074648fdbc4a39ecf3f0 492 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 382 466 1.6E-20 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS21635 acbbd0e222bc074648fdbc4a39ecf3f0 492 Pfam PF02378 Phosphotransferase system, EIIC 11 321 1.3E-73 T 05-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 K08M4_RS21635 acbbd0e222bc074648fdbc4a39ecf3f0 492 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 3 477 4.2E-179 T 05-07-2017 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 K08M4_RS01905 f0d5dae1664290d6715f27559cb61397 406 TIGRFAM TIGR01078 arcA: arginine deiminase 4 406 3.1E-169 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01905 f0d5dae1664290d6715f27559cb61397 406 PRINTS PR01466 Bacterial arginine deiminase signature 177 192 7.0E-44 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01905 f0d5dae1664290d6715f27559cb61397 406 PRINTS PR01466 Bacterial arginine deiminase signature 149 167 7.0E-44 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01905 f0d5dae1664290d6715f27559cb61397 406 PRINTS PR01466 Bacterial arginine deiminase signature 362 376 7.0E-44 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01905 f0d5dae1664290d6715f27559cb61397 406 PRINTS PR01466 Bacterial arginine deiminase signature 385 403 7.0E-44 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01905 f0d5dae1664290d6715f27559cb61397 406 PRINTS PR01466 Bacterial arginine deiminase signature 2 22 7.0E-44 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01905 f0d5dae1664290d6715f27559cb61397 406 PRINTS PR01466 Bacterial arginine deiminase signature 342 359 7.0E-44 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01905 f0d5dae1664290d6715f27559cb61397 406 Gene3D G3DSA:1.10.3930.10 68 136 2.3E-4 T 05-07-2017 K08M4_RS01905 f0d5dae1664290d6715f27559cb61397 406 Hamap MF_00242 Arginine deiminase [arcA]. 1 406 44.595 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS01905 f0d5dae1664290d6715f27559cb61397 406 Pfam PF02274 Amidinotransferase 19 403 2.6E-94 T 05-07-2017 K08M4_RS01905 f0d5dae1664290d6715f27559cb61397 406 Gene3D G3DSA:3.75.10.10 1 67 1.4E-124 T 05-07-2017 K08M4_RS01905 f0d5dae1664290d6715f27559cb61397 406 Gene3D G3DSA:3.75.10.10 149 406 1.4E-124 T 05-07-2017 K08M4_RS01905 f0d5dae1664290d6715f27559cb61397 406 SUPERFAMILY SSF55909 3 406 1.41E-126 T 05-07-2017 K08M4_RS01905 f0d5dae1664290d6715f27559cb61397 406 PIRSF PIRSF006356 1 406 6.9E-154 T 05-07-2017 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 K08M4_RS14105 1fd6515cf8248825450257d6363660da 527 SUPERFAMILY SSF55604 450 524 2.09E-18 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS14105 1fd6515cf8248825450257d6363660da 527 Pfam PF02378 Phosphotransferase system, EIIC 10 357 1.0E-55 T 05-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 K08M4_RS14105 1fd6515cf8248825450257d6363660da 527 Pfam PF00367 phosphotransferase system, EIIB 451 481 1.1E-15 T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS14105 1fd6515cf8248825450257d6363660da 527 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 461 478 - T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS14105 1fd6515cf8248825450257d6363660da 527 Gene3D G3DSA:3.30.1360.60 448 524 3.5E-23 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS14105 1fd6515cf8248825450257d6363660da 527 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 414 509 6.6E-19 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS07690 3ed29d7019ec214b6e990297a977ecfa 100 SUPERFAMILY SSF143011 1 90 9.42E-5 T 05-07-2017 K08M4_RS07690 3ed29d7019ec214b6e990297a977ecfa 100 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 91 3.9E-19 T 05-07-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family K08M4_RS14455 0a27aeb2d5bac86f08ae1435224f1177 1058 SMART SM00487 284 482 2.0E-4 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS14455 0a27aeb2d5bac86f08ae1435224f1177 1058 Pfam PF04851 Type III restriction enzyme, res subunit 286 459 9.8E-22 T 05-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 K08M4_RS14455 0a27aeb2d5bac86f08ae1435224f1177 1058 Gene3D G3DSA:3.40.50.300 281 460 2.4E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14455 0a27aeb2d5bac86f08ae1435224f1177 1058 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 4 179 1.5E-22 T 05-07-2017 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 K08M4_RS14455 0a27aeb2d5bac86f08ae1435224f1177 1058 SUPERFAMILY SSF52540 264 465 4.81E-21 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14455 0a27aeb2d5bac86f08ae1435224f1177 1058 SUPERFAMILY SSF52540 310 366 5.98E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14455 0a27aeb2d5bac86f08ae1435224f1177 1058 SUPERFAMILY SSF52540 618 724 5.98E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06005 d7c8430a6ccc15c30df182c4f631f40c 222 SUPERFAMILY SSF103088 106 221 2.35E-36 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS06005 d7c8430a6ccc15c30df182c4f631f40c 222 Pfam PF13488 Glycine zipper 38 86 5.7E-12 T 05-07-2017 K08M4_RS06005 d7c8430a6ccc15c30df182c4f631f40c 222 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 201 221 1.8E-5 T 05-07-2017 K08M4_RS06005 d7c8430a6ccc15c30df182c4f631f40c 222 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 181 200 1.8E-5 T 05-07-2017 K08M4_RS06005 d7c8430a6ccc15c30df182c4f631f40c 222 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 163 180 1.8E-5 T 05-07-2017 K08M4_RS06005 d7c8430a6ccc15c30df182c4f631f40c 222 Pfam PF00691 OmpA family 118 212 1.5E-21 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS06005 d7c8430a6ccc15c30df182c4f631f40c 222 Gene3D G3DSA:3.30.1330.60 107 220 8.7E-37 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS06005 d7c8430a6ccc15c30df182c4f631f40c 222 PRINTS PR01021 OMPA domain signature 118 140 5.1E-11 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS06005 d7c8430a6ccc15c30df182c4f631f40c 222 PRINTS PR01021 OMPA domain signature 148 163 5.1E-11 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS06005 d7c8430a6ccc15c30df182c4f631f40c 222 PRINTS PR01021 OMPA domain signature 163 179 5.1E-11 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS17670 469b0a20374d9fab1cddd8dcade71d2a 97 Pfam PF03692 Putative zinc- or iron-chelating domain 15 84 1.3E-9 T 05-07-2017 IPR005358 Putative zinc- or iron-chelating domain containing protein K08M4_RS05765 1acac6282e96ec977529892052639e8f 257 SUPERFAMILY SSF53850 1 252 2.1E-61 T 05-07-2017 K08M4_RS05765 1acac6282e96ec977529892052639e8f 257 SMART SM00062 23 251 4.6E-60 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS05765 1acac6282e96ec977529892052639e8f 257 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 24 249 2.8E-57 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS05765 1acac6282e96ec977529892052639e8f 257 Gene3D G3DSA:3.40.190.10 21 109 3.7E-42 T 05-07-2017 K08M4_RS05765 1acac6282e96ec977529892052639e8f 257 Gene3D G3DSA:3.40.190.10 210 253 3.7E-42 T 05-07-2017 K08M4_RS05765 1acac6282e96ec977529892052639e8f 257 Gene3D G3DSA:3.40.190.10 119 207 1.1E-20 T 05-07-2017 K08M4_RS05765 1acac6282e96ec977529892052639e8f 257 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 46 59 - T 05-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 K08M4_RS15765 a832a871a16149b89824a83cd8410245 392 SUPERFAMILY SSF53850 23 391 1.71E-90 T 05-07-2017 K08M4_RS15765 a832a871a16149b89824a83cd8410245 392 Pfam PF13416 Bacterial extracellular solute-binding protein 46 327 2.0E-45 T 05-07-2017 K08M4_RS15765 a832a871a16149b89824a83cd8410245 392 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 129 146 - T 05-07-2017 IPR006061 Solute-binding family 1, conserved site GO:0005215|GO:0006810 K08M4_RS15765 a832a871a16149b89824a83cd8410245 392 PRINTS PR00181 Maltose binding protein signature 66 84 1.8E-62 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS15765 a832a871a16149b89824a83cd8410245 392 PRINTS PR00181 Maltose binding protein signature 295 316 1.8E-62 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS15765 a832a871a16149b89824a83cd8410245 392 PRINTS PR00181 Maltose binding protein signature 147 166 1.8E-62 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS15765 a832a871a16149b89824a83cd8410245 392 PRINTS PR00181 Maltose binding protein signature 167 186 1.8E-62 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS15765 a832a871a16149b89824a83cd8410245 392 PRINTS PR00181 Maltose binding protein signature 353 372 1.8E-62 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS15765 a832a871a16149b89824a83cd8410245 392 PRINTS PR00181 Maltose binding protein signature 32 50 1.8E-62 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS15765 a832a871a16149b89824a83cd8410245 392 PRINTS PR00181 Maltose binding protein signature 126 145 1.8E-62 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS15765 a832a871a16149b89824a83cd8410245 392 PRINTS PR00181 Maltose binding protein signature 229 248 1.8E-62 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS15765 a832a871a16149b89824a83cd8410245 392 Gene3D G3DSA:3.40.190.10 136 317 1.4E-51 T 05-07-2017 K08M4_RS03955 9d28175524dd3f705ee8094d32ef0309 185 Pfam PF04279 Intracellular septation protein A 15 157 1.6E-8 T 05-07-2017 IPR006008 Intracellular septation protein A GO:0016021 K08M4_RS05200 6689f8f4c9868a89b3e3e4870f18fb3b 313 Pfam PF01584 CheW-like domain 21 160 1.6E-35 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS05200 6689f8f4c9868a89b3e3e4870f18fb3b 313 SUPERFAMILY SSF50341 16 161 4.71E-34 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS05200 6689f8f4c9868a89b3e3e4870f18fb3b 313 SMART SM00448 184 305 1.9E-11 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS05200 6689f8f4c9868a89b3e3e4870f18fb3b 313 SUPERFAMILY SSF52172 183 310 3.27E-21 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS05200 6689f8f4c9868a89b3e3e4870f18fb3b 313 Gene3D G3DSA:3.40.50.2300 183 310 9.9E-23 T 05-07-2017 K08M4_RS05200 6689f8f4c9868a89b3e3e4870f18fb3b 313 Pfam PF00072 Response regulator receiver domain 186 303 5.6E-14 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS05200 6689f8f4c9868a89b3e3e4870f18fb3b 313 SMART SM00260 17 158 3.6E-30 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS05200 6689f8f4c9868a89b3e3e4870f18fb3b 313 Gene3D G3DSA:2.40.50.180 60 96 1.0E-6 T 05-07-2017 K08M4_RS05200 6689f8f4c9868a89b3e3e4870f18fb3b 313 PIRSF PIRSF002867 1 312 6.5E-104 T 05-07-2017 IPR024181 Chemotaxis response regulator CheV K08M4_RS05200 6689f8f4c9868a89b3e3e4870f18fb3b 313 Gene3D G3DSA:2.30.30.40 97 137 1.4E-5 T 05-07-2017 K08M4_RS07455 beb1fbd743cfb0fceac790cf76892466 88 Pfam PF11173 Protein of unknown function (DUF2960) 1 77 9.0E-33 T 05-07-2017 IPR021343 Protein of unknown function DUF2960 K08M4_RS12450 3fe9869b48b8483096753d583215fd78 583 Pfam PF13188 PAS domain 39 78 0.0011 T 05-07-2017 IPR000014 PAS domain K08M4_RS12450 3fe9869b48b8483096753d583215fd78 583 Gene3D G3DSA:3.30.450.20 206 267 6.7E-4 T 05-07-2017 K08M4_RS12450 3fe9869b48b8483096753d583215fd78 583 Gene3D G3DSA:3.30.450.20 43 103 6.7E-4 T 05-07-2017 K08M4_RS12450 3fe9869b48b8483096753d583215fd78 583 SUPERFAMILY SSF55785 267 393 9.95E-19 T 05-07-2017 IPR000014 PAS domain K08M4_RS12450 3fe9869b48b8483096753d583215fd78 583 Gene3D G3DSA:3.30.450.20 268 393 3.7E-19 T 05-07-2017 K08M4_RS12450 3fe9869b48b8483096753d583215fd78 583 SMART SM00091 158 235 210.0 T 05-07-2017 IPR000014 PAS domain K08M4_RS12450 3fe9869b48b8483096753d583215fd78 583 SMART SM00091 38 104 4.4 T 05-07-2017 IPR000014 PAS domain K08M4_RS12450 3fe9869b48b8483096753d583215fd78 583 SMART SM00091 280 347 0.17 T 05-07-2017 IPR000014 PAS domain K08M4_RS12450 3fe9869b48b8483096753d583215fd78 583 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 409 577 5.3E-48 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS12450 3fe9869b48b8483096753d583215fd78 583 SUPERFAMILY SSF55073 418 577 3.84E-45 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS12450 3fe9869b48b8483096753d583215fd78 583 Pfam PF00990 Diguanylate cyclase, GGDEF domain 414 574 8.1E-50 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS12450 3fe9869b48b8483096753d583215fd78 583 Pfam PF08448 PAS fold 286 396 2.2E-15 T 05-07-2017 IPR013656 PAS fold-4 K08M4_RS12450 3fe9869b48b8483096753d583215fd78 583 Gene3D G3DSA:3.30.70.270 415 577 1.3E-48 T 05-07-2017 K08M4_RS12450 3fe9869b48b8483096753d583215fd78 583 SMART SM00267 402 578 2.4E-69 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS12450 3fe9869b48b8483096753d583215fd78 583 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 277 402 1.2E-13 T 05-07-2017 IPR000014 PAS domain K08M4_RS20015 0f0bd7f752e3ca66ea665a6793b0ac14 339 TIGRFAM TIGR01540 portal_PBSX: phage portal protein, PBSX family 49 323 3.9E-64 T 05-07-2017 IPR006430 Phage portal protein PBSX family K08M4_RS20015 0f0bd7f752e3ca66ea665a6793b0ac14 339 PIRSF PIRSF018494 1 338 1.6E-125 T 05-07-2017 IPR030935 Phage portal protein PBSX family, Proteobacteria K08M4_RS20015 0f0bd7f752e3ca66ea665a6793b0ac14 339 Pfam PF04860 Phage portal protein 94 337 2.1E-8 T 05-07-2017 IPR006944 Bacteriophage/Gene transfer agent portal protein K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 SUPERFAMILY SSF88659 510 612 1.91E-25 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 376 612 2.0E-120 T 05-07-2017 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 Pfam PF03979 Sigma-70 factor, region 1.1 4 80 4.8E-28 T 05-07-2017 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 Gene3D G3DSA:1.10.10.10 453 504 1.3E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 Pfam PF04545 Sigma-70, region 4 548 601 1.5E-19 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 Gene3D G3DSA:1.10.601.10 112 449 4.9E-130 T 05-07-2017 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 SUPERFAMILY SSF88659 453 526 2.2E-20 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 Pfam PF04546 Sigma-70, non-essential region 139 349 5.8E-63 T 05-07-2017 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 Pfam PF04542 Sigma-70 region 2 380 449 1.7E-21 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 404 417 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 376 601 1.5E-37 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 Gene3D G3DSA:1.10.10.10 544 613 4.2E-33 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 4 613 45.682 T 05-07-2017 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 PRINTS PR00046 Major sigma-70 factor signature 404 417 3.0E-31 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 PRINTS PR00046 Major sigma-70 factor signature 428 436 3.0E-31 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 PRINTS PR00046 Major sigma-70 factor signature 552 564 3.0E-31 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 PRINTS PR00046 Major sigma-70 factor signature 573 588 3.0E-31 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 PRINTS PR00046 Major sigma-70 factor signature 588 599 3.0E-31 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 573 599 - T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 Pfam PF04539 Sigma-70 region 3 459 534 1.3E-28 T 05-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 Pfam PF00140 Sigma-70 factor, region 1.2 98 128 1.7E-12 T 05-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS12835 632e2d9b7314a2cd68cc3132bf84e799 614 SUPERFAMILY SSF88946 115 447 6.95E-93 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS21875 740af88303a84701f36457e7d587b7f6 310 Gene3D G3DSA:3.40.50.300 2 259 3.3E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21875 740af88303a84701f36457e7d587b7f6 310 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 267 4.5E-8 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS21875 740af88303a84701f36457e7d587b7f6 310 SMART SM00382 39 233 9.7E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS21875 740af88303a84701f36457e7d587b7f6 310 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS21875 740af88303a84701f36457e7d587b7f6 310 SUPERFAMILY SSF52540 6 254 9.41E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21875 740af88303a84701f36457e7d587b7f6 310 Pfam PF00005 ABC transporter 30 184 4.1E-33 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS13935 75bb50299e2ca165b5f4e3b1b717658a 317 PIRSF PIRSF026649 12 314 6.0E-87 T 05-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 K08M4_RS13935 75bb50299e2ca165b5f4e3b1b717658a 317 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 15 306 1.1E-81 T 05-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 K08M4_RS13935 75bb50299e2ca165b5f4e3b1b717658a 317 Hamap MF_01944 Lipid A biosynthesis myristoyltransferase [lpxM]. 7 311 48.924 T 05-07-2017 IPR011921 Lipid A biosynthesis myristoyltransferase GO:0009103|GO:0009276|GO:0016021|GO:0016747 KEGG: 00540+2.3.1.243|KEGG: 00600+2.3.1.24 K08M4_RS13935 75bb50299e2ca165b5f4e3b1b717658a 317 TIGRFAM TIGR02208 lipid_A_msbB: lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 13 314 2.4E-115 T 05-07-2017 IPR011921 Lipid A biosynthesis myristoyltransferase GO:0009103|GO:0009276|GO:0016021|GO:0016747 KEGG: 00540+2.3.1.243|KEGG: 00600+2.3.1.24 K08M4_RS21390 b5365ad6bdd477fa15faf33d3becdcda 93 SUPERFAMILY SSF51182 1 93 5.25E-33 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS21390 b5365ad6bdd477fa15faf33d3becdcda 93 Pfam PF06865 Protein of unknown function (DUF1255) 3 92 8.2E-33 T 05-07-2017 IPR009664 Protein of unknown function DUF1255 K08M4_RS21390 b5365ad6bdd477fa15faf33d3becdcda 93 Gene3D G3DSA:2.60.120.10 1 93 1.6E-36 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS21390 b5365ad6bdd477fa15faf33d3becdcda 93 Hamap MF_01537 UPF0345 protein YaiE [yaiE]. 1 93 24.639 T 05-07-2017 IPR009664 Protein of unknown function DUF1255 K08M4_RS09150 04d2e99a472d229d4164215156ab02d7 975 Pfam PF00202 Aminotransferase class-III 52 465 7.6E-94 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 K08M4_RS09150 04d2e99a472d229d4164215156ab02d7 975 SUPERFAMILY SSF53383 510 969 1.55E-111 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS09150 04d2e99a472d229d4164215156ab02d7 975 Gene3D G3DSA:1.20.1650.10 475 566 2.2E-34 T 05-07-2017 K08M4_RS09150 04d2e99a472d229d4164215156ab02d7 975 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 35 467 2.0E-156 T 05-07-2017 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 K08M4_RS09150 04d2e99a472d229d4164215156ab02d7 975 SUPERFAMILY SSF53383 42 465 8.87E-114 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS09150 04d2e99a472d229d4164215156ab02d7 975 Gene3D G3DSA:3.40.640.10 577 850 2.5E-90 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS09150 04d2e99a472d229d4164215156ab02d7 975 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 785 806 - T 05-07-2017 IPR021115 Pyridoxal-phosphate binding site GO:0016831 K08M4_RS09150 04d2e99a472d229d4164215156ab02d7 975 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 547 897 3.2E-61 T 05-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 K08M4_RS09150 04d2e99a472d229d4164215156ab02d7 975 Gene3D G3DSA:3.40.640.10 89 339 3.1E-68 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS09150 04d2e99a472d229d4164215156ab02d7 975 Gene3D G3DSA:3.90.1150.10 851 970 3.4E-40 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS09150 04d2e99a472d229d4164215156ab02d7 975 Gene3D G3DSA:3.90.1150.10 340 465 2.6E-40 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS11700 8f4bb735ac35406970a16050b757648a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 359 379 1.6E-36 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS11700 8f4bb735ac35406970a16050b757648a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 3 23 1.6E-36 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS11700 8f4bb735ac35406970a16050b757648a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 195 214 1.6E-36 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS11700 8f4bb735ac35406970a16050b757648a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 297 323 1.6E-36 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS11700 8f4bb735ac35406970a16050b757648a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 1.6E-36 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS11700 8f4bb735ac35406970a16050b757648a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 332 351 1.6E-36 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS11700 8f4bb735ac35406970a16050b757648a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 51 71 1.6E-36 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS11700 8f4bb735ac35406970a16050b757648a 424 PRINTS PR00173 Glutamate-aspartate symporter signature 148 170 1.6E-36 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS11700 8f4bb735ac35406970a16050b757648a 424 Pfam PF00375 Sodium:dicarboxylate symporter family 6 404 4.0E-115 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS11700 8f4bb735ac35406970a16050b757648a 424 SUPERFAMILY SSF118215 5 406 1.31E-105 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS11700 8f4bb735ac35406970a16050b757648a 424 Gene3D G3DSA:1.10.3860.10 3 407 2.1E-108 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS19460 3643857b8bd4ff2f8cd2c55b55344686 314 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 5 304 1.5E-106 T 05-07-2017 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 K08M4_RS19460 3643857b8bd4ff2f8cd2c55b55344686 314 Gene3D G3DSA:3.40.1190.20 2 310 4.9E-97 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS19460 3643857b8bd4ff2f8cd2c55b55344686 314 SUPERFAMILY SSF53613 1 308 2.18E-84 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS19460 3643857b8bd4ff2f8cd2c55b55344686 314 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 252 265 - T 05-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 K08M4_RS19460 3643857b8bd4ff2f8cd2c55b55344686 314 PRINTS PR00990 Ribokinase signature 105 118 8.6E-35 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 K08M4_RS19460 3643857b8bd4ff2f8cd2c55b55344686 314 PRINTS PR00990 Ribokinase signature 33 52 8.6E-35 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 K08M4_RS19460 3643857b8bd4ff2f8cd2c55b55344686 314 PRINTS PR00990 Ribokinase signature 173 188 8.6E-35 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 K08M4_RS19460 3643857b8bd4ff2f8cd2c55b55344686 314 PRINTS PR00990 Ribokinase signature 217 228 8.6E-35 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 K08M4_RS19460 3643857b8bd4ff2f8cd2c55b55344686 314 PRINTS PR00990 Ribokinase signature 6 27 8.6E-35 T 05-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 K08M4_RS19460 3643857b8bd4ff2f8cd2c55b55344686 314 Hamap MF_01987 Ribokinase [rbsK]. 2 307 25.721 T 05-07-2017 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 K08M4_RS19460 3643857b8bd4ff2f8cd2c55b55344686 314 Pfam PF00294 pfkB family carbohydrate kinase 1 300 3.5E-72 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB K08M4_RS05300 f82c32a72101384c554f941d17a665f2 721 SUPERFAMILY SSF53474 455 699 2.2E-39 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS05300 f82c32a72101384c554f941d17a665f2 721 Gene3D G3DSA:2.130.10.120 111 447 9.7E-100 T 05-07-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 K08M4_RS05300 f82c32a72101384c554f941d17a665f2 721 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 42 443 4.9E-97 T 05-07-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 K08M4_RS05300 f82c32a72101384c554f941d17a665f2 721 Pfam PF00326 Prolyl oligopeptidase family 505 719 8.7E-69 T 05-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 K08M4_RS05300 f82c32a72101384c554f941d17a665f2 721 Gene3D G3DSA:3.40.50.1820 457 699 2.8E-31 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS05300 f82c32a72101384c554f941d17a665f2 721 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 572 592 3.0E-50 T 05-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 K08M4_RS05300 f82c32a72101384c554f941d17a665f2 721 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 488 506 3.0E-50 T 05-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 K08M4_RS05300 f82c32a72101384c554f941d17a665f2 721 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 648 670 3.0E-50 T 05-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 K08M4_RS05300 f82c32a72101384c554f941d17a665f2 721 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 514 538 3.0E-50 T 05-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 K08M4_RS05300 f82c32a72101384c554f941d17a665f2 721 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 630 645 3.0E-50 T 05-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 K08M4_RS05300 f82c32a72101384c554f941d17a665f2 721 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 542 561 3.0E-50 T 05-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 K08M4_RS05300 f82c32a72101384c554f941d17a665f2 721 SUPERFAMILY SSF50993 39 450 1.12E-94 T 05-07-2017 K08M4_RS12865 1b159bcf1754cc1664755bf4996911cb 223 SUPERFAMILY SSF48008 78 219 3.66E-14 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS12865 1b159bcf1754cc1664755bf4996911cb 223 SMART SM00895 82 211 1.8E-4 T 05-07-2017 IPR011711 GntR, C-terminal K08M4_RS12865 1b159bcf1754cc1664755bf4996911cb 223 SMART SM00345 14 72 3.8E-9 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS12865 1b159bcf1754cc1664755bf4996911cb 223 Pfam PF07729 FCD domain 82 209 3.3E-16 T 05-07-2017 IPR011711 GntR, C-terminal K08M4_RS12865 1b159bcf1754cc1664755bf4996911cb 223 SUPERFAMILY SSF46785 5 76 4.67E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS12865 1b159bcf1754cc1664755bf4996911cb 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 3.3E-15 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS12865 1b159bcf1754cc1664755bf4996911cb 223 Gene3D G3DSA:1.20.120.530 76 221 8.4E-26 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS12865 1b159bcf1754cc1664755bf4996911cb 223 Gene3D G3DSA:1.10.10.10 6 74 5.0E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS07860 d9c4e07d06c0e2b29646dd44627e765e 473 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 186 197 - T 05-07-2017 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS07860 d9c4e07d06c0e2b29646dd44627e765e 473 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 291 308 2.7E-27 T 05-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS07860 d9c4e07d06c0e2b29646dd44627e765e 473 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 237 253 2.7E-27 T 05-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS07860 d9c4e07d06c0e2b29646dd44627e765e 473 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 120 130 2.7E-27 T 05-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS07860 d9c4e07d06c0e2b29646dd44627e765e 473 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 187 199 2.7E-27 T 05-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS07860 d9c4e07d06c0e2b29646dd44627e765e 473 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 89 103 2.7E-27 T 05-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS07860 d9c4e07d06c0e2b29646dd44627e765e 473 Hamap MF_01579 Ribosomal RNA small subunit methyltransferase F [rsmF]. 5 473 65.038 T 05-07-2017 IPR023545 rRNA small subunit methyltransferase F GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS07860 d9c4e07d06c0e2b29646dd44627e765e 473 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 40 308 8.1E-99 T 05-07-2017 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901 K08M4_RS07860 d9c4e07d06c0e2b29646dd44627e765e 473 Gene3D G3DSA:3.40.50.150 100 308 3.8E-55 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS07860 d9c4e07d06c0e2b29646dd44627e765e 473 SUPERFAMILY SSF53335 7 308 6.15E-60 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS07860 d9c4e07d06c0e2b29646dd44627e765e 473 Pfam PF01189 16S rRNA methyltransferase RsmB/F 116 306 1.5E-48 T 05-07-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS07860 d9c4e07d06c0e2b29646dd44627e765e 473 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 419 468 2.2E-11 T 05-07-2017 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS07860 d9c4e07d06c0e2b29646dd44627e765e 473 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 7 103 1.5E-28 T 05-07-2017 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901 K08M4_RS05525 3652f847603606bdfdd00f5592f76a8f 203 Gene3D G3DSA:1.10.8.10 157 203 2.9E-24 T 05-07-2017 K08M4_RS05525 3652f847603606bdfdd00f5592f76a8f 203 Pfam PF14520 Helix-hairpin-helix domain 72 130 3.0E-14 T 05-07-2017 K08M4_RS05525 3652f847603606bdfdd00f5592f76a8f 203 SUPERFAMILY SSF47781 66 136 1.56E-19 T 05-07-2017 IPR010994 RuvA domain 2-like K08M4_RS05525 3652f847603606bdfdd00f5592f76a8f 203 Pfam PF07499 RuvA, C-terminal domain 158 202 2.7E-17 T 05-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 K08M4_RS05525 3652f847603606bdfdd00f5592f76a8f 203 Gene3D G3DSA:1.10.150.20 67 142 7.0E-29 T 05-07-2017 K08M4_RS05525 3652f847603606bdfdd00f5592f76a8f 203 Pfam PF01330 RuvA N terminal domain 2 62 7.5E-21 T 05-07-2017 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 K08M4_RS05525 3652f847603606bdfdd00f5592f76a8f 203 SMART SM00278 108 127 0.071 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 K08M4_RS05525 3652f847603606bdfdd00f5592f76a8f 203 SMART SM00278 73 92 540.0 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 K08M4_RS05525 3652f847603606bdfdd00f5592f76a8f 203 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 203 31.713 T 05-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 K08M4_RS05525 3652f847603606bdfdd00f5592f76a8f 203 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 202 8.5E-64 T 05-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 K08M4_RS05525 3652f847603606bdfdd00f5592f76a8f 203 SUPERFAMILY SSF50249 2 63 9.14E-19 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS05525 3652f847603606bdfdd00f5592f76a8f 203 SUPERFAMILY SSF46929 158 202 2.62E-12 T 05-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 K08M4_RS05525 3652f847603606bdfdd00f5592f76a8f 203 Gene3D G3DSA:2.40.50.140 2 65 2.5E-28 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS17590 d4e7b26632ae991544f503d787dee9f2 382 Gene3D G3DSA:3.40.50.1970 1 180 4.4E-57 T 05-07-2017 K08M4_RS17590 d4e7b26632ae991544f503d787dee9f2 382 SUPERFAMILY SSF56796 3 380 4.58E-96 T 05-07-2017 K08M4_RS17590 d4e7b26632ae991544f503d787dee9f2 382 Gene3D G3DSA:1.20.1090.10 181 381 2.2E-36 T 05-07-2017 K08M4_RS17590 d4e7b26632ae991544f503d787dee9f2 382 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 353 6.6E-79 T 05-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 K08M4_RS01470 c0e5847c92961a35589161572d19f9fd 200 Pfam PF00573 Ribosomal protein L4/L1 family 12 197 1.9E-65 T 05-07-2017 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 K08M4_RS01470 c0e5847c92961a35589161572d19f9fd 200 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 12 197 1.7E-75 T 05-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01470 c0e5847c92961a35589161572d19f9fd 200 SUPERFAMILY SSF52166 9 199 3.01E-73 T 05-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 K08M4_RS01470 c0e5847c92961a35589161572d19f9fd 200 Gene3D G3DSA:3.40.1370.10 52 200 2.2E-59 T 05-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 K08M4_RS01470 c0e5847c92961a35589161572d19f9fd 200 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 6 200 33.74 T 05-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS03615 291fb14479fe03fc186868fc60a942a6 630 SUPERFAMILY SSF56601 255 619 4.4E-93 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS03615 291fb14479fe03fc186868fc60a942a6 630 Gene3D G3DSA:3.40.710.10 255 619 3.8E-101 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS03615 291fb14479fe03fc186868fc60a942a6 630 Pfam PF00905 Penicillin binding protein transpeptidase domain 272 616 1.2E-75 T 05-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 K08M4_RS03615 291fb14479fe03fc186868fc60a942a6 630 SUPERFAMILY SSF56519 57 253 1.03E-53 T 05-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 K08M4_RS03615 291fb14479fe03fc186868fc60a942a6 630 Gene3D G3DSA:3.90.1310.10 131 253 4.9E-37 T 05-07-2017 K08M4_RS03615 291fb14479fe03fc186868fc60a942a6 630 Pfam PF03717 Penicillin-binding Protein dimerisation domain 65 240 3.9E-48 T 05-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 K08M4_RS03615 291fb14479fe03fc186868fc60a942a6 630 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 21 619 7.6E-237 T 05-07-2017 IPR017790 Penicillin-binding protein 2 GO:0016020 K08M4_RS09795 90b297645ef913d07491bdfaf8b1b9ad 59 SUPERFAMILY SSF158997 1 54 2.88E-20 T 05-07-2017 K08M4_RS09795 90b297645ef913d07491bdfaf8b1b9ad 59 Gene3D G3DSA:2.20.25.10 8 57 7.8E-25 T 05-07-2017 K08M4_RS09795 90b297645ef913d07491bdfaf8b1b9ad 59 Pfam PF03966 Trm112p-like protein 2 41 2.2E-11 T 05-07-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 K08M4_RS09795 90b297645ef913d07491bdfaf8b1b9ad 59 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 27.799 T 05-07-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 K08M4_RS09770 3b0e2c42ee82f6ec270e9cbb2ae58cc4 90 Hamap MF_01948 Lipopolysaccharide assembly protein A [lapA]. 1 89 18.856 T 05-07-2017 IPR032906 Lipopolysaccharide assembly protein A GO:0005886|GO:0008653 K08M4_RS09770 3b0e2c42ee82f6ec270e9cbb2ae58cc4 90 Pfam PF06305 Protein of unknown function (DUF1049) 22 84 2.4E-17 T 05-07-2017 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 K08M4_RS19530 612579799bd6cda7b19aac93255dffef 489 Pfam PF07690 Major Facilitator Superfamily 302 470 5.2E-14 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS19530 612579799bd6cda7b19aac93255dffef 489 Pfam PF07690 Major Facilitator Superfamily 22 216 1.5E-21 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS19530 612579799bd6cda7b19aac93255dffef 489 Gene3D G3DSA:1.20.1250.20 16 199 1.0E-26 T 05-07-2017 K08M4_RS19530 612579799bd6cda7b19aac93255dffef 489 SUPERFAMILY SSF103473 10 208 4.71E-58 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS19530 612579799bd6cda7b19aac93255dffef 489 SUPERFAMILY SSF103473 266 466 4.71E-58 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS19530 612579799bd6cda7b19aac93255dffef 489 TIGRFAM TIGR00886 2A0108: nitrite transporter 16 433 6.0E-100 T 05-07-2017 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 K08M4_RS19530 612579799bd6cda7b19aac93255dffef 489 Gene3D G3DSA:1.20.1250.20 291 471 2.6E-28 T 05-07-2017 K08M4_RS19530 612579799bd6cda7b19aac93255dffef 489 ProSitePatterns PS00216 Sugar transport proteins signature 1. 349 366 - T 05-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 K08M4_RS05445 97eb9366d4535e557a047c47a3595ea8 215 SUPERFAMILY SSF89155 8 212 1.7E-50 T 05-07-2017 IPR020945 DMSO/Nitrate reductase chaperone K08M4_RS05445 97eb9366d4535e557a047c47a3595ea8 215 Hamap MF_01150 Chaperone protein TorD [torD]. 3 212 33.77 T 05-07-2017 IPR023069 Chaperone TorD K08M4_RS05445 97eb9366d4535e557a047c47a3595ea8 215 Gene3D G3DSA:1.10.3480.10 71 213 5.9E-49 T 05-07-2017 IPR020945 DMSO/Nitrate reductase chaperone K08M4_RS05445 97eb9366d4535e557a047c47a3595ea8 215 Gene3D G3DSA:1.10.3480.10 7 32 5.9E-49 T 05-07-2017 IPR020945 DMSO/Nitrate reductase chaperone K08M4_RS05445 97eb9366d4535e557a047c47a3595ea8 215 Pfam PF02613 Nitrate reductase delta subunit 52 181 3.3E-37 T 05-07-2017 IPR020945 DMSO/Nitrate reductase chaperone K08M4_RS18890 9ee08c7fc8c75fdf5001b3875fd7e07a 407 Pfam PF03222 Tryptophan/tyrosine permease family 4 394 1.6E-108 T 05-07-2017 IPR018227 Tryptophan/tyrosine permease GO:0003333 K08M4_RS18890 9ee08c7fc8c75fdf5001b3875fd7e07a 407 ProSitePatterns PS00594 Aromatic amino acids permeases signature. 18 34 - T 05-07-2017 IPR013061 Tryptophan/tryrosine permease, conserved site K08M4_RS18890 9ee08c7fc8c75fdf5001b3875fd7e07a 407 PRINTS PR00166 Aromatic amino acid permease signature 38 57 1.2E-80 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS18890 9ee08c7fc8c75fdf5001b3875fd7e07a 407 PRINTS PR00166 Aromatic amino acid permease signature 83 103 1.2E-80 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS18890 9ee08c7fc8c75fdf5001b3875fd7e07a 407 PRINTS PR00166 Aromatic amino acid permease signature 334 353 1.2E-80 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS18890 9ee08c7fc8c75fdf5001b3875fd7e07a 407 PRINTS PR00166 Aromatic amino acid permease signature 11 34 1.2E-80 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS18890 9ee08c7fc8c75fdf5001b3875fd7e07a 407 PRINTS PR00166 Aromatic amino acid permease signature 149 169 1.2E-80 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS18890 9ee08c7fc8c75fdf5001b3875fd7e07a 407 PRINTS PR00166 Aromatic amino acid permease signature 183 205 1.2E-80 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS18890 9ee08c7fc8c75fdf5001b3875fd7e07a 407 PRINTS PR00166 Aromatic amino acid permease signature 222 241 1.2E-80 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS18890 9ee08c7fc8c75fdf5001b3875fd7e07a 407 PRINTS PR00166 Aromatic amino acid permease signature 313 331 1.2E-80 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS18890 9ee08c7fc8c75fdf5001b3875fd7e07a 407 PRINTS PR00166 Aromatic amino acid permease signature 279 298 1.2E-80 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS18890 9ee08c7fc8c75fdf5001b3875fd7e07a 407 TIGRFAM TIGR00837 araaP: aromatic amino acid transport protein 8 383 1.6E-110 T 05-07-2017 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 K08M4_RS06350 e6b48c24903f685a8b4479d19ec67c81 269 Pfam PF01925 Sulfite exporter TauE/SafE 12 266 1.2E-51 T 05-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 K08M4_RS21280 3de65bbe2f9a557195f9f60e5c999d46 686 Pfam PF00326 Prolyl oligopeptidase family 464 679 6.6E-66 T 05-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 K08M4_RS21280 3de65bbe2f9a557195f9f60e5c999d46 686 Gene3D G3DSA:2.130.10.120 77 409 4.2E-93 T 05-07-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 K08M4_RS21280 3de65bbe2f9a557195f9f60e5c999d46 686 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 10 406 9.7E-118 T 05-07-2017 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 K08M4_RS21280 3de65bbe2f9a557195f9f60e5c999d46 686 SUPERFAMILY SSF50993 6 413 2.56E-90 T 05-07-2017 K08M4_RS21280 3de65bbe2f9a557195f9f60e5c999d46 686 Gene3D G3DSA:3.40.50.1820 416 673 8.8E-45 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS21280 3de65bbe2f9a557195f9f60e5c999d46 686 SUPERFAMILY SSF53474 418 659 4.01E-48 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS21280 3de65bbe2f9a557195f9f60e5c999d46 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 608 630 6.1E-59 T 05-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 K08M4_RS21280 3de65bbe2f9a557195f9f60e5c999d46 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 475 499 6.1E-59 T 05-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 K08M4_RS21280 3de65bbe2f9a557195f9f60e5c999d46 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 589 604 6.1E-59 T 05-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 K08M4_RS21280 3de65bbe2f9a557195f9f60e5c999d46 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 533 553 6.1E-59 T 05-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 K08M4_RS21280 3de65bbe2f9a557195f9f60e5c999d46 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 449 467 6.1E-59 T 05-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 K08M4_RS21280 3de65bbe2f9a557195f9f60e5c999d46 686 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 503 522 6.1E-59 T 05-07-2017 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 K08M4_RS21280 3de65bbe2f9a557195f9f60e5c999d46 686 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 510 540 - T 05-07-2017 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 K08M4_RS01310 cdeb978f0d72adae78d84bfa801d35da 338 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 334 1.5E-106 T 05-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 K08M4_RS01310 cdeb978f0d72adae78d84bfa801d35da 338 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 335 40.033 T 05-07-2017 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 K08M4_RS01310 cdeb978f0d72adae78d84bfa801d35da 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 66 85 5.1E-26 T 05-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 K08M4_RS01310 cdeb978f0d72adae78d84bfa801d35da 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 198 208 5.1E-26 T 05-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 K08M4_RS01310 cdeb978f0d72adae78d84bfa801d35da 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 142 163 5.1E-26 T 05-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 K08M4_RS01310 cdeb978f0d72adae78d84bfa801d35da 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 5.1E-26 T 05-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 K08M4_RS01310 cdeb978f0d72adae78d84bfa801d35da 338 Pfam PF00579 tRNA synthetases class I (W and Y) 3 289 7.4E-75 T 05-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS01310 cdeb978f0d72adae78d84bfa801d35da 338 Gene3D G3DSA:1.10.240.10 209 327 9.3E-18 T 05-07-2017 K08M4_RS01310 cdeb978f0d72adae78d84bfa801d35da 338 SUPERFAMILY SSF52374 5 334 1.09E-89 T 05-07-2017 K08M4_RS01310 cdeb978f0d72adae78d84bfa801d35da 338 Gene3D G3DSA:3.40.50.620 4 208 4.2E-85 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS21285 cb141754c6d510c22943f22956427e15 305 SUPERFAMILY SSF46785 1 87 5.53E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21285 cb141754c6d510c22943f22956427e15 305 Gene3D G3DSA:3.40.190.10 89 166 8.4E-5 T 05-07-2017 K08M4_RS21285 cb141754c6d510c22943f22956427e15 305 Pfam PF03466 LysR substrate binding domain 88 297 1.4E-39 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS21285 cb141754c6d510c22943f22956427e15 305 Gene3D G3DSA:3.40.190.10 167 265 5.9E-21 T 05-07-2017 K08M4_RS21285 cb141754c6d510c22943f22956427e15 305 SUPERFAMILY SSF53850 88 298 3.8E-42 T 05-07-2017 K08M4_RS21285 cb141754c6d510c22943f22956427e15 305 Gene3D G3DSA:1.10.10.10 1 85 1.4E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21285 cb141754c6d510c22943f22956427e15 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 5.8E-18 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS07625 61e6850b4ac5181d2cb26b72e8e1ce1c 248 SUPERFAMILY SSF51206 23 162 1.44E-31 T 05-07-2017 IPR018490 Cyclic nucleotide-binding-like K08M4_RS07625 61e6850b4ac5181d2cb26b72e8e1ce1c 248 Gene3D G3DSA:2.60.120.10 18 169 3.2E-41 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS07625 61e6850b4ac5181d2cb26b72e8e1ce1c 248 SUPERFAMILY SSF46785 165 244 7.32E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS07625 61e6850b4ac5181d2cb26b72e8e1ce1c 248 SMART SM00419 187 235 1.5E-13 T 05-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 K08M4_RS07625 61e6850b4ac5181d2cb26b72e8e1ce1c 248 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 193 209 4.7E-11 T 05-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 K08M4_RS07625 61e6850b4ac5181d2cb26b72e8e1ce1c 248 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 209 224 4.7E-11 T 05-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 K08M4_RS07625 61e6850b4ac5181d2cb26b72e8e1ce1c 248 Gene3D G3DSA:1.10.10.10 170 244 3.4E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS07625 61e6850b4ac5181d2cb26b72e8e1ce1c 248 SMART SM00100 30 151 2.3E-20 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain K08M4_RS07625 61e6850b4ac5181d2cb26b72e8e1ce1c 248 ProSitePatterns PS00042 Crp-type HTH domain signature. 195 218 - T 05-07-2017 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 K08M4_RS07625 61e6850b4ac5181d2cb26b72e8e1ce1c 248 Pfam PF13545 Crp-like helix-turn-helix domain 168 241 2.1E-17 T 05-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 K08M4_RS07625 61e6850b4ac5181d2cb26b72e8e1ce1c 248 Pfam PF00027 Cyclic nucleotide-binding domain 51 132 5.5E-15 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain K08M4_RS11175 7c67127087279ed2a45dbba06ee655be 343 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 130 158 - T 05-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 K08M4_RS11175 7c67127087279ed2a45dbba06ee655be 343 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 5 326 34.575 T 05-07-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 K08M4_RS11175 7c67127087279ed2a45dbba06ee655be 343 Gene3D G3DSA:2.160.10.10 96 139 2.2E-11 T 05-07-2017 K08M4_RS11175 7c67127087279ed2a45dbba06ee655be 343 Gene3D G3DSA:2.160.10.10 140 309 2.9E-38 T 05-07-2017 K08M4_RS11175 7c67127087279ed2a45dbba06ee655be 343 SUPERFAMILY SSF51161 32 316 1.6E-82 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS11175 7c67127087279ed2a45dbba06ee655be 343 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 100 128 - T 05-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 K08M4_RS11175 7c67127087279ed2a45dbba06ee655be 343 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 222 257 6.7E-4 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS11175 7c67127087279ed2a45dbba06ee655be 343 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 145 179 2.5E-6 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS11175 7c67127087279ed2a45dbba06ee655be 343 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 143 2.6E-10 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS11175 7c67127087279ed2a45dbba06ee655be 343 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 259 285 0.21 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS11175 7c67127087279ed2a45dbba06ee655be 343 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 8 329 2.2E-115 T 05-07-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 K08M4_RS11175 7c67127087279ed2a45dbba06ee655be 343 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 23 88 3.1E-21 T 05-07-2017 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 K08M4_RS05520 582339fc82b3854697247750e96baa7f 173 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 4 150 6.9E-60 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 K08M4_RS05520 582339fc82b3854697247750e96baa7f 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 1.5E-40 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 K08M4_RS05520 582339fc82b3854697247750e96baa7f 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 1.5E-40 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 K08M4_RS05520 582339fc82b3854697247750e96baa7f 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 1.5E-40 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 K08M4_RS05520 582339fc82b3854697247750e96baa7f 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 1.5E-40 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 K08M4_RS05520 582339fc82b3854697247750e96baa7f 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 5 18 1.5E-40 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 K08M4_RS05520 582339fc82b3854697247750e96baa7f 173 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 155 3.6E-72 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 K08M4_RS05520 582339fc82b3854697247750e96baa7f 173 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 2 153 45.258 T 05-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 K08M4_RS05520 582339fc82b3854697247750e96baa7f 173 Gene3D G3DSA:3.30.420.10 3 156 1.8E-64 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS05520 582339fc82b3854697247750e96baa7f 173 SUPERFAMILY SSF53098 3 156 8.09E-53 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS15655 ab563d5679ace7ee03e86b56ee236100 251 Pfam PF00455 DeoR C terminal sensor domain 77 230 1.5E-39 T 05-07-2017 IPR014036 DeoR C-terminal sensor domain K08M4_RS15655 ab563d5679ace7ee03e86b56ee236100 251 SMART SM01134 74 232 1.0E-42 T 05-07-2017 K08M4_RS15655 ab563d5679ace7ee03e86b56ee236100 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 05-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 K08M4_RS15655 ab563d5679ace7ee03e86b56ee236100 251 Gene3D G3DSA:1.10.10.10 2 55 2.0E-6 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15655 ab563d5679ace7ee03e86b56ee236100 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 1.0E-13 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 K08M4_RS15655 ab563d5679ace7ee03e86b56ee236100 251 SUPERFAMILY SSF46785 5 63 2.43E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15655 ab563d5679ace7ee03e86b56ee236100 251 SUPERFAMILY SSF100950 75 234 3.24E-24 T 05-07-2017 K08M4_RS15655 ab563d5679ace7ee03e86b56ee236100 251 SMART SM00420 6 58 1.9E-12 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 K08M4_RS11980 e0da2ef9af9d50ed64738605406f218f 202 PIRSF PIRSF000239 1 201 6.9E-59 T 05-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 K08M4_RS11980 e0da2ef9af9d50ed64738605406f218f 202 SUPERFAMILY SSF52833 1 194 2.62E-65 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS11980 e0da2ef9af9d50ed64738605406f218f 202 Pfam PF00578 AhpC/TSA family 4 139 2.0E-33 T 05-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 K08M4_RS11980 e0da2ef9af9d50ed64738605406f218f 202 Gene3D G3DSA:3.40.30.10 1 155 9.2E-57 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS11980 e0da2ef9af9d50ed64738605406f218f 202 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 193 1.0E-7 T 05-07-2017 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 K08M4_RS11980 e0da2ef9af9d50ed64738605406f218f 202 Gene3D G3DSA:3.30.1020.10 156 191 6.7E-12 T 05-07-2017 K08M4_RS02855 8076bdd5460084a4b6e485e86870fd43 557 Gene3D G3DSA:3.30.750.24 441 528 1.2E-9 T 05-07-2017 IPR002645 STAS domain K08M4_RS02855 8076bdd5460084a4b6e485e86870fd43 557 Pfam PF00916 Sulfate permease family 11 376 4.6E-82 T 05-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 K08M4_RS02855 8076bdd5460084a4b6e485e86870fd43 557 Pfam PF01740 STAS domain 442 534 9.8E-13 T 05-07-2017 IPR002645 STAS domain K08M4_RS02855 8076bdd5460084a4b6e485e86870fd43 557 SUPERFAMILY SSF52091 440 542 4.12E-11 T 05-07-2017 IPR002645 STAS domain K08M4_RS01585 c7fbd89da16c8f8ec01d47eeeee28104 206 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 206 35.938 T 05-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 K08M4_RS01585 c7fbd89da16c8f8ec01d47eeeee28104 206 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 206 1.2E-83 T 05-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 K08M4_RS01585 c7fbd89da16c8f8ec01d47eeeee28104 206 Gene3D G3DSA:1.10.1050.10 1 101 1.7E-40 T 05-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 K08M4_RS01585 c7fbd89da16c8f8ec01d47eeeee28104 206 ProSitePatterns PS00632 Ribosomal protein S4 signature. 94 118 - T 05-07-2017 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01585 c7fbd89da16c8f8ec01d47eeeee28104 206 SMART SM00363 96 160 5.2E-19 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS01585 c7fbd89da16c8f8ec01d47eeeee28104 206 SMART SM01390 3 95 1.9E-49 T 05-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 K08M4_RS01585 c7fbd89da16c8f8ec01d47eeeee28104 206 Gene3D G3DSA:3.10.290.10 102 190 1.6E-31 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS01585 c7fbd89da16c8f8ec01d47eeeee28104 206 SUPERFAMILY SSF55174 3 206 6.67E-71 T 05-07-2017 K08M4_RS01585 c7fbd89da16c8f8ec01d47eeeee28104 206 Pfam PF01479 S4 domain 97 143 1.2E-16 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS01585 c7fbd89da16c8f8ec01d47eeeee28104 206 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 95 7.0E-30 T 05-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 K08M4_RS16360 c33de4361d9c46624f28614d7c5acc9f 253 SUPERFAMILY SSF74653 174 250 2.49E-22 T 05-07-2017 K08M4_RS16360 c33de4361d9c46624f28614d7c5acc9f 253 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 176 252 7.4E-24 T 05-07-2017 IPR006260 TonB, C-terminal GO:0006810 K08M4_RS16360 c33de4361d9c46624f28614d7c5acc9f 253 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 175 252 5.2E-23 T 05-07-2017 IPR006260 TonB, C-terminal GO:0006810 K08M4_RS16360 c33de4361d9c46624f28614d7c5acc9f 253 Gene3D G3DSA:3.30.1150.10 175 253 1.1E-11 T 05-07-2017 K08M4_RS01485 4de4173d5d5fa5087da026dded92a1ac 92 PIRSF PIRSF002144 1 92 4.8E-32 T 05-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01485 4de4173d5d5fa5087da026dded92a1ac 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 05-07-2017 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01485 4de4173d5d5fa5087da026dded92a1ac 92 Pfam PF00203 Ribosomal protein S19 3 83 1.2E-37 T 05-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01485 4de4173d5d5fa5087da026dded92a1ac 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.888 T 05-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01485 4de4173d5d5fa5087da026dded92a1ac 92 SUPERFAMILY SSF54570 3 84 8.11E-36 T 05-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01485 4de4173d5d5fa5087da026dded92a1ac 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 7.7E-25 T 05-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01485 4de4173d5d5fa5087da026dded92a1ac 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 7.7E-25 T 05-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01485 4de4173d5d5fa5087da026dded92a1ac 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 7.7E-25 T 05-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01485 4de4173d5d5fa5087da026dded92a1ac 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 7.5E-47 T 05-07-2017 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 K08M4_RS01485 4de4173d5d5fa5087da026dded92a1ac 92 Gene3D G3DSA:3.30.860.10 1 91 1.5E-41 T 05-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS09325 7294fadcdc44243af82c8908e1172699 128 Pfam PF04024 PspC domain 3 61 2.1E-15 T 05-07-2017 IPR007168 Phage shock protein, PspC, N-terminal K08M4_RS09325 7294fadcdc44243af82c8908e1172699 128 TIGRFAM TIGR02978 phageshock_pspC: phage shock protein C 2 127 1.4E-44 T 05-07-2017 IPR014320 Phage shock protein, PspC K08M4_RS03450 b863efa86d7f7a4ee7b8d03864645bbf 179 Pfam PF11810 Domain of unknown function (DUF3332) 5 175 1.8E-40 T 05-07-2017 IPR021768 Protein of unknown function DUF3332 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 Gene3D G3DSA:3.20.20.120 128 429 7.7E-135 T 05-07-2017 IPR029065 Enolase C-terminal domain-like K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 ProSitePatterns PS00164 Enolase signature. 340 353 - T 05-07-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 Hamap MF_00318 Enolase [eno]. 2 417 44.139 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 PIRSF PIRSF001400 1 431 7.3E-191 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 SUPERFAMILY SSF54826 3 138 4.16E-55 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 Gene3D G3DSA:3.30.390.10 3 127 6.5E-54 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 SMART SM01193 4 134 1.9E-90 T 05-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 PRINTS PR00148 Enolase signature 317 328 3.9E-44 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 PRINTS PR00148 Enolase signature 37 51 3.9E-44 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 PRINTS PR00148 Enolase signature 165 178 3.9E-44 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 PRINTS PR00148 Enolase signature 107 123 3.9E-44 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 PRINTS PR00148 Enolase signature 340 354 3.9E-44 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 PRINTS PR00148 Enolase signature 369 386 3.9E-44 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 SMART SM01192 143 431 9.1E-213 T 05-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 Pfam PF00113 Enolase, C-terminal TIM barrel domain 144 430 2.5E-136 T 05-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 429 1.2E-205 T 05-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 Pfam PF03952 Enolase, N-terminal domain 4 134 4.1E-57 T 05-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS02510 073ef0f8d651ddbfc3500a67de60cd7d 432 SUPERFAMILY SSF51604 143 428 2.12E-126 T 05-07-2017 IPR029065 Enolase C-terminal domain-like K08M4_RS16130 79729a299cc8e16e9c3ed51233149232 216 Pfam PF01914 MarC family integral membrane protein 8 208 4.2E-40 T 05-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 K08M4_RS02160 53b5df62ce6188c96a98d99373142ec6 345 Gene3D G3DSA:3.40.50.300 100 339 1.8E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02160 53b5df62ce6188c96a98d99373142ec6 345 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 05-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 K08M4_RS02160 53b5df62ce6188c96a98d99373142ec6 345 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 334 8.2E-151 T 05-07-2017 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 K08M4_RS02160 53b5df62ce6188c96a98d99373142ec6 345 SUPERFAMILY SSF52540 5 336 1.41E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02160 53b5df62ce6188c96a98d99373142ec6 345 Pfam PF00437 Type II/IV secretion system protein 12 270 1.5E-45 T 05-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 K08M4_RS17220 192dda171b97d0093a0b4209785e5179 330 Gene3D G3DSA:3.40.50.1360 69 323 4.5E-71 T 05-07-2017 K08M4_RS17220 192dda171b97d0093a0b4209785e5179 330 Pfam PF04198 Putative sugar-binding domain 66 320 6.2E-75 T 05-07-2017 IPR007324 Sugar-binding domain, putative GO:0030246 K08M4_RS17220 192dda171b97d0093a0b4209785e5179 330 SUPERFAMILY SSF46689 16 80 4.66E-5 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS17220 192dda171b97d0093a0b4209785e5179 330 Gene3D G3DSA:1.10.10.10 8 60 8.9E-5 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS17220 192dda171b97d0093a0b4209785e5179 330 SUPERFAMILY SSF100950 70 320 1.76E-62 T 05-07-2017 K08M4_RS12325 823051d9c5c5310fbeccdd9e7e6345c0 510 Pfam PF01336 OB-fold nucleic acid binding domain 73 145 1.7E-6 T 05-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 K08M4_RS12325 823051d9c5c5310fbeccdd9e7e6345c0 510 SUPERFAMILY SSF55681 161 507 1.78E-115 T 05-07-2017 K08M4_RS12325 823051d9c5c5310fbeccdd9e7e6345c0 510 Pfam PF00152 tRNA synthetases class II (D, K and N) 161 506 6.8E-77 T 05-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS12325 823051d9c5c5310fbeccdd9e7e6345c0 510 Gene3D G3DSA:2.40.50.140 19 153 1.8E-34 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS12325 823051d9c5c5310fbeccdd9e7e6345c0 510 Gene3D G3DSA:3.30.930.10 156 505 2.6E-116 T 05-07-2017 K08M4_RS12325 823051d9c5c5310fbeccdd9e7e6345c0 510 SUPERFAMILY SSF50249 17 154 2.45E-33 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS12325 823051d9c5c5310fbeccdd9e7e6345c0 510 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 19 509 7.2E-201 T 05-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 K08M4_RS12325 823051d9c5c5310fbeccdd9e7e6345c0 510 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 24 509 43.395 T 05-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 K08M4_RS12325 823051d9c5c5310fbeccdd9e7e6345c0 510 PRINTS PR00982 Lysyl-tRNA synthetase signature 391 407 7.2E-39 T 05-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 K08M4_RS12325 823051d9c5c5310fbeccdd9e7e6345c0 510 PRINTS PR00982 Lysyl-tRNA synthetase signature 243 256 7.2E-39 T 05-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 K08M4_RS12325 823051d9c5c5310fbeccdd9e7e6345c0 510 PRINTS PR00982 Lysyl-tRNA synthetase signature 214 230 7.2E-39 T 05-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 K08M4_RS12325 823051d9c5c5310fbeccdd9e7e6345c0 510 PRINTS PR00982 Lysyl-tRNA synthetase signature 198 208 7.2E-39 T 05-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 K08M4_RS12325 823051d9c5c5310fbeccdd9e7e6345c0 510 PRINTS PR00982 Lysyl-tRNA synthetase signature 261 278 7.2E-39 T 05-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 K08M4_RS08010 f6eb97eb805c709e77f1775c90829267 390 Gene3D G3DSA:3.10.310.10 3 191 8.7E-91 T 05-07-2017 K08M4_RS08010 f6eb97eb805c709e77f1775c90829267 390 Gene3D G3DSA:3.10.310.10 192 369 1.6E-75 T 05-07-2017 K08M4_RS08010 f6eb97eb805c709e77f1775c90829267 390 TIGRFAM TIGR02334 prpF: probable AcnD-accessory protein PrpF 4 387 4.8E-215 T 05-07-2017 IPR012709 2-methyl-aconitate isomerase PrpF GO:0016853|GO:0019629 K08M4_RS08010 f6eb97eb805c709e77f1775c90829267 390 SUPERFAMILY SSF54506 3 181 1.18E-70 T 05-07-2017 K08M4_RS08010 f6eb97eb805c709e77f1775c90829267 390 SUPERFAMILY SSF54506 184 388 1.73E-73 T 05-07-2017 K08M4_RS08010 f6eb97eb805c709e77f1775c90829267 390 Pfam PF04303 PrpF protein 5 387 5.3E-171 T 05-07-2017 IPR007400 PrpF protein K08M4_RS11495 e5b4fe9c9de846f7207256e5fc3b319f 446 Pfam PF05896 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) 1 256 9.6E-114 T 05-07-2017 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 K08M4_RS11495 e5b4fe9c9de846f7207256e5fc3b319f 446 Hamap MF_00425 Na(+)-translocating NADH-quinone reductase subunit A [nqrA]. 1 446 46.168 T 05-07-2017 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 K08M4_RS11495 e5b4fe9c9de846f7207256e5fc3b319f 446 Pfam PF11973 NQRA C-terminal domain 261 310 8.1E-20 T 05-07-2017 IPR022615 Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain GO:0016655|GO:0055114 K08M4_RS11495 e5b4fe9c9de846f7207256e5fc3b319f 446 TIGRFAM TIGR01936 nqrA: NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit 2 446 6.0E-203 T 05-07-2017 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 K08M4_RS19050 7599f26bb31eb24f1b2f35c50bde29c0 208 PIRSF PIRSF006324 1 208 1.7E-47 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS19050 7599f26bb31eb24f1b2f35c50bde29c0 208 Pfam PF01810 LysE type translocator 18 207 4.4E-35 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS03010 dcb124ae9e07b35ef4e60480d84d03a7 340 Pfam PF08468 Methyltransferase small domain N-terminal 8 163 3.6E-56 T 05-07-2017 IPR013675 Methyltransferase small, N-terminal GO:0006364|GO:0008990 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS03010 dcb124ae9e07b35ef4e60480d84d03a7 340 Pfam PF05175 Methyltransferase small domain 172 336 5.0E-60 T 05-07-2017 IPR007848 Methyltransferase small domain GO:0008168 K08M4_RS03010 dcb124ae9e07b35ef4e60480d84d03a7 340 Hamap MF_01862 Ribosomal RNA small subunit methyltransferase C [rsmC]. 4 340 46.106 T 05-07-2017 IPR023543 rRNA small subunit methyltransferase C GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS03010 dcb124ae9e07b35ef4e60480d84d03a7 340 SUPERFAMILY SSF53335 156 318 1.79E-26 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS03010 dcb124ae9e07b35ef4e60480d84d03a7 340 Gene3D G3DSA:3.40.50.150 169 336 1.3E-22 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS03010 dcb124ae9e07b35ef4e60480d84d03a7 340 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 269 275 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 K08M4_RS06260 3ec1897bb89768a350c3ccee97052979 566 SUPERFAMILY SSF52540 303 449 4.09E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06260 3ec1897bb89768a350c3ccee97052979 566 Gene3D G3DSA:3.40.50.300 308 445 5.6E-21 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06260 3ec1897bb89768a350c3ccee97052979 566 Pfam PF01926 50S ribosome-binding GTPase 319 437 1.9E-12 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS15375 d460e3a245944ebd6e34e3c2be63f868 332 SUPERFAMILY SSF51556 5 331 2.81E-83 T 05-07-2017 IPR032466 Metal-dependent hydrolase K08M4_RS15375 d460e3a245944ebd6e34e3c2be63f868 332 Gene3D G3DSA:3.20.20.140 5 330 2.9E-99 T 05-07-2017 K08M4_RS15375 d460e3a245944ebd6e34e3c2be63f868 332 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 6 326 1.5E-90 T 05-07-2017 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 K08M4_RS15375 d460e3a245944ebd6e34e3c2be63f868 332 Hamap MF_00540 Adenosine deaminase [add]. 1 330 56.634 T 05-07-2017 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 K08M4_RS15375 d460e3a245944ebd6e34e3c2be63f868 332 Pfam PF00962 Adenosine/AMP deaminase 6 327 1.3E-75 T 05-07-2017 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 K08M4_RS09500 ef41d8cb6c3c15286625753269ba4c7a 298 Pfam PF08029 HisG, C-terminal domain 222 295 1.8E-24 T 05-07-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 K08M4_RS09500 ef41d8cb6c3c15286625753269ba4c7a 298 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 6 196 1.4E-53 T 05-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 K08M4_RS09500 ef41d8cb6c3c15286625753269ba4c7a 298 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 5 298 34.995 T 05-07-2017 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 K08M4_RS09500 ef41d8cb6c3c15286625753269ba4c7a 298 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 155 176 - T 05-07-2017 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 K08M4_RS09500 ef41d8cb6c3c15286625753269ba4c7a 298 SUPERFAMILY SSF53850 5 222 1.88E-65 T 05-07-2017 K08M4_RS09500 ef41d8cb6c3c15286625753269ba4c7a 298 SUPERFAMILY SSF54913 225 297 1.56E-21 T 05-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta K08M4_RS09500 ef41d8cb6c3c15286625753269ba4c7a 298 Pfam PF01634 ATP phosphoribosyltransferase 53 218 7.2E-45 T 05-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 K08M4_RS09500 ef41d8cb6c3c15286625753269ba4c7a 298 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 204 297 1.6E-30 T 05-07-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 K08M4_RS09500 ef41d8cb6c3c15286625753269ba4c7a 298 Gene3D G3DSA:3.30.70.120 225 297 3.2E-30 T 05-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal K08M4_RS09500 ef41d8cb6c3c15286625753269ba4c7a 298 Gene3D G3DSA:3.40.190.10 2 138 2.5E-48 T 05-07-2017 K08M4_RS09625 ef41d8cb6c3c15286625753269ba4c7a 298 Pfam PF08029 HisG, C-terminal domain 222 295 1.8E-24 T 05-07-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 K08M4_RS09625 ef41d8cb6c3c15286625753269ba4c7a 298 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 6 196 1.4E-53 T 05-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 K08M4_RS09625 ef41d8cb6c3c15286625753269ba4c7a 298 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 5 298 34.995 T 05-07-2017 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 K08M4_RS09625 ef41d8cb6c3c15286625753269ba4c7a 298 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 155 176 - T 05-07-2017 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 K08M4_RS09625 ef41d8cb6c3c15286625753269ba4c7a 298 SUPERFAMILY SSF53850 5 222 1.88E-65 T 05-07-2017 K08M4_RS09625 ef41d8cb6c3c15286625753269ba4c7a 298 SUPERFAMILY SSF54913 225 297 1.56E-21 T 05-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta K08M4_RS09625 ef41d8cb6c3c15286625753269ba4c7a 298 Pfam PF01634 ATP phosphoribosyltransferase 53 218 7.2E-45 T 05-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 K08M4_RS09625 ef41d8cb6c3c15286625753269ba4c7a 298 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 204 297 1.6E-30 T 05-07-2017 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 K08M4_RS09625 ef41d8cb6c3c15286625753269ba4c7a 298 Gene3D G3DSA:3.30.70.120 225 297 3.2E-30 T 05-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal K08M4_RS09625 ef41d8cb6c3c15286625753269ba4c7a 298 Gene3D G3DSA:3.40.190.10 2 138 2.5E-48 T 05-07-2017 K08M4_RS14190 cf4a1f3a24b8816c810bd55d3ac6d7c0 275 SUPERFAMILY SSF56655 6 271 1.83E-77 T 05-07-2017 K08M4_RS14190 cf4a1f3a24b8816c810bd55d3ac6d7c0 275 Gene3D G3DSA:3.40.190.80 164 262 3.2E-35 T 05-07-2017 K08M4_RS14190 cf4a1f3a24b8816c810bd55d3ac6d7c0 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 43 63 2.0E-14 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 K08M4_RS14190 cf4a1f3a24b8816c810bd55d3ac6d7c0 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 65 81 2.0E-14 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 K08M4_RS14190 cf4a1f3a24b8816c810bd55d3ac6d7c0 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 89 105 2.0E-14 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 K08M4_RS14190 cf4a1f3a24b8816c810bd55d3ac6d7c0 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 217 241 2.0E-14 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 K08M4_RS14190 cf4a1f3a24b8816c810bd55d3ac6d7c0 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 185 206 2.0E-14 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 K08M4_RS14190 cf4a1f3a24b8816c810bd55d3ac6d7c0 275 Pfam PF00459 Inositol monophosphatase family 7 253 1.6E-51 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 K08M4_RS14190 cf4a1f3a24b8816c810bd55d3ac6d7c0 275 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 10 260 2.4E-105 T 05-07-2017 IPR006240 3(2),5 -bisphosphate nucleotidase, bacterial GO:0000287|GO:0016020 KEGG: 00920+3.1.3.7 K08M4_RS14190 cf4a1f3a24b8816c810bd55d3ac6d7c0 275 Gene3D G3DSA:3.30.540.10 6 163 5.6E-46 T 05-07-2017 K08M4_RS14900 79d421c34c745731bdfaec76c1bcc794 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 297 330 2.2E-6 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS14900 79d421c34c745731bdfaec76c1bcc794 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 265 296 2.8E-5 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS14900 79d421c34c745731bdfaec76c1bcc794 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 392 426 1.0E-8 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS14900 79d421c34c745731bdfaec76c1bcc794 453 Pfam PF12804 MobA-like NTP transferase domain 5 124 1.0E-22 T 05-07-2017 IPR025877 MobA-like NTP transferase K08M4_RS14900 79d421c34c745731bdfaec76c1bcc794 453 SUPERFAMILY SSF51161 252 435 1.09E-51 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS14900 79d421c34c745731bdfaec76c1bcc794 453 Gene3D G3DSA:2.160.10.10 243 321 2.0E-20 T 05-07-2017 K08M4_RS14900 79d421c34c745731bdfaec76c1bcc794 453 Gene3D G3DSA:3.90.550.10 1 242 1.2E-68 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS14900 79d421c34c745731bdfaec76c1bcc794 453 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 452 2.9E-204 T 05-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 K08M4_RS14900 79d421c34c745731bdfaec76c1bcc794 453 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 449 42.448 T 05-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 K08M4_RS14900 79d421c34c745731bdfaec76c1bcc794 453 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 400 428 - T 05-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 K08M4_RS14900 79d421c34c745731bdfaec76c1bcc794 453 SUPERFAMILY SSF53448 1 249 1.91E-64 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS14900 79d421c34c745731bdfaec76c1bcc794 453 Gene3D G3DSA:2.160.10.10 322 451 1.8E-34 T 05-07-2017 K08M4_RS19540 b08045c6cdffec84989c2517e6459289 334 SUPERFAMILY SSF53822 61 318 5.89E-37 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS19540 b08045c6cdffec84989c2517e6459289 334 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 63 254 7.1E-13 T 05-07-2017 IPR001761 Periplasmic binding protein/LacI sugar binding domain K08M4_RS19540 b08045c6cdffec84989c2517e6459289 334 Gene3D G3DSA:3.40.50.2300 61 166 5.4E-26 T 05-07-2017 K08M4_RS19540 b08045c6cdffec84989c2517e6459289 334 SUPERFAMILY SSF47413 1 58 5.91E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS19540 b08045c6cdffec84989c2517e6459289 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 2 50 6.9E-18 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS19540 b08045c6cdffec84989c2517e6459289 334 Gene3D G3DSA:1.10.260.40 1 60 3.0E-24 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS19540 b08045c6cdffec84989c2517e6459289 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 3 21 - T 05-07-2017 K08M4_RS19540 b08045c6cdffec84989c2517e6459289 334 TIGRFAM TIGR02417 fruct_sucro_rep: D-fructose-responsive transcription factor 2 333 2.2E-136 T 05-07-2017 IPR012781 D-fructose-responsive transcription factor GO:0003677|GO:0006355|GO:0009750 K08M4_RS19540 b08045c6cdffec84989c2517e6459289 334 SMART SM00354 1 73 2.3E-27 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS19540 b08045c6cdffec84989c2517e6459289 334 Gene3D G3DSA:3.40.50.2300 167 334 1.5E-26 T 05-07-2017 K08M4_RS16075 ed34b68c26ac747a874e875c65b21e63 440 Pfam PF01609 Transposase DDE domain 132 355 2.9E-21 T 05-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 K08M4_RS16075 ed34b68c26ac747a874e875c65b21e63 440 SUPERFAMILY SSF53098 107 360 5.39E-23 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS16075 ed34b68c26ac747a874e875c65b21e63 440 Pfam PF13006 Insertion element 4 transposase N-terminal 22 112 3.0E-21 T 05-07-2017 IPR024473 Transposase, IS4, N-terminal K08M4_RS11690 ed34b68c26ac747a874e875c65b21e63 440 Pfam PF01609 Transposase DDE domain 132 355 2.9E-21 T 05-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 K08M4_RS11690 ed34b68c26ac747a874e875c65b21e63 440 SUPERFAMILY SSF53098 107 360 5.39E-23 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS11690 ed34b68c26ac747a874e875c65b21e63 440 Pfam PF13006 Insertion element 4 transposase N-terminal 22 112 3.0E-21 T 05-07-2017 IPR024473 Transposase, IS4, N-terminal K08M4_RS17180 ed34b68c26ac747a874e875c65b21e63 440 Pfam PF01609 Transposase DDE domain 132 355 2.9E-21 T 05-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 K08M4_RS17180 ed34b68c26ac747a874e875c65b21e63 440 SUPERFAMILY SSF53098 107 360 5.39E-23 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS17180 ed34b68c26ac747a874e875c65b21e63 440 Pfam PF13006 Insertion element 4 transposase N-terminal 22 112 3.0E-21 T 05-07-2017 IPR024473 Transposase, IS4, N-terminal K08M4_RS09270 ed34b68c26ac747a874e875c65b21e63 440 Pfam PF01609 Transposase DDE domain 132 355 2.9E-21 T 05-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 K08M4_RS09270 ed34b68c26ac747a874e875c65b21e63 440 SUPERFAMILY SSF53098 107 360 5.39E-23 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS09270 ed34b68c26ac747a874e875c65b21e63 440 Pfam PF13006 Insertion element 4 transposase N-terminal 22 112 3.0E-21 T 05-07-2017 IPR024473 Transposase, IS4, N-terminal K08M4_RS04945 ed34b68c26ac747a874e875c65b21e63 440 Pfam PF01609 Transposase DDE domain 132 355 2.9E-21 T 05-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 K08M4_RS04945 ed34b68c26ac747a874e875c65b21e63 440 SUPERFAMILY SSF53098 107 360 5.39E-23 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS04945 ed34b68c26ac747a874e875c65b21e63 440 Pfam PF13006 Insertion element 4 transposase N-terminal 22 112 3.0E-21 T 05-07-2017 IPR024473 Transposase, IS4, N-terminal K08M4_RS08720 3eab7cea6b65e8e5e74eba0c76fbfe22 457 Pfam PF01554 MatE 251 414 2.7E-19 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS08720 3eab7cea6b65e8e5e74eba0c76fbfe22 457 Pfam PF01554 MatE 24 184 2.6E-26 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS08720 3eab7cea6b65e8e5e74eba0c76fbfe22 457 PIRSF PIRSF006603 5 457 4.9E-62 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS08720 3eab7cea6b65e8e5e74eba0c76fbfe22 457 TIGRFAM TIGR00797 matE: MATE efflux family protein 24 420 5.5E-60 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS14815 6e7ff3f8e9ef88b9ffb6143df79cd8e7 184 Pfam PF11355 Protein of unknown function (DUF3157) 11 183 5.2E-42 T 05-07-2017 IPR021501 Protein of unknown function DUF3157 K08M4_RS06440 b66a875c29bb1298496ce22efde51d53 682 Pfam PF00072 Response regulator receiver domain 566 678 5.4E-26 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS06440 b66a875c29bb1298496ce22efde51d53 682 SMART SM00448 564 678 8.3E-33 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS06440 b66a875c29bb1298496ce22efde51d53 682 Gene3D G3DSA:3.40.50.2300 559 681 1.4E-36 T 05-07-2017 K08M4_RS06440 b66a875c29bb1298496ce22efde51d53 682 SUPERFAMILY SSF55874 251 414 8.51E-30 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS06440 b66a875c29bb1298496ce22efde51d53 682 Gene3D G3DSA:3.30.565.10 252 415 5.3E-29 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS06440 b66a875c29bb1298496ce22efde51d53 682 SMART SM00387 306 414 6.3E-21 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS06440 b66a875c29bb1298496ce22efde51d53 682 SUPERFAMILY SSF47384 170 230 1.16E-5 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS06440 b66a875c29bb1298496ce22efde51d53 682 Pfam PF00512 His Kinase A (phospho-acceptor) domain 184 257 1.0E-6 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS06440 b66a875c29bb1298496ce22efde51d53 682 Gene3D G3DSA:1.10.287.130 176 251 6.0E-5 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS06440 b66a875c29bb1298496ce22efde51d53 682 SUPERFAMILY SSF52172 562 682 1.99E-35 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS06440 b66a875c29bb1298496ce22efde51d53 682 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 1.7E-9 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS06440 b66a875c29bb1298496ce22efde51d53 682 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 372 1.7E-9 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS06440 b66a875c29bb1298496ce22efde51d53 682 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 392 1.7E-9 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS06440 b66a875c29bb1298496ce22efde51d53 682 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 411 1.7E-9 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS06440 b66a875c29bb1298496ce22efde51d53 682 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 309 411 8.5E-18 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS03910 28b3f3db242dffe8e2a83acbb8a4ed60 399 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 248 347 7.3E-27 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal K08M4_RS03910 28b3f3db242dffe8e2a83acbb8a4ed60 399 Gene3D G3DSA:3.40.47.10 2 231 1.9E-33 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS03910 28b3f3db242dffe8e2a83acbb8a4ed60 399 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 149 165 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site K08M4_RS03910 28b3f3db242dffe8e2a83acbb8a4ed60 399 SUPERFAMILY SSF53901 204 395 2.78E-43 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS03910 28b3f3db242dffe8e2a83acbb8a4ed60 399 Gene3D G3DSA:3.40.47.10 253 395 2.8E-47 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS03910 28b3f3db242dffe8e2a83acbb8a4ed60 399 SUPERFAMILY SSF53901 2 229 9.6E-38 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS03910 28b3f3db242dffe8e2a83acbb8a4ed60 399 SMART SM00825 Beta-ketoacyl synthase 36 350 6.7E-8 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain K08M4_RS03910 28b3f3db242dffe8e2a83acbb8a4ed60 399 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 68 230 6.8E-22 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal K08M4_RS12755 6be3a0c51d1547b97f2dd9be6b6c54b5 505 SMART SM00880 229 497 2.0E-24 T 05-07-2017 IPR007899 CHAD domain K08M4_RS12755 6be3a0c51d1547b97f2dd9be6b6c54b5 505 SMART SM01118 2 203 2.9E-42 T 05-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 K08M4_RS12755 6be3a0c51d1547b97f2dd9be6b6c54b5 505 Pfam PF05235 CHAD domain 230 384 6.1E-7 T 05-07-2017 IPR007899 CHAD domain K08M4_RS12755 6be3a0c51d1547b97f2dd9be6b6c54b5 505 SUPERFAMILY SSF55154 1 216 4.25E-52 T 05-07-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 K08M4_RS12755 6be3a0c51d1547b97f2dd9be6b6c54b5 505 Gene3D G3DSA:2.40.320.10 1 210 3.3E-39 T 05-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 K08M4_RS12755 6be3a0c51d1547b97f2dd9be6b6c54b5 505 Pfam PF01928 CYTH domain 3 197 5.2E-34 T 05-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 K08M4_RS10870 137a5d475c4cfd026371b5d511de5f4b 385 Pfam PF13609 Gram-negative porin 13 312 8.5E-29 T 05-07-2017 K08M4_RS10870 137a5d475c4cfd026371b5d511de5f4b 385 Gene3D G3DSA:2.40.160.10 37 385 4.8E-39 T 05-07-2017 IPR023614 Porin domain K08M4_RS10870 137a5d475c4cfd026371b5d511de5f4b 385 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 167 178 6.3E-6 T 05-07-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 K08M4_RS10870 137a5d475c4cfd026371b5d511de5f4b 385 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 377 385 6.3E-6 T 05-07-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 K08M4_RS10870 137a5d475c4cfd026371b5d511de5f4b 385 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 110 120 6.3E-6 T 05-07-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 K08M4_RS10870 137a5d475c4cfd026371b5d511de5f4b 385 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 69 80 6.3E-6 T 05-07-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 K08M4_RS10870 137a5d475c4cfd026371b5d511de5f4b 385 SUPERFAMILY SSF56935 252 385 1.8E-38 T 05-07-2017 K08M4_RS10870 137a5d475c4cfd026371b5d511de5f4b 385 SUPERFAMILY SSF56935 36 222 1.8E-38 T 05-07-2017 K08M4_RS10870 137a5d475c4cfd026371b5d511de5f4b 385 PRINTS PR00184 Neisseria sp. porin signature 108 127 1.4E-8 T 05-07-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 K08M4_RS10870 137a5d475c4cfd026371b5d511de5f4b 385 PRINTS PR00184 Neisseria sp. porin signature 166 183 1.4E-8 T 05-07-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 K08M4_RS10870 137a5d475c4cfd026371b5d511de5f4b 385 PRINTS PR00184 Neisseria sp. porin signature 71 96 1.4E-8 T 05-07-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 K08M4_RS18810 302f0efa7c1f76d3fac6053704a5c298 579 SUPERFAMILY SSF56300 5 365 1.94E-74 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS18810 302f0efa7c1f76d3fac6053704a5c298 579 Gene3D G3DSA:3.60.21.10 3 364 4.4E-79 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS18810 302f0efa7c1f76d3fac6053704a5c298 579 SUPERFAMILY SSF55816 366 563 3.01E-37 T 05-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS18810 302f0efa7c1f76d3fac6053704a5c298 579 Pfam PF02872 5'-nucleotidase, C-terminal domain 368 537 7.7E-20 T 05-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS18810 302f0efa7c1f76d3fac6053704a5c298 579 Gene3D G3DSA:3.90.780.10 368 563 2.6E-27 T 05-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS18810 302f0efa7c1f76d3fac6053704a5c298 579 PRINTS PR01607 Apyrase family signature 232 255 6.1E-16 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS18810 302f0efa7c1f76d3fac6053704a5c298 579 PRINTS PR01607 Apyrase family signature 272 292 6.1E-16 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS18810 302f0efa7c1f76d3fac6053704a5c298 579 PRINTS PR01607 Apyrase family signature 512 531 6.1E-16 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS18810 302f0efa7c1f76d3fac6053704a5c298 579 PRINTS PR01607 Apyrase family signature 213 230 6.1E-16 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS18810 302f0efa7c1f76d3fac6053704a5c298 579 PRINTS PR01607 Apyrase family signature 8 26 6.1E-16 T 05-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 K08M4_RS18810 302f0efa7c1f76d3fac6053704a5c298 579 Pfam PF00149 Calcineurin-like phosphoesterase 12 249 2.4E-7 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 K08M4_RS03240 3ca52f886fc0b137249b4f2cb2cd0f00 406 SUPERFAMILY SSF143856 118 234 4.97E-46 T 05-07-2017 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 K08M4_RS03240 3ca52f886fc0b137249b4f2cb2cd0f00 406 Gene3D G3DSA:3.30.70.1250 115 234 8.0E-49 T 05-07-2017 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 K08M4_RS03240 3ca52f886fc0b137249b4f2cb2cd0f00 406 Hamap MF_00740 Phosphopentomutase [deoB]. 1 406 52.775 T 05-07-2017 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 K08M4_RS03240 3ca52f886fc0b137249b4f2cb2cd0f00 406 TIGRFAM TIGR01696 deoB: phosphopentomutase 3 404 2.6E-171 T 05-07-2017 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 K08M4_RS03240 3ca52f886fc0b137249b4f2cb2cd0f00 406 Gene3D G3DSA:3.40.720.10 1 114 6.3E-71 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 K08M4_RS03240 3ca52f886fc0b137249b4f2cb2cd0f00 406 Gene3D G3DSA:3.40.720.10 239 406 6.3E-71 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 K08M4_RS03240 3ca52f886fc0b137249b4f2cb2cd0f00 406 Pfam PF01676 Metalloenzyme superfamily 2 397 2.5E-40 T 05-07-2017 IPR006124 Metalloenzyme GO:0003824|GO:0046872 K08M4_RS03240 3ca52f886fc0b137249b4f2cb2cd0f00 406 SUPERFAMILY SSF53649 1 115 1.57E-69 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 K08M4_RS03240 3ca52f886fc0b137249b4f2cb2cd0f00 406 SUPERFAMILY SSF53649 236 406 1.57E-69 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 K08M4_RS03240 3ca52f886fc0b137249b4f2cb2cd0f00 406 PIRSF PIRSF001491 1 406 1.6E-155 T 05-07-2017 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 K08M4_RS02475 19e8329e4cb5fb6a176050b2317f85e7 126 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 3 126 2.6E-42 T 05-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 K08M4_RS02475 19e8329e4cb5fb6a176050b2317f85e7 126 Gene3D G3DSA:3.90.470.20 1 125 1.3E-41 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 K08M4_RS02475 19e8329e4cb5fb6a176050b2317f85e7 126 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 122 1.8E-23 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 K08M4_RS02475 19e8329e4cb5fb6a176050b2317f85e7 126 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 87 2.0E-33 T 05-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 K08M4_RS02475 19e8329e4cb5fb6a176050b2317f85e7 126 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 126 1.9E-33 T 05-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 K08M4_RS02475 19e8329e4cb5fb6a176050b2317f85e7 126 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 126 26.68 T 05-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 K08M4_RS02475 19e8329e4cb5fb6a176050b2317f85e7 126 SUPERFAMILY SSF56214 3 125 1.57E-31 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 K08M4_RS06665 8634f4ddb87c33ac84ab0ce923ad2434 165 Pfam PF01863 Protein of unknown function DUF45 94 150 1.0E-10 T 05-07-2017 IPR002725 Protein of unknown function DUF45 K08M4_RS21205 53f7831dd69419c86052c12ea1d99f7d 542 SUPERFAMILY SSF52540 6 256 6.63E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21205 53f7831dd69419c86052c12ea1d99f7d 542 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 263 7.2E-6 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS21205 53f7831dd69419c86052c12ea1d99f7d 542 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 506 538 0.0041 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS21205 53f7831dd69419c86052c12ea1d99f7d 542 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS21205 53f7831dd69419c86052c12ea1d99f7d 542 ProSitePatterns PS00211 ABC transporters family signature. 427 441 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS21205 53f7831dd69419c86052c12ea1d99f7d 542 Gene3D G3DSA:3.40.50.300 297 528 2.2E-77 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21205 53f7831dd69419c86052c12ea1d99f7d 542 Gene3D G3DSA:3.40.50.300 6 259 2.0E-71 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21205 53f7831dd69419c86052c12ea1d99f7d 542 SUPERFAMILY SSF52540 294 526 2.03E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21205 53f7831dd69419c86052c12ea1d99f7d 542 Pfam PF00005 ABC transporter 27 185 2.6E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS21205 53f7831dd69419c86052c12ea1d99f7d 542 Pfam PF00005 ABC transporter 304 455 4.4E-33 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS21205 53f7831dd69419c86052c12ea1d99f7d 542 SMART SM00382 312 504 2.4E-19 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS21205 53f7831dd69419c86052c12ea1d99f7d 542 SMART SM00382 35 235 1.0E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS08220 c49f2a41c9f467c58e32621c60936e22 212 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 142 152 - T 05-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 K08M4_RS08220 c49f2a41c9f467c58e32621c60936e22 212 Gene3D G3DSA:1.10.286.10 2 82 1.6E-28 T 05-07-2017 K08M4_RS08220 c49f2a41c9f467c58e32621c60936e22 212 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 36 212 2.1E-75 T 05-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 K08M4_RS08220 c49f2a41c9f467c58e32621c60936e22 212 Gene3D G3DSA:3.30.1130.10 88 212 1.5E-48 T 05-07-2017 K08M4_RS08220 c49f2a41c9f467c58e32621c60936e22 212 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 32 212 30.625 T 05-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 K08M4_RS08220 c49f2a41c9f467c58e32621c60936e22 212 Pfam PF01227 GTP cyclohydrolase I 40 211 2.0E-60 T 05-07-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 K08M4_RS08220 c49f2a41c9f467c58e32621c60936e22 212 SUPERFAMILY SSF55620 7 211 1.56E-69 T 05-07-2017 K08M4_RS04625 b27d4d9653d0509df5bb0614337b4fb7 229 Gene3D G3DSA:1.20.1080.10 2 227 4.1E-68 T 05-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 K08M4_RS04625 b27d4d9653d0509df5bb0614337b4fb7 229 Pfam PF00230 Major intrinsic protein 3 222 1.9E-48 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS04625 b27d4d9653d0509df5bb0614337b4fb7 229 TIGRFAM TIGR00861 MIP: MIP family channel proteins 6 222 1.2E-59 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS04625 b27d4d9653d0509df5bb0614337b4fb7 229 SUPERFAMILY SSF81338 2 226 2.22E-68 T 05-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 K08M4_RS04625 b27d4d9653d0509df5bb0614337b4fb7 229 Hamap MF_01146 Aquaporin Z [aqpZ]. 1 229 35.18 T 05-07-2017 IPR023743 Aquaporin Z GO:0006833|GO:0015250|GO:0016021|GO:0055085 K08M4_RS04625 b27d4d9653d0509df5bb0614337b4fb7 229 ProSitePatterns PS00221 MIP family signature. 60 68 - T 05-07-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS04625 b27d4d9653d0509df5bb0614337b4fb7 229 PRINTS PR00783 Major intrinsic protein family signature 136 154 7.0E-53 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS04625 b27d4d9653d0509df5bb0614337b4fb7 229 PRINTS PR00783 Major intrinsic protein family signature 166 188 7.0E-53 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS04625 b27d4d9653d0509df5bb0614337b4fb7 229 PRINTS PR00783 Major intrinsic protein family signature 79 98 7.0E-53 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS04625 b27d4d9653d0509df5bb0614337b4fb7 229 PRINTS PR00783 Major intrinsic protein family signature 2 21 7.0E-53 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS04625 b27d4d9653d0509df5bb0614337b4fb7 229 PRINTS PR00783 Major intrinsic protein family signature 42 66 7.0E-53 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS04625 b27d4d9653d0509df5bb0614337b4fb7 229 PRINTS PR00783 Major intrinsic protein family signature 205 225 7.0E-53 T 05-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 Gene3D G3DSA:3.30.70.1430 42 140 6.1E-24 T 05-07-2017 K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 Gene3D G3DSA:1.20.1640.10 291 500 2.4E-42 T 05-07-2017 K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 Gene3D G3DSA:1.10.3850.10 800 1013 1.3E-57 T 05-07-2017 K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 Gene3D G3DSA:3.30.2090.10 712 788 3.7E-5 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 Gene3D G3DSA:3.30.2090.10 186 266 2.3E-6 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 SUPERFAMILY SSF82714 185 266 5.1E-6 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 Pfam PF00873 AcrB/AcrD/AcrF family 4 1011 1.1E-168 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 SUPERFAMILY SSF82866 792 1014 1.31E-46 T 05-07-2017 K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 SUPERFAMILY SSF82693 136 182 3.82E-18 T 05-07-2017 K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 SUPERFAMILY SSF82693 270 325 3.82E-18 T 05-07-2017 K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 SUPERFAMILY SSF82714 712 788 4.32E-8 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 SUPERFAMILY SSF82866 293 491 8.5E-35 T 05-07-2017 K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 2.1E-28 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 2.1E-28 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 2.1E-28 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.1E-28 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.1E-28 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 PRINTS PR00702 Acriflavin resistance protein family signature 332 355 2.1E-28 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS16125 f2869098104ec661bb50dba46385d534 1017 SUPERFAMILY SSF82693 41 135 1.92E-19 T 05-07-2017 K08M4_RS13855 54bfd8b032739392207b9df7f7fe3979 404 Pfam PF00534 Glycosyl transferases group 1 217 309 2.5E-12 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 K08M4_RS13855 54bfd8b032739392207b9df7f7fe3979 404 SUPERFAMILY SSF53756 3 326 2.89E-30 T 05-07-2017 K08M4_RS13855 54bfd8b032739392207b9df7f7fe3979 404 Gene3D G3DSA:3.40.50.2000 215 309 7.8E-5 T 05-07-2017 K08M4_RS01065 eb5f8fa3d99ebfe87b3acd5fb99b6f07 229 SUPERFAMILY SSF52172 1 125 8.4E-39 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS01065 eb5f8fa3d99ebfe87b3acd5fb99b6f07 229 SMART SM00448 2 111 6.3E-43 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS01065 eb5f8fa3d99ebfe87b3acd5fb99b6f07 229 Pfam PF00072 Response regulator receiver domain 4 112 2.3E-27 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS01065 eb5f8fa3d99ebfe87b3acd5fb99b6f07 229 Gene3D G3DSA:1.10.10.10 126 228 1.2E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS01065 eb5f8fa3d99ebfe87b3acd5fb99b6f07 229 SUPERFAMILY SSF46894 125 226 3.68E-24 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS01065 eb5f8fa3d99ebfe87b3acd5fb99b6f07 229 Gene3D G3DSA:3.40.50.2300 2 120 1.0E-37 T 05-07-2017 K08M4_RS01065 eb5f8fa3d99ebfe87b3acd5fb99b6f07 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 225 2.3E-20 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS01065 eb5f8fa3d99ebfe87b3acd5fb99b6f07 229 SMART SM00862 149 225 5.0E-22 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS14760 6e06117c0c98a8b45f8986d381d1f968 161 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 156 32.183 T 05-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 K08M4_RS14760 6e06117c0c98a8b45f8986d381d1f968 161 Gene3D G3DSA:3.40.50.7700 1 158 2.8E-73 T 05-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 K08M4_RS14760 6e06117c0c98a8b45f8986d381d1f968 161 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 157 2.1E-66 T 05-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 K08M4_RS14760 6e06117c0c98a8b45f8986d381d1f968 161 SMART SM01001 1 152 3.0E-101 T 05-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 K08M4_RS14760 6e06117c0c98a8b45f8986d381d1f968 161 PIRSF PIRSF001338 1 160 1.4E-67 T 05-07-2017 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 K08M4_RS14760 6e06117c0c98a8b45f8986d381d1f968 161 SUPERFAMILY SSF52255 2 158 7.72E-66 T 05-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 K08M4_RS14760 6e06117c0c98a8b45f8986d381d1f968 161 Pfam PF00731 AIR carboxylase 3 150 8.1E-64 T 05-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 K08M4_RS06905 581897295dd917fe7165599ed3d46f44 676 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 167 9.5E-27 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS06905 581897295dd917fe7165599ed3d46f44 676 SUPERFAMILY SSF56935 35 676 2.04E-123 T 05-07-2017 K08M4_RS06905 581897295dd917fe7165599ed3d46f44 676 Pfam PF00593 TonB dependent receptor 416 674 1.7E-34 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS06905 581897295dd917fe7165599ed3d46f44 676 Gene3D G3DSA:2.170.130.10 35 171 2.1E-41 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS06905 581897295dd917fe7165599ed3d46f44 676 Gene3D G3DSA:2.40.170.20 172 676 6.7E-96 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS14055 7295ed891a3712605fcef06d02c28761 70 Gene3D G3DSA:2.40.50.140 5 68 1.2E-30 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS14055 7295ed891a3712605fcef06d02c28761 70 SUPERFAMILY SSF50249 4 69 3.0E-25 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS14055 7295ed891a3712605fcef06d02c28761 70 SMART SM00357 6 70 1.5E-30 T 05-07-2017 IPR011129 Cold shock protein GO:0003676 K08M4_RS14055 7295ed891a3712605fcef06d02c28761 70 PRINTS PR00050 Cold shock protein signature 28 37 1.9E-17 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS14055 7295ed891a3712605fcef06d02c28761 70 PRINTS PR00050 Cold shock protein signature 43 61 1.9E-17 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS14055 7295ed891a3712605fcef06d02c28761 70 PRINTS PR00050 Cold shock protein signature 7 22 1.9E-17 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS14055 7295ed891a3712605fcef06d02c28761 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 05-07-2017 IPR019844 Cold-shock conserved site K08M4_RS14055 7295ed891a3712605fcef06d02c28761 70 Pfam PF00313 'Cold-shock' DNA-binding domain 6 69 2.3E-29 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS14055 7295ed891a3712605fcef06d02c28761 70 PIRSF PIRSF002599 1 70 1.2E-24 T 05-07-2017 IPR012156 Cold shock, CspA GO:0003676 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 173 220 3.1E-13 T 05-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 Gene3D G3DSA:3.30.930.10 243 531 2.5E-123 T 05-07-2017 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 465 493 9.2E-54 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 363 386 9.2E-54 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 535 547 9.2E-54 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 330 358 9.2E-54 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 508 521 9.2E-54 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 Pfam PF03129 Anticodon binding domain 542 631 2.6E-22 T 05-07-2017 IPR004154 Anticodon-binding K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 Pfam PF02824 TGS domain 4 61 9.0E-11 T 05-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 SMART SM00863 171 220 1.5E-18 T 05-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 Gene3D G3DSA:3.10.20.30 1 64 1.0E-22 T 05-07-2017 IPR012675 Beta-grasp domain K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 Gene3D G3DSA:3.30.54.20 132 188 2.7E-21 T 05-07-2017 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 SUPERFAMILY SSF52954 530 637 2.11E-31 T 05-07-2017 IPR004154 Anticodon-binding K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 Gene3D G3DSA:3.30.980.10 189 224 1.1E-41 T 05-07-2017 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 Gene3D G3DSA:3.30.980.10 67 130 1.1E-41 T 05-07-2017 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 SUPERFAMILY SSF81271 3 61 8.17E-16 T 05-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 SUPERFAMILY SSF55681 244 527 4.58E-99 T 05-07-2017 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 SUPERFAMILY SSF55186 65 242 1.83E-63 T 05-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 73 632 1.7E-241 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 67 635 34.146 T 05-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 319 530 2.5E-49 T 05-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS06105 198f1a9c6c033bfc85d097e7508b9aef 642 Gene3D G3DSA:3.40.50.800 533 639 8.0E-36 T 05-07-2017 IPR004154 Anticodon-binding K08M4_RS05670 ac8451727e606ebe540eff9817490a11 432 SUPERFAMILY SSF47384 206 288 3.53E-14 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS05670 ac8451727e606ebe540eff9817490a11 432 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 340 413 1.8E-5 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS05670 ac8451727e606ebe540eff9817490a11 432 Gene3D G3DSA:1.10.287.130 216 283 1.4E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS05670 ac8451727e606ebe540eff9817490a11 432 Gene3D G3DSA:3.30.565.10 302 422 1.6E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS05670 ac8451727e606ebe540eff9817490a11 432 SUPERFAMILY SSF55874 279 418 1.1E-16 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS05670 ac8451727e606ebe540eff9817490a11 432 Pfam PF00512 His Kinase A (phospho-acceptor) domain 226 286 1.3E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS05670 ac8451727e606ebe540eff9817490a11 432 SMART SM00387 332 422 1.4E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS05670 ac8451727e606ebe540eff9817490a11 432 SMART SM00388 223 288 1.3E-12 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS09045 4c6074e38d53ec22a448ceea5364c522 146 Pfam PF03918 Cytochrome C biogenesis protein 38 145 4.2E-41 T 05-07-2017 IPR005616 CcmH/CycL/Ccl2/NrfF family K08M4_RS18590 e732b8bd92a2c4f9c9af7547ccdb0385 337 PRINTS PR01713 Nucleotide sugar epimerase signature 230 245 7.6E-6 T 05-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 K08M4_RS18590 e732b8bd92a2c4f9c9af7547ccdb0385 337 PRINTS PR01713 Nucleotide sugar epimerase signature 255 270 7.6E-6 T 05-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 K08M4_RS18590 e732b8bd92a2c4f9c9af7547ccdb0385 337 PRINTS PR01713 Nucleotide sugar epimerase signature 294 311 7.6E-6 T 05-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 K08M4_RS18590 e732b8bd92a2c4f9c9af7547ccdb0385 337 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 333 5.7E-139 T 05-07-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 K08M4_RS18590 e732b8bd92a2c4f9c9af7547ccdb0385 337 Gene3D G3DSA:3.90.25.10 263 335 5.1E-52 T 05-07-2017 K08M4_RS18590 e732b8bd92a2c4f9c9af7547ccdb0385 337 Gene3D G3DSA:3.90.25.10 179 231 5.1E-52 T 05-07-2017 K08M4_RS18590 e732b8bd92a2c4f9c9af7547ccdb0385 337 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 324 2.5E-61 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS18590 e732b8bd92a2c4f9c9af7547ccdb0385 337 SUPERFAMILY SSF51735 1 333 5.43E-94 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS18590 e732b8bd92a2c4f9c9af7547ccdb0385 337 Gene3D G3DSA:3.40.50.720 1 178 1.1E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS01280 143b0f8ada5651de1832125adacaa477 172 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 05-07-2017 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 K08M4_RS01280 143b0f8ada5651de1832125adacaa477 172 PRINTS PR01100 Shikimate kinase family signature 77 86 2.7E-29 T 05-07-2017 K08M4_RS01280 143b0f8ada5651de1832125adacaa477 172 PRINTS PR01100 Shikimate kinase family signature 59 67 2.7E-29 T 05-07-2017 K08M4_RS01280 143b0f8ada5651de1832125adacaa477 172 PRINTS PR01100 Shikimate kinase family signature 7 22 2.7E-29 T 05-07-2017 K08M4_RS01280 143b0f8ada5651de1832125adacaa477 172 PRINTS PR01100 Shikimate kinase family signature 31 44 2.7E-29 T 05-07-2017 K08M4_RS01280 143b0f8ada5651de1832125adacaa477 172 PRINTS PR01100 Shikimate kinase family signature 98 115 2.7E-29 T 05-07-2017 K08M4_RS01280 143b0f8ada5651de1832125adacaa477 172 SUPERFAMILY SSF52540 4 169 3.55E-31 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01280 143b0f8ada5651de1832125adacaa477 172 Gene3D G3DSA:3.40.50.300 2 171 5.3E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01280 143b0f8ada5651de1832125adacaa477 172 Pfam PF01202 Shikimate kinase 13 169 4.7E-56 T 05-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 K08M4_RS01280 143b0f8ada5651de1832125adacaa477 172 Hamap MF_00109 Shikimate kinase [aroK]. 4 170 29.151 T 05-07-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 K08M4_RS15240 749457b10a986b3e6a2d1abd910cbd97 177 SUPERFAMILY SSF55729 23 153 3.32E-18 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS15240 749457b10a986b3e6a2d1abd910cbd97 177 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 23 176 5.1E-60 T 05-07-2017 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 K08M4_RS15240 749457b10a986b3e6a2d1abd910cbd97 177 Gene3D G3DSA:3.40.630.30 21 175 2.3E-64 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS15240 749457b10a986b3e6a2d1abd910cbd97 177 Pfam PF00583 Acetyltransferase (GNAT) family 67 143 1.4E-10 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS14235 c1d0a743dba1c85b89402d38f99768c4 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 67 79 1.1E-36 T 05-07-2017 IPR003004 GspF/PilC family K08M4_RS14235 c1d0a743dba1c85b89402d38f99768c4 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 166 194 1.1E-36 T 05-07-2017 IPR003004 GspF/PilC family K08M4_RS14235 c1d0a743dba1c85b89402d38f99768c4 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 369 383 1.1E-36 T 05-07-2017 IPR003004 GspF/PilC family K08M4_RS14235 c1d0a743dba1c85b89402d38f99768c4 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 385 404 1.1E-36 T 05-07-2017 IPR003004 GspF/PilC family K08M4_RS14235 c1d0a743dba1c85b89402d38f99768c4 406 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 166 194 - T 05-07-2017 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 K08M4_RS14235 c1d0a743dba1c85b89402d38f99768c4 406 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 403 4.5E-156 T 05-07-2017 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 K08M4_RS14235 c1d0a743dba1c85b89402d38f99768c4 406 Pfam PF00482 Type II secretion system (T2SS), protein F 72 194 3.5E-33 T 05-07-2017 IPR018076 Type II secretion system F domain K08M4_RS14235 c1d0a743dba1c85b89402d38f99768c4 406 Pfam PF00482 Type II secretion system (T2SS), protein F 274 396 2.9E-25 T 05-07-2017 IPR018076 Type II secretion system F domain K08M4_RS08410 e4fac9ffb3b6e38cffe129245110604a 512 Gene3D G3DSA:3.30.70.270 357 510 4.2E-41 T 05-07-2017 K08M4_RS08410 e4fac9ffb3b6e38cffe129245110604a 512 SMART SM01079 78 273 4.1E-25 T 05-07-2017 IPR006189 CHASE domain K08M4_RS08410 e4fac9ffb3b6e38cffe129245110604a 512 Pfam PF03924 CHASE domain 83 271 3.4E-26 T 05-07-2017 IPR006189 CHASE domain K08M4_RS08410 e4fac9ffb3b6e38cffe129245110604a 512 Pfam PF00990 Diguanylate cyclase, GGDEF domain 356 507 1.7E-34 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS08410 e4fac9ffb3b6e38cffe129245110604a 512 SUPERFAMILY SSF55073 361 510 1.26E-35 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS08410 e4fac9ffb3b6e38cffe129245110604a 512 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 353 510 2.7E-35 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS08410 e4fac9ffb3b6e38cffe129245110604a 512 SMART SM00267 345 511 5.0E-41 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS17490 8e328202ca3bcfb943779572823e7c48 265 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 191 229 1.8E-4 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS17490 8e328202ca3bcfb943779572823e7c48 265 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 72 178 1.3E-23 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS17490 8e328202ca3bcfb943779572823e7c48 265 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 2 38 0.0017 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS14335 070a4bc7e9416c2ba3f82ff441e689de 463 SMART SM00729 58 278 3.9E-54 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 K08M4_RS14335 070a4bc7e9416c2ba3f82ff441e689de 463 SUPERFAMILY SSF102114 12 450 8.5E-144 T 05-07-2017 K08M4_RS14335 070a4bc7e9416c2ba3f82ff441e689de 463 PIRSF PIRSF000167 9 460 2.1E-170 T 05-07-2017 IPR004558 Coproporphyrinogen III oxidase, oxygen-independent, HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.99.22 K08M4_RS14335 070a4bc7e9416c2ba3f82ff441e689de 463 Pfam PF04055 Radical SAM superfamily 63 233 2.2E-19 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS14335 070a4bc7e9416c2ba3f82ff441e689de 463 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 14 463 4.6E-207 T 05-07-2017 IPR004558 Coproporphyrinogen III oxidase, oxygen-independent, HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.99.22 K08M4_RS14335 070a4bc7e9416c2ba3f82ff441e689de 463 Gene3D G3DSA:3.80.30.20 59 283 3.6E-32 T 05-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe K08M4_RS14335 070a4bc7e9416c2ba3f82ff441e689de 463 Pfam PF06969 HemN C-terminal domain 369 437 2.3E-9 T 05-07-2017 IPR010723 HemN, C-terminal K08M4_RS16085 a8d1524af4c452ccb08bca0754770f53 262 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 242 258 8.7E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS16085 a8d1524af4c452ccb08bca0754770f53 262 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 227 242 8.7E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS16085 a8d1524af4c452ccb08bca0754770f53 262 Gene3D G3DSA:1.10.10.60 156 212 9.6E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS16085 a8d1524af4c452ccb08bca0754770f53 262 SUPERFAMILY SSF51182 19 185 1.22E-9 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS16085 a8d1524af4c452ccb08bca0754770f53 262 Gene3D G3DSA:1.10.10.60 213 260 1.6E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS16085 a8d1524af4c452ccb08bca0754770f53 262 SUPERFAMILY SSF46689 213 260 3.58E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS16085 a8d1524af4c452ccb08bca0754770f53 262 SMART SM00342 176 258 1.8E-22 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS16085 a8d1524af4c452ccb08bca0754770f53 262 Pfam PF12833 Helix-turn-helix domain 182 260 2.7E-20 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS16085 a8d1524af4c452ccb08bca0754770f53 262 Gene3D G3DSA:2.60.120.10 21 86 5.2E-6 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS05465 bb6993c6739514339d36e333659b3ee6 445 Pfam PF17193 MukF C-terminal domain 288 445 5.2E-76 T 05-07-2017 IPR033441 Chromosome partition protein MukF, C-terminal domain K08M4_RS05465 bb6993c6739514339d36e333659b3ee6 445 Gene3D G3DSA:1.10.10.10 29 123 3.3E-44 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05465 bb6993c6739514339d36e333659b3ee6 445 Pfam PF03882 MukF winged-helix domain 10 122 2.9E-53 T 05-07-2017 IPR033439 Chromosome partition protein MukF, winged-helix domain K08M4_RS05465 bb6993c6739514339d36e333659b3ee6 445 PIRSF PIRSF018282 1 445 3.3E-245 T 05-07-2017 IPR005582 Chromosome partition protein MukF GO:0005509|GO:0006260|GO:0007059 K08M4_RS05465 bb6993c6739514339d36e333659b3ee6 445 Hamap MF_01803 Chromosome partition protein MukF [mukF]. 6 445 54.06 T 05-07-2017 IPR005582 Chromosome partition protein MukF GO:0005509|GO:0006260|GO:0007059 K08M4_RS05465 bb6993c6739514339d36e333659b3ee6 445 SUPERFAMILY SSF46785 13 123 2.45E-44 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05465 bb6993c6739514339d36e333659b3ee6 445 Pfam PF17192 MukF middle domain 126 286 2.2E-78 T 05-07-2017 IPR033440 Chromosome partition protein MukF, middle domain K08M4_RS05465 bb6993c6739514339d36e333659b3ee6 445 SUPERFAMILY SSF140570 124 286 1.03E-76 T 05-07-2017 IPR033440 Chromosome partition protein MukF, middle domain K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 SUPERFAMILY SSF103190 49 186 1.33E-27 T 05-07-2017 IPR029151 Periplasmic sensor domain-like K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 Gene3D G3DSA:3.30.565.10 444 595 3.2E-29 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 581 594 5.8E-14 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 542 5.8E-14 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 556 5.8E-14 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 557 575 5.8E-14 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 Pfam PF02743 Cache domain 44 227 2.4E-13 T 05-07-2017 IPR033479 Double Cache domain 1 K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 SUPERFAMILY SSF47384 358 437 5.69E-12 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 Pfam PF00512 His Kinase A (phospho-acceptor) domain 373 438 1.2E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 Gene3D G3DSA:1.10.287.130 372 436 2.5E-8 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 SUPERFAMILY SSF55874 438 599 1.44E-28 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 SMART SM00387 483 597 6.3E-21 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 PIRSF PIRSF036431 1 602 2.9E-182 T 05-07-2017 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 485 594 1.0E-14 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 Gene3D G3DSA:3.30.450.20 59 179 2.9E-4 T 05-07-2017 K08M4_RS10400 ee336b93cc84031b1cd925754d570361 602 SMART SM00388 372 440 1.5E-9 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS14155 3994326669684d33fe5b027e259fc8da 160 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 05-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 K08M4_RS14155 3994326669684d33fe5b027e259fc8da 160 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 2 157 5.4E-71 T 05-07-2017 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 K08M4_RS14155 3994326669684d33fe5b027e259fc8da 160 SUPERFAMILY SSF54534 80 156 4.97E-20 T 05-07-2017 K08M4_RS14155 3994326669684d33fe5b027e259fc8da 160 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 81 156 2.3E-23 T 05-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 K08M4_RS14155 3994326669684d33fe5b027e259fc8da 160 Hamap MF_00930 Transcription elongation factor GreB [greB]. 1 157 51.06 T 05-07-2017 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 K08M4_RS14155 3994326669684d33fe5b027e259fc8da 160 SUPERFAMILY SSF46557 3 78 1.57E-25 T 05-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 K08M4_RS14155 3994326669684d33fe5b027e259fc8da 160 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 155 26.765 T 05-07-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 K08M4_RS14155 3994326669684d33fe5b027e259fc8da 160 Pfam PF03449 Transcription elongation factor, N-terminal 5 73 1.4E-22 T 05-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 K08M4_RS14155 3994326669684d33fe5b027e259fc8da 160 Gene3D G3DSA:3.10.50.30 76 156 1.5E-27 T 05-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 K08M4_RS14155 3994326669684d33fe5b027e259fc8da 160 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 120 136 - T 05-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 K08M4_RS14155 3994326669684d33fe5b027e259fc8da 160 Gene3D G3DSA:1.10.287.180 1 75 5.6E-22 T 05-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 K08M4_RS14155 3994326669684d33fe5b027e259fc8da 160 PIRSF PIRSF006092 1 158 6.5E-42 T 05-07-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 K08M4_RS20410 32229cba9666820124f6f139aa5273cd 651 Gene3D G3DSA:3.20.20.450 399 642 2.9E-83 T 05-07-2017 IPR001633 EAL domain K08M4_RS20410 32229cba9666820124f6f139aa5273cd 651 SUPERFAMILY SSF141868 401 644 1.2E-76 T 05-07-2017 IPR001633 EAL domain K08M4_RS20410 32229cba9666820124f6f139aa5273cd 651 SMART SM00267 217 385 2.9E-49 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS20410 32229cba9666820124f6f139aa5273cd 651 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 227 383 1.8E-35 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS20410 32229cba9666820124f6f139aa5273cd 651 SUPERFAMILY SSF55073 233 386 4.55E-42 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS20410 32229cba9666820124f6f139aa5273cd 651 Pfam PF00990 Diguanylate cyclase, GGDEF domain 228 381 4.1E-40 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS20410 32229cba9666820124f6f139aa5273cd 651 SMART SM00052 395 638 2.1E-85 T 05-07-2017 IPR001633 EAL domain K08M4_RS20410 32229cba9666820124f6f139aa5273cd 651 Pfam PF00563 EAL domain 402 633 3.0E-66 T 05-07-2017 IPR001633 EAL domain K08M4_RS20410 32229cba9666820124f6f139aa5273cd 651 Gene3D G3DSA:3.30.70.270 229 390 4.8E-46 T 05-07-2017 K08M4_RS02595 b68e0d80775cb125e1a10b1ebec4ca6b 414 Gene3D G3DSA:3.40.190.10 162 339 9.9E-47 T 05-07-2017 K08M4_RS02595 b68e0d80775cb125e1a10b1ebec4ca6b 414 Pfam PF13416 Bacterial extracellular solute-binding protein 55 352 1.5E-31 T 05-07-2017 K08M4_RS02595 b68e0d80775cb125e1a10b1ebec4ca6b 414 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 143 160 - T 05-07-2017 IPR006061 Solute-binding family 1, conserved site GO:0005215|GO:0006810 K08M4_RS02595 b68e0d80775cb125e1a10b1ebec4ca6b 414 SUPERFAMILY SSF53850 39 407 2.27E-65 T 05-07-2017 K08M4_RS02595 b68e0d80775cb125e1a10b1ebec4ca6b 414 PRINTS PR00181 Maltose binding protein signature 245 264 2.7E-7 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS02595 b68e0d80775cb125e1a10b1ebec4ca6b 414 PRINTS PR00181 Maltose binding protein signature 369 388 2.7E-7 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS02595 b68e0d80775cb125e1a10b1ebec4ca6b 414 PRINTS PR00181 Maltose binding protein signature 140 159 2.7E-7 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS02595 b68e0d80775cb125e1a10b1ebec4ca6b 414 PRINTS PR00181 Maltose binding protein signature 161 180 2.7E-7 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS02595 b68e0d80775cb125e1a10b1ebec4ca6b 414 Gene3D G3DSA:3.40.190.10 38 161 1.1E-13 T 05-07-2017 K08M4_RS06630 40694b617254109dbadbfaeaa76b3caf 162 Gene3D G3DSA:3.40.630.30 1 161 1.3E-34 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS06630 40694b617254109dbadbfaeaa76b3caf 162 Pfam PF13420 Acetyltransferase (GNAT) domain 6 152 4.3E-14 T 05-07-2017 K08M4_RS06630 40694b617254109dbadbfaeaa76b3caf 162 SUPERFAMILY SSF55729 1 161 1.34E-32 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS14780 17d6a8b21ed56d03b9e2d09c2188b239 370 Gene3D G3DSA:3.40.50.450 113 257 2.8E-10 T 05-07-2017 K08M4_RS14780 17d6a8b21ed56d03b9e2d09c2188b239 370 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 73 284 1.5E-77 T 05-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 K08M4_RS14780 17d6a8b21ed56d03b9e2d09c2188b239 370 SUPERFAMILY SSF102405 85 285 1.57E-39 T 05-07-2017 K08M4_RS14780 17d6a8b21ed56d03b9e2d09c2188b239 370 Pfam PF02481 DNA recombination-mediator protein A 73 278 3.0E-77 T 05-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 K08M4_RS15795 eebfe3e469a1cb7c9dd85541ec92cd73 162 Gene3D G3DSA:1.25.40.10 27 114 2.2E-18 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS15795 eebfe3e469a1cb7c9dd85541ec92cd73 162 Pfam PF08238 Sel1 repeat 71 86 2.0 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS15795 eebfe3e469a1cb7c9dd85541ec92cd73 162 Pfam PF08238 Sel1 repeat 20 54 0.035 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS15795 eebfe3e469a1cb7c9dd85541ec92cd73 162 Pfam PF08238 Sel1 repeat 89 114 0.0034 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS15795 eebfe3e469a1cb7c9dd85541ec92cd73 162 SUPERFAMILY SSF81901 35 115 3.53E-18 T 05-07-2017 K08M4_RS15795 eebfe3e469a1cb7c9dd85541ec92cd73 162 SMART SM00671 55 87 14.0 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS15795 eebfe3e469a1cb7c9dd85541ec92cd73 162 SMART SM00671 88 122 0.05 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS15795 eebfe3e469a1cb7c9dd85541ec92cd73 162 SMART SM00671 26 54 62.0 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS13500 40ba3d5785a315d709ccfab5c441ec07 438 SMART SM00788 4 431 2.4E-301 T 05-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 K08M4_RS13500 40ba3d5785a315d709ccfab5c441ec07 438 SUPERFAMILY SSF52540 3 434 7.86E-178 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13500 40ba3d5785a315d709ccfab5c441ec07 438 Gene3D G3DSA:3.40.440.10 196 266 1.2E-71 T 05-07-2017 K08M4_RS13500 40ba3d5785a315d709ccfab5c441ec07 438 Gene3D G3DSA:3.40.440.10 4 94 1.2E-71 T 05-07-2017 K08M4_RS13500 40ba3d5785a315d709ccfab5c441ec07 438 Gene3D G3DSA:1.10.300.10 103 195 1.1E-38 T 05-07-2017 K08M4_RS13500 40ba3d5785a315d709ccfab5c441ec07 438 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 05-07-2017 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 K08M4_RS13500 40ba3d5785a315d709ccfab5c441ec07 438 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 05-07-2017 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 K08M4_RS13500 40ba3d5785a315d709ccfab5c441ec07 438 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 431 2.4E-191 T 05-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 K08M4_RS13500 40ba3d5785a315d709ccfab5c441ec07 438 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 438 217.107 T 05-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 K08M4_RS13500 40ba3d5785a315d709ccfab5c441ec07 438 Gene3D G3DSA:3.90.170.10 267 431 8.0E-64 T 05-07-2017 K08M4_RS13500 40ba3d5785a315d709ccfab5c441ec07 438 Pfam PF00709 Adenylosuccinate synthetase 5 430 1.6E-176 T 05-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 K08M4_RS00440 c6a33a7d40e6173b16c170ab95927a44 238 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 196 209 2.8E-5 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS00440 c6a33a7d40e6173b16c170ab95927a44 238 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 2.8E-5 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS00440 c6a33a7d40e6173b16c170ab95927a44 238 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 166 2.8E-5 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS00440 c6a33a7d40e6173b16c170ab95927a44 238 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 118 199 3.4E-10 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS00440 c6a33a7d40e6173b16c170ab95927a44 238 SUPERFAMILY SSF56784 9 236 2.94E-39 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS00440 c6a33a7d40e6173b16c170ab95927a44 238 Pfam PF13419 Haloacid dehalogenase-like hydrolase 15 206 5.7E-13 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS00440 c6a33a7d40e6173b16c170ab95927a44 238 Gene3D G3DSA:3.40.50.1000 9 235 2.2E-29 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS13880 f62be29b4cbcbf1a9d4ffe509a6410d9 155 Pfam PF02556 Preprotein translocase subunit SecB 7 145 7.7E-55 T 05-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 K08M4_RS13880 f62be29b4cbcbf1a9d4ffe509a6410d9 155 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 8 147 7.2E-58 T 05-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 K08M4_RS13880 f62be29b4cbcbf1a9d4ffe509a6410d9 155 Hamap MF_00821 Protein-export protein SecB [secB]. 1 147 31.541 T 05-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 K08M4_RS13880 f62be29b4cbcbf1a9d4ffe509a6410d9 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 125 143 7.6E-39 T 05-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 K08M4_RS13880 f62be29b4cbcbf1a9d4ffe509a6410d9 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 75 95 7.6E-39 T 05-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 K08M4_RS13880 f62be29b4cbcbf1a9d4ffe509a6410d9 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 99 121 7.6E-39 T 05-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 K08M4_RS13880 f62be29b4cbcbf1a9d4ffe509a6410d9 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 15 32 7.6E-39 T 05-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 K08M4_RS13880 f62be29b4cbcbf1a9d4ffe509a6410d9 155 Gene3D G3DSA:3.10.420.10 5 153 8.8E-60 T 05-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 K08M4_RS13880 f62be29b4cbcbf1a9d4ffe509a6410d9 155 SUPERFAMILY SSF54611 3 143 3.49E-52 T 05-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 K08M4_RS03180 bf65d8b6b975840700ab326d518ebecb 189 SUPERFAMILY SSF55718 47 154 2.24E-21 T 05-07-2017 IPR003033 SCP2 sterol-binding domain K08M4_RS03180 bf65d8b6b975840700ab326d518ebecb 189 Gene3D G3DSA:3.30.1050.10 69 150 7.6E-13 T 05-07-2017 IPR003033 SCP2 sterol-binding domain K08M4_RS03180 bf65d8b6b975840700ab326d518ebecb 189 PIRSF PIRSF025550 15 188 7.7E-84 T 05-07-2017 IPR016830 Uncharacterised conserved protein UCP025550, lipid carrier protein, YhbT K08M4_RS03180 bf65d8b6b975840700ab326d518ebecb 189 Pfam PF02036 SCP-2 sterol transfer family 50 148 3.6E-19 T 05-07-2017 IPR003033 SCP2 sterol-binding domain K08M4_RS20845 b0d639aa434973d1d6bda219ea98d74a 256 SMART SM00382 34 253 3.6E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS20845 b0d639aa434973d1d6bda219ea98d74a 256 Gene3D G3DSA:3.40.50.300 9 243 9.8E-71 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20845 b0d639aa434973d1d6bda219ea98d74a 256 SUPERFAMILY SSF52540 9 242 1.87E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20845 b0d639aa434973d1d6bda219ea98d74a 256 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS20845 b0d639aa434973d1d6bda219ea98d74a 256 Pfam PF00005 ABC transporter 25 181 2.6E-36 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS20845 b0d639aa434973d1d6bda219ea98d74a 256 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 9 250 7.2E-96 T 05-07-2017 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 K08M4_RS01445 30e2a48e87c18b6004c31da9bb294258 156 PIRSF PIRSF002122 3 156 2.9E-63 T 05-07-2017 IPR000235 Ribosomal protein S5/S7 GO:0006412 K08M4_RS01445 30e2a48e87c18b6004c31da9bb294258 156 SUPERFAMILY SSF47973 6 149 7.59E-59 T 05-07-2017 IPR023798 Ribosomal protein S7 domain K08M4_RS01445 30e2a48e87c18b6004c31da9bb294258 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 3.1E-65 T 05-07-2017 IPR023798 Ribosomal protein S7 domain K08M4_RS01445 30e2a48e87c18b6004c31da9bb294258 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.617 T 05-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 K08M4_RS01445 30e2a48e87c18b6004c31da9bb294258 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.2E-70 T 05-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 K08M4_RS01445 30e2a48e87c18b6004c31da9bb294258 156 Gene3D G3DSA:1.10.455.10 8 156 4.0E-68 T 05-07-2017 IPR023798 Ribosomal protein S7 domain K08M4_RS01445 30e2a48e87c18b6004c31da9bb294258 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 05-07-2017 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS16605 c2a625759d8e51e5adaec98500131338 153 SUPERFAMILY SSF46785 1 54 1.98E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16605 c2a625759d8e51e5adaec98500131338 153 Pfam PF01037 Lrp/AsnC ligand binding domain 77 140 4.5E-12 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS16605 c2a625759d8e51e5adaec98500131338 153 SUPERFAMILY SSF54909 62 144 8.98E-15 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel K08M4_RS16605 c2a625759d8e51e5adaec98500131338 153 Gene3D G3DSA:3.30.70.920 62 136 5.9E-15 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS16605 c2a625759d8e51e5adaec98500131338 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 7.6E-10 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS16605 c2a625759d8e51e5adaec98500131338 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 7.6E-10 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS16605 c2a625759d8e51e5adaec98500131338 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 7.6E-10 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS16605 c2a625759d8e51e5adaec98500131338 153 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 3.1E-15 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS16605 c2a625759d8e51e5adaec98500131338 153 Gene3D G3DSA:1.10.10.10 1 52 1.3E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16605 c2a625759d8e51e5adaec98500131338 153 SMART SM00344 1 111 1.2E-17 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 K08M4_RS18200 785b5281e5b13792f8c92a09bbb70493 198 Gene3D G3DSA:3.40.30.10 112 184 3.1E-4 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS18200 785b5281e5b13792f8c92a09bbb70493 198 Pfam PF13778 Domain of unknown function (DUF4174) 82 188 1.6E-23 T 05-07-2017 IPR025232 Domain of unknown function DUF4174 K08M4_RS14895 3ae420b4ea79cf1fb28bb36bddaa3055 403 Gene3D G3DSA:1.20.1250.20 197 376 1.6E-11 T 05-07-2017 K08M4_RS14895 3ae420b4ea79cf1fb28bb36bddaa3055 403 SUPERFAMILY SSF103473 6 376 6.93E-53 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS14895 3ae420b4ea79cf1fb28bb36bddaa3055 403 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 5 370 7.6E-85 T 05-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 K08M4_RS14895 3ae420b4ea79cf1fb28bb36bddaa3055 403 Pfam PF07690 Major Facilitator Superfamily 12 345 4.2E-36 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS14895 3ae420b4ea79cf1fb28bb36bddaa3055 403 Gene3D G3DSA:1.20.1250.20 8 189 2.8E-24 T 05-07-2017 K08M4_RS21750 7071614d94e63722c1e1e70bd3a8e409 299 Pfam PF03466 LysR substrate binding domain 95 277 8.5E-11 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS21750 7071614d94e63722c1e1e70bd3a8e409 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 6.4E-12 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS21750 7071614d94e63722c1e1e70bd3a8e409 299 Gene3D G3DSA:3.40.190.10 94 196 4.3E-6 T 05-07-2017 K08M4_RS21750 7071614d94e63722c1e1e70bd3a8e409 299 Gene3D G3DSA:3.40.190.10 199 260 8.4E-4 T 05-07-2017 K08M4_RS21750 7071614d94e63722c1e1e70bd3a8e409 299 SUPERFAMILY SSF53850 94 279 1.14E-14 T 05-07-2017 K08M4_RS21750 7071614d94e63722c1e1e70bd3a8e409 299 SUPERFAMILY SSF46785 2 79 9.8E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21750 7071614d94e63722c1e1e70bd3a8e409 299 Gene3D G3DSA:1.10.10.10 2 80 5.7E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05510 222e7bcf19b146c412f60ab332c6d32f 294 Pfam PF01904 Protein of unknown function DUF72 23 261 3.2E-55 T 05-07-2017 IPR002763 Protein of unknown function DUF72 K08M4_RS05510 222e7bcf19b146c412f60ab332c6d32f 294 SUPERFAMILY SSF117396 4 265 1.09E-72 T 05-07-2017 IPR002763 Protein of unknown function DUF72 K08M4_RS05510 222e7bcf19b146c412f60ab332c6d32f 294 Gene3D G3DSA:3.20.20.410 3 270 2.6E-72 T 05-07-2017 IPR002763 Protein of unknown function DUF72 K08M4_RS10080 bbde8593e15aa070bdcb8664a6443e8a 163 SUPERFAMILY SSF54593 1 155 2.95E-25 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS10080 bbde8593e15aa070bdcb8664a6443e8a 163 Gene3D G3DSA:3.10.180.10 1 156 1.2E-24 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS10080 bbde8593e15aa070bdcb8664a6443e8a 163 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 05-07-2017 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 K08M4_RS10080 bbde8593e15aa070bdcb8664a6443e8a 163 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 149 2.5E-13 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain K08M4_RS20835 31a73913d892b6cce41fda122ca0036b 267 SUPERFAMILY SSF161098 72 255 5.1E-35 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS20835 31a73913d892b6cce41fda122ca0036b 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 254 1.6E-11 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS20835 31a73913d892b6cce41fda122ca0036b 267 Gene3D G3DSA:1.10.3720.10 70 266 9.0E-28 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS20835 31a73913d892b6cce41fda122ca0036b 267 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 17 266 8.0E-85 T 05-07-2017 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 K08M4_RS14965 db14c8ac8b0e330fa199b9ebf314fca1 631 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 05-07-2017 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 K08M4_RS14965 db14c8ac8b0e330fa199b9ebf314fca1 631 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 622 8.1E-294 T 05-07-2017 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 K08M4_RS14965 db14c8ac8b0e330fa199b9ebf314fca1 631 Gene3D G3DSA:3.50.50.60 7 235 8.0E-53 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14965 db14c8ac8b0e330fa199b9ebf314fca1 631 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 624 42.533 T 05-07-2017 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 K08M4_RS14965 db14c8ac8b0e330fa199b9ebf314fca1 631 Pfam PF13932 GidA associated domain 403 616 2.3E-71 T 05-07-2017 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 K08M4_RS14965 db14c8ac8b0e330fa199b9ebf314fca1 631 Pfam PF01134 Glucose inhibited division protein A 8 399 3.7E-168 T 05-07-2017 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 K08M4_RS14965 db14c8ac8b0e330fa199b9ebf314fca1 631 SUPERFAMILY SSF51905 97 261 2.06E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14965 db14c8ac8b0e330fa199b9ebf314fca1 631 SUPERFAMILY SSF51905 5 66 2.06E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14965 db14c8ac8b0e330fa199b9ebf314fca1 631 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 05-07-2017 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 K08M4_RS14965 db14c8ac8b0e330fa199b9ebf314fca1 631 SMART SM01228 546 617 4.7E-42 T 05-07-2017 K08M4_RS11800 deb60573b22eb99e21339e32eadf336f 487 Pfam PF00571 CBS domain 152 201 6.4E-4 T 05-07-2017 IPR000644 CBS domain K08M4_RS11800 deb60573b22eb99e21339e32eadf336f 487 Pfam PF00571 CBS domain 95 140 3.6E-9 T 05-07-2017 IPR000644 CBS domain K08M4_RS11800 deb60573b22eb99e21339e32eadf336f 487 SMART SM00116 158 206 1.1E-5 T 05-07-2017 IPR000644 CBS domain K08M4_RS11800 deb60573b22eb99e21339e32eadf336f 487 SMART SM00116 96 144 5.7E-11 T 05-07-2017 IPR000644 CBS domain K08M4_RS11800 deb60573b22eb99e21339e32eadf336f 487 SUPERFAMILY SSF51412 217 477 1.31E-124 T 05-07-2017 K08M4_RS11800 deb60573b22eb99e21339e32eadf336f 487 SUPERFAMILY SSF51412 1 90 1.31E-124 T 05-07-2017 K08M4_RS11800 deb60573b22eb99e21339e32eadf336f 487 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 8 486 83.559 T 05-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 K08M4_RS11800 deb60573b22eb99e21339e32eadf336f 487 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 295 307 - T 05-07-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 K08M4_RS11800 deb60573b22eb99e21339e32eadf336f 487 SUPERFAMILY SSF54631 95 203 1.89E-24 T 05-07-2017 K08M4_RS11800 deb60573b22eb99e21339e32eadf336f 487 Gene3D G3DSA:3.20.20.70 2 485 8.9E-195 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS11800 deb60573b22eb99e21339e32eadf336f 487 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 8 473 3.5E-160 T 05-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 K08M4_RS11800 deb60573b22eb99e21339e32eadf336f 487 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 8 454 3.5E-193 T 05-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 K08M4_RS11800 deb60573b22eb99e21339e32eadf336f 487 SMART SM01240 7 473 0.0 T 05-07-2017 K08M4_RS11800 deb60573b22eb99e21339e32eadf336f 487 PIRSF PIRSF000130 1 487 2.1E-198 T 05-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 SUPERFAMILY SSF53738 178 285 8.24E-26 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 Gene3D G3DSA:3.30.310.50 399 475 8.1E-15 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 10 143 9.7E-34 T 05-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 SUPERFAMILY SSF53738 287 390 8.83E-31 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 Gene3D G3DSA:3.40.120.10 279 391 7.0E-37 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 246 2.2E-27 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 262 277 2.2E-27 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 103 117 2.2E-27 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 194 213 2.2E-27 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 402 473 1.1E-11 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 SUPERFAMILY SSF53738 6 201 7.46E-36 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 287 397 2.7E-24 T 05-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 Gene3D G3DSA:3.40.120.10 10 134 7.1E-35 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 SUPERFAMILY SSF55957 397 477 5.23E-16 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 104 113 - T 05-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 178 282 7.8E-20 T 05-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS16840 95d237324841a38111ccbe337d7199d8 479 Gene3D G3DSA:3.40.120.10 196 278 1.0E-25 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS15140 e28cdafc9eb8b2329ff0924962269003 211 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 1 211 3.1E-88 T 05-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 K08M4_RS15140 e28cdafc9eb8b2329ff0924962269003 211 Gene3D G3DSA:2.30.110.10 15 211 1.1E-80 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 K08M4_RS15140 e28cdafc9eb8b2329ff0924962269003 211 PIRSF PIRSF000190 1 211 2.7E-80 T 05-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 K08M4_RS15140 e28cdafc9eb8b2329ff0924962269003 211 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 181 194 - T 05-07-2017 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 K08M4_RS15140 e28cdafc9eb8b2329ff0924962269003 211 SUPERFAMILY SSF50475 14 211 6.17E-64 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 K08M4_RS15140 e28cdafc9eb8b2329ff0924962269003 211 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 33 116 1.2E-23 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 K08M4_RS15140 e28cdafc9eb8b2329ff0924962269003 211 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 171 211 4.5E-18 T 05-07-2017 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 K08M4_RS15140 e28cdafc9eb8b2329ff0924962269003 211 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 9 211 37.267 T 05-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 K08M4_RS01625 0b44af947671c0ff96e691448cb91ca1 188 Pfam PF00027 Cyclic nucleotide-binding domain 30 112 1.3E-8 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain K08M4_RS01625 0b44af947671c0ff96e691448cb91ca1 188 Gene3D G3DSA:2.60.120.10 4 152 2.2E-29 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS01625 0b44af947671c0ff96e691448cb91ca1 188 SUPERFAMILY SSF51206 16 136 1.26E-20 T 05-07-2017 IPR018490 Cyclic nucleotide-binding-like K08M4_RS15350 a5b1b09aa41ee61c26461b312c8b7e85 399 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 13 114 7.3E-25 T 05-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain K08M4_RS15350 a5b1b09aa41ee61c26461b312c8b7e85 399 Gene3D G3DSA:3.20.20.120 120 366 2.1E-67 T 05-07-2017 IPR029065 Enolase C-terminal domain-like K08M4_RS15350 a5b1b09aa41ee61c26461b312c8b7e85 399 SUPERFAMILY SSF51604 102 379 2.23E-67 T 05-07-2017 IPR029065 Enolase C-terminal domain-like K08M4_RS15350 a5b1b09aa41ee61c26461b312c8b7e85 399 Pfam PF13378 Enolase C-terminal domain-like 181 372 1.5E-37 T 05-07-2017 IPR029065 Enolase C-terminal domain-like K08M4_RS15350 a5b1b09aa41ee61c26461b312c8b7e85 399 SMART SM00922 132 252 8.1E-7 T 05-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal K08M4_RS15350 a5b1b09aa41ee61c26461b312c8b7e85 399 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 89 114 - T 05-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 K08M4_RS15350 a5b1b09aa41ee61c26461b312c8b7e85 399 SUPERFAMILY SSF54826 15 116 6.48E-29 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS15350 a5b1b09aa41ee61c26461b312c8b7e85 399 Gene3D G3DSA:3.30.390.10 15 119 4.9E-43 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS13695 14c815c4ae2ecff74249e4e44bdba659 340 TIGRFAM TIGR00238 TIGR00238: KamA family protein 11 328 8.4E-127 T 05-07-2017 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase K08M4_RS13695 14c815c4ae2ecff74249e4e44bdba659 340 SUPERFAMILY SSF102114 102 320 1.83E-22 T 05-07-2017 K08M4_RS13695 14c815c4ae2ecff74249e4e44bdba659 340 Gene3D G3DSA:3.20.20.70 105 308 4.1E-14 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS13695 14c815c4ae2ecff74249e4e44bdba659 340 TIGRFAM TIGR03821 EFP_modif_epmB: EF-P beta-lysylation protein EpmB 16 335 3.8E-152 T 05-07-2017 IPR022462 Lysine-2,3-aminomutase-like K08M4_RS13695 14c815c4ae2ecff74249e4e44bdba659 340 PIRSF PIRSF004911 3 340 6.3E-115 T 05-07-2017 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase K08M4_RS13695 14c815c4ae2ecff74249e4e44bdba659 340 Pfam PF04055 Radical SAM superfamily 117 231 1.1E-9 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS13695 14c815c4ae2ecff74249e4e44bdba659 340 Pfam PF13353 4Fe-4S single cluster domain 114 183 1.5E-6 T 05-07-2017 K08M4_RS11010 3451b6074443b9176befc081f60371d2 180 SUPERFAMILY SSF55021 1 83 1.06E-16 T 05-07-2017 K08M4_RS11010 3451b6074443b9176befc081f60371d2 180 PIRSF PIRSF028103 1 178 6.4E-64 T 05-07-2017 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 K08M4_RS11010 3451b6074443b9176befc081f60371d2 180 Pfam PF13740 ACT domain 3 78 8.0E-24 T 05-07-2017 K08M4_RS11010 3451b6074443b9176befc081f60371d2 180 Gene3D G3DSA:3.30.70.260 88 179 1.7E-37 T 05-07-2017 K08M4_RS11010 3451b6074443b9176befc081f60371d2 180 Gene3D G3DSA:3.30.70.260 1 84 9.4E-27 T 05-07-2017 K08M4_RS11010 3451b6074443b9176befc081f60371d2 180 SUPERFAMILY SSF55021 89 176 3.27E-21 T 05-07-2017 K08M4_RS05985 c32a05c4a94c180ceeea4442701ad7a2 367 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 19 342 20.509 T 05-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 K08M4_RS05985 c32a05c4a94c180ceeea4442701ad7a2 367 Gene3D G3DSA:3.30.200.20 13 135 1.0E-32 T 05-07-2017 K08M4_RS05985 c32a05c4a94c180ceeea4442701ad7a2 367 Gene3D G3DSA:3.30.470.20 136 282 2.5E-41 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS05985 c32a05c4a94c180ceeea4442701ad7a2 367 SUPERFAMILY SSF56104 14 345 1.8E-65 T 05-07-2017 K08M4_RS05985 c32a05c4a94c180ceeea4442701ad7a2 367 Pfam PF01259 SAICAR synthetase 22 294 5.5E-48 T 05-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 K08M4_RS05985 c32a05c4a94c180ceeea4442701ad7a2 367 TIGRFAM TIGR02735 purC_vibrio: phosphoribosylaminoimidazole-succinocarboxamide synthase 2 366 2.0E-215 T 05-07-2017 IPR014106 Phosphoribosylaminoimidazole-succinocarboxamide synthase, Vibrio-type GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 K08M4_RS20190 1e65e4866858760b008cab3610d610d6 351 Pfam PF01032 FecCD transport family 47 348 4.8E-82 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 K08M4_RS20190 1e65e4866858760b008cab3610d610d6 351 SUPERFAMILY SSF81345 28 349 3.27E-74 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS20190 1e65e4866858760b008cab3610d610d6 351 Gene3D G3DSA:1.10.3470.10 31 350 7.4E-89 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS21255 73b52924276469bfaddfd0a5995f3912 328 Gene3D G3DSA:1.10.3720.10 24 316 3.8E-58 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS21255 73b52924276469bfaddfd0a5995f3912 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 311 3.0E-7 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS21255 73b52924276469bfaddfd0a5995f3912 328 SUPERFAMILY SSF161098 71 314 6.28E-54 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS03030 55b57b12deaffab9c034c7283ce7c6ae 374 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 78 276 1.3E-19 T 05-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain K08M4_RS03030 55b57b12deaffab9c034c7283ce7c6ae 374 Gene3D G3DSA:2.40.50.100 83 113 2.4E-16 T 05-07-2017 K08M4_RS03030 55b57b12deaffab9c034c7283ce7c6ae 374 Gene3D G3DSA:2.40.50.100 174 206 2.4E-16 T 05-07-2017 K08M4_RS03030 55b57b12deaffab9c034c7283ce7c6ae 374 SUPERFAMILY SSF111369 68 283 1.96E-30 T 05-07-2017 K08M4_RS03030 55b57b12deaffab9c034c7283ce7c6ae 374 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 56 359 1.3E-45 T 05-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 K08M4_RS02200 042db622f273e1954ae71cfc165e2878 166 Hamap MF_00746 Protein SprT [sprT]. 8 161 41.302 T 05-07-2017 IPR023483 Uncharacterised protein family SprT K08M4_RS02200 042db622f273e1954ae71cfc165e2878 166 Pfam PF10263 SprT-like family 16 159 1.1E-28 T 05-07-2017 IPR006640 SprT-like K08M4_RS02200 042db622f273e1954ae71cfc165e2878 166 SMART SM00731 12 161 1.0E-56 T 05-07-2017 IPR006640 SprT-like K08M4_RS06115 5637f71671bc9efb45964177e1895b92 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 63 17.381 T 05-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 K08M4_RS06115 5637f71671bc9efb45964177e1895b92 64 SUPERFAMILY SSF143034 2 63 2.35E-20 T 05-07-2017 K08M4_RS06115 5637f71671bc9efb45964177e1895b92 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 30 - T 05-07-2017 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS06115 5637f71671bc9efb45964177e1895b92 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 5.2E-26 T 05-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 K08M4_RS06115 5637f71671bc9efb45964177e1895b92 64 PRINTS PR00064 Ribosomal protein L35 signature 35 53 2.3E-18 T 05-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 K08M4_RS06115 5637f71671bc9efb45964177e1895b92 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 2.3E-18 T 05-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 K08M4_RS06115 5637f71671bc9efb45964177e1895b92 64 PRINTS PR00064 Ribosomal protein L35 signature 20 34 2.3E-18 T 05-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 K08M4_RS06115 5637f71671bc9efb45964177e1895b92 64 Pfam PF01632 Ribosomal protein L35 2 61 1.9E-21 T 05-07-2017 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS02330 d4e63390677801ac314af7625d3e3134 358 PIRSF PIRSF001359 13 358 3.8E-91 T 05-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 K08M4_RS02330 d4e63390677801ac314af7625d3e3134 358 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 171 182 - T 05-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 K08M4_RS02330 d4e63390677801ac314af7625d3e3134 358 SUPERFAMILY SSF51569 4 356 2.38E-125 T 05-07-2017 K08M4_RS02330 d4e63390677801ac314af7625d3e3134 358 Pfam PF01116 Fructose-bisphosphate aldolase class-II 17 354 1.2E-87 T 05-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 K08M4_RS02330 d4e63390677801ac314af7625d3e3134 358 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 100 111 - T 05-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 K08M4_RS02330 d4e63390677801ac314af7625d3e3134 358 Gene3D G3DSA:3.20.20.70 11 355 2.2E-120 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS02330 d4e63390677801ac314af7625d3e3134 358 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 14 356 3.4E-107 T 05-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 K08M4_RS02330 d4e63390677801ac314af7625d3e3134 358 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 4 357 7.3E-173 T 05-07-2017 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 K08M4_RS09035 a0982164f81bc1505610d228174e0149 419 Pfam PF09375 Imelysin 39 397 2.1E-95 T 05-07-2017 K08M4_RS16185 0483e70d61b98f291bd4a133d532ab11 262 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 12 206 1.7E-12 T 05-07-2017 IPR008775 Phytanoyl-CoA dioxygenase K08M4_RS16185 0483e70d61b98f291bd4a133d532ab11 262 Gene3D G3DSA:2.60.120.620 5 227 9.8E-26 T 05-07-2017 K08M4_RS16185 0483e70d61b98f291bd4a133d532ab11 262 SUPERFAMILY SSF51197 6 243 3.75E-34 T 05-07-2017 K08M4_RS08725 a8fd70d60f6f722db1133cae7367de01 478 SUPERFAMILY SSF51735 1 293 4.35E-39 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS08725 a8fd70d60f6f722db1133cae7367de01 478 Pfam PF11066 Protein of unknown function (DUF2867) 332 464 5.8E-14 T 05-07-2017 IPR021295 Protein of unknown function DUF2867 K08M4_RS08725 a8fd70d60f6f722db1133cae7367de01 478 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 120 2.5E-10 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 K08M4_RS08725 a8fd70d60f6f722db1133cae7367de01 478 Gene3D G3DSA:3.40.50.720 1 220 1.3E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS18635 da22b053e61a58425b30aaaaa8369d5e 635 SUPERFAMILY SSF141868 379 628 1.23E-83 T 05-07-2017 IPR001633 EAL domain K08M4_RS18635 da22b053e61a58425b30aaaaa8369d5e 635 SMART SM00065 14 161 2.4E-9 T 05-07-2017 IPR003018 GAF domain GO:0005515 K08M4_RS18635 da22b053e61a58425b30aaaaa8369d5e 635 Gene3D G3DSA:3.30.70.270 204 368 1.3E-17 T 05-07-2017 K08M4_RS18635 da22b053e61a58425b30aaaaa8369d5e 635 Pfam PF00990 Diguanylate cyclase, GGDEF domain 204 358 6.6E-17 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS18635 da22b053e61a58425b30aaaaa8369d5e 635 SUPERFAMILY SSF55073 209 361 3.45E-15 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS18635 da22b053e61a58425b30aaaaa8369d5e 635 Pfam PF00563 EAL domain 381 613 1.6E-67 T 05-07-2017 IPR001633 EAL domain K08M4_RS18635 da22b053e61a58425b30aaaaa8369d5e 635 Gene3D G3DSA:3.30.450.40 14 166 1.8E-11 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS18635 da22b053e61a58425b30aaaaa8369d5e 635 SMART SM00052 373 618 1.5E-95 T 05-07-2017 IPR001633 EAL domain K08M4_RS18635 da22b053e61a58425b30aaaaa8369d5e 635 Gene3D G3DSA:3.20.20.450 377 626 8.2E-88 T 05-07-2017 IPR001633 EAL domain K08M4_RS18635 da22b053e61a58425b30aaaaa8369d5e 635 SMART SM00267 192 363 2.6E-6 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS18635 da22b053e61a58425b30aaaaa8369d5e 635 Pfam PF01590 GAF domain 19 147 4.7E-8 T 05-07-2017 IPR003018 GAF domain GO:0005515 K08M4_RS18635 da22b053e61a58425b30aaaaa8369d5e 635 SUPERFAMILY SSF55781 16 163 2.84E-19 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS14865 da53a186adb54841ed8b7cb01f0fbeb5 548 Gene3D G3DSA:3.40.50.970 1 174 8.2E-73 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS14865 da53a186adb54841ed8b7cb01f0fbeb5 548 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 412 431 - T 05-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 K08M4_RS14865 da53a186adb54841ed8b7cb01f0fbeb5 548 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 168 1.3E-55 T 05-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 K08M4_RS14865 da53a186adb54841ed8b7cb01f0fbeb5 548 Gene3D G3DSA:3.40.50.1220 180 341 5.2E-54 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain K08M4_RS14865 da53a186adb54841ed8b7cb01f0fbeb5 548 SUPERFAMILY SSF52518 1 177 1.16E-62 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS14865 da53a186adb54841ed8b7cb01f0fbeb5 548 SUPERFAMILY SSF52467 184 342 5.51E-55 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain K08M4_RS14865 da53a186adb54841ed8b7cb01f0fbeb5 548 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 1 546 6.7E-209 T 05-07-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 K08M4_RS14865 da53a186adb54841ed8b7cb01f0fbeb5 548 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 187 322 2.4E-40 T 05-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 K08M4_RS14865 da53a186adb54841ed8b7cb01f0fbeb5 548 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 375 523 1.3E-47 T 05-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 K08M4_RS14865 da53a186adb54841ed8b7cb01f0fbeb5 548 SUPERFAMILY SSF52518 358 546 3.69E-63 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS14865 da53a186adb54841ed8b7cb01f0fbeb5 548 Gene3D G3DSA:3.40.50.970 345 546 1.6E-69 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS03805 bbf8d8c9f0689670ef9a84fd17c618ca 419 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 170 304 2.1E-49 T 05-07-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase K08M4_RS03805 bbf8d8c9f0689670ef9a84fd17c618ca 419 SUPERFAMILY SSF51735 161 313 2.08E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS03805 bbf8d8c9f0689670ef9a84fd17c618ca 419 Gene3D G3DSA:3.40.50.720 182 356 9.1E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS03805 bbf8d8c9f0689670ef9a84fd17c618ca 419 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 154 7.3E-52 T 05-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 K08M4_RS03805 bbf8d8c9f0689670ef9a84fd17c618ca 419 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 415 7.6E-144 T 05-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 K08M4_RS03805 bbf8d8c9f0689670ef9a84fd17c618ca 419 SUPERFAMILY SSF69742 1 156 5.62E-48 T 05-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 K08M4_RS03805 bbf8d8c9f0689670ef9a84fd17c618ca 419 SUPERFAMILY SSF69075 315 416 5.62E-28 T 05-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 K08M4_RS03805 bbf8d8c9f0689670ef9a84fd17c618ca 419 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 318 413 5.8E-23 T 05-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 K08M4_RS03805 bbf8d8c9f0689670ef9a84fd17c618ca 419 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 97 120 - T 05-07-2017 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 K08M4_RS03805 bbf8d8c9f0689670ef9a84fd17c618ca 419 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 416 30.623 T 05-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 K08M4_RS03805 bbf8d8c9f0689670ef9a84fd17c618ca 419 PIRSF PIRSF000445 1 419 1.4E-155 T 05-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 K08M4_RS04830 273728727f95d0a3cb30f60ac545169b 441 PRINTS PR00173 Glutamate-aspartate symporter signature 374 393 1.0E-5 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS04830 273728727f95d0a3cb30f60ac545169b 441 PRINTS PR00173 Glutamate-aspartate symporter signature 20 40 1.0E-5 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS04830 273728727f95d0a3cb30f60ac545169b 441 Pfam PF03553 Na+/H+ antiporter family 150 435 4.8E-76 T 05-07-2017 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 K08M4_RS04830 273728727f95d0a3cb30f60ac545169b 441 Pfam PF13726 Na+-H+ antiporter family 2 88 1.1E-33 T 05-07-2017 IPR032813 Putative Na+/H+ antiporter, N-terminal K08M4_RS14525 28b37156c09f0c27a118a889aa86acc4 144 SUPERFAMILY SSF52402 3 139 2.43E-33 T 05-07-2017 K08M4_RS14525 28b37156c09f0c27a118a889aa86acc4 144 Gene3D G3DSA:3.40.50.620 3 139 2.5E-31 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS14525 28b37156c09f0c27a118a889aa86acc4 144 Pfam PF00582 Universal stress protein family 3 138 1.4E-22 T 05-07-2017 IPR006016 UspA GO:0006950 K08M4_RS14525 28b37156c09f0c27a118a889aa86acc4 144 PIRSF PIRSF006276 1 141 3.1E-52 T 05-07-2017 IPR006015 Universal stress protein A K08M4_RS20285 38af1a78cec87f30607d2277a82bb2de 244 Pfam PF00588 SpoU rRNA Methylase family 102 236 1.2E-29 T 05-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 K08M4_RS20285 38af1a78cec87f30607d2277a82bb2de 244 SUPERFAMILY SSF55315 4 93 6.12E-11 T 05-07-2017 IPR029064 50S ribosomal protein L30e-like K08M4_RS20285 38af1a78cec87f30607d2277a82bb2de 244 Gene3D G3DSA:3.30.1330.30 1 92 1.1E-23 T 05-07-2017 IPR029064 50S ribosomal protein L30e-like K08M4_RS20285 38af1a78cec87f30607d2277a82bb2de 244 Gene3D G3DSA:3.40.1280.10 99 243 9.4E-39 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal K08M4_RS20285 38af1a78cec87f30607d2277a82bb2de 244 SUPERFAMILY SSF75217 97 243 2.22E-34 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases K08M4_RS10930 dae71fa446becffaa3100b91520e1f69 307 Pfam PF04261 Dyp-type peroxidase family 12 300 3.0E-86 T 05-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 K08M4_RS10930 dae71fa446becffaa3100b91520e1f69 307 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 12 300 7.7E-82 T 05-07-2017 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 K08M4_RS10930 dae71fa446becffaa3100b91520e1f69 307 SUPERFAMILY SSF54909 10 303 5.18E-91 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel K08M4_RS11950 fe41636c450813fd8be1bb8b4657ffbb 337 Gene3D G3DSA:3.40.50.2300 51 166 4.1E-31 T 05-07-2017 K08M4_RS11950 fe41636c450813fd8be1bb8b4657ffbb 337 SMART SM00354 1 67 1.6E-17 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS11950 fe41636c450813fd8be1bb8b4657ffbb 337 SUPERFAMILY SSF47413 1 49 7.74E-13 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS11950 fe41636c450813fd8be1bb8b4657ffbb 337 SUPERFAMILY SSF53822 55 302 8.78E-43 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS11950 fe41636c450813fd8be1bb8b4657ffbb 337 Gene3D G3DSA:1.10.260.40 1 45 2.0E-18 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS11950 fe41636c450813fd8be1bb8b4657ffbb 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 12 22 1.1E-6 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS11950 fe41636c450813fd8be1bb8b4657ffbb 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 2 12 1.1E-6 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS11950 fe41636c450813fd8be1bb8b4657ffbb 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 3 21 - T 05-07-2017 K08M4_RS11950 fe41636c450813fd8be1bb8b4657ffbb 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 2 45 6.5E-17 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS11950 fe41636c450813fd8be1bb8b4657ffbb 337 Pfam PF13377 Periplasmic binding protein-like domain 163 317 8.0E-15 T 05-07-2017 K08M4_RS11950 fe41636c450813fd8be1bb8b4657ffbb 337 Gene3D G3DSA:3.40.50.2300 167 298 1.5E-20 T 05-07-2017 K08M4_RS00560 dda747e411bee1163ce6ab764309cecf 225 SUPERFAMILY SSF52540 1 220 1.21E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00560 dda747e411bee1163ce6ab764309cecf 225 Gene3D G3DSA:3.40.50.300 1 201 9.9E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00560 dda747e411bee1163ce6ab764309cecf 225 Pfam PF00005 ABC transporter 18 165 1.8E-35 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS00560 dda747e411bee1163ce6ab764309cecf 225 SMART SM00382 27 215 3.5E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS00560 dda747e411bee1163ce6ab764309cecf 225 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 4.3E-89 T 05-07-2017 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 K08M4_RS00560 dda747e411bee1163ce6ab764309cecf 225 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS14025 e58698e009280e525c0b29af728f1880 413 Gene3D G3DSA:3.40.50.10300 198 411 7.8E-91 T 05-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 K08M4_RS14025 e58698e009280e525c0b29af728f1880 413 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 198 382 4.0E-77 T 05-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 K08M4_RS14025 e58698e009280e525c0b29af728f1880 413 SUPERFAMILY SSF52507 16 194 3.14E-61 T 05-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 K08M4_RS14025 e58698e009280e525c0b29af728f1880 413 Pfam PF02441 Flavoprotein 19 147 6.3E-32 T 05-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 K08M4_RS14025 e58698e009280e525c0b29af728f1880 413 SUPERFAMILY SSF102645 196 411 3.27E-79 T 05-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 K08M4_RS14025 e58698e009280e525c0b29af728f1880 413 Gene3D G3DSA:3.40.50.1950 16 197 2.1E-66 T 05-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 K08M4_RS14025 e58698e009280e525c0b29af728f1880 413 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 16 407 1.1E-152 T 05-07-2017 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 K08M4_RS19760 9b929ddaf5daf1c847bb58dd415e8523 205 SUPERFAMILY SSF51391 3 203 8.37E-66 T 05-07-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS19760 9b929ddaf5daf1c847bb58dd415e8523 205 Pfam PF02581 Thiamine monophosphate synthase/TENI 6 186 2.6E-63 T 05-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS19760 9b929ddaf5daf1c847bb58dd415e8523 205 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 4 204 27.272 T 05-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS19760 9b929ddaf5daf1c847bb58dd415e8523 205 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 5 198 2.0E-63 T 05-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS19760 9b929ddaf5daf1c847bb58dd415e8523 205 Gene3D G3DSA:3.20.20.70 3 203 4.0E-74 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS07950 91f71c59269bfe1ba65536aa8557bca7 435 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 21 429 3.1E-115 T 05-07-2017 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 K08M4_RS07950 91f71c59269bfe1ba65536aa8557bca7 435 Gene3D G3DSA:1.20.1600.10 20 418 2.0E-64 T 05-07-2017 K08M4_RS07950 91f71c59269bfe1ba65536aa8557bca7 435 Pfam PF02321 Outer membrane efflux protein 24 211 2.1E-22 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS07950 91f71c59269bfe1ba65536aa8557bca7 435 Pfam PF02321 Outer membrane efflux protein 232 415 8.2E-28 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS07950 91f71c59269bfe1ba65536aa8557bca7 435 SUPERFAMILY SSF56954 6 418 2.75E-85 T 05-07-2017 K08M4_RS12220 f26b8f393d50e9b81f5c4834e5fc238b 243 Gene3D G3DSA:2.20.25.10 223 242 6.7E-6 T 05-07-2017 K08M4_RS12220 f26b8f393d50e9b81f5c4834e5fc238b 243 Gene3D G3DSA:2.40.50.40 139 203 1.8E-7 T 05-07-2017 K08M4_RS12220 f26b8f393d50e9b81f5c4834e5fc238b 243 Pfam PF00072 Response regulator receiver domain 5 111 9.2E-20 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS12220 f26b8f393d50e9b81f5c4834e5fc238b 243 SUPERFAMILY SSF52172 1 124 8.4E-28 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS12220 f26b8f393d50e9b81f5c4834e5fc238b 243 Pfam PF04397 LytTr DNA-binding domain 148 240 2.5E-19 T 05-07-2017 IPR007492 LytTR DNA-binding domain GO:0003677 K08M4_RS12220 f26b8f393d50e9b81f5c4834e5fc238b 243 SMART SM00850 147 241 1.8E-21 T 05-07-2017 IPR007492 LytTR DNA-binding domain GO:0003677 K08M4_RS12220 f26b8f393d50e9b81f5c4834e5fc238b 243 Gene3D G3DSA:3.40.50.2300 1 124 1.2E-27 T 05-07-2017 K08M4_RS12220 f26b8f393d50e9b81f5c4834e5fc238b 243 SMART SM00448 2 112 7.2E-21 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS07765 ac2db0bf6b6e8e6006f32d06a74d4b57 550 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 317 333 1.2E-10 T 05-07-2017 K08M4_RS07765 ac2db0bf6b6e8e6006f32d06a74d4b57 550 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 460 478 1.2E-10 T 05-07-2017 K08M4_RS07765 ac2db0bf6b6e8e6006f32d06a74d4b57 550 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 430 449 1.2E-10 T 05-07-2017 K08M4_RS07765 ac2db0bf6b6e8e6006f32d06a74d4b57 550 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 400 419 1.2E-10 T 05-07-2017 K08M4_RS07765 ac2db0bf6b6e8e6006f32d06a74d4b57 550 Gene3D G3DSA:3.30.230.10 309 509 3.2E-32 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup K08M4_RS07765 ac2db0bf6b6e8e6006f32d06a74d4b57 550 SUPERFAMILY SSF54211 317 508 1.25E-33 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS07765 ac2db0bf6b6e8e6006f32d06a74d4b57 550 Pfam PF13654 AAA domain 9 291 2.1E-26 T 05-07-2017 K08M4_RS07765 ac2db0bf6b6e8e6006f32d06a74d4b57 550 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 403 507 6.4E-10 T 05-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 K08M4_RS00195 d48fc43a06228d005ab8ca57f3acf761 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 4.1E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS00195 d48fc43a06228d005ab8ca57f3acf761 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 4.1E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS00195 d48fc43a06228d005ab8ca57f3acf761 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 4.1E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS00195 d48fc43a06228d005ab8ca57f3acf761 313 Gene3D G3DSA:1.10.10.10 2 88 1.7E-28 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS00195 d48fc43a06228d005ab8ca57f3acf761 313 Gene3D G3DSA:3.40.190.10 284 307 2.1E-20 T 05-07-2017 K08M4_RS00195 d48fc43a06228d005ab8ca57f3acf761 313 Gene3D G3DSA:3.40.190.10 92 183 2.1E-20 T 05-07-2017 K08M4_RS00195 d48fc43a06228d005ab8ca57f3acf761 313 SUPERFAMILY SSF46785 7 86 3.96E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS00195 d48fc43a06228d005ab8ca57f3acf761 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 6.8E-17 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS00195 d48fc43a06228d005ab8ca57f3acf761 313 Pfam PF03466 LysR substrate binding domain 99 308 3.2E-27 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS00195 d48fc43a06228d005ab8ca57f3acf761 313 Gene3D G3DSA:3.40.190.10 184 280 7.1E-31 T 05-07-2017 K08M4_RS00195 d48fc43a06228d005ab8ca57f3acf761 313 SUPERFAMILY SSF53850 92 307 1.99E-45 T 05-07-2017 K08M4_RS11810 082ddce7fc2567f9431b5f3b7fc33b91 75 SUPERFAMILY SSF161187 3 71 4.32E-24 T 05-07-2017 IPR029037 YfgJ-like K08M4_RS11810 082ddce7fc2567f9431b5f3b7fc33b91 75 ProDom PD060428 YFGJ CYTOPLASMIC VP0614 ECS3372 VC0765 YPO2873 Y1359 STY2763A VV0773 6 69 1.0E-20 T 05-07-2017 IPR010807 Protein of unknown function DUF1407 K08M4_RS11810 082ddce7fc2567f9431b5f3b7fc33b91 75 Gene3D G3DSA:2.10.290.10 3 72 2.3E-27 T 05-07-2017 IPR029037 YfgJ-like K08M4_RS11810 082ddce7fc2567f9431b5f3b7fc33b91 75 Pfam PF07191 zinc-ribbons 5 69 1.4E-25 T 05-07-2017 IPR010807 Protein of unknown function DUF1407 K08M4_RS11205 6dd50a1702ff70d3ad6eb09962cb4bca 250 SUPERFAMILY SSF64005 9 234 2.62E-88 T 05-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 K08M4_RS11205 6dd50a1702ff70d3ad6eb09962cb4bca 250 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 11 239 39.564 T 05-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 K08M4_RS11205 6dd50a1702ff70d3ad6eb09962cb4bca 250 Pfam PF01255 Putative undecaprenyl diphosphate synthase 18 238 6.9E-82 T 05-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 K08M4_RS11205 6dd50a1702ff70d3ad6eb09962cb4bca 250 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 184 201 - T 05-07-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 K08M4_RS11205 6dd50a1702ff70d3ad6eb09962cb4bca 250 Gene3D G3DSA:3.40.1180.10 9 245 1.9E-99 T 05-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 K08M4_RS11205 6dd50a1702ff70d3ad6eb09962cb4bca 250 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 11 238 1.4E-94 T 05-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 K08M4_RS01790 e74db8cc44f3628481712e8f5fcc0ed9 91 PRINTS PR00107 Phosphocarrier protein signature 55 72 2.5E-11 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS01790 e74db8cc44f3628481712e8f5fcc0ed9 91 PRINTS PR00107 Phosphocarrier protein signature 14 30 2.5E-11 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS01790 e74db8cc44f3628481712e8f5fcc0ed9 91 PRINTS PR00107 Phosphocarrier protein signature 40 55 2.5E-11 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS01790 e74db8cc44f3628481712e8f5fcc0ed9 91 SUPERFAMILY SSF55594 4 90 2.88E-25 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS01790 e74db8cc44f3628481712e8f5fcc0ed9 91 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 3 84 1.5E-22 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS01790 e74db8cc44f3628481712e8f5fcc0ed9 91 Pfam PF00381 PTS HPr component phosphorylation site 4 84 1.9E-23 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS01790 e74db8cc44f3628481712e8f5fcc0ed9 91 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 14 21 - T 05-07-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site K08M4_RS01790 e74db8cc44f3628481712e8f5fcc0ed9 91 Gene3D G3DSA:3.30.1340.10 4 89 3.5E-27 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS01790 e74db8cc44f3628481712e8f5fcc0ed9 91 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 41 56 - T 05-07-2017 IPR002114 Phosphotransferase system, HPr serine phosphorylation site K08M4_RS06875 d3f719277e3fbb9a4e5a1c2a67215b3d 301 Gene3D G3DSA:3.40.190.10 202 263 4.2E-9 T 05-07-2017 K08M4_RS06875 d3f719277e3fbb9a4e5a1c2a67215b3d 301 SUPERFAMILY SSF46785 1 108 5.4E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06875 d3f719277e3fbb9a4e5a1c2a67215b3d 301 SUPERFAMILY SSF53850 91 298 4.46E-26 T 05-07-2017 K08M4_RS06875 d3f719277e3fbb9a4e5a1c2a67215b3d 301 Gene3D G3DSA:3.40.190.10 80 201 8.5E-13 T 05-07-2017 K08M4_RS06875 d3f719277e3fbb9a4e5a1c2a67215b3d 301 Pfam PF03466 LysR substrate binding domain 91 293 7.4E-25 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS06875 d3f719277e3fbb9a4e5a1c2a67215b3d 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 8.7E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS06875 d3f719277e3fbb9a4e5a1c2a67215b3d 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 8.7E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS06875 d3f719277e3fbb9a4e5a1c2a67215b3d 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 8.7E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS06875 d3f719277e3fbb9a4e5a1c2a67215b3d 301 Gene3D G3DSA:1.10.10.10 1 79 1.2E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06875 d3f719277e3fbb9a4e5a1c2a67215b3d 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.8E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS14665 07945fa15293b575898414354c607e94 83 Pfam PF04380 Membrane fusogenic activity 1 78 8.8E-28 T 05-07-2017 IPR007475 Membrane fusogenic activity K08M4_RS17380 ec97ca0d9ff0c3e5a3b29c591c7617fa 261 Gene3D G3DSA:3.40.50.300 3 230 8.3E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17380 ec97ca0d9ff0c3e5a3b29c591c7617fa 261 SMART SM00382 26 214 2.4E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS17380 ec97ca0d9ff0c3e5a3b29c591c7617fa 261 SUPERFAMILY SSF52540 3 229 2.11E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17380 ec97ca0d9ff0c3e5a3b29c591c7617fa 261 Pfam PF00005 ABC transporter 21 166 8.3E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS17380 ec97ca0d9ff0c3e5a3b29c591c7617fa 261 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS20230 d3419ba93822e6e4f6cdf3b3c8671b87 268 Gene3D G3DSA:1.10.10.60 165 201 9.9E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20230 d3419ba93822e6e4f6cdf3b3c8671b87 268 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 245 261 1.2E-6 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS20230 d3419ba93822e6e4f6cdf3b3c8671b87 268 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 230 245 1.2E-6 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS20230 d3419ba93822e6e4f6cdf3b3c8671b87 268 Pfam PF12833 Helix-turn-helix domain 185 261 8.1E-20 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS20230 d3419ba93822e6e4f6cdf3b3c8671b87 268 SMART SM00342 179 261 1.9E-26 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS20230 d3419ba93822e6e4f6cdf3b3c8671b87 268 SUPERFAMILY SSF46689 215 262 8.66E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20230 d3419ba93822e6e4f6cdf3b3c8671b87 268 Gene3D G3DSA:1.10.10.60 215 262 4.8E-18 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20230 d3419ba93822e6e4f6cdf3b3c8671b87 268 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 212 257 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 K08M4_RS01075 b37feade78452c9221b650cf70fc1959 302 Gene3D G3DSA:3.30.70.1350 207 288 8.9E-30 T 05-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain K08M4_RS01075 b37feade78452c9221b650cf70fc1959 302 Pfam PF01545 Cation efflux family 14 206 7.3E-45 T 05-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 K08M4_RS01075 b37feade78452c9221b650cf70fc1959 302 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 287 4.5E-69 T 05-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 K08M4_RS01075 b37feade78452c9221b650cf70fc1959 302 SUPERFAMILY SSF160240 210 288 2.62E-24 T 05-07-2017 K08M4_RS01075 b37feade78452c9221b650cf70fc1959 302 Pfam PF16916 Dimerisation domain of Zinc Transporter 210 287 1.8E-26 T 05-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain K08M4_RS01075 b37feade78452c9221b650cf70fc1959 302 Gene3D G3DSA:1.20.1510.10 12 206 4.5E-43 T 05-07-2017 IPR027469 Cation efflux protein transmembrane domain K08M4_RS01075 b37feade78452c9221b650cf70fc1959 302 SUPERFAMILY SSF161111 8 207 4.84E-51 T 05-07-2017 K08M4_RS14640 945add9a2b8100b234884d6ab2be0c78 137 Gene3D G3DSA:1.10.760.10 58 134 1.4E-32 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS14640 945add9a2b8100b234884d6ab2be0c78 137 PRINTS PR00607 Class IE cytochrome C signature 69 80 1.7E-16 T 05-07-2017 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 K08M4_RS14640 945add9a2b8100b234884d6ab2be0c78 137 PRINTS PR00607 Class IE cytochrome C signature 123 134 1.7E-16 T 05-07-2017 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 K08M4_RS14640 945add9a2b8100b234884d6ab2be0c78 137 PRINTS PR00607 Class IE cytochrome C signature 108 120 1.7E-16 T 05-07-2017 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 K08M4_RS14640 945add9a2b8100b234884d6ab2be0c78 137 PRINTS PR00607 Class IE cytochrome C signature 80 90 1.7E-16 T 05-07-2017 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 K08M4_RS14640 945add9a2b8100b234884d6ab2be0c78 137 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 59 133 6.9E-16 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS14640 945add9a2b8100b234884d6ab2be0c78 137 SUPERFAMILY SSF46626 60 133 1.47E-18 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 Gene3D G3DSA:1.10.220.30 215 350 8.8E-42 T 05-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 Pfam PF14842 FliG N-terminal domain 25 125 8.5E-27 T 05-07-2017 IPR028263 Flagellar motor switch protein FliG, N-terminal domain K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 SUPERFAMILY SSF48029 134 345 5.49E-67 T 05-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 Gene3D G3DSA:1.10.220.30 29 94 2.2E-13 T 05-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 Gene3D G3DSA:1.10.220.30 125 209 2.5E-31 T 05-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 PIRSF PIRSF003161 19 352 3.0E-113 T 05-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 SUPERFAMILY SSF48029 27 136 4.18E-19 T 05-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 20 350 6.6E-96 T 05-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 Pfam PF14841 FliG middle domain 135 207 4.0E-26 T 05-07-2017 IPR032779 Flagellar motor switch protein FliG, middle domain K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 Pfam PF01706 FliG C-terminal domain 238 344 8.9E-41 T 05-07-2017 IPR023087 Flagellar motor switch protein FliG, C-terminal K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 PRINTS PR00954 Flagellar motor switch protein FliG signature 292 318 3.4E-55 T 05-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 PRINTS PR00954 Flagellar motor switch protein FliG signature 25 41 3.4E-55 T 05-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 PRINTS PR00954 Flagellar motor switch protein FliG signature 215 240 3.4E-55 T 05-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 PRINTS PR00954 Flagellar motor switch protein FliG signature 54 80 3.4E-55 T 05-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 PRINTS PR00954 Flagellar motor switch protein FliG signature 246 266 3.4E-55 T 05-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 PRINTS PR00954 Flagellar motor switch protein FliG signature 268 288 3.4E-55 T 05-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 K08M4_RS04160 207355fafe87278efbf1020e643a2eb8 352 PRINTS PR00954 Flagellar motor switch protein FliG signature 134 157 3.4E-55 T 05-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 K08M4_RS09880 d7a15923d4f02ea3341e911bbb57b186 463 Gene3D G3DSA:1.25.40.10 133 160 7.9E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS09880 d7a15923d4f02ea3341e911bbb57b186 463 Gene3D G3DSA:1.25.40.10 204 256 7.9E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS09880 d7a15923d4f02ea3341e911bbb57b186 463 SUPERFAMILY SSF48452 204 255 9.11E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS09880 d7a15923d4f02ea3341e911bbb57b186 463 SUPERFAMILY SSF48452 67 160 9.11E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS10330 ad9423df925b0978000b6b9cfffd4a3f 435 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 85 424 1.3E-105 T 05-07-2017 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 K08M4_RS10330 ad9423df925b0978000b6b9cfffd4a3f 435 Gene3D G3DSA:3.60.120.10 15 426 3.7E-91 T 05-07-2017 IPR005801 ADC synthase GO:0009058 K08M4_RS10330 ad9423df925b0978000b6b9cfffd4a3f 435 Pfam PF00425 chorismate binding enzyme 164 417 2.2E-74 T 05-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal K08M4_RS10330 ad9423df925b0978000b6b9cfffd4a3f 435 SUPERFAMILY SSF56322 25 425 6.8E-104 T 05-07-2017 IPR005801 ADC synthase GO:0009058 K08M4_RS10330 ad9423df925b0978000b6b9cfffd4a3f 435 Hamap MF_01935 Isochorismate synthase MenF [menF]. 4 427 37.672 T 05-07-2017 K08M4_RS04910 a269424154b44d8304ab44bb0998d062 295 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 9 270 4.1E-103 T 05-07-2017 IPR010119 Gluconeogenesis factor K08M4_RS04910 a269424154b44d8304ab44bb0998d062 295 Pfam PF01933 Uncharacterised protein family UPF0052 9 257 5.9E-75 T 05-07-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 K08M4_RS04910 a269424154b44d8304ab44bb0998d062 295 Hamap MF_00973 Gluconeogenesis factor. 5 295 29.746 T 05-07-2017 IPR010119 Gluconeogenesis factor K08M4_RS04910 a269424154b44d8304ab44bb0998d062 295 SUPERFAMILY SSF142338 7 291 8.5E-84 T 05-07-2017 K08M4_RS04910 a269424154b44d8304ab44bb0998d062 295 Gene3D G3DSA:3.40.50.10680 79 293 7.7E-54 T 05-07-2017 K08M4_RS19815 765120c30ab00b90dd1be5d65b85e5a9 83 Pfam PF11212 Protein of unknown function (DUF2999) 1 82 2.5E-46 T 05-07-2017 IPR021376 Protein of unknown function DUF2999 K08M4_RS05885 8ebe19f353b30302d8907ee774e830af 335 SUPERFAMILY SSF53850 27 332 2.71E-90 T 05-07-2017 K08M4_RS05885 8ebe19f353b30302d8907ee774e830af 335 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 35 317 1.4E-51 T 05-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 K08M4_RS05885 8ebe19f353b30302d8907ee774e830af 335 Gene3D G3DSA:3.40.190.10 268 334 6.9E-54 T 05-07-2017 K08M4_RS05885 8ebe19f353b30302d8907ee774e830af 335 Gene3D G3DSA:3.40.190.10 28 116 6.9E-54 T 05-07-2017 K08M4_RS05885 8ebe19f353b30302d8907ee774e830af 335 Gene3D G3DSA:3.40.190.100 117 267 2.6E-52 T 05-07-2017 K08M4_RS15780 05f46cfe709aa02f2ebb6e44fb5fc570 82 SUPERFAMILY SSF143120 6 61 6.28E-9 T 05-07-2017 K08M4_RS09710 d1c7c12c3a89f9ca0c96ec03935c6ea9 435 PIRSF PIRSF001529 1 435 5.2E-184 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 K08M4_RS09710 d1c7c12c3a89f9ca0c96ec03935c6ea9 435 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 433 40.722 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 K08M4_RS09710 d1c7c12c3a89f9ca0c96ec03935c6ea9 435 Gene3D G3DSA:1.10.287.40 1 106 7.4E-25 T 05-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 K08M4_RS09710 d1c7c12c3a89f9ca0c96ec03935c6ea9 435 Gene3D G3DSA:3.30.930.10 107 431 4.8E-139 T 05-07-2017 K08M4_RS09710 d1c7c12c3a89f9ca0c96ec03935c6ea9 435 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 1.7E-29 T 05-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 K08M4_RS09710 d1c7c12c3a89f9ca0c96ec03935c6ea9 435 SUPERFAMILY SSF46589 1 114 6.28E-28 T 05-07-2017 IPR010978 tRNA-binding arm GO:0000166 K08M4_RS09710 d1c7c12c3a89f9ca0c96ec03935c6ea9 435 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 236 411 6.1E-33 T 05-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS09710 d1c7c12c3a89f9ca0c96ec03935c6ea9 435 SUPERFAMILY SSF55681 118 433 1.71E-99 T 05-07-2017 K08M4_RS09710 d1c7c12c3a89f9ca0c96ec03935c6ea9 435 PRINTS PR00981 Seryl-tRNA synthetase signature 327 340 2.1E-33 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 K08M4_RS09710 d1c7c12c3a89f9ca0c96ec03935c6ea9 435 PRINTS PR00981 Seryl-tRNA synthetase signature 344 360 2.1E-33 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 K08M4_RS09710 d1c7c12c3a89f9ca0c96ec03935c6ea9 435 PRINTS PR00981 Seryl-tRNA synthetase signature 275 287 2.1E-33 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 K08M4_RS09710 d1c7c12c3a89f9ca0c96ec03935c6ea9 435 PRINTS PR00981 Seryl-tRNA synthetase signature 287 300 2.1E-33 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 K08M4_RS09710 d1c7c12c3a89f9ca0c96ec03935c6ea9 435 PRINTS PR00981 Seryl-tRNA synthetase signature 362 378 2.1E-33 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 K08M4_RS09710 d1c7c12c3a89f9ca0c96ec03935c6ea9 435 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 428 5.8E-172 T 05-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 K08M4_RS05275 bceb27bcc82821d9a85a1167f6dcde74 256 Gene3D G3DSA:3.40.190.10 6 135 2.4E-45 T 05-07-2017 K08M4_RS05275 bceb27bcc82821d9a85a1167f6dcde74 256 SMART SM00062 26 252 1.1E-66 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS05275 bceb27bcc82821d9a85a1167f6dcde74 256 SMART SM00079 26 251 1.9E-4 T 05-07-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 K08M4_RS05275 bceb27bcc82821d9a85a1167f6dcde74 256 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 27 250 3.0E-61 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS05275 bceb27bcc82821d9a85a1167f6dcde74 256 SUPERFAMILY SSF53850 1 253 5.08E-70 T 05-07-2017 K08M4_RS05275 bceb27bcc82821d9a85a1167f6dcde74 256 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 6 249 2.9E-81 T 05-07-2017 IPR005768 Lysine-arginine-ornithine-binding periplasmic protein GO:0005215|GO:0006810|GO:0030288 K08M4_RS05275 bceb27bcc82821d9a85a1167f6dcde74 256 Gene3D G3DSA:3.40.190.10 136 209 4.3E-24 T 05-07-2017 K08M4_RS12900 9d1627b185ab6c949bb17f5416856ce0 174 SMART SM00014 61 170 1.1E-8 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase K08M4_RS12900 9d1627b185ab6c949bb17f5416856ce0 174 Pfam PF01569 PAP2 superfamily 65 170 7.1E-18 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase K08M4_RS12900 9d1627b185ab6c949bb17f5416856ce0 174 SUPERFAMILY SSF48317 7 171 3.79E-34 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase K08M4_RS12900 9d1627b185ab6c949bb17f5416856ce0 174 Gene3D G3DSA:1.20.144.10 6 170 1.0E-36 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase K08M4_RS03575 970b3d5845a6cdd5319c5000a70c98c0 363 Pfam PF01728 FtsJ-like methyltransferase 188 251 4.3E-5 T 05-07-2017 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 K08M4_RS03575 970b3d5845a6cdd5319c5000a70c98c0 363 SUPERFAMILY SSF53335 186 281 2.78E-12 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS03575 970b3d5845a6cdd5319c5000a70c98c0 363 Gene3D G3DSA:3.40.50.150 186 281 1.1E-11 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS03575 970b3d5845a6cdd5319c5000a70c98c0 363 Hamap MF_01551 Ribosomal RNA large subunit methyltransferase M [rlmM]. 1 357 83.098 T 05-07-2017 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 K08M4_RS03575 970b3d5845a6cdd5319c5000a70c98c0 363 PIRSF PIRSF028774 1 362 4.3E-187 T 05-07-2017 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 K08M4_RS17495 a01432e0fc59ef06a6fe8bfb77a0c734 138 Gene3D G3DSA:2.60.40.10 24 123 3.5E-5 T 05-07-2017 IPR013783 Immunoglobulin-like fold K08M4_RS17495 a01432e0fc59ef06a6fe8bfb77a0c734 138 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 43 138 4.5E-15 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS17495 a01432e0fc59ef06a6fe8bfb77a0c734 138 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 2 37 5.3E-7 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS14400 f30764be60b54463e956bfa56facdbb3 84 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 48 1.3E-21 T 05-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 K08M4_RS14400 f30764be60b54463e956bfa56facdbb3 84 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 79 25.615 T 05-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 K08M4_RS14400 f30764be60b54463e956bfa56facdbb3 84 Pfam PF02416 mttA/Hcf106 family 4 55 5.4E-14 T 05-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 K08M4_RS20445 22bd9d2d99f2a0a73719bee96317d201 145 SUPERFAMILY SSF53927 2 139 8.7E-40 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 K08M4_RS20445 22bd9d2d99f2a0a73719bee96317d201 145 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 103 4.7E-19 T 05-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 K08M4_RS20445 22bd9d2d99f2a0a73719bee96317d201 145 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 49 91 - T 05-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 K08M4_RS20445 22bd9d2d99f2a0a73719bee96317d201 145 Gene3D G3DSA:3.40.140.10 2 139 2.1E-31 T 05-07-2017 K08M4_RS12380 d09c3e0566eac0cfcaa3b581175372a4 62 Pfam PF12065 Protein of unknown function (DUF3545) 1 61 1.2E-24 T 05-07-2017 IPR021932 Protein of unknown function DUF3545 K08M4_RS13965 af910f273c46a52c8e253ec577e74620 366 Gene3D G3DSA:3.40.50.2000 168 359 1.0E-43 T 05-07-2017 K08M4_RS13965 af910f273c46a52c8e253ec577e74620 366 SUPERFAMILY SSF53756 8 359 5.81E-62 T 05-07-2017 K08M4_RS13965 af910f273c46a52c8e253ec577e74620 366 Gene3D G3DSA:3.40.50.2000 8 149 1.3E-20 T 05-07-2017 K08M4_RS13965 af910f273c46a52c8e253ec577e74620 366 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 166 290 3.7E-23 T 05-07-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 K08M4_RS07300 47f74ddbcc6338ccabc8499ae77e7f29 377 SUPERFAMILY SSF111369 67 269 1.57E-22 T 05-07-2017 K08M4_RS07300 47f74ddbcc6338ccabc8499ae77e7f29 377 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 55 368 7.5E-61 T 05-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 K08M4_RS07300 47f74ddbcc6338ccabc8499ae77e7f29 377 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 73 248 4.4E-13 T 05-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain K08M4_RS07300 47f74ddbcc6338ccabc8499ae77e7f29 377 Gene3D G3DSA:2.40.50.100 186 217 8.6E-16 T 05-07-2017 K08M4_RS07300 47f74ddbcc6338ccabc8499ae77e7f29 377 Gene3D G3DSA:2.40.50.100 79 111 8.6E-16 T 05-07-2017 K08M4_RS07485 605c707425369086a1cae0b6b0a1c435 487 Pfam PF00158 Sigma-54 interaction domain 161 326 3.6E-68 T 05-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 K08M4_RS07485 605c707425369086a1cae0b6b0a1c435 487 SMART SM00448 22 133 4.6E-27 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS07485 605c707425369086a1cae0b6b0a1c435 487 SUPERFAMILY SSF52540 160 390 2.04E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07485 605c707425369086a1cae0b6b0a1c435 487 Gene3D G3DSA:3.40.50.2300 23 144 1.4E-28 T 05-07-2017 K08M4_RS07485 605c707425369086a1cae0b6b0a1c435 487 SUPERFAMILY SSF46689 430 479 4.93E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS07485 605c707425369086a1cae0b6b0a1c435 487 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 246 261 - T 05-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 K08M4_RS07485 605c707425369086a1cae0b6b0a1c435 487 SMART SM00382 181 324 6.1E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS07485 605c707425369086a1cae0b6b0a1c435 487 Gene3D G3DSA:3.40.50.300 159 332 2.0E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07485 605c707425369086a1cae0b6b0a1c435 487 Pfam PF02954 Bacterial regulatory protein, Fis family 437 476 1.7E-7 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS07485 605c707425369086a1cae0b6b0a1c435 487 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 185 198 - T 05-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 K08M4_RS07485 605c707425369086a1cae0b6b0a1c435 487 Gene3D G3DSA:1.10.10.60 428 479 6.3E-18 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS07485 605c707425369086a1cae0b6b0a1c435 487 Gene3D G3DSA:1.10.8.60 333 392 5.2E-15 T 05-07-2017 K08M4_RS07485 605c707425369086a1cae0b6b0a1c435 487 SUPERFAMILY SSF52172 22 205 6.69E-35 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS07485 605c707425369086a1cae0b6b0a1c435 487 Pfam PF00072 Response regulator receiver domain 24 133 1.9E-22 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS07485 605c707425369086a1cae0b6b0a1c435 487 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 373 382 - T 05-07-2017 IPR025944 Sigma-54 interaction domain, conserved site K08M4_RS06965 8d9660d45bd822cf36842acff9384bf8 140 SUPERFAMILY SSF52402 3 139 4.69E-22 T 05-07-2017 K08M4_RS06965 8d9660d45bd822cf36842acff9384bf8 140 Pfam PF00582 Universal stress protein family 3 138 2.6E-11 T 05-07-2017 IPR006016 UspA GO:0006950 K08M4_RS06965 8d9660d45bd822cf36842acff9384bf8 140 Gene3D G3DSA:3.40.50.620 3 138 6.6E-17 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS06965 8d9660d45bd822cf36842acff9384bf8 140 PIRSF PIRSF006276 1 140 1.4E-38 T 05-07-2017 IPR006015 Universal stress protein A K08M4_RS12710 14aef5fc25ea41b21ff85a6f35b61e64 201 Pfam PF05728 Uncharacterised protein family (UPF0227) 14 199 2.1E-71 T 05-07-2017 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA K08M4_RS12710 14aef5fc25ea41b21ff85a6f35b61e64 201 SUPERFAMILY SSF53474 6 200 1.33E-22 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS12710 14aef5fc25ea41b21ff85a6f35b61e64 201 Gene3D G3DSA:3.40.50.1820 10 195 2.0E-18 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS18575 fb6acf9a5a797ded83adef2754b0fd3c 893 Pfam PF13380 CoA binding domain 11 137 1.8E-23 T 05-07-2017 IPR003781 CoA-binding GO:0048037 K08M4_RS18575 fb6acf9a5a797ded83adef2754b0fd3c 893 SUPERFAMILY SSF56059 493 704 1.38E-29 T 05-07-2017 K08M4_RS18575 fb6acf9a5a797ded83adef2754b0fd3c 893 Pfam PF13302 Acetyltransferase (GNAT) domain 738 876 1.4E-8 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS18575 fb6acf9a5a797ded83adef2754b0fd3c 893 SUPERFAMILY SSF51735 2 141 1.07E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS18575 fb6acf9a5a797ded83adef2754b0fd3c 893 SUPERFAMILY SSF55729 735 878 4.87E-18 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS18575 fb6acf9a5a797ded83adef2754b0fd3c 893 Gene3D G3DSA:3.40.50.720 2 133 2.8E-32 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS18575 fb6acf9a5a797ded83adef2754b0fd3c 893 Gene3D G3DSA:3.40.50.261 287 449 8.6E-20 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 K08M4_RS18575 fb6acf9a5a797ded83adef2754b0fd3c 893 Pfam PF13549 ATP-grasp domain 486 706 3.4E-69 T 05-07-2017 K08M4_RS18575 fb6acf9a5a797ded83adef2754b0fd3c 893 Gene3D G3DSA:3.40.50.261 134 286 7.2E-24 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 K08M4_RS18575 fb6acf9a5a797ded83adef2754b0fd3c 893 SUPERFAMILY SSF52210 297 457 4.71E-41 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 K08M4_RS18575 fb6acf9a5a797ded83adef2754b0fd3c 893 SUPERFAMILY SSF52210 133 291 8.5E-38 T 05-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 K08M4_RS18575 fb6acf9a5a797ded83adef2754b0fd3c 893 Gene3D G3DSA:3.30.470.20 499 606 5.8E-5 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS18575 fb6acf9a5a797ded83adef2754b0fd3c 893 Gene3D G3DSA:3.40.630.30 732 891 2.2E-17 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS18575 fb6acf9a5a797ded83adef2754b0fd3c 893 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 153 290 6.1E-50 T 05-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain K08M4_RS18575 fb6acf9a5a797ded83adef2754b0fd3c 893 SMART SM00881 7 102 2.9E-24 T 05-07-2017 IPR003781 CoA-binding GO:0048037 K08M4_RS14555 bdeb200f4200000ccba997276c6ebeb9 680 Pfam PF01432 Peptidase family M3 222 677 3.6E-163 T 05-07-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 K08M4_RS14555 bdeb200f4200000ccba997276c6ebeb9 680 Gene3D G3DSA:3.40.390.10 361 504 5.0E-59 T 05-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 K08M4_RS14555 bdeb200f4200000ccba997276c6ebeb9 680 SUPERFAMILY SSF55486 1 677 5.37E-211 T 05-07-2017 K08M4_RS14555 bdeb200f4200000ccba997276c6ebeb9 680 Gene3D G3DSA:1.20.1050.40 9 138 9.5E-27 T 05-07-2017 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal K08M4_RS14555 bdeb200f4200000ccba997276c6ebeb9 680 Gene3D G3DSA:1.10.1370.10 140 349 1.5E-141 T 05-07-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 K08M4_RS14555 bdeb200f4200000ccba997276c6ebeb9 680 Gene3D G3DSA:1.10.1370.10 505 679 1.5E-141 T 05-07-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 K08M4_RS05805 50a27072cd5da9e1886b72433de665d1 216 SUPERFAMILY SSF52540 4 201 1.54E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05805 50a27072cd5da9e1886b72433de665d1 216 Gene3D G3DSA:3.40.50.300 3 199 1.9E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05805 50a27072cd5da9e1886b72433de665d1 216 Pfam PF00005 ABC transporter 21 163 2.6E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS05805 50a27072cd5da9e1886b72433de665d1 216 SMART SM00382 28 212 2.9E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 Gene3D G3DSA:1.10.10.60 459 513 7.0E-26 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 Gene3D G3DSA:1.10.8.60 377 450 9.7E-19 T 05-07-2017 K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 290 305 - T 05-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 SMART SM00382 225 368 4.0E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 Gene3D G3DSA:3.30.450.20 79 169 5.0E-10 T 05-07-2017 K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 SMART SM00091 80 146 3.2E-7 T 05-07-2017 IPR000014 PAS domain K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 SUPERFAMILY SSF55785 82 159 4.71E-10 T 05-07-2017 IPR000014 PAS domain K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 Gene3D G3DSA:3.30.70.260 1 68 3.3E-6 T 05-07-2017 K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 229 242 - T 05-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 Pfam PF00158 Sigma-54 interaction domain 206 370 1.9E-55 T 05-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 465 513 1.4E-28 T 05-07-2017 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 SUPERFAMILY SSF52540 205 445 8.42E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 417 426 - T 05-07-2017 IPR025944 Sigma-54 interaction domain, conserved site K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 Gene3D G3DSA:3.40.50.300 202 376 7.5E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 SUPERFAMILY SSF46689 458 512 2.99E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 Pfam PF00989 PAS fold 84 130 4.3E-6 T 05-07-2017 IPR013767 PAS fold GO:0006355 K08M4_RS08445 b6e9da95ff35832a70b035c9232af1a7 514 SUPERFAMILY SSF55021 1 68 4.51E-6 T 05-07-2017 K08M4_RS03445 3c1095cb09a9f5128a6a5a86a6fa38f8 348 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 50 317 3.0E-66 T 05-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 K08M4_RS03445 3c1095cb09a9f5128a6a5a86a6fa38f8 348 Gene3D G3DSA:3.40.630.10 30 232 1.1E-26 T 05-07-2017 K08M4_RS03445 3c1095cb09a9f5128a6a5a86a6fa38f8 348 SUPERFAMILY SSF53187 22 319 4.3E-76 T 05-07-2017 K08M4_RS03445 3c1095cb09a9f5128a6a5a86a6fa38f8 348 PIRSF PIRSF039012 6 325 1.7E-93 T 05-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 SUPERFAMILY SSF143517 995 1146 2.22E-42 T 05-07-2017 K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 28 1110 28.689 T 05-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 Pfam PF00270 DEAD/DEAH box helicase 605 765 6.8E-21 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 SUPERFAMILY SSF141259 470 548 1.31E-24 T 05-07-2017 IPR003711 CarD-like/TRCF domain K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 148 1081 0.0 T 05-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 SUPERFAMILY SSF52540 351 466 1.7E-28 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 Pfam PF00271 Helicase conserved C-terminal domain 807 909 2.4E-16 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 SMART SM00490 826 910 2.5E-17 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 Pfam PF02559 CarD-like/TRCF domain 480 575 8.3E-25 T 05-07-2017 IPR003711 CarD-like/TRCF domain K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 Gene3D G3DSA:3.40.50.300 593 786 2.6E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 Pfam PF03461 TRCF domain 1010 1101 6.4E-27 T 05-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 SUPERFAMILY SSF52540 11 342 1.5E-101 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 SMART SM01058 479 576 1.3E-50 T 05-07-2017 IPR003711 CarD-like/TRCF domain K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 SUPERFAMILY SSF52540 782 990 1.11E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 Gene3D G3DSA:3.40.50.300 787 963 9.2E-36 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 SUPERFAMILY SSF52540 524 783 4.38E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 SMART SM00487 600 790 9.7E-33 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 SMART SM00982 1008 1108 1.7E-44 T 05-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 K08M4_RS09840 cf7ba6e966436e6e90cb9541d59a6a13 1153 Gene3D G3DSA:3.30.2060.10 132 207 8.0E-15 T 05-07-2017 K08M4_RS00250 91e21d201ba2b7ca9bf10e162f0beabb 264 SUPERFAMILY SSF51215 23 139 8.5E-19 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 K08M4_RS00250 91e21d201ba2b7ca9bf10e162f0beabb 264 Gene3D G3DSA:2.60.120.280 17 98 1.7E-14 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 K08M4_RS00250 91e21d201ba2b7ca9bf10e162f0beabb 264 SUPERFAMILY SSF46689 166 215 3.84E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00250 91e21d201ba2b7ca9bf10e162f0beabb 264 SMART SM00342 182 264 2.5E-21 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS00250 91e21d201ba2b7ca9bf10e162f0beabb 264 Pfam PF02311 AraC-like ligand binding domain 13 137 5.9E-21 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 K08M4_RS00250 91e21d201ba2b7ca9bf10e162f0beabb 264 SUPERFAMILY SSF46689 219 263 1.16E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00250 91e21d201ba2b7ca9bf10e162f0beabb 264 Gene3D G3DSA:1.10.10.60 220 263 4.5E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00250 91e21d201ba2b7ca9bf10e162f0beabb 264 Pfam PF12833 Helix-turn-helix domain 190 262 3.5E-19 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS00250 91e21d201ba2b7ca9bf10e162f0beabb 264 Gene3D G3DSA:1.10.10.60 165 219 3.8E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS14265 6fffaabce45e05f6db38f2e96091774f 541 PIRSF PIRSF006294 4 540 2.0E-225 T 05-07-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 K08M4_RS14265 6fffaabce45e05f6db38f2e96091774f 541 Hamap MF_00453 Phosphoenolpyruvate carboxykinase [ATP] [pckA]. 18 538 54.594 T 05-07-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 K08M4_RS14265 6fffaabce45e05f6db38f2e96091774f 541 Pfam PF01293 Phosphoenolpyruvate carboxykinase 24 490 1.9E-209 T 05-07-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 K08M4_RS14265 6fffaabce45e05f6db38f2e96091774f 541 SUPERFAMILY SSF53795 229 540 3.2E-126 T 05-07-2017 K08M4_RS14265 6fffaabce45e05f6db38f2e96091774f 541 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 10 540 1.4E-276 T 05-07-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 K08M4_RS14265 6fffaabce45e05f6db38f2e96091774f 541 Gene3D G3DSA:3.40.449.10 24 227 5.1E-87 T 05-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 K08M4_RS14265 6fffaabce45e05f6db38f2e96091774f 541 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 265 280 - T 05-07-2017 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 K08M4_RS14265 6fffaabce45e05f6db38f2e96091774f 541 SUPERFAMILY SSF68923 11 227 5.58E-88 T 05-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 K08M4_RS14265 6fffaabce45e05f6db38f2e96091774f 541 Gene3D G3DSA:3.90.228.20 351 539 3.7E-118 T 05-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 K08M4_RS14265 6fffaabce45e05f6db38f2e96091774f 541 Gene3D G3DSA:3.90.228.20 228 290 3.7E-118 T 05-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 K08M4_RS14390 cd188a9d0b5fc6e88874fe5301ed5c8e 251 ProSitePatterns PS01218 TatC family signature. 155 174 - T 05-07-2017 IPR019820 Sec-independent periplasmic protein translocase, conserved site K08M4_RS14390 cd188a9d0b5fc6e88874fe5301ed5c8e 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 104 130 1.4E-51 T 05-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 K08M4_RS14390 cd188a9d0b5fc6e88874fe5301ed5c8e 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 86 104 1.4E-51 T 05-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 K08M4_RS14390 cd188a9d0b5fc6e88874fe5301ed5c8e 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 9 36 1.4E-51 T 05-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 K08M4_RS14390 cd188a9d0b5fc6e88874fe5301ed5c8e 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 155 183 1.4E-51 T 05-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 K08M4_RS14390 cd188a9d0b5fc6e88874fe5301ed5c8e 251 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 4 241 18.273 T 05-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 K08M4_RS14390 cd188a9d0b5fc6e88874fe5301ed5c8e 251 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 10 227 1.5E-75 T 05-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 K08M4_RS14390 cd188a9d0b5fc6e88874fe5301ed5c8e 251 Pfam PF00902 Sec-independent protein translocase protein (TatC) 13 222 1.2E-65 T 05-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 K08M4_RS21710 7a56f5e67fa303b0cb8a3f25800ad81d 288 SUPERFAMILY SSF52172 9 149 3.42E-31 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS21710 7a56f5e67fa303b0cb8a3f25800ad81d 288 SMART SM00448 10 122 1.7E-26 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS21710 7a56f5e67fa303b0cb8a3f25800ad81d 288 SMART SM00850 189 288 1.3E-17 T 05-07-2017 IPR007492 LytTR DNA-binding domain GO:0003677 K08M4_RS21710 7a56f5e67fa303b0cb8a3f25800ad81d 288 Gene3D G3DSA:2.40.50.40 182 252 5.8E-15 T 05-07-2017 K08M4_RS21710 7a56f5e67fa303b0cb8a3f25800ad81d 288 Gene3D G3DSA:3.40.50.2300 10 133 2.8E-32 T 05-07-2017 K08M4_RS21710 7a56f5e67fa303b0cb8a3f25800ad81d 288 Pfam PF00072 Response regulator receiver domain 13 121 9.6E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS21710 7a56f5e67fa303b0cb8a3f25800ad81d 288 Pfam PF04397 LytTr DNA-binding domain 190 287 4.7E-21 T 05-07-2017 IPR007492 LytTR DNA-binding domain GO:0003677 K08M4_RS10920 8cba8450e8ea3955c4e588ab4b8de24d 388 Pfam PF07196 Flagellin hook IN motif 194 249 5.3E-12 T 05-07-2017 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 K08M4_RS10920 8cba8450e8ea3955c4e588ab4b8de24d 388 SUPERFAMILY SSF64518 1 387 3.79E-99 T 05-07-2017 K08M4_RS10920 8cba8450e8ea3955c4e588ab4b8de24d 388 PRINTS PR00207 Flagellin signature 37 54 3.5E-27 T 05-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 K08M4_RS10920 8cba8450e8ea3955c4e588ab4b8de24d 388 PRINTS PR00207 Flagellin signature 76 95 3.5E-27 T 05-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 K08M4_RS10920 8cba8450e8ea3955c4e588ab4b8de24d 388 PRINTS PR00207 Flagellin signature 111 134 3.5E-27 T 05-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 K08M4_RS10920 8cba8450e8ea3955c4e588ab4b8de24d 388 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 9.5E-42 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS10920 8cba8450e8ea3955c4e588ab4b8de24d 388 Pfam PF00700 Bacterial flagellin C-terminal helical region 303 387 4.4E-27 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS10920 8cba8450e8ea3955c4e588ab4b8de24d 388 Gene3D G3DSA:1.20.1330.10 290 343 3.5E-62 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS10920 8cba8450e8ea3955c4e588ab4b8de24d 388 Gene3D G3DSA:1.20.1330.10 55 171 3.5E-62 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS12675 16f6883bfa2f0cff9a3e4c530cf16019 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.797 T 05-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 K08M4_RS12675 16f6883bfa2f0cff9a3e4c530cf16019 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 6.4E-65 T 05-07-2017 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS12675 16f6883bfa2f0cff9a3e4c530cf16019 142 Gene3D G3DSA:3.90.1180.10 3 141 2.7E-65 T 05-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 K08M4_RS12675 16f6883bfa2f0cff9a3e4c530cf16019 142 PIRSF PIRSF002181 1 142 3.8E-53 T 05-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 K08M4_RS12675 16f6883bfa2f0cff9a3e4c530cf16019 142 Pfam PF00572 Ribosomal protein L13 15 138 1.1E-56 T 05-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 K08M4_RS12675 16f6883bfa2f0cff9a3e4c530cf16019 142 SUPERFAMILY SSF52161 1 140 2.35E-60 T 05-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 K08M4_RS12675 16f6883bfa2f0cff9a3e4c530cf16019 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 05-07-2017 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 K08M4_RS20975 fa16587fc60524cf6b6f2c7a86a7aa01 100 Gene3D G3DSA:3.40.50.2300 1 95 1.4E-33 T 05-07-2017 K08M4_RS20975 fa16587fc60524cf6b6f2c7a86a7aa01 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 93 6.4E-13 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS20975 fa16587fc60524cf6b6f2c7a86a7aa01 100 SUPERFAMILY SSF52794 2 94 1.92E-29 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS20975 fa16587fc60524cf6b6f2c7a86a7aa01 100 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 79 1.8E-28 T 05-07-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 K08M4_RS02285 574063ffd30b7d31d8bb05d47b958d78 383 Gene3D G3DSA:3.30.300.10 244 379 9.8E-70 T 05-07-2017 K08M4_RS02285 574063ffd30b7d31d8bb05d47b958d78 383 PIRSF PIRSF000497 1 381 2.2E-173 T 05-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 K08M4_RS02285 574063ffd30b7d31d8bb05d47b958d78 383 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 377 1.4E-194 T 05-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 K08M4_RS02285 574063ffd30b7d31d8bb05d47b958d78 383 SUPERFAMILY SSF55973 3 109 2.86E-47 T 05-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 K08M4_RS02285 574063ffd30b7d31d8bb05d47b958d78 383 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 5.1E-43 T 05-07-2017 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 K08M4_RS02285 574063ffd30b7d31d8bb05d47b958d78 383 SUPERFAMILY SSF55973 233 381 4.71E-70 T 05-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 K08M4_RS02285 574063ffd30b7d31d8bb05d47b958d78 383 SUPERFAMILY SSF55973 111 232 7.46E-50 T 05-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 K08M4_RS02285 574063ffd30b7d31d8bb05d47b958d78 383 Pfam PF02772 S-adenosylmethionine synthetase, central domain 114 231 4.1E-43 T 05-07-2017 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 K08M4_RS02285 574063ffd30b7d31d8bb05d47b958d78 383 Gene3D G3DSA:3.30.300.10 133 233 1.1E-40 T 05-07-2017 K08M4_RS02285 574063ffd30b7d31d8bb05d47b958d78 383 Gene3D G3DSA:3.30.300.10 11 132 2.5E-49 T 05-07-2017 K08M4_RS02285 574063ffd30b7d31d8bb05d47b958d78 383 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 116 126 - T 05-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 K08M4_RS02285 574063ffd30b7d31d8bb05d47b958d78 383 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 259 267 - T 05-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 K08M4_RS02285 574063ffd30b7d31d8bb05d47b958d78 383 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 381 58.17 T 05-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 K08M4_RS02285 574063ffd30b7d31d8bb05d47b958d78 383 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 233 369 2.4E-69 T 05-07-2017 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 K08M4_RS09805 6f908530303672075452ddd8d821cee0 582 SMART SM00382 368 555 4.5E-20 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS09805 6f908530303672075452ddd8d821cee0 582 ProSitePatterns PS00211 ABC transporters family signature. 481 495 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS09805 6f908530303672075452ddd8d821cee0 582 Gene3D G3DSA:1.20.1560.10 13 324 1.3E-73 T 05-07-2017 K08M4_RS09805 6f908530303672075452ddd8d821cee0 582 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 12 581 1.5E-239 T 05-07-2017 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 K08M4_RS09805 6f908530303672075452ddd8d821cee0 582 SUPERFAMILY SSF90123 14 325 1.44E-72 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS09805 6f908530303672075452ddd8d821cee0 582 SUPERFAMILY SSF52540 331 580 3.07E-93 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09805 6f908530303672075452ddd8d821cee0 582 Pfam PF00664 ABC transporter transmembrane region 28 292 1.1E-56 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS09805 6f908530303672075452ddd8d821cee0 582 Pfam PF00005 ABC transporter 359 509 5.3E-36 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS09805 6f908530303672075452ddd8d821cee0 582 Gene3D G3DSA:3.40.50.300 342 574 2.0E-84 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11845 456886b291b78decf8a628e525404e9f 373 PIRSF PIRSF004640 1 364 3.0E-147 T 05-07-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 K08M4_RS11845 456886b291b78decf8a628e525404e9f 373 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 9 352 6.5E-127 T 05-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 K08M4_RS11845 456886b291b78decf8a628e525404e9f 373 SUPERFAMILY SSF51717 15 208 5.65E-11 T 05-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS11845 456886b291b78decf8a628e525404e9f 373 SUPERFAMILY SSF56014 265 354 5.23E-12 T 05-07-2017 K08M4_RS11845 456886b291b78decf8a628e525404e9f 373 Gene3D G3DSA:3.20.20.70 29 132 4.4E-9 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS11845 456886b291b78decf8a628e525404e9f 373 Pfam PF04551 GcpE protein 14 354 1.1E-131 T 05-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 K08M4_RS11845 456886b291b78decf8a628e525404e9f 373 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 7 359 34.969 T 05-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 K08M4_RS02465 d65995729bfe1402960e81bd30579c02 242 SUPERFAMILY SSF50249 6 76 7.2E-15 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS02465 d65995729bfe1402960e81bd30579c02 242 Gene3D G3DSA:2.40.50.140 8 76 2.3E-8 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS02465 d65995729bfe1402960e81bd30579c02 242 TIGRFAM TIGR00613 reco: DNA repair protein RecO 7 229 6.8E-40 T 05-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 K08M4_RS02465 d65995729bfe1402960e81bd30579c02 242 SUPERFAMILY SSF57863 87 165 3.4E-11 T 05-07-2017 K08M4_RS02465 d65995729bfe1402960e81bd30579c02 242 Pfam PF11967 Recombination protein O N terminal 6 77 3.1E-23 T 05-07-2017 IPR022572 DNA replication/recombination mediator RecO, N-terminal K08M4_RS02465 d65995729bfe1402960e81bd30579c02 242 Hamap MF_00201 DNA repair protein RecO [recO]. 2 232 22.313 T 05-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 K08M4_RS02465 d65995729bfe1402960e81bd30579c02 242 Pfam PF02565 Recombination protein O C terminal 85 226 4.0E-22 T 05-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 K08M4_RS03935 35624328e7970a8af22f0cafd2aa9ca0 515 Gene3D G3DSA:1.20.200.10 204 511 8.5E-103 T 05-07-2017 K08M4_RS03935 35624328e7970a8af22f0cafd2aa9ca0 515 SUPERFAMILY SSF48557 6 511 1.65E-172 T 05-07-2017 IPR008948 L-Aspartase-like GO:0003824 K08M4_RS03935 35624328e7970a8af22f0cafd2aa9ca0 515 Gene3D G3DSA:1.10.275.10 4 203 1.2E-62 T 05-07-2017 IPR024083 Fumarase/histidase, N-terminal K08M4_RS03935 35624328e7970a8af22f0cafd2aa9ca0 515 Pfam PF00221 Aromatic amino acid lyase 16 475 6.1E-162 T 05-07-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 K08M4_RS03935 35624328e7970a8af22f0cafd2aa9ca0 515 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 145 161 - T 05-07-2017 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 K08M4_RS10310 fbb9f3959a9c49dec1bf96d76a42816d 335 TIGRFAM TIGR01927 menC_gamma/gm+: o-succinylbenzoate synthase 13 318 2.7E-105 T 05-07-2017 K08M4_RS10310 fbb9f3959a9c49dec1bf96d76a42816d 335 SUPERFAMILY SSF54826 8 106 4.32E-24 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS10310 fbb9f3959a9c49dec1bf96d76a42816d 335 SMART SM00922 123 220 2.4E-6 T 05-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal K08M4_RS10310 fbb9f3959a9c49dec1bf96d76a42816d 335 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 10 327 24.246 T 05-07-2017 IPR010196 o-succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS10310 fbb9f3959a9c49dec1bf96d76a42816d 335 Gene3D G3DSA:3.30.390.10 8 130 4.3E-30 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS10310 fbb9f3959a9c49dec1bf96d76a42816d 335 Pfam PF13378 Enolase C-terminal domain-like 132 288 1.6E-12 T 05-07-2017 IPR029065 Enolase C-terminal domain-like K08M4_RS10310 fbb9f3959a9c49dec1bf96d76a42816d 335 Gene3D G3DSA:3.20.20.120 131 311 2.8E-44 T 05-07-2017 IPR029065 Enolase C-terminal domain-like K08M4_RS10310 fbb9f3959a9c49dec1bf96d76a42816d 335 SUPERFAMILY SSF51604 111 317 6.42E-45 T 05-07-2017 IPR029065 Enolase C-terminal domain-like K08M4_RS16630 87779057681a953292b11b4e9ab8afd0 553 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 1 551 1.7E-225 T 05-07-2017 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 K08M4_RS16630 87779057681a953292b11b4e9ab8afd0 553 PIRSF PIRSF000076 1 553 1.3E-236 T 05-07-2017 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 K08M4_RS16630 87779057681a953292b11b4e9ab8afd0 553 Gene3D G3DSA:1.20.1270.20 141 161 4.6E-35 T 05-07-2017 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 K08M4_RS16630 87779057681a953292b11b4e9ab8afd0 553 Gene3D G3DSA:1.20.1270.20 1 109 4.6E-35 T 05-07-2017 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 K08M4_RS16630 87779057681a953292b11b4e9ab8afd0 553 Gene3D G3DSA:3.40.50.2030 383 550 6.6E-69 T 05-07-2017 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 K08M4_RS16630 87779057681a953292b11b4e9ab8afd0 553 Gene3D G3DSA:1.20.1270.20 162 235 2.1E-24 T 05-07-2017 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 K08M4_RS16630 87779057681a953292b11b4e9ab8afd0 553 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 552 20.103 T 05-07-2017 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 K08M4_RS16630 87779057681a953292b11b4e9ab8afd0 553 SUPERFAMILY SSF56821 1 551 1.02E-190 T 05-07-2017 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 K08M4_RS16630 87779057681a953292b11b4e9ab8afd0 553 Gene3D G3DSA:3.40.50.2030 237 382 2.7E-66 T 05-07-2017 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 K08M4_RS16630 87779057681a953292b11b4e9ab8afd0 553 Pfam PF03063 Prismane/CO dehydrogenase family 1 548 2.8E-161 T 05-07-2017 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 28 337 2.1E-124 T 05-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 550 53.588 T 05-07-2017 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 SUPERFAMILY SSF52374 11 337 7.19E-100 T 05-07-2017 K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 60 73 6.0E-10 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 45 56 6.0E-10 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 31 43 6.0E-10 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 220 6.0E-10 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 Gene3D G3DSA:3.90.800.10 101 209 3.2E-46 T 05-07-2017 K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 340 529 1.9E-62 T 05-07-2017 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 SUPERFAMILY SSF50715 340 548 3.56E-80 T 05-07-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 Gene3D G3DSA:1.10.1160.10 263 338 2.6E-37 T 05-07-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 34 45 - T 05-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 Gene3D G3DSA:2.40.240.10 463 548 6.0E-33 T 05-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 Gene3D G3DSA:3.40.50.620 28 96 8.6E-44 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 Gene3D G3DSA:3.40.50.620 212 262 8.6E-44 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 28 552 1.4E-294 T 05-07-2017 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 K08M4_RS10645 35ff2bd166d92da2f573fe2acdeea43a 555 Gene3D G3DSA:2.40.240.10 348 462 2.1E-50 T 05-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 K08M4_RS09300 ec6a3b6506c3bd90c91b45922f7af7bc 394 Gene3D G3DSA:3.40.640.10 6 255 9.9E-82 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS09300 ec6a3b6506c3bd90c91b45922f7af7bc 394 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 7 389 2.8E-174 T 05-07-2017 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 K08M4_RS09300 ec6a3b6506c3bd90c91b45922f7af7bc 394 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 387 3.7E-117 T 05-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 K08M4_RS09300 ec6a3b6506c3bd90c91b45922f7af7bc 394 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 199 213 - T 05-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 K08M4_RS09300 ec6a3b6506c3bd90c91b45922f7af7bc 394 SUPERFAMILY SSF53383 23 388 7.31E-100 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS09300 ec6a3b6506c3bd90c91b45922f7af7bc 394 PIRSF PIRSF001434 1 391 1.5E-125 T 05-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 K08M4_RS09300 ec6a3b6506c3bd90c91b45922f7af7bc 394 Gene3D G3DSA:3.90.1150.10 256 389 3.8E-37 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS21370 ccb25b92b487cf78d5932c4548b0fcba 112 Pfam PF08895 Domain of unknown function (DUF1840) 1 104 1.8E-32 T 05-07-2017 IPR014991 Protein of unknown function DUF1840 K08M4_RS15745 5f25c8dbca6621462ec7960b35c67d68 467 Pfam PF02264 LamB porin 55 467 8.5E-37 T 05-07-2017 IPR003192 Porin, LamB type GO:0006810|GO:0016020 K08M4_RS15745 5f25c8dbca6621462ec7960b35c67d68 467 ProDom PD008788 PORIN MEMBRANE PRECURSOR SIGNAL MALTOPORIN OUTER ION TRANSMEMBRANE RECEPTOR LAMB 114 461 3.0E-135 T 05-07-2017 IPR003192 Porin, LamB type GO:0006810|GO:0016020 K08M4_RS15745 5f25c8dbca6621462ec7960b35c67d68 467 Gene3D G3DSA:2.40.170.10 50 467 1.4E-86 T 05-07-2017 IPR003192 Porin, LamB type GO:0006810|GO:0016020 K08M4_RS15745 5f25c8dbca6621462ec7960b35c67d68 467 SUPERFAMILY SSF56935 52 467 5.04E-78 T 05-07-2017 K08M4_RS10245 120be42833ad06661c0b8c27515fa193 363 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 38 343 2.5E-84 T 05-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 K08M4_RS10245 120be42833ad06661c0b8c27515fa193 363 Gene3D G3DSA:2.40.50.100 63 96 6.2E-16 T 05-07-2017 K08M4_RS10245 120be42833ad06661c0b8c27515fa193 363 Gene3D G3DSA:2.40.50.100 157 188 6.2E-16 T 05-07-2017 K08M4_RS10245 120be42833ad06661c0b8c27515fa193 363 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 48 263 7.3E-31 T 05-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain K08M4_RS10245 120be42833ad06661c0b8c27515fa193 363 SUPERFAMILY SSF111369 52 267 1.83E-39 T 05-07-2017 K08M4_RS15895 a671e390a30f52eee0ec72fc3a44b339 564 Pfam PF12558 ATP-binding cassette cobalt transporter 234 306 3.8E-20 T 05-07-2017 IPR022216 ABC cobalt transporter GO:0016820 K08M4_RS15895 a671e390a30f52eee0ec72fc3a44b339 564 SUPERFAMILY SSF52540 3 234 3.1E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15895 a671e390a30f52eee0ec72fc3a44b339 564 SMART SM00382 324 510 3.1E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS15895 a671e390a30f52eee0ec72fc3a44b339 564 SMART SM00382 29 221 3.4E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS15895 a671e390a30f52eee0ec72fc3a44b339 564 Pfam PF00005 ABC transporter 315 461 5.5E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS15895 a671e390a30f52eee0ec72fc3a44b339 564 Pfam PF00005 ABC transporter 20 170 1.1E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS15895 a671e390a30f52eee0ec72fc3a44b339 564 Gene3D G3DSA:3.40.50.300 3 236 4.2E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15895 a671e390a30f52eee0ec72fc3a44b339 564 SUPERFAMILY SSF52540 285 530 6.29E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15895 a671e390a30f52eee0ec72fc3a44b339 564 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS15895 a671e390a30f52eee0ec72fc3a44b339 564 ProSitePatterns PS00211 ABC transporters family signature. 433 447 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS15895 a671e390a30f52eee0ec72fc3a44b339 564 Gene3D G3DSA:3.40.50.300 291 530 2.2E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05360 4471ba2dc22efe1eac607d6c47400a4d 76 Pfam PF00313 'Cold-shock' DNA-binding domain 6 69 8.1E-28 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS05360 4471ba2dc22efe1eac607d6c47400a4d 76 PRINTS PR00050 Cold shock protein signature 28 37 8.6E-15 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS05360 4471ba2dc22efe1eac607d6c47400a4d 76 PRINTS PR00050 Cold shock protein signature 43 61 8.6E-15 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS05360 4471ba2dc22efe1eac607d6c47400a4d 76 PRINTS PR00050 Cold shock protein signature 7 22 8.6E-15 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS05360 4471ba2dc22efe1eac607d6c47400a4d 76 TIGRFAM TIGR02381 cspD: cold shock domain protein CspD 4 71 2.4E-41 T 05-07-2017 IPR012751 CspD, cold shock GO:0003676|GO:0005737|GO:0006355|GO:0006950 K08M4_RS05360 4471ba2dc22efe1eac607d6c47400a4d 76 SMART SM00357 6 70 3.1E-25 T 05-07-2017 IPR011129 Cold shock protein GO:0003676 K08M4_RS05360 4471ba2dc22efe1eac607d6c47400a4d 76 Gene3D G3DSA:2.40.50.140 4 68 2.6E-29 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS05360 4471ba2dc22efe1eac607d6c47400a4d 76 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 05-07-2017 IPR019844 Cold-shock conserved site K08M4_RS05360 4471ba2dc22efe1eac607d6c47400a4d 76 SUPERFAMILY SSF50249 2 70 4.93E-23 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS05360 4471ba2dc22efe1eac607d6c47400a4d 76 PIRSF PIRSF002599 1 76 1.3E-23 T 05-07-2017 IPR012156 Cold shock, CspA GO:0003676 K08M4_RS12610 82dd40f557b0d61fd8d3d2462eebf94e 316 SUPERFAMILY SSF53335 7 113 4.68E-43 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS12610 82dd40f557b0d61fd8d3d2462eebf94e 316 SUPERFAMILY SSF53335 217 316 4.68E-43 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS12610 82dd40f557b0d61fd8d3d2462eebf94e 316 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 315 5.6E-117 T 05-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS12610 82dd40f557b0d61fd8d3d2462eebf94e 316 Pfam PF01795 MraW methylase family 5 315 1.0E-107 T 05-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS12610 82dd40f557b0d61fd8d3d2462eebf94e 316 Gene3D G3DSA:1.10.150.170 112 219 8.4E-33 T 05-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS12610 82dd40f557b0d61fd8d3d2462eebf94e 316 Gene3D G3DSA:3.40.50.150 7 110 2.5E-47 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS12610 82dd40f557b0d61fd8d3d2462eebf94e 316 Gene3D G3DSA:3.40.50.150 220 316 2.5E-47 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS12610 82dd40f557b0d61fd8d3d2462eebf94e 316 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 316 37.051 T 05-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS12610 82dd40f557b0d61fd8d3d2462eebf94e 316 SUPERFAMILY SSF81799 113 216 3.14E-29 T 05-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS12610 82dd40f557b0d61fd8d3d2462eebf94e 316 PIRSF PIRSF004486 1 316 7.6E-99 T 05-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS03415 dab84173bd25efeafad4d6b92e4a425d 239 Gene3D G3DSA:3.40.50.150 25 168 1.6E-27 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS03415 dab84173bd25efeafad4d6b92e4a425d 239 SUPERFAMILY SSF53335 53 193 7.54E-28 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS03415 dab84173bd25efeafad4d6b92e4a425d 239 Pfam PF08241 Methyltransferase domain 57 153 3.6E-18 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 K08M4_RS09060 014d8efc91212ba170fbe5edba8bb722 324 Gene3D G3DSA:1.20.1630.10 14 204 4.8E-6 T 05-07-2017 K08M4_RS09060 014d8efc91212ba170fbe5edba8bb722 324 Pfam PF03916 Polysulphide reductase, NrfD 7 324 1.1E-78 T 05-07-2017 IPR005614 NrfD family K08M4_RS09060 014d8efc91212ba170fbe5edba8bb722 324 TIGRFAM TIGR03148 cyt_nit_nrfD: cytochrome c nitrite reductase, NrfD subunit 7 324 2.3E-142 T 05-07-2017 IPR017566 NrfD K08M4_RS05130 a68f9b85c75fb2dbc034766e5390da05 414 SUPERFAMILY SSF53901 215 413 2.46E-67 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS05130 a68f9b85c75fb2dbc034766e5390da05 414 SUPERFAMILY SSF53901 4 252 1.48E-78 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS05130 a68f9b85c75fb2dbc034766e5390da05 414 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 370 4.5E-36 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal K08M4_RS05130 a68f9b85c75fb2dbc034766e5390da05 414 Gene3D G3DSA:3.40.47.10 3 257 6.4E-78 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS05130 a68f9b85c75fb2dbc034766e5390da05 414 SMART SM00825 Beta-ketoacyl synthase 6 414 2.3E-15 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain K08M4_RS05130 a68f9b85c75fb2dbc034766e5390da05 414 Gene3D G3DSA:3.40.47.10 263 413 5.8E-58 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS05130 a68f9b85c75fb2dbc034766e5390da05 414 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site K08M4_RS05130 a68f9b85c75fb2dbc034766e5390da05 414 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 412 1.6E-188 T 05-07-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 K08M4_RS05130 a68f9b85c75fb2dbc034766e5390da05 414 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 247 5.0E-64 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal K08M4_RS05130 a68f9b85c75fb2dbc034766e5390da05 414 PIRSF PIRSF000447 1 414 5.3E-199 T 05-07-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 K08M4_RS09760 cb6cc6314c1710ac664c0b2fa8be60ee 231 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 3 231 40.021 T 05-07-2017 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS09760 cb6cc6314c1710ac664c0b2fa8be60ee 231 SMART SM00934 5 226 2.7E-102 T 05-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS09760 cb6cc6314c1710ac664c0b2fa8be60ee 231 Gene3D G3DSA:3.20.20.70 2 227 9.8E-91 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS09760 cb6cc6314c1710ac664c0b2fa8be60ee 231 SUPERFAMILY SSF51366 3 227 7.95E-77 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 K08M4_RS09760 cb6cc6314c1710ac664c0b2fa8be60ee 231 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 5 225 4.0E-54 T 05-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS09760 cb6cc6314c1710ac664c0b2fa8be60ee 231 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 7 226 1.4E-58 T 05-07-2017 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS09760 cb6cc6314c1710ac664c0b2fa8be60ee 231 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 57 70 - T 05-07-2017 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS19535 b9b9b046b7b7fc826e4567cccd42421f 596 SMART SM00332 12 254 9.9E-16 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 K08M4_RS19535 b9b9b046b7b7fc826e4567cccd42421f 596 Gene3D G3DSA:1.10.510.10 399 539 7.4E-30 T 05-07-2017 K08M4_RS19535 b9b9b046b7b7fc826e4567cccd42421f 596 SUPERFAMILY SSF56112 286 572 1.48E-50 T 05-07-2017 IPR011009 Protein kinase-like domain K08M4_RS19535 b9b9b046b7b7fc826e4567cccd42421f 596 Pfam PF00069 Protein kinase domain 292 539 1.1E-37 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 K08M4_RS19535 b9b9b046b7b7fc826e4567cccd42421f 596 SMART SM00331 36 256 1.0E-5 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 K08M4_RS19535 b9b9b046b7b7fc826e4567cccd42421f 596 Pfam PF13672 Protein phosphatase 2C 33 223 7.6E-15 T 05-07-2017 K08M4_RS19535 b9b9b046b7b7fc826e4567cccd42421f 596 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 408 420 - T 05-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 K08M4_RS19535 b9b9b046b7b7fc826e4567cccd42421f 596 Gene3D G3DSA:3.60.40.10 18 256 5.2E-48 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 K08M4_RS19535 b9b9b046b7b7fc826e4567cccd42421f 596 Gene3D G3DSA:3.30.200.20 262 398 2.9E-16 T 05-07-2017 K08M4_RS19535 b9b9b046b7b7fc826e4567cccd42421f 596 SUPERFAMILY SSF81606 20 256 5.62E-49 T 05-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 K08M4_RS19535 b9b9b046b7b7fc826e4567cccd42421f 596 SMART SM00220 289 550 1.4E-16 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 K08M4_RS01550 e640e4c04a5d6c718e9fbd60ec79e222 166 Gene3D G3DSA:3.30.230.10 76 158 4.4E-32 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup K08M4_RS01550 e640e4c04a5d6c718e9fbd60ec79e222 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 162 1.4E-68 T 05-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 K08M4_RS01550 e640e4c04a5d6c718e9fbd60ec79e222 166 SUPERFAMILY SSF54768 8 75 3.14E-24 T 05-07-2017 K08M4_RS01550 e640e4c04a5d6c718e9fbd60ec79e222 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 34.636 T 05-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 K08M4_RS01550 e640e4c04a5d6c718e9fbd60ec79e222 166 SUPERFAMILY SSF54211 79 158 1.42E-26 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS01550 e640e4c04a5d6c718e9fbd60ec79e222 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 05-07-2017 IPR018192 Ribosomal protein S5, N-terminal, conserved site K08M4_RS01550 e640e4c04a5d6c718e9fbd60ec79e222 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 74 2.5E-29 T 05-07-2017 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 K08M4_RS01550 e640e4c04a5d6c718e9fbd60ec79e222 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 7.6E-29 T 05-07-2017 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 K08M4_RS01550 e640e4c04a5d6c718e9fbd60ec79e222 166 Gene3D G3DSA:3.30.160.20 9 72 7.7E-31 T 05-07-2017 IPR014720 Double-stranded RNA-binding domain K08M4_RS04480 da4c659ef24bee8b4508a323bae13ee4 167 Pfam PF13673 Acetyltransferase (GNAT) domain 81 160 4.0E-10 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS04480 da4c659ef24bee8b4508a323bae13ee4 167 SUPERFAMILY SSF55729 1 157 2.48E-27 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS04480 da4c659ef24bee8b4508a323bae13ee4 167 Gene3D G3DSA:3.40.630.30 2 157 1.1E-34 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS12525 62ffc63fa8db1dc47ad3584c80a16f22 269 Gene3D G3DSA:3.40.50.720 2 163 4.6E-58 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS12525 62ffc63fa8db1dc47ad3584c80a16f22 269 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 265 35.494 T 05-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS12525 62ffc63fa8db1dc47ad3584c80a16f22 269 SUPERFAMILY SSF51735 2 126 7.14E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS12525 62ffc63fa8db1dc47ad3584c80a16f22 269 SUPERFAMILY SSF51735 236 268 7.14E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS12525 62ffc63fa8db1dc47ad3584c80a16f22 269 SUPERFAMILY SSF55347 127 236 2.01E-37 T 05-07-2017 K08M4_RS12525 62ffc63fa8db1dc47ad3584c80a16f22 269 PIRSF PIRSF000161 1 268 1.2E-88 T 05-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS12525 62ffc63fa8db1dc47ad3584c80a16f22 269 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 2 125 3.0E-40 T 05-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS12525 62ffc63fa8db1dc47ad3584c80a16f22 269 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 2 265 1.0E-98 T 05-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS12525 62ffc63fa8db1dc47ad3584c80a16f22 269 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 128 264 1.5E-43 T 05-07-2017 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS12525 62ffc63fa8db1dc47ad3584c80a16f22 269 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 150 167 - T 05-07-2017 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 K08M4_RS09470 e36f1c011f64b3df66b031d2b9337ee2 257 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 256 1.9E-113 T 05-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 K08M4_RS09470 e36f1c011f64b3df66b031d2b9337ee2 257 SUPERFAMILY SSF51366 1 256 1.02E-73 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 K08M4_RS09470 e36f1c011f64b3df66b031d2b9337ee2 257 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 256 44.371 T 05-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 K08M4_RS09470 e36f1c011f64b3df66b031d2b9337ee2 257 Pfam PF00977 Histidine biosynthesis protein 5 239 2.9E-78 T 05-07-2017 IPR006062 Histidine biosynthesis GO:0000105 K08M4_RS09470 e36f1c011f64b3df66b031d2b9337ee2 257 Gene3D G3DSA:3.20.20.70 4 257 5.2E-88 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS00885 b9b218294f045100ad1616e3a0b59cb8 429 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 05-07-2017 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 K08M4_RS00885 b9b218294f045100ad1616e3a0b59cb8 429 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 102 2.1E-34 T 05-07-2017 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 K08M4_RS00885 b9b218294f045100ad1616e3a0b59cb8 429 Gene3D G3DSA:3.40.50.20 2 95 2.2E-36 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS00885 b9b218294f045100ad1616e3a0b59cb8 429 SUPERFAMILY SSF52440 1 103 5.61E-36 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS00885 b9b218294f045100ad1616e3a0b59cb8 429 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 296 7.7E-82 T 05-07-2017 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 K08M4_RS00885 b9b218294f045100ad1616e3a0b59cb8 429 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 423 2.7E-182 T 05-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 K08M4_RS00885 b9b218294f045100ad1616e3a0b59cb8 429 SMART SM01210 330 423 3.6E-51 T 05-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 K08M4_RS00885 b9b218294f045100ad1616e3a0b59cb8 429 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 423 43.551 T 05-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 K08M4_RS00885 b9b218294f045100ad1616e3a0b59cb8 429 Gene3D G3DSA:3.90.600.10 330 423 1.9E-33 T 05-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 K08M4_RS00885 b9b218294f045100ad1616e3a0b59cb8 429 Gene3D G3DSA:3.30.470.20 191 328 1.2E-63 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS00885 b9b218294f045100ad1616e3a0b59cb8 429 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 332 421 6.5E-29 T 05-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 K08M4_RS00885 b9b218294f045100ad1616e3a0b59cb8 429 SUPERFAMILY SSF51246 329 424 1.73E-31 T 05-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 K08M4_RS00885 b9b218294f045100ad1616e3a0b59cb8 429 SMART SM01209 103 296 6.1E-138 T 05-07-2017 K08M4_RS00885 b9b218294f045100ad1616e3a0b59cb8 429 SUPERFAMILY SSF56059 104 320 3.54E-66 T 05-07-2017 K08M4_RS00885 b9b218294f045100ad1616e3a0b59cb8 429 Gene3D G3DSA:3.30.1490.20 122 190 1.2E-33 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 SUPERFAMILY SSF56655 1 260 1.83E-80 T 05-07-2017 K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 4.9E-55 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 4.9E-55 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 4.9E-55 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 4.9E-55 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 4.9E-55 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 4.9E-55 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 Gene3D G3DSA:3.40.190.80 152 259 8.0E-37 T 05-07-2017 K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 05-07-2017 IPR020583 Inositol monophosphatase, metal-binding site K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 211 225 - T 05-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 1.5E-31 T 05-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 198 210 1.5E-31 T 05-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 104 123 1.5E-31 T 05-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 156 182 1.5E-31 T 05-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 Gene3D G3DSA:3.30.540.10 2 151 1.2E-47 T 05-07-2017 K08M4_RS11915 a904f8fb670ae15994a4a373c85293d2 267 Pfam PF00459 Inositol monophosphatase family 2 260 7.5E-66 T 05-07-2017 IPR000760 Inositol monophosphatase GO:0046854 K08M4_RS06000 4972ca0d76bc06368a91a69f431bb576 366 SMART SM00671 86 121 7.5E-9 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS06000 4972ca0d76bc06368a91a69f431bb576 366 SMART SM00671 50 85 5.7E-7 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS06000 4972ca0d76bc06368a91a69f431bb576 366 Gene3D G3DSA:1.10.287.110 309 362 1.9E-10 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS06000 4972ca0d76bc06368a91a69f431bb576 366 SUPERFAMILY SSF81901 48 176 1.83E-21 T 05-07-2017 K08M4_RS06000 4972ca0d76bc06368a91a69f431bb576 366 Pfam PF08238 Sel1 repeat 87 121 6.7E-8 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS06000 4972ca0d76bc06368a91a69f431bb576 366 Pfam PF08238 Sel1 repeat 50 85 3.9E-6 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS06000 4972ca0d76bc06368a91a69f431bb576 366 SUPERFAMILY SSF46565 310 362 3.4E-10 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS06000 4972ca0d76bc06368a91a69f431bb576 366 Gene3D G3DSA:1.25.40.10 48 167 3.6E-26 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS14650 4e8a5bc6b3f4cacd3142c33faaf96d47 205 SUPERFAMILY SSF46689 18 85 8.48E-19 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS14650 4e8a5bc6b3f4cacd3142c33faaf96d47 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.5E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS14650 4e8a5bc6b3f4cacd3142c33faaf96d47 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.5E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS14650 4e8a5bc6b3f4cacd3142c33faaf96d47 205 Pfam PF16295 Tetracycline repressor, C-terminal all-alpha domain 81 202 1.9E-8 T 05-07-2017 IPR032551 HTH-type transcriptional repressor, C-terminal K08M4_RS14650 4e8a5bc6b3f4cacd3142c33faaf96d47 205 SUPERFAMILY SSF48498 95 203 5.52E-6 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal K08M4_RS14650 4e8a5bc6b3f4cacd3142c33faaf96d47 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 8.9E-19 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS14650 4e8a5bc6b3f4cacd3142c33faaf96d47 205 Gene3D G3DSA:1.10.357.10 20 202 1.8E-32 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS14650 4e8a5bc6b3f4cacd3142c33faaf96d47 205 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 68 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site K08M4_RS04485 d7b955b6bcabaafdbf51f14510ca49ea 361 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 05-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 K08M4_RS04485 d7b955b6bcabaafdbf51f14510ca49ea 361 SUPERFAMILY SSF103263 4 353 8.24E-149 T 05-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 K08M4_RS04485 d7b955b6bcabaafdbf51f14510ca49ea 361 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 05-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 K08M4_RS04485 d7b955b6bcabaafdbf51f14510ca49ea 361 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 37.523 T 05-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 K08M4_RS04485 d7b955b6bcabaafdbf51f14510ca49ea 361 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 1.9E-142 T 05-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 K08M4_RS04485 d7b955b6bcabaafdbf51f14510ca49ea 361 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 05-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 K08M4_RS04485 d7b955b6bcabaafdbf51f14510ca49ea 361 PIRSF PIRSF001456 3 360 2.0E-142 T 05-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 K08M4_RS04485 d7b955b6bcabaafdbf51f14510ca49ea 361 Pfam PF01264 Chorismate synthase 10 345 6.8E-143 T 05-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 K08M4_RS04485 d7b955b6bcabaafdbf51f14510ca49ea 361 Gene3D G3DSA:3.60.150.10 9 351 4.1E-161 T 05-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 K08M4_RS01555 04f55573a4341e6947e225bf71b6e2d8 58 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 1.4E-20 T 05-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain K08M4_RS01555 04f55573a4341e6947e225bf71b6e2d8 58 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 21.605 T 05-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 K08M4_RS01555 04f55573a4341e6947e225bf71b6e2d8 58 PIRSF PIRSF002211 1 58 5.9E-28 T 05-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 K08M4_RS01555 04f55573a4341e6947e225bf71b6e2d8 58 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 1.8E-25 T 05-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 K08M4_RS01555 04f55573a4341e6947e225bf71b6e2d8 58 SUPERFAMILY SSF55129 1 58 6.15E-23 T 05-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain K08M4_RS01555 04f55573a4341e6947e225bf71b6e2d8 58 Gene3D G3DSA:3.30.1390.20 1 58 7.4E-32 T 05-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain K08M4_RS00960 55117ef745eb97a0ddb5b85e43b9215b 461 SUPERFAMILY SSF48557 5 455 6.19E-135 T 05-07-2017 IPR008948 L-Aspartase-like GO:0003824 K08M4_RS00960 55117ef745eb97a0ddb5b85e43b9215b 461 Hamap MF_00743 Fumarate hydratase class II [fumC]. 5 457 74.912 T 05-07-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 K08M4_RS00960 55117ef745eb97a0ddb5b85e43b9215b 461 Gene3D G3DSA:1.20.200.10 134 394 1.0E-82 T 05-07-2017 K08M4_RS00960 55117ef745eb97a0ddb5b85e43b9215b 461 Gene3D G3DSA:1.10.275.10 4 133 2.1E-52 T 05-07-2017 IPR024083 Fumarase/histidase, N-terminal K08M4_RS00960 55117ef745eb97a0ddb5b85e43b9215b 461 Gene3D G3DSA:1.10.40.30 403 460 5.1E-20 T 05-07-2017 K08M4_RS00960 55117ef745eb97a0ddb5b85e43b9215b 461 Pfam PF10415 Fumarase C C-terminus 403 455 1.0E-18 T 05-07-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 K08M4_RS00960 55117ef745eb97a0ddb5b85e43b9215b 461 PRINTS PR00145 Argininosuccinate lyase family signature 170 190 3.9E-6 T 05-07-2017 K08M4_RS00960 55117ef745eb97a0ddb5b85e43b9215b 461 PRINTS PR00145 Argininosuccinate lyase family signature 128 150 3.9E-6 T 05-07-2017 K08M4_RS00960 55117ef745eb97a0ddb5b85e43b9215b 461 PRINTS PR00145 Argininosuccinate lyase family signature 312 328 3.9E-6 T 05-07-2017 K08M4_RS00960 55117ef745eb97a0ddb5b85e43b9215b 461 PRINTS PR00149 Fumarate lyase superfamily signature 129 147 3.7E-31 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS00960 55117ef745eb97a0ddb5b85e43b9215b 461 PRINTS PR00149 Fumarate lyase superfamily signature 266 293 3.7E-31 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS00960 55117ef745eb97a0ddb5b85e43b9215b 461 PRINTS PR00149 Fumarate lyase superfamily signature 175 193 3.7E-31 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS00960 55117ef745eb97a0ddb5b85e43b9215b 461 PRINTS PR00149 Fumarate lyase superfamily signature 312 328 3.7E-31 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS00960 55117ef745eb97a0ddb5b85e43b9215b 461 ProSitePatterns PS00163 Fumarate lyases signature. 312 321 - T 05-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 K08M4_RS00960 55117ef745eb97a0ddb5b85e43b9215b 461 Pfam PF00206 Lyase 13 337 2.2E-91 T 05-07-2017 IPR022761 Fumarate lyase, N-terminal K08M4_RS06050 adf838fdaeb19e1efbb25de4b39e38e6 354 SUPERFAMILY SSF52768 20 352 1.64E-82 T 05-07-2017 K08M4_RS06050 adf838fdaeb19e1efbb25de4b39e38e6 354 PIRSF PIRSF036979 33 354 2.6E-31 T 05-07-2017 IPR006035 Ureohydrolase GO:0046872 K08M4_RS06050 adf838fdaeb19e1efbb25de4b39e38e6 354 PRINTS PR00116 Arginase signature 135 150 3.2E-5 T 05-07-2017 IPR006035 Ureohydrolase GO:0046872 K08M4_RS06050 adf838fdaeb19e1efbb25de4b39e38e6 354 PRINTS PR00116 Arginase signature 274 303 3.2E-5 T 05-07-2017 IPR006035 Ureohydrolase GO:0046872 K08M4_RS06050 adf838fdaeb19e1efbb25de4b39e38e6 354 TIGRFAM TIGR01227 hutG: formimidoylglutamase 21 348 1.7E-104 T 05-07-2017 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 K08M4_RS06050 adf838fdaeb19e1efbb25de4b39e38e6 354 Hamap MF_00737 Formimidoylglutamase [hutG]. 16 349 40.319 T 05-07-2017 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 K08M4_RS06050 adf838fdaeb19e1efbb25de4b39e38e6 354 Gene3D G3DSA:3.40.800.10 15 353 6.4E-110 T 05-07-2017 IPR023696 Ureohydrolase domain K08M4_RS06050 adf838fdaeb19e1efbb25de4b39e38e6 354 Pfam PF00491 Arginase family 56 347 4.9E-61 T 05-07-2017 IPR006035 Ureohydrolase GO:0046872 K08M4_RS06050 adf838fdaeb19e1efbb25de4b39e38e6 354 ProSitePatterns PS01053 Arginase family signature. 277 298 - T 05-07-2017 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 K08M4_RS10520 21cb159886cd70f41266b1442729e7d7 76 SUPERFAMILY SSF46785 1 55 2.29E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS10520 21cb159886cd70f41266b1442729e7d7 76 Pfam PF09012 FeoC like transcriptional regulator 2 53 2.6E-13 T 05-07-2017 IPR015102 Transcriptional regulator HTH-type, FeoC K08M4_RS15210 685a4dd123e7d109983e33f3f5392c3f 323 TIGRFAM TIGR03414 ABC_choline_bnd: choline ABC transporter, periplasmic binding protein 30 317 1.5E-144 T 05-07-2017 IPR017783 ABC transporter, choline, substrate-binding protein GO:0015871|GO:0033265|GO:0042597 K08M4_RS15210 685a4dd123e7d109983e33f3f5392c3f 323 SUPERFAMILY SSF53850 32 306 1.26E-86 T 05-07-2017 K08M4_RS15210 685a4dd123e7d109983e33f3f5392c3f 323 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 37 290 1.0E-59 T 05-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 K08M4_RS15210 685a4dd123e7d109983e33f3f5392c3f 323 Gene3D G3DSA:3.40.190.100 123 224 1.1E-20 T 05-07-2017 K08M4_RS15210 685a4dd123e7d109983e33f3f5392c3f 323 Gene3D G3DSA:3.40.190.10 31 118 1.4E-47 T 05-07-2017 K08M4_RS15210 685a4dd123e7d109983e33f3f5392c3f 323 Gene3D G3DSA:3.40.190.10 234 305 1.4E-47 T 05-07-2017 K08M4_RS18615 62bc2e46f007d4fa809a221b05c3c528 812 Pfam PF02687 FtsX-like permease family 695 802 5.8E-12 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 K08M4_RS07490 55d352db478fb70cc86c9476adb52887 675 Pfam PF00512 His Kinase A (phospho-acceptor) domain 445 510 1.3E-12 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS07490 55d352db478fb70cc86c9476adb52887 675 SUPERFAMILY SSF55874 502 662 3.67E-35 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS07490 55d352db478fb70cc86c9476adb52887 675 SMART SM00388 445 512 2.8E-8 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS07490 55d352db478fb70cc86c9476adb52887 675 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 558 664 4.2E-19 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS07490 55d352db478fb70cc86c9476adb52887 675 Gene3D G3DSA:1.10.287.130 441 498 5.0E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS07490 55d352db478fb70cc86c9476adb52887 675 Pfam PF17202 Single cache domain 3 201 312 7.6E-28 T 05-07-2017 IPR033463 Single cache domain 3 K08M4_RS07490 55d352db478fb70cc86c9476adb52887 675 SUPERFAMILY SSF103190 86 306 5.18E-14 T 05-07-2017 IPR029151 Periplasmic sensor domain-like K08M4_RS07490 55d352db478fb70cc86c9476adb52887 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 615 625 1.3E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS07490 55d352db478fb70cc86c9476adb52887 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 597 611 1.3E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS07490 55d352db478fb70cc86c9476adb52887 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 626 644 1.3E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS07490 55d352db478fb70cc86c9476adb52887 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 650 663 1.3E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS07490 55d352db478fb70cc86c9476adb52887 675 SMART SM00387 555 666 3.5E-28 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS07490 55d352db478fb70cc86c9476adb52887 675 Gene3D G3DSA:3.30.565.10 499 664 2.5E-36 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS07490 55d352db478fb70cc86c9476adb52887 675 SUPERFAMILY SSF47384 439 509 5.89E-11 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS19675 eb7a6b05b20c3ceb3a46a7237322fdbb 341 Pfam PF00072 Response regulator receiver domain 7 117 3.7E-24 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS19675 eb7a6b05b20c3ceb3a46a7237322fdbb 341 Pfam PF01966 HD domain 167 288 4.5E-18 T 05-07-2017 IPR006674 HD domain K08M4_RS19675 eb7a6b05b20c3ceb3a46a7237322fdbb 341 Gene3D G3DSA:3.40.50.2300 3 129 1.5E-37 T 05-07-2017 K08M4_RS19675 eb7a6b05b20c3ceb3a46a7237322fdbb 341 SUPERFAMILY SSF109604 144 326 3.45E-41 T 05-07-2017 K08M4_RS19675 eb7a6b05b20c3ceb3a46a7237322fdbb 341 Gene3D G3DSA:1.10.3210.10 155 324 2.4E-23 T 05-07-2017 IPR006674 HD domain K08M4_RS19675 eb7a6b05b20c3ceb3a46a7237322fdbb 341 SMART SM00471 160 298 8.8E-8 T 05-07-2017 IPR003607 HD/PDEase domain K08M4_RS19675 eb7a6b05b20c3ceb3a46a7237322fdbb 341 SUPERFAMILY SSF52172 3 135 1.99E-35 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS19675 eb7a6b05b20c3ceb3a46a7237322fdbb 341 SMART SM00448 5 118 5.8E-36 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS20930 e4cd268cd512aa9c806332d893f8c785 299 Pfam PF00892 EamA-like transporter family 150 283 2.6E-12 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS20930 e4cd268cd512aa9c806332d893f8c785 299 Pfam PF00892 EamA-like transporter family 9 135 7.0E-11 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS20930 e4cd268cd512aa9c806332d893f8c785 299 SUPERFAMILY SSF103481 185 285 5.1E-12 T 05-07-2017 K08M4_RS20930 e4cd268cd512aa9c806332d893f8c785 299 SUPERFAMILY SSF103481 42 138 6.15E-11 T 05-07-2017 K08M4_RS21555 dc7b9643efa68e7552d5f4d0eabbebec 229 TIGRFAM TIGR02451 anti_sig_ChrR: anti-sigma factor, putative, ChrR family 4 226 5.6E-55 T 05-07-2017 IPR012807 Anti-sigma factor ChrR, putative K08M4_RS21555 dc7b9643efa68e7552d5f4d0eabbebec 229 Gene3D G3DSA:2.60.120.10 121 209 2.4E-16 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS21555 dc7b9643efa68e7552d5f4d0eabbebec 229 SUPERFAMILY SSF51182 119 206 4.82E-16 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS21555 dc7b9643efa68e7552d5f4d0eabbebec 229 Pfam PF12973 ChrR Cupin-like domain 126 204 1.2E-17 T 05-07-2017 IPR025979 ChrR-like cupin domain K08M4_RS20200 842a6f6efd7e5f137b8d8dac3988a662 707 SUPERFAMILY SSF56935 36 707 1.89E-121 T 05-07-2017 K08M4_RS20200 842a6f6efd7e5f137b8d8dac3988a662 707 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 64 707 1.2E-138 T 05-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 K08M4_RS20200 842a6f6efd7e5f137b8d8dac3988a662 707 Gene3D G3DSA:2.170.130.10 35 174 2.3E-33 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS20200 842a6f6efd7e5f137b8d8dac3988a662 707 Pfam PF00593 TonB dependent receptor 464 706 4.2E-29 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS20200 842a6f6efd7e5f137b8d8dac3988a662 707 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 52 - T 05-07-2017 IPR010916 TonB box, conserved site K08M4_RS20200 842a6f6efd7e5f137b8d8dac3988a662 707 Gene3D G3DSA:2.40.170.20 175 707 6.1E-105 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS20200 842a6f6efd7e5f137b8d8dac3988a662 707 Pfam PF07715 TonB-dependent Receptor Plug Domain 62 173 7.7E-23 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS02875 5861b07eb04da8339fb426e8d0b40c5d 264 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 1 262 3.5E-112 T 05-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 K08M4_RS02875 5861b07eb04da8339fb426e8d0b40c5d 264 Pfam PF02548 Ketopantoate hydroxymethyltransferase 3 258 1.1E-106 T 05-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 K08M4_RS02875 5861b07eb04da8339fb426e8d0b40c5d 264 PIRSF PIRSF000388 1 264 3.0E-99 T 05-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 K08M4_RS02875 5861b07eb04da8339fb426e8d0b40c5d 264 SUPERFAMILY SSF51621 3 262 1.7E-103 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS02875 5861b07eb04da8339fb426e8d0b40c5d 264 Gene3D G3DSA:3.20.20.60 1 262 1.5E-109 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS02875 5861b07eb04da8339fb426e8d0b40c5d 264 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 263 40.507 T 05-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 K08M4_RS05720 b32dfdc6ee2cd5e8440c4bdb1f1d5473 782 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 8 775 0.0 T 05-07-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 K08M4_RS05720 b32dfdc6ee2cd5e8440c4bdb1f1d5473 782 SUPERFAMILY SSF51726 5 410 9.16E-104 T 05-07-2017 K08M4_RS05720 b32dfdc6ee2cd5e8440c4bdb1f1d5473 782 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 3 776 35.644 T 05-07-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 K08M4_RS05720 b32dfdc6ee2cd5e8440c4bdb1f1d5473 782 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 449 771 1.6E-148 T 05-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 K08M4_RS05720 b32dfdc6ee2cd5e8440c4bdb1f1d5473 782 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 333 5.3E-117 T 05-07-2017 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 K08M4_RS05720 b32dfdc6ee2cd5e8440c4bdb1f1d5473 782 SUPERFAMILY SSF51726 414 776 2.09E-113 T 05-07-2017 K08M4_RS05720 b32dfdc6ee2cd5e8440c4bdb1f1d5473 782 Gene3D G3DSA:3.20.20.210 410 776 5.3E-128 T 05-07-2017 K08M4_RS05720 b32dfdc6ee2cd5e8440c4bdb1f1d5473 782 PIRSF PIRSF000382 2 781 0.0 T 05-07-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 K08M4_RS05720 b32dfdc6ee2cd5e8440c4bdb1f1d5473 782 Gene3D G3DSA:3.20.20.210 4 403 8.9E-141 T 05-07-2017 K08M4_RS16015 ade5c16017ad0bd1168aea1bb827468e 161 Pfam PF14316 Domain of unknown function (DUF4381) 6 151 8.4E-36 T 05-07-2017 IPR025489 Protein of unknown function (DUF4381 K08M4_RS05785 ab1d753722606679c6cb613f73ce6af2 415 SUPERFAMILY SSF56935 359 414 1.33E-30 T 05-07-2017 K08M4_RS05785 ab1d753722606679c6cb613f73ce6af2 415 SUPERFAMILY SSF56935 50 327 1.33E-30 T 05-07-2017 K08M4_RS05785 ab1d753722606679c6cb613f73ce6af2 415 Gene3D G3DSA:2.40.160.10 51 319 5.3E-29 T 05-07-2017 IPR023614 Porin domain K08M4_RS05785 ab1d753722606679c6cb613f73ce6af2 415 Gene3D G3DSA:2.40.160.10 359 395 5.3E-29 T 05-07-2017 IPR023614 Porin domain K08M4_RS12020 3d7ab5ea8780e0c353fff3e70c2ff9aa 698 Gene3D G3DSA:3.30.870.10 498 681 3.0E-66 T 05-07-2017 K08M4_RS12020 3d7ab5ea8780e0c353fff3e70c2ff9aa 698 SUPERFAMILY SSF56024 498 681 1.35E-64 T 05-07-2017 K08M4_RS12020 3d7ab5ea8780e0c353fff3e70c2ff9aa 698 Pfam PF13089 Polyphosphate kinase N-terminal domain 5 107 3.2E-30 T 05-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 K08M4_RS12020 3d7ab5ea8780e0c353fff3e70c2ff9aa 698 PIRSF PIRSF015589 1 696 1.3E-234 T 05-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 K08M4_RS12020 3d7ab5ea8780e0c353fff3e70c2ff9aa 698 Gene3D G3DSA:3.30.870.10 314 497 2.6E-66 T 05-07-2017 K08M4_RS12020 3d7ab5ea8780e0c353fff3e70c2ff9aa 698 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 5 664 6.6E-246 T 05-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 K08M4_RS12020 3d7ab5ea8780e0c353fff3e70c2ff9aa 698 SUPERFAMILY SSF140356 4 103 9.02E-30 T 05-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 K08M4_RS12020 3d7ab5ea8780e0c353fff3e70c2ff9aa 698 SUPERFAMILY SSF143724 105 310 9.02E-57 T 05-07-2017 K08M4_RS12020 3d7ab5ea8780e0c353fff3e70c2ff9aa 698 Pfam PF02503 Polyphosphate kinase middle domain 116 316 1.2E-42 T 05-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 K08M4_RS12020 3d7ab5ea8780e0c353fff3e70c2ff9aa 698 Hamap MF_00347 Polyphosphate kinase [ppk]. 2 681 29.874 T 05-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 K08M4_RS12020 3d7ab5ea8780e0c353fff3e70c2ff9aa 698 Gene3D G3DSA:3.30.1840.10 105 298 4.0E-50 T 05-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 K08M4_RS12020 3d7ab5ea8780e0c353fff3e70c2ff9aa 698 Pfam PF13090 Polyphosphate kinase C-terminal domain 329 656 1.9E-140 T 05-07-2017 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 K08M4_RS12020 3d7ab5ea8780e0c353fff3e70c2ff9aa 698 SUPERFAMILY SSF56024 313 493 5.02E-51 T 05-07-2017 K08M4_RS12140 9325ff5b94feaa91523f62b301ed2e6c 391 PIRSF PIRSF001500 1 383 7.5E-141 T 05-07-2017 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 K08M4_RS12140 9325ff5b94feaa91523f62b301ed2e6c 391 Pfam PF00800 Prephenate dehydratase 109 290 6.1E-58 T 05-07-2017 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 K08M4_RS12140 9325ff5b94feaa91523f62b301ed2e6c 391 Gene3D G3DSA:3.40.190.10 197 276 1.2E-25 T 05-07-2017 K08M4_RS12140 9325ff5b94feaa91523f62b301ed2e6c 391 Gene3D G3DSA:1.20.59.10 5 109 1.5E-41 T 05-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 K08M4_RS12140 9325ff5b94feaa91523f62b301ed2e6c 391 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 328 335 - T 05-07-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 K08M4_RS12140 9325ff5b94feaa91523f62b301ed2e6c 391 SUPERFAMILY SSF48600 7 95 6.78E-19 T 05-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 K08M4_RS12140 9325ff5b94feaa91523f62b301ed2e6c 391 SUPERFAMILY SSF53850 108 294 3.15E-55 T 05-07-2017 K08M4_RS12140 9325ff5b94feaa91523f62b301ed2e6c 391 TIGRFAM TIGR01797 CM_P_1: chorismate mutase 8 91 5.4E-28 T 05-07-2017 IPR010952 Chorismate mutase, gammaproteobacteria GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 K08M4_RS12140 9325ff5b94feaa91523f62b301ed2e6c 391 Pfam PF01817 Chorismate mutase type II 12 91 3.1E-16 T 05-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 K08M4_RS12140 9325ff5b94feaa91523f62b301ed2e6c 391 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 264 286 - T 05-07-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 K08M4_RS12140 9325ff5b94feaa91523f62b301ed2e6c 391 SUPERFAMILY SSF55021 283 380 8.5E-26 T 05-07-2017 K08M4_RS12140 9325ff5b94feaa91523f62b301ed2e6c 391 Gene3D G3DSA:3.40.190.10 110 196 2.1E-31 T 05-07-2017 K08M4_RS12140 9325ff5b94feaa91523f62b301ed2e6c 391 Gene3D G3DSA:3.30.70.260 298 380 1.3E-27 T 05-07-2017 K08M4_RS12140 9325ff5b94feaa91523f62b301ed2e6c 391 SMART SM00830 12 93 2.9E-21 T 05-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 K08M4_RS17745 f18e5c36feee6eaeb0991236542dfbc5 428 SUPERFAMILY SSF52540 21 98 3.54E-6 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17745 f18e5c36feee6eaeb0991236542dfbc5 428 SMART SM00487 20 229 1.6E-54 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS17745 f18e5c36feee6eaeb0991236542dfbc5 428 Pfam PF00271 Helicase conserved C-terminal domain 231 339 4.3E-28 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS17745 f18e5c36feee6eaeb0991236542dfbc5 428 SMART SM00490 258 339 9.3E-31 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS17745 f18e5c36feee6eaeb0991236542dfbc5 428 Gene3D G3DSA:3.40.50.300 1 211 3.7E-75 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17745 f18e5c36feee6eaeb0991236542dfbc5 428 SUPERFAMILY SSF52540 76 356 7.71E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17745 f18e5c36feee6eaeb0991236542dfbc5 428 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 153 161 - T 05-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site K08M4_RS17745 f18e5c36feee6eaeb0991236542dfbc5 428 Gene3D G3DSA:3.40.50.300 212 371 1.0E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17745 f18e5c36feee6eaeb0991236542dfbc5 428 Pfam PF00270 DEAD/DEAH box helicase 25 194 1.8E-50 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS14930 beb3e2d5de2b823702a12175a3ab7814 156 SUPERFAMILY SSF81573 63 121 1.57E-14 T 05-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain K08M4_RS14930 beb3e2d5de2b823702a12175a3ab7814 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 156 5.0E-56 T 05-07-2017 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 K08M4_RS14930 beb3e2d5de2b823702a12175a3ab7814 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 156 12.755 T 05-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 K08M4_RS14930 beb3e2d5de2b823702a12175a3ab7814 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 137 4.8E-35 T 05-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 K08M4_RS14930 beb3e2d5de2b823702a12175a3ab7814 156 Gene3D G3DSA:1.20.5.620 63 122 3.4E-23 T 05-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain K08M4_RS15405 fbeb28e628fd643604c2a1f50969951e 299 Pfam PF02574 Homocysteine S-methyltransferase 6 292 4.8E-49 T 05-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 K08M4_RS15405 fbeb28e628fd643604c2a1f50969951e 299 SUPERFAMILY SSF82282 2 297 3.53E-74 T 05-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 K08M4_RS15405 fbeb28e628fd643604c2a1f50969951e 299 PIRSF PIRSF037505 3 296 1.8E-13 T 05-07-2017 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 K08M4_RS15405 fbeb28e628fd643604c2a1f50969951e 299 Gene3D G3DSA:3.20.20.330 4 296 2.0E-68 T 05-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 K08M4_RS14085 288f22f916a27ef2696cf689f9c4ea89 317 Hamap MF_00492 Transaldolase [tal]. 1 317 51.016 T 05-07-2017 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 K08M4_RS14085 288f22f916a27ef2696cf689f9c4ea89 317 ProSitePatterns PS01054 Transaldolase signature 1. 30 38 - T 05-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 K08M4_RS14085 288f22f916a27ef2696cf689f9c4ea89 317 TIGRFAM TIGR00874 talAB: transaldolase 2 317 4.9E-156 T 05-07-2017 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 K08M4_RS14085 288f22f916a27ef2696cf689f9c4ea89 317 ProSitePatterns PS00958 Transaldolase active site. 128 145 - T 05-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 K08M4_RS14085 288f22f916a27ef2696cf689f9c4ea89 317 Pfam PF00923 Transaldolase 13 313 1.4E-98 T 05-07-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 K08M4_RS14085 288f22f916a27ef2696cf689f9c4ea89 317 SUPERFAMILY SSF51569 1 316 2.2E-112 T 05-07-2017 K08M4_RS14085 288f22f916a27ef2696cf689f9c4ea89 317 Gene3D G3DSA:3.20.20.70 1 316 6.0E-130 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS10595 6e6149773d01e0a2bb00afefcbc798be 429 Gene3D G3DSA:1.10.580.10 52 280 7.7E-99 T 05-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 K08M4_RS10595 6e6149773d01e0a2bb00afefcbc798be 429 Pfam PF00285 Citrate synthase, C-terminal domain 49 411 5.4E-135 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS10595 6e6149773d01e0a2bb00afefcbc798be 429 PRINTS PR00143 Citrate synthase signature 241 269 2.6E-55 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS10595 6e6149773d01e0a2bb00afefcbc798be 429 PRINTS PR00143 Citrate synthase signature 296 316 2.6E-55 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS10595 6e6149773d01e0a2bb00afefcbc798be 429 PRINTS PR00143 Citrate synthase signature 219 234 2.6E-55 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS10595 6e6149773d01e0a2bb00afefcbc798be 429 PRINTS PR00143 Citrate synthase signature 165 178 2.6E-55 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS10595 6e6149773d01e0a2bb00afefcbc798be 429 PRINTS PR00143 Citrate synthase signature 359 375 2.6E-55 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS10595 6e6149773d01e0a2bb00afefcbc798be 429 PRINTS PR00143 Citrate synthase signature 379 393 2.6E-55 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS10595 6e6149773d01e0a2bb00afefcbc798be 429 ProSitePatterns PS00480 Citrate synthase signature. 303 315 - T 05-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 K08M4_RS10595 6e6149773d01e0a2bb00afefcbc798be 429 Gene3D G3DSA:1.10.230.10 281 373 8.1E-44 T 05-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 K08M4_RS10595 6e6149773d01e0a2bb00afefcbc798be 429 SUPERFAMILY SSF48256 4 428 1.2E-167 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS10595 6e6149773d01e0a2bb00afefcbc798be 429 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 15 422 1.8E-237 T 05-07-2017 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 K08M4_RS10595 6e6149773d01e0a2bb00afefcbc798be 429 PIRSF PIRSF001369 38 429 2.2E-173 T 05-07-2017 IPR024176 Citrate synthase, bacterial-type K08M4_RS13990 c46ce35eae4219a92854ba1ee743201a 351 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 69 325 8.1E-70 T 05-07-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 K08M4_RS13990 c46ce35eae4219a92854ba1ee743201a 351 SUPERFAMILY SSF53756 1 343 1.48E-96 T 05-07-2017 K08M4_RS13990 c46ce35eae4219a92854ba1ee743201a 351 TIGRFAM TIGR02195 heptsyl_trn_II: lipopolysaccharide heptosyltransferase II 2 343 2.1E-145 T 05-07-2017 IPR011910 Lipopolysaccharide heptosyltransferase II GO:0009103|GO:0016757 K08M4_RS13990 c46ce35eae4219a92854ba1ee743201a 351 Gene3D G3DSA:3.40.50.2000 1 140 1.7E-51 T 05-07-2017 K08M4_RS13990 c46ce35eae4219a92854ba1ee743201a 351 Gene3D G3DSA:3.40.50.2000 167 342 1.4E-58 T 05-07-2017 K08M4_RS00990 549c2732fbee17868c3d3b636da85338 627 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 235 435 2.6E-19 T 05-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 K08M4_RS00990 549c2732fbee17868c3d3b636da85338 627 SUPERFAMILY SSF74863 35 148 5.23E-40 T 05-07-2017 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain K08M4_RS00990 549c2732fbee17868c3d3b636da85338 627 Pfam PF13899 Thioredoxin-like 523 594 2.5E-10 T 05-07-2017 K08M4_RS00990 549c2732fbee17868c3d3b636da85338 627 ProSitePatterns PS00194 Thioredoxin family active site. 534 552 - T 05-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 K08M4_RS00990 549c2732fbee17868c3d3b636da85338 627 Gene3D G3DSA:3.40.30.10 513 623 4.8E-35 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS00990 549c2732fbee17868c3d3b636da85338 627 SUPERFAMILY SSF52833 514 623 8.09E-21 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS00990 549c2732fbee17868c3d3b636da85338 627 Pfam PF11412 Disulphide bond corrector protein DsbC 38 148 1.2E-29 T 05-07-2017 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain K08M4_RS00990 549c2732fbee17868c3d3b636da85338 627 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 1 626 38.182 T 05-07-2017 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 K08M4_RS00990 549c2732fbee17868c3d3b636da85338 627 Gene3D G3DSA:2.60.40.1250 34 149 2.7E-41 T 05-07-2017 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 2.6E-24 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 2.6E-24 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 2.6E-24 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.6E-24 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.6E-24 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 PRINTS PR00702 Acriflavin resistance protein family signature 332 355 2.6E-24 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 SUPERFAMILY SSF82866 791 1013 1.57E-43 T 05-07-2017 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 SUPERFAMILY SSF82866 296 491 5.75E-38 T 05-07-2017 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 Gene3D G3DSA:3.30.2090.10 712 787 7.8E-7 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 Gene3D G3DSA:3.30.2090.10 184 266 3.5E-16 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 SUPERFAMILY SSF82693 136 182 3.61E-21 T 05-07-2017 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 SUPERFAMILY SSF82693 270 325 3.61E-21 T 05-07-2017 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 SUPERFAMILY SSF82693 555 620 3.14E-5 T 05-07-2017 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 SUPERFAMILY SSF82693 41 135 1.13E-18 T 05-07-2017 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 Gene3D G3DSA:3.30.70.1430 40 140 1.4E-23 T 05-07-2017 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 Pfam PF00873 AcrB/AcrD/AcrF family 3 1009 5.3E-176 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 Gene3D G3DSA:1.10.3850.10 798 1011 6.6E-54 T 05-07-2017 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 Gene3D G3DSA:1.20.1640.10 291 501 1.9E-46 T 05-07-2017 K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 SUPERFAMILY SSF82714 710 786 4.84E-10 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS18860 c687c26f2880463568f6e55f5eee6472 1019 SUPERFAMILY SSF82714 184 266 1.07E-13 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS20125 9383c3e44e422dee0c3005070be2c821 334 SMART SM00448 3 115 1.7E-20 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS20125 9383c3e44e422dee0c3005070be2c821 334 SUPERFAMILY SSF52172 4 123 9.68E-28 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS20125 9383c3e44e422dee0c3005070be2c821 334 SUPERFAMILY SSF103039 140 329 4.05E-38 T 05-07-2017 IPR028976 CheC-like domain K08M4_RS20125 9383c3e44e422dee0c3005070be2c821 334 Pfam PF00072 Response regulator receiver domain 5 114 1.5E-22 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS20125 9383c3e44e422dee0c3005070be2c821 334 Gene3D G3DSA:3.40.1550.10 140 330 4.9E-37 T 05-07-2017 IPR028976 CheC-like domain K08M4_RS20125 9383c3e44e422dee0c3005070be2c821 334 Gene3D G3DSA:3.40.50.2300 4 123 6.5E-28 T 05-07-2017 K08M4_RS08735 32e4725115f1aa47af125caafb639bfe 405 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 22 400 5.9E-117 T 05-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 K08M4_RS08735 32e4725115f1aa47af125caafb639bfe 405 SUPERFAMILY SSF103473 9 403 4.84E-67 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS08735 32e4725115f1aa47af125caafb639bfe 405 Pfam PF07690 Major Facilitator Superfamily 29 369 1.4E-49 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS08735 32e4725115f1aa47af125caafb639bfe 405 Gene3D G3DSA:1.20.1250.20 225 403 4.8E-7 T 05-07-2017 K08M4_RS08735 32e4725115f1aa47af125caafb639bfe 405 Gene3D G3DSA:1.20.1250.20 23 206 3.2E-33 T 05-07-2017 K08M4_RS05085 30718f50546fa87498f4f9b6022ba4a4 314 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 16 311 7.1E-92 T 05-07-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS05085 30718f50546fa87498f4f9b6022ba4a4 314 SUPERFAMILY SSF55174 19 71 4.37E-9 T 05-07-2017 K08M4_RS05085 30718f50546fa87498f4f9b6022ba4a4 314 Gene3D G3DSA:3.10.290.10 20 68 4.9E-8 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS05085 30718f50546fa87498f4f9b6022ba4a4 314 SMART SM00363 20 77 3.5E-9 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS05085 30718f50546fa87498f4f9b6022ba4a4 314 Pfam PF00849 RNA pseudouridylate synthase 102 247 6.0E-32 T 05-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS05085 30718f50546fa87498f4f9b6022ba4a4 314 SUPERFAMILY SSF55120 96 309 2.72E-63 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS05085 30718f50546fa87498f4f9b6022ba4a4 314 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 141 155 - T 05-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS05085 30718f50546fa87498f4f9b6022ba4a4 314 Pfam PF01479 S4 domain 20 66 2.3E-10 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS14090 05e6624399e5b87c47fe2e3a142973bf 664 SUPERFAMILY SSF52922 534 663 2.86E-39 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 K08M4_RS14090 05e6624399e5b87c47fe2e3a142973bf 664 SMART SM00861 355 527 9.4E-68 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain K08M4_RS14090 05e6624399e5b87c47fe2e3a142973bf 664 Gene3D G3DSA:3.40.50.970 5 322 6.3E-131 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS14090 05e6624399e5b87c47fe2e3a142973bf 664 ProSitePatterns PS00801 Transketolase signature 1. 12 32 - T 05-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS14090 05e6624399e5b87c47fe2e3a142973bf 664 ProSitePatterns PS00802 Transketolase signature 2. 468 484 - T 05-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS14090 05e6624399e5b87c47fe2e3a142973bf 664 TIGRFAM TIGR00232 tktlase_bact: transketolase 6 659 8.8E-303 T 05-07-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 K08M4_RS14090 05e6624399e5b87c47fe2e3a142973bf 664 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 4 334 8.5E-166 T 05-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS14090 05e6624399e5b87c47fe2e3a142973bf 664 Pfam PF02779 Transketolase, pyrimidine binding domain 354 524 1.3E-45 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain K08M4_RS14090 05e6624399e5b87c47fe2e3a142973bf 664 SUPERFAMILY SSF52518 5 328 8.84E-119 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS14090 05e6624399e5b87c47fe2e3a142973bf 664 Gene3D G3DSA:3.40.50.970 330 533 2.5E-78 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS14090 05e6624399e5b87c47fe2e3a142973bf 664 SUPERFAMILY SSF52518 346 527 5.35E-67 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS14090 05e6624399e5b87c47fe2e3a142973bf 664 Pfam PF02780 Transketolase, C-terminal domain 542 654 3.6E-13 T 05-07-2017 IPR033248 Transketolase, C-terminal domain K08M4_RS14090 05e6624399e5b87c47fe2e3a142973bf 664 Gene3D G3DSA:3.40.50.920 539 663 6.3E-45 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 K08M4_RS09180 3b072e1cf2ecea4c0b7e70509884a5b7 610 SMART SM00278 588 607 18.0 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 K08M4_RS09180 3b072e1cf2ecea4c0b7e70509884a5b7 610 SMART SM00278 556 575 0.56 T 05-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 K08M4_RS09180 3b072e1cf2ecea4c0b7e70509884a5b7 610 SMART SM00465 17 98 1.8E-23 T 05-07-2017 IPR000305 GIY-YIG nuclease superfamily K08M4_RS09180 3b072e1cf2ecea4c0b7e70509884a5b7 610 SUPERFAMILY SSF82771 17 100 5.75E-23 T 05-07-2017 IPR000305 GIY-YIG nuclease superfamily K08M4_RS09180 3b072e1cf2ecea4c0b7e70509884a5b7 610 SUPERFAMILY SSF46600 190 243 7.85E-13 T 05-07-2017 IPR001943 UVR domain GO:0005515 K08M4_RS09180 3b072e1cf2ecea4c0b7e70509884a5b7 610 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 9 589 3.6E-209 T 05-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 K08M4_RS09180 3b072e1cf2ecea4c0b7e70509884a5b7 610 Pfam PF14520 Helix-hairpin-helix domain 558 609 1.1E-10 T 05-07-2017 K08M4_RS09180 3b072e1cf2ecea4c0b7e70509884a5b7 610 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 607 28.347 T 05-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 K08M4_RS09180 3b072e1cf2ecea4c0b7e70509884a5b7 610 SUPERFAMILY SSF47781 521 609 4.77E-19 T 05-07-2017 IPR010994 RuvA domain 2-like K08M4_RS09180 3b072e1cf2ecea4c0b7e70509884a5b7 610 Pfam PF01541 GIY-YIG catalytic domain 18 93 1.9E-12 T 05-07-2017 IPR000305 GIY-YIG nuclease superfamily K08M4_RS09180 3b072e1cf2ecea4c0b7e70509884a5b7 610 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 387 542 1.7E-43 T 05-07-2017 IPR001162 UvrC family homology region K08M4_RS09180 3b072e1cf2ecea4c0b7e70509884a5b7 610 Gene3D G3DSA:3.40.1440.10 17 97 8.0E-12 T 05-07-2017 IPR027299 GIY-YIG domain K08M4_RS09180 3b072e1cf2ecea4c0b7e70509884a5b7 610 Pfam PF02151 UvrB/uvrC motif 206 238 4.7E-9 T 05-07-2017 IPR001943 UVR domain GO:0005515 K08M4_RS09180 3b072e1cf2ecea4c0b7e70509884a5b7 610 Gene3D G3DSA:4.10.860.10 183 243 6.2E-18 T 05-07-2017 IPR001943 UVR domain GO:0005515 K08M4_RS09180 3b072e1cf2ecea4c0b7e70509884a5b7 610 Gene3D G3DSA:1.10.150.20 555 609 3.4E-23 T 05-07-2017 K08M4_RS01535 26f7873eb156d4fa987c4797477fd3a2 130 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 130 31.074 T 05-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01535 26f7873eb156d4fa987c4797477fd3a2 130 Gene3D G3DSA:3.30.1490.10 74 129 2.7E-28 T 05-07-2017 K08M4_RS01535 26f7873eb156d4fa987c4797477fd3a2 130 SUPERFAMILY SSF56047 2 129 2.49E-43 T 05-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01535 26f7873eb156d4fa987c4797477fd3a2 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 05-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01535 26f7873eb156d4fa987c4797477fd3a2 130 Pfam PF00410 Ribosomal protein S8 5 129 2.0E-46 T 05-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01535 26f7873eb156d4fa987c4797477fd3a2 130 Gene3D G3DSA:3.30.1370.30 2 71 1.1E-24 T 05-07-2017 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 Gene3D G3DSA:3.30.70.1430 556 653 6.5E-16 T 05-07-2017 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 Gene3D G3DSA:3.30.2090.10 703 788 8.5E-19 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 SUPERFAMILY SSF82866 792 1009 2.22E-48 T 05-07-2017 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 Gene3D G3DSA:1.20.1640.10 286 498 4.8E-56 T 05-07-2017 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 SUPERFAMILY SSF82866 291 489 2.75E-45 T 05-07-2017 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 Gene3D G3DSA:1.10.3850.10 796 1008 3.9E-62 T 05-07-2017 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 SUPERFAMILY SSF82693 40 134 2.28E-25 T 05-07-2017 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 SUPERFAMILY SSF82714 704 788 2.22E-17 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 SUPERFAMILY SSF82714 183 266 1.57E-14 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 Gene3D G3DSA:3.30.2090.10 183 268 1.4E-16 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 Pfam PF00873 AcrB/AcrD/AcrF family 4 1008 4.4E-280 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.4E-72 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.4E-72 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 5.4E-72 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 5.4E-72 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 5.4E-72 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 PRINTS PR00702 Acriflavin resistance protein family signature 611 625 5.4E-72 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 5.4E-72 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 5.4E-72 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 PRINTS PR00702 Acriflavin resistance protein family signature 541 558 5.4E-72 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 Gene3D G3DSA:3.30.70.1430 40 140 9.0E-30 T 05-07-2017 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 SUPERFAMILY SSF82693 139 181 2.38E-18 T 05-07-2017 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 SUPERFAMILY SSF82693 268 324 2.38E-18 T 05-07-2017 K08M4_RS10240 ac7622488e82cd0bfa377aedac4bf236 1037 SUPERFAMILY SSF82693 554 655 1.91E-17 T 05-07-2017 K08M4_RS09225 0f0603b6ba59b4de5f90067b8cafe570 289 SMART SM00481 3 70 2.6E-17 T 05-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 K08M4_RS09225 0f0603b6ba59b4de5f90067b8cafe570 289 Gene3D G3DSA:3.20.20.140 157 264 8.5E-46 T 05-07-2017 K08M4_RS09225 0f0603b6ba59b4de5f90067b8cafe570 289 Gene3D G3DSA:3.20.20.140 1 88 8.5E-46 T 05-07-2017 K08M4_RS09225 0f0603b6ba59b4de5f90067b8cafe570 289 Pfam PF02811 PHP domain 4 173 6.8E-9 T 05-07-2017 IPR004013 PHP domain GO:0003824 K08M4_RS09225 0f0603b6ba59b4de5f90067b8cafe570 289 SUPERFAMILY SSF89550 165 275 3.27E-54 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 K08M4_RS09225 0f0603b6ba59b4de5f90067b8cafe570 289 SUPERFAMILY SSF89550 1 83 3.27E-54 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 K08M4_RS16150 06fc946163830faadb3fd8799bcbefea 309 Pfam PF03466 LysR substrate binding domain 97 274 2.0E-9 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS16150 06fc946163830faadb3fd8799bcbefea 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 4.2E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS16150 06fc946163830faadb3fd8799bcbefea 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 4.2E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS16150 06fc946163830faadb3fd8799bcbefea 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 4.2E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS16150 06fc946163830faadb3fd8799bcbefea 309 SUPERFAMILY SSF53850 91 269 3.72E-17 T 05-07-2017 K08M4_RS16150 06fc946163830faadb3fd8799bcbefea 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 2.6E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS16150 06fc946163830faadb3fd8799bcbefea 309 SUPERFAMILY SSF46785 5 84 3.37E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16150 06fc946163830faadb3fd8799bcbefea 309 Gene3D G3DSA:1.10.10.10 2 84 2.6E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16150 06fc946163830faadb3fd8799bcbefea 309 Gene3D G3DSA:3.40.190.10 181 265 6.6E-4 T 05-07-2017 K08M4_RS16150 06fc946163830faadb3fd8799bcbefea 309 Gene3D G3DSA:3.40.190.10 91 180 2.0E-9 T 05-07-2017 K08M4_RS21305 ce96b307adee7391573b6cbfe40e4ba0 951 Pfam PF13183 4Fe-4S dicluster domain 550 622 2.4E-10 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain K08M4_RS21305 ce96b307adee7391573b6cbfe40e4ba0 951 Gene3D G3DSA:1.10.45.10 488 517 1.1E-6 T 05-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 K08M4_RS21305 ce96b307adee7391573b6cbfe40e4ba0 951 Pfam PF02913 FAD linked oxidases, C-terminal domain 280 526 1.1E-59 T 05-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 K08M4_RS21305 ce96b307adee7391573b6cbfe40e4ba0 951 Gene3D G3DSA:3.30.43.10 13 102 1.8E-12 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 K08M4_RS21305 ce96b307adee7391573b6cbfe40e4ba0 951 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 552 563 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS21305 ce96b307adee7391573b6cbfe40e4ba0 951 SUPERFAMILY SSF55103 281 534 1.18E-56 T 05-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 K08M4_RS21305 ce96b307adee7391573b6cbfe40e4ba0 951 Gene3D G3DSA:3.30.465.10 110 273 2.0E-19 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 K08M4_RS21305 ce96b307adee7391573b6cbfe40e4ba0 951 Gene3D G3DSA:1.10.1060.10 518 634 1.9E-20 T 05-07-2017 K08M4_RS21305 ce96b307adee7391573b6cbfe40e4ba0 951 Pfam PF02754 Cysteine-rich domain 722 793 0.0014 T 05-07-2017 IPR004017 Cysteine-rich domain K08M4_RS21305 ce96b307adee7391573b6cbfe40e4ba0 951 Pfam PF01565 FAD binding domain 53 189 1.9E-29 T 05-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 K08M4_RS21305 ce96b307adee7391573b6cbfe40e4ba0 951 SUPERFAMILY SSF46548 505 633 4.71E-22 T 05-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 K08M4_RS21305 ce96b307adee7391573b6cbfe40e4ba0 951 SUPERFAMILY SSF56176 17 274 4.5E-57 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 K08M4_RS05600 c718fabdf97552ab92871b01810f92da 271 SUPERFAMILY SSF63380 9 131 2.45E-6 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 K08M4_RS05600 c718fabdf97552ab92871b01810f92da 271 Gene3D G3DSA:3.40.50.80 132 269 3.9E-41 T 05-07-2017 K08M4_RS05600 c718fabdf97552ab92871b01810f92da 271 Pfam PF04954 Siderophore-interacting protein 134 253 6.4E-34 T 05-07-2017 IPR007037 Siderophore-interacting protein K08M4_RS05600 c718fabdf97552ab92871b01810f92da 271 Gene3D G3DSA:2.40.30.10 8 126 2.6E-28 T 05-07-2017 K08M4_RS05600 c718fabdf97552ab92871b01810f92da 271 Pfam PF08021 Siderophore-interacting FAD-binding domain 15 127 1.5E-31 T 05-07-2017 IPR013113 FAD-binding 9, siderophore-interacting K08M4_RS12475 7a8f76f561bd1207f23244caa029323e 470 Gene3D G3DSA:1.10.1060.10 5 149 3.7E-47 T 05-07-2017 K08M4_RS12475 7a8f76f561bd1207f23244caa029323e 470 Gene3D G3DSA:3.50.50.60 237 398 2.5E-50 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS12475 7a8f76f561bd1207f23244caa029323e 470 SUPERFAMILY SSF51971 145 399 3.59E-68 T 05-07-2017 K08M4_RS12475 7a8f76f561bd1207f23244caa029323e 470 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 6 470 7.4E-252 T 05-07-2017 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 K08M4_RS12475 7a8f76f561bd1207f23244caa029323e 470 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 25 134 1.7E-38 T 05-07-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 K08M4_RS12475 7a8f76f561bd1207f23244caa029323e 470 PRINTS PR00419 Adrenodoxin reductase family signature 148 170 5.4E-37 T 05-07-2017 K08M4_RS12475 7a8f76f561bd1207f23244caa029323e 470 PRINTS PR00419 Adrenodoxin reductase family signature 288 302 5.4E-37 T 05-07-2017 K08M4_RS12475 7a8f76f561bd1207f23244caa029323e 470 PRINTS PR00419 Adrenodoxin reductase family signature 171 184 5.4E-37 T 05-07-2017 K08M4_RS12475 7a8f76f561bd1207f23244caa029323e 470 PRINTS PR00419 Adrenodoxin reductase family signature 213 223 5.4E-37 T 05-07-2017 K08M4_RS12475 7a8f76f561bd1207f23244caa029323e 470 PRINTS PR00419 Adrenodoxin reductase family signature 322 335 5.4E-37 T 05-07-2017 K08M4_RS12475 7a8f76f561bd1207f23244caa029323e 470 Gene3D G3DSA:3.40.50.720 150 236 2.5E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS12475 7a8f76f561bd1207f23244caa029323e 470 Gene3D G3DSA:3.40.50.720 399 469 2.5E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS12475 7a8f76f561bd1207f23244caa029323e 470 SUPERFAMILY SSF46548 6 157 1.26E-40 T 05-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 K08M4_RS12475 7a8f76f561bd1207f23244caa029323e 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 147 457 7.7E-23 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS11015 3db0165277ddfc7032ca5cb24bb3813f 156 Pfam PF00578 AhpC/TSA family 7 134 5.0E-33 T 05-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 K08M4_RS11015 3db0165277ddfc7032ca5cb24bb3813f 156 SUPERFAMILY SSF52833 5 152 4.02E-45 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS11015 3db0165277ddfc7032ca5cb24bb3813f 156 Gene3D G3DSA:3.40.30.10 3 151 1.2E-45 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS11390 9948bddaf2fb9985151323ee224734ce 269 Pfam PF03180 NLPA lipoprotein 33 269 3.4E-98 T 05-07-2017 IPR004872 Lipoprotein NlpA family K08M4_RS11390 9948bddaf2fb9985151323ee224734ce 269 SUPERFAMILY SSF53850 32 269 2.11E-80 T 05-07-2017 K08M4_RS11390 9948bddaf2fb9985151323ee224734ce 269 PIRSF PIRSF002854 1 269 1.6E-97 T 05-07-2017 IPR004872 Lipoprotein NlpA family K08M4_RS11390 9948bddaf2fb9985151323ee224734ce 269 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 15 269 1.3E-126 T 05-07-2017 IPR004872 Lipoprotein NlpA family K08M4_RS11390 9948bddaf2fb9985151323ee224734ce 269 Gene3D G3DSA:3.40.190.10 30 161 3.6E-56 T 05-07-2017 K08M4_RS12885 a4078349d8748a37db94d3dcf414936a 602 Gene3D G3DSA:2.30.38.10 401 460 8.5E-20 T 05-07-2017 K08M4_RS12885 a4078349d8748a37db94d3dcf414936a 602 Gene3D G3DSA:3.40.50.980 333 387 8.4E-31 T 05-07-2017 K08M4_RS12885 a4078349d8748a37db94d3dcf414936a 602 Gene3D G3DSA:3.40.50.980 189 280 8.4E-31 T 05-07-2017 K08M4_RS12885 a4078349d8748a37db94d3dcf414936a 602 Pfam PF00501 AMP-binding enzyme 13 466 7.0E-98 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 K08M4_RS12885 a4078349d8748a37db94d3dcf414936a 602 SUPERFAMILY SSF56801 7 285 2.49E-111 T 05-07-2017 K08M4_RS12885 a4078349d8748a37db94d3dcf414936a 602 SUPERFAMILY SSF56801 336 596 2.49E-111 T 05-07-2017 K08M4_RS12885 a4078349d8748a37db94d3dcf414936a 602 Gene3D G3DSA:3.40.50.980 8 188 3.2E-30 T 05-07-2017 K08M4_RS12885 a4078349d8748a37db94d3dcf414936a 602 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 05-07-2017 IPR020845 AMP-binding, conserved site K08M4_RS12285 025a6d2765b0ee48a0b1de7d2d38ba01 263 Pfam PF01925 Sulfite exporter TauE/SafE 10 261 1.7E-50 T 05-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 K08M4_RS16055 0cef55d07ae3ce322f68481b895847a0 523 SUPERFAMILY SSF161098 272 512 3.01E-57 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS16055 0cef55d07ae3ce322f68481b895847a0 523 Gene3D G3DSA:3.10.650.10 204 278 1.4E-33 T 05-07-2017 K08M4_RS16055 0cef55d07ae3ce322f68481b895847a0 523 Gene3D G3DSA:1.10.3720.10 284 519 1.5E-58 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS16055 0cef55d07ae3ce322f68481b895847a0 523 Pfam PF14785 Maltose transport system permease protein MalF P2 domain 109 269 7.3E-57 T 05-07-2017 IPR029345 Maltose transport system permease protein MalF, P2 domain K08M4_RS16055 0cef55d07ae3ce322f68481b895847a0 523 Gene3D G3DSA:1.20.58.370 18 104 2.6E-33 T 05-07-2017 K08M4_RS16055 0cef55d07ae3ce322f68481b895847a0 523 SUPERFAMILY SSF160964 23 269 6.67E-82 T 05-07-2017 K08M4_RS16055 0cef55d07ae3ce322f68481b895847a0 523 Gene3D G3DSA:2.40.430.10 127 203 1.5E-24 T 05-07-2017 K08M4_RS16055 0cef55d07ae3ce322f68481b895847a0 523 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 306 511 2.9E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS11415 9a39ea54a858ba6f0022ac976dfbbb18 521 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 361 519 3.7E-37 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS11415 9a39ea54a858ba6f0022ac976dfbbb18 521 SUPERFAMILY SSF55073 366 520 8.63E-38 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS11415 9a39ea54a858ba6f0022ac976dfbbb18 521 SMART SM00267 351 521 1.4E-37 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS11415 9a39ea54a858ba6f0022ac976dfbbb18 521 Pfam PF00990 Diguanylate cyclase, GGDEF domain 363 517 1.9E-37 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS11415 9a39ea54a858ba6f0022ac976dfbbb18 521 Gene3D G3DSA:3.30.70.270 364 519 9.4E-43 T 05-07-2017 K08M4_RS08695 8c0068ece0cd6e9484c0de2ecca1de77 203 Gene3D G3DSA:3.30.1330.60 78 185 5.5E-30 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS08695 8c0068ece0cd6e9484c0de2ecca1de77 203 Gene3D G3DSA:4.10.1080.10 36 72 2.9E-7 T 05-07-2017 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 K08M4_RS08695 8c0068ece0cd6e9484c0de2ecca1de77 203 SUPERFAMILY SSF103088 54 183 1.18E-29 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS08695 8c0068ece0cd6e9484c0de2ecca1de77 203 PRINTS PR01021 OMPA domain signature 129 145 1.7E-9 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS08695 8c0068ece0cd6e9484c0de2ecca1de77 203 PRINTS PR01021 OMPA domain signature 114 129 1.7E-9 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS08695 8c0068ece0cd6e9484c0de2ecca1de77 203 PRINTS PR01021 OMPA domain signature 84 106 1.7E-9 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS08695 8c0068ece0cd6e9484c0de2ecca1de77 203 Pfam PF00691 OmpA family 83 178 1.1E-19 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS19095 797233f83e445bd92f71f3bb9b017a11 216 SMART SM00448 2 110 8.9E-23 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS19095 797233f83e445bd92f71f3bb9b017a11 216 SUPERFAMILY SSF52172 2 169 3.27E-23 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS19095 797233f83e445bd92f71f3bb9b017a11 216 SUPERFAMILY SSF46894 120 212 9.02E-27 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS19095 797233f83e445bd92f71f3bb9b017a11 216 Gene3D G3DSA:1.10.10.10 121 214 2.8E-28 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19095 797233f83e445bd92f71f3bb9b017a11 216 Pfam PF00072 Response regulator receiver domain 5 110 9.5E-16 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS19095 797233f83e445bd92f71f3bb9b017a11 216 Gene3D G3DSA:3.40.50.2300 1 115 1.8E-22 T 05-07-2017 K08M4_RS19095 797233f83e445bd92f71f3bb9b017a11 216 Pfam PF00486 Transcriptional regulatory protein, C terminal 141 211 1.8E-23 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS19095 797233f83e445bd92f71f3bb9b017a11 216 SMART SM00862 140 211 5.8E-24 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS06345 3b2f831d938ca76df32d7a5958e722a9 325 PIRSF PIRSF034367 1 325 4.0E-193 T 05-07-2017 IPR015004 Protein of unknown function DUF1852 K08M4_RS06345 3b2f831d938ca76df32d7a5958e722a9 325 Pfam PF08908 Domain of unknown function (DUF1852) 1 321 1.3E-182 T 05-07-2017 IPR015004 Protein of unknown function DUF1852 K08M4_RS13125 0de9d0fbd79240c214ae1f55755142d8 240 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 25 5.1E-7 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS13125 0de9d0fbd79240c214ae1f55755142d8 240 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 2 25 8.0E-7 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS13125 0de9d0fbd79240c214ae1f55755142d8 240 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS19610 22d3b1098bb3a1823220afcdd9ea4ecf 116 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 110 1.2E-5 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain K08M4_RS19610 22d3b1098bb3a1823220afcdd9ea4ecf 116 Gene3D G3DSA:3.10.180.10 6 115 7.9E-22 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS19610 22d3b1098bb3a1823220afcdd9ea4ecf 116 SUPERFAMILY SSF54593 5 116 3.71E-19 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS20320 43b457ca076d866ae0e9cfa273c7fce9 207 Pfam PF00929 Exonuclease 10 165 3.2E-28 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS20320 43b457ca076d866ae0e9cfa273c7fce9 207 Gene3D G3DSA:3.30.420.10 7 176 1.7E-53 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS20320 43b457ca076d866ae0e9cfa273c7fce9 207 SUPERFAMILY SSF53098 5 180 2.64E-51 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS20320 43b457ca076d866ae0e9cfa273c7fce9 207 SMART SM00479 8 175 4.2E-35 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS20320 43b457ca076d866ae0e9cfa273c7fce9 207 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 7 189 2.5E-27 T 05-07-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS03510 4e23e28f99979352c73a682f6195dd83 156 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 14 150 7.3E-55 T 05-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS03510 4e23e28f99979352c73a682f6195dd83 156 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 151 6.9E-56 T 05-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS03510 4e23e28f99979352c73a682f6195dd83 156 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 154 31.172 T 05-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS03510 4e23e28f99979352c73a682f6195dd83 156 Gene3D G3DSA:3.40.50.960 3 154 2.4E-65 T 05-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS03510 4e23e28f99979352c73a682f6195dd83 156 SUPERFAMILY SSF52121 4 154 1.13E-60 T 05-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS14240 d84ec8d315343ea7a918495c70b5f905 500 SUPERFAMILY SSF160246 12 78 1.73E-15 T 05-07-2017 K08M4_RS14240 d84ec8d315343ea7a918495c70b5f905 500 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 12 497 9.1E-230 T 05-07-2017 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 K08M4_RS14240 d84ec8d315343ea7a918495c70b5f905 500 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 320 334 - T 05-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 K08M4_RS14240 d84ec8d315343ea7a918495c70b5f905 500 SMART SM00382 253 376 2.8E-6 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS14240 d84ec8d315343ea7a918495c70b5f905 500 Gene3D G3DSA:3.40.50.300 228 498 9.0E-104 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14240 d84ec8d315343ea7a918495c70b5f905 500 SUPERFAMILY SSF52540 107 497 5.28E-107 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14240 d84ec8d315343ea7a918495c70b5f905 500 Gene3D G3DSA:3.30.450.90 92 225 8.2E-55 T 05-07-2017 K08M4_RS14240 d84ec8d315343ea7a918495c70b5f905 500 Pfam PF00437 Type II/IV secretion system protein 127 392 4.7E-88 T 05-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 K08M4_RS21485 5bb0eb38be504a849f8ed13111791eb7 297 SUPERFAMILY SSF46785 1 81 3.59E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21485 5bb0eb38be504a849f8ed13111791eb7 297 Gene3D G3DSA:1.10.10.10 1 80 1.7E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21485 5bb0eb38be504a849f8ed13111791eb7 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 1.8E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS21485 5bb0eb38be504a849f8ed13111791eb7 297 SUPERFAMILY SSF53850 91 276 2.35E-16 T 05-07-2017 K08M4_RS21485 5bb0eb38be504a849f8ed13111791eb7 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.0E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS21485 5bb0eb38be504a849f8ed13111791eb7 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.0E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS21485 5bb0eb38be504a849f8ed13111791eb7 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.0E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS21485 5bb0eb38be504a849f8ed13111791eb7 297 Pfam PF03466 LysR substrate binding domain 91 264 7.9E-10 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS21485 5bb0eb38be504a849f8ed13111791eb7 297 Gene3D G3DSA:3.40.190.10 91 169 4.2E-4 T 05-07-2017 K08M4_RS16270 cd523009309296688a7621c291462bdd 342 Gene3D G3DSA:3.20.20.140 3 341 2.1E-136 T 05-07-2017 K08M4_RS16270 cd523009309296688a7621c291462bdd 342 PIRSF PIRSF001237 1 342 2.9E-142 T 05-07-2017 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 K08M4_RS16270 cd523009309296688a7621c291462bdd 342 Pfam PF01979 Amidohydrolase family 11 309 9.6E-17 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 K08M4_RS16270 cd523009309296688a7621c291462bdd 342 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 4 342 6.9E-141 T 05-07-2017 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 K08M4_RS16270 cd523009309296688a7621c291462bdd 342 Hamap MF_00219 Dihydroorotase [pyrC]. 2 342 44.841 T 05-07-2017 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 K08M4_RS16270 cd523009309296688a7621c291462bdd 342 ProSitePatterns PS00482 Dihydroorotase signature 1. 11 19 - T 05-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 K08M4_RS16270 cd523009309296688a7621c291462bdd 342 ProSitePatterns PS00483 Dihydroorotase signature 2. 244 255 - T 05-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 K08M4_RS16270 cd523009309296688a7621c291462bdd 342 SUPERFAMILY SSF51556 1 342 1.02E-145 T 05-07-2017 IPR032466 Metal-dependent hydrolase K08M4_RS08670 4a6db92022805bdba480bcb9c5d5159e 400 Hamap MF_01838 Trans-2-enoyl-CoA reductase [NADH] [fabV]. 1 395 56.939 T 05-07-2017 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS08670 4a6db92022805bdba480bcb9c5d5159e 400 Pfam PF07055 Enoyl reductase FAD binding domain 326 389 7.0E-30 T 05-07-2017 IPR024906 Enoyl reductase FAD binding domain KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS08670 4a6db92022805bdba480bcb9c5d5159e 400 Pfam PF12242 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2 80 9.9E-37 T 05-07-2017 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS08670 4a6db92022805bdba480bcb9c5d5159e 400 Pfam PF12241 Trans-2-enoyl-CoA reductase catalytic region 82 317 7.4E-113 T 05-07-2017 IPR024910 Trans-2-enoyl-CoA reductase catalytic domain, putative KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS08670 4a6db92022805bdba480bcb9c5d5159e 400 Gene3D G3DSA:3.40.50.720 42 282 2.6E-5 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS00580 3140e4e1758ee293ae7d73199c430de9 280 Gene3D G3DSA:1.20.1540.10 97 269 1.4E-32 T 05-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 K08M4_RS00580 3140e4e1758ee293ae7d73199c430de9 280 TIGRFAM TIGR04239 rhombo_GlpG: rhomboid family protease GlpG 3 272 1.2E-117 T 05-07-2017 IPR023662 Rhomboid protease GlpG GO:0004252|GO:0006508|GO:0016021 K08M4_RS00580 3140e4e1758ee293ae7d73199c430de9 280 Pfam PF12122 Cytoplasmic N-terminal domain of rhomboid serine protease 1 87 6.8E-32 T 05-07-2017 IPR022732 Peptidase S54, GlpG peptidase, N-terminal GO:0004252|GO:0016021 K08M4_RS00580 3140e4e1758ee293ae7d73199c430de9 280 Pfam PF01694 Rhomboid family 134 271 6.3E-31 T 05-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 K08M4_RS00580 3140e4e1758ee293ae7d73199c430de9 280 SUPERFAMILY SSF144091 96 272 1.2E-39 T 05-07-2017 K08M4_RS00910 75842fbd48b5b6e737ad60af8797765c 322 Gene3D G3DSA:3.20.20.70 7 244 5.9E-84 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS00910 75842fbd48b5b6e737ad60af8797765c 322 SUPERFAMILY SSF51395 10 319 6.96E-90 T 05-07-2017 K08M4_RS00910 75842fbd48b5b6e737ad60af8797765c 322 Gene3D G3DSA:1.10.1200.80 252 320 1.2E-17 T 05-07-2017 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 K08M4_RS00910 75842fbd48b5b6e737ad60af8797765c 322 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 05-07-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 K08M4_RS00910 75842fbd48b5b6e737ad60af8797765c 322 Pfam PF01207 Dihydrouridine synthase (Dus) 13 318 6.3E-110 T 05-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 K08M4_RS00910 75842fbd48b5b6e737ad60af8797765c 322 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 320 1.1E-132 T 05-07-2017 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 K08M4_RS00910 75842fbd48b5b6e737ad60af8797765c 322 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 321 49.575 T 05-07-2017 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 K08M4_RS00910 75842fbd48b5b6e737ad60af8797765c 322 PIRSF PIRSF006621 1 321 2.4E-103 T 05-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 K08M4_RS17850 c108bf042be21293fe554899edf30f8a 576 SUPERFAMILY SSF55874 446 563 5.89E-17 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS17850 c108bf042be21293fe554899edf30f8a 576 Pfam PF07730 Histidine kinase 367 435 1.1E-16 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 K08M4_RS17850 c108bf042be21293fe554899edf30f8a 576 SMART SM00387 476 569 2.0E-9 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS17850 c108bf042be21293fe554899edf30f8a 576 Pfam PF00672 HAMP domain 158 223 1.3E-11 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS17850 c108bf042be21293fe554899edf30f8a 576 SUPERFAMILY SSF158472 178 223 1.57E-8 T 05-07-2017 K08M4_RS17850 c108bf042be21293fe554899edf30f8a 576 Gene3D G3DSA:3.30.565.10 447 565 6.8E-11 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS17850 c108bf042be21293fe554899edf30f8a 576 SMART SM00304 176 228 5.8E-10 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS17850 c108bf042be21293fe554899edf30f8a 576 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 478 565 1.3E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS17850 c108bf042be21293fe554899edf30f8a 576 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 34 128 4.4E-21 T 05-07-2017 IPR029095 NarX-like, N-terminal K08M4_RS17850 c108bf042be21293fe554899edf30f8a 576 PIRSF PIRSF003167 3 574 1.6E-168 T 05-07-2017 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 K08M4_RS04095 2b430ca603d435dc010c5faafb97cd5c 399 SUPERFAMILY SSF64518 1 399 4.97E-99 T 05-07-2017 K08M4_RS04095 2b430ca603d435dc010c5faafb97cd5c 399 Gene3D G3DSA:1.20.1330.10 301 354 1.3E-58 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS04095 2b430ca603d435dc010c5faafb97cd5c 399 Gene3D G3DSA:1.20.1330.10 54 171 1.3E-58 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS04095 2b430ca603d435dc010c5faafb97cd5c 399 Pfam PF00700 Bacterial flagellin C-terminal helical region 313 398 2.1E-26 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS04095 2b430ca603d435dc010c5faafb97cd5c 399 PRINTS PR00207 Flagellin signature 76 95 9.8E-25 T 05-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 K08M4_RS04095 2b430ca603d435dc010c5faafb97cd5c 399 PRINTS PR00207 Flagellin signature 111 134 9.8E-25 T 05-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 K08M4_RS04095 2b430ca603d435dc010c5faafb97cd5c 399 PRINTS PR00207 Flagellin signature 37 54 9.8E-25 T 05-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 K08M4_RS04095 2b430ca603d435dc010c5faafb97cd5c 399 Pfam PF07196 Flagellin hook IN motif 197 246 4.7E-10 T 05-07-2017 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 K08M4_RS04095 2b430ca603d435dc010c5faafb97cd5c 399 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 8.3E-43 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS06680 01385aa3095c3199f37f8566610d862d 313 PIRSF PIRSF000450 1 309 8.4E-146 T 05-07-2017 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 K08M4_RS06680 01385aa3095c3199f37f8566610d862d 313 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 301 5.9E-162 T 05-07-2017 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 K08M4_RS06680 01385aa3095c3199f37f8566610d862d 313 Hamap MF_00295 Homoserine O-succinyltransferase [metA]. 1 301 52.966 T 05-07-2017 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 K08M4_RS06680 01385aa3095c3199f37f8566610d862d 313 SUPERFAMILY SSF52317 17 297 7.91E-101 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS06680 01385aa3095c3199f37f8566610d862d 313 Gene3D G3DSA:3.40.50.880 34 301 1.6E-121 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS06680 01385aa3095c3199f37f8566610d862d 313 Pfam PF04204 Homoserine O-succinyltransferase 2 299 4.9E-134 T 05-07-2017 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 K08M4_RS06680 01385aa3095c3199f37f8566610d862d 313 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 1.0E-126 T 05-07-2017 K08M4_RS13055 4dd06351dfe4f05bd98e3d5d64228bbf 244 Pfam PF00849 RNA pseudouridylate synthase 22 167 1.2E-26 T 05-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS13055 4dd06351dfe4f05bd98e3d5d64228bbf 244 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 60 74 - T 05-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS13055 4dd06351dfe4f05bd98e3d5d64228bbf 244 SUPERFAMILY SSF55120 14 220 1.25E-62 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS14840 a3cb93c33024834798f7678b895376df 472 SUPERFAMILY SSF54862 107 129 7.78E-31 T 05-07-2017 K08M4_RS14840 a3cb93c33024834798f7678b895376df 472 SUPERFAMILY SSF54862 175 334 7.78E-31 T 05-07-2017 K08M4_RS14840 a3cb93c33024834798f7678b895376df 472 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 274 285 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS14840 a3cb93c33024834798f7678b895376df 472 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 357 469 2.4E-29 T 05-07-2017 IPR032879 FixG, C-terminal immunoglobulin-like domain K08M4_RS14840 a3cb93c33024834798f7678b895376df 472 Gene3D G3DSA:1.10.1060.10 225 282 2.3E-7 T 05-07-2017 K08M4_RS14840 a3cb93c33024834798f7678b895376df 472 Gene3D G3DSA:3.30.70.20 283 320 2.3E-6 T 05-07-2017 K08M4_RS14840 a3cb93c33024834798f7678b895376df 472 Pfam PF13746 4Fe-4S dicluster domain 222 326 2.0E-41 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain K08M4_RS14840 a3cb93c33024834798f7678b895376df 472 Gene3D G3DSA:2.60.40.10 356 470 1.9E-34 T 05-07-2017 IPR013783 Immunoglobulin-like fold K08M4_RS14840 a3cb93c33024834798f7678b895376df 472 Pfam PF12801 4Fe-4S binding domain 97 136 1.3E-8 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain K08M4_RS14840 a3cb93c33024834798f7678b895376df 472 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 43 470 3.4E-169 T 05-07-2017 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021 K08M4_RS19280 d6ee7dd28f3e96451cdfe3772f3bfab3 164 Gene3D G3DSA:3.40.630.30 3 159 4.0E-35 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS19280 d6ee7dd28f3e96451cdfe3772f3bfab3 164 SUPERFAMILY SSF55729 3 159 1.86E-35 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS19280 d6ee7dd28f3e96451cdfe3772f3bfab3 164 Pfam PF13673 Acetyltransferase (GNAT) domain 29 156 1.7E-23 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS04400 839db655f4b454a8f2f891f5fb03afd3 481 Pfam PF00672 HAMP domain 206 273 6.2E-13 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS04400 839db655f4b454a8f2f891f5fb03afd3 481 SUPERFAMILY SSF55874 344 477 3.27E-30 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS04400 839db655f4b454a8f2f891f5fb03afd3 481 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 377 476 3.3E-18 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS04400 839db655f4b454a8f2f891f5fb03afd3 481 Gene3D G3DSA:1.10.287.130 267 328 1.3E-11 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS04400 839db655f4b454a8f2f891f5fb03afd3 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 457 1.1E-10 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS04400 839db655f4b454a8f2f891f5fb03afd3 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 436 1.1E-10 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS04400 839db655f4b454a8f2f891f5fb03afd3 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 422 1.1E-10 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS04400 839db655f4b454a8f2f891f5fb03afd3 481 SMART SM00387 374 479 2.9E-26 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS04400 839db655f4b454a8f2f891f5fb03afd3 481 SMART SM00304 224 276 2.8E-6 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS04400 839db655f4b454a8f2f891f5fb03afd3 481 SUPERFAMILY SSF47384 261 326 1.24E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS04400 839db655f4b454a8f2f891f5fb03afd3 481 Gene3D G3DSA:3.30.565.10 344 477 4.9E-29 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS02575 1e437134900bd142230fd2c9c9abaca4 305 Gene3D G3DSA:3.30.420.40 126 271 9.9E-22 T 05-07-2017 K08M4_RS02575 1e437134900bd142230fd2c9c9abaca4 305 SUPERFAMILY SSF53067 126 294 5.62E-25 T 05-07-2017 K08M4_RS02575 1e437134900bd142230fd2c9c9abaca4 305 Pfam PF00480 ROK family 124 296 4.8E-19 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 K08M4_RS00835 7a1a12d766bee0f9c9e4b7b80afbaabf 1400 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 1.6E-89 T 05-07-2017 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00835 7a1a12d766bee0f9c9e4b7b80afbaabf 1400 Gene3D G3DSA:2.40.40.20 417 489 2.5E-37 T 05-07-2017 K08M4_RS00835 7a1a12d766bee0f9c9e4b7b80afbaabf 1400 Gene3D G3DSA:2.40.40.20 349 376 2.5E-37 T 05-07-2017 K08M4_RS00835 7a1a12d766bee0f9c9e4b7b80afbaabf 1400 SUPERFAMILY SSF64484 1133 1364 0.0 T 05-07-2017 K08M4_RS00835 7a1a12d766bee0f9c9e4b7b80afbaabf 1400 SUPERFAMILY SSF64484 16 944 0.0 T 05-07-2017 K08M4_RS00835 7a1a12d766bee0f9c9e4b7b80afbaabf 1400 SMART SM00663 235 514 2.1E-185 T 05-07-2017 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00835 7a1a12d766bee0f9c9e4b7b80afbaabf 1400 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 763 5.5E-19 T 05-07-2017 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00835 7a1a12d766bee0f9c9e4b7b80afbaabf 1400 Pfam PF00623 RNA polymerase Rpb1, domain 2 388 485 1.0E-27 T 05-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00835 7a1a12d766bee0f9c9e4b7b80afbaabf 1400 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 395 5.6E-8 T 05-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00835 7a1a12d766bee0f9c9e4b7b80afbaabf 1400 Gene3D G3DSA:2.40.50.100 1156 1209 3.1E-7 T 05-07-2017 K08M4_RS00835 7a1a12d766bee0f9c9e4b7b80afbaabf 1400 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 644 7.0E-27 T 05-07-2017 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00835 7a1a12d766bee0f9c9e4b7b80afbaabf 1400 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1314 4.4E-77 T 05-07-2017 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00835 7a1a12d766bee0f9c9e4b7b80afbaabf 1400 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 15 1375 10.422 T 05-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS00835 7a1a12d766bee0f9c9e4b7b80afbaabf 1400 Hamap MF_01323 DNA-directed RNA polymerase subunit gamma [rpoC1]. 13 588 32.347 T 05-07-2017 K08M4_RS00835 7a1a12d766bee0f9c9e4b7b80afbaabf 1400 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1366 0.0 T 05-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 K08M4_RS03855 f1d6e44c5c5e35f1ea690d4d541afd0e 46 Pfam PF11346 Protein of unknown function (DUF3149) 4 43 1.8E-14 T 05-07-2017 IPR021494 Protein of unknown function DUF3149 K08M4_RS06040 9cf94f1f63ebdacb30d3e77a82f36ee4 510 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 05-07-2017 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 K08M4_RS06040 9cf94f1f63ebdacb30d3e77a82f36ee4 510 SUPERFAMILY SSF48557 5 504 2.28E-189 T 05-07-2017 IPR008948 L-Aspartase-like GO:0003824 K08M4_RS06040 9cf94f1f63ebdacb30d3e77a82f36ee4 510 Gene3D G3DSA:1.10.275.10 6 197 9.6E-73 T 05-07-2017 IPR024083 Fumarase/histidase, N-terminal K08M4_RS06040 9cf94f1f63ebdacb30d3e77a82f36ee4 510 Gene3D G3DSA:1.20.200.10 198 494 9.6E-127 T 05-07-2017 K08M4_RS06040 9cf94f1f63ebdacb30d3e77a82f36ee4 510 Pfam PF00221 Aromatic amino acid lyase 12 470 2.9E-187 T 05-07-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 K08M4_RS06040 9cf94f1f63ebdacb30d3e77a82f36ee4 510 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 3 504 43.707 T 05-07-2017 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 K08M4_RS06040 9cf94f1f63ebdacb30d3e77a82f36ee4 510 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 6 500 7.5E-212 T 05-07-2017 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 Gene3D G3DSA:3.30.565.10 283 430 9.6E-47 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 SMART SM00387 321 432 2.0E-39 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 385 1.8E-19 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 1.8E-19 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 429 1.8E-19 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 410 1.8E-19 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 322 430 1.4E-29 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 Gene3D G3DSA:1.10.287.130 201 270 1.0E-14 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 Gene3D G3DSA:3.40.50.2300 452 571 2.6E-40 T 05-07-2017 K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 SUPERFAMILY SSF47384 195 274 4.32E-20 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 Pfam PF00512 His Kinase A (phospho-acceptor) domain 209 274 2.4E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 SUPERFAMILY SSF52172 453 571 1.02E-38 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 Pfam PF00072 Response regulator receiver domain 456 567 3.5E-29 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 SMART SM00388 209 274 5.9E-21 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 SMART SM00448 454 567 4.4E-41 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS07680 4875a8546407246ec817feff66fb0116 574 SUPERFAMILY SSF55874 263 430 1.96E-46 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS05695 0e2231ee1fd490ce8aa74ed6431bd327 799 Pfam PF08497 Radical SAM N-terminal 24 372 1.2E-139 T 05-07-2017 IPR013704 Uncharacterised protein family UPF0313, N-terminal K08M4_RS05695 0e2231ee1fd490ce8aa74ed6431bd327 799 SMART SM00729 369 619 1.4E-4 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 K08M4_RS05695 0e2231ee1fd490ce8aa74ed6431bd327 799 Gene3D G3DSA:3.80.30.20 367 620 3.4E-47 T 05-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe K08M4_RS05695 0e2231ee1fd490ce8aa74ed6431bd327 799 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 24 638 8.3E-259 T 05-07-2017 IPR022946 Uncharacterised protein family UPF0313 K08M4_RS05695 0e2231ee1fd490ce8aa74ed6431bd327 799 Pfam PF11842 Domain of unknown function (DUF3362) 587 734 3.7E-41 T 05-07-2017 IPR024560 Uncharacterised protein family UPF0313, C-terminal K08M4_RS05695 0e2231ee1fd490ce8aa74ed6431bd327 799 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 23 688 47.848 T 05-07-2017 IPR022946 Uncharacterised protein family UPF0313 K08M4_RS05695 0e2231ee1fd490ce8aa74ed6431bd327 799 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 373 393 - T 05-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 K08M4_RS05695 0e2231ee1fd490ce8aa74ed6431bd327 799 SUPERFAMILY SSF102114 372 433 2.09E-10 T 05-07-2017 K08M4_RS05695 0e2231ee1fd490ce8aa74ed6431bd327 799 SUPERFAMILY SSF102114 463 607 2.09E-10 T 05-07-2017 K08M4_RS05695 0e2231ee1fd490ce8aa74ed6431bd327 799 Pfam PF04055 Radical SAM superfamily 373 578 2.5E-19 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 Pfam PF12705 PD-(D/E)XK nuclease superfamily 978 1182 1.0E-7 T 05-07-2017 K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 Gene3D G3DSA:3.40.50.300 464 597 1.5E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 Gene3D G3DSA:3.40.50.300 749 889 1.5E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 Gene3D G3DSA:1.10.486.10 600 748 3.8E-50 T 05-07-2017 K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 Gene3D G3DSA:3.40.50.300 136 165 3.3E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 Gene3D G3DSA:3.40.50.300 15 98 3.3E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 Gene3D G3DSA:3.40.50.300 364 463 3.3E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 Pfam PF00580 UvrD/REP helicase N-terminal domain 22 450 1.3E-58 T 05-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 Pfam PF13361 UvrD-like helicase C-terminal domain 456 829 4.9E-18 T 05-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 SUPERFAMILY SSF52540 339 841 2.31E-110 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 SUPERFAMILY SSF52540 21 96 2.31E-110 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 SUPERFAMILY SSF52540 134 218 2.31E-110 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 15 1201 0.0 T 05-07-2017 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 SUPERFAMILY SSF52980 921 1203 2.25E-83 T 05-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 Gene3D G3DSA:1.10.3170.10 171 363 2.0E-60 T 05-07-2017 K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 13 1202 22.831 T 05-07-2017 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 K08M4_RS11585 19c11491ee2fa752228921abc67fee62 1224 Gene3D G3DSA:3.90.320.10 911 1204 1.7E-98 T 05-07-2017 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 K08M4_RS00600 210dc080989a398537ecf77c9ece28a6 807 TIGRFAM TIGR03703 plsB: glycerol-3-phosphate O-acyltransferase 11 799 0.0 T 05-07-2017 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 K08M4_RS00600 210dc080989a398537ecf77c9ece28a6 807 SUPERFAMILY SSF69593 236 488 6.15E-26 T 05-07-2017 K08M4_RS00600 210dc080989a398537ecf77c9ece28a6 807 Gene3D G3DSA:3.40.1130.10 284 443 2.3E-4 T 05-07-2017 K08M4_RS00600 210dc080989a398537ecf77c9ece28a6 807 Hamap MF_00393 Glycerol-3-phosphate acyltransferase [plsB]. 13 807 31.416 T 05-07-2017 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 K08M4_RS00600 210dc080989a398537ecf77c9ece28a6 807 Pfam PF01553 Acyltransferase 288 424 1.4E-23 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 K08M4_RS00600 210dc080989a398537ecf77c9ece28a6 807 SMART SM00563 300 427 2.2E-26 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 K08M4_RS00600 210dc080989a398537ecf77c9ece28a6 807 PIRSF PIRSF500064 2 807 0.0 T 05-07-2017 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 K08M4_RS00600 210dc080989a398537ecf77c9ece28a6 807 PIRSF PIRSF000437 19 807 0.0 T 05-07-2017 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166 K08M4_RS17300 5c385f9ec585e4d8c9050968a12cbd9d 188 SUPERFAMILY SSF103088 79 186 1.01E-21 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS17300 5c385f9ec585e4d8c9050968a12cbd9d 188 Pfam PF00691 OmpA family 89 179 3.7E-15 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS17300 5c385f9ec585e4d8c9050968a12cbd9d 188 Gene3D G3DSA:3.30.1330.60 85 186 6.3E-20 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS17300 5c385f9ec585e4d8c9050968a12cbd9d 188 PRINTS PR01021 OMPA domain signature 116 131 5.8E-8 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS17300 5c385f9ec585e4d8c9050968a12cbd9d 188 PRINTS PR01021 OMPA domain signature 131 147 5.8E-8 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS10165 29d1ce88d0d3f9b25fcc590ae50e49e1 381 SUPERFAMILY SSF53756 16 378 6.67E-62 T 05-07-2017 K08M4_RS10165 29d1ce88d0d3f9b25fcc590ae50e49e1 381 Gene3D G3DSA:3.40.50.2000 193 353 5.4E-24 T 05-07-2017 K08M4_RS10165 29d1ce88d0d3f9b25fcc590ae50e49e1 381 Pfam PF00534 Glycosyl transferases group 1 191 358 7.5E-29 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 Gene3D G3DSA:1.10.460.10 497 614 1.8E-51 T 05-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 Gene3D G3DSA:1.10.460.10 162 218 1.8E-51 T 05-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 SMART SM00437 284 565 1.1E-84 T 05-07-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 SUPERFAMILY SSF56712 3 613 4.19E-182 T 05-07-2017 IPR023405 DNA topoisomerase, type IA, core domain K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 627 1.1E-235 T 05-07-2017 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 Pfam PF01751 Toprim domain 4 124 2.3E-15 T 05-07-2017 IPR006171 Toprim domain K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 SMART SM00436 129 224 2.6E-29 T 05-07-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 Pfam PF01131 DNA topoisomerase 160 600 3.1E-116 T 05-07-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 Hamap MF_00953 DNA topoisomerase 3 [topB]. 2 649 63.442 T 05-07-2017 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 SMART SM00493 2 125 4.1E-30 T 05-07-2017 IPR006171 Toprim domain K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 528 542 1.7E-25 T 05-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 1.7E-25 T 05-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 327 336 1.7E-25 T 05-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 408 424 1.7E-25 T 05-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 194 212 1.7E-25 T 05-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 321 336 - T 05-07-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 Gene3D G3DSA:2.70.20.10 374 495 4.7E-41 T 05-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 Gene3D G3DSA:2.70.20.10 219 256 4.7E-41 T 05-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 K08M4_RS04715 90ec87fabafbb8e50ce922c6258968b2 653 Gene3D G3DSA:3.40.50.140 3 154 6.6E-45 T 05-07-2017 IPR006171 Toprim domain K08M4_RS02910 289677643b3772c2d64f03001096bd93 799 Gene3D G3DSA:1.10.3810.10 194 371 6.5E-68 T 05-07-2017 K08M4_RS02910 289677643b3772c2d64f03001096bd93 799 Pfam PF14814 Bifunctional transglycosylase second domain 102 185 9.2E-26 T 05-07-2017 IPR028166 Bifunctional transglycosylase second domain KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 K08M4_RS02910 289677643b3772c2d64f03001096bd93 799 Gene3D G3DSA:3.30.2060.10 100 189 4.8E-28 T 05-07-2017 K08M4_RS02910 289677643b3772c2d64f03001096bd93 799 SUPERFAMILY SSF56601 351 373 2.29E-109 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS02910 289677643b3772c2d64f03001096bd93 799 SUPERFAMILY SSF56601 401 785 2.29E-109 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS02910 289677643b3772c2d64f03001096bd93 799 SUPERFAMILY SSF53955 194 390 1.24E-68 T 05-07-2017 IPR023346 Lysozyme-like domain K08M4_RS02910 289677643b3772c2d64f03001096bd93 799 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 57 779 0.0 T 05-07-2017 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 K08M4_RS02910 289677643b3772c2d64f03001096bd93 799 PIRSF PIRSF002799 18 799 0.0 T 05-07-2017 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 K08M4_RS02910 289677643b3772c2d64f03001096bd93 799 Gene3D G3DSA:3.40.710.10 372 771 1.8E-105 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS02910 289677643b3772c2d64f03001096bd93 799 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 202 736 3.3E-154 T 05-07-2017 K08M4_RS02910 289677643b3772c2d64f03001096bd93 799 Pfam PF00912 Transglycosylase 197 368 6.3E-60 T 05-07-2017 IPR001264 Glycosyl transferase, family 51 K08M4_RS02910 289677643b3772c2d64f03001096bd93 799 Pfam PF00905 Penicillin binding protein transpeptidase domain 461 700 2.5E-25 T 05-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 K08M4_RS04880 74ab89d34f1ef3aac4123aa6d01718f9 197 SUPERFAMILY SSF54862 37 173 2.07E-30 T 05-07-2017 K08M4_RS04880 74ab89d34f1ef3aac4123aa6d01718f9 197 PIRSF PIRSF005784 3 188 4.3E-86 T 05-07-2017 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 K08M4_RS04880 74ab89d34f1ef3aac4123aa6d01718f9 197 Hamap MF_00463 Electron transport complex subunit RsxB [rsxB]. 4 182 42.884 T 05-07-2017 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 K08M4_RS04880 74ab89d34f1ef3aac4123aa6d01718f9 197 Gene3D G3DSA:1.10.1060.10 47 122 9.4E-6 T 05-07-2017 K08M4_RS04880 74ab89d34f1ef3aac4123aa6d01718f9 197 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 114 125 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS04880 74ab89d34f1ef3aac4123aa6d01718f9 197 Pfam PF14697 4Fe-4S dicluster domain 107 161 6.9E-18 T 05-07-2017 K08M4_RS04880 74ab89d34f1ef3aac4123aa6d01718f9 197 Gene3D G3DSA:3.30.70.20 123 175 7.6E-17 T 05-07-2017 K08M4_RS04880 74ab89d34f1ef3aac4123aa6d01718f9 197 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 1 187 1.1E-86 T 05-07-2017 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 K08M4_RS04880 74ab89d34f1ef3aac4123aa6d01718f9 197 Pfam PF04060 Putative Fe-S cluster 44 75 8.1E-15 T 05-07-2017 IPR007202 4Fe-4S domain GO:0051536 K08M4_RS04880 74ab89d34f1ef3aac4123aa6d01718f9 197 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 144 155 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 Pfam PF00009 Elongation factor Tu GTP binding domain 2 181 6.6E-53 T 05-07-2017 K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 Gene3D G3DSA:3.30.70.240 401 489 7.7E-22 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 Hamap MF_00071 Elongation factor 4 [lepA]. 1 597 305.055 T 05-07-2017 IPR006297 Elongation factor 4 GO:0005525 K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 05-07-2017 IPR031157 Tr-type G domain, conserved site K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 Gene3D G3DSA:3.30.70.870 291 369 6.5E-26 T 05-07-2017 K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 PRINTS PR00315 GTP-binding elongation factor signature 6 19 3.8E-14 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 PRINTS PR00315 GTP-binding elongation factor signature 90 101 3.8E-14 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 PRINTS PR00315 GTP-binding elongation factor signature 126 135 3.8E-14 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 PRINTS PR00315 GTP-binding elongation factor signature 74 84 3.8E-14 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 PRINTS PR00315 GTP-binding elongation factor signature 49 57 3.8E-14 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 176 3.4E-18 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 Pfam PF06421 GTP-binding protein LepA C-terminus 487 592 1.8E-48 T 05-07-2017 IPR013842 GTP-binding protein LepA, C-terminal K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 SUPERFAMILY SSF54980 399 493 4.8E-25 T 05-07-2017 IPR009022 Elongation factor G, III-V domain K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 SUPERFAMILY SSF52540 2 205 1.9E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 Gene3D G3DSA:3.40.50.300 2 192 6.7E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 Pfam PF03144 Elongation factor Tu domain 2 205 275 4.2E-10 T 05-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 Pfam PF00679 Elongation factor G C-terminus 399 482 3.4E-20 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 SUPERFAMILY SSF54980 292 370 1.62E-18 T 05-07-2017 IPR009022 Elongation factor G, III-V domain K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 SUPERFAMILY SSF50447 165 288 4.37E-29 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 TIGRFAM TIGR01393 lepA: elongation factor 4 2 594 1.4E-299 T 05-07-2017 IPR006297 Elongation factor 4 GO:0005525 K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 Gene3D G3DSA:2.40.30.10 193 289 8.7E-23 T 05-07-2017 K08M4_RS02445 ad7a5b9765124bf7bc2893a9f5e83c2b 597 SMART SM00838 398 486 0.0042 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 SUPERFAMILY SSF81923 1 142 4.84E-59 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 SUPERFAMILY SSF52540 441 745 1.46E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 215 328 5.8E-12 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 Gene3D G3DSA:1.10.8.60 356 440 2.0E-30 T 05-07-2017 K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 738 0.0 T 05-07-2017 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 522 540 - T 05-07-2017 IPR028299 ClpA/B, conserved site 2 K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 62 1.3E-13 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 Gene3D G3DSA:1.10.8.60 667 752 4.5E-29 T 05-07-2017 K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 SMART SM01086 657 746 1.7E-34 T 05-07-2017 IPR019489 Clp ATPase, C-terminal K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 657 737 1.2E-23 T 05-07-2017 IPR019489 Clp ATPase, C-terminal K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 566 584 4.9E-36 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 495 513 4.9E-36 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 599 613 4.9E-36 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 537 555 4.9E-36 T 05-07-2017 IPR001270 ClpA/B family GO:0005524 K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 Pfam PF07724 AAA domain (Cdc48 subfamily) 490 651 9.4E-47 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 Gene3D G3DSA:1.10.1780.10 1 142 1.2E-44 T 05-07-2017 IPR004176 Clp, N-terminal GO:0019538 K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 SMART SM00382 491 658 1.5E-6 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 SMART SM00382 210 355 6.5E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 Gene3D G3DSA:3.40.50.300 173 353 1.1E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 Gene3D G3DSA:3.40.50.300 446 666 1.7E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 SUPERFAMILY SSF52540 171 429 1.41E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05370 203544998b28dfb8063b0ba0fcb99a8f 757 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 306 318 - T 05-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 K08M4_RS13205 1ee02a73174951fbcb9b73361b88734b 215 SUPERFAMILY SSF46894 146 211 5.78E-19 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS13205 1ee02a73174951fbcb9b73361b88734b 215 Gene3D G3DSA:1.10.10.10 150 212 4.9E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS13205 1ee02a73174951fbcb9b73361b88734b 215 SMART SM00421 152 209 1.0E-19 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS13205 1ee02a73174951fbcb9b73361b88734b 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 2.5E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS13205 1ee02a73174951fbcb9b73361b88734b 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 2.5E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS13205 1ee02a73174951fbcb9b73361b88734b 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 2.5E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS13205 1ee02a73174951fbcb9b73361b88734b 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 1.6E-19 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Gene3D G3DSA:3.40.50.140 1 169 3.1E-55 T 05-07-2017 IPR006171 Toprim domain K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 727 53.29 T 05-07-2017 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Pfam PF01751 Toprim domain 5 148 1.2E-32 T 05-07-2017 IPR006171 Toprim domain K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Pfam PF08272 Topoisomerase I zinc-ribbon-like 828 868 3.1E-19 T 05-07-2017 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Pfam PF08272 Topoisomerase I zinc-ribbon-like 761 797 3.8E-11 T 05-07-2017 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Gene3D G3DSA:3.30.65.10 711 748 6.4E-9 T 05-07-2017 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Gene3D G3DSA:3.30.65.10 601 628 3.1E-10 T 05-07-2017 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Gene3D G3DSA:3.30.65.10 749 810 4.1E-27 T 05-07-2017 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 639 1.2E-245 T 05-07-2017 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Pfam PF01131 DNA topoisomerase 163 570 4.3E-126 T 05-07-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 320 329 3.6E-36 T 05-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 495 509 3.6E-36 T 05-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 112 125 3.6E-36 T 05-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 197 215 3.6E-36 T 05-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 396 412 3.6E-36 T 05-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Gene3D G3DSA:2.70.20.10 219 342 3.9E-35 T 05-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Gene3D G3DSA:2.70.20.10 344 478 3.9E-30 T 05-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 SUPERFAMILY SSF57783 704 747 3.57E-5 T 05-07-2017 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 SMART SM00436 139 227 1.4E-45 T 05-07-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 SMART SM00493 3 138 4.9E-33 T 05-07-2017 IPR006171 Toprim domain K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 SUPERFAMILY SSF56712 3 614 8.37E-196 T 05-07-2017 IPR023405 DNA topoisomerase, type IA, core domain K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 713 749 7.2E-9 T 05-07-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 602 627 3.4E-5 T 05-07-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Gene3D G3DSA:2.20.25.10 813 869 1.5E-29 T 05-07-2017 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 SMART SM00437 278 532 7.8E-119 T 05-07-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 SUPERFAMILY SSF57783 748 811 1.21E-19 T 05-07-2017 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 SUPERFAMILY SSF57783 813 869 5.61E-22 T 05-07-2017 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Gene3D G3DSA:1.10.460.10 170 217 1.2E-58 T 05-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 Gene3D G3DSA:1.10.460.10 479 600 1.2E-58 T 05-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 K08M4_RS05405 4da2bea41f53b183b5806c0503d1472c 876 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 315 329 - T 05-07-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 K08M4_RS10760 f101fde7dab0c966da130bdbfe5a7982 249 SUPERFAMILY SSF56300 146 235 2.09E-23 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS10760 f101fde7dab0c966da130bdbfe5a7982 249 SUPERFAMILY SSF56300 2 109 2.09E-23 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS10760 f101fde7dab0c966da130bdbfe5a7982 249 Gene3D G3DSA:3.60.21.10 119 219 2.1E-12 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS10760 f101fde7dab0c966da130bdbfe5a7982 249 Gene3D G3DSA:3.60.21.10 1 67 2.1E-12 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS10760 f101fde7dab0c966da130bdbfe5a7982 249 Pfam PF00149 Calcineurin-like phosphoesterase 3 213 4.7E-9 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 K08M4_RS04030 ae08b8da52917a3e6d72ab921445e621 308 Pfam PF01584 CheW-like domain 21 155 5.7E-34 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS04030 ae08b8da52917a3e6d72ab921445e621 308 SMART SM00448 182 302 5.5E-20 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS04030 ae08b8da52917a3e6d72ab921445e621 308 SUPERFAMILY SSF52172 183 306 5.69E-26 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS04030 ae08b8da52917a3e6d72ab921445e621 308 Gene3D G3DSA:3.40.50.2300 182 306 1.5E-27 T 05-07-2017 K08M4_RS04030 ae08b8da52917a3e6d72ab921445e621 308 SUPERFAMILY SSF50341 16 156 2.49E-35 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS04030 ae08b8da52917a3e6d72ab921445e621 308 SMART SM00260 17 153 9.3E-25 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS04030 ae08b8da52917a3e6d72ab921445e621 308 Gene3D G3DSA:2.30.30.40 88 146 1.5E-4 T 05-07-2017 K08M4_RS04030 ae08b8da52917a3e6d72ab921445e621 308 Pfam PF00072 Response regulator receiver domain 184 300 9.7E-19 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS04030 ae08b8da52917a3e6d72ab921445e621 308 PIRSF PIRSF002867 1 308 7.1E-103 T 05-07-2017 IPR024181 Chemotaxis response regulator CheV K08M4_RS15855 aafa4f0d056831cd5970eda6cd12ddfb 198 SUPERFAMILY SSF52833 40 196 1.0E-37 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS15855 aafa4f0d056831cd5970eda6cd12ddfb 198 Gene3D G3DSA:3.40.30.10 7 196 5.1E-44 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS15855 aafa4f0d056831cd5970eda6cd12ddfb 198 Pfam PF02630 SCO1/SenC 28 178 4.5E-32 T 05-07-2017 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS08675 da697184191c63d0b54ab80f7c8aa5b3 760 SUPERFAMILY SSF47203 301 453 4.03E-20 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 K08M4_RS08675 da697184191c63d0b54ab80f7c8aa5b3 760 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 178 277 2.2E-10 T 05-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 K08M4_RS08675 da697184191c63d0b54ab80f7c8aa5b3 760 Gene3D G3DSA:1.20.140.10 290 448 8.4E-22 T 05-07-2017 K08M4_RS08675 da697184191c63d0b54ab80f7c8aa5b3 760 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 65 173 3.5E-13 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 K08M4_RS08675 da697184191c63d0b54ab80f7c8aa5b3 760 Pfam PF09317 Domain of unknown function (DUF1974) 455 739 2.7E-111 T 05-07-2017 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 K08M4_RS08675 da697184191c63d0b54ab80f7c8aa5b3 760 Gene3D G3DSA:2.40.110.10 178 289 1.0E-17 T 05-07-2017 K08M4_RS08675 da697184191c63d0b54ab80f7c8aa5b3 760 Gene3D G3DSA:1.10.540.10 37 174 5.4E-25 T 05-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 K08M4_RS08675 da697184191c63d0b54ab80f7c8aa5b3 760 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 301 446 1.0E-9 T 05-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 K08M4_RS08675 da697184191c63d0b54ab80f7c8aa5b3 760 SUPERFAMILY SSF56645 60 296 1.57E-44 T 05-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 K08M4_RS05555 cc03733ce976263146031d5ac6e8ddf1 145 Gene3D G3DSA:3.10.129.10 12 137 8.9E-48 T 05-07-2017 IPR029069 HotDog domain K08M4_RS05555 cc03733ce976263146031d5ac6e8ddf1 145 SUPERFAMILY SSF54637 12 140 1.61E-40 T 05-07-2017 IPR029069 HotDog domain K08M4_RS05555 cc03733ce976263146031d5ac6e8ddf1 145 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 14 137 5.4E-50 T 05-07-2017 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 K08M4_RS05555 cc03733ce976263146031d5ac6e8ddf1 145 Pfam PF03061 Thioesterase superfamily 28 111 2.6E-17 T 05-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 K08M4_RS05555 cc03733ce976263146031d5ac6e8ddf1 145 PIRSF PIRSF003230 6 144 2.0E-47 T 05-07-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 K08M4_RS05555 cc03733ce976263146031d5ac6e8ddf1 145 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 17 133 1.4E-38 T 05-07-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 K08M4_RS00170 543a30915be5e5d9d19058d4efdeacb7 260 Pfam PF00899 ThiF family 10 244 4.3E-58 T 05-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 K08M4_RS00170 543a30915be5e5d9d19058d4efdeacb7 260 Gene3D G3DSA:3.40.50.720 4 248 1.3E-66 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS00170 543a30915be5e5d9d19058d4efdeacb7 260 SUPERFAMILY SSF69572 2 248 1.03E-74 T 05-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 SUPERFAMILY SSF101353 255 462 6.41E-60 T 05-07-2017 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 7 839 0.0 T 05-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 Pfam PF01411 tRNA synthetases class II (A) 7 555 7.7E-227 T 05-07-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 SUPERFAMILY SSF55186 551 716 3.66E-52 T 05-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 Pfam PF02272 DHHA1 domain 786 853 3.5E-16 T 05-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 PRINTS PR00980 Alanyl-tRNA synthetase signature 76 87 1.0E-31 T 05-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 PRINTS PR00980 Alanyl-tRNA synthetase signature 281 297 1.0E-31 T 05-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 PRINTS PR00980 Alanyl-tRNA synthetase signature 208 219 1.0E-31 T 05-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 PRINTS PR00980 Alanyl-tRNA synthetase signature 235 248 1.0E-31 T 05-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 PRINTS PR00980 Alanyl-tRNA synthetase signature 305 318 1.0E-31 T 05-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 SUPERFAMILY SSF50447 454 551 2.9E-18 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 SMART SM00863 652 695 1.1E-21 T 05-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 652 695 3.1E-18 T 05-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 Gene3D G3DSA:3.30.930.10 3 251 1.6E-122 T 05-07-2017 K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 SUPERFAMILY SSF55681 3 254 7.7E-108 T 05-07-2017 K08M4_RS02625 a3cacd5822eec46c057ce980d1eddbe1 860 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 860 196.391 T 05-07-2017 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 Pfam PF02080 TrkA-C domain 156 225 4.1E-11 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 Pfam PF02080 TrkA-C domain 391 450 2.9E-9 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 SUPERFAMILY SSF116726 375 437 4.32E-7 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 SUPERFAMILY SSF51735 1 151 2.36E-35 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 Gene3D G3DSA:3.30.70.1450 391 436 4.5E-4 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 SUPERFAMILY SSF51735 232 376 2.35E-32 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 SUPERFAMILY SSF116726 148 226 2.62E-9 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 Pfam PF02254 TrkA-N domain 235 350 3.5E-24 T 05-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 Pfam PF02254 TrkA-N domain 3 115 4.7E-28 T 05-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 Gene3D G3DSA:3.40.50.720 1 152 1.0E-48 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 Gene3D G3DSA:3.40.50.720 233 376 2.2E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 8.8E-32 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 8.8E-32 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 8.8E-32 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 8.8E-32 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 K08M4_RS14805 9bd7652ac2d9b33c71859ec541db603c 458 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 8.8E-32 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 K08M4_RS09260 5f7d044afd2a1fa2dfde8e02ed47e247 268 SUPERFAMILY SSF51366 1 266 1.51E-91 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 K08M4_RS09260 5f7d044afd2a1fa2dfde8e02ed47e247 268 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 263 1.7E-102 T 05-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 K08M4_RS09260 5f7d044afd2a1fa2dfde8e02ed47e247 268 Pfam PF00290 Tryptophan synthase alpha chain 8 266 4.7E-98 T 05-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 K08M4_RS09260 5f7d044afd2a1fa2dfde8e02ed47e247 268 Gene3D G3DSA:3.20.20.70 1 267 6.7E-96 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS09260 5f7d044afd2a1fa2dfde8e02ed47e247 268 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 05-07-2017 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 K08M4_RS09260 5f7d044afd2a1fa2dfde8e02ed47e247 268 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 265 38.536 T 05-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 K08M4_RS20265 2740e5b3a92de1e808abd4e22a648a42 280 SUPERFAMILY SSF50182 96 169 1.47E-10 T 05-07-2017 IPR010920 LSM domain K08M4_RS20265 2740e5b3a92de1e808abd4e22a648a42 280 Pfam PF00924 Mechanosensitive ion channel 57 184 8.2E-17 T 05-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 K08M4_RS20265 2740e5b3a92de1e808abd4e22a648a42 280 Gene3D G3DSA:2.30.30.60 112 168 2.2E-14 T 05-07-2017 K08M4_RS19320 88ee9079bc7957d5376424159c594c61 810 SUPERFAMILY SSF141868 534 785 9.55E-72 T 05-07-2017 IPR001633 EAL domain K08M4_RS19320 88ee9079bc7957d5376424159c594c61 810 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 348 513 1.7E-15 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS19320 88ee9079bc7957d5376424159c594c61 810 Gene3D G3DSA:3.30.70.270 353 516 3.1E-21 T 05-07-2017 K08M4_RS19320 88ee9079bc7957d5376424159c594c61 810 SMART SM00052 529 775 9.6E-71 T 05-07-2017 IPR001633 EAL domain K08M4_RS19320 88ee9079bc7957d5376424159c594c61 810 SMART SM00267 341 520 9.2E-7 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS19320 88ee9079bc7957d5376424159c594c61 810 Gene3D G3DSA:3.20.20.450 533 783 9.6E-74 T 05-07-2017 IPR001633 EAL domain K08M4_RS19320 88ee9079bc7957d5376424159c594c61 810 Pfam PF00990 Diguanylate cyclase, GGDEF domain 351 510 1.7E-19 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS19320 88ee9079bc7957d5376424159c594c61 810 SUPERFAMILY SSF55073 356 512 2.28E-18 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS19320 88ee9079bc7957d5376424159c594c61 810 Pfam PF00563 EAL domain 536 770 2.9E-58 T 05-07-2017 IPR001633 EAL domain K08M4_RS04385 7cc1589e8bcbf20a8760991b619fa02f 213 Pfam PF01810 LysE type translocator 15 207 1.6E-35 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS04385 7cc1589e8bcbf20a8760991b619fa02f 213 PIRSF PIRSF006324 1 212 1.1E-63 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS00245 0d3aeffddf7cb41a03dd094388077686 220 PIRSF PIRSF006324 1 215 2.3E-50 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS00245 0d3aeffddf7cb41a03dd094388077686 220 Pfam PF01810 LysE type translocator 16 212 9.5E-38 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 Gene3D G3DSA:3.30.413.10 433 562 1.2E-33 T 05-07-2017 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 Gene3D G3DSA:3.30.413.10 152 343 3.2E-71 T 05-07-2017 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 PRINTS PR00397 Sirohaem Fe-binding site signature 433 451 6.5E-9 T 05-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 PRINTS PR00397 Sirohaem Fe-binding site signature 482 500 6.5E-9 T 05-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 SUPERFAMILY SSF55124 349 425 3.93E-20 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 482 498 - T 05-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 SUPERFAMILY SSF56014 432 564 1.05E-31 T 05-07-2017 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 22 563 2.9E-282 T 05-07-2017 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 13 575 57.689 T 05-07-2017 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 176 333 1.5E-46 T 05-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 434 551 6.8E-4 T 05-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 Gene3D G3DSA:3.90.480.10 77 149 2.9E-62 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 Gene3D G3DSA:3.90.480.10 345 426 2.9E-62 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 SUPERFAMILY SSF55124 17 148 2.94E-26 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 SUPERFAMILY SSF56014 152 347 2.49E-60 T 05-07-2017 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 82 141 4.8E-14 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS13365 40b4eaeb28231f59e33223d240afd348 575 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 356 420 5.9E-13 T 05-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 K08M4_RS00165 6feafc05a3c595c567d1dab0ef6af48b 430 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 218 404 1.9E-45 T 05-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS00165 6feafc05a3c595c567d1dab0ef6af48b 430 SUPERFAMILY SSF51391 208 409 3.4E-58 T 05-07-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS00165 6feafc05a3c595c567d1dab0ef6af48b 430 Gene3D G3DSA:3.20.20.70 205 411 2.1E-63 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS00165 6feafc05a3c595c567d1dab0ef6af48b 430 Pfam PF02581 Thiamine monophosphate synthase/TENI 216 394 3.0E-51 T 05-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 SMART SM00304 181 236 2.1E-4 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 SUPERFAMILY SSF47384 220 301 1.73E-14 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 458 6.2E-20 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 SMART SM00387 346 461 1.3E-28 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 300 1.6E-13 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 Gene3D G3DSA:1.10.287.130 230 286 7.5E-15 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 Gene3D G3DSA:3.30.565.10 287 459 1.8E-34 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 SUPERFAMILY SSF55874 291 459 2.23E-35 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 Pfam PF16750 Sensor domain of 2-component histidine kinase 52 152 1.8E-29 T 05-07-2017 IPR031930 2-component histidine kinase, sensor domain K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 458 6.2E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 6.2E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 6.2E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 6.2E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 Pfam PF00672 HAMP domain 166 230 5.0E-11 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 SUPERFAMILY SSF158472 183 233 1.01E-5 T 05-07-2017 K08M4_RS18060 0bbf622521f6150a674934e367e94ec9 461 SMART SM00388 237 301 1.8E-14 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 SMART SM00304 181 236 2.1E-4 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 SUPERFAMILY SSF47384 220 301 1.73E-14 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 458 6.2E-20 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 SMART SM00387 346 461 1.3E-28 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 300 1.6E-13 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 Gene3D G3DSA:1.10.287.130 230 286 7.5E-15 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 Gene3D G3DSA:3.30.565.10 287 459 1.8E-34 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 SUPERFAMILY SSF55874 291 459 2.23E-35 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 Pfam PF16750 Sensor domain of 2-component histidine kinase 52 152 1.8E-29 T 05-07-2017 IPR031930 2-component histidine kinase, sensor domain K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 458 6.2E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 6.2E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 6.2E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 6.2E-12 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 Pfam PF00672 HAMP domain 166 230 5.0E-11 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 SUPERFAMILY SSF158472 183 233 1.01E-5 T 05-07-2017 K08M4_RS18215 0bbf622521f6150a674934e367e94ec9 461 SMART SM00388 237 301 1.8E-14 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS09190 6f220e8e12301759fae7943da8aa0bd4 787 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 415 428 1.6E-10 T 05-07-2017 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS09190 6f220e8e12301759fae7943da8aa0bd4 787 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 544 552 1.6E-10 T 05-07-2017 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS09190 6f220e8e12301759fae7943da8aa0bd4 787 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 492 504 1.6E-10 T 05-07-2017 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS09190 6f220e8e12301759fae7943da8aa0bd4 787 Gene3D G3DSA:3.30.420.10 153 366 7.1E-40 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS09190 6f220e8e12301759fae7943da8aa0bd4 787 Pfam PF03104 DNA polymerase family B, exonuclease domain 71 296 3.2E-19 T 05-07-2017 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS09190 6f220e8e12301759fae7943da8aa0bd4 787 Pfam PF00136 DNA polymerase family B 378 744 1.1E-42 T 05-07-2017 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS09190 6f220e8e12301759fae7943da8aa0bd4 787 SUPERFAMILY SSF56672 385 780 1.22E-115 T 05-07-2017 K08M4_RS09190 6f220e8e12301759fae7943da8aa0bd4 787 ProSitePatterns PS00116 DNA polymerase family B signature. 546 554 - T 05-07-2017 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS09190 6f220e8e12301759fae7943da8aa0bd4 787 SMART SM00486 153 558 5.0E-65 T 05-07-2017 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS09190 6f220e8e12301759fae7943da8aa0bd4 787 SUPERFAMILY SSF53098 4 389 1.2E-83 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS09190 6f220e8e12301759fae7943da8aa0bd4 787 Gene3D G3DSA:3.90.1600.10 401 431 3.2E-10 T 05-07-2017 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS09190 6f220e8e12301759fae7943da8aa0bd4 787 Gene3D G3DSA:3.90.1600.10 515 639 3.2E-10 T 05-07-2017 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS14590 989512ea926ad23a4b0443e746bd3d6a 328 Pfam PF05036 Sporulation related domain 74 143 1.1E-9 T 05-07-2017 IPR007730 Sporulation-related domain GO:0042834 K08M4_RS14590 989512ea926ad23a4b0443e746bd3d6a 328 SUPERFAMILY SSF110997 72 144 6.8E-7 T 05-07-2017 IPR007730 Sporulation-related domain GO:0042834 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 Gene3D G3DSA:3.50.50.60 151 270 4.2E-36 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 7.5E-40 T 05-07-2017 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 279 7.5E-40 T 05-07-2017 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 7.5E-40 T 05-07-2017 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 7.5E-40 T 05-07-2017 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 7.5E-40 T 05-07-2017 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 327 5.0E-63 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 PIRSF PIRSF000350 1 467 7.3E-83 T 05-07-2017 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 SUPERFAMILY SSF51905 1 321 5.94E-58 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 Gene3D G3DSA:3.30.390.30 336 461 1.4E-43 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 Gene3D G3DSA:3.50.50.60 7 148 8.4E-65 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 Gene3D G3DSA:3.50.50.60 271 335 8.4E-65 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 8 459 5.6E-149 T 05-07-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 8.3E-68 T 05-07-2017 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 8.3E-68 T 05-07-2017 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 429 449 8.3E-68 T 05-07-2017 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 8.3E-68 T 05-07-2017 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 8.3E-68 T 05-07-2017 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 8.3E-68 T 05-07-2017 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 264 278 8.3E-68 T 05-07-2017 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 8.3E-68 T 05-07-2017 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 8.3E-68 T 05-07-2017 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 454 7.3E-35 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 42 52 - T 05-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 K08M4_RS02835 171951187dd94046fd9dccddb5e4e124 475 SUPERFAMILY SSF55424 342 465 3.95E-38 T 05-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 K08M4_RS06190 66e5bf202267fca8d8f26c32ea92a594 111 Pfam PF07883 Cupin domain 35 93 8.6E-11 T 05-07-2017 IPR013096 Cupin 2, conserved barrel K08M4_RS06190 66e5bf202267fca8d8f26c32ea92a594 111 Gene3D G3DSA:2.60.120.10 4 110 2.3E-29 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS06190 66e5bf202267fca8d8f26c32ea92a594 111 SUPERFAMILY SSF51182 2 110 8.42E-24 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS06190 66e5bf202267fca8d8f26c32ea92a594 111 PIRSF PIRSF029883 3 111 1.1E-31 T 05-07-2017 IPR025499 Pectin degradation protein KdgF K08M4_RS19410 5cfecf334b3a785e981d37616aff5a80 550 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS19410 5cfecf334b3a785e981d37616aff5a80 550 Pfam PF00005 ABC transporter 42 200 2.1E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS19410 5cfecf334b3a785e981d37616aff5a80 550 Pfam PF00005 ABC transporter 319 469 2.2E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS19410 5cfecf334b3a785e981d37616aff5a80 550 SUPERFAMILY SSF52540 292 540 3.94E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19410 5cfecf334b3a785e981d37616aff5a80 550 SMART SM00382 327 533 1.2E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS19410 5cfecf334b3a785e981d37616aff5a80 550 SMART SM00382 50 250 1.9E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS19410 5cfecf334b3a785e981d37616aff5a80 550 SUPERFAMILY SSF52540 21 272 1.36E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19410 5cfecf334b3a785e981d37616aff5a80 550 Gene3D G3DSA:3.40.50.300 20 274 1.4E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19410 5cfecf334b3a785e981d37616aff5a80 550 Gene3D G3DSA:3.40.50.300 290 541 2.7E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19410 5cfecf334b3a785e981d37616aff5a80 550 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS19410 5cfecf334b3a785e981d37616aff5a80 550 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 252 277 9.9E-5 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS19410 5cfecf334b3a785e981d37616aff5a80 550 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 520 542 0.0092 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 Pfam PF11741 AMIN domain 34 136 4.8E-18 T 05-07-2017 IPR021731 AMIN domain K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 Gene3D G3DSA:3.40.630.40 168 265 7.7E-56 T 05-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 Gene3D G3DSA:3.40.630.40 317 393 7.7E-56 T 05-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 SUPERFAMILY SSF54106 414 457 2.22E-10 T 05-07-2017 IPR018392 LysM domain K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 SUPERFAMILY SSF54106 526 569 3.27E-10 T 05-07-2017 IPR018392 LysM domain K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 SUPERFAMILY SSF53187 316 392 1.0E-51 T 05-07-2017 K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 SUPERFAMILY SSF53187 168 264 1.0E-51 T 05-07-2017 K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 SMART SM00257 526 569 8.1E-13 T 05-07-2017 IPR018392 LysM domain K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 SMART SM00257 414 457 3.8E-15 T 05-07-2017 IPR018392 LysM domain K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 SMART SM00257 473 516 1.4E-12 T 05-07-2017 IPR018392 LysM domain K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 170 389 1.7E-49 T 05-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 Gene3D G3DSA:3.10.350.10 470 516 5.4E-16 T 05-07-2017 IPR018392 LysM domain K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 Gene3D G3DSA:3.10.350.10 415 458 1.5E-16 T 05-07-2017 IPR018392 LysM domain K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 Gene3D G3DSA:3.10.350.10 526 569 7.0E-16 T 05-07-2017 IPR018392 LysM domain K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 SMART SM00646 230 389 1.1E-61 T 05-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 SUPERFAMILY SSF54106 472 516 1.29E-9 T 05-07-2017 IPR018392 LysM domain K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 Pfam PF01476 LysM domain 415 457 1.3E-13 T 05-07-2017 IPR018392 LysM domain K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 Pfam PF01476 LysM domain 474 515 1.9E-11 T 05-07-2017 IPR018392 LysM domain K08M4_RS13540 565c3059734d8332e9ed777566964af4 571 Pfam PF01476 LysM domain 527 569 5.6E-13 T 05-07-2017 IPR018392 LysM domain K08M4_RS06200 36d89726bc969cdf5cd66cbc717d9677 717 Pfam PF07940 Heparinase II/III-like protein 356 630 1.7E-21 T 05-07-2017 IPR012480 Heparinase II/III-like GO:0016829 K08M4_RS06200 36d89726bc969cdf5cd66cbc717d9677 717 Gene3D G3DSA:1.50.10.110 55 329 2.0E-33 T 05-07-2017 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 K08M4_RS06200 36d89726bc969cdf5cd66cbc717d9677 717 Pfam PF05426 Alginate lyase 48 264 1.8E-13 T 05-07-2017 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 K08M4_RS06200 36d89726bc969cdf5cd66cbc717d9677 717 SUPERFAMILY SSF48230 31 327 2.29E-47 T 05-07-2017 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 K08M4_RS06460 ada33dc3e1d4ba89f71edff4c0ee466d 333 SUPERFAMILY SSF52540 12 203 8.65E-25 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06460 ada33dc3e1d4ba89f71edff4c0ee466d 333 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 12 187 1.6E-41 T 05-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain K08M4_RS06460 ada33dc3e1d4ba89f71edff4c0ee466d 333 Gene3D G3DSA:3.40.50.300 11 206 2.0E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01510 698a764d09b538c1a04abfa042def6bb 84 Pfam PF00366 Ribosomal protein S17 10 77 2.4E-33 T 05-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01510 698a764d09b538c1a04abfa042def6bb 84 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 6 76 2.9E-37 T 05-07-2017 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01510 698a764d09b538c1a04abfa042def6bb 84 ProSitePatterns PS00056 Ribosomal protein S17 signature. 56 68 - T 05-07-2017 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01510 698a764d09b538c1a04abfa042def6bb 84 Gene3D G3DSA:2.40.50.140 5 82 6.2E-37 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS01510 698a764d09b538c1a04abfa042def6bb 84 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 3 81 25.894 T 05-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01510 698a764d09b538c1a04abfa042def6bb 84 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 1 76 3.0E-32 T 05-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01510 698a764d09b538c1a04abfa042def6bb 84 PRINTS PR00973 Ribosomal protein S17 family signature 56 66 2.0E-14 T 05-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01510 698a764d09b538c1a04abfa042def6bb 84 PRINTS PR00973 Ribosomal protein S17 family signature 24 47 2.0E-14 T 05-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01510 698a764d09b538c1a04abfa042def6bb 84 PRINTS PR00973 Ribosomal protein S17 family signature 66 73 2.0E-14 T 05-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01510 698a764d09b538c1a04abfa042def6bb 84 SUPERFAMILY SSF50249 6 83 3.0E-33 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS11890 a15d24ff830810bc14c0736cb1053bd8 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 05-07-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site K08M4_RS11890 a15d24ff830810bc14c0736cb1053bd8 107 SUPERFAMILY SSF89360 1 96 7.19E-35 T 05-07-2017 IPR000361 FeS cluster biogenesis K08M4_RS11890 a15d24ff830810bc14c0736cb1053bd8 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 1.9E-57 T 05-07-2017 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0016226|GO:0051536 K08M4_RS11890 a15d24ff830810bc14c0736cb1053bd8 107 Gene3D G3DSA:2.60.300.12 2 96 1.0E-36 T 05-07-2017 IPR000361 FeS cluster biogenesis K08M4_RS11890 a15d24ff830810bc14c0736cb1053bd8 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 3.7E-27 T 05-07-2017 IPR000361 FeS cluster biogenesis K08M4_RS11890 a15d24ff830810bc14c0736cb1053bd8 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 2.4E-38 T 05-07-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 K08M4_RS11890 a15d24ff830810bc14c0736cb1053bd8 107 TIGRFAM TIGR01997 sufA_proteo: FeS assembly scaffold SufA 2 107 6.4E-42 T 05-07-2017 IPR011298 FeS assembly scaffold SufA GO:0016226 K08M4_RS20795 8af4e588b81a0f2b802b5b3f864e184b 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 3.4E-21 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS20795 8af4e588b81a0f2b802b5b3f864e184b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 3.1E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS20795 8af4e588b81a0f2b802b5b3f864e184b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 3.1E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS20795 8af4e588b81a0f2b802b5b3f864e184b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 3.1E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS20795 8af4e588b81a0f2b802b5b3f864e184b 301 Gene3D G3DSA:3.40.190.10 181 263 7.6E-6 T 05-07-2017 K08M4_RS20795 8af4e588b81a0f2b802b5b3f864e184b 301 Gene3D G3DSA:3.40.190.10 111 180 1.6E-19 T 05-07-2017 K08M4_RS20795 8af4e588b81a0f2b802b5b3f864e184b 301 SUPERFAMILY SSF46785 6 85 2.86E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20795 8af4e588b81a0f2b802b5b3f864e184b 301 Gene3D G3DSA:1.10.10.10 5 85 1.6E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20795 8af4e588b81a0f2b802b5b3f864e184b 301 SUPERFAMILY SSF53850 93 300 2.64E-41 T 05-07-2017 K08M4_RS20795 8af4e588b81a0f2b802b5b3f864e184b 301 Pfam PF03466 LysR substrate binding domain 92 294 6.1E-39 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS16710 3e3f4f7154ca9dd57de5be03eb8bf2cb 210 Pfam PF01810 LysE type translocator 16 204 2.0E-28 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS16710 3e3f4f7154ca9dd57de5be03eb8bf2cb 210 PIRSF PIRSF006324 1 208 1.4E-55 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS05740 d2f910c2fd9ab93b55bf830cf9970477 206 Pfam PF04279 Intracellular septation protein A 1 174 1.5E-67 T 05-07-2017 IPR006008 Intracellular septation protein A GO:0016021 K08M4_RS05740 d2f910c2fd9ab93b55bf830cf9970477 206 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 1 176 2.2E-66 T 05-07-2017 IPR006008 Intracellular septation protein A GO:0016021 K08M4_RS05740 d2f910c2fd9ab93b55bf830cf9970477 206 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 175 18.703 T 05-07-2017 IPR006008 Intracellular septation protein A GO:0016021 K08M4_RS07000 ca15139bae9bfb152644b8fd6de052f0 314 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 288 1.7E-46 T 05-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 K08M4_RS07000 ca15139bae9bfb152644b8fd6de052f0 314 SUPERFAMILY SSF52283 2 123 6.8E-19 T 05-07-2017 K08M4_RS07000 ca15139bae9bfb152644b8fd6de052f0 314 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 17 309 9.1E-13 T 05-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 K08M4_RS07000 ca15139bae9bfb152644b8fd6de052f0 314 Gene3D G3DSA:3.40.50.720 2 112 5.3E-22 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS07000 ca15139bae9bfb152644b8fd6de052f0 314 Gene3D G3DSA:3.40.50.720 113 289 2.0E-50 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS07000 ca15139bae9bfb152644b8fd6de052f0 314 SUPERFAMILY SSF51735 105 288 2.99E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS18530 a9fbc0acf5f26b8152a9bcc813f55b4f 50 Pfam PF03701 Uncharacterised protein family (UPF0181) 1 49 1.1E-25 T 05-07-2017 IPR005371 Uncharacterised protein family UPF0181 K08M4_RS18530 a9fbc0acf5f26b8152a9bcc813f55b4f 50 ProDom PD026807 UPF0181 YOAH YPTB1650 VV20310 VPA0916 VCA0569 YPO1774/Y2534/YP1619 PLU2693 VVA0806 PM0480 1 48 2.0E-12 T 05-07-2017 IPR005371 Uncharacterised protein family UPF0181 K08M4_RS08905 c96a39046a23a6bc46ef590433d22ec5 323 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 9 323 3.4E-146 T 05-07-2017 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 K08M4_RS08905 c96a39046a23a6bc46ef590433d22ec5 323 PIRSF PIRSF000355 1 320 7.4E-87 T 05-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS08905 c96a39046a23a6bc46ef590433d22ec5 323 Pfam PF00268 Ribonucleotide reductase, small chain 12 284 1.2E-86 T 05-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS08905 c96a39046a23a6bc46ef590433d22ec5 323 SUPERFAMILY SSF47240 7 323 2.84E-103 T 05-07-2017 IPR009078 Ferritin-like superfamily K08M4_RS08905 c96a39046a23a6bc46ef590433d22ec5 323 Gene3D G3DSA:1.10.620.20 6 284 1.6E-90 T 05-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 K08M4_RS08905 c96a39046a23a6bc46ef590433d22ec5 323 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 100 116 - T 05-07-2017 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS05310 bb06ca3f6b66b62fe11cb95a90bbd115 705 SUPERFAMILY SSF58104 396 705 1.02E-73 T 05-07-2017 K08M4_RS05310 bb06ca3f6b66b62fe11cb95a90bbd115 705 SMART SM00283 443 704 3.8E-64 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS05310 bb06ca3f6b66b62fe11cb95a90bbd115 705 Gene3D G3DSA:1.10.287.950 458 673 2.9E-54 T 05-07-2017 K08M4_RS05310 bb06ca3f6b66b62fe11cb95a90bbd115 705 Gene3D G3DSA:3.30.450.20 211 339 8.5E-8 T 05-07-2017 K08M4_RS05310 bb06ca3f6b66b62fe11cb95a90bbd115 705 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 492 702 3.1E-46 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS05310 bb06ca3f6b66b62fe11cb95a90bbd115 705 Pfam PF02743 Cache domain 48 324 1.1E-17 T 05-07-2017 IPR033479 Double Cache domain 1 K08M4_RS05310 bb06ca3f6b66b62fe11cb95a90bbd115 705 SMART SM00304 374 428 5.8E-15 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS05310 bb06ca3f6b66b62fe11cb95a90bbd115 705 Pfam PF00672 HAMP domain 356 425 9.6E-15 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 Pfam PF01926 50S ribosome-binding GTPase 217 306 7.7E-24 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 453 32.874 T 05-07-2017 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 Gene3D G3DSA:3.40.50.300 193 245 4.1E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 Gene3D G3DSA:1.20.120.430 383 453 8.9E-60 T 05-07-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 Gene3D G3DSA:1.20.120.430 246 270 8.9E-60 T 05-07-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 Gene3D G3DSA:1.20.120.430 121 181 8.9E-60 T 05-07-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 SUPERFAMILY SSF116878 120 219 1.44E-52 T 05-07-2017 K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 SUPERFAMILY SSF116878 378 453 1.44E-52 T 05-07-2017 K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 SUPERFAMILY SSF52540 70 151 4.51E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 SUPERFAMILY SSF52540 187 371 4.51E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 Gene3D G3DSA:3.30.1360.120 2 120 5.8E-42 T 05-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 215 368 6.7E-22 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 Gene3D G3DSA:3.40.50.300 285 374 4.8E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 10 453 1.4E-99 T 05-07-2017 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 Pfam PF12631 MnmE helical domain 122 450 2.4E-61 T 05-07-2017 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 K08M4_RS14980 7041012d0b0baf7c41f43a9600e94432 453 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 119 1.9E-34 T 05-07-2017 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 K08M4_RS21265 9c993f41556950cfacff26af54407f2c 335 Gene3D G3DSA:3.40.50.2300 166 328 1.2E-55 T 05-07-2017 K08M4_RS21265 9c993f41556950cfacff26af54407f2c 335 Pfam PF13377 Periplasmic binding protein-like domain 168 328 3.3E-36 T 05-07-2017 K08M4_RS21265 9c993f41556950cfacff26af54407f2c 335 SUPERFAMILY SSF47413 2 59 5.89E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS21265 9c993f41556950cfacff26af54407f2c 335 Gene3D G3DSA:3.40.50.2300 58 165 1.2E-41 T 05-07-2017 K08M4_RS21265 9c993f41556950cfacff26af54407f2c 335 Gene3D G3DSA:1.10.260.40 2 57 1.2E-23 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS21265 9c993f41556950cfacff26af54407f2c 335 SMART SM00354 1 71 1.1E-26 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS21265 9c993f41556950cfacff26af54407f2c 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 8.7E-18 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS21265 9c993f41556950cfacff26af54407f2c 335 SUPERFAMILY SSF53822 61 330 1.3E-82 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS02375 663ef9ec4aba0ae768f64640e4292ac7 102 Pfam PF05164 Cell division protein ZapA 6 88 3.6E-19 T 05-07-2017 IPR007838 Cell division protein ZapA-like K08M4_RS02375 663ef9ec4aba0ae768f64640e4292ac7 102 SUPERFAMILY SSF102829 6 95 2.88E-23 T 05-07-2017 IPR007838 Cell division protein ZapA-like K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 SUPERFAMILY SSF52518 243 381 1.6E-77 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 SUPERFAMILY SSF52518 9 199 1.6E-77 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 Pfam PF02779 Transketolase, pyrimidine binding domain 318 479 3.6E-37 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 Pfam PF02780 Transketolase, C-terminal domain 505 617 1.1E-26 T 05-07-2017 IPR033248 Transketolase, C-terminal domain K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 10 626 45.908 T 05-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 Gene3D G3DSA:3.40.50.970 335 495 5.5E-36 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 SMART SM00861 319 483 1.6E-63 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 SUPERFAMILY SSF52518 317 504 7.12E-58 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 12 625 2.1E-300 T 05-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 SUPERFAMILY SSF52922 492 625 1.09E-29 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 ProSitePatterns PS00802 Transketolase signature 2. 425 441 - T 05-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 Gene3D G3DSA:3.40.50.920 496 625 9.2E-35 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 ProSitePatterns PS00801 Transketolase signature 1. 36 55 - T 05-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 Gene3D G3DSA:3.40.50.970 26 201 9.2E-76 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 Gene3D G3DSA:3.40.50.970 242 334 9.2E-76 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS03530 5a78ba153863b43ac7dbbde8445ba478 627 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 14 282 2.0E-121 T 05-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS03330 6e55987c54001ca8361f2542bfa89bec 251 Pfam PF12833 Helix-turn-helix domain 162 241 6.5E-20 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS03330 6e55987c54001ca8361f2542bfa89bec 251 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 209 224 1.2E-7 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS03330 6e55987c54001ca8361f2542bfa89bec 251 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 224 240 1.2E-7 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS03330 6e55987c54001ca8361f2542bfa89bec 251 SUPERFAMILY SSF46689 144 189 3.85E-5 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS03330 6e55987c54001ca8361f2542bfa89bec 251 Gene3D G3DSA:1.10.10.60 144 191 2.2E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS03330 6e55987c54001ca8361f2542bfa89bec 251 Gene3D G3DSA:1.10.10.60 193 242 4.3E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS03330 6e55987c54001ca8361f2542bfa89bec 251 SMART SM00342 156 240 2.5E-26 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS03330 6e55987c54001ca8361f2542bfa89bec 251 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 193 236 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 K08M4_RS03330 6e55987c54001ca8361f2542bfa89bec 251 SUPERFAMILY SSF46689 193 243 2.6E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS01795 44c4a24dcddaf9fa516a0fde48e58fc0 289 Pfam PF03668 P-loop ATPase protein family 1 285 2.5E-109 T 05-07-2017 IPR005337 RapZ-like family GO:0005524 K08M4_RS01795 44c4a24dcddaf9fa516a0fde48e58fc0 289 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 285 40.151 T 05-07-2017 IPR005337 RapZ-like family GO:0005524 K08M4_RS01795 44c4a24dcddaf9fa516a0fde48e58fc0 289 SUPERFAMILY SSF52540 1 153 4.67E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01795 44c4a24dcddaf9fa516a0fde48e58fc0 289 Gene3D G3DSA:3.40.50.300 1 157 2.2E-15 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01795 44c4a24dcddaf9fa516a0fde48e58fc0 289 PIRSF PIRSF005052 1 288 4.5E-105 T 05-07-2017 IPR005337 RapZ-like family GO:0005524 K08M4_RS04865 f26346c5d857c7565677ab4ca23faeb0 209 SMART SM00900 100 192 4.5E-36 T 05-07-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 K08M4_RS04865 f26346c5d857c7565677ab4ca23faeb0 209 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 2 194 26.779 T 05-07-2017 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 K08M4_RS04865 f26346c5d857c7565677ab4ca23faeb0 209 PIRSF PIRSF006091 1 205 9.2E-79 T 05-07-2017 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 K08M4_RS04865 f26346c5d857c7565677ab4ca23faeb0 209 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 9 193 7.3E-66 T 05-07-2017 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 K08M4_RS04865 f26346c5d857c7565677ab4ca23faeb0 209 Pfam PF04205 FMN-binding domain 100 189 7.8E-20 T 05-07-2017 IPR007329 FMN-binding GO:0010181|GO:0016020 K08M4_RS08815 9666aeb99f28a93fac940e611e89fcf9 124 SUPERFAMILY SSF54593 3 122 1.17E-19 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS08815 9666aeb99f28a93fac940e611e89fcf9 124 Gene3D G3DSA:3.10.180.10 3 120 1.2E-28 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS08815 9666aeb99f28a93fac940e611e89fcf9 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 118 1.8E-8 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain K08M4_RS20945 c18733a7f300f307e138a5c7b1048c57 147 SUPERFAMILY SSF46785 11 143 5.04E-36 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20945 c18733a7f300f307e138a5c7b1048c57 147 Pfam PF01047 MarR family 40 97 1.3E-14 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS20945 c18733a7f300f307e138a5c7b1048c57 147 Gene3D G3DSA:1.10.10.10 4 146 8.2E-45 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20945 c18733a7f300f307e138a5c7b1048c57 147 SMART SM00347 33 131 1.4E-21 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS01725 b4fe6b349df1dcfd7fd2c370bf9d7a49 209 SUPERFAMILY SSF55068 3 207 8.11E-79 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS01725 b4fe6b349df1dcfd7fd2c370bf9d7a49 209 Pfam PF01625 Peptide methionine sulfoxide reductase 45 197 1.4E-67 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS01725 b4fe6b349df1dcfd7fd2c370bf9d7a49 209 Gene3D G3DSA:3.30.1060.10 3 197 3.7E-80 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS01725 b4fe6b349df1dcfd7fd2c370bf9d7a49 209 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 42 203 37.228 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS01725 b4fe6b349df1dcfd7fd2c370bf9d7a49 209 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 44 197 7.5E-65 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS06525 026f92757e897e68711a5a58f8f4533b 173 Pfam PF09831 Uncharacterized protein conserved in bacteria (DUF2058) 5 173 8.2E-59 T 05-07-2017 IPR018636 Protein of unknown function DUF2058 K08M4_RS09990 9b82d00bb5c8ac1557c7e39f2f08c0cf 303 Gene3D G3DSA:3.40.190.10 88 183 3.8E-5 T 05-07-2017 K08M4_RS09990 9b82d00bb5c8ac1557c7e39f2f08c0cf 303 Pfam PF03466 LysR substrate binding domain 92 299 1.9E-19 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS09990 9b82d00bb5c8ac1557c7e39f2f08c0cf 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 2.3E-12 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS09990 9b82d00bb5c8ac1557c7e39f2f08c0cf 303 Gene3D G3DSA:1.10.10.10 6 87 3.3E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS09990 9b82d00bb5c8ac1557c7e39f2f08c0cf 303 SUPERFAMILY SSF53850 92 301 6.37E-21 T 05-07-2017 K08M4_RS09990 9b82d00bb5c8ac1557c7e39f2f08c0cf 303 SUPERFAMILY SSF46785 6 83 1.69E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS09990 9b82d00bb5c8ac1557c7e39f2f08c0cf 303 Gene3D G3DSA:3.40.190.10 184 266 2.8E-7 T 05-07-2017 K08M4_RS17305 a0521cc8332a5ce40c6cf14ce01e6099 767 Gene3D G3DSA:3.20.20.450 505 753 1.1E-86 T 05-07-2017 IPR001633 EAL domain K08M4_RS17305 a0521cc8332a5ce40c6cf14ce01e6099 767 Pfam PF00563 EAL domain 508 742 1.1E-66 T 05-07-2017 IPR001633 EAL domain K08M4_RS17305 a0521cc8332a5ce40c6cf14ce01e6099 767 Pfam PF00990 Diguanylate cyclase, GGDEF domain 336 487 5.6E-40 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS17305 a0521cc8332a5ce40c6cf14ce01e6099 767 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 335 489 5.6E-33 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS17305 a0521cc8332a5ce40c6cf14ce01e6099 767 Gene3D G3DSA:3.30.450.20 84 180 9.6E-4 T 05-07-2017 K08M4_RS17305 a0521cc8332a5ce40c6cf14ce01e6099 767 SUPERFAMILY SSF55073 341 492 8.63E-40 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS17305 a0521cc8332a5ce40c6cf14ce01e6099 767 SMART SM00267 325 492 1.9E-48 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS17305 a0521cc8332a5ce40c6cf14ce01e6099 767 Gene3D G3DSA:3.30.70.270 337 498 6.6E-46 T 05-07-2017 K08M4_RS17305 a0521cc8332a5ce40c6cf14ce01e6099 767 SMART SM00052 502 747 3.4E-98 T 05-07-2017 IPR001633 EAL domain K08M4_RS17305 a0521cc8332a5ce40c6cf14ce01e6099 767 SUPERFAMILY SSF141868 507 754 3.79E-82 T 05-07-2017 IPR001633 EAL domain K08M4_RS17880 b23d3605d5495d3fcb49cb1c83a353c2 311 PIRSF PIRSF006230 1 277 3.9E-106 T 05-07-2017 IPR016478 GTPase, MTG1 K08M4_RS17880 b23d3605d5495d3fcb49cb1c83a353c2 311 SUPERFAMILY SSF52540 9 184 1.18E-39 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17880 b23d3605d5495d3fcb49cb1c83a353c2 311 Gene3D G3DSA:3.40.50.300 16 171 7.0E-34 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17880 b23d3605d5495d3fcb49cb1c83a353c2 311 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 272 3.2E-107 T 05-07-2017 IPR019991 GTP-binding protein, ribosome biogenesis K08M4_RS17880 b23d3605d5495d3fcb49cb1c83a353c2 311 Pfam PF01926 50S ribosome-binding GTPase 117 181 3.1E-13 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS17880 b23d3605d5495d3fcb49cb1c83a353c2 311 Gene3D G3DSA:1.10.1580.10 174 266 2.1E-34 T 05-07-2017 IPR023179 GTP-binding protein, orthogonal bundle domain K08M4_RS04560 6eaaa3db8858a95789dfd65d746cd402 308 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 281 36.925 T 05-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS04560 6eaaa3db8858a95789dfd65d746cd402 308 Gene3D G3DSA:3.90.226.10 20 282 2.2E-70 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS04560 6eaaa3db8858a95789dfd65d746cd402 308 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 181 2.4E-38 T 05-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS04560 6eaaa3db8858a95789dfd65d746cd402 308 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 251 260 2.4E-38 T 05-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS04560 6eaaa3db8858a95789dfd65d746cd402 308 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 143 2.4E-38 T 05-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS04560 6eaaa3db8858a95789dfd65d746cd402 308 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 200 217 2.4E-38 T 05-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS04560 6eaaa3db8858a95789dfd65d746cd402 308 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 229 240 2.4E-38 T 05-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS04560 6eaaa3db8858a95789dfd65d746cd402 308 SUPERFAMILY SSF52096 25 283 1.26E-83 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS04560 6eaaa3db8858a95789dfd65d746cd402 308 Pfam PF01039 Carboxyl transferase domain 97 240 1.7E-13 T 05-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 K08M4_RS04560 6eaaa3db8858a95789dfd65d746cd402 308 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 284 9.7E-138 T 05-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS10905 c6cb9898c5fc4cfa4868e25352030475 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 7.1E-28 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS10905 c6cb9898c5fc4cfa4868e25352030475 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.3E-18 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS10905 c6cb9898c5fc4cfa4868e25352030475 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.3E-18 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS10905 c6cb9898c5fc4cfa4868e25352030475 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.3E-18 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS10905 c6cb9898c5fc4cfa4868e25352030475 85 Gene3D G3DSA:3.30.1340.10 1 83 2.1E-32 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS10905 c6cb9898c5fc4cfa4868e25352030475 85 SUPERFAMILY SSF55594 1 82 1.15E-26 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS10905 c6cb9898c5fc4cfa4868e25352030475 85 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 05-07-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site K08M4_RS10905 c6cb9898c5fc4cfa4868e25352030475 85 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 05-07-2017 IPR002114 Phosphotransferase system, HPr serine phosphorylation site K08M4_RS10905 c6cb9898c5fc4cfa4868e25352030475 85 Pfam PF00381 PTS HPr component phosphorylation site 3 82 9.4E-27 T 05-07-2017 IPR000032 Phosphocarrier protein HPr-like K08M4_RS11515 c9b3ebff2dbfa2b36233f090a4ee75c6 182 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 57 74 - T 05-07-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 K08M4_RS11515 c9b3ebff2dbfa2b36233f090a4ee75c6 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 36 51 1.1E-10 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS11515 c9b3ebff2dbfa2b36233f090a4ee75c6 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 136 151 1.1E-10 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS11515 c9b3ebff2dbfa2b36233f090a4ee75c6 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 62 74 1.1E-10 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS11515 c9b3ebff2dbfa2b36233f090a4ee75c6 182 Gene3D G3DSA:2.40.100.10 21 181 6.4E-49 T 05-07-2017 IPR029000 Cyclophilin-like domain K08M4_RS11515 c9b3ebff2dbfa2b36233f090a4ee75c6 182 SUPERFAMILY SSF50891 19 181 2.05E-52 T 05-07-2017 IPR029000 Cyclophilin-like domain K08M4_RS11515 c9b3ebff2dbfa2b36233f090a4ee75c6 182 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 23 179 7.6E-43 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS19775 36e83d84e6976e41e1d27e3c05a8e716 222 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 216 1.1E-40 T 05-07-2017 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 K08M4_RS19775 36e83d84e6976e41e1d27e3c05a8e716 222 Pfam PF03070 TENA/THI-4/PQQC family 9 217 2.1E-43 T 05-07-2017 IPR004305 Thiaminase-2/PQQC K08M4_RS19775 36e83d84e6976e41e1d27e3c05a8e716 222 Gene3D G3DSA:1.20.910.10 4 218 2.5E-71 T 05-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 K08M4_RS19775 36e83d84e6976e41e1d27e3c05a8e716 222 SUPERFAMILY SSF48613 3 216 9.83E-66 T 05-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 K08M4_RS13225 ef6ca66d9320052c56c82d0fa44ed431 379 SUPERFAMILY SSF53383 16 378 1.71E-101 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS13225 ef6ca66d9320052c56c82d0fa44ed431 379 Gene3D G3DSA:3.40.640.10 30 274 7.8E-57 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS13225 ef6ca66d9320052c56c82d0fa44ed431 379 Pfam PF00266 Aminotransferase class-V 20 358 1.7E-33 T 05-07-2017 IPR000192 Aminotransferase class V domain K08M4_RS13225 ef6ca66d9320052c56c82d0fa44ed431 379 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 196 216 - T 05-07-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site K08M4_RS13225 ef6ca66d9320052c56c82d0fa44ed431 379 Gene3D G3DSA:3.90.1150.10 275 378 7.3E-37 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS13225 ef6ca66d9320052c56c82d0fa44ed431 379 PIRSF PIRSF000524 13 379 2.6E-111 T 05-07-2017 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 K08M4_RS20810 877dacebaf6e7abbb15064df10e3be5a 310 Gene3D G3DSA:3.40.190.10 109 241 3.3E-34 T 05-07-2017 K08M4_RS20810 877dacebaf6e7abbb15064df10e3be5a 310 Pfam PF16868 NMT1-like family 27 305 3.3E-77 T 05-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family K08M4_RS20810 877dacebaf6e7abbb15064df10e3be5a 310 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 12 307 3.2E-81 T 05-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family K08M4_RS20810 877dacebaf6e7abbb15064df10e3be5a 310 SUPERFAMILY SSF53850 23 306 1.82E-64 T 05-07-2017 K08M4_RS20810 877dacebaf6e7abbb15064df10e3be5a 310 Gene3D G3DSA:3.40.190.10 242 306 1.6E-46 T 05-07-2017 K08M4_RS20810 877dacebaf6e7abbb15064df10e3be5a 310 Gene3D G3DSA:3.40.190.10 23 103 1.6E-46 T 05-07-2017 K08M4_RS04985 812903ecc63ee686c4f8216ea1f3df12 721 Gene3D G3DSA:3.40.1390.20 226 364 1.3E-27 T 05-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like K08M4_RS04985 812903ecc63ee686c4f8216ea1f3df12 721 Pfam PF13500 AAA domain 3 229 5.9E-49 T 05-07-2017 K08M4_RS04985 812903ecc63ee686c4f8216ea1f3df12 721 Gene3D G3DSA:3.40.50.10750 524 682 6.4E-68 T 05-07-2017 K08M4_RS04985 812903ecc63ee686c4f8216ea1f3df12 721 Pfam PF01515 Phosphate acetyl/butaryl transferase 391 706 4.7E-125 T 05-07-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 K08M4_RS04985 812903ecc63ee686c4f8216ea1f3df12 721 SUPERFAMILY SSF52540 1 240 2.34E-28 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04985 812903ecc63ee686c4f8216ea1f3df12 721 Pfam PF07085 DRTGG domain 233 344 9.5E-28 T 05-07-2017 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 K08M4_RS04985 812903ecc63ee686c4f8216ea1f3df12 721 SUPERFAMILY SSF75138 229 353 4.9E-24 T 05-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like K08M4_RS04985 812903ecc63ee686c4f8216ea1f3df12 721 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 406 706 4.9E-131 T 05-07-2017 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 K08M4_RS04985 812903ecc63ee686c4f8216ea1f3df12 721 Gene3D G3DSA:3.40.50.300 2 223 2.6E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04985 812903ecc63ee686c4f8216ea1f3df12 721 SUPERFAMILY SSF53659 392 709 6.58E-95 T 05-07-2017 K08M4_RS04985 812903ecc63ee686c4f8216ea1f3df12 721 PIRSF PIRSF006107 1 714 0.0 T 05-07-2017 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 K08M4_RS18985 d97d77713afe52ad6222963ef5d0cb3f 964 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 22 956 0.0 T 05-07-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 K08M4_RS18985 d97d77713afe52ad6222963ef5d0cb3f 964 SUPERFAMILY SSF53383 22 448 6.4E-101 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS18985 d97d77713afe52ad6222963ef5d0cb3f 964 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 13 962 25.462 T 05-07-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 K08M4_RS18985 d97d77713afe52ad6222963ef5d0cb3f 964 SUPERFAMILY SSF53383 935 957 4.13E-97 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS18985 d97d77713afe52ad6222963ef5d0cb3f 964 SUPERFAMILY SSF53383 460 892 4.13E-97 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS18985 d97d77713afe52ad6222963ef5d0cb3f 964 Gene3D G3DSA:3.40.640.10 91 320 1.0E-12 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS18985 d97d77713afe52ad6222963ef5d0cb3f 964 Gene3D G3DSA:3.40.640.10 510 745 1.7E-37 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS18985 d97d77713afe52ad6222963ef5d0cb3f 964 Pfam PF02347 Glycine cleavage system P-protein 467 744 1.5E-9 T 05-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 K08M4_RS18985 d97d77713afe52ad6222963ef5d0cb3f 964 Pfam PF02347 Glycine cleavage system P-protein 22 448 3.3E-181 T 05-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 K08M4_RS08080 1861612264a7d182d23b4eb89b99a7a0 244 SUPERFAMILY SSF100950 3 243 3.45E-58 T 05-07-2017 K08M4_RS08080 1861612264a7d182d23b4eb89b99a7a0 244 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 13 242 1.0E-50 T 05-07-2017 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 K08M4_RS08080 1861612264a7d182d23b4eb89b99a7a0 244 Gene3D G3DSA:3.40.50.1360 3 243 5.1E-70 T 05-07-2017 K08M4_RS08080 1861612264a7d182d23b4eb89b99a7a0 244 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 13 233 2.2E-58 T 05-07-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 K08M4_RS21730 05a3f4a62504aa5b545f266043a68ab0 432 Pfam PF02687 FtsX-like permease family 300 422 7.4E-17 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 K08M4_RS21730 05a3f4a62504aa5b545f266043a68ab0 432 Pfam PF12704 MacB-like periplasmic core domain 31 258 8.9E-16 T 05-07-2017 IPR025857 MacB-like periplasmic core domain K08M4_RS18640 a6ba5795ca69b0347048dc170fe05313 551 Pfam PF09818 Predicted ATPase of the ABC class 1 434 1.5E-180 T 05-07-2017 IPR019195 ABC transporter, ATPase, putative K08M4_RS18640 a6ba5795ca69b0347048dc170fe05313 551 SUPERFAMILY SSF52540 226 410 1.88E-7 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18640 a6ba5795ca69b0347048dc170fe05313 551 Gene3D G3DSA:3.40.50.300 230 426 2.2E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15940 445fdd29b13a166fd324ed5c9c3bad36 324 SUPERFAMILY SSF141523 112 250 1.57E-29 T 05-07-2017 K08M4_RS15940 445fdd29b13a166fd324ed5c9c3bad36 324 Gene3D G3DSA:2.40.440.10 107 251 6.9E-36 T 05-07-2017 K08M4_RS15940 445fdd29b13a166fd324ed5c9c3bad36 324 Pfam PF01476 LysM domain 60 103 3.8E-5 T 05-07-2017 IPR018392 LysM domain K08M4_RS15940 445fdd29b13a166fd324ed5c9c3bad36 324 SUPERFAMILY SSF54106 58 103 6.41E-6 T 05-07-2017 IPR018392 LysM domain K08M4_RS15940 445fdd29b13a166fd324ed5c9c3bad36 324 SMART SM00257 59 103 2.0E-4 T 05-07-2017 IPR018392 LysM domain K08M4_RS15940 445fdd29b13a166fd324ed5c9c3bad36 324 Pfam PF03734 L,D-transpeptidase catalytic domain 114 250 1.7E-21 T 05-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 K08M4_RS15940 445fdd29b13a166fd324ed5c9c3bad36 324 Gene3D G3DSA:3.10.350.10 59 103 8.0E-6 T 05-07-2017 IPR018392 LysM domain K08M4_RS18280 632a3c3116c5b7e8775f491a861219d2 278 Pfam PF10670 Domain of unknown function (DUF4198) 26 253 1.6E-47 T 05-07-2017 IPR019613 Protein of unknown function DUF4198 K08M4_RS03965 3a99cd18ec865700e053d58b5b95c3a0 86 Pfam PF00550 Phosphopantetheine attachment site 7 80 2.2E-9 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS03965 3a99cd18ec865700e053d58b5b95c3a0 86 Gene3D G3DSA:1.10.1200.10 3 84 2.3E-17 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS03965 3a99cd18ec865700e053d58b5b95c3a0 86 SUPERFAMILY SSF47336 5 85 2.22E-13 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 SUPERFAMILY SSF82693 41 133 5.49E-22 T 05-07-2017 K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 6.9E-27 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 6.9E-27 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 6.9E-27 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 6.9E-27 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 6.9E-27 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 6.9E-27 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 Gene3D G3DSA:1.10.3850.10 795 1022 3.8E-57 T 05-07-2017 K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 Gene3D G3DSA:3.30.2090.10 707 786 1.5E-4 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 Gene3D G3DSA:1.20.1640.10 284 499 4.1E-48 T 05-07-2017 K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 SUPERFAMILY SSF82693 145 181 1.31E-10 T 05-07-2017 K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 SUPERFAMILY SSF82693 267 325 1.31E-10 T 05-07-2017 K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 SUPERFAMILY SSF82866 791 1027 2.49E-48 T 05-07-2017 K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 Gene3D G3DSA:3.30.70.1430 41 136 5.8E-23 T 05-07-2017 K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 Gene3D G3DSA:3.30.2090.10 185 263 1.7E-9 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 SUPERFAMILY SSF82714 707 787 3.4E-5 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 SUPERFAMILY SSF82714 184 263 9.02E-11 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 SUPERFAMILY SSF82866 290 490 2.75E-38 T 05-07-2017 K08M4_RS03035 c13d8343e0e0f548c0250583437f2225 1029 Pfam PF00873 AcrB/AcrD/AcrF family 7 1021 4.0E-162 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS09350 7bebc94a0b23bbe25e873d511aff88b7 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 314 1.8E-42 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS09350 7bebc94a0b23bbe25e873d511aff88b7 320 Gene3D G3DSA:1.10.3720.10 177 306 2.2E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS09350 7bebc94a0b23bbe25e873d511aff88b7 320 Gene3D G3DSA:1.10.3720.10 72 137 2.2E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS09350 7bebc94a0b23bbe25e873d511aff88b7 320 SUPERFAMILY SSF161098 69 137 1.8E-20 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS09350 7bebc94a0b23bbe25e873d511aff88b7 320 SUPERFAMILY SSF161098 177 298 1.8E-20 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS20085 4ea1fdb7b0a62a253a5beab234f0b6b6 603 Pfam PF14280 Domain of unknown function (DUF4365) 21 138 6.2E-13 T 05-07-2017 IPR025375 Domain of unknown function DUF4365 K08M4_RS16535 1c3e13357890505add87e0b128d0c5d3 525 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 05-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site K08M4_RS16535 1c3e13357890505add87e0b128d0c5d3 525 Hamap MF_00968 ATP-dependent RNA helicase RhlE [rhlE]. 1 523 49.898 T 05-07-2017 IPR028622 ATP-dependent RNA helicase RhlE GO:0004004|GO:0042255 K08M4_RS16535 1c3e13357890505add87e0b128d0c5d3 525 Pfam PF00270 DEAD/DEAH box helicase 26 192 1.5E-45 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS16535 1c3e13357890505add87e0b128d0c5d3 525 SUPERFAMILY SSF52540 73 356 1.44E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16535 1c3e13357890505add87e0b128d0c5d3 525 Gene3D G3DSA:3.40.50.300 1 216 5.7E-78 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16535 1c3e13357890505add87e0b128d0c5d3 525 SMART SM00487 20 221 4.7E-60 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS16535 1c3e13357890505add87e0b128d0c5d3 525 SMART SM00490 257 338 3.0E-32 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS16535 1c3e13357890505add87e0b128d0c5d3 525 Pfam PF00271 Helicase conserved C-terminal domain 231 338 6.2E-28 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS16535 1c3e13357890505add87e0b128d0c5d3 525 Gene3D G3DSA:3.40.50.300 217 372 6.6E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16390 be37412133fcc7641b3e3bbb64ed04f4 461 Gene3D G3DSA:2.60.40.1180 392 458 2.1E-6 T 05-07-2017 IPR013780 Glycosyl hydrolase, all-beta K08M4_RS16390 be37412133fcc7641b3e3bbb64ed04f4 461 SUPERFAMILY SSF51011 394 458 5.6E-6 T 05-07-2017 K08M4_RS16390 be37412133fcc7641b3e3bbb64ed04f4 461 SMART SM00642 13 383 1.2E-26 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS16390 be37412133fcc7641b3e3bbb64ed04f4 461 Gene3D G3DSA:3.20.20.80 11 384 7.0E-72 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS16390 be37412133fcc7641b3e3bbb64ed04f4 461 Pfam PF00128 Alpha amylase, catalytic domain 33 246 1.9E-18 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS16390 be37412133fcc7641b3e3bbb64ed04f4 461 PRINTS PR00110 Alpha-amylase signature 210 221 5.0E-16 T 05-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 K08M4_RS16390 be37412133fcc7641b3e3bbb64ed04f4 461 PRINTS PR00110 Alpha-amylase signature 239 257 5.0E-16 T 05-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 K08M4_RS16390 be37412133fcc7641b3e3bbb64ed04f4 461 PRINTS PR00110 Alpha-amylase signature 305 317 5.0E-16 T 05-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 K08M4_RS16390 be37412133fcc7641b3e3bbb64ed04f4 461 PRINTS PR00110 Alpha-amylase signature 64 81 5.0E-16 T 05-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 K08M4_RS16390 be37412133fcc7641b3e3bbb64ed04f4 461 PRINTS PR00110 Alpha-amylase signature 97 108 5.0E-16 T 05-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 K08M4_RS16390 be37412133fcc7641b3e3bbb64ed04f4 461 SUPERFAMILY SSF51445 12 385 2.45E-60 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS04925 011b6598ba1d399b5215f6492d1067d4 170 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 72 85 - T 05-07-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 K08M4_RS04925 011b6598ba1d399b5215f6492d1067d4 170 Pfam PF00994 Probable molybdopterin binding domain 14 155 8.7E-34 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS04925 011b6598ba1d399b5215f6492d1067d4 170 SUPERFAMILY SSF53218 7 168 1.83E-46 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS04925 011b6598ba1d399b5215f6492d1067d4 170 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 7 168 7.7E-84 T 05-07-2017 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 K08M4_RS04925 011b6598ba1d399b5215f6492d1067d4 170 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 12 152 5.1E-37 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS04925 011b6598ba1d399b5215f6492d1067d4 170 Gene3D G3DSA:3.40.980.10 7 167 3.7E-50 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS04925 011b6598ba1d399b5215f6492d1067d4 170 SMART SM00852 14 158 2.2E-27 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS04925 011b6598ba1d399b5215f6492d1067d4 170 PIRSF PIRSF006443 1 166 4.3E-66 T 05-07-2017 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 K08M4_RS14610 5210bcdc997cbf0f9e69ca314dca6893 575 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 534 566 0.0012 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS14610 5210bcdc997cbf0f9e69ca314dca6893 575 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 270 1.5E-7 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS14610 5210bcdc997cbf0f9e69ca314dca6893 575 SUPERFAMILY SSF52540 303 553 4.37E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14610 5210bcdc997cbf0f9e69ca314dca6893 575 ProSitePatterns PS00211 ABC transporters family signature. 455 469 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS14610 5210bcdc997cbf0f9e69ca314dca6893 575 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS14610 5210bcdc997cbf0f9e69ca314dca6893 575 Pfam PF00005 ABC transporter 330 483 3.7E-34 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS14610 5210bcdc997cbf0f9e69ca314dca6893 575 Pfam PF00005 ABC transporter 24 181 4.6E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS14610 5210bcdc997cbf0f9e69ca314dca6893 575 Gene3D G3DSA:3.40.50.300 301 555 1.5E-81 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14610 5210bcdc997cbf0f9e69ca314dca6893 575 Gene3D G3DSA:3.40.50.300 2 255 4.3E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14610 5210bcdc997cbf0f9e69ca314dca6893 575 SMART SM00382 338 534 1.7E-16 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS14610 5210bcdc997cbf0f9e69ca314dca6893 575 SMART SM00382 32 231 9.4E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS14610 5210bcdc997cbf0f9e69ca314dca6893 575 SUPERFAMILY SSF52540 3 252 3.77E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00900 b6d2a7f6c9cd5f26d63dee7d59325a57 319 Gene3D G3DSA:3.30.70.270 141 302 3.9E-52 T 05-07-2017 K08M4_RS00900 b6d2a7f6c9cd5f26d63dee7d59325a57 319 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 138 297 6.9E-47 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS00900 b6d2a7f6c9cd5f26d63dee7d59325a57 319 SUPERFAMILY SSF55073 144 300 1.26E-47 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS00900 b6d2a7f6c9cd5f26d63dee7d59325a57 319 Pfam PF00990 Diguanylate cyclase, GGDEF domain 139 294 7.6E-44 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS00900 b6d2a7f6c9cd5f26d63dee7d59325a57 319 SMART SM00267 128 298 1.1E-51 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS21590 274c80417e624ae20d71f427ffd54030 426 Gene3D G3DSA:3.40.50.150 135 411 8.7E-96 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS21590 274c80417e624ae20d71f427ffd54030 426 Pfam PF02353 Mycolic acid cyclopropane synthetase 140 407 3.4E-82 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS21590 274c80417e624ae20d71f427ffd54030 426 PIRSF PIRSF003085 6 424 2.4E-123 T 05-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 K08M4_RS21590 274c80417e624ae20d71f427ffd54030 426 SUPERFAMILY SSF53335 26 364 9.29E-91 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS08055 ac9a7b393ad9c6b78281258bede65522 506 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 18 444 1.3E-140 T 05-07-2017 IPR002823 Protein of unknown function DUF112, transmembrane K08M4_RS16595 656f1f0d64046fe68ecfb7b4ab711a65 485 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 81 5.9E-15 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS16595 656f1f0d64046fe68ecfb7b4ab711a65 485 SUPERFAMILY SSF46785 18 84 2.72E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16595 656f1f0d64046fe68ecfb7b4ab711a65 485 Gene3D G3DSA:3.40.640.10 158 373 1.7E-49 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS16595 656f1f0d64046fe68ecfb7b4ab711a65 485 SMART SM00345 22 81 3.8E-18 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS16595 656f1f0d64046fe68ecfb7b4ab711a65 485 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 2.9E-6 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS16595 656f1f0d64046fe68ecfb7b4ab711a65 485 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 2.9E-6 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS16595 656f1f0d64046fe68ecfb7b4ab711a65 485 Gene3D G3DSA:1.10.10.10 18 82 1.9E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16595 656f1f0d64046fe68ecfb7b4ab711a65 485 SUPERFAMILY SSF53383 122 482 7.78E-74 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS16595 656f1f0d64046fe68ecfb7b4ab711a65 485 Pfam PF00155 Aminotransferase class I and II 135 420 4.0E-24 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS10305 f04ca3ddb9db80ab3a992dd616ba5921 476 Gene3D G3DSA:2.30.38.10 327 374 5.9E-5 T 05-07-2017 K08M4_RS10305 f04ca3ddb9db80ab3a992dd616ba5921 476 Gene3D G3DSA:3.40.50.980 169 313 3.4E-23 T 05-07-2017 K08M4_RS10305 f04ca3ddb9db80ab3a992dd616ba5921 476 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 05-07-2017 IPR020845 AMP-binding, conserved site K08M4_RS10305 f04ca3ddb9db80ab3a992dd616ba5921 476 Pfam PF00501 AMP-binding enzyme 14 380 1.1E-46 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 K08M4_RS10305 f04ca3ddb9db80ab3a992dd616ba5921 476 Gene3D G3DSA:3.30.300.30 375 467 2.7E-13 T 05-07-2017 K08M4_RS10305 f04ca3ddb9db80ab3a992dd616ba5921 476 SUPERFAMILY SSF56801 5 454 1.31E-77 T 05-07-2017 K08M4_RS10305 f04ca3ddb9db80ab3a992dd616ba5921 476 Gene3D G3DSA:3.40.50.980 7 168 7.0E-22 T 05-07-2017 K08M4_RS10305 f04ca3ddb9db80ab3a992dd616ba5921 476 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 33 465 1.3E-118 T 05-07-2017 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 K08M4_RS17100 9f3cc47d611b562d2ed0ca6947c1d2c4 243 SMART SM00052 1 238 2.0E-39 T 05-07-2017 IPR001633 EAL domain K08M4_RS17100 9f3cc47d611b562d2ed0ca6947c1d2c4 243 Gene3D G3DSA:3.20.20.450 7 239 2.7E-55 T 05-07-2017 IPR001633 EAL domain K08M4_RS17100 9f3cc47d611b562d2ed0ca6947c1d2c4 243 SUPERFAMILY SSF141868 7 240 1.96E-58 T 05-07-2017 IPR001633 EAL domain K08M4_RS17100 9f3cc47d611b562d2ed0ca6947c1d2c4 243 Pfam PF00563 EAL domain 7 233 9.9E-52 T 05-07-2017 IPR001633 EAL domain K08M4_RS12945 795ef355024555ee74e15afde37bfa25 181 Pfam PF06041 Bacterial protein of unknown function (DUF924) 8 178 3.6E-61 T 05-07-2017 IPR010323 Protein of unknown function DUF924 K08M4_RS12945 795ef355024555ee74e15afde37bfa25 181 SUPERFAMILY SSF48452 2 177 1.18E-66 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS12945 795ef355024555ee74e15afde37bfa25 181 Gene3D G3DSA:1.25.40.10 82 181 1.6E-38 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS12945 795ef355024555ee74e15afde37bfa25 181 Gene3D G3DSA:1.20.58.320 3 80 4.4E-26 T 05-07-2017 K08M4_RS02400 83753a2d8f568de7e25fee0df12a67fc 153 SUPERFAMILY SSF55826 3 151 2.62E-34 T 05-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 K08M4_RS02400 83753a2d8f568de7e25fee0df12a67fc 153 Gene3D G3DSA:3.90.960.10 3 152 1.1E-36 T 05-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 K08M4_RS02400 83753a2d8f568de7e25fee0df12a67fc 153 Pfam PF04073 Aminoacyl-tRNA editing domain 23 142 1.7E-28 T 05-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 K08M4_RS18940 8928a77caf47c91004ec0396e16297ec 203 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 8 188 6.4E-57 T 05-07-2017 IPR010976 Beta-phosphoglucomutase hydrolase K08M4_RS18940 8928a77caf47c91004ec0396e16297ec 203 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 101 188 2.6E-12 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS18940 8928a77caf47c91004ec0396e16297ec 203 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 188 7.8E-27 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS18940 8928a77caf47c91004ec0396e16297ec 203 Gene3D G3DSA:3.40.50.1000 2 21 5.4E-33 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS18940 8928a77caf47c91004ec0396e16297ec 203 Gene3D G3DSA:3.40.50.1000 93 193 5.4E-33 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS18940 8928a77caf47c91004ec0396e16297ec 203 SUPERFAMILY SSF56784 8 194 8.79E-43 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS18940 8928a77caf47c91004ec0396e16297ec 203 Gene3D G3DSA:1.10.150.240 22 71 4.2E-6 T 05-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 K08M4_RS16700 5d22dcf6842ffbc55b9ac27172bb555f 351 PRINTS PR00183 E.coli/Salmonella-type porin signature 93 115 2.3E-7 T 05-07-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 K08M4_RS16700 5d22dcf6842ffbc55b9ac27172bb555f 351 PRINTS PR00183 E.coli/Salmonella-type porin signature 22 38 2.3E-7 T 05-07-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 K08M4_RS16700 5d22dcf6842ffbc55b9ac27172bb555f 351 PRINTS PR00183 E.coli/Salmonella-type porin signature 301 320 2.3E-7 T 05-07-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 K08M4_RS16700 5d22dcf6842ffbc55b9ac27172bb555f 351 PRINTS PR00183 E.coli/Salmonella-type porin signature 149 171 2.3E-7 T 05-07-2017 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 K08M4_RS16700 5d22dcf6842ffbc55b9ac27172bb555f 351 Pfam PF00267 Gram-negative porin 42 346 2.1E-16 T 05-07-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 K08M4_RS16700 5d22dcf6842ffbc55b9ac27172bb555f 351 Gene3D G3DSA:2.40.160.10 22 349 4.1E-51 T 05-07-2017 IPR023614 Porin domain K08M4_RS16700 5d22dcf6842ffbc55b9ac27172bb555f 351 SUPERFAMILY SSF56935 22 349 1.31E-52 T 05-07-2017 K08M4_RS20170 bf8047253282594470994640828e540a 310 Pfam PF03466 LysR substrate binding domain 90 291 9.4E-38 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS20170 bf8047253282594470994640828e540a 310 Gene3D G3DSA:3.40.190.10 175 259 3.5E-18 T 05-07-2017 K08M4_RS20170 bf8047253282594470994640828e540a 310 SUPERFAMILY SSF53850 90 295 2.35E-37 T 05-07-2017 K08M4_RS20170 bf8047253282594470994640828e540a 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.1E-14 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS20170 bf8047253282594470994640828e540a 310 SUPERFAMILY SSF46785 3 111 2.09E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20170 bf8047253282594470994640828e540a 310 Gene3D G3DSA:1.10.10.10 2 84 1.0E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20170 bf8047253282594470994640828e540a 310 Gene3D G3DSA:3.40.190.10 91 174 7.7E-20 T 05-07-2017 K08M4_RS09490 5db376d47b29c96b300954e0c45c2e4a 346 Gene3D G3DSA:3.40.640.10 43 251 1.7E-71 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS09490 5db376d47b29c96b300954e0c45c2e4a 346 SUPERFAMILY SSF53383 11 345 5.98E-76 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS09490 5db376d47b29c96b300954e0c45c2e4a 346 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 6 343 2.4E-117 T 05-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 K08M4_RS09490 5db376d47b29c96b300954e0c45c2e4a 346 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 345 53.356 T 05-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 K08M4_RS09490 5db376d47b29c96b300954e0c45c2e4a 346 Gene3D G3DSA:3.90.1150.10 252 345 1.9E-10 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS09490 5db376d47b29c96b300954e0c45c2e4a 346 Pfam PF00155 Aminotransferase class I and II 45 338 3.3E-55 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS09490 5db376d47b29c96b300954e0c45c2e4a 346 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 206 215 - T 05-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 K08M4_RS09395 779d19e5ee4e44ea137f6b044150230b 393 PIRSF PIRSF000014 1 393 5.0E-160 T 05-07-2017 IPR009154 Membrane-bound tetrahaem cytochrome TorC/YecK GO:0005506|GO:0009055|GO:0009276|GO:0016021|GO:0020037 K08M4_RS09395 779d19e5ee4e44ea137f6b044150230b 393 Gene3D G3DSA:1.10.3820.10 12 189 5.1E-30 T 05-07-2017 K08M4_RS09395 779d19e5ee4e44ea137f6b044150230b 393 Gene3D G3DSA:1.10.3820.10 338 344 5.1E-30 T 05-07-2017 K08M4_RS09395 779d19e5ee4e44ea137f6b044150230b 393 SUPERFAMILY SSF48695 12 186 1.13E-60 T 05-07-2017 IPR011031 Multihaem cytochrome K08M4_RS09395 779d19e5ee4e44ea137f6b044150230b 393 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 16 186 2.6E-72 T 05-07-2017 IPR005126 NapC/NirT cytochrome c, N-terminal K08M4_RS09395 779d19e5ee4e44ea137f6b044150230b 393 TIGRFAM TIGR02162 torC: trimethylamine-N-oxide reductase c-type cytochrome TorC 7 393 2.8E-182 T 05-07-2017 IPR009154 Membrane-bound tetrahaem cytochrome TorC/YecK GO:0005506|GO:0009055|GO:0009276|GO:0016021|GO:0020037 K08M4_RS02950 647b59e39cd3015b6e0bd7d4b2062e14 342 Pfam PF00005 ABC transporter 20 164 2.4E-35 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS02950 647b59e39cd3015b6e0bd7d4b2062e14 342 SUPERFAMILY SSF52540 5 243 8.73E-80 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02950 647b59e39cd3015b6e0bd7d4b2062e14 342 Gene3D G3DSA:3.40.50.300 4 236 1.4E-75 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02950 647b59e39cd3015b6e0bd7d4b2062e14 342 SMART SM00382 29 216 1.7E-18 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS02950 647b59e39cd3015b6e0bd7d4b2062e14 342 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS02950 647b59e39cd3015b6e0bd7d4b2062e14 342 SUPERFAMILY SSF50331 250 342 8.93E-7 T 05-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal K08M4_RS15695 b1c334fa6e4548f74cb4e8054c18082a 389 PIRSF PIRSF006078 1 385 1.2E-124 T 05-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 K08M4_RS15695 b1c334fa6e4548f74cb4e8054c18082a 389 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 383 2.4E-136 T 05-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 K08M4_RS15695 b1c334fa6e4548f74cb4e8054c18082a 389 SUPERFAMILY SSF110738 1 383 3.01E-122 T 05-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 K08M4_RS15695 b1c334fa6e4548f74cb4e8054c18082a 389 Gene3D G3DSA:3.40.50.10350 270 383 1.5E-26 T 05-07-2017 IPR018197 Glycerate kinase, restriction-enzyme-like fold K08M4_RS15695 b1c334fa6e4548f74cb4e8054c18082a 389 Gene3D G3DSA:3.90.1510.10 42 269 3.7E-84 T 05-07-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 K08M4_RS15695 b1c334fa6e4548f74cb4e8054c18082a 389 Pfam PF02595 Glycerate kinase family 3 381 4.6E-133 T 05-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 K08M4_RS21760 caba3f5757b7847a8da6f5cb7fa28d23 427 Pfam PF00144 Beta-lactamase 110 419 9.4E-26 T 05-07-2017 IPR001466 Beta-lactamase-related K08M4_RS21760 caba3f5757b7847a8da6f5cb7fa28d23 427 Gene3D G3DSA:3.40.710.10 114 422 7.3E-34 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS21760 caba3f5757b7847a8da6f5cb7fa28d23 427 SUPERFAMILY SSF56601 52 411 1.57E-51 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS06285 09cc1e4b39c0b54a8f4b2e7986347cc8 419 Pfam PF11301 Protein of unknown function (DUF3103) 59 418 1.3E-165 T 05-07-2017 IPR021452 Protein of unknown function DUF3103 K08M4_RS19665 fd5888068bcd36e7a64148caa6011b6a 296 SUPERFAMILY SSF46785 6 83 3.31E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19665 fd5888068bcd36e7a64148caa6011b6a 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.6E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19665 fd5888068bcd36e7a64148caa6011b6a 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.6E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19665 fd5888068bcd36e7a64148caa6011b6a 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.6E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19665 fd5888068bcd36e7a64148caa6011b6a 296 Pfam PF03466 LysR substrate binding domain 89 294 5.2E-29 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS19665 fd5888068bcd36e7a64148caa6011b6a 296 Gene3D G3DSA:1.10.10.10 2 81 1.2E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19665 fd5888068bcd36e7a64148caa6011b6a 296 Gene3D G3DSA:3.40.190.10 90 192 1.8E-11 T 05-07-2017 K08M4_RS19665 fd5888068bcd36e7a64148caa6011b6a 296 SUPERFAMILY SSF53850 88 293 2.65E-30 T 05-07-2017 K08M4_RS19665 fd5888068bcd36e7a64148caa6011b6a 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 6.2E-17 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 Pfam PF00344 SecY translocase 76 418 2.2E-117 T 05-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 20 430 2.0E-134 T 05-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 PIRSF PIRSF004557 10 442 1.8E-121 T 05-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 ProSitePatterns PS00755 Protein secY signature 1. 76 95 - T 05-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 Gene3D G3DSA:1.10.3370.10 15 438 1.2E-162 T 05-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 ProSitePatterns PS00756 Protein secY signature 2. 171 188 - T 05-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 371 389 1.9E-95 T 05-07-2017 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 403 421 1.9E-95 T 05-07-2017 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 152 177 1.9E-95 T 05-07-2017 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 178 201 1.9E-95 T 05-07-2017 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 116 139 1.9E-95 T 05-07-2017 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 23 41 1.9E-95 T 05-07-2017 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 316 338 1.9E-95 T 05-07-2017 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 75 95 1.9E-95 T 05-07-2017 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 270 289 1.9E-95 T 05-07-2017 K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 Hamap MF_01465 Protein translocase subunit SecY [secY]. 9 434 29.126 T 05-07-2017 IPR026593 Protein translocase subunit SecY K08M4_RS01565 bf3be2a301bbda51c9593780b1e0f103 444 SUPERFAMILY SSF103491 15 425 3.53E-130 T 05-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 K08M4_RS04460 2038a30c19fd86e7ec1bcf98c3680f7b 399 Pfam PF07670 Nucleoside recognition 87 182 4.5E-7 T 05-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 K08M4_RS04460 2038a30c19fd86e7ec1bcf98c3680f7b 399 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 5 78 1.1E-23 T 05-07-2017 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 K08M4_RS04460 2038a30c19fd86e7ec1bcf98c3680f7b 399 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 1 395 7.7E-136 T 05-07-2017 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 K08M4_RS04460 2038a30c19fd86e7ec1bcf98c3680f7b 399 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 189 395 1.7E-70 T 05-07-2017 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 K08M4_RS02870 3265af546e46fce3d494c95dded01f8e 296 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 281 1.1E-104 T 05-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 K08M4_RS02870 3265af546e46fce3d494c95dded01f8e 296 Pfam PF02569 Pantoate-beta-alanine ligase 3 278 1.6E-100 T 05-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 K08M4_RS02870 3265af546e46fce3d494c95dded01f8e 296 SUPERFAMILY SSF52374 1 281 6.97E-106 T 05-07-2017 K08M4_RS02870 3265af546e46fce3d494c95dded01f8e 296 Hamap MF_00158 Pantothenate synthetase [panC]. 2 280 39.301 T 05-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 K08M4_RS02870 3265af546e46fce3d494c95dded01f8e 296 Gene3D G3DSA:3.40.50.620 1 175 5.9E-78 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS02870 3265af546e46fce3d494c95dded01f8e 296 Gene3D G3DSA:3.30.1300.10 177 289 1.3E-28 T 05-07-2017 K08M4_RS02870 3265af546e46fce3d494c95dded01f8e 296 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 24 63 4.1E-10 T 05-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 K08M4_RS09425 47a74bd9bcb199683450a68a0dadb986 284 Gene3D G3DSA:3.40.50.720 106 242 5.9E-12 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS09425 47a74bd9bcb199683450a68a0dadb986 284 Gene3D G3DSA:3.40.50.720 3 105 5.1E-7 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS09425 47a74bd9bcb199683450a68a0dadb986 284 Pfam PF13460 NAD(P)H-binding 9 189 7.5E-10 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS09425 47a74bd9bcb199683450a68a0dadb986 284 SUPERFAMILY SSF51735 4 275 1.16E-21 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS05330 cd2376eca681b63468f43caa8edeeb44 259 Pfam PF01925 Sulfite exporter TauE/SafE 12 250 3.8E-44 T 05-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 K08M4_RS10565 72e178ece4a21e877a12f1f31218ce42 402 Pfam PF00364 Biotin-requiring enzyme 4 76 3.6E-18 T 05-07-2017 IPR000089 Biotin/lipoyl attachment K08M4_RS10565 72e178ece4a21e877a12f1f31218ce42 402 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 402 4.3E-188 T 05-07-2017 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 K08M4_RS10565 72e178ece4a21e877a12f1f31218ce42 402 SUPERFAMILY SSF51230 1 95 6.54E-24 T 05-07-2017 IPR011053 Single hybrid motif K08M4_RS10565 72e178ece4a21e877a12f1f31218ce42 402 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 172 400 2.7E-82 T 05-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 K08M4_RS10565 72e178ece4a21e877a12f1f31218ce42 402 Pfam PF02817 e3 binding domain 113 145 7.0E-13 T 05-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 K08M4_RS10565 72e178ece4a21e877a12f1f31218ce42 402 Gene3D G3DSA:3.30.559.10 162 400 1.1E-91 T 05-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 K08M4_RS10565 72e178ece4a21e877a12f1f31218ce42 402 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 05-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 K08M4_RS10565 72e178ece4a21e877a12f1f31218ce42 402 SUPERFAMILY SSF52777 173 401 6.23E-90 T 05-07-2017 K08M4_RS10565 72e178ece4a21e877a12f1f31218ce42 402 Gene3D G3DSA:2.40.50.100 1 96 1.9E-25 T 05-07-2017 K08M4_RS10565 72e178ece4a21e877a12f1f31218ce42 402 SUPERFAMILY SSF47005 107 149 6.02E-11 T 05-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 K08M4_RS10565 72e178ece4a21e877a12f1f31218ce42 402 Gene3D G3DSA:4.10.320.10 113 152 6.3E-19 T 05-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 K08M4_RS15000 9835218c466e432dbb5e87a29ca5db9e 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 43 1.9E-24 T 05-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS15000 9835218c466e432dbb5e87a29ca5db9e 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 39 2.0E-13 T 05-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS15000 9835218c466e432dbb5e87a29ca5db9e 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.832 T 05-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS15000 9835218c466e432dbb5e87a29ca5db9e 44 Pfam PF00468 Ribosomal protein L34 1 43 5.4E-23 T 05-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS15000 9835218c466e432dbb5e87a29ca5db9e 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 05-07-2017 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS06370 3848b9b037d284be5427da0f2b302b47 456 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 90 105 - T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS06370 3848b9b037d284be5427da0f2b302b47 456 Pfam PF01235 Sodium:alanine symporter family 50 446 1.7E-138 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS06370 3848b9b037d284be5427da0f2b302b47 456 PRINTS PR00175 Sodium/alanine symporter signature 182 200 1.4E-52 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS06370 3848b9b037d284be5427da0f2b302b47 456 PRINTS PR00175 Sodium/alanine symporter signature 90 112 1.4E-52 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS06370 3848b9b037d284be5427da0f2b302b47 456 PRINTS PR00175 Sodium/alanine symporter signature 210 229 1.4E-52 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS06370 3848b9b037d284be5427da0f2b302b47 456 PRINTS PR00175 Sodium/alanine symporter signature 305 323 1.4E-52 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS06370 3848b9b037d284be5427da0f2b302b47 456 PRINTS PR00175 Sodium/alanine symporter signature 410 430 1.4E-52 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS06370 3848b9b037d284be5427da0f2b302b47 456 PRINTS PR00175 Sodium/alanine symporter signature 351 373 1.4E-52 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS06370 3848b9b037d284be5427da0f2b302b47 456 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 439 2.1E-157 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 Gene3D G3DSA:2.40.30.10 301 392 2.4E-47 T 05-07-2017 K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 7.3E-17 T 05-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.7E-23 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.7E-23 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.7E-23 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.7E-23 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.7E-23 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 58.946 T 05-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 SUPERFAMILY SSF50465 302 394 1.99E-35 T 05-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 05-07-2017 IPR031157 Tr-type G domain, conserved site K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 Gene3D G3DSA:3.40.50.300 3 209 1.1E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 8.6E-58 T 05-07-2017 K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 Gene3D G3DSA:2.40.30.10 210 297 3.3E-33 T 05-07-2017 K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 5.9E-14 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 SUPERFAMILY SSF52540 6 219 1.84E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 1.9E-33 T 05-07-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 SUPERFAMILY SSF50447 205 301 4.52E-29 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain K08M4_RS00795 ada78cc4cd831fca22d04e5e064aa5f2 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 393 5.2E-228 T 05-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 K08M4_RS12575 f76808c2e0aedad5d200a7fc402d6d7a 398 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 25 381 1.8E-128 T 05-07-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 K08M4_RS12575 f76808c2e0aedad5d200a7fc402d6d7a 398 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 23 390 41.226 T 05-07-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 K08M4_RS12575 f76808c2e0aedad5d200a7fc402d6d7a 398 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 340 364 - T 05-07-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 K08M4_RS12575 f76808c2e0aedad5d200a7fc402d6d7a 398 Pfam PF01098 Cell cycle protein 27 381 7.8E-113 T 05-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 K08M4_RS05855 7ef9ad0b65af5410b8f9f8452d7a5ae8 374 Pfam PF00246 Zinc carboxypeptidase 124 341 1.0E-21 T 05-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 K08M4_RS05855 7ef9ad0b65af5410b8f9f8452d7a5ae8 374 Gene3D G3DSA:3.40.630.10 100 343 8.3E-44 T 05-07-2017 K08M4_RS05855 7ef9ad0b65af5410b8f9f8452d7a5ae8 374 SMART SM00631 112 347 8.5E-4 T 05-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 K08M4_RS05855 7ef9ad0b65af5410b8f9f8452d7a5ae8 374 SUPERFAMILY SSF53187 105 372 6.62E-60 T 05-07-2017 K08M4_RS03375 298df9424abd3edf8337c735113700fc 166 Pfam PF07811 TadE-like protein 9 51 1.2E-8 T 05-07-2017 IPR012495 TadE-like K08M4_RS11285 42826d5031ae669aa73bf2483d7f96b6 147 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 18 145 1.4E-48 T 05-07-2017 IPR003791 Protein of unknown function UPF0178 K08M4_RS11285 42826d5031ae669aa73bf2483d7f96b6 147 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 30.628 T 05-07-2017 IPR003791 Protein of unknown function UPF0178 K08M4_RS04215 992c7cac72209d89cf8fec580b2f1647 260 Pfam PF01311 Bacterial export proteins, family 1 13 243 5.1E-57 T 05-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 K08M4_RS04215 992c7cac72209d89cf8fec580b2f1647 260 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 181 203 1.7E-16 T 05-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 K08M4_RS04215 992c7cac72209d89cf8fec580b2f1647 260 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 21 42 1.7E-16 T 05-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 K08M4_RS04215 992c7cac72209d89cf8fec580b2f1647 260 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 203 222 1.7E-16 T 05-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 K08M4_RS04215 992c7cac72209d89cf8fec580b2f1647 260 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 1.7E-16 T 05-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 K08M4_RS04215 992c7cac72209d89cf8fec580b2f1647 260 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 13 255 5.1E-75 T 05-07-2017 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 K08M4_RS11380 4c736031354e1b05bf4eb8a8aa76dfa4 344 Pfam PF09383 NIL domain 268 339 9.7E-21 T 05-07-2017 IPR018449 NIL domain K08M4_RS11380 4c736031354e1b05bf4eb8a8aa76dfa4 344 Gene3D G3DSA:3.30.70.260 237 343 6.9E-31 T 05-07-2017 K08M4_RS11380 4c736031354e1b05bf4eb8a8aa76dfa4 344 TIGRFAM TIGR02314 ABC_MetN: D-methionine ABC transporter, ATP-binding protein 1 343 1.0E-197 T 05-07-2017 IPR012692 ABC transporter, methionine import, ATP-binding protein MetN, proteobacteria GO:0005524|GO:0009276|GO:0048473|GO:0048474 K08M4_RS11380 4c736031354e1b05bf4eb8a8aa76dfa4 344 SMART SM00382 30 235 5.0E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS11380 4c736031354e1b05bf4eb8a8aa76dfa4 344 SUPERFAMILY SSF55021 248 343 3.43E-25 T 05-07-2017 K08M4_RS11380 4c736031354e1b05bf4eb8a8aa76dfa4 344 Pfam PF00005 ABC transporter 23 169 8.6E-35 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS11380 4c736031354e1b05bf4eb8a8aa76dfa4 344 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS11380 4c736031354e1b05bf4eb8a8aa76dfa4 344 SUPERFAMILY SSF52540 1 239 3.59E-82 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11380 4c736031354e1b05bf4eb8a8aa76dfa4 344 Gene3D G3DSA:3.40.50.300 1 236 3.9E-82 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11380 4c736031354e1b05bf4eb8a8aa76dfa4 344 SMART SM00930 265 340 2.2E-27 T 05-07-2017 IPR018449 NIL domain K08M4_RS21675 ffb15a07418bb9024a2d3087feb13e49 273 Pfam PF01844 HNH endonuclease 201 249 1.7E-10 T 05-07-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 K08M4_RS21675 ffb15a07418bb9024a2d3087feb13e49 273 SMART SM00507 188 246 2.2E-10 T 05-07-2017 IPR003615 HNH nuclease K08M4_RS03195 7e0aa2b5c68be6a4d9e5bde1ce130904 151 Pfam PF00583 Acetyltransferase (GNAT) family 47 121 1.0E-16 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS03195 7e0aa2b5c68be6a4d9e5bde1ce130904 151 SUPERFAMILY SSF55729 1 145 2.53E-32 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS03195 7e0aa2b5c68be6a4d9e5bde1ce130904 151 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 12 143 2.2E-39 T 05-07-2017 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 K08M4_RS03195 7e0aa2b5c68be6a4d9e5bde1ce130904 151 Gene3D G3DSA:3.40.630.30 7 146 1.5E-32 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS20005 28dc1f6b97216ea6806fe8b45a1e713d 289 Pfam PF05929 Phage capsid scaffolding protein (GPO) serine peptidase 6 283 1.3E-45 T 05-07-2017 IPR009228 Capsid scaffolding protein GpO GO:0019069 K08M4_RS15345 779baa6ef77a5b780f4ff28be6dd3180 477 Pfam PF02378 Phosphotransferase system, EIIC 126 415 2.3E-27 T 05-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 K08M4_RS15345 779baa6ef77a5b780f4ff28be6dd3180 477 Gene3D G3DSA:3.30.1360.60 22 98 2.3E-24 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS15345 779baa6ef77a5b780f4ff28be6dd3180 477 Pfam PF00367 phosphotransferase system, EIIB 30 61 8.1E-14 T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS15345 779baa6ef77a5b780f4ff28be6dd3180 477 SUPERFAMILY SSF55604 27 98 4.05E-20 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS15345 779baa6ef77a5b780f4ff28be6dd3180 477 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 39 56 - T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS03495 dd0d3ea2cde0e439ed993cabae7b2f34 359 Gene3D G3DSA:3.40.140.10 1 124 7.4E-33 T 05-07-2017 K08M4_RS03495 dd0d3ea2cde0e439ed993cabae7b2f34 359 Pfam PF01872 RibD C-terminal domain 143 348 8.5E-50 T 05-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 K08M4_RS03495 dd0d3ea2cde0e439ed993cabae7b2f34 359 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 95 4.7E-18 T 05-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 K08M4_RS03495 dd0d3ea2cde0e439ed993cabae7b2f34 359 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 2 349 2.8E-128 T 05-07-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 K08M4_RS03495 dd0d3ea2cde0e439ed993cabae7b2f34 359 Gene3D G3DSA:3.40.430.10 125 353 2.2E-65 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 K08M4_RS03495 dd0d3ea2cde0e439ed993cabae7b2f34 359 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 142 353 1.1E-57 T 05-07-2017 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 K08M4_RS03495 dd0d3ea2cde0e439ed993cabae7b2f34 359 SUPERFAMILY SSF53597 140 351 9.56E-54 T 05-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 K08M4_RS03495 dd0d3ea2cde0e439ed993cabae7b2f34 359 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 46 84 - T 05-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 K08M4_RS03495 dd0d3ea2cde0e439ed993cabae7b2f34 359 PIRSF PIRSF006769 1 355 4.8E-123 T 05-07-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 K08M4_RS03495 dd0d3ea2cde0e439ed993cabae7b2f34 359 SUPERFAMILY SSF53927 1 141 9.7E-45 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 K08M4_RS20270 974813006ce57532b558bb82d2071e0f 155 Pfam PF10517 Electron transfer DM13 59 154 1.3E-20 T 05-07-2017 IPR019545 DM13 domain K08M4_RS13490 ff036588869965b55fede54e3710d474 211 Pfam PF08238 Sel1 repeat 108 143 2.6E-5 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS13490 ff036588869965b55fede54e3710d474 211 Pfam PF08238 Sel1 repeat 76 106 0.0085 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS13490 ff036588869965b55fede54e3710d474 211 SMART SM00671 108 143 8.1E-6 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS13490 ff036588869965b55fede54e3710d474 211 SMART SM00671 144 179 31.0 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS13490 ff036588869965b55fede54e3710d474 211 SMART SM00671 72 107 0.0027 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS13490 ff036588869965b55fede54e3710d474 211 Gene3D G3DSA:1.25.40.10 72 178 1.9E-18 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS13490 ff036588869965b55fede54e3710d474 211 SUPERFAMILY SSF81901 65 177 3.79E-21 T 05-07-2017 K08M4_RS20565 12afa64a1f3e15922a9930e03192b497 210 Gene3D G3DSA:3.40.30.10 8 75 1.9E-23 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS20565 12afa64a1f3e15922a9930e03192b497 210 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 74 3.8E-13 T 05-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 K08M4_RS20565 12afa64a1f3e15922a9930e03192b497 210 Gene3D G3DSA:1.20.1050.10 91 209 5.3E-27 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS20565 12afa64a1f3e15922a9930e03192b497 210 Pfam PF04399 Glutaredoxin 2, C terminal domain 89 209 4.6E-26 T 05-07-2017 IPR007494 Glutaredoxin 2, C-terminal K08M4_RS20565 12afa64a1f3e15922a9930e03192b497 210 SUPERFAMILY SSF47616 78 209 6.19E-23 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS20565 12afa64a1f3e15922a9930e03192b497 210 SUPERFAMILY SSF52833 1 70 2.53E-17 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS18975 105da063dce74525939c40e7423f5409 430 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 231 247 - T 05-07-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 K08M4_RS18975 105da063dce74525939c40e7423f5409 430 Gene3D G3DSA:3.90.1150.10 293 429 1.3E-53 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS18975 105da063dce74525939c40e7423f5409 430 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 16 430 52.756 T 05-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 K08M4_RS18975 105da063dce74525939c40e7423f5409 430 Gene3D G3DSA:3.40.640.10 46 292 6.2E-105 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS18975 105da063dce74525939c40e7423f5409 430 SUPERFAMILY SSF53383 7 429 1.67E-179 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS18975 105da063dce74525939c40e7423f5409 430 Pfam PF00464 Serine hydroxymethyltransferase 18 394 9.1E-174 T 05-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 K08M4_RS18975 105da063dce74525939c40e7423f5409 430 PIRSF PIRSF000412 5 430 2.2E-168 T 05-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 K08M4_RS18460 3620e4e7ef4790c1744b96427a05f64b 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 217 2.5E-22 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS18460 3620e4e7ef4790c1744b96427a05f64b 232 Gene3D G3DSA:1.10.3720.10 9 227 5.3E-46 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS18460 3620e4e7ef4790c1744b96427a05f64b 232 SUPERFAMILY SSF161098 8 220 9.42E-51 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS18460 3620e4e7ef4790c1744b96427a05f64b 232 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 13 222 1.0E-74 T 05-07-2017 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 K08M4_RS18980 759402bfc1f539e0162b5753ae5c446a 126 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 2 124 30.813 T 05-07-2017 IPR002930 Glycine cleavage system H-protein K08M4_RS18980 759402bfc1f539e0162b5753ae5c446a 126 Pfam PF01597 Glycine cleavage H-protein 5 125 2.4E-49 T 05-07-2017 IPR002930 Glycine cleavage system H-protein K08M4_RS18980 759402bfc1f539e0162b5753ae5c446a 126 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 126 1.5E-50 T 05-07-2017 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 K08M4_RS18980 759402bfc1f539e0162b5753ae5c446a 126 SUPERFAMILY SSF51230 3 125 9.74E-44 T 05-07-2017 IPR011053 Single hybrid motif K08M4_RS18980 759402bfc1f539e0162b5753ae5c446a 126 Gene3D G3DSA:2.40.50.100 4 125 2.0E-49 T 05-07-2017 K08M4_RS18980 759402bfc1f539e0162b5753ae5c446a 126 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 46 75 - T 05-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 K08M4_RS19515 0da30462ab6d3c0553ff5d03052a3911 883 Pfam PF01568 Molydopterin dinucleotide binding domain 685 750 9.4E-13 T 05-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 K08M4_RS19515 0da30462ab6d3c0553ff5d03052a3911 883 Pfam PF01568 Molydopterin dinucleotide binding domain 615 661 4.4E-8 T 05-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 K08M4_RS19515 0da30462ab6d3c0553ff5d03052a3911 883 SUPERFAMILY SSF50692 685 780 3.16E-16 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain K08M4_RS19515 0da30462ab6d3c0553ff5d03052a3911 883 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 13 63 7.2E-16 T 05-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS19515 0da30462ab6d3c0553ff5d03052a3911 883 Gene3D G3DSA:2.40.40.20 607 756 5.5E-41 T 05-07-2017 K08M4_RS19515 0da30462ab6d3c0553ff5d03052a3911 883 SUPERFAMILY SSF50692 578 661 4.29E-17 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain K08M4_RS19515 0da30462ab6d3c0553ff5d03052a3911 883 Pfam PF00384 Molybdopterin oxidoreductase 81 512 1.1E-78 T 05-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS19515 0da30462ab6d3c0553ff5d03052a3911 883 Gene3D G3DSA:3.40.228.10 144 346 2.4E-54 T 05-07-2017 K08M4_RS19515 0da30462ab6d3c0553ff5d03052a3911 883 Gene3D G3DSA:2.20.25.90 13 63 1.9E-16 T 05-07-2017 K08M4_RS19515 0da30462ab6d3c0553ff5d03052a3911 883 SUPERFAMILY SSF53706 13 602 9.16E-178 T 05-07-2017 K08M4_RS19515 0da30462ab6d3c0553ff5d03052a3911 883 Gene3D G3DSA:3.40.50.740 68 143 2.5E-89 T 05-07-2017 K08M4_RS19515 0da30462ab6d3c0553ff5d03052a3911 883 Gene3D G3DSA:3.40.50.740 347 598 2.5E-89 T 05-07-2017 K08M4_RS19515 0da30462ab6d3c0553ff5d03052a3911 883 SMART SM00926 11 65 2.2E-13 T 05-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS03230 b52d96d486dccc5f89c8871e5ce3f510 258 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 11 230 9.6E-81 T 05-07-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 K08M4_RS03230 b52d96d486dccc5f89c8871e5ce3f510 258 SMART SM01133 10 244 2.7E-77 T 05-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 K08M4_RS03230 b52d96d486dccc5f89c8871e5ce3f510 258 Gene3D G3DSA:3.20.20.70 3 250 1.5E-91 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS03230 b52d96d486dccc5f89c8871e5ce3f510 258 PIRSF PIRSF001357 5 252 2.1E-76 T 05-07-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 K08M4_RS03230 b52d96d486dccc5f89c8871e5ce3f510 258 SUPERFAMILY SSF51569 6 245 2.62E-81 T 05-07-2017 K08M4_RS03230 b52d96d486dccc5f89c8871e5ce3f510 258 Hamap MF_00592 Deoxyribose-phosphate aldolase [deoC]. 1 258 51.641 T 05-07-2017 IPR023649 Deoxyribose-phosphate aldolase type II GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 K08M4_RS03230 b52d96d486dccc5f89c8871e5ce3f510 258 Pfam PF01791 DeoC/LacD family aldolase 11 239 1.3E-46 T 05-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 K08M4_RS13050 806c91de2767c7cf3b9f2c4d337f4faf 320 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 28 319 7.4E-22 T 05-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 K08M4_RS13050 806c91de2767c7cf3b9f2c4d337f4faf 320 SUPERFAMILY SSF52283 3 139 1.13E-31 T 05-07-2017 K08M4_RS13050 806c91de2767c7cf3b9f2c4d337f4faf 320 SUPERFAMILY SSF51735 103 290 2.82E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13050 806c91de2767c7cf3b9f2c4d337f4faf 320 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 289 4.5E-54 T 05-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 K08M4_RS13050 806c91de2767c7cf3b9f2c4d337f4faf 320 Gene3D G3DSA:3.40.50.720 2 111 3.9E-27 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13050 806c91de2767c7cf3b9f2c4d337f4faf 320 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 196 218 - T 05-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site K08M4_RS13050 806c91de2767c7cf3b9f2c4d337f4faf 320 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 225 241 - T 05-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site K08M4_RS13050 806c91de2767c7cf3b9f2c4d337f4faf 320 Gene3D G3DSA:3.40.50.720 112 290 5.6E-60 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS16170 5466bc175f0f467a1f1ed6974524a76d 320 Gene3D G3DSA:3.40.190.10 130 175 2.1E-5 T 05-07-2017 K08M4_RS16170 5466bc175f0f467a1f1ed6974524a76d 320 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 42 299 1.4E-52 T 05-07-2017 K08M4_RS16170 5466bc175f0f467a1f1ed6974524a76d 320 SUPERFAMILY SSF53850 39 284 1.09E-29 T 05-07-2017 K08M4_RS11755 3ae5b18f94afd4faf80bfa848fa448e9 242 Pfam PF04250 Protein of unknown function (DUF429) 5 208 1.4E-42 T 05-07-2017 IPR007362 Protein of unknown function DUF429 K08M4_RS04755 60d0b98a05cc7d1dba85fd843a88572b 602 Gene3D G3DSA:3.40.720.10 259 534 2.6E-28 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 K08M4_RS04755 60d0b98a05cc7d1dba85fd843a88572b 602 PIRSF PIRSF004950 6 600 6.5E-230 T 05-07-2017 IPR012159 Inner membrane protein YejM K08M4_RS04755 60d0b98a05cc7d1dba85fd843a88572b 602 Pfam PF00884 Sulfatase 278 515 7.0E-18 T 05-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 K08M4_RS04755 60d0b98a05cc7d1dba85fd843a88572b 602 Pfam PF11893 Domain of unknown function (DUF3413) 6 251 1.3E-99 T 05-07-2017 IPR024588 Inner membrane protein YejM, N-terminal K08M4_RS04755 60d0b98a05cc7d1dba85fd843a88572b 602 SUPERFAMILY SSF53649 258 582 4.51E-41 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 K08M4_RS02560 1398fd7501d40a171062c08d30befda1 164 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 12 155 5.3E-46 T 05-07-2017 IPR008136 CinA, C-terminal K08M4_RS02560 1398fd7501d40a171062c08d30befda1 164 SUPERFAMILY SSF142433 5 159 1.96E-54 T 05-07-2017 IPR008136 CinA, C-terminal K08M4_RS02560 1398fd7501d40a171062c08d30befda1 164 Gene3D G3DSA:3.90.950.20 3 160 1.0E-55 T 05-07-2017 IPR008136 CinA, C-terminal K08M4_RS02560 1398fd7501d40a171062c08d30befda1 164 Pfam PF02464 Competence-damaged protein 5 158 1.1E-56 T 05-07-2017 IPR008136 CinA, C-terminal K08M4_RS02760 c10a89686baa705fa5ddbaf0306319af 246 Gene3D G3DSA:3.40.1280.10 1 160 2.8E-68 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal K08M4_RS02760 c10a89686baa705fa5ddbaf0306319af 246 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 246 117.769 T 05-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 K08M4_RS02760 c10a89686baa705fa5ddbaf0306319af 246 Gene3D G3DSA:1.10.1270.20 163 244 1.1E-34 T 05-07-2017 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 K08M4_RS02760 c10a89686baa705fa5ddbaf0306319af 246 PIRSF PIRSF000386 1 245 2.5E-100 T 05-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 K08M4_RS02760 c10a89686baa705fa5ddbaf0306319af 246 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 234 1.4E-107 T 05-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 K08M4_RS02760 c10a89686baa705fa5ddbaf0306319af 246 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 7.7E-69 T 05-07-2017 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 K08M4_RS02760 c10a89686baa705fa5ddbaf0306319af 246 SUPERFAMILY SSF75217 1 243 6.21E-102 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases K08M4_RS18320 b57f5896898204eb6be8b3fbc9171664 131 Pfam PF11756 Nitrous oxide-stimulated promoter 12 116 1.1E-44 T 05-07-2017 IPR020483 Uncharacterised protein family YgbA K08M4_RS18320 b57f5896898204eb6be8b3fbc9171664 131 ProDom PD075772 YGBA ECS3588 CYTOPLASMIC UVRA STM2860 AMIDOPHOSPHORIBOSYLTRANSFERASE VVA0912 SO0324 VPA0976 CPE0229 11 107 6.0E-39 T 05-07-2017 IPR020483 Uncharacterised protein family YgbA K08M4_RS06265 c107300ef402789deac6f23e2c721ae7 490 PIRSF PIRSF001386 3 472 6.3E-204 T 05-07-2017 IPR011166 Beta-eliminating lyase family GO:0009072|GO:0016830 KEGG: 00380+4.1.99.1 K08M4_RS06265 c107300ef402789deac6f23e2c721ae7 490 SUPERFAMILY SSF53383 6 471 4.25E-123 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS06265 c107300ef402789deac6f23e2c721ae7 490 Gene3D G3DSA:3.90.1150.10 311 470 1.7E-62 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS06265 c107300ef402789deac6f23e2c721ae7 490 Pfam PF01212 Beta-eliminating lyase 49 437 1.3E-88 T 05-07-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 K08M4_RS06265 c107300ef402789deac6f23e2c721ae7 490 Hamap MF_00544 Tryptophanase [tnaA]. 4 471 97.15 T 05-07-2017 IPR013440 Tryptophanase GO:0006568|GO:0009034 KEGG: 00380+4.1.99.1 K08M4_RS06265 c107300ef402789deac6f23e2c721ae7 490 TIGRFAM TIGR02617 tnaA_trp_ase: tryptophanase 5 471 3.7E-291 T 05-07-2017 IPR013440 Tryptophanase GO:0006568|GO:0009034 KEGG: 00380+4.1.99.1 K08M4_RS06265 c107300ef402789deac6f23e2c721ae7 490 ProSitePatterns PS00853 Beta-eliminating lyases pyridoxal-phosphate attachment site. 260 278 - T 05-07-2017 IPR018176 Tryptophanase, conserved site KEGG: 00380+4.1.99.1 K08M4_RS06265 c107300ef402789deac6f23e2c721ae7 490 Gene3D G3DSA:3.40.640.10 62 310 9.7E-85 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS13230 d5f3943e191418f765275f3a6964b8b7 455 SUPERFAMILY SSF55021 381 454 1.77E-14 T 05-07-2017 K08M4_RS13230 d5f3943e191418f765275f3a6964b8b7 455 ProSitePatterns PS00324 Aspartokinase signature. 12 20 - T 05-07-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS13230 d5f3943e191418f765275f3a6964b8b7 455 PIRSF PIRSF000726 9 455 5.4E-130 T 05-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS13230 d5f3943e191418f765275f3a6964b8b7 455 Gene3D G3DSA:3.40.1160.10 113 300 6.8E-59 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS13230 d5f3943e191418f765275f3a6964b8b7 455 Gene3D G3DSA:3.40.1160.10 12 59 6.8E-59 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS13230 d5f3943e191418f765275f3a6964b8b7 455 SUPERFAMILY SSF53633 12 299 4.06E-74 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS13230 d5f3943e191418f765275f3a6964b8b7 455 Pfam PF00696 Amino acid kinase family 12 284 1.6E-46 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS13230 d5f3943e191418f765275f3a6964b8b7 455 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 12 455 8.7E-122 T 05-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS13230 d5f3943e191418f765275f3a6964b8b7 455 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 12 455 2.9E-121 T 05-07-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS13230 d5f3943e191418f765275f3a6964b8b7 455 SUPERFAMILY SSF55021 304 399 3.29E-18 T 05-07-2017 K08M4_RS02425 f7538fcad0ade4551aca7ab015656939 192 Pfam PF08281 Sigma-70, region 4 135 181 4.3E-18 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02425 f7538fcad0ade4551aca7ab015656939 192 Pfam PF04542 Sigma-70 region 2 25 92 3.6E-18 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02425 f7538fcad0ade4551aca7ab015656939 192 Gene3D G3DSA:1.10.1740.10 2 110 2.6E-37 T 05-07-2017 K08M4_RS02425 f7538fcad0ade4551aca7ab015656939 192 Gene3D G3DSA:1.10.10.10 124 188 7.1E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS02425 f7538fcad0ade4551aca7ab015656939 192 SUPERFAMILY SSF88946 2 107 2.51E-32 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02425 f7538fcad0ade4551aca7ab015656939 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 185 7.4E-33 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02425 f7538fcad0ade4551aca7ab015656939 192 SUPERFAMILY SSF88659 124 185 1.42E-17 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02425 f7538fcad0ade4551aca7ab015656939 192 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 2 190 2.1E-103 T 05-07-2017 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02425 f7538fcad0ade4551aca7ab015656939 192 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 47 78 - T 05-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS09675 7cd4bff0ed556a031423ac28780943ae 227 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 176 4.5E-52 T 05-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 K08M4_RS09675 7cd4bff0ed556a031423ac28780943ae 227 SUPERFAMILY SSF52540 1 211 5.98E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09675 7cd4bff0ed556a031423ac28780943ae 227 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 212 29.058 T 05-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 K08M4_RS09675 7cd4bff0ed556a031423ac28780943ae 227 PIRSF PIRSF006755 1 226 2.7E-74 T 05-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 K08M4_RS09675 7cd4bff0ed556a031423ac28780943ae 227 Pfam PF13500 AAA domain 4 211 1.2E-36 T 05-07-2017 K08M4_RS09675 7cd4bff0ed556a031423ac28780943ae 227 Gene3D G3DSA:3.40.50.300 2 215 4.0E-77 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09550 7cd4bff0ed556a031423ac28780943ae 227 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 176 4.5E-52 T 05-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 K08M4_RS09550 7cd4bff0ed556a031423ac28780943ae 227 SUPERFAMILY SSF52540 1 211 5.98E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09550 7cd4bff0ed556a031423ac28780943ae 227 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 212 29.058 T 05-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 K08M4_RS09550 7cd4bff0ed556a031423ac28780943ae 227 PIRSF PIRSF006755 1 226 2.7E-74 T 05-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 K08M4_RS09550 7cd4bff0ed556a031423ac28780943ae 227 Pfam PF13500 AAA domain 4 211 1.2E-36 T 05-07-2017 K08M4_RS09550 7cd4bff0ed556a031423ac28780943ae 227 Gene3D G3DSA:3.40.50.300 2 215 4.0E-77 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12670 9a0a258b1f7740b03a3c206687c5e039 130 Gene3D G3DSA:3.30.230.10 4 130 2.8E-50 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup K08M4_RS12670 9a0a258b1f7740b03a3c206687c5e039 130 SUPERFAMILY SSF54211 5 130 1.67E-47 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS12670 9a0a258b1f7740b03a3c206687c5e039 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 05-07-2017 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 K08M4_RS12670 9a0a258b1f7740b03a3c206687c5e039 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 3.0E-46 T 05-07-2017 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 K08M4_RS12670 9a0a258b1f7740b03a3c206687c5e039 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 33.418 T 05-07-2017 IPR023035 Ribosomal protein S9, bacterial/plastid K08M4_RS13535 dcdba9879415690f4fe447c137a83b63 741 Pfam PF08676 MutL C terminal dimerisation domain 549 667 4.4E-25 T 05-07-2017 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 K08M4_RS13535 dcdba9879415690f4fe447c137a83b63 741 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 1 310 5.4E-101 T 05-07-2017 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 K08M4_RS13535 dcdba9879415690f4fe447c137a83b63 741 Gene3D G3DSA:3.30.230.10 218 327 6.5E-39 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup K08M4_RS13535 dcdba9879415690f4fe447c137a83b63 741 SUPERFAMILY SSF118116 548 740 2.62E-35 T 05-07-2017 K08M4_RS13535 dcdba9879415690f4fe447c137a83b63 741 SUPERFAMILY SSF54211 191 330 8.72E-37 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS13535 dcdba9879415690f4fe447c137a83b63 741 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 1 739 24.987 T 05-07-2017 IPR020667 DNA mismatch repair protein, MutL GO:0006298 K08M4_RS13535 dcdba9879415690f4fe447c137a83b63 741 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 93 99 - T 05-07-2017 IPR014762 DNA mismatch repair, conserved site K08M4_RS13535 dcdba9879415690f4fe447c137a83b63 741 SMART SM01340 212 330 2.1E-57 T 05-07-2017 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 K08M4_RS13535 dcdba9879415690f4fe447c137a83b63 741 Gene3D G3DSA:3.30.565.10 1 217 1.5E-75 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS13535 dcdba9879415690f4fe447c137a83b63 741 SUPERFAMILY SSF55874 1 206 6.42E-53 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS13535 dcdba9879415690f4fe447c137a83b63 741 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 212 328 5.0E-39 T 05-07-2017 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 K08M4_RS13535 dcdba9879415690f4fe447c137a83b63 741 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 119 7.7E-12 T 05-07-2017 K08M4_RS13535 dcdba9879415690f4fe447c137a83b63 741 SMART SM00853 552 700 1.1E-12 T 05-07-2017 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 K08M4_RS03480 9903a383499e96315996fdb228048f91 379 Gene3D G3DSA:3.40.1160.10 11 267 4.1E-57 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS03480 9903a383499e96315996fdb228048f91 379 Pfam PF00696 Amino acid kinase family 14 243 8.2E-43 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS03480 9903a383499e96315996fdb228048f91 379 SUPERFAMILY SSF53633 14 265 9.69E-65 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS03480 9903a383499e96315996fdb228048f91 379 ProSitePatterns PS00902 Glutamate 5-kinase signature. 216 233 - T 05-07-2017 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 K08M4_RS03480 9903a383499e96315996fdb228048f91 379 PRINTS PR00474 Glutamate 5-kinase family signature 218 238 3.5E-54 T 05-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 K08M4_RS03480 9903a383499e96315996fdb228048f91 379 PRINTS PR00474 Glutamate 5-kinase family signature 157 184 3.5E-54 T 05-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 K08M4_RS03480 9903a383499e96315996fdb228048f91 379 PRINTS PR00474 Glutamate 5-kinase family signature 51 65 3.5E-54 T 05-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 K08M4_RS03480 9903a383499e96315996fdb228048f91 379 PRINTS PR00474 Glutamate 5-kinase family signature 125 146 3.5E-54 T 05-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 K08M4_RS03480 9903a383499e96315996fdb228048f91 379 PRINTS PR00474 Glutamate 5-kinase family signature 85 113 3.5E-54 T 05-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 K08M4_RS03480 9903a383499e96315996fdb228048f91 379 SMART SM00359 286 369 9.1E-21 T 05-07-2017 IPR002478 PUA domain GO:0003723 K08M4_RS03480 9903a383499e96315996fdb228048f91 379 TIGRFAM TIGR01027 proB: glutamate 5-kinase 14 375 2.0E-148 T 05-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 K08M4_RS03480 9903a383499e96315996fdb228048f91 379 Gene3D G3DSA:2.30.130.10 284 375 1.4E-24 T 05-07-2017 IPR015947 PUA-like domain K08M4_RS03480 9903a383499e96315996fdb228048f91 379 SUPERFAMILY SSF88697 286 376 6.08E-25 T 05-07-2017 IPR015947 PUA-like domain K08M4_RS03480 9903a383499e96315996fdb228048f91 379 Pfam PF01472 PUA domain 286 360 2.5E-23 T 05-07-2017 IPR002478 PUA domain GO:0003723 K08M4_RS03480 9903a383499e96315996fdb228048f91 379 PIRSF PIRSF000729 9 378 7.1E-138 T 05-07-2017 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 K08M4_RS03480 9903a383499e96315996fdb228048f91 379 Hamap MF_00456 Glutamate 5-kinase [proB]. 14 267 35.953 T 05-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 K08M4_RS07695 c823cc014480dd40154100c8c7a07957 85 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 72 4.1E-15 T 05-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM K08M4_RS07695 c823cc014480dd40154100c8c7a07957 85 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 55 3.4E-10 T 05-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM K08M4_RS07695 c823cc014480dd40154100c8c7a07957 85 Gene3D G3DSA:3.40.1620.10 23 49 1.2E-6 T 05-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM K08M4_RS07695 c823cc014480dd40154100c8c7a07957 85 SUPERFAMILY SSF143120 1 75 4.27E-16 T 05-07-2017 K08M4_RS09465 909006cbdaa794e7af22dbb6517cac6e 216 SUPERFAMILY SSF101386 128 215 1.24E-25 T 05-07-2017 K08M4_RS09465 909006cbdaa794e7af22dbb6517cac6e 216 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 66 115 3.0E-22 T 05-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 K08M4_RS09465 909006cbdaa794e7af22dbb6517cac6e 216 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 18 216 37.455 T 05-07-2017 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 K08M4_RS09465 909006cbdaa794e7af22dbb6517cac6e 216 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 125 211 19.599 T 05-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 K08M4_RS09465 909006cbdaa794e7af22dbb6517cac6e 216 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 128 211 3.9E-32 T 05-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 K08M4_RS09465 909006cbdaa794e7af22dbb6517cac6e 216 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 128 215 1.8E-18 T 05-07-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 K08M4_RS09465 909006cbdaa794e7af22dbb6517cac6e 216 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 43 115 5.7E-31 T 05-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 K08M4_RS09465 909006cbdaa794e7af22dbb6517cac6e 216 SUPERFAMILY SSF141734 19 129 2.62E-44 T 05-07-2017 K08M4_RS08150 08b71363d9547052c33235e0da397ed9 148 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 11 89 2.7E-10 T 05-07-2017 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis K08M4_RS08150 08b71363d9547052c33235e0da397ed9 148 SUPERFAMILY SSF53146 1 117 4.45E-20 T 05-07-2017 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis K08M4_RS08150 08b71363d9547052c33235e0da397ed9 148 Gene3D G3DSA:3.30.420.130 1 88 1.6E-12 T 05-07-2017 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis K08M4_RS01165 352baf82ee081116fb286f7d04d92ca4 106 ProDom PD020365 REPRESSOR MET BIOSYNTHESIS TRANSCRIPTION METJ METHIONINE REGULON DNA-BINDING REGULATORY AMINO-ACID 10 101 2.0E-47 T 05-07-2017 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 K08M4_RS01165 352baf82ee081116fb286f7d04d92ca4 106 Hamap MF_00744 Met repressor [metJ]. 1 105 35.001 T 05-07-2017 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 K08M4_RS01165 352baf82ee081116fb286f7d04d92ca4 106 Pfam PF01340 Met Apo-repressor, MetJ 3 99 5.9E-60 T 05-07-2017 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 K08M4_RS01165 352baf82ee081116fb286f7d04d92ca4 106 Gene3D G3DSA:1.10.140.10 2 104 2.2E-63 T 05-07-2017 IPR023453 Methionine repressor MetJ domain K08M4_RS01165 352baf82ee081116fb286f7d04d92ca4 106 SUPERFAMILY SSF47598 3 104 4.22E-57 T 05-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 K08M4_RS17700 caefbf06d478118a66cbd2b00b411a2e 208 ProSitePatterns PS00194 Thioredoxin family active site. 48 66 - T 05-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 K08M4_RS17700 caefbf06d478118a66cbd2b00b411a2e 208 SUPERFAMILY SSF52833 48 205 1.29E-23 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS17700 caefbf06d478118a66cbd2b00b411a2e 208 Pfam PF13462 Thioredoxin 49 201 3.0E-7 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS17700 caefbf06d478118a66cbd2b00b411a2e 208 Gene3D G3DSA:3.40.30.10 25 207 1.4E-43 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS01865 8f8adf9be512fb90fb2633e3cb7d5939 102 Pfam PF13466 STAS domain 16 92 3.6E-18 T 05-07-2017 IPR002645 STAS domain K08M4_RS01865 8f8adf9be512fb90fb2633e3cb7d5939 102 SUPERFAMILY SSF52091 11 96 3.73E-17 T 05-07-2017 IPR002645 STAS domain K08M4_RS01865 8f8adf9be512fb90fb2633e3cb7d5939 102 Gene3D G3DSA:3.30.750.24 14 94 6.2E-15 T 05-07-2017 IPR002645 STAS domain K08M4_RS12810 3de9ac2028ae3186f047de0cd52dbe2e 271 PRINTS PR00412 Epoxide hydrolase signature 45 60 8.6E-7 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 K08M4_RS12810 3de9ac2028ae3186f047de0cd52dbe2e 271 PRINTS PR00412 Epoxide hydrolase signature 104 117 8.6E-7 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 K08M4_RS12810 3de9ac2028ae3186f047de0cd52dbe2e 271 PRINTS PR00412 Epoxide hydrolase signature 243 265 8.6E-7 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 K08M4_RS12810 3de9ac2028ae3186f047de0cd52dbe2e 271 Gene3D G3DSA:3.40.50.1820 2 267 2.5E-55 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS12810 3de9ac2028ae3186f047de0cd52dbe2e 271 SUPERFAMILY SSF53474 2 268 2.55E-57 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS12810 3de9ac2028ae3186f047de0cd52dbe2e 271 Pfam PF12697 Alpha/beta hydrolase family 23 258 6.1E-14 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS12810 3de9ac2028ae3186f047de0cd52dbe2e 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 2.6E-6 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS12810 3de9ac2028ae3186f047de0cd52dbe2e 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 2.6E-6 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS12810 3de9ac2028ae3186f047de0cd52dbe2e 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 2.6E-6 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS12810 3de9ac2028ae3186f047de0cd52dbe2e 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 212 226 2.6E-6 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS08245 353778e27bfab91a52a9fac93dbf0654 502 Pfam PF11840 Protein of unknown function (DUF3360) 16 498 1.9E-269 T 05-07-2017 IPR021794 Protein of unknown function DUF3360 K08M4_RS19200 2d72206b202af35e51e46b0ed3e94c85 350 Gene3D G3DSA:2.40.160.10 97 323 1.2E-10 T 05-07-2017 IPR023614 Porin domain K08M4_RS19200 2d72206b202af35e51e46b0ed3e94c85 350 SUPERFAMILY SSF56935 26 350 2.31E-26 T 05-07-2017 K08M4_RS11230 7a0f80768c19785ea2453b57dcdf4a8d 254 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 13 236 41.399 T 05-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 K08M4_RS11230 7a0f80768c19785ea2453b57dcdf4a8d 254 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 17 28 - T 05-07-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 K08M4_RS11230 7a0f80768c19785ea2453b57dcdf4a8d 254 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 169 193 - T 05-07-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 K08M4_RS11230 7a0f80768c19785ea2453b57dcdf4a8d 254 SUPERFAMILY SSF52313 17 241 1.57E-95 T 05-07-2017 IPR023591 Ribosomal protein S2, flavodoxin-like domain K08M4_RS11230 7a0f80768c19785ea2453b57dcdf4a8d 254 PRINTS PR00395 Ribosomal protein S2 signature 207 221 4.1E-37 T 05-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS11230 7a0f80768c19785ea2453b57dcdf4a8d 254 PRINTS PR00395 Ribosomal protein S2 signature 186 197 4.1E-37 T 05-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS11230 7a0f80768c19785ea2453b57dcdf4a8d 254 PRINTS PR00395 Ribosomal protein S2 signature 48 57 4.1E-37 T 05-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS11230 7a0f80768c19785ea2453b57dcdf4a8d 254 PRINTS PR00395 Ribosomal protein S2 signature 98 115 4.1E-37 T 05-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS11230 7a0f80768c19785ea2453b57dcdf4a8d 254 PRINTS PR00395 Ribosomal protein S2 signature 169 186 4.1E-37 T 05-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS11230 7a0f80768c19785ea2453b57dcdf4a8d 254 PRINTS PR00395 Ribosomal protein S2 signature 17 35 4.1E-37 T 05-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS11230 7a0f80768c19785ea2453b57dcdf4a8d 254 Gene3D G3DSA:1.10.287.610 111 163 1.1E-26 T 05-07-2017 K08M4_RS11230 7a0f80768c19785ea2453b57dcdf4a8d 254 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 14 237 7.5E-109 T 05-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 K08M4_RS11230 7a0f80768c19785ea2453b57dcdf4a8d 254 Gene3D G3DSA:3.40.50.10490 169 243 3.0E-65 T 05-07-2017 K08M4_RS11230 7a0f80768c19785ea2453b57dcdf4a8d 254 Gene3D G3DSA:3.40.50.10490 34 110 3.0E-65 T 05-07-2017 K08M4_RS11230 7a0f80768c19785ea2453b57dcdf4a8d 254 Pfam PF00318 Ribosomal protein S2 20 235 1.2E-94 T 05-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS11565 4dda271f0265dd68a16b5e1fb485aed6 445 Gene3D G3DSA:3.40.630.30 298 441 3.0E-41 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS11565 4dda271f0265dd68a16b5e1fb485aed6 445 Gene3D G3DSA:3.40.1160.10 23 294 6.2E-68 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS11565 4dda271f0265dd68a16b5e1fb485aed6 445 Pfam PF00696 Amino acid kinase family 25 271 1.7E-27 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS11565 4dda271f0265dd68a16b5e1fb485aed6 445 Pfam PF00583 Acetyltransferase (GNAT) family 344 416 6.4E-6 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS11565 4dda271f0265dd68a16b5e1fb485aed6 445 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 8 443 2.1E-203 T 05-07-2017 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 K08M4_RS11565 4dda271f0265dd68a16b5e1fb485aed6 445 SUPERFAMILY SSF55729 300 426 8.06E-19 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS11565 4dda271f0265dd68a16b5e1fb485aed6 445 PIRSF PIRSF000423 1 445 3.9E-204 T 05-07-2017 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 K08M4_RS11565 4dda271f0265dd68a16b5e1fb485aed6 445 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 445 224.493 T 05-07-2017 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 K08M4_RS11565 4dda271f0265dd68a16b5e1fb485aed6 445 SUPERFAMILY SSF53633 5 294 2.65E-70 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS00940 ffb2416a7c27ef18d22696676e6982f5 210 SMART SM00479 29 203 1.4E-21 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS00940 ffb2416a7c27ef18d22696676e6982f5 210 Pfam PF00929 Exonuclease 31 194 1.8E-16 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS00940 ffb2416a7c27ef18d22696676e6982f5 210 Gene3D G3DSA:3.30.420.10 27 199 7.3E-31 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS00940 ffb2416a7c27ef18d22696676e6982f5 210 SUPERFAMILY SSF53098 29 199 1.48E-30 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 ProSitePatterns PS00177 DNA topoisomerase II signature. 423 431 - T 05-07-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 SUPERFAMILY SSF56719 395 561 4.45E-88 T 05-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 SUPERFAMILY SSF56719 731 796 4.45E-88 T 05-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 Gene3D G3DSA:3.40.50.670 405 551 3.0E-101 T 05-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 Gene3D G3DSA:3.40.50.670 719 787 3.0E-101 T 05-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 SMART SM00433 35 798 5.2E-271 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 174 1.4E-23 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 5 805 0.0 T 05-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 Pfam PF01751 Toprim domain 420 532 1.0E-18 T 05-07-2017 IPR006171 Toprim domain K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR01159 DNA gyrase subunit B signature 313 329 3.4E-84 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR01159 DNA gyrase subunit B signature 375 395 3.4E-84 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR01159 DNA gyrase subunit B signature 774 790 3.4E-84 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR01159 DNA gyrase subunit B signature 195 208 3.4E-84 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR01159 DNA gyrase subunit B signature 5 15 3.4E-84 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR01159 DNA gyrase subunit B signature 180 195 3.4E-84 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR01159 DNA gyrase subunit B signature 471 480 3.4E-84 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR01159 DNA gyrase subunit B signature 758 770 3.4E-84 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR01159 DNA gyrase subunit B signature 220 242 3.4E-84 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR01159 DNA gyrase subunit B signature 243 261 3.4E-84 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR01159 DNA gyrase subunit B signature 361 375 3.4E-84 T 05-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR00418 DNA topoisomerase II family signature 35 50 3.7E-70 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR00418 DNA topoisomerase II family signature 113 127 3.7E-70 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR00418 DNA topoisomerase II family signature 737 753 3.7E-70 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR00418 DNA topoisomerase II family signature 488 504 3.7E-70 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR00418 DNA topoisomerase II family signature 506 523 3.7E-70 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR00418 DNA topoisomerase II family signature 70 83 3.7E-70 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR00418 DNA topoisomerase II family signature 526 538 3.7E-70 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR00418 DNA topoisomerase II family signature 269 282 3.7E-70 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 PRINTS PR00418 DNA topoisomerase II family signature 421 435 3.7E-70 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 2 805 107.463 T 05-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 SMART SM00387 31 175 7.0E-27 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 Pfam PF00204 DNA gyrase B 221 391 3.0E-59 T 05-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 734 794 1.7E-29 T 05-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 SUPERFAMILY SSF55874 4 212 1.1E-74 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 SUPERFAMILY SSF54211 221 393 9.86E-58 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 Gene3D G3DSA:3.30.230.10 220 393 7.1E-75 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup K08M4_RS00020 f78e164759ef2e3e431c97df2e8dba70 805 Gene3D G3DSA:3.30.565.10 15 213 1.2E-92 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08170 a31af57795e0798e7b267cc8ad9dd632 335 SUPERFAMILY SSF81901 65 304 1.64E-43 T 05-07-2017 K08M4_RS08170 a31af57795e0798e7b267cc8ad9dd632 335 Gene3D G3DSA:1.25.40.10 50 315 2.6E-56 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS08170 a31af57795e0798e7b267cc8ad9dd632 335 SMART SM00671 266 301 0.25 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS08170 a31af57795e0798e7b267cc8ad9dd632 335 SMART SM00671 224 265 8.1 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS08170 a31af57795e0798e7b267cc8ad9dd632 335 SMART SM00671 115 150 4.7E-5 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS08170 a31af57795e0798e7b267cc8ad9dd632 335 SMART SM00671 151 186 2.0E-8 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS08170 a31af57795e0798e7b267cc8ad9dd632 335 SMART SM00671 187 222 1.9E-6 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS08170 a31af57795e0798e7b267cc8ad9dd632 335 SMART SM00671 83 114 17.0 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS08170 a31af57795e0798e7b267cc8ad9dd632 335 Pfam PF08238 Sel1 repeat 268 294 0.084 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS08170 a31af57795e0798e7b267cc8ad9dd632 335 Pfam PF08238 Sel1 repeat 187 220 6.1E-6 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS08170 a31af57795e0798e7b267cc8ad9dd632 335 Pfam PF08238 Sel1 repeat 247 265 0.007 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS08170 a31af57795e0798e7b267cc8ad9dd632 335 Pfam PF08238 Sel1 repeat 118 150 0.0042 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS08170 a31af57795e0798e7b267cc8ad9dd632 335 Pfam PF08238 Sel1 repeat 99 109 41.0 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS08170 a31af57795e0798e7b267cc8ad9dd632 335 Pfam PF08238 Sel1 repeat 151 186 3.3E-8 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 Gene3D G3DSA:1.10.150.20 357 420 6.2E-22 T 05-07-2017 K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 342 2.1E-122 T 05-07-2017 IPR010213 Transcription termination factor NusA GO:0003723 K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 410 28.481 T 05-07-2017 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 SUPERFAMILY SSF54814 201 278 7.19E-28 T 05-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 SUPERFAMILY SSF50249 132 199 1.08E-16 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 SUPERFAMILY SSF47794 356 415 2.2E-16 T 05-07-2017 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 Gene3D G3DSA:3.30.300.20 278 347 1.6E-27 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 SUPERFAMILY SSF54814 279 342 5.67E-15 T 05-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 Gene3D G3DSA:2.40.50.140 128 197 8.7E-23 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 SMART SM00316 133 200 8.3E-6 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 Pfam PF08529 NusA N-terminal domain 4 123 1.8E-34 T 05-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 Pfam PF14520 Helix-hairpin-helix domain 432 486 3.8E-7 T 05-07-2017 K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 SUPERFAMILY SSF47794 429 492 1.49E-15 T 05-07-2017 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 440 489 1.1E-16 T 05-07-2017 IPR010214 Transcription termination factor NusA, C-terminal duplication K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 365 414 2.6E-21 T 05-07-2017 IPR010214 Transcription termination factor NusA, C-terminal duplication K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 Gene3D G3DSA:3.30.300.20 199 277 7.6E-33 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 Gene3D G3DSA:1.10.150.20 432 490 5.6E-22 T 05-07-2017 K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 SUPERFAMILY SSF69705 1 126 1.16E-38 T 05-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 Pfam PF13184 NusA-like KH domain 230 297 2.9E-27 T 05-07-2017 IPR025249 KH domain, NusA-like GO:0003723 K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 Gene3D G3DSA:3.30.1480.10 1 124 2.1E-43 T 05-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 SMART SM00322 301 375 0.097 T 05-07-2017 IPR004087 K Homology domain GO:0003676 K08M4_RS03120 282dc75365e930e8f28d6b4104efce6b 495 SMART SM00322 230 293 15.0 T 05-07-2017 IPR004087 K Homology domain GO:0003676 K08M4_RS17170 7db69375be15c0bf1256dd4cde6d6c7d 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.9E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS17170 7db69375be15c0bf1256dd4cde6d6c7d 292 Pfam PF03466 LysR substrate binding domain 111 287 3.1E-13 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS17170 7db69375be15c0bf1256dd4cde6d6c7d 292 Gene3D G3DSA:1.10.10.10 1 80 8.6E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS17170 7db69375be15c0bf1256dd4cde6d6c7d 292 Gene3D G3DSA:3.40.190.10 106 195 1.2E-8 T 05-07-2017 K08M4_RS17170 7db69375be15c0bf1256dd4cde6d6c7d 292 SUPERFAMILY SSF46785 1 84 1.95E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS17170 7db69375be15c0bf1256dd4cde6d6c7d 292 SUPERFAMILY SSF53850 96 287 4.89E-19 T 05-07-2017 K08M4_RS07835 ebeab8d8d83bb7f59bb32dd133619797 207 Pfam PF04352 ProQ/FINO family 8 115 4.8E-43 T 05-07-2017 IPR016103 ProQ/FinO domain K08M4_RS07835 ebeab8d8d83bb7f59bb32dd133619797 207 Hamap MF_00749 RNA chaperone ProQ [proQ]. 3 207 29.831 T 05-07-2017 IPR023529 RNA chaperone ProQ GO:0003723|GO:0010608|GO:0033592|GO:0034057 K08M4_RS07835 ebeab8d8d83bb7f59bb32dd133619797 207 SUPERFAMILY SSF48657 5 119 1.31E-39 T 05-07-2017 IPR016103 ProQ/FinO domain K08M4_RS07835 ebeab8d8d83bb7f59bb32dd133619797 207 Gene3D G3DSA:1.10.1710.10 3 118 1.6E-37 T 05-07-2017 IPR016103 ProQ/FinO domain K08M4_RS07835 ebeab8d8d83bb7f59bb32dd133619797 207 SMART SM00945 5 119 4.2E-64 T 05-07-2017 IPR016103 ProQ/FinO domain K08M4_RS18620 dfb9adac2330b56c0cc1c539a4b98241 224 SUPERFAMILY SSF52540 5 223 1.21E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18620 dfb9adac2330b56c0cc1c539a4b98241 224 Pfam PF00005 ABC transporter 25 171 1.9E-34 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS18620 dfb9adac2330b56c0cc1c539a4b98241 224 SMART SM00382 34 222 1.7E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS18620 dfb9adac2330b56c0cc1c539a4b98241 224 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS18620 dfb9adac2330b56c0cc1c539a4b98241 224 Gene3D G3DSA:3.40.50.300 5 223 3.4E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12280 5a8b036a03a1fdd193b03fdeaac39a39 273 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 257 1.1E-83 T 05-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 K08M4_RS12280 5a8b036a03a1fdd193b03fdeaac39a39 273 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 6 262 8.9E-91 T 05-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 K08M4_RS12280 5a8b036a03a1fdd193b03fdeaac39a39 273 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 10 262 20.2 T 05-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 K08M4_RS12280 5a8b036a03a1fdd193b03fdeaac39a39 273 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 142 154 - T 05-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 K08M4_RS03485 ef5805f49a5d284075ba33c8c7bdc37f 416 Gene3D G3DSA:3.40.605.10 374 414 1.6E-98 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS03485 ef5805f49a5d284075ba33c8c7bdc37f 416 Gene3D G3DSA:3.40.605.10 3 221 1.6E-98 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS03485 ef5805f49a5d284075ba33c8c7bdc37f 416 PIRSF PIRSF000151 1 416 6.4E-165 T 05-07-2017 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 K08M4_RS03485 ef5805f49a5d284075ba33c8c7bdc37f 416 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 322 343 - T 05-07-2017 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 K08M4_RS03485 ef5805f49a5d284075ba33c8c7bdc37f 416 Gene3D G3DSA:3.40.309.10 224 373 3.4E-34 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 K08M4_RS03485 ef5805f49a5d284075ba33c8c7bdc37f 416 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 10 405 3.9E-167 T 05-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 K08M4_RS03485 ef5805f49a5d284075ba33c8c7bdc37f 416 Pfam PF00171 Aldehyde dehydrogenase family 9 279 7.6E-16 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS03485 ef5805f49a5d284075ba33c8c7bdc37f 416 SUPERFAMILY SSF53720 5 409 7.33E-111 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 K08M4_RS03485 ef5805f49a5d284075ba33c8c7bdc37f 416 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 2 415 39.393 T 05-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 K08M4_RS08085 c90ad35ca701a8a2925569e91c1d243a 501 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 7 487 9.8E-202 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 K08M4_RS08085 c90ad35ca701a8a2925569e91c1d243a 501 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 194 487 2.6E-115 T 05-07-2017 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 K08M4_RS08085 c90ad35ca701a8a2925569e91c1d243a 501 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 11 192 9.9E-65 T 05-07-2017 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 K08M4_RS08085 c90ad35ca701a8a2925569e91c1d243a 501 SUPERFAMILY SSF51735 4 195 4.33E-64 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS08085 c90ad35ca701a8a2925569e91c1d243a 501 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 224 241 3.0E-49 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 K08M4_RS08085 c90ad35ca701a8a2925569e91c1d243a 501 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 242 258 3.0E-49 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 K08M4_RS08085 c90ad35ca701a8a2925569e91c1d243a 501 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 148 161 3.0E-49 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 K08M4_RS08085 c90ad35ca701a8a2925569e91c1d243a 501 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 172 200 3.0E-49 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 K08M4_RS08085 c90ad35ca701a8a2925569e91c1d243a 501 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 333 359 3.0E-49 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 K08M4_RS08085 c90ad35ca701a8a2925569e91c1d243a 501 PIRSF PIRSF000110 2 490 1.9E-180 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 K08M4_RS08085 c90ad35ca701a8a2925569e91c1d243a 501 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 7 488 86.148 T 05-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 K08M4_RS08085 c90ad35ca701a8a2925569e91c1d243a 501 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 182 188 - T 05-07-2017 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 K08M4_RS08085 c90ad35ca701a8a2925569e91c1d243a 501 Gene3D G3DSA:3.30.360.10 192 487 1.4E-121 T 05-07-2017 K08M4_RS08085 c90ad35ca701a8a2925569e91c1d243a 501 Gene3D G3DSA:3.40.50.720 6 191 1.3E-72 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS08085 c90ad35ca701a8a2925569e91c1d243a 501 SUPERFAMILY SSF55347 182 490 2.91E-114 T 05-07-2017 K08M4_RS21815 c078d30a25a31ad0fe78c51279bbf3de 234 Gene3D G3DSA:3.40.30.10 12 87 1.9E-23 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS21815 c078d30a25a31ad0fe78c51279bbf3de 234 SUPERFAMILY SSF47616 96 229 1.89E-22 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS21815 c078d30a25a31ad0fe78c51279bbf3de 234 Pfam PF13417 Glutathione S-transferase, N-terminal domain 12 88 1.1E-13 T 05-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 K08M4_RS21815 c078d30a25a31ad0fe78c51279bbf3de 234 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 11 230 1.8E-75 T 05-07-2017 IPR005955 Maleylacetoacetate isomerase GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 K08M4_RS21815 c078d30a25a31ad0fe78c51279bbf3de 234 SUPERFAMILY SSF52833 10 88 1.12E-18 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS21815 c078d30a25a31ad0fe78c51279bbf3de 234 Gene3D G3DSA:1.20.1050.10 99 231 6.7E-45 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS21565 82bc324cc6077669b0617025ca7aedd2 481 PRINTS PR00147 DNA photolyase signature 138 154 4.3E-29 T 05-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 K08M4_RS21565 82bc324cc6077669b0617025ca7aedd2 481 PRINTS PR00147 DNA photolyase signature 337 353 4.3E-29 T 05-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 K08M4_RS21565 82bc324cc6077669b0617025ca7aedd2 481 PRINTS PR00147 DNA photolyase signature 396 410 4.3E-29 T 05-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 K08M4_RS21565 82bc324cc6077669b0617025ca7aedd2 481 PRINTS PR00147 DNA photolyase signature 357 375 4.3E-29 T 05-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 K08M4_RS21565 82bc324cc6077669b0617025ca7aedd2 481 Gene3D G3DSA:1.25.40.80 143 157 1.3E-33 T 05-07-2017 K08M4_RS21565 82bc324cc6077669b0617025ca7aedd2 481 Gene3D G3DSA:1.25.40.80 214 295 1.3E-33 T 05-07-2017 K08M4_RS21565 82bc324cc6077669b0617025ca7aedd2 481 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 337 349 - T 05-07-2017 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal K08M4_RS21565 82bc324cc6077669b0617025ca7aedd2 481 SUPERFAMILY SSF52425 4 172 2.22E-47 T 05-07-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 K08M4_RS21565 82bc324cc6077669b0617025ca7aedd2 481 Gene3D G3DSA:1.10.579.10 296 480 1.5E-76 T 05-07-2017 K08M4_RS21565 82bc324cc6077669b0617025ca7aedd2 481 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 357 376 - T 05-07-2017 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal K08M4_RS21565 82bc324cc6077669b0617025ca7aedd2 481 Pfam PF03441 FAD binding domain of DNA photolyase 287 480 2.1E-82 T 05-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 K08M4_RS21565 82bc324cc6077669b0617025ca7aedd2 481 SUPERFAMILY SSF48173 203 480 2.35E-100 T 05-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 K08M4_RS21565 82bc324cc6077669b0617025ca7aedd2 481 Gene3D G3DSA:3.40.50.620 4 142 2.1E-37 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS21565 82bc324cc6077669b0617025ca7aedd2 481 Pfam PF00875 DNA photolyase 4 163 1.3E-37 T 05-07-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 K08M4_RS01265 c4d0a90e288416aebc966149edb1a98f 209 PIRSF PIRSF016482 8 209 1.7E-70 T 05-07-2017 IPR007445 Pilus assembly protein, PilO K08M4_RS01265 c4d0a90e288416aebc966149edb1a98f 209 Pfam PF04350 Pilus assembly protein, PilO 59 201 2.7E-47 T 05-07-2017 IPR007445 Pilus assembly protein, PilO K08M4_RS01265 c4d0a90e288416aebc966149edb1a98f 209 Gene3D G3DSA:3.30.70.60 104 206 8.5E-31 T 05-07-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 K08M4_RS17345 a9485be3302e00b078240ca0aa0554b9 490 Pfam PF03577 Peptidase family C69 23 412 2.0E-103 T 05-07-2017 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 K08M4_RS19605 f80f527eb990d1a013b5e149b5ab0e3d 151 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 12 131 36.013 T 05-07-2017 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 K08M4_RS19605 f80f527eb990d1a013b5e149b5ab0e3d 151 Gene3D G3DSA:3.40.50.1380 4 150 3.3E-64 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain K08M4_RS19605 f80f527eb990d1a013b5e149b5ab0e3d 151 Pfam PF02142 MGS-like domain 25 118 8.3E-19 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain K08M4_RS19605 f80f527eb990d1a013b5e149b5ab0e3d 151 SUPERFAMILY SSF52335 4 150 1.44E-58 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain K08M4_RS19605 f80f527eb990d1a013b5e149b5ab0e3d 151 ProSitePatterns PS01335 Methylglyoxal synthase active site. 65 73 - T 05-07-2017 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 K08M4_RS19605 f80f527eb990d1a013b5e149b5ab0e3d 151 SMART SM00851 25 118 3.1E-24 T 05-07-2017 IPR011607 Methylglyoxal synthase-like domain K08M4_RS19605 f80f527eb990d1a013b5e149b5ab0e3d 151 PIRSF PIRSF006614 8 151 5.6E-64 T 05-07-2017 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 K08M4_RS19605 f80f527eb990d1a013b5e149b5ab0e3d 151 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 11 150 2.1E-63 T 05-07-2017 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 K08M4_RS08645 846a071d154c4c93519cae122bc282cc 547 Gene3D G3DSA:3.90.1150.10 396 528 6.5E-37 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS08645 846a071d154c4c93519cae122bc282cc 547 SUPERFAMILY SSF53383 25 527 5.16E-112 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS08645 846a071d154c4c93519cae122bc282cc 547 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 63 442 7.9E-56 T 05-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 K08M4_RS08645 846a071d154c4c93519cae122bc282cc 547 Gene3D G3DSA:3.40.640.10 116 395 1.1E-83 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS08645 846a071d154c4c93519cae122bc282cc 547 TIGRFAM TIGR03799 NOD_PanD_pyr: putative pyridoxal-dependent aspartate 1-decarboxylase 6 527 1.2E-294 T 05-07-2017 IPR022517 Aspartate 1-decarboxylase, pyridoxal-dependent K08M4_RS10290 9dc869d27bddbba925d616c4c0872ef1 196 SUPERFAMILY SSF46689 9 78 4.03E-7 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS10290 9dc869d27bddbba925d616c4c0872ef1 196 Gene3D G3DSA:1.10.357.10 2 195 1.3E-30 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS10290 9dc869d27bddbba925d616c4c0872ef1 196 SUPERFAMILY SSF48498 83 195 2.47E-19 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal K08M4_RS10290 9dc869d27bddbba925d616c4c0872ef1 196 Pfam PF13305 WHG domain 92 172 5.7E-11 T 05-07-2017 IPR025996 WHG domain K08M4_RS11500 bd57edb56c4412b5cecf537d66f129de 102 SUPERFAMILY SSF82657 1 87 7.98E-32 T 05-07-2017 IPR002634 BolA protein K08M4_RS11500 bd57edb56c4412b5cecf537d66f129de 102 PIRSF PIRSF003113 1 99 1.5E-38 T 05-07-2017 IPR002634 BolA protein K08M4_RS11500 bd57edb56c4412b5cecf537d66f129de 102 Pfam PF01722 BolA-like protein 10 83 5.0E-32 T 05-07-2017 IPR002634 BolA protein K08M4_RS11500 bd57edb56c4412b5cecf537d66f129de 102 Gene3D G3DSA:3.30.300.90 1 101 6.5E-34 T 05-07-2017 IPR002634 BolA protein K08M4_RS10860 75dadb609a59252da794ea8cec3122ae 131 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 K08M4_RS10860 75dadb609a59252da794ea8cec3122ae 131 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 1 126 3.3E-52 T 05-07-2017 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 K08M4_RS10860 75dadb609a59252da794ea8cec3122ae 131 Pfam PF09278 MerR, DNA binding 46 107 4.7E-15 T 05-07-2017 IPR015358 Transcription regulator MerR, DNA binding K08M4_RS10860 75dadb609a59252da794ea8cec3122ae 131 Gene3D G3DSA:1.10.1660.10 56 129 1.4E-24 T 05-07-2017 K08M4_RS10860 75dadb609a59252da794ea8cec3122ae 131 SMART SM00422 1 70 2.3E-18 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 K08M4_RS10860 75dadb609a59252da794ea8cec3122ae 131 Pfam PF00376 MerR family regulatory protein 2 39 3.0E-12 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 K08M4_RS10860 75dadb609a59252da794ea8cec3122ae 131 Gene3D G3DSA:1.10.1660.10 1 55 2.9E-20 T 05-07-2017 K08M4_RS10860 75dadb609a59252da794ea8cec3122ae 131 SUPERFAMILY SSF46955 1 126 1.53E-31 T 05-07-2017 IPR009061 Putative DNA-binding domain K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 6 383 38.086 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 PRINTS PR00477 Phosphoglycerate kinase family signature 186 205 6.8E-81 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 6.8E-81 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 PRINTS PR00477 Phosphoglycerate kinase family signature 336 347 6.8E-81 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 PRINTS PR00477 Phosphoglycerate kinase family signature 359 376 6.8E-81 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 6.8E-81 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 6.8E-81 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 PRINTS PR00477 Phosphoglycerate kinase family signature 303 328 6.8E-81 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 PRINTS PR00477 Phosphoglycerate kinase family signature 104 119 6.8E-81 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 PRINTS PR00477 Phosphoglycerate kinase family signature 163 185 6.8E-81 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 05-07-2017 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 Gene3D G3DSA:3.40.50.1260 5 174 4.9E-64 T 05-07-2017 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 Gene3D G3DSA:3.40.50.1270 175 371 7.1E-79 T 05-07-2017 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 Pfam PF00162 Phosphoglycerate kinase 6 373 2.0E-136 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 SUPERFAMILY SSF53748 3 383 5.42E-144 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02325 236b3faf93b48d4b88d86015b8f3d696 387 PIRSF PIRSF000724 1 387 1.3E-132 T 05-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS14195 c7ee6c0427dc5b8f821473d6dfc35e4a 259 Pfam PF01203 Type II secretion system (T2SS), protein N 43 254 3.4E-59 T 05-07-2017 IPR022792 Type II secretion system, protein N K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 Gene3D G3DSA:3.80.10.10 4 192 5.6E-36 T 05-07-2017 IPR032675 Leucine-rich repeat domain, L domain-like K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 SUPERFAMILY SSF56112 202 371 1.23E-25 T 05-07-2017 IPR011009 Protein kinase-like domain K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 SMART SM00369 58 81 5.2 T 05-07-2017 IPR003591 Leucine-rich repeat, typical subtype K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 SMART SM00369 37 57 36.0 T 05-07-2017 IPR003591 Leucine-rich repeat, typical subtype K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 SMART SM00369 149 172 7.6 T 05-07-2017 IPR003591 Leucine-rich repeat, typical subtype K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 SMART SM00369 127 148 120.0 T 05-07-2017 IPR003591 Leucine-rich repeat, typical subtype K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 SMART SM00369 104 126 95.0 T 05-07-2017 IPR003591 Leucine-rich repeat, typical subtype K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 Pfam PF00069 Protein kinase domain 203 365 5.5E-17 T 05-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 Pfam PF13855 Leucine rich repeat 105 162 1.9E-8 T 05-07-2017 IPR001611 Leucine-rich repeat GO:0005515 K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 SUPERFAMILY SSF52058 9 196 1.94E-35 T 05-07-2017 IPR032675 Leucine-rich repeat domain, L domain-like K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 Gene3D G3DSA:1.10.510.10 324 367 1.2E-11 T 05-07-2017 K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 209 236 - T 05-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 Gene3D G3DSA:3.30.200.20 199 323 6.2E-12 T 05-07-2017 K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 SMART SM00364 126 145 94.0 T 05-07-2017 K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 SMART SM00364 58 77 41.0 T 05-07-2017 K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 SMART SM00364 103 122 40.0 T 05-07-2017 K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 SMART SM00364 35 54 16.0 T 05-07-2017 K08M4_RS06135 3d2c2955038b9b8226e6c70343fc745e 412 SMART SM00364 149 168 35.0 T 05-07-2017 K08M4_RS02430 53d5f38c18202ec5f74664ede3fab5d1 211 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 5 103 1.2E-34 T 05-07-2017 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 K08M4_RS02430 53d5f38c18202ec5f74664ede3fab5d1 211 PIRSF PIRSF016938 3 199 1.1E-32 T 05-07-2017 IPR026279 Sigma-E factor negative regulatory protein RseA GO:0006950|GO:0016989 K08M4_RS02430 53d5f38c18202ec5f74664ede3fab5d1 211 SUPERFAMILY SSF89069 8 71 4.05E-20 T 05-07-2017 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 K08M4_RS02430 53d5f38c18202ec5f74664ede3fab5d1 211 Pfam PF03873 Anti sigma-E protein RseA, C-terminal domain 142 194 1.1E-18 T 05-07-2017 IPR005573 Anti sigma-E protein RseA, C-terminal K08M4_RS12360 ba369e1ae9fa0f05322738f104932d15 242 Hamap MF_01872 tRNA1(Val) (adenine(37)-N6)-methyltransferase [yfiC]. 9 242 51.981 T 05-07-2017 IPR022882 tRNA1(Val) (adenine(37)-N6)-methyltransferase GO:0016430 KEGG: 00340+2.1.1.22 K08M4_RS12360 ba369e1ae9fa0f05322738f104932d15 242 Gene3D G3DSA:3.40.50.150 30 235 8.5E-39 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS12360 ba369e1ae9fa0f05322738f104932d15 242 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 114 120 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 K08M4_RS12360 ba369e1ae9fa0f05322738f104932d15 242 SUPERFAMILY SSF53335 8 170 5.63E-28 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS12360 ba369e1ae9fa0f05322738f104932d15 242 Pfam PF05175 Methyltransferase small domain 40 129 1.8E-15 T 05-07-2017 IPR007848 Methyltransferase small domain GO:0008168 K08M4_RS11545 6f4896db91fd6db2b269e0ca0b7ded63 143 SUPERFAMILY SSF82649 3 141 1.36E-49 T 05-07-2017 K08M4_RS11545 6f4896db91fd6db2b269e0ca0b7ded63 143 TIGRFAM TIGR03391 FeS_syn_CsdE: cysteine desulfurase, sulfur acceptor subunit CsdE 7 141 1.3E-46 T 05-07-2017 IPR017763 Cysteine desulfurase, sulphur acceptor subunit CsdE K08M4_RS11545 6f4896db91fd6db2b269e0ca0b7ded63 143 Gene3D G3DSA:3.90.1010.10 3 142 5.2E-54 T 05-07-2017 K08M4_RS11545 6f4896db91fd6db2b269e0ca0b7ded63 143 Pfam PF02657 Fe-S metabolism associated domain 20 139 1.1E-45 T 05-07-2017 IPR003808 Fe-S metabolism associated domain, SufE-like K08M4_RS16545 1c16b04e1058c287538bfc173a4d7c2c 198 Gene3D G3DSA:2.170.170.11 17 193 1.6E-48 T 05-07-2017 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 K08M4_RS16545 1c16b04e1058c287538bfc173a4d7c2c 198 SUPERFAMILY SSF51645 20 194 4.19E-21 T 05-07-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 K08M4_RS15870 9ae969e2015f9ac326db25f0229de03e 902 SUPERFAMILY SSF48452 442 805 3.04E-159 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS15870 9ae969e2015f9ac326db25f0229de03e 902 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 869 881 1.3E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS15870 9ae969e2015f9ac326db25f0229de03e 902 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 853 869 1.3E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS15870 9ae969e2015f9ac326db25f0229de03e 902 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 839 853 1.3E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS15870 9ae969e2015f9ac326db25f0229de03e 902 ProSitePatterns PS00622 LuxR-type HTH domain signature. 853 880 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS15870 9ae969e2015f9ac326db25f0229de03e 902 Hamap MF_01247 HTH-type transcriptional regulator MalT [malT]. 1 902 37.01 T 05-07-2017 IPR023768 Transcriptional regulator HTH-type, MalT K08M4_RS15870 9ae969e2015f9ac326db25f0229de03e 902 SUPERFAMILY SSF46894 830 894 1.33E-16 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS15870 9ae969e2015f9ac326db25f0229de03e 902 Gene3D G3DSA:1.25.40.10 445 810 1.1E-85 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS15870 9ae969e2015f9ac326db25f0229de03e 902 SUPERFAMILY SSF52540 14 227 7.3E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15870 9ae969e2015f9ac326db25f0229de03e 902 Gene3D G3DSA:3.40.50.300 30 164 7.2E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15870 9ae969e2015f9ac326db25f0229de03e 902 Gene3D G3DSA:1.10.10.10 835 894 3.6E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15870 9ae969e2015f9ac326db25f0229de03e 902 Pfam PF00196 Bacterial regulatory proteins, luxR family 838 892 2.2E-19 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS15870 9ae969e2015f9ac326db25f0229de03e 902 SMART SM00421 836 893 1.1E-19 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS12540 b0cc4d54192dc043aef3bb4fcc30a584 305 SUPERFAMILY SSF54211 3 125 5.76E-42 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS12540 b0cc4d54192dc043aef3bb4fcc30a584 305 Gene3D G3DSA:3.30.230.20 3 126 1.7E-46 T 05-07-2017 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 K08M4_RS12540 b0cc4d54192dc043aef3bb4fcc30a584 305 SUPERFAMILY SSF54211 134 278 1.06E-51 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS12540 b0cc4d54192dc043aef3bb4fcc30a584 305 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 276 2.2E-107 T 05-07-2017 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 K08M4_RS12540 b0cc4d54192dc043aef3bb4fcc30a584 305 Gene3D G3DSA:3.30.1700.10 129 283 6.9E-61 T 05-07-2017 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 K08M4_RS12540 b0cc4d54192dc043aef3bb4fcc30a584 305 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 280 46.052 T 05-07-2017 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 K08M4_RS12540 b0cc4d54192dc043aef3bb4fcc30a584 305 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 298 1.2E-141 T 05-07-2017 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 Pfam PF00183 Hsp90 protein 226 633 1.1E-127 T 05-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 SMART SM00387 32 189 7.6E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 SUPERFAMILY SSF54211 238 493 4.25E-99 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 SUPERFAMILY SSF55874 10 216 4.45E-63 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 187 1.9E-13 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 Gene3D G3DSA:3.30.565.10 10 246 4.0E-80 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 Hamap MF_00505 Chaperone protein HtpG [htpG]. 7 632 31.8 T 05-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 PIRSF PIRSF002583 1 634 3.0E-212 T 05-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 PRINTS PR00775 90kDa heat shock protein signature 31 53 2.0E-61 T 05-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 PRINTS PR00775 90kDa heat shock protein signature 10 30 2.0E-61 T 05-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 PRINTS PR00775 90kDa heat shock protein signature 125 147 2.0E-61 T 05-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 PRINTS PR00775 90kDa heat shock protein signature 177 194 2.0E-61 T 05-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 PRINTS PR00775 90kDa heat shock protein signature 98 115 2.0E-61 T 05-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 PRINTS PR00775 90kDa heat shock protein signature 80 97 2.0E-61 T 05-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 PRINTS PR00775 90kDa heat shock protein signature 195 213 2.0E-61 T 05-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 30 39 - T 05-07-2017 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 K08M4_RS10695 db7cf49dee75151a0a05d03d0cd5902e 634 SUPERFAMILY SSF110942 520 632 4.58E-32 T 05-07-2017 K08M4_RS14510 a96167a87621d2cb44802e4bcb1751c0 345 SUPERFAMILY SSF51905 1 191 1.82E-44 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14510 a96167a87621d2cb44802e4bcb1751c0 345 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 7 339 1.9E-97 T 05-07-2017 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like K08M4_RS14510 a96167a87621d2cb44802e4bcb1751c0 345 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 167 6.2E-7 T 05-07-2017 K08M4_RS14510 a96167a87621d2cb44802e4bcb1751c0 345 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 6.2E-7 T 05-07-2017 K08M4_RS14510 a96167a87621d2cb44802e4bcb1751c0 345 Gene3D G3DSA:2.40.30.10 198 272 5.6E-28 T 05-07-2017 K08M4_RS14510 a96167a87621d2cb44802e4bcb1751c0 345 Gene3D G3DSA:3.50.50.60 2 197 7.8E-42 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14510 a96167a87621d2cb44802e4bcb1751c0 345 Gene3D G3DSA:1.10.8.260 273 325 2.6E-23 T 05-07-2017 IPR023166 HI0933 insert-like domain K08M4_RS14510 a96167a87621d2cb44802e4bcb1751c0 345 SUPERFAMILY SSF160996 193 339 9.29E-41 T 05-07-2017 K08M4_RS14510 a96167a87621d2cb44802e4bcb1751c0 345 Pfam PF03486 HI0933-like protein 5 340 3.1E-122 T 05-07-2017 K08M4_RS03985 0dc4d3fc470393de98d9ac9cf9e0deda 357 SUPERFAMILY SSF53335 99 342 9.15E-37 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS03985 0dc4d3fc470393de98d9ac9cf9e0deda 357 SUPERFAMILY SSF46785 19 99 1.59E-7 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS03985 0dc4d3fc470393de98d9ac9cf9e0deda 357 Pfam PF00891 O-methyltransferase 172 337 9.5E-13 T 05-07-2017 IPR001077 O-methyltransferase, family 2 GO:0008171 K08M4_RS03985 0dc4d3fc470393de98d9ac9cf9e0deda 357 Gene3D G3DSA:3.40.50.150 99 344 6.1E-36 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS03985 0dc4d3fc470393de98d9ac9cf9e0deda 357 PIRSF PIRSF005739 5 345 3.4E-8 T 05-07-2017 IPR016461 O-methyltransferase COMT-type GO:0008168 K08M4_RS00025 803deb65b356325a21e93c247e4ec8ea 144 SUPERFAMILY SSF49764 6 138 4.19E-23 T 05-07-2017 IPR008978 HSP20-like chaperone K08M4_RS00025 803deb65b356325a21e93c247e4ec8ea 144 Pfam PF00011 Hsp20/alpha crystallin family 43 137 1.2E-19 T 05-07-2017 IPR002068 Alpha crystallin/Hsp20 domain K08M4_RS00025 803deb65b356325a21e93c247e4ec8ea 144 Gene3D G3DSA:2.60.40.790 4 137 5.7E-19 T 05-07-2017 IPR008978 HSP20-like chaperone K08M4_RS12355 32785dc9a38566be0af8987dac2da825 437 Pfam PF05525 Branched-chain amino acid transport protein 8 426 1.5E-152 T 05-07-2017 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 K08M4_RS12355 32785dc9a38566be0af8987dac2da825 437 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 413 1.3E-136 T 05-07-2017 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 K08M4_RS01315 b62c04674360ed887893d7496ff5c698 864 Gene3D G3DSA:3.60.10.10 471 841 5.9E-20 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS01315 b62c04674360ed887893d7496ff5c698 864 SUPERFAMILY SSF56219 746 841 8.64E-28 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS01315 b62c04674360ed887893d7496ff5c698 864 SUPERFAMILY SSF56219 682 712 8.64E-28 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS01315 b62c04674360ed887893d7496ff5c698 864 SUPERFAMILY SSF56219 471 655 8.64E-28 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS01315 b62c04674360ed887893d7496ff5c698 864 Pfam PF00932 Lamin Tail Domain 20 130 1.8E-15 T 05-07-2017 IPR001322 Lamin Tail Domain K08M4_RS01315 b62c04674360ed887893d7496ff5c698 864 SUPERFAMILY SSF74853 19 129 5.89E-7 T 05-07-2017 IPR001322 Lamin Tail Domain K08M4_RS06315 98b605fa0a740f7463d3cbc52c3ab2bf 157 Gene3D G3DSA:3.40.50.2300 5 131 4.8E-22 T 05-07-2017 K08M4_RS06315 98b605fa0a740f7463d3cbc52c3ab2bf 157 SMART SM00448 4 125 7.5E-11 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS06315 98b605fa0a740f7463d3cbc52c3ab2bf 157 SUPERFAMILY SSF52172 2 130 1.31E-20 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS06315 98b605fa0a740f7463d3cbc52c3ab2bf 157 Pfam PF00072 Response regulator receiver domain 7 125 2.2E-14 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS09065 0608491d313d0d8abb0d9696807e61a8 228 SUPERFAMILY SSF54862 42 224 1.36E-63 T 05-07-2017 K08M4_RS09065 0608491d313d0d8abb0d9696807e61a8 228 Gene3D G3DSA:3.30.70.20 43 102 2.0E-34 T 05-07-2017 K08M4_RS09065 0608491d313d0d8abb0d9696807e61a8 228 Gene3D G3DSA:3.30.70.20 173 226 2.0E-34 T 05-07-2017 K08M4_RS09065 0608491d313d0d8abb0d9696807e61a8 228 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 132 143 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS09065 0608491d313d0d8abb0d9696807e61a8 228 Gene3D G3DSA:3.30.70.20 136 172 1.2E-16 T 05-07-2017 K08M4_RS09065 0608491d313d0d8abb0d9696807e61a8 228 Pfam PF13247 4Fe-4S dicluster domain 91 188 1.2E-25 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain K08M4_RS09065 0608491d313d0d8abb0d9696807e61a8 228 TIGRFAM TIGR03149 cyt_nit_nrfC: cytochrome c nitrite reductase, Fe-S protein 2 228 2.8E-129 T 05-07-2017 IPR017567 Cytochrome c nitrite reductase, Fe-S protein K08M4_RS09065 0608491d313d0d8abb0d9696807e61a8 228 Gene3D G3DSA:3.30.70.20 103 135 3.5E-13 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 SUPERFAMILY SSF51905 4 319 2.75E-58 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 4.5E-29 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 139 157 4.5E-29 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 4.5E-29 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 278 4.5E-29 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 291 313 4.5E-29 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 PIRSF PIRSF000350 2 463 1.5E-72 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 Hamap MF_00247 Soluble pyridine nucleotide transhydrogenase [sthA]. 2 466 64.934 T 05-07-2017 IPR022962 Soluble pyridine nucleotide transhydrogenase GO:0003957|GO:0055114 KEGG: 00760+1.6.1.1|MetaCyc: PWY-5083 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 SUPERFAMILY SSF55424 345 463 1.89E-30 T 05-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.5E-52 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 263 277 1.5E-52 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 1.5E-52 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 1.5E-52 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 313 1.5E-52 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 1.5E-52 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 1.5E-52 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 151 1.5E-52 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 1.5E-52 T 05-07-2017 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 326 1.5E-60 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 Gene3D G3DSA:3.30.390.30 345 460 3.9E-33 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 Gene3D G3DSA:3.50.50.60 153 268 4.4E-25 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 457 3.1E-30 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 Gene3D G3DSA:3.50.50.60 270 339 8.4E-57 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS00625 a90d8a193c80412a11eb85640f037d11 466 Gene3D G3DSA:3.50.50.60 6 150 8.4E-57 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14450 201e398591dcc3dd85d91a5d159419ed 543 Gene3D G3DSA:3.40.50.150 203 442 2.1E-37 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS14450 201e398591dcc3dd85d91a5d159419ed 543 SUPERFAMILY SSF53335 9 49 7.77E-95 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS14450 201e398591dcc3dd85d91a5d159419ed 543 SUPERFAMILY SSF53335 88 540 7.77E-95 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS14450 201e398591dcc3dd85d91a5d159419ed 543 Pfam PF02384 N-6 DNA Methylase 178 497 2.2E-63 T 05-07-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 K08M4_RS14450 201e398591dcc3dd85d91a5d159419ed 543 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 308 314 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 K08M4_RS14450 201e398591dcc3dd85d91a5d159419ed 543 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 201 217 3.0E-19 T 05-07-2017 K08M4_RS14450 201e398591dcc3dd85d91a5d159419ed 543 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 305 317 3.0E-19 T 05-07-2017 K08M4_RS14450 201e398591dcc3dd85d91a5d159419ed 543 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 231 245 3.0E-19 T 05-07-2017 K08M4_RS14450 201e398591dcc3dd85d91a5d159419ed 543 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 350 374 3.0E-19 T 05-07-2017 K08M4_RS10120 08ec1dbdc0409bd56063888219b79195 146 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 7 145 1.5E-56 T 05-07-2017 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 K08M4_RS10120 08ec1dbdc0409bd56063888219b79195 146 ProSitePatterns PS00552 MerR-type HTH domain signature. 10 32 - T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 K08M4_RS10120 08ec1dbdc0409bd56063888219b79195 146 SUPERFAMILY SSF46955 6 117 3.66E-27 T 05-07-2017 IPR009061 Putative DNA-binding domain K08M4_RS10120 08ec1dbdc0409bd56063888219b79195 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 3.1E-11 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 K08M4_RS10120 08ec1dbdc0409bd56063888219b79195 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 3.1E-11 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 K08M4_RS10120 08ec1dbdc0409bd56063888219b79195 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 3.1E-11 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 K08M4_RS10120 08ec1dbdc0409bd56063888219b79195 146 Gene3D G3DSA:1.10.1660.10 6 60 2.7E-21 T 05-07-2017 K08M4_RS10120 08ec1dbdc0409bd56063888219b79195 146 Pfam PF13411 MerR HTH family regulatory protein 8 73 4.1E-16 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 K08M4_RS10120 08ec1dbdc0409bd56063888219b79195 146 SMART SM00422 7 75 4.6E-22 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 K08M4_RS10120 08ec1dbdc0409bd56063888219b79195 146 Gene3D G3DSA:1.10.1660.10 61 139 1.9E-14 T 05-07-2017 K08M4_RS00800 c11bd2bbcbe36cdaa58a99a39111564b 125 Hamap MF_00422 Protein translocase subunit SecE [secE]. 66 121 13.873 T 05-07-2017 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 K08M4_RS00800 c11bd2bbcbe36cdaa58a99a39111564b 125 Gene3D G3DSA:1.20.5.1030 64 121 9.1E-25 T 05-07-2017 K08M4_RS00800 c11bd2bbcbe36cdaa58a99a39111564b 125 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 71 99 - T 05-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 K08M4_RS00800 c11bd2bbcbe36cdaa58a99a39111564b 125 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 70 121 9.8E-21 T 05-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 K08M4_RS00800 c11bd2bbcbe36cdaa58a99a39111564b 125 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 70 122 3.0E-19 T 05-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 K08M4_RS00800 c11bd2bbcbe36cdaa58a99a39111564b 125 PRINTS PR01650 Bacterial translocase SecE signature 65 85 1.4E-40 T 05-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 K08M4_RS00800 c11bd2bbcbe36cdaa58a99a39111564b 125 PRINTS PR01650 Bacterial translocase SecE signature 44 65 1.4E-40 T 05-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 K08M4_RS00800 c11bd2bbcbe36cdaa58a99a39111564b 125 PRINTS PR01650 Bacterial translocase SecE signature 89 109 1.4E-40 T 05-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 K08M4_RS00800 c11bd2bbcbe36cdaa58a99a39111564b 125 PRINTS PR01650 Bacterial translocase SecE signature 109 125 1.4E-40 T 05-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 K08M4_RS13650 013c4eb4ef8fcb7fd1e52551b2f86c6f 471 Pfam PF00939 Sodium:sulfate symporter transmembrane region 9 466 3.3E-47 T 05-07-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 K08M4_RS13650 013c4eb4ef8fcb7fd1e52551b2f86c6f 471 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 36 466 6.3E-80 T 05-07-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 K08M4_RS11600 a3f2db053e8cabb85549dee021c29995 298 Gene3D G3DSA:1.10.10.10 3 78 1.4E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS11600 a3f2db053e8cabb85549dee021c29995 298 Gene3D G3DSA:3.40.190.10 92 177 1.1E-11 T 05-07-2017 K08M4_RS11600 a3f2db053e8cabb85549dee021c29995 298 Gene3D G3DSA:3.40.190.10 178 261 3.7E-18 T 05-07-2017 K08M4_RS11600 a3f2db053e8cabb85549dee021c29995 298 Pfam PF03466 LysR substrate binding domain 89 293 2.0E-42 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS11600 a3f2db053e8cabb85549dee021c29995 298 SUPERFAMILY SSF46785 3 78 1.36E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS11600 a3f2db053e8cabb85549dee021c29995 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 2.7E-15 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS11600 a3f2db053e8cabb85549dee021c29995 298 SUPERFAMILY SSF53850 89 295 1.08E-35 T 05-07-2017 K08M4_RS06180 27c779b3ac772209c0935cc439709d73 208 SUPERFAMILY SSF51569 3 207 1.7E-65 T 05-07-2017 K08M4_RS06180 27c779b3ac772209c0935cc439709d73 208 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 6 205 2.1E-81 T 05-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 K08M4_RS06180 27c779b3ac772209c0935cc439709d73 208 Gene3D G3DSA:3.20.20.70 2 207 4.5E-74 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS06180 27c779b3ac772209c0935cc439709d73 208 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 124 137 - T 05-07-2017 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 K08M4_RS06180 27c779b3ac772209c0935cc439709d73 208 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 36 45 - T 05-07-2017 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 K08M4_RS06180 27c779b3ac772209c0935cc439709d73 208 Pfam PF01081 KDPG and KHG aldolase 5 197 5.5E-70 T 05-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 K08M4_RS20990 1a04af513f2faf460546da8146f098c9 639 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 282 623 1.3E-83 T 05-07-2017 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 K08M4_RS20990 1a04af513f2faf460546da8146f098c9 639 SUPERFAMILY SSF52794 169 264 2.96E-34 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS20990 1a04af513f2faf460546da8146f098c9 639 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 146 6.8E-36 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS20990 1a04af513f2faf460546da8146f098c9 639 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 172 261 3.9E-15 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS20990 1a04af513f2faf460546da8146f098c9 639 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 5 131 3.6E-41 T 05-07-2017 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 K08M4_RS20990 1a04af513f2faf460546da8146f098c9 639 Gene3D G3DSA:3.40.930.10 1 146 1.7E-47 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS20990 1a04af513f2faf460546da8146f098c9 639 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 170 253 2.6E-29 T 05-07-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 K08M4_RS20990 1a04af513f2faf460546da8146f098c9 639 Gene3D G3DSA:3.40.50.2300 165 265 2.7E-39 T 05-07-2017 K08M4_RS20990 1a04af513f2faf460546da8146f098c9 639 SUPERFAMILY SSF55804 1 145 1.31E-39 T 05-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 K08M4_RS20990 1a04af513f2faf460546da8146f098c9 639 Pfam PF02378 Phosphotransferase system, EIIC 296 571 7.4E-15 T 05-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 K08M4_RS20840 a302be14f863f0285e191110cf711fd5 274 Gene3D G3DSA:1.10.3720.10 79 272 1.3E-25 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS20840 a302be14f863f0285e191110cf711fd5 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 273 4.8E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS20840 a302be14f863f0285e191110cf711fd5 274 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 32 273 1.7E-79 T 05-07-2017 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 K08M4_RS20840 a302be14f863f0285e191110cf711fd5 274 SUPERFAMILY SSF161098 80 265 1.09E-31 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS19255 82f92af41c4d27cf192d23fabb9f1d0a 327 PIRSF PIRSF002849 1 327 5.4E-127 T 05-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted K08M4_RS19255 82f92af41c4d27cf192d23fabb9f1d0a 327 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 38 170 6.8E-61 T 05-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 K08M4_RS19255 82f92af41c4d27cf192d23fabb9f1d0a 327 Gene3D G3DSA:3.40.50.300 19 186 1.4E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19255 82f92af41c4d27cf192d23fabb9f1d0a 327 SUPERFAMILY SSF52540 5 301 1.17E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19255 82f92af41c4d27cf192d23fabb9f1d0a 327 Gene3D G3DSA:1.10.8.300 208 324 1.7E-38 T 05-07-2017 K08M4_RS17470 18db15d3d12c95b0180939362c5f2e99 483 SUPERFAMILY SSF49899 29 191 1.8E-15 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain K08M4_RS17470 18db15d3d12c95b0180939362c5f2e99 483 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 379 478 7.7E-22 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS17470 18db15d3d12c95b0180939362c5f2e99 483 Gene3D G3DSA:2.60.120.200 41 209 9.4E-16 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 Gene3D G3DSA:2.10.10.20 33 86 1.5E-15 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 SMART SM00495 1011 1053 1.8E-9 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 SMART SM00495 37 83 1.3E-12 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 Pfam PF02839 Carbohydrate binding domain 38 74 1.7E-10 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 SMART SM00636 322 782 1.1E-120 T 05-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 Pfam PF00704 Glycosyl hydrolases family 18 323 782 2.5E-80 T 05-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 SUPERFAMILY SSF51055 998 1054 6.15E-14 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 Gene3D G3DSA:3.10.50.10 729 748 1.2E-20 T 05-07-2017 IPR029070 Chitinase insertion domain K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 Gene3D G3DSA:3.10.50.10 636 686 1.2E-20 T 05-07-2017 IPR029070 Chitinase insertion domain K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 SUPERFAMILY SSF51445 754 786 7.06E-75 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 SUPERFAMILY SSF51445 316 629 7.06E-75 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 Pfam PF14600 Cellulose-binding domain 1000 1053 8.0E-17 T 05-07-2017 IPR032798 Endoglucanase Z, cellulose-binding domain KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 Gene3D G3DSA:2.10.10.20 998 1054 5.7E-20 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 SUPERFAMILY SSF54556 629 752 2.29E-14 T 05-07-2017 IPR029070 Chitinase insertion domain K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 ProSitePatterns PS01095 Chitinases family 18 active site. 471 479 - T 05-07-2017 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 SUPERFAMILY SSF51055 22 86 9.68E-15 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 Pfam PF06483 Chitinase C 810 975 1.9E-71 T 05-07-2017 IPR009470 Chitinase, C-terminal KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 Gene3D G3DSA:3.20.20.80 612 635 4.5E-91 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 Gene3D G3DSA:3.20.20.80 749 790 4.5E-91 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 Gene3D G3DSA:3.20.20.80 320 578 4.5E-91 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS17640 053090e86fb65995fbe8de7806442281 1055 Gene3D G3DSA:3.20.20.80 697 698 4.5E-91 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS18230 2ec1ae42ca5f2c145b54caa527b7ae82 255 Pfam PF11932 Protein of unknown function (DUF3450) 8 248 7.4E-87 T 05-07-2017 IPR016866 Uncharacterised conserved protein UCP028069 K08M4_RS18230 2ec1ae42ca5f2c145b54caa527b7ae82 255 PIRSF PIRSF028069 1 255 1.9E-100 T 05-07-2017 IPR016866 Uncharacterised conserved protein UCP028069 K08M4_RS18075 2ec1ae42ca5f2c145b54caa527b7ae82 255 Pfam PF11932 Protein of unknown function (DUF3450) 8 248 7.4E-87 T 05-07-2017 IPR016866 Uncharacterised conserved protein UCP028069 K08M4_RS18075 2ec1ae42ca5f2c145b54caa527b7ae82 255 PIRSF PIRSF028069 1 255 1.9E-100 T 05-07-2017 IPR016866 Uncharacterised conserved protein UCP028069 K08M4_RS07905 21b9e667e465de4efc78783f6968d3e9 401 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 396 1.1E-10 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07905 21b9e667e465de4efc78783f6968d3e9 401 SUPERFAMILY SSF161098 193 382 5.89E-24 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07905 21b9e667e465de4efc78783f6968d3e9 401 SUPERFAMILY SSF161098 91 161 2.29E-11 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07905 21b9e667e465de4efc78783f6968d3e9 401 Gene3D G3DSA:1.10.3720.10 90 160 7.3E-13 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07905 21b9e667e465de4efc78783f6968d3e9 401 Gene3D G3DSA:1.10.3720.10 193 396 6.7E-35 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07905 21b9e667e465de4efc78783f6968d3e9 401 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 92 155 1.3E-16 T 05-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 K08M4_RS08405 5088cee48eb5b3a72d107ae3d7423939 176 SUPERFAMILY SSF53098 4 175 1.69E-27 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS08405 5088cee48eb5b3a72d107ae3d7423939 176 Gene3D G3DSA:3.30.420.10 3 176 8.0E-36 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS08405 5088cee48eb5b3a72d107ae3d7423939 176 Pfam PF00929 Exonuclease 7 171 7.3E-10 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS08405 5088cee48eb5b3a72d107ae3d7423939 176 SMART SM00479 5 176 4.9E-4 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS15170 b466fc43980ad07a9ff2fbcfc19c9ccd 704 SMART SM00382 495 681 6.8E-18 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS15170 b466fc43980ad07a9ff2fbcfc19c9ccd 704 Gene3D G3DSA:3.40.50.300 468 694 2.2E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15170 b466fc43980ad07a9ff2fbcfc19c9ccd 704 SUPERFAMILY SSF90123 136 452 2.22E-48 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS15170 b466fc43980ad07a9ff2fbcfc19c9ccd 704 TIGRFAM TIGR03375 type_I_sec_LssB: type I secretion system ATPase 3 698 1.5E-292 T 05-07-2017 IPR017750 ATPase, type I secretion system K08M4_RS15170 b466fc43980ad07a9ff2fbcfc19c9ccd 704 Gene3D G3DSA:3.90.70.10 2 126 1.1E-40 T 05-07-2017 K08M4_RS15170 b466fc43980ad07a9ff2fbcfc19c9ccd 704 SUPERFAMILY SSF52540 459 693 2.07E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15170 b466fc43980ad07a9ff2fbcfc19c9ccd 704 Gene3D G3DSA:1.20.1560.10 142 452 4.2E-49 T 05-07-2017 K08M4_RS15170 b466fc43980ad07a9ff2fbcfc19c9ccd 704 Pfam PF00664 ABC transporter transmembrane region 158 417 1.3E-18 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS15170 b466fc43980ad07a9ff2fbcfc19c9ccd 704 Pfam PF00005 ABC transporter 487 635 5.1E-34 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS15230 c8cf825329c0c7be83153d03f2ed0ba0 218 Pfam PF13599 Pentapeptide repeats (9 copies) 19 99 6.9E-12 T 05-07-2017 IPR001646 Pentapeptide repeat K08M4_RS15230 c8cf825329c0c7be83153d03f2ed0ba0 218 Pfam PF00805 Pentapeptide repeats (8 copies) 122 161 7.3E-7 T 05-07-2017 IPR001646 Pentapeptide repeat K08M4_RS15230 c8cf825329c0c7be83153d03f2ed0ba0 218 SUPERFAMILY SSF141571 4 48 3.14E-8 T 05-07-2017 K08M4_RS15230 c8cf825329c0c7be83153d03f2ed0ba0 218 SUPERFAMILY SSF141571 53 216 9.68E-38 T 05-07-2017 K08M4_RS04080 9ce7213dfbfebb655f71d87b0340b397 313 PRINTS PR01002 Flagellar protein FlgJ signature 227 248 3.1E-26 T 05-07-2017 K08M4_RS04080 9ce7213dfbfebb655f71d87b0340b397 313 PRINTS PR01002 Flagellar protein FlgJ signature 79 101 3.1E-26 T 05-07-2017 K08M4_RS04080 9ce7213dfbfebb655f71d87b0340b397 313 PRINTS PR01002 Flagellar protein FlgJ signature 31 54 3.1E-26 T 05-07-2017 K08M4_RS04080 9ce7213dfbfebb655f71d87b0340b397 313 PRINTS PR01002 Flagellar protein FlgJ signature 249 270 3.1E-26 T 05-07-2017 K08M4_RS04080 9ce7213dfbfebb655f71d87b0340b397 313 PRINTS PR01002 Flagellar protein FlgJ signature 186 204 3.1E-26 T 05-07-2017 K08M4_RS04080 9ce7213dfbfebb655f71d87b0340b397 313 PRINTS PR01002 Flagellar protein FlgJ signature 292 310 3.1E-26 T 05-07-2017 K08M4_RS04080 9ce7213dfbfebb655f71d87b0340b397 313 SMART SM00047 152 313 5.2E-50 T 05-07-2017 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 K08M4_RS04080 9ce7213dfbfebb655f71d87b0340b397 313 Pfam PF10135 Rod binding protein 53 102 7.3E-14 T 05-07-2017 IPR019301 Flagellar protein FlgJ, N-terminal K08M4_RS04080 9ce7213dfbfebb655f71d87b0340b397 313 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 10 309 1.3E-102 T 05-07-2017 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 K08M4_RS04080 9ce7213dfbfebb655f71d87b0340b397 313 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 173 309 2.6E-20 T 05-07-2017 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 K08M4_RS08655 84d3e1805e1668b291cc08c492e098fb 439 SUPERFAMILY SSF56796 1 380 1.44E-88 T 05-07-2017 K08M4_RS08655 84d3e1805e1668b291cc08c492e098fb 439 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 372 2.4E-90 T 05-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 K08M4_RS08655 84d3e1805e1668b291cc08c492e098fb 439 Gene3D G3DSA:3.40.50.1970 1 179 3.1E-48 T 05-07-2017 K08M4_RS08655 84d3e1805e1668b291cc08c492e098fb 439 Gene3D G3DSA:1.20.1090.10 188 381 7.4E-42 T 05-07-2017 K08M4_RS16865 4b2bbd1baced2d98dbaa068aaa0f79cc 380 Pfam PF01625 Peptide methionine sulfoxide reductase 43 193 6.1E-56 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS16865 4b2bbd1baced2d98dbaa068aaa0f79cc 380 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 40 199 34.893 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS16865 4b2bbd1baced2d98dbaa068aaa0f79cc 380 Gene3D G3DSA:2.170.150.20 233 378 3.2E-58 T 05-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS16865 4b2bbd1baced2d98dbaa068aaa0f79cc 380 SUPERFAMILY SSF51316 237 379 2.25E-58 T 05-07-2017 IPR011057 Mss4-like K08M4_RS16865 4b2bbd1baced2d98dbaa068aaa0f79cc 380 Pfam PF01641 SelR domain 243 362 1.1E-45 T 05-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS16865 4b2bbd1baced2d98dbaa068aaa0f79cc 380 SUPERFAMILY SSF55068 22 205 3.14E-69 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS16865 4b2bbd1baced2d98dbaa068aaa0f79cc 380 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 238 371 3.8E-59 T 05-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS16865 4b2bbd1baced2d98dbaa068aaa0f79cc 380 Gene3D G3DSA:3.30.1060.10 28 192 1.9E-64 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS16865 4b2bbd1baced2d98dbaa068aaa0f79cc 380 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 41 192 3.5E-49 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS05480 effbccf8559f65befaaf0fcf9de4c34a 630 Gene3D G3DSA:1.10.287.950 383 598 3.9E-56 T 05-07-2017 K08M4_RS05480 effbccf8559f65befaaf0fcf9de4c34a 630 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 495 524 8.0E-22 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS05480 effbccf8559f65befaaf0fcf9de4c34a 630 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 389 418 8.0E-22 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS05480 effbccf8559f65befaaf0fcf9de4c34a 630 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 466 493 8.0E-22 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS05480 effbccf8559f65befaaf0fcf9de4c34a 630 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 416 628 8.1E-45 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS05480 effbccf8559f65befaaf0fcf9de4c34a 630 SUPERFAMILY SSF58104 343 630 4.19E-72 T 05-07-2017 K08M4_RS05480 effbccf8559f65befaaf0fcf9de4c34a 630 SMART SM00283 368 629 2.9E-69 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS05480 effbccf8559f65befaaf0fcf9de4c34a 630 Pfam PF02743 Cache domain 53 258 7.8E-18 T 05-07-2017 IPR033479 Double Cache domain 1 K08M4_RS05480 effbccf8559f65befaaf0fcf9de4c34a 630 Gene3D G3DSA:3.30.450.20 143 274 1.2E-12 T 05-07-2017 K08M4_RS02825 ee56c97a9dfe825828282f2953f3e3c2 892 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 4 891 0.0 T 05-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 K08M4_RS02825 ee56c97a9dfe825828282f2953f3e3c2 892 PIRSF PIRSF000156 1 892 0.0 T 05-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 K08M4_RS02825 ee56c97a9dfe825828282f2953f3e3c2 892 Gene3D G3DSA:3.40.50.920 707 890 1.6E-73 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 K08M4_RS02825 ee56c97a9dfe825828282f2953f3e3c2 892 Gene3D G3DSA:3.40.50.970 56 469 1.8E-152 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS02825 ee56c97a9dfe825828282f2953f3e3c2 892 SUPERFAMILY SSF52518 56 469 1.9E-140 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS02825 ee56c97a9dfe825828282f2953f3e3c2 892 Gene3D G3DSA:3.40.50.970 473 705 2.4E-121 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS02825 ee56c97a9dfe825828282f2953f3e3c2 892 SUPERFAMILY SSF52922 702 891 2.97E-57 T 05-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 K08M4_RS02825 ee56c97a9dfe825828282f2953f3e3c2 892 SUPERFAMILY SSF52518 474 701 2.12E-97 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS02825 ee56c97a9dfe825828282f2953f3e3c2 892 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 103 298 2.4E-10 T 05-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS02825 ee56c97a9dfe825828282f2953f3e3c2 892 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 360 426 9.8E-6 T 05-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 K08M4_RS19820 9477c654f9d8d756885facab13aee9ff 365 SUPERFAMILY SSF48452 64 160 1.31E-9 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS19820 9477c654f9d8d756885facab13aee9ff 365 Pfam PF02698 DUF218 domain 194 311 2.0E-18 T 05-07-2017 IPR003848 Domain of unknown function DUF218 K08M4_RS19820 9477c654f9d8d756885facab13aee9ff 365 Gene3D G3DSA:3.40.50.620 193 309 5.2E-17 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS19820 9477c654f9d8d756885facab13aee9ff 365 Gene3D G3DSA:1.25.40.10 85 159 1.2E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS03475 aecce633ff64fd78297325ecf09f3a32 129 Pfam PF07417 Transcriptional regulator Crl 6 123 2.7E-48 T 05-07-2017 IPR009986 Sigma factor-binding protein Crl GO:0005737|GO:0045893 K08M4_RS03475 aecce633ff64fd78297325ecf09f3a32 129 Hamap MF_01178 Sigma factor-binding protein Crl [crl]. 2 129 31.424 T 05-07-2017 IPR009986 Sigma factor-binding protein Crl GO:0005737|GO:0045893 K08M4_RS13025 e87f0ca7074dc0d03154bfb55c638df7 311 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 1 145 4.8E-47 T 05-07-2017 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 K08M4_RS13025 e87f0ca7074dc0d03154bfb55c638df7 311 SUPERFAMILY SSF51735 1 145 1.13E-39 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13025 e87f0ca7074dc0d03154bfb55c638df7 311 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 146 158 - T 05-07-2017 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 K08M4_RS13025 e87f0ca7074dc0d03154bfb55c638df7 311 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 147 309 1.3E-49 T 05-07-2017 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 K08M4_RS13025 e87f0ca7074dc0d03154bfb55c638df7 311 Gene3D G3DSA:3.40.50.720 1 145 5.9E-59 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13025 e87f0ca7074dc0d03154bfb55c638df7 311 PIRSF PIRSF000102 1 309 2.3E-62 T 05-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 K08M4_RS13025 e87f0ca7074dc0d03154bfb55c638df7 311 Gene3D G3DSA:3.90.110.10 147 311 8.6E-64 T 05-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 K08M4_RS13025 e87f0ca7074dc0d03154bfb55c638df7 311 Hamap MF_01516 Malate dehydrogenase [mdh]. 1 311 57.029 T 05-07-2017 IPR023958 Malate dehydrogenase, type 1, bacterial GO:0006099|GO:0030060|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 K08M4_RS13025 e87f0ca7074dc0d03154bfb55c638df7 311 TIGRFAM TIGR01772 MDH_euk_gproteo: malate dehydrogenase, NAD-dependent 2 310 6.4E-128 T 05-07-2017 IPR010097 Malate dehydrogenase, type 1 GO:0006108|GO:0030060|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263|Reactome: R-HSA-71403 K08M4_RS13025 e87f0ca7074dc0d03154bfb55c638df7 311 SUPERFAMILY SSF56327 147 309 3.86E-43 T 05-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 K08M4_RS08550 e4d013209aaf022b2048df873f47b841 492 Pfam PF13487 HD domain 361 430 9.1E-18 T 05-07-2017 K08M4_RS08550 e4d013209aaf022b2048df873f47b841 492 Gene3D G3DSA:1.10.3210.10 297 481 3.7E-20 T 05-07-2017 IPR006674 HD domain K08M4_RS08550 e4d013209aaf022b2048df873f47b841 492 SUPERFAMILY SSF109604 278 476 3.14E-33 T 05-07-2017 K08M4_RS08550 e4d013209aaf022b2048df873f47b841 492 SMART SM00471 298 448 6.9E-9 T 05-07-2017 IPR003607 HD/PDEase domain K08M4_RS13170 8ed5210d3ced309beaf6157534dd4b09 279 SUPERFAMILY SSF52540 5 260 6.88E-28 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13170 8ed5210d3ced309beaf6157534dd4b09 279 Pfam PF13401 AAA domain 42 168 6.3E-25 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS13170 8ed5210d3ced309beaf6157534dd4b09 279 Gene3D G3DSA:3.40.50.300 29 180 2.3E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02170 be52be1ac59b36a4c2ac33d89e341581 140 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 3 139 24.2 T 05-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 K08M4_RS02170 be52be1ac59b36a4c2ac33d89e341581 140 SUPERFAMILY SSF53098 3 137 8.5E-37 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS02170 be52be1ac59b36a4c2ac33d89e341581 140 SMART SM00732 3 104 1.6E-34 T 05-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 K08M4_RS02170 be52be1ac59b36a4c2ac33d89e341581 140 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 6 136 2.2E-48 T 05-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 K08M4_RS02170 be52be1ac59b36a4c2ac33d89e341581 140 Gene3D G3DSA:3.30.420.140 3 138 3.5E-41 T 05-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 K08M4_RS02170 be52be1ac59b36a4c2ac33d89e341581 140 Pfam PF03652 Holliday junction resolvase 4 136 5.6E-36 T 05-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 K08M4_RS17905 68aecb3c70ff6a0993fb8fc8638104f4 228 SUPERFAMILY SSF49354 17 125 1.65E-8 T 05-07-2017 IPR008962 PapD-like K08M4_RS17905 68aecb3c70ff6a0993fb8fc8638104f4 228 Gene3D G3DSA:2.60.40.360 21 139 1.2E-4 T 05-07-2017 IPR008962 PapD-like K08M4_RS11375 486ac498a1bf3c5130db385e853bbca6 183 Gene3D G3DSA:3.40.50.1000 3 181 3.6E-58 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS11375 486ac498a1bf3c5130db385e853bbca6 183 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 4 153 1.9E-37 T 05-07-2017 IPR006543 Histidinol-phosphate phosphatase GO:0016791 K08M4_RS11375 486ac498a1bf3c5130db385e853bbca6 183 PIRSF PIRSF004682 1 183 1.6E-63 T 05-07-2017 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 K08M4_RS11375 486ac498a1bf3c5130db385e853bbca6 183 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 5 154 1.8E-34 T 05-07-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 K08M4_RS11375 486ac498a1bf3c5130db385e853bbca6 183 TIGRFAM TIGR00213 GmhB_yaeD: D,D-heptose 1,7-bisphosphate phosphatase 4 178 9.8E-81 T 05-07-2017 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 K08M4_RS11375 486ac498a1bf3c5130db385e853bbca6 183 SUPERFAMILY SSF56784 3 182 5.47E-47 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS11375 486ac498a1bf3c5130db385e853bbca6 183 Pfam PF13242 HAD-hyrolase-like 107 176 8.1E-12 T 05-07-2017 K08M4_RS03960 0d333ad4bbd022c7730ce690c6dafb60 85 Hamap MF_01217 Acyl carrier protein [acpP]. 8 82 14.031 T 05-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS03960 0d333ad4bbd022c7730ce690c6dafb60 85 Pfam PF00550 Phosphopantetheine attachment site 12 76 1.2E-12 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS03960 0d333ad4bbd022c7730ce690c6dafb60 85 SUPERFAMILY SSF47336 4 83 8.64E-19 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS03960 0d333ad4bbd022c7730ce690c6dafb60 85 Gene3D G3DSA:1.10.1200.10 4 83 4.2E-19 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS11300 9ced879370c919425926ca98d16d0399 86 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 1.6E-18 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS11300 9ced879370c919425926ca98d16d0399 86 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 29.376 T 05-07-2017 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS11300 9ced879370c919425926ca98d16d0399 86 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS11300 9ced879370c919425926ca98d16d0399 86 Pfam PF01197 Ribosomal protein L31 1 79 2.6E-26 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS11300 9ced879370c919425926ca98d16d0399 86 PRINTS PR01249 Ribosomal protein L31 signature 60 78 2.9E-15 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS11300 9ced879370c919425926ca98d16d0399 86 PRINTS PR01249 Ribosomal protein L31 signature 45 60 2.9E-15 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS11300 9ced879370c919425926ca98d16d0399 86 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.9E-15 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS11300 9ced879370c919425926ca98d16d0399 86 SUPERFAMILY SSF143800 1 81 4.71E-22 T 05-07-2017 K08M4_RS13995 27d750796e005d10eb3e567f063093de 316 Pfam PF05686 Glycosyl transferase family 90 134 279 1.7E-13 T 05-07-2017 IPR006598 Lipopolysaccharide-modifying protein K08M4_RS13995 27d750796e005d10eb3e567f063093de 316 SMART SM00672 72 305 8.3E-4 T 05-07-2017 IPR006598 Lipopolysaccharide-modifying protein K08M4_RS12555 7ebcafcc74a0a713845983e31cb75ac8 259 Pfam PF03799 Cell division protein FtsQ 126 238 1.5E-23 T 05-07-2017 IPR005548 Cell division protein FtsQ/DivIB K08M4_RS12555 7ebcafcc74a0a713845983e31cb75ac8 259 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 22 246 21.194 T 05-07-2017 IPR026579 Cell division protein FtsQ GO:0090529 K08M4_RS12555 7ebcafcc74a0a713845983e31cb75ac8 259 Pfam PF08478 POTRA domain, FtsQ-type 53 122 7.1E-16 T 05-07-2017 IPR013685 Polypeptide-transport-associated, FtsQ-type K08M4_RS02890 9a901c25d6d5fc1cc523835ad18b8b91 300 Gene3D G3DSA:3.40.50.620 170 218 1.4E-36 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS02890 9a901c25d6d5fc1cc523835ad18b8b91 300 Gene3D G3DSA:3.40.50.620 3 68 1.4E-36 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS02890 9a901c25d6d5fc1cc523835ad18b8b91 300 Gene3D G3DSA:3.90.800.10 69 168 5.6E-14 T 05-07-2017 K08M4_RS02890 9a901c25d6d5fc1cc523835ad18b8b91 300 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 3 269 1.4E-108 T 05-07-2017 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 K08M4_RS02890 9a901c25d6d5fc1cc523835ad18b8b91 300 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 3 288 38.665 T 05-07-2017 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 K08M4_RS02890 9a901c25d6d5fc1cc523835ad18b8b91 300 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 6 257 1.1E-39 T 05-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 K08M4_RS02890 9a901c25d6d5fc1cc523835ad18b8b91 300 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 2.0E-13 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 K08M4_RS02890 9a901c25d6d5fc1cc523835ad18b8b91 300 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 2.0E-13 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 K08M4_RS02890 9a901c25d6d5fc1cc523835ad18b8b91 300 PRINTS PR00987 Glutamyl-tRNA synthetase signature 184 192 2.0E-13 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 K08M4_RS02890 9a901c25d6d5fc1cc523835ad18b8b91 300 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 2.0E-13 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 K08M4_RS02890 9a901c25d6d5fc1cc523835ad18b8b91 300 PRINTS PR00987 Glutamyl-tRNA synthetase signature 168 178 2.0E-13 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 K08M4_RS02890 9a901c25d6d5fc1cc523835ad18b8b91 300 SUPERFAMILY SSF52374 3 284 2.31E-79 T 05-07-2017 K08M4_RS14215 585839d0886e3aa102a6b0347c4ca81a 267 SUPERFAMILY SSF54523 82 245 4.45E-56 T 05-07-2017 K08M4_RS14215 585839d0886e3aa102a6b0347c4ca81a 267 Pfam PF13633 Prokaryotic N-terminal methylation site 48 73 2.3E-11 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS14215 585839d0886e3aa102a6b0347c4ca81a 267 Gene3D G3DSA:3.10.610.10 79 192 3.2E-45 T 05-07-2017 K08M4_RS14215 585839d0886e3aa102a6b0347c4ca81a 267 Pfam PF11612 Type II secretion system (T2SS), protein J 100 237 1.5E-40 T 05-07-2017 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 K08M4_RS14215 585839d0886e3aa102a6b0347c4ca81a 267 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 48 70 2.0E-8 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS14215 585839d0886e3aa102a6b0347c4ca81a 267 TIGRFAM TIGR01711 gspJ: type II secretion system protein J 48 239 1.7E-79 T 05-07-2017 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 K08M4_RS14215 585839d0886e3aa102a6b0347c4ca81a 267 Gene3D G3DSA:2.10.70.20 194 242 8.2E-22 T 05-07-2017 K08M4_RS14215 585839d0886e3aa102a6b0347c4ca81a 267 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 48 68 - T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS18415 b1a952aaf5023c251c460e49a57433f5 279 Gene3D G3DSA:1.10.10.60 168 228 7.6E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS18415 b1a952aaf5023c251c460e49a57433f5 279 Pfam PF02311 AraC-like ligand binding domain 48 110 1.4E-5 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 K08M4_RS18415 b1a952aaf5023c251c460e49a57433f5 279 SUPERFAMILY SSF46689 228 277 2.51E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS18415 b1a952aaf5023c251c460e49a57433f5 279 SUPERFAMILY SSF46689 177 226 5.38E-5 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS18415 b1a952aaf5023c251c460e49a57433f5 279 SUPERFAMILY SSF51215 29 149 3.53E-19 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 K08M4_RS18415 b1a952aaf5023c251c460e49a57433f5 279 Gene3D G3DSA:2.60.120.280 19 114 2.4E-20 T 05-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 K08M4_RS18415 b1a952aaf5023c251c460e49a57433f5 279 Pfam PF12833 Helix-turn-helix domain 198 276 6.5E-19 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS18415 b1a952aaf5023c251c460e49a57433f5 279 SMART SM00342 192 275 9.7E-26 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS18415 b1a952aaf5023c251c460e49a57433f5 279 Gene3D G3DSA:1.10.10.60 229 277 8.2E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS15010 88939d59a9784a13b3a32bb8685502e5 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 211 4.4E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS15010 88939d59a9784a13b3a32bb8685502e5 223 SUPERFAMILY SSF161098 13 203 3.79E-43 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS15010 88939d59a9784a13b3a32bb8685502e5 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 112 1.7E-24 T 05-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 K08M4_RS15010 88939d59a9784a13b3a32bb8685502e5 223 Gene3D G3DSA:1.10.3720.10 14 219 6.5E-45 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS14990 dd51faf4681e3e8c91812dc87e97d8bf 85 Pfam PF01809 Haemolytic domain 11 75 3.1E-27 T 05-07-2017 IPR002696 Putative membrane protein insertion efficiency factor K08M4_RS14990 dd51faf4681e3e8c91812dc87e97d8bf 85 SMART SM01234 8 75 1.6E-38 T 05-07-2017 IPR002696 Putative membrane protein insertion efficiency factor K08M4_RS14990 dd51faf4681e3e8c91812dc87e97d8bf 85 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 8 76 23.793 T 05-07-2017 IPR002696 Putative membrane protein insertion efficiency factor K08M4_RS14990 dd51faf4681e3e8c91812dc87e97d8bf 85 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 16 82 2.9E-30 T 05-07-2017 IPR002696 Putative membrane protein insertion efficiency factor K08M4_RS14990 dd51faf4681e3e8c91812dc87e97d8bf 85 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 23 75 1.0E-23 T 05-07-2017 IPR002696 Putative membrane protein insertion efficiency factor K08M4_RS18790 dd43acfaf2660b8b208ae4c56ffcaa87 428 Pfam PF00270 DEAD/DEAH box helicase 32 209 2.1E-48 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS18790 dd43acfaf2660b8b208ae4c56ffcaa87 428 SMART SM00487 27 233 2.3E-57 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS18790 dd43acfaf2660b8b208ae4c56ffcaa87 428 Gene3D G3DSA:3.40.50.300 6 227 9.1E-79 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18790 dd43acfaf2660b8b208ae4c56ffcaa87 428 Gene3D G3DSA:3.40.50.300 228 387 1.7E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18790 dd43acfaf2660b8b208ae4c56ffcaa87 428 SMART SM00490 269 350 1.4E-32 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS18790 dd43acfaf2660b8b208ae4c56ffcaa87 428 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 166 174 - T 05-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site K08M4_RS18790 dd43acfaf2660b8b208ae4c56ffcaa87 428 Pfam PF00271 Helicase conserved C-terminal domain 245 350 1.0E-29 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS18790 dd43acfaf2660b8b208ae4c56ffcaa87 428 SUPERFAMILY SSF52540 88 371 3.18E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04635 06621faf02be2b4d427551971a7203c0 145 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 1 144 41.006 T 05-07-2017 IPR008228 Uncharacterised conserved protein UCP006173 K08M4_RS04635 06621faf02be2b4d427551971a7203c0 145 PIRSF PIRSF006173 1 144 5.9E-64 T 05-07-2017 IPR008228 Uncharacterised conserved protein UCP006173 K08M4_RS04635 06621faf02be2b4d427551971a7203c0 145 Pfam PF03692 Putative zinc- or iron-chelating domain 23 91 5.6E-8 T 05-07-2017 IPR005358 Putative zinc- or iron-chelating domain containing protein K08M4_RS04340 08e9e76108e90400838a68f70147a26c 412 Gene3D G3DSA:2.40.160.60 27 412 1.5E-126 T 05-07-2017 K08M4_RS04340 08e9e76108e90400838a68f70147a26c 412 SUPERFAMILY SSF56935 28 412 3.94E-89 T 05-07-2017 K08M4_RS04340 08e9e76108e90400838a68f70147a26c 412 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 19 412 1.7E-120 T 05-07-2017 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) K08M4_RS17435 8efbc4a10da18203d91a5327733af076 548 SUPERFAMILY SSF90123 7 304 1.44E-31 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS17435 8efbc4a10da18203d91a5327733af076 548 Pfam PF00664 ABC transporter transmembrane region 15 274 1.3E-12 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS17435 8efbc4a10da18203d91a5327733af076 548 Gene3D G3DSA:3.40.50.300 353 538 9.1E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17435 8efbc4a10da18203d91a5327733af076 548 Gene3D G3DSA:1.20.1560.10 7 307 2.1E-31 T 05-07-2017 K08M4_RS17435 8efbc4a10da18203d91a5327733af076 548 SUPERFAMILY SSF52540 366 537 4.51E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12660 80c533f0950dc19115fa271366a5d999 421 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 295 396 2.2E-40 T 05-07-2017 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 K08M4_RS12660 80c533f0950dc19115fa271366a5d999 421 SUPERFAMILY SSF81342 248 296 5.81E-93 T 05-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 K08M4_RS12660 80c533f0950dc19115fa271366a5d999 421 SUPERFAMILY SSF81342 6 221 5.81E-93 T 05-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 K08M4_RS12660 80c533f0950dc19115fa271366a5d999 421 Gene3D G3DSA:1.20.810.10 6 416 2.2E-157 T 05-07-2017 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 K08M4_RS12660 80c533f0950dc19115fa271366a5d999 421 PIRSF PIRSF038885 1 421 1.4E-152 T 05-07-2017 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 K08M4_RS12660 80c533f0950dc19115fa271366a5d999 421 SUPERFAMILY SSF81648 297 412 7.41E-33 T 05-07-2017 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 K08M4_RS12660 80c533f0950dc19115fa271366a5d999 421 Pfam PF00033 Cytochrome b/b6/petB 23 211 3.1E-66 T 05-07-2017 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 K08M4_RS07915 97e634fc0bc2bba4ef5dab4d0d7386b4 254 Pfam PF00005 ABC transporter 29 177 2.2E-38 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS07915 97e634fc0bc2bba4ef5dab4d0d7386b4 254 Gene3D G3DSA:3.40.50.300 13 249 5.8E-85 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07915 97e634fc0bc2bba4ef5dab4d0d7386b4 254 SUPERFAMILY SSF52540 13 247 1.52E-81 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07915 97e634fc0bc2bba4ef5dab4d0d7386b4 254 PIRSF PIRSF039085 10 253 4.2E-110 T 05-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 K08M4_RS07915 97e634fc0bc2bba4ef5dab4d0d7386b4 254 SMART SM00382 38 225 1.0E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS07915 97e634fc0bc2bba4ef5dab4d0d7386b4 254 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS01500 233d7dba5e80bcbbf8fbd8e046bd5917 136 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 58 69 - T 05-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01500 233d7dba5e80bcbbf8fbd8e046bd5917 136 SUPERFAMILY SSF54686 3 133 5.76E-52 T 05-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 K08M4_RS01500 233d7dba5e80bcbbf8fbd8e046bd5917 136 Pfam PF00252 Ribosomal protein L16p/L10e 4 131 4.8E-46 T 05-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 K08M4_RS01500 233d7dba5e80bcbbf8fbd8e046bd5917 136 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 4.9E-56 T 05-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01500 233d7dba5e80bcbbf8fbd8e046bd5917 136 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 133 36.976 T 05-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01500 233d7dba5e80bcbbf8fbd8e046bd5917 136 PRINTS PR00060 Ribosomal protein L16 signature 57 86 1.5E-39 T 05-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01500 233d7dba5e80bcbbf8fbd8e046bd5917 136 PRINTS PR00060 Ribosomal protein L16 signature 23 35 1.5E-39 T 05-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01500 233d7dba5e80bcbbf8fbd8e046bd5917 136 PRINTS PR00060 Ribosomal protein L16 signature 41 52 1.5E-39 T 05-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01500 233d7dba5e80bcbbf8fbd8e046bd5917 136 PRINTS PR00060 Ribosomal protein L16 signature 87 116 1.5E-39 T 05-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01500 233d7dba5e80bcbbf8fbd8e046bd5917 136 Gene3D G3DSA:3.90.1170.10 22 134 5.5E-53 T 05-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 K08M4_RS02785 dfb29278c310941eb8c7eb73c889a4ab 289 Pfam PF01478 Type IV leader peptidase family 135 244 1.7E-26 T 05-07-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 K08M4_RS02785 dfb29278c310941eb8c7eb73c889a4ab 289 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 17 124 1.5E-32 T 05-07-2017 IPR010627 Peptidase A24A, N-terminal K08M4_RS02785 dfb29278c310941eb8c7eb73c889a4ab 289 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 201 211 1.6E-29 T 05-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial K08M4_RS02785 dfb29278c310941eb8c7eb73c889a4ab 289 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 143 160 1.6E-29 T 05-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial K08M4_RS02785 dfb29278c310941eb8c7eb73c889a4ab 289 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 212 223 1.6E-29 T 05-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial K08M4_RS02785 dfb29278c310941eb8c7eb73c889a4ab 289 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 224 239 1.6E-29 T 05-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial K08M4_RS08025 975c51b9545cff5786934a3c01ba1d9d 298 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 6 295 3.6E-127 T 05-07-2017 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 K08M4_RS08025 975c51b9545cff5786934a3c01ba1d9d 298 SUPERFAMILY SSF51621 6 294 2.15E-96 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS08025 975c51b9545cff5786934a3c01ba1d9d 298 Gene3D G3DSA:3.20.20.60 5 292 3.7E-95 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS08025 975c51b9545cff5786934a3c01ba1d9d 298 ProSitePatterns PS00161 Isocitrate lyase signature. 119 124 - T 05-07-2017 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 K08M4_RS08025 975c51b9545cff5786934a3c01ba1d9d 298 Pfam PF13714 Phosphoenolpyruvate phosphomutase 10 259 1.5E-45 T 05-07-2017 K08M4_RS08025 975c51b9545cff5786934a3c01ba1d9d 298 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 3 296 49.983 T 05-07-2017 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 K08M4_RS07560 7de8dada9e4bbbc637d5a2d90964c4ce 406 ProSitePatterns PS01219 Ammonium transporters signature. 167 192 - T 05-07-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 K08M4_RS07560 7de8dada9e4bbbc637d5a2d90964c4ce 406 Gene3D G3DSA:1.10.3430.10 14 384 9.3E-96 T 05-07-2017 IPR029020 Ammonium/urea transporter K08M4_RS07560 7de8dada9e4bbbc637d5a2d90964c4ce 406 SUPERFAMILY SSF111352 17 384 3.27E-96 T 05-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 K08M4_RS07560 7de8dada9e4bbbc637d5a2d90964c4ce 406 Pfam PF00909 Ammonium Transporter Family 23 399 1.2E-87 T 05-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 K08M4_RS15390 ee8d66ef3871a0225db91c085ba143a7 377 Pfam PF07690 Major Facilitator Superfamily 19 340 9.4E-33 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS15390 ee8d66ef3871a0225db91c085ba143a7 377 Gene3D G3DSA:1.20.1250.20 4 188 3.2E-30 T 05-07-2017 K08M4_RS15390 ee8d66ef3871a0225db91c085ba143a7 377 Gene3D G3DSA:1.20.1250.20 201 367 2.3E-8 T 05-07-2017 K08M4_RS15390 ee8d66ef3871a0225db91c085ba143a7 377 SUPERFAMILY SSF103473 6 372 3.01E-48 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS14445 4cbd31c928dc381b6a0ad4ebf5685a75 427 SUPERFAMILY SSF116734 218 426 1.8E-25 T 05-07-2017 K08M4_RS14445 4cbd31c928dc381b6a0ad4ebf5685a75 427 SUPERFAMILY SSF116734 6 200 1.8E-24 T 05-07-2017 K08M4_RS14445 4cbd31c928dc381b6a0ad4ebf5685a75 427 Pfam PF01420 Type I restriction modification DNA specificity domain 49 184 3.2E-6 T 05-07-2017 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 K08M4_RS03350 90d9d9606fa0596b1c07e6c14a8e672b 249 Gene3D G3DSA:3.90.1210.10 46 102 8.3E-4 T 05-07-2017 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 K08M4_RS03350 90d9d9606fa0596b1c07e6c14a8e672b 249 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 113 215 1.0E-28 T 05-07-2017 IPR031571 Flp pilus assembly protein RcpC/CpaB domain K08M4_RS03350 90d9d9606fa0596b1c07e6c14a8e672b 249 SUPERFAMILY SSF51269 47 102 1.1E-5 T 05-07-2017 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 K08M4_RS03350 90d9d9606fa0596b1c07e6c14a8e672b 249 SMART SM00858 44 106 4.8E-8 T 05-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 K08M4_RS03350 90d9d9606fa0596b1c07e6c14a8e672b 249 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 8 227 7.3E-72 T 05-07-2017 IPR017592 Pilus assembly, Flp-type CpaB K08M4_RS03350 90d9d9606fa0596b1c07e6c14a8e672b 249 Pfam PF08666 SAF domain 45 102 4.4E-10 T 05-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 K08M4_RS11055 6e58881fbc66ab1db26ffa9cddc41c91 412 Pfam PF00860 Permease family 3 371 4.4E-92 T 05-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 K08M4_RS11055 6e58881fbc66ab1db26ffa9cddc41c91 412 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 4 395 1.2E-109 T 05-07-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 K08M4_RS11055 6e58881fbc66ab1db26ffa9cddc41c91 412 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 319 339 - T 05-07-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 K08M4_RS10005 521a4ba3ab5a122097794aa7d6efa608 172 PRINTS PR00179 Lipocalin signature 32 44 6.5E-7 T 05-07-2017 IPR002345 Lipocalin GO:0036094 K08M4_RS10005 521a4ba3ab5a122097794aa7d6efa608 172 PRINTS PR00179 Lipocalin signature 136 151 6.5E-7 T 05-07-2017 IPR002345 Lipocalin GO:0036094 K08M4_RS10005 521a4ba3ab5a122097794aa7d6efa608 172 PRINTS PR00179 Lipocalin signature 113 125 6.5E-7 T 05-07-2017 IPR002345 Lipocalin GO:0036094 K08M4_RS10005 521a4ba3ab5a122097794aa7d6efa608 172 Gene3D G3DSA:2.40.128.20 5 171 2.7E-56 T 05-07-2017 IPR012674 Calycin K08M4_RS10005 521a4ba3ab5a122097794aa7d6efa608 172 Pfam PF08212 Lipocalin-like domain 30 169 1.2E-43 T 05-07-2017 IPR000566 Lipocalin/cytosolic fatty-acid binding domain K08M4_RS10005 521a4ba3ab5a122097794aa7d6efa608 172 SUPERFAMILY SSF50814 4 171 2.59E-54 T 05-07-2017 IPR011038 Calycin-like K08M4_RS10005 521a4ba3ab5a122097794aa7d6efa608 172 PRINTS PR01171 Bacterial lipocalin signature 132 143 3.6E-38 T 05-07-2017 IPR002446 Lipocalin, bacterial GO:0005215 K08M4_RS10005 521a4ba3ab5a122097794aa7d6efa608 172 PRINTS PR01171 Bacterial lipocalin signature 65 74 3.6E-38 T 05-07-2017 IPR002446 Lipocalin, bacterial GO:0005215 K08M4_RS10005 521a4ba3ab5a122097794aa7d6efa608 172 PRINTS PR01171 Bacterial lipocalin signature 99 113 3.6E-38 T 05-07-2017 IPR002446 Lipocalin, bacterial GO:0005215 K08M4_RS10005 521a4ba3ab5a122097794aa7d6efa608 172 PRINTS PR01171 Bacterial lipocalin signature 29 43 3.6E-38 T 05-07-2017 IPR002446 Lipocalin, bacterial GO:0005215 K08M4_RS10005 521a4ba3ab5a122097794aa7d6efa608 172 PRINTS PR01171 Bacterial lipocalin signature 116 124 3.6E-38 T 05-07-2017 IPR002446 Lipocalin, bacterial GO:0005215 K08M4_RS10005 521a4ba3ab5a122097794aa7d6efa608 172 PRINTS PR01171 Bacterial lipocalin signature 46 62 3.6E-38 T 05-07-2017 IPR002446 Lipocalin, bacterial GO:0005215 K08M4_RS10005 521a4ba3ab5a122097794aa7d6efa608 172 PRINTS PR01171 Bacterial lipocalin signature 159 169 3.6E-38 T 05-07-2017 IPR002446 Lipocalin, bacterial GO:0005215 K08M4_RS10005 521a4ba3ab5a122097794aa7d6efa608 172 PIRSF PIRSF036893 1 172 5.6E-46 T 05-07-2017 IPR022271 Lipocalin, ApoD type K08M4_RS10005 521a4ba3ab5a122097794aa7d6efa608 172 ProSitePatterns PS00213 Lipocalin signature. 30 41 - T 05-07-2017 IPR022272 Lipocalin family conserved site K08M4_RS14905 8aa537d4615f0f443a2b8bc61b1e36b1 140 SUPERFAMILY SSF51344 5 87 4.45E-24 T 05-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 K08M4_RS14905 8aa537d4615f0f443a2b8bc61b1e36b1 140 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 85 1.1E-28 T 05-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 K08M4_RS14905 8aa537d4615f0f443a2b8bc61b1e36b1 140 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 134 4.8E-43 T 05-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 K08M4_RS14905 8aa537d4615f0f443a2b8bc61b1e36b1 140 SUPERFAMILY SSF46604 89 137 7.32E-13 T 05-07-2017 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210 K08M4_RS14905 8aa537d4615f0f443a2b8bc61b1e36b1 140 Gene3D G3DSA:2.60.15.10 5 92 8.2E-29 T 05-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 K08M4_RS14905 8aa537d4615f0f443a2b8bc61b1e36b1 140 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 89 134 2.6E-9 T 05-07-2017 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210 K08M4_RS14905 8aa537d4615f0f443a2b8bc61b1e36b1 140 Gene3D G3DSA:1.20.5.440 93 135 1.3E-21 T 05-07-2017 K08M4_RS14905 8aa537d4615f0f443a2b8bc61b1e36b1 140 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 4 132 20.013 T 05-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 K08M4_RS14905 8aa537d4615f0f443a2b8bc61b1e36b1 140 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 11 88 3.0E-37 T 05-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 K08M4_RS17360 8d21945ddc7fbe28091a572fae3a1ef0 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 36 - T 05-07-2017 IPR019844 Cold-shock conserved site K08M4_RS17360 8d21945ddc7fbe28091a572fae3a1ef0 69 PRINTS PR00050 Cold shock protein signature 42 60 5.4E-17 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS17360 8d21945ddc7fbe28091a572fae3a1ef0 69 PRINTS PR00050 Cold shock protein signature 7 22 5.4E-17 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS17360 8d21945ddc7fbe28091a572fae3a1ef0 69 PRINTS PR00050 Cold shock protein signature 27 36 5.4E-17 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS17360 8d21945ddc7fbe28091a572fae3a1ef0 69 SMART SM00357 6 69 5.6E-29 T 05-07-2017 IPR011129 Cold shock protein GO:0003676 K08M4_RS17360 8d21945ddc7fbe28091a572fae3a1ef0 69 SUPERFAMILY SSF50249 3 68 2.57E-23 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS17360 8d21945ddc7fbe28091a572fae3a1ef0 69 Pfam PF00313 'Cold-shock' DNA-binding domain 5 67 3.1E-28 T 05-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 K08M4_RS17360 8d21945ddc7fbe28091a572fae3a1ef0 69 Gene3D G3DSA:2.40.50.140 5 68 2.8E-29 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS17360 8d21945ddc7fbe28091a572fae3a1ef0 69 PIRSF PIRSF002599 1 69 1.1E-23 T 05-07-2017 IPR012156 Cold shock, CspA GO:0003676 K08M4_RS16910 32af4ace164772f106a41cfb4f9e88c0 574 Gene3D G3DSA:1.10.3720.10 304 548 3.3E-29 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS16910 32af4ace164772f106a41cfb4f9e88c0 574 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 392 562 6.0E-9 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS16910 32af4ace164772f106a41cfb4f9e88c0 574 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 287 4.3E-10 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS16910 32af4ace164772f106a41cfb4f9e88c0 574 SUPERFAMILY SSF161098 30 285 7.57E-46 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS16910 32af4ace164772f106a41cfb4f9e88c0 574 TIGRFAM TIGR03262 PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein 32 574 2.0E-249 T 05-07-2017 IPR017664 2-aminoethylphosphonate ABC transport system, permease protein, putative K08M4_RS16910 32af4ace164772f106a41cfb4f9e88c0 574 SUPERFAMILY SSF161098 309 556 6.02E-32 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS16910 32af4ace164772f106a41cfb4f9e88c0 574 Gene3D G3DSA:1.10.3720.10 34 289 7.4E-44 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS08555 c8ef09a89704e7aa7e983d9e6bc3007f 517 Gene3D G3DSA:3.40.50.410 359 481 3.6E-15 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS08555 c8ef09a89704e7aa7e983d9e6bc3007f 517 Gene3D G3DSA:3.40.50.410 242 308 3.6E-15 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS08555 c8ef09a89704e7aa7e983d9e6bc3007f 517 SUPERFAMILY SSF53300 242 305 2.92E-17 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS08555 c8ef09a89704e7aa7e983d9e6bc3007f 517 SUPERFAMILY SSF53300 354 467 2.92E-17 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS08555 c8ef09a89704e7aa7e983d9e6bc3007f 517 Pfam PF00092 von Willebrand factor type A domain 367 474 1.2E-8 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS08555 c8ef09a89704e7aa7e983d9e6bc3007f 517 SMART SM00327 238 483 1.0E-4 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS19600 bfbef46cecb80f1d0567cf1a40f56db4 342 SUPERFAMILY SSF53822 41 306 8.14E-36 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS19600 bfbef46cecb80f1d0567cf1a40f56db4 342 Gene3D G3DSA:3.40.50.2300 159 307 2.5E-23 T 05-07-2017 K08M4_RS19600 bfbef46cecb80f1d0567cf1a40f56db4 342 TIGRFAM TIGR02955 TMAO_TorT: TMAO reductase system periplasmic protein TorT 42 340 2.5E-131 T 05-07-2017 IPR014301 TMAO reductase system periplasmic, TorT K08M4_RS19600 bfbef46cecb80f1d0567cf1a40f56db4 342 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 41 319 1.1E-30 T 05-07-2017 IPR001761 Periplasmic binding protein/LacI sugar binding domain K08M4_RS19600 bfbef46cecb80f1d0567cf1a40f56db4 342 Gene3D G3DSA:3.40.50.2300 41 158 1.2E-13 T 05-07-2017 K08M4_RS18895 4261c62a19e14cfb8514801792c9f292 474 SUPERFAMILY SSF58104 164 473 4.58E-65 T 05-07-2017 K08M4_RS18895 4261c62a19e14cfb8514801792c9f292 474 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 339 368 2.2E-22 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS18895 4261c62a19e14cfb8514801792c9f292 474 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 233 262 2.2E-22 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS18895 4261c62a19e14cfb8514801792c9f292 474 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 310 337 2.2E-22 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS18895 4261c62a19e14cfb8514801792c9f292 474 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 274 471 5.7E-40 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS18895 4261c62a19e14cfb8514801792c9f292 474 Gene3D G3DSA:1.10.287.950 227 441 3.6E-51 T 05-07-2017 K08M4_RS18895 4261c62a19e14cfb8514801792c9f292 474 SMART SM00283 212 473 3.5E-51 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS11850 12ce8b43a0a28bd0e0d61b85ccf0b22f 311 Pfam PF13413 Helix-turn-helix domain 23 81 6.8E-18 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS11850 12ce8b43a0a28bd0e0d61b85ccf0b22f 311 Gene3D G3DSA:1.10.260.40 19 84 2.9E-7 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS11850 12ce8b43a0a28bd0e0d61b85ccf0b22f 311 Pfam PF13464 Domain of unknown function (DUF4115) 237 310 3.7E-25 T 05-07-2017 IPR025194 Domain of unknown function DUF4115 K08M4_RS11850 12ce8b43a0a28bd0e0d61b85ccf0b22f 311 SUPERFAMILY SSF47413 18 57 1.13E-5 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS16255 8647f43775cab6e3bacdd652613063b8 535 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 33 519 2.4E-164 T 05-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 K08M4_RS16255 8647f43775cab6e3bacdd652613063b8 535 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 73 520 2.1E-128 T 05-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 K08M4_RS16255 8647f43775cab6e3bacdd652613063b8 535 ProSitePatterns PS01303 BCCT family of transporters signature. 336 345 - T 05-07-2017 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 K08M4_RS17230 4e93d89552c7c6d97824e7a659879fdd 294 Gene3D G3DSA:1.10.10.10 7 87 5.9E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS17230 4e93d89552c7c6d97824e7a659879fdd 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 5.8E-9 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS17230 4e93d89552c7c6d97824e7a659879fdd 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 5.8E-9 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS17230 4e93d89552c7c6d97824e7a659879fdd 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 5.8E-9 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS17230 4e93d89552c7c6d97824e7a659879fdd 294 SUPERFAMILY SSF46785 6 114 2.1E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS17230 4e93d89552c7c6d97824e7a659879fdd 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 67 1.0E-17 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 SUPERFAMILY SSF55785 946 1044 4.38E-10 T 05-07-2017 IPR000014 PAS domain K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 SUPERFAMILY SSF52172 1306 1438 9.53E-33 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 Pfam PF00072 Response regulator receiver domain 1310 1415 8.5E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 SUPERFAMILY SSF53850 650 874 8.15E-28 T 05-07-2017 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 Gene3D G3DSA:3.40.190.10 654 743 8.2E-12 T 05-07-2017 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 Gene3D G3DSA:3.40.190.10 836 874 8.2E-12 T 05-07-2017 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 Gene3D G3DSA:3.40.190.10 230 268 1.4E-9 T 05-07-2017 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 Gene3D G3DSA:3.40.190.10 50 134 1.4E-9 T 05-07-2017 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 SUPERFAMILY SSF47226 1449 1544 1.28E-12 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1055 1120 4.3E-17 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 Gene3D G3DSA:3.40.50.2300 1305 1421 2.0E-35 T 05-07-2017 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 Pfam PF01627 Hpt domain 1479 1555 3.2E-5 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 SMART SM00448 1308 1419 1.1E-29 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 SMART SM00062 657 876 6.5E-7 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 Gene3D G3DSA:1.10.287.130 1061 1116 2.6E-15 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 SUPERFAMILY SSF55874 1109 1281 1.01E-43 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 SMART SM00387 1167 1285 2.4E-37 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 925 1042 9.5E-8 T 05-07-2017 IPR000014 PAS domain K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1243 1261 1.1E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1226 1236 1.1E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1267 1280 1.1E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1208 1222 1.1E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 Gene3D G3DSA:3.30.450.20 925 1060 6.8E-13 T 05-07-2017 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 Gene3D G3DSA:1.20.120.160 1455 1555 4.5E-13 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1167 1281 2.4E-26 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 SUPERFAMILY SSF53850 48 270 5.88E-23 T 05-07-2017 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 SMART SM00388 1055 1120 2.1E-20 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 SUPERFAMILY SSF53850 282 494 2.06E-10 T 05-07-2017 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 SUPERFAMILY SSF47384 1038 1121 1.06E-19 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 57 268 1.0E-17 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 658 873 5.6E-17 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS19670 488e5e5713c5e1cae2636ff7a8414c72 1640 Gene3D G3DSA:3.30.565.10 1127 1287 7.1E-43 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS06210 afd4ec4feaae75c7d8cec51735cd91ab 293 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 165 3.6E-38 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 K08M4_RS06210 afd4ec4feaae75c7d8cec51735cd91ab 293 PIRSF PIRSF000103 2 293 1.5E-66 T 05-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 K08M4_RS06210 afd4ec4feaae75c7d8cec51735cd91ab 293 SUPERFAMILY SSF51735 6 165 5.77E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS06210 afd4ec4feaae75c7d8cec51735cd91ab 293 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 8 21 - T 05-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 K08M4_RS06210 afd4ec4feaae75c7d8cec51735cd91ab 293 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 281 1.4E-18 T 05-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 K08M4_RS06210 afd4ec4feaae75c7d8cec51735cd91ab 293 SUPERFAMILY SSF48179 167 291 4.08E-28 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 K08M4_RS06210 afd4ec4feaae75c7d8cec51735cd91ab 293 Gene3D G3DSA:3.40.50.720 1 169 2.2E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS06210 afd4ec4feaae75c7d8cec51735cd91ab 293 Gene3D G3DSA:1.10.1040.10 170 291 2.6E-26 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 K08M4_RS16320 9e4af937a18909480efaed451db33b25 106 Gene3D G3DSA:3.30.70.860 26 98 1.7E-20 T 05-07-2017 K08M4_RS16320 9e4af937a18909480efaed451db33b25 106 Pfam PF04175 Protein of unknown function (DUF406) 8 95 7.0E-29 T 05-07-2017 IPR005272 Conserved hypothetical protein CHP00743 K08M4_RS17755 e13ae31a0be435a086038d22c218cc82 675 Gene3D G3DSA:2.120.10.30 549 636 8.0E-4 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like K08M4_RS17755 e13ae31a0be435a086038d22c218cc82 675 Gene3D G3DSA:2.120.10.30 396 515 8.0E-4 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like K08M4_RS17755 e13ae31a0be435a086038d22c218cc82 675 Pfam PF05787 Bacterial protein of unknown function (DUF839) 74 639 5.5E-157 T 05-07-2017 IPR008557 Protein of unknown function DUF839 K08M4_RS17755 e13ae31a0be435a086038d22c218cc82 675 SUPERFAMILY SSF101898 447 516 2.01E-8 T 05-07-2017 K08M4_RS17755 e13ae31a0be435a086038d22c218cc82 675 SUPERFAMILY SSF101898 549 634 2.01E-8 T 05-07-2017 K08M4_RS17755 e13ae31a0be435a086038d22c218cc82 675 SUPERFAMILY SSF101898 329 419 2.01E-8 T 05-07-2017 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 Gene3D G3DSA:3.90.700.10 234 351 4.8E-35 T 05-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 581 3.3E-235 T 05-07-2017 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 Pfam PF02910 Fumarate reductase flavoprotein C-term 453 581 3.0E-37 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 Gene3D G3DSA:1.20.58.100 427 537 2.8E-36 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 Pfam PF00890 FAD binding domain 7 397 3.5E-114 T 05-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 43 52 - T 05-07-2017 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 PIRSF PIRSF000171 1 572 2.4E-45 T 05-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 Gene3D G3DSA:3.50.50.60 2 233 7.4E-108 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 Gene3D G3DSA:3.50.50.60 353 417 7.4E-108 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 Gene3D G3DSA:4.10.80.40 543 577 3.1E-16 T 05-07-2017 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 360 382 8.4E-9 T 05-07-2017 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 8.4E-9 T 05-07-2017 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 SUPERFAMILY SSF46977 444 583 1.1E-43 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 TIGRFAM TIGR01176 fum_red_Fp: fumarate reductase (quinol), flavoprotein subunit 3 582 0.0 T 05-07-2017 IPR005884 Fumarate reductase, flavoprotein subunit GO:0009061|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.4|KEGG: 00620+1.3.5.4|KEGG: 00650+1.3.5.4|KEGG: 00720+1.3.5.4|MetaCyc: PWY-5392|MetaCyc: PWY-5913|MetaCyc: PWY-7384 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 8.6E-5 T 05-07-2017 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 375 382 8.6E-5 T 05-07-2017 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 SUPERFAMILY SSF51905 361 418 1.89E-73 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 SUPERFAMILY SSF51905 2 250 1.89E-73 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS13670 2b8711de6f8b171eae5611d860a1bb24 607 SUPERFAMILY SSF56425 227 358 2.69E-41 T 05-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS06530 4e30febbe3f2c5ed3c28ff71feb99ac6 253 Pfam PF02698 DUF218 domain 69 230 2.3E-24 T 05-07-2017 IPR003848 Domain of unknown function DUF218 K08M4_RS06530 4e30febbe3f2c5ed3c28ff71feb99ac6 253 Gene3D G3DSA:3.40.50.620 68 203 4.8E-20 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS18705 0631666e466faba1be511275ce0c590e 185 Pfam PF08274 PhnA Zinc-Ribbon 13 52 1.5E-9 T 05-07-2017 IPR013987 PhnA protein, N-terminal K08M4_RS18705 0631666e466faba1be511275ce0c590e 185 Pfam PF03831 PhnA domain 120 184 4.4E-21 T 05-07-2017 IPR013988 PhnA protein, C-terminal K08M4_RS18705 0631666e466faba1be511275ce0c590e 185 SMART SM00782 6 52 4.7E-27 T 05-07-2017 IPR013991 PhnA protein N-terminal, proteobacterial K08M4_RS18705 0631666e466faba1be511275ce0c590e 185 Gene3D G3DSA:2.30.30.40 120 184 8.3E-20 T 05-07-2017 K08M4_RS18705 0631666e466faba1be511275ce0c590e 185 SUPERFAMILY SSF82057 118 184 2.98E-19 T 05-07-2017 K08M4_RS08915 f4810e2d5f156752f1d0dead985d95e0 132 PIRSF PIRSF005087 1 132 1.5E-49 T 05-07-2017 IPR004465 Ribonucleotide reductase Class Ib, NrdI K08M4_RS08915 f4810e2d5f156752f1d0dead985d95e0 132 Hamap MF_00128 Protein NrdI [nrdI]. 1 131 32.875 T 05-07-2017 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial K08M4_RS08915 f4810e2d5f156752f1d0dead985d95e0 132 Pfam PF07972 NrdI Flavodoxin like 3 121 2.8E-44 T 05-07-2017 IPR004465 Ribonucleotide reductase Class Ib, NrdI K08M4_RS08915 f4810e2d5f156752f1d0dead985d95e0 132 SUPERFAMILY SSF52218 1 130 3.91E-23 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS08915 f4810e2d5f156752f1d0dead985d95e0 132 TIGRFAM TIGR00333 nrdI: nrdI protein 3 129 9.6E-46 T 05-07-2017 IPR004465 Ribonucleotide reductase Class Ib, NrdI K08M4_RS08915 f4810e2d5f156752f1d0dead985d95e0 132 Gene3D G3DSA:3.40.50.360 1 130 1.4E-50 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS09935 f7992a9543e9e09fc92c092136ac9013 286 SUPERFAMILY SSF103481 186 284 1.7E-10 T 05-07-2017 K08M4_RS09935 f7992a9543e9e09fc92c092136ac9013 286 Pfam PF00892 EamA-like transporter family 5 137 2.5E-14 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS09935 f7992a9543e9e09fc92c092136ac9013 286 Pfam PF00892 EamA-like transporter family 149 278 8.9E-15 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS09935 f7992a9543e9e09fc92c092136ac9013 286 SUPERFAMILY SSF103481 41 141 2.75E-9 T 05-07-2017 K08M4_RS03585 3fc2fc2f9ee9e1cc5cad1827ad6804fe 321 Gene3D G3DSA:3.20.20.70 53 313 1.1E-72 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS03585 3fc2fc2f9ee9e1cc5cad1827ad6804fe 321 TIGRFAM TIGR00510 lipA: lipoyl synthase 21 320 2.2E-150 T 05-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 K08M4_RS03585 3fc2fc2f9ee9e1cc5cad1827ad6804fe 321 Hamap MF_00206 Lipoyl synthase [lipA]. 1 321 154.451 T 05-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 K08M4_RS03585 3fc2fc2f9ee9e1cc5cad1827ad6804fe 321 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 25 73 2.4E-8 T 05-07-2017 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 K08M4_RS03585 3fc2fc2f9ee9e1cc5cad1827ad6804fe 321 SMART SM00729 84 293 5.0E-19 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 K08M4_RS03585 3fc2fc2f9ee9e1cc5cad1827ad6804fe 321 SUPERFAMILY SSF102114 52 315 9.55E-69 T 05-07-2017 K08M4_RS03585 3fc2fc2f9ee9e1cc5cad1827ad6804fe 321 PIRSF PIRSF005963 1 321 2.1E-129 T 05-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 K08M4_RS03585 3fc2fc2f9ee9e1cc5cad1827ad6804fe 321 Pfam PF04055 Radical SAM superfamily 91 251 2.2E-19 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS13035 ea70e1fdaf9cc5c6d18ed61c0b247f68 322 SUPERFAMILY SSF53850 25 321 4.26E-86 T 05-07-2017 K08M4_RS13035 ea70e1fdaf9cc5c6d18ed61c0b247f68 322 Gene3D G3DSA:3.40.190.10 118 250 4.1E-35 T 05-07-2017 K08M4_RS13035 ea70e1fdaf9cc5c6d18ed61c0b247f68 322 Pfam PF16868 NMT1-like family 30 319 2.3E-95 T 05-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family K08M4_RS13035 ea70e1fdaf9cc5c6d18ed61c0b247f68 322 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 11 319 9.4E-110 T 05-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family K08M4_RS13035 ea70e1fdaf9cc5c6d18ed61c0b247f68 322 Gene3D G3DSA:3.40.190.10 251 320 1.3E-65 T 05-07-2017 K08M4_RS13035 ea70e1fdaf9cc5c6d18ed61c0b247f68 322 Gene3D G3DSA:3.40.190.10 25 108 1.3E-65 T 05-07-2017 K08M4_RS06800 829a60b631c506f40593fa38ced62552 1276 Pfam PF12128 Protein of unknown function (DUF3584) 44 1244 7.3E-172 T 05-07-2017 IPR021979 Protein of unknown function DUF3584 K08M4_RS06800 829a60b631c506f40593fa38ced62552 1276 Gene3D G3DSA:3.40.1140.10 639 727 1.2E-6 T 05-07-2017 K08M4_RS06800 829a60b631c506f40593fa38ced62552 1276 Gene3D G3DSA:3.40.1140.10 42 138 1.2E-6 T 05-07-2017 K08M4_RS04425 627a678aa23d60e8b0c5bf9f323bcfd3 455 SUPERFAMILY SSF52540 235 406 9.26E-30 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04425 627a678aa23d60e8b0c5bf9f323bcfd3 455 Hamap MF_00900 GTPase HflX [hflX]. 31 425 38.903 T 05-07-2017 IPR016496 GTPase HflX GO:0005525 K08M4_RS04425 627a678aa23d60e8b0c5bf9f323bcfd3 455 Gene3D G3DSA:3.40.50.300 234 392 1.2E-26 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04425 627a678aa23d60e8b0c5bf9f323bcfd3 455 Pfam PF16360 GTP-binding GTPase Middle Region 156 231 7.1E-20 T 05-07-2017 IPR032305 GTP-binding protein, middle domain K08M4_RS04425 627a678aa23d60e8b0c5bf9f323bcfd3 455 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 115 392 7.0E-94 T 05-07-2017 IPR016496 GTPase HflX GO:0005525 K08M4_RS04425 627a678aa23d60e8b0c5bf9f323bcfd3 455 PIRSF PIRSF006809 2 455 1.1E-138 T 05-07-2017 IPR016496 GTPase HflX GO:0005525 K08M4_RS04425 627a678aa23d60e8b0c5bf9f323bcfd3 455 Pfam PF01926 50S ribosome-binding GTPase 237 355 1.7E-14 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS04425 627a678aa23d60e8b0c5bf9f323bcfd3 455 Pfam PF13167 GTP-binding GTPase N-terminal 29 153 1.7E-19 T 05-07-2017 IPR025121 GTPase HflX, N-terminal K08M4_RS04425 627a678aa23d60e8b0c5bf9f323bcfd3 455 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 237 257 1.3E-5 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS04425 627a678aa23d60e8b0c5bf9f323bcfd3 455 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 304 322 1.3E-5 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS14095 88eee7eb3e3c98f80b028a658e1814e8 233 Gene3D G3DSA:3.30.70.260 155 210 1.6E-26 T 05-07-2017 K08M4_RS14095 88eee7eb3e3c98f80b028a658e1814e8 233 SUPERFAMILY SSF100950 16 158 9.31E-27 T 05-07-2017 K08M4_RS14095 88eee7eb3e3c98f80b028a658e1814e8 233 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 63 226 1.7E-45 T 05-07-2017 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 K08M4_RS14095 88eee7eb3e3c98f80b028a658e1814e8 233 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 22 227 7.3E-52 T 05-07-2017 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 K08M4_RS14095 88eee7eb3e3c98f80b028a658e1814e8 233 Gene3D G3DSA:3.40.50.1360 16 154 1.2E-40 T 05-07-2017 K08M4_RS14095 88eee7eb3e3c98f80b028a658e1814e8 233 SUPERFAMILY SSF75445 141 212 2.35E-21 T 05-07-2017 K08M4_RS04450 c5d050372994477762a56025f1f0e0cd 332 Pfam PF13406 Transglycosylase SLT domain 31 327 3.1E-108 T 05-07-2017 IPR031304 Transglycosylase SLT domain 2 K08M4_RS04450 c5d050372994477762a56025f1f0e0cd 332 SUPERFAMILY SSF53955 26 330 1.41E-97 T 05-07-2017 IPR023346 Lysozyme-like domain K08M4_RS04450 c5d050372994477762a56025f1f0e0cd 332 Gene3D G3DSA:1.10.530.10 120 134 1.8E-4 T 05-07-2017 K08M4_RS04450 c5d050372994477762a56025f1f0e0cd 332 Gene3D G3DSA:1.10.530.10 179 212 1.8E-4 T 05-07-2017 K08M4_RS04450 c5d050372994477762a56025f1f0e0cd 332 Gene3D G3DSA:1.10.530.10 213 330 1.5E-57 T 05-07-2017 K08M4_RS04450 c5d050372994477762a56025f1f0e0cd 332 Gene3D G3DSA:1.10.530.10 76 119 1.5E-57 T 05-07-2017 K08M4_RS04450 c5d050372994477762a56025f1f0e0cd 332 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 31 330 1.2E-109 T 05-07-2017 IPR011970 Lytic murein transglycosylase K08M4_RS04780 2a9e7b46fa7d1159c5c57f9e0715f546 478 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 7 457 3.2E-162 T 05-07-2017 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 K08M4_RS04780 2a9e7b46fa7d1159c5c57f9e0715f546 478 Pfam PF03553 Na+/H+ antiporter family 161 453 1.4E-64 T 05-07-2017 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 K08M4_RS00475 f4051ba6911fd9d0f455c0d00dda8e8e 326 Gene3D G3DSA:3.40.50.1820 24 325 2.0E-39 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS00475 f4051ba6911fd9d0f455c0d00dda8e8e 326 SUPERFAMILY SSF53474 37 318 3.59E-35 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS00475 f4051ba6911fd9d0f455c0d00dda8e8e 326 Pfam PF12146 Serine aminopeptidase, S33 55 311 3.4E-55 T 05-07-2017 IPR022742 Serine aminopeptidase, S33 K08M4_RS17330 1af1837c6254b762f4104de3d67e0275 249 Pfam PF00899 ThiF family 12 245 9.4E-64 T 05-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 K08M4_RS17330 1af1837c6254b762f4104de3d67e0275 249 Gene3D G3DSA:3.40.50.720 5 249 4.8E-75 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS17330 1af1837c6254b762f4104de3d67e0275 249 SUPERFAMILY SSF69572 4 249 4.84E-83 T 05-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 K08M4_RS17330 1af1837c6254b762f4104de3d67e0275 249 TIGRFAM TIGR02355 moeB: molybdopterin synthase sulfurylase MoeB 8 248 6.0E-126 T 05-07-2017 IPR012730 Molybdopterin synthase sulfurylase MoeB GO:0006777 MetaCyc: PWY-6823 K08M4_RS21260 bc00f56cc16b7da4176e3b38638401a0 415 SUPERFAMILY SSF53850 34 411 1.09E-61 T 05-07-2017 K08M4_RS21260 bc00f56cc16b7da4176e3b38638401a0 415 Gene3D G3DSA:3.40.190.10 291 351 9.2E-33 T 05-07-2017 K08M4_RS21260 bc00f56cc16b7da4176e3b38638401a0 415 Gene3D G3DSA:3.40.190.10 26 145 9.2E-33 T 05-07-2017 K08M4_RS21260 bc00f56cc16b7da4176e3b38638401a0 415 Pfam PF13416 Bacterial extracellular solute-binding protein 46 346 2.2E-37 T 05-07-2017 K08M4_RS00015 c1c76327264b62db1d242666df2bd21f 359 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 355 8.4E-37 T 05-07-2017 IPR003395 RecF/RecN/SMC, N-terminal K08M4_RS00015 c1c76327264b62db1d242666df2bd21f 359 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 359 98.271 T 05-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 K08M4_RS00015 c1c76327264b62db1d242666df2bd21f 359 SUPERFAMILY SSF52540 1 355 3.06E-39 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00015 c1c76327264b62db1d242666df2bd21f 359 ProSitePatterns PS00618 RecF protein signature 2. 299 317 - T 05-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 K08M4_RS00015 c1c76327264b62db1d242666df2bd21f 359 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 356 1.9E-120 T 05-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 K08M4_RS00015 c1c76327264b62db1d242666df2bd21f 359 Gene3D G3DSA:3.40.50.300 231 350 1.5E-37 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00015 c1c76327264b62db1d242666df2bd21f 359 Gene3D G3DSA:3.40.50.300 1 172 1.5E-37 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00015 c1c76327264b62db1d242666df2bd21f 359 ProSitePatterns PS00617 RecF protein signature 1. 118 138 - T 05-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 K08M4_RS11985 64b932b275f8106ab1e7dfe9b72f7c96 247 Gene3D G3DSA:3.20.20.380 4 246 1.3E-84 T 05-07-2017 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 K08M4_RS11985 64b932b275f8106ab1e7dfe9b72f7c96 247 Hamap MF_00795 Copper homeostasis protein CutC [cutC]. 3 246 37.136 T 05-07-2017 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 K08M4_RS11985 64b932b275f8106ab1e7dfe9b72f7c96 247 Pfam PF03932 CutC family 4 205 4.3E-75 T 05-07-2017 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 K08M4_RS11985 64b932b275f8106ab1e7dfe9b72f7c96 247 SUPERFAMILY SSF110395 5 246 2.35E-68 T 05-07-2017 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 14 396 1.9E-91 T 05-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 PRINTS PR00714 Phosphomannose isomerase type I signature 271 290 1.7E-68 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 PRINTS PR00714 Phosphomannose isomerase type I signature 290 309 1.7E-68 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 PRINTS PR00714 Phosphomannose isomerase type I signature 236 251 1.7E-68 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 PRINTS PR00714 Phosphomannose isomerase type I signature 252 271 1.7E-68 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 PRINTS PR00714 Phosphomannose isomerase type I signature 19 37 1.7E-68 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 PRINTS PR00714 Phosphomannose isomerase type I signature 140 163 1.7E-68 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 PRINTS PR00714 Phosphomannose isomerase type I signature 95 116 1.7E-68 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 PRINTS PR00714 Phosphomannose isomerase type I signature 47 62 1.7E-68 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 140 148 - T 05-07-2017 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 Gene3D G3DSA:2.60.120.10 304 390 1.1E-8 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 ProSitePatterns PS00966 Phosphomannose isomerase type I signature 2. 271 296 - T 05-07-2017 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 Gene3D G3DSA:2.60.120.10 21 154 2.2E-65 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 Gene3D G3DSA:2.60.120.10 254 289 2.2E-65 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 Gene3D G3DSA:1.10.441.10 155 247 5.2E-30 T 05-07-2017 K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 Gene3D G3DSA:1.10.441.10 290 303 5.2E-30 T 05-07-2017 K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 SUPERFAMILY SSF51182 15 390 4.34E-100 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 PIRSF PIRSF001480 15 405 1.2E-101 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS20995 6113fcc34376743d7be235cf16338052 405 Pfam PF01238 Phosphomannose isomerase type I 18 372 1.1E-84 T 05-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 Gene3D G3DSA:1.10.8.280 286 406 5.5E-43 T 05-07-2017 K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 Gene3D G3DSA:3.30.1490.20 130 153 8.0E-28 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 Gene3D G3DSA:3.30.1490.20 200 248 8.0E-28 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 Pfam PF00005 ABC transporter 623 860 9.5E-10 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 SUPERFAMILY SSF52540 3 204 6.48E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 SUPERFAMILY SSF52540 430 569 6.48E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 Gene3D G3DSA:1.20.1580.10 407 477 8.0E-54 T 05-07-2017 K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 Gene3D G3DSA:1.20.1580.10 251 284 8.0E-54 T 05-07-2017 K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 Gene3D G3DSA:1.20.1580.10 91 129 8.0E-54 T 05-07-2017 K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 SUPERFAMILY SSF52540 621 913 2.54E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 Gene3D G3DSA:3.40.50.300 821 939 2.6E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 Gene3D G3DSA:3.40.50.300 2 51 7.4E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 Gene3D G3DSA:3.40.50.300 478 597 7.4E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 Gene3D G3DSA:3.40.50.300 605 672 2.6E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 Gene3D G3DSA:1.20.1580.10 694 820 3.2E-54 T 05-07-2017 K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 940 22.824 T 05-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 K08M4_RS13215 e9fd8889266c2d9993ca19108f1ef025 943 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 3 925 0.0 T 05-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 K08M4_RS14995 a42c5cad66d47cb9c99b966e7b3dfadb 118 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 7 113 7.8E-27 T 05-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 K08M4_RS14995 a42c5cad66d47cb9c99b966e7b3dfadb 118 SUPERFAMILY SSF54211 6 114 1.01E-29 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS14995 a42c5cad66d47cb9c99b966e7b3dfadb 118 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 6 115 17.327 T 05-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 K08M4_RS14995 a42c5cad66d47cb9c99b966e7b3dfadb 118 Pfam PF00825 Ribonuclease P 6 112 1.1E-31 T 05-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 K08M4_RS14995 a42c5cad66d47cb9c99b966e7b3dfadb 118 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 16 104 2.0E-43 T 05-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 K08M4_RS14995 a42c5cad66d47cb9c99b966e7b3dfadb 118 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 56 70 - T 05-07-2017 IPR020539 Ribonuclease P, conserved site GO:0004526 K08M4_RS14995 a42c5cad66d47cb9c99b966e7b3dfadb 118 Gene3D G3DSA:3.30.230.10 6 113 6.4E-32 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup K08M4_RS02365 20a9b41cb4c7e52296cfb398afa7496b 199 SUPERFAMILY SSF100950 5 198 1.67E-57 T 05-07-2017 K08M4_RS02365 20a9b41cb4c7e52296cfb398afa7496b 199 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 6 189 1.8E-52 T 05-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase K08M4_RS02365 20a9b41cb4c7e52296cfb398afa7496b 199 PIRSF PIRSF006806 1 192 5.7E-38 T 05-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase K08M4_RS02365 20a9b41cb4c7e52296cfb398afa7496b 199 Gene3D G3DSA:3.40.50.10420 6 195 2.4E-57 T 05-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain K08M4_RS02365 20a9b41cb4c7e52296cfb398afa7496b 199 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 7 189 1.2E-44 T 05-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase K08M4_RS21860 1aee0ae8a7799513b2a8e13837520ecc 186 SUPERFAMILY SSF143990 28 177 1.96E-51 T 05-07-2017 K08M4_RS21860 1aee0ae8a7799513b2a8e13837520ecc 186 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 36 176 2.6E-35 T 05-07-2017 IPR012816 NADAR K08M4_RS21860 1aee0ae8a7799513b2a8e13837520ecc 186 Pfam PF08719 Domain of unknown function (DUF1768) 38 176 2.3E-34 T 05-07-2017 IPR012816 NADAR K08M4_RS02505 29ae052e83953d31d5244909822686de 546 Pfam PF00117 Glutamine amidotransferase class-I 301 535 1.8E-63 T 05-07-2017 IPR017926 Glutamine amidotransferase K08M4_RS02505 29ae052e83953d31d5244909822686de 546 Gene3D G3DSA:3.40.50.880 288 538 2.6E-97 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS02505 29ae052e83953d31d5244909822686de 546 Pfam PF06418 CTP synthase N-terminus 5 265 1.7E-124 T 05-07-2017 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 K08M4_RS02505 29ae052e83953d31d5244909822686de 546 Gene3D G3DSA:3.40.50.300 1 280 2.0E-132 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02505 29ae052e83953d31d5244909822686de 546 SUPERFAMILY SSF52540 3 269 1.01E-120 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02505 29ae052e83953d31d5244909822686de 546 SUPERFAMILY SSF52317 289 539 1.33E-87 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS02505 29ae052e83953d31d5244909822686de 546 Hamap MF_01227 CTP synthase [pyrG]. 3 540 50.963 T 05-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 K08M4_RS02505 29ae052e83953d31d5244909822686de 546 TIGRFAM TIGR00337 PyrG: CTP synthase 2 535 2.6E-258 T 05-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 K08M4_RS20750 b09b976ed403a7988d5a929eb3d32af8 634 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 429 631 7.3E-44 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS20750 b09b976ed403a7988d5a929eb3d32af8 634 Pfam PF02743 Cache domain 36 264 3.3E-21 T 05-07-2017 IPR033479 Double Cache domain 1 K08M4_RS20750 b09b976ed403a7988d5a929eb3d32af8 634 Gene3D G3DSA:3.30.450.20 161 275 6.1E-14 T 05-07-2017 K08M4_RS20750 b09b976ed403a7988d5a929eb3d32af8 634 Gene3D G3DSA:1.10.287.950 388 603 1.6E-52 T 05-07-2017 K08M4_RS20750 b09b976ed403a7988d5a929eb3d32af8 634 SUPERFAMILY SSF103190 114 185 2.28E-9 T 05-07-2017 IPR029151 Periplasmic sensor domain-like K08M4_RS20750 b09b976ed403a7988d5a929eb3d32af8 634 Pfam PF00672 HAMP domain 283 352 1.5E-7 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS20750 b09b976ed403a7988d5a929eb3d32af8 634 SMART SM00304 391 451 97.0 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS20750 b09b976ed403a7988d5a929eb3d32af8 634 SMART SM00304 302 356 4.2E-6 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS20750 b09b976ed403a7988d5a929eb3d32af8 634 SMART SM00283 371 632 5.1E-59 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS20750 b09b976ed403a7988d5a929eb3d32af8 634 Gene3D G3DSA:3.30.450.20 91 160 1.6E-13 T 05-07-2017 K08M4_RS20750 b09b976ed403a7988d5a929eb3d32af8 634 SUPERFAMILY SSF58104 324 633 1.83E-70 T 05-07-2017 K08M4_RS05530 d646ed56cfc37fa94c9299ef105f0f48 338 SMART SM00382 56 189 2.2E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS05530 d646ed56cfc37fa94c9299ef105f0f48 338 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 258 331 2.0E-33 T 05-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 K08M4_RS05530 d646ed56cfc37fa94c9299ef105f0f48 338 Gene3D G3DSA:1.10.10.10 262 333 2.5E-35 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05530 d646ed56cfc37fa94c9299ef105f0f48 338 SUPERFAMILY SSF46785 262 335 7.71E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05530 d646ed56cfc37fa94c9299ef105f0f48 338 Gene3D G3DSA:1.10.8.60 188 260 1.5E-33 T 05-07-2017 K08M4_RS05530 d646ed56cfc37fa94c9299ef105f0f48 338 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 16 240 9.9E-117 T 05-07-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 K08M4_RS05530 d646ed56cfc37fa94c9299ef105f0f48 338 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 28 331 3.8E-147 T 05-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 K08M4_RS05530 d646ed56cfc37fa94c9299ef105f0f48 338 SUPERFAMILY SSF52540 25 256 1.9E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05530 d646ed56cfc37fa94c9299ef105f0f48 338 Gene3D G3DSA:3.40.50.300 25 182 4.3E-33 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05530 d646ed56cfc37fa94c9299ef105f0f48 338 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 338 183.195 T 05-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 K08M4_RS05530 d646ed56cfc37fa94c9299ef105f0f48 338 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 255 332 4.0E-38 T 05-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 158 180 3.5E-75 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 273 293 3.5E-75 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 209 235 3.5E-75 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 243 263 3.5E-75 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 293 309 3.5E-75 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 3.5E-75 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 131 148 3.5E-75 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 309 328 3.5E-75 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 54 628 7.2E-187 T 05-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 314 625 1.6E-66 T 05-07-2017 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 1 20 9.6E-9 T 05-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 188 203 9.6E-9 T 05-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 312 327 9.6E-9 T 05-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 112 135 9.6E-9 T 05-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 350 367 9.6E-9 T 05-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 618 631 9.6E-9 T 05-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS09055 04cacb68af2a808bece09abcf3eb663e 640 Pfam PF01578 Cytochrome C assembly protein 89 294 2.8E-42 T 05-07-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 K08M4_RS10880 59cd1aa450249eff3f831015f1a41109 188 Gene3D G3DSA:3.40.50.10190 122 187 3.9E-10 T 05-07-2017 IPR001357 BRCT domain K08M4_RS10880 59cd1aa450249eff3f831015f1a41109 188 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 122 187 3.2E-5 T 05-07-2017 IPR001357 BRCT domain K08M4_RS10880 59cd1aa450249eff3f831015f1a41109 188 SUPERFAMILY SSF52113 122 187 3.92E-9 T 05-07-2017 IPR001357 BRCT domain K08M4_RS18220 833310dacf3780bd50db0092b96fee9e 434 Pfam PF00375 Sodium:dicarboxylate symporter family 9 405 3.3E-130 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18220 833310dacf3780bd50db0092b96fee9e 434 Gene3D G3DSA:1.10.3860.10 3 411 1.9E-134 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18220 833310dacf3780bd50db0092b96fee9e 434 SUPERFAMILY SSF118215 9 407 3.01E-121 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18220 833310dacf3780bd50db0092b96fee9e 434 PRINTS PR00173 Glutamate-aspartate symporter signature 333 352 5.6E-48 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18220 833310dacf3780bd50db0092b96fee9e 434 PRINTS PR00173 Glutamate-aspartate symporter signature 56 76 5.6E-48 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18220 833310dacf3780bd50db0092b96fee9e 434 PRINTS PR00173 Glutamate-aspartate symporter signature 298 324 5.6E-48 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18220 833310dacf3780bd50db0092b96fee9e 434 PRINTS PR00173 Glutamate-aspartate symporter signature 7 27 5.6E-48 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18220 833310dacf3780bd50db0092b96fee9e 434 PRINTS PR00173 Glutamate-aspartate symporter signature 86 111 5.6E-48 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18220 833310dacf3780bd50db0092b96fee9e 434 PRINTS PR00173 Glutamate-aspartate symporter signature 360 380 5.6E-48 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18220 833310dacf3780bd50db0092b96fee9e 434 PRINTS PR00173 Glutamate-aspartate symporter signature 196 215 5.6E-48 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18065 833310dacf3780bd50db0092b96fee9e 434 Pfam PF00375 Sodium:dicarboxylate symporter family 9 405 3.3E-130 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18065 833310dacf3780bd50db0092b96fee9e 434 Gene3D G3DSA:1.10.3860.10 3 411 1.9E-134 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18065 833310dacf3780bd50db0092b96fee9e 434 SUPERFAMILY SSF118215 9 407 3.01E-121 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18065 833310dacf3780bd50db0092b96fee9e 434 PRINTS PR00173 Glutamate-aspartate symporter signature 333 352 5.6E-48 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18065 833310dacf3780bd50db0092b96fee9e 434 PRINTS PR00173 Glutamate-aspartate symporter signature 56 76 5.6E-48 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18065 833310dacf3780bd50db0092b96fee9e 434 PRINTS PR00173 Glutamate-aspartate symporter signature 298 324 5.6E-48 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18065 833310dacf3780bd50db0092b96fee9e 434 PRINTS PR00173 Glutamate-aspartate symporter signature 7 27 5.6E-48 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18065 833310dacf3780bd50db0092b96fee9e 434 PRINTS PR00173 Glutamate-aspartate symporter signature 86 111 5.6E-48 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18065 833310dacf3780bd50db0092b96fee9e 434 PRINTS PR00173 Glutamate-aspartate symporter signature 360 380 5.6E-48 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS18065 833310dacf3780bd50db0092b96fee9e 434 PRINTS PR00173 Glutamate-aspartate symporter signature 196 215 5.6E-48 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 Pfam PF00575 S1 RNA binding domain 620 691 1.0E-19 T 05-07-2017 IPR003029 S1 domain GO:0003676 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 Gene3D G3DSA:3.30.1370.10 553 618 2.1E-25 T 05-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 SUPERFAMILY SSF55666 146 236 4.35E-28 T 05-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 Pfam PF01138 3' exoribonuclease family, domain 1 17 145 1.6E-18 T 05-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 Pfam PF01138 3' exoribonuclease family, domain 1 325 457 3.2E-20 T 05-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 SUPERFAMILY SSF54211 5 145 1.01E-47 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 SUPERFAMILY SSF46915 239 321 2.48E-19 T 05-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 321 9.0E-24 T 05-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 11 692 0.0 T 05-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 SMART SM00322 553 618 7.1E-12 T 05-07-2017 IPR004087 K Homology domain GO:0003676 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 SMART SM00316 621 691 3.2E-26 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 Gene3D G3DSA:2.40.50.140 619 693 3.8E-27 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 Pfam PF00013 KH domain 557 615 2.9E-9 T 05-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 SUPERFAMILY SSF55666 451 550 1.54E-27 T 05-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 Gene3D G3DSA:3.30.230.70 315 543 2.2E-88 T 05-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 Gene3D G3DSA:3.30.230.70 3 226 1.1E-79 T 05-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 694 29.999 T 05-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 PIRSF PIRSF005499 2 706 1.2E-294 T 05-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 Gene3D G3DSA:1.10.10.400 227 314 9.9E-25 T 05-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 SUPERFAMILY SSF54791 553 630 6.92E-16 T 05-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 SUPERFAMILY SSF50249 607 694 2.74E-21 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 SUPERFAMILY SSF54211 300 493 2.89E-46 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS03145 cc3fab98ddacd0c02fca3390cfd1d015 706 Pfam PF03725 3' exoribonuclease family, domain 2 148 211 5.7E-12 T 05-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 K08M4_RS13665 241612e7a0440e83c6ec4e873d48e728 323 Gene3D G3DSA:3.30.930.10 11 319 3.6E-71 T 05-07-2017 K08M4_RS13665 241612e7a0440e83c6ec4e873d48e728 323 Pfam PF00152 tRNA synthetases class II (D, K and N) 2 319 6.1E-46 T 05-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS13665 241612e7a0440e83c6ec4e873d48e728 323 SUPERFAMILY SSF55681 10 321 8.36E-82 T 05-07-2017 K08M4_RS13665 241612e7a0440e83c6ec4e873d48e728 323 Hamap MF_00174 Elongation factor P--(R)-beta-lysine ligase [epmA]. 1 323 52.554 T 05-07-2017 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 K08M4_RS13665 241612e7a0440e83c6ec4e873d48e728 323 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 14 318 2.4E-128 T 05-07-2017 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 K08M4_RS15980 5dff74afc81345c08ed161f8af37f439 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 305 7.2E-23 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS15980 5dff74afc81345c08ed161f8af37f439 309 Gene3D G3DSA:1.10.3720.10 43 307 1.0E-39 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS15980 5dff74afc81345c08ed161f8af37f439 309 SUPERFAMILY SSF161098 33 304 2.49E-35 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS15980 5dff74afc81345c08ed161f8af37f439 309 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 32 306 3.5E-90 T 05-07-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 K08M4_RS04950 a040581b92026591a03261dcff827098 543 Gene3D G3DSA:3.10.105.10 312 511 5.6E-62 T 05-07-2017 K08M4_RS04950 a040581b92026591a03261dcff827098 543 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 462 1.1E-93 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain K08M4_RS04950 a040581b92026591a03261dcff827098 543 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 88 109 - T 05-07-2017 IPR023765 Solute-binding protein family 5, conserved site K08M4_RS04950 a040581b92026591a03261dcff827098 543 Gene3D G3DSA:3.90.76.10 50 217 2.9E-50 T 05-07-2017 K08M4_RS04950 a040581b92026591a03261dcff827098 543 PIRSF PIRSF002741 1 543 1.7E-115 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 K08M4_RS04950 a040581b92026591a03261dcff827098 543 Gene3D G3DSA:3.40.190.10 218 311 2.2E-31 T 05-07-2017 K08M4_RS04950 a040581b92026591a03261dcff827098 543 SUPERFAMILY SSF53850 37 535 3.44E-145 T 05-07-2017 K08M4_RS14655 51ca7e75f82e65f850ae231cd164ae01 368 Gene3D G3DSA:2.40.50.100 70 102 3.2E-12 T 05-07-2017 K08M4_RS14655 51ca7e75f82e65f850ae231cd164ae01 368 Gene3D G3DSA:2.40.50.100 163 194 3.2E-12 T 05-07-2017 K08M4_RS14655 51ca7e75f82e65f850ae231cd164ae01 368 SUPERFAMILY SSF111369 58 273 1.7E-39 T 05-07-2017 K08M4_RS14655 51ca7e75f82e65f850ae231cd164ae01 368 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 64 269 2.5E-24 T 05-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain K08M4_RS14655 51ca7e75f82e65f850ae231cd164ae01 368 Pfam PF00529 HlyD membrane-fusion protein of T1SS 116 339 5.3E-7 T 05-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 K08M4_RS14655 51ca7e75f82e65f850ae231cd164ae01 368 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 353 1.6E-74 T 05-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 K08M4_RS11100 cbdba8dc7bccd72d80965cddc8cf03da 154 Pfam PF00075 RNase H 3 141 4.0E-52 T 05-07-2017 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 K08M4_RS11100 cbdba8dc7bccd72d80965cddc8cf03da 154 Hamap MF_00042 Ribonuclease H [rnhA]. 2 150 36.257 T 05-07-2017 IPR022892 Ribonuclease H GO:0004523 K08M4_RS11100 cbdba8dc7bccd72d80965cddc8cf03da 154 Gene3D G3DSA:3.30.420.10 2 149 3.2E-59 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS11100 cbdba8dc7bccd72d80965cddc8cf03da 154 SUPERFAMILY SSF53098 3 143 3.54E-57 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS05975 5d2b83d7d17d43a219d8b685b2857544 794 Gene3D G3DSA:3.40.50.300 188 335 9.4E-15 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05975 5d2b83d7d17d43a219d8b685b2857544 794 Pfam PF00271 Helicase conserved C-terminal domain 200 323 1.0E-13 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS05975 5d2b83d7d17d43a219d8b685b2857544 794 Pfam PF04408 Helicase associated domain (HA2) 382 440 1.6E-5 T 05-07-2017 IPR007502 Helicase-associated domain GO:0004386 K08M4_RS05975 5d2b83d7d17d43a219d8b685b2857544 794 SUPERFAMILY SSF52540 19 151 8.15E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05975 5d2b83d7d17d43a219d8b685b2857544 794 SUPERFAMILY SSF52540 180 335 8.15E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05975 5d2b83d7d17d43a219d8b685b2857544 794 SMART SM00487 2 174 3.2E-16 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS05975 5d2b83d7d17d43a219d8b685b2857544 794 Pfam PF00270 DEAD/DEAH box helicase 13 149 3.5E-7 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS05975 5d2b83d7d17d43a219d8b685b2857544 794 SMART SM00490 219 324 9.9E-15 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS05975 5d2b83d7d17d43a219d8b685b2857544 794 Gene3D G3DSA:3.40.50.300 4 150 9.0E-37 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15660 539022bcdbc9a958d415a257ee8c5454 609 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 514 574 6.2E-9 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS15660 539022bcdbc9a958d415a257ee8c5454 609 Gene3D G3DSA:3.40.50.270 514 604 2.0E-16 T 05-07-2017 K08M4_RS15660 539022bcdbc9a958d415a257ee8c5454 609 SUPERFAMILY SSF52794 512 605 4.19E-15 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS15660 539022bcdbc9a958d415a257ee8c5454 609 Pfam PF03611 PTS system sugar-specific permease component 15 416 2.4E-121 T 05-07-2017 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 K08M4_RS15660 539022bcdbc9a958d415a257ee8c5454 609 PIRSF PIRSF037343 1 607 5.1E-262 T 05-07-2017 IPR017180 Phosphotransferase system component IIBC, sugar-specific, predicted K08M4_RS20475 bfa76d9d194e996ab42b059183a10982 452 Pfam PF03553 Na+/H+ antiporter family 15 222 1.2E-12 T 05-07-2017 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 K08M4_RS14885 9a1d252e4341c2e42d42586978a41fd8 514 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 29 316 4.4E-81 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme K08M4_RS14885 9a1d252e4341c2e42d42586978a41fd8 514 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 15 513 6.4E-250 T 05-07-2017 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 K08M4_RS14885 9a1d252e4341c2e42d42586978a41fd8 514 SUPERFAMILY SSF55021 420 513 3.66E-27 T 05-07-2017 K08M4_RS14885 9a1d252e4341c2e42d42586978a41fd8 514 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 329 419 2.0E-25 T 05-07-2017 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 K08M4_RS14885 9a1d252e4341c2e42d42586978a41fd8 514 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 427 513 4.4E-26 T 05-07-2017 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 K08M4_RS14885 9a1d252e4341c2e42d42586978a41fd8 514 SUPERFAMILY SSF53686 15 365 2.75E-105 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme K08M4_RS14885 9a1d252e4341c2e42d42586978a41fd8 514 Gene3D G3DSA:3.40.50.1100 61 157 5.9E-38 T 05-07-2017 K08M4_RS14885 9a1d252e4341c2e42d42586978a41fd8 514 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 53 66 - T 05-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 K08M4_RS14885 9a1d252e4341c2e42d42586978a41fd8 514 Gene3D G3DSA:3.40.1020.10 221 388 7.7E-48 T 05-07-2017 K08M4_RS14885 9a1d252e4341c2e42d42586978a41fd8 514 Gene3D G3DSA:3.40.1020.10 389 513 2.9E-45 T 05-07-2017 K08M4_RS01940 fc8122c16f93e57aa52377d911289b88 506 SUPERFAMILY SSF52949 1 184 2.77E-52 T 05-07-2017 K08M4_RS01940 fc8122c16f93e57aa52377d911289b88 506 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 187 489 2.7E-117 T 05-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 K08M4_RS01940 fc8122c16f93e57aa52377d911289b88 506 SUPERFAMILY SSF53187 179 496 3.45E-123 T 05-07-2017 K08M4_RS01940 fc8122c16f93e57aa52377d911289b88 506 Gene3D G3DSA:3.40.630.10 171 500 6.5E-138 T 05-07-2017 K08M4_RS01940 fc8122c16f93e57aa52377d911289b88 506 PRINTS PR00481 Cytosol aminopeptidase signature 345 365 5.0E-55 T 05-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 K08M4_RS01940 fc8122c16f93e57aa52377d911289b88 506 PRINTS PR00481 Cytosol aminopeptidase signature 286 307 5.0E-55 T 05-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 K08M4_RS01940 fc8122c16f93e57aa52377d911289b88 506 PRINTS PR00481 Cytosol aminopeptidase signature 323 344 5.0E-55 T 05-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 K08M4_RS01940 fc8122c16f93e57aa52377d911289b88 506 PRINTS PR00481 Cytosol aminopeptidase signature 373 388 5.0E-55 T 05-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 K08M4_RS01940 fc8122c16f93e57aa52377d911289b88 506 PRINTS PR00481 Cytosol aminopeptidase signature 264 281 5.0E-55 T 05-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 K08M4_RS01940 fc8122c16f93e57aa52377d911289b88 506 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 349 356 - T 05-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 K08M4_RS01940 fc8122c16f93e57aa52377d911289b88 506 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 147 3.7E-34 T 05-07-2017 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 K08M4_RS01940 fc8122c16f93e57aa52377d911289b88 506 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 497 40.658 T 05-07-2017 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 K08M4_RS01940 fc8122c16f93e57aa52377d911289b88 506 Gene3D G3DSA:3.40.220.10 1 161 3.9E-68 T 05-07-2017 K08M4_RS00950 f5db2d063cac80dfc27a75774d4d5c09 398 PIRSF PIRSF004925 2 389 5.2E-102 T 05-07-2017 IPR026032 Probable 3-phenylpropionic acid transporter K08M4_RS00950 f5db2d063cac80dfc27a75774d4d5c09 398 Pfam PF12832 MFS_1 like family 13 361 1.3E-39 T 05-07-2017 IPR024989 Major facilitator superfamily associated domain K08M4_RS00950 f5db2d063cac80dfc27a75774d4d5c09 398 Gene3D G3DSA:1.20.1250.20 199 383 1.8E-17 T 05-07-2017 K08M4_RS00950 f5db2d063cac80dfc27a75774d4d5c09 398 SUPERFAMILY SSF103473 9 373 4.32E-32 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS00950 f5db2d063cac80dfc27a75774d4d5c09 398 Gene3D G3DSA:1.20.1250.20 13 181 8.8E-14 T 05-07-2017 K08M4_RS07090 99dd1665544036ce678fe456bb62863e 138 PRINTS PR00502 NUDIX hydrolase family signature 47 62 4.3E-7 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 K08M4_RS07090 99dd1665544036ce678fe456bb62863e 138 PRINTS PR00502 NUDIX hydrolase family signature 33 47 4.3E-7 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 K08M4_RS07090 99dd1665544036ce678fe456bb62863e 138 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 K08M4_RS07090 99dd1665544036ce678fe456bb62863e 138 Pfam PF00293 NUDIX domain 6 118 2.5E-24 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 K08M4_RS07090 99dd1665544036ce678fe456bb62863e 138 SUPERFAMILY SSF55811 5 124 4.06E-34 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS07090 99dd1665544036ce678fe456bb62863e 138 Gene3D G3DSA:3.90.79.10 4 120 2.6E-38 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 Pfam PF00512 His Kinase A (phospho-acceptor) domain 343 407 2.3E-16 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 Gene3D G3DSA:3.40.50.2300 586 707 6.1E-32 T 05-07-2017 K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 SUPERFAMILY SSF52172 586 715 2.28E-29 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 Pfam PF00072 Response regulator receiver domain 590 702 2.7E-19 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 SMART SM00387 454 569 1.5E-37 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 Pfam PF00672 HAMP domain 266 324 6.9E-7 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 Gene3D G3DSA:3.30.450.20 105 187 1.5E-8 T 05-07-2017 K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 Gene3D G3DSA:3.30.565.10 393 568 4.2E-46 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 455 566 1.2E-28 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 SUPERFAMILY SSF55874 396 569 9.04E-44 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 SMART SM00448 588 702 1.4E-22 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 SMART SM00388 342 407 7.9E-22 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 SUPERFAMILY SSF47384 330 408 1.0E-17 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 Gene3D G3DSA:1.10.287.130 336 392 8.9E-14 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 547 1.9E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 508 1.9E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 522 1.9E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS05635 7f0d895b03a55e24759e48e21aebd5ce 818 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 566 1.9E-16 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS03505 3bac93b1b9b9ee5fe37fb85e730ada9e 369 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 37.86 T 05-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS03505 3bac93b1b9b9ee5fe37fb85e730ada9e 369 Gene3D G3DSA:3.90.870.10 2 211 4.9E-97 T 05-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain K08M4_RS03505 3bac93b1b9b9ee5fe37fb85e730ada9e 369 Pfam PF00925 GTP cyclohydrolase II 207 367 1.1E-40 T 05-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 K08M4_RS03505 3bac93b1b9b9ee5fe37fb85e730ada9e 369 PIRSF PIRSF001259 3 369 2.8E-128 T 05-07-2017 K08M4_RS03505 3bac93b1b9b9ee5fe37fb85e730ada9e 369 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 7 199 2.0E-73 T 05-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS03505 3bac93b1b9b9ee5fe37fb85e730ada9e 369 SUPERFAMILY SSF142695 205 367 1.44E-47 T 05-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 K08M4_RS03505 3bac93b1b9b9ee5fe37fb85e730ada9e 369 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 198 1.5E-81 T 05-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS03505 3bac93b1b9b9ee5fe37fb85e730ada9e 369 SUPERFAMILY SSF55821 3 202 1.58E-84 T 05-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain K08M4_RS02320 aa0afe649e383c8476521c9347c44d23 349 Gene3D G3DSA:3.30.360.10 173 327 1.2E-61 T 05-07-2017 K08M4_RS02320 aa0afe649e383c8476521c9347c44d23 349 SUPERFAMILY SSF55347 164 326 1.52E-58 T 05-07-2017 K08M4_RS02320 aa0afe649e383c8476521c9347c44d23 349 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 169 325 5.0E-55 T 05-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02320 aa0afe649e383c8476521c9347c44d23 349 SMART SM00846 2 164 1.5E-66 T 05-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02320 aa0afe649e383c8476521c9347c44d23 349 Hamap MF_01640 D-erythrose-4-phosphate dehydrogenase [epd]. 1 346 65.128 T 05-07-2017 IPR006422 D-erythrose-4-phosphate dehydrogenase GO:0005737|GO:0042823|GO:0048001|GO:0051287|GO:0055114 KEGG: 00750+1.2.1.72 K08M4_RS02320 aa0afe649e383c8476521c9347c44d23 349 PIRSF PIRSF000149 1 346 8.6E-124 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02320 aa0afe649e383c8476521c9347c44d23 349 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 281 296 2.1E-29 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02320 aa0afe649e383c8476521c9347c44d23 349 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 158 176 2.1E-29 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02320 aa0afe649e383c8476521c9347c44d23 349 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 241 258 2.1E-29 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02320 aa0afe649e383c8476521c9347c44d23 349 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 185 201 2.1E-29 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02320 aa0afe649e383c8476521c9347c44d23 349 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 121 134 2.1E-29 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS02320 aa0afe649e383c8476521c9347c44d23 349 TIGRFAM TIGR01532 E4PD_g-proteo: erythrose-4-phosphate dehydrogenase 3 337 7.7E-189 T 05-07-2017 IPR006422 D-erythrose-4-phosphate dehydrogenase GO:0005737|GO:0042823|GO:0048001|GO:0051287|GO:0055114 KEGG: 00750+1.2.1.72 K08M4_RS02320 aa0afe649e383c8476521c9347c44d23 349 SUPERFAMILY SSF51735 2 188 1.69E-48 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS02320 aa0afe649e383c8476521c9347c44d23 349 Gene3D G3DSA:3.40.50.720 1 172 1.8E-63 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS02320 aa0afe649e383c8476521c9347c44d23 349 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 164 9.7E-46 T 05-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS07890 4c298bb56284a1fa19c4b96bdc083674 160 Gene3D G3DSA:3.30.70.990 9 94 1.5E-30 T 05-07-2017 K08M4_RS07890 4c298bb56284a1fa19c4b96bdc083674 160 SUPERFAMILY SSF89963 2 81 9.29E-30 T 05-07-2017 IPR007551 Protein of unknown function DUF520 K08M4_RS07890 4c298bb56284a1fa19c4b96bdc083674 160 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 160 29.878 T 05-07-2017 IPR007551 Protein of unknown function DUF520 K08M4_RS07890 4c298bb56284a1fa19c4b96bdc083674 160 Gene3D G3DSA:3.30.70.860 95 160 2.8E-35 T 05-07-2017 K08M4_RS07890 4c298bb56284a1fa19c4b96bdc083674 160 SUPERFAMILY SSF89963 88 160 2.09E-30 T 05-07-2017 IPR007551 Protein of unknown function DUF520 K08M4_RS07890 4c298bb56284a1fa19c4b96bdc083674 160 Pfam PF04461 Protein of unknown function (DUF520) 2 159 9.6E-65 T 05-07-2017 IPR007551 Protein of unknown function DUF520 K08M4_RS12665 d9d69988aa524ed61b999686088dcf30 196 Gene3D G3DSA:2.102.10.10 45 193 2.9E-34 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 K08M4_RS12665 d9d69988aa524ed61b999686088dcf30 196 Pfam PF00355 Rieske [2Fe-2S] domain 53 174 6.3E-12 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 K08M4_RS12665 d9d69988aa524ed61b999686088dcf30 196 SUPERFAMILY SSF50022 30 191 4.0E-42 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 K08M4_RS12665 d9d69988aa524ed61b999686088dcf30 196 Gene3D G3DSA:1.20.5.510 8 40 1.7E-6 T 05-07-2017 K08M4_RS12665 d9d69988aa524ed61b999686088dcf30 196 PRINTS PR00162 Rieske 2Fe-2S subunit signature 162 174 3.0E-7 T 05-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 K08M4_RS12665 d9d69988aa524ed61b999686088dcf30 196 PRINTS PR00162 Rieske 2Fe-2S subunit signature 149 161 3.0E-7 T 05-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 K08M4_RS12665 d9d69988aa524ed61b999686088dcf30 196 PRINTS PR00162 Rieske 2Fe-2S subunit signature 119 130 3.0E-7 T 05-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 K08M4_RS12665 d9d69988aa524ed61b999686088dcf30 196 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 9 190 1.1E-73 T 05-07-2017 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 K08M4_RS12665 d9d69988aa524ed61b999686088dcf30 196 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 4 40 2.6E-15 T 05-07-2017 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 K08M4_RS21110 aaf6d119f0f98f8473dbf7c1f038630b 219 Gene3D G3DSA:3.40.50.1000 90 216 1.4E-42 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS21110 aaf6d119f0f98f8473dbf7c1f038630b 219 Gene3D G3DSA:3.40.50.1000 1 17 1.4E-42 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS21110 aaf6d119f0f98f8473dbf7c1f038630b 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 148 168 8.4E-10 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS21110 aaf6d119f0f98f8473dbf7c1f038630b 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 130 146 8.4E-10 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS21110 aaf6d119f0f98f8473dbf7c1f038630b 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 8.4E-10 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS21110 aaf6d119f0f98f8473dbf7c1f038630b 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 99 112 8.4E-10 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS21110 aaf6d119f0f98f8473dbf7c1f038630b 219 SUPERFAMILY SSF56784 1 215 3.45E-50 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS21110 aaf6d119f0f98f8473dbf7c1f038630b 219 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 77 183 5.8E-15 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS21110 aaf6d119f0f98f8473dbf7c1f038630b 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 182 5.5E-32 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS10825 607196f02cc32d51564e3edd9b160e12 267 Pfam PF01844 HNH endonuclease 218 251 9.3E-10 T 05-07-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 K08M4_RS10825 607196f02cc32d51564e3edd9b160e12 267 SMART SM00507 190 248 1.4E-7 T 05-07-2017 IPR003615 HNH nuclease K08M4_RS11945 7bd131dbe0bf5e554fe07ee2207c2a64 146 Pfam PF00571 CBS domain 79 127 5.3E-10 T 05-07-2017 IPR000644 CBS domain K08M4_RS11945 7bd131dbe0bf5e554fe07ee2207c2a64 146 Pfam PF00571 CBS domain 4 58 7.3E-13 T 05-07-2017 IPR000644 CBS domain K08M4_RS11945 7bd131dbe0bf5e554fe07ee2207c2a64 146 SUPERFAMILY SSF54631 1 132 4.3E-33 T 05-07-2017 K08M4_RS11945 7bd131dbe0bf5e554fe07ee2207c2a64 146 Gene3D G3DSA:3.10.580.10 2 140 2.3E-30 T 05-07-2017 K08M4_RS11945 7bd131dbe0bf5e554fe07ee2207c2a64 146 SMART SM00116 11 59 7.8E-8 T 05-07-2017 IPR000644 CBS domain K08M4_RS11945 7bd131dbe0bf5e554fe07ee2207c2a64 146 SMART SM00116 84 131 2.5E-6 T 05-07-2017 IPR000644 CBS domain K08M4_RS04065 1975df7ed08e6fa14b235a60020d3e82 262 SUPERFAMILY SSF117143 92 223 5.23E-35 T 05-07-2017 K08M4_RS04065 1975df7ed08e6fa14b235a60020d3e82 262 Pfam PF00460 Flagella basal body rod protein 5 35 8.8E-11 T 05-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 K08M4_RS04065 1975df7ed08e6fa14b235a60020d3e82 262 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 137 2.1E-40 T 05-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G K08M4_RS04065 1975df7ed08e6fa14b235a60020d3e82 262 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 147 244 1.9E-30 T 05-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G K08M4_RS04065 1975df7ed08e6fa14b235a60020d3e82 262 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 05-07-2017 IPR019776 Flagellar basal body rod protein, conserved site K08M4_RS04065 1975df7ed08e6fa14b235a60020d3e82 262 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 261 1.1E-115 T 05-07-2017 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 K08M4_RS04065 1975df7ed08e6fa14b235a60020d3e82 262 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 184 260 6.3E-24 T 05-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain K08M4_RS10655 d7ddecb88fe002a4427d33e48b1c154b 378 Gene3D G3DSA:3.20.20.140 55 346 7.2E-101 T 05-07-2017 K08M4_RS10655 d7ddecb88fe002a4427d33e48b1c154b 378 SUPERFAMILY SSF51338 1 53 2.31E-19 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS10655 d7ddecb88fe002a4427d33e48b1c154b 378 SUPERFAMILY SSF51556 54 347 1.7E-100 T 05-07-2017 IPR032466 Metal-dependent hydrolase K08M4_RS10655 d7ddecb88fe002a4427d33e48b1c154b 378 Pfam PF01979 Amidohydrolase family 51 374 9.9E-37 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 K08M4_RS10655 d7ddecb88fe002a4427d33e48b1c154b 378 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 1 374 5.2E-153 T 05-07-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 K08M4_RS10655 d7ddecb88fe002a4427d33e48b1c154b 378 Gene3D G3DSA:2.30.40.10 2 54 2.3E-10 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS10655 d7ddecb88fe002a4427d33e48b1c154b 378 Gene3D G3DSA:2.30.40.10 347 363 2.3E-10 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS10655 d7ddecb88fe002a4427d33e48b1c154b 378 PIRSF PIRSF038994 1 378 8.2E-123 T 05-07-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 K08M4_RS04130 52c5b8d6db300aefa7c89cb0c5abff18 136 Pfam PF02561 Flagellar protein FliS 6 122 2.5E-37 T 05-07-2017 IPR003713 Flagellar protein FliS GO:0044780 K08M4_RS04130 52c5b8d6db300aefa7c89cb0c5abff18 136 SUPERFAMILY SSF101116 6 127 6.93E-39 T 05-07-2017 IPR003713 Flagellar protein FliS GO:0044780 K08M4_RS04130 52c5b8d6db300aefa7c89cb0c5abff18 136 PIRSF PIRSF039090 1 132 1.3E-42 T 05-07-2017 IPR003713 Flagellar protein FliS GO:0044780 K08M4_RS04130 52c5b8d6db300aefa7c89cb0c5abff18 136 Gene3D G3DSA:1.20.120.340 6 127 2.9E-41 T 05-07-2017 IPR003713 Flagellar protein FliS GO:0044780 K08M4_RS04130 52c5b8d6db300aefa7c89cb0c5abff18 136 TIGRFAM TIGR00208 fliS: flagellar protein FliS 4 122 1.9E-23 T 05-07-2017 IPR003713 Flagellar protein FliS GO:0044780 K08M4_RS18335 ac4c2b2995af8dfdc8f22add4c7a7ca6 116 SUPERFAMILY SSF46894 42 115 3.4E-11 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS18335 ac4c2b2995af8dfdc8f22add4c7a7ca6 116 SMART SM00862 43 114 1.6E-7 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS18335 ac4c2b2995af8dfdc8f22add4c7a7ca6 116 Gene3D G3DSA:1.10.10.10 48 115 4.1E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS18335 ac4c2b2995af8dfdc8f22add4c7a7ca6 116 Pfam PF00486 Transcriptional regulatory protein, C terminal 48 114 1.1E-9 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS03595 8efe31ab3ab6d980d1b754c06ca24fa3 92 Gene3D G3DSA:3.30.70.1460 8 92 7.5E-36 T 05-07-2017 IPR027471 YbeD-like domain K08M4_RS03595 8efe31ab3ab6d980d1b754c06ca24fa3 92 Pfam PF04359 Protein of unknown function (DUF493) 12 92 9.1E-29 T 05-07-2017 IPR007454 Uncharacterised protein family UPF0250 K08M4_RS03595 8efe31ab3ab6d980d1b754c06ca24fa3 92 SUPERFAMILY SSF117991 7 92 3.14E-31 T 05-07-2017 IPR027471 YbeD-like domain K08M4_RS03595 8efe31ab3ab6d980d1b754c06ca24fa3 92 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 6 92 26.502 T 05-07-2017 IPR007454 Uncharacterised protein family UPF0250 K08M4_RS18825 17c1cb518af6da67caf3ffad7a99ed3e 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.1E-20 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS18825 17c1cb518af6da67caf3ffad7a99ed3e 301 Gene3D G3DSA:3.40.190.10 177 262 1.2E-15 T 05-07-2017 K08M4_RS18825 17c1cb518af6da67caf3ffad7a99ed3e 301 SUPERFAMILY SSF46785 3 111 1.58E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS18825 17c1cb518af6da67caf3ffad7a99ed3e 301 SUPERFAMILY SSF53850 90 286 1.33E-37 T 05-07-2017 K08M4_RS18825 17c1cb518af6da67caf3ffad7a99ed3e 301 Gene3D G3DSA:1.10.10.10 3 81 2.3E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS18825 17c1cb518af6da67caf3ffad7a99ed3e 301 Pfam PF03466 LysR substrate binding domain 89 285 7.8E-43 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS18825 17c1cb518af6da67caf3ffad7a99ed3e 301 Gene3D G3DSA:3.40.190.10 91 176 4.5E-17 T 05-07-2017 K08M4_RS18825 17c1cb518af6da67caf3ffad7a99ed3e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.5E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS18825 17c1cb518af6da67caf3ffad7a99ed3e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.5E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS18825 17c1cb518af6da67caf3ffad7a99ed3e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.5E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 171 1.5E-20 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 2 626 46.537 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 Pfam PF01751 Toprim domain 413 521 9.0E-12 T 05-07-2017 IPR006171 Toprim domain K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 Pfam PF00204 DNA gyrase B 218 384 1.9E-41 T 05-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 SUPERFAMILY SSF54211 217 382 6.83E-46 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 Gene3D G3DSA:3.30.230.10 216 390 4.6E-46 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR00418 DNA topoisomerase II family signature 109 123 6.3E-58 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR00418 DNA topoisomerase II family signature 479 495 6.3E-58 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR00418 DNA topoisomerase II family signature 497 514 6.3E-58 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR00418 DNA topoisomerase II family signature 414 428 6.3E-58 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR00418 DNA topoisomerase II family signature 560 576 6.3E-58 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR00418 DNA topoisomerase II family signature 66 79 6.3E-58 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR00418 DNA topoisomerase II family signature 266 279 6.3E-58 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR00418 DNA topoisomerase II family signature 517 529 6.3E-58 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR00418 DNA topoisomerase II family signature 31 46 6.3E-58 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 SMART SM00387 27 173 1.3E-21 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR01098 Topoisomerase IV subunit B signature 26 39 9.9E-118 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR01098 Topoisomerase IV subunit B signature 174 191 9.9E-118 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR01098 Topoisomerase IV subunit B signature 448 469 9.9E-118 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR01098 Topoisomerase IV subunit B signature 503 519 9.9E-118 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR01098 Topoisomerase IV subunit B signature 537 559 9.9E-118 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR01098 Topoisomerase IV subunit B signature 192 213 9.9E-118 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR01098 Topoisomerase IV subunit B signature 311 326 9.9E-118 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR01098 Topoisomerase IV subunit B signature 469 481 9.9E-118 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR01098 Topoisomerase IV subunit B signature 238 261 9.9E-118 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR01098 Topoisomerase IV subunit B signature 135 149 9.9E-118 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR01098 Topoisomerase IV subunit B signature 294 310 9.9E-118 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR01098 Topoisomerase IV subunit B signature 362 387 9.9E-118 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR01098 Topoisomerase IV subunit B signature 338 361 9.9E-118 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 PRINTS PR01098 Topoisomerase IV subunit B signature 149 164 9.9E-118 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 SMART SM00433 34 622 2.4E-212 T 05-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 SUPERFAMILY SSF56719 388 619 6.28E-79 T 05-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 SUPERFAMILY SSF55874 4 215 9.9E-66 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 556 618 3.8E-27 T 05-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 Gene3D G3DSA:3.30.565.10 5 215 2.2E-76 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 Gene3D G3DSA:3.40.50.670 398 609 4.8E-79 T 05-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 K08M4_RS12705 82bf587530da9ef48c940772dfce28eb 626 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 3 623 0.0 T 05-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 K08M4_RS03255 0a145faa8f15f3f1edad3a546ecaba2d 326 Gene3D G3DSA:3.40.50.1000 169 297 2.1E-35 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS03255 0a145faa8f15f3f1edad3a546ecaba2d 326 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 102 310 4.2E-85 T 05-07-2017 K08M4_RS03255 0a145faa8f15f3f1edad3a546ecaba2d 326 Pfam PF00702 haloacid dehalogenase-like hydrolase 107 279 1.7E-13 T 05-07-2017 K08M4_RS03255 0a145faa8f15f3f1edad3a546ecaba2d 326 SUPERFAMILY SSF56784 103 312 6.64E-49 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS03255 0a145faa8f15f3f1edad3a546ecaba2d 326 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 107 275 1.8E-24 T 05-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 K08M4_RS03255 0a145faa8f15f3f1edad3a546ecaba2d 326 Gene3D G3DSA:1.10.150.210 117 168 2.9E-28 T 05-07-2017 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 K08M4_RS04725 b6b7c784da103b0e613be3930af46304 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 1.2E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS04725 b6b7c784da103b0e613be3930af46304 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.2E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS04725 b6b7c784da103b0e613be3930af46304 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.8E-18 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS04725 b6b7c784da103b0e613be3930af46304 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.8E-18 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS04725 b6b7c784da103b0e613be3930af46304 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.8E-18 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS04725 b6b7c784da103b0e613be3930af46304 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.8E-18 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS04725 b6b7c784da103b0e613be3930af46304 228 SUPERFAMILY SSF51735 1 228 2.84E-77 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04725 b6b7c784da103b0e613be3930af46304 228 Pfam PF00106 short chain dehydrogenase 3 189 1.2E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS04725 b6b7c784da103b0e613be3930af46304 228 Gene3D G3DSA:3.40.50.720 1 228 1.5E-65 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13425 2ed4e31ae73a4cce7bbf014e2924cea6 440 Pfam PF01609 Transposase DDE domain 132 355 4.3E-20 T 05-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 K08M4_RS13425 2ed4e31ae73a4cce7bbf014e2924cea6 440 Pfam PF13006 Insertion element 4 transposase N-terminal 22 112 3.0E-21 T 05-07-2017 IPR024473 Transposase, IS4, N-terminal K08M4_RS13425 2ed4e31ae73a4cce7bbf014e2924cea6 440 SUPERFAMILY SSF53098 107 360 1.67E-22 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS19655 2ed4e31ae73a4cce7bbf014e2924cea6 440 Pfam PF01609 Transposase DDE domain 132 355 4.3E-20 T 05-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 K08M4_RS19655 2ed4e31ae73a4cce7bbf014e2924cea6 440 Pfam PF13006 Insertion element 4 transposase N-terminal 22 112 3.0E-21 T 05-07-2017 IPR024473 Transposase, IS4, N-terminal K08M4_RS19655 2ed4e31ae73a4cce7bbf014e2924cea6 440 SUPERFAMILY SSF53098 107 360 1.67E-22 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS16025 77510d75520846592cc27a185ebc7341 318 Gene3D G3DSA:3.40.50.300 17 182 2.3E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16025 77510d75520846592cc27a185ebc7341 318 PIRSF PIRSF002849 1 318 3.0E-128 T 05-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted K08M4_RS16025 77510d75520846592cc27a185ebc7341 318 SUPERFAMILY SSF52540 6 292 2.27E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16025 77510d75520846592cc27a185ebc7341 318 Gene3D G3DSA:1.10.8.300 200 313 2.9E-43 T 05-07-2017 K08M4_RS16025 77510d75520846592cc27a185ebc7341 318 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 36 166 6.2E-63 T 05-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 K08M4_RS05870 1796c04943febe1b0962490a712ca79d 245 Gene3D G3DSA:3.90.1070.10 90 155 9.1E-10 T 05-07-2017 K08M4_RS05870 1796c04943febe1b0962490a712ca79d 245 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 3 239 9.1E-56 T 05-07-2017 IPR006380 Sucrose-phosphatase, N-terminal K08M4_RS05870 1796c04943febe1b0962490a712ca79d 245 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 195 4.9E-22 T 05-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 K08M4_RS05870 1796c04943febe1b0962490a712ca79d 245 SUPERFAMILY SSF56784 1 236 7.75E-34 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS05870 1796c04943febe1b0962490a712ca79d 245 Gene3D G3DSA:3.40.50.1000 156 237 5.8E-30 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS05870 1796c04943febe1b0962490a712ca79d 245 Gene3D G3DSA:3.40.50.1000 1 80 5.8E-30 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS18495 96a72786e99ee4167848d91a1177ad03 93 Pfam PF10115 Transcriptional activator HlyU 2 92 3.7E-40 T 05-07-2017 IPR018772 Transcription activator HlyU K08M4_RS09015 3a367e04fcd9c99ba969f824ff38c801 512 Gene3D G3DSA:2.40.440.10 400 452 1.2E-11 T 05-07-2017 K08M4_RS09015 3a367e04fcd9c99ba969f824ff38c801 512 Gene3D G3DSA:2.40.440.10 285 333 1.2E-11 T 05-07-2017 K08M4_RS09015 3a367e04fcd9c99ba969f824ff38c801 512 SUPERFAMILY SSF141523 288 342 6.54E-19 T 05-07-2017 K08M4_RS09015 3a367e04fcd9c99ba969f824ff38c801 512 SUPERFAMILY SSF141523 398 454 6.54E-19 T 05-07-2017 K08M4_RS09015 3a367e04fcd9c99ba969f824ff38c801 512 Gene3D G3DSA:1.10.101.10 199 270 6.2E-13 T 05-07-2017 IPR002477 Peptidoglycan binding-like K08M4_RS09015 3a367e04fcd9c99ba969f824ff38c801 512 Pfam PF01471 Putative peptidoglycan binding domain 230 261 2.0E-7 T 05-07-2017 IPR002477 Peptidoglycan binding-like K08M4_RS09015 3a367e04fcd9c99ba969f824ff38c801 512 Pfam PF03734 L,D-transpeptidase catalytic domain 289 456 6.2E-31 T 05-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 K08M4_RS09015 3a367e04fcd9c99ba969f824ff38c801 512 SUPERFAMILY SSF47090 197 268 1.1E-9 T 05-07-2017 IPR002477 Peptidoglycan binding-like K08M4_RS10990 5446aaad90fb4d03505c230ff818b6e7 224 SUPERFAMILY SSF55166 22 176 2.28E-19 T 05-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 K08M4_RS10990 5446aaad90fb4d03505c230ff818b6e7 224 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 25 176 1.6E-36 T 05-07-2017 IPR003709 Peptidase M15B GO:0006508|GO:0008233 K08M4_RS14485 ef74136c17c2e4e9b4595a08f95ab478 398 SUPERFAMILY SSF51905 341 397 4.91E-57 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14485 ef74136c17c2e4e9b4595a08f95ab478 398 SUPERFAMILY SSF51905 5 194 4.91E-57 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14485 ef74136c17c2e4e9b4595a08f95ab478 398 Gene3D G3DSA:2.40.30.10 195 274 4.1E-27 T 05-07-2017 K08M4_RS14485 ef74136c17c2e4e9b4595a08f95ab478 398 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 366 373 8.9E-9 T 05-07-2017 K08M4_RS14485 ef74136c17c2e4e9b4595a08f95ab478 398 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 170 8.9E-9 T 05-07-2017 K08M4_RS14485 ef74136c17c2e4e9b4595a08f95ab478 398 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 8.9E-9 T 05-07-2017 K08M4_RS14485 ef74136c17c2e4e9b4595a08f95ab478 398 SUPERFAMILY SSF160996 196 342 5.23E-42 T 05-07-2017 K08M4_RS14485 ef74136c17c2e4e9b4595a08f95ab478 398 Pfam PF03486 HI0933-like protein 7 397 1.5E-147 T 05-07-2017 K08M4_RS14485 ef74136c17c2e4e9b4595a08f95ab478 398 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 8 396 3.5E-126 T 05-07-2017 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like K08M4_RS14485 ef74136c17c2e4e9b4595a08f95ab478 398 Gene3D G3DSA:3.50.50.60 344 397 2.1E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14485 ef74136c17c2e4e9b4595a08f95ab478 398 Gene3D G3DSA:3.50.50.60 6 193 2.1E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14485 ef74136c17c2e4e9b4595a08f95ab478 398 Gene3D G3DSA:1.10.8.260 275 326 9.6E-20 T 05-07-2017 IPR023166 HI0933 insert-like domain K08M4_RS14485 ef74136c17c2e4e9b4595a08f95ab478 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 351 373 1.9E-6 T 05-07-2017 K08M4_RS14485 ef74136c17c2e4e9b4595a08f95ab478 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 1.9E-6 T 05-07-2017 K08M4_RS14485 ef74136c17c2e4e9b4595a08f95ab478 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.9E-6 T 05-07-2017 K08M4_RS20950 a64fead010d6dd450d327116b837021a 140 Gene3D G3DSA:3.30.300.20 44 136 1.6E-36 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta K08M4_RS20950 a64fead010d6dd450d327116b837021a 140 Gene3D G3DSA:2.20.25.10 1 43 2.7E-20 T 05-07-2017 K08M4_RS20950 a64fead010d6dd450d327116b837021a 140 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 135 5.2E-54 T 05-07-2017 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 K08M4_RS20950 a64fead010d6dd450d327116b837021a 140 SUPERFAMILY SSF82784 1 135 1.09E-42 T 05-07-2017 IPR003718 OsmC/Ohr family K08M4_RS20950 a64fead010d6dd450d327116b837021a 140 Pfam PF02566 OsmC-like protein 38 133 1.1E-18 T 05-07-2017 IPR003718 OsmC/Ohr family K08M4_RS12400 def2156ec8a661e157b430f94575df0a 125 SUPERFAMILY SSF51998 64 124 2.52E-23 T 05-07-2017 K08M4_RS12400 def2156ec8a661e157b430f94575df0a 125 ProSitePatterns PS00850 Glycine radical domain signature. 95 103 - T 05-07-2017 IPR019777 Formate C-acetyltransferase glycine radical, conserved site K08M4_RS12400 def2156ec8a661e157b430f94575df0a 125 Pfam PF01228 Glycine radical 16 106 5.9E-23 T 05-07-2017 IPR001150 Glycine radical domain GO:0003824|GO:0008152 K08M4_RS12400 def2156ec8a661e157b430f94575df0a 125 Hamap MF_00806 Autonomous glycyl radical cofactor [grcA]. 1 125 41.822 T 05-07-2017 IPR011140 Autonomous glycyl radical cofactor GrcA K08M4_RS12400 def2156ec8a661e157b430f94575df0a 125 TIGRFAM TIGR04365 spare_glycyl: autonomous glycyl radical cofactor GrcA 2 125 6.5E-68 T 05-07-2017 IPR011140 Autonomous glycyl radical cofactor GrcA K08M4_RS12400 def2156ec8a661e157b430f94575df0a 125 PIRSF PIRSF000378 2 125 1.4E-53 T 05-07-2017 IPR011140 Autonomous glycyl radical cofactor GrcA K08M4_RS12400 def2156ec8a661e157b430f94575df0a 125 Gene3D G3DSA:3.20.70.20 34 124 2.4E-33 T 05-07-2017 K08M4_RS15835 e8b42fbb07aed5b2e873d9650ac80afa 411 SUPERFAMILY SSF81901 63 280 1.66E-28 T 05-07-2017 K08M4_RS15835 e8b42fbb07aed5b2e873d9650ac80afa 411 Pfam PF08238 Sel1 repeat 209 238 2.5E-6 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS15835 e8b42fbb07aed5b2e873d9650ac80afa 411 Pfam PF08238 Sel1 repeat 134 167 160.0 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS15835 e8b42fbb07aed5b2e873d9650ac80afa 411 Pfam PF08238 Sel1 repeat 169 203 0.0024 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS15835 e8b42fbb07aed5b2e873d9650ac80afa 411 Pfam PF08238 Sel1 repeat 78 94 0.29 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS15835 e8b42fbb07aed5b2e873d9650ac80afa 411 SMART SM00671 204 239 6.1E-4 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS15835 e8b42fbb07aed5b2e873d9650ac80afa 411 SMART SM00671 59 94 130.0 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS15835 e8b42fbb07aed5b2e873d9650ac80afa 411 SMART SM00671 132 167 0.27 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS15835 e8b42fbb07aed5b2e873d9650ac80afa 411 SMART SM00671 168 203 2.8 T 05-07-2017 IPR006597 Sel1-like repeat K08M4_RS15835 e8b42fbb07aed5b2e873d9650ac80afa 411 Gene3D G3DSA:1.25.40.10 60 283 6.3E-33 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS14785 d077c9e8ea162e852135293c66e1e307 363 SMART SM00257 37 85 8.9E-4 T 05-07-2017 IPR018392 LysM domain K08M4_RS14785 d077c9e8ea162e852135293c66e1e307 363 Gene3D G3DSA:3.10.350.10 37 84 4.5E-6 T 05-07-2017 IPR018392 LysM domain K08M4_RS14785 d077c9e8ea162e852135293c66e1e307 363 SUPERFAMILY SSF54106 37 84 2.49E-6 T 05-07-2017 IPR018392 LysM domain K08M4_RS14785 d077c9e8ea162e852135293c66e1e307 363 Pfam PF01476 LysM domain 38 83 3.6E-11 T 05-07-2017 IPR018392 LysM domain K08M4_RS11160 bd39462bf1674fe7a434f3206bc3d401 398 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 18 392 40.755 T 05-07-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 K08M4_RS11160 bd39462bf1674fe7a434f3206bc3d401 398 SUPERFAMILY SSF53756 20 311 3.01E-27 T 05-07-2017 K08M4_RS11160 bd39462bf1674fe7a434f3206bc3d401 398 Pfam PF02684 Lipid-A-disaccharide synthetase 23 386 4.7E-125 T 05-07-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 K08M4_RS11160 bd39462bf1674fe7a434f3206bc3d401 398 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 20 390 4.7E-134 T 05-07-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 K08M4_RS11160 bd39462bf1674fe7a434f3206bc3d401 398 Gene3D G3DSA:3.40.50.2000 174 303 2.2E-5 T 05-07-2017 K08M4_RS08300 0a6572f0a9d6c3c85ba8a42804d8bcf3 838 Gene3D G3DSA:1.20.1640.10 627 816 3.4E-33 T 05-07-2017 K08M4_RS08300 0a6572f0a9d6c3c85ba8a42804d8bcf3 838 Gene3D G3DSA:1.20.1640.10 222 423 1.9E-35 T 05-07-2017 K08M4_RS08300 0a6572f0a9d6c3c85ba8a42804d8bcf3 838 SUPERFAMILY SSF82866 629 807 1.27E-32 T 05-07-2017 K08M4_RS08300 0a6572f0a9d6c3c85ba8a42804d8bcf3 838 SUPERFAMILY SSF82866 200 420 8.76E-33 T 05-07-2017 K08M4_RS08300 0a6572f0a9d6c3c85ba8a42804d8bcf3 838 Pfam PF03176 MMPL family 99 426 4.9E-21 T 05-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 K08M4_RS08300 0a6572f0a9d6c3c85ba8a42804d8bcf3 838 Pfam PF03176 MMPL family 629 808 2.4E-15 T 05-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 K08M4_RS08300 0a6572f0a9d6c3c85ba8a42804d8bcf3 838 PRINTS PR00702 Acriflavin resistance protein family signature 288 312 3.2E-6 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS08300 0a6572f0a9d6c3c85ba8a42804d8bcf3 838 PRINTS PR00702 Acriflavin resistance protein family signature 704 728 3.2E-6 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS08300 0a6572f0a9d6c3c85ba8a42804d8bcf3 838 PRINTS PR00702 Acriflavin resistance protein family signature 779 802 3.2E-6 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS08300 0a6572f0a9d6c3c85ba8a42804d8bcf3 838 PRINTS PR00702 Acriflavin resistance protein family signature 649 672 3.2E-6 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS05945 d55459d26bb798adfabb5387001a736d 407 Gene3D G3DSA:3.30.70.270 236 393 1.5E-43 T 05-07-2017 K08M4_RS05945 d55459d26bb798adfabb5387001a736d 407 SUPERFAMILY SSF55785 99 221 6.47E-6 T 05-07-2017 IPR000014 PAS domain K08M4_RS05945 d55459d26bb798adfabb5387001a736d 407 SUPERFAMILY SSF55073 239 393 9.42E-36 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS05945 d55459d26bb798adfabb5387001a736d 407 SMART SM00267 223 395 4.0E-46 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS05945 d55459d26bb798adfabb5387001a736d 407 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 232 392 2.9E-37 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS05945 d55459d26bb798adfabb5387001a736d 407 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 105 230 9.5E-8 T 05-07-2017 IPR000014 PAS domain K08M4_RS05945 d55459d26bb798adfabb5387001a736d 407 SUPERFAMILY SSF55785 2 95 9.52E-8 T 05-07-2017 IPR000014 PAS domain K08M4_RS05945 d55459d26bb798adfabb5387001a736d 407 Gene3D G3DSA:3.30.450.20 2 92 5.2E-6 T 05-07-2017 K08M4_RS05945 d55459d26bb798adfabb5387001a736d 407 Pfam PF00990 Diguanylate cyclase, GGDEF domain 234 390 8.0E-36 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS05945 d55459d26bb798adfabb5387001a736d 407 Gene3D G3DSA:3.30.450.20 99 221 1.6E-7 T 05-07-2017 K08M4_RS04580 2e6de70cd8d6d06faf85b56509175d77 504 SUPERFAMILY SSF56235 2 256 1.12E-70 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS04580 2e6de70cd8d6d06faf85b56509175d77 504 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 463 5.8E-164 T 05-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 K08M4_RS04580 2e6de70cd8d6d06faf85b56509175d77 504 PIRSF PIRSF000485 1 480 2.6E-167 T 05-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 K08M4_RS04580 2e6de70cd8d6d06faf85b56509175d77 504 Pfam PF13522 Glutamine amidotransferase domain 64 207 2.6E-17 T 05-07-2017 K08M4_RS04580 2e6de70cd8d6d06faf85b56509175d77 504 SUPERFAMILY SSF53271 249 482 2.1E-68 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS04580 2e6de70cd8d6d06faf85b56509175d77 504 Gene3D G3DSA:3.40.50.2020 270 442 7.2E-45 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS04580 2e6de70cd8d6d06faf85b56509175d77 504 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 465 44.382 T 05-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 K08M4_RS04580 2e6de70cd8d6d06faf85b56509175d77 504 Gene3D G3DSA:3.60.20.10 2 257 3.9E-64 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS12185 bcd41d0028115195500e37a7a0b9a8f1 357 PIRSF PIRSF001361 1 353 1.8E-162 T 05-07-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 K08M4_RS12185 bcd41d0028115195500e37a7a0b9a8f1 357 SUPERFAMILY SSF51569 8 344 1.74E-137 T 05-07-2017 K08M4_RS12185 bcd41d0028115195500e37a7a0b9a8f1 357 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 9 346 4.4E-162 T 05-07-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 K08M4_RS12185 bcd41d0028115195500e37a7a0b9a8f1 357 Pfam PF00793 DAHP synthetase I family 42 340 8.8E-105 T 05-07-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 K08M4_RS12185 bcd41d0028115195500e37a7a0b9a8f1 357 Gene3D G3DSA:3.20.20.70 11 348 6.9E-154 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS00870 e3693ff58a8eaffa19c30a90009188cf 383 Pfam PF01595 Domain of unknown function DUF21 10 177 2.6E-29 T 05-07-2017 IPR002550 Domain of unknown function DUF21 K08M4_RS00870 e3693ff58a8eaffa19c30a90009188cf 383 Gene3D G3DSA:3.10.580.10 181 321 1.1E-16 T 05-07-2017 K08M4_RS00870 e3693ff58a8eaffa19c30a90009188cf 383 Pfam PF00571 CBS domain 260 313 1.1E-6 T 05-07-2017 IPR000644 CBS domain K08M4_RS00870 e3693ff58a8eaffa19c30a90009188cf 383 SUPERFAMILY SSF54631 181 315 1.65E-25 T 05-07-2017 K08M4_RS15430 461b198eae1ee6355db446fc257de641 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 2.5E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS15430 461b198eae1ee6355db446fc257de641 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 2.5E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS15430 461b198eae1ee6355db446fc257de641 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 2.5E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS15430 461b198eae1ee6355db446fc257de641 300 Gene3D G3DSA:1.10.10.10 3 87 6.3E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15430 461b198eae1ee6355db446fc257de641 300 SUPERFAMILY SSF53850 126 297 3.44E-32 T 05-07-2017 K08M4_RS15430 461b198eae1ee6355db446fc257de641 300 Gene3D G3DSA:3.40.190.10 273 299 2.3E-13 T 05-07-2017 K08M4_RS15430 461b198eae1ee6355db446fc257de641 300 Gene3D G3DSA:3.40.190.10 126 172 2.3E-13 T 05-07-2017 K08M4_RS15430 461b198eae1ee6355db446fc257de641 300 Pfam PF03466 LysR substrate binding domain 126 297 4.8E-17 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS15430 461b198eae1ee6355db446fc257de641 300 Gene3D G3DSA:3.40.190.10 173 268 5.0E-18 T 05-07-2017 K08M4_RS15430 461b198eae1ee6355db446fc257de641 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 1.0E-15 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS15430 461b198eae1ee6355db446fc257de641 300 SUPERFAMILY SSF46785 6 88 2.61E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16905 152f7c33d09af472933d204f67a276bc 369 Gene3D G3DSA:3.40.50.300 3 239 3.0E-81 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16905 152f7c33d09af472933d204f67a276bc 369 SMART SM00382 31 214 9.3E-20 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS16905 152f7c33d09af472933d204f67a276bc 369 Pfam PF00005 ABC transporter 22 164 9.8E-34 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS16905 152f7c33d09af472933d204f67a276bc 369 TIGRFAM TIGR03265 PhnT2: putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein 4 357 8.9E-157 T 05-07-2017 IPR017666 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT2 GO:0005524 K08M4_RS16905 152f7c33d09af472933d204f67a276bc 369 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS16905 152f7c33d09af472933d204f67a276bc 369 SUPERFAMILY SSF50331 239 360 9.07E-10 T 05-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal K08M4_RS16905 152f7c33d09af472933d204f67a276bc 369 SUPERFAMILY SSF52540 7 245 3.99E-86 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17775 7567fa5d37cbdfba258e1dd77e2a14e2 243 Pfam PF00072 Response regulator receiver domain 12 121 7.8E-22 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS17775 7567fa5d37cbdfba258e1dd77e2a14e2 243 SMART SM00448 10 121 1.0E-33 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS17775 7567fa5d37cbdfba258e1dd77e2a14e2 243 Gene3D G3DSA:3.40.50.2300 7 129 4.6E-37 T 05-07-2017 K08M4_RS17775 7567fa5d37cbdfba258e1dd77e2a14e2 243 SMART SM00862 163 239 3.6E-20 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS17775 7567fa5d37cbdfba258e1dd77e2a14e2 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 239 2.9E-23 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS17775 7567fa5d37cbdfba258e1dd77e2a14e2 243 SUPERFAMILY SSF46894 141 240 3.12E-28 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS17775 7567fa5d37cbdfba258e1dd77e2a14e2 243 SUPERFAMILY SSF52172 8 137 1.17E-36 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS17775 7567fa5d37cbdfba258e1dd77e2a14e2 243 Gene3D G3DSA:1.10.10.10 141 242 1.8E-32 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19455 6a45b2b4acbb59961b0b2a02995ea654 292 Gene3D G3DSA:3.40.50.2300 25 142 9.6E-45 T 05-07-2017 K08M4_RS19455 6a45b2b4acbb59961b0b2a02995ea654 292 Pfam PF13407 Periplasmic binding protein domain 28 277 2.1E-59 T 05-07-2017 IPR025997 Periplasmic binding protein K08M4_RS19455 6a45b2b4acbb59961b0b2a02995ea654 292 Gene3D G3DSA:3.40.50.2300 143 291 4.3E-52 T 05-07-2017 K08M4_RS19455 6a45b2b4acbb59961b0b2a02995ea654 292 SUPERFAMILY SSF53822 8 290 1.8E-83 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS04060 c8f1db3e55bc98549eb6deb184ad7499 249 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 6 226 2.3E-53 T 05-07-2017 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 K08M4_RS04060 c8f1db3e55bc98549eb6deb184ad7499 249 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 121 8.0E-34 T 05-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G K08M4_RS04060 c8f1db3e55bc98549eb6deb184ad7499 249 SUPERFAMILY SSF117143 77 207 2.48E-17 T 05-07-2017 K08M4_RS04060 c8f1db3e55bc98549eb6deb184ad7499 249 Pfam PF00460 Flagella basal body rod protein 8 35 1.7E-5 T 05-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 K08M4_RS04060 c8f1db3e55bc98549eb6deb184ad7499 249 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 172 242 3.3E-22 T 05-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain K08M4_RS06435 4da976fed2bd35a3c0c602f369b9fe88 271 SUPERFAMILY SSF51197 2 270 2.7E-84 T 05-07-2017 K08M4_RS06435 4da976fed2bd35a3c0c602f369b9fe88 271 Gene3D G3DSA:3.60.130.10 2 270 1.1E-84 T 05-07-2017 K08M4_RS06435 4da976fed2bd35a3c0c602f369b9fe88 271 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 4 269 2.3E-59 T 05-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 K08M4_RS14925 84b7b9df8340d2b8fead816e6e77db90 177 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 175 6.1E-50 T 05-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 K08M4_RS14925 84b7b9df8340d2b8fead816e6e77db90 177 PRINTS PR00125 ATP synthase delta subunit signature 150 168 6.4E-25 T 05-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 K08M4_RS14925 84b7b9df8340d2b8fead816e6e77db90 177 PRINTS PR00125 ATP synthase delta subunit signature 7 26 6.4E-25 T 05-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 K08M4_RS14925 84b7b9df8340d2b8fead816e6e77db90 177 PRINTS PR00125 ATP synthase delta subunit signature 85 99 6.4E-25 T 05-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 K08M4_RS14925 84b7b9df8340d2b8fead816e6e77db90 177 PRINTS PR00125 ATP synthase delta subunit signature 74 85 6.4E-25 T 05-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 K08M4_RS14925 84b7b9df8340d2b8fead816e6e77db90 177 PRINTS PR00125 ATP synthase delta subunit signature 135 150 6.4E-25 T 05-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 K08M4_RS14925 84b7b9df8340d2b8fead816e6e77db90 177 SUPERFAMILY SSF47928 3 105 2.35E-28 T 05-07-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 K08M4_RS14925 84b7b9df8340d2b8fead816e6e77db90 177 Gene3D G3DSA:1.10.520.20 3 105 5.2E-34 T 05-07-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 K08M4_RS14925 84b7b9df8340d2b8fead816e6e77db90 177 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 175 6.4E-60 T 05-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 K08M4_RS14925 84b7b9df8340d2b8fead816e6e77db90 177 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 137 156 - T 05-07-2017 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210 K08M4_RS14925 84b7b9df8340d2b8fead816e6e77db90 177 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 177 18.149 T 05-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 K08M4_RS13825 dc64601093d0b6d7a7d7fe1729371c5f 685 SUPERFAMILY SSF52540 398 582 1.66E-22 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13825 dc64601093d0b6d7a7d7fe1729371c5f 685 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 401 581 1.9E-32 T 05-07-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 K08M4_RS13825 dc64601093d0b6d7a7d7fe1729371c5f 685 Gene3D G3DSA:3.40.50.300 397 586 3.2E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13825 dc64601093d0b6d7a7d7fe1729371c5f 685 ProSitePatterns PS00567 Phosphoribulokinase signature. 532 545 - T 05-07-2017 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 K08M4_RS13825 dc64601093d0b6d7a7d7fe1729371c5f 685 PRINTS PR00478 Phosphoribulokinase family signature 497 515 5.3E-17 T 05-07-2017 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 K08M4_RS13825 dc64601093d0b6d7a7d7fe1729371c5f 685 PRINTS PR00478 Phosphoribulokinase family signature 532 549 5.3E-17 T 05-07-2017 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 K08M4_RS13825 dc64601093d0b6d7a7d7fe1729371c5f 685 PRINTS PR00478 Phosphoribulokinase family signature 406 423 5.3E-17 T 05-07-2017 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 K08M4_RS13825 dc64601093d0b6d7a7d7fe1729371c5f 685 PRINTS PR00478 Phosphoribulokinase family signature 550 573 5.3E-17 T 05-07-2017 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 K08M4_RS06140 590fe747ce8a3915cd076692e71813e9 524 SUPERFAMILY SSF52540 354 513 1.23E-30 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06140 590fe747ce8a3915cd076692e71813e9 524 Gene3D G3DSA:3.40.50.300 340 514 2.7E-28 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06140 590fe747ce8a3915cd076692e71813e9 524 Gene3D G3DSA:3.40.50.300 3 244 5.4E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06140 590fe747ce8a3915cd076692e71813e9 524 SMART SM00382 28 215 1.6E-5 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS06140 590fe747ce8a3915cd076692e71813e9 524 SMART SM00382 361 519 1.5E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS06140 590fe747ce8a3915cd076692e71813e9 524 Gene3D G3DSA:3.40.50.300 245 271 3.2E-4 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06140 590fe747ce8a3915cd076692e71813e9 524 Pfam PF00005 ABC transporter 355 481 1.9E-18 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS06140 590fe747ce8a3915cd076692e71813e9 524 Pfam PF00005 ABC transporter 21 170 7.1E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS06140 590fe747ce8a3915cd076692e71813e9 524 SUPERFAMILY SSF52540 17 221 2.31E-34 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06140 590fe747ce8a3915cd076692e71813e9 524 ProSitePatterns PS00211 ABC transporters family signature. 452 466 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS06140 590fe747ce8a3915cd076692e71813e9 524 Pfam PF12848 ABC transporter 209 269 5.5E-5 T 05-07-2017 IPR032781 ABC-transporter extension domain K08M4_RS02635 f8cb5ceae240372441d350c822227303 65 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 57 7.8E-30 T 05-07-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 K08M4_RS02635 f8cb5ceae240372441d350c822227303 65 SUPERFAMILY SSF117130 1 54 6.93E-21 T 05-07-2017 K08M4_RS02635 f8cb5ceae240372441d350c822227303 65 Pfam PF02599 Global regulator protein family 1 52 2.1E-26 T 05-07-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 K08M4_RS02635 f8cb5ceae240372441d350c822227303 65 Hamap MF_00167 Carbon storage regulator [csrA]. 1 62 20.37 T 05-07-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 K08M4_RS02635 f8cb5ceae240372441d350c822227303 65 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 5.0E-20 T 05-07-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 K08M4_RS01200 47bfb237287c548200f1c855d27f060b 334 Gene3D G3DSA:3.30.360.10 163 308 2.6E-50 T 05-07-2017 K08M4_RS01200 47bfb237287c548200f1c855d27f060b 334 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 149 165 - T 05-07-2017 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 K08M4_RS01200 47bfb237287c548200f1c855d27f060b 334 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 334 36.672 T 05-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 K08M4_RS01200 47bfb237287c548200f1c855d27f060b 334 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 146 5.1E-31 T 05-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 K08M4_RS01200 47bfb237287c548200f1c855d27f060b 334 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 333 2.2E-118 T 05-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 K08M4_RS01200 47bfb237287c548200f1c855d27f060b 334 SUPERFAMILY SSF51735 1 174 1.63E-41 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS01200 47bfb237287c548200f1c855d27f060b 334 Gene3D G3DSA:3.40.50.720 1 162 4.2E-56 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS01200 47bfb237287c548200f1c855d27f060b 334 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 163 311 1.0E-12 T 05-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 K08M4_RS01200 47bfb237287c548200f1c855d27f060b 334 SUPERFAMILY SSF55347 154 308 1.15E-49 T 05-07-2017 K08M4_RS01200 47bfb237287c548200f1c855d27f060b 334 SMART SM00859 3 146 7.5E-46 T 05-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 K08M4_RS07265 9f12b0fb4caedd33be1c619d50ad3ef2 134 SUPERFAMILY SSF159888 8 125 4.58E-11 T 05-07-2017 K08M4_RS07265 9f12b0fb4caedd33be1c619d50ad3ef2 134 Pfam PF08818 Domain of unknown function (DU1801) 19 120 1.8E-10 T 05-07-2017 IPR014922 Domain of unknown function DUF1801 K08M4_RS05280 75a0458c68be088723d46602bbd723ff 246 Gene3D G3DSA:1.10.3720.10 8 78 8.5E-39 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS05280 75a0458c68be088723d46602bbd723ff 246 Gene3D G3DSA:1.10.3720.10 110 241 8.5E-39 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS05280 75a0458c68be088723d46602bbd723ff 246 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 73 1.1E-15 T 05-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 K08M4_RS05280 75a0458c68be088723d46602bbd723ff 246 SUPERFAMILY SSF161098 110 233 1.7E-38 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS05280 75a0458c68be088723d46602bbd723ff 246 SUPERFAMILY SSF161098 11 78 1.7E-38 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS05280 75a0458c68be088723d46602bbd723ff 246 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 241 4.4E-20 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS13450 7a84317d2f5b3a2f5a9293407835e2d7 464 Pfam PF03796 DnaB-like helicase C terminal domain 199 455 3.6E-114 T 05-07-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 K08M4_RS13450 7a84317d2f5b3a2f5a9293407835e2d7 464 Pfam PF00772 DnaB-like helicase N terminal domain 20 120 3.3E-35 T 05-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 K08M4_RS13450 7a84317d2f5b3a2f5a9293407835e2d7 464 Gene3D G3DSA:3.40.50.300 194 457 3.7E-105 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13450 7a84317d2f5b3a2f5a9293407835e2d7 464 SUPERFAMILY SSF52540 197 268 2.5E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13450 7a84317d2f5b3a2f5a9293407835e2d7 464 SUPERFAMILY SSF52540 295 449 2.5E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13450 7a84317d2f5b3a2f5a9293407835e2d7 464 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 20 457 2.9E-174 T 05-07-2017 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 K08M4_RS13450 7a84317d2f5b3a2f5a9293407835e2d7 464 Gene3D G3DSA:1.10.860.10 20 121 4.4E-38 T 05-07-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal K08M4_RS13450 7a84317d2f5b3a2f5a9293407835e2d7 464 SUPERFAMILY SSF48024 18 129 3.14E-36 T 05-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 K08M4_RS12890 29ad943930a25aefd25e7471a2b249fc 319 Gene3D G3DSA:3.40.190.10 189 281 1.6E-14 T 05-07-2017 K08M4_RS12890 29ad943930a25aefd25e7471a2b249fc 319 SUPERFAMILY SSF53850 106 309 3.26E-39 T 05-07-2017 K08M4_RS12890 29ad943930a25aefd25e7471a2b249fc 319 Pfam PF03466 LysR substrate binding domain 117 308 5.7E-20 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS12890 29ad943930a25aefd25e7471a2b249fc 319 Gene3D G3DSA:1.10.10.10 17 101 7.8E-34 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS12890 29ad943930a25aefd25e7471a2b249fc 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 25 84 1.2E-18 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS12890 29ad943930a25aefd25e7471a2b249fc 319 SUPERFAMILY SSF46785 22 99 3.73E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS12890 29ad943930a25aefd25e7471a2b249fc 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 61 1.4E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS12890 29ad943930a25aefd25e7471a2b249fc 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 61 72 1.4E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS12890 29ad943930a25aefd25e7471a2b249fc 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.4E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS12890 29ad943930a25aefd25e7471a2b249fc 319 Gene3D G3DSA:3.40.190.10 106 188 7.9E-24 T 05-07-2017 K08M4_RS12890 29ad943930a25aefd25e7471a2b249fc 319 Gene3D G3DSA:3.40.190.10 287 314 7.9E-24 T 05-07-2017 K08M4_RS10215 d4b7fa09af09ed2da38cbd6b6dab0ca6 286 Gene3D G3DSA:3.10.129.10 125 284 2.8E-59 T 05-07-2017 IPR029069 HotDog domain K08M4_RS10215 d4b7fa09af09ed2da38cbd6b6dab0ca6 286 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 12 283 3.5E-95 T 05-07-2017 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-75105 K08M4_RS10215 d4b7fa09af09ed2da38cbd6b6dab0ca6 286 Gene3D G3DSA:3.10.129.10 4 116 1.9E-46 T 05-07-2017 IPR029069 HotDog domain K08M4_RS10215 d4b7fa09af09ed2da38cbd6b6dab0ca6 286 SUPERFAMILY SSF54637 5 114 3.13E-39 T 05-07-2017 IPR029069 HotDog domain K08M4_RS10215 d4b7fa09af09ed2da38cbd6b6dab0ca6 286 Pfam PF13622 Thioesterase-like superfamily 33 282 7.5E-61 T 05-07-2017 K08M4_RS10215 d4b7fa09af09ed2da38cbd6b6dab0ca6 286 SUPERFAMILY SSF54637 116 283 2.36E-59 T 05-07-2017 IPR029069 HotDog domain K08M4_RS18360 1c1078a2352221c04b43492a7cd12bb0 542 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 05-07-2017 IPR020845 AMP-binding, conserved site K08M4_RS18360 1c1078a2352221c04b43492a7cd12bb0 542 Pfam PF00501 AMP-binding enzyme 9 441 1.7E-106 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 K08M4_RS18360 1c1078a2352221c04b43492a7cd12bb0 542 Gene3D G3DSA:3.40.50.980 170 193 2.9E-33 T 05-07-2017 K08M4_RS18360 1c1078a2352221c04b43492a7cd12bb0 542 Gene3D G3DSA:3.40.50.980 8 115 2.9E-33 T 05-07-2017 K08M4_RS18360 1c1078a2352221c04b43492a7cd12bb0 542 Gene3D G3DSA:2.30.38.10 362 432 1.4E-25 T 05-07-2017 K08M4_RS18360 1c1078a2352221c04b43492a7cd12bb0 542 Gene3D G3DSA:3.30.300.30 436 532 3.2E-31 T 05-07-2017 K08M4_RS18360 1c1078a2352221c04b43492a7cd12bb0 542 SUPERFAMILY SSF56801 8 533 1.03E-149 T 05-07-2017 K08M4_RS18360 1c1078a2352221c04b43492a7cd12bb0 542 Pfam PF13193 AMP-binding enzyme C-terminal domain 450 525 1.9E-18 T 05-07-2017 IPR025110 AMP-binding enzyme C-terminal domain K08M4_RS18360 1c1078a2352221c04b43492a7cd12bb0 542 Gene3D G3DSA:3.40.50.980 194 361 5.5E-44 T 05-07-2017 K08M4_RS11260 4220d1afbcef54b571d513f7b55ff84e 346 Pfam PF12069 Protein of unknown function (DUF3549) 3 340 1.1E-133 T 05-07-2017 IPR021936 Protein of unknown function DUF3549 K08M4_RS13900 d9626f4bb9a81f3d9ed1700870db7e2c 391 Gene3D G3DSA:2.70.70.10 245 389 3.3E-35 T 05-07-2017 K08M4_RS13900 d9626f4bb9a81f3d9ed1700870db7e2c 391 Pfam PF01551 Peptidase family M23 292 385 1.5E-25 T 05-07-2017 IPR016047 Peptidase M23 K08M4_RS13900 d9626f4bb9a81f3d9ed1700870db7e2c 391 SUPERFAMILY SSF51261 157 389 1.62E-46 T 05-07-2017 IPR011055 Duplicated hybrid motif K08M4_RS05135 eb2159bb64bb3834d4006b0c2bc595d3 292 Gene3D G3DSA:3.20.10.10 149 285 5.4E-40 T 05-07-2017 K08M4_RS05135 eb2159bb64bb3834d4006b0c2bc595d3 292 ProSitePatterns PS00770 Aminotransferases class-IV signature. 198 227 - T 05-07-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 K08M4_RS05135 eb2159bb64bb3834d4006b0c2bc595d3 292 TIGRFAM TIGR03461 pabC_Proteo: aminodeoxychorismate lyase 98 287 1.3E-76 T 05-07-2017 IPR017824 Aminodeoxychorismate lyase, class IV GO:0008696|GO:0030170|GO:0046656 KEGG: 00790+4.1.3.38|MetaCyc: PWY-6543 K08M4_RS05135 eb2159bb64bb3834d4006b0c2bc595d3 292 Pfam PF01063 Amino-transferase class IV 24 272 1.2E-36 T 05-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 K08M4_RS05135 eb2159bb64bb3834d4006b0c2bc595d3 292 Gene3D G3DSA:3.30.470.10 1 132 2.9E-32 T 05-07-2017 K08M4_RS05135 eb2159bb64bb3834d4006b0c2bc595d3 292 SUPERFAMILY SSF56752 94 284 5.62E-59 T 05-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 K08M4_RS05135 eb2159bb64bb3834d4006b0c2bc595d3 292 SUPERFAMILY SSF56752 1 67 5.62E-59 T 05-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 K08M4_RS05305 ae4be78d23462fd763d07cb11f2d6524 401 Gene3D G3DSA:1.20.1250.20 208 392 7.8E-9 T 05-07-2017 K08M4_RS05305 ae4be78d23462fd763d07cb11f2d6524 401 Gene3D G3DSA:1.20.1250.20 11 194 6.9E-31 T 05-07-2017 K08M4_RS05305 ae4be78d23462fd763d07cb11f2d6524 401 SUPERFAMILY SSF103473 9 389 2.35E-58 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS05305 ae4be78d23462fd763d07cb11f2d6524 401 Pfam PF07690 Major Facilitator Superfamily 15 354 4.7E-44 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS05305 ae4be78d23462fd763d07cb11f2d6524 401 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 9 384 1.2E-61 T 05-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 K08M4_RS08765 18aa7a739a2dc1d1e76b79ff6ee12429 448 SUPERFAMILY SSF47384 222 286 6.08E-6 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS08765 18aa7a739a2dc1d1e76b79ff6ee12429 448 SUPERFAMILY SSF55874 320 445 1.09E-21 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08765 18aa7a739a2dc1d1e76b79ff6ee12429 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 390 2.5E-7 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS08765 18aa7a739a2dc1d1e76b79ff6ee12429 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 425 2.5E-7 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS08765 18aa7a739a2dc1d1e76b79ff6ee12429 448 Gene3D G3DSA:1.10.287.130 234 280 2.2E-4 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS08765 18aa7a739a2dc1d1e76b79ff6ee12429 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 343 446 5.3E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08765 18aa7a739a2dc1d1e76b79ff6ee12429 448 Gene3D G3DSA:3.30.565.10 310 445 1.6E-24 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS08765 18aa7a739a2dc1d1e76b79ff6ee12429 448 SMART SM00387 340 447 9.4E-18 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS07400 6d0d8d52e2265f0443ee66ca9300a474 280 Gene3D G3DSA:2.40.50.140 184 277 8.2E-33 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS07400 6d0d8d52e2265f0443ee66ca9300a474 280 SUPERFAMILY SSF50249 172 276 3.03E-29 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS07400 6d0d8d52e2265f0443ee66ca9300a474 280 SUPERFAMILY SSF56091 31 198 7.4E-36 T 05-07-2017 K08M4_RS07400 6d0d8d52e2265f0443ee66ca9300a474 280 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 175 198 - T 05-07-2017 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 K08M4_RS07400 6d0d8d52e2265f0443ee66ca9300a474 280 Pfam PF01068 ATP dependent DNA ligase domain 46 198 3.6E-6 T 05-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 K08M4_RS07400 6d0d8d52e2265f0443ee66ca9300a474 280 Pfam PF14743 DNA ligase OB-like domain 213 275 5.7E-26 T 05-07-2017 IPR029319 DNA ligase, OB-like domain K08M4_RS07400 6d0d8d52e2265f0443ee66ca9300a474 280 Gene3D G3DSA:3.30.1490.70 42 50 2.2E-5 T 05-07-2017 K08M4_RS07400 6d0d8d52e2265f0443ee66ca9300a474 280 Gene3D G3DSA:3.30.1490.70 151 183 2.2E-5 T 05-07-2017 K08M4_RS05380 e5987ff1edfbab18ca038cb23911948e 232 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 107 225 8.5E-32 T 05-07-2017 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 K08M4_RS05380 e5987ff1edfbab18ca038cb23911948e 232 PIRSF PIRSF037208 1 232 3.0E-80 T 05-07-2017 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic K08M4_RS05380 e5987ff1edfbab18ca038cb23911948e 232 SUPERFAMILY SSF55729 79 230 1.55E-23 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS05380 e5987ff1edfbab18ca038cb23911948e 232 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 16 86 1.3E-17 T 05-07-2017 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 K08M4_RS05380 e5987ff1edfbab18ca038cb23911948e 232 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 1 232 34.018 T 05-07-2017 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic K08M4_RS21345 2c5527abbcd2f7a469fa7cbc752396e3 446 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 36 413 6.1E-136 T 05-07-2017 K08M4_RS21345 2c5527abbcd2f7a469fa7cbc752396e3 446 Gene3D G3DSA:1.20.1250.20 22 220 6.7E-54 T 05-07-2017 K08M4_RS21345 2c5527abbcd2f7a469fa7cbc752396e3 446 Gene3D G3DSA:1.20.1250.20 244 434 4.0E-38 T 05-07-2017 K08M4_RS21345 2c5527abbcd2f7a469fa7cbc752396e3 446 Pfam PF07690 Major Facilitator Superfamily 37 396 3.4E-49 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS21345 2c5527abbcd2f7a469fa7cbc752396e3 446 PIRSF PIRSF002808 8 444 9.8E-141 T 05-07-2017 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 K08M4_RS21345 2c5527abbcd2f7a469fa7cbc752396e3 446 ProSitePatterns PS00942 glpT family of transporters signature. 151 167 - T 05-07-2017 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-3229133|Reactome: R-HSA-70153 K08M4_RS21345 2c5527abbcd2f7a469fa7cbc752396e3 446 SUPERFAMILY SSF103473 17 431 3.4E-80 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS05955 cc410919f8da86bd97c942ba70694611 431 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 272 429 5.3E-42 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS05955 cc410919f8da86bd97c942ba70694611 431 SUPERFAMILY SSF49785 39 210 5.7E-6 T 05-07-2017 IPR008979 Galactose-binding domain-like K08M4_RS05955 cc410919f8da86bd97c942ba70694611 431 Gene3D G3DSA:3.30.70.270 276 429 1.1E-45 T 05-07-2017 K08M4_RS05955 cc410919f8da86bd97c942ba70694611 431 SUPERFAMILY SSF55073 279 429 1.8E-40 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS05955 cc410919f8da86bd97c942ba70694611 431 Pfam PF00990 Diguanylate cyclase, GGDEF domain 274 426 4.3E-40 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS05955 cc410919f8da86bd97c942ba70694611 431 SMART SM00267 263 430 2.1E-48 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS05585 a98a7e3d8534c2a0ada610c94c02398f 260 Pfam PF13174 Tetratricopeptide repeat 218 250 2.5E-6 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS05585 a98a7e3d8534c2a0ada610c94c02398f 260 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 144 259 3.6E-37 T 05-07-2017 IPR014162 Tol-Pal system, YbgF K08M4_RS05585 a98a7e3d8534c2a0ada610c94c02398f 260 SMART SM00028 181 214 25.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS05585 a98a7e3d8534c2a0ada610c94c02398f 260 SMART SM00028 217 250 6.4 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS05585 a98a7e3d8534c2a0ada610c94c02398f 260 Gene3D G3DSA:1.25.40.10 146 253 2.4E-15 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS05585 a98a7e3d8534c2a0ada610c94c02398f 260 SUPERFAMILY SSF48452 144 255 4.11E-14 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS05585 a98a7e3d8534c2a0ada610c94c02398f 260 Pfam PF16331 TolA binding protein trimerisation 47 120 8.0E-23 T 05-07-2017 IPR032519 YbgF, trimerisation domain GO:0070206 K08M4_RS05585 a98a7e3d8534c2a0ada610c94c02398f 260 Pfam PF13432 Tetratricopeptide repeat 155 207 9.9E-7 T 05-07-2017 K08M4_RS03670 d4444f94f5a56612b3afe840e32b746d 474 Pfam PF00919 Uncharacterized protein family UPF0004 4 104 5.3E-29 T 05-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 K08M4_RS03670 d4444f94f5a56612b3afe840e32b746d 474 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 3 440 71.913 T 05-07-2017 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 K08M4_RS03670 d4444f94f5a56612b3afe840e32b746d 474 SUPERFAMILY SSF102114 125 371 6.54E-61 T 05-07-2017 K08M4_RS03670 d4444f94f5a56612b3afe840e32b746d 474 SMART SM00729 147 367 1.5E-62 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 K08M4_RS03670 d4444f94f5a56612b3afe840e32b746d 474 Pfam PF04055 Radical SAM superfamily 151 325 1.3E-27 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS03670 d4444f94f5a56612b3afe840e32b746d 474 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 437 9.0E-152 T 05-07-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 K08M4_RS03670 d4444f94f5a56612b3afe840e32b746d 474 Gene3D G3DSA:3.80.30.20 146 378 3.5E-77 T 05-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe K08M4_RS03670 d4444f94f5a56612b3afe840e32b746d 474 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 440 1.0E-198 T 05-07-2017 K08M4_RS03670 d4444f94f5a56612b3afe840e32b746d 474 Pfam PF01938 TRAM domain 379 440 5.7E-19 T 05-07-2017 IPR002792 TRAM domain K08M4_RS03670 d4444f94f5a56612b3afe840e32b746d 474 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 151 171 - T 05-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 SUPERFAMILY SSF53671 4 307 1.96E-103 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 Gene3D G3DSA:3.40.50.1370 7 144 2.2E-50 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 2.4E-27 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 2.4E-27 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 2.4E-27 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 2.4E-27 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 6.7E-43 T 05-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 7 307 39.08 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 8 305 5.9E-118 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 303 6.2E-34 T 05-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 Gene3D G3DSA:3.40.50.1370 145 292 2.2E-57 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 226 235 3.9E-37 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 3.9E-37 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 79 88 3.9E-37 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 3.9E-37 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 3.9E-37 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS01005 31a3a00081f9d44ca9d78026b9057e09 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 3.9E-37 T 05-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS05155 f81faaf61e8d9d51769ca3cc14c882ef 255 Pfam PF01026 TatD related DNase 3 253 2.3E-79 T 05-07-2017 IPR001130 TatD family GO:0016788 K08M4_RS05155 f81faaf61e8d9d51769ca3cc14c882ef 255 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 125 135 - T 05-07-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 K08M4_RS05155 f81faaf61e8d9d51769ca3cc14c882ef 255 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 8.5E-94 T 05-07-2017 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 K08M4_RS05155 f81faaf61e8d9d51769ca3cc14c882ef 255 SUPERFAMILY SSF51556 1 253 1.13E-89 T 05-07-2017 IPR032466 Metal-dependent hydrolase K08M4_RS05155 f81faaf61e8d9d51769ca3cc14c882ef 255 Gene3D G3DSA:3.20.20.140 1 253 4.5E-89 T 05-07-2017 K08M4_RS05155 f81faaf61e8d9d51769ca3cc14c882ef 255 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 05-07-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 K08M4_RS05155 f81faaf61e8d9d51769ca3cc14c882ef 255 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 190 206 - T 05-07-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 K08M4_RS05155 f81faaf61e8d9d51769ca3cc14c882ef 255 PIRSF PIRSF005902 1 255 1.6E-81 T 05-07-2017 IPR001130 TatD family GO:0016788 K08M4_RS01560 b0ac40e158a52bcd0cd3dcc2cdb35527 144 ProSitePatterns PS00475 Ribosomal protein L15 signature. 109 139 - T 05-07-2017 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01560 b0ac40e158a52bcd0cd3dcc2cdb35527 144 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 143 3.5E-31 T 05-07-2017 IPR021131 Ribosomal protein L18e/L15P K08M4_RS01560 b0ac40e158a52bcd0cd3dcc2cdb35527 144 Gene3D G3DSA:3.100.10.10 32 143 8.0E-27 T 05-07-2017 K08M4_RS01560 b0ac40e158a52bcd0cd3dcc2cdb35527 144 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 144 19.128 T 05-07-2017 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 K08M4_RS01560 b0ac40e158a52bcd0cd3dcc2cdb35527 144 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 2.5E-50 T 05-07-2017 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01560 b0ac40e158a52bcd0cd3dcc2cdb35527 144 SUPERFAMILY SSF52080 4 143 9.68E-47 T 05-07-2017 IPR021131 Ribosomal protein L18e/L15P K08M4_RS10665 972979f0c169112eb7cc6ca7a1d51694 528 Gene3D G3DSA:3.40.50.720 381 525 1.5E-49 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS10665 972979f0c169112eb7cc6ca7a1d51694 528 Pfam PF00999 Sodium/hydrogen exchanger family 3 349 4.0E-35 T 05-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 K08M4_RS10665 972979f0c169112eb7cc6ca7a1d51694 528 Pfam PF02254 TrkA-N domain 388 504 1.4E-17 T 05-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 K08M4_RS10665 972979f0c169112eb7cc6ca7a1d51694 528 SUPERFAMILY SSF51735 387 517 5.6E-14 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS00860 3a487938c88314cb521f0d209215ae45 308 Gene3D G3DSA:3.40.50.720 108 274 5.1E-52 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS00860 3a487938c88314cb521f0d209215ae45 308 Gene3D G3DSA:3.40.50.720 15 107 7.8E-5 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS00860 3a487938c88314cb521f0d209215ae45 308 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 100 273 6.2E-49 T 05-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 K08M4_RS00860 3a487938c88314cb521f0d209215ae45 308 SUPERFAMILY SSF51735 93 274 1.34E-47 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS00860 3a487938c88314cb521f0d209215ae45 308 SUPERFAMILY SSF52283 37 121 1.79E-7 T 05-07-2017 K08M4_RS17375 aa31ea47e255191ccda612b3527f471d 397 Gene3D G3DSA:1.20.1250.20 8 188 3.9E-28 T 05-07-2017 K08M4_RS17375 aa31ea47e255191ccda612b3527f471d 397 Gene3D G3DSA:1.20.1250.20 204 385 1.6E-9 T 05-07-2017 K08M4_RS17375 aa31ea47e255191ccda612b3527f471d 397 SUPERFAMILY SSF103473 8 387 2.62E-55 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS17375 aa31ea47e255191ccda612b3527f471d 397 Pfam PF07690 Major Facilitator Superfamily 15 263 9.0E-39 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS20350 2fe2192453814368f70a3e37df01d543 615 SUPERFAMILY SSF55486 3 550 5.25E-74 T 05-07-2017 K08M4_RS20350 2fe2192453814368f70a3e37df01d543 615 Pfam PF01432 Peptidase family M3 285 549 7.9E-16 T 05-07-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 K08M4_RS20350 2fe2192453814368f70a3e37df01d543 615 Gene3D G3DSA:3.40.390.10 280 375 2.0E-13 T 05-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 K08M4_RS20350 2fe2192453814368f70a3e37df01d543 615 Gene3D G3DSA:1.10.1370.10 376 551 4.4E-22 T 05-07-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 K08M4_RS20350 2fe2192453814368f70a3e37df01d543 615 Gene3D G3DSA:1.10.1370.10 103 261 4.4E-22 T 05-07-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 K08M4_RS18760 8b1df99f61b3d7a71c6d5bd2892b7925 286 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 227 6.6E-33 T 05-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 K08M4_RS18760 8b1df99f61b3d7a71c6d5bd2892b7925 286 Gene3D G3DSA:2.40.50.100 151 184 1.9E-21 T 05-07-2017 K08M4_RS18760 8b1df99f61b3d7a71c6d5bd2892b7925 286 Gene3D G3DSA:2.40.50.100 42 74 1.9E-21 T 05-07-2017 K08M4_RS18760 8b1df99f61b3d7a71c6d5bd2892b7925 286 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 41 228 1.3E-14 T 05-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain K08M4_RS18760 8b1df99f61b3d7a71c6d5bd2892b7925 286 SUPERFAMILY SSF111369 38 237 9.55E-25 T 05-07-2017 K08M4_RS20455 51e3d52471314952fa45fddb2f65378c 570 SUPERFAMILY SSF55120 362 567 1.5E-60 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS20455 51e3d52471314952fa45fddb2f65378c 570 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 414 428 - T 05-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS20455 51e3d52471314952fa45fddb2f65378c 570 Pfam PF00849 RNA pseudouridylate synthase 375 523 2.2E-30 T 05-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS18965 b32642ac5c9b9aac0fe1203eaab2f4a8 377 Pfam PF01571 Aminomethyltransferase folate-binding domain 15 259 3.8E-87 T 05-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal K08M4_RS18965 b32642ac5c9b9aac0fe1203eaab2f4a8 377 PIRSF PIRSF006487 1 377 7.6E-81 T 05-07-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 K08M4_RS18965 b32642ac5c9b9aac0fe1203eaab2f4a8 377 Gene3D G3DSA:3.30.1360.120 135 236 1.2E-29 T 05-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 K08M4_RS18965 b32642ac5c9b9aac0fe1203eaab2f4a8 377 Gene3D G3DSA:2.40.30.110 291 376 8.4E-28 T 05-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 K08M4_RS18965 b32642ac5c9b9aac0fe1203eaab2f4a8 377 SUPERFAMILY SSF103025 9 286 1.73E-89 T 05-07-2017 K08M4_RS18965 b32642ac5c9b9aac0fe1203eaab2f4a8 377 SUPERFAMILY SSF101790 283 376 2.94E-26 T 05-07-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain K08M4_RS18965 b32642ac5c9b9aac0fe1203eaab2f4a8 377 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 11 371 2.7E-107 T 05-07-2017 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 K08M4_RS18965 b32642ac5c9b9aac0fe1203eaab2f4a8 377 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 273 367 1.5E-22 T 05-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 K08M4_RS18965 b32642ac5c9b9aac0fe1203eaab2f4a8 377 Gene3D G3DSA:3.30.70.1400 61 134 3.4E-33 T 05-07-2017 K08M4_RS12340 4a805a75f740f9010b510495aa52b077 259 Pfam PF10411 Disulfide bond isomerase protein N-terminus 43 97 4.4E-14 T 05-07-2017 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal K08M4_RS12340 4a805a75f740f9010b510495aa52b077 259 Gene3D G3DSA:3.40.30.10 125 259 4.0E-42 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS12340 4a805a75f740f9010b510495aa52b077 259 SUPERFAMILY SSF52833 119 259 1.34E-35 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS12340 4a805a75f740f9010b510495aa52b077 259 Pfam PF13098 Thioredoxin-like domain 129 257 8.8E-25 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS12340 4a805a75f740f9010b510495aa52b077 259 Gene3D G3DSA:3.10.450.70 42 99 3.3E-20 T 05-07-2017 IPR009094 Disulphide bond isomerase, DsbC, N-terminal K08M4_RS12340 4a805a75f740f9010b510495aa52b077 259 SUPERFAMILY SSF54423 42 99 6.8E-13 T 05-07-2017 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal K08M4_RS00610 4e550f2f2a07e770b003ac514604a358 206 SUPERFAMILY SSF46785 3 69 1.51E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS00610 4e550f2f2a07e770b003ac514604a358 206 Hamap MF_00015 LexA repressor [lexA]. 3 203 31.464 T 05-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 K08M4_RS00610 4e550f2f2a07e770b003ac514604a358 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 115 125 1.5E-13 T 05-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 K08M4_RS00610 4e550f2f2a07e770b003ac514604a358 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 154 166 1.5E-13 T 05-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 K08M4_RS00610 4e550f2f2a07e770b003ac514604a358 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 126 137 1.5E-13 T 05-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 K08M4_RS00610 4e550f2f2a07e770b003ac514604a358 206 Gene3D G3DSA:2.10.109.10 80 203 7.9E-45 T 05-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain K08M4_RS00610 4e550f2f2a07e770b003ac514604a358 206 TIGRFAM TIGR00498 lexA: repressor LexA 1 203 4.5E-80 T 05-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 K08M4_RS00610 4e550f2f2a07e770b003ac514604a358 206 Pfam PF00717 Peptidase S24-like 118 184 2.0E-15 T 05-07-2017 IPR019759 Peptidase S24/S26A/S26B K08M4_RS00610 4e550f2f2a07e770b003ac514604a358 206 SUPERFAMILY SSF51306 79 202 1.92E-36 T 05-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C K08M4_RS00610 4e550f2f2a07e770b003ac514604a358 206 Pfam PF01726 LexA DNA binding domain 1 65 2.9E-28 T 05-07-2017 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 K08M4_RS00610 4e550f2f2a07e770b003ac514604a358 206 Gene3D G3DSA:1.10.10.10 1 69 5.8E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS03570 48d3d0afaae1e947aa8f2edaec1f611a 132 Pfam PF04241 Protein of unknown function (DUF423) 20 110 1.1E-29 T 05-07-2017 IPR006696 Protein of unknown function DUF423 K08M4_RS15730 0ec05c00426fc2dfad8cd993ac4e42fe 247 PIRSF PIRSF028234 1 247 1.4E-83 T 05-07-2017 IPR016876 Uncharacterised conserved protein UCP028234 K08M4_RS15730 0ec05c00426fc2dfad8cd993ac4e42fe 247 Pfam PF12847 Methyltransferase domain 3 166 8.8E-27 T 05-07-2017 K08M4_RS15730 0ec05c00426fc2dfad8cd993ac4e42fe 247 SUPERFAMILY SSF53335 16 152 1.6E-5 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS15730 0ec05c00426fc2dfad8cd993ac4e42fe 247 Gene3D G3DSA:3.40.50.150 19 102 1.7E-5 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS15720 706cff0d279dc97acd83b23dbe803ef3 267 SUPERFAMILY SSF63380 8 109 2.87E-19 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 K08M4_RS15720 706cff0d279dc97acd83b23dbe803ef3 267 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 120 139 4.2E-5 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS15720 706cff0d279dc97acd83b23dbe803ef3 267 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 228 236 4.2E-5 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS15720 706cff0d279dc97acd83b23dbe803ef3 267 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 167 178 4.2E-5 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS15720 706cff0d279dc97acd83b23dbe803ef3 267 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 55 62 4.2E-5 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS15720 706cff0d279dc97acd83b23dbe803ef3 267 Pfam PF00175 Oxidoreductase NAD-binding domain 121 242 8.8E-16 T 05-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 K08M4_RS15720 706cff0d279dc97acd83b23dbe803ef3 267 Pfam PF00970 Oxidoreductase FAD-binding domain 23 98 6.6E-7 T 05-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 K08M4_RS15720 706cff0d279dc97acd83b23dbe803ef3 267 Gene3D G3DSA:3.40.50.80 106 267 1.3E-40 T 05-07-2017 K08M4_RS15720 706cff0d279dc97acd83b23dbe803ef3 267 Gene3D G3DSA:2.40.30.10 8 105 1.5E-26 T 05-07-2017 K08M4_RS15720 706cff0d279dc97acd83b23dbe803ef3 267 SUPERFAMILY SSF52343 115 267 1.31E-29 T 05-07-2017 K08M4_RS04855 0c20d84dfe63ddfc4a302e32d4dc2e9a 211 TIGRFAM TIGR01083 nth: endonuclease III 5 194 2.3E-86 T 05-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 K08M4_RS04855 0c20d84dfe63ddfc4a302e32d4dc2e9a 211 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 05-07-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 K08M4_RS04855 0c20d84dfe63ddfc4a302e32d4dc2e9a 211 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 7.6E-5 T 05-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 K08M4_RS04855 0c20d84dfe63ddfc4a302e32d4dc2e9a 211 SUPERFAMILY SSF48150 6 208 2.83E-69 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 K08M4_RS04855 0c20d84dfe63ddfc4a302e32d4dc2e9a 211 SMART SM00478 38 185 8.4E-52 T 05-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 K08M4_RS04855 0c20d84dfe63ddfc4a302e32d4dc2e9a 211 Gene3D G3DSA:1.10.1670.10 123 208 6.4E-35 T 05-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 K08M4_RS04855 0c20d84dfe63ddfc4a302e32d4dc2e9a 211 SMART SM00525 186 206 1.8E-5 T 05-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 K08M4_RS04855 0c20d84dfe63ddfc4a302e32d4dc2e9a 211 Hamap MF_00942 Endonuclease III [nth]. 1 209 36.968 T 05-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 K08M4_RS04855 0c20d84dfe63ddfc4a302e32d4dc2e9a 211 Pfam PF00633 Helix-hairpin-helix motif 100 127 3.5E-7 T 05-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 K08M4_RS04855 0c20d84dfe63ddfc4a302e32d4dc2e9a 211 Gene3D G3DSA:1.10.340.30 23 122 5.8E-32 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 K08M4_RS04855 0c20d84dfe63ddfc4a302e32d4dc2e9a 211 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 168 5.7E-18 T 05-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 K08M4_RS04855 0c20d84dfe63ddfc4a302e32d4dc2e9a 211 PIRSF PIRSF001435 1 210 1.8E-49 T 05-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 K08M4_RS04855 0c20d84dfe63ddfc4a302e32d4dc2e9a 211 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 05-07-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 K08M4_RS05675 4818dfb7222a9d67675d3ad08ccaf8ce 225 Gene3D G3DSA:3.40.50.2300 2 121 1.1E-38 T 05-07-2017 K08M4_RS05675 4818dfb7222a9d67675d3ad08ccaf8ce 225 SMART SM00862 147 221 4.6E-13 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS05675 4818dfb7222a9d67675d3ad08ccaf8ce 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 221 3.1E-16 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS05675 4818dfb7222a9d67675d3ad08ccaf8ce 225 SUPERFAMILY SSF46894 123 222 1.5E-20 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS05675 4818dfb7222a9d67675d3ad08ccaf8ce 225 Pfam PF00072 Response regulator receiver domain 4 113 4.3E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS05675 4818dfb7222a9d67675d3ad08ccaf8ce 225 SMART SM00448 2 113 1.4E-36 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS05675 4818dfb7222a9d67675d3ad08ccaf8ce 225 Gene3D G3DSA:1.10.10.10 125 222 1.7E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05675 4818dfb7222a9d67675d3ad08ccaf8ce 225 SUPERFAMILY SSF52172 1 124 1.71E-39 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS19205 ee1360f59db9e96ed5b6479e582548cc 358 Gene3D G3DSA:1.25.40.10 180 326 2.6E-15 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS19205 ee1360f59db9e96ed5b6479e582548cc 358 SUPERFAMILY SSF48452 182 326 2.37E-15 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS19205 ee1360f59db9e96ed5b6479e582548cc 358 SUPERFAMILY SSF48371 60 240 8.06E-7 T 05-07-2017 IPR016024 Armadillo-type fold GO:0005488 K08M4_RS19205 ee1360f59db9e96ed5b6479e582548cc 358 Gene3D G3DSA:1.25.10.10 72 147 4.8E-5 T 05-07-2017 IPR011989 Armadillo-like helical K08M4_RS04885 b4d8a6c08f0146def51b3cdfd590ecbf 192 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 190 3.6E-61 T 05-07-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 K08M4_RS04885 b4d8a6c08f0146def51b3cdfd590ecbf 192 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 3 191 1.7E-89 T 05-07-2017 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 K08M4_RS04885 b4d8a6c08f0146def51b3cdfd590ecbf 192 PIRSF PIRSF006102 1 192 1.7E-63 T 05-07-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 K08M4_RS04885 b4d8a6c08f0146def51b3cdfd590ecbf 192 Hamap MF_00459 Electron transport complex subunit RsxA [rsxA]. 2 191 26.348 T 05-07-2017 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 K08M4_RS15575 6f6084102732adc5e0424b1f87720236 295 Pfam PF03466 LysR substrate binding domain 88 289 9.2E-17 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS15575 6f6084102732adc5e0424b1f87720236 295 SUPERFAMILY SSF53850 89 293 7.91E-27 T 05-07-2017 K08M4_RS15575 6f6084102732adc5e0424b1f87720236 295 SUPERFAMILY SSF46785 3 86 9.8E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15575 6f6084102732adc5e0424b1f87720236 295 Gene3D G3DSA:1.10.10.10 2 80 4.9E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15575 6f6084102732adc5e0424b1f87720236 295 Gene3D G3DSA:3.40.190.10 89 176 1.3E-9 T 05-07-2017 K08M4_RS15575 6f6084102732adc5e0424b1f87720236 295 Gene3D G3DSA:3.40.190.10 177 254 7.8E-5 T 05-07-2017 K08M4_RS15575 6f6084102732adc5e0424b1f87720236 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.2E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS21065 d14436bb198bcf5d7338249f85d40515 283 SUPERFAMILY SSF53850 94 275 8.07E-21 T 05-07-2017 K08M4_RS21065 d14436bb198bcf5d7338249f85d40515 283 Gene3D G3DSA:1.10.10.10 7 92 1.6E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21065 d14436bb198bcf5d7338249f85d40515 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 7.5E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS21065 d14436bb198bcf5d7338249f85d40515 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 7.5E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS21065 d14436bb198bcf5d7338249f85d40515 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 7.5E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS21065 d14436bb198bcf5d7338249f85d40515 283 Pfam PF03466 LysR substrate binding domain 94 264 3.5E-18 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS21065 d14436bb198bcf5d7338249f85d40515 283 SUPERFAMILY SSF46785 7 93 1.31E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21065 d14436bb198bcf5d7338249f85d40515 283 Gene3D G3DSA:3.40.190.10 93 198 2.7E-14 T 05-07-2017 K08M4_RS21065 d14436bb198bcf5d7338249f85d40515 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 1.1E-18 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS16870 d9157502433c871c0095aa431f0c98fe 132 Gene3D G3DSA:2.20.25.10 1 34 1.6E-18 T 05-07-2017 K08M4_RS16870 d9157502433c871c0095aa431f0c98fe 132 Pfam PF02566 OsmC-like protein 29 127 1.0E-16 T 05-07-2017 IPR003718 OsmC/Ohr family K08M4_RS16870 d9157502433c871c0095aa431f0c98fe 132 SUPERFAMILY SSF82784 1 131 5.63E-39 T 05-07-2017 IPR003718 OsmC/Ohr family K08M4_RS16870 d9157502433c871c0095aa431f0c98fe 132 Gene3D G3DSA:3.30.300.20 35 132 2.1E-35 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta K08M4_RS09130 5e5e7df720e1ceca9b6352b74dd18f1c 539 SUPERFAMILY SSF141072 162 262 9.02E-7 T 05-07-2017 K08M4_RS09130 5e5e7df720e1ceca9b6352b74dd18f1c 539 SUPERFAMILY SSF141072 51 159 1.57E-8 T 05-07-2017 K08M4_RS09130 5e5e7df720e1ceca9b6352b74dd18f1c 539 Pfam PF07603 Protein of unknown function (DUF1566) 378 523 3.1E-10 T 05-07-2017 IPR011460 Protein of unknown function DUF1566 K08M4_RS00815 45fc419926e7318924eaeb8d87404a30 234 PIRSF PIRSF002155 1 227 1.4E-77 T 05-07-2017 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS00815 45fc419926e7318924eaeb8d87404a30 234 Gene3D G3DSA:3.40.50.790 69 159 1.3E-40 T 05-07-2017 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich K08M4_RS00815 45fc419926e7318924eaeb8d87404a30 234 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 5.6E-106 T 05-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 K08M4_RS00815 45fc419926e7318924eaeb8d87404a30 234 SUPERFAMILY SSF56808 6 225 1.96E-81 T 05-07-2017 IPR023674 Ribosomal protein L1-like K08M4_RS00815 45fc419926e7318924eaeb8d87404a30 234 Gene3D G3DSA:3.30.190.20 18 68 1.1E-46 T 05-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 K08M4_RS00815 45fc419926e7318924eaeb8d87404a30 234 Gene3D G3DSA:3.30.190.20 161 225 1.1E-46 T 05-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 K08M4_RS00815 45fc419926e7318924eaeb8d87404a30 234 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.012 T 05-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 K08M4_RS00815 45fc419926e7318924eaeb8d87404a30 234 Pfam PF00687 Ribosomal protein L1p/L10e family 30 219 6.9E-52 T 05-07-2017 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein K08M4_RS00815 45fc419926e7318924eaeb8d87404a30 234 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 05-07-2017 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS09690 7945e560cd2454fb775573b72240e765 350 SUPERFAMILY SSF102114 5 310 1.96E-89 T 05-07-2017 K08M4_RS09690 7945e560cd2454fb775573b72240e765 350 SMART SM00729 43 255 4.1E-39 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 K08M4_RS09690 7945e560cd2454fb775573b72240e765 350 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 220 310 4.2E-20 T 05-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 K08M4_RS09690 7945e560cd2454fb775573b72240e765 350 Hamap MF_01694 Biotin synthase [bioB]. 5 313 41.29 T 05-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 K08M4_RS09690 7945e560cd2454fb775573b72240e765 350 PIRSF PIRSF001619 1 319 1.9E-137 T 05-07-2017 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 K08M4_RS09690 7945e560cd2454fb775573b72240e765 350 TIGRFAM TIGR00433 bioB: biotin synthase 15 310 7.8E-124 T 05-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 K08M4_RS09690 7945e560cd2454fb775573b72240e765 350 Pfam PF04055 Radical SAM superfamily 50 200 4.1E-15 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS09690 7945e560cd2454fb775573b72240e765 350 Gene3D G3DSA:3.20.20.70 5 313 2.5E-101 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS09690 7945e560cd2454fb775573b72240e765 350 SMART SM00876 220 312 2.2E-44 T 05-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 K08M4_RS03325 78eb04a6442736d7c691ca9f64b7accb 562 SUPERFAMILY SSF56801 15 548 6.8E-111 T 05-07-2017 K08M4_RS03325 78eb04a6442736d7c691ca9f64b7accb 562 Gene3D G3DSA:2.30.38.10 378 435 2.4E-16 T 05-07-2017 K08M4_RS03325 78eb04a6442736d7c691ca9f64b7accb 562 Pfam PF00501 AMP-binding enzyme 25 441 2.6E-88 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 K08M4_RS03325 78eb04a6442736d7c691ca9f64b7accb 562 Gene3D G3DSA:3.40.50.980 17 189 4.0E-31 T 05-07-2017 K08M4_RS03325 78eb04a6442736d7c691ca9f64b7accb 562 Gene3D G3DSA:3.40.50.980 190 369 1.6E-26 T 05-07-2017 K08M4_RS03325 78eb04a6442736d7c691ca9f64b7accb 562 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 05-07-2017 IPR020845 AMP-binding, conserved site K08M4_RS12825 3e66ca2a531ffa27469a217c3162a658 147 Gene3D G3DSA:1.10.10.410 91 147 1.1E-21 T 05-07-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal K08M4_RS12825 3e66ca2a531ffa27469a217c3162a658 147 SUPERFAMILY SSF89095 1 146 1.99E-41 T 05-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 K08M4_RS12825 3e66ca2a531ffa27469a217c3162a658 147 Pfam PF09424 Yqey-like protein 5 146 7.9E-55 T 05-07-2017 IPR019004 Uncharacterised domain YOR215C, mitochondrial K08M4_RS12825 3e66ca2a531ffa27469a217c3162a658 147 Gene3D G3DSA:1.10.1510.10 1 90 2.7E-32 T 05-07-2017 K08M4_RS17695 b9102bdb88d050e56602b088fd92cbea 157 SUPERFAMILY SSF54534 13 157 1.81E-49 T 05-07-2017 K08M4_RS17695 b9102bdb88d050e56602b088fd92cbea 157 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 26 59 5.0E-9 T 05-07-2017 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 K08M4_RS17695 b9102bdb88d050e56602b088fd92cbea 157 Gene3D G3DSA:3.10.50.40 26 157 7.2E-52 T 05-07-2017 K08M4_RS17695 b9102bdb88d050e56602b088fd92cbea 157 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 66 154 2.3E-27 T 05-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 K08M4_RS00480 319a7abf48aadd8e2459dbc56bd5d00a 205 Pfam PF01810 LysE type translocator 15 202 3.4E-35 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS00480 319a7abf48aadd8e2459dbc56bd5d00a 205 PIRSF PIRSF006324 1 205 2.4E-55 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS09765 309c4d474ed5643244e92a9e5843e892 391 Pfam PF13176 Tetratricopeptide repeat 71 94 0.025 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS09765 309c4d474ed5643244e92a9e5843e892 391 SMART SM00028 216 249 20.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS09765 309c4d474ed5643244e92a9e5843e892 391 SMART SM00028 182 215 0.028 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS09765 309c4d474ed5643244e92a9e5843e892 391 SMART SM00028 69 102 81.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS09765 309c4d474ed5643244e92a9e5843e892 391 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 4 389 36.751 T 05-07-2017 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 K08M4_RS09765 309c4d474ed5643244e92a9e5843e892 391 Gene3D G3DSA:1.25.40.10 33 299 8.0E-27 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS09765 309c4d474ed5643244e92a9e5843e892 391 SUPERFAMILY SSF48452 26 141 2.76E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS09765 309c4d474ed5643244e92a9e5843e892 391 SUPERFAMILY SSF48452 109 281 9.1E-18 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS03135 25c11b63076d620866ae31099a227fea 317 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 10 218 1.7E-86 T 05-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS03135 25c11b63076d620866ae31099a227fea 317 Gene3D G3DSA:2.30.130.10 249 312 8.5E-26 T 05-07-2017 IPR015947 PUA-like domain K08M4_RS03135 25c11b63076d620866ae31099a227fea 317 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 10 308 19.173 T 05-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS03135 25c11b63076d620866ae31099a227fea 317 SUPERFAMILY SSF88697 250 310 1.74E-12 T 05-07-2017 IPR015947 PUA-like domain K08M4_RS03135 25c11b63076d620866ae31099a227fea 317 SUPERFAMILY SSF55120 9 247 7.48E-84 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS03135 25c11b63076d620866ae31099a227fea 317 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 251 308 7.6E-18 T 05-07-2017 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS03135 25c11b63076d620866ae31099a227fea 317 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 32 179 1.4E-58 T 05-07-2017 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 K08M4_RS03135 25c11b63076d620866ae31099a227fea 317 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 180 247 1.8E-23 T 05-07-2017 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 K08M4_RS02110 199fedbf4a1089c3d855d4b06b7654f9 352 Gene3D G3DSA:1.10.1670.10 120 222 9.6E-38 T 05-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 K08M4_RS02110 199fedbf4a1089c3d855d4b06b7654f9 352 Gene3D G3DSA:3.90.79.10 227 345 3.5E-22 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS02110 199fedbf4a1089c3d855d4b06b7654f9 352 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 165 1.6E-20 T 05-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 K08M4_RS02110 199fedbf4a1089c3d855d4b06b7654f9 352 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 190 206 - T 05-07-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 K08M4_RS02110 199fedbf4a1089c3d855d4b06b7654f9 352 SMART SM00525 189 209 3.4E-4 T 05-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 K08M4_RS02110 199fedbf4a1089c3d855d4b06b7654f9 352 Pfam PF00633 Helix-hairpin-helix motif 98 125 4.1E-7 T 05-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 K08M4_RS02110 199fedbf4a1089c3d855d4b06b7654f9 352 Gene3D G3DSA:1.10.340.30 20 119 4.8E-44 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 K08M4_RS02110 199fedbf4a1089c3d855d4b06b7654f9 352 SMART SM00478 37 188 1.4E-45 T 05-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 K08M4_RS02110 199fedbf4a1089c3d855d4b06b7654f9 352 SUPERFAMILY SSF48150 3 223 1.04E-73 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 K08M4_RS02110 199fedbf4a1089c3d855d4b06b7654f9 352 SUPERFAMILY SSF55811 218 345 2.4E-27 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS02110 199fedbf4a1089c3d855d4b06b7654f9 352 Pfam PF14815 NUDIX domain 231 343 8.7E-23 T 05-07-2017 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 K08M4_RS02110 199fedbf4a1089c3d855d4b06b7654f9 352 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 4 266 2.6E-125 T 05-07-2017 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 K08M4_RS07650 81fde650339f8988e49a792d01573770 324 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 37 83 3.9E-24 T 05-07-2017 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal K08M4_RS07650 81fde650339f8988e49a792d01573770 324 PIRSF PIRSF000006 1 322 3.1E-110 T 05-07-2017 IPR004678 Cytochrome c oxidase cbb3-type, subunit III K08M4_RS07650 81fde650339f8988e49a792d01573770 324 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 113 321 2.5E-56 T 05-07-2017 IPR004678 Cytochrome c oxidase cbb3-type, subunit III K08M4_RS07650 81fde650339f8988e49a792d01573770 324 PRINTS PR00605 Class IC cytochrome C signature 164 175 2.0E-5 T 05-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 K08M4_RS07650 81fde650339f8988e49a792d01573770 324 PRINTS PR00605 Class IC cytochrome C signature 293 315 2.0E-5 T 05-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 K08M4_RS07650 81fde650339f8988e49a792d01573770 324 Gene3D G3DSA:1.10.760.10 245 322 1.9E-24 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS07650 81fde650339f8988e49a792d01573770 324 SUPERFAMILY SSF46626 55 78 4.87E-31 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS07650 81fde650339f8988e49a792d01573770 324 SUPERFAMILY SSF46626 145 238 4.87E-31 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS07650 81fde650339f8988e49a792d01573770 324 SUPERFAMILY SSF46626 239 321 4.8E-20 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS07650 81fde650339f8988e49a792d01573770 324 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 241 315 3.2E-9 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS07650 81fde650339f8988e49a792d01573770 324 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 154 227 2.9E-13 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS07650 81fde650339f8988e49a792d01573770 324 Gene3D G3DSA:1.10.760.10 60 82 4.5E-33 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS07650 81fde650339f8988e49a792d01573770 324 Gene3D G3DSA:1.10.760.10 149 244 4.5E-33 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS17865 06dee6e28f24c28fb31c1cefa1fddcc9 96 Gene3D G3DSA:3.30.70.900 4 95 3.6E-31 T 05-07-2017 K08M4_RS17865 06dee6e28f24c28fb31c1cefa1fddcc9 96 SUPERFAMILY SSF54909 1 90 9.91E-30 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel K08M4_RS17865 06dee6e28f24c28fb31c1cefa1fddcc9 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 5 78 3.8E-16 T 05-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain K08M4_RS21240 8938296b07b2121c9ab3502bfe22d41e 363 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS21240 8938296b07b2121c9ab3502bfe22d41e 363 Gene3D G3DSA:2.40.50.100 347 361 2.7E-7 T 05-07-2017 K08M4_RS21240 8938296b07b2121c9ab3502bfe22d41e 363 Gene3D G3DSA:2.40.50.100 239 286 2.7E-7 T 05-07-2017 K08M4_RS21240 8938296b07b2121c9ab3502bfe22d41e 363 Pfam PF00005 ABC transporter 20 161 2.2E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS21240 8938296b07b2121c9ab3502bfe22d41e 363 SUPERFAMILY SSF50331 237 359 2.67E-14 T 05-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal K08M4_RS21240 8938296b07b2121c9ab3502bfe22d41e 363 SMART SM00382 28 210 2.9E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS21240 8938296b07b2121c9ab3502bfe22d41e 363 SUPERFAMILY SSF52540 4 243 3.65E-86 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21240 8938296b07b2121c9ab3502bfe22d41e 363 Gene3D G3DSA:3.40.50.300 3 236 4.5E-78 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17955 8bb0bc8acd3a9562dc2a49607f2581da 262 Pfam PF01764 Lipase (class 3) 60 204 2.9E-25 T 05-07-2017 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 K08M4_RS17955 8bb0bc8acd3a9562dc2a49607f2581da 262 SUPERFAMILY SSF53474 10 228 5.96E-33 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS17955 8bb0bc8acd3a9562dc2a49607f2581da 262 Gene3D G3DSA:3.40.50.1820 8 231 2.3E-39 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS01325 c84ef3b48296d28fb5528d717a7ecf1a 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 4.4E-5 T 05-07-2017 K08M4_RS01325 c84ef3b48296d28fb5528d717a7ecf1a 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 4.4E-5 T 05-07-2017 K08M4_RS01325 c84ef3b48296d28fb5528d717a7ecf1a 192 PRINTS PR00097 Anthranilate synthase component II signature 99 107 3.4E-36 T 05-07-2017 K08M4_RS01325 c84ef3b48296d28fb5528d717a7ecf1a 192 PRINTS PR00097 Anthranilate synthase component II signature 119 131 3.4E-36 T 05-07-2017 K08M4_RS01325 c84ef3b48296d28fb5528d717a7ecf1a 192 PRINTS PR00097 Anthranilate synthase component II signature 2 16 3.4E-36 T 05-07-2017 K08M4_RS01325 c84ef3b48296d28fb5528d717a7ecf1a 192 PRINTS PR00097 Anthranilate synthase component II signature 74 85 3.4E-36 T 05-07-2017 K08M4_RS01325 c84ef3b48296d28fb5528d717a7ecf1a 192 PRINTS PR00097 Anthranilate synthase component II signature 47 56 3.4E-36 T 05-07-2017 K08M4_RS01325 c84ef3b48296d28fb5528d717a7ecf1a 192 PRINTS PR00097 Anthranilate synthase component II signature 169 182 3.4E-36 T 05-07-2017 K08M4_RS01325 c84ef3b48296d28fb5528d717a7ecf1a 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 4.2E-13 T 05-07-2017 K08M4_RS01325 c84ef3b48296d28fb5528d717a7ecf1a 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 4.2E-13 T 05-07-2017 K08M4_RS01325 c84ef3b48296d28fb5528d717a7ecf1a 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 4.2E-13 T 05-07-2017 K08M4_RS01325 c84ef3b48296d28fb5528d717a7ecf1a 192 SUPERFAMILY SSF52317 1 191 1.73E-54 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS01325 c84ef3b48296d28fb5528d717a7ecf1a 192 Pfam PF00117 Glutamine amidotransferase class-I 4 190 3.0E-54 T 05-07-2017 IPR017926 Glutamine amidotransferase K08M4_RS01325 c84ef3b48296d28fb5528d717a7ecf1a 192 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 192 3.4E-86 T 05-07-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 K08M4_RS01325 c84ef3b48296d28fb5528d717a7ecf1a 192 Gene3D G3DSA:3.40.50.880 2 191 3.0E-66 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS07120 90c793982f5242edfc48f02b889071e7 152 Gene3D G3DSA:3.30.310.70 22 145 7.8E-32 T 05-07-2017 IPR005180 Domain of unknown function DUF302 K08M4_RS07120 90c793982f5242edfc48f02b889071e7 152 SUPERFAMILY SSF103247 25 146 3.66E-36 T 05-07-2017 IPR005180 Domain of unknown function DUF302 K08M4_RS07120 90c793982f5242edfc48f02b889071e7 152 Pfam PF03625 Domain of unknown function DUF302 55 117 1.3E-20 T 05-07-2017 IPR005180 Domain of unknown function DUF302 K08M4_RS03815 571cd6d229bf9930e55bbc69b0c2441d 290 Gene3D G3DSA:3.40.50.150 92 287 2.6E-64 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS03815 571cd6d229bf9930e55bbc69b0c2441d 290 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 7 288 44.089 T 05-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 K08M4_RS03815 571cd6d229bf9930e55bbc69b0c2441d 290 Gene3D G3DSA:1.10.8.10 6 90 1.8E-28 T 05-07-2017 K08M4_RS03815 571cd6d229bf9930e55bbc69b0c2441d 290 SUPERFAMILY SSF53335 8 288 2.16E-56 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS03815 571cd6d229bf9930e55bbc69b0c2441d 290 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 193 199 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 K08M4_RS03815 571cd6d229bf9930e55bbc69b0c2441d 290 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 12 288 1.2E-76 T 05-07-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 K08M4_RS03815 571cd6d229bf9930e55bbc69b0c2441d 290 Pfam PF13847 Methyltransferase domain 117 253 2.2E-17 T 05-07-2017 IPR025714 Methyltransferase domain K08M4_RS03815 571cd6d229bf9930e55bbc69b0c2441d 290 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 29 284 1.2E-89 T 05-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 K08M4_RS17445 edaa69cc3ab5e36923263163035cfdff 437 SUPERFAMILY SSF111369 67 155 4.84E-7 T 05-07-2017 K08M4_RS17445 edaa69cc3ab5e36923263163035cfdff 437 Gene3D G3DSA:2.40.50.100 68 97 7.1E-13 T 05-07-2017 K08M4_RS17445 edaa69cc3ab5e36923263163035cfdff 437 Gene3D G3DSA:2.40.50.100 286 320 7.1E-13 T 05-07-2017 K08M4_RS17445 edaa69cc3ab5e36923263163035cfdff 437 Gene3D G3DSA:1.20.1600.10 144 233 9.8E-7 T 05-07-2017 K08M4_RS17445 edaa69cc3ab5e36923263163035cfdff 437 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 301 322 2.6E-41 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS17445 edaa69cc3ab5e36923263163035cfdff 437 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 334 358 2.6E-41 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS17445 edaa69cc3ab5e36923263163035cfdff 437 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 75 95 2.6E-41 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS17445 edaa69cc3ab5e36923263163035cfdff 437 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 416 436 2.6E-41 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS17445 edaa69cc3ab5e36923263163035cfdff 437 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 401 416 2.6E-41 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS17445 edaa69cc3ab5e36923263163035cfdff 437 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 358 381 2.6E-41 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS17445 edaa69cc3ab5e36923263163035cfdff 437 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 33 56 2.6E-41 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS17445 edaa69cc3ab5e36923263163035cfdff 437 Pfam PF13533 Biotin-lipoyl like 67 110 4.8E-8 T 05-07-2017 K08M4_RS17445 edaa69cc3ab5e36923263163035cfdff 437 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 23 437 4.0E-111 T 05-07-2017 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 K08M4_RS17445 edaa69cc3ab5e36923263163035cfdff 437 SUPERFAMILY SSF56954 143 231 2.88E-6 T 05-07-2017 K08M4_RS17445 edaa69cc3ab5e36923263163035cfdff 437 Pfam PF13437 HlyD family secretion protein 289 396 2.7E-15 T 05-07-2017 K08M4_RS12455 f4408bb9f598d0be699f89f1269363c5 317 SMART SM00729 23 249 1.0E-46 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 K08M4_RS12455 f4408bb9f598d0be699f89f1269363c5 317 Pfam PF16199 Radical_SAM C-terminal domain 211 281 1.1E-18 T 05-07-2017 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 K08M4_RS12455 f4408bb9f598d0be699f89f1269363c5 317 SUPERFAMILY SSF102114 13 270 1.31E-49 T 05-07-2017 K08M4_RS12455 f4408bb9f598d0be699f89f1269363c5 317 Gene3D G3DSA:3.80.30.20 22 254 6.8E-34 T 05-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe K08M4_RS12455 f4408bb9f598d0be699f89f1269363c5 317 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 6 301 1.2E-130 T 05-07-2017 IPR005911 Protein YhcC-like GO:0051536 K08M4_RS12455 f4408bb9f598d0be699f89f1269363c5 317 Pfam PF04055 Radical SAM superfamily 43 204 1.3E-17 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS03515 51ddf701113df507e081b0026b5e7af1 155 Pfam PF01029 NusB family 11 149 6.3E-35 T 05-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 K08M4_RS03515 51ddf701113df507e081b0026b5e7af1 155 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 10 150 6.0E-41 T 05-07-2017 IPR011605 NusB antitermination factor GO:0006353 K08M4_RS03515 51ddf701113df507e081b0026b5e7af1 155 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 8 153 22.392 T 05-07-2017 IPR011605 NusB antitermination factor GO:0006353 K08M4_RS03515 51ddf701113df507e081b0026b5e7af1 155 Gene3D G3DSA:1.10.940.10 6 154 1.1E-41 T 05-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 K08M4_RS03515 51ddf701113df507e081b0026b5e7af1 155 SUPERFAMILY SSF48013 7 153 3.14E-38 T 05-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 K08M4_RS16470 9d887158fde1c665f71a8fd7458fe088 296 SUPERFAMILY SSF103481 46 144 8.37E-9 T 05-07-2017 K08M4_RS16470 9d887158fde1c665f71a8fd7458fe088 296 Pfam PF00892 EamA-like transporter family 9 143 4.6E-7 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS16470 9d887158fde1c665f71a8fd7458fe088 296 Pfam PF00892 EamA-like transporter family 152 283 2.0E-11 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS16470 9d887158fde1c665f71a8fd7458fe088 296 SUPERFAMILY SSF103481 188 286 1.12E-9 T 05-07-2017 K08M4_RS21725 838ba074e115efaeb0f1759b7e61f7ef 266 Pfam PF17131 Outer membrane lipoprotein-sorting protein 84 260 3.9E-37 T 05-07-2017 IPR033399 Putative outer membrane lipoprotein-sorting protein K08M4_RS21725 838ba074e115efaeb0f1759b7e61f7ef 266 Gene3D G3DSA:2.50.20.10 31 260 6.4E-58 T 05-07-2017 K08M4_RS21725 838ba074e115efaeb0f1759b7e61f7ef 266 PIRSF PIRSF028205 7 263 3.8E-98 T 05-07-2017 IPR011220 Uncharacterised conserved protein UCP028205 K08M4_RS03440 af7a87e43b827f6f397a14a49c64b1e8 105 Pfam PF12286 Protein of unknown function (DUF3622) 1 71 1.4E-34 T 05-07-2017 IPR022069 Protein of unknown function DUF3622 K08M4_RS15775 6f46a138cb6d840fedcee41bc9b0dd87 305 Pfam PF03466 LysR substrate binding domain 86 301 4.8E-10 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS15775 6f46a138cb6d840fedcee41bc9b0dd87 305 SUPERFAMILY SSF53850 86 299 1.71E-11 T 05-07-2017 K08M4_RS15775 6f46a138cb6d840fedcee41bc9b0dd87 305 Gene3D G3DSA:3.40.190.10 84 194 1.6E-9 T 05-07-2017 K08M4_RS15775 6f46a138cb6d840fedcee41bc9b0dd87 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 60 8.3E-19 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS15775 6f46a138cb6d840fedcee41bc9b0dd87 305 Gene3D G3DSA:1.10.10.10 4 83 1.1E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15775 6f46a138cb6d840fedcee41bc9b0dd87 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 2.2E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS15775 6f46a138cb6d840fedcee41bc9b0dd87 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 2.2E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS15775 6f46a138cb6d840fedcee41bc9b0dd87 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 2.2E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS15775 6f46a138cb6d840fedcee41bc9b0dd87 305 SUPERFAMILY SSF46785 4 106 2.08E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05605 f78c0fb15cdba540dc9abf9049e3888d 327 Gene3D G3DSA:3.40.50.1980 40 161 5.2E-16 T 05-07-2017 K08M4_RS05605 f78c0fb15cdba540dc9abf9049e3888d 327 Pfam PF01497 Periplasmic binding protein 63 299 5.6E-18 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 K08M4_RS05605 f78c0fb15cdba540dc9abf9049e3888d 327 Gene3D G3DSA:3.40.50.1980 162 321 2.5E-22 T 05-07-2017 K08M4_RS05605 f78c0fb15cdba540dc9abf9049e3888d 327 SUPERFAMILY SSF53807 37 312 1.73E-37 T 05-07-2017 K08M4_RS14260 c478b6bb8e5a71198c6973ff01e3ab22 297 Hamap MF_00117 33 kDa chaperonin [hslO]. 8 288 32.006 T 05-07-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 K08M4_RS14260 c478b6bb8e5a71198c6973ff01e3ab22 297 SUPERFAMILY SSF118352 228 287 2.22E-17 T 05-07-2017 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 K08M4_RS14260 c478b6bb8e5a71198c6973ff01e3ab22 297 Gene3D G3DSA:1.10.287.480 181 229 3.0E-25 T 05-07-2017 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain K08M4_RS14260 c478b6bb8e5a71198c6973ff01e3ab22 297 SUPERFAMILY SSF64397 9 236 1.96E-76 T 05-07-2017 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 K08M4_RS14260 c478b6bb8e5a71198c6973ff01e3ab22 297 Gene3D G3DSA:3.55.30.10 6 180 1.5E-66 T 05-07-2017 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 K08M4_RS14260 c478b6bb8e5a71198c6973ff01e3ab22 297 Gene3D G3DSA:3.90.1280.10 230 287 2.7E-21 T 05-07-2017 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 K08M4_RS14260 c478b6bb8e5a71198c6973ff01e3ab22 297 Pfam PF01430 Hsp33 protein 11 277 1.7E-79 T 05-07-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 K08M4_RS14260 c478b6bb8e5a71198c6973ff01e3ab22 297 PIRSF PIRSF005261 1 289 2.8E-71 T 05-07-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 K08M4_RS04675 cc454b00209ef2a0d7f864dcce89d8e1 331 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 150 3.5E-60 T 05-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS04675 cc454b00209ef2a0d7f864dcce89d8e1 331 Gene3D G3DSA:3.40.50.720 1 158 3.8E-77 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04675 cc454b00209ef2a0d7f864dcce89d8e1 331 Gene3D G3DSA:3.30.360.10 159 314 4.4E-83 T 05-07-2017 K08M4_RS04675 cc454b00209ef2a0d7f864dcce89d8e1 331 SUPERFAMILY SSF55347 149 312 1.04E-75 T 05-07-2017 K08M4_RS04675 cc454b00209ef2a0d7f864dcce89d8e1 331 SUPERFAMILY SSF51735 3 166 4.42E-66 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04675 cc454b00209ef2a0d7f864dcce89d8e1 331 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 155 312 3.9E-68 T 05-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS04675 cc454b00209ef2a0d7f864dcce89d8e1 331 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 148 155 - T 05-07-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS04675 cc454b00209ef2a0d7f864dcce89d8e1 331 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 5.2E-135 T 05-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS04675 cc454b00209ef2a0d7f864dcce89d8e1 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 1.7E-45 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS04675 cc454b00209ef2a0d7f864dcce89d8e1 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 1.7E-45 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS04675 cc454b00209ef2a0d7f864dcce89d8e1 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 144 162 1.7E-45 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS04675 cc454b00209ef2a0d7f864dcce89d8e1 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 171 187 1.7E-45 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS04675 cc454b00209ef2a0d7f864dcce89d8e1 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 1.7E-45 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS04675 cc454b00209ef2a0d7f864dcce89d8e1 331 SMART SM00846 3 150 1.8E-94 T 05-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS04675 cc454b00209ef2a0d7f864dcce89d8e1 331 PIRSF PIRSF000149 1 331 2.7E-133 T 05-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS13910 481763aa3f7f68dbfdb4bb56a3483e59 185 SUPERFAMILY SSF51182 1 181 5.43E-78 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS13910 481763aa3f7f68dbfdb4bb56a3483e59 185 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 179 4.8E-84 T 05-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 K08M4_RS13910 481763aa3f7f68dbfdb4bb56a3483e59 185 Gene3D G3DSA:2.60.120.10 1 182 1.1E-82 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS13910 481763aa3f7f68dbfdb4bb56a3483e59 185 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 171 7.0E-80 T 05-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 K08M4_RS13910 481763aa3f7f68dbfdb4bb56a3483e59 185 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 178 9.9E-75 T 05-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 K08M4_RS02405 08d1d4a8bec261761a33369b1ac99259 323 SUPERFAMILY SSF103025 9 235 3.14E-51 T 05-07-2017 K08M4_RS02405 08d1d4a8bec261761a33369b1ac99259 323 SUPERFAMILY SSF101790 237 321 8.5E-18 T 05-07-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain K08M4_RS02405 08d1d4a8bec261761a33369b1ac99259 323 Pfam PF01571 Aminomethyltransferase folate-binding domain 25 137 3.0E-5 T 05-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal K08M4_RS02405 08d1d4a8bec261761a33369b1ac99259 323 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 181 245 1.0E-23 T 05-07-2017 IPR017703 YgfZ/GcvT conserved site K08M4_RS02405 08d1d4a8bec261761a33369b1ac99259 323 Gene3D G3DSA:3.30.70.1400 29 114 2.9E-30 T 05-07-2017 K08M4_RS02405 08d1d4a8bec261761a33369b1ac99259 323 Hamap MF_01175 tRNA-modifying protein YgfZ [ygfZ]. 1 317 40.936 T 05-07-2017 IPR023758 tRNA-modifying protein YgfZ GO:0005542|GO:0009451 K08M4_RS08045 f8659302a704a78a0e126179a031eac4 323 PIRSF PIRSF017082 2 323 9.1E-84 T 05-07-2017 IPR005064 Bordetella uptake gene GO:0030288 K08M4_RS08045 f8659302a704a78a0e126179a031eac4 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 65 320 4.5E-27 T 05-07-2017 IPR005064 Bordetella uptake gene GO:0030288 K08M4_RS08045 f8659302a704a78a0e126179a031eac4 323 SUPERFAMILY SSF53850 104 289 8.14E-9 T 05-07-2017 K08M4_RS01380 4ac7dae05c9a2ee54dd3844b12bf298a 194 SUPERFAMILY SSF52218 12 184 1.38E-44 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS01380 4ac7dae05c9a2ee54dd3844b12bf298a 194 Gene3D G3DSA:3.40.50.360 13 182 3.7E-44 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS01380 4ac7dae05c9a2ee54dd3844b12bf298a 194 Hamap MF_01415 Glutathione-regulated potassium-efflux system ancillary protein KefG [kefG]. 8 189 47.044 T 05-07-2017 IPR023947 Glutathione-regulated potassium-efflux system ancillary protein KefG GO:0006813 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 K08M4_RS01380 4ac7dae05c9a2ee54dd3844b12bf298a 194 Pfam PF02525 Flavodoxin-like fold 13 179 8.4E-40 T 05-07-2017 IPR003680 Flavodoxin-like fold K08M4_RS01145 d7f5eb7e2946d2ebc85da5a02934b9fb 334 Gene3D G3DSA:1.10.260.40 2 60 3.0E-23 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS01145 d7f5eb7e2946d2ebc85da5a02934b9fb 334 Pfam PF13377 Periplasmic binding protein-like domain 168 329 3.5E-43 T 05-07-2017 K08M4_RS01145 d7f5eb7e2946d2ebc85da5a02934b9fb 334 SMART SM00354 1 71 2.2E-30 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS01145 d7f5eb7e2946d2ebc85da5a02934b9fb 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.5E-19 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS01145 d7f5eb7e2946d2ebc85da5a02934b9fb 334 Gene3D G3DSA:3.40.50.2300 61 167 1.2E-33 T 05-07-2017 K08M4_RS01145 d7f5eb7e2946d2ebc85da5a02934b9fb 334 SUPERFAMILY SSF47413 1 59 1.03E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS01145 d7f5eb7e2946d2ebc85da5a02934b9fb 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 05-07-2017 K08M4_RS01145 d7f5eb7e2946d2ebc85da5a02934b9fb 334 SUPERFAMILY SSF53822 60 332 2.16E-89 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS01145 d7f5eb7e2946d2ebc85da5a02934b9fb 334 Gene3D G3DSA:3.40.50.2300 168 331 1.2E-64 T 05-07-2017 K08M4_RS01060 5f3441ae2d8f43a912ff7a6b6ca6e05f 459 Pfam PF16527 Two-component sensor protein CpxA, periplasmic domain 36 166 4.5E-55 T 05-07-2017 IPR032404 Two-component sensor protein CpxA, periplasmic domain K08M4_RS01060 5f3441ae2d8f43a912ff7a6b6ca6e05f 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 411 1.0E-11 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS01060 5f3441ae2d8f43a912ff7a6b6ca6e05f 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 1.0E-11 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS01060 5f3441ae2d8f43a912ff7a6b6ca6e05f 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 1.0E-11 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS01060 5f3441ae2d8f43a912ff7a6b6ca6e05f 459 Gene3D G3DSA:1.10.287.130 232 289 1.6E-14 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS01060 5f3441ae2d8f43a912ff7a6b6ca6e05f 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 243 302 1.2E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS01060 5f3441ae2d8f43a912ff7a6b6ca6e05f 459 SMART SM00387 348 458 4.8E-24 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS01060 5f3441ae2d8f43a912ff7a6b6ca6e05f 459 SMART SM00388 242 304 3.0E-9 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS01060 5f3441ae2d8f43a912ff7a6b6ca6e05f 459 Gene3D G3DSA:3.30.565.10 290 457 5.2E-33 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS01060 5f3441ae2d8f43a912ff7a6b6ca6e05f 459 SUPERFAMILY SSF55874 294 456 3.27E-31 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS01060 5f3441ae2d8f43a912ff7a6b6ca6e05f 459 SUPERFAMILY SSF158472 189 240 2.22E-5 T 05-07-2017 K08M4_RS01060 5f3441ae2d8f43a912ff7a6b6ca6e05f 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 455 4.8E-15 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS01060 5f3441ae2d8f43a912ff7a6b6ca6e05f 459 SMART SM00304 188 241 2.9E-10 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS01060 5f3441ae2d8f43a912ff7a6b6ca6e05f 459 Pfam PF00672 HAMP domain 171 237 4.1E-13 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS01060 5f3441ae2d8f43a912ff7a6b6ca6e05f 459 SUPERFAMILY SSF47384 228 302 2.55E-13 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS17010 9ca69e5190ef014cc09e55c14b36bc10 589 SUPERFAMILY SSF52540 343 580 1.52E-77 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17010 9ca69e5190ef014cc09e55c14b36bc10 589 Pfam PF00005 ABC transporter 363 512 2.2E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS17010 9ca69e5190ef014cc09e55c14b36bc10 589 SUPERFAMILY SSF90123 11 324 1.44E-73 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS17010 9ca69e5190ef014cc09e55c14b36bc10 589 Gene3D G3DSA:3.40.50.300 346 575 1.1E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17010 9ca69e5190ef014cc09e55c14b36bc10 589 SMART SM00382 372 558 1.1E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS17010 9ca69e5190ef014cc09e55c14b36bc10 589 Pfam PF00664 ABC transporter transmembrane region 25 288 7.0E-53 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS17010 9ca69e5190ef014cc09e55c14b36bc10 589 Gene3D G3DSA:1.20.1560.10 11 324 1.5E-73 T 05-07-2017 K08M4_RS08760 29c27a809720294c5ee51944d0b94b3f 219 SUPERFAMILY SSF46894 119 217 1.16E-26 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS08760 29c27a809720294c5ee51944d0b94b3f 219 SUPERFAMILY SSF52172 1 118 1.85E-36 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS08760 29c27a809720294c5ee51944d0b94b3f 219 Pfam PF00072 Response regulator receiver domain 3 113 2.9E-24 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS08760 29c27a809720294c5ee51944d0b94b3f 219 Gene3D G3DSA:3.40.50.2300 1 120 8.4E-34 T 05-07-2017 K08M4_RS08760 29c27a809720294c5ee51944d0b94b3f 219 SMART SM00448 1 112 2.9E-34 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS08760 29c27a809720294c5ee51944d0b94b3f 219 SMART SM00862 145 216 7.5E-23 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS08760 29c27a809720294c5ee51944d0b94b3f 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 2.4E-22 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS08760 29c27a809720294c5ee51944d0b94b3f 219 Gene3D G3DSA:1.10.10.10 123 219 8.0E-29 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS11520 d247970aa2f5f6cca147caf0c720d2d0 452 SUPERFAMILY SSF103473 11 437 1.83E-33 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS11520 d247970aa2f5f6cca147caf0c720d2d0 452 Gene3D G3DSA:1.20.1250.20 259 437 4.0E-14 T 05-07-2017 K08M4_RS11520 d247970aa2f5f6cca147caf0c720d2d0 452 Gene3D G3DSA:1.20.1250.20 19 222 9.3E-17 T 05-07-2017 K08M4_RS11520 d247970aa2f5f6cca147caf0c720d2d0 452 Pfam PF07690 Major Facilitator Superfamily 25 398 3.3E-17 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS10110 ee3b5d910e8a26b9ddceed0e11aaff65 446 Pfam PF02056 Family 4 glycosyl hydrolase 8 188 4.3E-57 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 K08M4_RS10110 ee3b5d910e8a26b9ddceed0e11aaff65 446 Gene3D G3DSA:3.40.50.720 5 171 9.7E-65 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS10110 ee3b5d910e8a26b9ddceed0e11aaff65 446 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 143 173 - T 05-07-2017 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 K08M4_RS10110 ee3b5d910e8a26b9ddceed0e11aaff65 446 SUPERFAMILY SSF51735 6 171 4.4E-52 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS10110 ee3b5d910e8a26b9ddceed0e11aaff65 446 SUPERFAMILY SSF56327 174 439 6.72E-78 T 05-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 K08M4_RS10110 ee3b5d910e8a26b9ddceed0e11aaff65 446 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 198 413 3.4E-46 T 05-07-2017 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 K08M4_RS10110 ee3b5d910e8a26b9ddceed0e11aaff65 446 Gene3D G3DSA:3.90.110.10 172 437 1.1E-87 T 05-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 K08M4_RS10110 ee3b5d910e8a26b9ddceed0e11aaff65 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 143 160 4.2E-40 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 K08M4_RS10110 ee3b5d910e8a26b9ddceed0e11aaff65 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 194 206 4.2E-40 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 K08M4_RS10110 ee3b5d910e8a26b9ddceed0e11aaff65 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 100 113 4.2E-40 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 K08M4_RS10110 ee3b5d910e8a26b9ddceed0e11aaff65 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 168 179 4.2E-40 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 K08M4_RS10110 ee3b5d910e8a26b9ddceed0e11aaff65 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 8 23 4.2E-40 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 K08M4_RS10110 ee3b5d910e8a26b9ddceed0e11aaff65 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 79 95 4.2E-40 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 K08M4_RS10110 ee3b5d910e8a26b9ddceed0e11aaff65 446 PRINTS PR00732 Glycosyl hydrolase family 4 signature 114 134 4.2E-40 T 05-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 K08M4_RS18315 a74432bdb73012d807dcc57ef917f799 76 Pfam PF11661 Protein of unknown function (DUF2986) 1 43 1.1E-21 T 05-07-2017 IPR021677 Protein of unknown function DUF2986 K08M4_RS18160 a74432bdb73012d807dcc57ef917f799 76 Pfam PF11661 Protein of unknown function (DUF2986) 1 43 1.1E-21 T 05-07-2017 IPR021677 Protein of unknown function DUF2986 K08M4_RS12155 d2b6c4ae74437f1cfd492a49336344bc 98 PIRSF PIRSF003196 1 98 4.0E-38 T 05-07-2017 IPR013335 Trp repressor, bacterial GO:0006355 K08M4_RS12155 d2b6c4ae74437f1cfd492a49336344bc 98 ProDom PD012582 REPRESSOR TRANSCRIPTION TRP OPERON DNA-BINDING REGULATION HOMOLOG AROH FOR TRYPTOPHAN 4 81 6.0E-31 T 05-07-2017 IPR013335 Trp repressor, bacterial GO:0006355 K08M4_RS12155 d2b6c4ae74437f1cfd492a49336344bc 98 Gene3D G3DSA:1.10.1270.10 2 97 3.7E-38 T 05-07-2017 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 K08M4_RS12155 d2b6c4ae74437f1cfd492a49336344bc 98 SUPERFAMILY SSF48295 2 96 6.8E-30 T 05-07-2017 IPR010921 Trp repressor/replication initiator GO:0043565 K08M4_RS12155 d2b6c4ae74437f1cfd492a49336344bc 98 TIGRFAM TIGR01321 TrpR: trp operon repressor 6 86 2.2E-27 T 05-07-2017 IPR013335 Trp repressor, bacterial GO:0006355 K08M4_RS12155 d2b6c4ae74437f1cfd492a49336344bc 98 Hamap MF_00475 Trp operon repressor [trpR]. 6 98 21.182 T 05-07-2017 IPR013335 Trp repressor, bacterial GO:0006355 K08M4_RS12155 d2b6c4ae74437f1cfd492a49336344bc 98 Pfam PF01371 Trp repressor protein 8 93 4.7E-31 T 05-07-2017 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 K08M4_RS05185 3c04f02ff02f835f05edf73436c24258 400 Pfam PF01734 Patatin-like phospholipase 28 197 1.6E-13 T 05-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 K08M4_RS05185 3c04f02ff02f835f05edf73436c24258 400 SUPERFAMILY SSF52151 24 272 4.19E-30 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 K08M4_RS06195 0b04a0ee51a7702f0ea0d4cd9480edc2 732 Pfam PF05426 Alginate lyase 45 272 1.5E-15 T 05-07-2017 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 K08M4_RS06195 0b04a0ee51a7702f0ea0d4cd9480edc2 732 SUPERFAMILY SSF48230 44 289 5.13E-45 T 05-07-2017 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 K08M4_RS06195 0b04a0ee51a7702f0ea0d4cd9480edc2 732 Gene3D G3DSA:1.50.10.110 54 311 5.3E-34 T 05-07-2017 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 K08M4_RS06195 0b04a0ee51a7702f0ea0d4cd9480edc2 732 Pfam PF07940 Heparinase II/III-like protein 371 632 5.6E-23 T 05-07-2017 IPR012480 Heparinase II/III-like GO:0016829 K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 Gene3D G3DSA:2.40.30.10 210 307 2.1E-27 T 05-07-2017 K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 SUPERFAMILY SSF54980 402 516 1.25E-26 T 05-07-2017 IPR009022 Elongation factor G, III-V domain K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 155 2.3E-24 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 9 603 3.5E-290 T 05-07-2017 IPR006298 GTP-binding protein TypA GO:0005525 K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 SUPERFAMILY SSF52540 5 211 1.61E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 Gene3D G3DSA:3.30.70.870 308 403 5.9E-39 T 05-07-2017 K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 Pfam PF00679 Elongation factor G C-terminus 400 481 7.2E-22 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 SUPERFAMILY SSF50447 155 303 1.02E-32 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 Gene3D G3DSA:3.40.50.300 7 209 1.8E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 PRINTS PR00315 GTP-binding elongation factor signature 55 63 1.8E-14 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 PRINTS PR00315 GTP-binding elongation factor signature 75 85 1.8E-14 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 PRINTS PR00315 GTP-binding elongation factor signature 91 102 1.8E-14 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 PRINTS PR00315 GTP-binding elongation factor signature 127 136 1.8E-14 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 PRINTS PR00315 GTP-binding elongation factor signature 11 24 1.8E-14 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 Pfam PF03144 Elongation factor Tu domain 2 223 293 4.4E-10 T 05-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 05-07-2017 IPR031157 Tr-type G domain, conserved site K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 Gene3D G3DSA:2.40.50.250 487 581 9.7E-39 T 05-07-2017 K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 SUPERFAMILY SSF54980 306 391 7.55E-16 T 05-07-2017 IPR009022 Elongation factor G, III-V domain K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 Pfam PF00009 Elongation factor Tu GTP binding domain 8 198 2.9E-57 T 05-07-2017 K08M4_RS14300 fe6f5ec72bcf6b7b6c18075de793cdcd 610 Gene3D G3DSA:3.30.70.240 404 484 1.6E-32 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain K08M4_RS12260 a8610f8e4d11f1fbcd314a2597f268b4 97 SMART SM00418 15 93 9.6E-29 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS12260 a8610f8e4d11f1fbcd314a2597f268b4 97 SUPERFAMILY SSF46785 9 96 4.37E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS12260 a8610f8e4d11f1fbcd314a2597f268b4 97 Pfam PF01022 Bacterial regulatory protein, arsR family 23 68 3.9E-16 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS12260 a8610f8e4d11f1fbcd314a2597f268b4 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 17 32 8.1E-16 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS12260 a8610f8e4d11f1fbcd314a2597f268b4 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 47 8.1E-16 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS12260 a8610f8e4d11f1fbcd314a2597f268b4 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 8.1E-16 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS12260 a8610f8e4d11f1fbcd314a2597f268b4 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 8.1E-16 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS12260 a8610f8e4d11f1fbcd314a2597f268b4 97 Gene3D G3DSA:1.10.10.10 2 97 2.1E-37 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS07005 882594cb07bbed9abdcd481a3aaa6296 168 Gene3D G3DSA:3.40.50.1000 30 164 4.0E-26 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS07005 882594cb07bbed9abdcd481a3aaa6296 168 SUPERFAMILY SSF56784 9 164 1.59E-23 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS07005 882594cb07bbed9abdcd481a3aaa6296 168 Pfam PF13419 Haloacid dehalogenase-like hydrolase 34 138 2.5E-10 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS06120 bfbc00d36d69d0d178247dd8cbcb9118 117 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 05-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS06120 bfbc00d36d69d0d178247dd8cbcb9118 117 SUPERFAMILY SSF74731 2 115 5.62E-50 T 05-07-2017 K08M4_RS06120 bfbc00d36d69d0d178247dd8cbcb9118 117 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.1E-52 T 05-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS06120 bfbc00d36d69d0d178247dd8cbcb9118 117 Pfam PF00453 Ribosomal protein L20 3 108 3.9E-49 T 05-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS06120 bfbc00d36d69d0d178247dd8cbcb9118 117 Gene3D G3DSA:1.10.1900.20 55 116 1.4E-30 T 05-07-2017 K08M4_RS06120 bfbc00d36d69d0d178247dd8cbcb9118 117 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.654 T 05-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS06120 bfbc00d36d69d0d178247dd8cbcb9118 117 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.6E-42 T 05-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS06120 bfbc00d36d69d0d178247dd8cbcb9118 117 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.6E-42 T 05-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS06120 bfbc00d36d69d0d178247dd8cbcb9118 117 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.6E-42 T 05-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS06120 bfbc00d36d69d0d178247dd8cbcb9118 117 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 4.0E-22 T 05-07-2017 K08M4_RS18465 bca5d3ad4145e2a5694427ee1b7c6758 368 SUPERFAMILY SSF50331 236 359 5.95E-20 T 05-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal K08M4_RS18465 bca5d3ad4145e2a5694427ee1b7c6758 368 Gene3D G3DSA:3.40.50.300 17 233 2.4E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18465 bca5d3ad4145e2a5694427ee1b7c6758 368 Pfam PF03459 TOBE domain 293 360 3.6E-17 T 05-07-2017 IPR005116 Transport-associated OB, type 1 K08M4_RS18465 bca5d3ad4145e2a5694427ee1b7c6758 368 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 5 359 3.0E-139 T 05-07-2017 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 K08M4_RS18465 bca5d3ad4145e2a5694427ee1b7c6758 368 SMART SM00382 25 207 3.9E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS18465 bca5d3ad4145e2a5694427ee1b7c6758 368 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS18465 bca5d3ad4145e2a5694427ee1b7c6758 368 Pfam PF00005 ABC transporter 18 158 8.7E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS18465 bca5d3ad4145e2a5694427ee1b7c6758 368 Gene3D G3DSA:2.40.50.100 280 356 7.5E-19 T 05-07-2017 K08M4_RS18465 bca5d3ad4145e2a5694427ee1b7c6758 368 SUPERFAMILY SSF52540 12 237 2.77E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06560 b51066a43ed961a2c58f667c410a6b8c 211 Gene3D G3DSA:3.40.50.300 19 193 2.4E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06560 b51066a43ed961a2c58f667c410a6b8c 211 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 20 192 6.6E-56 T 05-07-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 K08M4_RS06560 b51066a43ed961a2c58f667c410a6b8c 211 PIRSF PIRSF006135 17 195 4.5E-52 T 05-07-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 K08M4_RS06560 b51066a43ed961a2c58f667c410a6b8c 211 SUPERFAMILY SSF52540 19 193 6.49E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16095 f5d7a3bbce9fc286475a1fa173fe85c7 145 Gene3D G3DSA:2.60.120.600 50 141 2.0E-8 T 05-07-2017 IPR010621 Domain of unknown function DUF1214 K08M4_RS16095 f5d7a3bbce9fc286475a1fa173fe85c7 145 Pfam PF06742 Protein of unknown function (DUF1214) 50 141 1.1E-9 T 05-07-2017 IPR010621 Domain of unknown function DUF1214 K08M4_RS16095 f5d7a3bbce9fc286475a1fa173fe85c7 145 SUPERFAMILY SSF160935 56 141 1.57E-8 T 05-07-2017 K08M4_RS01780 d858d3bc4c71b9bcd7a8e4f629382754 447 SUPERFAMILY SSF111283 14 447 2.22E-128 T 05-07-2017 K08M4_RS01780 d858d3bc4c71b9bcd7a8e4f629382754 447 Pfam PF01523 Putative modulator of DNA gyrase 32 324 1.8E-55 T 05-07-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 K08M4_RS03925 ee064f92ef0e6ea93c2bd1d83ef32d9f 232 SUPERFAMILY SSF89392 42 217 1.14E-17 T 05-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX K08M4_RS03925 ee064f92ef0e6ea93c2bd1d83ef32d9f 232 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 52 221 3.6E-7 T 05-07-2017 IPR004564 Outer membrane lipoprotein carrier protein LolA-like K08M4_RS03925 ee064f92ef0e6ea93c2bd1d83ef32d9f 232 Gene3D G3DSA:2.50.20.10 42 220 2.3E-13 T 05-07-2017 K08M4_RS01260 09c2c8f8d634da9edb5f1c650750d4e0 204 Pfam PF05137 Fimbrial assembly protein (PilN) 103 176 1.5E-12 T 05-07-2017 IPR007813 Fimbrial assembly PilN K08M4_RS01155 59645e4bf93aa6070c6e5e6cb1609442 72 PRINTS PR01249 Ribosomal protein L31 signature 32 47 7.3E-23 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01155 59645e4bf93aa6070c6e5e6cb1609442 72 PRINTS PR01249 Ribosomal protein L31 signature 2 19 7.3E-23 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01155 59645e4bf93aa6070c6e5e6cb1609442 72 PRINTS PR01249 Ribosomal protein L31 signature 47 65 7.3E-23 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01155 59645e4bf93aa6070c6e5e6cb1609442 72 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 67 1.7E-34 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01155 59645e4bf93aa6070c6e5e6cb1609442 72 SUPERFAMILY SSF143800 1 68 5.1E-27 T 05-07-2017 K08M4_RS01155 59645e4bf93aa6070c6e5e6cb1609442 72 Pfam PF01197 Ribosomal protein L31 1 66 3.6E-32 T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01155 59645e4bf93aa6070c6e5e6cb1609442 72 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 05-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01155 59645e4bf93aa6070c6e5e6cb1609442 72 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 31.27 T 05-07-2017 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS21235 3d4fc4e8f8634cbd5d88800322a41d42 804 SUPERFAMILY SSF74650 2 262 1.16E-30 T 05-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 K08M4_RS21235 3d4fc4e8f8634cbd5d88800322a41d42 804 Gene3D G3DSA:1.50.10.10 374 676 1.9E-6 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 K08M4_RS21235 3d4fc4e8f8634cbd5d88800322a41d42 804 SUPERFAMILY SSF48208 287 804 1.22E-102 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 K08M4_RS21235 3d4fc4e8f8634cbd5d88800322a41d42 804 Pfam PF06165 Glycosyltransferase family 36 22 273 1.9E-43 T 05-07-2017 IPR010383 Glycosyl hydrolase 94 K08M4_RS21235 3d4fc4e8f8634cbd5d88800322a41d42 804 Gene3D G3DSA:2.60.420.10 723 782 3.4E-10 T 05-07-2017 K08M4_RS21235 3d4fc4e8f8634cbd5d88800322a41d42 804 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 307 731 2.2E-133 T 05-07-2017 IPR033432 Glycosyl hydrolase 36, catalytic domain K08M4_RS21235 3d4fc4e8f8634cbd5d88800322a41d42 804 Gene3D G3DSA:2.70.98.40 2 336 1.2E-58 T 05-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 K08M4_RS07075 424f9d4b8dd201ec3e75df2a7891f7aa 162 Gene3D G3DSA:3.40.630.30 2 147 7.7E-34 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS07075 424f9d4b8dd201ec3e75df2a7891f7aa 162 Pfam PF00583 Acetyltransferase (GNAT) family 63 143 4.4E-11 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS07075 424f9d4b8dd201ec3e75df2a7891f7aa 162 SUPERFAMILY SSF55729 5 147 8.19E-24 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS07050 0f400cd774c02148d8e2cb7d32d13514 137 Gene3D G3DSA:3.90.1590.10 4 131 1.5E-30 T 05-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 K08M4_RS07050 0f400cd774c02148d8e2cb7d32d13514 137 SUPERFAMILY SSF51316 3 126 5.86E-36 T 05-07-2017 IPR011057 Mss4-like K08M4_RS07050 0f400cd774c02148d8e2cb7d32d13514 137 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 25 109 2.7E-13 T 05-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 K08M4_RS18595 7c8f6e1e156133fd21f529b9f4967c44 247 Pfam PF03746 LamB/YcsF family 5 243 4.5E-95 T 05-07-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF K08M4_RS18595 7c8f6e1e156133fd21f529b9f4967c44 247 SUPERFAMILY SSF88713 4 245 6.67E-92 T 05-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 K08M4_RS13440 94fdb22da3588932464fac5c59698025 401 Pfam PF01103 Surface antigen 184 318 3.7E-5 T 05-07-2017 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020 K08M4_RS13440 94fdb22da3588932464fac5c59698025 401 Gene3D G3DSA:2.40.160.50 189 388 3.4E-4 T 05-07-2017 K08M4_RS10915 72b0f7fbc749d94107ec36340f25f29c 169 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 85 97 - T 05-07-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 K08M4_RS10915 72b0f7fbc749d94107ec36340f25f29c 169 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 22 146 5.8E-49 T 05-07-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 K08M4_RS10915 72b0f7fbc749d94107ec36340f25f29c 169 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 23 143 1.1E-49 T 05-07-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 K08M4_RS10915 72b0f7fbc749d94107ec36340f25f29c 169 Gene3D G3DSA:2.70.70.10 17 165 3.2E-59 T 05-07-2017 K08M4_RS10915 72b0f7fbc749d94107ec36340f25f29c 169 SUPERFAMILY SSF51261 17 166 5.93E-55 T 05-07-2017 IPR011055 Duplicated hybrid motif K08M4_RS10485 b3db66fd72f89a13cca78f6486d87173 233 SUPERFAMILY SSF53067 111 219 2.46E-27 T 05-07-2017 K08M4_RS10485 b3db66fd72f89a13cca78f6486d87173 233 Gene3D G3DSA:3.30.420.40 4 133 1.8E-46 T 05-07-2017 K08M4_RS10485 b3db66fd72f89a13cca78f6486d87173 233 SUPERFAMILY SSF53067 4 103 1.38E-31 T 05-07-2017 K08M4_RS10485 b3db66fd72f89a13cca78f6486d87173 233 Pfam PF00814 Glycoprotease family 30 164 7.5E-33 T 05-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 K08M4_RS10485 b3db66fd72f89a13cca78f6486d87173 233 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 5 221 1.7E-68 T 05-07-2017 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 K08M4_RS01205 2d3f26401c3c07c2fc37910a9c7af0b6 262 Gene3D G3DSA:3.40.1160.10 5 259 3.2E-75 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS01205 2d3f26401c3c07c2fc37910a9c7af0b6 262 Pfam PF00696 Amino acid kinase family 8 237 2.5E-36 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS01205 2d3f26401c3c07c2fc37910a9c7af0b6 262 SUPERFAMILY SSF53633 4 261 1.83E-59 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS01205 2d3f26401c3c07c2fc37910a9c7af0b6 262 TIGRFAM TIGR00761 argB: acetylglutamate kinase 8 233 2.6E-64 T 05-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 K08M4_RS01205 2d3f26401c3c07c2fc37910a9c7af0b6 262 PIRSF PIRSF000728 1 262 6.5E-69 T 05-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 K08M4_RS01205 2d3f26401c3c07c2fc37910a9c7af0b6 262 Hamap MF_00082_B Acetylglutamate kinase [argB]. 4 261 26.556 T 05-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 K08M4_RS18300 f61b301c0531e88bbf78ebd69859757e 244 Pfam PF00005 ABC transporter 21 160 6.4E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS18300 f61b301c0531e88bbf78ebd69859757e 244 SMART SM00382 30 208 3.3E-7 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS18300 f61b301c0531e88bbf78ebd69859757e 244 SUPERFAMILY SSF52540 5 221 5.84E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18300 f61b301c0531e88bbf78ebd69859757e 244 Gene3D G3DSA:3.40.50.300 4 225 3.7E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18300 f61b301c0531e88bbf78ebd69859757e 244 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS08690 1b53f7f3e4e5b41843de77476487400d 435 Gene3D G3DSA:1.20.1600.10 15 418 2.6E-63 T 05-07-2017 K08M4_RS08690 1b53f7f3e4e5b41843de77476487400d 435 SUPERFAMILY SSF56954 22 430 7.32E-84 T 05-07-2017 K08M4_RS08690 1b53f7f3e4e5b41843de77476487400d 435 Pfam PF02321 Outer membrane efflux protein 231 415 5.7E-28 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS08690 1b53f7f3e4e5b41843de77476487400d 435 Pfam PF02321 Outer membrane efflux protein 23 211 5.0E-21 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS08690 1b53f7f3e4e5b41843de77476487400d 435 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 20 429 8.7E-114 T 05-07-2017 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 K08M4_RS00855 d36a97bf4180eb92608871e684ae72fe 197 SUPERFAMILY SSF52141 3 190 1.14E-58 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 K08M4_RS00855 d36a97bf4180eb92608871e684ae72fe 197 Gene3D G3DSA:3.40.470.10 3 190 1.7E-45 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 K08M4_RS00855 d36a97bf4180eb92608871e684ae72fe 197 SMART SM00987 26 183 2.5E-29 T 05-07-2017 K08M4_RS00855 d36a97bf4180eb92608871e684ae72fe 197 SMART SM00986 26 183 2.5E-29 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 K08M4_RS00855 d36a97bf4180eb92608871e684ae72fe 197 Pfam PF03167 Uracil DNA glycosylase superfamily 30 179 4.1E-25 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 K08M4_RS09515 7beb4877a47844075a167eaa110233e9 434 SUPERFAMILY SSF53613 338 417 8.57E-45 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS09515 7beb4877a47844075a167eaa110233e9 434 SUPERFAMILY SSF53613 31 305 8.57E-45 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS09515 7beb4877a47844075a167eaa110233e9 434 Gene3D G3DSA:3.30.1110.10 45 95 2.8E-5 T 05-07-2017 K08M4_RS09515 7beb4877a47844075a167eaa110233e9 434 Gene3D G3DSA:3.40.1190.20 96 298 1.9E-46 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS09515 7beb4877a47844075a167eaa110233e9 434 Gene3D G3DSA:3.40.1190.20 337 434 1.9E-46 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS09515 7beb4877a47844075a167eaa110233e9 434 Pfam PF00294 pfkB family carbohydrate kinase 74 293 3.6E-12 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB K08M4_RS09640 7beb4877a47844075a167eaa110233e9 434 SUPERFAMILY SSF53613 338 417 8.57E-45 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS09640 7beb4877a47844075a167eaa110233e9 434 SUPERFAMILY SSF53613 31 305 8.57E-45 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS09640 7beb4877a47844075a167eaa110233e9 434 Gene3D G3DSA:3.30.1110.10 45 95 2.8E-5 T 05-07-2017 K08M4_RS09640 7beb4877a47844075a167eaa110233e9 434 Gene3D G3DSA:3.40.1190.20 96 298 1.9E-46 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS09640 7beb4877a47844075a167eaa110233e9 434 Gene3D G3DSA:3.40.1190.20 337 434 1.9E-46 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS09640 7beb4877a47844075a167eaa110233e9 434 Pfam PF00294 pfkB family carbohydrate kinase 74 293 3.6E-12 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB K08M4_RS01775 def308f911afaf5df708d40a7cd3db0e 174 Gene3D G3DSA:1.10.60.30 104 170 5.8E-28 T 05-07-2017 IPR023153 PSPTO4464-like domain K08M4_RS01775 def308f911afaf5df708d40a7cd3db0e 174 PIRSF PIRSF016183 1 174 3.9E-71 T 05-07-2017 IPR006839 Ribosome-associated, YjgA K08M4_RS01775 def308f911afaf5df708d40a7cd3db0e 174 Gene3D G3DSA:1.10.60.30 28 102 6.6E-34 T 05-07-2017 IPR023153 PSPTO4464-like domain K08M4_RS01775 def308f911afaf5df708d40a7cd3db0e 174 SUPERFAMILY SSF158710 28 170 8.5E-52 T 05-07-2017 K08M4_RS01775 def308f911afaf5df708d40a7cd3db0e 174 Hamap MF_00765 UPF0307 protein YjgA [yjgA]. 10 172 22.835 T 05-07-2017 IPR006839 Ribosome-associated, YjgA K08M4_RS01775 def308f911afaf5df708d40a7cd3db0e 174 Pfam PF04751 Protein of unknown function (DUF615) 18 168 1.6E-55 T 05-07-2017 IPR006839 Ribosome-associated, YjgA K08M4_RS15055 f45b09ed313f63ec82f69e35cbfd4045 191 Gene3D G3DSA:2.30.30.60 115 166 8.4E-11 T 05-07-2017 K08M4_RS15055 f45b09ed313f63ec82f69e35cbfd4045 191 SUPERFAMILY SSF50182 100 166 1.57E-12 T 05-07-2017 IPR010920 LSM domain K08M4_RS15055 f45b09ed313f63ec82f69e35cbfd4045 191 Pfam PF00924 Mechanosensitive ion channel 58 163 3.9E-12 T 05-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 K08M4_RS16180 9b635a7d73349261e3406b45f4a25013 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 96 2.2E-5 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 K08M4_RS16180 9b635a7d73349261e3406b45f4a25013 328 SMART SM00829 16 326 5.0E-6 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 K08M4_RS16180 9b635a7d73349261e3406b45f4a25013 328 SUPERFAMILY SSF51735 122 282 3.18E-19 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS16180 9b635a7d73349261e3406b45f4a25013 328 Pfam PF13602 Zinc-binding dehydrogenase 211 326 1.8E-8 T 05-07-2017 K08M4_RS16180 9b635a7d73349261e3406b45f4a25013 328 Gene3D G3DSA:3.90.180.10 8 95 1.4E-11 T 05-07-2017 IPR011032 GroES-like K08M4_RS16180 9b635a7d73349261e3406b45f4a25013 328 Gene3D G3DSA:3.40.50.720 128 287 7.3E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS16180 9b635a7d73349261e3406b45f4a25013 328 SUPERFAMILY SSF50129 16 151 1.08E-22 T 05-07-2017 IPR011032 GroES-like K08M4_RS14035 967ad286e3cf4747f7d55ad8fedb3efe 326 TIGRFAM TIGR02207 lipid_A_htrB: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase 20 318 2.6E-125 T 05-07-2017 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 K08M4_RS14035 967ad286e3cf4747f7d55ad8fedb3efe 326 PIRSF PIRSF026649 17 322 3.5E-81 T 05-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 K08M4_RS14035 967ad286e3cf4747f7d55ad8fedb3efe 326 Hamap MF_01942 Lipid A biosynthesis lauroyltransferase [lpxL]. 18 325 44.676 T 05-07-2017 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 K08M4_RS14035 967ad286e3cf4747f7d55ad8fedb3efe 326 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 20 313 1.4E-72 T 05-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 K08M4_RS13735 2b57edb6a2d5447ad2acc0604a4151ea 159 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 73 152 1.7E-36 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 K08M4_RS13735 2b57edb6a2d5447ad2acc0604a4151ea 159 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 74 153 3.5E-31 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 K08M4_RS13735 2b57edb6a2d5447ad2acc0604a4151ea 159 Gene3D G3DSA:1.10.10.10 71 154 3.1E-34 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS13735 2b57edb6a2d5447ad2acc0604a4151ea 159 SUPERFAMILY SSF46767 72 153 2.35E-31 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 K08M4_RS13735 2b57edb6a2d5447ad2acc0604a4151ea 159 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 5 69 1.8E-6 T 05-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 K08M4_RS13735 2b57edb6a2d5447ad2acc0604a4151ea 159 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 5 155 36.176 T 05-07-2017 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 K08M4_RS13735 2b57edb6a2d5447ad2acc0604a4151ea 159 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 123 129 - T 05-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 K08M4_RS13735 2b57edb6a2d5447ad2acc0604a4151ea 159 SUPERFAMILY SSF53155 5 78 1.31E-17 T 05-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 K08M4_RS08540 749a64a88ce8ee295f6cf06f24864719 467 Pfam PF00155 Aminotransferase class I and II 142 442 1.1E-33 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS08540 749a64a88ce8ee295f6cf06f24864719 467 Gene3D G3DSA:3.40.640.10 141 342 3.1E-69 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS08540 749a64a88ce8ee295f6cf06f24864719 467 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 5.2E-13 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS08540 749a64a88ce8ee295f6cf06f24864719 467 Gene3D G3DSA:1.10.10.10 2 69 5.0E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS08540 749a64a88ce8ee295f6cf06f24864719 467 SUPERFAMILY SSF46785 2 69 3.22E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS08540 749a64a88ce8ee295f6cf06f24864719 467 SMART SM00345 7 66 1.5E-12 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS08540 749a64a88ce8ee295f6cf06f24864719 467 SUPERFAMILY SSF53383 95 462 2.42E-92 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS08540 749a64a88ce8ee295f6cf06f24864719 467 Gene3D G3DSA:3.90.1150.10 343 445 3.9E-6 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS21800 3f69632692102c59a116a146d05bec6f 667 Pfam PF00501 AMP-binding enzyme 113 542 4.2E-43 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 K08M4_RS21800 3f69632692102c59a116a146d05bec6f 667 SUPERFAMILY SSF56801 36 661 1.44E-119 T 05-07-2017 K08M4_RS21800 3f69632692102c59a116a146d05bec6f 667 Gene3D G3DSA:3.40.50.980 295 448 1.5E-15 T 05-07-2017 K08M4_RS21800 3f69632692102c59a116a146d05bec6f 667 ProSitePatterns PS00455 Putative AMP-binding domain signature. 288 299 - T 05-07-2017 IPR020845 AMP-binding, conserved site K08M4_RS21800 3f69632692102c59a116a146d05bec6f 667 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 4 659 3.0E-233 T 05-07-2017 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 K08M4_RS21800 3f69632692102c59a116a146d05bec6f 667 Gene3D G3DSA:3.40.50.980 111 294 4.4E-27 T 05-07-2017 K08M4_RS21800 3f69632692102c59a116a146d05bec6f 667 Gene3D G3DSA:3.30.300.30 544 647 2.2E-15 T 05-07-2017 K08M4_RS14170 496d6750effe90bc6c8c138a76f25896 258 Gene3D G3DSA:3.40.50.1820 4 257 2.6E-53 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS14170 496d6750effe90bc6c8c138a76f25896 258 Pfam PF00561 alpha/beta hydrolase fold 16 244 9.2E-23 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS14170 496d6750effe90bc6c8c138a76f25896 258 Hamap MF_01260 Pimeloyl-[acyl-carrier protein] methyl ester esterase [bioH]. 5 257 45.553 T 05-07-2017 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 K08M4_RS14170 496d6750effe90bc6c8c138a76f25896 258 TIGRFAM TIGR01738 bioH: pimelyl-[acyl-carrier protein] methyl ester esterase 11 255 1.5E-106 T 05-07-2017 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 K08M4_RS14170 496d6750effe90bc6c8c138a76f25896 258 SUPERFAMILY SSF53474 4 255 4.26E-52 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS14415 1a618fa790dd7621ec56b24cfdb92379 259 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 166 180 - T 05-07-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 K08M4_RS14415 1a618fa790dd7621ec56b24cfdb92379 259 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 33 258 1.1E-83 T 05-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 K08M4_RS14415 1a618fa790dd7621ec56b24cfdb92379 259 Pfam PF01209 ubiE/COQ5 methyltransferase family 26 258 1.1E-101 T 05-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 K08M4_RS14415 1a618fa790dd7621ec56b24cfdb92379 259 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 24 258 38.247 T 05-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 K08M4_RS14415 1a618fa790dd7621ec56b24cfdb92379 259 Gene3D G3DSA:3.40.50.150 32 255 2.6E-60 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS14415 1a618fa790dd7621ec56b24cfdb92379 259 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 44 59 - T 05-07-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 K08M4_RS14415 1a618fa790dd7621ec56b24cfdb92379 259 SUPERFAMILY SSF53335 27 257 1.18E-52 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 Pfam PF00175 Oxidoreductase NAD-binding domain 278 386 4.0E-17 T 05-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 40 116 1.6E-10 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 SUPERFAMILY SSF52343 259 403 8.77E-36 T 05-07-2017 K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 Hamap MF_00430 Na(+)-translocating NADH-quinone reductase subunit F [nqrF]. 2 408 61.238 T 05-07-2017 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 243 252 8.2E-6 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 210 217 8.2E-6 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 374 382 8.2E-6 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 277 296 8.2E-6 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 Gene3D G3DSA:3.10.20.30 36 121 5.5E-20 T 05-07-2017 IPR012675 Beta-grasp domain K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 SUPERFAMILY SSF63380 106 273 2.17E-35 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 SUPERFAMILY SSF54292 40 123 9.42E-21 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 Gene3D G3DSA:3.40.50.80 270 407 5.2E-40 T 05-07-2017 K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 Gene3D G3DSA:2.40.30.10 125 265 1.3E-59 T 05-07-2017 K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 PIRSF PIRSF000044 1 408 5.6E-215 T 05-07-2017 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 TIGRFAM TIGR01941 nqrF: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit 4 408 1.5E-221 T 05-07-2017 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 K08M4_RS11470 39ef8d473df31f25d5bde4091afadfad 408 Pfam PF00970 Oxidoreductase FAD-binding domain 203 267 1.4E-9 T 05-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 K08M4_RS17830 b452feb605a35ba0e623256396dcb916 153 SUPERFAMILY SSF48695 52 151 2.24E-41 T 05-07-2017 IPR011031 Multihaem cytochrome K08M4_RS17830 b452feb605a35ba0e623256396dcb916 153 Gene3D G3DSA:4.10.1020.10 68 134 3.3E-32 T 05-07-2017 IPR027406 Periplasmic nitrate reductase NapB subunit, heme binding domain K08M4_RS17830 b452feb605a35ba0e623256396dcb916 153 Pfam PF03892 Nitrate reductase cytochrome c-type subunit (NapB) 34 148 5.9E-49 T 05-07-2017 IPR005591 Nitrate reductase cytochrome c-type subunit NapB K08M4_RS09850 8d7931ade6f593c29bd8bbc3881df4dd 181 Gene3D G3DSA:3.40.630.30 2 177 3.8E-45 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS09850 8d7931ade6f593c29bd8bbc3881df4dd 181 Pfam PF13302 Acetyltransferase (GNAT) domain 12 153 2.4E-21 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS09850 8d7931ade6f593c29bd8bbc3881df4dd 181 SUPERFAMILY SSF55729 3 177 2.16E-44 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS18740 83d149986d4e0124cbf710ae1b6c980c 571 Pfam PF02080 TrkA-C domain 223 288 8.8E-8 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS18740 83d149986d4e0124cbf710ae1b6c980c 571 Gene3D G3DSA:3.30.70.1450 222 289 2.2E-7 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS18740 83d149986d4e0124cbf710ae1b6c980c 571 Gene3D G3DSA:3.30.70.1450 310 379 2.7E-4 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS18740 83d149986d4e0124cbf710ae1b6c980c 571 SUPERFAMILY SSF116726 309 379 3.79E-7 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS18740 83d149986d4e0124cbf710ae1b6c980c 571 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 397 548 2.4E-23 T 05-07-2017 IPR006512 YidE/YbjL duplication K08M4_RS18740 83d149986d4e0124cbf710ae1b6c980c 571 SUPERFAMILY SSF116726 222 287 3.4E-8 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS18740 83d149986d4e0124cbf710ae1b6c980c 571 Pfam PF06826 Predicted Permease Membrane Region 15 180 3.7E-30 T 05-07-2017 IPR006512 YidE/YbjL duplication K08M4_RS18740 83d149986d4e0124cbf710ae1b6c980c 571 Pfam PF06826 Predicted Permease Membrane Region 393 562 5.6E-31 T 05-07-2017 IPR006512 YidE/YbjL duplication K08M4_RS18740 83d149986d4e0124cbf710ae1b6c980c 571 TIGRFAM TIGR03802 Asp_Ala_antiprt: aspartate-alanine antiporter 2 564 3.5E-201 T 05-07-2017 IPR022457 Aspartate-alanine antiporter GO:0005215|GO:0016020 K08M4_RS21425 7f8fded8397d2d19e21b287d90489586 279 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 177 221 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 K08M4_RS21425 7f8fded8397d2d19e21b287d90489586 279 SUPERFAMILY SSF46689 228 276 6.27E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS21425 7f8fded8397d2d19e21b287d90489586 279 Gene3D G3DSA:1.10.10.60 174 230 4.4E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS21425 7f8fded8397d2d19e21b287d90489586 279 Pfam PF12852 Cupin 2 161 2.7E-22 T 05-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain K08M4_RS21425 7f8fded8397d2d19e21b287d90489586 279 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 229 270 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 K08M4_RS21425 7f8fded8397d2d19e21b287d90489586 279 SUPERFAMILY SSF46689 175 226 1.7E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS21425 7f8fded8397d2d19e21b287d90489586 279 Pfam PF12833 Helix-turn-helix domain 199 275 2.2E-17 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS21425 7f8fded8397d2d19e21b287d90489586 279 Gene3D G3DSA:1.10.10.60 233 276 9.3E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS21425 7f8fded8397d2d19e21b287d90489586 279 SMART SM00342 192 274 4.6E-20 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS02235 ceaaba147b6093bc7d65136c7194f7ce 280 Pfam PF06180 Cobalt chelatase (CbiK) 12 227 4.2E-20 T 05-07-2017 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 K08M4_RS02235 ceaaba147b6093bc7d65136c7194f7ce 280 SUPERFAMILY SSF53800 11 268 1.42E-41 T 05-07-2017 K08M4_RS02235 ceaaba147b6093bc7d65136c7194f7ce 280 Gene3D G3DSA:3.40.50.1400 140 230 2.0E-7 T 05-07-2017 K08M4_RS02235 ceaaba147b6093bc7d65136c7194f7ce 280 Gene3D G3DSA:3.40.50.1400 7 139 2.5E-21 T 05-07-2017 K08M4_RS01085 dba570812fd2a4756294f27db9276aa1 256 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 241 7.6E-79 T 05-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS01085 dba570812fd2a4756294f27db9276aa1 256 Gene3D G3DSA:3.20.20.70 1 253 7.4E-97 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS01085 dba570812fd2a4756294f27db9276aa1 256 ProSitePatterns PS00171 Triosephosphate isomerase active site. 167 177 - T 05-07-2017 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS01085 dba570812fd2a4756294f27db9276aa1 256 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 251 39.065 T 05-07-2017 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS01085 dba570812fd2a4756294f27db9276aa1 256 SUPERFAMILY SSF51351 2 251 1.3E-87 T 05-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS01085 dba570812fd2a4756294f27db9276aa1 256 Pfam PF00121 Triosephosphate isomerase 5 247 4.9E-85 T 05-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 K08M4_RS00090 3f83f6218b9e3bbc2711736a13a95b1c 485 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 84 468 3.3E-118 T 05-07-2017 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 K08M4_RS00090 3f83f6218b9e3bbc2711736a13a95b1c 485 PIRSF PIRSF006247 1 485 4.0E-177 T 05-07-2017 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 K08M4_RS00090 3f83f6218b9e3bbc2711736a13a95b1c 485 Pfam PF02386 Cation transport protein 39 477 3.3E-91 T 05-07-2017 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 K08M4_RS19365 900f7fac7ddc366b3328b5d4149f693f 245 Pfam PF12525 Protein of unknown function (DUF3726) 3 80 2.7E-31 T 05-07-2017 IPR022201 Protein of unknown function DUF3726 K08M4_RS20395 5f0401aa9b9e862b17aae597210835bc 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 389 5.6E-9 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS20395 5f0401aa9b9e862b17aae597210835bc 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 433 5.6E-9 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS20395 5f0401aa9b9e862b17aae597210835bc 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 375 5.6E-9 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS20395 5f0401aa9b9e862b17aae597210835bc 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 414 5.6E-9 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS20395 5f0401aa9b9e862b17aae597210835bc 436 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 435 4.3E-16 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS20395 5f0401aa9b9e862b17aae597210835bc 436 SMART SM00387 326 436 1.4E-22 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS20395 5f0401aa9b9e862b17aae597210835bc 436 SMART SM00388 218 282 3.5E-5 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS20395 5f0401aa9b9e862b17aae597210835bc 436 Gene3D G3DSA:3.30.565.10 307 434 9.3E-27 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS20395 5f0401aa9b9e862b17aae597210835bc 436 Gene3D G3DSA:1.10.287.130 208 278 4.1E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS20395 5f0401aa9b9e862b17aae597210835bc 436 SUPERFAMILY SSF55874 285 434 7.99E-28 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS20395 5f0401aa9b9e862b17aae597210835bc 436 Pfam PF00512 His Kinase A (phospho-acceptor) domain 222 279 2.3E-8 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS20395 5f0401aa9b9e862b17aae597210835bc 436 SUPERFAMILY SSF47384 201 280 4.71E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS11220 cee126e802530af31eea990e76f867d7 243 Hamap MF_01220_B Uridylate kinase [pyrH]. 7 240 43.624 T 05-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 K08M4_RS11220 cee126e802530af31eea990e76f867d7 243 Gene3D G3DSA:3.40.1160.10 2 240 2.4E-86 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS11220 cee126e802530af31eea990e76f867d7 243 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 9 240 1.9E-102 T 05-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 K08M4_RS11220 cee126e802530af31eea990e76f867d7 243 PIRSF PIRSF005650 4 243 1.5E-88 T 05-07-2017 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 K08M4_RS11220 cee126e802530af31eea990e76f867d7 243 Pfam PF00696 Amino acid kinase family 11 219 2.4E-26 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS11220 cee126e802530af31eea990e76f867d7 243 SUPERFAMILY SSF53633 7 240 1.83E-71 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS17845 33d66af1e8e5b0e75c55c8d9f20ff749 159 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 67 78 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS17845 33d66af1e8e5b0e75c55c8d9f20ff749 159 TIGRFAM TIGR00402 napF: ferredoxin-type protein NapF 15 154 2.0E-43 T 05-07-2017 IPR004496 Ferredoxin-type protein NapF GO:0005506|GO:0009055 K08M4_RS17845 33d66af1e8e5b0e75c55c8d9f20ff749 159 Gene3D G3DSA:3.30.70.20 68 111 5.3E-8 T 05-07-2017 K08M4_RS17845 33d66af1e8e5b0e75c55c8d9f20ff749 159 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 35 46 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS17845 33d66af1e8e5b0e75c55c8d9f20ff749 159 SUPERFAMILY SSF54862 30 156 4.19E-19 T 05-07-2017 K08M4_RS17845 33d66af1e8e5b0e75c55c8d9f20ff749 159 Pfam PF00037 4Fe-4S binding domain 133 154 2.4E-7 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain K08M4_RS17845 33d66af1e8e5b0e75c55c8d9f20ff749 159 Pfam PF13187 4Fe-4S dicluster domain 34 79 3.5E-7 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain K08M4_RS17845 33d66af1e8e5b0e75c55c8d9f20ff749 159 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 139 150 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS17845 33d66af1e8e5b0e75c55c8d9f20ff749 159 Gene3D G3DSA:3.30.70.20 32 67 5.2E-11 T 05-07-2017 K08M4_RS17845 33d66af1e8e5b0e75c55c8d9f20ff749 159 Gene3D G3DSA:3.30.70.20 112 155 1.6E-9 T 05-07-2017 K08M4_RS06240 e76754012f750c4ee832a12ada619698 244 SUPERFAMILY SSF56935 70 244 9.16E-7 T 05-07-2017 K08M4_RS06240 e76754012f750c4ee832a12ada619698 244 Gene3D G3DSA:2.40.230.30 23 244 1.0E-65 T 05-07-2017 K08M4_RS06240 e76754012f750c4ee832a12ada619698 244 Pfam PF06178 Oligogalacturonate-specific porin protein (KdgM) 18 244 1.2E-35 T 05-07-2017 IPR009331 Oligogalacturonate-specific porin K08M4_RS11725 e4411fa4633276489f3307c32cbf99c3 102 Pfam PF03658 RnfH family Ubiquitin 8 90 2.2E-32 T 05-07-2017 IPR005346 RnfH protein K08M4_RS11725 e4411fa4633276489f3307c32cbf99c3 102 Gene3D G3DSA:3.10.20.280 2 92 3.3E-36 T 05-07-2017 IPR005346 RnfH protein K08M4_RS11725 e4411fa4633276489f3307c32cbf99c3 102 Hamap MF_00460 Protein RnfH [rnfH]. 8 98 23.626 T 05-07-2017 IPR005346 RnfH protein K08M4_RS11725 e4411fa4633276489f3307c32cbf99c3 102 SUPERFAMILY SSF54285 6 82 2.35E-24 T 05-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp K08M4_RS07280 25686c4da628b32586591329073bc0fd 110 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 5 108 7.3E-42 T 05-07-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 K08M4_RS07280 25686c4da628b32586591329073bc0fd 110 SUPERFAMILY SSF103481 10 108 1.44E-8 T 05-07-2017 K08M4_RS07280 25686c4da628b32586591329073bc0fd 110 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 108 25.369 T 05-07-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 K08M4_RS09030 0f9e7772dc7b34215a63536015d164bd 462 PIRSF PIRSF028099 6 462 4.3E-182 T 05-07-2017 IPR010538 Di-haem oxidoreductase, putative peroxidase K08M4_RS09030 0f9e7772dc7b34215a63536015d164bd 462 Gene3D G3DSA:1.10.760.10 325 462 6.1E-16 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS09030 0f9e7772dc7b34215a63536015d164bd 462 Pfam PF06537 Di-haem oxidoreductase, putative peroxidase 21 462 3.7E-143 T 05-07-2017 IPR010538 Di-haem oxidoreductase, putative peroxidase K08M4_RS09030 0f9e7772dc7b34215a63536015d164bd 462 SUPERFAMILY SSF46626 321 462 4.03E-23 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS12785 e9c6b6fa52d22cb8bf907fe60b235132 438 Pfam PF01743 Poly A polymerase head domain 32 150 3.9E-17 T 05-07-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 K08M4_RS12785 e9c6b6fa52d22cb8bf907fe60b235132 438 PIRSF PIRSF000813 29 436 6.5E-197 T 05-07-2017 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 K08M4_RS12785 e9c6b6fa52d22cb8bf907fe60b235132 438 Hamap MF_01262 CCA-adding enzyme [cca]. 29 429 42.859 T 05-07-2017 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 K08M4_RS12785 e9c6b6fa52d22cb8bf907fe60b235132 438 Gene3D G3DSA:3.30.460.10 25 149 5.9E-31 T 05-07-2017 K08M4_RS12785 e9c6b6fa52d22cb8bf907fe60b235132 438 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 177 240 9.1E-13 T 05-07-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 K08M4_RS12785 e9c6b6fa52d22cb8bf907fe60b235132 438 Pfam PF01966 HD domain 257 365 9.2E-9 T 05-07-2017 IPR006674 HD domain K08M4_RS12785 e9c6b6fa52d22cb8bf907fe60b235132 438 Gene3D G3DSA:1.10.3090.10 150 387 1.1E-55 T 05-07-2017 K08M4_RS12785 e9c6b6fa52d22cb8bf907fe60b235132 438 Hamap MF_01261 Multifunctional CCA protein [cca]. 29 435 52.064 T 05-07-2017 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 K08M4_RS12785 e9c6b6fa52d22cb8bf907fe60b235132 438 SUPERFAMILY SSF81301 23 147 3.92E-31 T 05-07-2017 K08M4_RS12785 e9c6b6fa52d22cb8bf907fe60b235132 438 SUPERFAMILY SSF81891 148 432 1.44E-54 T 05-07-2017 K08M4_RS07375 4c3f583855dd962b5c219b28d0bcfb70 330 Gene3D G3DSA:3.40.190.10 20 109 3.4E-24 T 05-07-2017 K08M4_RS07375 4c3f583855dd962b5c219b28d0bcfb70 330 Gene3D G3DSA:3.40.190.10 262 320 3.4E-24 T 05-07-2017 K08M4_RS07375 4c3f583855dd962b5c219b28d0bcfb70 330 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 26 309 2.8E-61 T 05-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 K08M4_RS07375 4c3f583855dd962b5c219b28d0bcfb70 330 Gene3D G3DSA:3.40.190.100 112 261 1.3E-30 T 05-07-2017 K08M4_RS07375 4c3f583855dd962b5c219b28d0bcfb70 330 SUPERFAMILY SSF53850 20 325 1.27E-67 T 05-07-2017 K08M4_RS14870 cab3b5263c25ab52d9c8f939128b1488 94 Pfam PF13710 ACT domain 12 73 9.3E-21 T 05-07-2017 K08M4_RS14870 cab3b5263c25ab52d9c8f939128b1488 94 Gene3D G3DSA:3.30.70.260 1 76 3.0E-11 T 05-07-2017 K08M4_RS14870 cab3b5263c25ab52d9c8f939128b1488 94 SUPERFAMILY SSF55021 3 75 1.97E-9 T 05-07-2017 K08M4_RS18270 fe8282194d99b043a6ec6655daccdae6 209 Pfam PF16357 Putative PepSY_TM-like 11 209 2.2E-59 T 05-07-2017 IPR032307 Putative PepSY TM-like protein K08M4_RS11785 68729bb4d08d9ea954c61fc3daab9759 197 Pfam PF01184 GPR1/FUN34/yaaH family 3 177 3.7E-36 T 05-07-2017 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 K08M4_RS11785 68729bb4d08d9ea954c61fc3daab9759 197 ProSitePatterns PS01114 GPR1/FUN34/yaaH family signature. 7 16 - T 05-07-2017 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 K08M4_RS11200 d41c7cc6f0b18bca4632235602e4b652 280 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 238 264 - T 05-07-2017 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 K08M4_RS11200 d41c7cc6f0b18bca4632235602e4b652 280 Pfam PF01148 Cytidylyltransferase family 2 278 1.3E-70 T 05-07-2017 K08M4_RS17075 e6fef623b082a4edc01a72265dc2d2ac 442 Gene3D G3DSA:1.20.1600.10 42 430 7.2E-59 T 05-07-2017 K08M4_RS17075 e6fef623b082a4edc01a72265dc2d2ac 442 SUPERFAMILY SSF56954 21 429 3.4E-73 T 05-07-2017 K08M4_RS17075 e6fef623b082a4edc01a72265dc2d2ac 442 Pfam PF02321 Outer membrane efflux protein 247 425 1.3E-26 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS17075 e6fef623b082a4edc01a72265dc2d2ac 442 Pfam PF02321 Outer membrane efflux protein 46 222 2.7E-24 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS14880 77a456893d926569bd6c4c18a6e2e393 613 Pfam PF00920 Dehydratase family 34 604 6.2E-216 T 05-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 K08M4_RS14880 77a456893d926569bd6c4c18a6e2e393 613 SUPERFAMILY SSF52016 421 608 1.41E-59 T 05-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel K08M4_RS14880 77a456893d926569bd6c4c18a6e2e393 613 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 607 1.5E-261 T 05-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 K08M4_RS14880 77a456893d926569bd6c4c18a6e2e393 613 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 05-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 K08M4_RS14880 77a456893d926569bd6c4c18a6e2e393 613 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 509 520 - T 05-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 K08M4_RS14880 77a456893d926569bd6c4c18a6e2e393 613 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 607 44.708 T 05-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 K08M4_RS14880 77a456893d926569bd6c4c18a6e2e393 613 SUPERFAMILY SSF143975 4 420 2.48E-134 T 05-07-2017 K08M4_RS05115 b7940901ed9c2c8aafd79d9ec3675f29 307 SUPERFAMILY SSF55048 130 197 7.46E-18 T 05-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 K08M4_RS05115 b7940901ed9c2c8aafd79d9ec3675f29 307 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 291 2.3E-125 T 05-07-2017 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 K08M4_RS05115 b7940901ed9c2c8aafd79d9ec3675f29 307 PIRSF PIRSF000446 1 307 8.7E-135 T 05-07-2017 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 K08M4_RS05115 b7940901ed9c2c8aafd79d9ec3675f29 307 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 307 7.6E-39 T 05-07-2017 IPR020801 Polyketide synthase, acyl transferase domain K08M4_RS05115 b7940901ed9c2c8aafd79d9ec3675f29 307 Pfam PF00698 Acyl transferase domain 7 291 1.3E-34 T 05-07-2017 IPR014043 Acyl transferase K08M4_RS05115 b7940901ed9c2c8aafd79d9ec3675f29 307 Gene3D G3DSA:3.30.70.250 125 196 2.3E-32 T 05-07-2017 K08M4_RS05115 b7940901ed9c2c8aafd79d9ec3675f29 307 SUPERFAMILY SSF52151 190 305 1.54E-80 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 K08M4_RS05115 b7940901ed9c2c8aafd79d9ec3675f29 307 SUPERFAMILY SSF52151 4 122 1.54E-80 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 K08M4_RS05115 b7940901ed9c2c8aafd79d9ec3675f29 307 Gene3D G3DSA:3.40.366.10 197 301 3.0E-69 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 K08M4_RS05115 b7940901ed9c2c8aafd79d9ec3675f29 307 Gene3D G3DSA:3.40.366.10 2 122 3.0E-69 T 05-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 K08M4_RS12740 b2ee171b20c9f3fab5b72d19ba892ea0 949 Pfam PF08335 GlnD PII-uridylyltransferase 302 441 2.6E-44 T 05-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 K08M4_RS12740 b2ee171b20c9f3fab5b72d19ba892ea0 949 Pfam PF08335 GlnD PII-uridylyltransferase 832 915 8.3E-7 T 05-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 K08M4_RS12740 b2ee171b20c9f3fab5b72d19ba892ea0 949 SUPERFAMILY SSF81301 26 291 4.16E-87 T 05-07-2017 K08M4_RS12740 b2ee171b20c9f3fab5b72d19ba892ea0 949 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 32 949 19.179 T 05-07-2017 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 K08M4_RS12740 b2ee171b20c9f3fab5b72d19ba892ea0 949 SUPERFAMILY SSF81301 529 818 2.85E-85 T 05-07-2017 K08M4_RS12740 b2ee171b20c9f3fab5b72d19ba892ea0 949 SUPERFAMILY SSF81593 820 947 4.47E-30 T 05-07-2017 K08M4_RS12740 b2ee171b20c9f3fab5b72d19ba892ea0 949 SUPERFAMILY SSF81593 292 441 1.57E-43 T 05-07-2017 K08M4_RS12740 b2ee171b20c9f3fab5b72d19ba892ea0 949 Gene3D G3DSA:3.30.460.10 116 290 5.8E-61 T 05-07-2017 K08M4_RS12740 b2ee171b20c9f3fab5b72d19ba892ea0 949 Gene3D G3DSA:3.30.460.10 643 815 7.3E-57 T 05-07-2017 K08M4_RS12740 b2ee171b20c9f3fab5b72d19ba892ea0 949 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 557 809 9.8E-95 T 05-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 K08M4_RS12740 b2ee171b20c9f3fab5b72d19ba892ea0 949 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 35 281 6.4E-92 T 05-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 K08M4_RS16165 4b45050ffb8216dd9b3329cb2d717a2d 232 SMART SM00382 34 219 8.7E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS16165 4b45050ffb8216dd9b3329cb2d717a2d 232 Pfam PF00005 ABC transporter 25 170 7.6E-32 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS16165 4b45050ffb8216dd9b3329cb2d717a2d 232 SUPERFAMILY SSF52540 6 223 3.64E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16165 4b45050ffb8216dd9b3329cb2d717a2d 232 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS16165 4b45050ffb8216dd9b3329cb2d717a2d 232 Gene3D G3DSA:3.40.50.300 3 220 4.0E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09010 ae2ff9d57385983d7c9b819039daf5a3 182 Gene3D G3DSA:3.30.1380.10 67 182 1.5E-30 T 05-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 K08M4_RS09010 ae2ff9d57385983d7c9b819039daf5a3 182 Pfam PF05951 Bacterial protein of unknown function (DUF882) 34 182 2.2E-67 T 05-07-2017 IPR010275 Protein of unknown function DUF882 K08M4_RS09010 ae2ff9d57385983d7c9b819039daf5a3 182 SUPERFAMILY SSF55166 65 182 3.14E-34 T 05-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 K08M4_RS01100 b56e68c014968bb191f2358ebb5de0bb 115 Pfam PF11333 Protein of unknown function (DUF3135) 9 89 9.0E-34 T 05-07-2017 IPR021482 Protein of unknown function DUF3135 K08M4_RS03900 c52814c6dfe65cea33d1060c67d068cc 241 Gene3D G3DSA:3.40.50.720 4 241 2.1E-74 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS03900 c52814c6dfe65cea33d1060c67d068cc 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.3E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS03900 c52814c6dfe65cea33d1060c67d068cc 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.3E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS03900 c52814c6dfe65cea33d1060c67d068cc 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.3E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS03900 c52814c6dfe65cea33d1060c67d068cc 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 240 4.9E-58 T 05-07-2017 K08M4_RS03900 c52814c6dfe65cea33d1060c67d068cc 241 SUPERFAMILY SSF51735 3 240 3.61E-73 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS03900 c52814c6dfe65cea33d1060c67d068cc 241 TIGRFAM TIGR01831 fabG_rel: putative 3-oxoacyl-(acyl-carrier-protein) reductase 5 241 5.2E-127 T 05-07-2017 IPR011285 3-oxoacyl-(acyl-carrier-protein) reductase, putative KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS03900 c52814c6dfe65cea33d1060c67d068cc 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 194 0.0022 T 05-07-2017 K08M4_RS03900 c52814c6dfe65cea33d1060c67d068cc 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.2E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS03900 c52814c6dfe65cea33d1060c67d068cc 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.2E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS03900 c52814c6dfe65cea33d1060c67d068cc 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 3.2E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS03900 c52814c6dfe65cea33d1060c67d068cc 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 3.2E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS03900 c52814c6dfe65cea33d1060c67d068cc 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 3.2E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS03900 c52814c6dfe65cea33d1060c67d068cc 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.2E-43 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05685 110faa5addd4851a1340e83dacda7a1c 489 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 23 243 1.6E-18 T 05-07-2017 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 K08M4_RS09215 2aafb37cb563f0dd3d1109963c7b89cf 342 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 106 120 - T 05-07-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 K08M4_RS09215 2aafb37cb563f0dd3d1109963c7b89cf 342 Pfam PF00849 RNA pseudouridylate synthase 68 208 5.5E-17 T 05-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS09215 2aafb37cb563f0dd3d1109963c7b89cf 342 SUPERFAMILY SSF55120 68 238 4.93E-42 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS09215 2aafb37cb563f0dd3d1109963c7b89cf 342 SUPERFAMILY SSF55174 4 96 8.92E-12 T 05-07-2017 K08M4_RS09215 2aafb37cb563f0dd3d1109963c7b89cf 342 Pfam PF01479 S4 domain 4 43 7.5E-11 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS09215 2aafb37cb563f0dd3d1109963c7b89cf 342 SMART SM00363 3 73 3.7E-9 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS09215 2aafb37cb563f0dd3d1109963c7b89cf 342 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 72 232 1.3E-55 T 05-07-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 K08M4_RS09215 2aafb37cb563f0dd3d1109963c7b89cf 342 Gene3D G3DSA:3.10.290.10 3 59 9.1E-16 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 SUPERFAMILY SSF52172 6 181 3.47E-6 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 348 357 - T 05-07-2017 IPR025944 Sigma-54 interaction domain, conserved site K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 160 173 - T 05-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 449 466 2.2E-10 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 466 486 2.2E-10 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 SUPERFAMILY SSF46689 433 485 9.41E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 SUPERFAMILY SSF46689 348 391 9.41E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 Gene3D G3DSA:3.40.50.300 133 308 6.3E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 222 237 - T 05-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 Gene3D G3DSA:1.10.10.60 423 485 4.7E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 SUPERFAMILY SSF52540 136 377 7.43E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 Pfam PF06490 Flagellar regulatory protein FleQ 6 114 4.0E-32 T 05-07-2017 IPR010518 Flagellar regulatory FleQ K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 SMART SM00382 156 300 1.3E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 Pfam PF00158 Sigma-54 interaction domain 136 303 1.9E-73 T 05-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 Gene3D G3DSA:1.10.8.60 309 380 3.4E-20 T 05-07-2017 K08M4_RS04135 257cef55e38c729d8b208b596652817b 487 Pfam PF02954 Bacterial regulatory protein, Fis family 443 483 1.1E-13 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS07435 28e7e73b2ee28828e08355a05aa2c26c 681 Gene3D G3DSA:1.10.287.950 432 647 3.4E-46 T 05-07-2017 K08M4_RS07435 28e7e73b2ee28828e08355a05aa2c26c 681 SUPERFAMILY SSF58104 371 677 6.93E-56 T 05-07-2017 K08M4_RS07435 28e7e73b2ee28828e08355a05aa2c26c 681 SMART SM00283 418 679 2.4E-40 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS07435 28e7e73b2ee28828e08355a05aa2c26c 681 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 465 676 3.5E-42 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS02860 21b5cccc71d169de90d1d27f2df08bd3 305 SUPERFAMILY SSF52540 3 227 5.22E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02860 21b5cccc71d169de90d1d27f2df08bd3 305 Pfam PF00005 ABC transporter 20 164 1.3E-33 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS02860 21b5cccc71d169de90d1d27f2df08bd3 305 SMART SM00382 29 213 7.3E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS02860 21b5cccc71d169de90d1d27f2df08bd3 305 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS02860 21b5cccc71d169de90d1d27f2df08bd3 305 Gene3D G3DSA:3.40.50.300 3 226 1.2E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16695 068acfd16afd8a32a527aa8b0c6cb1b7 450 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 213 226 - T 05-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 K08M4_RS16695 068acfd16afd8a32a527aa8b0c6cb1b7 450 Gene3D G3DSA:3.30.420.40 374 432 9.5E-17 T 05-07-2017 K08M4_RS16695 068acfd16afd8a32a527aa8b0c6cb1b7 450 Gene3D G3DSA:3.30.420.40 219 241 9.5E-17 T 05-07-2017 K08M4_RS16695 068acfd16afd8a32a527aa8b0c6cb1b7 450 Pfam PF00012 Hsp70 protein 129 258 6.5E-11 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS16695 068acfd16afd8a32a527aa8b0c6cb1b7 450 Gene3D G3DSA:3.30.420.40 85 218 1.3E-29 T 05-07-2017 K08M4_RS16695 068acfd16afd8a32a527aa8b0c6cb1b7 450 Gene3D G3DSA:3.30.420.40 2 43 1.3E-29 T 05-07-2017 K08M4_RS16695 068acfd16afd8a32a527aa8b0c6cb1b7 450 SUPERFAMILY SSF53067 85 205 1.07E-25 T 05-07-2017 K08M4_RS16695 068acfd16afd8a32a527aa8b0c6cb1b7 450 SUPERFAMILY SSF53067 1 44 1.07E-25 T 05-07-2017 K08M4_RS16695 068acfd16afd8a32a527aa8b0c6cb1b7 450 SUPERFAMILY SSF53067 207 275 2.04E-30 T 05-07-2017 K08M4_RS16695 068acfd16afd8a32a527aa8b0c6cb1b7 450 SUPERFAMILY SSF53067 328 447 2.04E-30 T 05-07-2017 K08M4_RS14550 f79102826644a2ae15f9f812076b1573 154 Gene3D G3DSA:3.30.70.920 71 145 3.0E-22 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS14550 f79102826644a2ae15f9f812076b1573 154 SMART SM00344 8 115 2.9E-40 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 K08M4_RS14550 f79102826644a2ae15f9f812076b1573 154 SUPERFAMILY SSF46785 7 68 5.88E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS14550 f79102826644a2ae15f9f812076b1573 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 3.0E-10 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS14550 f79102826644a2ae15f9f812076b1573 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 3.0E-10 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS14550 f79102826644a2ae15f9f812076b1573 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 3.0E-10 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS14550 f79102826644a2ae15f9f812076b1573 154 Pfam PF13404 AsnC-type helix-turn-helix domain 8 49 3.2E-14 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS14550 f79102826644a2ae15f9f812076b1573 154 Gene3D G3DSA:1.10.10.10 4 59 1.7E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS14550 f79102826644a2ae15f9f812076b1573 154 SUPERFAMILY SSF54909 69 154 6.3E-19 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel K08M4_RS14550 f79102826644a2ae15f9f812076b1573 154 Pfam PF01037 Lrp/AsnC ligand binding domain 75 145 1.4E-16 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS14125 fc1d8a4f822f46179bca5b67c3bac5a6 207 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 05-07-2017 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 K08M4_RS14125 fc1d8a4f822f46179bca5b67c3bac5a6 207 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 4 184 4.5E-74 T 05-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 K08M4_RS14125 fc1d8a4f822f46179bca5b67c3bac5a6 207 Pfam PF00625 Guanylate kinase 5 185 1.1E-59 T 05-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit K08M4_RS14125 fc1d8a4f822f46179bca5b67c3bac5a6 207 Hamap MF_00328 Guanylate kinase [gmk]. 2 187 37.169 T 05-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 K08M4_RS14125 fc1d8a4f822f46179bca5b67c3bac5a6 207 Gene3D G3DSA:3.40.50.300 2 26 8.6E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14125 fc1d8a4f822f46179bca5b67c3bac5a6 207 Gene3D G3DSA:3.40.50.300 88 203 8.6E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14125 fc1d8a4f822f46179bca5b67c3bac5a6 207 SMART SM00072 3 187 2.2E-72 T 05-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit K08M4_RS14125 fc1d8a4f822f46179bca5b67c3bac5a6 207 Gene3D G3DSA:3.30.63.10 35 87 4.4E-28 T 05-07-2017 K08M4_RS14125 fc1d8a4f822f46179bca5b67c3bac5a6 207 SUPERFAMILY SSF52540 3 189 2.38E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15985 ba7adcf96b3dbc274d7df958d2885a03 287 SUPERFAMILY SSF161098 22 274 2.15E-40 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS15985 ba7adcf96b3dbc274d7df958d2885a03 287 Gene3D G3DSA:1.10.3720.10 16 283 1.6E-44 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS15985 ba7adcf96b3dbc274d7df958d2885a03 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 283 8.6E-27 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS15985 ba7adcf96b3dbc274d7df958d2885a03 287 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 17 283 5.4E-97 T 05-07-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 K08M4_RS19020 a6e35a2d822a2aed776aabede3ea1466 295 Gene3D G3DSA:1.10.443.10 104 284 1.2E-46 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS19020 a6e35a2d822a2aed776aabede3ea1466 295 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 12 92 1.8E-18 T 05-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 K08M4_RS19020 a6e35a2d822a2aed776aabede3ea1466 295 Gene3D G3DSA:1.10.150.130 11 91 1.0E-5 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal K08M4_RS19020 a6e35a2d822a2aed776aabede3ea1466 295 SUPERFAMILY SSF56349 11 279 4.71E-55 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS19020 a6e35a2d822a2aed776aabede3ea1466 295 Pfam PF00589 Phage integrase family 109 270 1.9E-39 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS14030 3b5e5f46a84f4b32ccdfcfe52ef5ab09 196 SUPERFAMILY SSF48498 81 191 2.82E-11 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal K08M4_RS14030 3b5e5f46a84f4b32ccdfcfe52ef5ab09 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 58 4.8E-9 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS14030 3b5e5f46a84f4b32ccdfcfe52ef5ab09 196 SUPERFAMILY SSF46689 4 78 5.34E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS14030 3b5e5f46a84f4b32ccdfcfe52ef5ab09 196 Hamap MF_01839 Nucleoid occlusion factor SlmA [slmA]. 1 196 41.045 T 05-07-2017 IPR023769 Nucleoid occlusion factor SlmA GO:0010974 K08M4_RS14030 3b5e5f46a84f4b32ccdfcfe52ef5ab09 196 Gene3D G3DSA:1.10.357.10 5 192 2.2E-39 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS00455 38e54fb773847f50d1bd91a7ab3181ce 198 Pfam PF03942 DTW domain 5 176 7.0E-45 T 05-07-2017 IPR005636 DTW K08M4_RS00455 38e54fb773847f50d1bd91a7ab3181ce 198 SMART SM01144 3 193 2.2E-55 T 05-07-2017 IPR005636 DTW K08M4_RS01540 4a402df7b376c717245dc23f8f6af0ce 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 4.6E-33 T 05-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 K08M4_RS01540 4a402df7b376c717245dc23f8f6af0ce 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 4.6E-33 T 05-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 K08M4_RS01540 4a402df7b376c717245dc23f8f6af0ce 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 4.6E-33 T 05-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 K08M4_RS01540 4a402df7b376c717245dc23f8f6af0ce 177 SUPERFAMILY SSF56053 1 82 2.62E-24 T 05-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01540 4a402df7b376c717245dc23f8f6af0ce 177 PIRSF PIRSF002162 1 177 2.7E-44 T 05-07-2017 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01540 4a402df7b376c717245dc23f8f6af0ce 177 Pfam PF00347 Ribosomal protein L6 91 164 2.4E-18 T 05-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01540 4a402df7b376c717245dc23f8f6af0ce 177 Pfam PF00347 Ribosomal protein L6 11 82 5.1E-19 T 05-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01540 4a402df7b376c717245dc23f8f6af0ce 177 Gene3D G3DSA:3.90.930.12 2 82 8.9E-29 T 05-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01540 4a402df7b376c717245dc23f8f6af0ce 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 36.303 T 05-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 K08M4_RS01540 4a402df7b376c717245dc23f8f6af0ce 177 Gene3D G3DSA:3.90.930.12 83 177 3.0E-40 T 05-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01540 4a402df7b376c717245dc23f8f6af0ce 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 05-07-2017 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01540 4a402df7b376c717245dc23f8f6af0ce 177 SUPERFAMILY SSF56053 83 177 8.2E-36 T 05-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01540 4a402df7b376c717245dc23f8f6af0ce 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 8.0E-74 T 05-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 K08M4_RS03115 67c126ea2ce05688462db814cff5df06 151 Gene3D G3DSA:2.30.30.180 88 148 6.5E-12 T 05-07-2017 IPR028998 Ribosome maturation factor RimP, C-terminal K08M4_RS03115 67c126ea2ce05688462db814cff5df06 151 SUPERFAMILY SSF75420 2 83 4.58E-25 T 05-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal K08M4_RS03115 67c126ea2ce05688462db814cff5df06 151 SUPERFAMILY SSF74942 84 151 1.83E-16 T 05-07-2017 IPR028998 Ribosome maturation factor RimP, C-terminal K08M4_RS03115 67c126ea2ce05688462db814cff5df06 151 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 151 23.835 T 05-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 K08M4_RS03115 67c126ea2ce05688462db814cff5df06 151 Gene3D G3DSA:3.30.300.70 2 80 6.0E-32 T 05-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal K08M4_RS03115 67c126ea2ce05688462db814cff5df06 151 Pfam PF02576 Putative ribosome maturation factor RimP 13 147 1.1E-47 T 05-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 K08M4_RS05235 4a6661c84dbdcc99aae08b14f1563b6d 423 Pfam PF04285 Protein of unknown function (DUF444) 3 421 3.8E-188 T 05-07-2017 IPR006698 Uncharacterised protein family UPF0229 K08M4_RS05235 4a6661c84dbdcc99aae08b14f1563b6d 423 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 423 40.335 T 05-07-2017 IPR006698 Uncharacterised protein family UPF0229 K08M4_RS21445 61f81ed6326ffd28ae4566d7ec14b9a3 128 Gene3D G3DSA:1.20.120.550 2 122 4.2E-19 T 05-07-2017 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain K08M4_RS21445 61f81ed6326ffd28ae4566d7ec14b9a3 128 Pfam PF01124 MAPEG family 3 119 7.9E-25 T 05-07-2017 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein K08M4_RS21445 61f81ed6326ffd28ae4566d7ec14b9a3 128 SUPERFAMILY SSF161084 2 124 1.7E-27 T 05-07-2017 K08M4_RS16650 f5f193771fe515593581d75faebcb11f 104 Hamap MF_00683 UPF0265 protein YeeX [yeeX]. 1 95 24.126 T 05-07-2017 IPR007458 Protein of unknown function DUF496 K08M4_RS16650 f5f193771fe515593581d75faebcb11f 104 PIRSF PIRSF028773 1 104 5.6E-46 T 05-07-2017 IPR007458 Protein of unknown function DUF496 K08M4_RS16650 f5f193771fe515593581d75faebcb11f 104 Pfam PF04363 Protein of unknown function (DUF496) 1 92 8.6E-42 T 05-07-2017 IPR007458 Protein of unknown function DUF496 K08M4_RS16650 f5f193771fe515593581d75faebcb11f 104 ProDom PD030876 UPF0265 YEEX HELIX ALPHA BFL460 UNCHARACTERIZED FN0411 HI1168 VPA1226 BCR 1 92 1.0E-43 T 05-07-2017 IPR007458 Protein of unknown function DUF496 K08M4_RS16240 dd46d029094a9d23231862257c71b3af 475 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 05-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 K08M4_RS16240 dd46d029094a9d23231862257c71b3af 475 Gene3D G3DSA:3.40.309.10 263 445 8.4E-71 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 K08M4_RS16240 dd46d029094a9d23231862257c71b3af 475 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 23 468 4.0E-200 T 05-07-2017 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 K08M4_RS16240 dd46d029094a9d23231862257c71b3af 475 Pfam PF00171 Aldehyde dehydrogenase family 16 469 2.2E-168 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS16240 dd46d029094a9d23231862257c71b3af 475 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 05-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 K08M4_RS16240 dd46d029094a9d23231862257c71b3af 475 SUPERFAMILY SSF53720 17 473 1.7E-164 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 K08M4_RS16240 dd46d029094a9d23231862257c71b3af 475 Gene3D G3DSA:3.40.605.10 17 262 1.3E-96 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 97 106 - T 05-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 Gene3D G3DSA:3.40.120.10 5 153 1.8E-47 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 8 443 1.8E-201 T 05-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 Gene3D G3DSA:3.30.310.50 370 443 6.4E-16 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 442 5.9E-13 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 SUPERFAMILY SSF53738 4 182 5.1E-48 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 5 136 6.5E-45 T 05-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 4 445 46.745 T 05-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 368 9.2E-31 T 05-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 Gene3D G3DSA:3.40.120.10 177 251 1.1E-26 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 SUPERFAMILY SSF55957 358 444 3.79E-22 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 SUPERFAMILY SSF53738 157 257 6.67E-29 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 SUPERFAMILY SSF53738 259 366 1.49E-28 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 255 4.5E-19 T 05-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 4.6E-12 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 4.6E-12 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 96 110 4.6E-12 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS03090 f9ce6c18275814ebc5cc26192f80c971 446 Gene3D G3DSA:3.40.120.10 252 368 2.0E-30 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS19180 bca1a4da8deaafd1d2a121ec0083297c 712 SUPERFAMILY SSF90123 160 465 1.7E-34 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS19180 bca1a4da8deaafd1d2a121ec0083297c 712 Gene3D G3DSA:1.20.1560.10 166 464 2.2E-29 T 05-07-2017 K08M4_RS19180 bca1a4da8deaafd1d2a121ec0083297c 712 Pfam PF00005 ABC transporter 502 650 9.6E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS19180 bca1a4da8deaafd1d2a121ec0083297c 712 Pfam PF00664 ABC transporter transmembrane region 174 418 2.0E-9 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS19180 bca1a4da8deaafd1d2a121ec0083297c 712 SUPERFAMILY SSF52540 463 709 3.93E-30 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19180 bca1a4da8deaafd1d2a121ec0083297c 712 Gene3D G3DSA:3.40.50.300 490 709 2.8E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19180 bca1a4da8deaafd1d2a121ec0083297c 712 SMART SM00382 511 696 2.2E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS00565 ad8db7a88908eadf3e87dfe5fb2f9b5f 322 PIRSF PIRSF003097 26 318 2.6E-59 T 05-07-2017 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 K08M4_RS00565 ad8db7a88908eadf3e87dfe5fb2f9b5f 322 Pfam PF02687 FtsX-like permease family 197 317 4.8E-11 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 K08M4_RS00150 38a36f91cf443c8c311b85afd26a6380 460 Gene3D G3DSA:2.60.40.420 29 154 2.6E-35 T 05-07-2017 IPR008972 Cupredoxin K08M4_RS00150 38a36f91cf443c8c311b85afd26a6380 460 SUPERFAMILY SSF49503 309 459 1.56E-33 T 05-07-2017 IPR008972 Cupredoxin K08M4_RS00150 38a36f91cf443c8c311b85afd26a6380 460 SUPERFAMILY SSF49503 158 275 3.66E-16 T 05-07-2017 IPR008972 Cupredoxin K08M4_RS00150 38a36f91cf443c8c311b85afd26a6380 460 Pfam PF07732 Multicopper oxidase 44 155 5.8E-38 T 05-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 K08M4_RS00150 38a36f91cf443c8c311b85afd26a6380 460 SUPERFAMILY SSF49503 33 154 1.51E-38 T 05-07-2017 IPR008972 Cupredoxin K08M4_RS00150 38a36f91cf443c8c311b85afd26a6380 460 Pfam PF07731 Multicopper oxidase 358 459 1.0E-25 T 05-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 K08M4_RS00150 38a36f91cf443c8c311b85afd26a6380 460 ProSitePatterns PS00080 Multicopper oxidases signature 2. 442 453 - T 05-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 K08M4_RS00150 38a36f91cf443c8c311b85afd26a6380 460 Pfam PF00394 Multicopper oxidase 174 270 8.9E-7 T 05-07-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 K08M4_RS00150 38a36f91cf443c8c311b85afd26a6380 460 Gene3D G3DSA:2.60.40.420 345 459 7.5E-35 T 05-07-2017 IPR008972 Cupredoxin K08M4_RS00150 38a36f91cf443c8c311b85afd26a6380 460 Gene3D G3DSA:2.60.40.420 161 272 1.8E-18 T 05-07-2017 IPR008972 Cupredoxin K08M4_RS12915 c3697f984045b66e897f6943101b3102 219 SUPERFAMILY SSF48498 89 206 3.56E-5 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal K08M4_RS12915 c3697f984045b66e897f6943101b3102 219 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 61 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site K08M4_RS12915 c3697f984045b66e897f6943101b3102 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 2.0E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS12915 c3697f984045b66e897f6943101b3102 219 Gene3D G3DSA:1.10.357.10 2 205 1.5E-38 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS12915 c3697f984045b66e897f6943101b3102 219 SUPERFAMILY SSF46689 7 83 9.75E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS13870 f523c08c623b3d460336dc4c397fa1bb 377 SUPERFAMILY SSF53756 21 375 3.14E-58 T 05-07-2017 K08M4_RS13870 f523c08c623b3d460336dc4c397fa1bb 377 Gene3D G3DSA:3.40.50.2000 198 352 9.3E-15 T 05-07-2017 K08M4_RS13870 f523c08c623b3d460336dc4c397fa1bb 377 Pfam PF13477 Glycosyl transferase 4-like 5 155 2.3E-23 T 05-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 K08M4_RS13870 f523c08c623b3d460336dc4c397fa1bb 377 Pfam PF00534 Glycosyl transferases group 1 198 352 1.7E-26 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 PIRSF PIRSF000171 1 537 2.8E-40 T 05-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 7 520 4.3E-212 T 05-07-2017 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 Gene3D G3DSA:1.20.58.100 417 521 1.0E-34 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 Gene3D G3DSA:3.50.50.60 349 413 4.8E-105 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 Gene3D G3DSA:3.50.50.60 3 243 4.8E-105 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 Gene3D G3DSA:3.90.700.10 244 348 6.2E-37 T 05-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 SUPERFAMILY SSF56425 238 353 9.87E-41 T 05-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 SUPERFAMILY SSF51905 5 255 2.45E-76 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 SUPERFAMILY SSF51905 356 447 2.45E-76 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 3.6E-9 T 05-07-2017 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.6E-9 T 05-07-2017 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 Pfam PF00890 FAD binding domain 10 392 1.5E-101 T 05-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 SUPERFAMILY SSF46977 425 525 2.88E-32 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 370 377 9.6E-6 T 05-07-2017 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 9.6E-6 T 05-07-2017 K08M4_RS02420 79d1ef9912e5ad8dfd23029a3deb4398 538 Pfam PF02910 Fumarate reductase flavoprotein C-term 441 521 1.1E-14 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS00180 aeb79dc5f18fd81036fc87f388b1d792 254 Hamap MF_00443 Thiazole synthase [thiG]. 1 253 43.187 T 05-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 K08M4_RS00180 aeb79dc5f18fd81036fc87f388b1d792 254 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 247 6.6E-110 T 05-07-2017 K08M4_RS00180 aeb79dc5f18fd81036fc87f388b1d792 254 SUPERFAMILY SSF110399 1 236 1.31E-85 T 05-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 K08M4_RS00180 aeb79dc5f18fd81036fc87f388b1d792 254 Gene3D G3DSA:3.20.20.70 1 252 2.9E-62 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS06515 5f250874254f2c383523cebc945d7caa 337 Pfam PF10974 Protein of unknown function (DUF2804) 15 336 3.7E-93 T 05-07-2017 IPR021243 Protein of unknown function DUF2804 K08M4_RS06515 5f250874254f2c383523cebc945d7caa 337 SUPERFAMILY SSF159245 62 288 6.54E-7 T 05-07-2017 K08M4_RS02750 1d58946d1cff25591a953e27d522a71f 82 ProSitePatterns PS00732 Ribosomal protein S16 signature. 2 11 - T 05-07-2017 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS02750 1d58946d1cff25591a953e27d522a71f 82 Pfam PF00886 Ribosomal protein S16 8 68 1.9E-23 T 05-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS02750 1d58946d1cff25591a953e27d522a71f 82 Gene3D G3DSA:3.30.1320.10 1 79 3.4E-32 T 05-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS02750 1d58946d1cff25591a953e27d522a71f 82 SUPERFAMILY SSF54565 1 76 6.28E-28 T 05-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS02750 1d58946d1cff25591a953e27d522a71f 82 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 79 7.7E-27 T 05-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS02750 1d58946d1cff25591a953e27d522a71f 82 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 23.02 T 05-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 277 4.3E-25 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 4.3E-25 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 4.3E-25 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 297 320 4.3E-25 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 Gene3D G3DSA:3.40.50.1370 5 143 1.5E-54 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 SUPERFAMILY SSF53671 4 333 2.36E-97 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 333 81.766 T 05-07-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 Gene3D G3DSA:3.40.50.1370 144 319 1.5E-72 T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 1.5E-44 T 05-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 311 322 5.7E-32 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 5.7E-32 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 5.7E-32 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 5.7E-32 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 230 240 5.7E-32 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 05-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 330 7.2E-56 T 05-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 K08M4_RS01900 74f7242479d86e603b18f561c78cce50 334 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 332 7.9E-132 T 05-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 Gene3D G3DSA:3.40.50.1440 14 214 1.7E-93 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 05-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 6.6E-40 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 SUPERFAMILY SSF52490 13 208 5.23E-69 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 396 38.326 T 05-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 SMART SM00865 207 325 7.4E-56 T 05-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 PRINTS PR00423 Cell division protein FtsZ signature 126 147 6.4E-52 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 PRINTS PR00423 Cell division protein FtsZ signature 189 211 6.4E-52 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 PRINTS PR00423 Cell division protein FtsZ signature 98 118 6.4E-52 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 PRINTS PR00423 Cell division protein FtsZ signature 212 233 6.4E-52 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 05-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 Gene3D G3DSA:3.30.1330.20 215 322 3.2E-47 T 05-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 SUPERFAMILY SSF55307 204 320 9.39E-43 T 05-07-2017 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 SMART SM00864 13 205 2.4E-113 T 05-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 328 2.3E-136 T 05-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 K08M4_RS12545 6622f1aea1190068056c00822ab94ea6 409 Pfam PF12327 FtsZ family, C-terminal domain 222 316 2.1E-36 T 05-07-2017 IPR024757 Cell division protein FtsZ, C-terminal K08M4_RS18050 881a724fd1b35952df313ab13e90b03c 157 Pfam PF01936 NYN domain 4 151 7.0E-40 T 05-07-2017 IPR021139 NYN domain, limkain-b1-type K08M4_RS18050 881a724fd1b35952df313ab13e90b03c 157 Gene3D G3DSA:3.40.50.1010 1 153 4.4E-50 T 05-07-2017 IPR029060 PIN domain-like K08M4_RS07320 5b8daf3f69cfc22e4ac066dd587c3ebc 395 Gene3D G3DSA:3.90.550.10 57 247 4.8E-15 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS07320 5b8daf3f69cfc22e4ac066dd587c3ebc 395 Pfam PF13641 Glycosyltransferase like family 2 57 277 2.3E-18 T 05-07-2017 K08M4_RS07320 5b8daf3f69cfc22e4ac066dd587c3ebc 395 SUPERFAMILY SSF53448 52 325 4.69E-31 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS20450 6f0ef5c77035028ba5b10ae75ee607b7 150 Gene3D G3DSA:3.90.79.10 9 134 1.4E-22 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS20450 6f0ef5c77035028ba5b10ae75ee607b7 150 Pfam PF00293 NUDIX domain 16 122 4.3E-18 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 K08M4_RS20450 6f0ef5c77035028ba5b10ae75ee607b7 150 SUPERFAMILY SSF55811 10 136 2.3E-25 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS13005 81e9458cc87795659ae75cc15b686980 85 Gene3D G3DSA:2.40.50.100 20 82 5.8E-32 T 05-07-2017 K08M4_RS13005 81e9458cc87795659ae75cc15b686980 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 82 2.5E-42 T 05-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13005 81e9458cc87795659ae75cc15b686980 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 28.801 T 05-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13005 81e9458cc87795659ae75cc15b686980 85 Pfam PF01016 Ribosomal L27 protein 2 82 4.4E-39 T 05-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13005 81e9458cc87795659ae75cc15b686980 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 2.2E-38 T 05-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13005 81e9458cc87795659ae75cc15b686980 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 2.2E-38 T 05-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13005 81e9458cc87795659ae75cc15b686980 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 2.2E-38 T 05-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13005 81e9458cc87795659ae75cc15b686980 85 SUPERFAMILY SSF110324 2 80 3.84E-34 T 05-07-2017 K08M4_RS13005 81e9458cc87795659ae75cc15b686980 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 3.0E-17 T 05-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13005 81e9458cc87795659ae75cc15b686980 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 05-07-2017 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS16975 2ddfcee83090c514fcac97877ae3422b 292 Gene3D G3DSA:3.40.50.620 7 132 5.6E-12 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS16975 2ddfcee83090c514fcac97877ae3422b 292 Pfam PF02698 DUF218 domain 7 134 1.6E-13 T 05-07-2017 IPR003848 Domain of unknown function DUF218 K08M4_RS02270 64565e9aea0321d8b6583db5011cc953 352 Pfam PF01032 FecCD transport family 33 346 2.2E-89 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 K08M4_RS02270 64565e9aea0321d8b6583db5011cc953 352 Gene3D G3DSA:1.10.3470.10 21 350 1.6E-97 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS02270 64565e9aea0321d8b6583db5011cc953 352 SUPERFAMILY SSF81345 21 345 1.18E-75 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS06505 ece727bf6a2a8334a5405a8b19b846c8 474 Gene3D G3DSA:3.30.420.10 3 197 2.0E-82 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS06505 ece727bf6a2a8334a5405a8b19b846c8 474 Pfam PF00929 Exonuclease 11 191 1.2E-22 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS06505 ece727bf6a2a8334a5405a8b19b846c8 474 SUPERFAMILY SSF53098 7 472 8.28E-139 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS06505 ece727bf6a2a8334a5405a8b19b846c8 474 SMART SM00479 8 201 0.0062 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS06505 ece727bf6a2a8334a5405a8b19b846c8 474 Pfam PF08411 Exonuclease C-terminal 210 470 1.5E-105 T 05-07-2017 IPR013620 Exonuclease C-terminal GO:0006281|GO:0008852 K08M4_RS06505 ece727bf6a2a8334a5405a8b19b846c8 474 PIRSF PIRSF000977 1 474 2.7E-197 T 05-07-2017 IPR023607 Exodeoxyribonuclease I GO:0004529 K08M4_RS09115 7f234a2e458d633ad7e9fae6c26a88b0 411 SUPERFAMILY SSF142433 253 386 3.27E-5 T 05-07-2017 IPR008136 CinA, C-terminal K08M4_RS09115 7f234a2e458d633ad7e9fae6c26a88b0 411 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 354 5.5E-77 T 05-07-2017 IPR008135 Competence-induced protein CinA K08M4_RS09115 7f234a2e458d633ad7e9fae6c26a88b0 411 Pfam PF00994 Probable molybdopterin binding domain 5 170 9.1E-30 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS09115 7f234a2e458d633ad7e9fae6c26a88b0 411 PIRSF PIRSF006728 1 392 1.3E-105 T 05-07-2017 IPR008135 Competence-induced protein CinA K08M4_RS09115 7f234a2e458d633ad7e9fae6c26a88b0 411 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 166 3.5E-25 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS09115 7f234a2e458d633ad7e9fae6c26a88b0 411 Gene3D G3DSA:3.40.980.10 2 199 6.9E-24 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS09115 7f234a2e458d633ad7e9fae6c26a88b0 411 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 411 103.009 T 05-07-2017 IPR008135 Competence-induced protein CinA K08M4_RS09115 7f234a2e458d633ad7e9fae6c26a88b0 411 SUPERFAMILY SSF53218 2 204 6.02E-32 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS09115 7f234a2e458d633ad7e9fae6c26a88b0 411 SMART SM00852 5 172 1.4E-28 T 05-07-2017 IPR001453 MoaB/Mog domain K08M4_RS09725 682286449680381e38650afd0d70c545 1039 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 28 199 1.1E-41 T 05-07-2017 IPR025199 DNA translocase FtsK, 4TM region K08M4_RS09725 682286449680381e38650afd0d70c545 1039 Gene3D G3DSA:3.40.50.300 628 934 1.8E-90 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09725 682286449680381e38650afd0d70c545 1039 SUPERFAMILY SSF46785 971 1036 7.48E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS09725 682286449680381e38650afd0d70c545 1039 Pfam PF09397 Ftsk gamma domain 973 1033 1.6E-25 T 05-07-2017 IPR018541 FtsK gamma domain K08M4_RS09725 682286449680381e38650afd0d70c545 1039 Pfam PF01580 FtsK/SpoIIIE family 656 867 9.6E-69 T 05-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 K08M4_RS09725 682286449680381e38650afd0d70c545 1039 SUPERFAMILY SSF52540 628 940 4.12E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09725 682286449680381e38650afd0d70c545 1039 SMART SM00843 971 1036 1.4E-37 T 05-07-2017 IPR018541 FtsK gamma domain K08M4_RS04710 4efe9b3291d4c81d1bf0f1477f3ef9d5 182 Pfam PF00881 Nitroreductase family 8 161 3.5E-23 T 05-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 K08M4_RS04710 4efe9b3291d4c81d1bf0f1477f3ef9d5 182 PIRSF PIRSF000232 1 182 3.2E-62 T 05-07-2017 IPR026021 Putative NAD(P)H nitroreductase YdjA-like K08M4_RS04710 4efe9b3291d4c81d1bf0f1477f3ef9d5 182 SUPERFAMILY SSF55469 1 181 8.51E-42 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 K08M4_RS04710 4efe9b3291d4c81d1bf0f1477f3ef9d5 182 Gene3D G3DSA:3.40.109.10 1 181 2.8E-42 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 K08M4_RS03075 6c8db16dccc029ac488aa25b38d2d879 209 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 11 207 29.885 T 05-07-2017 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 K08M4_RS03075 6c8db16dccc029ac488aa25b38d2d879 209 SUPERFAMILY SSF53335 30 209 3.03E-43 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS03075 6c8db16dccc029ac488aa25b38d2d879 209 PIRSF PIRSF005461 1 209 4.2E-80 T 05-07-2017 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 K08M4_RS03075 6c8db16dccc029ac488aa25b38d2d879 209 Gene3D G3DSA:3.40.50.150 1 208 7.2E-73 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS03075 6c8db16dccc029ac488aa25b38d2d879 209 Pfam PF01728 FtsJ-like methyltransferase 31 207 1.6E-57 T 05-07-2017 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 K08M4_RS02925 7b92b8bb8dec0521fe73fead8778e1a8 122 ProDom PD020773 UPF0231 YACL UNCHARACTERISED UCP006287 VC0605 UNCHARACTERIZED 3'REGION VV2750 BCR OXIDASE 1 120 4.0E-39 T 05-07-2017 IPR008249 Uncharacterised protein family UPF0231 K08M4_RS02925 7b92b8bb8dec0521fe73fead8778e1a8 122 Pfam PF06062 Uncharacterised protein family (UPF0231) 1 120 3.0E-40 T 05-07-2017 IPR008249 Uncharacterised protein family UPF0231 K08M4_RS02925 7b92b8bb8dec0521fe73fead8778e1a8 122 PIRSF PIRSF006287 1 122 3.4E-43 T 05-07-2017 IPR008249 Uncharacterised protein family UPF0231 K08M4_RS02925 7b92b8bb8dec0521fe73fead8778e1a8 122 Hamap MF_01053 UPF0231 protein YacL [yacL]. 1 122 27.698 T 05-07-2017 IPR008249 Uncharacterised protein family UPF0231 K08M4_RS10535 1badcec511e75d0520eb02da9621300b 1127 Gene3D G3DSA:1.10.10.60 1022 1076 1.3E-5 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS10535 1badcec511e75d0520eb02da9621300b 1127 SUPERFAMILY SSF46689 1076 1124 8.51E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS10535 1badcec511e75d0520eb02da9621300b 1127 Pfam PF07494 Two component regulator propeller 284 307 0.0058 T 05-07-2017 IPR011110 Two component regulator propeller K08M4_RS10535 1badcec511e75d0520eb02da9621300b 1127 SMART SM00342 1040 1122 9.2E-27 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS10535 1badcec511e75d0520eb02da9621300b 1127 Pfam PF12833 Helix-turn-helix domain 1047 1123 2.5E-23 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS10535 1badcec511e75d0520eb02da9621300b 1127 SUPERFAMILY SSF63829 253 372 5.75E-9 T 05-07-2017 K08M4_RS10535 1badcec511e75d0520eb02da9621300b 1127 SUPERFAMILY SSF63829 519 557 5.75E-9 T 05-07-2017 K08M4_RS10535 1badcec511e75d0520eb02da9621300b 1127 SUPERFAMILY SSF63829 413 480 5.75E-9 T 05-07-2017 K08M4_RS10535 1badcec511e75d0520eb02da9621300b 1127 Gene3D G3DSA:1.10.10.60 1077 1124 4.5E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS10535 1badcec511e75d0520eb02da9621300b 1127 Gene3D G3DSA:2.120.10.30 205 409 7.0E-4 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like K08M4_RS10535 1badcec511e75d0520eb02da9621300b 1127 SUPERFAMILY SSF63829 260 327 1.31E-5 T 05-07-2017 K08M4_RS10535 1badcec511e75d0520eb02da9621300b 1127 SUPERFAMILY SSF63829 92 223 1.31E-5 T 05-07-2017 K08M4_RS10535 1badcec511e75d0520eb02da9621300b 1127 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 1077 1118 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 K08M4_RS10535 1badcec511e75d0520eb02da9621300b 1127 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 1091 1106 9.0E-6 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS10535 1badcec511e75d0520eb02da9621300b 1127 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 1106 1122 9.0E-6 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS17735 0f42b9e8b7ba208005b00289098e1146 468 Pfam PF00654 Voltage gated chloride channel 87 435 2.4E-95 T 05-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 K08M4_RS17735 0f42b9e8b7ba208005b00289098e1146 468 Hamap MF_01128 H(+)/Cl(-) exchange transporter ClcA [clcA]. 1 467 50.478 T 05-07-2017 IPR023861 Chloride channel, ClcA GO:0005887|GO:0006821|GO:0015108 K08M4_RS17735 0f42b9e8b7ba208005b00289098e1146 468 PRINTS PR00762 Chloride channel signature 403 422 3.6E-29 T 05-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 K08M4_RS17735 0f42b9e8b7ba208005b00289098e1146 468 PRINTS PR00762 Chloride channel signature 181 200 3.6E-29 T 05-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 K08M4_RS17735 0f42b9e8b7ba208005b00289098e1146 468 PRINTS PR00762 Chloride channel signature 350 370 3.6E-29 T 05-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 K08M4_RS17735 0f42b9e8b7ba208005b00289098e1146 468 PRINTS PR00762 Chloride channel signature 100 117 3.6E-29 T 05-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 K08M4_RS17735 0f42b9e8b7ba208005b00289098e1146 468 PRINTS PR00762 Chloride channel signature 385 401 3.6E-29 T 05-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 K08M4_RS17735 0f42b9e8b7ba208005b00289098e1146 468 SUPERFAMILY SSF81340 21 450 8.24E-116 T 05-07-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 K08M4_RS17735 0f42b9e8b7ba208005b00289098e1146 468 Gene3D G3DSA:1.10.3080.10 25 450 7.1E-110 T 05-07-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 K08M4_RS01135 f9c047491cafa40f94def7edaab8055d 182 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 2 172 3.1E-87 T 05-07-2017 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 K08M4_RS01135 f9c047491cafa40f94def7edaab8055d 182 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 1 172 42.067 T 05-07-2017 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 K08M4_RS01135 f9c047491cafa40f94def7edaab8055d 182 SUPERFAMILY SSF56235 2 172 1.91E-57 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS01135 f9c047491cafa40f94def7edaab8055d 182 PIRSF PIRSF039093 1 175 7.0E-88 T 05-07-2017 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 K08M4_RS01135 f9c047491cafa40f94def7edaab8055d 182 Pfam PF00227 Proteasome subunit 2 169 3.1E-23 T 05-07-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 K08M4_RS01135 f9c047491cafa40f94def7edaab8055d 182 Gene3D G3DSA:3.60.20.10 2 173 6.8E-86 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS17475 649fc73899e4e2d51bcd6934e02430a8 227 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 27 125 3.4E-27 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS12630 dde843ad64d66b3f17ae2a87dc2b21e1 132 SUPERFAMILY SSF52980 17 121 1.61E-18 T 05-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 K08M4_RS12630 dde843ad64d66b3f17ae2a87dc2b21e1 132 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 14 130 3.1E-34 T 05-07-2017 IPR003509 Uncharacterised protein family UPF0102 K08M4_RS12630 dde843ad64d66b3f17ae2a87dc2b21e1 132 Hamap MF_00048 UPF0102 protein YraN [yraN]. 16 128 21.632 T 05-07-2017 IPR003509 Uncharacterised protein family UPF0102 K08M4_RS12630 dde843ad64d66b3f17ae2a87dc2b21e1 132 Pfam PF02021 Uncharacterised protein family UPF0102 23 115 4.2E-25 T 05-07-2017 IPR003509 Uncharacterised protein family UPF0102 K08M4_RS12630 dde843ad64d66b3f17ae2a87dc2b21e1 132 Gene3D G3DSA:3.40.1350.10 23 130 5.8E-32 T 05-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 K08M4_RS12170 e5e23982773ca1d49379d10aaf608804 122 SUPERFAMILY SSF141371 1 120 2.75E-33 T 05-07-2017 K08M4_RS12170 e5e23982773ca1d49379d10aaf608804 122 Pfam PF07238 PilZ domain 3 100 8.0E-14 T 05-07-2017 IPR009875 PilZ domain GO:0035438 K08M4_RS12170 e5e23982773ca1d49379d10aaf608804 122 Gene3D G3DSA:2.40.10.220 1 120 1.5E-41 T 05-07-2017 K08M4_RS12170 e5e23982773ca1d49379d10aaf608804 122 PIRSF PIRSF028141 1 120 3.8E-40 T 05-07-2017 IPR027021 Cyclic di-GMP binding protein, PA4608 type K08M4_RS05880 299d4fbce37ae9c0fa15e39aa985c3dc 364 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 160 321 7.1E-25 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS05880 299d4fbce37ae9c0fa15e39aa985c3dc 364 SUPERFAMILY SSF161098 139 321 4.84E-41 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS05880 299d4fbce37ae9c0fa15e39aa985c3dc 364 Gene3D G3DSA:1.10.3720.10 137 321 2.1E-42 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 Gene3D G3DSA:3.50.50.60 234 315 2.3E-9 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 SUPERFAMILY SSF51905 2 313 2.41E-52 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 4.2E-77 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 4.2E-77 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 4.2E-77 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 4.2E-77 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 4.2E-77 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 4.2E-77 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 4.2E-77 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 4.2E-77 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 4.2E-77 T 05-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 Gene3D G3DSA:3.50.50.60 120 233 1.7E-33 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 313 5.6E-124 T 05-07-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.6E-39 T 05-07-2017 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 1.6E-39 T 05-07-2017 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 1.6E-39 T 05-07-2017 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 1.6E-39 T 05-07-2017 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 1.6E-39 T 05-07-2017 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 05-07-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 Gene3D G3DSA:3.50.50.60 5 119 2.5E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS05915 678bf69220990984c967d47004174ac0 319 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 300 1.2E-46 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS20235 1f1ca130934a24e7546547dd4c37a56e 120 Pfam PF11225 Protein of unknown function (DUF3024) 58 119 9.3E-20 T 05-07-2017 IPR021388 Bacteriophage 933W, L0084 K08M4_RS14810 4ecd6e44cc0f85013e5922e25d704ec2 481 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 85 464 5.5E-112 T 05-07-2017 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 K08M4_RS14810 4ecd6e44cc0f85013e5922e25d704ec2 481 Pfam PF02386 Cation transport protein 51 475 7.2E-49 T 05-07-2017 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 K08M4_RS14810 4ecd6e44cc0f85013e5922e25d704ec2 481 PIRSF PIRSF006247 1 481 1.3E-163 T 05-07-2017 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 K08M4_RS21885 71f02d907fc8620b48bd96e5daa91287 518 Gene3D G3DSA:3.40.50.1820 70 313 2.1E-24 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS21885 71f02d907fc8620b48bd96e5daa91287 518 Gene3D G3DSA:3.40.50.1820 364 477 2.1E-24 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS21885 71f02d907fc8620b48bd96e5daa91287 518 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 135 146 2.8E-5 T 05-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 K08M4_RS21885 71f02d907fc8620b48bd96e5daa91287 518 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 208 222 2.8E-5 T 05-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 K08M4_RS21885 71f02d907fc8620b48bd96e5daa91287 518 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 104 112 2.8E-5 T 05-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 K08M4_RS21885 71f02d907fc8620b48bd96e5daa91287 518 SUPERFAMILY SSF53474 343 460 1.21E-22 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS21885 71f02d907fc8620b48bd96e5daa91287 518 SUPERFAMILY SSF53474 70 308 1.21E-22 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS21885 71f02d907fc8620b48bd96e5daa91287 518 Pfam PF00561 alpha/beta hydrolase fold 103 472 5.8E-12 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS19110 d4af64c237c76557cb429335387ef096 300 Gene3D G3DSA:3.40.190.10 92 173 1.3E-17 T 05-07-2017 K08M4_RS19110 d4af64c237c76557cb429335387ef096 300 SUPERFAMILY SSF46785 1 84 5.07E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19110 d4af64c237c76557cb429335387ef096 300 Gene3D G3DSA:3.40.190.10 174 262 3.7E-17 T 05-07-2017 K08M4_RS19110 d4af64c237c76557cb429335387ef096 300 Pfam PF03466 LysR substrate binding domain 88 294 3.4E-32 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS19110 d4af64c237c76557cb429335387ef096 300 SUPERFAMILY SSF53850 89 296 1.59E-35 T 05-07-2017 K08M4_RS19110 d4af64c237c76557cb429335387ef096 300 Gene3D G3DSA:1.10.10.10 1 85 5.0E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19110 d4af64c237c76557cb429335387ef096 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19110 d4af64c237c76557cb429335387ef096 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19110 d4af64c237c76557cb429335387ef096 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19110 d4af64c237c76557cb429335387ef096 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.3E-21 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS12880 81d882e5db8ce68e6c0b4b17f4e438bd 585 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 17 184 9.5E-58 T 05-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 K08M4_RS12880 81d882e5db8ce68e6c0b4b17f4e438bd 585 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 407 556 3.1E-50 T 05-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 K08M4_RS12880 81d882e5db8ce68e6c0b4b17f4e438bd 585 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 444 463 - T 05-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 K08M4_RS12880 81d882e5db8ce68e6c0b4b17f4e438bd 585 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 16 580 1.3E-270 T 05-07-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 K08M4_RS12880 81d882e5db8ce68e6c0b4b17f4e438bd 585 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 209 343 1.4E-46 T 05-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 K08M4_RS12880 81d882e5db8ce68e6c0b4b17f4e438bd 585 Gene3D G3DSA:3.40.50.970 371 569 6.0E-76 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS12880 81d882e5db8ce68e6c0b4b17f4e438bd 585 SUPERFAMILY SSF52518 384 578 1.5E-68 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS12880 81d882e5db8ce68e6c0b4b17f4e438bd 585 Gene3D G3DSA:3.40.50.1220 203 370 9.9E-66 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain K08M4_RS12880 81d882e5db8ce68e6c0b4b17f4e438bd 585 SUPERFAMILY SSF52518 15 195 5.05E-63 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS12880 81d882e5db8ce68e6c0b4b17f4e438bd 585 SUPERFAMILY SSF52467 202 375 1.29E-63 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain K08M4_RS12880 81d882e5db8ce68e6c0b4b17f4e438bd 585 Gene3D G3DSA:3.40.50.970 14 191 1.9E-74 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS21350 2bb9e801726eb9d28ce7b75f42d3a6d7 498 SUPERFAMILY SSF55874 391 496 8.38E-16 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21350 2bb9e801726eb9d28ce7b75f42d3a6d7 498 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 411 496 8.3E-7 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21350 2bb9e801726eb9d28ce7b75f42d3a6d7 498 SMART SM00387 407 498 9.3E-8 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21350 2bb9e801726eb9d28ce7b75f42d3a6d7 498 Pfam PF07730 Histidine kinase 304 367 1.3E-11 T 05-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 K08M4_RS21350 2bb9e801726eb9d28ce7b75f42d3a6d7 498 Gene3D G3DSA:3.30.565.10 370 497 2.4E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21350 2bb9e801726eb9d28ce7b75f42d3a6d7 498 Pfam PF05231 MASE1 13 276 1.2E-15 T 05-07-2017 IPR007895 MASE1 K08M4_RS19340 7060892be1335dce25088aa8e024e167 474 Gene3D G3DSA:1.20.210.10 7 461 2.8E-62 T 05-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS19340 7060892be1335dce25088aa8e024e167 474 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 11 441 8.5E-97 T 05-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS19340 7060892be1335dce25088aa8e024e167 474 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 7 460 4.0E-179 T 05-07-2017 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 K08M4_RS19340 7060892be1335dce25088aa8e024e167 474 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 202 257 - T 05-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS19340 7060892be1335dce25088aa8e024e167 474 SUPERFAMILY SSF81442 8 462 4.06E-106 T 05-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS09140 d3c9fda3506d24394871971c4c8303c7 377 SUPERFAMILY SSF50621 212 358 4.19E-22 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 K08M4_RS09140 d3c9fda3506d24394871971c4c8303c7 377 Gene3D G3DSA:2.40.37.10 237 348 3.2E-13 T 05-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 K08M4_RS09140 d3c9fda3506d24394871971c4c8303c7 377 TIGRFAM TIGR01047 nspC: carboxynorspermidine decarboxylase 6 370 4.4E-164 T 05-07-2017 IPR005730 Carboxynorspermidine decarboxylase KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 K08M4_RS09140 d3c9fda3506d24394871971c4c8303c7 377 Gene3D G3DSA:3.20.20.10 27 236 4.6E-17 T 05-07-2017 IPR029066 PLP-binding barrel K08M4_RS09140 d3c9fda3506d24394871971c4c8303c7 377 PIRSF PIRSF038941 1 372 1.4E-128 T 05-07-2017 IPR005730 Carboxynorspermidine decarboxylase KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 K08M4_RS09140 d3c9fda3506d24394871971c4c8303c7 377 SUPERFAMILY SSF51419 14 242 2.4E-41 T 05-07-2017 IPR029066 PLP-binding barrel K08M4_RS10135 418cbb171c7775ee6380a69ba6ce41c8 440 Pfam PF03109 ABC1 family 115 230 1.4E-28 T 05-07-2017 IPR004147 UbiB domain K08M4_RS10135 418cbb171c7775ee6380a69ba6ce41c8 440 SUPERFAMILY SSF56112 98 160 1.48E-14 T 05-07-2017 IPR011009 Protein kinase-like domain K08M4_RS10135 418cbb171c7775ee6380a69ba6ce41c8 440 SUPERFAMILY SSF56112 195 320 1.48E-14 T 05-07-2017 IPR011009 Protein kinase-like domain K08M4_RS03610 1e3fadb2f4aec755a5204cd3183e53b9 373 Pfam PF01098 Cell cycle protein 23 367 3.6E-111 T 05-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 K08M4_RS03610 1e3fadb2f4aec755a5204cd3183e53b9 373 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 324 348 - T 05-07-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 K08M4_RS03610 1e3fadb2f4aec755a5204cd3183e53b9 373 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 20 367 2.9E-132 T 05-07-2017 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 K08M4_RS19525 153a13aabc79e1e442f970940cc9fb66 114 SUPERFAMILY SSF50022 1 108 5.24E-34 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 K08M4_RS19525 153a13aabc79e1e442f970940cc9fb66 114 Gene3D G3DSA:2.102.10.10 2 108 4.8E-38 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 K08M4_RS19525 153a13aabc79e1e442f970940cc9fb66 114 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 3 107 7.0E-32 T 05-07-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 K08M4_RS19525 153a13aabc79e1e442f970940cc9fb66 114 Pfam PF13806 Rieske-like [2Fe-2S] domain 3 106 5.9E-36 T 05-07-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 K08M4_RS07380 cf7b35f93f29e8fe5b2799f1cfe35c42 229 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 25 211 6.0E-10 T 05-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain K08M4_RS07380 cf7b35f93f29e8fe5b2799f1cfe35c42 229 Gene3D G3DSA:3.40.50.300 23 196 8.7E-16 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07380 cf7b35f93f29e8fe5b2799f1cfe35c42 229 SUPERFAMILY SSF52540 23 200 7.71E-19 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11490 c0a67e9da0e8fa18e6882d411edb0cfd 414 TIGRFAM TIGR01937 nqrB: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit 3 408 5.7E-202 T 05-07-2017 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 K08M4_RS11490 c0a67e9da0e8fa18e6882d411edb0cfd 414 Pfam PF03116 NQR2, RnfD, RnfE family 41 406 3.7E-108 T 05-07-2017 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 K08M4_RS11490 c0a67e9da0e8fa18e6882d411edb0cfd 414 Hamap MF_00426 Na(+)-translocating NADH-quinone reductase subunit B [nqrB]. 2 412 36.418 T 05-07-2017 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 K08M4_RS11490 c0a67e9da0e8fa18e6882d411edb0cfd 414 PIRSF PIRSF016055 1 414 1.0E-200 T 05-07-2017 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 K08M4_RS01320 d8529db1f93d76c3814630b8b950eda8 827 SMART SM00267 382 554 1.3E-46 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS01320 d8529db1f93d76c3814630b8b950eda8 827 SMART SM01049 45 164 1.7E-7 T 05-07-2017 IPR033480 Single Cache domain 2 K08M4_RS01320 d8529db1f93d76c3814630b8b950eda8 827 Gene3D G3DSA:3.30.70.270 394 560 1.9E-46 T 05-07-2017 K08M4_RS01320 d8529db1f93d76c3814630b8b950eda8 827 Gene3D G3DSA:3.30.450.20 65 218 1.3E-31 T 05-07-2017 K08M4_RS01320 d8529db1f93d76c3814630b8b950eda8 827 Gene3D G3DSA:3.30.450.20 219 317 8.8E-11 T 05-07-2017 K08M4_RS01320 d8529db1f93d76c3814630b8b950eda8 827 SUPERFAMILY SSF141868 569 814 4.58E-81 T 05-07-2017 IPR001633 EAL domain K08M4_RS01320 d8529db1f93d76c3814630b8b950eda8 827 Pfam PF08269 Cache domain 34 319 4.0E-61 T 05-07-2017 IPR004010 Double Cache domain 2 K08M4_RS01320 d8529db1f93d76c3814630b8b950eda8 827 Pfam PF00990 Diguanylate cyclase, GGDEF domain 393 548 5.1E-40 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS01320 d8529db1f93d76c3814630b8b950eda8 827 Gene3D G3DSA:3.20.20.450 568 814 6.7E-82 T 05-07-2017 IPR001633 EAL domain K08M4_RS01320 d8529db1f93d76c3814630b8b950eda8 827 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 389 551 1.4E-36 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS01320 d8529db1f93d76c3814630b8b950eda8 827 Pfam PF00563 EAL domain 571 805 4.0E-64 T 05-07-2017 IPR001633 EAL domain K08M4_RS01320 d8529db1f93d76c3814630b8b950eda8 827 SMART SM00052 564 810 8.4E-91 T 05-07-2017 IPR001633 EAL domain K08M4_RS01320 d8529db1f93d76c3814630b8b950eda8 827 SUPERFAMILY SSF55073 398 555 1.02E-40 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS06985 34ef0bd1cd2fb0aa6d83dd283bcf74b5 457 Gene3D G3DSA:1.20.1250.20 243 449 9.4E-52 T 05-07-2017 K08M4_RS06985 34ef0bd1cd2fb0aa6d83dd283bcf74b5 457 PIRSF PIRSF002808 5 453 6.7E-169 T 05-07-2017 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 K08M4_RS06985 34ef0bd1cd2fb0aa6d83dd283bcf74b5 457 TIGRFAM TIGR00712 glpT: glycerol-3-phosphate transporter 1 439 4.0E-235 T 05-07-2017 IPR005267 Glycerol-3-phosphate transporter GO:0015169|GO:0015794|GO:0016021 K08M4_RS06985 34ef0bd1cd2fb0aa6d83dd283bcf74b5 457 Pfam PF07690 Major Facilitator Superfamily 34 401 2.4E-51 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS06985 34ef0bd1cd2fb0aa6d83dd283bcf74b5 457 ProSitePatterns PS00942 glpT family of transporters signature. 153 169 - T 05-07-2017 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-3229133|Reactome: R-HSA-70153 K08M4_RS06985 34ef0bd1cd2fb0aa6d83dd283bcf74b5 457 SUPERFAMILY SSF103473 20 450 8.89E-88 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS06985 34ef0bd1cd2fb0aa6d83dd283bcf74b5 457 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 35 418 1.3E-149 T 05-07-2017 K08M4_RS06985 34ef0bd1cd2fb0aa6d83dd283bcf74b5 457 Gene3D G3DSA:1.20.1250.20 23 225 1.0E-52 T 05-07-2017 K08M4_RS00755 cfd76c9d4e8d2dccecd25251383433ba 143 Pfam PF13508 Acetyltransferase (GNAT) domain 36 109 7.0E-9 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS00755 cfd76c9d4e8d2dccecd25251383433ba 143 Gene3D G3DSA:3.40.630.30 32 137 1.2E-13 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS00755 cfd76c9d4e8d2dccecd25251383433ba 143 SUPERFAMILY SSF55729 6 114 5.32E-14 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS09775 8c0c7e98a2effa6db6349d9b93f1b266 94 SUPERFAMILY SSF47729 1 91 2.94E-30 T 05-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 K08M4_RS09775 8c0c7e98a2effa6db6349d9b93f1b266 94 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 1.2E-18 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS09775 8c0c7e98a2effa6db6349d9b93f1b266 94 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 1.2E-18 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS09775 8c0c7e98a2effa6db6349d9b93f1b266 94 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 1.2E-18 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS09775 8c0c7e98a2effa6db6349d9b93f1b266 94 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 92 5.0E-49 T 05-07-2017 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 K08M4_RS09775 8c0c7e98a2effa6db6349d9b93f1b266 94 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 05-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 K08M4_RS09775 8c0c7e98a2effa6db6349d9b93f1b266 94 Gene3D G3DSA:4.10.520.10 1 92 4.4E-35 T 05-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 K08M4_RS09775 8c0c7e98a2effa6db6349d9b93f1b266 94 SMART SM00411 1 91 5.8E-43 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS09775 8c0c7e98a2effa6db6349d9b93f1b266 94 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 30.877 T 05-07-2017 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 K08M4_RS09775 8c0c7e98a2effa6db6349d9b93f1b266 94 Pfam PF00216 Bacterial DNA-binding protein 1 91 9.1E-31 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS16120 c6dd1c6904e5f813d93925239b0430a1 363 SUPERFAMILY SSF111369 52 272 2.09E-25 T 05-07-2017 K08M4_RS16120 c6dd1c6904e5f813d93925239b0430a1 363 Gene3D G3DSA:2.40.50.100 156 187 5.9E-12 T 05-07-2017 K08M4_RS16120 c6dd1c6904e5f813d93925239b0430a1 363 Gene3D G3DSA:2.40.50.100 62 95 5.9E-12 T 05-07-2017 K08M4_RS16120 c6dd1c6904e5f813d93925239b0430a1 363 Pfam PF13533 Biotin-lipoyl like 63 102 2.6E-6 T 05-07-2017 K08M4_RS16120 c6dd1c6904e5f813d93925239b0430a1 363 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 38 356 3.7E-48 T 05-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 Gene3D G3DSA:3.20.20.80 439 518 1.0E-79 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 Gene3D G3DSA:3.20.20.80 569 761 1.0E-79 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 Gene3D G3DSA:3.20.20.80 839 930 1.0E-79 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 Gene3D G3DSA:3.20.20.80 965 990 1.0E-79 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 Gene3D G3DSA:3.20.20.80 799 804 1.0E-79 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 SUPERFAMILY SSF81296 1117 1164 1.38E-5 T 05-07-2017 IPR014756 Immunoglobulin E-set K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 326 410 4.8E-15 T 05-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 SUPERFAMILY SSF49452 36 186 8.83E-28 T 05-07-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 Pfam PF11852 Domain of unknown function (DUF3372) 932 1093 1.9E-62 T 05-07-2017 IPR024561 Alpha-1,6-glucosidases, pullulanase-type, C-terminal K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 SMART SM00642 547 930 1.4E-4 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 Pfam PF03714 Bacterial pullanase-associated domain 65 186 6.6E-18 T 05-07-2017 IPR005323 Bacterial pullanase-associated domain GO:0005975|GO:0030246 K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 Gene3D G3DSA:2.60.40.10 322 425 1.5E-16 T 05-07-2017 IPR013783 Immunoglobulin-like fold K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 SUPERFAMILY SSF51011 993 1107 1.51E-38 T 05-07-2017 K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 SUPERFAMILY SSF51445 422 990 2.99E-127 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 SUPERFAMILY SSF81296 186 311 9.66E-31 T 05-07-2017 IPR014756 Immunoglobulin E-set K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 SUPERFAMILY SSF81296 323 427 9.45E-22 T 05-07-2017 IPR014756 Immunoglobulin E-set K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 Pfam PF00128 Alpha amylase, catalytic domain 601 629 2.1E-4 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS15810 4753653e412906cd9a8b038af7d6ec13 1227 TIGRFAM TIGR02103 pullul_strch: alpha-1,6-glucosidases, pullulanase-type 196 1095 0.0 T 05-07-2017 IPR011839 Alpha-1,6-glucosidases, pullulanase-type GO:0005975|GO:0051060 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 05-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 SUPERFAMILY SSF55729 465 599 4.36E-17 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 Pfam PF14698 Argininosuccinate lyase C-terminal 364 431 1.5E-23 T 05-07-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 Gene3D G3DSA:1.20.200.10 108 374 3.3E-102 T 05-07-2017 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 454 40.684 T 05-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 TIGRFAM TIGR00838 argH: argininosuccinate lyase 3 456 1.3E-203 T 05-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 Gene3D G3DSA:1.10.40.30 375 432 9.9E-30 T 05-07-2017 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 Pfam PF00206 Lyase 6 301 1.6E-87 T 05-07-2017 IPR022761 Fumarate lyase, N-terminal K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 3.7E-28 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 3.7E-28 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 3.7E-28 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 3.7E-28 T 05-07-2017 IPR000362 Fumarate lyase family K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 1.8E-67 T 05-07-2017 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 1.8E-67 T 05-07-2017 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 1.8E-67 T 05-07-2017 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 1.8E-67 T 05-07-2017 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 1.8E-67 T 05-07-2017 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 1.8E-67 T 05-07-2017 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 Gene3D G3DSA:1.10.275.10 1 107 6.1E-36 T 05-07-2017 IPR024083 Fumarase/histidase, N-terminal K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 SUPERFAMILY SSF48557 3 456 1.16E-141 T 05-07-2017 IPR008948 L-Aspartase-like GO:0003824 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 Pfam PF00583 Acetyltransferase (GNAT) family 508 571 9.5E-9 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 PIRSF PIRSF036456 1 624 0.0 T 05-07-2017 IPR011244 Bifunctional argininosuccinate lyase/acetyltransferase GO:0004056|GO:0005737|GO:0006526|GO:0016746 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 K08M4_RS01215 844d1414aceceabc4fa102edb411ab63 624 Gene3D G3DSA:3.40.630.30 464 604 4.3E-29 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS19845 081c2f23f50301941b43ba66d6169196 543 Pfam PF08388 Group II intron, maturase-specific domain 394 469 2.7E-23 T 05-07-2017 IPR013597 Group II intron, maturase-specific K08M4_RS19845 081c2f23f50301941b43ba66d6169196 543 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 113 456 4.0E-109 T 05-07-2017 IPR030931 Group II intron reverse transcriptase/maturase K08M4_RS19845 081c2f23f50301941b43ba66d6169196 543 SUPERFAMILY SSF56672 133 459 8.15E-48 T 05-07-2017 K08M4_RS19845 081c2f23f50301941b43ba66d6169196 543 Pfam PF13655 N-terminal domain of reverse transcriptase 69 150 2.2E-30 T 05-07-2017 IPR025960 Reverse transcriptase, N-terminal domain K08M4_RS19845 081c2f23f50301941b43ba66d6169196 543 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 165 374 1.8E-40 T 05-07-2017 IPR000477 Reverse transcriptase domain K08M4_RS07165 c98745461d0300c041a590fc7ee89cd3 219 SUPERFAMILY SSF52833 9 109 3.47E-16 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS07165 c98745461d0300c041a590fc7ee89cd3 219 Pfam PF13417 Glutathione S-transferase, N-terminal domain 10 82 1.7E-12 T 05-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 K08M4_RS07165 c98745461d0300c041a590fc7ee89cd3 219 Gene3D G3DSA:1.20.1050.10 98 211 3.3E-14 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS07165 c98745461d0300c041a590fc7ee89cd3 219 Pfam PF13410 Glutathione S-transferase, C-terminal domain 129 192 1.2E-12 T 05-07-2017 K08M4_RS07165 c98745461d0300c041a590fc7ee89cd3 219 SUPERFAMILY SSF47616 81 211 5.73E-18 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS07165 c98745461d0300c041a590fc7ee89cd3 219 Gene3D G3DSA:3.40.30.10 8 97 2.5E-20 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS15585 f0d0174588b34bb5fc2ab685cd947a51 99 SUPERFAMILY SSF46785 6 95 8.24E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15585 f0d0174588b34bb5fc2ab685cd947a51 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 4.9E-7 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS15585 f0d0174588b34bb5fc2ab685cd947a51 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 4.9E-7 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS15585 f0d0174588b34bb5fc2ab685cd947a51 99 Gene3D G3DSA:1.10.10.10 6 97 5.6E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15585 f0d0174588b34bb5fc2ab685cd947a51 99 Pfam PF01022 Bacterial regulatory protein, arsR family 21 70 8.9E-12 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS15585 f0d0174588b34bb5fc2ab685cd947a51 99 SMART SM00418 14 99 6.2E-12 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS03285 133f3e33c8f4cd3c5c288c90802b30a8 226 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 38 145 5.3E-8 T 05-07-2017 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 K08M4_RS03285 133f3e33c8f4cd3c5c288c90802b30a8 226 SUPERFAMILY SSF49354 33 144 5.23E-14 T 05-07-2017 IPR008962 PapD-like K08M4_RS03285 133f3e33c8f4cd3c5c288c90802b30a8 226 Gene3D G3DSA:2.60.40.360 38 143 1.6E-6 T 05-07-2017 IPR008962 PapD-like K08M4_RS00645 746b9f25a818155f97e2c63eee12253d 369 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 11 368 2.3E-185 T 05-07-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 K08M4_RS00645 746b9f25a818155f97e2c63eee12253d 369 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 301 330 - T 05-07-2017 IPR030390 RNA methyltransferase TrmA, active site K08M4_RS00645 746b9f25a818155f97e2c63eee12253d 369 TIGRFAM TIGR02143 trmA_only: tRNA (uracil(54)-C(5))-methyltransferase 11 368 2.1E-186 T 05-07-2017 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 K08M4_RS00645 746b9f25a818155f97e2c63eee12253d 369 SUPERFAMILY SSF53335 10 367 4.8E-55 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS00645 746b9f25a818155f97e2c63eee12253d 369 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 350 360 - T 05-07-2017 IPR030391 RNA methyltransferase TrmA, conserved site K08M4_RS00645 746b9f25a818155f97e2c63eee12253d 369 Gene3D G3DSA:3.40.50.150 155 367 4.0E-44 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS00645 746b9f25a818155f97e2c63eee12253d 369 Hamap MF_01011 tRNA/tmRNA (uracil-C(5))-methyltransferase [trmA]. 4 368 44.623 T 05-07-2017 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 K08M4_RS18670 55f1d2271b5f90ec2123589d8a23be32 563 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 164 307 1.0E-17 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain K08M4_RS18670 55f1d2271b5f90ec2123589d8a23be32 563 Gene3D G3DSA:3.40.190.10 267 307 8.4E-8 T 05-07-2017 K08M4_RS18670 55f1d2271b5f90ec2123589d8a23be32 563 Gene3D G3DSA:3.90.76.10 133 266 2.0E-18 T 05-07-2017 K08M4_RS18670 55f1d2271b5f90ec2123589d8a23be32 563 Pfam PF12793 Sugar transport-related sRNA regulator N-term 5 119 1.1E-38 T 05-07-2017 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain K08M4_RS18670 55f1d2271b5f90ec2123589d8a23be32 563 SUPERFAMILY SSF53850 120 558 4.34E-54 T 05-07-2017 K08M4_RS06340 767873b84dafdcc4674167bd153fad64 342 PIRSF PIRSF005632 1 342 4.1E-196 T 05-07-2017 IPR016456 Predicted cobalamin-independent methionine synthase, catalytic subunit K08M4_RS06340 767873b84dafdcc4674167bd153fad64 342 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 5 330 6.4E-38 T 05-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 K08M4_RS06340 767873b84dafdcc4674167bd153fad64 342 SUPERFAMILY SSF51726 7 340 5.36E-70 T 05-07-2017 K08M4_RS06340 767873b84dafdcc4674167bd153fad64 342 Gene3D G3DSA:3.20.20.210 2 340 3.8E-92 T 05-07-2017 K08M4_RS10375 2fead94a7b58c539e222195dc6af011e 90 SUPERFAMILY SSF47729 1 90 2.21E-31 T 05-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 K08M4_RS10375 2fead94a7b58c539e222195dc6af011e 90 Gene3D G3DSA:4.10.520.10 1 90 1.4E-36 T 05-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 K08M4_RS10375 2fead94a7b58c539e222195dc6af011e 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 6.8E-33 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS10375 2fead94a7b58c539e222195dc6af011e 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.5E-20 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS10375 2fead94a7b58c539e222195dc6af011e 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.5E-20 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS10375 2fead94a7b58c539e222195dc6af011e 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.5E-20 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS10375 2fead94a7b58c539e222195dc6af011e 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 05-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 K08M4_RS10375 2fead94a7b58c539e222195dc6af011e 90 SMART SM00411 1 90 2.1E-42 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS04700 f47604e175b6087277c727e2e91c9175 616 Pfam PF01343 Peptidase family S49 138 288 2.4E-29 T 05-07-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 K08M4_RS04700 f47604e175b6087277c727e2e91c9175 616 Pfam PF01343 Peptidase family S49 391 541 2.7E-46 T 05-07-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 K08M4_RS04700 f47604e175b6087277c727e2e91c9175 616 PIRSF PIRSF001217 8 616 1.4E-224 T 05-07-2017 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 K08M4_RS04700 f47604e175b6087277c727e2e91c9175 616 Gene3D G3DSA:3.90.226.10 322 431 2.8E-66 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS04700 f47604e175b6087277c727e2e91c9175 616 Gene3D G3DSA:3.90.226.10 468 553 2.8E-66 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS04700 f47604e175b6087277c727e2e91c9175 616 Gene3D G3DSA:3.90.226.10 29 174 1.4E-58 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS04700 f47604e175b6087277c727e2e91c9175 616 Gene3D G3DSA:3.90.226.10 217 312 1.4E-58 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS04700 f47604e175b6087277c727e2e91c9175 616 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 16 608 5.4E-191 T 05-07-2017 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 K08M4_RS04700 f47604e175b6087277c727e2e91c9175 616 SUPERFAMILY SSF52096 209 284 1.99E-26 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS04700 f47604e175b6087277c727e2e91c9175 616 SUPERFAMILY SSF52096 37 178 1.99E-26 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS04700 f47604e175b6087277c727e2e91c9175 616 SUPERFAMILY SSF52096 467 529 1.95E-43 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS04700 f47604e175b6087277c727e2e91c9175 616 SUPERFAMILY SSF52096 313 439 1.95E-43 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS04700 f47604e175b6087277c727e2e91c9175 616 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 327 539 1.9E-51 T 05-07-2017 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 K08M4_RS10355 8fdc717417634e5d25b6d644b6ab20a2 199 SMART SM01144 1 189 1.0E-71 T 05-07-2017 IPR005636 DTW K08M4_RS10355 8fdc717417634e5d25b6d644b6ab20a2 199 Pfam PF03942 DTW domain 3 184 8.1E-50 T 05-07-2017 IPR005636 DTW K08M4_RS10130 c80ba8d2be1d24fcb89169eb0cffd46e 128 Pfam PF04134 Protein of unknown function, DUF393 6 112 2.8E-25 T 05-07-2017 IPR007263 Protein of unknown function DUF393 K08M4_RS13065 cf92683ef363507b55114a6979a4033b 969 Gene3D G3DSA:3.40.50.300 164 318 5.4E-15 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13065 cf92683ef363507b55114a6979a4033b 969 Pfam PF12137 RNA polymerase recycling family C-terminal 607 966 3.5E-145 T 05-07-2017 IPR022737 RNA polymerase recycling, bacterial, C-terminal GO:0016817 K08M4_RS13065 cf92683ef363507b55114a6979a4033b 969 SMART SM00487 150 342 5.0E-15 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS13065 cf92683ef363507b55114a6979a4033b 969 Pfam PF00176 SNF2 family N-terminal domain 174 344 1.4E-15 T 05-07-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 K08M4_RS13065 cf92683ef363507b55114a6979a4033b 969 SMART SM00490 519 603 6.0E-17 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS13065 cf92683ef363507b55114a6979a4033b 969 Gene3D G3DSA:3.40.50.300 486 604 2.3E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13065 cf92683ef363507b55114a6979a4033b 969 SUPERFAMILY SSF52540 120 377 1.44E-36 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13065 cf92683ef363507b55114a6979a4033b 969 SUPERFAMILY SSF52540 482 647 2.89E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13065 cf92683ef363507b55114a6979a4033b 969 SUPERFAMILY SSF52540 273 337 2.89E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13065 cf92683ef363507b55114a6979a4033b 969 Pfam PF00271 Helicase conserved C-terminal domain 494 603 3.4E-15 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS13065 cf92683ef363507b55114a6979a4033b 969 Hamap MF_01821 RNA polymerase-associated protein RapA [rapA]. 1 967 70.945 T 05-07-2017 IPR023949 RNA polymerase-associated protein RapA GO:0006355 K08M4_RS09050 04fae60200a8671e84fdf4222bd99375 184 Pfam PF08534 Redoxin 47 167 2.4E-14 T 05-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 K08M4_RS09050 04fae60200a8671e84fdf4222bd99375 184 Gene3D G3DSA:3.40.30.10 24 180 2.1E-32 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS09050 04fae60200a8671e84fdf4222bd99375 184 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 16 176 6.8E-43 T 05-07-2017 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 K08M4_RS09050 04fae60200a8671e84fdf4222bd99375 184 SUPERFAMILY SSF52833 60 179 1.5E-30 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS19730 50daac26d2ec8295328de74968255a9d 373 SUPERFAMILY SSF111369 194 298 2.48E-7 T 05-07-2017 K08M4_RS19730 50daac26d2ec8295328de74968255a9d 373 SUPERFAMILY SSF111369 62 110 2.88E-9 T 05-07-2017 K08M4_RS19730 50daac26d2ec8295328de74968255a9d 373 SUPERFAMILY SSF111369 139 185 2.88E-9 T 05-07-2017 K08M4_RS19730 50daac26d2ec8295328de74968255a9d 373 Gene3D G3DSA:2.40.50.100 215 248 5.7E-15 T 05-07-2017 K08M4_RS19730 50daac26d2ec8295328de74968255a9d 373 Gene3D G3DSA:2.40.50.100 63 95 5.7E-15 T 05-07-2017 K08M4_RS19730 50daac26d2ec8295328de74968255a9d 373 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 63 292 3.1E-15 T 05-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain K08M4_RS14915 7895542d04a470a028788a33b65bc63f 288 Gene3D G3DSA:1.10.287.80 203 236 5.6E-39 T 05-07-2017 K08M4_RS14915 7895542d04a470a028788a33b65bc63f 288 Gene3D G3DSA:1.10.287.80 19 60 5.6E-39 T 05-07-2017 K08M4_RS14915 7895542d04a470a028788a33b65bc63f 288 Gene3D G3DSA:3.40.1380.10 63 191 2.0E-44 T 05-07-2017 K08M4_RS14915 7895542d04a470a028788a33b65bc63f 288 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 288 36.552 T 05-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 K08M4_RS14915 7895542d04a470a028788a33b65bc63f 288 Gene3D G3DSA:1.10.287.80 237 283 8.3E-31 T 05-07-2017 K08M4_RS14915 7895542d04a470a028788a33b65bc63f 288 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 274 287 - T 05-07-2017 IPR023632 ATPase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210 K08M4_RS14915 7895542d04a470a028788a33b65bc63f 288 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 288 7.3E-111 T 05-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 K08M4_RS14915 7895542d04a470a028788a33b65bc63f 288 SUPERFAMILY SSF52943 2 288 2.26E-97 T 05-07-2017 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 K08M4_RS14915 7895542d04a470a028788a33b65bc63f 288 Pfam PF00231 ATP synthase 5 287 2.3E-92 T 05-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 K08M4_RS14915 7895542d04a470a028788a33b65bc63f 288 PRINTS PR00126 ATP synthase gamma subunit signature 235 254 1.3E-35 T 05-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 K08M4_RS14915 7895542d04a470a028788a33b65bc63f 288 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 1.3E-35 T 05-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 K08M4_RS14915 7895542d04a470a028788a33b65bc63f 288 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 1.3E-35 T 05-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 K08M4_RS14915 7895542d04a470a028788a33b65bc63f 288 PRINTS PR00126 ATP synthase gamma subunit signature 266 287 1.3E-35 T 05-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 K08M4_RS05895 4d48fff7350189b27ae4e9f6c83c5509 288 Pfam PF03466 LysR substrate binding domain 88 283 4.6E-23 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS05895 4d48fff7350189b27ae4e9f6c83c5509 288 Gene3D G3DSA:3.40.190.10 174 239 8.9E-4 T 05-07-2017 K08M4_RS05895 4d48fff7350189b27ae4e9f6c83c5509 288 SUPERFAMILY SSF53850 89 286 1.3E-25 T 05-07-2017 K08M4_RS05895 4d48fff7350189b27ae4e9f6c83c5509 288 SUPERFAMILY SSF46785 3 112 8.37E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05895 4d48fff7350189b27ae4e9f6c83c5509 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 8.3E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS05895 4d48fff7350189b27ae4e9f6c83c5509 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 8.3E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS05895 4d48fff7350189b27ae4e9f6c83c5509 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 8.3E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS05895 4d48fff7350189b27ae4e9f6c83c5509 288 Gene3D G3DSA:1.10.10.10 3 78 5.9E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05895 4d48fff7350189b27ae4e9f6c83c5509 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 8.0E-18 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS05895 4d48fff7350189b27ae4e9f6c83c5509 288 Gene3D G3DSA:3.40.190.10 92 171 4.9E-10 T 05-07-2017 K08M4_RS20740 f22985a1a173a73dfc4f869cfbcd4fa7 403 Pfam PF07690 Major Facilitator Superfamily 23 356 1.6E-36 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS20740 f22985a1a173a73dfc4f869cfbcd4fa7 403 Gene3D G3DSA:1.20.1250.20 211 390 1.4E-20 T 05-07-2017 K08M4_RS20740 f22985a1a173a73dfc4f869cfbcd4fa7 403 Gene3D G3DSA:1.20.1250.20 9 200 1.5E-23 T 05-07-2017 K08M4_RS20740 f22985a1a173a73dfc4f869cfbcd4fa7 403 SUPERFAMILY SSF103473 5 391 1.01E-57 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS04040 8972f67f1de1940e0aaa922685059025 131 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 5 129 1.9E-29 T 05-07-2017 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 K08M4_RS04040 8972f67f1de1940e0aaa922685059025 131 PIRSF PIRSF002889 1 131 2.7E-33 T 05-07-2017 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 Gene3D G3DSA:3.40.50.300 201 386 1.2E-54 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 Gene3D G3DSA:3.40.50.300 3 167 7.7E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 SMART SM00382 204 347 0.0062 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 SMART SM00382 1 172 6.8 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 SUPERFAMILY SSF52540 181 467 8.29E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 461 1.4E-177 T 05-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 Pfam PF01926 50S ribosome-binding GTPase 208 325 3.5E-24 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 Pfam PF01926 50S ribosome-binding GTPase 5 119 2.1E-27 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 PIRSF PIRSF006485 1 469 5.7E-179 T 05-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 Gene3D G3DSA:3.30.300.20 387 463 1.4E-22 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 SUPERFAMILY SSF52540 4 166 2.79E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 204 370 2.8E-24 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 157 4.4E-21 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 Hamap MF_00195 GTPase Der [der]. 2 464 38.74 T 05-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 381 460 5.4E-25 T 05-07-2017 IPR032859 GTPase Der, C-terminal KH-domain-like K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 6.7E-10 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS11825 7bb9138adacaef17d8920b44fecfa2b7 493 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 72 90 6.7E-10 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS05220 f452b1e4314a6efbd4dd7fd1482ac9fd 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 9.7E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05220 f452b1e4314a6efbd4dd7fd1482ac9fd 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 9.7E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05220 f452b1e4314a6efbd4dd7fd1482ac9fd 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 9.7E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05220 f452b1e4314a6efbd4dd7fd1482ac9fd 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 9.7E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05220 f452b1e4314a6efbd4dd7fd1482ac9fd 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 9.7E-25 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05220 f452b1e4314a6efbd4dd7fd1482ac9fd 246 Pfam PF00106 short chain dehydrogenase 13 208 1.4E-51 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05220 f452b1e4314a6efbd4dd7fd1482ac9fd 246 Gene3D G3DSA:3.40.50.720 8 243 1.6E-66 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS05220 f452b1e4314a6efbd4dd7fd1482ac9fd 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 4.2E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05220 f452b1e4314a6efbd4dd7fd1482ac9fd 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 4.2E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05220 f452b1e4314a6efbd4dd7fd1482ac9fd 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 4.2E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05220 f452b1e4314a6efbd4dd7fd1482ac9fd 246 SUPERFAMILY SSF51735 8 241 3.34E-61 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS05220 f452b1e4314a6efbd4dd7fd1482ac9fd 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 K08M4_RS17410 b514e4c6b09f17de08a19b735f589ed3 270 SUPERFAMILY SSF52096 12 261 2.49E-59 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS17410 b514e4c6b09f17de08a19b735f589ed3 270 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 223 5.3E-32 T 05-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 K08M4_RS17410 b514e4c6b09f17de08a19b735f589ed3 270 Gene3D G3DSA:3.90.226.10 4 253 7.4E-56 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS20820 603e1e9417b75c222635527d07a82037 407 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 194 204 - T 05-07-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 K08M4_RS20820 603e1e9417b75c222635527d07a82037 407 SUPERFAMILY SSF51161 312 393 2.86E-16 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS20820 603e1e9417b75c222635527d07a82037 407 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 10 29 - T 05-07-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 K08M4_RS20820 603e1e9417b75c222635527d07a82037 407 SUPERFAMILY SSF53448 4 275 2.3E-75 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS20820 603e1e9417b75c222635527d07a82037 407 SUPERFAMILY SSF53448 342 358 2.3E-75 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS20820 603e1e9417b75c222635527d07a82037 407 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 96 104 - T 05-07-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 K08M4_RS20820 603e1e9417b75c222635527d07a82037 407 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 5 378 7.3E-149 T 05-07-2017 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 K08M4_RS20820 603e1e9417b75c222635527d07a82037 407 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 1 404 48.836 T 05-07-2017 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 K08M4_RS20820 603e1e9417b75c222635527d07a82037 407 Gene3D G3DSA:3.90.550.10 7 282 3.1E-80 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS20820 603e1e9417b75c222635527d07a82037 407 Gene3D G3DSA:3.90.550.10 325 368 3.1E-80 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS20820 603e1e9417b75c222635527d07a82037 407 Pfam PF00483 Nucleotidyl transferase 6 272 4.6E-67 T 05-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 K08M4_RS02455 a5b573f1fc2607aef4d27e3e9d6ac71c 225 Pfam PF14622 Ribonuclease-III-like 19 140 6.7E-33 T 05-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 K08M4_RS02455 a5b573f1fc2607aef4d27e3e9d6ac71c 225 SMART SM00535 20 148 1.3E-55 T 05-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 K08M4_RS02455 a5b573f1fc2607aef4d27e3e9d6ac71c 225 ProSitePatterns PS00517 Ribonuclease III family signature. 37 45 - T 05-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 K08M4_RS02455 a5b573f1fc2607aef4d27e3e9d6ac71c 225 Gene3D G3DSA:1.10.1520.10 5 146 6.8E-48 T 05-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 K08M4_RS02455 a5b573f1fc2607aef4d27e3e9d6ac71c 225 Gene3D G3DSA:3.30.160.20 152 223 1.0E-27 T 05-07-2017 IPR014720 Double-stranded RNA-binding domain K08M4_RS02455 a5b573f1fc2607aef4d27e3e9d6ac71c 225 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 8 222 5.6E-74 T 05-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 K08M4_RS02455 a5b573f1fc2607aef4d27e3e9d6ac71c 225 SUPERFAMILY SSF69065 5 158 5.23E-51 T 05-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 K08M4_RS02455 a5b573f1fc2607aef4d27e3e9d6ac71c 225 SMART SM00358 155 223 3.9E-23 T 05-07-2017 IPR014720 Double-stranded RNA-binding domain K08M4_RS02455 a5b573f1fc2607aef4d27e3e9d6ac71c 225 SUPERFAMILY SSF54768 108 222 2.67E-28 T 05-07-2017 K08M4_RS02455 a5b573f1fc2607aef4d27e3e9d6ac71c 225 Pfam PF00035 Double-stranded RNA binding motif 155 222 6.4E-16 T 05-07-2017 IPR014720 Double-stranded RNA-binding domain K08M4_RS02455 a5b573f1fc2607aef4d27e3e9d6ac71c 225 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 219 30.109 T 05-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 K08M4_RS12995 3bd28896fcd6ebf191afc25ff74f919d 255 Pfam PF06738 Putative threonine/serine exporter 11 247 1.7E-68 T 05-07-2017 IPR010619 Putative threonine/serine exporter K08M4_RS09245 d588892016c1281a75d1f407f91c8b16 331 Gene3D G3DSA:1.20.970.10 3 67 9.4E-27 T 05-07-2017 K08M4_RS09245 d588892016c1281a75d1f407f91c8b16 331 Pfam PF00591 Glycosyl transferase family, a/b domain 71 321 5.7E-105 T 05-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS09245 d588892016c1281a75d1f407f91c8b16 331 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 62 3.3E-16 T 05-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS09245 d588892016c1281a75d1f407f91c8b16 331 SUPERFAMILY SSF47648 2 67 9.68E-19 T 05-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS09245 d588892016c1281a75d1f407f91c8b16 331 Gene3D G3DSA:3.40.1030.10 70 327 1.1E-102 T 05-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS09245 d588892016c1281a75d1f407f91c8b16 331 SUPERFAMILY SSF52418 69 327 6.28E-94 T 05-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS09245 d588892016c1281a75d1f407f91c8b16 331 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 2 330 39.872 T 05-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 K08M4_RS09245 d588892016c1281a75d1f407f91c8b16 331 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 4 328 8.4E-130 T 05-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 K08M4_RS06890 04834b04c8ab2222406681730cd82654 574 Pfam PF00672 HAMP domain 227 292 5.8E-11 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS06890 04834b04c8ab2222406681730cd82654 574 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 376 571 1.2E-44 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS06890 04834b04c8ab2222406681730cd82654 574 SMART SM00304 243 296 8.3E-7 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS06890 04834b04c8ab2222406681730cd82654 574 SUPERFAMILY SSF58104 264 573 1.83E-67 T 05-07-2017 K08M4_RS06890 04834b04c8ab2222406681730cd82654 574 SMART SM00283 311 572 9.8E-59 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS06890 04834b04c8ab2222406681730cd82654 574 Gene3D G3DSA:1.10.287.950 326 543 3.1E-53 T 05-07-2017 K08M4_RS21715 bedb5b4c20914515a06c22ed65b94602 352 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 250 339 1.3E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21715 bedb5b4c20914515a06c22ed65b94602 352 SMART SM00387 243 341 6.4E-6 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21715 bedb5b4c20914515a06c22ed65b94602 352 Pfam PF06580 Histidine kinase 150 228 2.7E-24 T 05-07-2017 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 K08M4_RS21715 bedb5b4c20914515a06c22ed65b94602 352 Gene3D G3DSA:3.30.565.10 200 340 1.3E-15 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21715 bedb5b4c20914515a06c22ed65b94602 352 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 338 6.7E-6 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS21715 bedb5b4c20914515a06c22ed65b94602 352 PRINTS PR00344 Bacterial sensor protein C-terminal signature 298 316 6.7E-6 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS21715 bedb5b4c20914515a06c22ed65b94602 352 PRINTS PR00344 Bacterial sensor protein C-terminal signature 280 294 6.7E-6 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS21715 bedb5b4c20914515a06c22ed65b94602 352 SUPERFAMILY SSF55874 208 339 7.2E-17 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS06670 089a96e9b7c0960c94bd36f0cb0c39c1 459 Gene3D G3DSA:3.40.50.150 223 318 3.6E-9 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS06670 089a96e9b7c0960c94bd36f0cb0c39c1 459 Pfam PF05971 Protein of unknown function (DUF890) 123 448 6.6E-127 T 05-07-2017 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 K08M4_RS06670 089a96e9b7c0960c94bd36f0cb0c39c1 459 Hamap MF_01848 Ribosomal RNA large subunit methyltransferase F [rlmF]. 122 450 54.489 T 05-07-2017 IPR016909 Ribosomal RNA large subunit methyltransferase F GO:0005737|GO:0006364|GO:0008988 K08M4_RS06670 089a96e9b7c0960c94bd36f0cb0c39c1 459 SUPERFAMILY SSF53335 366 447 6.13E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS06670 089a96e9b7c0960c94bd36f0cb0c39c1 459 SUPERFAMILY SSF53335 161 329 6.13E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS12625 f32833a0b6ee3751d5d2e0cc0f5a5a8d 605 Gene3D G3DSA:3.40.50.2300 261 370 3.9E-50 T 05-07-2017 K08M4_RS12625 f32833a0b6ee3751d5d2e0cc0f5a5a8d 605 Gene3D G3DSA:3.40.50.2300 535 598 3.9E-50 T 05-07-2017 K08M4_RS12625 f32833a0b6ee3751d5d2e0cc0f5a5a8d 605 Pfam PF04348 LppC putative lipoprotein 42 603 4.8E-169 T 05-07-2017 IPR007443 Penicillin-binding protein activator LpoA K08M4_RS12625 f32833a0b6ee3751d5d2e0cc0f5a5a8d 605 SUPERFAMILY SSF53822 265 430 1.41E-68 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS12625 f32833a0b6ee3751d5d2e0cc0f5a5a8d 605 SUPERFAMILY SSF53822 458 602 1.41E-68 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS12625 f32833a0b6ee3751d5d2e0cc0f5a5a8d 605 Gene3D G3DSA:3.40.50.2300 371 534 2.0E-49 T 05-07-2017 K08M4_RS12625 f32833a0b6ee3751d5d2e0cc0f5a5a8d 605 Hamap MF_01890 Penicillin-binding protein activator LpoA [lpoA]. 1 605 28.809 T 05-07-2017 IPR007443 Penicillin-binding protein activator LpoA K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 SUPERFAMILY SSF53850 24 342 1.43E-92 T 05-07-2017 K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 30 46 7.7E-83 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 46 67 7.7E-83 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 245 264 7.7E-83 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 89 102 7.7E-83 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 120 136 7.7E-83 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 146 160 7.7E-83 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 164 183 7.7E-83 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 73 87 7.7E-83 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 290 316 7.7E-83 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 201 220 7.7E-83 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 PIRSF PIRSF019574 1 345 4.5E-122 T 05-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 Gene3D G3DSA:3.40.190.10 131 267 9.8E-23 T 05-07-2017 K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 Gene3D G3DSA:3.40.190.10 268 310 7.7E-62 T 05-07-2017 K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 Gene3D G3DSA:3.40.190.10 23 129 7.7E-62 T 05-07-2017 K08M4_RS07575 2bb4936e3fde05e59a1c9befbba3b072 345 Pfam PF13416 Bacterial extracellular solute-binding protein 40 311 1.1E-41 T 05-07-2017 K08M4_RS08565 cbbb4fc6b398674fe69b7d26d2d73bea 1052 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 568 678 1.4E-6 T 05-07-2017 K08M4_RS08565 cbbb4fc6b398674fe69b7d26d2d73bea 1052 SUPERFAMILY SSF55486 202 353 6.79E-5 T 05-07-2017 K08M4_RS08565 cbbb4fc6b398674fe69b7d26d2d73bea 1052 Gene3D G3DSA:2.60.120.200 566 677 8.1E-9 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain K08M4_RS08565 cbbb4fc6b398674fe69b7d26d2d73bea 1052 SUPERFAMILY SSF49899 564 680 6.24E-12 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain K08M4_RS08565 cbbb4fc6b398674fe69b7d26d2d73bea 1052 SUPERFAMILY SSF49899 711 761 6.24E-12 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain K08M4_RS08565 cbbb4fc6b398674fe69b7d26d2d73bea 1052 Gene3D G3DSA:2.60.120.260 790 845 6.6E-5 T 05-07-2017 IPR008979 Galactose-binding domain-like K08M4_RS21100 bd540b5ee3407d58ea32f2164b77d98a 107 Pfam PF13642 protein structure with unknown function 4 101 7.8E-35 T 05-07-2017 IPR025284 Protein of unknown function DUF4144 K08M4_RS13955 3bdc92f3d59b24b9a14228dc8d9fcdc2 162 SUPERFAMILY SSF52374 1 154 6.7E-42 T 05-07-2017 K08M4_RS13955 3bdc92f3d59b24b9a14228dc8d9fcdc2 162 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 156 7.6E-56 T 05-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 K08M4_RS13955 3bdc92f3d59b24b9a14228dc8d9fcdc2 162 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 110 8.0E-4 T 05-07-2017 K08M4_RS13955 3bdc92f3d59b24b9a14228dc8d9fcdc2 162 Gene3D G3DSA:3.40.50.620 1 157 3.6E-52 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS13955 3bdc92f3d59b24b9a14228dc8d9fcdc2 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 1.3E-47 T 05-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 K08M4_RS13955 3bdc92f3d59b24b9a14228dc8d9fcdc2 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 1.3E-47 T 05-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 K08M4_RS13955 3bdc92f3d59b24b9a14228dc8d9fcdc2 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 1.3E-47 T 05-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 K08M4_RS13955 3bdc92f3d59b24b9a14228dc8d9fcdc2 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 1.3E-47 T 05-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 K08M4_RS13955 3bdc92f3d59b24b9a14228dc8d9fcdc2 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 1.3E-47 T 05-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 K08M4_RS13955 3bdc92f3d59b24b9a14228dc8d9fcdc2 162 Pfam PF01467 Cytidylyltransferase-like 5 133 1.2E-17 T 05-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 K08M4_RS13955 3bdc92f3d59b24b9a14228dc8d9fcdc2 162 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 56 1.2E-15 T 05-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 K08M4_RS13955 3bdc92f3d59b24b9a14228dc8d9fcdc2 162 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 35.002 T 05-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 K08M4_RS09075 993ab3dd01219da6a76ad3579614f403 462 Gene3D G3DSA:1.10.780.10 101 302 2.8E-18 T 05-07-2017 K08M4_RS09075 993ab3dd01219da6a76ad3579614f403 462 TIGRFAM TIGR03152 cyto_c552_HCOOH: formate-dependent cytochrome c nitrite reductase, c552 subunit 22 458 1.5E-246 T 05-07-2017 IPR017570 Formate-dependent cytochrome c nitrite reductase, c552 subunit GO:0005509|GO:0006807|GO:0020037|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 K08M4_RS09075 993ab3dd01219da6a76ad3579614f403 462 Gene3D G3DSA:1.20.140.10 303 429 1.6E-53 T 05-07-2017 K08M4_RS09075 993ab3dd01219da6a76ad3579614f403 462 Pfam PF02335 Cytochrome c552 26 455 7.6E-181 T 05-07-2017 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 K08M4_RS09075 993ab3dd01219da6a76ad3579614f403 462 PIRSF PIRSF000243 3 462 1.1E-126 T 05-07-2017 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 K08M4_RS09075 993ab3dd01219da6a76ad3579614f403 462 SUPERFAMILY SSF48695 22 456 3.0E-162 T 05-07-2017 IPR011031 Multihaem cytochrome K08M4_RS09075 993ab3dd01219da6a76ad3579614f403 462 Hamap MF_01182 Cytochrome c-552 [nrfA]. 1 460 56.774 T 05-07-2017 IPR017570 Formate-dependent cytochrome c nitrite reductase, c552 subunit GO:0005509|GO:0006807|GO:0020037|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 K08M4_RS06255 ad323e895336ad36d7bcf10ec8fe5fc6 371 Pfam PF01926 50S ribosome-binding GTPase 33 136 1.7E-7 T 05-07-2017 IPR006073 GTP binding domain GO:0005525 K08M4_RS06255 ad323e895336ad36d7bcf10ec8fe5fc6 371 Pfam PF05128 Domain of unknown function (DUF697) 220 361 1.7E-6 T 05-07-2017 IPR021147 Protein of unknown function DUF697 K08M4_RS06255 ad323e895336ad36d7bcf10ec8fe5fc6 371 SUPERFAMILY SSF52540 7 145 1.05E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06255 ad323e895336ad36d7bcf10ec8fe5fc6 371 Gene3D G3DSA:3.40.50.300 22 158 5.6E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15080 40d1a5359b366ee273e06f9981d48f73 616 Pfam PF00664 ABC transporter transmembrane region 39 308 5.0E-19 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS15080 40d1a5359b366ee273e06f9981d48f73 616 ProSitePatterns PS00211 ABC transporters family signature. 503 517 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS15080 40d1a5359b366ee273e06f9981d48f73 616 SUPERFAMILY SSF52540 350 601 9.16E-89 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15080 40d1a5359b366ee273e06f9981d48f73 616 SMART SM00382 386 577 9.2E-19 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS15080 40d1a5359b366ee273e06f9981d48f73 616 Gene3D G3DSA:1.20.1560.10 30 330 1.3E-37 T 05-07-2017 K08M4_RS15080 40d1a5359b366ee273e06f9981d48f73 616 Pfam PF00005 ABC transporter 378 531 3.5E-34 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS15080 40d1a5359b366ee273e06f9981d48f73 616 Gene3D G3DSA:3.40.50.300 361 596 1.5E-79 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15080 40d1a5359b366ee273e06f9981d48f73 616 SUPERFAMILY SSF90123 29 346 6.41E-53 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS01630 8f6c3df3c78c5f88f58326b1726a1344 584 SUPERFAMILY SSF69593 46 252 5.49E-12 T 05-07-2017 K08M4_RS01630 8f6c3df3c78c5f88f58326b1726a1344 584 Pfam PF13444 Acetyltransferase (GNAT) domain 329 430 1.5E-18 T 05-07-2017 K08M4_RS01630 8f6c3df3c78c5f88f58326b1726a1344 584 SMART SM00563 74 197 4.4E-9 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 K08M4_RS01630 8f6c3df3c78c5f88f58326b1726a1344 584 SUPERFAMILY SSF55729 312 462 4.03E-21 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS01630 8f6c3df3c78c5f88f58326b1726a1344 584 Gene3D G3DSA:3.40.1130.10 47 194 1.5E-5 T 05-07-2017 K08M4_RS01630 8f6c3df3c78c5f88f58326b1726a1344 584 Pfam PF01553 Acyltransferase 65 194 5.1E-8 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 K08M4_RS01460 c097fcac4f761df4a906a35e0142e922 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 05-07-2017 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01460 c097fcac4f761df4a906a35e0142e922 103 Gene3D G3DSA:3.30.70.600 3 102 1.4E-43 T 05-07-2017 IPR027486 Ribosomal protein S10 domain K08M4_RS01460 c097fcac4f761df4a906a35e0142e922 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 8.6E-46 T 05-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01460 c097fcac4f761df4a906a35e0142e922 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 3.4E-35 T 05-07-2017 IPR027486 Ribosomal protein S10 domain K08M4_RS01460 c097fcac4f761df4a906a35e0142e922 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.066 T 05-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01460 c097fcac4f761df4a906a35e0142e922 103 SUPERFAMILY SSF54999 5 101 1.14E-36 T 05-07-2017 IPR027486 Ribosomal protein S10 domain K08M4_RS01460 c097fcac4f761df4a906a35e0142e922 103 SMART SM01403 7 101 6.0E-56 T 05-07-2017 IPR027486 Ribosomal protein S10 domain K08M4_RS01460 c097fcac4f761df4a906a35e0142e922 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 1.4E-18 T 05-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01460 c097fcac4f761df4a906a35e0142e922 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 1.4E-18 T 05-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01460 c097fcac4f761df4a906a35e0142e922 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.4E-18 T 05-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS21375 52686b4aa2e9daa53a5719a3737783d7 396 SMART SM00267 169 349 4.1E-47 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS21375 52686b4aa2e9daa53a5719a3737783d7 396 SUPERFAMILY SSF55073 185 351 1.33E-41 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS21375 52686b4aa2e9daa53a5719a3737783d7 396 Pfam PF00990 Diguanylate cyclase, GGDEF domain 180 345 2.9E-39 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS21375 52686b4aa2e9daa53a5719a3737783d7 396 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 177 348 8.0E-42 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS21375 52686b4aa2e9daa53a5719a3737783d7 396 Gene3D G3DSA:3.30.70.270 181 352 5.4E-48 T 05-07-2017 K08M4_RS05840 f2150392b2b19c624529daa60b770ac8 412 SUPERFAMILY SSF52540 69 353 5.63E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05840 f2150392b2b19c624529daa60b770ac8 412 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 147 155 - T 05-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site K08M4_RS05840 f2150392b2b19c624529daa60b770ac8 412 Gene3D G3DSA:3.40.50.300 212 366 1.0E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05840 f2150392b2b19c624529daa60b770ac8 412 Pfam PF00270 DEAD/DEAH box helicase 24 186 1.3E-46 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS05840 f2150392b2b19c624529daa60b770ac8 412 Gene3D G3DSA:3.40.50.300 1 211 6.4E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05840 f2150392b2b19c624529daa60b770ac8 412 Pfam PF00271 Helicase conserved C-terminal domain 225 333 5.6E-29 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS05840 f2150392b2b19c624529daa60b770ac8 412 SMART SM00487 19 216 6.4E-48 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS05840 f2150392b2b19c624529daa60b770ac8 412 SMART SM00490 252 333 2.4E-32 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS03560 c4131eb7bbd64f193c2817997df0b895 302 SUPERFAMILY SSF53850 92 296 2.95E-38 T 05-07-2017 K08M4_RS03560 c4131eb7bbd64f193c2817997df0b895 302 Pfam PF03466 LysR substrate binding domain 91 292 1.3E-36 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS03560 c4131eb7bbd64f193c2817997df0b895 302 Gene3D G3DSA:1.10.10.10 1 86 2.5E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS03560 c4131eb7bbd64f193c2817997df0b895 302 Gene3D G3DSA:3.40.190.10 94 179 8.3E-34 T 05-07-2017 K08M4_RS03560 c4131eb7bbd64f193c2817997df0b895 302 Gene3D G3DSA:3.40.190.10 180 259 5.1E-16 T 05-07-2017 K08M4_RS03560 c4131eb7bbd64f193c2817997df0b895 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.8E-9 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS03560 c4131eb7bbd64f193c2817997df0b895 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.8E-9 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS03560 c4131eb7bbd64f193c2817997df0b895 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.8E-9 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS03560 c4131eb7bbd64f193c2817997df0b895 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 2.4E-20 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS03560 c4131eb7bbd64f193c2817997df0b895 302 SUPERFAMILY SSF46785 3 85 6.56E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05295 efd5d646c81acb74982c5f14f63ccb56 268 Gene3D G3DSA:3.60.10.10 1 267 1.1E-87 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS05295 efd5d646c81acb74982c5f14f63ccb56 268 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 267 9.1E-90 T 05-07-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 K08M4_RS05295 efd5d646c81acb74982c5f14f63ccb56 268 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 267 2.9E-102 T 05-07-2017 K08M4_RS05295 efd5d646c81acb74982c5f14f63ccb56 268 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 260 1.0E-25 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS05295 efd5d646c81acb74982c5f14f63ccb56 268 SUPERFAMILY SSF56219 1 268 1.7E-88 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS05295 efd5d646c81acb74982c5f14f63ccb56 268 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 05-07-2017 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 K08M4_RS14765 ebfce7cc62f2e95f4ec6be331265940e 376 Pfam PF02222 ATP-grasp domain 101 274 5.6E-51 T 05-07-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type K08M4_RS14765 ebfce7cc62f2e95f4ec6be331265940e 376 Gene3D G3DSA:3.30.1490.20 107 165 2.7E-21 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 K08M4_RS14765 ebfce7cc62f2e95f4ec6be331265940e 376 SUPERFAMILY SSF51246 298 371 1.1E-18 T 05-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 K08M4_RS14765 ebfce7cc62f2e95f4ec6be331265940e 376 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 2 346 37.174 T 05-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 K08M4_RS14765 ebfce7cc62f2e95f4ec6be331265940e 376 Gene3D G3DSA:3.30.470.20 177 359 3.5E-60 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS14765 ebfce7cc62f2e95f4ec6be331265940e 376 Gene3D G3DSA:3.40.50.20 1 82 8.2E-23 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS14765 ebfce7cc62f2e95f4ec6be331265940e 376 SUPERFAMILY SSF56059 92 295 7.78E-55 T 05-07-2017 K08M4_RS14765 ebfce7cc62f2e95f4ec6be331265940e 376 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 2 350 6.2E-105 T 05-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 K08M4_RS14765 ebfce7cc62f2e95f4ec6be331265940e 376 SUPERFAMILY SSF52440 1 88 4.32E-16 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS13260 ac80d644bb6a5cf478209f21550a4138 246 SUPERFAMILY SSF52540 72 241 5.66E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13260 ac80d644bb6a5cf478209f21550a4138 246 Gene3D G3DSA:3.40.50.300 52 229 2.9E-25 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13260 ac80d644bb6a5cf478209f21550a4138 246 Pfam PF08483 IstB-like ATP binding N-terminal 23 50 9.3E-9 T 05-07-2017 IPR013690 IstB-like ATP binding N-terminal K08M4_RS13260 ac80d644bb6a5cf478209f21550a4138 246 PIRSF PIRSF003073 1 246 1.9E-63 T 05-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein K08M4_RS13260 ac80d644bb6a5cf478209f21550a4138 246 Pfam PF01695 IstB-like ATP binding protein 54 229 4.6E-56 T 05-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 K08M4_RS20510 4e870d9d593760b400953c5a70f647de 430 Pfam PF13416 Bacterial extracellular solute-binding protein 40 351 6.4E-36 T 05-07-2017 K08M4_RS20510 4e870d9d593760b400953c5a70f647de 430 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 137 154 - T 05-07-2017 IPR006061 Solute-binding family 1, conserved site GO:0005215|GO:0006810 K08M4_RS20510 4e870d9d593760b400953c5a70f647de 430 SUPERFAMILY SSF53850 23 417 1.45E-68 T 05-07-2017 K08M4_RS20510 4e870d9d593760b400953c5a70f647de 430 Gene3D G3DSA:3.40.190.10 142 349 1.1E-33 T 05-07-2017 K08M4_RS11930 50cad02eb740d8756916290172e4c0de 109 PRINTS PR01853 Bacterial YajC preprotein translocase signature 19 39 1.0E-15 T 05-07-2017 IPR003849 Preprotein translocase YajC K08M4_RS11930 50cad02eb740d8756916290172e4c0de 109 PRINTS PR01853 Bacterial YajC preprotein translocase signature 57 75 1.0E-15 T 05-07-2017 IPR003849 Preprotein translocase YajC K08M4_RS11930 50cad02eb740d8756916290172e4c0de 109 Pfam PF02699 Preprotein translocase subunit 21 98 1.5E-25 T 05-07-2017 IPR003849 Preprotein translocase YajC K08M4_RS11930 50cad02eb740d8756916290172e4c0de 109 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 19 101 4.2E-30 T 05-07-2017 IPR003849 Preprotein translocase YajC K08M4_RS11930 50cad02eb740d8756916290172e4c0de 109 SMART SM01323 17 101 1.6E-37 T 05-07-2017 IPR003849 Preprotein translocase YajC K08M4_RS13530 58a617a6d4209e77faa8f55f91d95d57 310 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 9 295 7.6E-114 T 05-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 K08M4_RS13530 58a617a6d4209e77faa8f55f91d95d57 310 Gene3D G3DSA:1.10.287.890 203 285 1.7E-33 T 05-07-2017 K08M4_RS13530 58a617a6d4209e77faa8f55f91d95d57 310 SUPERFAMILY SSF52540 10 152 1.41E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13530 58a617a6d4209e77faa8f55f91d95d57 310 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 8 301 30.137 T 05-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 K08M4_RS13530 58a617a6d4209e77faa8f55f91d95d57 310 Pfam PF01715 IPP transferase 42 287 6.7E-86 T 05-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 K08M4_RS13530 58a617a6d4209e77faa8f55f91d95d57 310 Gene3D G3DSA:3.40.50.300 8 174 3.4E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12365 071df122d52d41a6fdb7c32a9c6674e6 421 Hamap MF_00967 ATP-dependent RNA helicase SrmB [srmB]. 3 417 49.081 T 05-07-2017 IPR028621 ATP-dependent RNA helicase SrmB GO:0000027|GO:0004004 K08M4_RS12365 071df122d52d41a6fdb7c32a9c6674e6 421 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 05-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site K08M4_RS12365 071df122d52d41a6fdb7c32a9c6674e6 421 Gene3D G3DSA:3.40.50.300 2 213 1.7E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12365 071df122d52d41a6fdb7c32a9c6674e6 421 Pfam PF00271 Helicase conserved C-terminal domain 234 341 5.3E-31 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS12365 071df122d52d41a6fdb7c32a9c6674e6 421 SMART SM00487 22 224 1.3E-53 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS12365 071df122d52d41a6fdb7c32a9c6674e6 421 Gene3D G3DSA:3.40.50.300 214 372 5.4E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12365 071df122d52d41a6fdb7c32a9c6674e6 421 SMART SM00490 260 341 1.1E-31 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS12365 071df122d52d41a6fdb7c32a9c6674e6 421 Pfam PF00270 DEAD/DEAH box helicase 27 193 1.1E-45 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS12365 071df122d52d41a6fdb7c32a9c6674e6 421 SUPERFAMILY SSF52540 76 359 1.8E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20830 d32589801f16fcc56cd52076b7826984 259 SUPERFAMILY SSF56784 10 255 1.26E-28 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS20830 d32589801f16fcc56cd52076b7826984 259 Pfam PF08282 haloacid dehalogenase-like hydrolase 15 107 2.0E-7 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS20830 d32589801f16fcc56cd52076b7826984 259 Gene3D G3DSA:3.40.50.1000 12 91 1.7E-17 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS20830 d32589801f16fcc56cd52076b7826984 259 Gene3D G3DSA:3.40.50.1000 162 250 1.7E-17 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS20830 d32589801f16fcc56cd52076b7826984 259 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 15 221 3.0E-18 T 05-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 K08M4_RS19660 3efdc03ca6057cc3e22d134b5c32f557 391 Gene3D G3DSA:1.20.1250.20 2 183 9.2E-14 T 05-07-2017 K08M4_RS19660 3efdc03ca6057cc3e22d134b5c32f557 391 Gene3D G3DSA:1.20.1250.20 204 385 1.8E-15 T 05-07-2017 K08M4_RS19660 3efdc03ca6057cc3e22d134b5c32f557 391 Pfam PF07690 Major Facilitator Superfamily 9 244 2.2E-16 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS19660 3efdc03ca6057cc3e22d134b5c32f557 391 SUPERFAMILY SSF103473 2 385 3.01E-41 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS18365 1683563697a925dce7e0adc638d00d6d 549 SUPERFAMILY SSF51905 3 287 2.41E-90 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS18365 1683563697a925dce7e0adc638d00d6d 549 SUPERFAMILY SSF51905 471 533 2.41E-90 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS18365 1683563697a925dce7e0adc638d00d6d 549 PIRSF PIRSF000137 1 540 1.1E-156 T 05-07-2017 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 K08M4_RS18365 1683563697a925dce7e0adc638d00d6d 549 Pfam PF00732 GMC oxidoreductase 4 294 4.9E-92 T 05-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 K08M4_RS18365 1683563697a925dce7e0adc638d00d6d 549 SUPERFAMILY SSF54373 289 472 1.28E-45 T 05-07-2017 K08M4_RS18365 1683563697a925dce7e0adc638d00d6d 549 Pfam PF05199 GMC oxidoreductase 387 523 1.4E-40 T 05-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 K08M4_RS18365 1683563697a925dce7e0adc638d00d6d 549 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 81 104 - T 05-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 K08M4_RS18365 1683563697a925dce7e0adc638d00d6d 549 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 253 267 - T 05-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 K08M4_RS18365 1683563697a925dce7e0adc638d00d6d 549 Gene3D G3DSA:3.50.50.60 465 532 1.3E-125 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS18365 1683563697a925dce7e0adc638d00d6d 549 Gene3D G3DSA:3.50.50.60 186 312 1.3E-125 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS18365 1683563697a925dce7e0adc638d00d6d 549 Gene3D G3DSA:3.50.50.60 2 125 1.3E-125 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS21160 d65ddc9e3745ed0d3e37c9453b19c64f 160 ProSitePatterns PS01117 MarR-type HTH domain signature. 84 118 - T 05-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site K08M4_RS21160 d65ddc9e3745ed0d3e37c9453b19c64f 160 Pfam PF01047 MarR family 52 110 2.9E-14 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS21160 d65ddc9e3745ed0d3e37c9453b19c64f 160 SUPERFAMILY SSF46785 11 158 2.77E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21160 d65ddc9e3745ed0d3e37c9453b19c64f 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 85 2.6E-12 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS21160 d65ddc9e3745ed0d3e37c9453b19c64f 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 135 155 2.6E-12 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS21160 d65ddc9e3745ed0d3e37c9453b19c64f 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 121 2.6E-12 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS21160 d65ddc9e3745ed0d3e37c9453b19c64f 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 101 2.6E-12 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS21160 d65ddc9e3745ed0d3e37c9453b19c64f 160 Gene3D G3DSA:1.10.10.10 8 158 1.9E-35 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21160 d65ddc9e3745ed0d3e37c9453b19c64f 160 SMART SM00347 42 145 2.1E-23 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 SUPERFAMILY SSF52021 4 139 5.49E-58 T 05-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 SMART SM01097 3 133 2.0E-94 T 05-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 380 1.9E-148 T 05-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 PRINTS PR00097 Anthranilate synthase component II signature 241 250 1.7E-5 T 05-07-2017 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 PRINTS PR00097 Anthranilate synthase component II signature 269 280 1.7E-5 T 05-07-2017 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 PRINTS PR00097 Anthranilate synthase component II signature 354 367 1.7E-5 T 05-07-2017 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 SUPERFAMILY SSF52317 158 380 9.94E-62 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 PRINTS PR00096 Glutamine amidotransferase superfamily signature 241 250 6.6E-11 T 05-07-2017 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 PRINTS PR00096 Glutamine amidotransferase superfamily signature 269 280 6.6E-11 T 05-07-2017 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 PRINTS PR00096 Glutamine amidotransferase superfamily signature 354 367 6.6E-11 T 05-07-2017 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 Gene3D G3DSA:3.50.30.20 4 139 1.7E-63 T 05-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 132 6.1E-54 T 05-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 383 48.647 T 05-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 Gene3D G3DSA:3.40.50.880 159 381 6.0E-82 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 238 252 6.7E-40 T 05-07-2017 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 311 322 6.7E-40 T 05-07-2017 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 199 213 6.7E-40 T 05-07-2017 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 286 303 6.7E-40 T 05-07-2017 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 269 285 6.7E-40 T 05-07-2017 K08M4_RS12520 6b55066e826205177d7b5a470e766032 390 Pfam PF00117 Glutamine amidotransferase class-I 202 377 3.1E-47 T 05-07-2017 IPR017926 Glutamine amidotransferase K08M4_RS06750 4467ec0441a146d39126b486997c37e8 142 Pfam PF10980 Protein of unknown function (DUF2787) 32 139 2.3E-28 T 05-07-2017 IPR021248 Protein of unknown function DUF2787 K08M4_RS02355 dc3c29d989cb0e58ea1e92b22d1834cf 409 SUPERFAMILY SSF55021 333 408 9.16E-18 T 05-07-2017 K08M4_RS02355 dc3c29d989cb0e58ea1e92b22d1834cf 409 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 13 326 2.2E-38 T 05-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 K08M4_RS02355 dc3c29d989cb0e58ea1e92b22d1834cf 409 SUPERFAMILY SSF51735 108 295 3.18E-58 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS02355 dc3c29d989cb0e58ea1e92b22d1834cf 409 Gene3D G3DSA:3.40.50.720 120 297 2.0E-63 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS02355 dc3c29d989cb0e58ea1e92b22d1834cf 409 Gene3D G3DSA:3.30.70.260 324 408 1.5E-29 T 05-07-2017 K08M4_RS02355 dc3c29d989cb0e58ea1e92b22d1834cf 409 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 200 222 - T 05-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site K08M4_RS02355 dc3c29d989cb0e58ea1e92b22d1834cf 409 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 294 7.0E-53 T 05-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 K08M4_RS02355 dc3c29d989cb0e58ea1e92b22d1834cf 409 SUPERFAMILY SSF52283 7 136 7.23E-49 T 05-07-2017 K08M4_RS02355 dc3c29d989cb0e58ea1e92b22d1834cf 409 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 154 181 - T 05-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 K08M4_RS02355 dc3c29d989cb0e58ea1e92b22d1834cf 409 Gene3D G3DSA:3.40.50.720 8 119 3.5E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS02355 dc3c29d989cb0e58ea1e92b22d1834cf 409 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 229 245 - T 05-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site K08M4_RS02130 e093432420201ec47a4aa734d75b99d8 199 Pfam PF01725 Ham1 family 4 192 1.6E-56 T 05-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 K08M4_RS02130 e093432420201ec47a4aa734d75b99d8 199 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 193 1.8E-66 T 05-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 K08M4_RS02130 e093432420201ec47a4aa734d75b99d8 199 Gene3D G3DSA:3.90.950.10 1 196 5.7E-81 T 05-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like K08M4_RS02130 e093432420201ec47a4aa734d75b99d8 199 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 196 51.244 T 05-07-2017 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 K08M4_RS02130 e093432420201ec47a4aa734d75b99d8 199 SUPERFAMILY SSF52972 1 196 1.47E-73 T 05-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like K08M4_RS06070 bb86179cc3d5bdae9967db44b97243cb 65 Pfam PF11383 Protein of unknown function (DUF3187) 5 65 1.8E-19 T 05-07-2017 IPR021523 Protein of unknown function DUF3187 K08M4_RS17870 45e7178dd68e2db1c9deda396b27ef7e 380 PRINTS PR00075 Fatty acid desaturase family 1 signature 66 86 7.4E-29 T 05-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 K08M4_RS17870 45e7178dd68e2db1c9deda396b27ef7e 380 PRINTS PR00075 Fatty acid desaturase family 1 signature 104 133 7.4E-29 T 05-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 K08M4_RS17870 45e7178dd68e2db1c9deda396b27ef7e 380 PRINTS PR00075 Fatty acid desaturase family 1 signature 163 181 7.4E-29 T 05-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 K08M4_RS17870 45e7178dd68e2db1c9deda396b27ef7e 380 PRINTS PR00075 Fatty acid desaturase family 1 signature 194 215 7.4E-29 T 05-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 K08M4_RS17870 45e7178dd68e2db1c9deda396b27ef7e 380 PRINTS PR00075 Fatty acid desaturase family 1 signature 237 251 7.4E-29 T 05-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 K08M4_RS17870 45e7178dd68e2db1c9deda396b27ef7e 380 PRINTS PR00075 Fatty acid desaturase family 1 signature 16 36 7.4E-29 T 05-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 K08M4_RS17870 45e7178dd68e2db1c9deda396b27ef7e 380 Pfam PF00487 Fatty acid desaturase 49 268 2.0E-21 T 05-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 K08M4_RS04195 ccd0b48911d6997edcc82912ae256e25 136 PRINTS PR00956 Flagellar motor switch protein FliN signature 73 89 1.4E-27 T 05-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 K08M4_RS04195 ccd0b48911d6997edcc82912ae256e25 136 PRINTS PR00956 Flagellar motor switch protein FliN signature 102 117 1.4E-27 T 05-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 K08M4_RS04195 ccd0b48911d6997edcc82912ae256e25 136 PRINTS PR00956 Flagellar motor switch protein FliN signature 56 72 1.4E-27 T 05-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 K08M4_RS04195 ccd0b48911d6997edcc82912ae256e25 136 PRINTS PR00956 Flagellar motor switch protein FliN signature 89 102 1.4E-27 T 05-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 K08M4_RS04195 ccd0b48911d6997edcc82912ae256e25 136 SUPERFAMILY SSF101801 54 134 7.59E-25 T 05-07-2017 IPR001543 Surface presentation of antigen (SpoA) K08M4_RS04195 ccd0b48911d6997edcc82912ae256e25 136 Gene3D G3DSA:2.30.330.10 47 136 8.1E-38 T 05-07-2017 K08M4_RS04195 ccd0b48911d6997edcc82912ae256e25 136 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 56 126 1.8E-24 T 05-07-2017 IPR001543 Surface presentation of antigen (SpoA) K08M4_RS04195 ccd0b48911d6997edcc82912ae256e25 136 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 54 128 3.2E-33 T 05-07-2017 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 K08M4_RS14345 157b52c1b316d77eb6efaa1c0e4eb74b 185 Pfam PF04220 Der GTPase activator (YihI) 21 175 1.3E-45 T 05-07-2017 IPR007336 Der GTPase activator K08M4_RS14345 157b52c1b316d77eb6efaa1c0e4eb74b 185 Hamap MF_01058 Der GTPase-activating protein YihI [yihI]. 1 178 16.421 T 05-07-2017 IPR007336 Der GTPase activator K08M4_RS16795 ccf66f326808799e1a3719d57ef9a174 110 Pfam PF06296 RelE toxin of RelE / RelB toxin-antitoxin system 4 105 3.1E-10 T 05-07-2017 IPR009387 Toxin HigB-2 K08M4_RS16795 ccf66f326808799e1a3719d57ef9a174 110 PIRSF PIRSF039032 1 110 1.7E-45 T 05-07-2017 IPR009387 Toxin HigB-2 K08M4_RS20375 742735b7e1585340841871f6f15e2704 687 Pfam PF11412 Disulphide bond corrector protein DsbC 49 153 4.0E-16 T 05-07-2017 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain K08M4_RS20375 742735b7e1585340841871f6f15e2704 687 Gene3D G3DSA:3.40.30.10 573 663 7.4E-11 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS20375 742735b7e1585340841871f6f15e2704 687 Pfam PF13899 Thioredoxin-like 582 662 2.1E-10 T 05-07-2017 K08M4_RS20375 742735b7e1585340841871f6f15e2704 687 SUPERFAMILY SSF52833 570 667 3.74E-12 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS14285 0fcfb610a3ecaeaac8c0cbe0b1619bcf 313 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 22 279 1.4E-79 T 05-07-2017 IPR017039 Virulence factor BrkB K08M4_RS14285 0fcfb610a3ecaeaac8c0cbe0b1619bcf 313 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 20 292 23.262 T 05-07-2017 IPR023679 Uncharacterised protein family UPF0761, bacterial K08M4_RS14285 0fcfb610a3ecaeaac8c0cbe0b1619bcf 313 Pfam PF03631 Virulence factor BrkB 33 279 6.7E-55 T 05-07-2017 IPR017039 Virulence factor BrkB K08M4_RS14285 0fcfb610a3ecaeaac8c0cbe0b1619bcf 313 PIRSF PIRSF035875 8 298 5.9E-50 T 05-07-2017 IPR017039 Virulence factor BrkB K08M4_RS01390 a6c6dea004ec028a9dd738b49cbdd7ae 66 Pfam PF09526 Probable metal-binding protein (DUF2387) 4 56 1.2E-20 T 05-07-2017 IPR012658 Conserved hypothetical protein CHP02443 K08M4_RS01390 a6c6dea004ec028a9dd738b49cbdd7ae 66 TIGRFAM TIGR02443 TIGR02443: conserved hypothetical protein 2 60 7.7E-32 T 05-07-2017 IPR012658 Conserved hypothetical protein CHP02443 K08M4_RS15540 3e7d911f987cbd2775f0874edb974b48 702 Gene3D G3DSA:3.90.70.10 6 106 3.4E-15 T 05-07-2017 K08M4_RS15540 3e7d911f987cbd2775f0874edb974b48 702 SUPERFAMILY SSF52540 455 700 1.71E-88 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15540 3e7d911f987cbd2775f0874edb974b48 702 SUPERFAMILY SSF90123 137 448 9.94E-67 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS15540 3e7d911f987cbd2775f0874edb974b48 702 TIGRFAM TIGR01846 type_I_sec_HlyB: type I secretion system ATPase 9 701 0.0 T 05-07-2017 IPR010132 ATPase, type I secretion system, HlyB GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 K08M4_RS15540 3e7d911f987cbd2775f0874edb974b48 702 Gene3D G3DSA:3.40.50.300 464 695 2.0E-79 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15540 3e7d911f987cbd2775f0874edb974b48 702 SMART SM00382 490 676 1.1E-19 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS15540 3e7d911f987cbd2775f0874edb974b48 702 Gene3D G3DSA:1.20.1560.10 137 448 2.2E-75 T 05-07-2017 K08M4_RS15540 3e7d911f987cbd2775f0874edb974b48 702 Pfam PF00664 ABC transporter transmembrane region 153 419 2.3E-45 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS15540 3e7d911f987cbd2775f0874edb974b48 702 Pfam PF00005 ABC transporter 481 630 2.3E-33 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS15540 3e7d911f987cbd2775f0874edb974b48 702 Pfam PF03412 Peptidase C39 family 17 114 6.5E-7 T 05-07-2017 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 K08M4_RS15540 3e7d911f987cbd2775f0874edb974b48 702 ProSitePatterns PS00211 ABC transporters family signature. 602 616 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS11975 b6cb13112e0e193d31224295b668751d 301 Gene3D G3DSA:1.10.10.10 6 84 4.3E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS11975 b6cb13112e0e193d31224295b668751d 301 Pfam PF03466 LysR substrate binding domain 96 299 1.2E-37 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS11975 b6cb13112e0e193d31224295b668751d 301 Gene3D G3DSA:3.40.190.10 96 196 1.9E-24 T 05-07-2017 K08M4_RS11975 b6cb13112e0e193d31224295b668751d 301 Gene3D G3DSA:3.40.190.10 197 274 6.4E-19 T 05-07-2017 K08M4_RS11975 b6cb13112e0e193d31224295b668751d 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 68 1.2E-15 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS11975 b6cb13112e0e193d31224295b668751d 301 SUPERFAMILY SSF53850 96 300 1.42E-34 T 05-07-2017 K08M4_RS11975 b6cb13112e0e193d31224295b668751d 301 SUPERFAMILY SSF46785 4 117 1.78E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS13980 913f15480646f3ccecb8526b7e76aeca 246 Pfam PF01755 Glycosyltransferase family 25 (LPS biosynthesis protein) 1 116 2.2E-13 T 05-07-2017 IPR002654 Glycosyl transferase, family 25 K08M4_RS19650 d6d0abea51a0b5d9ce029f49ed245c97 518 Pfam PF11230 Protein of unknown function (DUF3029) 26 507 1.7E-232 T 05-07-2017 IPR016905 Glycyl radical enzyme, HI0521, predicted K08M4_RS19650 d6d0abea51a0b5d9ce029f49ed245c97 518 Gene3D G3DSA:3.20.70.20 94 478 3.7E-11 T 05-07-2017 K08M4_RS19650 d6d0abea51a0b5d9ce029f49ed245c97 518 PIRSF PIRSF028991 10 518 2.7E-283 T 05-07-2017 IPR016905 Glycyl radical enzyme, HI0521, predicted K08M4_RS19650 d6d0abea51a0b5d9ce029f49ed245c97 518 TIGRFAM TIGR04040 glycyl_YjjI: glycine radical enzyme, YjjI family 16 507 1.3E-234 T 05-07-2017 IPR016905 Glycyl radical enzyme, HI0521, predicted K08M4_RS19650 d6d0abea51a0b5d9ce029f49ed245c97 518 SUPERFAMILY SSF51998 24 473 1.83E-95 T 05-07-2017 K08M4_RS01515 a569897c179a9d7ede2f0a7d1a4e6936 123 SMART SM01374 1 123 1.8E-85 T 05-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 K08M4_RS01515 a569897c179a9d7ede2f0a7d1a4e6936 123 Pfam PF00238 Ribosomal protein L14p/L23e 1 123 2.0E-54 T 05-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 K08M4_RS01515 a569897c179a9d7ede2f0a7d1a4e6936 123 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 123 28.366 T 05-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 K08M4_RS01515 a569897c179a9d7ede2f0a7d1a4e6936 123 Gene3D G3DSA:2.40.150.20 1 123 1.5E-54 T 05-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 K08M4_RS01515 a569897c179a9d7ede2f0a7d1a4e6936 123 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 05-07-2017 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01515 a569897c179a9d7ede2f0a7d1a4e6936 123 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 123 7.1E-59 T 05-07-2017 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 K08M4_RS01515 a569897c179a9d7ede2f0a7d1a4e6936 123 SUPERFAMILY SSF50193 2 122 3.27E-51 T 05-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 K08M4_RS08440 aa926a813af3ac62d3c49dc995fadbc9 195 SUPERFAMILY SSF55729 10 185 7.48E-38 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS08440 aa926a813af3ac62d3c49dc995fadbc9 195 Gene3D G3DSA:3.40.630.30 14 185 1.0E-39 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS08440 aa926a813af3ac62d3c49dc995fadbc9 195 Pfam PF13302 Acetyltransferase (GNAT) domain 17 160 1.9E-18 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS03785 a93ee2a2ee7e1d0810004aca3186620f 196 SUPERFAMILY SSF53178 5 194 2.62E-68 T 05-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 K08M4_RS03785 a93ee2a2ee7e1d0810004aca3186620f 196 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 18 31 - T 05-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 K08M4_RS03785 a93ee2a2ee7e1d0810004aca3186620f 196 Pfam PF01195 Peptidyl-tRNA hydrolase 7 189 1.7E-52 T 05-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 K08M4_RS03785 a93ee2a2ee7e1d0810004aca3186620f 196 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 5 184 35.447 T 05-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 K08M4_RS03785 a93ee2a2ee7e1d0810004aca3186620f 196 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 5 191 6.4E-67 T 05-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 K08M4_RS03785 a93ee2a2ee7e1d0810004aca3186620f 196 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 112 122 - T 05-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 K08M4_RS03785 a93ee2a2ee7e1d0810004aca3186620f 196 Gene3D G3DSA:3.40.50.1470 3 193 1.2E-69 T 05-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 K08M4_RS17295 b35ebf99ef9b26c31f336aebfe8f8043 417 Pfam PF00092 von Willebrand factor type A domain 255 335 1.5E-5 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS17295 b35ebf99ef9b26c31f336aebfe8f8043 417 Gene3D G3DSA:3.40.50.410 127 188 2.0E-13 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS17295 b35ebf99ef9b26c31f336aebfe8f8043 417 Gene3D G3DSA:3.40.50.410 265 342 2.0E-13 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS17295 b35ebf99ef9b26c31f336aebfe8f8043 417 SUPERFAMILY SSF53300 127 183 3.97E-14 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS17295 b35ebf99ef9b26c31f336aebfe8f8043 417 SUPERFAMILY SSF53300 260 408 3.97E-14 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS16275 213f7ea85b45ae7c666432c8ebb055e0 52 Pfam PF01679 Proteolipid membrane potential modulator 4 49 3.3E-18 T 05-07-2017 IPR000612 Proteolipid membrane potential modulator GO:0016021 K08M4_RS16275 213f7ea85b45ae7c666432c8ebb055e0 52 ProSitePatterns PS01309 Uncharacterized protein family UPF0057 signature. 8 23 - T 05-07-2017 IPR000612 Proteolipid membrane potential modulator GO:0016021 K08M4_RS17765 9b56b723ed7f630cece79aa74cce6256 227 Pfam PF06468 Spondin_N 40 157 1.7E-9 T 05-07-2017 IPR009465 Spondin, N-terminal Reactome: R-HSA-5083635|Reactome: R-HSA-5173214 K08M4_RS07230 7d18d7ae2c36b1c8cc06200776532deb 435 SMART SM00901 173 273 1.6E-28 T 05-07-2017 IPR014966 FRG domain K08M4_RS07230 7d18d7ae2c36b1c8cc06200776532deb 435 Pfam PF08867 FRG domain 176 266 2.0E-19 T 05-07-2017 IPR014966 FRG domain K08M4_RS04660 846449273caf63980766005765b276ba 271 Pfam PF13847 Methyltransferase domain 88 222 7.8E-12 T 05-07-2017 IPR025714 Methyltransferase domain K08M4_RS04660 846449273caf63980766005765b276ba 271 SUPERFAMILY SSF53335 4 253 3.68E-43 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS04660 846449273caf63980766005765b276ba 271 Gene3D G3DSA:3.40.50.150 63 183 8.7E-20 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS04660 846449273caf63980766005765b276ba 271 PIRSF PIRSF018249 1 270 1.7E-83 T 05-07-2017 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 K08M4_RS11235 8051199aab06ac5349cda1ab96a047f5 292 Hamap MF_01974 Methionine aminopeptidase [map]. 3 280 39.586 T 05-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 K08M4_RS11235 8051199aab06ac5349cda1ab96a047f5 292 Gene3D G3DSA:3.90.230.10 4 288 1.5E-92 T 05-07-2017 IPR000994 Peptidase M24, structural domain K08M4_RS11235 8051199aab06ac5349cda1ab96a047f5 292 SUPERFAMILY SSF55920 4 282 5.1E-80 T 05-07-2017 IPR000994 Peptidase M24, structural domain K08M4_RS11235 8051199aab06ac5349cda1ab96a047f5 292 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 279 2.0E-81 T 05-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 K08M4_RS11235 8051199aab06ac5349cda1ab96a047f5 292 Pfam PF00557 Metallopeptidase family M24 12 271 6.7E-46 T 05-07-2017 IPR000994 Peptidase M24, structural domain K08M4_RS11235 8051199aab06ac5349cda1ab96a047f5 292 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 197 215 - T 05-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 K08M4_RS11610 03f800e0bb9139e774ce77f47f82e6d5 230 Gene3D G3DSA:3.90.1010.10 177 214 1.8E-19 T 05-07-2017 K08M4_RS11610 03f800e0bb9139e774ce77f47f82e6d5 230 Gene3D G3DSA:3.90.1010.10 30 101 1.8E-19 T 05-07-2017 K08M4_RS11610 03f800e0bb9139e774ce77f47f82e6d5 230 SUPERFAMILY SSF82649 56 101 2.15E-7 T 05-07-2017 K08M4_RS11610 03f800e0bb9139e774ce77f47f82e6d5 230 Pfam PF01592 NifU-like N terminal domain 56 102 2.3E-4 T 05-07-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 K08M4_RS05815 f0bcd0778616292369c3fb862c3b69bc 388 Gene3D G3DSA:3.40.190.10 322 362 4.0E-20 T 05-07-2017 K08M4_RS05815 f0bcd0778616292369c3fb862c3b69bc 388 Gene3D G3DSA:3.40.190.10 39 159 4.0E-20 T 05-07-2017 K08M4_RS05815 f0bcd0778616292369c3fb862c3b69bc 388 SUPERFAMILY SSF53850 40 386 2.98E-40 T 05-07-2017 K08M4_RS05815 f0bcd0778616292369c3fb862c3b69bc 388 Pfam PF13416 Bacterial extracellular solute-binding protein 63 361 1.8E-25 T 05-07-2017 K08M4_RS05815 f0bcd0778616292369c3fb862c3b69bc 388 PIRSF PIRSF029172 1 388 1.3E-172 T 05-07-2017 IPR027020 Protein ynjB K08M4_RS05815 f0bcd0778616292369c3fb862c3b69bc 388 Gene3D G3DSA:3.40.190.10 161 321 2.2E-10 T 05-07-2017 K08M4_RS19780 959f47757585ee61335bc9c6d2e923be 318 Gene3D G3DSA:3.40.190.10 115 191 1.8E-11 T 05-07-2017 K08M4_RS19780 959f47757585ee61335bc9c6d2e923be 318 SUPERFAMILY SSF53850 31 313 8.23E-51 T 05-07-2017 K08M4_RS19780 959f47757585ee61335bc9c6d2e923be 318 Pfam PF09084 NMT1/THI5 like 39 251 1.3E-68 T 05-07-2017 IPR015168 SsuA/THI5-like K08M4_RS10090 4900e6fce8d9d8909a816befecc5ce43 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 11 27 6.2E-14 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS10090 4900e6fce8d9d8909a816befecc5ce43 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 38 6.2E-14 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS10090 4900e6fce8d9d8909a816befecc5ce43 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 57 6.2E-14 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS10090 4900e6fce8d9d8909a816befecc5ce43 161 Pfam PF01037 Lrp/AsnC ligand binding domain 79 149 2.3E-9 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS10090 4900e6fce8d9d8909a816befecc5ce43 161 Pfam PF13404 AsnC-type helix-turn-helix domain 11 52 4.0E-18 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS10090 4900e6fce8d9d8909a816befecc5ce43 161 Gene3D G3DSA:1.10.10.10 12 62 1.8E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS10090 4900e6fce8d9d8909a816befecc5ce43 161 SUPERFAMILY SSF46785 10 70 6.02E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS10090 4900e6fce8d9d8909a816befecc5ce43 161 SUPERFAMILY SSF54909 71 159 1.88E-13 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel K08M4_RS10090 4900e6fce8d9d8909a816befecc5ce43 161 SMART SM00344 11 120 1.5E-32 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 K08M4_RS10090 4900e6fce8d9d8909a816befecc5ce43 161 Gene3D G3DSA:3.30.70.920 64 159 7.4E-17 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS15885 e53253ca238af1d00a935b16d87bcf66 726 SUPERFAMILY SSF81296 138 193 2.66E-6 T 05-07-2017 IPR014756 Immunoglobulin E-set K08M4_RS15885 e53253ca238af1d00a935b16d87bcf66 726 Pfam PF00128 Alpha amylase, catalytic domain 275 348 7.9E-7 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS15885 e53253ca238af1d00a935b16d87bcf66 726 SUPERFAMILY SSF81296 21 102 3.0E-11 T 05-07-2017 IPR014756 Immunoglobulin E-set K08M4_RS15885 e53253ca238af1d00a935b16d87bcf66 726 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 133 207 4.3E-19 T 05-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 K08M4_RS15885 e53253ca238af1d00a935b16d87bcf66 726 Gene3D G3DSA:2.60.40.10 115 222 1.7E-28 T 05-07-2017 IPR013783 Immunoglobulin-like fold K08M4_RS15885 e53253ca238af1d00a935b16d87bcf66 726 Gene3D G3DSA:2.60.40.10 17 101 7.8E-10 T 05-07-2017 IPR013783 Immunoglobulin-like fold K08M4_RS15885 e53253ca238af1d00a935b16d87bcf66 726 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 628 725 1.1E-16 T 05-07-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 K08M4_RS15885 e53253ca238af1d00a935b16d87bcf66 726 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 115 723 1.9E-245 T 05-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 K08M4_RS15885 e53253ca238af1d00a935b16d87bcf66 726 SUPERFAMILY SSF51445 179 616 3.63E-108 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS15885 e53253ca238af1d00a935b16d87bcf66 726 PIRSF PIRSF000463 9 726 6.3E-279 T 05-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 K08M4_RS15885 e53253ca238af1d00a935b16d87bcf66 726 SUPERFAMILY SSF51011 623 725 3.15E-26 T 05-07-2017 K08M4_RS15885 e53253ca238af1d00a935b16d87bcf66 726 Gene3D G3DSA:3.20.20.80 233 611 5.7E-90 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS15885 e53253ca238af1d00a935b16d87bcf66 726 SMART SM00642 250 595 3.1E-6 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS15885 e53253ca238af1d00a935b16d87bcf66 726 Gene3D G3DSA:2.60.40.1180 623 725 1.1E-28 T 05-07-2017 IPR013780 Glycosyl hydrolase, all-beta K08M4_RS15885 e53253ca238af1d00a935b16d87bcf66 726 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 91 726 41.042 T 05-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 K08M4_RS18295 099fad9f1f69f35e02d87d949f4fb28c 311 PRINTS PR00691 Adhesin B signature 237 254 2.9E-9 T 05-07-2017 IPR006129 Adhesin B GO:0007155 K08M4_RS18295 099fad9f1f69f35e02d87d949f4fb28c 311 PRINTS PR00691 Adhesin B signature 30 51 2.9E-9 T 05-07-2017 IPR006129 Adhesin B GO:0007155 K08M4_RS18295 099fad9f1f69f35e02d87d949f4fb28c 311 PRINTS PR00691 Adhesin B signature 130 149 2.9E-9 T 05-07-2017 IPR006129 Adhesin B GO:0007155 K08M4_RS18295 099fad9f1f69f35e02d87d949f4fb28c 311 PRINTS PR00691 Adhesin B signature 55 73 2.9E-9 T 05-07-2017 IPR006129 Adhesin B GO:0007155 K08M4_RS18295 099fad9f1f69f35e02d87d949f4fb28c 311 PRINTS PR00691 Adhesin B signature 74 93 2.9E-9 T 05-07-2017 IPR006129 Adhesin B GO:0007155 K08M4_RS18295 099fad9f1f69f35e02d87d949f4fb28c 311 Pfam PF01297 Zinc-uptake complex component A periplasmic 36 296 3.3E-44 T 05-07-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 K08M4_RS18295 099fad9f1f69f35e02d87d949f4fb28c 311 Gene3D G3DSA:3.40.50.1980 193 299 1.8E-23 T 05-07-2017 K08M4_RS18295 099fad9f1f69f35e02d87d949f4fb28c 311 Gene3D G3DSA:3.40.50.1980 27 180 7.2E-35 T 05-07-2017 K08M4_RS18295 099fad9f1f69f35e02d87d949f4fb28c 311 PRINTS PR00690 Adhesin family signature 241 259 1.3E-7 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 K08M4_RS18295 099fad9f1f69f35e02d87d949f4fb28c 311 PRINTS PR00690 Adhesin family signature 188 209 1.3E-7 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 K08M4_RS18295 099fad9f1f69f35e02d87d949f4fb28c 311 PRINTS PR00690 Adhesin family signature 74 91 1.3E-7 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 K08M4_RS18295 099fad9f1f69f35e02d87d949f4fb28c 311 PRINTS PR00690 Adhesin family signature 61 74 1.3E-7 T 05-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 K08M4_RS18295 099fad9f1f69f35e02d87d949f4fb28c 311 SUPERFAMILY SSF53807 29 299 9.81E-62 T 05-07-2017 K08M4_RS08510 688b4f9dd427e1ddd6a90450caa4d80b 120 Gene3D G3DSA:3.30.479.10 2 120 2.6E-41 T 05-07-2017 K08M4_RS08510 688b4f9dd427e1ddd6a90450caa4d80b 120 SUPERFAMILY SSF55620 3 119 2.0E-41 T 05-07-2017 K08M4_RS08510 688b4f9dd427e1ddd6a90450caa4d80b 120 PIRSF PIRSF006113 1 120 6.8E-53 T 05-07-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 K08M4_RS08510 688b4f9dd427e1ddd6a90450caa4d80b 120 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 4 96 4.3E-33 T 05-07-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 K08M4_RS08510 688b4f9dd427e1ddd6a90450caa4d80b 120 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 5 120 1.4E-35 T 05-07-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 K08M4_RS15590 33b2795e2ddebfcf3317750c8b10a94c 174 Pfam PF04982 HPP family 46 165 4.9E-39 T 05-07-2017 IPR007065 HPP K08M4_RS01375 6eca02824269a778b6025d97050222b6 640 Pfam PF12848 ABC transporter 217 293 3.8E-27 T 05-07-2017 IPR032781 ABC-transporter extension domain K08M4_RS01375 6eca02824269a778b6025d97050222b6 640 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS01375 6eca02824269a778b6025d97050222b6 640 SUPERFAMILY SSF52540 119 257 1.62E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01375 6eca02824269a778b6025d97050222b6 640 SUPERFAMILY SSF52540 2 92 1.62E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01375 6eca02824269a778b6025d97050222b6 640 Pfam PF00005 ABC transporter 328 459 6.4E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS01375 6eca02824269a778b6025d97050222b6 640 Pfam PF00005 ABC transporter 17 178 1.7E-21 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS01375 6eca02824269a778b6025d97050222b6 640 SUPERFAMILY SSF52540 277 494 4.3E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01375 6eca02824269a778b6025d97050222b6 640 Gene3D G3DSA:3.40.50.300 310 539 1.3E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01375 6eca02824269a778b6025d97050222b6 640 Gene3D G3DSA:3.40.50.300 2 274 3.7E-45 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01375 6eca02824269a778b6025d97050222b6 640 SMART SM00382 26 223 3.3E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS01375 6eca02824269a778b6025d97050222b6 640 SMART SM00382 337 503 1.1E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS01375 6eca02824269a778b6025d97050222b6 640 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS10175 7a999cb5bbb5bb0469b7c3b6005329d3 110 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 2 98 1.7E-24 T 05-07-2017 IPR008407 Branched-chain amino acid transport, AzlD K08M4_RS06250 b326f90028b3b2394c926f6c1a5ef49d 170 Gene3D G3DSA:3.30.1060.10 1 159 5.9E-41 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS06250 b326f90028b3b2394c926f6c1a5ef49d 170 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 161 24.1 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS06250 b326f90028b3b2394c926f6c1a5ef49d 170 SUPERFAMILY SSF55068 1 159 7.85E-42 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS06250 b326f90028b3b2394c926f6c1a5ef49d 170 Pfam PF01625 Peptide methionine sulfoxide reductase 3 153 1.7E-41 T 05-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 K08M4_RS13730 97f2c7d2907e5467f012428dfba4c4d5 447 PIRSF PIRSF006603 1 446 1.1E-128 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS13730 97f2c7d2907e5467f012428dfba4c4d5 447 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 409 2.2E-54 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS13730 97f2c7d2907e5467f012428dfba4c4d5 447 Pfam PF01554 MatE 22 181 2.8E-26 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS13730 97f2c7d2907e5467f012428dfba4c4d5 447 Pfam PF01554 MatE 245 406 3.0E-23 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS12505 0b40eba664a38ccc8fb4e95c7e8f033d 281 Pfam PF03466 LysR substrate binding domain 91 276 1.9E-13 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS12505 0b40eba664a38ccc8fb4e95c7e8f033d 281 Gene3D G3DSA:3.40.190.10 95 168 6.2E-5 T 05-07-2017 K08M4_RS12505 0b40eba664a38ccc8fb4e95c7e8f033d 281 SUPERFAMILY SSF53850 90 279 2.9E-18 T 05-07-2017 K08M4_RS12505 0b40eba664a38ccc8fb4e95c7e8f033d 281 SUPERFAMILY SSF46785 4 86 1.86E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS12505 0b40eba664a38ccc8fb4e95c7e8f033d 281 Gene3D G3DSA:1.10.10.10 4 79 4.6E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS12505 0b40eba664a38ccc8fb4e95c7e8f033d 281 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 60 9.1E-13 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS14145 84861a57361b4256f05c471c3b633f8b 431 SMART SM00388 222 282 2.8E-9 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS14145 84861a57361b4256f05c471c3b633f8b 431 Pfam PF00672 HAMP domain 153 217 8.1E-14 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS14145 84861a57361b4256f05c471c3b633f8b 431 SUPERFAMILY SSF158472 171 219 8.63E-6 T 05-07-2017 K08M4_RS14145 84861a57361b4256f05c471c3b633f8b 431 Gene3D G3DSA:1.10.287.130 213 276 5.5E-19 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS14145 84861a57361b4256f05c471c3b633f8b 431 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 322 429 1.6E-21 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS14145 84861a57361b4256f05c471c3b633f8b 431 SUPERFAMILY SSF55874 290 430 8.91E-34 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS14145 84861a57361b4256f05c471c3b633f8b 431 SUPERFAMILY SSF47384 215 277 5.49E-12 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS14145 84861a57361b4256f05c471c3b633f8b 431 SMART SM00387 321 431 1.1E-32 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS14145 84861a57361b4256f05c471c3b633f8b 431 SMART SM00304 169 221 2.4E-10 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS14145 84861a57361b4256f05c471c3b633f8b 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 409 1.6E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS14145 84861a57361b4256f05c471c3b633f8b 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 372 1.6E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS14145 84861a57361b4256f05c471c3b633f8b 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 386 1.6E-13 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS14145 84861a57361b4256f05c471c3b633f8b 431 Pfam PF00512 His Kinase A (phospho-acceptor) domain 225 276 2.6E-9 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS14145 84861a57361b4256f05c471c3b633f8b 431 Gene3D G3DSA:3.30.565.10 290 430 3.3E-34 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS18735 07059f7816ea2c2c1997acc7710bf5ea 532 TIGRFAM TIGR03801 asp_4_decarbox: aspartate 4-decarboxylase 16 528 4.6E-216 T 05-07-2017 IPR022518 Aspartate 4-decarboxylase KEGG: 00220+2.6.1.1|KEGG: 00250+4.1.1.12+2.6.1.1|KEGG: 00270+4.1.1.12+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 K08M4_RS18735 07059f7816ea2c2c1997acc7710bf5ea 532 SUPERFAMILY SSF53383 139 341 1.51E-43 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS18735 07059f7816ea2c2c1997acc7710bf5ea 532 SUPERFAMILY SSF53383 378 514 1.51E-43 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS18735 07059f7816ea2c2c1997acc7710bf5ea 532 Pfam PF00155 Aminotransferase class I and II 180 512 2.3E-24 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS18735 07059f7816ea2c2c1997acc7710bf5ea 532 Gene3D G3DSA:3.90.1150.10 387 524 6.5E-13 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS18735 07059f7816ea2c2c1997acc7710bf5ea 532 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 315 328 - T 05-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 K08M4_RS18735 07059f7816ea2c2c1997acc7710bf5ea 532 Gene3D G3DSA:3.40.640.10 135 352 5.4E-37 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS19770 c171c5dab5e0a266af6c1425800bab5b 261 PIRSF PIRSF000513 4 261 1.1E-95 T 05-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS19770 c171c5dab5e0a266af6c1425800bab5b 261 Pfam PF02110 Hydroxyethylthiazole kinase family 10 252 1.8E-71 T 05-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS19770 c171c5dab5e0a266af6c1425800bab5b 261 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 12 255 29.758 T 05-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS19770 c171c5dab5e0a266af6c1425800bab5b 261 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 88 105 1.9E-33 T 05-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS19770 c171c5dab5e0a266af6c1425800bab5b 261 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 119 133 1.9E-33 T 05-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS19770 c171c5dab5e0a266af6c1425800bab5b 261 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 163 180 1.9E-33 T 05-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS19770 c171c5dab5e0a266af6c1425800bab5b 261 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 18 25 1.9E-33 T 05-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS19770 c171c5dab5e0a266af6c1425800bab5b 261 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 31 52 1.9E-33 T 05-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS19770 c171c5dab5e0a266af6c1425800bab5b 261 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 62 70 1.9E-33 T 05-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS19770 c171c5dab5e0a266af6c1425800bab5b 261 Gene3D G3DSA:3.40.1190.20 3 260 3.2E-82 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS19770 c171c5dab5e0a266af6c1425800bab5b 261 SUPERFAMILY SSF53613 6 260 1.23E-60 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS06450 d8673df1cc9d17f366a7c663eb6519d6 460 Gene3D G3DSA:3.40.640.10 127 349 1.1E-55 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS06450 d8673df1cc9d17f366a7c663eb6519d6 460 SUPERFAMILY SSF53383 117 440 2.09E-75 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS06450 d8673df1cc9d17f366a7c663eb6519d6 460 Gene3D G3DSA:1.10.10.10 1 67 3.7E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06450 d8673df1cc9d17f366a7c663eb6519d6 460 SMART SM00345 7 66 3.2E-6 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS06450 d8673df1cc9d17f366a7c663eb6519d6 460 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.4E-8 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS06450 d8673df1cc9d17f366a7c663eb6519d6 460 Pfam PF00155 Aminotransferase class I and II 110 438 5.6E-32 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS06450 d8673df1cc9d17f366a7c663eb6519d6 460 SUPERFAMILY SSF46785 1 75 1.75E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 PIRSF PIRSF001438 1 312 1.4E-121 T 05-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 7 298 8.6E-114 T 05-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 7 213 7.4E-79 T 05-07-2017 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 Gene3D G3DSA:3.30.160.40 222 306 7.4E-27 T 05-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 Gene3D G3DSA:3.40.190.10 112 200 3.5E-40 T 05-07-2017 K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 SUPERFAMILY SSF54782 221 310 4.97E-27 T 05-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 232 248 - T 05-07-2017 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 228 296 1.8E-19 T 05-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 SUPERFAMILY SSF53850 6 220 1.74E-85 T 05-07-2017 K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 6 298 39.835 T 05-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 Gene3D G3DSA:3.40.190.10 5 111 6.8E-49 T 05-07-2017 K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 PRINTS PR00151 Porphobilinogen deaminase signature 46 66 2.1E-47 T 05-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 PRINTS PR00151 Porphobilinogen deaminase signature 144 161 2.1E-47 T 05-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 PRINTS PR00151 Porphobilinogen deaminase signature 77 96 2.1E-47 T 05-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 PRINTS PR00151 Porphobilinogen deaminase signature 125 142 2.1E-47 T 05-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS00400 ee1b792fd5763180697bb256f281e007 312 PRINTS PR00151 Porphobilinogen deaminase signature 231 248 2.1E-47 T 05-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 K08M4_RS15880 7c365cd832eac84238ba6bb1d7261d22 726 Pfam PF02446 4-alpha-glucanotransferase 177 699 3.2E-125 T 05-07-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 K08M4_RS15880 7c365cd832eac84238ba6bb1d7261d22 726 SUPERFAMILY SSF51445 633 718 1.44E-147 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS15880 7c365cd832eac84238ba6bb1d7261d22 726 SUPERFAMILY SSF51445 162 594 1.44E-147 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS15880 7c365cd832eac84238ba6bb1d7261d22 726 Gene3D G3DSA:3.20.20.80 169 607 9.3E-158 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS15880 7c365cd832eac84238ba6bb1d7261d22 726 Gene3D G3DSA:3.20.20.80 646 712 9.3E-158 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS15880 7c365cd832eac84238ba6bb1d7261d22 726 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 127 716 4.4E-185 T 05-07-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 K08M4_RS08730 27e19ccce0f5bb655cf8610a39624b50 219 Pfam PF11140 Protein of unknown function (DUF2913) 3 214 3.0E-78 T 05-07-2017 IPR021316 Protein of unknown function DUF2913 K08M4_RS14470 d23e35b3f6986cf70979e962e8565dd5 459 SUPERFAMILY SSF52540 226 355 7.54E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14470 d23e35b3f6986cf70979e962e8565dd5 459 SUPERFAMILY SSF52540 17 157 7.54E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14470 d23e35b3f6986cf70979e962e8565dd5 459 Gene3D G3DSA:3.40.50.300 248 367 2.9E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14470 d23e35b3f6986cf70979e962e8565dd5 459 SMART SM00487 1 179 0.0022 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS14470 d23e35b3f6986cf70979e962e8565dd5 459 Gene3D G3DSA:3.40.50.300 2 160 5.5E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14470 d23e35b3f6986cf70979e962e8565dd5 459 Pfam PF00271 Helicase conserved C-terminal domain 265 352 1.0E-4 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS14470 d23e35b3f6986cf70979e962e8565dd5 459 Pfam PF04851 Type III restriction enzyme, res subunit 2 154 2.3E-11 T 05-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 K08M4_RS06480 e9f27269dcb5ebb39b7debca4cc086b9 217 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 2 215 36.163 T 05-07-2017 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 K08M4_RS06480 e9f27269dcb5ebb39b7debca4cc086b9 217 PIRSF PIRSF023956 1 217 2.7E-74 T 05-07-2017 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 K08M4_RS06480 e9f27269dcb5ebb39b7debca4cc086b9 217 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 3 214 1.3E-74 T 05-07-2017 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 K08M4_RS06480 e9f27269dcb5ebb39b7debca4cc086b9 217 Gene3D G3DSA:3.40.50.150 17 214 1.6E-57 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS06480 e9f27269dcb5ebb39b7debca4cc086b9 217 TIGRFAM TIGR03840 TMPT_Se_Te: thiopurine S-methyltransferase, Se/Te detoxification family 5 214 9.0E-81 T 05-07-2017 IPR022474 Thiopurine S-methyltransferase, Se/Te detoxification GO:0008119|GO:0010038|GO:0032259 KEGG: 00983+2.1.1.67 K08M4_RS06480 e9f27269dcb5ebb39b7debca4cc086b9 217 SUPERFAMILY SSF53335 2 214 2.05E-55 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS02265 f77eb1cd423298292b2cb75bb3f8baec 90 SUPERFAMILY SSF53254 7 90 2.36E-23 T 05-07-2017 IPR029033 Histidine phosphatase superfamily K08M4_RS02265 f77eb1cd423298292b2cb75bb3f8baec 90 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 89 3.5E-21 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 K08M4_RS02265 f77eb1cd423298292b2cb75bb3f8baec 90 SMART SM00855 7 76 7.7E-5 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 K08M4_RS02265 f77eb1cd423298292b2cb75bb3f8baec 90 Gene3D G3DSA:3.40.50.1240 5 89 7.5E-25 T 05-07-2017 IPR029033 Histidine phosphatase superfamily K08M4_RS13140 9302bc89945f3b9ac059034956766fa6 176 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS13140 9302bc89945f3b9ac059034956766fa6 176 SUPERFAMILY SSF54523 7 83 1.18E-13 T 05-07-2017 K08M4_RS13140 9302bc89945f3b9ac059034956766fa6 176 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 26 2.3E-8 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS13140 9302bc89945f3b9ac059034956766fa6 176 Gene3D G3DSA:3.30.700.10 7 42 5.5E-6 T 05-07-2017 K08M4_RS13140 9302bc89945f3b9ac059034956766fa6 176 Pfam PF13633 Prokaryotic N-terminal methylation site 4 28 3.4E-9 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS06270 2d4bc3ced7f2e725eb393ce1d65bacf1 294 SUPERFAMILY SSF46785 5 84 6.44E-9 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06270 2d4bc3ced7f2e725eb393ce1d65bacf1 294 Pfam PF03466 LysR substrate binding domain 93 289 1.9E-11 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS06270 2d4bc3ced7f2e725eb393ce1d65bacf1 294 Gene3D G3DSA:3.40.190.10 87 197 1.0E-9 T 05-07-2017 K08M4_RS06270 2d4bc3ced7f2e725eb393ce1d65bacf1 294 SUPERFAMILY SSF53850 87 287 1.05E-18 T 05-07-2017 K08M4_RS06270 2d4bc3ced7f2e725eb393ce1d65bacf1 294 Gene3D G3DSA:1.10.10.10 4 85 1.2E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS02795 902fdfeccd913d410c5eceb1d52b96cb 561 Gene3D G3DSA:3.30.450.90 163 288 3.2E-50 T 05-07-2017 K08M4_RS02795 902fdfeccd913d410c5eceb1d52b96cb 561 SUPERFAMILY SSF52540 171 558 4.04E-94 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02795 902fdfeccd913d410c5eceb1d52b96cb 561 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 383 397 - T 05-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 K08M4_RS02795 902fdfeccd913d410c5eceb1d52b96cb 561 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 43 141 1.2E-16 T 05-07-2017 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 K08M4_RS02795 902fdfeccd913d410c5eceb1d52b96cb 561 Gene3D G3DSA:3.40.50.300 294 559 1.8E-97 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02795 902fdfeccd913d410c5eceb1d52b96cb 561 SUPERFAMILY SSF160246 2 140 7.32E-30 T 05-07-2017 K08M4_RS02795 902fdfeccd913d410c5eceb1d52b96cb 561 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 5 559 6.2E-234 T 05-07-2017 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 K08M4_RS02795 902fdfeccd913d410c5eceb1d52b96cb 561 Pfam PF00437 Type II/IV secretion system protein 188 455 4.5E-84 T 05-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 K08M4_RS12350 2ed42d019a1300325674f0b4c17d5091 173 SUPERFAMILY SSF52218 1 166 3.02E-47 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS12350 2ed42d019a1300325674f0b4c17d5091 173 Gene3D G3DSA:3.40.50.360 1 166 5.9E-57 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS12350 2ed42d019a1300325674f0b4c17d5091 173 PIRSF PIRSF038996 1 172 1.9E-56 T 05-07-2017 IPR010086 Flavodoxin, long chain GO:0010181 K08M4_RS12350 2ed42d019a1300325674f0b4c17d5091 173 Pfam PF00258 Flavodoxin 5 161 8.9E-27 T 05-07-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 K08M4_RS12350 2ed42d019a1300325674f0b4c17d5091 173 TIGRFAM TIGR01752 flav_long: flavodoxin 2 167 4.6E-65 T 05-07-2017 IPR010086 Flavodoxin, long chain GO:0010181 K08M4_RS12350 2ed42d019a1300325674f0b4c17d5091 173 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 05-07-2017 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 K08M4_RS03850 eaff1320a7cd409cd1b3a21788bf8e0a 193 SUPERFAMILY SSF160443 93 175 1.7E-14 T 05-07-2017 IPR002625 Smr domain K08M4_RS03850 eaff1320a7cd409cd1b3a21788bf8e0a 193 Pfam PF01713 Smr domain 95 175 3.9E-21 T 05-07-2017 IPR002625 Smr domain K08M4_RS03850 eaff1320a7cd409cd1b3a21788bf8e0a 193 SMART SM00463 92 175 1.1E-12 T 05-07-2017 IPR002625 Smr domain K08M4_RS02315 af26ac63a4cf845af67f9a3e9620ffaf 507 SUPERFAMILY SSF55604 421 494 1.7E-17 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS02315 af26ac63a4cf845af67f9a3e9620ffaf 507 Gene3D G3DSA:3.30.1360.60 418 495 8.2E-23 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS02315 af26ac63a4cf845af67f9a3e9620ffaf 507 Pfam PF02378 Phosphotransferase system, EIIC 16 334 2.6E-77 T 05-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 K08M4_RS02315 af26ac63a4cf845af67f9a3e9620ffaf 507 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 397 481 2.8E-16 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS02315 af26ac63a4cf845af67f9a3e9620ffaf 507 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 434 451 - T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS02315 af26ac63a4cf845af67f9a3e9620ffaf 507 Pfam PF00367 phosphotransferase system, EIIB 424 456 3.4E-11 T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS11940 e9fa827a1788a6a8c5816650f1af874f 350 SUPERFAMILY SSF111337 1 345 1.44E-137 T 05-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 K08M4_RS11940 e9fa827a1788a6a8c5816650f1af874f 350 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 346 1.6E-156 T 05-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 K08M4_RS11940 e9fa827a1788a6a8c5816650f1af874f 350 Gene3D G3DSA:3.40.1780.10 179 345 1.2E-100 T 05-07-2017 K08M4_RS11940 e9fa827a1788a6a8c5816650f1af874f 350 Gene3D G3DSA:3.40.1780.10 1 62 1.2E-100 T 05-07-2017 K08M4_RS11940 e9fa827a1788a6a8c5816650f1af874f 350 Pfam PF02547 Queuosine biosynthesis protein 3 345 1.8E-133 T 05-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 K08M4_RS11940 e9fa827a1788a6a8c5816650f1af874f 350 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 346 46.999 T 05-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 K08M4_RS11940 e9fa827a1788a6a8c5816650f1af874f 350 Gene3D G3DSA:2.40.10.240 64 142 2.2E-17 T 05-07-2017 K08M4_RS04695 f332e79b0d85782644097cab336cc21b 338 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 4 337 1.4E-116 T 05-07-2017 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 K08M4_RS04695 f332e79b0d85782644097cab336cc21b 338 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 85 95 - T 05-07-2017 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 K08M4_RS04695 f332e79b0d85782644097cab336cc21b 338 Gene3D G3DSA:3.40.50.40 213 337 3.3E-48 T 05-07-2017 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 K08M4_RS04695 f332e79b0d85782644097cab336cc21b 338 PIRSF PIRSF500176 2 334 1.3E-106 T 05-07-2017 K08M4_RS04695 f332e79b0d85782644097cab336cc21b 338 Pfam PF00710 Asparaginase, N-terminal 5 193 1.9E-65 T 05-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 K08M4_RS04695 f332e79b0d85782644097cab336cc21b 338 SMART SM00870 5 325 1.7E-135 T 05-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 K08M4_RS04695 f332e79b0d85782644097cab336cc21b 338 PIRSF PIRSF001220 1 336 2.1E-93 T 05-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 K08M4_RS04695 f332e79b0d85782644097cab336cc21b 338 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 8 16 - T 05-07-2017 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 K08M4_RS04695 f332e79b0d85782644097cab336cc21b 338 Gene3D G3DSA:3.40.50.1170 4 207 6.9E-78 T 05-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 K08M4_RS04695 f332e79b0d85782644097cab336cc21b 338 SUPERFAMILY SSF53774 3 337 3.01E-110 T 05-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 K08M4_RS04695 f332e79b0d85782644097cab336cc21b 338 PRINTS PR00139 Asparaginase/glutaminase family signature 84 102 8.5E-17 T 05-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 K08M4_RS04695 f332e79b0d85782644097cab336cc21b 338 PRINTS PR00139 Asparaginase/glutaminase family signature 6 17 8.5E-17 T 05-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 K08M4_RS04695 f332e79b0d85782644097cab336cc21b 338 PRINTS PR00139 Asparaginase/glutaminase family signature 262 280 8.5E-17 T 05-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 K08M4_RS17370 776a389dc3b09982132019528235a178 361 Pfam PF07995 Glucose / Sorbosone dehydrogenase 37 358 7.7E-113 T 05-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 K08M4_RS17370 776a389dc3b09982132019528235a178 361 SUPERFAMILY SSF50952 25 358 2.48E-40 T 05-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 K08M4_RS17370 776a389dc3b09982132019528235a178 361 Gene3D G3DSA:2.120.10.30 12 360 4.2E-90 T 05-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like K08M4_RS15760 ddc8502836a3f7ce67272abe675076d7 956 SUPERFAMILY SSF48208 383 868 6.8E-62 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 K08M4_RS15760 ddc8502836a3f7ce67272abe675076d7 956 Pfam PF06202 Amylo-alpha-1,6-glucosidase 413 793 2.0E-98 T 05-07-2017 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25+3.2.1.33|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 K08M4_RS15760 ddc8502836a3f7ce67272abe675076d7 956 Gene3D G3DSA:1.50.10.10 436 537 3.7E-4 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 K08M4_RS15760 ddc8502836a3f7ce67272abe675076d7 956 Gene3D G3DSA:1.50.10.10 571 700 3.7E-4 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 K08M4_RS16230 77f4a09fa9b5b627f96bfebd3e07d821 317 SUPERFAMILY SSF46785 2 85 2.24E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16230 77f4a09fa9b5b627f96bfebd3e07d821 317 Gene3D G3DSA:3.40.190.10 172 278 2.3E-18 T 05-07-2017 K08M4_RS16230 77f4a09fa9b5b627f96bfebd3e07d821 317 SUPERFAMILY SSF53850 90 307 1.09E-32 T 05-07-2017 K08M4_RS16230 77f4a09fa9b5b627f96bfebd3e07d821 317 Gene3D G3DSA:1.10.10.10 1 86 1.6E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16230 77f4a09fa9b5b627f96bfebd3e07d821 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 5.9E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS16230 77f4a09fa9b5b627f96bfebd3e07d821 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 5.9E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS16230 77f4a09fa9b5b627f96bfebd3e07d821 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 5.9E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS16230 77f4a09fa9b5b627f96bfebd3e07d821 317 Gene3D G3DSA:3.40.190.10 90 171 7.9E-28 T 05-07-2017 K08M4_RS16230 77f4a09fa9b5b627f96bfebd3e07d821 317 Gene3D G3DSA:3.40.190.10 283 311 7.9E-28 T 05-07-2017 K08M4_RS16230 77f4a09fa9b5b627f96bfebd3e07d821 317 Pfam PF03466 LysR substrate binding domain 95 307 4.2E-11 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS16230 77f4a09fa9b5b627f96bfebd3e07d821 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.7E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS15625 81faa3ad619f1f2695553bcf34ad662a 326 Pfam PF06224 Winged helix DNA-binding domain 1 296 9.1E-64 T 05-07-2017 IPR009351 Protein of unknown function DUF1006 K08M4_RS03295 c0f101063fcbc21fe557ef2fb4a12307 212 SUPERFAMILY SSF46894 150 208 1.39E-16 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS03295 c0f101063fcbc21fe557ef2fb4a12307 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 205 3.8E-15 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS03295 c0f101063fcbc21fe557ef2fb4a12307 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.5E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS03295 c0f101063fcbc21fe557ef2fb4a12307 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.5E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS03295 c0f101063fcbc21fe557ef2fb4a12307 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.5E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS03295 c0f101063fcbc21fe557ef2fb4a12307 212 Gene3D G3DSA:1.10.10.10 110 206 1.3E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS03295 c0f101063fcbc21fe557ef2fb4a12307 212 SMART SM00421 151 208 5.7E-17 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS14750 70899c14aeab2a723697d858c8741e98 305 Gene3D G3DSA:3.40.1500.10 5 305 2.7E-136 T 05-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS14750 70899c14aeab2a723697d858c8741e98 305 PIRSF PIRSF000166 2 305 3.5E-127 T 05-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS14750 70899c14aeab2a723697d858c8741e98 305 Pfam PF01218 Coproporphyrinogen III oxidase 9 305 1.4E-130 T 05-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS14750 70899c14aeab2a723697d858c8741e98 305 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 170 194 - T 05-07-2017 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS14750 70899c14aeab2a723697d858c8741e98 305 PRINTS PR00073 Coprogen oxidase signature 238 265 8.7E-70 T 05-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS14750 70899c14aeab2a723697d858c8741e98 305 PRINTS PR00073 Coprogen oxidase signature 266 292 8.7E-70 T 05-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS14750 70899c14aeab2a723697d858c8741e98 305 PRINTS PR00073 Coprogen oxidase signature 129 151 8.7E-70 T 05-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS14750 70899c14aeab2a723697d858c8741e98 305 PRINTS PR00073 Coprogen oxidase signature 166 195 8.7E-70 T 05-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS14750 70899c14aeab2a723697d858c8741e98 305 PRINTS PR00073 Coprogen oxidase signature 31 47 8.7E-70 T 05-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS14750 70899c14aeab2a723697d858c8741e98 305 PRINTS PR00073 Coprogen oxidase signature 94 118 8.7E-70 T 05-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS14750 70899c14aeab2a723697d858c8741e98 305 SUPERFAMILY SSF102886 5 305 4.84E-137 T 05-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS14750 70899c14aeab2a723697d858c8741e98 305 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 3 281 56.471 T 05-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS04610 e890bebab1ca774674b491603991ead0 756 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 355 6.9E-134 T 05-07-2017 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 K08M4_RS04610 e890bebab1ca774674b491603991ead0 756 Pfam PF13177 DNA polymerase III, delta subunit 20 178 7.7E-44 T 05-07-2017 K08M4_RS04610 e890bebab1ca774674b491603991ead0 756 Pfam PF12168 DNA polymerase III subunits tau domain IV DnaB-binding 539 613 2.6E-20 T 05-07-2017 IPR022001 DNA polymerase III subunit tau, DnaB-binding domain IV KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS04610 e890bebab1ca774674b491603991ead0 756 SUPERFAMILY SSF48019 243 361 1.02E-33 T 05-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 K08M4_RS04610 e890bebab1ca774674b491603991ead0 756 Gene3D G3DSA:1.10.8.60 167 242 5.2E-32 T 05-07-2017 K08M4_RS04610 e890bebab1ca774674b491603991ead0 756 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 233 362 3.7E-34 T 05-07-2017 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 K08M4_RS04610 e890bebab1ca774674b491603991ead0 756 Gene3D G3DSA:1.20.272.10 243 360 3.2E-45 T 05-07-2017 K08M4_RS04610 e890bebab1ca774674b491603991ead0 756 SMART SM00382 37 179 1.3E-5 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS04610 e890bebab1ca774674b491603991ead0 756 Gene3D G3DSA:3.40.50.300 15 166 2.4E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04610 e890bebab1ca774674b491603991ead0 756 SUPERFAMILY SSF52540 33 223 7.83E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04610 e890bebab1ca774674b491603991ead0 756 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 615 753 2.7E-48 T 05-07-2017 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS10470 71ecdf01b4c297928b368c6a2366af84 283 PRINTS PR00412 Epoxide hydrolase signature 257 279 4.2E-6 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 K08M4_RS10470 71ecdf01b4c297928b368c6a2366af84 283 PRINTS PR00412 Epoxide hydrolase signature 54 69 4.2E-6 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 K08M4_RS10470 71ecdf01b4c297928b368c6a2366af84 283 PRINTS PR00412 Epoxide hydrolase signature 113 126 4.2E-6 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 K08M4_RS10470 71ecdf01b4c297928b368c6a2366af84 283 PRINTS PR00412 Epoxide hydrolase signature 99 112 4.2E-6 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 K08M4_RS10470 71ecdf01b4c297928b368c6a2366af84 283 PRINTS PR00412 Epoxide hydrolase signature 32 50 4.2E-6 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 K08M4_RS10470 71ecdf01b4c297928b368c6a2366af84 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 7.6E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS10470 71ecdf01b4c297928b368c6a2366af84 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 7.6E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS10470 71ecdf01b4c297928b368c6a2366af84 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 7.6E-5 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS10470 71ecdf01b4c297928b368c6a2366af84 283 Pfam PF12697 Alpha/beta hydrolase family 28 274 5.9E-19 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS10470 71ecdf01b4c297928b368c6a2366af84 283 SUPERFAMILY SSF53474 17 282 1.45E-47 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS10470 71ecdf01b4c297928b368c6a2366af84 283 Gene3D G3DSA:3.40.50.1820 13 280 1.0E-42 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS11555 2dcfa1885e38887902feef4265619153 370 Pfam PF06725 3D domain 275 351 4.2E-20 T 05-07-2017 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 K08M4_RS11555 2dcfa1885e38887902feef4265619153 370 SMART SM00925 122 255 1.0E-64 T 05-07-2017 IPR005300 Lytic transglycosylase MltA GO:0004553 K08M4_RS11555 2dcfa1885e38887902feef4265619153 370 Pfam PF03562 MltA specific insert domain 106 254 1.7E-37 T 05-07-2017 IPR005300 Lytic transglycosylase MltA GO:0004553 K08M4_RS11555 2dcfa1885e38887902feef4265619153 370 SUPERFAMILY SSF50685 27 352 1.26E-98 T 05-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain K08M4_RS11555 2dcfa1885e38887902feef4265619153 370 Gene3D G3DSA:2.40.40.10 168 358 9.3E-42 T 05-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain K08M4_RS11555 2dcfa1885e38887902feef4265619153 370 Gene3D G3DSA:2.40.40.10 90 167 2.6E-8 T 05-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain K08M4_RS21070 2b07e27737af9f18b984f7a024311953 215 Pfam PF13417 Glutathione S-transferase, N-terminal domain 9 77 7.1E-9 T 05-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 K08M4_RS21070 2b07e27737af9f18b984f7a024311953 215 Pfam PF14834 Glutathione S-transferase, C-terminal domain 87 197 1.8E-7 T 05-07-2017 K08M4_RS21070 2b07e27737af9f18b984f7a024311953 215 SUPERFAMILY SSF47616 83 199 1.24E-15 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS21070 2b07e27737af9f18b984f7a024311953 215 Gene3D G3DSA:1.20.1050.10 91 203 4.9E-46 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS21070 2b07e27737af9f18b984f7a024311953 215 SUPERFAMILY SSF52833 4 84 2.12E-15 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS21070 2b07e27737af9f18b984f7a024311953 215 Gene3D G3DSA:3.40.30.10 9 90 4.9E-14 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS09240 1cc1327065293da323959703e3d5c571 208 Gene3D G3DSA:3.40.50.880 3 190 2.6E-52 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS09240 1cc1327065293da323959703e3d5c571 208 PRINTS PR00096 Glutamine amidotransferase superfamily signature 52 61 1.1E-12 T 05-07-2017 K08M4_RS09240 1cc1327065293da323959703e3d5c571 208 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 1.1E-12 T 05-07-2017 K08M4_RS09240 1cc1327065293da323959703e3d5c571 208 PRINTS PR00096 Glutamine amidotransferase superfamily signature 79 90 1.1E-12 T 05-07-2017 K08M4_RS09240 1cc1327065293da323959703e3d5c571 208 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 79 95 7.1E-5 T 05-07-2017 K08M4_RS09240 1cc1327065293da323959703e3d5c571 208 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 49 63 7.1E-5 T 05-07-2017 K08M4_RS09240 1cc1327065293da323959703e3d5c571 208 Pfam PF00117 Glutamine amidotransferase class-I 6 186 2.4E-43 T 05-07-2017 IPR017926 Glutamine amidotransferase K08M4_RS09240 1cc1327065293da323959703e3d5c571 208 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 188 1.3E-51 T 05-07-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 K08M4_RS09240 1cc1327065293da323959703e3d5c571 208 PRINTS PR00097 Anthranilate synthase component II signature 104 112 8.9E-34 T 05-07-2017 K08M4_RS09240 1cc1327065293da323959703e3d5c571 208 PRINTS PR00097 Anthranilate synthase component II signature 79 90 8.9E-34 T 05-07-2017 K08M4_RS09240 1cc1327065293da323959703e3d5c571 208 PRINTS PR00097 Anthranilate synthase component II signature 166 179 8.9E-34 T 05-07-2017 K08M4_RS09240 1cc1327065293da323959703e3d5c571 208 PRINTS PR00097 Anthranilate synthase component II signature 4 18 8.9E-34 T 05-07-2017 K08M4_RS09240 1cc1327065293da323959703e3d5c571 208 PRINTS PR00097 Anthranilate synthase component II signature 124 136 8.9E-34 T 05-07-2017 K08M4_RS09240 1cc1327065293da323959703e3d5c571 208 PRINTS PR00097 Anthranilate synthase component II signature 52 61 8.9E-34 T 05-07-2017 K08M4_RS09240 1cc1327065293da323959703e3d5c571 208 SUPERFAMILY SSF52317 3 192 2.37E-46 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS17890 e951927659a298c70f7c71951fcfa67b 227 SUPERFAMILY SSF46894 148 215 5.1E-19 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS17890 e951927659a298c70f7c71951fcfa67b 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 213 2.2E-20 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS17890 e951927659a298c70f7c71951fcfa67b 227 SMART SM00421 156 213 7.3E-22 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS17890 e951927659a298c70f7c71951fcfa67b 227 Gene3D G3DSA:1.10.10.10 157 213 1.1E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS17890 e951927659a298c70f7c71951fcfa67b 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 1.3E-12 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS17890 e951927659a298c70f7c71951fcfa67b 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 1.3E-12 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS17890 e951927659a298c70f7c71951fcfa67b 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 1.3E-12 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS17890 e951927659a298c70f7c71951fcfa67b 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS13135 c1343a0e377d6c8833ad1f45d10e0520 183 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 14 35 8.4E-8 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS13135 c1343a0e377d6c8833ad1f45d10e0520 183 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 15 38 1.7E-8 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS13135 c1343a0e377d6c8833ad1f45d10e0520 183 SUPERFAMILY SSF54523 18 71 2.98E-8 T 05-07-2017 K08M4_RS17645 117c733fb92544e06b8a5aefb3573373 487 Pfam PF00990 Diguanylate cyclase, GGDEF domain 320 473 4.9E-35 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS17645 117c733fb92544e06b8a5aefb3573373 487 Pfam PF08269 Cache domain 30 280 1.1E-19 T 05-07-2017 IPR004010 Double Cache domain 2 K08M4_RS17645 117c733fb92544e06b8a5aefb3573373 487 Gene3D G3DSA:3.30.70.270 323 480 1.8E-39 T 05-07-2017 K08M4_RS17645 117c733fb92544e06b8a5aefb3573373 487 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 320 476 4.0E-35 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS17645 117c733fb92544e06b8a5aefb3573373 487 SMART SM00267 310 477 2.8E-39 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS17645 117c733fb92544e06b8a5aefb3573373 487 Gene3D G3DSA:3.30.450.20 184 280 4.7E-10 T 05-07-2017 K08M4_RS17645 117c733fb92544e06b8a5aefb3573373 487 Gene3D G3DSA:3.30.450.20 21 175 4.4E-9 T 05-07-2017 K08M4_RS17645 117c733fb92544e06b8a5aefb3573373 487 SUPERFAMILY SSF55073 325 479 8.63E-38 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS02115 9095d41b3e810dfdc5f712165dcc9d2b 239 Pfam PF02390 Putative methyltransferase 62 232 1.7E-57 T 05-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 K08M4_RS02115 9095d41b3e810dfdc5f712165dcc9d2b 239 SUPERFAMILY SSF53335 16 237 1.27E-34 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS02115 9095d41b3e810dfdc5f712165dcc9d2b 239 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 23 238 29.683 T 05-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 K08M4_RS02115 9095d41b3e810dfdc5f712165dcc9d2b 239 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 48 238 9.0E-67 T 05-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 K08M4_RS02115 9095d41b3e810dfdc5f712165dcc9d2b 239 Gene3D G3DSA:3.40.50.150 60 193 2.1E-12 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS17555 6fb99dbfcdd2755a54fa369233c3ad10 112 Pfam PF08274 PhnA Zinc-Ribbon 2 30 1.1E-13 T 05-07-2017 IPR013987 PhnA protein, N-terminal K08M4_RS17555 6fb99dbfcdd2755a54fa369233c3ad10 112 SUPERFAMILY SSF82057 39 111 7.78E-22 T 05-07-2017 K08M4_RS17555 6fb99dbfcdd2755a54fa369233c3ad10 112 SUPERFAMILY SSF57783 1 35 1.36E-13 T 05-07-2017 K08M4_RS17555 6fb99dbfcdd2755a54fa369233c3ad10 112 Gene3D G3DSA:2.20.25.10 1 39 1.1E-19 T 05-07-2017 K08M4_RS17555 6fb99dbfcdd2755a54fa369233c3ad10 112 Pfam PF03831 PhnA domain 44 112 4.9E-24 T 05-07-2017 IPR013988 PhnA protein, C-terminal K08M4_RS17555 6fb99dbfcdd2755a54fa369233c3ad10 112 Gene3D G3DSA:2.30.30.40 43 111 7.9E-25 T 05-07-2017 K08M4_RS17555 6fb99dbfcdd2755a54fa369233c3ad10 112 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 2 111 2.2E-38 T 05-07-2017 IPR004624 PhnA protein K08M4_RS05005 c5271aeacdbd8ed1e615f0ed158183c1 488 SUPERFAMILY SSF55073 338 487 8.63E-36 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS05005 c5271aeacdbd8ed1e615f0ed158183c1 488 Pfam PF00990 Diguanylate cyclase, GGDEF domain 333 485 7.6E-34 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS05005 c5271aeacdbd8ed1e615f0ed158183c1 488 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 331 487 3.2E-40 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS05005 c5271aeacdbd8ed1e615f0ed158183c1 488 Gene3D G3DSA:3.30.70.270 336 488 7.6E-39 T 05-07-2017 K08M4_RS05005 c5271aeacdbd8ed1e615f0ed158183c1 488 SMART SM00267 322 488 1.2E-32 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS05005 c5271aeacdbd8ed1e615f0ed158183c1 488 SUPERFAMILY SSF103190 140 241 7.06E-5 T 05-07-2017 IPR029151 Periplasmic sensor domain-like K08M4_RS09365 df68569480b1ab4cc086fb9adbc522a3 260 SUPERFAMILY SSF52540 3 252 2.18E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09365 df68569480b1ab4cc086fb9adbc522a3 260 SMART SM00382 38 227 2.8E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS09365 df68569480b1ab4cc086fb9adbc522a3 260 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS09365 df68569480b1ab4cc086fb9adbc522a3 260 Pfam PF00005 ABC transporter 30 178 2.2E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS09365 df68569480b1ab4cc086fb9adbc522a3 260 Gene3D G3DSA:3.40.50.300 2 252 2.9E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16890 3d7992badd3dc261039d30d5bc2b50d8 367 PIRSF PIRSF000524 1 364 5.5E-59 T 05-07-2017 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 K08M4_RS16890 3d7992badd3dc261039d30d5bc2b50d8 367 Pfam PF00266 Aminotransferase class-V 37 316 2.5E-28 T 05-07-2017 IPR000192 Aminotransferase class V domain K08M4_RS16890 3d7992badd3dc261039d30d5bc2b50d8 367 TIGRFAM TIGR02326 transamin_PhnW: 2-aminoethylphosphonate--pyruvate transaminase 3 364 7.2E-194 T 05-07-2017 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 K08M4_RS16890 3d7992badd3dc261039d30d5bc2b50d8 367 SUPERFAMILY SSF53383 3 362 1.88E-84 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS16890 3d7992badd3dc261039d30d5bc2b50d8 367 Hamap MF_01376 2-aminoethylphosphonate--pyruvate transaminase [phnW]. 1 367 209.67 T 05-07-2017 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 K08M4_RS16890 3d7992badd3dc261039d30d5bc2b50d8 367 Gene3D G3DSA:3.90.1150.10 255 360 7.9E-47 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS16890 3d7992badd3dc261039d30d5bc2b50d8 367 Gene3D G3DSA:3.40.640.10 17 254 2.4E-53 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS16890 3d7992badd3dc261039d30d5bc2b50d8 367 TIGRFAM TIGR03301 PhnW-AepZ: 2-aminoethylphosphonate aminotransferase 6 362 4.4E-165 T 05-07-2017 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 K08M4_RS04845 a0a9af0ae131da4cac5dd770b0e8ee53 144 ProDom PD087558 YRN2_VIBPA ORF2 VV1184 VV13101 MOTY 3'REGION VC1009 VP2110 1 143 1.0E-63 T 05-07-2017 IPR020206 Uncharacterised protein family, VP2110 K08M4_RS04845 a0a9af0ae131da4cac5dd770b0e8ee53 144 Pfam PF10952 Protein of unknown function (DUF2753) 5 144 2.3E-74 T 05-07-2017 IPR020206 Uncharacterised protein family, VP2110 K08M4_RS12235 10805be2ffa58b9ed99f9fecafaf2df1 166 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 56 64 2.0E-17 T 05-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 K08M4_RS12235 10805be2ffa58b9ed99f9fecafaf2df1 166 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 104 119 2.0E-17 T 05-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 K08M4_RS12235 10805be2ffa58b9ed99f9fecafaf2df1 166 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 140 156 2.0E-17 T 05-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 K08M4_RS12235 10805be2ffa58b9ed99f9fecafaf2df1 166 TIGRFAM TIGR00077 lspA: signal peptidase II 8 163 4.0E-48 T 05-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 K08M4_RS12235 10805be2ffa58b9ed99f9fecafaf2df1 166 Pfam PF01252 Signal peptidase (SPase) II 17 159 3.2E-35 T 05-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 K08M4_RS12235 10805be2ffa58b9ed99f9fecafaf2df1 166 ProSitePatterns PS00855 Signal peptidases II signature. 107 119 - T 05-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 K08M4_RS12235 10805be2ffa58b9ed99f9fecafaf2df1 166 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 8 165 16.579 T 05-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 K08M4_RS09085 cdbfc8cc111bb710d0940ac9b0d70942 209 Gene3D G3DSA:1.25.40.10 124 207 1.1E-31 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS09085 cdbfc8cc111bb710d0940ac9b0d70942 209 SUPERFAMILY SSF48452 72 190 6.72E-16 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS09085 cdbfc8cc111bb710d0940ac9b0d70942 209 Gene3D G3DSA:1.25.40.10 72 123 7.4E-11 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS09085 cdbfc8cc111bb710d0940ac9b0d70942 209 SMART SM00028 158 191 230.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS09085 cdbfc8cc111bb710d0940ac9b0d70942 209 SMART SM00028 86 119 3.2E-4 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS09085 cdbfc8cc111bb710d0940ac9b0d70942 209 Pfam PF13414 TPR repeat 95 125 2.3E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS15945 1bf459afcd8880ce72a8ad57d914f78c 88 Pfam PF04728 Lipoprotein leucine-zipper 29 88 6.6E-19 T 05-07-2017 IPR006817 Lipoprotein leucine-zipper GO:0019867 K08M4_RS15945 1bf459afcd8880ce72a8ad57d914f78c 88 PIRSF PIRSF002855 1 88 1.8E-24 T 05-07-2017 IPR016367 Murein-lipoprotein K08M4_RS15945 1bf459afcd8880ce72a8ad57d914f78c 88 SUPERFAMILY SSF58042 18 87 3.92E-13 T 05-07-2017 K08M4_RS20245 ea18b43b57c063621978aeba1f6e1409 228 Gene3D G3DSA:3.10.129.10 77 212 6.4E-26 T 05-07-2017 IPR029069 HotDog domain K08M4_RS20245 ea18b43b57c063621978aeba1f6e1409 228 SUPERFAMILY SSF54637 78 222 1.91E-26 T 05-07-2017 IPR029069 HotDog domain K08M4_RS20245 ea18b43b57c063621978aeba1f6e1409 228 Pfam PF01575 MaoC like domain 84 201 4.8E-20 T 05-07-2017 IPR002539 MaoC-like domain K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 SMART SM00388 125 191 6.2E-12 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 18 86 1.0E-5 T 05-07-2017 IPR000014 PAS domain K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 SUPERFAMILY SSF55785 14 90 4.38E-9 T 05-07-2017 IPR000014 PAS domain K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 Pfam PF00512 His Kinase A (phospho-acceptor) domain 125 189 3.6E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 Gene3D G3DSA:1.10.287.130 122 187 5.6E-7 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 238 339 9.3E-21 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 SUPERFAMILY SSF55874 180 338 4.06E-35 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 SUPERFAMILY SSF47384 120 191 4.32E-10 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 Gene3D G3DSA:3.30.450.20 17 120 6.3E-10 T 05-07-2017 K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 Pfam PF13188 PAS domain 21 68 8.3E-9 T 05-07-2017 IPR000014 PAS domain K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 SMART SM00091 21 84 9.4E-7 T 05-07-2017 IPR000014 PAS domain K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 Gene3D G3DSA:3.30.565.10 195 339 6.5E-36 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 337 3.9E-18 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 300 318 3.9E-18 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 285 3.9E-18 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 PRINTS PR00344 Bacterial sensor protein C-terminal signature 289 299 3.9E-18 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS04140 05f85ed6b258577151c5c2c1edaeb4f6 346 SMART SM00387 234 340 3.5E-29 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS01970 ed001db71204006beb9e45a0999c2d07 417 Pfam PF01966 HD domain 170 290 9.7E-16 T 05-07-2017 IPR006674 HD domain K08M4_RS01970 ed001db71204006beb9e45a0999c2d07 417 SMART SM00471 164 300 3.3E-7 T 05-07-2017 IPR003607 HD/PDEase domain K08M4_RS01970 ed001db71204006beb9e45a0999c2d07 417 Gene3D G3DSA:1.10.3210.10 166 312 3.0E-18 T 05-07-2017 IPR006674 HD domain K08M4_RS01970 ed001db71204006beb9e45a0999c2d07 417 SUPERFAMILY SSF109604 164 329 4.11E-25 T 05-07-2017 K08M4_RS01970 ed001db71204006beb9e45a0999c2d07 417 Pfam PF11871 Domain of unknown function (DUF3391) 4 135 3.0E-29 T 05-07-2017 IPR021812 Protein of unknown function DUF3391 K08M4_RS14960 168f79f5d0201dfaa4e36ed9448a8961 210 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 29 207 8.5E-60 T 05-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 K08M4_RS14960 168f79f5d0201dfaa4e36ed9448a8961 210 Gene3D G3DSA:3.40.50.150 6 208 1.1E-70 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS14960 168f79f5d0201dfaa4e36ed9448a8961 210 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 16 205 28.606 T 05-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 K08M4_RS14960 168f79f5d0201dfaa4e36ed9448a8961 210 Pfam PF02527 rRNA small subunit methyltransferase G 26 204 1.8E-62 T 05-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 K08M4_RS14960 168f79f5d0201dfaa4e36ed9448a8961 210 SUPERFAMILY SSF53335 7 208 5.68E-41 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS14960 168f79f5d0201dfaa4e36ed9448a8961 210 PIRSF PIRSF003078 1 209 3.1E-61 T 05-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 K08M4_RS08465 b711005e8479f99ecd945444390704d9 505 Gene3D G3DSA:3.20.130.10 302 489 1.7E-74 T 05-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 K08M4_RS08465 b711005e8479f99ecd945444390704d9 505 PIRSF PIRSF001394 1 505 7.8E-217 T 05-07-2017 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 K08M4_RS08465 b711005e8479f99ecd945444390704d9 505 SUPERFAMILY SSF117457 316 488 4.71E-63 T 05-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 K08M4_RS08465 b711005e8479f99ecd945444390704d9 505 Pfam PF05681 Fumarate hydratase (Fumerase) 11 284 3.4E-99 T 05-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 K08M4_RS08465 b711005e8479f99ecd945444390704d9 505 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 12 283 1.3E-62 T 05-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 K08M4_RS08465 b711005e8479f99ecd945444390704d9 505 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 324 486 4.9E-51 T 05-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 K08M4_RS08465 b711005e8479f99ecd945444390704d9 505 Pfam PF05683 Fumarase C-terminus 288 489 2.4E-83 T 05-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 Pfam PF00563 EAL domain 427 661 4.2E-72 T 05-07-2017 IPR001633 EAL domain K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 Pfam PF00990 Diguanylate cyclase, GGDEF domain 253 406 2.1E-40 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 252 407 1.2E-36 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 8 118 5.0E-8 T 05-07-2017 IPR000014 PAS domain K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 Pfam PF08448 PAS fold 16 118 3.1E-7 T 05-07-2017 IPR013656 PAS fold-4 K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 SMART SM00267 236 410 4.0E-51 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 Gene3D G3DSA:3.30.70.270 255 418 2.2E-49 T 05-07-2017 K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 Gene3D G3DSA:3.20.20.450 424 673 1.3E-93 T 05-07-2017 IPR001633 EAL domain K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 SUPERFAMILY SSF141868 427 674 1.44E-84 T 05-07-2017 IPR001633 EAL domain K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 SUPERFAMILY SSF55785 5 115 1.12E-10 T 05-07-2017 IPR000014 PAS domain K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 SUPERFAMILY SSF55073 258 412 3.22E-44 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 SMART SM00052 420 666 5.9E-108 T 05-07-2017 IPR001633 EAL domain K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 Gene3D G3DSA:3.30.450.20 124 197 4.9E-7 T 05-07-2017 K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 SMART SM00091 8 74 1.2E-5 T 05-07-2017 IPR000014 PAS domain K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 SMART SM00091 131 198 4.6 T 05-07-2017 IPR000014 PAS domain K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 SUPERFAMILY SSF55785 118 189 1.1E-5 T 05-07-2017 IPR000014 PAS domain K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 Gene3D G3DSA:3.30.450.20 7 118 3.8E-11 T 05-07-2017 K08M4_RS03175 135be9b4ee5203b07ed42e0bc7c7be7c 679 Pfam PF13188 PAS domain 134 179 3.3E-5 T 05-07-2017 IPR000014 PAS domain K08M4_RS12590 9b8b07eb71f49ef717f42d33bd612ada 457 Gene3D G3DSA:3.40.1190.10 86 314 3.7E-70 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS12590 9b8b07eb71f49ef717f42d33bd612ada 457 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 33 452 1.6E-138 T 05-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS12590 9b8b07eb71f49ef717f42d33bd612ada 457 SUPERFAMILY SSF53244 318 452 1.77E-32 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS12590 9b8b07eb71f49ef717f42d33bd612ada 457 SUPERFAMILY SSF53623 104 315 3.53E-54 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS12590 9b8b07eb71f49ef717f42d33bd612ada 457 Gene3D G3DSA:3.40.1390.10 1 84 4.2E-24 T 05-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 K08M4_RS12590 9b8b07eb71f49ef717f42d33bd612ada 457 SUPERFAMILY SSF63418 1 100 2.62E-23 T 05-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 K08M4_RS12590 9b8b07eb71f49ef717f42d33bd612ada 457 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 453 32.867 T 05-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS12590 9b8b07eb71f49ef717f42d33bd612ada 457 Gene3D G3DSA:3.90.190.20 318 455 2.3E-39 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS12590 9b8b07eb71f49ef717f42d33bd612ada 457 Pfam PF01225 Mur ligase family, catalytic domain 28 79 1.7E-8 T 05-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 K08M4_RS12590 9b8b07eb71f49ef717f42d33bd612ada 457 Pfam PF08245 Mur ligase middle domain 109 297 1.7E-47 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS12590 9b8b07eb71f49ef717f42d33bd612ada 457 Pfam PF02875 Mur ligase family, glutamate ligase domain 318 398 1.8E-14 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS17215 99d692978d97bc7db57efdea9a0d5dd1 316 Hamap MF_00492 Transaldolase [tal]. 2 316 50.583 T 05-07-2017 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 K08M4_RS17215 99d692978d97bc7db57efdea9a0d5dd1 316 ProSitePatterns PS01054 Transaldolase signature 1. 31 39 - T 05-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 K08M4_RS17215 99d692978d97bc7db57efdea9a0d5dd1 316 Pfam PF00923 Transaldolase 14 312 2.7E-99 T 05-07-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 K08M4_RS17215 99d692978d97bc7db57efdea9a0d5dd1 316 Gene3D G3DSA:3.20.20.70 3 315 1.1E-127 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS17215 99d692978d97bc7db57efdea9a0d5dd1 316 TIGRFAM TIGR00874 talAB: transaldolase 3 316 1.2E-154 T 05-07-2017 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 K08M4_RS17215 99d692978d97bc7db57efdea9a0d5dd1 316 ProSitePatterns PS00958 Transaldolase active site. 129 146 - T 05-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 K08M4_RS17215 99d692978d97bc7db57efdea9a0d5dd1 316 SUPERFAMILY SSF51569 1 315 2.2E-112 T 05-07-2017 K08M4_RS18015 ff237237554be3cfb025faf685ce0b7c 147 Pfam PF05425 Copper resistance protein D 44 138 1.2E-8 T 05-07-2017 IPR008457 Copper resistance protein D GO:0016021 K08M4_RS18170 ff237237554be3cfb025faf685ce0b7c 147 Pfam PF05425 Copper resistance protein D 44 138 1.2E-8 T 05-07-2017 IPR008457 Copper resistance protein D GO:0016021 K08M4_RS16395 58bbc49a0fbe98ed53fe37a1c9c8b8b2 623 SMART SM00283 361 622 3.3E-75 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS16395 58bbc49a0fbe98ed53fe37a1c9c8b8b2 623 SUPERFAMILY SSF103190 50 184 3.1E-18 T 05-07-2017 IPR029151 Periplasmic sensor domain-like K08M4_RS16395 58bbc49a0fbe98ed53fe37a1c9c8b8b2 623 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 434 621 1.5E-46 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS16395 58bbc49a0fbe98ed53fe37a1c9c8b8b2 623 Pfam PF02743 Cache domain 33 254 2.1E-31 T 05-07-2017 IPR033479 Double Cache domain 1 K08M4_RS16395 58bbc49a0fbe98ed53fe37a1c9c8b8b2 623 SUPERFAMILY SSF58104 314 623 8.24E-76 T 05-07-2017 K08M4_RS16395 58bbc49a0fbe98ed53fe37a1c9c8b8b2 623 SMART SM00304 374 441 57.0 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS16395 58bbc49a0fbe98ed53fe37a1c9c8b8b2 623 SMART SM00304 292 346 4.0E-10 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS16395 58bbc49a0fbe98ed53fe37a1c9c8b8b2 623 Gene3D G3DSA:1.10.287.950 376 593 3.8E-56 T 05-07-2017 K08M4_RS16395 58bbc49a0fbe98ed53fe37a1c9c8b8b2 623 Gene3D G3DSA:3.30.450.20 139 270 6.1E-30 T 05-07-2017 K08M4_RS16395 58bbc49a0fbe98ed53fe37a1c9c8b8b2 623 Pfam PF00672 HAMP domain 273 342 1.3E-14 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS08750 8433f989690ab81535cd57cb0c207a93 793 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 373 509 6.5E-12 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS08750 8433f989690ab81535cd57cb0c207a93 793 SMART SM00052 527 768 4.9E-28 T 05-07-2017 IPR001633 EAL domain K08M4_RS08750 8433f989690ab81535cd57cb0c207a93 793 SMART SM00267 362 526 2.5E-7 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS08750 8433f989690ab81535cd57cb0c207a93 793 Gene3D G3DSA:3.30.70.270 375 511 5.8E-15 T 05-07-2017 K08M4_RS08750 8433f989690ab81535cd57cb0c207a93 793 SUPERFAMILY SSF141868 538 772 8.89E-47 T 05-07-2017 IPR001633 EAL domain K08M4_RS08750 8433f989690ab81535cd57cb0c207a93 793 Pfam PF00990 Diguanylate cyclase, GGDEF domain 374 511 7.3E-15 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS08750 8433f989690ab81535cd57cb0c207a93 793 SUPERFAMILY SSF55073 378 511 1.1E-17 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS08750 8433f989690ab81535cd57cb0c207a93 793 Pfam PF00563 EAL domain 541 763 7.1E-41 T 05-07-2017 IPR001633 EAL domain K08M4_RS08750 8433f989690ab81535cd57cb0c207a93 793 Gene3D G3DSA:3.20.20.450 539 774 5.6E-46 T 05-07-2017 IPR001633 EAL domain K08M4_RS01360 23e963f0298d2693397b2ef19881b1c6 70 Pfam PF06794 Uncharacterised protein family (UPF0270) 1 65 7.7E-33 T 05-07-2017 IPR010648 Uncharacterised protein family UPF0270 K08M4_RS01360 23e963f0298d2693397b2ef19881b1c6 70 ProDom PD026997 UPF0270 YHEU SO0879 3D-STRUCTURE LYASE PLU0398 YPO0179/Y3960/YP0178 ENOLASE HD0737 PSPTO1630 1 64 2.0E-22 T 05-07-2017 IPR010648 Uncharacterised protein family UPF0270 K08M4_RS01360 23e963f0298d2693397b2ef19881b1c6 70 PIRSF PIRSF006169 1 70 3.3E-34 T 05-07-2017 IPR010648 Uncharacterised protein family UPF0270 K08M4_RS01360 23e963f0298d2693397b2ef19881b1c6 70 Gene3D G3DSA:1.10.10.610 1 69 1.6E-34 T 05-07-2017 IPR010648 Uncharacterised protein family UPF0270 K08M4_RS01360 23e963f0298d2693397b2ef19881b1c6 70 SUPERFAMILY SSF118001 1 67 3.4E-27 T 05-07-2017 IPR010648 Uncharacterised protein family UPF0270 K08M4_RS01360 23e963f0298d2693397b2ef19881b1c6 70 Hamap MF_00690 UPF0270 protein YheU [yheU]. 1 70 23.715 T 05-07-2017 IPR010648 Uncharacterised protein family UPF0270 K08M4_RS09040 10a6a56fa25c21504e657aa7189b1488 198 SUPERFAMILY SSF142695 19 172 1.31E-52 T 05-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 K08M4_RS09040 10a6a56fa25c21504e657aa7189b1488 198 Pfam PF00925 GTP cyclohydrolase II 19 171 1.8E-56 T 05-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 K08M4_RS09040 10a6a56fa25c21504e657aa7189b1488 198 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 2 198 36.569 T 05-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 Gene3D G3DSA:1.10.10.60 146 198 2.7E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 SMART SM00342 108 191 9.0E-18 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 Gene3D G3DSA:3.30.310.20 203 315 2.1E-32 T 05-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 145 187 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 SUPERFAMILY SSF48150 306 479 3.61E-23 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 Gene3D G3DSA:1.10.340.30 316 440 3.9E-20 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 SUPERFAMILY SSF46689 146 193 1.25E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 SUPERFAMILY SSF57884 9 94 7.32E-33 T 05-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 Pfam PF12833 Helix-turn-helix domain 114 192 4.4E-18 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 SUPERFAMILY SSF46689 94 140 5.82E-5 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 SMART SM01009 202 315 1.7E-33 T 05-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 Gene3D G3DSA:1.10.10.60 96 140 7.1E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 Pfam PF02805 Metal binding domain of Ada 16 79 1.5E-28 T 05-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 Gene3D G3DSA:3.40.10.10 10 95 8.8E-35 T 05-07-2017 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 SUPERFAMILY SSF55945 203 296 1.21E-23 T 05-07-2017 K08M4_RS21475 9a4c7fc5fc08d8552c46839172d4f8b6 482 Pfam PF06029 AlkA N-terminal domain 203 315 2.0E-33 T 05-07-2017 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal K08M4_RS09305 d7beff506a18ac231fcf431e4e660bbe 188 SUPERFAMILY SSF48150 9 187 2.51E-74 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 K08M4_RS09305 d7beff506a18ac231fcf431e4e660bbe 188 Pfam PF03352 Methyladenine glycosylase 12 186 6.2E-74 T 05-07-2017 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 K08M4_RS09305 d7beff506a18ac231fcf431e4e660bbe 188 Gene3D G3DSA:1.10.340.30 9 186 1.2E-78 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 K08M4_RS04375 1decb5adb622850122053c58e8be3973 176 SMART SM00463 94 172 6.2E-18 T 05-07-2017 IPR002625 Smr domain K08M4_RS04375 1decb5adb622850122053c58e8be3973 176 Pfam PF01713 Smr domain 97 171 6.0E-19 T 05-07-2017 IPR002625 Smr domain K08M4_RS04375 1decb5adb622850122053c58e8be3973 176 Hamap MF_01042 UPF0115 protein YfcN [yfcN]. 1 173 38.038 T 05-07-2017 IPR022990 Uncharacterised protein family UPF0115 K08M4_RS04375 1decb5adb622850122053c58e8be3973 176 SUPERFAMILY SSF160443 95 171 3.01E-12 T 05-07-2017 IPR002625 Smr domain K08M4_RS06565 a69baf6ec36ca0243d966f767b4d90b0 205 SMART SM00855 8 157 2.0E-7 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 K08M4_RS06565 a69baf6ec36ca0243d966f767b4d90b0 205 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 192 9.6E-34 T 05-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 K08M4_RS06565 a69baf6ec36ca0243d966f767b4d90b0 205 Gene3D G3DSA:3.40.50.1240 7 189 1.5E-35 T 05-07-2017 IPR029033 Histidine phosphatase superfamily K08M4_RS06565 a69baf6ec36ca0243d966f767b4d90b0 205 SUPERFAMILY SSF53254 7 189 1.41E-36 T 05-07-2017 IPR029033 Histidine phosphatase superfamily K08M4_RS14175 b2448ca3a7cd65e64236b6a1a1c9298a 146 Pfam PF00156 Phosphoribosyl transferase domain 49 143 6.4E-9 T 05-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 K08M4_RS14175 b2448ca3a7cd65e64236b6a1a1c9298a 146 Gene3D G3DSA:3.40.50.2020 1 145 5.6E-25 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS14175 b2448ca3a7cd65e64236b6a1a1c9298a 146 SUPERFAMILY SSF53271 2 143 6.82E-24 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS07590 a37c7ff4267a22ca3d89a317d4410e63 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 282 1.3E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07590 a37c7ff4267a22ca3d89a317d4410e63 285 SUPERFAMILY SSF161098 9 274 2.35E-53 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07590 a37c7ff4267a22ca3d89a317d4410e63 285 Gene3D G3DSA:1.10.3720.10 6 271 1.4E-48 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS09785 4c0b80ea3ff0cc1776b8eb95d64e2846 226 TIGRFAM TIGR00017 cmk: cytidylate kinase 6 219 2.5E-85 T 05-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 K08M4_RS09785 4c0b80ea3ff0cc1776b8eb95d64e2846 226 Hamap MF_00238 Cytidylate kinase [cmk]. 6 224 34.71 T 05-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 K08M4_RS09785 4c0b80ea3ff0cc1776b8eb95d64e2846 226 Pfam PF02224 Cytidylate kinase 8 221 2.5E-78 T 05-07-2017 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 K08M4_RS09785 4c0b80ea3ff0cc1776b8eb95d64e2846 226 Gene3D G3DSA:3.40.50.300 6 221 7.5E-77 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09785 4c0b80ea3ff0cc1776b8eb95d64e2846 226 SUPERFAMILY SSF52540 6 223 3.13E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01755 eca4c602471d08ff0fb989051000a78f 207 Gene3D G3DSA:3.40.50.1950 7 205 3.8E-74 T 05-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 K08M4_RS01755 eca4c602471d08ff0fb989051000a78f 207 Pfam PF02441 Flavoprotein 7 144 9.5E-24 T 05-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 K08M4_RS01755 eca4c602471d08ff0fb989051000a78f 207 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 8 201 1.3E-56 T 05-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 K08M4_RS01755 eca4c602471d08ff0fb989051000a78f 207 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 6 203 34.757 T 05-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 K08M4_RS01755 eca4c602471d08ff0fb989051000a78f 207 SUPERFAMILY SSF52507 6 202 2.49E-56 T 05-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 K08M4_RS09685 f3c91c814eb98119398e2b03c5b02345 403 Pfam PF00155 Aminotransferase class I and II 42 375 1.0E-51 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS09685 f3c91c814eb98119398e2b03c5b02345 403 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 4 380 44.572 T 05-07-2017 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 K08M4_RS09685 f3c91c814eb98119398e2b03c5b02345 403 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 232 241 - T 05-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 K08M4_RS09685 f3c91c814eb98119398e2b03c5b02345 403 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 21 376 2.3E-136 T 05-07-2017 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 K08M4_RS09685 f3c91c814eb98119398e2b03c5b02345 403 Gene3D G3DSA:3.40.640.10 59 268 1.7E-79 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS09685 f3c91c814eb98119398e2b03c5b02345 403 SUPERFAMILY SSF53383 4 379 9.58E-97 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS09685 f3c91c814eb98119398e2b03c5b02345 403 Gene3D G3DSA:3.90.1150.10 269 376 2.8E-20 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS00850 9719536f1750d8f6e6172e9942ef5bc3 355 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 142 158 - T 05-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS00850 9719536f1750d8f6e6172e9942ef5bc3 355 Gene3D G3DSA:3.20.20.210 2 353 8.2E-154 T 05-07-2017 K08M4_RS00850 9719536f1750d8f6e6172e9942ef5bc3 355 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 5 348 1.5E-140 T 05-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS00850 9719536f1750d8f6e6172e9942ef5bc3 355 SUPERFAMILY SSF51726 1 354 1.7E-121 T 05-07-2017 K08M4_RS00850 9719536f1750d8f6e6172e9942ef5bc3 355 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 350 50.222 T 05-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS00850 9719536f1750d8f6e6172e9942ef5bc3 355 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 9 347 2.3E-138 T 05-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS00850 9719536f1750d8f6e6172e9942ef5bc3 355 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 22 31 - T 05-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 K08M4_RS21570 3a599d9f5ddf94a7566966249a57d2dc 143 SUPERFAMILY SSF54427 8 128 2.42E-20 T 05-07-2017 IPR032710 NTF2-like domain K08M4_RS21570 3a599d9f5ddf94a7566966249a57d2dc 143 Pfam PF12680 SnoaL-like domain 12 112 6.5E-12 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain K08M4_RS21570 3a599d9f5ddf94a7566966249a57d2dc 143 Gene3D G3DSA:3.10.450.50 12 138 2.1E-15 T 05-07-2017 IPR032710 NTF2-like domain K08M4_RS21830 56c3c63cd512f38588cef86733448e67 357 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 163 275 3.2E-13 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain K08M4_RS21830 56c3c63cd512f38588cef86733448e67 357 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 6 143 3.5E-55 T 05-07-2017 K08M4_RS21830 56c3c63cd512f38588cef86733448e67 357 SUPERFAMILY SSF54593 6 341 7.01E-76 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS21830 56c3c63cd512f38588cef86733448e67 357 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 12 354 2.2E-129 T 05-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 K08M4_RS21830 56c3c63cd512f38588cef86733448e67 357 Gene3D G3DSA:3.10.180.10 159 354 2.3E-72 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS21830 56c3c63cd512f38588cef86733448e67 357 PIRSF PIRSF009283 1 355 2.3E-123 T 05-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 K08M4_RS21830 56c3c63cd512f38588cef86733448e67 357 Gene3D G3DSA:3.10.180.10 5 147 5.5E-42 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS05470 e435c044f8d44e7580954dd956d9a453 266 Pfam PF04288 MukE-like family 10 230 2.0E-115 T 05-07-2017 IPR007385 Prokaryotic chromosome segregation/condensation protein MukE GO:0005737|GO:0007059|GO:0030261 K08M4_RS05470 e435c044f8d44e7580954dd956d9a453 266 Hamap MF_01802 Chromosome partition protein MukE [mukE]. 10 242 48.253 T 05-07-2017 IPR007385 Prokaryotic chromosome segregation/condensation protein MukE GO:0005737|GO:0007059|GO:0030261 K08M4_RS05595 424911ce1c3db67066ec38888326e451 686 SUPERFAMILY SSF56935 51 686 4.03E-85 T 05-07-2017 K08M4_RS05595 424911ce1c3db67066ec38888326e451 686 Pfam PF07715 TonB-dependent Receptor Plug Domain 68 182 4.3E-10 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS05595 424911ce1c3db67066ec38888326e451 686 Gene3D G3DSA:2.170.130.10 47 184 1.0E-24 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS05595 424911ce1c3db67066ec38888326e451 686 Gene3D G3DSA:2.40.170.20 185 684 2.1E-64 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS05595 424911ce1c3db67066ec38888326e451 686 Pfam PF00593 TonB dependent receptor 447 682 6.3E-18 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS13460 e389519aaaf3689064ed1cf134c88d04 150 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 05-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13460 e389519aaaf3689064ed1cf134c88d04 150 Gene3D G3DSA:3.10.430.100 61 148 1.5E-25 T 05-07-2017 IPR020069 Ribosomal protein L9, C-terminal K08M4_RS13460 e389519aaaf3689064ed1cf134c88d04 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 3.8E-21 T 05-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS13460 e389519aaaf3689064ed1cf134c88d04 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 149 25.075 T 05-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS13460 e389519aaaf3689064ed1cf134c88d04 150 SUPERFAMILY SSF55653 60 148 2.09E-23 T 05-07-2017 IPR020069 Ribosomal protein L9, C-terminal K08M4_RS13460 e389519aaaf3689064ed1cf134c88d04 150 SUPERFAMILY SSF55658 1 57 4.53E-19 T 05-07-2017 IPR009027 Ribosomal protein L9/RNase H1, N-terminal K08M4_RS13460 e389519aaaf3689064ed1cf134c88d04 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 65 148 3.5E-23 T 05-07-2017 IPR020069 Ribosomal protein L9, C-terminal K08M4_RS13460 e389519aaaf3689064ed1cf134c88d04 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 148 9.0E-54 T 05-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS13460 e389519aaaf3689064ed1cf134c88d04 150 Gene3D G3DSA:3.40.5.10 1 52 2.1E-24 T 05-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS17205 7bc61a7ef61b18b938aac019b0163c86 520 SUPERFAMILY SSF55785 20 114 8.72E-25 T 05-07-2017 IPR000014 PAS domain K08M4_RS17205 7bc61a7ef61b18b938aac019b0163c86 520 Pfam PF08447 PAS fold 31 114 8.6E-13 T 05-07-2017 IPR013655 PAS fold-3 GO:0005515 K08M4_RS17205 7bc61a7ef61b18b938aac019b0163c86 520 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 112 6.6E-12 T 05-07-2017 IPR000014 PAS domain K08M4_RS17205 7bc61a7ef61b18b938aac019b0163c86 520 Gene3D G3DSA:1.10.287.950 271 489 1.2E-47 T 05-07-2017 K08M4_RS17205 7bc61a7ef61b18b938aac019b0163c86 520 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 316 517 1.3E-37 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS17205 7bc61a7ef61b18b938aac019b0163c86 520 SMART SM00283 257 518 9.6E-45 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS17205 7bc61a7ef61b18b938aac019b0163c86 520 SUPERFAMILY SSF58104 263 518 1.92E-59 T 05-07-2017 K08M4_RS17205 7bc61a7ef61b18b938aac019b0163c86 520 Gene3D G3DSA:3.30.450.20 19 113 3.4E-21 T 05-07-2017 K08M4_RS02570 b07d67892d4750e79a99f02c7bba3a6e 266 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 74 6.5E-15 T 05-07-2017 IPR002831 Transcription regulator TrmB, N-terminal K08M4_RS02570 b07d67892d4750e79a99f02c7bba3a6e 266 Pfam PF11495 Archaeal transcriptional regulator TrmB 108 214 5.1E-8 T 05-07-2017 IPR021586 Transcription regulator TrmB, C-terminal K08M4_RS02570 b07d67892d4750e79a99f02c7bba3a6e 266 SUPERFAMILY SSF46785 4 83 6.72E-8 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS02570 b07d67892d4750e79a99f02c7bba3a6e 266 Gene3D G3DSA:1.10.10.10 3 97 1.7E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS07395 1f9f215e77bd85c99b99f282c4abdd7d 109 Pfam PF01740 STAS domain 12 97 7.2E-10 T 05-07-2017 IPR002645 STAS domain K08M4_RS07395 1f9f215e77bd85c99b99f282c4abdd7d 109 Gene3D G3DSA:3.30.750.24 6 103 4.6E-21 T 05-07-2017 IPR002645 STAS domain K08M4_RS07395 1f9f215e77bd85c99b99f282c4abdd7d 109 SUPERFAMILY SSF52091 9 101 4.32E-19 T 05-07-2017 IPR002645 STAS domain K08M4_RS04150 3c115c313f64a28e68c6ad8ce3a1bd33 103 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 67 83 8.8E-13 T 05-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 K08M4_RS04150 3c115c313f64a28e68c6ad8ce3a1bd33 103 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 32 48 8.8E-13 T 05-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 K08M4_RS04150 3c115c313f64a28e68c6ad8ce3a1bd33 103 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 88 101 8.8E-13 T 05-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 K08M4_RS04150 3c115c313f64a28e68c6ad8ce3a1bd33 103 Pfam PF02049 Flagellar hook-basal body complex protein FliE 18 103 7.4E-29 T 05-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 K08M4_RS04150 3c115c313f64a28e68c6ad8ce3a1bd33 103 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 27 102 1.2E-18 T 05-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 K08M4_RS04150 3c115c313f64a28e68c6ad8ce3a1bd33 103 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 4 103 16.668 T 05-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 K08M4_RS03020 d62050a26b127926511e8f542c7006ff 431 Gene3D G3DSA:3.40.640.10 71 316 1.4E-79 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS03020 d62050a26b127926511e8f542c7006ff 431 Gene3D G3DSA:3.90.1150.10 2 69 2.2E-43 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS03020 d62050a26b127926511e8f542c7006ff 431 Gene3D G3DSA:3.90.1150.10 319 424 2.2E-43 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS03020 d62050a26b127926511e8f542c7006ff 431 SUPERFAMILY SSF53383 1 423 2.7E-131 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS03020 d62050a26b127926511e8f542c7006ff 431 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 426 103.879 T 05-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 K08M4_RS03020 d62050a26b127926511e8f542c7006ff 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 K08M4_RS03020 d62050a26b127926511e8f542c7006ff 431 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 3 424 7.7E-194 T 05-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 K08M4_RS03020 d62050a26b127926511e8f542c7006ff 431 Pfam PF00202 Aminotransferase class-III 33 396 9.4E-75 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 K08M4_RS11580 6fae09048b26c8f784b4b08dee4ac1ce 741 SUPERFAMILY SSF52540 34 183 1.62E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11580 6fae09048b26c8f784b4b08dee4ac1ce 741 SUPERFAMILY SSF52540 253 475 1.62E-43 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11580 6fae09048b26c8f784b4b08dee4ac1ce 741 Gene3D G3DSA:3.40.50.300 660 719 5.0E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11580 6fae09048b26c8f784b4b08dee4ac1ce 741 SUPERFAMILY SSF52540 462 493 2.57E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11580 6fae09048b26c8f784b4b08dee4ac1ce 741 SUPERFAMILY SSF52540 389 430 2.57E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11580 6fae09048b26c8f784b4b08dee4ac1ce 741 SUPERFAMILY SSF52540 556 738 2.57E-59 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11580 6fae09048b26c8f784b4b08dee4ac1ce 741 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 39 737 48.054 T 05-07-2017 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 K08M4_RS11580 6fae09048b26c8f784b4b08dee4ac1ce 741 Pfam PF13604 AAA domain 264 424 3.3E-30 T 05-07-2017 K08M4_RS11580 6fae09048b26c8f784b4b08dee4ac1ce 741 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 32 739 9.9E-204 T 05-07-2017 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 K08M4_RS11580 6fae09048b26c8f784b4b08dee4ac1ce 741 Gene3D G3DSA:3.40.50.300 259 427 3.1E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11580 6fae09048b26c8f784b4b08dee4ac1ce 741 Gene3D G3DSA:3.40.50.300 465 496 3.1E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11580 6fae09048b26c8f784b4b08dee4ac1ce 741 Pfam PF13538 UvrD-like helicase C-terminal domain 668 713 9.1E-14 T 05-07-2017 IPR027785 UvrD-like helicase C-terminal domain K08M4_RS14230 60f94f0b56f495315d9e2d100771f862 147 SUPERFAMILY SSF54523 36 142 4.08E-38 T 05-07-2017 K08M4_RS14230 60f94f0b56f495315d9e2d100771f862 147 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 31 5.7E-9 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS14230 60f94f0b56f495315d9e2d100771f862 147 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 9 142 4.7E-57 T 05-07-2017 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 K08M4_RS14230 60f94f0b56f495315d9e2d100771f862 147 Pfam PF08334 Type II secretion system (T2SS), protein G 33 141 1.6E-42 T 05-07-2017 IPR013545 Type II secretion system protein G K08M4_RS14230 60f94f0b56f495315d9e2d100771f862 147 Gene3D G3DSA:3.30.700.10 11 78 2.2E-8 T 05-07-2017 K08M4_RS14230 60f94f0b56f495315d9e2d100771f862 147 PRINTS PR00813 Bacterial general secretion pathway protein G signature 46 64 4.2E-22 T 05-07-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 K08M4_RS14230 60f94f0b56f495315d9e2d100771f862 147 PRINTS PR00813 Bacterial general secretion pathway protein G signature 10 35 4.2E-22 T 05-07-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 K08M4_RS14230 60f94f0b56f495315d9e2d100771f862 147 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 5 28 3.6E-9 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS14230 60f94f0b56f495315d9e2d100771f862 147 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS17260 02cd58f64c63b8b55a1803bcf2726067 397 Gene3D G3DSA:3.40.50.300 147 348 3.3E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17260 02cd58f64c63b8b55a1803bcf2726067 397 Pfam PF13614 AAA domain 149 315 2.2E-7 T 05-07-2017 IPR025669 AAA domain K08M4_RS17260 02cd58f64c63b8b55a1803bcf2726067 397 SUPERFAMILY SSF52540 148 337 8.26E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00465 3740d1dab8f21edf26690af73b652e35 155 Pfam PF01878 EVE domain 2 148 2.8E-56 T 05-07-2017 IPR002740 EVE domain K08M4_RS00465 3740d1dab8f21edf26690af73b652e35 155 SUPERFAMILY SSF88697 1 148 6.13E-61 T 05-07-2017 IPR015947 PUA-like domain K08M4_RS00465 3740d1dab8f21edf26690af73b652e35 155 Gene3D G3DSA:3.10.590.10 1 148 6.8E-33 T 05-07-2017 IPR002740 EVE domain K08M4_RS02770 f0e41bd6cadea738d25dc5374055ca27 65 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 4 60 17.869 T 05-07-2017 IPR005584 DNA gyrase inhibitor YacG GO:0008270 K08M4_RS02770 f0e41bd6cadea738d25dc5374055ca27 65 SUPERFAMILY SSF57716 5 63 3.14E-20 T 05-07-2017 K08M4_RS02770 f0e41bd6cadea738d25dc5374055ca27 65 Gene3D G3DSA:3.30.50.10 2 63 1.5E-24 T 05-07-2017 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 K08M4_RS02770 f0e41bd6cadea738d25dc5374055ca27 65 Pfam PF03884 Domain of unknown function (DUF329) 8 58 1.3E-23 T 05-07-2017 IPR005584 DNA gyrase inhibitor YacG GO:0008270 K08M4_RS15530 232dbe5ccf595938e3380c7948da1274 507 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 253 1.0E-84 T 05-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 K08M4_RS15530 232dbe5ccf595938e3380c7948da1274 507 PIRSF PIRSF000538 4 503 2.4E-175 T 05-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 K08M4_RS15530 232dbe5ccf595938e3380c7948da1274 507 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 451 2.7E-59 T 05-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 K08M4_RS15530 232dbe5ccf595938e3380c7948da1274 507 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 136 148 - T 05-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 K08M4_RS15530 232dbe5ccf595938e3380c7948da1274 507 Gene3D G3DSA:3.30.420.40 2 254 8.3E-105 T 05-07-2017 K08M4_RS15530 232dbe5ccf595938e3380c7948da1274 507 Gene3D G3DSA:3.30.420.40 255 498 4.9E-101 T 05-07-2017 K08M4_RS15530 232dbe5ccf595938e3380c7948da1274 507 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 497 6.6E-225 T 05-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 K08M4_RS15530 232dbe5ccf595938e3380c7948da1274 507 SUPERFAMILY SSF53067 255 495 1.54E-84 T 05-07-2017 K08M4_RS15530 232dbe5ccf595938e3380c7948da1274 507 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 363 383 - T 05-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 K08M4_RS15530 232dbe5ccf595938e3380c7948da1274 507 SUPERFAMILY SSF53067 5 256 2.22E-93 T 05-07-2017 K08M4_RS15530 232dbe5ccf595938e3380c7948da1274 507 Hamap MF_00186 Glycerol kinase [glpK]. 4 498 58.022 T 05-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 K08M4_RS07040 d867ba6b44effe86aebd7510f8ea7e5a 124 Gene3D G3DSA:3.10.180.10 11 121 7.8E-28 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS07040 d867ba6b44effe86aebd7510f8ea7e5a 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 116 4.6E-5 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain K08M4_RS07040 d867ba6b44effe86aebd7510f8ea7e5a 124 SUPERFAMILY SSF54593 12 120 2.95E-24 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS11605 7e7fa1efa6477fd58cf4ce35d74dc894 97 Pfam PF07130 YebG protein 1 72 5.6E-32 T 05-07-2017 IPR009813 Uncharacterised protein family YebG K08M4_RS11605 7e7fa1efa6477fd58cf4ce35d74dc894 97 Gene3D G3DSA:1.10.10.710 20 85 8.1E-26 T 05-07-2017 IPR009813 Uncharacterised protein family YebG K08M4_RS18475 9ec862ce2b9eec2dd4d166d73d311847 316 SMART SM00267 133 309 5.3E-56 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS18475 9ec862ce2b9eec2dd4d166d73d311847 316 Pfam PF00990 Diguanylate cyclase, GGDEF domain 144 305 3.3E-44 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS18475 9ec862ce2b9eec2dd4d166d73d311847 316 Gene3D G3DSA:3.40.50.2300 1 143 5.4E-35 T 05-07-2017 K08M4_RS18475 9ec862ce2b9eec2dd4d166d73d311847 316 SUPERFAMILY SSF52172 1 149 2.42E-37 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS18475 9ec862ce2b9eec2dd4d166d73d311847 316 SMART SM00448 1 113 1.8E-34 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS18475 9ec862ce2b9eec2dd4d166d73d311847 316 Gene3D G3DSA:3.30.70.270 147 307 7.4E-46 T 05-07-2017 K08M4_RS18475 9ec862ce2b9eec2dd4d166d73d311847 316 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 140 307 8.6E-47 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS18475 9ec862ce2b9eec2dd4d166d73d311847 316 Pfam PF00072 Response regulator receiver domain 3 112 3.8E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS18475 9ec862ce2b9eec2dd4d166d73d311847 316 SUPERFAMILY SSF55073 149 307 4.24E-43 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS04805 12e92afacad8f33ec357653c3bccbbb6 227 SUPERFAMILY SSF51735 1 197 3.61E-23 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04805 12e92afacad8f33ec357653c3bccbbb6 227 Gene3D G3DSA:3.40.50.720 2 189 3.4E-23 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04805 12e92afacad8f33ec357653c3bccbbb6 227 Pfam PF00106 short chain dehydrogenase 7 189 6.2E-15 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS04805 12e92afacad8f33ec357653c3bccbbb6 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 4.8E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS04805 12e92afacad8f33ec357653c3bccbbb6 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.8E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS04805 12e92afacad8f33ec357653c3bccbbb6 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.8E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS04805 12e92afacad8f33ec357653c3bccbbb6 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.8E-5 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS09950 968beb02988205c4a459b3b732cb9098 311 Gene3D G3DSA:3.40.190.10 284 299 2.3E-13 T 05-07-2017 K08M4_RS09950 968beb02988205c4a459b3b732cb9098 311 Gene3D G3DSA:3.40.190.10 90 177 2.3E-13 T 05-07-2017 K08M4_RS09950 968beb02988205c4a459b3b732cb9098 311 SUPERFAMILY SSF46785 4 86 1.25E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS09950 968beb02988205c4a459b3b732cb9098 311 Gene3D G3DSA:1.10.10.10 4 86 2.5E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS09950 968beb02988205c4a459b3b732cb9098 311 SUPERFAMILY SSF53850 90 294 2.9E-32 T 05-07-2017 K08M4_RS09950 968beb02988205c4a459b3b732cb9098 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 5.2E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS09950 968beb02988205c4a459b3b732cb9098 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 5.2E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS09950 968beb02988205c4a459b3b732cb9098 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 5.2E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS09950 968beb02988205c4a459b3b732cb9098 311 Gene3D G3DSA:3.40.190.10 178 266 4.5E-20 T 05-07-2017 K08M4_RS09950 968beb02988205c4a459b3b732cb9098 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 2.3E-17 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS09950 968beb02988205c4a459b3b732cb9098 311 Pfam PF03466 LysR substrate binding domain 98 293 9.2E-15 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS13740 dba9c0e3317585e58c90f40b06916d1b 510 Pfam PF01676 Metalloenzyme superfamily 5 496 2.2E-79 T 05-07-2017 IPR006124 Metalloenzyme GO:0003824|GO:0046872 K08M4_RS13740 dba9c0e3317585e58c90f40b06916d1b 510 Gene3D G3DSA:3.40.720.10 5 78 1.8E-85 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 K08M4_RS13740 dba9c0e3317585e58c90f40b06916d1b 510 Gene3D G3DSA:3.40.720.10 313 509 1.8E-85 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 K08M4_RS13740 dba9c0e3317585e58c90f40b06916d1b 510 PIRSF PIRSF001492 1 510 2.4E-199 T 05-07-2017 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS13740 dba9c0e3317585e58c90f40b06916d1b 510 SUPERFAMILY SSF53649 309 508 7.85E-74 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 K08M4_RS13740 dba9c0e3317585e58c90f40b06916d1b 510 SUPERFAMILY SSF53649 5 78 7.85E-74 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 K08M4_RS13740 dba9c0e3317585e58c90f40b06916d1b 510 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 5 508 3.2E-225 T 05-07-2017 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS13740 dba9c0e3317585e58c90f40b06916d1b 510 Gene3D G3DSA:3.40.1450.10 79 308 1.4E-92 T 05-07-2017 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS13740 dba9c0e3317585e58c90f40b06916d1b 510 SUPERFAMILY SSF64158 78 308 4.18E-80 T 05-07-2017 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS13740 dba9c0e3317585e58c90f40b06916d1b 510 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 83 297 1.2E-78 T 05-07-2017 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS13740 dba9c0e3317585e58c90f40b06916d1b 510 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 5 510 49.157 T 05-07-2017 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS06020 0540f9be8dc95173b81342ce9d330c95 1011 Gene3D G3DSA:3.30.43.10 14 109 4.3E-24 T 05-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 K08M4_RS06020 0540f9be8dc95173b81342ce9d330c95 1011 Gene3D G3DSA:3.30.465.10 110 277 4.6E-39 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 K08M4_RS06020 0540f9be8dc95173b81342ce9d330c95 1011 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 667 678 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS06020 0540f9be8dc95173b81342ce9d330c95 1011 Pfam PF01565 FAD binding domain 52 191 1.2E-34 T 05-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 K08M4_RS06020 0540f9be8dc95173b81342ce9d330c95 1011 SUPERFAMILY SSF56176 25 192 9.0E-50 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 K08M4_RS06020 0540f9be8dc95173b81342ce9d330c95 1011 SUPERFAMILY SSF56176 235 277 9.0E-50 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 K08M4_RS06020 0540f9be8dc95173b81342ce9d330c95 1011 Pfam PF02913 FAD linked oxidases, C-terminal domain 276 534 1.0E-63 T 05-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 K08M4_RS06020 0540f9be8dc95173b81342ce9d330c95 1011 SUPERFAMILY SSF46548 647 685 1.99E-6 T 05-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 K08M4_RS06020 0540f9be8dc95173b81342ce9d330c95 1011 SUPERFAMILY SSF46548 571 617 1.99E-6 T 05-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 K08M4_RS06020 0540f9be8dc95173b81342ce9d330c95 1011 SUPERFAMILY SSF55103 252 537 1.8E-53 T 05-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 K08M4_RS06020 0540f9be8dc95173b81342ce9d330c95 1011 Gene3D G3DSA:1.10.1060.10 646 694 5.6E-14 T 05-07-2017 K08M4_RS06020 0540f9be8dc95173b81342ce9d330c95 1011 Gene3D G3DSA:1.10.1060.10 511 614 5.6E-14 T 05-07-2017 K08M4_RS06020 0540f9be8dc95173b81342ce9d330c95 1011 Pfam PF13183 4Fe-4S dicluster domain 570 681 1.3E-11 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain K08M4_RS16730 68a089744280e01fcf043b809d828979 209 SUPERFAMILY SSF110111 71 192 3.92E-44 T 05-07-2017 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16730 68a089744280e01fcf043b809d828979 209 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 45 189 1.4E-46 T 05-07-2017 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 K08M4_RS16730 68a089744280e01fcf043b809d828979 209 PIRSF PIRSF005413 6 206 2.2E-65 T 05-07-2017 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 K08M4_RS16730 68a089744280e01fcf043b809d828979 209 Gene3D G3DSA:2.60.370.10 71 200 4.3E-46 T 05-07-2017 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 SMART SM00836 461 577 1.7E-41 T 05-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 SUPERFAMILY SSF52374 111 455 3.31E-92 T 05-07-2017 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 SUPERFAMILY SSF47323 455 577 5.1E-36 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 Pfam PF00750 tRNA synthetases class I (R) 98 447 1.7E-160 T 05-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 577 28.094 T 05-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 SMART SM01016 5 87 2.6E-28 T 05-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 3 577 9.6E-199 T 05-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 Gene3D G3DSA:3.40.50.620 111 454 2.1E-113 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 Gene3D G3DSA:1.10.730.10 455 577 7.6E-39 T 05-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 114 129 3.6E-25 T 05-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 129 145 3.6E-25 T 05-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 153 166 3.6E-25 T 05-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 304 325 3.6E-25 T 05-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 122 133 - T 05-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 Pfam PF05746 DALR anticodon binding domain 461 577 2.7E-37 T 05-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 7 87 3.0E-20 T 05-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 SUPERFAMILY SSF55190 2 96 6.28E-22 T 05-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 K08M4_RS10510 70654025fd15257142093c386d3a8a6a 577 Gene3D G3DSA:3.30.1360.70 2 105 1.3E-33 T 05-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 K08M4_RS17125 ba535fb492438dc1a6aaf620b314b1b4 358 Pfam PF01212 Beta-eliminating lyase 26 291 6.7E-34 T 05-07-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 K08M4_RS17125 ba535fb492438dc1a6aaf620b314b1b4 358 Gene3D G3DSA:3.40.640.10 20 236 9.9E-40 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS17125 ba535fb492438dc1a6aaf620b314b1b4 358 SUPERFAMILY SSF53383 22 316 9.65E-73 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS16835 184fd0fbe1c9a7f3684f7829f1280876 350 PIRSF PIRSF001361 1 350 5.9E-162 T 05-07-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 K08M4_RS16835 184fd0fbe1c9a7f3684f7829f1280876 350 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 5 348 5.4E-169 T 05-07-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 K08M4_RS16835 184fd0fbe1c9a7f3684f7829f1280876 350 Gene3D G3DSA:3.20.20.70 8 349 1.0E-157 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS16835 184fd0fbe1c9a7f3684f7829f1280876 350 SUPERFAMILY SSF51569 6 347 1.26E-137 T 05-07-2017 K08M4_RS16835 184fd0fbe1c9a7f3684f7829f1280876 350 Pfam PF00793 DAHP synthetase I family 41 337 1.7E-105 T 05-07-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 K08M4_RS01285 2708397732ab64d40d1037d494917570 362 Gene3D G3DSA:3.40.50.1970 2 172 9.5E-66 T 05-07-2017 K08M4_RS01285 2708397732ab64d40d1037d494917570 362 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 358 43.12 T 05-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 K08M4_RS01285 2708397732ab64d40d1037d494917570 362 PIRSF PIRSF001455 16 360 3.0E-108 T 05-07-2017 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 K08M4_RS01285 2708397732ab64d40d1037d494917570 362 SUPERFAMILY SSF56796 4 356 4.84E-117 T 05-07-2017 K08M4_RS01285 2708397732ab64d40d1037d494917570 362 Pfam PF01761 3-dehydroquinate synthase 68 325 1.2E-111 T 05-07-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 K08M4_RS01285 2708397732ab64d40d1037d494917570 362 Gene3D G3DSA:1.20.1090.10 173 356 2.8E-68 T 05-07-2017 K08M4_RS01285 2708397732ab64d40d1037d494917570 362 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 355 2.7E-121 T 05-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 K08M4_RS16620 126fd1058e9cf4a73541c8d77b3ea3bf 387 Pfam PF12146 Serine aminopeptidase, S33 85 198 6.1E-13 T 05-07-2017 IPR022742 Serine aminopeptidase, S33 K08M4_RS16620 126fd1058e9cf4a73541c8d77b3ea3bf 387 Gene3D G3DSA:3.40.50.1820 77 282 4.4E-32 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS16620 126fd1058e9cf4a73541c8d77b3ea3bf 387 SUPERFAMILY SSF53474 76 284 3.19E-25 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS11410 e6536d0b9a7d3a07861f8d5a24e6ef06 752 SMART SM00028 248 281 23.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS11410 e6536d0b9a7d3a07861f8d5a24e6ef06 752 SMART SM00028 328 361 44.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS11410 e6536d0b9a7d3a07861f8d5a24e6ef06 752 SMART SM00028 168 201 460.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS11410 e6536d0b9a7d3a07861f8d5a24e6ef06 752 SMART SM00028 288 321 0.033 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS11410 e6536d0b9a7d3a07861f8d5a24e6ef06 752 SMART SM00028 82 115 0.29 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS11410 e6536d0b9a7d3a07861f8d5a24e6ef06 752 SUPERFAMILY SSF48452 328 433 1.9E-7 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS11410 e6536d0b9a7d3a07861f8d5a24e6ef06 752 SUPERFAMILY SSF48452 171 359 2.72E-16 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS11410 e6536d0b9a7d3a07861f8d5a24e6ef06 752 Gene3D G3DSA:1.25.40.10 177 437 1.2E-15 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS06995 e3aaf00ce0e78d3aa57b3e4690647868 157 SMART SM01022 30 153 9.4E-38 T 05-07-2017 IPR007374 ASCH domain K08M4_RS06995 e3aaf00ce0e78d3aa57b3e4690647868 157 Pfam PF04266 ASCH domain 42 153 7.5E-24 T 05-07-2017 IPR007374 ASCH domain K08M4_RS06995 e3aaf00ce0e78d3aa57b3e4690647868 157 SUPERFAMILY SSF88697 3 153 2.21E-51 T 05-07-2017 IPR015947 PUA-like domain K08M4_RS06995 e3aaf00ce0e78d3aa57b3e4690647868 157 PIRSF PIRSF021320 1 156 8.1E-45 T 05-07-2017 IPR009326 Protein of unknown function DUF984 K08M4_RS06995 e3aaf00ce0e78d3aa57b3e4690647868 157 Gene3D G3DSA:3.10.400.10 3 154 8.6E-55 T 05-07-2017 K08M4_RS12490 fd2fb8cae1a54d29d69d43fd8c1d7a09 317 Pfam PF03186 CobD/Cbib protein 19 283 1.1E-34 T 05-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 K08M4_RS05475 2b705f3d64e3bbf6fea08aff4ce272ae 1484 SUPERFAMILY SSF52540 26 224 3.19E-22 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05475 2b705f3d64e3bbf6fea08aff4ce272ae 1484 SUPERFAMILY SSF52540 1284 1434 7.86E-6 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05475 2b705f3d64e3bbf6fea08aff4ce272ae 1484 SUPERFAMILY SSF52540 21 55 7.86E-6 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05475 2b705f3d64e3bbf6fea08aff4ce272ae 1484 PIRSF PIRSF005246 1 1483 0.0 T 05-07-2017 IPR012090 Chromosome partition protein MukB GO:0003677|GO:0005524|GO:0007059|GO:0009295|GO:0030261 K08M4_RS05475 2b705f3d64e3bbf6fea08aff4ce272ae 1484 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1337 1425 1.4E-14 T 05-07-2017 K08M4_RS05475 2b705f3d64e3bbf6fea08aff4ce272ae 1484 Pfam PF16330 MukB hinge domain 646 811 4.3E-71 T 05-07-2017 IPR032520 MukB, hinge domain K08M4_RS05475 2b705f3d64e3bbf6fea08aff4ce272ae 1484 Gene3D G3DSA:3.40.1140.10 1 225 1.4E-43 T 05-07-2017 K08M4_RS05475 2b705f3d64e3bbf6fea08aff4ce272ae 1484 Pfam PF04310 MukB N-terminal 2 227 5.3E-120 T 05-07-2017 IPR007406 MukB, N-terminal domain GO:0003677|GO:0005524|GO:0007059|GO:0009295|GO:0030261 K08M4_RS00310 d84315ea39b014b2622ce4ac5df25c91 237 SUPERFAMILY SSF63380 2 101 6.96E-17 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 K08M4_RS00310 d84315ea39b014b2622ce4ac5df25c91 237 SUPERFAMILY SSF52343 104 235 1.83E-34 T 05-07-2017 K08M4_RS00310 d84315ea39b014b2622ce4ac5df25c91 237 Gene3D G3DSA:3.40.50.80 104 235 1.3E-37 T 05-07-2017 K08M4_RS00310 d84315ea39b014b2622ce4ac5df25c91 237 Pfam PF00175 Oxidoreductase NAD-binding domain 112 215 1.1E-22 T 05-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 K08M4_RS00310 d84315ea39b014b2622ce4ac5df25c91 237 PRINTS PR00410 Phenol hydroxylase reductase family signature 46 53 3.1E-14 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 K08M4_RS00310 d84315ea39b014b2622ce4ac5df25c91 237 PRINTS PR00410 Phenol hydroxylase reductase family signature 111 130 3.1E-14 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 K08M4_RS00310 d84315ea39b014b2622ce4ac5df25c91 237 PRINTS PR00410 Phenol hydroxylase reductase family signature 136 145 3.1E-14 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 K08M4_RS00310 d84315ea39b014b2622ce4ac5df25c91 237 PRINTS PR00410 Phenol hydroxylase reductase family signature 30 42 3.1E-14 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 K08M4_RS00310 d84315ea39b014b2622ce4ac5df25c91 237 PRINTS PR00410 Phenol hydroxylase reductase family signature 95 104 3.1E-14 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 K08M4_RS00310 d84315ea39b014b2622ce4ac5df25c91 237 Gene3D G3DSA:2.40.30.10 1 101 1.3E-27 T 05-07-2017 K08M4_RS00310 d84315ea39b014b2622ce4ac5df25c91 237 Pfam PF00970 Oxidoreductase FAD-binding domain 14 98 1.3E-4 T 05-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 K08M4_RS15435 1d5d94bf68d132e9edf9a0dfbc04a7c3 299 Pfam PF00892 EamA-like transporter family 6 133 3.7E-17 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS15435 1d5d94bf68d132e9edf9a0dfbc04a7c3 299 Pfam PF00892 EamA-like transporter family 147 278 2.1E-15 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS15435 1d5d94bf68d132e9edf9a0dfbc04a7c3 299 SUPERFAMILY SSF103481 184 278 6.93E-13 T 05-07-2017 K08M4_RS15435 1d5d94bf68d132e9edf9a0dfbc04a7c3 299 SUPERFAMILY SSF103481 37 135 5.1E-14 T 05-07-2017 K08M4_RS20870 5f09fc5c3d29775402d1bab5900ac764 280 Pfam PF12833 Helix-turn-helix domain 31 106 1.5E-16 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS20870 5f09fc5c3d29775402d1bab5900ac764 280 Gene3D G3DSA:1.10.10.60 3 54 1.9E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20870 5f09fc5c3d29775402d1bab5900ac764 280 SUPERFAMILY SSF46689 60 107 1.25E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20870 5f09fc5c3d29775402d1bab5900ac764 280 SMART SM00871 126 280 7.0E-39 T 05-07-2017 IPR010499 Bacterial transcription activator, effector binding K08M4_RS20870 5f09fc5c3d29775402d1bab5900ac764 280 SMART SM00342 22 105 1.0E-18 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS20870 5f09fc5c3d29775402d1bab5900ac764 280 Gene3D G3DSA:1.10.10.60 60 108 3.3E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20870 5f09fc5c3d29775402d1bab5900ac764 280 Pfam PF06445 GyrI-like small molecule binding domain 126 280 4.7E-37 T 05-07-2017 IPR029442 GyrI-like small molecule binding domain K08M4_RS20870 5f09fc5c3d29775402d1bab5900ac764 280 Gene3D G3DSA:3.20.80.10 126 280 2.1E-44 T 05-07-2017 IPR011256 Regulatory factor, effector binding domain K08M4_RS20870 5f09fc5c3d29775402d1bab5900ac764 280 SUPERFAMILY SSF55136 126 280 3.14E-37 T 05-07-2017 IPR011256 Regulatory factor, effector binding domain K08M4_RS20870 5f09fc5c3d29775402d1bab5900ac764 280 SUPERFAMILY SSF46689 5 55 1.08E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS09890 2cf5c985645ec6aa242d7e5c42fff03a 663 SMART SM00283 401 662 1.5E-75 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS09890 2cf5c985645ec6aa242d7e5c42fff03a 663 SUPERFAMILY SSF58104 354 663 1.11E-73 T 05-07-2017 K08M4_RS09890 2cf5c985645ec6aa242d7e5c42fff03a 663 SMART SM00304 334 386 2.8E-4 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS09890 2cf5c985645ec6aa242d7e5c42fff03a 663 Gene3D G3DSA:1.10.287.950 416 632 4.7E-55 T 05-07-2017 K08M4_RS09890 2cf5c985645ec6aa242d7e5c42fff03a 663 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 458 661 1.8E-50 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS09890 2cf5c985645ec6aa242d7e5c42fff03a 663 Pfam PF00672 HAMP domain 315 382 4.2E-8 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS15520 c052c73d425ee4b8de13742ddce480b2 519 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 21 38 - T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 K08M4_RS15520 c052c73d425ee4b8de13742ddce480b2 519 Pfam PF01266 FAD dependent oxidoreductase 17 335 3.9E-43 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 K08M4_RS15520 c052c73d425ee4b8de13742ddce480b2 519 SUPERFAMILY SSF51905 15 272 1.0E-29 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS15520 c052c73d425ee4b8de13742ddce480b2 519 SUPERFAMILY SSF51905 324 334 1.0E-29 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS15520 c052c73d425ee4b8de13742ddce480b2 519 Gene3D G3DSA:3.50.50.60 14 314 8.9E-36 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS15520 c052c73d425ee4b8de13742ddce480b2 519 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 29 39 4.6E-29 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 K08M4_RS15520 c052c73d425ee4b8de13742ddce480b2 519 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 325 331 4.6E-29 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 K08M4_RS15520 c052c73d425ee4b8de13742ddce480b2 519 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 16 28 4.6E-29 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 K08M4_RS15520 c052c73d425ee4b8de13742ddce480b2 519 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 90 102 4.6E-29 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 K08M4_RS15520 c052c73d425ee4b8de13742ddce480b2 519 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 359 371 4.6E-29 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 K08M4_RS15520 c052c73d425ee4b8de13742ddce480b2 519 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 45 57 4.6E-29 T 05-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 K08M4_RS15520 c052c73d425ee4b8de13742ddce480b2 519 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 393 501 2.9E-9 T 05-07-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 K08M4_RS17990 eab13456bc559d02e5f10add3c243a94 681 SUPERFAMILY SSF48371 38 253 1.86E-6 T 05-07-2017 IPR016024 Armadillo-type fold GO:0005488 K08M4_RS17990 eab13456bc559d02e5f10add3c243a94 681 Gene3D G3DSA:1.25.10.10 22 252 1.9E-6 T 05-07-2017 IPR011989 Armadillo-like helical K08M4_RS04170 4dd538fc3a5dd8c10a2a54f05c2684c9 439 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 146 357 4.6E-74 T 05-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS04170 4dd538fc3a5dd8c10a2a54f05c2684c9 439 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 22 437 7.0E-176 T 05-07-2017 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS04170 4dd538fc3a5dd8c10a2a54f05c2684c9 439 SMART SM00382 158 342 2.3E-6 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS04170 4dd538fc3a5dd8c10a2a54f05c2684c9 439 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 348 357 - T 05-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS04170 4dd538fc3a5dd8c10a2a54f05c2684c9 439 SUPERFAMILY SSF52540 93 362 1.67E-96 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04170 4dd538fc3a5dd8c10a2a54f05c2684c9 439 Gene3D G3DSA:3.40.50.300 94 359 3.3E-93 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04170 4dd538fc3a5dd8c10a2a54f05c2684c9 439 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 24 435 1.1E-195 T 05-07-2017 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 K08M4_RS05890 f49d059ac13dcd4ac343a5333f28f635 124 SUPERFAMILY SSF54427 1 117 6.9E-21 T 05-07-2017 IPR032710 NTF2-like domain K08M4_RS05890 f49d059ac13dcd4ac343a5333f28f635 124 Pfam PF12680 SnoaL-like domain 16 92 7.4E-9 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain K08M4_RS05890 f49d059ac13dcd4ac343a5333f28f635 124 Gene3D G3DSA:3.10.450.50 5 75 8.6E-11 T 05-07-2017 IPR032710 NTF2-like domain K08M4_RS10580 009c4ab3694455128489adcd0c0b363b 588 Pfam PF02910 Fumarate reductase flavoprotein C-term 460 588 6.2E-37 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS10580 009c4ab3694455128489adcd0c0b363b 588 Pfam PF00890 FAD binding domain 9 405 5.2E-117 T 05-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS10580 009c4ab3694455128489adcd0c0b363b 588 SUPERFAMILY SSF56425 237 356 2.54E-41 T 05-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS10580 009c4ab3694455128489adcd0c0b363b 588 Gene3D G3DSA:1.20.58.100 433 547 8.0E-38 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS10580 009c4ab3694455128489adcd0c0b363b 588 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 43 52 - T 05-07-2017 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS10580 009c4ab3694455128489adcd0c0b363b 588 Gene3D G3DSA:3.90.700.10 243 349 4.2E-41 T 05-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS10580 009c4ab3694455128489adcd0c0b363b 588 Gene3D G3DSA:3.50.50.60 351 426 9.0E-115 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS10580 009c4ab3694455128489adcd0c0b363b 588 Gene3D G3DSA:3.50.50.60 6 242 9.0E-115 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS10580 009c4ab3694455128489adcd0c0b363b 588 SUPERFAMILY SSF46977 452 588 1.28E-46 T 05-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS10580 009c4ab3694455128489adcd0c0b363b 588 Gene3D G3DSA:4.10.80.40 548 588 1.0E-20 T 05-07-2017 K08M4_RS10580 009c4ab3694455128489adcd0c0b363b 588 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 6 588 2.0E-273 T 05-07-2017 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS10580 009c4ab3694455128489adcd0c0b363b 588 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 9 588 8.0E-239 T 05-07-2017 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS10580 009c4ab3694455128489adcd0c0b363b 588 PIRSF PIRSF000171 1 580 1.3E-52 T 05-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS10580 009c4ab3694455128489adcd0c0b363b 588 SUPERFAMILY SSF51905 359 444 4.26E-72 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS10580 009c4ab3694455128489adcd0c0b363b 588 SUPERFAMILY SSF51905 5 259 4.26E-72 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS08650 377bfd6ec970aa974730adfdc0749a63 284 SUPERFAMILY SSF53697 93 280 6.88E-39 T 05-07-2017 K08M4_RS08650 377bfd6ec970aa974730adfdc0749a63 284 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 1.0E-28 T 05-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 K08M4_RS08650 377bfd6ec970aa974730adfdc0749a63 284 SUPERFAMILY SSF46689 1 80 1.58E-21 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS08650 377bfd6ec970aa974730adfdc0749a63 284 Gene3D G3DSA:3.40.50.10490 96 269 7.4E-37 T 05-07-2017 K08M4_RS08650 377bfd6ec970aa974730adfdc0749a63 284 Gene3D G3DSA:1.10.10.10 1 80 2.5E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS08650 377bfd6ec970aa974730adfdc0749a63 284 Pfam PF01380 SIS domain 124 252 6.8E-25 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 K08M4_RS17390 9dfa5a0c554a88a783f168a559e82b0f 302 SUPERFAMILY SSF46689 7 57 5.38E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS17390 9dfa5a0c554a88a783f168a559e82b0f 302 Gene3D G3DSA:3.20.80.10 133 300 1.9E-17 T 05-07-2017 IPR011256 Regulatory factor, effector binding domain K08M4_RS17390 9dfa5a0c554a88a783f168a559e82b0f 302 Gene3D G3DSA:1.10.10.60 60 114 3.4E-18 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS17390 9dfa5a0c554a88a783f168a559e82b0f 302 SUPERFAMILY SSF55136 136 301 1.74E-20 T 05-07-2017 IPR011256 Regulatory factor, effector binding domain K08M4_RS17390 9dfa5a0c554a88a783f168a559e82b0f 302 Gene3D G3DSA:1.10.10.60 8 59 2.1E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS17390 9dfa5a0c554a88a783f168a559e82b0f 302 Pfam PF12833 Helix-turn-helix domain 29 107 2.2E-22 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS17390 9dfa5a0c554a88a783f168a559e82b0f 302 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 60 102 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 K08M4_RS17390 9dfa5a0c554a88a783f168a559e82b0f 302 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 90 106 4.5E-7 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS17390 9dfa5a0c554a88a783f168a559e82b0f 302 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 75 90 4.5E-7 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS17390 9dfa5a0c554a88a783f168a559e82b0f 302 SUPERFAMILY SSF46689 60 109 4.93E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS17390 9dfa5a0c554a88a783f168a559e82b0f 302 SMART SM00871 135 300 4.7E-15 T 05-07-2017 IPR010499 Bacterial transcription activator, effector binding K08M4_RS17390 9dfa5a0c554a88a783f168a559e82b0f 302 SMART SM00342 23 106 4.1E-27 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS17390 9dfa5a0c554a88a783f168a559e82b0f 302 Pfam PF14526 Integron-associated effector binding protein 138 299 1.6E-15 T 05-07-2017 IPR029441 Integron-associated effector binding protein K08M4_RS21765 5d8dda1ff7eb728ad421df3093adb79b 202 Pfam PF11736 Protein of unknown function (DUF3299) 24 201 5.0E-30 T 05-07-2017 IPR021727 Protein of unknown function DUF3299 K08M4_RS00470 d1836acb20ad3822da4e6d0e46dfa0fe 275 ProSitePatterns PS01229 Hypothetical cof family signature 2. 222 244 - T 05-07-2017 K08M4_RS00470 d1836acb20ad3822da4e6d0e46dfa0fe 275 Gene3D G3DSA:3.40.50.1000 187 275 1.5E-54 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS00470 d1836acb20ad3822da4e6d0e46dfa0fe 275 Gene3D G3DSA:3.40.50.1000 7 80 1.5E-54 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS00470 d1836acb20ad3822da4e6d0e46dfa0fe 275 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 12 270 2.0E-60 T 05-07-2017 IPR000150 Cof protein GO:0016787 K08M4_RS00470 d1836acb20ad3822da4e6d0e46dfa0fe 275 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 12 241 2.3E-30 T 05-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 K08M4_RS00470 d1836acb20ad3822da4e6d0e46dfa0fe 275 Gene3D G3DSA:3.30.1240.10 90 186 5.4E-25 T 05-07-2017 K08M4_RS00470 d1836acb20ad3822da4e6d0e46dfa0fe 275 SUPERFAMILY SSF56784 7 274 1.07E-67 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS00470 d1836acb20ad3822da4e6d0e46dfa0fe 275 ProSitePatterns PS01228 Hypothetical cof family signature 1. 12 23 - T 05-07-2017 IPR000150 Cof protein GO:0016787 K08M4_RS00470 d1836acb20ad3822da4e6d0e46dfa0fe 275 Pfam PF08282 haloacid dehalogenase-like hydrolase 13 270 4.2E-65 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS03620 7d3ac492196fbed4a2e80e43dc66c6ae 156 Gene3D G3DSA:3.40.1280.10 2 155 4.9E-55 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal K08M4_RS03620 7d3ac492196fbed4a2e80e43dc66c6ae 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 27.669 T 05-07-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS03620 7d3ac492196fbed4a2e80e43dc66c6ae 156 PIRSF PIRSF004505 1 155 1.7E-43 T 05-07-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS03620 7d3ac492196fbed4a2e80e43dc66c6ae 156 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 156 2.7E-78 T 05-07-2017 IPR016051 Ribosomal RNA large subunit methyltransferase H GO:0005737|GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS03620 7d3ac492196fbed4a2e80e43dc66c6ae 156 Pfam PF02590 Predicted SPOUT methyltransferase 1 154 9.2E-49 T 05-07-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS03620 7d3ac492196fbed4a2e80e43dc66c6ae 156 SUPERFAMILY SSF75217 1 154 1.83E-50 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases K08M4_RS16735 2eae19e1a9a7623883ca8665c76536a9 294 Gene3D G3DSA:1.10.287.70 1 77 2.2E-16 T 05-07-2017 K08M4_RS16735 2eae19e1a9a7623883ca8665c76536a9 294 SUPERFAMILY SSF81452 4 294 9.29E-76 T 05-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16735 2eae19e1a9a7623883ca8665c76536a9 294 Gene3D G3DSA:1.20.120.80 81 293 3.5E-60 T 05-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS16735 2eae19e1a9a7623883ca8665c76536a9 294 Pfam PF00510 Cytochrome c oxidase subunit III 8 293 2.1E-46 T 05-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS17440 94d64620fae46c722879631dc728cc64 756 SMART SM00382 494 683 1.5E-5 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS17440 94d64620fae46c722879631dc728cc64 756 Pfam PF00664 ABC transporter transmembrane region 156 420 1.3E-16 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS17440 94d64620fae46c722879631dc728cc64 756 Pfam PF00005 ABC transporter 485 637 1.0E-14 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS17440 94d64620fae46c722879631dc728cc64 756 Gene3D G3DSA:1.20.1560.10 155 447 4.4E-36 T 05-07-2017 K08M4_RS17440 94d64620fae46c722879631dc728cc64 756 Gene3D G3DSA:3.40.50.300 468 716 9.3E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17440 94d64620fae46c722879631dc728cc64 756 SUPERFAMILY SSF90123 140 451 4.97E-40 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS17440 94d64620fae46c722879631dc728cc64 756 SUPERFAMILY SSF52540 457 691 8.62E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05055 271afea91dcb726128a887810b7e6828 213 PRINTS PR00988 Uridine kinase signature 178 191 1.1E-35 T 05-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 K08M4_RS05055 271afea91dcb726128a887810b7e6828 213 PRINTS PR00988 Uridine kinase signature 142 152 1.1E-35 T 05-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 K08M4_RS05055 271afea91dcb726128a887810b7e6828 213 PRINTS PR00988 Uridine kinase signature 156 167 1.1E-35 T 05-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 K08M4_RS05055 271afea91dcb726128a887810b7e6828 213 PRINTS PR00988 Uridine kinase signature 86 101 1.1E-35 T 05-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 K08M4_RS05055 271afea91dcb726128a887810b7e6828 213 PRINTS PR00988 Uridine kinase signature 41 52 1.1E-35 T 05-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 K08M4_RS05055 271afea91dcb726128a887810b7e6828 213 PRINTS PR00988 Uridine kinase signature 7 24 1.1E-35 T 05-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 K08M4_RS05055 271afea91dcb726128a887810b7e6828 213 TIGRFAM TIGR00235 udk: uridine kinase 3 211 2.3E-89 T 05-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 K08M4_RS05055 271afea91dcb726128a887810b7e6828 213 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 9 198 4.5E-41 T 05-07-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 K08M4_RS05055 271afea91dcb726128a887810b7e6828 213 Hamap MF_00551 Uridine kinase [udk]. 4 212 38.993 T 05-07-2017 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 K08M4_RS05055 271afea91dcb726128a887810b7e6828 213 Gene3D G3DSA:3.40.50.300 3 204 1.3E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05055 271afea91dcb726128a887810b7e6828 213 SUPERFAMILY SSF52540 6 204 2.76E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16745 c44c2879b2a775baeaf8f8435dbe02e9 308 Pfam PF02104 SURF1 family 67 284 4.3E-16 T 05-07-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 K08M4_RS11250 c6b64a0b143881f4a26a9ada91654df6 249 Pfam PF00849 RNA pseudouridylate synthase 11 170 1.3E-30 T 05-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS11250 c6b64a0b143881f4a26a9ada91654df6 249 SUPERFAMILY SSF55120 2 242 5.6E-63 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS11250 c6b64a0b143881f4a26a9ada91654df6 249 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 50 64 - T 05-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS13200 95cda9051a3366d78b64a757f17e8bd9 185 Pfam PF00436 Single-strand binding protein family 6 106 2.6E-43 T 05-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 K08M4_RS13200 95cda9051a3366d78b64a757f17e8bd9 185 Hamap MF_00984 Single-stranded DNA-binding protein. 6 118 39.357 T 05-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 K08M4_RS13200 95cda9051a3366d78b64a757f17e8bd9 185 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 185 1.0E-62 T 05-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 K08M4_RS13200 95cda9051a3366d78b64a757f17e8bd9 185 SUPERFAMILY SSF50249 4 185 2.91E-64 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS13200 95cda9051a3366d78b64a757f17e8bd9 185 PIRSF PIRSF002070 2 181 1.3E-36 T 05-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 K08M4_RS13200 95cda9051a3366d78b64a757f17e8bd9 185 Gene3D G3DSA:2.40.50.140 4 117 4.0E-55 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS13200 95cda9051a3366d78b64a757f17e8bd9 185 Gene3D G3DSA:2.40.50.140 154 185 4.0E-55 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS15700 8d7a1849f4f57e2de8983eca602eff9d 483 Gene3D G3DSA:2.40.180.10 3 356 8.1E-178 T 05-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 K08M4_RS15700 8d7a1849f4f57e2de8983eca602eff9d 483 ProSitePatterns PS00438 Catalase proximal active site signature. 42 58 - T 05-07-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 K08M4_RS15700 8d7a1849f4f57e2de8983eca602eff9d 483 PRINTS PR00067 Catalase signature 103 120 3.6E-71 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 K08M4_RS15700 8d7a1849f4f57e2de8983eca602eff9d 483 PRINTS PR00067 Catalase signature 19 42 3.6E-71 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 K08M4_RS15700 8d7a1849f4f57e2de8983eca602eff9d 483 PRINTS PR00067 Catalase signature 82 100 3.6E-71 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 K08M4_RS15700 8d7a1849f4f57e2de8983eca602eff9d 483 PRINTS PR00067 Catalase signature 122 140 3.6E-71 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 K08M4_RS15700 8d7a1849f4f57e2de8983eca602eff9d 483 PRINTS PR00067 Catalase signature 287 314 3.6E-71 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 K08M4_RS15700 8d7a1849f4f57e2de8983eca602eff9d 483 PRINTS PR00067 Catalase signature 319 345 3.6E-71 T 05-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 K08M4_RS15700 8d7a1849f4f57e2de8983eca602eff9d 483 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 332 340 - T 05-07-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 K08M4_RS15700 8d7a1849f4f57e2de8983eca602eff9d 483 SUPERFAMILY SSF56634 4 481 1.31E-215 T 05-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 K08M4_RS15700 8d7a1849f4f57e2de8983eca602eff9d 483 Pfam PF06628 Catalase-related immune-responsive 413 473 5.3E-21 T 05-07-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 K08M4_RS15700 8d7a1849f4f57e2de8983eca602eff9d 483 Pfam PF00199 Catalase 6 386 6.4E-190 T 05-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 K08M4_RS15700 8d7a1849f4f57e2de8983eca602eff9d 483 SMART SM01060 6 390 1.9E-286 T 05-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 K08M4_RS15700 8d7a1849f4f57e2de8983eca602eff9d 483 PIRSF PIRSF038928 1 480 1.6E-221 T 05-07-2017 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 K08M4_RS04550 20fc4728a772d34e25cb28a9f21ca93d 264 PIRSF PIRSF001430 1 254 1.5E-75 T 05-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS04550 20fc4728a772d34e25cb28a9f21ca93d 264 Gene3D G3DSA:3.30.70.580 2 104 1.9E-37 T 05-07-2017 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS04550 20fc4728a772d34e25cb28a9f21ca93d 264 Pfam PF01416 tRNA pseudouridine synthase 144 244 1.6E-29 T 05-07-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS04550 20fc4728a772d34e25cb28a9f21ca93d 264 Pfam PF01416 tRNA pseudouridine synthase 8 103 5.7E-11 T 05-07-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS04550 20fc4728a772d34e25cb28a9f21ca93d 264 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 238 5.2E-75 T 05-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS04550 20fc4728a772d34e25cb28a9f21ca93d 264 SUPERFAMILY SSF55120 1 256 5.75E-93 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS04550 20fc4728a772d34e25cb28a9f21ca93d 264 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 243 34.309 T 05-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS04550 20fc4728a772d34e25cb28a9f21ca93d 264 Gene3D G3DSA:3.30.70.660 106 241 3.7E-45 T 05-07-2017 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS19715 328854700b33fcb3f4e853f76e51a238 219 SUPERFAMILY SSF81324 119 211 5.23E-17 T 05-07-2017 K08M4_RS19715 328854700b33fcb3f4e853f76e51a238 219 Gene3D G3DSA:1.10.287.70 116 209 2.1E-15 T 05-07-2017 K08M4_RS19715 328854700b33fcb3f4e853f76e51a238 219 Pfam PF07885 Ion channel 126 210 1.5E-15 T 05-07-2017 IPR013099 Potassium channel domain K08M4_RS12845 adcf55b996afd4668f4ae51a809f98d6 422 SUPERFAMILY SSF53383 1 421 1.02E-125 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS12845 adcf55b996afd4668f4ae51a809f98d6 422 Gene3D G3DSA:3.40.640.10 2 285 1.2E-117 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS12845 adcf55b996afd4668f4ae51a809f98d6 422 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 420 1.2E-139 T 05-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 K08M4_RS12845 adcf55b996afd4668f4ae51a809f98d6 422 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 3 420 4.5E-199 T 05-07-2017 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 K08M4_RS12845 adcf55b996afd4668f4ae51a809f98d6 422 Gene3D G3DSA:3.90.1150.10 287 421 3.0E-49 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS12845 adcf55b996afd4668f4ae51a809f98d6 422 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 05-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 K08M4_RS12845 adcf55b996afd4668f4ae51a809f98d6 422 PIRSF PIRSF001434 1 422 7.1E-127 T 05-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 K08M4_RS05540 ce5d1082ca98e7b329705a68e3ab2e36 378 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 378 1.1E-163 T 05-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 K08M4_RS05540 ce5d1082ca98e7b329705a68e3ab2e36 378 PIRSF PIRSF000267 2 376 1.5E-121 T 05-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 K08M4_RS05540 ce5d1082ca98e7b329705a68e3ab2e36 378 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 361 2.7E-105 T 05-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 K08M4_RS20470 0a6ee16f39318f449bfe55ad8f7371a0 352 SUPERFAMILY SSF46689 302 351 4.93E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20470 0a6ee16f39318f449bfe55ad8f7371a0 352 Gene3D G3DSA:1.10.10.60 302 351 1.8E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20470 0a6ee16f39318f449bfe55ad8f7371a0 352 Pfam PF12833 Helix-turn-helix domain 272 350 8.3E-19 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS20470 0a6ee16f39318f449bfe55ad8f7371a0 352 SMART SM00342 266 349 2.6E-16 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS10660 e050782995f49b7b7027b6e769b684f5 404 Gene3D G3DSA:3.30.420.40 222 374 1.6E-46 T 05-07-2017 K08M4_RS10660 e050782995f49b7b7027b6e769b684f5 404 Pfam PF00480 ROK family 86 390 1.6E-72 T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 K08M4_RS10660 e050782995f49b7b7027b6e769b684f5 404 SUPERFAMILY SSF53067 85 391 9.72E-55 T 05-07-2017 K08M4_RS10660 e050782995f49b7b7027b6e769b684f5 404 Gene3D G3DSA:1.10.10.10 11 78 4.3E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS10660 e050782995f49b7b7027b6e769b684f5 404 SUPERFAMILY SSF46785 11 75 7.12E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS10660 e050782995f49b7b7027b6e769b684f5 404 ProSitePatterns PS01125 ROK family signature. 217 244 - T 05-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 K08M4_RS10660 e050782995f49b7b7027b6e769b684f5 404 Gene3D G3DSA:3.30.420.40 83 221 2.1E-33 T 05-07-2017 K08M4_RS02225 fdc29e6e49c3b77bb8b74f7667fd40a8 270 Gene3D G3DSA:3.40.1010.10 2 110 4.0E-30 T 05-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS02225 fdc29e6e49c3b77bb8b74f7667fd40a8 270 Gene3D G3DSA:3.30.950.10 111 229 5.3E-35 T 05-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS02225 fdc29e6e49c3b77bb8b74f7667fd40a8 270 SUPERFAMILY SSF53790 2 230 3.53E-63 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS02225 fdc29e6e49c3b77bb8b74f7667fd40a8 270 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 05-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 K08M4_RS02225 fdc29e6e49c3b77bb8b74f7667fd40a8 270 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 207 7.4E-44 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS02225 fdc29e6e49c3b77bb8b74f7667fd40a8 270 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 248 2.7E-97 T 05-07-2017 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 K08M4_RS12115 7a69f96839504d92cc2dc53bf4ea0fc8 246 Gene3D G3DSA:3.60.140.10 2 245 1.1E-91 T 05-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase K08M4_RS12115 7a69f96839504d92cc2dc53bf4ea0fc8 246 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 19 244 7.8E-71 T 05-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase K08M4_RS12115 7a69f96839504d92cc2dc53bf4ea0fc8 246 SUPERFAMILY SSF64438 3 246 9.34E-82 T 05-07-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic K08M4_RS12115 7a69f96839504d92cc2dc53bf4ea0fc8 246 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 29 245 3.5E-60 T 05-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase K08M4_RS12405 452edfae31bb9e8157952e30773226ad 427 Pfam PF14821 Threonine synthase N terminus 8 78 1.4E-8 T 05-07-2017 IPR029144 Threonine synthase, N-terminal K08M4_RS12405 452edfae31bb9e8157952e30773226ad 427 Gene3D G3DSA:3.40.50.1100 104 192 8.5E-13 T 05-07-2017 K08M4_RS12405 452edfae31bb9e8157952e30773226ad 427 Gene3D G3DSA:3.90.1380.10 1 82 7.8E-18 T 05-07-2017 IPR029144 Threonine synthase, N-terminal K08M4_RS12405 452edfae31bb9e8157952e30773226ad 427 Gene3D G3DSA:3.40.50.1100 324 398 1.3E-14 T 05-07-2017 K08M4_RS12405 452edfae31bb9e8157952e30773226ad 427 Gene3D G3DSA:3.40.50.1100 193 314 4.9E-53 T 05-07-2017 K08M4_RS12405 452edfae31bb9e8157952e30773226ad 427 SUPERFAMILY SSF53686 1 424 9.3E-130 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme K08M4_RS12405 452edfae31bb9e8157952e30773226ad 427 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 95 109 - T 05-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 K08M4_RS12405 452edfae31bb9e8157952e30773226ad 427 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 90 365 5.8E-24 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme K08M4_RS12405 452edfae31bb9e8157952e30773226ad 427 TIGRFAM TIGR00260 thrC: threonine synthase 52 391 3.6E-112 T 05-07-2017 IPR004450 Threonine synthase-like K08M4_RS12730 0948115d5b3826d71c4c7ad6707e13b9 436 Pfam PF02321 Outer membrane efflux protein 25 209 2.3E-26 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS12730 0948115d5b3826d71c4c7ad6707e13b9 436 Pfam PF02321 Outer membrane efflux protein 235 417 5.1E-30 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS12730 0948115d5b3826d71c4c7ad6707e13b9 436 SUPERFAMILY SSF56954 1 423 4.32E-85 T 05-07-2017 K08M4_RS12730 0948115d5b3826d71c4c7ad6707e13b9 436 Gene3D G3DSA:1.20.1600.10 23 424 7.2E-77 T 05-07-2017 K08M4_RS12730 0948115d5b3826d71c4c7ad6707e13b9 436 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 22 431 7.4E-106 T 05-07-2017 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 K08M4_RS16100 1c9a612577f2522229a61e1df8ee7422 594 SUPERFAMILY SSF82866 392 588 5.89E-40 T 05-07-2017 K08M4_RS16100 1c9a612577f2522229a61e1df8ee7422 594 Pfam PF07549 SecD/SecF GG Motif 116 134 1.2E-4 T 05-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site K08M4_RS16100 1c9a612577f2522229a61e1df8ee7422 594 Pfam PF13721 SecD export protein N-terminal TM region 10 92 5.1E-8 T 05-07-2017 IPR027398 SecD export protein N-terminal TM domain K08M4_RS16100 1c9a612577f2522229a61e1df8ee7422 594 Gene3D G3DSA:1.20.1640.10 426 585 3.4E-25 T 05-07-2017 K08M4_RS16100 1c9a612577f2522229a61e1df8ee7422 594 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 9 594 39.102 T 05-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 K08M4_RS16100 1c9a612577f2522229a61e1df8ee7422 594 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 119 581 5.4E-123 T 05-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 K08M4_RS16100 1c9a612577f2522229a61e1df8ee7422 594 Pfam PF02355 Protein export membrane protein 415 581 1.8E-19 T 05-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial K08M4_RS16100 1c9a612577f2522229a61e1df8ee7422 594 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 333 574 4.0E-74 T 05-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial K08M4_RS19685 3d18ae95f4f42ee4196e3e6a589a5973 316 Pfam PF01032 FecCD transport family 14 312 2.1E-57 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 K08M4_RS19685 3d18ae95f4f42ee4196e3e6a589a5973 316 Gene3D G3DSA:1.10.3470.10 20 314 8.5E-60 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS19685 3d18ae95f4f42ee4196e3e6a589a5973 316 SUPERFAMILY SSF81345 9 312 1.31E-57 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 PRINTS PR00046 Major sigma-70 factor signature 222 233 1.2E-11 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 PRINTS PR00046 Major sigma-70 factor signature 46 59 1.2E-11 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 PRINTS PR00046 Major sigma-70 factor signature 190 202 1.2E-11 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 PRINTS PR00046 Major sigma-70 factor signature 207 222 1.2E-11 T 05-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 SUPERFAMILY SSF88659 162 239 6.35E-20 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 Pfam PF04545 Sigma-70, region 4 187 234 1.8E-17 T 05-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 Gene3D G3DSA:1.10.601.10 16 86 6.7E-16 T 05-07-2017 K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 Gene3D G3DSA:1.10.10.10 175 238 2.0E-13 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 Pfam PF04539 Sigma-70 region 3 100 171 2.5E-11 T 05-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 PIRSF PIRSF000770 3 243 1.1E-37 T 05-07-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 SUPERFAMILY SSF88946 6 91 7.33E-23 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 20 238 2.8E-83 T 05-07-2017 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. 5 240 62.846 T 05-07-2017 IPR028617 RNA polymerase sigma factor FliA GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 Gene3D G3DSA:1.10.10.10 91 138 9.1E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 237 2.0E-31 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 SUPERFAMILY SSF88659 92 157 6.1E-15 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04240 6fa804a20ffc3088c9619686860df5b7 244 Pfam PF04542 Sigma-70 region 2 19 91 3.2E-15 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS13985 0a89c59dbc11ad5471357365f53d9fc1 439 SUPERFAMILY SSF53756 116 402 2.67E-6 T 05-07-2017 K08M4_RS13985 0a89c59dbc11ad5471357365f53d9fc1 439 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 36 214 2.8E-60 T 05-07-2017 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 K08M4_RS17060 1f6d5b5096f1073d70b35e7ef784fa91 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 6.0E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS17060 1f6d5b5096f1073d70b35e7ef784fa91 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 6.0E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS17060 1f6d5b5096f1073d70b35e7ef784fa91 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 6.0E-6 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS17060 1f6d5b5096f1073d70b35e7ef784fa91 310 Gene3D G3DSA:1.10.10.10 12 87 1.1E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS17060 1f6d5b5096f1073d70b35e7ef784fa91 310 SUPERFAMILY SSF53850 95 304 1.23E-38 T 05-07-2017 K08M4_RS17060 1f6d5b5096f1073d70b35e7ef784fa91 310 Gene3D G3DSA:3.40.190.10 98 182 1.1E-20 T 05-07-2017 K08M4_RS17060 1f6d5b5096f1073d70b35e7ef784fa91 310 Gene3D G3DSA:3.40.190.10 183 264 1.9E-8 T 05-07-2017 K08M4_RS17060 1f6d5b5096f1073d70b35e7ef784fa91 310 SUPERFAMILY SSF46785 10 116 1.11E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS17060 1f6d5b5096f1073d70b35e7ef784fa91 310 Pfam PF03466 LysR substrate binding domain 94 301 3.8E-37 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS17060 1f6d5b5096f1073d70b35e7ef784fa91 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 69 6.0E-19 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS00190 9486395515fd91cf14037bd014bfedbc 596 Gene3D G3DSA:3.90.230.10 301 559 7.7E-57 T 05-07-2017 IPR000994 Peptidase M24, structural domain K08M4_RS00190 9486395515fd91cf14037bd014bfedbc 596 Pfam PF00557 Metallopeptidase family M24 309 523 1.8E-42 T 05-07-2017 IPR000994 Peptidase M24, structural domain K08M4_RS00190 9486395515fd91cf14037bd014bfedbc 596 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 138 3.1E-20 T 05-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 K08M4_RS00190 9486395515fd91cf14037bd014bfedbc 596 Gene3D G3DSA:3.40.350.10 5 134 6.8E-24 T 05-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal K08M4_RS00190 9486395515fd91cf14037bd014bfedbc 596 Pfam PF16189 Creatinase/Prolidase N-terminal domain 148 306 6.0E-32 T 05-07-2017 K08M4_RS00190 9486395515fd91cf14037bd014bfedbc 596 SUPERFAMILY SSF53092 6 130 9.07E-18 T 05-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal K08M4_RS00190 9486395515fd91cf14037bd014bfedbc 596 SUPERFAMILY SSF55920 303 559 2.09E-53 T 05-07-2017 IPR000994 Peptidase M24, structural domain K08M4_RS00190 9486395515fd91cf14037bd014bfedbc 596 Pfam PF16188 C-terminal region of peptidase_M24 534 593 5.8E-23 T 05-07-2017 IPR032416 Peptidase M24, C-terminal domain K08M4_RS06825 6c9e38dfd9a4545d63b64aa25b58ed54 496 Pfam PF12161 HsdM N-terminal domain 6 108 4.3E-9 T 05-07-2017 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain K08M4_RS06825 6c9e38dfd9a4545d63b64aa25b58ed54 496 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 256 262 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 K08M4_RS06825 6c9e38dfd9a4545d63b64aa25b58ed54 496 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 166 180 7.1E-16 T 05-07-2017 K08M4_RS06825 6c9e38dfd9a4545d63b64aa25b58ed54 496 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 142 158 7.1E-16 T 05-07-2017 K08M4_RS06825 6c9e38dfd9a4545d63b64aa25b58ed54 496 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 283 307 7.1E-16 T 05-07-2017 K08M4_RS06825 6c9e38dfd9a4545d63b64aa25b58ed54 496 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 253 265 7.1E-16 T 05-07-2017 K08M4_RS06825 6c9e38dfd9a4545d63b64aa25b58ed54 496 SUPERFAMILY SSF53335 4 484 2.61E-117 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS06825 6c9e38dfd9a4545d63b64aa25b58ed54 496 Pfam PF02384 N-6 DNA Methylase 120 443 3.3E-73 T 05-07-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 K08M4_RS06825 6c9e38dfd9a4545d63b64aa25b58ed54 496 Gene3D G3DSA:3.40.50.150 144 377 1.6E-36 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS19795 15538c2c9f16b5070ca377dadac4ba2d 302 SUPERFAMILY SSF53613 33 295 3.74E-83 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS19795 15538c2c9f16b5070ca377dadac4ba2d 302 Pfam PF08543 Phosphomethylpyrimidine kinase 44 292 1.3E-93 T 05-07-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 K08M4_RS19795 15538c2c9f16b5070ca377dadac4ba2d 302 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 37 294 4.1E-99 T 05-07-2017 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 K08M4_RS19795 15538c2c9f16b5070ca377dadac4ba2d 302 Gene3D G3DSA:3.40.1190.20 35 294 6.0E-102 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS08955 71d4204e1504fd71178600712ab3c3db 523 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 33 520 4.8E-174 T 05-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 K08M4_RS08955 71d4204e1504fd71178600712ab3c3db 523 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 73 520 5.1E-139 T 05-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 K08M4_RS08955 71d4204e1504fd71178600712ab3c3db 523 ProSitePatterns PS01303 BCCT family of transporters signature. 336 345 - T 05-07-2017 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 K08M4_RS11095 5eec41125435e0abbea0ce596b9b59ba 233 SMART SM00479 1 178 1.5E-47 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS11095 5eec41125435e0abbea0ce596b9b59ba 233 Pfam PF00929 Exonuclease 2 169 8.3E-37 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS11095 5eec41125435e0abbea0ce596b9b59ba 233 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 233 2.8E-99 T 05-07-2017 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS11095 5eec41125435e0abbea0ce596b9b59ba 233 SUPERFAMILY SSF53098 1 179 1.64E-52 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS11095 5eec41125435e0abbea0ce596b9b59ba 233 Gene3D G3DSA:3.30.420.10 1 180 3.9E-63 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS11095 5eec41125435e0abbea0ce596b9b59ba 233 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 2 216 1.7E-81 T 05-07-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS07985 4aef8474441a59e7542f44f4eb8781b1 470 SUPERFAMILY SSF48317 191 352 3.92E-10 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase K08M4_RS07985 4aef8474441a59e7542f44f4eb8781b1 470 Pfam PF01569 PAP2 superfamily 235 349 1.2E-12 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase K08M4_RS07985 4aef8474441a59e7542f44f4eb8781b1 470 ProSitePatterns PS00893 Nudix box signature. 58 79 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 K08M4_RS07985 4aef8474441a59e7542f44f4eb8781b1 470 Pfam PF00293 NUDIX domain 31 142 1.7E-10 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 K08M4_RS07985 4aef8474441a59e7542f44f4eb8781b1 470 SUPERFAMILY SSF55811 26 160 3.25E-18 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS07985 4aef8474441a59e7542f44f4eb8781b1 470 Gene3D G3DSA:1.20.144.10 170 350 2.5E-8 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase K08M4_RS07985 4aef8474441a59e7542f44f4eb8781b1 470 Gene3D G3DSA:3.90.79.10 27 143 1.9E-14 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS18925 5e949cdb899ed7b673458832836454e1 434 Pfam PF00294 pfkB family carbohydrate kinase 138 293 8.5E-12 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB K08M4_RS18925 5e949cdb899ed7b673458832836454e1 434 SUPERFAMILY SSF53613 338 417 8.18E-44 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS18925 5e949cdb899ed7b673458832836454e1 434 SUPERFAMILY SSF53613 34 305 8.18E-44 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS18925 5e949cdb899ed7b673458832836454e1 434 Gene3D G3DSA:3.30.1110.10 45 84 4.5E-7 T 05-07-2017 K08M4_RS18925 5e949cdb899ed7b673458832836454e1 434 Gene3D G3DSA:3.40.1190.20 337 433 9.3E-43 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS18925 5e949cdb899ed7b673458832836454e1 434 Gene3D G3DSA:3.40.1190.20 144 298 9.3E-43 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS00385 41cfe15e455f7537eec808c79fc6c559 393 SUPERFAMILY SSF48452 308 389 5.22E-9 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS00385 41cfe15e455f7537eec808c79fc6c559 393 SUPERFAMILY SSF48452 84 207 1.52E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS00385 41cfe15e455f7537eec808c79fc6c559 393 Pfam PF07219 HemY protein N-terminus 26 132 9.0E-28 T 05-07-2017 IPR010817 HemY, N-terminal K08M4_RS00385 41cfe15e455f7537eec808c79fc6c559 393 Gene3D G3DSA:1.25.40.10 314 389 3.2E-10 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS00385 41cfe15e455f7537eec808c79fc6c559 393 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 3 386 5.7E-107 T 05-07-2017 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 K08M4_RS01385 847d0082ee793839dc56c1bf371be877 598 Hamap MF_01412 Glutathione-regulated potassium-efflux system protein KefB [kefB]. 3 598 49.802 T 05-07-2017 IPR020884 Glutathione-regulated potassium-efflux system protein KefB GO:0005886|GO:0006813|GO:0015503 K08M4_RS01385 847d0082ee793839dc56c1bf371be877 598 Pfam PF00999 Sodium/hydrogen exchanger family 13 372 1.1E-64 T 05-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 K08M4_RS01385 847d0082ee793839dc56c1bf371be877 598 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 15 282 1.2E-80 T 05-07-2017 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 K08M4_RS01385 847d0082ee793839dc56c1bf371be877 598 SUPERFAMILY SSF51735 401 528 1.42E-28 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS01385 847d0082ee793839dc56c1bf371be877 598 Gene3D G3DSA:3.40.50.720 397 530 4.6E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS01385 847d0082ee793839dc56c1bf371be877 598 PRINTS PR00335 TrkA potassium uptake protein signature 458 468 2.9E-7 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 K08M4_RS01385 847d0082ee793839dc56c1bf371be877 598 PRINTS PR00335 TrkA potassium uptake protein signature 418 432 2.9E-7 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 K08M4_RS01385 847d0082ee793839dc56c1bf371be877 598 PRINTS PR00335 TrkA potassium uptake protein signature 447 457 2.9E-7 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 K08M4_RS01385 847d0082ee793839dc56c1bf371be877 598 PRINTS PR00335 TrkA potassium uptake protein signature 401 415 2.9E-7 T 05-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 K08M4_RS01385 847d0082ee793839dc56c1bf371be877 598 Pfam PF02254 TrkA-N domain 402 511 4.9E-21 T 05-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 K08M4_RS15950 ecfbb9e25cc502c20bfafc4d296446b5 443 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 05-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site K08M4_RS15950 ecfbb9e25cc502c20bfafc4d296446b5 443 SMART SM00490 260 341 1.9E-33 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS15950 ecfbb9e25cc502c20bfafc4d296446b5 443 SUPERFAMILY SSF52540 73 359 6.69E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15950 ecfbb9e25cc502c20bfafc4d296446b5 443 Pfam PF00271 Helicase conserved C-terminal domain 236 341 6.7E-30 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS15950 ecfbb9e25cc502c20bfafc4d296446b5 443 Gene3D G3DSA:3.40.50.300 214 369 3.9E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15950 ecfbb9e25cc502c20bfafc4d296446b5 443 Gene3D G3DSA:3.40.50.300 2 213 2.8E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15950 ecfbb9e25cc502c20bfafc4d296446b5 443 Pfam PF00270 DEAD/DEAH box helicase 25 196 3.0E-46 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS15950 ecfbb9e25cc502c20bfafc4d296446b5 443 SMART SM00487 20 223 3.1E-51 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS19115 09fe89798d931e23ce13e052a54e4301 354 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 201 300 5.7E-19 T 05-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain K08M4_RS19115 09fe89798d931e23ce13e052a54e4301 354 Gene3D G3DSA:2.40.50.100 221 255 4.5E-22 T 05-07-2017 K08M4_RS19115 09fe89798d931e23ce13e052a54e4301 354 Gene3D G3DSA:2.40.50.100 58 90 4.5E-22 T 05-07-2017 K08M4_RS19115 09fe89798d931e23ce13e052a54e4301 354 Pfam PF13533 Biotin-lipoyl like 58 104 6.9E-15 T 05-07-2017 K08M4_RS19115 09fe89798d931e23ce13e052a54e4301 354 SUPERFAMILY SSF111369 57 141 4.71E-13 T 05-07-2017 K08M4_RS19115 09fe89798d931e23ce13e052a54e4301 354 SUPERFAMILY SSF111369 129 184 2.75E-6 T 05-07-2017 K08M4_RS19115 09fe89798d931e23ce13e052a54e4301 354 SUPERFAMILY SSF111369 195 298 1.26E-14 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 PIRSF PIRSF000350 1 471 1.2E-58 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 Gene3D G3DSA:3.50.50.60 274 338 1.2E-47 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 Gene3D G3DSA:3.50.50.60 5 146 1.2E-47 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 355 463 1.1E-16 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 416 431 2.8E-39 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 348 369 2.8E-39 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 2.8E-39 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 2.8E-39 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 311 318 2.8E-39 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 2.8E-39 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.8E-39 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 2.8E-39 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 438 458 2.8E-39 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 SUPERFAMILY SSF51905 1 56 1.61E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 SUPERFAMILY SSF51905 103 191 1.61E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 SUPERFAMILY SSF51905 225 370 1.61E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 SUPERFAMILY SSF55424 354 472 2.75E-24 T 05-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.8E-20 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 1.8E-20 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 296 318 1.8E-20 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 1.8E-20 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 1.8E-20 T 05-07-2017 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 331 1.2E-40 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 Gene3D G3DSA:3.30.390.30 354 467 4.8E-25 T 05-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 K08M4_RS01230 602e085fc9189241016496f45eb2f272 488 Gene3D G3DSA:3.50.50.60 149 273 4.0E-20 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS10980 8784a3c3d528f43ecbf8ac2daa61aee6 115 SUPERFAMILY SSF52833 2 114 7.36E-36 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS10980 8784a3c3d528f43ecbf8ac2daa61aee6 115 Gene3D G3DSA:3.40.30.10 2 114 2.9E-44 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS10980 8784a3c3d528f43ecbf8ac2daa61aee6 115 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 112 1.6E-33 T 05-07-2017 IPR006504 Transcriptional regulator Spx/MgsR K08M4_RS10980 8784a3c3d528f43ecbf8ac2daa61aee6 115 Pfam PF03960 ArsC family 7 113 1.5E-19 T 05-07-2017 IPR006660 Arsenate reductase-like K08M4_RS08210 1b024a4bca2b5e30fc2d950a0ae2c772 165 Gene3D G3DSA:3.30.70.560 3 150 6.6E-39 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS08210 1b024a4bca2b5e30fc2d950a0ae2c772 165 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 129 7.5E-26 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS08210 1b024a4bca2b5e30fc2d950a0ae2c772 165 SUPERFAMILY SSF55083 1 151 2.62E-40 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS08210 1b024a4bca2b5e30fc2d950a0ae2c772 165 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 129 4.7E-27 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS16115 4f58f269bb659cd985ba05384b6833ec 599 SUPERFAMILY SSF50182 372 436 4.25E-12 T 05-07-2017 IPR010920 LSM domain K08M4_RS16115 4f58f269bb659cd985ba05384b6833ec 599 SUPERFAMILY SSF82861 291 369 3.01E-8 T 05-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 K08M4_RS16115 4f58f269bb659cd985ba05384b6833ec 599 Gene3D G3DSA:2.30.30.60 388 435 6.2E-14 T 05-07-2017 K08M4_RS16115 4f58f269bb659cd985ba05384b6833ec 599 Pfam PF00924 Mechanosensitive ion channel 334 529 3.8E-33 T 05-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 K08M4_RS00240 5d8bc4678b3517df76ea3fd9274e8a9f 585 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 51 577 9.1E-136 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 K08M4_RS00240 5d8bc4678b3517df76ea3fd9274e8a9f 585 Pfam PF01019 Gamma-glutamyltranspeptidase 65 580 3.0E-159 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 K08M4_RS00240 5d8bc4678b3517df76ea3fd9274e8a9f 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 72 97 1.3E-64 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 K08M4_RS00240 5d8bc4678b3517df76ea3fd9274e8a9f 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 406 424 1.3E-64 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 K08M4_RS00240 5d8bc4678b3517df76ea3fd9274e8a9f 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 147 165 1.3E-64 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 K08M4_RS00240 5d8bc4678b3517df76ea3fd9274e8a9f 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 165 184 1.3E-64 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 K08M4_RS00240 5d8bc4678b3517df76ea3fd9274e8a9f 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 297 316 1.3E-64 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 K08M4_RS00240 5d8bc4678b3517df76ea3fd9274e8a9f 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 428 446 1.3E-64 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 K08M4_RS00240 5d8bc4678b3517df76ea3fd9274e8a9f 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 464 479 1.3E-64 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 K08M4_RS00240 5d8bc4678b3517df76ea3fd9274e8a9f 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 488 505 1.3E-64 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 K08M4_RS00240 5d8bc4678b3517df76ea3fd9274e8a9f 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 267 283 1.3E-64 T 05-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 K08M4_RS00240 5d8bc4678b3517df76ea3fd9274e8a9f 585 SUPERFAMILY SSF56235 42 584 3.09E-171 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS10350 594e7c23e7ab2b4cc7e222ce30714f2d 447 SUPERFAMILY SSF109604 25 173 4.89E-77 T 05-07-2017 K08M4_RS10350 594e7c23e7ab2b4cc7e222ce30714f2d 447 SUPERFAMILY SSF109604 238 444 4.89E-77 T 05-07-2017 K08M4_RS10350 594e7c23e7ab2b4cc7e222ce30714f2d 447 Gene3D G3DSA:1.10.3210.10 11 256 2.0E-68 T 05-07-2017 IPR006674 HD domain K08M4_RS10350 594e7c23e7ab2b4cc7e222ce30714f2d 447 Gene3D G3DSA:1.10.3550.10 360 438 8.1E-5 T 05-07-2017 IPR027432 Deoxyguanosinetriphosphate triphosphohydrolase, C-terminal domain K08M4_RS10350 594e7c23e7ab2b4cc7e222ce30714f2d 447 SMART SM00471 64 270 5.0E-9 T 05-07-2017 IPR003607 HD/PDEase domain K08M4_RS10350 594e7c23e7ab2b4cc7e222ce30714f2d 447 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 5 441 34.401 T 05-07-2017 IPR023023 Deoxyguanosinetriphosphate triphosphohydrolase, type 2 K08M4_RS10350 594e7c23e7ab2b4cc7e222ce30714f2d 447 Gene3D G3DSA:1.10.3410.10 257 359 1.0E-22 T 05-07-2017 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain K08M4_RS10350 594e7c23e7ab2b4cc7e222ce30714f2d 447 Pfam PF01966 HD domain 68 150 1.8E-7 T 05-07-2017 IPR006674 HD domain K08M4_RS10350 594e7c23e7ab2b4cc7e222ce30714f2d 447 Pfam PF13286 Phosphohydrolase-associated domain 348 439 9.2E-26 T 05-07-2017 IPR026875 Phosphohydrolase-associated domain K08M4_RS10350 594e7c23e7ab2b4cc7e222ce30714f2d 447 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 30 442 7.8E-124 T 05-07-2017 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 K08M4_RS03650 bf3deaa85f09c012e4b2132834797335 504 Pfam PF00795 Carbon-nitrogen hydrolase 233 469 2.8E-35 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 K08M4_RS03650 bf3deaa85f09c012e4b2132834797335 504 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 8 490 23.044 T 05-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 K08M4_RS03650 bf3deaa85f09c012e4b2132834797335 504 SUPERFAMILY SSF56317 214 485 5.62E-38 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 K08M4_RS03650 bf3deaa85f09c012e4b2132834797335 504 Gene3D G3DSA:3.60.110.10 215 471 9.3E-21 T 05-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 K08M4_RS03650 bf3deaa85f09c012e4b2132834797335 504 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 61 452 2.5E-95 T 05-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 K08M4_RS06790 5ab1dd5506405b908960c48553dc39f6 275 Pfam PF13391 HNH endonuclease 173 225 5.3E-9 T 05-07-2017 IPR003615 HNH nuclease K08M4_RS00255 d9ebc3dfc3c696afd5753d0993348bd8 302 SUPERFAMILY SSF103481 207 291 1.96E-7 T 05-07-2017 K08M4_RS00255 d9ebc3dfc3c696afd5753d0993348bd8 302 SUPERFAMILY SSF103481 49 146 9.42E-13 T 05-07-2017 K08M4_RS00255 d9ebc3dfc3c696afd5753d0993348bd8 302 Pfam PF00892 EamA-like transporter family 12 145 7.6E-16 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS00255 d9ebc3dfc3c696afd5753d0993348bd8 302 TIGRFAM TIGR00688 rarD: protein RarD 11 264 1.5E-88 T 05-07-2017 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 K08M4_RS04435 8ef596c270a3a3f3929ac553b2a90b3e 270 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 268 8.9E-109 T 05-07-2017 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 K08M4_RS04435 8ef596c270a3a3f3929ac553b2a90b3e 270 Gene3D G3DSA:3.40.50.300 1 248 2.8E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04435 8ef596c270a3a3f3929ac553b2a90b3e 270 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 217 7.9E-27 T 05-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain K08M4_RS04435 8ef596c270a3a3f3929ac553b2a90b3e 270 SUPERFAMILY SSF52540 1 268 7.96E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04435 8ef596c270a3a3f3929ac553b2a90b3e 270 PIRSF PIRSF003092 1 270 1.0E-94 T 05-07-2017 IPR025501 ATP binding protein MinD K08M4_RS17110 630e71a772b94ea07537b0ec8e07d2e6 343 SUPERFAMILY SSF50129 3 175 1.16E-50 T 05-07-2017 IPR011032 GroES-like K08M4_RS17110 630e71a772b94ea07537b0ec8e07d2e6 343 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 05-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 K08M4_RS17110 630e71a772b94ea07537b0ec8e07d2e6 343 Gene3D G3DSA:3.90.180.10 1 174 2.3E-49 T 05-07-2017 IPR011032 GroES-like K08M4_RS17110 630e71a772b94ea07537b0ec8e07d2e6 343 Pfam PF00107 Zinc-binding dehydrogenase 176 303 1.1E-26 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 K08M4_RS17110 630e71a772b94ea07537b0ec8e07d2e6 343 SMART SM00829 14 340 5.8E-4 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 K08M4_RS17110 630e71a772b94ea07537b0ec8e07d2e6 343 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 3 342 60.061 T 05-07-2017 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 K08M4_RS17110 630e71a772b94ea07537b0ec8e07d2e6 343 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 5 342 1.7E-177 T 05-07-2017 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 K08M4_RS17110 630e71a772b94ea07537b0ec8e07d2e6 343 SUPERFAMILY SSF51735 143 307 5.3E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS17110 630e71a772b94ea07537b0ec8e07d2e6 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 136 1.6E-30 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 K08M4_RS17110 630e71a772b94ea07537b0ec8e07d2e6 343 Gene3D G3DSA:3.40.50.720 175 289 4.0E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS18600 16e0526dd3dc32f482b01e87a8cc888e 255 Gene3D G3DSA:2.40.100.10 103 244 3.0E-41 T 05-07-2017 IPR029000 Cyclophilin-like domain K08M4_RS18600 16e0526dd3dc32f482b01e87a8cc888e 255 SMART SM00796 8 224 1.1E-55 T 05-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D K08M4_RS18600 16e0526dd3dc32f482b01e87a8cc888e 255 SUPERFAMILY SSF50891 104 240 4.55E-35 T 05-07-2017 IPR029000 Cyclophilin-like domain K08M4_RS18600 16e0526dd3dc32f482b01e87a8cc888e 255 SUPERFAMILY SSF160467 10 107 3.4E-9 T 05-07-2017 K08M4_RS18600 16e0526dd3dc32f482b01e87a8cc888e 255 Pfam PF02682 Allophanate hydrolase subunit 1 9 210 8.6E-52 T 05-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D K08M4_RS18600 16e0526dd3dc32f482b01e87a8cc888e 255 Gene3D G3DSA:3.30.1360.40 11 88 2.6E-7 T 05-07-2017 IPR024946 Arginine repressor C-terminal-like domain K08M4_RS18250 d8b414c5aca5958d5ebde7943b035c66 206 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 127 204 1.8E-18 T 05-07-2017 IPR006260 TonB, C-terminal GO:0006810 K08M4_RS18250 d8b414c5aca5958d5ebde7943b035c66 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 161 178 8.0E-15 T 05-07-2017 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 K08M4_RS18250 d8b414c5aca5958d5ebde7943b035c66 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 64 74 8.0E-15 T 05-07-2017 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 K08M4_RS18250 d8b414c5aca5958d5ebde7943b035c66 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 121 142 8.0E-15 T 05-07-2017 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 K08M4_RS18250 d8b414c5aca5958d5ebde7943b035c66 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 142 160 8.0E-15 T 05-07-2017 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 K08M4_RS18250 d8b414c5aca5958d5ebde7943b035c66 206 SUPERFAMILY SSF74653 118 196 2.09E-25 T 05-07-2017 K08M4_RS18250 d8b414c5aca5958d5ebde7943b035c66 206 Gene3D G3DSA:3.30.1150.10 117 204 7.4E-12 T 05-07-2017 K08M4_RS18250 d8b414c5aca5958d5ebde7943b035c66 206 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 126 204 6.0E-21 T 05-07-2017 IPR006260 TonB, C-terminal GO:0006810 K08M4_RS18095 d8b414c5aca5958d5ebde7943b035c66 206 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 127 204 1.8E-18 T 05-07-2017 IPR006260 TonB, C-terminal GO:0006810 K08M4_RS18095 d8b414c5aca5958d5ebde7943b035c66 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 161 178 8.0E-15 T 05-07-2017 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 K08M4_RS18095 d8b414c5aca5958d5ebde7943b035c66 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 64 74 8.0E-15 T 05-07-2017 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 K08M4_RS18095 d8b414c5aca5958d5ebde7943b035c66 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 121 142 8.0E-15 T 05-07-2017 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 K08M4_RS18095 d8b414c5aca5958d5ebde7943b035c66 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 142 160 8.0E-15 T 05-07-2017 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 K08M4_RS18095 d8b414c5aca5958d5ebde7943b035c66 206 SUPERFAMILY SSF74653 118 196 2.09E-25 T 05-07-2017 K08M4_RS18095 d8b414c5aca5958d5ebde7943b035c66 206 Gene3D G3DSA:3.30.1150.10 117 204 7.4E-12 T 05-07-2017 K08M4_RS18095 d8b414c5aca5958d5ebde7943b035c66 206 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 126 204 6.0E-21 T 05-07-2017 IPR006260 TonB, C-terminal GO:0006810 K08M4_RS17500 3819ddbe17bf141be94d4fcc5c806577 659 Gene3D G3DSA:2.60.40.60 449 550 2.8E-4 T 05-07-2017 IPR002126 Cadherin GO:0005509|GO:0007156|GO:0016020 K08M4_RS17500 3819ddbe17bf141be94d4fcc5c806577 659 SUPERFAMILY SSF49313 571 650 2.67E-6 T 05-07-2017 IPR015919 Cadherin-like GO:0005509|GO:0016020 K08M4_RS17500 3819ddbe17bf141be94d4fcc5c806577 659 SMART SM00736 555 652 0.03 T 05-07-2017 IPR006644 Dystroglycan-type cadherin-like GO:0016020 K08M4_RS17500 3819ddbe17bf141be94d4fcc5c806577 659 SMART SM00736 452 550 0.07 T 05-07-2017 IPR006644 Dystroglycan-type cadherin-like GO:0016020 K08M4_RS17500 3819ddbe17bf141be94d4fcc5c806577 659 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 567 655 1.9E-14 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS17500 3819ddbe17bf141be94d4fcc5c806577 659 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 180 257 6.5E-12 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS17500 3819ddbe17bf141be94d4fcc5c806577 659 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 268 363 1.3E-28 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS17500 3819ddbe17bf141be94d4fcc5c806577 659 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 468 561 4.8E-13 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS17500 3819ddbe17bf141be94d4fcc5c806577 659 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 369 464 8.8E-30 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS17500 3819ddbe17bf141be94d4fcc5c806577 659 Gene3D G3DSA:2.60.40.60 568 651 3.6E-5 T 05-07-2017 IPR002126 Cadherin GO:0005509|GO:0007156|GO:0016020 K08M4_RS07035 0d1091d770a899a395d35cdfa68ef97e 241 Gene3D G3DSA:3.10.290.10 10 72 2.0E-14 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS07035 0d1091d770a899a395d35cdfa68ef97e 241 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 74 230 3.3E-40 T 05-07-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 K08M4_RS07035 0d1091d770a899a395d35cdfa68ef97e 241 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 107 121 - T 05-07-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 K08M4_RS07035 0d1091d770a899a395d35cdfa68ef97e 241 SUPERFAMILY SSF55120 69 233 1.76E-40 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS07035 0d1091d770a899a395d35cdfa68ef97e 241 SUPERFAMILY SSF55174 10 92 2.09E-10 T 05-07-2017 K08M4_RS07035 0d1091d770a899a395d35cdfa68ef97e 241 SMART SM00363 10 67 2.5E-4 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS07035 0d1091d770a899a395d35cdfa68ef97e 241 Pfam PF00849 RNA pseudouridylate synthase 70 200 5.6E-15 T 05-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS17015 f2488bc366c9592a23ef9143495211f2 279 Pfam PF14863 Alkyl sulfatase dimerisation 185 237 4.9E-6 T 05-07-2017 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 K08M4_RS17015 f2488bc366c9592a23ef9143495211f2 279 SUPERFAMILY SSF48452 173 254 1.14E-14 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS17015 f2488bc366c9592a23ef9143495211f2 279 SMART SM00028 187 220 15.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS17015 f2488bc366c9592a23ef9143495211f2 279 SMART SM00028 221 254 0.11 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS17015 f2488bc366c9592a23ef9143495211f2 279 Gene3D G3DSA:1.25.40.10 155 252 2.0E-14 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS17200 b4cda9c0ce67d5b5851d253d15f2d076 155 Gene3D G3DSA:1.10.10.10 1 51 4.3E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS17200 b4cda9c0ce67d5b5851d253d15f2d076 155 SUPERFAMILY SSF54909 66 151 2.95E-16 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel K08M4_RS17200 b4cda9c0ce67d5b5851d253d15f2d076 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 7.6E-16 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS17200 b4cda9c0ce67d5b5851d253d15f2d076 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 7.6E-16 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS17200 b4cda9c0ce67d5b5851d253d15f2d076 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 7.6E-16 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS17200 b4cda9c0ce67d5b5851d253d15f2d076 155 SMART SM00344 3 112 7.7E-35 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 K08M4_RS17200 b4cda9c0ce67d5b5851d253d15f2d076 155 Pfam PF01037 Lrp/AsnC ligand binding domain 69 143 4.7E-18 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS17200 b4cda9c0ce67d5b5851d253d15f2d076 155 Gene3D G3DSA:3.30.70.920 56 152 8.3E-23 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS17200 b4cda9c0ce67d5b5851d253d15f2d076 155 SUPERFAMILY SSF46785 2 62 1.78E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS17200 b4cda9c0ce67d5b5851d253d15f2d076 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 49 1.8E-17 T 05-07-2017 K08M4_RS05040 cc21b2dd0917fef06bd3719c0855f040 159 Pfam PF07308 Protein of unknown function (DUF1456) 85 151 2.8E-21 T 05-07-2017 IPR009921 Domain of unknown function DUF1456 K08M4_RS05040 cc21b2dd0917fef06bd3719c0855f040 159 Pfam PF07308 Protein of unknown function (DUF1456) 3 70 2.9E-20 T 05-07-2017 IPR009921 Domain of unknown function DUF1456 K08M4_RS18685 fec88592a05b93d6f60d7475ecea3b4e 262 Pfam PF01435 Peptidase family M48 60 245 4.3E-46 T 05-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 K08M4_RS18685 fec88592a05b93d6f60d7475ecea3b4e 262 Gene3D G3DSA:3.30.2010.10 58 139 3.7E-19 T 05-07-2017 K08M4_RS16485 b115b32a3e7d349c21cb2ccdc4d3f8ec 153 SUPERFAMILY SSF55804 5 152 1.44E-29 T 05-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 K08M4_RS16485 b115b32a3e7d349c21cb2ccdc4d3f8ec 153 Gene3D G3DSA:3.40.930.10 5 152 7.9E-41 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS16485 b115b32a3e7d349c21cb2ccdc4d3f8ec 153 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 57 73 - T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS16485 b115b32a3e7d349c21cb2ccdc4d3f8ec 153 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 20 152 3.3E-26 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS12200 5f353c7dea66fb6e11ccdd5b25a8fa64 306 Gene3D G3DSA:3.40.50.10490 11 256 4.5E-89 T 05-07-2017 K08M4_RS12200 5f353c7dea66fb6e11ccdd5b25a8fa64 306 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 9 302 43.647 T 05-07-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 K08M4_RS12200 5f353c7dea66fb6e11ccdd5b25a8fa64 306 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 13 303 1.2E-130 T 05-07-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 K08M4_RS12200 5f353c7dea66fb6e11ccdd5b25a8fa64 306 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 192 209 - T 05-07-2017 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 K08M4_RS12200 5f353c7dea66fb6e11ccdd5b25a8fa64 306 Pfam PF13580 SIS domain 49 172 3.8E-9 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 K08M4_RS12200 5f353c7dea66fb6e11ccdd5b25a8fa64 306 SUPERFAMILY SSF53697 12 256 1.66E-72 T 05-07-2017 K08M4_RS03565 75a0a8383202be5452606f1ab67d8c61 207 Gene3D G3DSA:3.40.50.1820 12 179 2.3E-30 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS03565 75a0a8383202be5452606f1ab67d8c61 207 SUPERFAMILY SSF53474 9 204 2.38E-25 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS03565 75a0a8383202be5452606f1ab67d8c61 207 Pfam PF00561 alpha/beta hydrolase fold 15 121 6.7E-8 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS17610 bd18c4b8f88bb82f7f27edf9a809e3cc 469 SUPERFAMILY SSF141868 236 460 1.01E-42 T 05-07-2017 IPR001633 EAL domain K08M4_RS17610 bd18c4b8f88bb82f7f27edf9a809e3cc 469 SMART SM00052 215 464 1.9E-22 T 05-07-2017 IPR001633 EAL domain K08M4_RS17610 bd18c4b8f88bb82f7f27edf9a809e3cc 469 Pfam PF00563 EAL domain 225 459 8.6E-53 T 05-07-2017 IPR001633 EAL domain K08M4_RS17610 bd18c4b8f88bb82f7f27edf9a809e3cc 469 Gene3D G3DSA:3.20.20.450 225 460 2.1E-42 T 05-07-2017 IPR001633 EAL domain K08M4_RS03790 2982245a58cc2c537e60752a7e9ab78e 314 Pfam PF14572 Phosphoribosyl synthetase-associated domain 204 313 6.3E-30 T 05-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 K08M4_RS03790 2982245a58cc2c537e60752a7e9ab78e 314 Gene3D G3DSA:3.40.50.2020 160 286 1.4E-53 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS03790 2982245a58cc2c537e60752a7e9ab78e 314 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 129 144 - T 05-07-2017 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 K08M4_RS03790 2982245a58cc2c537e60752a7e9ab78e 314 Gene3D G3DSA:3.40.50.2020 2 159 2.0E-72 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS03790 2982245a58cc2c537e60752a7e9ab78e 314 SMART SM01400 4 121 5.9E-77 T 05-07-2017 K08M4_RS03790 2982245a58cc2c537e60752a7e9ab78e 314 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 4 314 2.4E-125 T 05-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 K08M4_RS03790 2982245a58cc2c537e60752a7e9ab78e 314 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 4 121 7.3E-50 T 05-07-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 K08M4_RS03790 2982245a58cc2c537e60752a7e9ab78e 314 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 4 314 49.595 T 05-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 K08M4_RS03790 2982245a58cc2c537e60752a7e9ab78e 314 SUPERFAMILY SSF53271 69 306 7.32E-67 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS21055 bbf7af8f1dd25fda0f80ab5a1d1c2055 595 Gene3D G3DSA:3.40.50.300 286 452 1.2E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21055 bbf7af8f1dd25fda0f80ab5a1d1c2055 595 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 490 499 - T 05-07-2017 IPR025944 Sigma-54 interaction domain, conserved site K08M4_RS21055 bbf7af8f1dd25fda0f80ab5a1d1c2055 595 SUPERFAMILY SSF52540 285 520 3.07E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21055 bbf7af8f1dd25fda0f80ab5a1d1c2055 595 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 305 318 - T 05-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 K08M4_RS21055 bbf7af8f1dd25fda0f80ab5a1d1c2055 595 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 368 383 - T 05-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 K08M4_RS21055 bbf7af8f1dd25fda0f80ab5a1d1c2055 595 Pfam PF00158 Sigma-54 interaction domain 285 446 1.1E-60 T 05-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 K08M4_RS21055 bbf7af8f1dd25fda0f80ab5a1d1c2055 595 Gene3D G3DSA:1.10.8.60 456 524 2.6E-14 T 05-07-2017 K08M4_RS21055 bbf7af8f1dd25fda0f80ab5a1d1c2055 595 Pfam PF01590 GAF domain 90 185 1.3E-7 T 05-07-2017 IPR003018 GAF domain GO:0005515 K08M4_RS21055 bbf7af8f1dd25fda0f80ab5a1d1c2055 595 SUPERFAMILY SSF46689 490 594 5.12E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS21055 bbf7af8f1dd25fda0f80ab5a1d1c2055 595 Pfam PF02954 Bacterial regulatory protein, Fis family 564 590 3.3E-8 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS21055 bbf7af8f1dd25fda0f80ab5a1d1c2055 595 Gene3D G3DSA:1.10.10.60 542 594 9.8E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS21055 bbf7af8f1dd25fda0f80ab5a1d1c2055 595 SMART SM00382 301 445 4.6E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS21055 bbf7af8f1dd25fda0f80ab5a1d1c2055 595 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 575 595 6.2E-6 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS21055 bbf7af8f1dd25fda0f80ab5a1d1c2055 595 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 558 575 6.2E-6 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS19980 206192e737b672736732c90331ef2251 219 Pfam PF05069 Phage virion morphogenesis family 14 106 5.1E-9 T 05-07-2017 IPR006522 Phage virion morphogensis protein K08M4_RS19980 206192e737b672736732c90331ef2251 219 TIGRFAM TIGR01635 tail_comp_S: phage virion morphogenesis protein 9 137 4.0E-27 T 05-07-2017 IPR006522 Phage virion morphogensis protein K08M4_RS11830 60b8b534de306db27e1502be3bcd3c8e 386 SUPERFAMILY SSF50998 30 375 2.22E-86 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily K08M4_RS11830 60b8b534de306db27e1502be3bcd3c8e 386 Gene3D G3DSA:2.140.10.10 1 362 6.7E-76 T 05-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain K08M4_RS11830 60b8b534de306db27e1502be3bcd3c8e 386 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 8 382 1.4E-140 T 05-07-2017 IPR017687 Outer membrane protein assembly factor BamB K08M4_RS11830 60b8b534de306db27e1502be3bcd3c8e 386 Pfam PF13360 PQQ-like domain 76 310 1.0E-53 T 05-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat K08M4_RS11830 60b8b534de306db27e1502be3bcd3c8e 386 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 3 384 41.107 T 05-07-2017 IPR017687 Outer membrane protein assembly factor BamB K08M4_RS11830 60b8b534de306db27e1502be3bcd3c8e 386 SMART SM00564 63 94 3.2E-7 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat K08M4_RS11830 60b8b534de306db27e1502be3bcd3c8e 386 SMART SM00564 281 312 3.9 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat K08M4_RS11830 60b8b534de306db27e1502be3bcd3c8e 386 SMART SM00564 322 353 2.1 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat K08M4_RS11830 60b8b534de306db27e1502be3bcd3c8e 386 SMART SM00564 147 178 1.1E-4 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat K08M4_RS11830 60b8b534de306db27e1502be3bcd3c8e 386 SMART SM00564 107 138 9.2E-4 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat K08M4_RS11830 60b8b534de306db27e1502be3bcd3c8e 386 SMART SM00564 192 223 92.0 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat K08M4_RS11830 60b8b534de306db27e1502be3bcd3c8e 386 SMART SM00564 243 274 1.2 T 05-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat K08M4_RS07495 b748d40812a585d997513cbbc03bd790 295 SUPERFAMILY SSF50182 128 189 1.08E-14 T 05-07-2017 IPR010920 LSM domain K08M4_RS07495 b748d40812a585d997513cbbc03bd790 295 Gene3D G3DSA:2.30.30.60 143 188 4.5E-14 T 05-07-2017 K08M4_RS07495 b748d40812a585d997513cbbc03bd790 295 Pfam PF00924 Mechanosensitive ion channel 89 286 5.6E-35 T 05-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 K08M4_RS07495 b748d40812a585d997513cbbc03bd790 295 Gene3D G3DSA:3.30.70.100 200 285 5.4E-4 T 05-07-2017 K08M4_RS07495 b748d40812a585d997513cbbc03bd790 295 SUPERFAMILY SSF82689 200 288 1.7E-6 T 05-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 K08M4_RS18995 481b2954e17a8e7ddbca0fafe2e10f24 165 Pfam PF11066 Protein of unknown function (DUF2867) 14 157 1.2E-36 T 05-07-2017 IPR021295 Protein of unknown function DUF2867 K08M4_RS07850 8a78556b6808cfa6b54b79bec86ac8d8 457 TIGRFAM TIGR00155 pqiA_fam: integral membrane protein, PqiA family 51 444 1.4E-104 T 05-07-2017 IPR005219 Conserved hypothetical protein CHP00155 K08M4_RS07850 8a78556b6808cfa6b54b79bec86ac8d8 457 Gene3D G3DSA:3.90.10.10 42 86 2.2E-5 T 05-07-2017 K08M4_RS07850 8a78556b6808cfa6b54b79bec86ac8d8 457 Gene3D G3DSA:3.90.10.10 241 284 2.2E-5 T 05-07-2017 K08M4_RS07850 8a78556b6808cfa6b54b79bec86ac8d8 457 Pfam PF04403 Paraquat-inducible protein A 95 246 6.8E-36 T 05-07-2017 IPR007498 Paraquat-inducible protein A K08M4_RS07850 8a78556b6808cfa6b54b79bec86ac8d8 457 Pfam PF04403 Paraquat-inducible protein A 290 446 1.6E-46 T 05-07-2017 IPR007498 Paraquat-inducible protein A K08M4_RS11105 4bd7533fcf792e2eff841c58d0ef443a 261 Gene3D G3DSA:3.40.50.150 74 213 2.7E-18 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS11105 4bd7533fcf792e2eff841c58d0ef443a 261 Pfam PF08241 Methyltransferase domain 71 125 5.7E-10 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 K08M4_RS11105 4bd7533fcf792e2eff841c58d0ef443a 261 SUPERFAMILY SSF53335 73 212 3.79E-20 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS04275 ee974cfcc42eceb72a5bac516e5f61c2 164 Gene3D G3DSA:2.40.50.180 48 94 2.7E-9 T 05-07-2017 K08M4_RS04275 ee974cfcc42eceb72a5bac516e5f61c2 164 SMART SM00260 16 153 4.6E-50 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS04275 ee974cfcc42eceb72a5bac516e5f61c2 164 SUPERFAMILY SSF50341 14 158 1.15E-41 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS04275 ee974cfcc42eceb72a5bac516e5f61c2 164 Pfam PF01584 CheW-like domain 20 155 2.8E-40 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS04275 ee974cfcc42eceb72a5bac516e5f61c2 164 Gene3D G3DSA:2.30.30.40 95 146 1.5E-8 T 05-07-2017 K08M4_RS00825 7a00bbc4c7dcb90b8a7d856e1273f739 121 Gene3D G3DSA:3.30.1390.10 52 121 4.5E-33 T 05-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like K08M4_RS00825 7a00bbc4c7dcb90b8a7d856e1273f739 121 SUPERFAMILY SSF48300 4 57 1.44E-14 T 05-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS00825 7a00bbc4c7dcb90b8a7d856e1273f739 121 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 121 8.7E-46 T 05-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS00825 7a00bbc4c7dcb90b8a7d856e1273f739 121 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 121 24.567 T 05-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS00825 7a00bbc4c7dcb90b8a7d856e1273f739 121 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 55 121 2.9E-30 T 05-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS00825 7a00bbc4c7dcb90b8a7d856e1273f739 121 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 121 7.0E-17 T 05-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS00825 7a00bbc4c7dcb90b8a7d856e1273f739 121 Gene3D G3DSA:1.20.5.710 2 51 2.9E-21 T 05-07-2017 K08M4_RS00825 7a00bbc4c7dcb90b8a7d856e1273f739 121 SUPERFAMILY SSF54736 51 121 2.09E-24 T 05-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like K08M4_RS00825 7a00bbc4c7dcb90b8a7d856e1273f739 121 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 4 50 8.1E-15 T 05-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 Pfam PF02867 Ribonucleotide reductase, barrel domain 173 689 1.6E-137 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 11 710 0.0 T 05-07-2017 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 SUPERFAMILY SSF51998 171 694 1.62E-178 T 05-07-2017 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 PRINTS PR01183 Ribonucleotide reductase large chain signature 461 483 2.2E-34 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 PRINTS PR01183 Ribonucleotide reductase large chain signature 573 600 2.2E-34 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 PRINTS PR01183 Ribonucleotide reductase large chain signature 247 266 2.2E-34 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 PRINTS PR01183 Ribonucleotide reductase large chain signature 489 512 2.2E-34 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 PRINTS PR01183 Ribonucleotide reductase large chain signature 378 389 2.2E-34 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 PRINTS PR01183 Ribonucleotide reductase large chain signature 422 445 2.2E-34 T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 95 167 1.7E-10 T 05-07-2017 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 562 584 - T 05-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 Gene3D G3DSA:3.20.70.20 103 293 5.8E-53 T 05-07-2017 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 Gene3D G3DSA:3.20.70.20 346 509 5.8E-53 T 05-07-2017 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 Gene3D G3DSA:3.20.70.20 573 688 5.8E-53 T 05-07-2017 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 99 693 3.9E-160 T 05-07-2017 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 SUPERFAMILY SSF48168 11 170 3.92E-53 T 05-07-2017 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS08910 916f9809d4288401d42eada79daad285 710 Pfam PF08343 Ribonucleotide reductase N-terminal 12 93 2.9E-30 T 05-07-2017 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 K08M4_RS08110 5839d4da21d29078e66d5c1521e06fdc 324 Pfam PF13533 Biotin-lipoyl like 45 89 6.0E-11 T 05-07-2017 K08M4_RS08110 5839d4da21d29078e66d5c1521e06fdc 324 Gene3D G3DSA:2.40.50.100 42 76 6.6E-11 T 05-07-2017 K08M4_RS08110 5839d4da21d29078e66d5c1521e06fdc 324 Gene3D G3DSA:2.40.50.100 203 236 6.6E-11 T 05-07-2017 K08M4_RS08110 5839d4da21d29078e66d5c1521e06fdc 324 SUPERFAMILY SSF111369 35 121 1.57E-6 T 05-07-2017 K08M4_RS08110 5839d4da21d29078e66d5c1521e06fdc 324 Pfam PF13437 HlyD family secretion protein 206 282 1.6E-5 T 05-07-2017 K08M4_RS21510 b5542f7caf044043d97648a055177849 218 Gene3D G3DSA:3.40.109.10 4 216 3.6E-52 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 K08M4_RS21510 b5542f7caf044043d97648a055177849 218 SUPERFAMILY SSF55469 6 216 7.85E-54 T 05-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 K08M4_RS21510 b5542f7caf044043d97648a055177849 218 Pfam PF00881 Nitroreductase family 10 193 2.7E-19 T 05-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 K08M4_RS14530 d24d610d8d8e636b8b0b932abf7ab986 292 TIGRFAM TIGR00950 2A78: carboxylate/amino acid/amine transporter 11 273 2.8E-73 T 05-07-2017 IPR004779 Carboxylate/Amino Acid/Amine Transporter GO:0016021 K08M4_RS14530 d24d610d8d8e636b8b0b932abf7ab986 292 SUPERFAMILY SSF103481 35 130 4.58E-6 T 05-07-2017 K08M4_RS14530 d24d610d8d8e636b8b0b932abf7ab986 292 Pfam PF00892 EamA-like transporter family 139 275 9.2E-7 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS14530 d24d610d8d8e636b8b0b932abf7ab986 292 SUPERFAMILY SSF103481 184 275 5.1E-6 T 05-07-2017 K08M4_RS10230 a5d59f36d723ef699a17ed8a58b9d0d6 355 Gene3D G3DSA:3.40.50.1100 48 143 2.8E-24 T 05-07-2017 K08M4_RS10230 a5d59f36d723ef699a17ed8a58b9d0d6 355 SUPERFAMILY SSF53686 22 335 1.44E-70 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme K08M4_RS10230 a5d59f36d723ef699a17ed8a58b9d0d6 355 Gene3D G3DSA:3.40.50.1100 144 332 3.0E-37 T 05-07-2017 K08M4_RS10230 a5d59f36d723ef699a17ed8a58b9d0d6 355 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 316 1.1E-42 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme K08M4_RS15290 2616dee060497e4ec2242a4b8202d4a7 305 SUPERFAMILY SSF82689 186 285 9.29E-21 T 05-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 K08M4_RS15290 2616dee060497e4ec2242a4b8202d4a7 305 Gene3D G3DSA:3.30.70.100 187 273 7.1E-17 T 05-07-2017 K08M4_RS15290 2616dee060497e4ec2242a4b8202d4a7 305 SUPERFAMILY SSF82861 31 117 2.35E-13 T 05-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 K08M4_RS15290 2616dee060497e4ec2242a4b8202d4a7 305 Pfam PF00924 Mechanosensitive ion channel 74 273 1.8E-47 T 05-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 K08M4_RS15290 2616dee060497e4ec2242a4b8202d4a7 305 SUPERFAMILY SSF50182 119 184 1.5E-15 T 05-07-2017 IPR010920 LSM domain K08M4_RS15290 2616dee060497e4ec2242a4b8202d4a7 305 Gene3D G3DSA:2.30.30.60 134 183 3.5E-14 T 05-07-2017 K08M4_RS02900 01e5470a47cb5c05baeb1d8da6810248 253 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 252 54.277 T 05-07-2017 IPR005224 Sugar fermentation stimulation protein K08M4_RS02900 01e5470a47cb5c05baeb1d8da6810248 253 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 4 246 2.1E-70 T 05-07-2017 IPR005224 Sugar fermentation stimulation protein K08M4_RS02900 01e5470a47cb5c05baeb1d8da6810248 253 Pfam PF03749 Sugar fermentation stimulation protein 13 243 1.2E-70 T 05-07-2017 IPR005224 Sugar fermentation stimulation protein K08M4_RS07305 9173c45fc2de7da7631fe57c11e03b3a 292 Gene3D G3DSA:1.10.10.10 1 78 6.3E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS07305 9173c45fc2de7da7631fe57c11e03b3a 292 Pfam PF03466 LysR substrate binding domain 89 289 1.9E-31 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS07305 9173c45fc2de7da7631fe57c11e03b3a 292 Gene3D G3DSA:3.40.190.10 177 255 7.8E-5 T 05-07-2017 K08M4_RS07305 9173c45fc2de7da7631fe57c11e03b3a 292 SUPERFAMILY SSF53850 90 291 1.81E-33 T 05-07-2017 K08M4_RS07305 9173c45fc2de7da7631fe57c11e03b3a 292 Gene3D G3DSA:3.40.190.10 105 176 9.4E-13 T 05-07-2017 K08M4_RS07305 9173c45fc2de7da7631fe57c11e03b3a 292 SUPERFAMILY SSF46785 1 85 8.41E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS07305 9173c45fc2de7da7631fe57c11e03b3a 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.5E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS07305 9173c45fc2de7da7631fe57c11e03b3a 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.5E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS07305 9173c45fc2de7da7631fe57c11e03b3a 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.5E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS07305 9173c45fc2de7da7631fe57c11e03b3a 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.5E-17 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS07615 e88e6460ed9f23c21117e5280069f458 297 SUPERFAMILY SSF52402 15 233 3.72E-53 T 05-07-2017 K08M4_RS07615 e88e6460ed9f23c21117e5280069f458 297 PIRSF PIRSF004976 1 281 2.6E-69 T 05-07-2017 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 Reactome: R-HSA-6782315 K08M4_RS07615 e88e6460ed9f23c21117e5280069f458 297 Pfam PF01171 PP-loop family 41 200 3.6E-15 T 05-07-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 K08M4_RS07615 e88e6460ed9f23c21117e5280069f458 297 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 8 269 55.546 T 05-07-2017 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 Reactome: R-HSA-6782315 K08M4_RS07615 e88e6460ed9f23c21117e5280069f458 297 Gene3D G3DSA:3.40.50.620 21 205 1.7E-22 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS15615 0f00c12368e9d3f03491ea63f0adefba 295 Pfam PF00589 Phage integrase family 109 269 1.1E-38 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS15615 0f00c12368e9d3f03491ea63f0adefba 295 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 12 92 1.8E-18 T 05-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 K08M4_RS15615 0f00c12368e9d3f03491ea63f0adefba 295 Gene3D G3DSA:1.10.150.130 11 91 1.0E-5 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal K08M4_RS15615 0f00c12368e9d3f03491ea63f0adefba 295 Gene3D G3DSA:1.10.443.10 104 284 6.5E-45 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS15615 0f00c12368e9d3f03491ea63f0adefba 295 SUPERFAMILY SSF56349 11 279 9.12E-54 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS02360 531ccf5a4ec9600bf194491d5c4aeade 217 SUPERFAMILY SSF75445 127 198 8.63E-23 T 05-07-2017 K08M4_RS02360 531ccf5a4ec9600bf194491d5c4aeade 217 Gene3D G3DSA:3.40.50.1360 1 136 1.1E-56 T 05-07-2017 K08M4_RS02360 531ccf5a4ec9600bf194491d5c4aeade 217 Gene3D G3DSA:3.30.70.260 137 196 6.4E-28 T 05-07-2017 K08M4_RS02360 531ccf5a4ec9600bf194491d5c4aeade 217 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 217 32.565 T 05-07-2017 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 K08M4_RS02360 531ccf5a4ec9600bf194491d5c4aeade 217 SUPERFAMILY SSF100950 1 146 2.42E-46 T 05-07-2017 K08M4_RS02360 531ccf5a4ec9600bf194491d5c4aeade 217 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 214 5.1E-66 T 05-07-2017 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 K08M4_RS02360 531ccf5a4ec9600bf194491d5c4aeade 217 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 49 213 5.8E-55 T 05-07-2017 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 K08M4_RS19940 d6841aa5e557c35a679509544661018a 632 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 49 388 7.3E-26 T 05-07-2017 IPR010090 Phage tail tape measure protein K08M4_RS19940 d6841aa5e557c35a679509544661018a 632 Pfam PF10145 Phage-related minor tail protein 94 285 1.6E-27 T 05-07-2017 IPR010090 Phage tail tape measure protein K08M4_RS00980 affbd7d6623a427fdd52084f2378a7ec 583 SUPERFAMILY SSF56176 499 570 6.25E-8 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 K08M4_RS00980 affbd7d6623a427fdd52084f2378a7ec 583 Pfam PF02080 TrkA-C domain 418 484 6.2E-13 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS00980 affbd7d6623a427fdd52084f2378a7ec 583 SMART SM01091 493 573 2.6E-11 T 05-07-2017 IPR005170 Transporter-associated domain K08M4_RS00980 affbd7d6623a427fdd52084f2378a7ec 583 Gene3D G3DSA:3.30.465.10 500 567 4.2E-8 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 K08M4_RS00980 affbd7d6623a427fdd52084f2378a7ec 583 Gene3D G3DSA:3.30.70.1450 420 485 1.3E-8 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS00980 affbd7d6623a427fdd52084f2378a7ec 583 Pfam PF00999 Sodium/hydrogen exchanger family 15 384 2.1E-54 T 05-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 K08M4_RS00980 affbd7d6623a427fdd52084f2378a7ec 583 Hamap MF_01075 K(+)/H(+) antiporter NhaP2 [nhaP2]. 1 576 48.664 T 05-07-2017 IPR023729 K(+)/H(+) antiporter NhaP2 GO:0005451|GO:0006812|GO:0006813|GO:0006884|GO:0016021 K08M4_RS00980 affbd7d6623a427fdd52084f2378a7ec 583 SUPERFAMILY SSF116726 411 485 4.71E-11 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS00980 affbd7d6623a427fdd52084f2378a7ec 583 Pfam PF03471 Transporter associated domain 496 569 1.3E-5 T 05-07-2017 IPR005170 Transporter-associated domain K08M4_RS12570 a0836229b8bc6238c3223668465c0454 353 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 7 352 34.838 T 05-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 K08M4_RS12570 a0836229b8bc6238c3223668465c0454 353 Gene3D G3DSA:3.40.50.2000 1 195 2.4E-77 T 05-07-2017 K08M4_RS12570 a0836229b8bc6238c3223668465c0454 353 Gene3D G3DSA:3.40.50.2000 251 333 2.6E-8 T 05-07-2017 K08M4_RS12570 a0836229b8bc6238c3223668465c0454 353 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 8 144 7.3E-48 T 05-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 K08M4_RS12570 a0836229b8bc6238c3223668465c0454 353 SUPERFAMILY SSF53756 5 352 4.32E-126 T 05-07-2017 K08M4_RS12570 a0836229b8bc6238c3223668465c0454 353 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 348 1.2E-118 T 05-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 K08M4_RS12570 a0836229b8bc6238c3223668465c0454 353 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 184 342 3.4E-35 T 05-07-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 K08M4_RS12045 b454986eca3f5ce015fcbf76d5cdcaa4 304 Pfam PF04381 Putative exonuclease, RdgC 1 298 3.6E-122 T 05-07-2017 IPR007476 Putative exonuclease, RdgC GO:0006310 K08M4_RS12045 b454986eca3f5ce015fcbf76d5cdcaa4 304 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 301 38.28 T 05-07-2017 IPR007476 Putative exonuclease, RdgC GO:0006310 K08M4_RS16215 d912040a4ecd217edcddc534fdd1dbb7 130 Gene3D G3DSA:3.10.450.10 47 119 1.7E-14 T 05-07-2017 K08M4_RS16215 d912040a4ecd217edcddc534fdd1dbb7 130 Pfam PF00031 Cystatin domain 57 108 1.1E-7 T 05-07-2017 IPR000010 Cystatin domain GO:0004869 K08M4_RS16215 d912040a4ecd217edcddc534fdd1dbb7 130 SUPERFAMILY SSF54403 47 118 4.68E-16 T 05-07-2017 K08M4_RS16215 d912040a4ecd217edcddc534fdd1dbb7 130 ProSitePatterns PS00287 Cysteine proteases inhibitors signature. 85 98 - T 05-07-2017 IPR018073 Proteinase inhibitor I25, cystatin, conserved site K08M4_RS06185 2b4b24a7b2d44f6b47e2ac0f9be25bde 310 Pfam PF00294 pfkB family carbohydrate kinase 5 303 7.7E-61 T 05-07-2017 IPR011611 Carbohydrate kinase PfkB K08M4_RS06185 2b4b24a7b2d44f6b47e2ac0f9be25bde 310 Gene3D G3DSA:3.40.1190.20 1 299 4.6E-73 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS06185 2b4b24a7b2d44f6b47e2ac0f9be25bde 310 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 256 269 - T 05-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 K08M4_RS06185 2b4b24a7b2d44f6b47e2ac0f9be25bde 310 SUPERFAMILY SSF53613 1 302 3.43E-73 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS02945 69e7f85a36ce3303e06978e01cd50636 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 253 3.5E-15 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS02945 69e7f85a36ce3303e06978e01cd50636 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 341 534 8.9E-9 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS02945 69e7f85a36ce3303e06978e01cd50636 541 Gene3D G3DSA:1.10.3720.10 284 536 1.0E-35 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS02945 69e7f85a36ce3303e06978e01cd50636 541 Gene3D G3DSA:1.10.3720.10 7 262 1.5E-36 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS02945 69e7f85a36ce3303e06978e01cd50636 541 SUPERFAMILY SSF161098 282 535 3.64E-41 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS02945 69e7f85a36ce3303e06978e01cd50636 541 SUPERFAMILY SSF161098 6 254 5.36E-44 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS16985 932a396b16e72d3281ad6219cfd6db9b 172 ProSitePatterns PS00893 Nudix box signature. 52 73 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 K08M4_RS16985 932a396b16e72d3281ad6219cfd6db9b 172 Pfam PF00293 NUDIX domain 23 145 6.1E-15 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 K08M4_RS16985 932a396b16e72d3281ad6219cfd6db9b 172 Gene3D G3DSA:3.90.79.10 23 144 9.8E-19 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS16985 932a396b16e72d3281ad6219cfd6db9b 172 SUPERFAMILY SSF55811 9 142 3.25E-20 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS02300 2016e69b4869f02b08ce58529ff94705 234 SMART SM00448 4 114 2.9E-41 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS02300 2016e69b4869f02b08ce58529ff94705 234 SMART SM00862 151 225 4.6E-18 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS02300 2016e69b4869f02b08ce58529ff94705 234 SUPERFAMILY SSF52172 2 127 1.18E-39 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS02300 2016e69b4869f02b08ce58529ff94705 234 Pfam PF00072 Response regulator receiver domain 6 115 3.9E-30 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS02300 2016e69b4869f02b08ce58529ff94705 234 SUPERFAMILY SSF46894 125 227 1.02E-21 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS02300 2016e69b4869f02b08ce58529ff94705 234 Gene3D G3DSA:3.40.50.2300 4 124 1.3E-39 T 05-07-2017 K08M4_RS02300 2016e69b4869f02b08ce58529ff94705 234 Gene3D G3DSA:1.10.10.10 127 226 2.1E-24 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS02300 2016e69b4869f02b08ce58529ff94705 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 7.8E-19 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS19785 1fbfd5d6d6813824cc5acf88431d81b3 271 SUPERFAMILY SSF161098 73 256 5.36E-30 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS19785 1fbfd5d6d6813824cc5acf88431d81b3 271 Gene3D G3DSA:1.10.3720.10 72 266 4.3E-20 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS19785 1fbfd5d6d6813824cc5acf88431d81b3 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 260 1.3E-29 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07365 7398c27d55e63f277182b83a663e9965 410 SMART SM00382 54 243 1.4E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS07365 7398c27d55e63f277182b83a663e9965 410 SUPERFAMILY SSF52540 39 265 1.43E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07365 7398c27d55e63f277182b83a663e9965 410 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 38 394 1.0E-123 T 05-07-2017 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 K08M4_RS07365 7398c27d55e63f277182b83a663e9965 410 Pfam PF00005 ABC transporter 45 193 7.6E-33 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS07365 7398c27d55e63f277182b83a663e9965 410 Gene3D G3DSA:3.10.580.10 274 392 6.1E-11 T 05-07-2017 K08M4_RS07365 7398c27d55e63f277182b83a663e9965 410 SUPERFAMILY SSF54631 275 398 2.16E-10 T 05-07-2017 K08M4_RS07365 7398c27d55e63f277182b83a663e9965 410 Gene3D G3DSA:3.40.50.300 2 268 1.5E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07365 7398c27d55e63f277182b83a663e9965 410 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 SUPERFAMILY SSF53187 401 486 6.29E-63 T 05-07-2017 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 SUPERFAMILY SSF53187 16 186 6.29E-63 T 05-07-2017 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 PIRSF PIRSF016599 5 489 7.8E-214 T 05-07-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 PRINTS PR00934 X-His dipeptidase (M25) signature 454 476 1.9E-88 T 05-07-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 PRINTS PR00934 X-His dipeptidase (M25) signature 163 181 1.9E-88 T 05-07-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 PRINTS PR00934 X-His dipeptidase (M25) signature 210 227 1.9E-88 T 05-07-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 PRINTS PR00934 X-His dipeptidase (M25) signature 84 103 1.9E-88 T 05-07-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 PRINTS PR00934 X-His dipeptidase (M25) signature 105 123 1.9E-88 T 05-07-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 PRINTS PR00934 X-His dipeptidase (M25) signature 139 156 1.9E-88 T 05-07-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 PRINTS PR00934 X-His dipeptidase (M25) signature 367 385 1.9E-88 T 05-07-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 PRINTS PR00934 X-His dipeptidase (M25) signature 432 448 1.9E-88 T 05-07-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 PRINTS PR00934 X-His dipeptidase (M25) signature 255 274 1.9E-88 T 05-07-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 13 486 1.8E-177 T 05-07-2017 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 Pfam PF07687 Peptidase dimerisation domain 211 296 2.3E-7 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 Pfam PF01546 Peptidase family M20/M25/M40 77 473 8.2E-20 T 05-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 Gene3D G3DSA:3.40.630.10 6 185 8.2E-107 T 05-07-2017 K08M4_RS03455 67e6288dddc0d66e9c9b27e19f3ed57d 490 Gene3D G3DSA:3.40.630.10 401 488 8.2E-107 T 05-07-2017 K08M4_RS19695 eb6c9d1e21e52e3b3047362866710a22 310 Gene3D G3DSA:3.40.50.1980 30 154 2.1E-32 T 05-07-2017 K08M4_RS19695 eb6c9d1e21e52e3b3047362866710a22 310 SUPERFAMILY SSF53807 26 302 1.45E-61 T 05-07-2017 K08M4_RS19695 eb6c9d1e21e52e3b3047362866710a22 310 Gene3D G3DSA:3.40.50.1980 155 309 1.8E-29 T 05-07-2017 K08M4_RS19695 eb6c9d1e21e52e3b3047362866710a22 310 Pfam PF01497 Periplasmic binding protein 50 286 3.4E-29 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 K08M4_RS18675 9ae5b05f9f5751ca64c0cb6da197fefe 77 Pfam PF11869 Protein of unknown function (DUF3389) 1 76 3.3E-36 T 05-07-2017 IPR021811 Protein of unknown function DUF3389 K08M4_RS01770 4700ca42a98117cd1052be4018883058 234 Gene3D G3DSA:3.40.50.300 1 224 2.9E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01770 4700ca42a98117cd1052be4018883058 234 SUPERFAMILY SSF52540 1 229 4.71E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01770 4700ca42a98117cd1052be4018883058 234 Pfam PF00005 ABC transporter 18 157 3.4E-33 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS01770 4700ca42a98117cd1052be4018883058 234 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS01770 4700ca42a98117cd1052be4018883058 234 TIGRFAM TIGR01277 thiQ: thiamine ABC transporter, ATP-binding protein 3 210 7.9E-98 T 05-07-2017 IPR005968 Thiamine ABC transporter, ATP-binding protein ThiQ GO:0005524|GO:0006810|GO:0016021|GO:0042626 K08M4_RS01770 4700ca42a98117cd1052be4018883058 234 SMART SM00382 24 206 2.4E-18 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS03630 e9f807428623b612405cfb66701f6c13 341 Pfam PF06144 DNA polymerase III, delta subunit 20 189 5.4E-47 T 05-07-2017 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 K08M4_RS03630 e9f807428623b612405cfb66701f6c13 341 Gene3D G3DSA:3.40.50.300 1 138 5.0E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03630 e9f807428623b612405cfb66701f6c13 341 SUPERFAMILY SSF52540 1 208 6.31E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03630 e9f807428623b612405cfb66701f6c13 341 SUPERFAMILY SSF48019 211 333 4.08E-33 T 05-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 K08M4_RS03630 e9f807428623b612405cfb66701f6c13 341 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 16 331 3.7E-103 T 05-07-2017 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 K08M4_RS03630 e9f807428623b612405cfb66701f6c13 341 Gene3D G3DSA:1.20.272.20 222 334 1.4E-46 T 05-07-2017 K08M4_RS03630 e9f807428623b612405cfb66701f6c13 341 Gene3D G3DSA:1.10.8.60 144 221 7.1E-32 T 05-07-2017 K08M4_RS03630 e9f807428623b612405cfb66701f6c13 341 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 213 331 1.0E-34 T 05-07-2017 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS20745 2fc57f9106f615f349f274df76f0a6ec 230 Pfam PF01925 Sulfite exporter TauE/SafE 3 221 3.5E-23 T 05-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 K08M4_RS11640 e1aeceb1e49bc7ce86e26362294bb1f3 212 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 77 114 - T 05-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 K08M4_RS11640 e1aeceb1e49bc7ce86e26362294bb1f3 212 Pfam PF14437 MafB19-like deaminase 28 173 1.4E-30 T 05-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 K08M4_RS11640 e1aeceb1e49bc7ce86e26362294bb1f3 212 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 32 173 44.044 T 05-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 K08M4_RS11640 e1aeceb1e49bc7ce86e26362294bb1f3 212 SUPERFAMILY SSF53927 21 177 1.12E-54 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 K08M4_RS11640 e1aeceb1e49bc7ce86e26362294bb1f3 212 Gene3D G3DSA:3.40.140.10 22 171 4.9E-58 T 05-07-2017 K08M4_RS16285 2dc43bbbf08973c14c287f85dd3a099b 276 Pfam PF02540 NAD synthase 21 270 5.7E-65 T 05-07-2017 IPR022310 NAD/GMP synthase K08M4_RS16285 2dc43bbbf08973c14c287f85dd3a099b 276 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 15 274 31.443 T 05-07-2017 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 K08M4_RS16285 2dc43bbbf08973c14c287f85dd3a099b 276 Gene3D G3DSA:3.40.50.620 3 275 2.9E-69 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS16285 2dc43bbbf08973c14c287f85dd3a099b 276 SUPERFAMILY SSF52402 2 276 2.05E-79 T 05-07-2017 K08M4_RS16285 2dc43bbbf08973c14c287f85dd3a099b 276 TIGRFAM TIGR00552 nadE: NAD+ synthetase 26 272 1.1E-66 T 05-07-2017 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 K08M4_RS11075 a4286e3c9601ca9e6f9588fc895d66cb 281 SUPERFAMILY SSF56235 2 253 1.2E-51 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS11075 a4286e3c9601ca9e6f9588fc895d66cb 281 Gene3D G3DSA:3.60.20.10 1 252 4.6E-69 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS11075 a4286e3c9601ca9e6f9588fc895d66cb 281 Pfam PF13230 Glutamine amidotransferases class-II 1 259 5.0E-115 T 05-07-2017 IPR026869 Putative glutamine amidotransferase type 2 K08M4_RS17020 e20ab3e7028ac1c87a804c1253922915 421 Gene3D G3DSA:2.70.70.10 241 382 3.8E-45 T 05-07-2017 K08M4_RS17020 e20ab3e7028ac1c87a804c1253922915 421 SUPERFAMILY SSF51261 136 381 4.45E-63 T 05-07-2017 IPR011055 Duplicated hybrid motif K08M4_RS17020 e20ab3e7028ac1c87a804c1253922915 421 Pfam PF01551 Peptidase family M23 286 379 3.1E-30 T 05-07-2017 IPR016047 Peptidase M23 K08M4_RS14080 88344e0b104cf01e6c52211b7f2eac35 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 187 200 1.7E-6 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS14080 88344e0b104cf01e6c52211b7f2eac35 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 109 122 1.7E-6 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS14080 88344e0b104cf01e6c52211b7f2eac35 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 13 24 1.7E-6 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS14080 88344e0b104cf01e6c52211b7f2eac35 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 160 180 1.7E-6 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS14080 88344e0b104cf01e6c52211b7f2eac35 235 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 148 198 5.7E-13 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS14080 88344e0b104cf01e6c52211b7f2eac35 235 Gene3D G3DSA:3.40.50.1000 100 221 7.6E-39 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS14080 88344e0b104cf01e6c52211b7f2eac35 235 Gene3D G3DSA:3.40.50.1000 11 27 7.6E-39 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS14080 88344e0b104cf01e6c52211b7f2eac35 235 SUPERFAMILY SSF56784 11 229 3.86E-44 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS14080 88344e0b104cf01e6c52211b7f2eac35 235 Pfam PF13419 Haloacid dehalogenase-like hydrolase 16 198 7.6E-33 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS10430 34242674e5b238b83119908bf0610202 271 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 119 210 7.4E-18 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 K08M4_RS10430 34242674e5b238b83119908bf0610202 271 Gene3D G3DSA:3.90.470.20 8 130 6.9E-28 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 K08M4_RS10430 34242674e5b238b83119908bf0610202 271 SUPERFAMILY SSF56214 118 202 8.02E-22 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 K08M4_RS10430 34242674e5b238b83119908bf0610202 271 SUPERFAMILY SSF56214 231 266 8.02E-22 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 K08M4_RS10430 34242674e5b238b83119908bf0610202 271 Gene3D G3DSA:3.90.470.20 131 249 1.2E-25 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 K08M4_RS10430 34242674e5b238b83119908bf0610202 271 SUPERFAMILY SSF56214 6 106 1.64E-19 T 05-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 K08M4_RS20185 0f78529bc5eb422dcdfa51cbbcbaf9f5 323 Gene3D G3DSA:1.10.3470.10 4 321 4.1E-99 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS20185 0f78529bc5eb422dcdfa51cbbcbaf9f5 323 Pfam PF01032 FecCD transport family 14 319 2.5E-95 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 K08M4_RS20185 0f78529bc5eb422dcdfa51cbbcbaf9f5 323 SUPERFAMILY SSF81345 3 319 3.01E-83 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS09265 27d5e86c6d09e3dab8b6bc6a5d4f3204 419 Gene3D G3DSA:1.10.3860.10 12 408 1.6E-112 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS09265 27d5e86c6d09e3dab8b6bc6a5d4f3204 419 Pfam PF00375 Sodium:dicarboxylate symporter family 15 403 3.0E-119 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS09265 27d5e86c6d09e3dab8b6bc6a5d4f3204 419 SUPERFAMILY SSF118215 15 403 1.15E-109 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS09265 27d5e86c6d09e3dab8b6bc6a5d4f3204 419 PRINTS PR00173 Glutamate-aspartate symporter signature 332 351 2.6E-54 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS09265 27d5e86c6d09e3dab8b6bc6a5d4f3204 419 PRINTS PR00173 Glutamate-aspartate symporter signature 230 249 2.6E-54 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS09265 27d5e86c6d09e3dab8b6bc6a5d4f3204 419 PRINTS PR00173 Glutamate-aspartate symporter signature 297 323 2.6E-54 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS09265 27d5e86c6d09e3dab8b6bc6a5d4f3204 419 PRINTS PR00173 Glutamate-aspartate symporter signature 358 378 2.6E-54 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS09265 27d5e86c6d09e3dab8b6bc6a5d4f3204 419 PRINTS PR00173 Glutamate-aspartate symporter signature 195 214 2.6E-54 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS09265 27d5e86c6d09e3dab8b6bc6a5d4f3204 419 PRINTS PR00173 Glutamate-aspartate symporter signature 7 27 2.6E-54 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS09265 27d5e86c6d09e3dab8b6bc6a5d4f3204 419 PRINTS PR00173 Glutamate-aspartate symporter signature 48 68 2.6E-54 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS09265 27d5e86c6d09e3dab8b6bc6a5d4f3204 419 PRINTS PR00173 Glutamate-aspartate symporter signature 78 103 2.6E-54 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS09265 27d5e86c6d09e3dab8b6bc6a5d4f3204 419 PRINTS PR00173 Glutamate-aspartate symporter signature 147 169 2.6E-54 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS09900 0a7b0f65970cf5e73ec44cb7a56264d4 252 SUPERFAMILY SSF53167 6 249 9.69E-72 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 K08M4_RS09900 0a7b0f65970cf5e73ec44cb7a56264d4 252 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 5 251 2.5E-110 T 05-07-2017 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3 K08M4_RS09900 0a7b0f65970cf5e73ec44cb7a56264d4 252 Gene3D G3DSA:3.40.50.1580 4 251 2.0E-83 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 K08M4_RS09900 0a7b0f65970cf5e73ec44cb7a56264d4 252 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 65 80 - T 05-07-2017 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS09900 0a7b0f65970cf5e73ec44cb7a56264d4 252 Pfam PF01048 Phosphorylase superfamily 20 243 1.0E-39 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 K08M4_RS01710 d276651cbd9f5a17b039749f2f874811 96 Pfam PF10795 Protein of unknown function (DUF2607) 6 93 2.7E-34 T 05-07-2017 IPR019731 Protein of unknown function DUF2607 K08M4_RS03025 ae61681b690e4bb93008e39899d3ac5e 113 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 94 111 - T 05-07-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site K08M4_RS03025 ae61681b690e4bb93008e39899d3ac5e 113 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 113 35.593 T 05-07-2017 IPR023063 FeS cluster insertion protein ErpA GO:0016226 K08M4_RS03025 ae61681b690e4bb93008e39899d3ac5e 113 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 9 113 1.7E-36 T 05-07-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 K08M4_RS03025 ae61681b690e4bb93008e39899d3ac5e 113 SUPERFAMILY SSF89360 7 102 1.39E-28 T 05-07-2017 IPR000361 FeS cluster biogenesis K08M4_RS03025 ae61681b690e4bb93008e39899d3ac5e 113 Pfam PF01521 Iron-sulphur cluster biosynthesis 8 108 5.8E-18 T 05-07-2017 IPR000361 FeS cluster biogenesis K08M4_RS03025 ae61681b690e4bb93008e39899d3ac5e 113 Gene3D G3DSA:2.60.300.12 5 99 7.3E-30 T 05-07-2017 IPR000361 FeS cluster biogenesis K08M4_RS01275 ffd8d7ad646356a41b0d0cd90f61a87e 572 Pfam PF03958 Bacterial type II/III secretion system short domain 253 318 1.8E-10 T 05-07-2017 IPR005644 NolW-like K08M4_RS01275 ffd8d7ad646356a41b0d0cd90f61a87e 572 PRINTS PR00811 Bacterial general secretion pathway protein D signature 535 553 8.8E-20 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS01275 ffd8d7ad646356a41b0d0cd90f61a87e 572 PRINTS PR00811 Bacterial general secretion pathway protein D signature 558 572 8.8E-20 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS01275 ffd8d7ad646356a41b0d0cd90f61a87e 572 PRINTS PR00811 Bacterial general secretion pathway protein D signature 443 453 8.8E-20 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS01275 ffd8d7ad646356a41b0d0cd90f61a87e 572 PRINTS PR00811 Bacterial general secretion pathway protein D signature 408 432 8.8E-20 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS01275 ffd8d7ad646356a41b0d0cd90f61a87e 572 PRINTS PR00811 Bacterial general secretion pathway protein D signature 318 328 8.8E-20 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS01275 ffd8d7ad646356a41b0d0cd90f61a87e 572 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 154 570 7.5E-161 T 05-07-2017 IPR013355 Type IV pilus secretin PilQ GO:0009297|GO:0009306 K08M4_RS01275 ffd8d7ad646356a41b0d0cd90f61a87e 572 SMART SM00965 179 227 2.3E-9 T 05-07-2017 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 K08M4_RS01275 ffd8d7ad646356a41b0d0cd90f61a87e 572 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 516 549 - T 05-07-2017 IPR004845 Type II secretion system GspD, conserved site GO:0008565 K08M4_RS01275 ffd8d7ad646356a41b0d0cd90f61a87e 572 Pfam PF00263 Bacterial type II and III secretion system protein 412 570 1.2E-45 T 05-07-2017 IPR004846 Type II/III secretion system GO:0009306 K08M4_RS05935 1777eb597793e15c4701096c3824d62d 223 Gene3D G3DSA:3.40.50.880 1 222 1.3E-65 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS05935 1777eb597793e15c4701096c3824d62d 223 SUPERFAMILY SSF52317 1 222 2.65E-55 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS05935 1777eb597793e15c4701096c3824d62d 223 Pfam PF01965 DJ-1/PfpI family 27 220 5.3E-14 T 05-07-2017 IPR002818 DJ-1/PfpI K08M4_RS09295 9e42aa3ef7878e1cbc678eb30685656b 484 SUPERFAMILY SSF56024 66 313 2.47E-52 T 05-07-2017 K08M4_RS09295 9e42aa3ef7878e1cbc678eb30685656b 484 SMART SM00155 219 246 9.4E-5 T 05-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 K08M4_RS09295 9e42aa3ef7878e1cbc678eb30685656b 484 SMART SM00155 397 424 1.8E-6 T 05-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 K08M4_RS09295 9e42aa3ef7878e1cbc678eb30685656b 484 SUPERFAMILY SSF56024 273 469 4.93E-47 T 05-07-2017 K08M4_RS09295 9e42aa3ef7878e1cbc678eb30685656b 484 Pfam PF13396 Phospholipase_D-nuclease N-terminal 20 59 5.3E-7 T 05-07-2017 IPR027379 Cardiolipin synthase N-terminal K08M4_RS09295 9e42aa3ef7878e1cbc678eb30685656b 484 Pfam PF13091 PLD-like domain 327 447 1.8E-24 T 05-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 K08M4_RS09295 9e42aa3ef7878e1cbc678eb30685656b 484 Pfam PF13091 PLD-like domain 134 267 2.5E-15 T 05-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 K08M4_RS09295 9e42aa3ef7878e1cbc678eb30685656b 484 Hamap MF_00190 Cardiolipin synthase A [clsA]. 2 484 49.019 T 05-07-2017 IPR030840 Cardiolipin synthase A GO:0008808|GO:0016780|GO:0032049 K08M4_RS09295 9e42aa3ef7878e1cbc678eb30685656b 484 Gene3D G3DSA:3.30.870.10 112 310 2.6E-37 T 05-07-2017 K08M4_RS09295 9e42aa3ef7878e1cbc678eb30685656b 484 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 11 484 7.8E-148 T 05-07-2017 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 K08M4_RS09295 9e42aa3ef7878e1cbc678eb30685656b 484 Gene3D G3DSA:3.30.870.10 311 461 1.1E-35 T 05-07-2017 K08M4_RS16955 0d0b4fb7b2994f1f4c28c4af7635aaf6 333 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 66 311 1.8E-24 T 05-07-2017 IPR001761 Periplasmic binding protein/LacI sugar binding domain K08M4_RS16955 0d0b4fb7b2994f1f4c28c4af7635aaf6 333 Gene3D G3DSA:3.40.50.2300 175 332 4.9E-41 T 05-07-2017 K08M4_RS16955 0d0b4fb7b2994f1f4c28c4af7635aaf6 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 54 1.9E-18 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS16955 0d0b4fb7b2994f1f4c28c4af7635aaf6 333 SUPERFAMILY SSF53822 64 316 2.36E-57 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS16955 0d0b4fb7b2994f1f4c28c4af7635aaf6 333 SUPERFAMILY SSF47413 6 65 3.26E-15 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS16955 0d0b4fb7b2994f1f4c28c4af7635aaf6 333 SMART SM00354 7 77 2.6E-28 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS16955 0d0b4fb7b2994f1f4c28c4af7635aaf6 333 Gene3D G3DSA:3.40.50.2300 64 174 1.4E-39 T 05-07-2017 K08M4_RS16955 0d0b4fb7b2994f1f4c28c4af7635aaf6 333 Gene3D G3DSA:1.10.260.40 6 62 2.2E-19 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS14560 2df5463c4f0f1ad9f62bd4a59ea617a8 279 SUPERFAMILY SSF53335 9 275 2.63E-95 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS14560 2df5463c4f0f1ad9f62bd4a59ea617a8 279 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 277 1.4E-114 T 05-07-2017 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 K08M4_RS14560 2df5463c4f0f1ad9f62bd4a59ea617a8 279 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 161 167 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 K08M4_RS14560 2df5463c4f0f1ad9f62bd4a59ea617a8 279 Gene3D G3DSA:3.40.50.150 1 279 8.7E-116 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS14560 2df5463c4f0f1ad9f62bd4a59ea617a8 279 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 266 41.227 T 05-07-2017 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 K08M4_RS14560 2df5463c4f0f1ad9f62bd4a59ea617a8 279 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 241 247 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 K08M4_RS02810 4056b9f400d1450c6248d0452223ba32 199 SUPERFAMILY SSF55846 21 197 7.85E-64 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 K08M4_RS02810 4056b9f400d1450c6248d0452223ba32 199 Gene3D G3DSA:3.40.80.10 23 197 5.5E-64 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 K08M4_RS02810 4056b9f400d1450c6248d0452223ba32 199 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 46 185 2.1E-20 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 K08M4_RS02810 4056b9f400d1450c6248d0452223ba32 199 SMART SM00644 34 185 2.0E-51 T 05-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 K08M4_RS21090 9f1b258fb2941ba1d67a84ba628f9548 233 Gene3D G3DSA:2.30.110.10 16 192 6.7E-42 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 K08M4_RS21090 9f1b258fb2941ba1d67a84ba628f9548 233 SUPERFAMILY SSF50475 10 199 4.22E-30 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 K08M4_RS21090 9f1b258fb2941ba1d67a84ba628f9548 233 SMART SM00903 26 181 0.0095 T 05-07-2017 IPR002563 Flavin reductase like domain GO:0010181 K08M4_RS21090 9f1b258fb2941ba1d67a84ba628f9548 233 Pfam PF01613 Flavin reductase like domain 35 167 2.6E-12 T 05-07-2017 IPR002563 Flavin reductase like domain GO:0010181 K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 10 393 2.1E-90 T 05-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 PRINTS PR00714 Phosphomannose isomerase type I signature 90 111 1.2E-67 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 PRINTS PR00714 Phosphomannose isomerase type I signature 248 267 1.2E-67 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 PRINTS PR00714 Phosphomannose isomerase type I signature 232 247 1.2E-67 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 PRINTS PR00714 Phosphomannose isomerase type I signature 42 57 1.2E-67 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 PRINTS PR00714 Phosphomannose isomerase type I signature 135 158 1.2E-67 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 PRINTS PR00714 Phosphomannose isomerase type I signature 14 32 1.2E-67 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 PRINTS PR00714 Phosphomannose isomerase type I signature 267 286 1.2E-67 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 PRINTS PR00714 Phosphomannose isomerase type I signature 286 305 1.2E-67 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 135 143 - T 05-07-2017 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 ProSitePatterns PS00966 Phosphomannose isomerase type I signature 2. 267 292 - T 05-07-2017 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 Gene3D G3DSA:2.60.120.10 250 285 1.9E-64 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 Gene3D G3DSA:2.60.120.10 16 149 1.9E-64 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 Gene3D G3DSA:2.60.120.10 300 384 6.2E-6 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 Gene3D G3DSA:1.10.441.10 150 243 1.6E-29 T 05-07-2017 K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 Gene3D G3DSA:1.10.441.10 286 299 1.6E-29 T 05-07-2017 K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 SUPERFAMILY SSF51182 9 391 6.09E-98 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 PIRSF PIRSF001480 8 401 5.0E-101 T 05-07-2017 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS21340 3c1e2474675bbedb45b22bc281e06f4a 401 Pfam PF01238 Phosphomannose isomerase type I 12 357 2.5E-82 T 05-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 K08M4_RS18655 21ca9073e3abe6ac2a876ac6c0f24a6f 279 Gene3D G3DSA:2.60.120.330 7 261 1.1E-56 T 05-07-2017 IPR027443 Isopenicillin N synthase-like K08M4_RS18655 21ca9073e3abe6ac2a876ac6c0f24a6f 279 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 152 253 4.1E-15 T 05-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 K08M4_RS18655 21ca9073e3abe6ac2a876ac6c0f24a6f 279 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 11 95 6.0E-10 T 05-07-2017 IPR026992 Non-haem dioxygenase N-terminal domain K08M4_RS18655 21ca9073e3abe6ac2a876ac6c0f24a6f 279 SUPERFAMILY SSF51197 7 276 1.81E-60 T 05-07-2017 K08M4_RS08005 fbddded4b1827500850dafb383df7f82 634 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 16 65 1.6E-13 T 05-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 K08M4_RS08005 fbddded4b1827500850dafb383df7f82 634 Gene3D G3DSA:3.30.300.30 505 608 2.3E-22 T 05-07-2017 K08M4_RS08005 fbddded4b1827500850dafb383df7f82 634 SUPERFAMILY SSF56801 12 632 5.49E-155 T 05-07-2017 K08M4_RS08005 fbddded4b1827500850dafb383df7f82 634 Gene3D G3DSA:2.30.38.10 426 504 4.1E-7 T 05-07-2017 K08M4_RS08005 fbddded4b1827500850dafb383df7f82 634 ProSitePatterns PS00455 Putative AMP-binding domain signature. 246 257 - T 05-07-2017 IPR020845 AMP-binding, conserved site K08M4_RS08005 fbddded4b1827500850dafb383df7f82 634 Pfam PF00501 AMP-binding enzyme 76 510 2.1E-82 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 K08M4_RS08005 fbddded4b1827500850dafb383df7f82 634 Pfam PF13193 AMP-binding enzyme C-terminal domain 519 598 3.5E-24 T 05-07-2017 IPR025110 AMP-binding enzyme C-terminal domain K08M4_RS08005 fbddded4b1827500850dafb383df7f82 634 Gene3D G3DSA:3.40.50.980 252 415 2.2E-28 T 05-07-2017 K08M4_RS08005 fbddded4b1827500850dafb383df7f82 634 Gene3D G3DSA:3.40.50.980 76 251 1.5E-36 T 05-07-2017 K08M4_RS21705 7a2142ba4383369adc4862f8164b100c 920 Gene3D G3DSA:3.30.830.10 502 722 4.3E-19 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 K08M4_RS21705 7a2142ba4383369adc4862f8164b100c 920 Gene3D G3DSA:3.30.830.10 21 253 6.4E-50 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 K08M4_RS21705 7a2142ba4383369adc4862f8164b100c 920 SUPERFAMILY SSF63411 503 717 9.25E-24 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 K08M4_RS21705 7a2142ba4383369adc4862f8164b100c 920 SUPERFAMILY SSF63411 33 240 2.27E-43 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 K08M4_RS21705 7a2142ba4383369adc4862f8164b100c 920 Gene3D G3DSA:3.30.830.10 768 911 9.1E-11 T 05-07-2017 IPR011237 Peptidase M16 domain GO:0046872 K08M4_RS21705 7a2142ba4383369adc4862f8164b100c 920 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 63 86 - T 05-07-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 K08M4_RS21705 7a2142ba4383369adc4862f8164b100c 920 Pfam PF05193 Peptidase M16 inactive domain 676 851 6.0E-13 T 05-07-2017 IPR007863 Peptidase M16, C-terminal K08M4_RS21705 7a2142ba4383369adc4862f8164b100c 920 Pfam PF05193 Peptidase M16 inactive domain 201 378 1.5E-12 T 05-07-2017 IPR007863 Peptidase M16, C-terminal K08M4_RS21705 7a2142ba4383369adc4862f8164b100c 920 Pfam PF00675 Insulinase (Peptidase family M16) 50 163 8.1E-27 T 05-07-2017 IPR011765 Peptidase M16, N-terminal K08M4_RS21705 7a2142ba4383369adc4862f8164b100c 920 SUPERFAMILY SSF63411 761 911 3.84E-16 T 05-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 K08M4_RS11030 830eddafd13421a4e1a268cb95b36855 484 Pfam PF01435 Peptidase family M48 70 252 2.1E-28 T 05-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 K08M4_RS11030 830eddafd13421a4e1a268cb95b36855 484 Gene3D G3DSA:3.30.2010.10 63 147 6.5E-19 T 05-07-2017 K08M4_RS11030 830eddafd13421a4e1a268cb95b36855 484 Hamap MF_00997 Beta-barrel assembly-enhancing protease [bepA]. 1 483 40.066 T 05-07-2017 IPR030873 Beta-barrel assembly-enhancing protease GO:0006508|GO:0008237|GO:0016020|GO:0061077 K08M4_RS11030 830eddafd13421a4e1a268cb95b36855 484 Pfam PF14559 Tetratricopeptide repeat 352 417 1.2E-9 T 05-07-2017 K08M4_RS11030 830eddafd13421a4e1a268cb95b36855 484 SUPERFAMILY SSF48452 311 455 1.45E-18 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS11030 830eddafd13421a4e1a268cb95b36855 484 Gene3D G3DSA:1.25.40.10 311 456 1.0E-21 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS12585 16902b602b80711c37cabc434e33b6b6 360 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 6.3E-6 T 05-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 K08M4_RS12585 16902b602b80711c37cabc434e33b6b6 360 ProSitePatterns PS01348 MraY family signature 2. 189 200 - T 05-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 K08M4_RS12585 16902b602b80711c37cabc434e33b6b6 360 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 05-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 K08M4_RS12585 16902b602b80711c37cabc434e33b6b6 360 Pfam PF00953 Glycosyl transferase family 4 99 283 2.9E-37 T 05-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 K08M4_RS12585 16902b602b80711c37cabc434e33b6b6 360 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 358 25.389 T 05-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 K08M4_RS12585 16902b602b80711c37cabc434e33b6b6 360 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 37 360 1.5E-156 T 05-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 K08M4_RS05610 c5be1c835a941f28362f6431156f8479 346 SUPERFAMILY SSF81345 16 340 1.44E-77 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS05610 c5be1c835a941f28362f6431156f8479 346 Gene3D G3DSA:1.10.3470.10 17 341 3.8E-95 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS05610 c5be1c835a941f28362f6431156f8479 346 Pfam PF01032 FecCD transport family 29 340 1.2E-89 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 K08M4_RS15235 39c110c5e8e6a65e4ca4c4a98182c317 86 Pfam PF16691 Domain of unknown function (DUF5062) 6 86 7.6E-27 T 05-07-2017 IPR032036 Protein of unknown function DUF5062 K08M4_RS09235 ada2fa720d3be67cba33a5a65f989245 535 TIGRFAM TIGR00565 trpE_proteo: anthranilate synthase component I 22 519 6.4E-224 T 05-07-2017 IPR005257 Anthranilate synthase component I, TrpE-like, bacterial GO:0004049|GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 K08M4_RS09235 ada2fa720d3be67cba33a5a65f989245 535 Pfam PF00425 chorismate binding enzyme 247 507 2.0E-86 T 05-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal K08M4_RS09235 ada2fa720d3be67cba33a5a65f989245 535 PIRSF PIRSF001373 3 526 1.7E-257 T 05-07-2017 IPR005257 Anthranilate synthase component I, TrpE-like, bacterial GO:0004049|GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 K08M4_RS09235 ada2fa720d3be67cba33a5a65f989245 535 PRINTS PR00095 Anthranilate synthase component I signature 449 463 5.1E-23 T 05-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 K08M4_RS09235 ada2fa720d3be67cba33a5a65f989245 535 PRINTS PR00095 Anthranilate synthase component I signature 369 382 5.1E-23 T 05-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 K08M4_RS09235 ada2fa720d3be67cba33a5a65f989245 535 PRINTS PR00095 Anthranilate synthase component I signature 464 478 5.1E-23 T 05-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 K08M4_RS09235 ada2fa720d3be67cba33a5a65f989245 535 PRINTS PR00095 Anthranilate synthase component I signature 355 368 5.1E-23 T 05-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 K08M4_RS09235 ada2fa720d3be67cba33a5a65f989245 535 Gene3D G3DSA:3.60.120.10 12 519 6.3E-164 T 05-07-2017 IPR005801 ADC synthase GO:0009058 K08M4_RS09235 ada2fa720d3be67cba33a5a65f989245 535 Pfam PF04715 Anthranilate synthase component I, N terminal region 24 195 2.5E-16 T 05-07-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 K08M4_RS09235 ada2fa720d3be67cba33a5a65f989245 535 SUPERFAMILY SSF56322 12 518 2.62E-158 T 05-07-2017 IPR005801 ADC synthase GO:0009058 K08M4_RS03140 99fdc024830ba9ee7be7b75b188fe0b6 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 1.0E-37 T 05-07-2017 K08M4_RS03140 99fdc024830ba9ee7be7b75b188fe0b6 89 SMART SM01387 8 88 5.2E-52 T 05-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS03140 99fdc024830ba9ee7be7b75b188fe0b6 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.395 T 05-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS03140 99fdc024830ba9ee7be7b75b188fe0b6 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 05-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS03140 99fdc024830ba9ee7be7b75b188fe0b6 89 SUPERFAMILY SSF47060 3 89 5.59E-35 T 05-07-2017 IPR009068 S15/NS1, RNA-binding K08M4_RS03140 99fdc024830ba9ee7be7b75b188fe0b6 89 Gene3D G3DSA:1.10.287.10 3 89 4.1E-39 T 05-07-2017 IPR009068 S15/NS1, RNA-binding K08M4_RS03140 99fdc024830ba9ee7be7b75b188fe0b6 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 1.3E-38 T 05-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS03140 99fdc024830ba9ee7be7b75b188fe0b6 89 Pfam PF00312 Ribosomal protein S15 8 88 2.4E-36 T 05-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS04090 e454515b21d9b0e36f104a81117cf3c2 396 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 142 2.6E-12 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS04090 e454515b21d9b0e36f104a81117cf3c2 396 Gene3D G3DSA:1.20.1330.10 301 353 6.9E-13 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS04090 e454515b21d9b0e36f104a81117cf3c2 396 Gene3D G3DSA:1.20.1330.10 56 170 6.9E-13 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS04090 e454515b21d9b0e36f104a81117cf3c2 396 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 4 396 1.4E-94 T 05-07-2017 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 K08M4_RS04090 e454515b21d9b0e36f104a81117cf3c2 396 SUPERFAMILY SSF64518 1 396 9.94E-68 T 05-07-2017 K08M4_RS13210 2f19f1db01b7a7b6aee327bc075a4d39 290 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 2 263 4.4E-123 T 05-07-2017 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 K08M4_RS13210 2f19f1db01b7a7b6aee327bc075a4d39 290 SUPERFAMILY SSF53448 2 269 8.14E-65 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS13210 2f19f1db01b7a7b6aee327bc075a4d39 290 Pfam PF00483 Nucleotidyl transferase 9 265 2.4E-32 T 05-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 K08M4_RS13210 2f19f1db01b7a7b6aee327bc075a4d39 290 Gene3D G3DSA:3.90.550.10 3 274 4.4E-68 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS16570 425f21e00d003445644296d274771418 407 Gene3D G3DSA:2.40.50.100 246 269 1.1E-10 T 05-07-2017 K08M4_RS16570 425f21e00d003445644296d274771418 407 Gene3D G3DSA:2.40.50.100 72 99 1.1E-10 T 05-07-2017 K08M4_RS16570 425f21e00d003445644296d274771418 407 SUPERFAMILY SSF111369 63 155 2.88E-7 T 05-07-2017 K08M4_RS16570 425f21e00d003445644296d274771418 407 SUPERFAMILY SSF111369 196 277 1.44E-7 T 05-07-2017 K08M4_RS16760 47baaa9f06cace17ded985ccf3a914e7 324 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 43 320 2.2E-97 T 05-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 K08M4_RS16760 47baaa9f06cace17ded985ccf3a914e7 324 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 96 118 - T 05-07-2017 IPR030470 UbiA prenyltransferase conserved site K08M4_RS16760 47baaa9f06cace17ded985ccf3a914e7 324 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 41 322 19.254 T 05-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 K08M4_RS16760 47baaa9f06cace17ded985ccf3a914e7 324 Pfam PF01040 UbiA prenyltransferase family 58 303 7.6E-63 T 05-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 K08M4_RS06770 8cc73faf15d11f179c8e0de5192a4df3 68 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 11 61 4.0E-25 T 05-07-2017 IPR010260 Prophage CP4-57 regulatory protein (AlpA) K08M4_RS20910 6361b87a3cf2a3da3fe85865b77c72ec 553 SMART SM01049 44 130 1.3E-16 T 05-07-2017 IPR033480 Single Cache domain 2 K08M4_RS20910 6361b87a3cf2a3da3fe85865b77c72ec 553 Pfam PF17200 Single Cache domain 2 49 188 1.1E-25 T 05-07-2017 IPR033480 Single Cache domain 2 K08M4_RS20910 6361b87a3cf2a3da3fe85865b77c72ec 553 SMART SM00304 222 276 4.3E-7 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS20910 6361b87a3cf2a3da3fe85865b77c72ec 553 SMART SM00283 291 552 1.3E-69 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS20910 6361b87a3cf2a3da3fe85865b77c72ec 553 Pfam PF00672 HAMP domain 204 272 2.5E-8 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS20910 6361b87a3cf2a3da3fe85865b77c72ec 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 12 37 6.2E-21 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS20910 6361b87a3cf2a3da3fe85865b77c72ec 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 389 416 6.2E-21 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS20910 6361b87a3cf2a3da3fe85865b77c72ec 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 418 447 6.2E-21 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS20910 6361b87a3cf2a3da3fe85865b77c72ec 553 SUPERFAMILY SSF58104 244 553 1.57E-72 T 05-07-2017 K08M4_RS20910 6361b87a3cf2a3da3fe85865b77c72ec 553 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 343 551 4.7E-45 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS20910 6361b87a3cf2a3da3fe85865b77c72ec 553 Gene3D G3DSA:1.10.287.950 306 522 1.9E-53 T 05-07-2017 K08M4_RS20910 6361b87a3cf2a3da3fe85865b77c72ec 553 Gene3D G3DSA:3.30.450.20 35 181 3.7E-35 T 05-07-2017 K08M4_RS16235 cfa36d76de4a35428a607c08d5c8f192 727 Gene3D G3DSA:1.20.1220.12 594 726 1.0E-75 T 05-07-2017 K08M4_RS16235 cfa36d76de4a35428a607c08d5c8f192 727 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 725 0.0 T 05-07-2017 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 K08M4_RS16235 cfa36d76de4a35428a607c08d5c8f192 727 Gene3D G3DSA:2.170.170.11 302 339 2.5E-66 T 05-07-2017 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 K08M4_RS16235 cfa36d76de4a35428a607c08d5c8f192 727 Gene3D G3DSA:2.170.170.11 136 268 2.5E-66 T 05-07-2017 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 K08M4_RS16235 cfa36d76de4a35428a607c08d5c8f192 727 Gene3D G3DSA:1.10.1860.10 1 88 9.1E-33 T 05-07-2017 K08M4_RS16235 cfa36d76de4a35428a607c08d5c8f192 727 Pfam PF01274 Malate synthase 18 701 1.7E-180 T 05-07-2017 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 K08M4_RS16235 cfa36d76de4a35428a607c08d5c8f192 727 Gene3D G3DSA:3.20.20.360 89 135 1.1E-143 T 05-07-2017 K08M4_RS16235 cfa36d76de4a35428a607c08d5c8f192 727 Gene3D G3DSA:3.20.20.360 340 589 1.1E-143 T 05-07-2017 K08M4_RS16235 cfa36d76de4a35428a607c08d5c8f192 727 Gene3D G3DSA:3.20.20.360 270 300 1.1E-143 T 05-07-2017 K08M4_RS16235 cfa36d76de4a35428a607c08d5c8f192 727 SUPERFAMILY SSF51645 3 725 1.44E-303 T 05-07-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 K08M4_RS16235 cfa36d76de4a35428a607c08d5c8f192 727 Hamap MF_00641 Malate synthase G [glcB]. 1 727 391.572 T 05-07-2017 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 K08M4_RS10620 91f54eec7fde1459f5f16eacb6312612 253 SUPERFAMILY SSF53474 3 252 8.04E-45 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS10620 91f54eec7fde1459f5f16eacb6312612 253 Gene3D G3DSA:3.40.50.1820 3 253 5.3E-46 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS10620 91f54eec7fde1459f5f16eacb6312612 253 Pfam PF12697 Alpha/beta hydrolase family 16 246 4.7E-24 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS10620 91f54eec7fde1459f5f16eacb6312612 253 PRINTS PR00412 Epoxide hydrolase signature 39 54 3.1E-5 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 K08M4_RS10620 91f54eec7fde1459f5f16eacb6312612 253 PRINTS PR00412 Epoxide hydrolase signature 229 251 3.1E-5 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 K08M4_RS10620 91f54eec7fde1459f5f16eacb6312612 253 PRINTS PR00412 Epoxide hydrolase signature 82 95 3.1E-5 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 K08M4_RS11180 083c7ad1083f7f05cee6c19b426e57cf 166 Gene3D G3DSA:3.30.910.20 99 166 1.5E-32 T 05-07-2017 K08M4_RS11180 083c7ad1083f7f05cee6c19b426e57cf 166 Gene3D G3DSA:3.30.910.20 14 61 1.5E-32 T 05-07-2017 K08M4_RS11180 083c7ad1083f7f05cee6c19b426e57cf 166 Pfam PF03938 Outer membrane protein (OmpH-like) 10 165 8.2E-26 T 05-07-2017 IPR005632 Chaperone protein Skp GO:0051082 K08M4_RS11180 083c7ad1083f7f05cee6c19b426e57cf 166 SMART SM00935 12 166 3.2E-41 T 05-07-2017 IPR005632 Chaperone protein Skp GO:0051082 K08M4_RS11180 083c7ad1083f7f05cee6c19b426e57cf 166 SUPERFAMILY SSF111384 23 165 3.01E-30 T 05-07-2017 IPR024930 Skp domain K08M4_RS11835 849ce4de9238f4088a87d4780142f428 204 SUPERFAMILY SSF48452 89 188 9.05E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS11835 849ce4de9238f4088a87d4780142f428 204 PIRSF PIRSF006170 1 204 9.7E-51 T 05-07-2017 IPR026039 Uncharacterised protein family UPF0070 K08M4_RS11835 849ce4de9238f4088a87d4780142f428 204 Pfam PF09976 Tetratricopeptide repeat-like domain 15 204 2.1E-52 T 05-07-2017 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038 K08M4_RS11835 849ce4de9238f4088a87d4780142f428 204 Gene3D G3DSA:1.25.40.10 82 188 1.2E-4 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS14185 807c4c991a500addb58820fe9b83521b 183 ProSitePatterns PS00893 Nudix box signature. 80 101 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 K08M4_RS14185 807c4c991a500addb58820fe9b83521b 183 Gene3D G3DSA:3.90.79.10 8 181 9.5E-44 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS14185 807c4c991a500addb58820fe9b83521b 183 SUPERFAMILY SSF55811 7 179 6.63E-41 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS14185 807c4c991a500addb58820fe9b83521b 183 Pfam PF00293 NUDIX domain 46 155 4.5E-16 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 K08M4_RS19640 b4c4fbb67dd9cc897e82d47820b53bfe 303 SUPERFAMILY SSF53850 92 302 1.09E-30 T 05-07-2017 K08M4_RS19640 b4c4fbb67dd9cc897e82d47820b53bfe 303 Gene3D G3DSA:3.40.190.10 92 184 1.8E-10 T 05-07-2017 K08M4_RS19640 b4c4fbb67dd9cc897e82d47820b53bfe 303 Gene3D G3DSA:3.40.190.10 291 302 1.8E-10 T 05-07-2017 K08M4_RS19640 b4c4fbb67dd9cc897e82d47820b53bfe 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 7.6E-11 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19640 b4c4fbb67dd9cc897e82d47820b53bfe 303 SUPERFAMILY SSF46785 6 88 7.48E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19640 b4c4fbb67dd9cc897e82d47820b53bfe 303 Gene3D G3DSA:1.10.10.10 5 89 2.2E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19640 b4c4fbb67dd9cc897e82d47820b53bfe 303 Pfam PF03466 LysR substrate binding domain 95 302 5.1E-13 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS19640 b4c4fbb67dd9cc897e82d47820b53bfe 303 Gene3D G3DSA:3.40.190.10 185 273 1.8E-21 T 05-07-2017 K08M4_RS02210 d263217c4d7d7c78ee2884d598756e79 436 Gene3D G3DSA:3.40.50.300 7 193 2.5E-22 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02210 d263217c4d7d7c78ee2884d598756e79 436 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 10 430 4.0E-90 T 05-07-2017 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 K08M4_RS02210 d263217c4d7d7c78ee2884d598756e79 436 Gene3D G3DSA:3.40.50.880 241 384 4.3E-20 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS02210 d263217c4d7d7c78ee2884d598756e79 436 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 241 418 1.7E-32 T 05-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 K08M4_RS02210 d263217c4d7d7c78ee2884d598756e79 436 SUPERFAMILY SSF52540 8 193 2.57E-38 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02210 d263217c4d7d7c78ee2884d598756e79 436 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 10 189 4.7E-22 T 05-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain K08M4_RS02210 d263217c4d7d7c78ee2884d598756e79 436 SUPERFAMILY SSF52317 241 425 1.27E-25 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS02210 d263217c4d7d7c78ee2884d598756e79 436 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 6 422 36.75 T 05-07-2017 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 K08M4_RS15815 4d165d3d5d46ba40b9132ca922fd1569 129 Pfam PF06961 Protein of unknown function (DUF1294) 38 91 1.7E-24 T 05-07-2017 IPR010718 Protein of unknown function DUF1294 K08M4_RS18625 fafd378cefa41e6cadb427a5937e19ac 205 SUPERFAMILY SSF52266 27 204 4.12E-50 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain K08M4_RS18625 fafd378cefa41e6cadb427a5937e19ac 205 Gene3D G3DSA:3.40.50.1110 27 204 2.1E-53 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain K08M4_RS18625 fafd378cefa41e6cadb427a5937e19ac 205 ProSitePatterns PS01098 Lipolytic enzymes "G-D-S-L" family, serine active site. 28 38 - T 05-07-2017 IPR008265 Lipase, GDSL, active site GO:0006629|GO:0016298 Reactome: R-HSA-1482788|Reactome: R-HSA-975634 K08M4_RS18625 fafd378cefa41e6cadb427a5937e19ac 205 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 30 188 3.9E-25 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain K08M4_RS03920 40b590a1628d20df1cb0a41c5a04874a 790 Gene3D G3DSA:1.20.1640.10 234 408 6.6E-18 T 05-07-2017 K08M4_RS03920 40b590a1628d20df1cb0a41c5a04874a 790 Gene3D G3DSA:1.20.1640.10 622 770 1.2E-10 T 05-07-2017 K08M4_RS03920 40b590a1628d20df1cb0a41c5a04874a 790 SUPERFAMILY SSF82866 230 408 7.85E-18 T 05-07-2017 K08M4_RS03920 40b590a1628d20df1cb0a41c5a04874a 790 SUPERFAMILY SSF82866 649 771 1.7E-20 T 05-07-2017 K08M4_RS03920 40b590a1628d20df1cb0a41c5a04874a 790 Pfam PF03176 MMPL family 194 414 1.1E-9 T 05-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 K08M4_RS15995 ba948143f8b05b01f901b4970ec740ed 714 Pfam PF00990 Diguanylate cyclase, GGDEF domain 533 699 1.0E-34 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS15995 ba948143f8b05b01f901b4970ec740ed 714 SUPERFAMILY SSF55073 537 701 1.18E-34 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS15995 ba948143f8b05b01f901b4970ec740ed 714 SUPERFAMILY SSF55781 179 331 5.67E-6 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS15995 ba948143f8b05b01f901b4970ec740ed 714 SUPERFAMILY SSF55781 359 507 3.6E-5 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS15995 ba948143f8b05b01f901b4970ec740ed 714 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 531 701 3.6E-36 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS15995 ba948143f8b05b01f901b4970ec740ed 714 SMART SM00267 521 703 2.0E-44 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS15995 ba948143f8b05b01f901b4970ec740ed 714 Gene3D G3DSA:3.30.70.270 534 702 2.2E-38 T 05-07-2017 K08M4_RS15995 ba948143f8b05b01f901b4970ec740ed 714 Gene3D G3DSA:3.30.450.40 178 331 2.3E-5 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS16325 8ecb5e914f432cc1981a430aa7e110c6 153 Gene3D G3DSA:1.20.5.830 111 153 7.2E-26 T 05-07-2017 IPR027402 LuxT regulator, C-terminal domain K08M4_RS16325 8ecb5e914f432cc1981a430aa7e110c6 153 SUPERFAMILY SSF46689 1 74 8.21E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS16325 8ecb5e914f432cc1981a430aa7e110c6 153 Gene3D G3DSA:1.10.287.790 63 110 3.9E-28 T 05-07-2017 IPR027404 LuxT regulator, helix hairpin domain K08M4_RS16325 8ecb5e914f432cc1981a430aa7e110c6 153 Gene3D G3DSA:1.10.10.60 2 62 1.3E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS16325 8ecb5e914f432cc1981a430aa7e110c6 153 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 1.9E-4 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS05615 801cbdbf9079e0bf74da300e84354492 353 SUPERFAMILY SSF81345 23 349 2.75E-65 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS05615 801cbdbf9079e0bf74da300e84354492 353 Pfam PF01032 FecCD transport family 43 349 3.5E-72 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 K08M4_RS05615 801cbdbf9079e0bf74da300e84354492 353 Gene3D G3DSA:1.10.3470.10 29 352 1.5E-82 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS03675 7ef77f58a76edbde84fe182352690f0b 391 Pfam PF01494 FAD binding domain 4 75 8.3E-6 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 K08M4_RS03675 7ef77f58a76edbde84fe182352690f0b 391 Pfam PF01494 FAD binding domain 147 317 6.6E-22 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 K08M4_RS03675 7ef77f58a76edbde84fe182352690f0b 391 Gene3D G3DSA:3.30.9.10 223 296 3.0E-5 T 05-07-2017 K08M4_RS03675 7ef77f58a76edbde84fe182352690f0b 391 SUPERFAMILY SSF51905 272 383 1.11E-53 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS03675 7ef77f58a76edbde84fe182352690f0b 391 SUPERFAMILY SSF51905 4 175 1.11E-53 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS03675 7ef77f58a76edbde84fe182352690f0b 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 3.5E-20 T 05-07-2017 K08M4_RS03675 7ef77f58a76edbde84fe182352690f0b 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 3.5E-20 T 05-07-2017 K08M4_RS03675 7ef77f58a76edbde84fe182352690f0b 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 3.5E-20 T 05-07-2017 K08M4_RS03675 7ef77f58a76edbde84fe182352690f0b 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 3.5E-20 T 05-07-2017 K08M4_RS03675 7ef77f58a76edbde84fe182352690f0b 391 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 5 390 8.8E-109 T 05-07-2017 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 K08M4_RS03675 7ef77f58a76edbde84fe182352690f0b 391 Gene3D G3DSA:3.50.50.60 2 178 1.8E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS03675 7ef77f58a76edbde84fe182352690f0b 391 Gene3D G3DSA:3.50.50.60 297 317 1.8E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS01475 a5772c578e32e1018f0d824ebc1bae69 100 Pfam PF00276 Ribosomal protein L23 9 95 1.0E-31 T 05-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 K08M4_RS01475 a5772c578e32e1018f0d824ebc1bae69 100 Gene3D G3DSA:3.30.70.330 6 98 1.5E-35 T 05-07-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 K08M4_RS01475 a5772c578e32e1018f0d824ebc1bae69 100 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 8 98 22.715 T 05-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 K08M4_RS01475 a5772c578e32e1018f0d824ebc1bae69 100 ProSitePatterns PS00050 Ribosomal protein L23 signature. 81 96 - T 05-07-2017 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01475 a5772c578e32e1018f0d824ebc1bae69 100 SUPERFAMILY SSF54189 4 92 7.91E-32 T 05-07-2017 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS08920 c4226934b40e5401056fc917c5b31374 73 Gene3D G3DSA:3.40.30.10 1 72 1.9E-24 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS08920 c4226934b40e5401056fc917c5b31374 73 Pfam PF00462 Glutaredoxin 3 61 1.5E-14 T 05-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 K08M4_RS08920 c4226934b40e5401056fc917c5b31374 73 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 3 72 1.9E-27 T 05-07-2017 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 K08M4_RS08920 c4226934b40e5401056fc917c5b31374 73 SUPERFAMILY SSF52833 1 70 2.67E-18 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS04330 81f035320d921ad14b6199cb43f733b3 261 Pfam PF04333 MlaA lipoprotein 46 237 9.0E-63 T 05-07-2017 IPR007428 MlaA lipoprotein GO:0016020 K08M4_RS04330 81f035320d921ad14b6199cb43f733b3 261 PRINTS PR01805 VacJ lipoprotein signature 116 133 4.0E-30 T 05-07-2017 IPR007428 MlaA lipoprotein GO:0016020 K08M4_RS04330 81f035320d921ad14b6199cb43f733b3 261 PRINTS PR01805 VacJ lipoprotein signature 65 81 4.0E-30 T 05-07-2017 IPR007428 MlaA lipoprotein GO:0016020 K08M4_RS04330 81f035320d921ad14b6199cb43f733b3 261 PRINTS PR01805 VacJ lipoprotein signature 153 170 4.0E-30 T 05-07-2017 IPR007428 MlaA lipoprotein GO:0016020 K08M4_RS04330 81f035320d921ad14b6199cb43f733b3 261 PRINTS PR01805 VacJ lipoprotein signature 47 60 4.0E-30 T 05-07-2017 IPR007428 MlaA lipoprotein GO:0016020 K08M4_RS13640 fa60c16219bb6d04f585533e3b82634e 305 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 48 283 9.9E-86 T 05-07-2017 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 K08M4_RS13640 fa60c16219bb6d04f585533e3b82634e 305 Pfam PF02666 Phosphatidylserine decarboxylase 62 280 7.1E-63 T 05-07-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 K08M4_RS13640 fa60c16219bb6d04f585533e3b82634e 305 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 9 285 48.763 T 05-07-2017 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 K08M4_RS21890 882e9c90564c8e23f37fa8fd9f119ad8 659 Pfam PF11826 Protein of unknown function (DUF3346) 289 513 3.1E-138 T 05-07-2017 IPR021781 Protein of unknown function DUF3346 K08M4_RS04835 2310150da14279d2787fc775f63216de 214 Pfam PF00929 Exonuclease 20 195 1.0E-42 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS04835 2310150da14279d2787fc775f63216de 214 TIGRFAM TIGR01298 RNaseT: ribonuclease T 10 209 3.1E-99 T 05-07-2017 IPR005987 Ribonuclease T GO:0004540|GO:0006396 K08M4_RS04835 2310150da14279d2787fc775f63216de 214 Hamap MF_00157 Ribonuclease T [rnt]. 1 214 115.065 T 05-07-2017 IPR005987 Ribonuclease T GO:0004540|GO:0006396 K08M4_RS04835 2310150da14279d2787fc775f63216de 214 Gene3D G3DSA:3.30.420.10 10 210 7.1E-59 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS04835 2310150da14279d2787fc775f63216de 214 SMART SM00479 18 204 5.4E-28 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS04835 2310150da14279d2787fc775f63216de 214 SUPERFAMILY SSF53098 10 208 6.51E-55 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS04465 41f1b1cb392237c059ca4f7c9946d9ac 604 SUPERFAMILY SSF51735 401 497 5.73E-5 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS04465 41f1b1cb392237c059ca4f7c9946d9ac 604 Pfam PF00999 Sodium/hydrogen exchanger family 11 388 9.0E-32 T 05-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 K08M4_RS04465 41f1b1cb392237c059ca4f7c9946d9ac 604 Gene3D G3DSA:3.40.50.720 395 476 1.2E-4 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS16480 7c26527f6fc3ede08520c744dcf4da5e 337 PIRSF PIRSF039012 11 337 7.9E-85 T 05-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 K08M4_RS16480 7c26527f6fc3ede08520c744dcf4da5e 337 SUPERFAMILY SSF53187 28 335 7.61E-53 T 05-07-2017 K08M4_RS16480 7c26527f6fc3ede08520c744dcf4da5e 337 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 56 335 8.2E-61 T 05-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 K08M4_RS16480 7c26527f6fc3ede08520c744dcf4da5e 337 Gene3D G3DSA:3.40.630.10 51 244 8.2E-19 T 05-07-2017 K08M4_RS19240 9dda9581bcae72303f9e7f11b810c30d 359 Gene3D G3DSA:3.40.50.410 101 300 3.0E-25 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS19240 9dda9581bcae72303f9e7f11b810c30d 359 SMART SM00327 100 298 1.5E-21 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS19240 9dda9581bcae72303f9e7f11b810c30d 359 Pfam PF00092 von Willebrand factor type A domain 102 298 2.0E-24 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS19240 9dda9581bcae72303f9e7f11b810c30d 359 SUPERFAMILY SSF53300 98 300 8.16E-34 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS18225 f51cbb5a9e3a597496936414866672c1 709 Gene3D G3DSA:2.170.130.10 21 164 8.0E-33 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS18225 f51cbb5a9e3a597496936414866672c1 709 Pfam PF00593 TonB dependent receptor 467 708 1.5E-24 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS18225 f51cbb5a9e3a597496936414866672c1 709 Gene3D G3DSA:2.40.170.20 168 709 3.7E-117 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS18225 f51cbb5a9e3a597496936414866672c1 709 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 57 708 3.8E-89 T 05-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 K08M4_RS18225 f51cbb5a9e3a597496936414866672c1 709 SUPERFAMILY SSF56935 19 709 1.06E-120 T 05-07-2017 K08M4_RS18225 f51cbb5a9e3a597496936414866672c1 709 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 152 9.9E-18 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS18070 f51cbb5a9e3a597496936414866672c1 709 Gene3D G3DSA:2.170.130.10 21 164 8.0E-33 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS18070 f51cbb5a9e3a597496936414866672c1 709 Pfam PF00593 TonB dependent receptor 467 708 1.5E-24 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS18070 f51cbb5a9e3a597496936414866672c1 709 Gene3D G3DSA:2.40.170.20 168 709 3.7E-117 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS18070 f51cbb5a9e3a597496936414866672c1 709 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 57 708 3.8E-89 T 05-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 K08M4_RS18070 f51cbb5a9e3a597496936414866672c1 709 SUPERFAMILY SSF56935 19 709 1.06E-120 T 05-07-2017 K08M4_RS18070 f51cbb5a9e3a597496936414866672c1 709 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 152 9.9E-18 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS14340 49ca132ee782d9fcb337844cd9873bd6 162 Pfam PF10675 Protein of unknown function (DUF2489) 14 146 8.4E-43 T 05-07-2017 IPR019617 Domain of unknown function DUF2489 K08M4_RS05705 da1aebac516950f86e45c96c3ed91d08 66 Pfam PF14056 Domain of unknown function (DUF4250) 10 61 4.5E-18 T 05-07-2017 IPR025346 Protein of unknown function DUF4250 K08M4_RS10685 563dfc58ea1a86529afe8d4972d06564 320 Hamap MF_00323 Ferrochelatase [hemH]. 5 320 37.496 T 05-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 K08M4_RS10685 563dfc58ea1a86529afe8d4972d06564 320 Gene3D G3DSA:3.40.50.1400 201 318 4.6E-32 T 05-07-2017 K08M4_RS10685 563dfc58ea1a86529afe8d4972d06564 320 Pfam PF00762 Ferrochelatase 6 318 2.5E-108 T 05-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 K08M4_RS10685 563dfc58ea1a86529afe8d4972d06564 320 ProSitePatterns PS00534 Ferrochelatase signature. 189 207 - T 05-07-2017 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 K08M4_RS10685 563dfc58ea1a86529afe8d4972d06564 320 TIGRFAM TIGR00109 hemH: ferrochelatase 4 319 3.9E-104 T 05-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 K08M4_RS10685 563dfc58ea1a86529afe8d4972d06564 320 SUPERFAMILY SSF53800 4 319 2.49E-101 T 05-07-2017 K08M4_RS10685 563dfc58ea1a86529afe8d4972d06564 320 Gene3D G3DSA:3.40.50.1400 4 200 1.3E-67 T 05-07-2017 K08M4_RS12390 e9c68a55f6f1cdd44f33b33ac110f8ee 226 Gene3D G3DSA:3.40.470.10 4 222 1.5E-99 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 K08M4_RS12390 e9c68a55f6f1cdd44f33b33ac110f8ee 226 Pfam PF03167 Uracil DNA glycosylase superfamily 54 209 4.3E-26 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 K08M4_RS12390 e9c68a55f6f1cdd44f33b33ac110f8ee 226 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 5 214 7.4E-86 T 05-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 K08M4_RS12390 e9c68a55f6f1cdd44f33b33ac110f8ee 226 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 57 66 - T 05-07-2017 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 K08M4_RS12390 e9c68a55f6f1cdd44f33b33ac110f8ee 226 SUPERFAMILY SSF52141 4 222 7.52E-93 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 K08M4_RS12390 e9c68a55f6f1cdd44f33b33ac110f8ee 226 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 4 221 40.182 T 05-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 K08M4_RS12390 e9c68a55f6f1cdd44f33b33ac110f8ee 226 SMART SM00987 49 210 2.8E-42 T 05-07-2017 K08M4_RS12390 e9c68a55f6f1cdd44f33b33ac110f8ee 226 SMART SM00986 49 210 2.8E-42 T 05-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 K08M4_RS20505 bedd9676e2cb1de50b15ac0ccca19461 200 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 97 187 7.2E-21 T 05-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 K08M4_RS20505 bedd9676e2cb1de50b15ac0ccca19461 200 SMART SM00702 11 187 2.5E-33 T 05-07-2017 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 K08M4_RS03410 9040b0fa7bc0d69e25167118f45a83d5 309 Gene3D G3DSA:3.90.550.10 1 120 1.9E-12 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS03410 9040b0fa7bc0d69e25167118f45a83d5 309 Pfam PF00535 Glycosyl transferase family 2 8 125 1.3E-13 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 K08M4_RS03410 9040b0fa7bc0d69e25167118f45a83d5 309 SUPERFAMILY SSF53448 2 252 4.5E-32 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS17250 16f304c389222001395906021e77d43d 434 PRINTS PR00811 Bacterial general secretion pathway protein D signature 181 191 1.4E-6 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS17250 16f304c389222001395906021e77d43d 434 PRINTS PR00811 Bacterial general secretion pathway protein D signature 354 372 1.4E-6 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS17250 16f304c389222001395906021e77d43d 434 Pfam PF13629 Pilus formation protein N terminal region 17 86 7.9E-19 T 05-07-2017 IPR032789 Pilus formation protein, N-terminal K08M4_RS17250 16f304c389222001395906021e77d43d 434 Pfam PF00263 Bacterial type II and III secretion system protein 236 389 1.2E-41 T 05-07-2017 IPR004846 Type II/III secretion system GO:0009306 K08M4_RS05735 2c904e02a584e0b9c89eb46685f95573 132 Gene3D G3DSA:3.10.129.10 13 132 2.0E-40 T 05-07-2017 IPR029069 HotDog domain K08M4_RS05735 2c904e02a584e0b9c89eb46685f95573 132 SUPERFAMILY SSF54637 12 131 6.01E-36 T 05-07-2017 IPR029069 HotDog domain K08M4_RS05735 2c904e02a584e0b9c89eb46685f95573 132 Pfam PF03061 Thioesterase superfamily 28 98 1.2E-17 T 05-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 Gene3D G3DSA:3.30.499.10 327 470 2.5E-62 T 05-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 PRINTS PR00415 Aconitase family signature 200 213 3.5E-50 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 PRINTS PR00415 Aconitase family signature 291 305 3.5E-50 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 PRINTS PR00415 Aconitase family signature 87 100 3.5E-50 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 PRINTS PR00415 Aconitase family signature 348 359 3.5E-50 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 PRINTS PR00415 Aconitase family signature 404 417 3.5E-50 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 PRINTS PR00415 Aconitase family signature 214 227 3.5E-50 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 PRINTS PR00415 Aconitase family signature 113 121 3.5E-50 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 PRINTS PR00415 Aconitase family signature 138 153 3.5E-50 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 PRINTS PR00415 Aconitase family signature 124 137 3.5E-50 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 7 470 2.0E-262 T 05-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 Pfam PF00330 Aconitase family (aconitate hydratase) 12 462 1.5E-153 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 SUPERFAMILY SSF53732 5 470 1.14E-162 T 05-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 Gene3D G3DSA:3.30.499.10 7 163 2.7E-23 T 05-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 ProSitePatterns PS01244 Aconitase family signature 2. 404 417 - T 05-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 Gene3D G3DSA:3.40.1060.10 171 285 1.5E-38 T 05-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 ProSitePatterns PS00450 Aconitase family signature 1. 344 360 - T 05-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 K08M4_RS12930 566c2e913242145af1e8f9406bb0843c 470 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 6 470 59.494 T 05-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 K08M4_RS09705 9afdb5e199b587a6faf6a56bb6c0f6c4 555 SUPERFAMILY SSF48452 141 298 1.19E-14 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS09705 9afdb5e199b587a6faf6a56bb6c0f6c4 555 Pfam PF00072 Response regulator receiver domain 9 124 2.3E-13 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS09705 9afdb5e199b587a6faf6a56bb6c0f6c4 555 Gene3D G3DSA:3.40.50.2300 5 135 6.9E-18 T 05-07-2017 K08M4_RS09705 9afdb5e199b587a6faf6a56bb6c0f6c4 555 PIRSF PIRSF011521 1 539 2.7E-161 T 05-07-2017 IPR014460 Signal transduction response regulator, predicted, VieB K08M4_RS09705 9afdb5e199b587a6faf6a56bb6c0f6c4 555 SUPERFAMILY SSF52172 5 138 2.7E-19 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS09705 9afdb5e199b587a6faf6a56bb6c0f6c4 555 SMART SM00448 6 124 1.5E-13 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS09705 9afdb5e199b587a6faf6a56bb6c0f6c4 555 Gene3D G3DSA:1.25.40.10 355 379 1.4E-15 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS09705 9afdb5e199b587a6faf6a56bb6c0f6c4 555 Gene3D G3DSA:1.25.40.10 137 308 1.4E-15 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS19565 14c84c4537dd814bcd20314574dc9102 285 SUPERFAMILY SSF47616 180 258 2.73E-31 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS19565 14c84c4537dd814bcd20314574dc9102 285 SUPERFAMILY SSF47616 116 151 2.73E-31 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS19565 14c84c4537dd814bcd20314574dc9102 285 Gene3D G3DSA:3.40.30.10 32 129 2.0E-23 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS19565 14c84c4537dd814bcd20314574dc9102 285 SUPERFAMILY SSF52833 39 130 4.24E-15 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS19565 14c84c4537dd814bcd20314574dc9102 285 Pfam PF13410 Glutathione S-transferase, C-terminal domain 176 243 1.3E-8 T 05-07-2017 K08M4_RS19565 14c84c4537dd814bcd20314574dc9102 285 Gene3D G3DSA:1.20.1050.10 130 253 9.0E-39 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS19565 14c84c4537dd814bcd20314574dc9102 285 Pfam PF02798 Glutathione S-transferase, N-terminal domain 55 126 1.8E-6 T 05-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 K08M4_RS17465 4adab402538c3d676f45cca699373927 123 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 29 118 3.8E-25 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS08285 2f58b684f5b127a25f113312b4e1ed6c 369 Pfam PF01814 Hemerythrin HHE cation binding domain 13 128 7.9E-8 T 05-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 K08M4_RS08285 2f58b684f5b127a25f113312b4e1ed6c 369 ProSitePatterns PS00550 Hemerythrin family signature. 59 84 - T 05-07-2017 IPR016131 Haemerythrin, iron-binding site GO:0046872 K08M4_RS08285 2f58b684f5b127a25f113312b4e1ed6c 369 SUPERFAMILY SSF55073 211 365 1.57E-44 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS08285 2f58b684f5b127a25f113312b4e1ed6c 369 Gene3D G3DSA:1.20.120.50 1 131 3.2E-26 T 05-07-2017 IPR012827 Haemerythrin, metal-binding domain GO:0046872 K08M4_RS08285 2f58b684f5b127a25f113312b4e1ed6c 369 SMART SM00267 195 367 6.0E-50 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS08285 2f58b684f5b127a25f113312b4e1ed6c 369 Gene3D G3DSA:3.30.70.270 208 366 5.0E-46 T 05-07-2017 K08M4_RS08285 2f58b684f5b127a25f113312b4e1ed6c 369 Pfam PF00990 Diguanylate cyclase, GGDEF domain 207 362 1.2E-42 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS08285 2f58b684f5b127a25f113312b4e1ed6c 369 SUPERFAMILY SSF47188 1 131 3.79E-26 T 05-07-2017 IPR012827 Haemerythrin, metal-binding domain GO:0046872 K08M4_RS08285 2f58b684f5b127a25f113312b4e1ed6c 369 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 202 365 9.8E-48 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS08285 2f58b684f5b127a25f113312b4e1ed6c 369 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 5 131 6.4E-29 T 05-07-2017 IPR012827 Haemerythrin, metal-binding domain GO:0046872 K08M4_RS08715 4d880661554444f178f4dbf9e41aa747 223 SUPERFAMILY SSF52540 1 217 8.11E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08715 4d880661554444f178f4dbf9e41aa747 223 Gene3D G3DSA:3.40.50.300 1 217 6.0E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08715 4d880661554444f178f4dbf9e41aa747 223 SMART SM00382 30 218 1.3E-10 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS08715 4d880661554444f178f4dbf9e41aa747 223 Pfam PF00005 ABC transporter 21 167 6.8E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS10040 f7d12f21549a2b0561ccc4df13e2eb7d 717 SUPERFAMILY SSF56935 25 717 1.43E-83 T 05-07-2017 K08M4_RS10040 f7d12f21549a2b0561ccc4df13e2eb7d 717 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 151 5.3E-17 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS10040 f7d12f21549a2b0561ccc4df13e2eb7d 717 Gene3D G3DSA:2.170.130.10 26 153 1.0E-25 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS10040 f7d12f21549a2b0561ccc4df13e2eb7d 717 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 50 716 5.7E-77 T 05-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 K08M4_RS10040 f7d12f21549a2b0561ccc4df13e2eb7d 717 Gene3D G3DSA:2.40.170.20 154 717 9.7E-64 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS12815 592ddd2698c900b29269b09ddfc48ecb 338 Pfam PF00814 Glycoprotease family 24 307 1.6E-102 T 05-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 K08M4_RS12815 592ddd2698c900b29269b09ddfc48ecb 338 Gene3D G3DSA:3.30.420.40 1 159 8.6E-48 T 05-07-2017 K08M4_RS12815 592ddd2698c900b29269b09ddfc48ecb 338 SUPERFAMILY SSF53067 101 309 1.77E-45 T 05-07-2017 K08M4_RS12815 592ddd2698c900b29269b09ddfc48ecb 338 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 5 306 1.1E-124 T 05-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 K08M4_RS12815 592ddd2698c900b29269b09ddfc48ecb 338 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 313 1.3E-134 T 05-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 K08M4_RS12815 592ddd2698c900b29269b09ddfc48ecb 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 4.2E-51 T 05-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 K08M4_RS12815 592ddd2698c900b29269b09ddfc48ecb 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 4.2E-51 T 05-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 K08M4_RS12815 592ddd2698c900b29269b09ddfc48ecb 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 263 272 4.2E-51 T 05-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 K08M4_RS12815 592ddd2698c900b29269b09ddfc48ecb 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 4.2E-51 T 05-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 K08M4_RS12815 592ddd2698c900b29269b09ddfc48ecb 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 4.2E-51 T 05-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 K08M4_RS12815 592ddd2698c900b29269b09ddfc48ecb 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 4.2E-51 T 05-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 K08M4_RS12815 592ddd2698c900b29269b09ddfc48ecb 338 SUPERFAMILY SSF53067 3 123 2.85E-30 T 05-07-2017 K08M4_RS12815 592ddd2698c900b29269b09ddfc48ecb 338 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 331 63.287 T 05-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 K08M4_RS12815 592ddd2698c900b29269b09ddfc48ecb 338 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 05-07-2017 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 K08M4_RS09405 f0e198dfb3349427e041f2a46e7f6b3d 264 Pfam PF03649 Uncharacterised protein family (UPF0014) 9 247 7.5E-75 T 05-07-2017 IPR005226 UPF0014 family K08M4_RS21125 312fa0441e132bf147fd35f49bee59ce 228 SUPERFAMILY SSF48150 39 184 1.44E-37 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 K08M4_RS21125 312fa0441e132bf147fd35f49bee59ce 228 Pfam PF03352 Methyladenine glycosylase 47 136 3.3E-14 T 05-07-2017 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 K08M4_RS21125 312fa0441e132bf147fd35f49bee59ce 228 Gene3D G3DSA:1.10.340.30 39 173 9.2E-25 T 05-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 K08M4_RS14020 e60afa0cb3e8b52dc292483989c8650f 224 SUPERFAMILY SSF102712 145 192 5.23E-5 T 05-07-2017 K08M4_RS14020 e60afa0cb3e8b52dc292483989c8650f 224 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 05-07-2017 IPR020891 Uncharacterised protein family UPF0758, conserved site K08M4_RS14020 e60afa0cb3e8b52dc292483989c8650f 224 Pfam PF04002 RadC-like JAB domain 104 222 4.3E-45 T 05-07-2017 IPR025657 RadC-like JAB domain K08M4_RS14020 e60afa0cb3e8b52dc292483989c8650f 224 SUPERFAMILY SSF47781 17 91 1.18E-9 T 05-07-2017 IPR010994 RuvA domain 2-like K08M4_RS14020 e60afa0cb3e8b52dc292483989c8650f 224 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 224 7.1E-77 T 05-07-2017 IPR001405 RadC protein K08M4_RS14020 e60afa0cb3e8b52dc292483989c8650f 224 Gene3D G3DSA:3.40.140.10 101 224 3.5E-51 T 05-07-2017 K08M4_RS16250 099a48d4f23b2446deb856de62ffb52a 190 SUPERFAMILY SSF51645 22 184 5.75E-17 T 05-07-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 K08M4_RS16250 099a48d4f23b2446deb856de62ffb52a 190 Gene3D G3DSA:2.170.170.11 17 184 3.5E-45 T 05-07-2017 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 K08M4_RS11215 c267ca4681e222a866db8463a1730257 185 SUPERFAMILY SSF55194 2 185 1.44E-70 T 05-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 K08M4_RS11215 c267ca4681e222a866db8463a1730257 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 1.7E-74 T 05-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 K08M4_RS11215 c267ca4681e222a866db8463a1730257 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.282 T 05-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 K08M4_RS11215 c267ca4681e222a866db8463a1730257 185 Pfam PF01765 Ribosome recycling factor 20 183 1.3E-61 T 05-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 K08M4_RS11215 c267ca4681e222a866db8463a1730257 185 Gene3D G3DSA:1.10.132.20 67 185 2.5E-44 T 05-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 K08M4_RS18630 9c47eb17cf4a5229cf36164c865f2ea7 399 SUPERFAMILY SSF51735 109 148 7.92E-6 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS18630 9c47eb17cf4a5229cf36164c865f2ea7 399 SUPERFAMILY SSF51735 42 77 7.92E-6 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS18630 9c47eb17cf4a5229cf36164c865f2ea7 399 Pfam PF12242 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3 81 7.8E-33 T 05-07-2017 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS18630 9c47eb17cf4a5229cf36164c865f2ea7 399 Pfam PF12241 Trans-2-enoyl-CoA reductase catalytic region 84 319 2.9E-96 T 05-07-2017 IPR024910 Trans-2-enoyl-CoA reductase catalytic domain, putative KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS18630 9c47eb17cf4a5229cf36164c865f2ea7 399 Pfam PF07055 Enoyl reductase FAD binding domain 326 387 7.7E-23 T 05-07-2017 IPR024906 Enoyl reductase FAD binding domain KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS18630 9c47eb17cf4a5229cf36164c865f2ea7 399 Hamap MF_01838 Trans-2-enoyl-CoA reductase [NADH] [fabV]. 1 395 50.162 T 05-07-2017 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS18630 9c47eb17cf4a5229cf36164c865f2ea7 399 Gene3D G3DSA:3.40.50.720 42 153 3.1E-5 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS15675 96cc477c8e8caa80a2ac0db1bebb955d 273 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 239 4.4E-20 T 05-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 K08M4_RS15675 96cc477c8e8caa80a2ac0db1bebb955d 273 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 267 2.9E-55 T 05-07-2017 IPR000150 Cof protein GO:0016787 K08M4_RS15675 96cc477c8e8caa80a2ac0db1bebb955d 273 Gene3D G3DSA:3.40.50.1000 1 71 2.7E-46 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS15675 96cc477c8e8caa80a2ac0db1bebb955d 273 Gene3D G3DSA:3.40.50.1000 175 271 2.7E-46 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS15675 96cc477c8e8caa80a2ac0db1bebb955d 273 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 267 1.1E-63 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS15675 96cc477c8e8caa80a2ac0db1bebb955d 273 ProSitePatterns PS01229 Hypothetical cof family signature 2. 220 242 - T 05-07-2017 K08M4_RS15675 96cc477c8e8caa80a2ac0db1bebb955d 273 SUPERFAMILY SSF56784 1 271 1.8E-63 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS16845 bf0f559a9971d3e1dc6edf73fe8afd6a 511 Gene3D G3DSA:2.60.120.10 384 496 1.5E-42 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS16845 bf0f559a9971d3e1dc6edf73fe8afd6a 511 SUPERFAMILY SSF53448 1 308 1.54E-65 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS16845 bf0f559a9971d3e1dc6edf73fe8afd6a 511 Gene3D G3DSA:3.90.550.10 2 297 6.0E-97 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS16845 bf0f559a9971d3e1dc6edf73fe8afd6a 511 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 2 495 3.4E-219 T 05-07-2017 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 K08M4_RS16845 bf0f559a9971d3e1dc6edf73fe8afd6a 511 SUPERFAMILY SSF51182 211 495 2.4E-83 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS16845 bf0f559a9971d3e1dc6edf73fe8afd6a 511 Pfam PF01050 Mannose-6-phosphate isomerase 341 491 1.2E-65 T 05-07-2017 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 K08M4_RS16845 bf0f559a9971d3e1dc6edf73fe8afd6a 511 Pfam PF00483 Nucleotidyl transferase 4 312 1.3E-66 T 05-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 K08M4_RS12425 5e511d03338fd16928cb07319e8a5b09 161 Pfam PF03737 Demethylmenaquinone methyltransferase 5 152 2.4E-43 T 05-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein K08M4_RS12425 5e511d03338fd16928cb07319e8a5b09 161 SUPERFAMILY SSF89562 1 156 4.32E-49 T 05-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein K08M4_RS12425 5e511d03338fd16928cb07319e8a5b09 161 TIGRFAM TIGR01935 NOT-MenG: RraA family 5 154 1.9E-67 T 05-07-2017 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 K08M4_RS12425 5e511d03338fd16928cb07319e8a5b09 161 Gene3D G3DSA:3.50.30.40 5 158 1.9E-50 T 05-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein K08M4_RS15735 a9da45fd48c5068c7ceb4a5cdfd8bc6c 580 SMART SM00267 405 572 3.2E-17 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS15735 a9da45fd48c5068c7ceb4a5cdfd8bc6c 580 Gene3D G3DSA:3.30.70.270 420 570 2.4E-22 T 05-07-2017 K08M4_RS15735 a9da45fd48c5068c7ceb4a5cdfd8bc6c 580 SUPERFAMILY SSF55073 422 569 5.57E-22 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS15735 a9da45fd48c5068c7ceb4a5cdfd8bc6c 580 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 416 558 2.0E-17 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS15735 a9da45fd48c5068c7ceb4a5cdfd8bc6c 580 Gene3D G3DSA:3.30.450.20 147 251 1.5E-7 T 05-07-2017 K08M4_RS15735 a9da45fd48c5068c7ceb4a5cdfd8bc6c 580 Pfam PF00990 Diguanylate cyclase, GGDEF domain 419 558 2.0E-17 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS01620 7ad737b7021d1dccc6c1690aacbe1275 150 Pfam PF13673 Acetyltransferase (GNAT) domain 54 149 3.1E-15 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS01620 7ad737b7021d1dccc6c1690aacbe1275 150 Gene3D G3DSA:3.40.630.30 2 148 7.8E-49 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS01620 7ad737b7021d1dccc6c1690aacbe1275 150 SUPERFAMILY SSF55729 1 149 3.12E-35 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS12790 8769a064d1eb145767a2874bef9653ce 267 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 257 1.7E-73 T 05-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 K08M4_RS12790 8769a064d1eb145767a2874bef9653ce 267 Pfam PF02673 Bacitracin resistance protein BacA 6 258 1.7E-75 T 05-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 K08M4_RS12790 8769a064d1eb145767a2874bef9653ce 267 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 264 17.573 T 05-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 K08M4_RS07920 de4529ed7a615e078fa9a2e126e79d5b 221 ProSitePatterns PS01243 Bax inhibitor-1 family signature. 88 118 - T 05-07-2017 IPR006213 Bax inhibitor 1, conserved site GO:0016021|GO:0043066 K08M4_RS07920 de4529ed7a615e078fa9a2e126e79d5b 221 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 19 214 1.7E-41 T 05-07-2017 K08M4_RS18665 b763ab477dffbd7365dcd3257f9bf009 303 Pfam PF00892 EamA-like transporter family 5 149 9.4E-10 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS18665 b763ab477dffbd7365dcd3257f9bf009 303 Pfam PF00892 EamA-like transporter family 162 297 1.1E-14 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS18665 b763ab477dffbd7365dcd3257f9bf009 303 SUPERFAMILY SSF103481 205 300 3.53E-11 T 05-07-2017 K08M4_RS18665 b763ab477dffbd7365dcd3257f9bf009 303 SUPERFAMILY SSF103481 83 153 2.09E-7 T 05-07-2017 K08M4_RS20880 39b6259bcc5e4fe7eec14deb4d2d9814 328 Gene3D G3DSA:3.20.20.120 125 324 1.2E-60 T 05-07-2017 IPR029065 Enolase C-terminal domain-like K08M4_RS20880 39b6259bcc5e4fe7eec14deb4d2d9814 328 SMART SM00922 137 230 1.6E-19 T 05-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal K08M4_RS20880 39b6259bcc5e4fe7eec14deb4d2d9814 328 Pfam PF13378 Enolase C-terminal domain-like 140 326 5.3E-29 T 05-07-2017 IPR029065 Enolase C-terminal domain-like K08M4_RS20880 39b6259bcc5e4fe7eec14deb4d2d9814 328 Gene3D G3DSA:3.30.390.10 1 110 8.5E-39 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS20880 39b6259bcc5e4fe7eec14deb4d2d9814 328 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 12 113 2.7E-9 T 05-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain K08M4_RS20880 39b6259bcc5e4fe7eec14deb4d2d9814 328 SUPERFAMILY SSF51604 125 324 1.27E-53 T 05-07-2017 IPR029065 Enolase C-terminal domain-like K08M4_RS20880 39b6259bcc5e4fe7eec14deb4d2d9814 328 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 05-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 K08M4_RS20880 39b6259bcc5e4fe7eec14deb4d2d9814 328 SUPERFAMILY SSF54826 2 112 2.05E-23 T 05-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 K08M4_RS20605 75edd07c79eb6cbf1fa0b42d622bbff6 468 Gene3D G3DSA:1.10.3860.10 24 448 4.0E-80 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS20605 75edd07c79eb6cbf1fa0b42d622bbff6 468 PRINTS PR00173 Glutamate-aspartate symporter signature 75 95 1.7E-14 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS20605 75edd07c79eb6cbf1fa0b42d622bbff6 468 PRINTS PR00173 Glutamate-aspartate symporter signature 185 207 1.7E-14 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS20605 75edd07c79eb6cbf1fa0b42d622bbff6 468 PRINTS PR00173 Glutamate-aspartate symporter signature 372 391 1.7E-14 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS20605 75edd07c79eb6cbf1fa0b42d622bbff6 468 PRINTS PR00173 Glutamate-aspartate symporter signature 105 130 1.7E-14 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS20605 75edd07c79eb6cbf1fa0b42d622bbff6 468 PRINTS PR00173 Glutamate-aspartate symporter signature 399 419 1.7E-14 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS20605 75edd07c79eb6cbf1fa0b42d622bbff6 468 PRINTS PR00173 Glutamate-aspartate symporter signature 27 47 1.7E-14 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS20605 75edd07c79eb6cbf1fa0b42d622bbff6 468 SUPERFAMILY SSF118215 30 444 1.01E-83 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS20605 75edd07c79eb6cbf1fa0b42d622bbff6 468 Pfam PF00375 Sodium:dicarboxylate symporter family 31 444 1.3E-90 T 05-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 K08M4_RS13685 4f2b9858f5fdea8435da3204860d705b 128 ProDom PD015693 FUMARATE MEMBRANE REDUCTASE D SUBUNIT INNER TRANSMEMBRANE HYDROPHOBIC REDUCTASE POLYPEPTIDE 14 128 1.0E-54 T 05-07-2017 IPR003418 Fumarate reductase, D subunit GO:0006106|GO:0016020 K08M4_RS13685 4f2b9858f5fdea8435da3204860d705b 128 Pfam PF02313 Fumarate reductase subunit D 14 126 1.7E-44 T 05-07-2017 IPR003418 Fumarate reductase, D subunit GO:0006106|GO:0016020 K08M4_RS13685 4f2b9858f5fdea8435da3204860d705b 128 PIRSF PIRSF000179 9 128 1.4E-54 T 05-07-2017 IPR003418 Fumarate reductase, D subunit GO:0006106|GO:0016020 K08M4_RS13685 4f2b9858f5fdea8435da3204860d705b 128 Gene3D G3DSA:1.20.1300.10 11 128 2.4E-53 T 05-07-2017 K08M4_RS13685 4f2b9858f5fdea8435da3204860d705b 128 Hamap MF_00709 Fumarate reductase subunit D [frdD]. 10 128 24.341 T 05-07-2017 IPR003418 Fumarate reductase, D subunit GO:0006106|GO:0016020 K08M4_RS13685 4f2b9858f5fdea8435da3204860d705b 128 SUPERFAMILY SSF81343 10 128 8.94E-49 T 05-07-2017 K08M4_RS11360 7850d8eb9d14e71567c22a055dd670d2 474 SUPERFAMILY SSF55604 10 82 6.15E-21 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS11360 7850d8eb9d14e71567c22a055dd670d2 474 Pfam PF02378 Phosphotransferase system, EIIC 112 404 2.4E-31 T 05-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 K08M4_RS11360 7850d8eb9d14e71567c22a055dd670d2 474 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS11360 7850d8eb9d14e71567c22a055dd670d2 474 Gene3D G3DSA:3.30.1360.60 6 83 2.8E-25 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS11360 7850d8eb9d14e71567c22a055dd670d2 474 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 30 111 1.3E-14 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS11360 7850d8eb9d14e71567c22a055dd670d2 474 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 6 461 5.8E-204 T 05-07-2017 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 K08M4_RS11360 7850d8eb9d14e71567c22a055dd670d2 474 Pfam PF00367 phosphotransferase system, EIIB 11 43 1.3E-14 T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS05255 ee54852340486d142b03734cf3cda7b2 333 Pfam PF09982 Uncharacterized protein conserved in bacteria (DUF2219) 28 330 4.3E-82 T 05-07-2017 IPR018707 Protein of unknown function DUF2219 K08M4_RS05255 ee54852340486d142b03734cf3cda7b2 333 Gene3D G3DSA:2.40.128.140 9 330 3.8E-99 T 05-07-2017 K08M4_RS20305 a16e3d9cdd9097c576815f55e6f878b8 551 Pfam PF12793 Sugar transport-related sRNA regulator N-term 9 112 1.2E-14 T 05-07-2017 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain K08M4_RS20305 a16e3d9cdd9097c576815f55e6f878b8 551 SUPERFAMILY SSF53850 120 546 3.26E-50 T 05-07-2017 K08M4_RS20305 a16e3d9cdd9097c576815f55e6f878b8 551 Gene3D G3DSA:3.90.76.10 133 275 2.6E-26 T 05-07-2017 K08M4_RS20305 a16e3d9cdd9097c576815f55e6f878b8 551 Gene3D G3DSA:3.40.190.10 276 311 5.2E-5 T 05-07-2017 K08M4_RS20305 a16e3d9cdd9097c576815f55e6f878b8 551 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 170 326 4.6E-21 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain K08M4_RS07620 7137e88b5ac1b8fc5bf72b978ab9f7ac 316 SUPERFAMILY SSF52402 173 309 1.59E-22 T 05-07-2017 K08M4_RS07620 7137e88b5ac1b8fc5bf72b978ab9f7ac 316 Gene3D G3DSA:3.40.50.620 142 300 7.9E-24 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS07620 7137e88b5ac1b8fc5bf72b978ab9f7ac 316 Pfam PF00582 Universal stress protein family 178 301 3.0E-15 T 05-07-2017 IPR006016 UspA GO:0006950 K08M4_RS07620 7137e88b5ac1b8fc5bf72b978ab9f7ac 316 Pfam PF00582 Universal stress protein family 4 148 2.2E-14 T 05-07-2017 IPR006016 UspA GO:0006950 K08M4_RS07620 7137e88b5ac1b8fc5bf72b978ab9f7ac 316 SUPERFAMILY SSF52402 4 158 2.51E-26 T 05-07-2017 K08M4_RS07620 7137e88b5ac1b8fc5bf72b978ab9f7ac 316 Gene3D G3DSA:3.40.50.620 3 141 6.7E-21 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS21870 680d5a5c0869daf2be650623232ed965 274 Pfam PF00005 ABC transporter 31 186 3.5E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS21870 680d5a5c0869daf2be650623232ed965 274 Gene3D G3DSA:3.40.50.300 9 259 1.7E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS21870 680d5a5c0869daf2be650623232ed965 274 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS21870 680d5a5c0869daf2be650623232ed965 274 SMART SM00382 39 244 3.0E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS21870 680d5a5c0869daf2be650623232ed965 274 SUPERFAMILY SSF52540 10 258 4.73E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08525 6bfa2fa764c5988dc0ae5d95a6325543 466 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 6 466 7.0E-204 T 05-07-2017 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 K08M4_RS08525 6bfa2fa764c5988dc0ae5d95a6325543 466 SUPERFAMILY SSF55681 97 464 1.79E-93 T 05-07-2017 K08M4_RS08525 6bfa2fa764c5988dc0ae5d95a6325543 466 Gene3D G3DSA:2.40.50.140 15 103 1.6E-16 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS08525 6bfa2fa764c5988dc0ae5d95a6325543 466 Pfam PF01336 OB-fold nucleic acid binding domain 20 99 5.1E-12 T 05-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 K08M4_RS08525 6bfa2fa764c5988dc0ae5d95a6325543 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 220 3.3E-14 T 05-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS08525 6bfa2fa764c5988dc0ae5d95a6325543 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 421 435 3.3E-14 T 05-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS08525 6bfa2fa764c5988dc0ae5d95a6325543 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 381 397 3.3E-14 T 05-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS08525 6bfa2fa764c5988dc0ae5d95a6325543 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 224 237 3.3E-14 T 05-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS08525 6bfa2fa764c5988dc0ae5d95a6325543 466 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 460 6.7E-79 T 05-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS08525 6bfa2fa764c5988dc0ae5d95a6325543 466 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 6 466 45.473 T 05-07-2017 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 K08M4_RS08525 6bfa2fa764c5988dc0ae5d95a6325543 466 Gene3D G3DSA:3.30.930.10 109 462 4.9E-111 T 05-07-2017 K08M4_RS08525 6bfa2fa764c5988dc0ae5d95a6325543 466 SUPERFAMILY SSF50249 16 101 2.57E-17 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS14275 bac796a9cb2405a51c3d8c79e8ec9f9e 311 TIGRFAM TIGR02447 yiiD_Cterm: putative thioesterase domain 164 296 6.8E-46 T 05-07-2017 IPR012660 Thioesterase, putative K08M4_RS14275 bac796a9cb2405a51c3d8c79e8ec9f9e 311 Pfam PF13673 Acetyltransferase (GNAT) domain 54 142 4.0E-9 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS14275 bac796a9cb2405a51c3d8c79e8ec9f9e 311 Gene3D G3DSA:3.40.630.30 5 142 2.4E-24 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS14275 bac796a9cb2405a51c3d8c79e8ec9f9e 311 Pfam PF09500 Putative thioesterase (yiiD_Cterm) 157 296 9.6E-54 T 05-07-2017 IPR012660 Thioesterase, putative K08M4_RS14275 bac796a9cb2405a51c3d8c79e8ec9f9e 311 SUPERFAMILY SSF54637 154 296 4.98E-40 T 05-07-2017 IPR029069 HotDog domain K08M4_RS14275 bac796a9cb2405a51c3d8c79e8ec9f9e 311 Gene3D G3DSA:3.10.129.10 144 297 7.5E-66 T 05-07-2017 IPR029069 HotDog domain K08M4_RS14275 bac796a9cb2405a51c3d8c79e8ec9f9e 311 SUPERFAMILY SSF55729 2 146 6.31E-26 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS15355 7595460469a72d6b318f874438c09447 364 Gene3D G3DSA:2.40.160.10 243 363 1.2E-7 T 05-07-2017 IPR023614 Porin domain K08M4_RS15355 7595460469a72d6b318f874438c09447 364 Gene3D G3DSA:2.40.160.10 34 192 1.2E-7 T 05-07-2017 IPR023614 Porin domain K08M4_RS15355 7595460469a72d6b318f874438c09447 364 Pfam PF16966 Porin-like glycoporin RafY 46 364 9.9E-94 T 05-07-2017 IPR016963 Glycoporin RafY K08M4_RS15355 7595460469a72d6b318f874438c09447 364 SUPERFAMILY SSF56935 28 364 2.5E-14 T 05-07-2017 K08M4_RS18580 f164eb9a88a5bd27f3949598e90f30d6 295 SUPERFAMILY SSF53850 122 289 6.15E-18 T 05-07-2017 K08M4_RS18580 f164eb9a88a5bd27f3949598e90f30d6 295 Gene3D G3DSA:1.10.10.10 5 87 1.2E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS18580 f164eb9a88a5bd27f3949598e90f30d6 295 SUPERFAMILY SSF46785 3 85 1.6E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS18580 f164eb9a88a5bd27f3949598e90f30d6 295 Gene3D G3DSA:3.40.190.10 165 258 8.1E-8 T 05-07-2017 K08M4_RS18580 f164eb9a88a5bd27f3949598e90f30d6 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 3.0E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS18580 f164eb9a88a5bd27f3949598e90f30d6 295 Pfam PF03466 LysR substrate binding domain 123 291 1.5E-14 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS18905 60902ed0a4c2508f8decd966a197cf05 242 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 76 187 1.2E-11 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS18905 60902ed0a4c2508f8decd966a197cf05 242 SUPERFAMILY SSF56784 7 192 4.61E-39 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS18905 60902ed0a4c2508f8decd966a197cf05 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 8.1E-6 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS18905 60902ed0a4c2508f8decd966a197cf05 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 172 8.1E-6 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS18905 60902ed0a4c2508f8decd966a197cf05 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 134 150 8.1E-6 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS18905 60902ed0a4c2508f8decd966a197cf05 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 102 115 8.1E-6 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS18905 60902ed0a4c2508f8decd966a197cf05 242 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 188 1.8E-26 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS18905 60902ed0a4c2508f8decd966a197cf05 242 Gene3D G3DSA:3.40.50.1000 93 192 1.1E-30 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS18905 60902ed0a4c2508f8decd966a197cf05 242 Gene3D G3DSA:3.40.50.1000 3 20 1.1E-30 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS00280 b4f727f68dafd3c0f64e385fb52cfe87 436 Gene3D G3DSA:3.40.50.300 224 385 1.0E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00280 b4f727f68dafd3c0f64e385fb52cfe87 436 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 163 171 - T 05-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site K08M4_RS00280 b4f727f68dafd3c0f64e385fb52cfe87 436 Pfam PF00271 Helicase conserved C-terminal domain 244 351 9.7E-30 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS00280 b4f727f68dafd3c0f64e385fb52cfe87 436 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 8 389 50.038 T 05-07-2017 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 K08M4_RS00280 b4f727f68dafd3c0f64e385fb52cfe87 436 SMART SM00490 270 351 1.2E-31 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS00280 b4f727f68dafd3c0f64e385fb52cfe87 436 SUPERFAMILY SSF52540 84 363 6.29E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00280 b4f727f68dafd3c0f64e385fb52cfe87 436 SMART SM00487 28 234 4.0E-57 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS00280 b4f727f68dafd3c0f64e385fb52cfe87 436 Gene3D G3DSA:3.40.50.300 7 223 4.8E-74 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00280 b4f727f68dafd3c0f64e385fb52cfe87 436 Pfam PF00270 DEAD/DEAH box helicase 33 207 2.2E-45 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS11885 e6e2676bfc76334cbd3e8b7877505cc6 171 Gene3D G3DSA:1.10.287.110 1 72 1.5E-25 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS11885 e6e2676bfc76334cbd3e8b7877505cc6 171 SUPERFAMILY SSF47144 78 169 8.24E-25 T 05-07-2017 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020 K08M4_RS11885 e6e2676bfc76334cbd3e8b7877505cc6 171 SUPERFAMILY SSF46565 1 74 3.66E-17 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS11885 e6e2676bfc76334cbd3e8b7877505cc6 171 SMART SM00271 1 66 8.9E-10 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS11885 e6e2676bfc76334cbd3e8b7877505cc6 171 Gene3D G3DSA:1.20.1280.20 81 170 8.8E-31 T 05-07-2017 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020 K08M4_RS11885 e6e2676bfc76334cbd3e8b7877505cc6 171 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 13 168 9.9E-41 T 05-07-2017 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 Reactome: R-HSA-1268020 K08M4_RS11885 e6e2676bfc76334cbd3e8b7877505cc6 171 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 1 170 25.32 T 05-07-2017 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 Reactome: R-HSA-1268020 K08M4_RS11885 e6e2676bfc76334cbd3e8b7877505cc6 171 Pfam PF00226 DnaJ domain 3 70 2.2E-7 T 05-07-2017 IPR001623 DnaJ domain K08M4_RS11885 e6e2676bfc76334cbd3e8b7877505cc6 171 Pfam PF07743 HSCB C-terminal oligomerisation domain 87 163 1.6E-19 T 05-07-2017 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020 K08M4_RS06940 17b241049de2928c4c30afeae693eea5 47 Pfam PF10013 Uncharacterized protein conserved in bacteria (DUF2256) 3 42 4.3E-22 T 05-07-2017 IPR017136 Uncharacterised conserved protein UCP037205 K08M4_RS06940 17b241049de2928c4c30afeae693eea5 47 PIRSF PIRSF037205 1 47 6.1E-25 T 05-07-2017 IPR017136 Uncharacterised conserved protein UCP037205 K08M4_RS07830 7a6a80136d5cdd963491f753ff38726a 664 Gene3D G3DSA:3.30.750.44 178 251 1.0E-4 T 05-07-2017 K08M4_RS07830 7a6a80136d5cdd963491f753ff38726a 664 SMART SM00228 246 323 1.8E-7 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS07830 7a6a80136d5cdd963491f753ff38726a 664 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 530 663 1.8E-37 T 05-07-2017 IPR020992 Tail specific protease, C-terminal K08M4_RS07830 7a6a80136d5cdd963491f753ff38726a 664 SUPERFAMILY SSF52096 350 538 1.82E-73 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS07830 7a6a80136d5cdd963491f753ff38726a 664 SUPERFAMILY SSF52096 166 264 1.82E-73 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS07830 7a6a80136d5cdd963491f753ff38726a 664 SMART SM00245 326 527 1.2E-69 T 05-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 K08M4_RS07830 7a6a80136d5cdd963491f753ff38726a 664 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 239 320 8.5E-13 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS07830 7a6a80136d5cdd963491f753ff38726a 664 Gene3D G3DSA:2.30.42.10 252 335 2.9E-20 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS07830 7a6a80136d5cdd963491f753ff38726a 664 Gene3D G3DSA:3.90.226.10 641 663 6.4E-65 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS07830 7a6a80136d5cdd963491f753ff38726a 664 Gene3D G3DSA:3.90.226.10 336 529 6.4E-65 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS07830 7a6a80136d5cdd963491f753ff38726a 664 SUPERFAMILY SSF50156 237 323 1.48E-10 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS07830 7a6a80136d5cdd963491f753ff38726a 664 Pfam PF03572 Peptidase family S41 356 525 2.5E-52 T 05-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 K08M4_RS07830 7a6a80136d5cdd963491f753ff38726a 664 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 199 547 3.4E-115 T 05-07-2017 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 K08M4_RS07830 7a6a80136d5cdd963491f753ff38726a 664 Pfam PF08180 B melanoma antigen family 9 36 1.0E-12 T 05-07-2017 IPR012530 B melanoma antigen K08M4_RS11870 5083f374750aee0d71209b2d6b668082 66 Pfam PF04384 Iron-sulphur cluster assembly 3 65 8.8E-32 T 05-07-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 K08M4_RS11870 5083f374750aee0d71209b2d6b668082 66 Gene3D G3DSA:1.10.10.600 1 66 1.1E-33 T 05-07-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 K08M4_RS11870 5083f374750aee0d71209b2d6b668082 66 PIRSF PIRSF039003 3 66 6.4E-33 T 05-07-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 K08M4_RS11870 5083f374750aee0d71209b2d6b668082 66 SUPERFAMILY SSF140319 2 64 6.54E-28 T 05-07-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 K08M4_RS11870 5083f374750aee0d71209b2d6b668082 66 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 4 66 5.0E-34 T 05-07-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 K08M4_RS12215 bff88525e6f6ae4bbf16c050c3441a18 556 SUPERFAMILY SSF55781 227 351 4.77E-8 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS12215 bff88525e6f6ae4bbf16c050c3441a18 556 Gene3D G3DSA:3.30.450.40 301 366 0.001 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS12215 bff88525e6f6ae4bbf16c050c3441a18 556 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 227 350 1.3E-6 T 05-07-2017 K08M4_RS12215 bff88525e6f6ae4bbf16c050c3441a18 556 Pfam PF07694 5TMR of 5TMR-LYT 26 194 8.6E-61 T 05-07-2017 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 K08M4_RS12215 bff88525e6f6ae4bbf16c050c3441a18 556 Pfam PF06580 Histidine kinase 366 444 4.7E-26 T 05-07-2017 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 K08M4_RS12215 bff88525e6f6ae4bbf16c050c3441a18 556 Gene3D G3DSA:3.30.565.10 414 554 8.2E-12 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS12215 bff88525e6f6ae4bbf16c050c3441a18 556 SUPERFAMILY SSF55874 429 554 2.01E-11 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS12160 a2e1b09e42d620e70da578f775a85cb5 649 SUPERFAMILY SSF53955 485 640 1.5E-46 T 05-07-2017 IPR023346 Lysozyme-like domain K08M4_RS12160 a2e1b09e42d620e70da578f775a85cb5 649 Pfam PF14718 Soluble lytic murein transglycosylase L domain 413 477 2.7E-20 T 05-07-2017 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 K08M4_RS12160 a2e1b09e42d620e70da578f775a85cb5 649 SUPERFAMILY SSF48435 34 482 1.7E-124 T 05-07-2017 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 K08M4_RS12160 a2e1b09e42d620e70da578f775a85cb5 649 Gene3D G3DSA:1.10.530.10 480 640 1.3E-47 T 05-07-2017 K08M4_RS12160 a2e1b09e42d620e70da578f775a85cb5 649 Gene3D G3DSA:1.10.1240.20 411 477 9.5E-25 T 05-07-2017 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 K08M4_RS12160 a2e1b09e42d620e70da578f775a85cb5 649 Gene3D G3DSA:1.25.20.10 35 395 8.6E-104 T 05-07-2017 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 K08M4_RS12160 a2e1b09e42d620e70da578f775a85cb5 649 Pfam PF01464 Transglycosylase SLT domain 490 600 8.0E-28 T 05-07-2017 IPR008258 Transglycosylase SLT domain 1 K08M4_RS18235 c1abb1217aedd972b136d900461d813a 458 Pfam PF01618 MotA/TolQ/ExbB proton channel family 311 430 7.7E-31 T 05-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 K08M4_RS18235 c1abb1217aedd972b136d900461d813a 458 PIRSF PIRSF037714 1 452 2.0E-151 T 05-07-2017 IPR017270 Putative MotA/TolQ/ExbB family protein K08M4_RS18080 c1abb1217aedd972b136d900461d813a 458 Pfam PF01618 MotA/TolQ/ExbB proton channel family 311 430 7.7E-31 T 05-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 K08M4_RS18080 c1abb1217aedd972b136d900461d813a 458 PIRSF PIRSF037714 1 452 2.0E-151 T 05-07-2017 IPR017270 Putative MotA/TolQ/ExbB family protein K08M4_RS13245 e4d4470a11b1e40528669900af5eeaa3 100 Pfam PF13592 Winged helix-turn helix 37 94 5.2E-14 T 05-07-2017 IPR025959 Winged helix-turn helix domain K08M4_RS05660 7d0ca695daa21f0a05a966c04047d85c 245 Pfam PF01738 Dienelactone hydrolase family 40 242 2.7E-36 T 05-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 K08M4_RS05660 7d0ca695daa21f0a05a966c04047d85c 245 Gene3D G3DSA:3.40.50.1820 20 241 8.2E-40 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS05660 7d0ca695daa21f0a05a966c04047d85c 245 SUPERFAMILY SSF53474 21 240 9.78E-33 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS17630 ecde9771b5af4b964cceb05e35586a9b 528 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 37 519 3.9E-145 T 05-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 K08M4_RS12005 58c0ae2add22989dd9d51bbdb12ddde4 272 Gene3D G3DSA:3.40.50.300 18 263 4.5E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12005 58c0ae2add22989dd9d51bbdb12ddde4 272 SMART SM00382 50 252 1.8E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS12005 58c0ae2add22989dd9d51bbdb12ddde4 272 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS12005 58c0ae2add22989dd9d51bbdb12ddde4 272 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 26 272 7.2E-123 T 05-07-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 K08M4_RS12005 58c0ae2add22989dd9d51bbdb12ddde4 272 Pfam PF00005 ABC transporter 41 197 2.1E-32 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS12005 58c0ae2add22989dd9d51bbdb12ddde4 272 SUPERFAMILY SSF52540 21 258 1.3E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12635 a6ea402574a469f489d7419c1cb5c92e 196 SUPERFAMILY SSF53697 1 191 1.62E-56 T 05-07-2017 K08M4_RS12635 a6ea402574a469f489d7419c1cb5c92e 196 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 190 34.207 T 05-07-2017 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 K08M4_RS12635 a6ea402574a469f489d7419c1cb5c92e 196 Gene3D G3DSA:3.40.50.10490 2 191 1.9E-58 T 05-07-2017 K08M4_RS12635 a6ea402574a469f489d7419c1cb5c92e 196 Pfam PF13580 SIS domain 9 144 9.9E-34 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 3 469 1.3E-193 T 05-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 Gene3D G3DSA:1.10.10.350 366 465 3.3E-27 T 05-07-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 1.5E-27 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 PRINTS PR00987 Glutamyl-tRNA synthetase signature 182 192 1.5E-27 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 1.5E-27 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 1.5E-27 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 PRINTS PR00987 Glutamyl-tRNA synthetase signature 198 206 1.5E-27 T 05-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 Gene3D G3DSA:3.40.50.620 184 233 1.4E-54 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 Gene3D G3DSA:3.40.50.620 2 67 1.4E-54 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 Gene3D G3DSA:3.90.800.10 68 183 5.9E-35 T 05-07-2017 K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 SUPERFAMILY SSF48163 302 465 2.75E-44 T 05-07-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 Gene3D G3DSA:1.10.1160.10 236 316 3.4E-35 T 05-07-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 SUPERFAMILY SSF52374 3 301 1.26E-107 T 05-07-2017 K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 3 465 33.596 T 05-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 308 2.5E-114 T 05-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 K08M4_RS03890 4cea7e842d0c4b5c3ca2107824c78a60 475 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 05-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 K08M4_RS17385 275e0a87a2afd4b32649581fad383e89 253 TIGRFAM TIGR03950 sidero_Fe_reduc: siderophore ferric iron reductase, AHA_1954 family 21 244 4.5E-89 T 05-07-2017 IPR023998 Siderophore ferric iron reductase, AHA1954 family K08M4_RS11650 0d2b83bbe5d53a7a7fe6078a8a5736ca 520 Pfam PF03806 AbgT putative transporter family 20 518 1.1E-210 T 05-07-2017 IPR004697 p-aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 K08M4_RS04760 53b3ad8582307fe8bd93bed7629ff91f 75 Hamap MF_00816 UPF0352 protein YejL [yejL]. 1 71 22.704 T 05-07-2017 IPR009857 Uncharacterised protein family UPF0352 K08M4_RS04760 53b3ad8582307fe8bd93bed7629ff91f 75 SUPERFAMILY SSF158651 1 75 7.98E-29 T 05-07-2017 K08M4_RS04760 53b3ad8582307fe8bd93bed7629ff91f 75 ProDom PD027794 UPF0352 YEJL NTHI1007 CPS_2611 VF1649 VV1166 HD1515 VP2129 YPO1261/Y2923/YP0880 ECA2748 1 69 1.0E-26 T 05-07-2017 IPR009857 Uncharacterised protein family UPF0352 K08M4_RS04760 53b3ad8582307fe8bd93bed7629ff91f 75 Gene3D G3DSA:1.10.3390.10 1 75 4.7E-33 T 05-07-2017 IPR023202 YejL-like domain K08M4_RS04760 53b3ad8582307fe8bd93bed7629ff91f 75 Pfam PF07208 Protein of unknown function (DUF1414) 26 69 1.3E-20 T 05-07-2017 IPR009857 Uncharacterised protein family UPF0352 K08M4_RS04760 53b3ad8582307fe8bd93bed7629ff91f 75 PIRSF PIRSF006188 1 72 2.1E-34 T 05-07-2017 IPR009857 Uncharacterised protein family UPF0352 K08M4_RS16375 36150fb566c5b941a897690c4c3b27ef 176 Gene3D G3DSA:2.30.110.10 18 151 8.9E-47 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 K08M4_RS16375 36150fb566c5b941a897690c4c3b27ef 176 SUPERFAMILY SSF50475 12 162 1.31E-35 T 05-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 K08M4_RS16375 36150fb566c5b941a897690c4c3b27ef 176 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 15 105 1.2E-18 T 05-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 K08M4_RS16375 36150fb566c5b941a897690c4c3b27ef 176 TIGRFAM TIGR04110 heme_HutZ: heme utilization protein HutZ 4 171 1.6E-92 T 05-07-2017 IPR014419 Heme utilization protein with pyridoxamine 5'-phosphate domain K08M4_RS16375 36150fb566c5b941a897690c4c3b27ef 176 PIRSF PIRSF004633 1 176 7.6E-80 T 05-07-2017 IPR014419 Heme utilization protein with pyridoxamine 5'-phosphate domain K08M4_RS08235 073a4bfd42233abd9c752ff689cec649 290 Gene3D G3DSA:3.40.1090.10 7 247 1.7E-11 T 05-07-2017 K08M4_RS08235 073a4bfd42233abd9c752ff689cec649 290 Pfam PF01734 Patatin-like phospholipase 7 164 1.5E-20 T 05-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 K08M4_RS08235 073a4bfd42233abd9c752ff689cec649 290 SUPERFAMILY SSF52151 3 280 1.6E-51 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 K08M4_RS16770 0223e012509ccbe0200d62fecc3a817b 223 Pfam PF11769 Protein of unknown function (DUF3313) 15 213 1.2E-45 T 05-07-2017 IPR021747 Protein of unknown function DUF3313 K08M4_RS04105 76dea4cb937f5c6b97473c0258769e49 388 SUPERFAMILY SSF64518 1 387 4.45E-98 T 05-07-2017 K08M4_RS04105 76dea4cb937f5c6b97473c0258769e49 388 Pfam PF07196 Flagellin hook IN motif 194 249 5.3E-12 T 05-07-2017 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 K08M4_RS04105 76dea4cb937f5c6b97473c0258769e49 388 PRINTS PR00207 Flagellin signature 37 54 3.5E-27 T 05-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 K08M4_RS04105 76dea4cb937f5c6b97473c0258769e49 388 PRINTS PR00207 Flagellin signature 76 95 3.5E-27 T 05-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 K08M4_RS04105 76dea4cb937f5c6b97473c0258769e49 388 PRINTS PR00207 Flagellin signature 111 134 3.5E-27 T 05-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 K08M4_RS04105 76dea4cb937f5c6b97473c0258769e49 388 Pfam PF00700 Bacterial flagellin C-terminal helical region 303 387 1.9E-26 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS04105 76dea4cb937f5c6b97473c0258769e49 388 Gene3D G3DSA:1.20.1330.10 55 171 6.3E-62 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS04105 76dea4cb937f5c6b97473c0258769e49 388 Gene3D G3DSA:1.20.1330.10 290 343 6.3E-62 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS04105 76dea4cb937f5c6b97473c0258769e49 388 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 1.5E-41 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS03070 e4790dc28f9f79a5e0279ca2661dadab 98 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 98 3.0E-41 T 05-07-2017 IPR001890 RNA-binding, CRM domain GO:0003723 K08M4_RS03070 e4790dc28f9f79a5e0279ca2661dadab 98 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 86 2.2E-19 T 05-07-2017 IPR001890 RNA-binding, CRM domain GO:0003723 K08M4_RS03070 e4790dc28f9f79a5e0279ca2661dadab 98 SMART SM01103 3 86 1.6E-40 T 05-07-2017 IPR001890 RNA-binding, CRM domain GO:0003723 K08M4_RS03070 e4790dc28f9f79a5e0279ca2661dadab 98 SUPERFAMILY SSF75471 1 93 3.01E-28 T 05-07-2017 IPR001890 RNA-binding, CRM domain GO:0003723 K08M4_RS03070 e4790dc28f9f79a5e0279ca2661dadab 98 Gene3D G3DSA:3.30.110.60 1 95 1.6E-30 T 05-07-2017 IPR001890 RNA-binding, CRM domain GO:0003723 K08M4_RS03070 e4790dc28f9f79a5e0279ca2661dadab 98 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 3 97 1.6E-35 T 05-07-2017 IPR017924 RNA-binding protein YhbY GO:0003723 K08M4_RS16050 ea1acc94b000eb250474cfa92629ac65 394 PRINTS PR00181 Maltose binding protein signature 148 167 2.2E-58 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS16050 ea1acc94b000eb250474cfa92629ac65 394 PRINTS PR00181 Maltose binding protein signature 355 374 2.2E-58 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS16050 ea1acc94b000eb250474cfa92629ac65 394 PRINTS PR00181 Maltose binding protein signature 67 85 2.2E-58 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS16050 ea1acc94b000eb250474cfa92629ac65 394 PRINTS PR00181 Maltose binding protein signature 231 250 2.2E-58 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS16050 ea1acc94b000eb250474cfa92629ac65 394 PRINTS PR00181 Maltose binding protein signature 33 51 2.2E-58 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS16050 ea1acc94b000eb250474cfa92629ac65 394 PRINTS PR00181 Maltose binding protein signature 297 318 2.2E-58 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS16050 ea1acc94b000eb250474cfa92629ac65 394 PRINTS PR00181 Maltose binding protein signature 127 146 2.2E-58 T 05-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 K08M4_RS16050 ea1acc94b000eb250474cfa92629ac65 394 Gene3D G3DSA:3.40.190.10 28 148 2.9E-21 T 05-07-2017 K08M4_RS16050 ea1acc94b000eb250474cfa92629ac65 394 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 130 147 - T 05-07-2017 IPR006061 Solute-binding family 1, conserved site GO:0005215|GO:0006810 K08M4_RS16050 ea1acc94b000eb250474cfa92629ac65 394 Pfam PF13416 Bacterial extracellular solute-binding protein 47 324 6.0E-41 T 05-07-2017 K08M4_RS16050 ea1acc94b000eb250474cfa92629ac65 394 Gene3D G3DSA:3.40.190.10 149 319 2.1E-49 T 05-07-2017 K08M4_RS16050 ea1acc94b000eb250474cfa92629ac65 394 SUPERFAMILY SSF53850 25 393 4.95E-83 T 05-07-2017 K08M4_RS07325 7f2a2591b5eba28c69a2ad8e8001b05b 366 Pfam PF13439 Glycosyltransferase Family 4 22 179 1.2E-13 T 05-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 K08M4_RS07325 7f2a2591b5eba28c69a2ad8e8001b05b 366 Gene3D G3DSA:3.40.50.2000 168 310 5.2E-27 T 05-07-2017 K08M4_RS07325 7f2a2591b5eba28c69a2ad8e8001b05b 366 Pfam PF00534 Glycosyl transferases group 1 187 326 7.9E-31 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 K08M4_RS07325 7f2a2591b5eba28c69a2ad8e8001b05b 366 SUPERFAMILY SSF53756 11 359 1.95E-63 T 05-07-2017 K08M4_RS16005 ec105f09133676a52ef801bbd3b047a4 616 Pfam PF00515 Tetratricopeptide repeat 397 429 4.3E-8 T 05-07-2017 IPR001440 Tetratricopeptide repeat 1 GO:0005515 K08M4_RS16005 ec105f09133676a52ef801bbd3b047a4 616 SMART SM00028 396 429 3.0E-6 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS16005 ec105f09133676a52ef801bbd3b047a4 616 Gene3D G3DSA:1.25.40.10 372 447 1.5E-10 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS16005 ec105f09133676a52ef801bbd3b047a4 616 Pfam PF13519 von Willebrand factor type A domain 88 194 6.4E-11 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS16005 ec105f09133676a52ef801bbd3b047a4 616 SUPERFAMILY SSF48452 351 444 7.03E-12 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS16005 ec105f09133676a52ef801bbd3b047a4 616 SUPERFAMILY SSF53300 88 278 5.56E-14 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS09810 aa15a04eacd12cc30e91cd9c3490fab8 776 Gene3D G3DSA:3.60.15.10 506 737 1.3E-29 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS09810 aa15a04eacd12cc30e91cd9c3490fab8 776 SUPERFAMILY SSF56281 507 762 1.49E-42 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS09810 aa15a04eacd12cc30e91cd9c3490fab8 776 SMART SM00849 519 713 8.4E-10 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS09810 aa15a04eacd12cc30e91cd9c3490fab8 776 Pfam PF03772 Competence protein 205 479 1.4E-50 T 05-07-2017 IPR004477 ComEC/Rec2-related protein K08M4_RS09810 aa15a04eacd12cc30e91cd9c3490fab8 776 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 116 742 4.2E-118 T 05-07-2017 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 K08M4_RS09810 aa15a04eacd12cc30e91cd9c3490fab8 776 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 227 405 1.3E-26 T 05-07-2017 IPR004477 ComEC/Rec2-related protein K08M4_RS09810 aa15a04eacd12cc30e91cd9c3490fab8 776 Pfam PF00753 Metallo-beta-lactamase superfamily 517 704 1.4E-10 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS09985 b04372d1b009db54a83de699546490e6 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 7.8E-16 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS09985 b04372d1b009db54a83de699546490e6 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.4E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS09985 b04372d1b009db54a83de699546490e6 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 2.4E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS09985 b04372d1b009db54a83de699546490e6 204 Gene3D G3DSA:1.10.357.10 6 200 1.5E-44 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS09985 b04372d1b009db54a83de699546490e6 204 SUPERFAMILY SSF46689 5 65 6.48E-19 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS13160 970884c752788fa0e68a1d1c6f093a60 574 SUPERFAMILY SSF160246 2 145 2.88E-40 T 05-07-2017 K08M4_RS13160 970884c752788fa0e68a1d1c6f093a60 574 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 381 395 - T 05-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 K08M4_RS13160 970884c752788fa0e68a1d1c6f093a60 574 SMART SM00382 314 435 3.3E-4 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS13160 970884c752788fa0e68a1d1c6f093a60 574 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 42 148 2.0E-22 T 05-07-2017 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 K08M4_RS13160 970884c752788fa0e68a1d1c6f093a60 574 Pfam PF00437 Type II/IV secretion system protein 191 453 1.1E-73 T 05-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 K08M4_RS13160 970884c752788fa0e68a1d1c6f093a60 574 Gene3D G3DSA:3.30.450.90 159 286 2.8E-47 T 05-07-2017 K08M4_RS13160 970884c752788fa0e68a1d1c6f093a60 574 Gene3D G3DSA:3.40.50.300 292 559 5.2E-88 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13160 970884c752788fa0e68a1d1c6f093a60 574 SUPERFAMILY SSF52540 174 559 3.38E-91 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 Gene3D G3DSA:3.40.50.740 371 394 5.7E-61 T 05-07-2017 K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 Gene3D G3DSA:3.40.50.740 118 189 5.7E-61 T 05-07-2017 K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 Gene3D G3DSA:3.40.50.740 446 616 5.7E-61 T 05-07-2017 K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 SMART SM00926 61 115 3.9E-16 T 05-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 SUPERFAMILY SSF53706 60 649 6.54E-198 T 05-07-2017 K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 Pfam PF00384 Molybdopterin oxidoreductase 118 569 1.8E-52 T 05-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 Gene3D G3DSA:2.20.25.90 59 115 8.5E-18 T 05-07-2017 K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 19 43 5.5E-4 T 05-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 Pfam PF01568 Molydopterin dinucleotide binding domain 818 944 5.4E-20 T 05-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 62 112 1.8E-11 T 05-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 66 83 - T 05-07-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 Gene3D G3DSA:3.40.228.10 191 370 3.7E-61 T 05-07-2017 K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 Gene3D G3DSA:2.40.40.20 812 951 5.8E-57 T 05-07-2017 K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 Gene3D G3DSA:2.40.40.20 768 779 5.8E-57 T 05-07-2017 K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 Gene3D G3DSA:2.40.40.20 641 674 5.8E-57 T 05-07-2017 K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 SUPERFAMILY SSF50692 752 782 3.11E-38 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain K08M4_RS07540 3a0c7ab1e6944f2599557ae801b33a45 951 SUPERFAMILY SSF50692 813 951 3.11E-38 T 05-07-2017 IPR009010 Aspartate decarboxylase-like domain K08M4_RS07840 7d1c298bb89e400e001d1f635413bf07 163 Pfam PF13185 GAF domain 29 151 1.7E-8 T 05-07-2017 IPR003018 GAF domain GO:0005515 K08M4_RS07840 7d1c298bb89e400e001d1f635413bf07 163 Gene3D G3DSA:3.30.450.40 4 157 1.4E-46 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS07840 7d1c298bb89e400e001d1f635413bf07 163 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 95 112 - T 05-07-2017 IPR000614 Free Met sulfoxide reductase conserved site K08M4_RS07840 7d1c298bb89e400e001d1f635413bf07 163 SUPERFAMILY SSF55781 3 151 4.58E-37 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS05120 bb24c40b0f27866bd26069ee7e06781e 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 188 2.7E-6 T 05-07-2017 K08M4_RS05120 bb24c40b0f27866bd26069ee7e06781e 245 Gene3D G3DSA:3.40.50.720 1 244 8.0E-91 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS05120 bb24c40b0f27866bd26069ee7e06781e 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 5.1E-17 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05120 bb24c40b0f27866bd26069ee7e06781e 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 5.1E-17 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05120 bb24c40b0f27866bd26069ee7e06781e 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 5.1E-17 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05120 bb24c40b0f27866bd26069ee7e06781e 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 1.2E-67 T 05-07-2017 K08M4_RS05120 bb24c40b0f27866bd26069ee7e06781e 245 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 243 4.6E-100 T 05-07-2017 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 K08M4_RS05120 bb24c40b0f27866bd26069ee7e06781e 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 K08M4_RS05120 bb24c40b0f27866bd26069ee7e06781e 245 SUPERFAMILY SSF51735 5 244 4.97E-88 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS05120 bb24c40b0f27866bd26069ee7e06781e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 5.2E-53 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05120 bb24c40b0f27866bd26069ee7e06781e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 5.2E-53 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05120 bb24c40b0f27866bd26069ee7e06781e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.2E-53 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05120 bb24c40b0f27866bd26069ee7e06781e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.2E-53 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05120 bb24c40b0f27866bd26069ee7e06781e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 5.2E-53 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS05120 bb24c40b0f27866bd26069ee7e06781e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 5.2E-53 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS03655 3365744d02dd3247b527e9e8fc2a0231 296 Pfam PF00571 CBS domain 73 130 1.6E-8 T 05-07-2017 IPR000644 CBS domain K08M4_RS03655 3365744d02dd3247b527e9e8fc2a0231 296 Pfam PF00571 CBS domain 143 193 2.3E-6 T 05-07-2017 IPR000644 CBS domain K08M4_RS03655 3365744d02dd3247b527e9e8fc2a0231 296 SUPERFAMILY SSF54631 63 204 4.64E-33 T 05-07-2017 K08M4_RS03655 3365744d02dd3247b527e9e8fc2a0231 296 SMART SM00116 145 193 0.47 T 05-07-2017 IPR000644 CBS domain K08M4_RS03655 3365744d02dd3247b527e9e8fc2a0231 296 SMART SM00116 82 131 0.0024 T 05-07-2017 IPR000644 CBS domain K08M4_RS03655 3365744d02dd3247b527e9e8fc2a0231 296 SMART SM01091 209 287 8.5E-31 T 05-07-2017 IPR005170 Transporter-associated domain K08M4_RS03655 3365744d02dd3247b527e9e8fc2a0231 296 SUPERFAMILY SSF56176 204 286 1.2E-23 T 05-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 K08M4_RS03655 3365744d02dd3247b527e9e8fc2a0231 296 Pfam PF03471 Transporter associated domain 210 285 2.4E-21 T 05-07-2017 IPR005170 Transporter-associated domain K08M4_RS03655 3365744d02dd3247b527e9e8fc2a0231 296 Gene3D G3DSA:3.30.465.10 202 288 4.9E-30 T 05-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 K08M4_RS03655 3365744d02dd3247b527e9e8fc2a0231 296 Gene3D G3DSA:3.10.580.10 59 201 7.1E-24 T 05-07-2017 K08M4_RS21545 091d6862385cfd92b50f435512612e63 206 SUPERFAMILY SSF88697 23 202 3.98E-31 T 05-07-2017 IPR015947 PUA-like domain K08M4_RS05100 66a666361caeda19423a6de37dcc33a8 56 Pfam PF01783 Ribosomal L32p protein family 2 56 4.0E-19 T 05-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS05100 66a666361caeda19423a6de37dcc33a8 56 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 16.844 T 05-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS05100 66a666361caeda19423a6de37dcc33a8 56 SUPERFAMILY SSF57829 2 55 7.94E-17 T 05-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 K08M4_RS05100 66a666361caeda19423a6de37dcc33a8 56 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 1.4E-18 T 05-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS19580 8071aa216b0abb33e0d4e878968f6beb 412 Gene3D G3DSA:1.20.1250.20 9 195 9.3E-25 T 05-07-2017 K08M4_RS19580 8071aa216b0abb33e0d4e878968f6beb 412 SUPERFAMILY SSF103473 10 398 1.83E-57 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS19580 8071aa216b0abb33e0d4e878968f6beb 412 Pfam PF07690 Major Facilitator Superfamily 15 295 1.1E-30 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS19580 8071aa216b0abb33e0d4e878968f6beb 412 Gene3D G3DSA:1.20.1250.20 220 403 5.8E-18 T 05-07-2017 K08M4_RS10975 ff6461c3a0b253781ad2813850cdd7ac 95 PIRSF PIRSF037266 1 94 2.5E-41 T 05-07-2017 IPR017162 Uncharacterised conserved protein UCP037266 K08M4_RS10975 ff6461c3a0b253781ad2813850cdd7ac 95 Pfam PF09904 Winged helix-turn helix 4 90 2.6E-37 T 05-07-2017 IPR017162 Uncharacterised conserved protein UCP037266 K08M4_RS19045 92eb58e717b9db5b99856a084ef9c6e4 460 PIRSF PIRSF006603 12 457 4.3E-67 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS19045 92eb58e717b9db5b99856a084ef9c6e4 460 Pfam PF01554 MatE 21 180 2.3E-33 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS19045 92eb58e717b9db5b99856a084ef9c6e4 460 Pfam PF01554 MatE 246 406 1.5E-34 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS19045 92eb58e717b9db5b99856a084ef9c6e4 460 TIGRFAM TIGR00797 matE: MATE efflux family protein 21 424 4.9E-100 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS09385 d32cebf61ebd2fa25b42626dfd4f9de4 404 Pfam PF11449 Putative, 10TM heavy-metal exporter 41 402 3.2E-158 T 05-07-2017 IPR021552 Putative, 10TM heavy-metal exporter K08M4_RS14385 3581b8f358934f2c5f1aedc45aac0e08 253 Gene3D G3DSA:3.20.20.140 1 253 5.1E-79 T 05-07-2017 K08M4_RS14385 3581b8f358934f2c5f1aedc45aac0e08 253 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 252 4.1E-73 T 05-07-2017 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 K08M4_RS14385 3581b8f358934f2c5f1aedc45aac0e08 253 PIRSF PIRSF005902 1 253 2.0E-71 T 05-07-2017 IPR001130 TatD family GO:0016788 K08M4_RS14385 3581b8f358934f2c5f1aedc45aac0e08 253 SUPERFAMILY SSF51556 1 253 1.31E-79 T 05-07-2017 IPR032466 Metal-dependent hydrolase K08M4_RS14385 3581b8f358934f2c5f1aedc45aac0e08 253 Pfam PF01026 TatD related DNase 2 251 4.7E-66 T 05-07-2017 IPR001130 TatD family GO:0016788 K08M4_RS04730 e7126b4a0a20ae06b0571918688cf67a 306 Pfam PF00850 Histone deacetylase domain 30 286 4.8E-53 T 05-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 K08M4_RS04730 e7126b4a0a20ae06b0571918688cf67a 306 Gene3D G3DSA:3.40.800.20 2 286 3.8E-65 T 05-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 K08M4_RS04730 e7126b4a0a20ae06b0571918688cf67a 306 PRINTS PR01270 Histone deacetylase superfamily signature 156 171 2.6E-16 T 05-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 K08M4_RS04730 e7126b4a0a20ae06b0571918688cf67a 306 PRINTS PR01270 Histone deacetylase superfamily signature 122 145 2.6E-16 T 05-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 K08M4_RS04730 e7126b4a0a20ae06b0571918688cf67a 306 PRINTS PR01270 Histone deacetylase superfamily signature 230 240 2.6E-16 T 05-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 K08M4_RS04730 e7126b4a0a20ae06b0571918688cf67a 306 SUPERFAMILY SSF52768 3 286 2.73E-80 T 05-07-2017 K08M4_RS15030 bfb27263967def25f0d4c1d12deaff6d 734 Pfam PF08351 Domain of unknown function (DUF1726) 67 120 1.8E-5 T 05-07-2017 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 K08M4_RS15030 bfb27263967def25f0d4c1d12deaff6d 734 Gene3D G3DSA:3.40.50.300 153 294 1.4E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15030 bfb27263967def25f0d4c1d12deaff6d 734 Pfam PF05127 Helicase 189 356 5.5E-56 T 05-07-2017 IPR007807 Helicase domain Reactome: R-HSA-6790901 K08M4_RS15030 bfb27263967def25f0d4c1d12deaff6d 734 Pfam PF13718 GNAT acetyltransferase 2 401 517 5.0E-16 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS15030 bfb27263967def25f0d4c1d12deaff6d 734 Gene3D G3DSA:3.40.630.30 393 561 6.3E-11 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS15030 bfb27263967def25f0d4c1d12deaff6d 734 SUPERFAMILY SSF52540 157 294 4.32E-13 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15030 bfb27263967def25f0d4c1d12deaff6d 734 SUPERFAMILY SSF55729 393 446 3.04E-11 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS15030 bfb27263967def25f0d4c1d12deaff6d 734 SUPERFAMILY SSF55729 483 566 3.04E-11 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS10335 dd6a2bbd479ab9659ba1c2253ad89ec6 410 SUPERFAMILY SSF53383 6 400 1.18E-96 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS10335 dd6a2bbd479ab9659ba1c2253ad89ec6 410 Gene3D G3DSA:3.40.640.10 51 279 6.0E-69 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS10335 dd6a2bbd479ab9659ba1c2253ad89ec6 410 Pfam PF00155 Aminotransferase class I and II 61 392 8.8E-48 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS10335 dd6a2bbd479ab9659ba1c2253ad89ec6 410 Gene3D G3DSA:3.90.1150.10 280 403 7.7E-44 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS06390 d6b694918c873b15da92b41955d63605 91 SMART SM00411 1 90 2.7E-39 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS06390 d6b694918c873b15da92b41955d63605 91 Gene3D G3DSA:4.10.520.10 1 90 1.8E-35 T 05-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 K08M4_RS06390 d6b694918c873b15da92b41955d63605 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 05-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 K08M4_RS06390 d6b694918c873b15da92b41955d63605 91 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.5E-32 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS06390 d6b694918c873b15da92b41955d63605 91 SUPERFAMILY SSF47729 1 90 9.13E-32 T 05-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 K08M4_RS06390 d6b694918c873b15da92b41955d63605 91 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.7E-18 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS06390 d6b694918c873b15da92b41955d63605 91 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.7E-18 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS06390 d6b694918c873b15da92b41955d63605 91 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.7E-18 T 05-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 K08M4_RS12640 194593992b3767c51cdd9c32c77bfbe5 201 SMART SM00749 133 196 2.5E-5 T 05-07-2017 IPR014004 Transport-associated and nodulation domain, bacteria K08M4_RS12640 194593992b3767c51cdd9c32c77bfbe5 201 SMART SM00749 56 119 11.0 T 05-07-2017 IPR014004 Transport-associated and nodulation domain, bacteria K08M4_RS12640 194593992b3767c51cdd9c32c77bfbe5 201 Pfam PF04972 BON domain 51 118 8.0E-11 T 05-07-2017 IPR007055 BON domain K08M4_RS12640 194593992b3767c51cdd9c32c77bfbe5 201 Pfam PF04972 BON domain 129 193 1.3E-14 T 05-07-2017 IPR007055 BON domain K08M4_RS00155 f3d84b7dde692eeb2f6c013eac3fa62f 127 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 7 125 18.301 T 05-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 K08M4_RS00155 f3d84b7dde692eeb2f6c013eac3fa62f 127 TIGRFAM TIGR00494 crcB: protein CrcB 10 123 4.0E-30 T 05-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 K08M4_RS00155 f3d84b7dde692eeb2f6c013eac3fa62f 127 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 9 120 4.0E-23 T 05-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 K08M4_RS05385 eefef2193f028e4ac16e447fa800cf30 236 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 236 88.659 T 05-07-2017 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 K08M4_RS05385 eefef2193f028e4ac16e447fa800cf30 236 SUPERFAMILY SSF55729 4 230 3.6E-86 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS05385 eefef2193f028e4ac16e447fa800cf30 236 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 41 218 2.4E-75 T 05-07-2017 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 K08M4_RS05385 eefef2193f028e4ac16e447fa800cf30 236 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 39 205 1.7E-67 T 05-07-2017 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 K08M4_RS04145 ec0d76687720149cb5197108132df41d 469 Pfam PF00158 Sigma-54 interaction domain 133 295 5.4E-65 T 05-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 K08M4_RS04145 ec0d76687720149cb5197108132df41d 469 SUPERFAMILY SSF52540 139 370 3.98E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04145 ec0d76687720149cb5197108132df41d 469 Gene3D G3DSA:3.40.50.2300 3 120 2.0E-35 T 05-07-2017 K08M4_RS04145 ec0d76687720149cb5197108132df41d 469 Pfam PF02954 Bacterial regulatory protein, Fis family 420 459 2.7E-12 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS04145 ec0d76687720149cb5197108132df41d 469 Pfam PF00072 Response regulator receiver domain 6 115 1.7E-27 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS04145 ec0d76687720149cb5197108132df41d 469 Gene3D G3DSA:3.40.50.300 128 299 9.8E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04145 ec0d76687720149cb5197108132df41d 469 SMART SM00382 149 296 6.4E-7 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS04145 ec0d76687720149cb5197108132df41d 469 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 342 351 - T 05-07-2017 IPR025944 Sigma-54 interaction domain, conserved site K08M4_RS04145 ec0d76687720149cb5197108132df41d 469 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 215 230 - T 05-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 K08M4_RS04145 ec0d76687720149cb5197108132df41d 469 SUPERFAMILY SSF52172 3 173 1.42E-39 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS04145 ec0d76687720149cb5197108132df41d 469 Gene3D G3DSA:1.10.10.60 416 459 7.1E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS04145 ec0d76687720149cb5197108132df41d 469 SMART SM00448 4 115 1.1E-33 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS04145 ec0d76687720149cb5197108132df41d 469 Gene3D G3DSA:1.10.8.60 302 373 1.1E-24 T 05-07-2017 K08M4_RS04145 ec0d76687720149cb5197108132df41d 469 SUPERFAMILY SSF46689 342 460 2.06E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS01270 97e7f0b87b3fd92e621a9788354ebdd4 172 PIRSF PIRSF016481 1 172 3.1E-55 T 05-07-2017 IPR007446 Pilus assembly protein PilP K08M4_RS01270 97e7f0b87b3fd92e621a9788354ebdd4 172 Pfam PF04351 Pilus assembly protein, PilP 26 171 1.4E-41 T 05-07-2017 IPR007446 Pilus assembly protein PilP K08M4_RS20915 a137009f625773da924bcadc3f364573 289 SUPERFAMILY SSF53850 90 288 1.66E-46 T 05-07-2017 K08M4_RS20915 a137009f625773da924bcadc3f364573 289 Gene3D G3DSA:3.40.190.10 92 176 8.0E-26 T 05-07-2017 K08M4_RS20915 a137009f625773da924bcadc3f364573 289 Gene3D G3DSA:1.10.10.10 5 87 3.4E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20915 a137009f625773da924bcadc3f364573 289 Pfam PF03466 LysR substrate binding domain 89 288 5.0E-47 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS20915 a137009f625773da924bcadc3f364573 289 Gene3D G3DSA:3.40.190.10 177 256 2.7E-20 T 05-07-2017 K08M4_RS20915 a137009f625773da924bcadc3f364573 289 SUPERFAMILY SSF46785 4 87 1.72E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20915 a137009f625773da924bcadc3f364573 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 63 1.4E-17 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS09445 45ac4c864464f494338b69c245b506b5 164 SUPERFAMILY SSF50891 1 162 2.63E-57 T 05-07-2017 IPR029000 Cyclophilin-like domain K08M4_RS09445 45ac4c864464f494338b69c245b506b5 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 15 30 1.3E-10 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS09445 45ac4c864464f494338b69c245b506b5 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 41 53 1.3E-10 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS09445 45ac4c864464f494338b69c245b506b5 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 118 133 1.3E-10 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS09445 45ac4c864464f494338b69c245b506b5 164 Gene3D G3DSA:2.40.100.10 2 162 2.9E-52 T 05-07-2017 IPR029000 Cyclophilin-like domain K08M4_RS09445 45ac4c864464f494338b69c245b506b5 164 PIRSF PIRSF001467 1 163 9.7E-27 T 05-07-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 K08M4_RS09445 45ac4c864464f494338b69c245b506b5 164 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 36 53 - T 05-07-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 K08M4_RS09445 45ac4c864464f494338b69c245b506b5 164 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 2 159 9.1E-47 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS09650 8fdd34a6619d290f1ba8ce59dae33573 378 Gene3D G3DSA:3.40.50.620 8 223 1.5E-95 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS09650 8fdd34a6619d290f1ba8ce59dae33573 378 Gene3D G3DSA:2.30.30.280 225 294 2.7E-30 T 05-07-2017 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 K08M4_RS09650 8fdd34a6619d290f1ba8ce59dae33573 378 SUPERFAMILY SSF52402 9 256 1.3E-55 T 05-07-2017 K08M4_RS09650 8fdd34a6619d290f1ba8ce59dae33573 378 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 11 375 39.281 T 05-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 K08M4_RS09650 8fdd34a6619d290f1ba8ce59dae33573 378 Pfam PF03054 tRNA methyl transferase 11 374 1.6E-138 T 05-07-2017 K08M4_RS09650 8fdd34a6619d290f1ba8ce59dae33573 378 Gene3D G3DSA:2.40.30.10 297 377 3.1E-32 T 05-07-2017 K08M4_RS09650 8fdd34a6619d290f1ba8ce59dae33573 378 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 11 374 5.3E-149 T 05-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 K08M4_RS09525 8fdd34a6619d290f1ba8ce59dae33573 378 Gene3D G3DSA:3.40.50.620 8 223 1.5E-95 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS09525 8fdd34a6619d290f1ba8ce59dae33573 378 Gene3D G3DSA:2.30.30.280 225 294 2.7E-30 T 05-07-2017 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 K08M4_RS09525 8fdd34a6619d290f1ba8ce59dae33573 378 SUPERFAMILY SSF52402 9 256 1.3E-55 T 05-07-2017 K08M4_RS09525 8fdd34a6619d290f1ba8ce59dae33573 378 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 11 375 39.281 T 05-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 K08M4_RS09525 8fdd34a6619d290f1ba8ce59dae33573 378 Pfam PF03054 tRNA methyl transferase 11 374 1.6E-138 T 05-07-2017 K08M4_RS09525 8fdd34a6619d290f1ba8ce59dae33573 378 Gene3D G3DSA:2.40.30.10 297 377 3.1E-32 T 05-07-2017 K08M4_RS09525 8fdd34a6619d290f1ba8ce59dae33573 378 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 11 374 5.3E-149 T 05-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 K08M4_RS04585 d0128a9e2025bf6ca69f4040da7a8e4d 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.3E-13 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS04585 d0128a9e2025bf6ca69f4040da7a8e4d 291 Gene3D G3DSA:3.40.190.10 91 176 2.7E-22 T 05-07-2017 K08M4_RS04585 d0128a9e2025bf6ca69f4040da7a8e4d 291 Gene3D G3DSA:3.40.190.10 177 257 1.2E-15 T 05-07-2017 K08M4_RS04585 d0128a9e2025bf6ca69f4040da7a8e4d 291 SUPERFAMILY SSF46785 1 83 6.39E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS04585 d0128a9e2025bf6ca69f4040da7a8e4d 291 SUPERFAMILY SSF53850 88 288 6.21E-38 T 05-07-2017 K08M4_RS04585 d0128a9e2025bf6ca69f4040da7a8e4d 291 Gene3D G3DSA:1.10.10.10 1 82 9.6E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS04585 d0128a9e2025bf6ca69f4040da7a8e4d 291 Pfam PF03466 LysR substrate binding domain 88 286 5.7E-40 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS19260 aa0f565164b47743e373338d16f83841 806 SUPERFAMILY SSF48695 65 87 1.32E-78 T 05-07-2017 IPR011031 Multihaem cytochrome K08M4_RS19260 aa0f565164b47743e373338d16f83841 806 SUPERFAMILY SSF48695 132 255 1.32E-78 T 05-07-2017 IPR011031 Multihaem cytochrome K08M4_RS19260 aa0f565164b47743e373338d16f83841 806 SUPERFAMILY SSF48695 296 610 1.32E-78 T 05-07-2017 IPR011031 Multihaem cytochrome K08M4_RS19260 aa0f565164b47743e373338d16f83841 806 Gene3D G3DSA:1.10.710.10 64 107 7.9E-41 T 05-07-2017 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 K08M4_RS19260 aa0f565164b47743e373338d16f83841 806 Gene3D G3DSA:1.10.710.10 356 460 7.9E-41 T 05-07-2017 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 K08M4_RS19260 aa0f565164b47743e373338d16f83841 806 Gene3D G3DSA:1.10.710.10 194 316 7.9E-41 T 05-07-2017 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 K08M4_RS19260 aa0f565164b47743e373338d16f83841 806 SMART SM00028 687 720 67.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS19260 aa0f565164b47743e373338d16f83841 806 SMART SM00028 653 686 0.4 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS19260 aa0f565164b47743e373338d16f83841 806 SMART SM00028 619 652 4.9E-4 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS19260 aa0f565164b47743e373338d16f83841 806 Pfam PF13424 Tetratricopeptide repeat 624 683 8.4E-8 T 05-07-2017 K08M4_RS19260 aa0f565164b47743e373338d16f83841 806 SUPERFAMILY SSF48452 604 780 4.55E-22 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS19260 aa0f565164b47743e373338d16f83841 806 Gene3D G3DSA:1.25.40.10 597 782 7.0E-27 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS19260 aa0f565164b47743e373338d16f83841 806 Pfam PF13435 Cytochrome c554 and c-prime 70 95 0.016 T 05-07-2017 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 K08M4_RS19260 aa0f565164b47743e373338d16f83841 806 Pfam PF13435 Cytochrome c554 and c-prime 203 241 5.4E-4 T 05-07-2017 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 K08M4_RS02280 9dc7dc1818adf75795835e1798b74d68 252 SUPERFAMILY SSF52540 5 217 1.78E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02280 9dc7dc1818adf75795835e1798b74d68 252 Gene3D G3DSA:3.40.50.300 6 219 3.0E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02280 9dc7dc1818adf75795835e1798b74d68 252 SMART SM00382 26 202 2.4E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS02280 9dc7dc1818adf75795835e1798b74d68 252 Pfam PF00005 ABC transporter 17 157 3.9E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS15035 dce2759645dacb4511e61d9b4f7bc411 556 Pfam PF03961 Protein of unknown function (DUF342) 82 543 1.3E-120 T 05-07-2017 IPR005646 Protein of unknown function DUF342 K08M4_RS16615 15c5a1974226683f10e34d74ad56065d 204 PIRSF PIRSF006324 1 203 3.9E-41 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS16615 15c5a1974226683f10e34d74ad56065d 204 Pfam PF01810 LysE type translocator 15 201 5.4E-32 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS07535 ae08c38b1a9d4bbef4fd1683348f2097 67 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 10 32 5.2E-5 T 05-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal K08M4_RS07535 ae08c38b1a9d4bbef4fd1683348f2097 67 TIGRFAM TIGR02811 formate_TAT: formate dehydrogenase region TAT target 2 67 3.4E-31 T 05-07-2017 IPR014177 Putative formate dehydrogenase, TAT signal-containing K08M4_RS07535 ae08c38b1a9d4bbef4fd1683348f2097 67 PIRSF PIRSF036704 1 67 1.0E-33 T 05-07-2017 IPR014177 Putative formate dehydrogenase, TAT signal-containing K08M4_RS07535 ae08c38b1a9d4bbef4fd1683348f2097 67 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 10 37 4.5E-5 T 05-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal K08M4_RS19160 65917ccbb2b3f4874633dea9c8129343 449 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 41 449 2.7E-88 T 05-07-2017 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 K08M4_RS19160 65917ccbb2b3f4874633dea9c8129343 449 Gene3D G3DSA:2.40.50.100 299 331 2.8E-7 T 05-07-2017 K08M4_RS19160 65917ccbb2b3f4874633dea9c8129343 449 Gene3D G3DSA:2.40.50.100 79 110 2.8E-7 T 05-07-2017 K08M4_RS19160 65917ccbb2b3f4874633dea9c8129343 449 Pfam PF13437 HlyD family secretion protein 302 402 6.7E-14 T 05-07-2017 K08M4_RS19160 65917ccbb2b3f4874633dea9c8129343 449 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 428 448 2.0E-29 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS19160 65917ccbb2b3f4874633dea9c8129343 449 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 347 371 2.0E-29 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS19160 65917ccbb2b3f4874633dea9c8129343 449 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 413 428 2.0E-29 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS19160 65917ccbb2b3f4874633dea9c8129343 449 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 371 394 2.0E-29 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS19160 65917ccbb2b3f4874633dea9c8129343 449 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 88 108 2.0E-29 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS19160 65917ccbb2b3f4874633dea9c8129343 449 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 46 69 2.0E-29 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS19160 65917ccbb2b3f4874633dea9c8129343 449 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 314 335 2.0E-29 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS04355 bf987b9a48d16cdf08f692879438736e 435 SUPERFAMILY SSF53901 293 433 4.61E-31 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS04355 bf987b9a48d16cdf08f692879438736e 435 PIRSF PIRSF000429 8 435 5.5E-117 T 05-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 K08M4_RS04355 bf987b9a48d16cdf08f692879438736e 435 Gene3D G3DSA:3.40.47.10 14 133 2.0E-52 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS04355 bf987b9a48d16cdf08f692879438736e 435 Gene3D G3DSA:3.40.47.10 220 299 2.0E-52 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS04355 bf987b9a48d16cdf08f692879438736e 435 Gene3D G3DSA:3.40.47.10 174 219 3.6E-47 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS04355 bf987b9a48d16cdf08f692879438736e 435 Gene3D G3DSA:3.40.47.10 303 435 3.6E-47 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS04355 bf987b9a48d16cdf08f692879438736e 435 TIGRFAM TIGR02446 FadI: acetyl-CoA C-acyltransferase FadI 6 435 9.9E-258 T 05-07-2017 IPR012806 Acetyl-CoA C-acyltransferase FadI GO:0005737|GO:0006631|GO:0016042|GO:0016740|GO:0016746 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 K08M4_RS04355 bf987b9a48d16cdf08f692879438736e 435 Pfam PF00108 Thiolase, N-terminal domain 14 286 1.5E-62 T 05-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 K08M4_RS04355 bf987b9a48d16cdf08f692879438736e 435 Pfam PF02803 Thiolase, C-terminal domain 295 433 3.1E-35 T 05-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 K08M4_RS04355 bf987b9a48d16cdf08f692879438736e 435 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 16 433 4.5E-126 T 05-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 K08M4_RS04355 bf987b9a48d16cdf08f692879438736e 435 SUPERFAMILY SSF53901 14 294 5.76E-60 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS06655 0a923d68b96973cdb9f2c36dd3b76fdd 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.3E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS06655 0a923d68b96973cdb9f2c36dd3b76fdd 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.3E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS06655 0a923d68b96973cdb9f2c36dd3b76fdd 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.3E-8 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS06655 0a923d68b96973cdb9f2c36dd3b76fdd 290 SUPERFAMILY SSF46785 3 111 5.3E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06655 0a923d68b96973cdb9f2c36dd3b76fdd 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 3.3E-18 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS06655 0a923d68b96973cdb9f2c36dd3b76fdd 290 Pfam PF03466 LysR substrate binding domain 89 288 1.9E-42 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS06655 0a923d68b96973cdb9f2c36dd3b76fdd 290 Gene3D G3DSA:3.40.190.10 90 176 1.1E-20 T 05-07-2017 K08M4_RS06655 0a923d68b96973cdb9f2c36dd3b76fdd 290 Gene3D G3DSA:1.10.10.10 5 86 8.9E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06655 0a923d68b96973cdb9f2c36dd3b76fdd 290 SUPERFAMILY SSF53850 91 289 6.32E-40 T 05-07-2017 K08M4_RS06655 0a923d68b96973cdb9f2c36dd3b76fdd 290 Gene3D G3DSA:3.40.190.10 177 260 9.4E-19 T 05-07-2017 K08M4_RS02985 552dec405fca6c99ed8104659cfc3a46 327 SMART SM00382 34 231 2.9E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS02985 552dec405fca6c99ed8104659cfc3a46 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 317 1.4E-23 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS02985 552dec405fca6c99ed8104659cfc3a46 327 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS02985 552dec405fca6c99ed8104659cfc3a46 327 Pfam PF00005 ABC transporter 26 181 1.8E-26 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS02985 552dec405fca6c99ed8104659cfc3a46 327 SUPERFAMILY SSF52540 5 252 4.76E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02985 552dec405fca6c99ed8104659cfc3a46 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 297 9.6E-18 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS02985 552dec405fca6c99ed8104659cfc3a46 327 Gene3D G3DSA:3.40.50.300 4 253 2.5E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10065 a3bec6778c25e3ece39684f293e33ecf 144 Pfam PF13673 Acetyltransferase (GNAT) domain 29 127 1.2E-12 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS10065 a3bec6778c25e3ece39684f293e33ecf 144 Gene3D G3DSA:3.40.630.30 3 129 7.3E-32 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS10065 a3bec6778c25e3ece39684f293e33ecf 144 SUPERFAMILY SSF55729 14 128 1.25E-23 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS02470 e41837989e45baeabd54362381ff60cd 245 Gene3D G3DSA:3.20.20.70 3 242 5.5E-112 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS02470 e41837989e45baeabd54362381ff60cd 245 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 6 238 7.8E-105 T 05-07-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 K08M4_RS02470 e41837989e45baeabd54362381ff60cd 245 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 243 131.42 T 05-07-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 K08M4_RS02470 e41837989e45baeabd54362381ff60cd 245 SUPERFAMILY SSF63892 4 241 5.75E-101 T 05-07-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 K08M4_RS02470 e41837989e45baeabd54362381ff60cd 245 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 6 239 2.8E-98 T 05-07-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 K08M4_RS16040 1a505d37072aebfbc7f8a0160385ea42 440 SUPERFAMILY SSF53098 107 360 3.03E-23 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS16040 1a505d37072aebfbc7f8a0160385ea42 440 Pfam PF13006 Insertion element 4 transposase N-terminal 22 112 3.0E-21 T 05-07-2017 IPR024473 Transposase, IS4, N-terminal K08M4_RS16040 1a505d37072aebfbc7f8a0160385ea42 440 Pfam PF01609 Transposase DDE domain 132 355 1.1E-21 T 05-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 K08M4_RS00765 86e7a8df58c46c56404af1612608a8da 321 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 7 318 33.315 T 05-07-2017 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 K08M4_RS00765 86e7a8df58c46c56404af1612608a8da 321 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 82 318 4.2E-67 T 05-07-2017 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 K08M4_RS00765 86e7a8df58c46c56404af1612608a8da 321 Gene3D G3DSA:2.30.30.100 272 319 2.3E-21 T 05-07-2017 K08M4_RS00765 86e7a8df58c46c56404af1612608a8da 321 SUPERFAMILY SSF50037 272 318 5.95E-11 T 05-07-2017 IPR008988 Transcriptional repressor, C-terminal K08M4_RS00765 86e7a8df58c46c56404af1612608a8da 321 Pfam PF03099 Biotin/lipoate A/B protein ligase family 84 208 1.8E-21 T 05-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 K08M4_RS00765 86e7a8df58c46c56404af1612608a8da 321 Gene3D G3DSA:3.30.930.10 72 270 1.1E-60 T 05-07-2017 K08M4_RS00765 86e7a8df58c46c56404af1612608a8da 321 SUPERFAMILY SSF55681 76 269 1.37E-60 T 05-07-2017 K08M4_RS00765 86e7a8df58c46c56404af1612608a8da 321 Pfam PF08279 HTH domain 10 59 1.6E-11 T 05-07-2017 IPR013196 Helix-turn-helix, type 11 K08M4_RS00765 86e7a8df58c46c56404af1612608a8da 321 SUPERFAMILY SSF46785 3 60 2.45E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS00765 86e7a8df58c46c56404af1612608a8da 321 Pfam PF02237 Biotin protein ligase C terminal domain 272 318 7.1E-12 T 05-07-2017 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 K08M4_RS00765 86e7a8df58c46c56404af1612608a8da 321 Gene3D G3DSA:1.10.10.10 2 62 5.9E-22 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS11290 1ffa54525adfbfb157f841e5162174e7 528 Pfam PF03806 AbgT putative transporter family 19 526 2.2E-226 T 05-07-2017 IPR004697 p-aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 K08M4_RS16495 15e9b7fc9f68b6067bce1d9bd5485995 89 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 86 2.1E-19 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS16495 15e9b7fc9f68b6067bce1d9bd5485995 89 Gene3D G3DSA:3.40.50.270 1 87 3.4E-16 T 05-07-2017 K08M4_RS16495 15e9b7fc9f68b6067bce1d9bd5485995 89 SUPERFAMILY SSF52794 1 87 9.29E-22 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS01765 a95bd6506cc5bb6d007eeee26cb55674 536 SUPERFAMILY SSF161098 277 521 1.83E-28 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS01765 a95bd6506cc5bb6d007eeee26cb55674 536 SUPERFAMILY SSF161098 12 257 1.31E-40 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS01765 a95bd6506cc5bb6d007eeee26cb55674 536 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 65 257 1.2E-8 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS01765 a95bd6506cc5bb6d007eeee26cb55674 536 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 341 524 1.6E-6 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS01765 a95bd6506cc5bb6d007eeee26cb55674 536 Gene3D G3DSA:1.10.3720.10 12 258 2.1E-33 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS01765 a95bd6506cc5bb6d007eeee26cb55674 536 Gene3D G3DSA:1.10.3720.10 283 525 7.0E-27 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS01765 a95bd6506cc5bb6d007eeee26cb55674 536 TIGRFAM TIGR01253 thiP: thiamine/thiamine pyrophosphate ABC transporter, permease protein 8 517 3.7E-162 T 05-07-2017 IPR005947 Thiamine ABC transporter, permease protein GO:0005215|GO:0015888|GO:0016021 K08M4_RS07150 d6b5b1d5b14a18bf414e2f46ba65ed70 83 SUPERFAMILY SSF101744 1 82 6.8E-23 T 05-07-2017 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 K08M4_RS07150 d6b5b1d5b14a18bf414e2f46ba65ed70 83 Pfam PF07073 Modulator of Rho-dependent transcription termination (ROF) 1 80 6.0E-29 T 05-07-2017 IPR009778 Modulator of Rho-dependent transcription termination K08M4_RS06935 a38a0eb3fcbc4dc0ca9ec884aefdbbb2 1238 SUPERFAMILY SSF52540 1 285 3.76E-32 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06935 a38a0eb3fcbc4dc0ca9ec884aefdbbb2 1238 Gene3D G3DSA:3.40.50.300 1 164 5.9E-25 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06935 a38a0eb3fcbc4dc0ca9ec884aefdbbb2 1238 Gene3D G3DSA:3.40.50.300 1108 1209 2.4E-8 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06935 a38a0eb3fcbc4dc0ca9ec884aefdbbb2 1238 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1120 1191 2.0E-14 T 05-07-2017 K08M4_RS06935 a38a0eb3fcbc4dc0ca9ec884aefdbbb2 1238 Pfam PF13476 AAA domain 5 241 3.1E-27 T 05-07-2017 K08M4_RS06935 a38a0eb3fcbc4dc0ca9ec884aefdbbb2 1238 SUPERFAMILY SSF52540 1052 1209 4.68E-27 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06935 a38a0eb3fcbc4dc0ca9ec884aefdbbb2 1238 SUPERFAMILY SSF52540 1 58 4.68E-27 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08415 5f909273dd66ad9470ea486802959b3c 210 Pfam PF10816 Domain of unknown function (DUF2760) 87 209 1.3E-53 T 05-07-2017 IPR021212 Domain of unknown function DUF2760 K08M4_RS07510 86b20ef5ea3afe3ed04f34008b572cc1 273 Gene3D G3DSA:3.40.140.10 133 270 8.1E-53 T 05-07-2017 K08M4_RS07510 86b20ef5ea3afe3ed04f34008b572cc1 273 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 11 267 26.377 T 05-07-2017 IPR003786 Protein FdhD GO:0016783 K08M4_RS07510 86b20ef5ea3afe3ed04f34008b572cc1 273 Pfam PF02634 FdhD/NarQ family 35 266 2.7E-74 T 05-07-2017 IPR003786 Protein FdhD GO:0016783 K08M4_RS07510 86b20ef5ea3afe3ed04f34008b572cc1 273 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 31 266 2.6E-42 T 05-07-2017 IPR003786 Protein FdhD GO:0016783 K08M4_RS07510 86b20ef5ea3afe3ed04f34008b572cc1 273 PIRSF PIRSF015626 1 271 2.0E-98 T 05-07-2017 IPR003786 Protein FdhD GO:0016783 K08M4_RS07510 86b20ef5ea3afe3ed04f34008b572cc1 273 Gene3D G3DSA:3.10.20.10 36 118 1.6E-16 T 05-07-2017 K08M4_RS07510 86b20ef5ea3afe3ed04f34008b572cc1 273 SUPERFAMILY SSF53927 15 266 4.81E-71 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 K08M4_RS04965 1d96d6b11f2f536cf59a1dce31adf6ca 323 SMART SM00382 32 238 5.8E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS04965 1d96d6b11f2f536cf59a1dce31adf6ca 323 Pfam PF00005 ABC transporter 24 180 1.0E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS04965 1d96d6b11f2f536cf59a1dce31adf6ca 323 Gene3D G3DSA:3.40.50.300 2 254 1.4E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04965 1d96d6b11f2f536cf59a1dce31adf6ca 323 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS04965 1d96d6b11f2f536cf59a1dce31adf6ca 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 296 7.4E-19 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS04965 1d96d6b11f2f536cf59a1dce31adf6ca 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 315 1.6E-24 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS04965 1d96d6b11f2f536cf59a1dce31adf6ca 323 SUPERFAMILY SSF52540 31 301 7.66E-70 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14290 9a68dfb0769a51a621bd66a865c9e510 213 Pfam PF11172 Protein of unknown function (DUF2959) 13 210 2.8E-89 T 05-07-2017 IPR021342 Protein of unknown function DUF2959 K08M4_RS04110 3878c9a90cc4e27dcf2ad6afbffcaa0a 392 Pfam PF00700 Bacterial flagellin C-terminal helical region 307 391 5.4E-26 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS04110 3878c9a90cc4e27dcf2ad6afbffcaa0a 392 Pfam PF07196 Flagellin hook IN motif 194 247 3.1E-6 T 05-07-2017 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 K08M4_RS04110 3878c9a90cc4e27dcf2ad6afbffcaa0a 392 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 4.1E-42 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS04110 3878c9a90cc4e27dcf2ad6afbffcaa0a 392 Gene3D G3DSA:1.20.1330.10 54 171 2.7E-61 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS04110 3878c9a90cc4e27dcf2ad6afbffcaa0a 392 Gene3D G3DSA:1.20.1330.10 294 347 2.7E-61 T 05-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 K08M4_RS04110 3878c9a90cc4e27dcf2ad6afbffcaa0a 392 SUPERFAMILY SSF64518 1 391 2.75E-95 T 05-07-2017 K08M4_RS04110 3878c9a90cc4e27dcf2ad6afbffcaa0a 392 PRINTS PR00207 Flagellin signature 37 54 1.7E-26 T 05-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 K08M4_RS04110 3878c9a90cc4e27dcf2ad6afbffcaa0a 392 PRINTS PR00207 Flagellin signature 76 95 1.7E-26 T 05-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 K08M4_RS04110 3878c9a90cc4e27dcf2ad6afbffcaa0a 392 PRINTS PR00207 Flagellin signature 111 134 1.7E-26 T 05-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 K08M4_RS00655 9cb4c4a1ddbc5b74424ef29f48737fa6 586 Gene3D G3DSA:2.40.170.20 154 586 6.2E-76 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS00655 9cb4c4a1ddbc5b74424ef29f48737fa6 586 Hamap MF_01531 Vitamin B12 transporter BtuB [btuB]. 1 586 34.097 T 05-07-2017 IPR010101 TonB-dependent vitamin B12 transporter BtuB GO:0004872|GO:0015235|GO:0015889|GO:0016020 K08M4_RS00655 9cb4c4a1ddbc5b74424ef29f48737fa6 586 Pfam PF00593 TonB dependent receptor 372 585 1.5E-28 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS00655 9cb4c4a1ddbc5b74424ef29f48737fa6 586 SUPERFAMILY SSF56935 29 586 2.23E-108 T 05-07-2017 K08M4_RS00655 9cb4c4a1ddbc5b74424ef29f48737fa6 586 Pfam PF07715 TonB-dependent Receptor Plug Domain 43 148 4.4E-27 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS00655 9cb4c4a1ddbc5b74424ef29f48737fa6 586 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 36 - T 05-07-2017 IPR010916 TonB box, conserved site K08M4_RS00655 9cb4c4a1ddbc5b74424ef29f48737fa6 586 Gene3D G3DSA:2.170.130.10 21 153 3.2E-37 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS07110 de565cfc62a470f0311f012c06d600e8 138 SUPERFAMILY SSF54593 3 129 6.85E-28 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS07110 de565cfc62a470f0311f012c06d600e8 138 Gene3D G3DSA:3.10.180.10 7 128 7.8E-23 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS07110 de565cfc62a470f0311f012c06d600e8 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 125 2.7E-18 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain K08M4_RS02180 8a5dec52d082934c43f96b6ff1de7bda 316 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 2 120 5.3E-48 T 05-07-2017 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 K08M4_RS02180 8a5dec52d082934c43f96b6ff1de7bda 316 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 124 296 2.0E-79 T 05-07-2017 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 K08M4_RS02180 8a5dec52d082934c43f96b6ff1de7bda 316 Gene3D G3DSA:3.30.1490.20 138 191 5.5E-31 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 K08M4_RS02180 8a5dec52d082934c43f96b6ff1de7bda 316 TIGRFAM TIGR01380 glut_syn: glutathione synthase 2 311 8.0E-139 T 05-07-2017 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 K08M4_RS02180 8a5dec52d082934c43f96b6ff1de7bda 316 Gene3D G3DSA:3.30.470.20 192 299 9.6E-50 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS02180 8a5dec52d082934c43f96b6ff1de7bda 316 Gene3D G3DSA:3.40.50.20 2 129 3.1E-56 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS02180 8a5dec52d082934c43f96b6ff1de7bda 316 SUPERFAMILY SSF52440 2 122 1.27E-46 T 05-07-2017 IPR016185 Pre-ATP-grasp domain K08M4_RS02180 8a5dec52d082934c43f96b6ff1de7bda 316 SUPERFAMILY SSF56059 123 313 3.98E-59 T 05-07-2017 K08M4_RS02180 8a5dec52d082934c43f96b6ff1de7bda 316 Hamap MF_00162 Glutathione synthetase [gshB]. 1 316 179.107 T 05-07-2017 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 K08M4_RS04975 23360d94a64999cc7aa1a82765ae1615 315 SUPERFAMILY SSF47616 167 312 7.8E-37 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS04975 23360d94a64999cc7aa1a82765ae1615 315 Pfam PF13409 Glutathione S-transferase, N-terminal domain 56 147 1.4E-21 T 05-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 K08M4_RS04975 23360d94a64999cc7aa1a82765ae1615 315 Pfam PF13410 Glutathione S-transferase, C-terminal domain 192 263 1.8E-13 T 05-07-2017 K08M4_RS04975 23360d94a64999cc7aa1a82765ae1615 315 SUPERFAMILY SSF52833 31 150 3.62E-15 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS04975 23360d94a64999cc7aa1a82765ae1615 315 Gene3D G3DSA:3.40.30.10 30 166 3.3E-19 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS04975 23360d94a64999cc7aa1a82765ae1615 315 Gene3D G3DSA:1.20.1050.10 167 276 4.4E-27 T 05-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like K08M4_RS04975 23360d94a64999cc7aa1a82765ae1615 315 PIRSF PIRSF015753 4 312 7.9E-134 T 05-07-2017 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 K08M4_RS12745 ac5ab19ca7beb0d57186afd4c46871ef 418 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 202 416 2.5E-48 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS12745 ac5ab19ca7beb0d57186afd4c46871ef 418 Gene3D G3DSA:1.10.287.950 173 386 3.9E-58 T 05-07-2017 K08M4_RS12745 ac5ab19ca7beb0d57186afd4c46871ef 418 SMART SM00283 156 417 3.8E-69 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS12745 ac5ab19ca7beb0d57186afd4c46871ef 418 SMART SM00304 89 141 0.0014 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS12745 ac5ab19ca7beb0d57186afd4c46871ef 418 SUPERFAMILY SSF58104 109 418 2.09E-76 T 05-07-2017 K08M4_RS12745 ac5ab19ca7beb0d57186afd4c46871ef 418 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 283 312 1.6E-23 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS12745 ac5ab19ca7beb0d57186afd4c46871ef 418 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 254 281 1.6E-23 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS12745 ac5ab19ca7beb0d57186afd4c46871ef 418 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 68 88 1.6E-23 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS12745 ac5ab19ca7beb0d57186afd4c46871ef 418 Pfam PF00672 HAMP domain 71 136 1.1E-6 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS20225 875de65b14c8310ac29a6004dd3c8af2 668 Hamap MF_01036 Exoribonuclease 2 [rnb]. 1 650 42.169 T 05-07-2017 IPR011804 Ribonuclease II GO:0003723|GO:0006401|GO:0008859 K08M4_RS20225 875de65b14c8310ac29a6004dd3c8af2 668 Pfam PF08206 Ribonuclease B OB domain 24 80 1.8E-16 T 05-07-2017 IPR013223 Ribonuclease B, N-terminal OB domain K08M4_RS20225 875de65b14c8310ac29a6004dd3c8af2 668 SUPERFAMILY SSF50249 83 173 4.2E-26 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS20225 875de65b14c8310ac29a6004dd3c8af2 668 SUPERFAMILY SSF50249 192 563 6.17E-107 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS20225 875de65b14c8310ac29a6004dd3c8af2 668 Gene3D G3DSA:2.40.50.140 571 647 1.7E-4 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS20225 875de65b14c8310ac29a6004dd3c8af2 668 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 6 648 1.5E-182 T 05-07-2017 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 K08M4_RS20225 875de65b14c8310ac29a6004dd3c8af2 668 Pfam PF00773 RNB domain 193 521 5.1E-85 T 05-07-2017 K08M4_RS20225 875de65b14c8310ac29a6004dd3c8af2 668 SUPERFAMILY SSF50249 568 649 3.86E-20 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS20225 875de65b14c8310ac29a6004dd3c8af2 668 SUPERFAMILY SSF50249 8 80 2.33E-14 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS20225 875de65b14c8310ac29a6004dd3c8af2 668 TIGRFAM TIGR02062 RNase_B: exoribonuclease II 1 649 0.0 T 05-07-2017 IPR011804 Ribonuclease II GO:0003723|GO:0006401|GO:0008859 K08M4_RS20225 875de65b14c8310ac29a6004dd3c8af2 668 SMART SM00316 566 650 3.2E-4 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS20225 875de65b14c8310ac29a6004dd3c8af2 668 SMART SM00955 193 523 9.9E-112 T 05-07-2017 K08M4_RS20225 875de65b14c8310ac29a6004dd3c8af2 668 SMART SM00357 23 79 1.6E-8 T 05-07-2017 IPR011129 Cold shock protein GO:0003676 K08M4_RS20225 875de65b14c8310ac29a6004dd3c8af2 668 Pfam PF00575 S1 RNA binding domain 565 645 4.4E-9 T 05-07-2017 IPR003029 S1 domain GO:0003676 K08M4_RS20225 875de65b14c8310ac29a6004dd3c8af2 668 ProSitePatterns PS01175 Ribonuclease II family signature. 490 514 - T 05-07-2017 IPR022966 Ribonuclease II/R, conserved site K08M4_RS00500 47a6432e645bdf940b32f38f37bbb0f9 163 Pfam PF00782 Dual specificity phosphatase, catalytic domain 32 146 2.0E-8 T 05-07-2017 IPR000340 Dual specificity phosphatase, catalytic domain GO:0006470|GO:0008138 K08M4_RS00500 47a6432e645bdf940b32f38f37bbb0f9 163 Gene3D G3DSA:3.90.190.10 9 158 2.0E-36 T 05-07-2017 IPR029021 Protein-tyrosine phosphatase-like K08M4_RS00500 47a6432e645bdf940b32f38f37bbb0f9 163 SUPERFAMILY SSF52799 10 157 1.24E-29 T 05-07-2017 IPR029021 Protein-tyrosine phosphatase-like K08M4_RS00500 47a6432e645bdf940b32f38f37bbb0f9 163 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 109 119 - T 05-07-2017 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 K08M4_RS21180 3e219c12eff9b0162c7f3ee570fdb613 391 Pfam PF02958 Ecdysteroid kinase 229 329 4.4E-8 T 05-07-2017 IPR004119 Protein of unknown function DUF227 K08M4_RS21180 3e219c12eff9b0162c7f3ee570fdb613 391 Gene3D G3DSA:3.90.1200.10 183 345 1.6E-10 T 05-07-2017 K08M4_RS21180 3e219c12eff9b0162c7f3ee570fdb613 391 SUPERFAMILY SSF56112 183 381 1.0E-17 T 05-07-2017 IPR011009 Protein kinase-like domain K08M4_RS21180 3e219c12eff9b0162c7f3ee570fdb613 391 SUPERFAMILY SSF56112 45 154 1.0E-17 T 05-07-2017 IPR011009 Protein kinase-like domain K08M4_RS21180 3e219c12eff9b0162c7f3ee570fdb613 391 SMART SM00587 164 328 0.0035 T 05-07-2017 IPR015897 CHK kinase-like K08M4_RS01750 561aa4567d0d3044a5e2a126015deee3 452 Gene3D G3DSA:3.40.1190.10 92 312 1.2E-84 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS01750 561aa4567d0d3044a5e2a126015deee3 452 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 448 1.4E-252 T 05-07-2017 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 K08M4_RS01750 561aa4567d0d3044a5e2a126015deee3 452 Pfam PF08245 Mur ligase middle domain 108 291 3.9E-21 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS01750 561aa4567d0d3044a5e2a126015deee3 452 Pfam PF01225 Mur ligase family, catalytic domain 2 101 1.3E-19 T 05-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 K08M4_RS01750 561aa4567d0d3044a5e2a126015deee3 452 SUPERFAMILY SSF53244 311 448 1.05E-37 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS01750 561aa4567d0d3044a5e2a126015deee3 452 SUPERFAMILY SSF53623 97 308 7.59E-51 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS01750 561aa4567d0d3044a5e2a126015deee3 452 SUPERFAMILY SSF51984 1 89 6.02E-23 T 05-07-2017 K08M4_RS01750 561aa4567d0d3044a5e2a126015deee3 452 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 449 58.553 T 05-07-2017 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 K08M4_RS01750 561aa4567d0d3044a5e2a126015deee3 452 Gene3D G3DSA:3.90.190.20 313 448 3.1E-34 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS01750 561aa4567d0d3044a5e2a126015deee3 452 Gene3D G3DSA:3.40.50.720 1 90 8.0E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS01750 561aa4567d0d3044a5e2a126015deee3 452 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 382 2.3E-10 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS09965 2466ee860666da6073e967acbc65ea85 658 SMART SM00849 126 345 2.5E-8 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS09965 2466ee860666da6073e967acbc65ea85 658 Pfam PF14864 Alkyl sulfatase C-terminal 530 648 1.5E-12 T 05-07-2017 IPR029229 Alkyl sulfatase, C-terminal K08M4_RS09965 2466ee860666da6073e967acbc65ea85 658 Pfam PF14863 Alkyl sulfatase dimerisation 382 519 1.7E-41 T 05-07-2017 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 K08M4_RS09965 2466ee860666da6073e967acbc65ea85 658 Pfam PF00753 Metallo-beta-lactamase superfamily 130 345 8.9E-18 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS09965 2466ee860666da6073e967acbc65ea85 658 SUPERFAMILY SSF55718 530 650 1.18E-14 T 05-07-2017 IPR003033 SCP2 sterol-binding domain K08M4_RS09965 2466ee860666da6073e967acbc65ea85 658 SUPERFAMILY SSF56281 92 520 9.24E-97 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS09965 2466ee860666da6073e967acbc65ea85 658 Gene3D G3DSA:3.60.15.10 255 375 3.5E-36 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS09965 2466ee860666da6073e967acbc65ea85 658 Gene3D G3DSA:3.60.15.10 111 219 3.5E-36 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS10715 27eb8aecb593c8e56f54389dc18b3ff7 181 Gene3D G3DSA:3.60.21.10 2 168 6.3E-45 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS10715 27eb8aecb593c8e56f54389dc18b3ff7 181 SUPERFAMILY SSF56300 2 175 3.36E-37 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS10715 27eb8aecb593c8e56f54389dc18b3ff7 181 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 163 5.2E-24 T 05-07-2017 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 K08M4_RS10715 27eb8aecb593c8e56f54389dc18b3ff7 181 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 169 2.5E-29 T 05-07-2017 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 K08M4_RS01235 bd3fa0e22019fd41324ff2d3b0a161e9 242 Gene3D G3DSA:3.40.30.10 3 163 1.4E-62 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS01235 bd3fa0e22019fd41324ff2d3b0a161e9 242 TIGRFAM TIGR02190 GlrX-dom: glutaredoxin-family domain 164 241 8.9E-41 T 05-07-2017 IPR011906 Glutaredoxin domain KEGG: 00480+1.11.1.15 K08M4_RS01235 bd3fa0e22019fd41324ff2d3b0a161e9 242 ProSitePatterns PS00195 Glutaredoxin active site. 175 191 - T 05-07-2017 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 K08M4_RS01235 bd3fa0e22019fd41324ff2d3b0a161e9 242 Gene3D G3DSA:3.40.30.10 171 240 2.4E-25 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS01235 bd3fa0e22019fd41324ff2d3b0a161e9 242 PRINTS PR00160 Glutaredoxin signature 173 191 2.6E-14 T 05-07-2017 IPR014025 Glutaredoxin subgroup K08M4_RS01235 bd3fa0e22019fd41324ff2d3b0a161e9 242 PRINTS PR00160 Glutaredoxin signature 228 241 2.6E-14 T 05-07-2017 IPR014025 Glutaredoxin subgroup K08M4_RS01235 bd3fa0e22019fd41324ff2d3b0a161e9 242 PRINTS PR00160 Glutaredoxin signature 214 227 2.6E-14 T 05-07-2017 IPR014025 Glutaredoxin subgroup K08M4_RS01235 bd3fa0e22019fd41324ff2d3b0a161e9 242 SUPERFAMILY SSF52833 2 240 5.79E-47 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS01235 bd3fa0e22019fd41324ff2d3b0a161e9 242 Pfam PF00462 Glutaredoxin 173 231 2.6E-18 T 05-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 K08M4_RS01235 bd3fa0e22019fd41324ff2d3b0a161e9 242 Pfam PF08534 Redoxin 5 160 4.0E-32 T 05-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 K08M4_RS01835 9b6d98668eee2e1c92d1353018020806 323 SMART SM00116 275 322 2.1 T 05-07-2017 IPR000644 CBS domain K08M4_RS01835 9b6d98668eee2e1c92d1353018020806 323 SMART SM00116 210 258 0.021 T 05-07-2017 IPR000644 CBS domain K08M4_RS01835 9b6d98668eee2e1c92d1353018020806 323 SUPERFAMILY SSF53697 10 318 6.45E-65 T 05-07-2017 K08M4_RS01835 9b6d98668eee2e1c92d1353018020806 323 Pfam PF01380 SIS domain 41 172 7.2E-32 T 05-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 K08M4_RS01835 9b6d98668eee2e1c92d1353018020806 323 Gene3D G3DSA:3.40.50.10490 10 191 2.9E-53 T 05-07-2017 K08M4_RS01835 9b6d98668eee2e1c92d1353018020806 323 Pfam PF00571 CBS domain 268 320 2.0E-4 T 05-07-2017 IPR000644 CBS domain K08M4_RS01835 9b6d98668eee2e1c92d1353018020806 323 Pfam PF00571 CBS domain 203 258 1.8E-5 T 05-07-2017 IPR000644 CBS domain K08M4_RS01835 9b6d98668eee2e1c92d1353018020806 323 Gene3D G3DSA:3.10.580.10 192 320 7.7E-38 T 05-07-2017 K08M4_RS01835 9b6d98668eee2e1c92d1353018020806 323 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 45 313 3.0E-111 T 05-07-2017 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 K08M4_RS01835 9b6d98668eee2e1c92d1353018020806 323 PIRSF PIRSF004692 1 323 1.7E-129 T 05-07-2017 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 K08M4_RS11000 37f68b2d028e94aecc9e60b236d3ac61 348 Pfam PF06804 NlpB/DapX lipoprotein 35 335 2.8E-100 T 05-07-2017 IPR010653 NlpB/DapX lipoprotein K08M4_RS11000 37f68b2d028e94aecc9e60b236d3ac61 348 Hamap MF_00924 Outer membrane protein assembly factor BamC [bamC]. 4 337 33.256 T 05-07-2017 IPR014524 Outer membrane protein assembly factor BamC K08M4_RS11000 37f68b2d028e94aecc9e60b236d3ac61 348 PIRSF PIRSF026343 4 339 3.5E-123 T 05-07-2017 IPR014524 Outer membrane protein assembly factor BamC K08M4_RS02100 8f22cf508af14e9691a66403174c6403 377 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 228 256 - T 05-07-2017 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 K08M4_RS02100 8f22cf508af14e9691a66403174c6403 377 SUPERFAMILY SSF53955 188 370 1.18E-37 T 05-07-2017 IPR023346 Lysozyme-like domain K08M4_RS02100 8f22cf508af14e9691a66403174c6403 377 Gene3D G3DSA:1.10.530.10 180 374 6.4E-44 T 05-07-2017 K08M4_RS02100 8f22cf508af14e9691a66403174c6403 377 Pfam PF01464 Transglycosylase SLT domain 211 335 2.4E-29 T 05-07-2017 IPR008258 Transglycosylase SLT domain 1 K08M4_RS02100 8f22cf508af14e9691a66403174c6403 377 Pfam PF11873 Domain of unknown function (DUF3393) 4 206 5.0E-77 T 05-07-2017 IPR024570 Murein transglycosylase-C, N-terminal K08M4_RS20905 1d98c3fba99f7ec51420d41718156cdb 170 Pfam PF00588 SpoU rRNA Methylase family 6 139 2.5E-20 T 05-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 K08M4_RS20905 1d98c3fba99f7ec51420d41718156cdb 170 SUPERFAMILY SSF75217 3 143 2.51E-27 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases K08M4_RS20905 1d98c3fba99f7ec51420d41718156cdb 170 Gene3D G3DSA:3.40.1280.10 3 140 2.4E-20 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal K08M4_RS01870 0eb467255ade74ad00e017b24e712aa4 84 Gene3D G3DSA:3.30.300.90 3 80 9.1E-26 T 05-07-2017 IPR002634 BolA protein K08M4_RS01870 0eb467255ade74ad00e017b24e712aa4 84 PIRSF PIRSF003113 2 83 2.8E-20 T 05-07-2017 IPR002634 BolA protein K08M4_RS01870 0eb467255ade74ad00e017b24e712aa4 84 Pfam PF01722 BolA-like protein 22 74 1.1E-13 T 05-07-2017 IPR002634 BolA protein K08M4_RS01870 0eb467255ade74ad00e017b24e712aa4 84 SUPERFAMILY SSF82657 4 82 2.49E-27 T 05-07-2017 IPR002634 BolA protein K08M4_RS15620 4255c6b5336da90785f3d0cb7a2c4965 350 Pfam PF04986 Putative transposase 138 298 3.4E-37 T 05-07-2017 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 K08M4_RS15620 4255c6b5336da90785f3d0cb7a2c4965 350 Pfam PF14319 Transposase zinc-binding domain 7 114 5.3E-31 T 05-07-2017 IPR026889 Transposase zinc-binding domain K08M4_RS20215 a7d75aac145ce2890a65c2edab22e824 397 Gene3D G3DSA:3.30.420.40 157 357 2.8E-77 T 05-07-2017 K08M4_RS20215 a7d75aac145ce2890a65c2edab22e824 397 TIGRFAM TIGR00016 ackA: acetate kinase 2 396 2.6E-145 T 05-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS20215 a7d75aac145ce2890a65c2edab22e824 397 PIRSF PIRSF000722 2 397 7.6E-134 T 05-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS20215 a7d75aac145ce2890a65c2edab22e824 397 PRINTS PR00471 Acetate kinase family signature 299 312 3.4E-45 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS20215 a7d75aac145ce2890a65c2edab22e824 397 PRINTS PR00471 Acetate kinase family signature 173 186 3.4E-45 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS20215 a7d75aac145ce2890a65c2edab22e824 397 PRINTS PR00471 Acetate kinase family signature 378 390 3.4E-45 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS20215 a7d75aac145ce2890a65c2edab22e824 397 PRINTS PR00471 Acetate kinase family signature 6 17 3.4E-45 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS20215 a7d75aac145ce2890a65c2edab22e824 397 PRINTS PR00471 Acetate kinase family signature 321 337 3.4E-45 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS20215 a7d75aac145ce2890a65c2edab22e824 397 PRINTS PR00471 Acetate kinase family signature 203 224 3.4E-45 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS20215 a7d75aac145ce2890a65c2edab22e824 397 SUPERFAMILY SSF53067 158 396 3.63E-78 T 05-07-2017 K08M4_RS20215 a7d75aac145ce2890a65c2edab22e824 397 Hamap MF_00020 Acetate kinase [ackA]. 1 397 168.958 T 05-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS20215 a7d75aac145ce2890a65c2edab22e824 397 Pfam PF00871 Acetokinase family 6 391 3.6E-141 T 05-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS20215 a7d75aac145ce2890a65c2edab22e824 397 SUPERFAMILY SSF53067 5 196 1.23E-61 T 05-07-2017 K08M4_RS20215 a7d75aac145ce2890a65c2edab22e824 397 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 6 17 - T 05-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS20215 a7d75aac145ce2890a65c2edab22e824 397 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 203 220 - T 05-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 K08M4_RS14855 bea91b7aab5cc053379ad53b7041354b 317 Pfam PF11059 Protein of unknown function (DUF2860) 26 316 5.1E-118 T 05-07-2017 IPR016896 Protein of unknown function DUF2860 K08M4_RS14855 bea91b7aab5cc053379ad53b7041354b 317 PIRSF PIRSF028696 1 317 1.3E-106 T 05-07-2017 IPR016896 Protein of unknown function DUF2860 K08M4_RS16380 1443457d0c8650b9d1e6e2e23242f147 304 SUPERFAMILY SSF50341 11 151 8.89E-30 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS16380 1443457d0c8650b9d1e6e2e23242f147 304 Pfam PF00072 Response regulator receiver domain 175 289 4.8E-14 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS16380 1443457d0c8650b9d1e6e2e23242f147 304 SUPERFAMILY SSF52172 171 292 1.71E-21 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS16380 1443457d0c8650b9d1e6e2e23242f147 304 PIRSF PIRSF002867 3 297 1.9E-84 T 05-07-2017 IPR024181 Chemotaxis response regulator CheV K08M4_RS16380 1443457d0c8650b9d1e6e2e23242f147 304 SMART SM00260 11 147 2.7E-18 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS16380 1443457d0c8650b9d1e6e2e23242f147 304 SMART SM00448 173 290 3.6E-15 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS16380 1443457d0c8650b9d1e6e2e23242f147 304 Gene3D G3DSA:3.40.50.2300 173 290 4.5E-21 T 05-07-2017 K08M4_RS16380 1443457d0c8650b9d1e6e2e23242f147 304 Pfam PF01584 CheW-like domain 14 149 1.3E-30 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS16380 1443457d0c8650b9d1e6e2e23242f147 304 Gene3D G3DSA:2.30.30.40 87 138 3.8E-4 T 05-07-2017 K08M4_RS05315 b59844027989414cb1e741eef291e934 377 SMART SM00558 93 218 6.0E-4 T 05-07-2017 IPR003347 JmjC domain K08M4_RS05315 b59844027989414cb1e741eef291e934 377 Pfam PF08007 Cupin superfamily protein 10 306 1.6E-88 T 05-07-2017 IPR003347 JmjC domain K08M4_RS05315 b59844027989414cb1e741eef291e934 377 Gene3D G3DSA:2.60.120.650 6 208 5.3E-41 T 05-07-2017 K08M4_RS05315 b59844027989414cb1e741eef291e934 377 SUPERFAMILY SSF51197 6 295 1.08E-70 T 05-07-2017 K08M4_RS05215 29bf84632eda9288594f51493082715e 235 SUPERFAMILY SSF52540 45 156 3.41E-22 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05215 29bf84632eda9288594f51493082715e 235 PIRSF PIRSF037290 1 233 2.0E-59 T 05-07-2017 IPR017166 Uncharacterised conserved protein UCP037290 K08M4_RS05215 29bf84632eda9288594f51493082715e 235 Gene3D G3DSA:3.40.50.300 45 156 8.3E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16145 e3e98b5264d9e1372e48cd6608e803de 363 Pfam PF01699 Sodium/calcium exchanger protein 38 192 1.0E-13 T 05-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 K08M4_RS16145 e3e98b5264d9e1372e48cd6608e803de 363 Pfam PF01699 Sodium/calcium exchanger protein 222 361 6.3E-11 T 05-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 K08M4_RS20965 d2923929ae4996f63676def3bec5e244 194 SUPERFAMILY SSF46689 4 81 1.28E-13 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20965 d2923929ae4996f63676def3bec5e244 194 Gene3D G3DSA:1.10.10.60 2 64 2.8E-18 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20965 d2923929ae4996f63676def3bec5e244 194 Gene3D G3DSA:1.10.357.10 75 189 2.4E-14 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS20965 d2923929ae4996f63676def3bec5e244 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 1.5E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS20965 d2923929ae4996f63676def3bec5e244 194 SUPERFAMILY SSF48498 78 191 3.22E-21 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal K08M4_RS06930 d3c59538b87e9e14f2c5aef2599be182 417 Gene3D G3DSA:3.60.21.10 1 282 4.7E-63 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS06930 d3c59538b87e9e14f2c5aef2599be182 417 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 261 4.7E-70 T 05-07-2017 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 K08M4_RS06930 d3c59538b87e9e14f2c5aef2599be182 417 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 283 380 4.2E-27 T 05-07-2017 IPR026843 Nuclease SbcCD subunit D, C-terminal domain K08M4_RS06930 d3c59538b87e9e14f2c5aef2599be182 417 Pfam PF00149 Calcineurin-like phosphoesterase 1 233 8.4E-13 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 K08M4_RS06930 d3c59538b87e9e14f2c5aef2599be182 417 SUPERFAMILY SSF56300 1 343 3.14E-57 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS18910 e2d63361be652e55cdf3bc19ebc96d03 602 SUPERFAMILY SSF109604 396 568 2.2E-37 T 05-07-2017 K08M4_RS18910 e2d63361be652e55cdf3bc19ebc96d03 602 Pfam PF01966 HD domain 405 527 1.1E-16 T 05-07-2017 IPR006674 HD domain K08M4_RS18910 e2d63361be652e55cdf3bc19ebc96d03 602 SMART SM00471 400 537 6.8E-7 T 05-07-2017 IPR003607 HD/PDEase domain K08M4_RS18910 e2d63361be652e55cdf3bc19ebc96d03 602 Gene3D G3DSA:1.10.3210.10 403 571 9.4E-20 T 05-07-2017 IPR006674 HD domain K08M4_RS10845 7f8d9bbe9d198b5221b056365dc44023 493 Gene3D G3DSA:1.10.443.10 230 466 1.4E-15 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS10845 7f8d9bbe9d198b5221b056365dc44023 493 SUPERFAMILY SSF56349 137 466 5.59E-15 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS03550 2a9db79a2e772239ac3a88dee5f4080e 315 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 10 57 8.3E-18 T 05-07-2017 IPR025713 Motility protein B, N-terminal domain K08M4_RS03550 2a9db79a2e772239ac3a88dee5f4080e 315 Pfam PF00691 OmpA family 195 293 5.1E-17 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS03550 2a9db79a2e772239ac3a88dee5f4080e 315 Gene3D G3DSA:3.30.1330.60 171 299 7.5E-31 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS03550 2a9db79a2e772239ac3a88dee5f4080e 315 SUPERFAMILY SSF103088 182 299 2.09E-29 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS00275 7b1417986c70ed795e447f190196a807 497 SUPERFAMILY SSF53067 9 129 2.56E-36 T 05-07-2017 K08M4_RS00275 7b1417986c70ed795e447f190196a807 497 Hamap MF_01550 Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [gppA]. 2 495 57.886 T 05-07-2017 IPR023709 Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase GO:0008894|GO:0015974 KEGG: 00230+3.6.1.40 K08M4_RS00275 7b1417986c70ed795e447f190196a807 497 Pfam PF02541 Ppx/GppA phosphatase family 23 303 1.5E-86 T 05-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 K08M4_RS00275 7b1417986c70ed795e447f190196a807 497 SUPERFAMILY SSF53067 134 305 7.29E-41 T 05-07-2017 K08M4_RS00275 7b1417986c70ed795e447f190196a807 497 PIRSF PIRSF001267 1 496 3.4E-178 T 05-07-2017 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 K08M4_RS00275 7b1417986c70ed795e447f190196a807 497 SUPERFAMILY SSF109604 309 495 1.0E-40 T 05-07-2017 K08M4_RS00275 7b1417986c70ed795e447f190196a807 497 Gene3D G3DSA:3.30.420.40 4 129 4.4E-42 T 05-07-2017 K08M4_RS00275 7b1417986c70ed795e447f190196a807 497 Gene3D G3DSA:3.30.420.150 130 304 2.8E-49 T 05-07-2017 K08M4_RS18450 1ab76dc99e3a4ff819beb9530b0a2b25 488 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 8 233 3.4E-27 T 05-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain K08M4_RS18450 1ab76dc99e3a4ff819beb9530b0a2b25 488 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 488 200.171 T 05-07-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 K08M4_RS18450 1ab76dc99e3a4ff819beb9530b0a2b25 488 Gene3D G3DSA:3.40.50.300 6 240 4.3E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18450 1ab76dc99e3a4ff819beb9530b0a2b25 488 SUPERFAMILY SSF52317 254 448 7.25E-41 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS18450 1ab76dc99e3a4ff819beb9530b0a2b25 488 SUPERFAMILY SSF52540 7 240 3.1E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18450 1ab76dc99e3a4ff819beb9530b0a2b25 488 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 254 439 8.9E-60 T 05-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 K08M4_RS18450 1ab76dc99e3a4ff819beb9530b0a2b25 488 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 8 482 2.9E-158 T 05-07-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 K08M4_RS18450 1ab76dc99e3a4ff819beb9530b0a2b25 488 Gene3D G3DSA:3.40.50.880 253 449 3.9E-29 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS16225 48d3ae6cd40526a414c941b4b1687018 532 SUPERFAMILY SSF51621 430 515 1.53E-123 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS16225 48d3ae6cd40526a414c941b4b1687018 532 SUPERFAMILY SSF51621 9 393 1.53E-123 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS16225 48d3ae6cd40526a414c941b4b1687018 532 Gene3D G3DSA:3.20.20.60 5 271 4.3E-137 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS16225 48d3ae6cd40526a414c941b4b1687018 532 Gene3D G3DSA:3.20.20.60 304 393 4.3E-137 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS16225 48d3ae6cd40526a414c941b4b1687018 532 Gene3D G3DSA:3.20.20.60 430 514 4.3E-137 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS16225 48d3ae6cd40526a414c941b4b1687018 532 Pfam PF00463 Isocitrate lyase family 99 270 5.1E-19 T 05-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 K08M4_RS16225 48d3ae6cd40526a414c941b4b1687018 532 Pfam PF00463 Isocitrate lyase family 433 531 4.6E-13 T 05-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 K08M4_RS16225 48d3ae6cd40526a414c941b4b1687018 532 Pfam PF00463 Isocitrate lyase family 318 392 2.3E-13 T 05-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 K08M4_RS03840 47eb2872126f5bd6d3191ac3e04deafa 157 SUPERFAMILY SSF55826 2 156 2.22E-41 T 05-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 K08M4_RS03840 47eb2872126f5bd6d3191ac3e04deafa 157 PIRSF PIRSF006181 1 157 3.0E-50 T 05-07-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC K08M4_RS03840 47eb2872126f5bd6d3191ac3e04deafa 157 Pfam PF04073 Aminoacyl-tRNA editing domain 32 145 2.6E-24 T 05-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 K08M4_RS03840 47eb2872126f5bd6d3191ac3e04deafa 157 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 2 156 2.3E-57 T 05-07-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC K08M4_RS03840 47eb2872126f5bd6d3191ac3e04deafa 157 Gene3D G3DSA:3.90.960.10 1 156 4.8E-56 T 05-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 K08M4_RS15380 98bee8cd2f5d9f691efeaaea11bdc360 328 Gene3D G3DSA:3.40.190.10 285 311 2.4E-19 T 05-07-2017 K08M4_RS15380 98bee8cd2f5d9f691efeaaea11bdc360 328 Gene3D G3DSA:3.40.190.10 93 184 2.4E-19 T 05-07-2017 K08M4_RS15380 98bee8cd2f5d9f691efeaaea11bdc360 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 4.8E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS15380 98bee8cd2f5d9f691efeaaea11bdc360 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 4.8E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS15380 98bee8cd2f5d9f691efeaaea11bdc360 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 4.8E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS15380 98bee8cd2f5d9f691efeaaea11bdc360 328 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 70 1.1E-15 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS15380 98bee8cd2f5d9f691efeaaea11bdc360 328 Pfam PF03466 LysR substrate binding domain 99 308 8.0E-21 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS15380 98bee8cd2f5d9f691efeaaea11bdc360 328 SUPERFAMILY SSF46785 9 87 1.36E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15380 98bee8cd2f5d9f691efeaaea11bdc360 328 Gene3D G3DSA:3.40.190.10 185 280 2.0E-21 T 05-07-2017 K08M4_RS15380 98bee8cd2f5d9f691efeaaea11bdc360 328 SUPERFAMILY SSF53850 93 307 1.76E-37 T 05-07-2017 K08M4_RS15380 98bee8cd2f5d9f691efeaaea11bdc360 328 Gene3D G3DSA:1.10.10.10 6 88 1.5E-27 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS08250 a486b6b630b8135e35f86541f69b1b0a 400 Gene3D G3DSA:1.20.1250.20 7 183 1.2E-16 T 05-07-2017 K08M4_RS08250 a486b6b630b8135e35f86541f69b1b0a 400 Gene3D G3DSA:1.20.1250.20 206 388 5.2E-16 T 05-07-2017 K08M4_RS08250 a486b6b630b8135e35f86541f69b1b0a 400 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 19 382 2.4E-58 T 05-07-2017 IPR010645 Uncharacterised MFS-type transporter YbfB K08M4_RS08250 a486b6b630b8135e35f86541f69b1b0a 400 SUPERFAMILY SSF103473 7 387 7.19E-41 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS01435 9b9c9487e6ab949c6daed7d8dc250379 91 Pfam PF04077 DsrH like protein 10 87 3.3E-19 T 05-07-2017 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 K08M4_RS01435 9b9c9487e6ab949c6daed7d8dc250379 91 SUPERFAMILY SSF75169 1 91 1.11E-18 T 05-07-2017 IPR027396 DsrEFH-like K08M4_RS01435 9b9c9487e6ab949c6daed7d8dc250379 91 Gene3D G3DSA:3.40.1260.10 1 89 1.3E-16 T 05-07-2017 IPR027396 DsrEFH-like K08M4_RS01435 9b9c9487e6ab949c6daed7d8dc250379 91 TIGRFAM TIGR03011 sulf_tusB_dsrH: sulfur relay protein TusB/DsrH 3 91 1.3E-19 T 05-07-2017 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 K08M4_RS02335 818d2aee3558374dd0bc2cf54057491c 288 Pfam PF05552 Conserved TM helix 21 69 4.9E-13 T 05-07-2017 IPR008910 Conserved TM helix K08M4_RS02335 818d2aee3558374dd0bc2cf54057491c 288 Gene3D G3DSA:2.30.30.60 135 184 4.7E-20 T 05-07-2017 K08M4_RS02335 818d2aee3558374dd0bc2cf54057491c 288 SUPERFAMILY SSF82861 33 118 1.06E-17 T 05-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 K08M4_RS02335 818d2aee3558374dd0bc2cf54057491c 288 Gene3D G3DSA:3.30.70.100 188 272 1.1E-30 T 05-07-2017 K08M4_RS02335 818d2aee3558374dd0bc2cf54057491c 288 SUPERFAMILY SSF82689 186 284 3.14E-34 T 05-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 K08M4_RS02335 818d2aee3558374dd0bc2cf54057491c 288 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 149 183 - T 05-07-2017 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 K08M4_RS02335 818d2aee3558374dd0bc2cf54057491c 288 SUPERFAMILY SSF50182 120 185 1.11E-17 T 05-07-2017 IPR010920 LSM domain K08M4_RS02335 818d2aee3558374dd0bc2cf54057491c 288 Pfam PF00924 Mechanosensitive ion channel 77 274 1.4E-57 T 05-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 K08M4_RS01715 b68bdc33a9e7b35c3bfd6220bd4fc233 183 Gene3D G3DSA:3.40.30.10 119 177 1.4E-4 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS01715 b68bdc33a9e7b35c3bfd6220bd4fc233 183 Pfam PF09695 Bacterial protein of unknown function (YtfJ_HI0045) 24 181 4.2E-74 T 05-07-2017 IPR006513 Conserved hypothetical protein CHP01626, YtfJ K08M4_RS01715 b68bdc33a9e7b35c3bfd6220bd4fc233 183 TIGRFAM TIGR01626 ytfJ_HI0045: conserved hypothetical protein YtfJ-family, TIGR01626 1 181 1.3E-84 T 05-07-2017 IPR006513 Conserved hypothetical protein CHP01626, YtfJ K08M4_RS16670 6ddd9b228e22acdb74c55ccd30997f15 364 Gene3D G3DSA:3.40.50.2300 25 177 1.3E-87 T 05-07-2017 K08M4_RS16670 6ddd9b228e22acdb74c55ccd30997f15 364 Gene3D G3DSA:3.40.50.2300 318 340 1.3E-87 T 05-07-2017 K08M4_RS16670 6ddd9b228e22acdb74c55ccd30997f15 364 SUPERFAMILY SSF53822 27 363 7.35E-73 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS16670 6ddd9b228e22acdb74c55ccd30997f15 364 Gene3D G3DSA:3.40.50.2300 188 317 9.0E-22 T 05-07-2017 K08M4_RS16670 6ddd9b228e22acdb74c55ccd30997f15 364 Pfam PF13407 Periplasmic binding protein domain 69 322 3.5E-13 T 05-07-2017 IPR025997 Periplasmic binding protein K08M4_RS08570 6c7fc91dadd2ea76c24552730f6d9fab 396 SUPERFAMILY SSF53383 1 395 5.86E-110 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS08570 6c7fc91dadd2ea76c24552730f6d9fab 396 Pfam PF00155 Aminotransferase class I and II 27 391 8.7E-82 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS08570 6c7fc91dadd2ea76c24552730f6d9fab 396 PRINTS PR00799 Aspartate aminotransferase signature 341 359 2.5E-38 T 05-07-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 K08M4_RS08570 6c7fc91dadd2ea76c24552730f6d9fab 396 PRINTS PR00799 Aspartate aminotransferase signature 206 218 2.5E-38 T 05-07-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 K08M4_RS08570 6c7fc91dadd2ea76c24552730f6d9fab 396 PRINTS PR00799 Aspartate aminotransferase signature 273 298 2.5E-38 T 05-07-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 K08M4_RS08570 6c7fc91dadd2ea76c24552730f6d9fab 396 PRINTS PR00799 Aspartate aminotransferase signature 175 194 2.5E-38 T 05-07-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 K08M4_RS08570 6c7fc91dadd2ea76c24552730f6d9fab 396 Gene3D G3DSA:3.40.640.10 45 315 9.4E-103 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS08570 6c7fc91dadd2ea76c24552730f6d9fab 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 243 256 - T 05-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 K08M4_RS19275 37cf77154be15e66918850bb08b88674 217 Hamap MF_00789 UPF0319 protein YccT [yccT]. 5 217 25.635 T 05-07-2017 IPR018635 Uncharacterised protein family UPF0319 K08M4_RS19275 37cf77154be15e66918850bb08b88674 217 Pfam PF09829 Uncharacterized protein conserved in bacteria (DUF2057) 25 212 7.0E-54 T 05-07-2017 IPR018635 Uncharacterised protein family UPF0319 K08M4_RS18585 5f77f9bf4f854bbb1fe7816af424be90 712 Gene3D G3DSA:2.40.170.20 156 712 5.5E-97 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS18585 5f77f9bf4f854bbb1fe7816af424be90 712 TIGRFAM TIGR01786 TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein 29 712 3.5E-130 T 05-07-2017 IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 K08M4_RS18585 5f77f9bf4f854bbb1fe7816af424be90 712 TIGRFAM TIGR01785 TonB-hemin: TonB-dependent heme/hemoglobin receptor family protein 28 712 5.1E-110 T 05-07-2017 IPR011276 TonB-dependent haem/haemoglobin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 K08M4_RS18585 5f77f9bf4f854bbb1fe7816af424be90 712 Pfam PF07715 TonB-dependent Receptor Plug Domain 42 152 4.8E-25 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS18585 5f77f9bf4f854bbb1fe7816af424be90 712 SUPERFAMILY SSF56935 29 712 4.4E-112 T 05-07-2017 K08M4_RS18585 5f77f9bf4f854bbb1fe7816af424be90 712 Pfam PF00593 TonB dependent receptor 459 710 1.8E-33 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS18585 5f77f9bf4f854bbb1fe7816af424be90 712 Gene3D G3DSA:2.170.130.10 24 155 1.3E-35 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS07810 f79189e441e79169c3a8b0ebfb97ba0b 1613 PIRSF PIRSF036761 1 1610 0.0 T 05-07-2017 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 K08M4_RS07810 f79189e441e79169c3a8b0ebfb97ba0b 1613 SUPERFAMILY SSF51735 1084 1278 3.22E-26 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS07810 f79189e441e79169c3a8b0ebfb97ba0b 1613 SUPERFAMILY SSF51735 946 1048 3.22E-26 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS07810 f79189e441e79169c3a8b0ebfb97ba0b 1613 SUPERFAMILY SSF53223 756 941 8.92E-25 T 05-07-2017 K08M4_RS07810 f79189e441e79169c3a8b0ebfb97ba0b 1613 Gene3D G3DSA:3.40.50.720 943 1054 3.4E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS07810 f79189e441e79169c3a8b0ebfb97ba0b 1613 Gene3D G3DSA:3.40.50.720 1089 1203 3.4E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS07810 f79189e441e79169c3a8b0ebfb97ba0b 1613 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 76 1603 0.0 T 05-07-2017 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 SUPERFAMILY SSF52172 1025 1142 4.13E-18 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 SUPERFAMILY SSF55785 626 741 6.28E-9 T 05-07-2017 IPR000014 PAS domain K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 Gene3D G3DSA:3.30.450.20 626 741 1.0E-13 T 05-07-2017 K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 SMART SM00387 897 1006 1.6E-28 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 Gene3D G3DSA:3.30.565.10 854 1005 2.7E-38 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 PRINTS PR00344 Bacterial sensor protein C-terminal signature 933 947 2.1E-10 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 PRINTS PR00344 Bacterial sensor protein C-terminal signature 990 1003 2.1E-10 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 PRINTS PR00344 Bacterial sensor protein C-terminal signature 966 984 2.1E-10 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 PRINTS PR00344 Bacterial sensor protein C-terminal signature 951 961 2.1E-10 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 SMART SM00448 1026 1139 4.3E-15 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 Gene3D G3DSA:3.40.50.2300 1024 1142 1.8E-17 T 05-07-2017 K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 898 1003 3.9E-19 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 SUPERFAMILY SSF55874 843 1003 1.22E-38 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 Pfam PF00512 His Kinase A (phospho-acceptor) domain 788 853 4.1E-11 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 Gene3D G3DSA:1.10.287.130 784 849 1.2E-11 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 SMART SM00388 788 853 4.0E-12 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 Pfam PF00072 Response regulator receiver domain 1028 1139 1.3E-11 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 SUPERFAMILY SSF47384 773 854 4.51E-13 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS00955 428be65cc7b842cbad55143d3e0db54a 1143 Pfam PF12860 PAS fold 634 748 1.5E-43 T 05-07-2017 K08M4_RS05490 26596ac27cd0c66eb77a10223883236d 501 Pfam PF14400 Inactive transglutaminase fused to 7 transmembrane helices 24 183 2.3E-56 T 05-07-2017 IPR025838 Inactive transglutaminase fused to 7 transmembrane helices K08M4_RS05490 26596ac27cd0c66eb77a10223883236d 501 Pfam PF14402 7 transmembrane helices usually fused to an inactive transglutaminase 191 498 2.5E-135 T 05-07-2017 IPR025840 7 transmembrane helices usually fused to an inactive transglutaminase K08M4_RS07160 46f3f584839ef36aa037d6e6b915bac0 149 Pfam PF14526 Integron-associated effector binding protein 3 148 1.5E-24 T 05-07-2017 IPR029441 Integron-associated effector binding protein K08M4_RS07160 46f3f584839ef36aa037d6e6b915bac0 149 Gene3D G3DSA:3.20.80.10 1 149 2.4E-52 T 05-07-2017 IPR011256 Regulatory factor, effector binding domain K08M4_RS07160 46f3f584839ef36aa037d6e6b915bac0 149 SUPERFAMILY SSF55136 2 147 5.75E-14 T 05-07-2017 IPR011256 Regulatory factor, effector binding domain K08M4_RS07160 46f3f584839ef36aa037d6e6b915bac0 149 SMART SM00871 1 149 7.5E-21 T 05-07-2017 IPR010499 Bacterial transcription activator, effector binding K08M4_RS09720 d1f2c47cbd0b775ad36d553829fbf157 198 SUPERFAMILY SSF89392 20 197 1.06E-49 T 05-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX K08M4_RS09720 d1f2c47cbd0b775ad36d553829fbf157 198 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 3 196 30.987 T 05-07-2017 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 K08M4_RS09720 d1f2c47cbd0b775ad36d553829fbf157 198 Gene3D G3DSA:2.50.20.10 20 197 2.4E-51 T 05-07-2017 K08M4_RS09720 d1f2c47cbd0b775ad36d553829fbf157 198 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 5 197 8.1E-61 T 05-07-2017 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 K08M4_RS09720 d1f2c47cbd0b775ad36d553829fbf157 198 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 30 185 8.3E-55 T 05-07-2017 IPR004564 Outer membrane lipoprotein carrier protein LolA-like K08M4_RS18550 a7a2a5b6ec0eadb22577d1789960b0f7 103 Gene3D G3DSA:3.30.780.10 23 103 8.7E-34 T 05-07-2017 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 K08M4_RS18550 a7a2a5b6ec0eadb22577d1789960b0f7 103 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 3 103 1.4E-38 T 05-07-2017 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 K08M4_RS18550 a7a2a5b6ec0eadb22577d1789960b0f7 103 SUPERFAMILY SSF55159 3 99 4.71E-26 T 05-07-2017 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 K08M4_RS18550 a7a2a5b6ec0eadb22577d1789960b0f7 103 PIRSF PIRSF037511 1 103 2.2E-33 T 05-07-2017 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 K08M4_RS18550 a7a2a5b6ec0eadb22577d1789960b0f7 103 Pfam PF01253 Translation initiation factor SUI1 27 97 3.1E-18 T 05-07-2017 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 K08M4_RS10955 ad9a6382b4526b0bf6295461eed32283 288 SUPERFAMILY SSF52402 162 287 2.26E-11 T 05-07-2017 K08M4_RS10955 ad9a6382b4526b0bf6295461eed32283 288 Gene3D G3DSA:3.40.50.620 172 287 7.0E-10 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS10955 ad9a6382b4526b0bf6295461eed32283 288 Pfam PF00582 Universal stress protein family 179 286 1.7E-7 T 05-07-2017 IPR006016 UspA GO:0006950 K08M4_RS19620 fe7dca75d17232b4819385770719b11f 728 TIGRFAM TIGR01667 YCCS_YHJK: integral membrane protein, YccS/YhfK family 10 711 3.6E-238 T 05-07-2017 IPR010020 Integral membrane protein, YccS/YhfK K08M4_RS19620 fe7dca75d17232b4819385770719b11f 728 Pfam PF13515 Fusaric acid resistance protein-like 405 524 3.1E-22 T 05-07-2017 K08M4_RS19620 fe7dca75d17232b4819385770719b11f 728 Pfam PF12805 FUSC-like inner membrane protein yccS 68 348 1.8E-109 T 05-07-2017 IPR032692 Integral membrane protein YccS, N-terminal K08M4_RS19620 fe7dca75d17232b4819385770719b11f 728 TIGRFAM TIGR01666 YCCS: TIGR01666 family membrane protein 10 712 0.0 T 05-07-2017 IPR010019 Integral membrane protein, YccS K08M4_RS09845 50630877accd89c2453d07be46c8df11 255 Pfam PF10972 Peptidoglycan-binding protein, CsiV 7 253 4.2E-65 T 05-07-2017 IPR021241 Peptidoglycan-binding protein, CsiV K08M4_RS12695 72d1379ccf2891917875516700f7a5cc 354 TIGRFAM TIGR02038 protease_degS: periplasmic serine peptidase DegS 2 352 2.3E-166 T 05-07-2017 IPR011783 Peptidase S1C, DegS GO:0004252|GO:0006508 K08M4_RS12695 72d1379ccf2891917875516700f7a5cc 354 SUPERFAMILY SSF50156 240 347 3.76E-20 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS12695 72d1379ccf2891917875516700f7a5cc 354 Gene3D G3DSA:2.40.10.10 146 258 3.9E-39 T 05-07-2017 K08M4_RS12695 72d1379ccf2891917875516700f7a5cc 354 SUPERFAMILY SSF50494 43 266 5.19E-61 T 05-07-2017 IPR009003 Peptidase S1, PA clan K08M4_RS12695 72d1379ccf2891917875516700f7a5cc 354 Pfam PF13180 PDZ domain 257 347 6.6E-14 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS12695 72d1379ccf2891917875516700f7a5cc 354 Pfam PF13365 Trypsin-like peptidase domain 82 216 1.5E-32 T 05-07-2017 K08M4_RS12695 72d1379ccf2891917875516700f7a5cc 354 PRINTS PR00834 HtrA/DegQ protease family signature 91 103 1.1E-46 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 K08M4_RS12695 72d1379ccf2891917875516700f7a5cc 354 PRINTS PR00834 HtrA/DegQ protease family signature 187 204 1.1E-46 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 K08M4_RS12695 72d1379ccf2891917875516700f7a5cc 354 PRINTS PR00834 HtrA/DegQ protease family signature 209 226 1.1E-46 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 K08M4_RS12695 72d1379ccf2891917875516700f7a5cc 354 PRINTS PR00834 HtrA/DegQ protease family signature 112 132 1.1E-46 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 K08M4_RS12695 72d1379ccf2891917875516700f7a5cc 354 PRINTS PR00834 HtrA/DegQ protease family signature 297 309 1.1E-46 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 K08M4_RS12695 72d1379ccf2891917875516700f7a5cc 354 PRINTS PR00834 HtrA/DegQ protease family signature 152 176 1.1E-46 T 05-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 K08M4_RS12695 72d1379ccf2891917875516700f7a5cc 354 Gene3D G3DSA:2.40.10.10 44 145 2.0E-33 T 05-07-2017 K08M4_RS12695 72d1379ccf2891917875516700f7a5cc 354 SMART SM00228 257 339 3.0E-6 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS12695 72d1379ccf2891917875516700f7a5cc 354 Gene3D G3DSA:2.30.42.10 259 351 1.3E-22 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS20705 07cc61b42ac6700e4d045f2192cd1316 357 Gene3D G3DSA:2.40.50.100 81 113 2.0E-8 T 05-07-2017 K08M4_RS20705 07cc61b42ac6700e4d045f2192cd1316 357 Gene3D G3DSA:2.40.50.100 231 267 2.0E-8 T 05-07-2017 K08M4_RS20705 07cc61b42ac6700e4d045f2192cd1316 357 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 107 308 8.7E-8 T 05-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain K08M4_RS20780 d5fd82c90c1badf983638b8dd34f0f45 486 SUPERFAMILY SSF52540 2 254 2.19E-37 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20780 d5fd82c90c1badf983638b8dd34f0f45 486 Pfam PF00005 ABC transporter 303 437 6.0E-19 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS20780 d5fd82c90c1badf983638b8dd34f0f45 486 Pfam PF00005 ABC transporter 21 170 4.7E-18 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS20780 d5fd82c90c1badf983638b8dd34f0f45 486 ProSitePatterns PS00211 ABC transporters family signature. 410 424 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS20780 d5fd82c90c1badf983638b8dd34f0f45 486 SMART SM00382 29 224 1.4E-6 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS20780 d5fd82c90c1badf983638b8dd34f0f45 486 SMART SM00382 311 485 1.4E-5 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS20780 d5fd82c90c1badf983638b8dd34f0f45 486 Gene3D G3DSA:3.40.50.300 284 483 9.9E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20780 d5fd82c90c1badf983638b8dd34f0f45 486 Gene3D G3DSA:3.40.50.300 2 251 2.6E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20780 d5fd82c90c1badf983638b8dd34f0f45 486 SUPERFAMILY SSF52540 282 484 2.82E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11745 9dfe860d11d8259741f03664a0e87573 626 Gene3D G3DSA:2.40.70.10 494 614 4.1E-38 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS11745 9dfe860d11d8259741f03664a0e87573 626 Gene3D G3DSA:2.40.70.10 219 337 5.0E-15 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS11745 9dfe860d11d8259741f03664a0e87573 626 Gene3D G3DSA:2.40.70.10 39 87 4.3E-36 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS11745 9dfe860d11d8259741f03664a0e87573 626 Gene3D G3DSA:2.40.70.10 359 479 5.2E-8 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS11745 9dfe860d11d8259741f03664a0e87573 626 Gene3D G3DSA:2.40.70.10 125 206 4.3E-36 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS11745 9dfe860d11d8259741f03664a0e87573 626 Pfam PF05618 Putative ATP-dependant zinc protease 494 621 1.9E-26 T 05-07-2017 K08M4_RS11745 9dfe860d11d8259741f03664a0e87573 626 Pfam PF05618 Putative ATP-dependant zinc protease 130 216 2.4E-9 T 05-07-2017 K08M4_RS11745 9dfe860d11d8259741f03664a0e87573 626 SUPERFAMILY SSF50630 361 486 5.62E-12 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS11745 9dfe860d11d8259741f03664a0e87573 626 SUPERFAMILY SSF50630 221 343 2.36E-12 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS11745 9dfe860d11d8259741f03664a0e87573 626 SUPERFAMILY SSF50630 41 81 1.07E-23 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS11745 9dfe860d11d8259741f03664a0e87573 626 SUPERFAMILY SSF50630 119 214 1.07E-23 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS11745 9dfe860d11d8259741f03664a0e87573 626 SUPERFAMILY SSF50630 494 622 1.39E-34 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS11670 ca635ef91f1b9088742d19feda7b0a19 168 Pfam PF12019 Type II transport protein GspH 41 141 1.2E-8 T 05-07-2017 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 K08M4_RS11670 ca635ef91f1b9088742d19feda7b0a19 168 Pfam PF13633 Prokaryotic N-terminal methylation site 3 28 3.2E-8 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS11670 ca635ef91f1b9088742d19feda7b0a19 168 SUPERFAMILY SSF54523 5 91 6.75E-14 T 05-07-2017 K08M4_RS11670 ca635ef91f1b9088742d19feda7b0a19 168 PIRSF PIRSF024622 1 168 8.9E-57 T 05-07-2017 IPR016824 Tfp pilus assembly protein FimT K08M4_RS11670 ca635ef91f1b9088742d19feda7b0a19 168 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 24 1.9E-7 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS11670 ca635ef91f1b9088742d19feda7b0a19 168 Gene3D G3DSA:3.30.700.10 5 50 1.8E-5 T 05-07-2017 K08M4_RS11670 ca635ef91f1b9088742d19feda7b0a19 168 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 3 23 - T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS19080 a3f0284377f46b30cd3e4305cadcb65d 459 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 28 454 6.3E-220 T 05-07-2017 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 K08M4_RS19080 a3f0284377f46b30cd3e4305cadcb65d 459 Gene3D G3DSA:3.40.50.1100 197 453 3.3E-41 T 05-07-2017 K08M4_RS19080 a3f0284377f46b30cd3e4305cadcb65d 459 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 459 275.112 T 05-07-2017 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 K08M4_RS19080 a3f0284377f46b30cd3e4305cadcb65d 459 SUPERFAMILY SSF53686 88 452 2.33E-51 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme K08M4_RS19080 a3f0284377f46b30cd3e4305cadcb65d 459 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 124 138 - T 05-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 K08M4_RS19080 a3f0284377f46b30cd3e4305cadcb65d 459 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 91 416 7.2E-52 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme K08M4_RS05500 d9767bef02e0ec34c41c68bf9cc1e582 323 Pfam PF08003 Protein of unknown function (DUF1698) 7 322 1.8E-169 T 05-07-2017 IPR027555 tRNA (mo5U34)-methyltransferase-like K08M4_RS05500 d9767bef02e0ec34c41c68bf9cc1e582 323 Hamap MF_01590 tRNA U34 carboxymethyltransferase [cmoB]. 13 322 53.937 T 05-07-2017 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 K08M4_RS05500 d9767bef02e0ec34c41c68bf9cc1e582 323 SUPERFAMILY SSF53335 91 323 1.66E-34 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS05500 d9767bef02e0ec34c41c68bf9cc1e582 323 Gene3D G3DSA:3.40.50.150 93 275 3.2E-27 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS05500 d9767bef02e0ec34c41c68bf9cc1e582 323 TIGRFAM TIGR00452 TIGR00452: tRNA (mo5U34)-methyltransferase 12 321 1.0E-146 T 05-07-2017 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 K08M4_RS21410 8a5ba12a4a9935cf5cdc9cda144dc004 197 Gene3D G3DSA:1.10.357.10 55 194 2.7E-47 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS21410 8a5ba12a4a9935cf5cdc9cda144dc004 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 53 9.4E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS21410 8a5ba12a4a9935cf5cdc9cda144dc004 197 SUPERFAMILY SSF46689 3 69 6.31E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS21410 8a5ba12a4a9935cf5cdc9cda144dc004 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 6.2E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS21410 8a5ba12a4a9935cf5cdc9cda144dc004 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 6.2E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS21410 8a5ba12a4a9935cf5cdc9cda144dc004 197 SUPERFAMILY SSF48498 80 193 8.9E-20 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal K08M4_RS21410 8a5ba12a4a9935cf5cdc9cda144dc004 197 Gene3D G3DSA:1.10.10.60 5 54 6.3E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS04120 babd4f2da1efb20262d90cc321b0147c 684 Pfam PF07196 Flagellin hook IN motif 129 177 3.6E-9 T 05-07-2017 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 K08M4_RS04120 babd4f2da1efb20262d90cc321b0147c 684 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 10 107 1.0E-20 T 05-07-2017 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 K08M4_RS04120 babd4f2da1efb20262d90cc321b0147c 684 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 449 674 2.7E-49 T 05-07-2017 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 K08M4_RS06235 bb25f891133f6f472be7ee9190d51e6b 247 SMART SM00479 59 233 6.5E-16 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS06235 bb25f891133f6f472be7ee9190d51e6b 247 SUPERFAMILY SSF53098 53 231 1.19E-35 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS06235 bb25f891133f6f472be7ee9190d51e6b 247 Gene3D G3DSA:3.30.420.10 56 233 2.7E-37 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS06235 bb25f891133f6f472be7ee9190d51e6b 247 Pfam PF00929 Exonuclease 61 224 7.0E-19 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS11125 fb14ca4e45d4eaae7add106c046f8c68 280 SUPERFAMILY SSF56219 60 274 5.76E-23 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS11125 fb14ca4e45d4eaae7add106c046f8c68 280 Hamap MF_01119 UPF0294 protein YafD [yafD]. 1 278 50.732 T 05-07-2017 IPR022958 Uncharacterised protein family UPF0294 K08M4_RS11125 fb14ca4e45d4eaae7add106c046f8c68 280 Gene3D G3DSA:3.60.10.10 61 214 8.9E-8 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS11125 fb14ca4e45d4eaae7add106c046f8c68 280 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 66 270 1.2E-10 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS02185 b5bce0535bbaa526b342076ecbd9f6fe 243 Gene3D G3DSA:2.40.240.20 1 70 6.3E-25 T 05-07-2017 K08M4_RS02185 b5bce0535bbaa526b342076ecbd9f6fe 243 PIRSF PIRSF015601 2 242 6.1E-53 T 05-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS02185 b5bce0535bbaa526b342076ecbd9f6fe 243 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 3 242 4.1E-83 T 05-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS02185 b5bce0535bbaa526b342076ecbd9f6fe 243 Gene3D G3DSA:3.40.1280.10 75 242 2.3E-58 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal K08M4_RS02185 b5bce0535bbaa526b342076ecbd9f6fe 243 SUPERFAMILY SSF75217 75 242 1.73E-50 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases K08M4_RS02185 b5bce0535bbaa526b342076ecbd9f6fe 243 SUPERFAMILY SSF88697 2 70 2.73E-16 T 05-07-2017 IPR015947 PUA-like domain K08M4_RS02185 b5bce0535bbaa526b342076ecbd9f6fe 243 Pfam PF04452 RNA methyltransferase 20 236 1.6E-72 T 05-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 K08M4_RS07775 11524f5ce4ff9c98508eaf6183dc1bf6 57 ProDom PD051650 RIBOSOME MODULATION FACTOR E FACTOR-RELATED DIMERIZATION BIOGENESIS RIBOSOMES INVOLVED 70S 1 51 2.0E-20 T 05-07-2017 IPR007040 Ribosome modulation factor K08M4_RS07775 11524f5ce4ff9c98508eaf6183dc1bf6 57 Gene3D G3DSA:1.10.10.620 1 57 2.5E-27 T 05-07-2017 IPR023200 Ribosome modulation factor-like domain K08M4_RS07775 11524f5ce4ff9c98508eaf6183dc1bf6 57 Pfam PF04957 Ribosome modulation factor 1 54 1.9E-27 T 05-07-2017 IPR007040 Ribosome modulation factor K08M4_RS07775 11524f5ce4ff9c98508eaf6183dc1bf6 57 Hamap MF_00919 Ribosome modulation factor [rmf]. 1 55 28.873 T 05-07-2017 IPR007040 Ribosome modulation factor K08M4_RS02525 98ec2e7d9503a3aeb9eb2dd326aa3cec 159 SUPERFAMILY SSF69765 1 157 1.83E-66 T 05-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 K08M4_RS02525 98ec2e7d9503a3aeb9eb2dd326aa3cec 159 Gene3D G3DSA:3.30.1330.50 1 157 1.3E-72 T 05-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 K08M4_RS02525 98ec2e7d9503a3aeb9eb2dd326aa3cec 159 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 157 3.4E-69 T 05-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 K08M4_RS02525 98ec2e7d9503a3aeb9eb2dd326aa3cec 159 Pfam PF02542 YgbB family 2 155 1.9E-66 T 05-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 K08M4_RS02525 98ec2e7d9503a3aeb9eb2dd326aa3cec 159 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 35.999 T 05-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 K08M4_RS02525 98ec2e7d9503a3aeb9eb2dd326aa3cec 159 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 05-07-2017 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 K08M4_RS12410 979f36c6a4522b47f15f765786d8ff10 318 Pfam PF00288 GHMP kinases N terminal domain 90 156 1.1E-13 T 05-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 K08M4_RS12410 979f36c6a4522b47f15f765786d8ff10 318 SUPERFAMILY SSF54211 3 191 1.59E-33 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS12410 979f36c6a4522b47f15f765786d8ff10 318 PIRSF PIRSF000676 1 316 7.3E-80 T 05-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 K08M4_RS12410 979f36c6a4522b47f15f765786d8ff10 318 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 96 107 - T 05-07-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 K08M4_RS12410 979f36c6a4522b47f15f765786d8ff10 318 Gene3D G3DSA:3.30.230.10 2 165 1.2E-43 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup K08M4_RS12410 979f36c6a4522b47f15f765786d8ff10 318 SUPERFAMILY SSF55060 178 294 5.04E-33 T 05-07-2017 IPR013750 GHMP kinase, C-terminal domain K08M4_RS12410 979f36c6a4522b47f15f765786d8ff10 318 TIGRFAM TIGR00191 thrB: homoserine kinase 3 313 8.1E-109 T 05-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 K08M4_RS12410 979f36c6a4522b47f15f765786d8ff10 318 Hamap MF_00384 Homoserine kinase [thrB]. 3 313 30.144 T 05-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 K08M4_RS12410 979f36c6a4522b47f15f765786d8ff10 318 PRINTS PR00958 Homoserine kinase signature 143 156 9.5E-31 T 05-07-2017 K08M4_RS12410 979f36c6a4522b47f15f765786d8ff10 318 PRINTS PR00958 Homoserine kinase signature 181 198 9.5E-31 T 05-07-2017 K08M4_RS12410 979f36c6a4522b47f15f765786d8ff10 318 PRINTS PR00958 Homoserine kinase signature 10 25 9.5E-31 T 05-07-2017 K08M4_RS12410 979f36c6a4522b47f15f765786d8ff10 318 PRINTS PR00958 Homoserine kinase signature 260 275 9.5E-31 T 05-07-2017 K08M4_RS12410 979f36c6a4522b47f15f765786d8ff10 318 PRINTS PR00958 Homoserine kinase signature 103 118 9.5E-31 T 05-07-2017 K08M4_RS12410 979f36c6a4522b47f15f765786d8ff10 318 Pfam PF08544 GHMP kinases C terminal 220 291 3.2E-9 T 05-07-2017 IPR013750 GHMP kinase, C-terminal domain K08M4_RS12410 979f36c6a4522b47f15f765786d8ff10 318 Gene3D G3DSA:3.30.70.890 174 304 1.6E-41 T 05-07-2017 IPR013750 GHMP kinase, C-terminal domain K08M4_RS05640 8b8f93d674b54f1155b4b3e90e5ac7e2 149 Pfam PF06610 L-alanine exporter 8 142 1.6E-67 T 05-07-2017 IPR010574 L-alanine exporter AlaE GO:0016021|GO:0034639 K08M4_RS05640 8b8f93d674b54f1155b4b3e90e5ac7e2 149 Hamap MF_00914 L-alanine exporter AlaE [alaE]. 2 145 31.082 T 05-07-2017 IPR010574 L-alanine exporter AlaE GO:0016021|GO:0034639 K08M4_RS05640 8b8f93d674b54f1155b4b3e90e5ac7e2 149 ProDom PD090021 MEMBRANE YGAW TRANSMEMBRANE INNER VV2263 Y3636 VC1828 VP1070 15 142 2.0E-62 T 05-07-2017 IPR010574 L-alanine exporter AlaE GO:0016021|GO:0034639 K08M4_RS07520 b1b9d842ff581a9a11f1c3cc5191f6b5 229 Pfam PF11748 Protein of unknown function (DUF3306) 4 134 5.9E-26 T 05-07-2017 IPR021735 Protein of unknown function DUF3306 K08M4_RS06165 f0f6bdd8150451a89579ee70f581a721 308 Pfam PF00491 Arginase family 33 297 1.9E-88 T 05-07-2017 IPR006035 Ureohydrolase GO:0046872 K08M4_RS06165 f0f6bdd8150451a89579ee70f581a721 308 TIGRFAM TIGR01230 agmatinase: agmatinase 23 299 5.9E-93 T 05-07-2017 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 K08M4_RS06165 f0f6bdd8150451a89579ee70f581a721 308 Gene3D G3DSA:3.40.800.10 11 303 2.6E-102 T 05-07-2017 IPR023696 Ureohydrolase domain K08M4_RS06165 f0f6bdd8150451a89579ee70f581a721 308 SUPERFAMILY SSF52768 12 303 1.08E-95 T 05-07-2017 K08M4_RS06165 f0f6bdd8150451a89579ee70f581a721 308 ProSitePatterns PS01053 Arginase family signature. 229 250 - T 05-07-2017 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 K08M4_RS06165 f0f6bdd8150451a89579ee70f581a721 308 PIRSF PIRSF036979 11 305 9.6E-96 T 05-07-2017 IPR006035 Ureohydrolase GO:0046872 K08M4_RS07390 e99b63b3705c69f555c3749f6124e241 278 PRINTS PR01021 OMPA domain signature 210 226 1.3E-6 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS07390 e99b63b3705c69f555c3749f6124e241 278 PRINTS PR01021 OMPA domain signature 165 187 1.3E-6 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS07390 e99b63b3705c69f555c3749f6124e241 278 PRINTS PR01021 OMPA domain signature 195 210 1.3E-6 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS07390 e99b63b3705c69f555c3749f6124e241 278 Pfam PF00691 OmpA family 165 259 1.7E-19 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS07390 e99b63b3705c69f555c3749f6124e241 278 SUPERFAMILY SSF103088 153 265 2.35E-26 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS07390 e99b63b3705c69f555c3749f6124e241 278 Gene3D G3DSA:3.30.1330.60 162 268 1.8E-24 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS08875 54137ce14b04150b7e96655324b15d79 324 Gene3D G3DSA:1.10.443.10 106 309 3.5E-46 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS08875 54137ce14b04150b7e96655324b15d79 324 TIGRFAM TIGR02249 integrase_gron: integron integrase 6 320 3.8E-137 T 05-07-2017 IPR011946 Integrase, integron-type GO:0003677|GO:0006310|GO:0015074 K08M4_RS08875 54137ce14b04150b7e96655324b15d79 324 SUPERFAMILY SSF56349 217 308 1.47E-45 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS08875 54137ce14b04150b7e96655324b15d79 324 SUPERFAMILY SSF56349 8 190 1.47E-45 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS08875 54137ce14b04150b7e96655324b15d79 324 Gene3D G3DSA:1.10.150.130 8 81 3.2E-4 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal K08M4_RS08875 54137ce14b04150b7e96655324b15d79 324 Pfam PF00589 Phage integrase family 106 306 9.7E-38 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS08875 54137ce14b04150b7e96655324b15d79 324 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 8 88 5.8E-23 T 05-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 K08M4_RS13090 6323ba8666906f4848b5fdc9d6504821 489 Pfam PF00575 S1 RNA binding domain 38 109 1.5E-5 T 05-07-2017 IPR003029 S1 domain GO:0003676 K08M4_RS13090 6323ba8666906f4848b5fdc9d6504821 489 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 426 4.6E-171 T 05-07-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 K08M4_RS13090 6323ba8666906f4848b5fdc9d6504821 489 Gene3D G3DSA:2.40.50.140 30 128 2.7E-33 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS13090 6323ba8666906f4848b5fdc9d6504821 489 SUPERFAMILY SSF50249 39 128 1.72E-19 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS13090 6323ba8666906f4848b5fdc9d6504821 489 Pfam PF10150 Ribonuclease E/G family 124 393 7.9E-102 T 05-07-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 K08M4_RS13090 6323ba8666906f4848b5fdc9d6504821 489 SMART SM00316 37 122 8.0E-10 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS17595 cb0eeb0d9254ae7a2b545406fb5d0e54 294 Gene3D G3DSA:1.10.10.60 250 293 4.6E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS17595 cb0eeb0d9254ae7a2b545406fb5d0e54 294 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 264 279 2.5E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS17595 cb0eeb0d9254ae7a2b545406fb5d0e54 294 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 279 294 2.5E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS17595 cb0eeb0d9254ae7a2b545406fb5d0e54 294 Gene3D G3DSA:1.10.10.60 192 249 2.8E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS17595 cb0eeb0d9254ae7a2b545406fb5d0e54 294 Pfam PF12833 Helix-turn-helix domain 218 293 2.8E-20 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS17595 cb0eeb0d9254ae7a2b545406fb5d0e54 294 SMART SM00342 212 294 6.4E-23 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS17595 cb0eeb0d9254ae7a2b545406fb5d0e54 294 Pfam PF06719 AraC-type transcriptional regulator N-terminus 28 183 2.0E-33 T 05-07-2017 IPR009594 Transcription regulator HTH, AraC, N-terminal K08M4_RS17595 cb0eeb0d9254ae7a2b545406fb5d0e54 294 SUPERFAMILY SSF46689 195 246 1.53E-8 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS17595 cb0eeb0d9254ae7a2b545406fb5d0e54 294 SUPERFAMILY SSF46689 248 293 1.43E-10 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS17595 cb0eeb0d9254ae7a2b545406fb5d0e54 294 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 249 291 - T 05-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 K08M4_RS09940 0231f962f1537ea916a21e6ff0fda045 365 SUPERFAMILY SSF51395 3 363 1.57E-124 T 05-07-2017 K08M4_RS09940 0231f962f1537ea916a21e6ff0fda045 365 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 341 7.7E-99 T 05-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 K08M4_RS09940 0231f962f1537ea916a21e6ff0fda045 365 Gene3D G3DSA:3.20.20.70 2 362 6.6E-134 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS09450 f509a263e0f5c0f8633ae18dd48e3852 244 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 3 232 8.8E-103 T 05-07-2017 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 K08M4_RS09450 f509a263e0f5c0f8633ae18dd48e3852 244 Gene3D G3DSA:3.60.21.10 173 207 1.1E-22 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS09450 f509a263e0f5c0f8633ae18dd48e3852 244 Gene3D G3DSA:3.60.21.10 1 125 1.1E-22 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS09450 f509a263e0f5c0f8633ae18dd48e3852 244 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 204 2.1E-9 T 05-07-2017 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 K08M4_RS09450 f509a263e0f5c0f8633ae18dd48e3852 244 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 241 113.992 T 05-07-2017 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 K08M4_RS09450 f509a263e0f5c0f8633ae18dd48e3852 244 SUPERFAMILY SSF56300 1 223 1.82E-29 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS16315 2f8a4f3749b9b298c03fa8f415913a45 99 Pfam PF07383 Protein of unknown function (DUF1496) 43 94 7.1E-23 T 05-07-2017 IPR009971 Protein of unknown function DUF1496 K08M4_RS05265 b0839852940ed210061421bc19c3d2be 513 Pfam PF11840 Protein of unknown function (DUF3360) 10 513 6.1E-265 T 05-07-2017 IPR021794 Protein of unknown function DUF3360 K08M4_RS18780 93bf7eb56d409434415e71703a83c9fb 485 Gene3D G3DSA:3.30.870.10 42 230 1.6E-31 T 05-07-2017 K08M4_RS18780 93bf7eb56d409434415e71703a83c9fb 485 Gene3D G3DSA:3.30.870.10 260 434 7.7E-22 T 05-07-2017 K08M4_RS18780 93bf7eb56d409434415e71703a83c9fb 485 SMART SM00155 152 179 0.51 T 05-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 K08M4_RS18780 93bf7eb56d409434415e71703a83c9fb 485 SMART SM00155 380 407 4.9E-7 T 05-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 K08M4_RS18780 93bf7eb56d409434415e71703a83c9fb 485 Pfam PF13091 PLD-like domain 59 211 1.4E-13 T 05-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 K08M4_RS18780 93bf7eb56d409434415e71703a83c9fb 485 Pfam PF13091 PLD-like domain 302 432 1.1E-15 T 05-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 K08M4_RS18780 93bf7eb56d409434415e71703a83c9fb 485 SUPERFAMILY SSF56024 306 438 4.04E-20 T 05-07-2017 K08M4_RS18780 93bf7eb56d409434415e71703a83c9fb 485 SUPERFAMILY SSF56024 43 222 1.92E-33 T 05-07-2017 K08M4_RS19835 3194317bf600623543b605c16fc152c3 348 SUPERFAMILY SSF55073 200 343 1.02E-32 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS19835 3194317bf600623543b605c16fc152c3 348 Gene3D G3DSA:3.30.70.270 197 343 4.6E-36 T 05-07-2017 K08M4_RS19835 3194317bf600623543b605c16fc152c3 348 Pfam PF00990 Diguanylate cyclase, GGDEF domain 195 339 8.2E-31 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS19835 3194317bf600623543b605c16fc152c3 348 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 191 343 1.5E-31 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS19835 3194317bf600623543b605c16fc152c3 348 SMART SM00267 184 344 1.4E-35 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS18445 1d930f2e972690461f02e108007cffd5 128 SUPERFAMILY SSF101756 36 128 1.44E-20 T 05-07-2017 IPR005220 Bacterial OB-fold K08M4_RS18445 1d930f2e972690461f02e108007cffd5 128 Gene3D G3DSA:2.40.50.200 33 128 1.3E-21 T 05-07-2017 IPR005220 Bacterial OB-fold K08M4_RS18445 1d930f2e972690461f02e108007cffd5 128 Pfam PF04076 Bacterial OB fold (BOF) protein 41 126 1.3E-9 T 05-07-2017 IPR005220 Bacterial OB-fold K08M4_RS02125 05ada26696b2387f12665e5ec024aaf8 395 Pfam PF06969 HemN C-terminal domain 317 378 3.9E-9 T 05-07-2017 IPR010723 HemN, C-terminal K08M4_RS02125 05ada26696b2387f12665e5ec024aaf8 395 Gene3D G3DSA:1.10.10.10 333 388 5.2E-5 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS02125 05ada26696b2387f12665e5ec024aaf8 395 Pfam PF04055 Radical SAM superfamily 15 184 9.3E-18 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS02125 05ada26696b2387f12665e5ec024aaf8 395 SMART SM00729 10 231 1.1E-53 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 K08M4_RS02125 05ada26696b2387f12665e5ec024aaf8 395 SUPERFAMILY SSF102114 6 390 9.16E-112 T 05-07-2017 K08M4_RS02125 05ada26696b2387f12665e5ec024aaf8 395 Gene3D G3DSA:3.80.30.20 11 245 6.1E-29 T 05-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe K08M4_RS02125 05ada26696b2387f12665e5ec024aaf8 395 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 11 382 4.2E-136 T 05-07-2017 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 K08M4_RS05950 aadb59c65c9c6bb53abc7b01f557fbf7 274 Pfam PF10977 Protein of unknown function (DUF2797) 38 270 7.8E-96 T 05-07-2017 IPR021246 Protein of unknown function DUF2797 K08M4_RS11505 ce3a26916c30758c793993b457a32401 383 Pfam PF08468 Methyltransferase small domain N-terminal 47 160 1.1E-5 T 05-07-2017 IPR013675 Methyltransferase small, N-terminal GO:0006364|GO:0008990 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS11505 ce3a26916c30758c793993b457a32401 383 PIRSF PIRSF037565 1 377 1.5E-166 T 05-07-2017 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS11505 ce3a26916c30758c793993b457a32401 383 Pfam PF05175 Methyltransferase small domain 200 373 1.5E-51 T 05-07-2017 IPR007848 Methyltransferase small domain GO:0008168 K08M4_RS11505 ce3a26916c30758c793993b457a32401 383 Hamap MF_01859 Ribosomal RNA large subunit methyltransferase G [rlmG]. 2 376 48.243 T 05-07-2017 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 K08M4_RS11505 ce3a26916c30758c793993b457a32401 383 Gene3D G3DSA:3.40.50.150 194 372 7.6E-24 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS11505 ce3a26916c30758c793993b457a32401 383 SUPERFAMILY SSF53335 188 350 1.88E-27 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS12595 68bc2d4cad592f32047cbfcb6baa18e3 495 Gene3D G3DSA:3.90.190.20 343 485 4.0E-53 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS12595 68bc2d4cad592f32047cbfcb6baa18e3 495 SUPERFAMILY SSF63418 6 108 8.63E-22 T 05-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 K08M4_RS12595 68bc2d4cad592f32047cbfcb6baa18e3 495 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 25 491 4.6E-171 T 05-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 K08M4_RS12595 68bc2d4cad592f32047cbfcb6baa18e3 495 Gene3D G3DSA:3.40.1390.10 20 108 5.9E-27 T 05-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 K08M4_RS12595 68bc2d4cad592f32047cbfcb6baa18e3 495 Pfam PF02875 Mur ligase family, glutamate ligase domain 341 423 6.8E-21 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS12595 68bc2d4cad592f32047cbfcb6baa18e3 495 Gene3D G3DSA:3.40.1190.10 109 342 5.7E-78 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS12595 68bc2d4cad592f32047cbfcb6baa18e3 495 SUPERFAMILY SSF53244 339 491 2.75E-48 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS12595 68bc2d4cad592f32047cbfcb6baa18e3 495 Pfam PF01225 Mur ligase family, catalytic domain 28 105 4.2E-10 T 05-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 K08M4_RS12595 68bc2d4cad592f32047cbfcb6baa18e3 495 SUPERFAMILY SSF53623 109 338 3.92E-74 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS12595 68bc2d4cad592f32047cbfcb6baa18e3 495 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 5 491 34.21 T 05-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 K08M4_RS12595 68bc2d4cad592f32047cbfcb6baa18e3 495 Pfam PF08245 Mur ligase middle domain 117 318 8.1E-52 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS09095 00136a17aabc201c11b54aee61453737 247 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 20 246 38.039 T 05-07-2017 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 K08M4_RS09095 00136a17aabc201c11b54aee61453737 247 Gene3D G3DSA:3.40.50.150 34 236 9.5E-47 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS09095 00136a17aabc201c11b54aee61453737 247 SUPERFAMILY SSF53335 26 226 1.72E-43 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS09095 00136a17aabc201c11b54aee61453737 247 Pfam PF13489 Methyltransferase domain 63 207 4.6E-23 T 05-07-2017 K08M4_RS09095 00136a17aabc201c11b54aee61453737 247 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 22 240 2.1E-87 T 05-07-2017 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 K08M4_RS21220 c9fb0bf93662ace27f5aba9ef1909e4f 337 SUPERFAMILY SSF47413 6 58 1.89E-13 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS21220 c9fb0bf93662ace27f5aba9ef1909e4f 337 Pfam PF13377 Periplasmic binding protein-like domain 175 332 1.8E-36 T 05-07-2017 K08M4_RS21220 c9fb0bf93662ace27f5aba9ef1909e4f 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 19 29 1.8E-5 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS21220 c9fb0bf93662ace27f5aba9ef1909e4f 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 9 19 1.8E-5 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS21220 c9fb0bf93662ace27f5aba9ef1909e4f 337 SUPERFAMILY SSF53822 67 333 6.48E-77 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS21220 c9fb0bf93662ace27f5aba9ef1909e4f 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 54 9.6E-17 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS21220 c9fb0bf93662ace27f5aba9ef1909e4f 337 SMART SM00354 7 77 4.6E-19 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS21220 c9fb0bf93662ace27f5aba9ef1909e4f 337 Gene3D G3DSA:3.40.50.2300 177 315 4.0E-53 T 05-07-2017 K08M4_RS21220 c9fb0bf93662ace27f5aba9ef1909e4f 337 Gene3D G3DSA:3.40.50.2300 60 176 9.0E-34 T 05-07-2017 K08M4_RS21220 c9fb0bf93662ace27f5aba9ef1909e4f 337 Gene3D G3DSA:1.10.260.40 8 59 3.9E-19 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS21220 c9fb0bf93662ace27f5aba9ef1909e4f 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 10 28 - T 05-07-2017 K08M4_RS10455 9e0ea56df0bc0ac28021e0715ec066f0 545 SUPERFAMILY SSF51412 96 394 3.94E-15 T 05-07-2017 K08M4_RS10455 9e0ea56df0bc0ac28021e0715ec066f0 545 Gene3D G3DSA:3.20.20.70 97 361 9.8E-15 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS10455 9e0ea56df0bc0ac28021e0715ec066f0 545 TIGRFAM TIGR02814 pfaD_fam: PfaD family protein 83 521 2.8E-214 T 05-07-2017 IPR014179 PfaD family protein KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 K08M4_RS17515 2fd81624097f6728c8f50f56da67a7d0 579 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 218 397 1.2E-31 T 05-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 K08M4_RS17515 2fd81624097f6728c8f50f56da67a7d0 579 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 116 324 3.6E-75 T 05-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain K08M4_RS17515 2fd81624097f6728c8f50f56da67a7d0 579 Gene3D G3DSA:2.40.50.100 139 167 2.1E-9 T 05-07-2017 K08M4_RS17515 2fd81624097f6728c8f50f56da67a7d0 579 Gene3D G3DSA:2.40.50.100 218 248 2.1E-9 T 05-07-2017 K08M4_RS17515 2fd81624097f6728c8f50f56da67a7d0 579 Pfam PF11604 Copper binding periplasmic protein CusF 424 489 1.2E-20 T 05-07-2017 IPR021647 Copper binding periplasmic protein CusF K08M4_RS17515 2fd81624097f6728c8f50f56da67a7d0 579 Pfam PF11604 Copper binding periplasmic protein CusF 504 570 9.3E-19 T 05-07-2017 IPR021647 Copper binding periplasmic protein CusF K08M4_RS17515 2fd81624097f6728c8f50f56da67a7d0 579 SUPERFAMILY SSF111369 139 329 9.15E-14 T 05-07-2017 K08M4_RS17265 aa67933655c35d2e898a0ef1d18cf017 421 Gene3D G3DSA:3.30.450.90 69 165 2.0E-36 T 05-07-2017 K08M4_RS17265 aa67933655c35d2e898a0ef1d18cf017 421 Gene3D G3DSA:3.40.50.300 170 409 2.3E-66 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17265 aa67933655c35d2e898a0ef1d18cf017 421 Pfam PF00437 Type II/IV secretion system protein 71 347 8.4E-86 T 05-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 K08M4_RS17265 aa67933655c35d2e898a0ef1d18cf017 421 SUPERFAMILY SSF52540 56 362 2.46E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00845 c7708ed1142c004a5091d88921d91d1a 264 ProSitePatterns PS00893 Nudix box signature. 164 185 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 K08M4_RS00845 c7708ed1142c004a5091d88921d91d1a 264 Gene3D G3DSA:3.90.79.10 97 256 2.3E-41 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS00845 c7708ed1142c004a5091d88921d91d1a 264 Hamap MF_00297 NADH pyrophosphatase [nudC]. 3 262 40.321 T 05-07-2017 IPR022925 NADH pyrophosphatase NudC GO:0000210 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 K08M4_RS00845 c7708ed1142c004a5091d88921d91d1a 264 Pfam PF00293 NUDIX domain 137 238 1.1E-18 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 K08M4_RS00845 c7708ed1142c004a5091d88921d91d1a 264 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 99 129 9.4E-10 T 05-07-2017 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 K08M4_RS00845 c7708ed1142c004a5091d88921d91d1a 264 SUPERFAMILY SSF55811 66 247 1.23E-44 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 Pfam PF16658 Class II release factor RF3, C-terminal domain 384 510 3.7E-46 T 05-07-2017 IPR032090 Peptide chain release factor 3, C-terminal K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 Pfam PF00009 Elongation factor Tu GTP binding domain 10 274 4.2E-46 T 05-07-2017 K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 145 5.2E-19 T 05-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 PRINTS PR00315 GTP-binding elongation factor signature 62 70 3.3E-10 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 PRINTS PR00315 GTP-binding elongation factor signature 134 143 3.3E-10 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 PRINTS PR00315 GTP-binding elongation factor signature 12 25 3.3E-10 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 PRINTS PR00315 GTP-binding elongation factor signature 82 92 3.3E-10 T 05-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 Gene3D G3DSA:3.30.70.870 392 460 3.3E-13 T 05-07-2017 K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 SUPERFAMILY SSF50447 259 390 1.57E-27 T 05-07-2017 IPR009000 Translation protein, beta-barrel domain K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 Gene3D G3DSA:2.40.30.10 290 391 6.5E-25 T 05-07-2017 K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 1 524 52.067 T 05-07-2017 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 4 526 3.3E-301 T 05-07-2017 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 SUPERFAMILY SSF54980 390 465 1.01E-16 T 05-07-2017 IPR009022 Elongation factor G, III-V domain K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 Pfam PF03144 Elongation factor Tu domain 2 311 377 2.1E-8 T 05-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 Gene3D G3DSA:3.40.50.300 4 280 2.4E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 SUPERFAMILY SSF52540 7 274 4.36E-85 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03200 bf4fa155a1416dbe05cda42e4b20154a 526 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 05-07-2017 IPR031157 Tr-type G domain, conserved site K08M4_RS13920 0c1334a3d1e637d935068edaa1e67dfd 295 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 8.6E-157 T 05-07-2017 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 K08M4_RS13920 0c1334a3d1e637d935068edaa1e67dfd 295 SUPERFAMILY SSF53448 1 286 2.7E-93 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS13920 0c1334a3d1e637d935068edaa1e67dfd 295 Pfam PF00483 Nucleotidyl transferase 2 238 1.3E-71 T 05-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 K08M4_RS13920 0c1334a3d1e637d935068edaa1e67dfd 295 Gene3D G3DSA:3.90.550.10 1 260 8.4E-68 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS05420 6129584cc393f25e8fa1232011d22db2 265 Gene3D G3DSA:3.40.50.1820 14 261 7.1E-43 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS05420 6129584cc393f25e8fa1232011d22db2 265 PRINTS PR00412 Epoxide hydrolase signature 205 221 4.6E-5 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 K08M4_RS05420 6129584cc393f25e8fa1232011d22db2 265 PRINTS PR00412 Epoxide hydrolase signature 24 42 4.6E-5 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 K08M4_RS05420 6129584cc393f25e8fa1232011d22db2 265 PRINTS PR00412 Epoxide hydrolase signature 237 259 4.6E-5 T 05-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 K08M4_RS05420 6129584cc393f25e8fa1232011d22db2 265 Pfam PF00561 alpha/beta hydrolase fold 19 121 2.7E-21 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS05420 6129584cc393f25e8fa1232011d22db2 265 SUPERFAMILY SSF53474 14 262 2.78E-43 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS15705 35be7fa6c36b36e1bb0eb069065cd46f 290 SUPERFAMILY SSF52151 3 271 5.49E-31 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 K08M4_RS02710 e5e96e4729f5a18c9730d7414fc52873 153 Pfam PF09335 SNARE associated Golgi protein 50 146 6.4E-11 T 05-07-2017 IPR032816 SNARE associated Golgi protein K08M4_RS06415 68b63febeff92b1d170fd9fa7bf8f1b7 628 SMART SM00304 296 350 1.6E-12 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS06415 68b63febeff92b1d170fd9fa7bf8f1b7 628 SMART SM00304 353 403 110.0 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS06415 68b63febeff92b1d170fd9fa7bf8f1b7 628 SUPERFAMILY SSF58104 318 627 6.41E-76 T 05-07-2017 K08M4_RS06415 68b63febeff92b1d170fd9fa7bf8f1b7 628 SMART SM00283 365 626 1.3E-72 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS06415 68b63febeff92b1d170fd9fa7bf8f1b7 628 Pfam PF00672 HAMP domain 277 347 9.0E-13 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS06415 68b63febeff92b1d170fd9fa7bf8f1b7 628 Gene3D G3DSA:3.30.450.20 162 269 2.3E-14 T 05-07-2017 K08M4_RS06415 68b63febeff92b1d170fd9fa7bf8f1b7 628 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 432 625 3.1E-45 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS06415 68b63febeff92b1d170fd9fa7bf8f1b7 628 Gene3D G3DSA:1.10.287.950 380 596 1.4E-55 T 05-07-2017 K08M4_RS06415 68b63febeff92b1d170fd9fa7bf8f1b7 628 Gene3D G3DSA:3.30.450.20 69 161 5.7E-10 T 05-07-2017 K08M4_RS06415 68b63febeff92b1d170fd9fa7bf8f1b7 628 Pfam PF02743 Cache domain 42 258 1.1E-22 T 05-07-2017 IPR033479 Double Cache domain 1 K08M4_RS20775 15bfbb43213032bfaee10f4d790d0de0 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 256 3.9E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS20775 15bfbb43213032bfaee10f4d790d0de0 291 SUPERFAMILY SSF161098 63 252 3.14E-21 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS20775 15bfbb43213032bfaee10f4d790d0de0 291 Gene3D G3DSA:1.10.3720.10 59 258 3.4E-21 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS03260 bd7a37c8ab95411fac51a5f8ff59e253 782 SUPERFAMILY SSF141371 466 555 3.4E-6 T 05-07-2017 K08M4_RS03260 bd7a37c8ab95411fac51a5f8ff59e253 782 Gene3D G3DSA:2.40.10.220 468 542 3.3E-4 T 05-07-2017 K08M4_RS03260 bd7a37c8ab95411fac51a5f8ff59e253 782 Pfam PF07238 PilZ domain 470 561 1.3E-10 T 05-07-2017 IPR009875 PilZ domain GO:0035438 K08M4_RS03260 bd7a37c8ab95411fac51a5f8ff59e253 782 Pfam PF07238 PilZ domain 145 233 1.4E-9 T 05-07-2017 IPR009875 PilZ domain GO:0035438 K08M4_RS03260 bd7a37c8ab95411fac51a5f8ff59e253 782 SUPERFAMILY SSF141371 143 200 6.47E-5 T 05-07-2017 K08M4_RS04350 163e9b37dbf1c5746b28b09186e2e0d8 191 Pfam PF04542 Sigma-70 region 2 33 99 2.5E-17 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04350 163e9b37dbf1c5746b28b09186e2e0d8 191 Pfam PF08281 Sigma-70, region 4 123 175 5.4E-11 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04350 163e9b37dbf1c5746b28b09186e2e0d8 191 Gene3D G3DSA:1.10.1740.10 26 120 7.3E-23 T 05-07-2017 K08M4_RS04350 163e9b37dbf1c5746b28b09186e2e0d8 191 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 55 86 - T 05-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04350 163e9b37dbf1c5746b28b09186e2e0d8 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 179 1.4E-20 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04350 163e9b37dbf1c5746b28b09186e2e0d8 191 SUPERFAMILY SSF88659 120 180 3.71E-12 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS04350 163e9b37dbf1c5746b28b09186e2e0d8 191 Gene3D G3DSA:1.10.10.10 121 180 7.4E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS04350 163e9b37dbf1c5746b28b09186e2e0d8 191 SUPERFAMILY SSF88946 26 111 3.37E-21 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS07800 99a830e513a150f2e4b8f37d92cd4c4e 184 PIRSF PIRSF010252 1 180 1.3E-68 T 05-07-2017 IPR009809 Cell division protein ZapC K08M4_RS07800 99a830e513a150f2e4b8f37d92cd4c4e 184 Pfam PF07126 Cell-division protein ZapC 2 170 1.5E-64 T 05-07-2017 IPR009809 Cell division protein ZapC K08M4_RS07800 99a830e513a150f2e4b8f37d92cd4c4e 184 Hamap MF_00906 Cell division protein ZapC [zapC]. 2 179 35.551 T 05-07-2017 IPR009809 Cell division protein ZapC K08M4_RS05565 db2e6c9f0e1a3ea1e83a38b18ddb83a9 147 TIGRFAM TIGR02801 tolR: protein TolR 12 144 1.0E-37 T 05-07-2017 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 K08M4_RS05565 db2e6c9f0e1a3ea1e83a38b18ddb83a9 147 Pfam PF02472 Biopolymer transport protein ExbD/TolR 9 144 1.2E-24 T 05-07-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 K08M4_RS21005 c4c9ab2c03af834b9ee44900c6cd273c 474 Gene3D G3DSA:3.40.50.2300 376 472 5.6E-36 T 05-07-2017 K08M4_RS21005 c4c9ab2c03af834b9ee44900c6cd273c 474 SUPERFAMILY SSF52794 380 471 6.98E-29 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS21005 c4c9ab2c03af834b9ee44900c6cd273c 474 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 21 351 2.4E-76 T 05-07-2017 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 K08M4_RS21005 c4c9ab2c03af834b9ee44900c6cd273c 474 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 383 468 8.4E-16 T 05-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 K08M4_RS21005 c4c9ab2c03af834b9ee44900c6cd273c 474 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 382 466 1.1E-32 T 05-07-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 K08M4_RS21230 44c9cf57009d97a644014e60a5a52a0f 315 Pfam PF01263 Aldose 1-epimerase 14 304 1.4E-36 T 05-07-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 K08M4_RS21230 44c9cf57009d97a644014e60a5a52a0f 315 SUPERFAMILY SSF74650 14 308 2.2E-48 T 05-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 K08M4_RS21230 44c9cf57009d97a644014e60a5a52a0f 315 Gene3D G3DSA:2.70.98.10 11 305 1.2E-35 T 05-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 K08M4_RS20600 86720656929a359b02116f8db3449899 127 Gene3D G3DSA:3.30.1330.40 2 125 2.5E-49 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS20600 86720656929a359b02116f8db3449899 127 Pfam PF01042 Endoribonuclease L-PSP 7 125 5.9E-42 T 05-07-2017 IPR006175 YjgF/YER057c/UK114 family K08M4_RS20600 86720656929a359b02116f8db3449899 127 SUPERFAMILY SSF55298 2 126 1.34E-45 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS20600 86720656929a359b02116f8db3449899 127 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 2 125 6.5E-50 T 05-07-2017 IPR006056 RidA family K08M4_RS15750 4e769e8a7b911a59777f87cb4a4cef7f 297 Pfam PF07148 Maltose operon periplasmic protein precursor (MalM) 71 201 2.7E-42 T 05-07-2017 IPR010794 Maltose operon periplasmic GO:0008643|GO:0042597 K08M4_RS13240 ed20fe9b91caa2f584f529e41091edb7 426 Pfam PF00999 Sodium/hydrogen exchanger family 19 416 6.3E-54 T 05-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 K08M4_RS08500 11d34c591b4b5ab8d233270a04b25351 453 SUPERFAMILY SSF143548 16 157 3.4E-43 T 05-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 K08M4_RS08500 11d34c591b4b5ab8d233270a04b25351 453 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 2 451 6.9E-225 T 05-07-2017 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 K08M4_RS08500 11d34c591b4b5ab8d233270a04b25351 453 Gene3D G3DSA:3.30.1330.90 10 157 3.8E-51 T 05-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 K08M4_RS08500 11d34c591b4b5ab8d233270a04b25351 453 Pfam PF03315 Serine dehydratase beta chain 3 155 1.6E-53 T 05-07-2017 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 K08M4_RS08500 11d34c591b4b5ab8d233270a04b25351 453 Pfam PF03313 Serine dehydratase alpha chain 184 448 9.7E-98 T 05-07-2017 IPR005130 Serine dehydratase-like, alpha subunit K08M4_RS18545 12a546dbc48f55d671e213ab4345f9b1 452 Pfam PF13518 Helix-turn-helix domain 12 62 1.8E-6 T 05-07-2017 K08M4_RS18545 12a546dbc48f55d671e213ab4345f9b1 452 SUPERFAMILY SSF53098 132 293 1.08E-17 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS18545 12a546dbc48f55d671e213ab4345f9b1 452 Gene3D G3DSA:3.30.420.10 131 291 4.4E-18 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS18545 12a546dbc48f55d671e213ab4345f9b1 452 SUPERFAMILY SSF46689 10 115 3.4E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 PRINTS PR01900 YidC translocation/secretion protein signature 335 351 7.6E-25 T 05-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 PRINTS PR01900 YidC translocation/secretion protein signature 484 508 7.6E-25 T 05-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 PRINTS PR01900 YidC translocation/secretion protein signature 464 479 7.6E-25 T 05-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 Pfam PF02096 60Kd inner membrane protein 350 529 2.0E-63 T 05-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 349 529 1.7E-73 T 05-07-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 Pfam PF14849 YidC periplasmic domain 64 338 6.6E-84 T 05-07-2017 IPR028053 Membrane insertase YidC, N-terminal K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 3 347 2.3E-108 T 05-07-2017 IPR028053 Membrane insertase YidC, N-terminal K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 PRINTS PR00701 60kDa inner membrane protein signature 248 263 1.1E-99 T 05-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 PRINTS PR00701 60kDa inner membrane protein signature 495 518 1.1E-99 T 05-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 PRINTS PR00701 60kDa inner membrane protein signature 320 340 1.1E-99 T 05-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 PRINTS PR00701 60kDa inner membrane protein signature 458 480 1.1E-99 T 05-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 PRINTS PR00701 60kDa inner membrane protein signature 70 91 1.1E-99 T 05-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 PRINTS PR00701 60kDa inner membrane protein signature 411 434 1.1E-99 T 05-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 PRINTS PR00701 60kDa inner membrane protein signature 2 23 1.1E-99 T 05-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 PRINTS PR00701 60kDa inner membrane protein signature 160 180 1.1E-99 T 05-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 PRINTS PR00701 60kDa inner membrane protein signature 213 231 1.1E-99 T 05-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 K08M4_RS14985 0772c34975f3ee67cb6c8565cf33f646 539 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 531 25.554 T 05-07-2017 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 K08M4_RS10105 6cf54a645ccc5291318237e496f5891a 294 Gene3D G3DSA:3.40.190.10 183 262 3.4E-12 T 05-07-2017 K08M4_RS10105 6cf54a645ccc5291318237e496f5891a 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 4.9E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS10105 6cf54a645ccc5291318237e496f5891a 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 4.9E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS10105 6cf54a645ccc5291318237e496f5891a 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 4.9E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS10105 6cf54a645ccc5291318237e496f5891a 294 SUPERFAMILY SSF53850 92 292 1.19E-27 T 05-07-2017 K08M4_RS10105 6cf54a645ccc5291318237e496f5891a 294 Gene3D G3DSA:3.40.190.10 97 182 1.1E-26 T 05-07-2017 K08M4_RS10105 6cf54a645ccc5291318237e496f5891a 294 Pfam PF03466 LysR substrate binding domain 93 293 6.5E-26 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS10105 6cf54a645ccc5291318237e496f5891a 294 Gene3D G3DSA:1.10.10.10 7 85 1.2E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS10105 6cf54a645ccc5291318237e496f5891a 294 SUPERFAMILY SSF46785 9 80 2.03E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS10105 6cf54a645ccc5291318237e496f5891a 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 70 1.1E-18 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS07975 0b6f55b714b583bca85f51bf56358013 216 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 1 216 32.334 T 05-07-2017 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 K08M4_RS07975 0b6f55b714b583bca85f51bf56358013 216 Pfam PF13394 4Fe-4S single cluster domain 17 121 3.1E-11 T 05-07-2017 K08M4_RS07975 0b6f55b714b583bca85f51bf56358013 216 TIGRFAM TIGR04322 rSAM_QueE_Ecoli: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 2 215 3.7E-108 T 05-07-2017 IPR027609 Putative 7-carboxy-7-deazaguanine synthase QueE, Proteobacteria KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 K08M4_RS07975 0b6f55b714b583bca85f51bf56358013 216 PIRSF PIRSF000370 1 216 2.9E-64 T 05-07-2017 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 K08M4_RS07975 0b6f55b714b583bca85f51bf56358013 216 Gene3D G3DSA:3.20.20.70 23 115 2.7E-6 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS07975 0b6f55b714b583bca85f51bf56358013 216 SUPERFAMILY SSF102114 19 121 2.35E-6 T 05-07-2017 K08M4_RS07975 0b6f55b714b583bca85f51bf56358013 216 Pfam PF04055 Radical SAM superfamily 19 117 1.0E-7 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS01295 00c874d056413fe81d07fdbf5d5421c7 286 TIGRFAM TIGR00571 dam: DNA adenine methylase 5 268 1.1E-91 T 05-07-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 K08M4_RS01295 00c874d056413fe81d07fdbf5d5421c7 286 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 178 184 - T 05-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 K08M4_RS01295 00c874d056413fe81d07fdbf5d5421c7 286 Gene3D G3DSA:3.40.50.150 160 267 5.1E-52 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS01295 00c874d056413fe81d07fdbf5d5421c7 286 Gene3D G3DSA:3.40.50.150 1 59 5.1E-52 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS01295 00c874d056413fe81d07fdbf5d5421c7 286 PIRSF PIRSF000398 1 275 3.3E-70 T 05-07-2017 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 K08M4_RS01295 00c874d056413fe81d07fdbf5d5421c7 286 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 175 187 1.3E-17 T 05-07-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 K08M4_RS01295 00c874d056413fe81d07fdbf5d5421c7 286 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 50 63 1.3E-17 T 05-07-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 K08M4_RS01295 00c874d056413fe81d07fdbf5d5421c7 286 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 10 26 1.3E-17 T 05-07-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 K08M4_RS01295 00c874d056413fe81d07fdbf5d5421c7 286 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 31 45 1.3E-17 T 05-07-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 K08M4_RS01295 00c874d056413fe81d07fdbf5d5421c7 286 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 10 252 2.8E-67 T 05-07-2017 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 K08M4_RS01295 00c874d056413fe81d07fdbf5d5421c7 286 Gene3D G3DSA:1.10.1020.10 60 156 1.2E-32 T 05-07-2017 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 K08M4_RS01295 00c874d056413fe81d07fdbf5d5421c7 286 SUPERFAMILY SSF53335 5 268 3.74E-74 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS05140 9d1d116dc387703b53ac7fdba756ae8e 338 Gene3D G3DSA:3.30.160.60 302 337 1.1E-18 T 05-07-2017 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 K08M4_RS05140 9d1d116dc387703b53ac7fdba756ae8e 338 Pfam PF02618 YceG-like family 43 328 3.0E-80 T 05-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like K08M4_RS05140 9d1d116dc387703b53ac7fdba756ae8e 338 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 3 336 2.8E-98 T 05-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like K08M4_RS05140 9d1d116dc387703b53ac7fdba756ae8e 338 Gene3D G3DSA:3.30.160.60 73 110 8.4E-16 T 05-07-2017 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 K08M4_RS06015 85763b116076ae54dd3a56058bffb17a 227 Pfam PF11813 Protein of unknown function (DUF3334) 4 227 2.6E-116 T 05-07-2017 IPR024513 Protein of unknown function DUF3334 K08M4_RS06015 85763b116076ae54dd3a56058bffb17a 227 Gene3D G3DSA:3.40.1550.10 17 173 3.9E-14 T 05-07-2017 IPR028976 CheC-like domain K08M4_RS06015 85763b116076ae54dd3a56058bffb17a 227 SUPERFAMILY SSF103039 10 173 6.15E-24 T 05-07-2017 IPR028976 CheC-like domain K08M4_RS08490 4e2f616f56f7026e758af38ae39358e7 199 Pfam PF00293 NUDIX domain 35 113 5.0E-11 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 K08M4_RS08490 4e2f616f56f7026e758af38ae39358e7 199 SUPERFAMILY SSF55811 33 187 2.98E-32 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS08490 4e2f616f56f7026e758af38ae39358e7 199 Gene3D G3DSA:3.90.79.10 29 194 1.2E-36 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS09925 692c8ef61fd8d3d48b76ccca941e110a 328 Gene3D G3DSA:1.20.970.10 23 80 1.4E-13 T 05-07-2017 K08M4_RS09925 692c8ef61fd8d3d48b76ccca941e110a 328 Gene3D G3DSA:3.40.1030.10 87 293 3.3E-30 T 05-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS09925 692c8ef61fd8d3d48b76ccca941e110a 328 Pfam PF02885 Glycosyl transferase family, helical bundle domain 18 77 1.2E-12 T 05-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS09925 692c8ef61fd8d3d48b76ccca941e110a 328 SUPERFAMILY SSF47648 18 80 4.45E-15 T 05-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS09925 692c8ef61fd8d3d48b76ccca941e110a 328 SUPERFAMILY SSF52418 82 323 3.92E-42 T 05-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 K08M4_RS14295 f85ec4488b0d5cad14d74aa49dd6711d 176 SUPERFAMILY SSF52540 4 168 9.02E-16 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14295 f85ec4488b0d5cad14d74aa49dd6711d 176 Pfam PF13521 AAA domain 4 164 2.3E-35 T 05-07-2017 K08M4_RS14295 f85ec4488b0d5cad14d74aa49dd6711d 176 Gene3D G3DSA:3.40.50.300 1 168 2.4E-27 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12750 09e7c73c58df270256cdda2c90cb009a 249 SUPERFAMILY SSF81324 9 209 1.21E-46 T 05-07-2017 K08M4_RS12750 09e7c73c58df270256cdda2c90cb009a 249 Pfam PF00520 Ion transport protein 14 210 2.7E-17 T 05-07-2017 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 K08M4_RS12750 09e7c73c58df270256cdda2c90cb009a 249 PRINTS PR00169 Potassium channel signature 153 175 1.0E-8 T 05-07-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 K08M4_RS12750 09e7c73c58df270256cdda2c90cb009a 249 PRINTS PR00169 Potassium channel signature 182 208 1.0E-8 T 05-07-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 K08M4_RS12750 09e7c73c58df270256cdda2c90cb009a 249 PRINTS PR00169 Potassium channel signature 122 145 1.0E-8 T 05-07-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 K08M4_RS12750 09e7c73c58df270256cdda2c90cb009a 249 Gene3D G3DSA:1.20.5.110 174 214 1.8E-15 T 05-07-2017 K08M4_RS12750 09e7c73c58df270256cdda2c90cb009a 249 Gene3D G3DSA:1.20.120.350 11 124 3.0E-15 T 05-07-2017 IPR027359 Voltage-dependent channel, four helix bundle domain K08M4_RS12750 09e7c73c58df270256cdda2c90cb009a 249 Gene3D G3DSA:1.10.287.70 125 172 1.4E-15 T 05-07-2017 K08M4_RS07990 5fd6abb3f0488812144ed74f2c4a4056 159 Gene3D G3DSA:3.40.630.30 1 153 3.0E-27 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS07990 5fd6abb3f0488812144ed74f2c4a4056 159 Pfam PF13673 Acetyltransferase (GNAT) domain 31 148 4.1E-12 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS07990 5fd6abb3f0488812144ed74f2c4a4056 159 SUPERFAMILY SSF55729 1 148 4.46E-26 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS04085 c397acb2968d679898af49e7cde75383 626 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 5 338 1.6E-58 T 05-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 K08M4_RS04085 c397acb2968d679898af49e7cde75383 626 SUPERFAMILY SSF64518 169 397 1.23E-24 T 05-07-2017 K08M4_RS04085 c397acb2968d679898af49e7cde75383 626 SUPERFAMILY SSF64518 489 624 1.23E-24 T 05-07-2017 K08M4_RS04085 c397acb2968d679898af49e7cde75383 626 Pfam PF00460 Flagella basal body rod protein 15 35 2.2E-4 T 05-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 K08M4_RS04085 c397acb2968d679898af49e7cde75383 626 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 580 624 1.8E-9 T 05-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain K08M4_RS04085 c397acb2968d679898af49e7cde75383 626 PRINTS PR01005 Flagellar hook-associated protein signature 12 35 1.2E-9 T 05-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 K08M4_RS04085 c397acb2968d679898af49e7cde75383 626 PRINTS PR01005 Flagellar hook-associated protein signature 158 182 1.2E-9 T 05-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 K08M4_RS04085 c397acb2968d679898af49e7cde75383 626 PRINTS PR01005 Flagellar hook-associated protein signature 408 425 1.2E-9 T 05-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 K08M4_RS04085 c397acb2968d679898af49e7cde75383 626 PRINTS PR01005 Flagellar hook-associated protein signature 50 72 1.2E-9 T 05-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 K08M4_RS04085 c397acb2968d679898af49e7cde75383 626 PRINTS PR01005 Flagellar hook-associated protein signature 360 382 1.2E-9 T 05-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 K08M4_RS09380 2a4fd0b4a210ab87159a207189d91e6c 301 SMART SM01131 178 300 5.9E-34 T 05-07-2017 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1 K08M4_RS09380 2a4fd0b4a210ab87159a207189d91e6c 301 Gene3D G3DSA:3.90.1640.10 2 179 5.2E-56 T 05-07-2017 K08M4_RS09380 2a4fd0b4a210ab87159a207189d91e6c 301 SUPERFAMILY SSF64182 1 298 1.44E-66 T 05-07-2017 K08M4_RS09380 2a4fd0b4a210ab87159a207189d91e6c 301 Pfam PF02833 DHHA2 domain 180 297 6.1E-16 T 05-07-2017 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1 K08M4_RS09380 2a4fd0b4a210ab87159a207189d91e6c 301 Pfam PF01368 DHH family 2 142 2.5E-21 T 05-07-2017 IPR001667 DDH domain K08M4_RS13455 0d535495c8027c2dbf7f09af6871915f 302 Pfam PF04338 Protein of unknown function, DUF481 87 302 8.4E-53 T 05-07-2017 IPR007433 Protein of unknown function DUF481 K08M4_RS13455 0d535495c8027c2dbf7f09af6871915f 302 SUPERFAMILY SSF56935 213 258 1.03E-5 T 05-07-2017 K08M4_RS13455 0d535495c8027c2dbf7f09af6871915f 302 SUPERFAMILY SSF56935 85 182 1.03E-5 T 05-07-2017 K08M4_RS13455 0d535495c8027c2dbf7f09af6871915f 302 Gene3D G3DSA:2.40.160.10 87 183 3.6E-5 T 05-07-2017 IPR023614 Porin domain K08M4_RS18535 85e4d01a996c4b4e3f301ea89caee5b0 429 Gene3D G3DSA:3.30.70.270 271 426 2.8E-40 T 05-07-2017 K08M4_RS18535 85e4d01a996c4b4e3f301ea89caee5b0 429 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 266 426 7.3E-34 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS18535 85e4d01a996c4b4e3f301ea89caee5b0 429 Pfam PF00990 Diguanylate cyclase, GGDEF domain 269 424 5.2E-32 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS18535 85e4d01a996c4b4e3f301ea89caee5b0 429 SUPERFAMILY SSF55073 274 426 1.41E-34 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS18535 85e4d01a996c4b4e3f301ea89caee5b0 429 SMART SM00267 258 428 1.5E-31 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS03190 f8eb585394d210b2226abd34bae17aac 132 Gene3D G3DSA:3.40.50.10220 34 132 1.3E-36 T 05-07-2017 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS03190 f8eb585394d210b2226abd34bae17aac 132 SUPERFAMILY SSF102220 35 132 5.1E-25 T 05-07-2017 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS03190 f8eb585394d210b2226abd34bae17aac 132 ProDom PD032475 DNA POLYMERASE PSI SUBUNIT III TRANSFERASE NUCLEOTIDYLTRANSFERASE III 3D-STRUCTURE DNA-DIRECTED 37 128 4.0E-5 T 05-07-2017 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS03190 f8eb585394d210b2226abd34bae17aac 132 PIRSF PIRSF029225 2 132 1.6E-39 T 05-07-2017 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS03190 f8eb585394d210b2226abd34bae17aac 132 Pfam PF03603 DNA polymerase III psi subunit 4 129 3.3E-37 T 05-07-2017 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS17035 a2e900e1d95ffcdd617bbb883fc33a36 248 Gene3D G3DSA:3.20.20.140 3 237 3.0E-53 T 05-07-2017 K08M4_RS17035 a2e900e1d95ffcdd617bbb883fc33a36 248 SUPERFAMILY SSF89550 4 243 5.23E-58 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 K08M4_RS17035 a2e900e1d95ffcdd617bbb883fc33a36 248 SMART SM00481 5 79 3.5E-5 T 05-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 K08M4_RS17035 a2e900e1d95ffcdd617bbb883fc33a36 248 Hamap MF_01561 Probable phosphatase YcdX [ycdX]. 2 245 51.696 T 05-07-2017 IPR023710 Probable phosphatase YcdX GO:0008270 K08M4_RS06725 b7bd287ab4b1d583f09ee93b3feeb0b8 63 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 7 56 6.8E-19 T 05-07-2017 IPR010260 Prophage CP4-57 regulatory protein (AlpA) K08M4_RS19875 1e11979bc67bb66b0903c880d26605c0 121 SUPERFAMILY SSF54593 4 112 1.93E-19 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS19875 1e11979bc67bb66b0903c880d26605c0 121 Gene3D G3DSA:3.10.180.10 5 112 7.3E-15 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS11110 a8df09b37215afa33c014083b27ba402 252 PIRSF PIRSF005457 1 252 3.5E-98 T 05-07-2017 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 K08M4_RS11110 a8df09b37215afa33c014083b27ba402 252 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 2 252 44.517 T 05-07-2017 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 K08M4_RS11110 a8df09b37215afa33c014083b27ba402 252 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 167 252 5.7E-26 T 05-07-2017 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 K08M4_RS11110 a8df09b37215afa33c014083b27ba402 252 Pfam PF00753 Metallo-beta-lactamase superfamily 14 163 1.9E-17 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS11110 a8df09b37215afa33c014083b27ba402 252 Gene3D G3DSA:3.60.15.10 4 252 7.5E-85 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS11110 a8df09b37215afa33c014083b27ba402 252 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 4 252 1.5E-102 T 05-07-2017 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 K08M4_RS11110 a8df09b37215afa33c014083b27ba402 252 SMART SM00849 12 166 2.5E-33 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS11110 a8df09b37215afa33c014083b27ba402 252 SUPERFAMILY SSF56281 3 252 3.54E-69 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS08225 23b567a4c829c3910a26a19ed3cad51b 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.1E-8 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS08225 23b567a4c829c3910a26a19ed3cad51b 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.1E-8 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS08225 23b567a4c829c3910a26a19ed3cad51b 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.1E-8 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS08225 23b567a4c829c3910a26a19ed3cad51b 238 SUPERFAMILY SSF51735 4 237 4.03E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS08225 23b567a4c829c3910a26a19ed3cad51b 238 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 K08M4_RS08225 23b567a4c829c3910a26a19ed3cad51b 238 Gene3D G3DSA:3.40.50.720 3 237 3.8E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS08225 23b567a4c829c3910a26a19ed3cad51b 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 236 4.8E-24 T 05-07-2017 K08M4_RS10575 00437f6d2da2276f3198475c030a295d 237 Gene3D G3DSA:1.10.1060.10 106 235 3.2E-46 T 05-07-2017 K08M4_RS10575 00437f6d2da2276f3198475c030a295d 237 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 148 159 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS10575 00437f6d2da2276f3198475c030a295d 237 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 8 229 4.0E-86 T 05-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS10575 00437f6d2da2276f3198475c030a295d 237 SUPERFAMILY SSF46548 106 234 6.1E-40 T 05-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 K08M4_RS10575 00437f6d2da2276f3198475c030a295d 237 Pfam PF13534 4Fe-4S dicluster domain 147 220 2.7E-10 T 05-07-2017 K08M4_RS10575 00437f6d2da2276f3198475c030a295d 237 Gene3D G3DSA:3.10.20.30 1 105 3.7E-36 T 05-07-2017 IPR012675 Beta-grasp domain K08M4_RS10575 00437f6d2da2276f3198475c030a295d 237 SUPERFAMILY SSF54292 1 105 3.34E-30 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 K08M4_RS10575 00437f6d2da2276f3198475c030a295d 237 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 5 110 4.8E-30 T 05-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS13845 3229f11b6e4a1fb821c2b63f54d8f6bc 300 SUPERFAMILY SSF53335 29 166 1.11E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS13845 3229f11b6e4a1fb821c2b63f54d8f6bc 300 Pfam PF08241 Methyltransferase domain 34 130 1.1E-21 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 K08M4_RS13845 3229f11b6e4a1fb821c2b63f54d8f6bc 300 Gene3D G3DSA:3.40.50.150 31 185 3.8E-37 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS04815 4d5d12143b1df30eed531f2cd238baf1 194 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 158 165 - T 05-07-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS04815 4d5d12143b1df30eed531f2cd238baf1 194 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 82 3.7E-34 T 05-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS04815 4d5d12143b1df30eed531f2cd238baf1 194 SUPERFAMILY SSF46609 1 83 9.82E-35 T 05-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS04815 4d5d12143b1df30eed531f2cd238baf1 194 PIRSF PIRSF000349 1 194 7.7E-84 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS04815 4d5d12143b1df30eed531f2cd238baf1 194 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 4.0E-21 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS04815 4d5d12143b1df30eed531f2cd238baf1 194 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 4.0E-21 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS04815 4d5d12143b1df30eed531f2cd238baf1 194 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 4.0E-21 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS04815 4d5d12143b1df30eed531f2cd238baf1 194 PRINTS PR01703 Manganese superoxide dismutase signature 156 168 4.0E-21 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS04815 4d5d12143b1df30eed531f2cd238baf1 194 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 4.0E-21 T 05-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS04815 4d5d12143b1df30eed531f2cd238baf1 194 SUPERFAMILY SSF54719 85 193 5.24E-43 T 05-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS04815 4d5d12143b1df30eed531f2cd238baf1 194 Gene3D G3DSA:1.10.287.990 20 82 1.9E-23 T 05-07-2017 K08M4_RS04815 4d5d12143b1df30eed531f2cd238baf1 194 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 191 5.6E-39 T 05-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 K08M4_RS13075 6fd11bb6a2d5536c8cf0315e97ad835e 481 PIRSF PIRSF004919 15 481 1.1E-142 T 05-07-2017 IPR025502 TldD K08M4_RS13075 6fd11bb6a2d5536c8cf0315e97ad835e 481 SUPERFAMILY SSF111283 18 480 1.31E-129 T 05-07-2017 K08M4_RS13075 6fd11bb6a2d5536c8cf0315e97ad835e 481 Pfam PF01523 Putative modulator of DNA gyrase 35 332 1.1E-60 T 05-07-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 K08M4_RS13265 f9622dac6a1e6224c5ede8871ac3350f 159 Pfam PF13358 DDE superfamily endonuclease 19 127 5.0E-20 T 05-07-2017 K08M4_RS02440 6652e0d52104f11d30e0fe58fa25f960 156 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 16 149 2.6E-31 T 05-07-2017 IPR007359 Positive regulator of sigma(E), RseC/MucC K08M4_RS02440 6652e0d52104f11d30e0fe58fa25f960 156 Gene3D G3DSA:1.10.760.10 7 65 1.4E-5 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS02440 6652e0d52104f11d30e0fe58fa25f960 156 PIRSF PIRSF004923 1 156 3.3E-38 T 05-07-2017 IPR026268 Protein RseC K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 Pfam PF13481 AAA domain 71 224 5.2E-15 T 05-07-2017 K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 SUPERFAMILY SSF54211 305 456 2.05E-42 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 SUPERFAMILY SSF54211 257 271 2.05E-42 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 SMART SM00382 93 246 2.9E-9 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 SUPERFAMILY SSF52540 70 294 9.69E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 Pfam PF13541 Subunit ChlI of Mg-chelatase 347 432 2.6E-9 T 05-07-2017 K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 453 1.8E-224 T 05-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 Gene3D G3DSA:3.30.230.10 286 455 8.7E-39 T 05-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 Gene3D G3DSA:3.40.50.300 61 279 2.8E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 Hamap MF_01498 DNA repair protein RadA [radA]. 21 457 42.926 T 05-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 PRINTS PR01874 DNA repair protein radA signature 324 347 7.7E-94 T 05-07-2017 K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 PRINTS PR01874 DNA repair protein radA signature 85 113 7.7E-94 T 05-07-2017 K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 PRINTS PR01874 DNA repair protein radA signature 215 243 7.7E-94 T 05-07-2017 K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 PRINTS PR01874 DNA repair protein radA signature 10 34 7.7E-94 T 05-07-2017 K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 PRINTS PR01874 DNA repair protein radA signature 126 143 7.7E-94 T 05-07-2017 K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 PRINTS PR01874 DNA repair protein radA signature 176 200 7.7E-94 T 05-07-2017 K08M4_RS03265 035724c651f6d3a438d40c2f70378695 459 PRINTS PR01874 DNA repair protein radA signature 250 276 7.7E-94 T 05-07-2017 K08M4_RS01575 42edd3cd31962c29977032b44b734d48 118 Pfam PF00416 Ribosomal protein S13/S18 3 108 4.2E-32 T 05-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01575 42edd3cd31962c29977032b44b734d48 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 05-07-2017 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01575 42edd3cd31962c29977032b44b734d48 118 PIRSF PIRSF002134 1 118 3.5E-41 T 05-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01575 42edd3cd31962c29977032b44b734d48 118 SUPERFAMILY SSF46946 2 114 8.83E-45 T 05-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 K08M4_RS01575 42edd3cd31962c29977032b44b734d48 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 2.8E-53 T 05-07-2017 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01575 42edd3cd31962c29977032b44b734d48 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 25.778 T 05-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01575 42edd3cd31962c29977032b44b734d48 118 Gene3D G3DSA:1.10.8.50 1 71 2.6E-28 T 05-07-2017 K08M4_RS01575 42edd3cd31962c29977032b44b734d48 118 Gene3D G3DSA:4.10.910.10 72 118 3.5E-27 T 05-07-2017 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS14500 5bc6fa5b352e2e1f15f5c0155d353220 732 SUPERFAMILY SSF56349 453 627 1.47E-5 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS21785 4c7aabcb7b20810d2768ee056a064d9b 69 Gene3D G3DSA:1.20.58.250 1 63 6.8E-4 T 05-07-2017 IPR011326 Homologue of theta DNA polymerase III K08M4_RS21785 4c7aabcb7b20810d2768ee056a064d9b 69 Pfam PF11686 Protein of unknown function (DUF3283) 4 64 6.9E-35 T 05-07-2017 IPR021700 Protein of unknown function DUF3283 K08M4_RS17560 1dfa86df33d775a57a7ae283c7daf6f2 143 SUPERFAMILY SSF55729 5 138 1.36E-19 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS17560 1dfa86df33d775a57a7ae283c7daf6f2 143 Pfam PF13673 Acetyltransferase (GNAT) domain 51 135 5.3E-9 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS17560 1dfa86df33d775a57a7ae283c7daf6f2 143 Gene3D G3DSA:3.40.630.30 3 136 9.6E-19 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS05070 8af3becb02f6a4d5156d7a2d9e24877e 149 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 120 135 2.2E-22 T 05-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 K08M4_RS05070 8af3becb02f6a4d5156d7a2d9e24877e 149 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 45 61 2.2E-22 T 05-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 K08M4_RS05070 8af3becb02f6a4d5156d7a2d9e24877e 149 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 79 94 2.2E-22 T 05-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 K08M4_RS05070 8af3becb02f6a4d5156d7a2d9e24877e 149 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 2.2E-22 T 05-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 K08M4_RS05070 8af3becb02f6a4d5156d7a2d9e24877e 149 SUPERFAMILY SSF52788 1 149 1.18E-43 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily K08M4_RS05070 8af3becb02f6a4d5156d7a2d9e24877e 149 Gene3D G3DSA:3.40.50.270 1 148 1.2E-45 T 05-07-2017 K08M4_RS05070 8af3becb02f6a4d5156d7a2d9e24877e 149 SMART SM00226 2 148 6.1E-35 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily K08M4_RS05070 8af3becb02f6a4d5156d7a2d9e24877e 149 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 145 1.2E-33 T 05-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily K08M4_RS02955 64e230bc499f4c1ebaa97797a7e481f4 470 SUPERFAMILY SSF53738 250 379 1.26E-29 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS02955 64e230bc499f4c1ebaa97797a7e481f4 470 Gene3D G3DSA:3.40.120.10 2 179 7.7E-48 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS02955 64e230bc499f4c1ebaa97797a7e481f4 470 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 137 5.1E-38 T 05-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS02955 64e230bc499f4c1ebaa97797a7e481f4 470 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 417 466 2.0E-9 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS02955 64e230bc499f4c1ebaa97797a7e481f4 470 SUPERFAMILY SSF53738 2 187 8.63E-42 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS02955 64e230bc499f4c1ebaa97797a7e481f4 470 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 267 378 3.1E-25 T 05-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS02955 64e230bc499f4c1ebaa97797a7e481f4 470 SUPERFAMILY SSF55957 374 465 4.06E-18 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS02955 64e230bc499f4c1ebaa97797a7e481f4 470 Gene3D G3DSA:3.30.310.50 395 468 1.2E-19 T 05-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS02955 64e230bc499f4c1ebaa97797a7e481f4 470 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 162 262 1.1E-23 T 05-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS02955 64e230bc499f4c1ebaa97797a7e481f4 470 Gene3D G3DSA:3.40.120.10 181 255 8.0E-24 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS02955 64e230bc499f4c1ebaa97797a7e481f4 470 Gene3D G3DSA:3.40.120.10 256 382 1.2E-34 T 05-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS02955 64e230bc499f4c1ebaa97797a7e481f4 470 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 1.1E-11 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS02955 64e230bc499f4c1ebaa97797a7e481f4 470 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 242 257 1.1E-11 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS02955 64e230bc499f4c1ebaa97797a7e481f4 470 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 180 199 1.1E-11 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS02955 64e230bc499f4c1ebaa97797a7e481f4 470 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 214 227 1.1E-11 T 05-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 K08M4_RS21385 4c39e00fefc1355b0650c401e2a4f7c3 290 SUPERFAMILY SSF51182 6 288 1.35E-72 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS21385 4c39e00fefc1355b0650c401e2a4f7c3 290 Gene3D G3DSA:2.60.120.10 2 261 3.0E-75 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS21385 4c39e00fefc1355b0650c401e2a4f7c3 290 Pfam PF02678 Pirin 31 121 2.5E-33 T 05-07-2017 IPR003829 Pirin, N-terminal domain K08M4_RS21385 4c39e00fefc1355b0650c401e2a4f7c3 290 Pfam PF05726 Pirin C-terminal cupin domain 189 287 8.9E-27 T 05-07-2017 IPR008778 Pirin, C-terminal domain K08M4_RS21385 4c39e00fefc1355b0650c401e2a4f7c3 290 PIRSF PIRSF006232 3 290 2.0E-80 T 05-07-2017 IPR012093 Pirin K08M4_RS06855 df337ace71578b687fd4cef68ede32d0 898 SUPERFAMILY SSF52540 292 343 1.01E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06855 df337ace71578b687fd4cef68ede32d0 898 SUPERFAMILY SSF52540 675 758 1.01E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06855 df337ace71578b687fd4cef68ede32d0 898 SMART SM00382 292 764 0.0097 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS06855 df337ace71578b687fd4cef68ede32d0 898 Gene3D G3DSA:3.40.50.300 294 390 4.3E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06855 df337ace71578b687fd4cef68ede32d0 898 Gene3D G3DSA:3.40.50.300 678 756 4.3E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06855 df337ace71578b687fd4cef68ede32d0 898 Pfam PF07728 AAA domain (dynein-related subfamily) 676 754 9.2E-10 T 05-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 K08M4_RS03425 2336dc872e2043b56d0958b0ff0ead77 308 Gene3D G3DSA:1.10.10.10 5 86 1.1E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS03425 2336dc872e2043b56d0958b0ff0ead77 308 Gene3D G3DSA:3.40.190.10 176 273 2.6E-20 T 05-07-2017 K08M4_RS03425 2336dc872e2043b56d0958b0ff0ead77 308 SUPERFAMILY SSF53850 93 299 4.34E-30 T 05-07-2017 K08M4_RS03425 2336dc872e2043b56d0958b0ff0ead77 308 Pfam PF03466 LysR substrate binding domain 99 301 5.6E-21 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS03425 2336dc872e2043b56d0958b0ff0ead77 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 3.4E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS03425 2336dc872e2043b56d0958b0ff0ead77 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 3.4E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS03425 2336dc872e2043b56d0958b0ff0ead77 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 3.4E-5 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS03425 2336dc872e2043b56d0958b0ff0ead77 308 SUPERFAMILY SSF46785 7 85 7.32E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS03425 2336dc872e2043b56d0958b0ff0ead77 308 Gene3D G3DSA:3.40.190.10 277 304 1.9E-18 T 05-07-2017 K08M4_RS03425 2336dc872e2043b56d0958b0ff0ead77 308 Gene3D G3DSA:3.40.190.10 93 175 1.9E-18 T 05-07-2017 K08M4_RS03425 2336dc872e2043b56d0958b0ff0ead77 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 68 2.7E-15 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS05160 9fb7068db13363d0f69c048f85cb203e 476 Pfam PF02378 Phosphotransferase system, EIIC 13 318 4.4E-73 T 05-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 K08M4_RS05160 9fb7068db13363d0f69c048f85cb203e 476 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 376 458 2.0E-19 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS05160 9fb7068db13363d0f69c048f85cb203e 476 SUPERFAMILY SSF55604 399 471 1.22E-19 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS05160 9fb7068db13363d0f69c048f85cb203e 476 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 412 429 - T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS05160 9fb7068db13363d0f69c048f85cb203e 476 Pfam PF00367 phosphotransferase system, EIIB 402 434 3.9E-11 T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS05160 9fb7068db13363d0f69c048f85cb203e 476 Gene3D G3DSA:3.30.1360.60 397 472 1.8E-25 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS05160 9fb7068db13363d0f69c048f85cb203e 476 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 473 5.6E-194 T 05-07-2017 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0015758|GO:0016021 K08M4_RS13705 84ddb042bf09ee06ed2ebaca2cf45655 477 Gene3D G3DSA:3.30.70.270 314 474 6.2E-41 T 05-07-2017 K08M4_RS13705 84ddb042bf09ee06ed2ebaca2cf45655 477 Pfam PF00990 Diguanylate cyclase, GGDEF domain 312 471 8.1E-32 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS13705 84ddb042bf09ee06ed2ebaca2cf45655 477 Gene3D G3DSA:3.30.450.20 115 214 4.9E-7 T 05-07-2017 K08M4_RS13705 84ddb042bf09ee06ed2ebaca2cf45655 477 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 308 473 5.0E-38 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS13705 84ddb042bf09ee06ed2ebaca2cf45655 477 SMART SM00267 301 475 3.0E-41 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS13705 84ddb042bf09ee06ed2ebaca2cf45655 477 SUPERFAMILY SSF55073 317 474 9.42E-34 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS08305 7e2bdd787f401530f7b8514c7b910ae8 261 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 80 2.8E-10 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS08305 7e2bdd787f401530f7b8514c7b910ae8 261 SUPERFAMILY SSF46689 23 85 8.21E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS08305 7e2bdd787f401530f7b8514c7b910ae8 261 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 2.1E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS08305 7e2bdd787f401530f7b8514c7b910ae8 261 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 2.1E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS08305 7e2bdd787f401530f7b8514c7b910ae8 261 Gene3D G3DSA:1.10.357.10 23 202 1.5E-20 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS03500 e0b7de74c56424a63fdc001bd6190c70 218 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 198 2.9E-66 T 05-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS03500 e0b7de74c56424a63fdc001bd6190c70 218 PIRSF PIRSF000498 1 212 2.4E-80 T 05-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS03500 e0b7de74c56424a63fdc001bd6190c70 218 SUPERFAMILY SSF63380 93 197 1.62E-32 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 K08M4_RS03500 e0b7de74c56424a63fdc001bd6190c70 218 SUPERFAMILY SSF63380 1 89 8.33E-25 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 K08M4_RS03500 e0b7de74c56424a63fdc001bd6190c70 218 Pfam PF00677 Lumazine binding domain 100 184 7.7E-21 T 05-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS03500 e0b7de74c56424a63fdc001bd6190c70 218 Pfam PF00677 Lumazine binding domain 3 87 4.9E-20 T 05-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS03500 e0b7de74c56424a63fdc001bd6190c70 218 Gene3D G3DSA:2.40.30.20 105 196 3.6E-32 T 05-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 K08M4_RS03500 e0b7de74c56424a63fdc001bd6190c70 218 Gene3D G3DSA:2.40.30.20 5 104 1.2E-30 T 05-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 K08M4_RS10745 125630b3c0145ffe026e75a30a162598 275 SUPERFAMILY SSF51735 2 265 3.75E-55 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS10745 125630b3c0145ffe026e75a30a162598 275 Pfam PF00106 short chain dehydrogenase 3 187 2.2E-38 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS10745 125630b3c0145ffe026e75a30a162598 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 K08M4_RS10745 125630b3c0145ffe026e75a30a162598 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.5E-15 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS10745 125630b3c0145ffe026e75a30a162598 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 1.5E-15 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS10745 125630b3c0145ffe026e75a30a162598 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 1.5E-15 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS10745 125630b3c0145ffe026e75a30a162598 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.5E-15 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS10745 125630b3c0145ffe026e75a30a162598 275 Gene3D G3DSA:3.40.50.720 2 273 1.5E-59 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS21775 ca4bfebe9c219afe7ae009ea279ab280 291 Gene3D G3DSA:3.40.50.720 1 166 2.0E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS21775 ca4bfebe9c219afe7ae009ea279ab280 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 160 4.7E-48 T 05-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 K08M4_RS21775 ca4bfebe9c219afe7ae009ea279ab280 291 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 283 9.7E-31 T 05-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 K08M4_RS21775 ca4bfebe9c219afe7ae009ea279ab280 291 PIRSF PIRSF000103 1 291 3.7E-72 T 05-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 K08M4_RS21775 ca4bfebe9c219afe7ae009ea279ab280 291 SUPERFAMILY SSF48179 164 286 1.47E-36 T 05-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 K08M4_RS21775 ca4bfebe9c219afe7ae009ea279ab280 291 Gene3D G3DSA:1.10.1040.10 167 288 4.8E-39 T 05-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 K08M4_RS21775 ca4bfebe9c219afe7ae009ea279ab280 291 SUPERFAMILY SSF51735 1 163 7.73E-51 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS21775 ca4bfebe9c219afe7ae009ea279ab280 291 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 05-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 K08M4_RS05800 1a72424a5b1a88681872f2da047f33da 205 Pfam PF01066 CDP-alcohol phosphatidyltransferase 26 89 8.4E-9 T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 K08M4_RS05800 1a72424a5b1a88681872f2da047f33da 205 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 89 - T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 K08M4_RS06150 045376a32a5d03bb25ca3df1e2fec83a 192 SUPERFAMILY SSF48498 79 179 7.21E-7 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal K08M4_RS06150 045376a32a5d03bb25ca3df1e2fec83a 192 Gene3D G3DSA:1.10.357.10 4 181 1.2E-31 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS06150 045376a32a5d03bb25ca3df1e2fec83a 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 5.0E-11 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS06150 045376a32a5d03bb25ca3df1e2fec83a 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 5.0E-11 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS06150 045376a32a5d03bb25ca3df1e2fec83a 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site K08M4_RS06150 045376a32a5d03bb25ca3df1e2fec83a 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 3.8E-16 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS06150 045376a32a5d03bb25ca3df1e2fec83a 192 SUPERFAMILY SSF46689 4 69 2.89E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS12805 cba460690601defe334ae2513471b5c9 198 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 2 195 2.5E-74 T 05-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 K08M4_RS12805 cba460690601defe334ae2513471b5c9 198 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 7 193 19.525 T 05-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 K08M4_RS12805 cba460690601defe334ae2513471b5c9 198 SMART SM01207 10 185 9.9E-88 T 05-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 K08M4_RS12805 cba460690601defe334ae2513471b5c9 198 Pfam PF02660 Glycerol-3-phosphate acyltransferase 12 184 1.6E-51 T 05-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 K08M4_RS19805 712e5202bd42b2eba88887578e153ee4 242 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 219 235 6.6E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS19805 712e5202bd42b2eba88887578e153ee4 242 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 204 219 6.6E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS19805 712e5202bd42b2eba88887578e153ee4 242 SUPERFAMILY SSF51182 14 161 2.76E-10 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS19805 712e5202bd42b2eba88887578e153ee4 242 Pfam PF12833 Helix-turn-helix domain 158 235 5.2E-23 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS19805 712e5202bd42b2eba88887578e153ee4 242 SUPERFAMILY SSF46689 188 236 1.03E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS19805 712e5202bd42b2eba88887578e153ee4 242 Gene3D G3DSA:1.10.10.60 134 188 1.1E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS19805 712e5202bd42b2eba88887578e153ee4 242 SMART SM00342 152 235 1.8E-31 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS19805 712e5202bd42b2eba88887578e153ee4 242 Gene3D G3DSA:2.60.120.10 14 70 3.5E-7 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS19805 712e5202bd42b2eba88887578e153ee4 242 Gene3D G3DSA:1.10.10.60 189 234 7.0E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS20900 aebf5546ef2e43eff1f5cfce02772aab 686 Gene3D G3DSA:2.60.40.1180 466 537 2.7E-5 T 05-07-2017 IPR013780 Glycosyl hydrolase, all-beta K08M4_RS20900 aebf5546ef2e43eff1f5cfce02772aab 686 SMART SM00642 64 449 4.7E-28 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS20900 aebf5546ef2e43eff1f5cfce02772aab 686 Gene3D G3DSA:3.20.20.80 51 458 1.1E-65 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS20900 aebf5546ef2e43eff1f5cfce02772aab 686 SUPERFAMILY SSF51445 50 459 7.05E-71 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS20900 aebf5546ef2e43eff1f5cfce02772aab 686 Pfam PF00128 Alpha amylase, catalytic domain 207 392 4.9E-16 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS20900 aebf5546ef2e43eff1f5cfce02772aab 686 Pfam PF00128 Alpha amylase, catalytic domain 90 177 4.9E-26 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS20900 aebf5546ef2e43eff1f5cfce02772aab 686 SUPERFAMILY SSF51011 458 536 4.32E-7 T 05-07-2017 K08M4_RS19035 c5d60ecb3f631f783f479587ec612dbb 363 Pfam PF14319 Transposase zinc-binding domain 17 114 7.4E-32 T 05-07-2017 IPR026889 Transposase zinc-binding domain K08M4_RS19035 c5d60ecb3f631f783f479587ec612dbb 363 Pfam PF04986 Putative transposase 140 306 7.9E-44 T 05-07-2017 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 K08M4_RS08865 c5d60ecb3f631f783f479587ec612dbb 363 Pfam PF14319 Transposase zinc-binding domain 17 114 7.4E-32 T 05-07-2017 IPR026889 Transposase zinc-binding domain K08M4_RS08865 c5d60ecb3f631f783f479587ec612dbb 363 Pfam PF04986 Putative transposase 140 306 7.9E-44 T 05-07-2017 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 K08M4_RS20110 7135d69d1409c77916242e9e4ca403ce 343 SUPERFAMILY SSF56349 122 334 3.24E-36 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS20110 7135d69d1409c77916242e9e4ca403ce 343 Pfam PF00589 Phage integrase family 285 326 4.5E-11 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS20110 7135d69d1409c77916242e9e4ca403ce 343 Pfam PF00589 Phage integrase family 180 252 1.1E-6 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS20110 7135d69d1409c77916242e9e4ca403ce 343 Gene3D G3DSA:1.10.443.10 176 335 3.7E-35 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS10345 30dfb0726f0378846656de396fb9b346 194 Hamap MF_01100 5'-deoxynucleotidase YfbR [yfbR]. 3 194 45.138 T 05-07-2017 IPR022971 5'-deoxynucleotidase YfbR KEGG: 00240+3.1.3.89 K08M4_RS10345 30dfb0726f0378846656de396fb9b346 194 ProDom PD353566 UPF0207 HYDROLASE HD PHOSPHOHYDROLASE METAL-DEPENDENT SUBDOMAIN YFBR PHOSPHOHYDROLASE NUCLEOTIDE-BINDING NUCLEOSIDE 80 184 4.0E-41 T 05-07-2017 K08M4_RS10345 30dfb0726f0378846656de396fb9b346 194 SMART SM00471 26 151 3.6E-6 T 05-07-2017 IPR003607 HD/PDEase domain K08M4_RS10345 30dfb0726f0378846656de396fb9b346 194 SUPERFAMILY SSF109604 3 184 1.26E-43 T 05-07-2017 K08M4_RS10345 30dfb0726f0378846656de396fb9b346 194 Pfam PF13023 HD domain 11 160 1.6E-14 T 05-07-2017 IPR006674 HD domain K08M4_RS10345 30dfb0726f0378846656de396fb9b346 194 Gene3D G3DSA:1.10.3210.10 2 193 2.9E-47 T 05-07-2017 IPR006674 HD domain K08M4_RS04250 6effc4e241429800bc5909bcb6f7a2d0 243 Pfam PF04344 Chemotaxis phosphatase, CheZ 41 243 3.2E-75 T 05-07-2017 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 K08M4_RS04250 6effc4e241429800bc5909bcb6f7a2d0 243 SUPERFAMILY SSF75708 30 242 2.09E-65 T 05-07-2017 K08M4_RS04250 6effc4e241429800bc5909bcb6f7a2d0 243 Gene3D G3DSA:1.10.287.500 62 193 2.8E-49 T 05-07-2017 K08M4_RS04250 6effc4e241429800bc5909bcb6f7a2d0 243 PIRSF PIRSF002884 13 243 1.9E-86 T 05-07-2017 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 K08M4_RS03665 12c93d6dba0d9039c6ced5f5b60e2c6b 373 SUPERFAMILY SSF52540 101 320 4.62E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03665 12c93d6dba0d9039c6ced5f5b60e2c6b 373 Pfam PF02562 PhoH-like protein 120 323 1.4E-94 T 05-07-2017 IPR003714 PhoH-like protein GO:0005524 K08M4_RS03665 12c93d6dba0d9039c6ced5f5b60e2c6b 373 Gene3D G3DSA:3.40.50.300 120 323 3.1E-88 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06550 61cc69b804df5254d647bdd120c0bf19 342 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 3 340 4.7E-129 T 05-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 K08M4_RS06550 61cc69b804df5254d647bdd120c0bf19 342 SUPERFAMILY SSF52733 2 341 3.66E-114 T 05-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 K08M4_RS06550 61cc69b804df5254d647bdd120c0bf19 342 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 1 342 36.093 T 05-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 K08M4_RS06550 61cc69b804df5254d647bdd120c0bf19 342 Gene3D G3DSA:1.10.1610.10 2 66 2.3E-27 T 05-07-2017 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 K08M4_RS06550 61cc69b804df5254d647bdd120c0bf19 342 Pfam PF02277 Phosphoribosyltransferase 2 340 1.7E-128 T 05-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 K08M4_RS06550 61cc69b804df5254d647bdd120c0bf19 342 Gene3D G3DSA:3.40.50.10210 67 323 1.6E-105 T 05-07-2017 K08M4_RS03185 ed0b4359758d87a306e7f1fa1454171e 167 Gene3D G3DSA:3.40.630.30 1 127 1.7E-18 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS03185 ed0b4359758d87a306e7f1fa1454171e 167 Pfam PF13527 Acetyltransferase (GNAT) domain 3 123 9.8E-9 T 05-07-2017 K08M4_RS03185 ed0b4359758d87a306e7f1fa1454171e 167 SUPERFAMILY SSF55729 1 128 2.44E-25 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS21595 393ea5a0c83a15b2ec0aeb2aa23200c0 173 Pfam PF11086 Protein of unknown function (DUF2878) 5 156 6.9E-37 T 05-07-2017 IPR021306 Protein of unknown function DUF2878 K08M4_RS15175 6c18fad33165d81d24879146159b687f 98 Pfam PF06291 Bor protein 1 97 3.6E-36 T 05-07-2017 IPR010438 Bor GO:0009279 K08M4_RS15175 6c18fad33165d81d24879146159b687f 98 ProDom PD020173 BOR LIPOPROTEIN PLASMID ISS HOMOLOG MEMBRANE FROM PRECURSOR PALMITATE DLP12 1 96 1.0E-27 T 05-07-2017 IPR010438 Bor GO:0009279 K08M4_RS06280 740e5796f06efe0243dbf434f85e2652 98 SMART SM00886 2 98 2.1E-32 T 05-07-2017 IPR013097 Stress responsive alpha-beta barrel K08M4_RS06280 740e5796f06efe0243dbf434f85e2652 98 Pfam PF07876 Stress responsive A/B Barrel Domain 2 97 2.7E-30 T 05-07-2017 IPR013097 Stress responsive alpha-beta barrel K08M4_RS06280 740e5796f06efe0243dbf434f85e2652 98 Gene3D G3DSA:3.30.70.900 1 96 9.9E-38 T 05-07-2017 K08M4_RS06280 740e5796f06efe0243dbf434f85e2652 98 SUPERFAMILY SSF54909 2 97 4.4E-30 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel K08M4_RS17480 bc70143524b19ba6523d41647c416fcd 166 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 77 165 1.2E-21 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS18525 0b4c58bcf9b0c9c54524929449f7b6ea 384 Gene3D G3DSA:2.40.160.60 202 305 8.4E-6 T 05-07-2017 K08M4_RS18525 0b4c58bcf9b0c9c54524929449f7b6ea 384 Gene3D G3DSA:2.40.160.60 24 86 8.4E-6 T 05-07-2017 K08M4_RS18525 0b4c58bcf9b0c9c54524929449f7b6ea 384 Pfam PF13729 F plasmid transfer operon, TraF, protein 47 300 3.7E-74 T 05-07-2017 IPR032811 Putative conjugal transfer protein TraF-related K08M4_RS11875 cad11a9ec577cdfbc675bd50139ce0cd 112 PRINTS PR00355 Adrenodoxin signature 42 52 2.0E-10 T 05-07-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 K08M4_RS11875 cad11a9ec577cdfbc675bd50139ce0cd 112 PRINTS PR00355 Adrenodoxin signature 83 91 2.0E-10 T 05-07-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 K08M4_RS11875 cad11a9ec577cdfbc675bd50139ce0cd 112 PRINTS PR00355 Adrenodoxin signature 60 74 2.0E-10 T 05-07-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 K08M4_RS11875 cad11a9ec577cdfbc675bd50139ce0cd 112 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 05-07-2017 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 K08M4_RS11875 cad11a9ec577cdfbc675bd50139ce0cd 112 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 111 2.8E-59 T 05-07-2017 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 K08M4_RS11875 cad11a9ec577cdfbc675bd50139ce0cd 112 SUPERFAMILY SSF54292 5 105 1.15E-30 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 K08M4_RS11875 cad11a9ec577cdfbc675bd50139ce0cd 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 91 2.7E-14 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 K08M4_RS11875 cad11a9ec577cdfbc675bd50139ce0cd 112 Gene3D G3DSA:3.10.20.30 4 108 4.2E-33 T 05-07-2017 IPR012675 Beta-grasp domain K08M4_RS04225 8ed293b0ec50fab1dd8abf985f68e693 700 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 75 94 3.6E-56 T 05-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 K08M4_RS04225 8ed293b0ec50fab1dd8abf985f68e693 700 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 161 179 3.6E-56 T 05-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 K08M4_RS04225 8ed293b0ec50fab1dd8abf985f68e693 700 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 191 208 3.6E-56 T 05-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 K08M4_RS04225 8ed293b0ec50fab1dd8abf985f68e693 700 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 38 51 3.6E-56 T 05-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 K08M4_RS04225 8ed293b0ec50fab1dd8abf985f68e693 700 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 142 158 3.6E-56 T 05-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 K08M4_RS04225 8ed293b0ec50fab1dd8abf985f68e693 700 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 242 256 3.6E-56 T 05-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 K08M4_RS04225 8ed293b0ec50fab1dd8abf985f68e693 700 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 22 697 1.5E-264 T 05-07-2017 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 K08M4_RS04225 8ed293b0ec50fab1dd8abf985f68e693 700 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 147 170 - T 05-07-2017 IPR025505 FHIPEP conserved site K08M4_RS04225 8ed293b0ec50fab1dd8abf985f68e693 700 Pfam PF00771 FHIPEP family 32 690 1.6E-268 T 05-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 K08M4_RS04225 8ed293b0ec50fab1dd8abf985f68e693 700 PIRSF PIRSF005419 11 700 6.5E-251 T 05-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 K08M4_RS14395 ae94b2ad8e4f8563c8a135e53a89fc4e 135 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 4.2E-27 T 05-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 K08M4_RS14395 ae94b2ad8e4f8563c8a135e53a89fc4e 135 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 4.2E-27 T 05-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 K08M4_RS14395 ae94b2ad8e4f8563c8a135e53a89fc4e 135 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 4.2E-27 T 05-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 K08M4_RS14395 ae94b2ad8e4f8563c8a135e53a89fc4e 135 Pfam PF02416 mttA/Hcf106 family 4 32 1.2E-4 T 05-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 K08M4_RS14395 ae94b2ad8e4f8563c8a135e53a89fc4e 135 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 133 17.87 T 05-07-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 K08M4_RS14395 ae94b2ad8e4f8563c8a135e53a89fc4e 135 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 80 6.5E-32 T 05-07-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 K08M4_RS07595 2d09c1fbb360cd63d1f8ee60e75ee552 371 Pfam PF00005 ABC transporter 29 168 8.7E-35 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS07595 2d09c1fbb360cd63d1f8ee60e75ee552 371 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 42 365 4.2E-156 T 05-07-2017 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 K08M4_RS07595 2d09c1fbb360cd63d1f8ee60e75ee552 371 Gene3D G3DSA:3.40.50.300 10 242 7.1E-82 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07595 2d09c1fbb360cd63d1f8ee60e75ee552 371 Pfam PF08402 TOBE domain 286 365 7.6E-12 T 05-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 K08M4_RS07595 2d09c1fbb360cd63d1f8ee60e75ee552 371 SMART SM00382 36 219 5.8E-20 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS07595 2d09c1fbb360cd63d1f8ee60e75ee552 371 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS07595 2d09c1fbb360cd63d1f8ee60e75ee552 371 SUPERFAMILY SSF52540 12 249 8.25E-88 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07595 2d09c1fbb360cd63d1f8ee60e75ee552 371 SUPERFAMILY SSF50331 244 365 1.98E-8 T 05-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal K08M4_RS01400 3582ca5e08a91c363f646726363f924c 321 Pfam PF01112 Asparaginase 7 318 5.3E-109 T 05-07-2017 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 K08M4_RS01400 3582ca5e08a91c363f646726363f924c 321 SUPERFAMILY SSF56235 5 156 1.1E-95 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS01400 3582ca5e08a91c363f646726363f924c 321 SUPERFAMILY SSF56235 183 317 1.1E-95 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS02980 60b9eb4a37c7a03e10c98c735f2a401b 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 328 4.9E-24 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS02980 60b9eb4a37c7a03e10c98c735f2a401b 331 Gene3D G3DSA:3.40.50.300 10 265 9.9E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02980 60b9eb4a37c7a03e10c98c735f2a401b 331 Pfam PF00005 ABC transporter 35 192 2.2E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS02980 60b9eb4a37c7a03e10c98c735f2a401b 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 308 1.4E-18 T 05-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 K08M4_RS02980 60b9eb4a37c7a03e10c98c735f2a401b 331 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS02980 60b9eb4a37c7a03e10c98c735f2a401b 331 SMART SM00382 43 241 8.2E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS02980 60b9eb4a37c7a03e10c98c735f2a401b 331 SUPERFAMILY SSF52540 10 262 3.68E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02935 a6b94aaca402e7e23b6a19ae9f34f865 409 ProSitePatterns PS01219 Ammonium transporters signature. 163 188 - T 05-07-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 K08M4_RS02935 a6b94aaca402e7e23b6a19ae9f34f865 409 TIGRFAM TIGR03644 marine_trans_1: probable ammonium transporter, marine subtype 12 405 3.3E-204 T 05-07-2017 IPR019879 Ammonium transporter, marine subtype K08M4_RS02935 a6b94aaca402e7e23b6a19ae9f34f865 409 Gene3D G3DSA:1.10.3430.10 27 398 1.1E-106 T 05-07-2017 IPR029020 Ammonium/urea transporter K08M4_RS02935 a6b94aaca402e7e23b6a19ae9f34f865 409 Pfam PF00909 Ammonium Transporter Family 18 402 6.0E-99 T 05-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 K08M4_RS02935 a6b94aaca402e7e23b6a19ae9f34f865 409 SUPERFAMILY SSF111352 12 383 5.62E-105 T 05-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 K08M4_RS19445 07b751ca77e1c8db26758798a50807b7 501 SUPERFAMILY SSF52540 5 228 1.25E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19445 07b751ca77e1c8db26758798a50807b7 501 SMART SM00382 30 225 1.4E-7 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS19445 07b751ca77e1c8db26758798a50807b7 501 SMART SM00382 278 472 5.1E-6 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS19445 07b751ca77e1c8db26758798a50807b7 501 Gene3D G3DSA:3.40.50.300 269 482 1.5E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19445 07b751ca77e1c8db26758798a50807b7 501 Gene3D G3DSA:3.40.50.300 2 232 2.0E-63 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19445 07b751ca77e1c8db26758798a50807b7 501 Pfam PF00005 ABC transporter 270 423 1.0E-24 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS19445 07b751ca77e1c8db26758798a50807b7 501 Pfam PF00005 ABC transporter 21 170 1.5E-32 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS19445 07b751ca77e1c8db26758798a50807b7 501 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS19445 07b751ca77e1c8db26758798a50807b7 501 SUPERFAMILY SSF52540 269 481 1.55E-46 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19445 07b751ca77e1c8db26758798a50807b7 501 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS08840 a7880f43cbb0db08c991a1ea12b25b05 295 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 12 92 1.8E-18 T 05-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 K08M4_RS08840 a7880f43cbb0db08c991a1ea12b25b05 295 SUPERFAMILY SSF56349 11 279 1.06E-56 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS08840 a7880f43cbb0db08c991a1ea12b25b05 295 Gene3D G3DSA:1.10.150.130 11 91 1.0E-5 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal K08M4_RS08840 a7880f43cbb0db08c991a1ea12b25b05 295 Gene3D G3DSA:1.10.443.10 108 277 6.9E-48 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS08840 a7880f43cbb0db08c991a1ea12b25b05 295 Pfam PF00589 Phage integrase family 109 270 1.9E-40 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS05025 47e54c315d62e1c9cd8b97d16a9adea5 169 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 4 165 21.746 T 05-07-2017 IPR022920 Disulphide bond formation protein DsbB K08M4_RS05025 47e54c315d62e1c9cd8b97d16a9adea5 169 Gene3D G3DSA:1.20.1550.10 2 168 1.1E-63 T 05-07-2017 IPR023380 Disulphide bond formation protein DsbB-like domain K08M4_RS05025 47e54c315d62e1c9cd8b97d16a9adea5 169 Pfam PF02600 Disulfide bond formation protein DsbB 9 155 1.6E-43 T 05-07-2017 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 K08M4_RS05025 47e54c315d62e1c9cd8b97d16a9adea5 169 SUPERFAMILY SSF158442 12 157 2.35E-43 T 05-07-2017 K08M4_RS07170 27efa05bfe71105ccf3d89061aa1d20c 751 Pfam PF12392 Collagenase 340 437 9.7E-5 T 05-07-2017 IPR020988 Peptidase U32, collagenase K08M4_RS07170 27efa05bfe71105ccf3d89061aa1d20c 751 Pfam PF01136 Peptidase family U32 77 292 1.3E-67 T 05-07-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 K08M4_RS07170 27efa05bfe71105ccf3d89061aa1d20c 751 Pfam PF01136 Peptidase family U32 530 664 3.2E-6 T 05-07-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 K08M4_RS08945 b0d81e834bc7696411a64f07dc226788 133 Gene3D G3DSA:3.90.1010.10 4 132 1.2E-45 T 05-07-2017 K08M4_RS08945 b0d81e834bc7696411a64f07dc226788 133 SUPERFAMILY SSF82649 4 130 4.03E-38 T 05-07-2017 K08M4_RS08945 b0d81e834bc7696411a64f07dc226788 133 Pfam PF02657 Fe-S metabolism associated domain 8 126 5.0E-40 T 05-07-2017 IPR003808 Fe-S metabolism associated domain, SufE-like K08M4_RS07955 b3ebfec39531f6700382e753f7b175bc 204 Pfam PF00691 OmpA family 85 170 2.9E-17 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS07955 b3ebfec39531f6700382e753f7b175bc 204 SUPERFAMILY SSF103088 65 183 4.32E-28 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS07955 b3ebfec39531f6700382e753f7b175bc 204 PRINTS PR01021 OMPA domain signature 131 147 2.1E-9 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS07955 b3ebfec39531f6700382e753f7b175bc 204 PRINTS PR01021 OMPA domain signature 86 108 2.1E-9 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS07955 b3ebfec39531f6700382e753f7b175bc 204 PRINTS PR01021 OMPA domain signature 116 131 2.1E-9 T 05-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 K08M4_RS07955 b3ebfec39531f6700382e753f7b175bc 204 SUPERFAMILY SSF103647 39 72 3.14E-6 T 05-07-2017 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 K08M4_RS07955 b3ebfec39531f6700382e753f7b175bc 204 Gene3D G3DSA:4.10.1080.10 40 75 1.2E-4 T 05-07-2017 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 K08M4_RS07955 b3ebfec39531f6700382e753f7b175bc 204 Gene3D G3DSA:3.30.1330.60 81 186 2.1E-28 T 05-07-2017 IPR006665 OmpA-like domain K08M4_RS15335 53e5724bb4ec78d2ae39d06c3c1f96bc 209 Gene3D G3DSA:3.20.20.70 3 208 2.2E-74 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS15335 53e5724bb4ec78d2ae39d06c3c1f96bc 209 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 124 137 - T 05-07-2017 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 K08M4_RS15335 53e5724bb4ec78d2ae39d06c3c1f96bc 209 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 6 206 4.0E-83 T 05-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 K08M4_RS15335 53e5724bb4ec78d2ae39d06c3c1f96bc 209 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 36 45 - T 05-07-2017 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 K08M4_RS15335 53e5724bb4ec78d2ae39d06c3c1f96bc 209 SUPERFAMILY SSF51569 3 207 1.45E-66 T 05-07-2017 K08M4_RS15335 53e5724bb4ec78d2ae39d06c3c1f96bc 209 Pfam PF01081 KDPG and KHG aldolase 4 199 2.4E-78 T 05-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 K08M4_RS02915 7d3aa79a94fbf6d26d26766fdf4c6b5c 779 Gene3D G3DSA:3.40.1090.10 48 242 5.2E-14 T 05-07-2017 K08M4_RS02915 7d3aa79a94fbf6d26d26766fdf4c6b5c 779 Pfam PF01734 Patatin-like phospholipase 49 239 2.2E-29 T 05-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 K08M4_RS02915 7d3aa79a94fbf6d26d26766fdf4c6b5c 779 SUPERFAMILY SSF52151 43 115 3.4E-57 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 K08M4_RS02915 7d3aa79a94fbf6d26d26766fdf4c6b5c 779 SUPERFAMILY SSF52151 145 333 3.4E-57 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 K08M4_RS02915 7d3aa79a94fbf6d26d26766fdf4c6b5c 779 SUPERFAMILY SSF56935 468 705 4.03E-5 T 05-07-2017 K08M4_RS15770 d807ced89c9c657e8ff92e69b7b70c48 543 Gene3D G3DSA:3.20.20.80 176 465 6.8E-126 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS15770 d807ced89c9c657e8ff92e69b7b70c48 543 Gene3D G3DSA:3.20.20.80 2 104 6.8E-126 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS15770 d807ced89c9c657e8ff92e69b7b70c48 543 Gene3D G3DSA:3.90.400.10 105 175 1.3E-30 T 05-07-2017 K08M4_RS15770 d807ced89c9c657e8ff92e69b7b70c48 543 SMART SM00642 13 405 3.8E-149 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS15770 d807ced89c9c657e8ff92e69b7b70c48 543 SUPERFAMILY SSF51011 466 542 4.95E-19 T 05-07-2017 K08M4_RS15770 d807ced89c9c657e8ff92e69b7b70c48 543 Pfam PF16657 Maltogenic Amylase, C-terminal domain 466 539 1.1E-10 T 05-07-2017 IPR032091 Maltogenic Amylase, C-terminal K08M4_RS15770 d807ced89c9c657e8ff92e69b7b70c48 543 Gene3D G3DSA:2.60.40.1180 468 542 1.1E-22 T 05-07-2017 IPR013780 Glycosyl hydrolase, all-beta K08M4_RS15770 d807ced89c9c657e8ff92e69b7b70c48 543 Pfam PF00128 Alpha amylase, catalytic domain 28 363 3.0E-120 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS15770 d807ced89c9c657e8ff92e69b7b70c48 543 SUPERFAMILY SSF51445 3 463 2.05E-158 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS01090 95c73a1ace812df4a5eaeb3e3e73df52 115 SUPERFAMILY SSF55331 2 115 5.19E-34 T 05-07-2017 IPR014347 Tautomerase/MIF superfamily K08M4_RS01090 95c73a1ace812df4a5eaeb3e3e73df52 115 Pfam PF02962 5-carboxymethyl-2-hydroxymuconate isomerase 2 90 5.6E-7 T 05-07-2017 IPR004220 5-carboxymethyl-2-hydroxymuconate isomerase GO:0008704|GO:0019439 KEGG: 00350+5.3.3.10 K08M4_RS01090 95c73a1ace812df4a5eaeb3e3e73df52 115 Gene3D G3DSA:3.30.429.10 1 115 5.4E-38 T 05-07-2017 K08M4_RS05110 ff265b099b6ec13023926a4e247dc0bc 316 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 183 1.7E-31 T 05-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 K08M4_RS05110 ff265b099b6ec13023926a4e247dc0bc 316 Gene3D G3DSA:3.40.47.10 1 160 2.8E-68 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS05110 ff265b099b6ec13023926a4e247dc0bc 316 SUPERFAMILY SSF53901 3 315 4.4E-70 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS05110 ff265b099b6ec13023926a4e247dc0bc 316 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 316 72.725 T 05-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 K08M4_RS05110 ff265b099b6ec13023926a4e247dc0bc 316 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 227 315 8.6E-35 T 05-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 K08M4_RS05110 ff265b099b6ec13023926a4e247dc0bc 316 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 316 4.7E-143 T 05-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 K08M4_RS05110 ff265b099b6ec13023926a4e247dc0bc 316 Gene3D G3DSA:3.40.47.10 161 315 5.8E-51 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS14220 82e65436d5de57dcfbcd8179bf12ee7e 131 Gene3D G3DSA:3.30.1300.30 46 130 3.0E-27 T 05-07-2017 K08M4_RS14220 82e65436d5de57dcfbcd8179bf12ee7e 131 Pfam PF02501 Type II secretion system (T2SS), protein I 54 129 7.8E-19 T 05-07-2017 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 K08M4_RS14220 82e65436d5de57dcfbcd8179bf12ee7e 131 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 19 38 3.7E-6 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS14220 82e65436d5de57dcfbcd8179bf12ee7e 131 TIGRFAM TIGR01707 gspI: type II secretion system protein I 20 117 4.5E-34 T 05-07-2017 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 K08M4_RS14220 82e65436d5de57dcfbcd8179bf12ee7e 131 Pfam PF13633 Prokaryotic N-terminal methylation site 19 44 1.2E-7 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS14220 82e65436d5de57dcfbcd8179bf12ee7e 131 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 19 39 - T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS14220 82e65436d5de57dcfbcd8179bf12ee7e 131 SUPERFAMILY SSF54523 51 129 3.73E-21 T 05-07-2017 K08M4_RS10815 2026923fa8e66ee25ca066ef8b2ee48b 304 Gene3D G3DSA:3.40.50.10190 214 297 2.0E-7 T 05-07-2017 IPR001357 BRCT domain K08M4_RS10815 2026923fa8e66ee25ca066ef8b2ee48b 304 SUPERFAMILY SSF52113 213 266 3.6E-5 T 05-07-2017 IPR001357 BRCT domain K08M4_RS04690 b4e94783b3a55854ef4aeb9e1382c8d4 93 Pfam PF07023 Protein of unknown function (DUF1315) 4 84 8.6E-31 T 05-07-2017 IPR009749 Protein of unknown function DUF1315 K08M4_RS06605 e02cb6ea6f3f1988b37e97775e802185 239 SUPERFAMILY SSF56935 35 239 1.71E-7 T 05-07-2017 K08M4_RS04315 6a21798bd6e612b422ad2b837e7860ae 183 ProSitePatterns PS00194 Thioredoxin family active site. 71 89 - T 05-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 K08M4_RS04315 6a21798bd6e612b422ad2b837e7860ae 183 SUPERFAMILY SSF52833 46 178 3.21E-38 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS04315 6a21798bd6e612b422ad2b837e7860ae 183 Pfam PF08534 Redoxin 42 165 1.0E-24 T 05-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 K08M4_RS04315 6a21798bd6e612b422ad2b837e7860ae 183 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 6 176 3.3E-70 T 05-07-2017 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 K08M4_RS04315 6a21798bd6e612b422ad2b837e7860ae 183 Gene3D G3DSA:3.40.30.10 10 177 7.1E-41 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS16340 f6179b40bfdea9a52a07ba09d9e4317a 345 Pfam PF01032 FecCD transport family 19 338 8.9E-90 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 K08M4_RS16340 f6179b40bfdea9a52a07ba09d9e4317a 345 Gene3D G3DSA:1.10.3470.10 11 343 1.0E-104 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS16340 f6179b40bfdea9a52a07ba09d9e4317a 345 SUPERFAMILY SSF81345 10 339 1.15E-82 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS16155 43329c3828c60d6c85fe2f4ade2731fa 385 Pfam PF07143 CrtC N-terminal lipocalin domain 83 258 2.9E-55 T 05-07-2017 IPR010791 AttH domain K08M4_RS16155 43329c3828c60d6c85fe2f4ade2731fa 385 SUPERFAMILY SSF159245 60 385 5.89E-103 T 05-07-2017 K08M4_RS16155 43329c3828c60d6c85fe2f4ade2731fa 385 Gene3D G3DSA:2.40.370.10 263 385 1.2E-42 T 05-07-2017 IPR023374 AttH-like domain K08M4_RS16155 43329c3828c60d6c85fe2f4ade2731fa 385 Pfam PF17186 Lipocalin-like domain 263 385 3.7E-40 T 05-07-2017 IPR033451 AttH, lipocalin-like domain K08M4_RS16155 43329c3828c60d6c85fe2f4ade2731fa 385 Gene3D G3DSA:2.40.370.10 71 261 1.9E-75 T 05-07-2017 IPR023374 AttH-like domain K08M4_RS13435 f985f562599fbd1574cd214ec43e856a 139 SUPERFAMILY SSF111038 1 139 1.31E-50 T 05-07-2017 IPR001602 Uncharacterised protein family UPF0047 K08M4_RS13435 f985f562599fbd1574cd214ec43e856a 139 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 100 118 - T 05-07-2017 IPR001602 Uncharacterised protein family UPF0047 K08M4_RS13435 f985f562599fbd1574cd214ec43e856a 139 Gene3D G3DSA:2.60.120.460 1 139 2.7E-59 T 05-07-2017 IPR001602 Uncharacterised protein family UPF0047 K08M4_RS13435 f985f562599fbd1574cd214ec43e856a 139 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 7 139 6.9E-47 T 05-07-2017 IPR001602 Uncharacterised protein family UPF0047 K08M4_RS13435 f985f562599fbd1574cd214ec43e856a 139 PIRSF PIRSF004681 1 139 7.4E-47 T 05-07-2017 IPR001602 Uncharacterised protein family UPF0047 K08M4_RS13435 f985f562599fbd1574cd214ec43e856a 139 Pfam PF01894 Uncharacterised protein family UPF0047 19 135 3.5E-40 T 05-07-2017 IPR001602 Uncharacterised protein family UPF0047 K08M4_RS15935 56b1611089d8c9cdf28d2b1eb2360a37 236 Pfam PF01048 Phosphorylase superfamily 17 217 3.8E-35 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 K08M4_RS15935 56b1611089d8c9cdf28d2b1eb2360a37 236 SUPERFAMILY SSF53167 3 234 6.28E-92 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 K08M4_RS15935 56b1611089d8c9cdf28d2b1eb2360a37 236 Gene3D G3DSA:3.40.50.1580 10 235 5.9E-83 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 K08M4_RS15935 56b1611089d8c9cdf28d2b1eb2360a37 236 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 2 235 51.589 T 05-07-2017 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 K08M4_RS15935 56b1611089d8c9cdf28d2b1eb2360a37 236 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 5 233 5.6E-113 T 05-07-2017 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 SUPERFAMILY SSF82693 39 131 6.28E-17 T 05-07-2017 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 Gene3D G3DSA:3.30.2090.10 724 797 7.0E-9 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 Gene3D G3DSA:3.30.2090.10 177 259 1.5E-17 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 Gene3D G3DSA:1.20.1640.10 280 488 2.2E-41 T 05-07-2017 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 PRINTS PR00702 Acriflavin resistance protein family signature 324 347 2.2E-21 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 2.2E-21 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 2.2E-21 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 PRINTS PR00702 Acriflavin resistance protein family signature 431 454 2.2E-21 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 PRINTS PR00702 Acriflavin resistance protein family signature 378 402 2.2E-21 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 Gene3D G3DSA:3.30.70.1430 39 131 6.2E-17 T 05-07-2017 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 SUPERFAMILY SSF82866 286 480 1.19E-33 T 05-07-2017 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 SUPERFAMILY SSF82693 139 175 6.28E-6 T 05-07-2017 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 SUPERFAMILY SSF82693 262 317 6.28E-6 T 05-07-2017 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 Gene3D G3DSA:3.30.70.1430 561 665 8.7E-4 T 05-07-2017 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 Pfam PF00873 AcrB/AcrD/AcrF family 1 1021 2.4E-154 T 05-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 SUPERFAMILY SSF82714 177 259 6.02E-16 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 Gene3D G3DSA:1.10.3850.10 804 1022 1.9E-59 T 05-07-2017 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 SUPERFAMILY SSF82866 797 1022 1.12E-46 T 05-07-2017 K08M4_RS12905 d6589c8349ee2b78dde442a2766abc98 1035 SUPERFAMILY SSF82714 724 797 2.09E-9 T 05-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains K08M4_RS00030 652c50d2e89f21a400f0f6cb029293ab 417 Pfam PF00155 Aminotransferase class I and II 67 400 1.5E-24 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS00030 652c50d2e89f21a400f0f6cb029293ab 417 SUPERFAMILY SSF53383 13 411 3.99E-60 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS00030 652c50d2e89f21a400f0f6cb029293ab 417 Gene3D G3DSA:3.40.640.10 56 267 8.9E-39 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS00030 652c50d2e89f21a400f0f6cb029293ab 417 Gene3D G3DSA:3.90.1150.10 268 410 1.0E-16 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS07480 262b1fddac70eaaf652806afa02107e6 268 Gene3D G3DSA:3.40.190.10 187 267 7.6E-27 T 05-07-2017 K08M4_RS07480 262b1fddac70eaaf652806afa02107e6 268 Pfam PF12849 PBP superfamily domain 28 245 5.7E-32 T 05-07-2017 IPR024370 PBP domain K08M4_RS07480 262b1fddac70eaaf652806afa02107e6 268 Gene3D G3DSA:3.40.190.10 12 152 1.3E-43 T 05-07-2017 K08M4_RS07480 262b1fddac70eaaf652806afa02107e6 268 SUPERFAMILY SSF53850 28 255 3.07E-33 T 05-07-2017 K08M4_RS19000 6d224758ddc55c51bbf662105d62e7eb 200 Pfam PF02661 Fic/DOC family 55 152 8.3E-18 T 05-07-2017 IPR003812 Fido domain K08M4_RS19000 6d224758ddc55c51bbf662105d62e7eb 200 Gene3D G3DSA:1.10.3290.10 11 199 5.3E-56 T 05-07-2017 IPR003812 Fido domain K08M4_RS19000 6d224758ddc55c51bbf662105d62e7eb 200 SUPERFAMILY SSF140931 45 195 1.7E-36 T 05-07-2017 IPR003812 Fido domain K08M4_RS15600 74b6c41f46cddfc8cec1abbb7fd4f2e5 265 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 260 6.4E-59 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS15600 74b6c41f46cddfc8cec1abbb7fd4f2e5 265 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 9 260 8.8E-52 T 05-07-2017 IPR000150 Cof protein GO:0016787 K08M4_RS15600 74b6c41f46cddfc8cec1abbb7fd4f2e5 265 ProSitePatterns PS01228 Hypothetical cof family signature 1. 8 19 - T 05-07-2017 IPR000150 Cof protein GO:0016787 K08M4_RS15600 74b6c41f46cddfc8cec1abbb7fd4f2e5 265 Gene3D G3DSA:3.40.50.1000 180 264 1.9E-49 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS15600 74b6c41f46cddfc8cec1abbb7fd4f2e5 265 Gene3D G3DSA:3.40.50.1000 3 76 1.9E-49 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS15600 74b6c41f46cddfc8cec1abbb7fd4f2e5 265 Gene3D G3DSA:3.30.1240.10 86 179 1.9E-30 T 05-07-2017 K08M4_RS15600 74b6c41f46cddfc8cec1abbb7fd4f2e5 265 SUPERFAMILY SSF56784 3 264 1.62E-68 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS15600 74b6c41f46cddfc8cec1abbb7fd4f2e5 265 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 9 231 4.0E-23 T 05-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 K08M4_RS15130 8bf5781ef286961a108529cf0b3c9e3b 609 SUPERFAMILY SSF56436 386 608 9.42E-53 T 05-07-2017 IPR016187 C-type lectin fold K08M4_RS15130 8bf5781ef286961a108529cf0b3c9e3b 609 Gene3D G3DSA:3.90.1580.10 383 608 4.3E-50 T 05-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 K08M4_RS15130 8bf5781ef286961a108529cf0b3c9e3b 609 Pfam PF03781 Sulfatase-modifying factor enzyme 1 386 607 5.2E-48 T 05-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 K08M4_RS15130 8bf5781ef286961a108529cf0b3c9e3b 609 Pfam PF08308 PEGA domain 300 363 4.0E-19 T 05-07-2017 IPR013229 PEGA K08M4_RS15650 0189495a4387dfdfcf7d6ac9d39be851 355 SUPERFAMILY SSF56281 35 300 1.96E-24 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS15650 0189495a4387dfdfcf7d6ac9d39be851 355 Pfam PF13483 Beta-lactamase superfamily domain 42 282 2.1E-12 T 05-07-2017 K08M4_RS15650 0189495a4387dfdfcf7d6ac9d39be851 355 Gene3D G3DSA:3.60.15.10 1 337 1.4E-118 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS19615 762c2358a509592e7f9d32438e1c35dd 691 Pfam PF00580 UvrD/REP helicase N-terminal domain 201 498 6.7E-44 T 05-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 K08M4_RS19615 762c2358a509592e7f9d32438e1c35dd 691 SUPERFAMILY SSF52540 390 679 1.08E-84 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19615 762c2358a509592e7f9d32438e1c35dd 691 SUPERFAMILY SSF52540 198 328 1.08E-84 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19615 762c2358a509592e7f9d32438e1c35dd 691 Pfam PF12462 DNA helicase IV / RNA helicase N terminal 1 166 5.4E-53 T 05-07-2017 IPR022161 DNA helicase IV, N-terminal domain K08M4_RS19615 762c2358a509592e7f9d32438e1c35dd 691 Pfam PF13361 UvrD-like helicase C-terminal domain 598 669 2.4E-17 T 05-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 K08M4_RS19615 762c2358a509592e7f9d32438e1c35dd 691 Gene3D G3DSA:3.40.50.300 199 341 1.3E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19615 762c2358a509592e7f9d32438e1c35dd 691 Gene3D G3DSA:3.40.50.300 400 502 1.3E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19615 762c2358a509592e7f9d32438e1c35dd 691 Gene3D G3DSA:3.40.50.300 508 683 2.0E-26 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16690 c503d1c638f92c5ae086d6b197c792e2 102 Pfam PF06945 Protein of unknown function (DUF1289) 3 45 5.2E-16 T 05-07-2017 IPR010710 Protein of unknown function DUF1289 K08M4_RS16690 c503d1c638f92c5ae086d6b197c792e2 102 Pfam PF14375 Cysteine-rich CWC 53 97 3.1E-6 T 05-07-2017 IPR032720 Cysteine-rich CWC K08M4_RS07910 fbb5a8a87365d42f63f6ef42bcc54265 365 SUPERFAMILY SSF161098 154 346 7.85E-41 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07910 fbb5a8a87365d42f63f6ef42bcc54265 365 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 173 357 1.6E-22 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07910 fbb5a8a87365d42f63f6ef42bcc54265 365 Gene3D G3DSA:1.10.3720.10 154 360 4.5E-45 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07910 fbb5a8a87365d42f63f6ef42bcc54265 365 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 155 251 1.6E-22 T 05-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 K08M4_RS13485 4e679d3b1bd9d60e641bfbbf7caa7919 469 SUPERFAMILY SSF51556 86 384 1.88E-81 T 05-07-2017 IPR032466 Metal-dependent hydrolase K08M4_RS13485 4e679d3b1bd9d60e641bfbbf7caa7919 469 Gene3D G3DSA:2.30.40.10 26 88 4.7E-22 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS13485 4e679d3b1bd9d60e641bfbbf7caa7919 469 Gene3D G3DSA:2.30.40.10 393 435 4.7E-22 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS13485 4e679d3b1bd9d60e641bfbbf7caa7919 469 Gene3D G3DSA:3.20.20.140 89 392 3.1E-86 T 05-07-2017 K08M4_RS13485 4e679d3b1bd9d60e641bfbbf7caa7919 469 Pfam PF01979 Amidohydrolase family 83 432 3.0E-68 T 05-07-2017 IPR006680 Amidohydrolase-related GO:0016787 K08M4_RS13485 4e679d3b1bd9d60e641bfbbf7caa7919 469 SUPERFAMILY SSF51338 383 455 6.72E-36 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS13485 4e679d3b1bd9d60e641bfbbf7caa7919 469 SUPERFAMILY SSF51338 29 86 6.72E-36 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS16660 fe968ff53720b9d84a14cad00c5d3a06 218 Hamap MF_01584 UPF0502 protein YceH [yceH]. 5 212 34.643 T 05-07-2017 IPR007432 Protein of unknown function DUF480 K08M4_RS16660 fe968ff53720b9d84a14cad00c5d3a06 218 Gene3D G3DSA:1.10.10.10 3 87 1.2E-38 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16660 fe968ff53720b9d84a14cad00c5d3a06 218 Gene3D G3DSA:1.10.10.10 95 174 5.4E-36 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16660 fe968ff53720b9d84a14cad00c5d3a06 218 Pfam PF04337 Protein of unknown function, DUF480 5 158 2.0E-64 T 05-07-2017 IPR007432 Protein of unknown function DUF480 K08M4_RS16660 fe968ff53720b9d84a14cad00c5d3a06 218 SUPERFAMILY SSF46785 3 84 3.26E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16660 fe968ff53720b9d84a14cad00c5d3a06 218 SUPERFAMILY SSF46785 90 174 2.0E-28 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS03060 618f4254c86977bc18951f2192af45ad 348 Pfam PF13609 Gram-negative porin 9 313 3.5E-25 T 05-07-2017 K08M4_RS03060 618f4254c86977bc18951f2192af45ad 348 SUPERFAMILY SSF56935 23 348 2.75E-51 T 05-07-2017 K08M4_RS03060 618f4254c86977bc18951f2192af45ad 348 Gene3D G3DSA:2.40.160.10 23 348 8.3E-58 T 05-07-2017 IPR023614 Porin domain K08M4_RS16885 72fea732920515300d687e95aac8c819 485 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 291 328 - T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 K08M4_RS16885 72fea732920515300d687e95aac8c819 485 Pfam PF00202 Aminotransferase class-III 62 475 2.3E-82 T 05-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 K08M4_RS16885 72fea732920515300d687e95aac8c819 485 Gene3D G3DSA:3.40.640.10 94 363 4.0E-62 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS16885 72fea732920515300d687e95aac8c819 485 Gene3D G3DSA:3.90.1150.10 364 478 1.2E-34 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS16885 72fea732920515300d687e95aac8c819 485 SUPERFAMILY SSF53383 62 215 1.24E-98 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS16885 72fea732920515300d687e95aac8c819 485 SUPERFAMILY SSF53383 242 476 1.24E-98 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS11865 1daad96a4b84ac233ff9352e0ec49dde 431 Gene3D G3DSA:3.40.630.10 95 429 2.0E-117 T 05-07-2017 K08M4_RS11865 1daad96a4b84ac233ff9352e0ec49dde 431 PIRSF PIRSF036388 1 431 8.8E-220 T 05-07-2017 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 K08M4_RS11865 1daad96a4b84ac233ff9352e0ec49dde 431 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 109 422 1.2E-100 T 05-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 K08M4_RS11865 1daad96a4b84ac233ff9352e0ec49dde 431 Pfam PF12404 Peptidase 5 81 2.0E-31 T 05-07-2017 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 K08M4_RS11865 1daad96a4b84ac233ff9352e0ec49dde 431 PRINTS PR00481 Cytosol aminopeptidase signature 213 234 1.8E-46 T 05-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 K08M4_RS11865 1daad96a4b84ac233ff9352e0ec49dde 431 PRINTS PR00481 Cytosol aminopeptidase signature 250 271 1.8E-46 T 05-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 K08M4_RS11865 1daad96a4b84ac233ff9352e0ec49dde 431 PRINTS PR00481 Cytosol aminopeptidase signature 191 208 1.8E-46 T 05-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 K08M4_RS11865 1daad96a4b84ac233ff9352e0ec49dde 431 PRINTS PR00481 Cytosol aminopeptidase signature 272 292 1.8E-46 T 05-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 K08M4_RS11865 1daad96a4b84ac233ff9352e0ec49dde 431 PRINTS PR00481 Cytosol aminopeptidase signature 300 315 1.8E-46 T 05-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 K08M4_RS11865 1daad96a4b84ac233ff9352e0ec49dde 431 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 276 283 - T 05-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 K08M4_RS11865 1daad96a4b84ac233ff9352e0ec49dde 431 SUPERFAMILY SSF53187 105 428 1.48E-101 T 05-07-2017 K08M4_RS11865 1daad96a4b84ac233ff9352e0ec49dde 431 Hamap MF_00504 Peptidase B [pepB]. 3 428 64.794 T 05-07-2017 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 K08M4_RS13085 d20679fa06934135ec96758074661240 1290 Pfam PF13116 Protein of unknown function 505 791 5.2E-91 T 05-07-2017 IPR025263 Domain of unknown function DUF3971 K08M4_RS13085 d20679fa06934135ec96758074661240 1290 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 9 1278 0.0 T 05-07-2017 IPR011836 Conserved hypothetical protein CHP02099 K08M4_RS13085 d20679fa06934135ec96758074661240 1290 Pfam PF13502 AsmA-like C-terminal region 1028 1268 4.1E-61 T 05-07-2017 IPR032712 AsmA-like, C-terminal K08M4_RS13095 958c1ce127c81660e0a0dee84c313090 193 PIRSF PIRSF006305 1 193 1.2E-55 T 05-07-2017 IPR003697 Maf-like protein GO:0005737 K08M4_RS13095 958c1ce127c81660e0a0dee84c313090 193 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 190 5.1E-52 T 05-07-2017 IPR003697 Maf-like protein GO:0005737 K08M4_RS13095 958c1ce127c81660e0a0dee84c313090 193 Gene3D G3DSA:3.90.950.10 4 192 7.9E-68 T 05-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like K08M4_RS13095 958c1ce127c81660e0a0dee84c313090 193 Pfam PF02545 Maf-like protein 5 191 1.3E-58 T 05-07-2017 IPR003697 Maf-like protein GO:0005737 K08M4_RS13095 958c1ce127c81660e0a0dee84c313090 193 SUPERFAMILY SSF52972 3 191 1.05E-59 T 05-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like K08M4_RS13095 958c1ce127c81660e0a0dee84c313090 193 Hamap MF_00528 Septum formation protein Maf [maf]. 5 193 28.554 T 05-07-2017 IPR003697 Maf-like protein GO:0005737 K08M4_RS00865 b4ae00162f35d9354f63e9459500da75 195 Gene3D G3DSA:1.20.1590.10 1 194 1.8E-84 T 05-07-2017 IPR023381 YP001051499.1-like domain K08M4_RS00865 b4ae00162f35d9354f63e9459500da75 195 Pfam PF04222 Protein of unknown function (DUF416) 6 193 8.9E-76 T 05-07-2017 IPR007338 Protein of unknown function DUF416 K08M4_RS05485 36084e3c35dc8dc4cfafdc41efc23c53 319 Gene3D G3DSA:3.30.470.20 39 101 8.4E-6 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS05485 36084e3c35dc8dc4cfafdc41efc23c53 319 Pfam PF14397 Sugar-transfer associated ATP-grasp 21 295 1.4E-114 T 05-07-2017 K08M4_RS05485 36084e3c35dc8dc4cfafdc41efc23c53 319 SUPERFAMILY SSF56059 232 280 1.33E-19 T 05-07-2017 K08M4_RS05485 36084e3c35dc8dc4cfafdc41efc23c53 319 SUPERFAMILY SSF56059 43 202 1.33E-19 T 05-07-2017 K08M4_RS05485 36084e3c35dc8dc4cfafdc41efc23c53 319 Gene3D G3DSA:3.30.470.20 225 285 1.4E-5 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS05485 36084e3c35dc8dc4cfafdc41efc23c53 319 Gene3D G3DSA:3.30.470.20 162 203 2.8E-4 T 05-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 K08M4_RS05485 36084e3c35dc8dc4cfafdc41efc23c53 319 TIGRFAM TIGR02291 rimK_rel_E_lig: alpha-L-glutamate ligase homolog 5 319 2.4E-169 T 05-07-2017 IPR011758 Alpha-L-glutamate ligase-related protein K08M4_RS03430 96543717087c3ab8e0e2bec4678f14fb 184 SUPERFAMILY SSF110857 1 123 5.62E-15 T 05-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like K08M4_RS03430 96543717087c3ab8e0e2bec4678f14fb 184 Gene3D G3DSA:3.10.490.10 1 146 5.9E-11 T 05-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like K08M4_RS03430 96543717087c3ab8e0e2bec4678f14fb 184 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 3 108 5.5E-8 T 05-07-2017 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like K08M4_RS12255 fe7e018bf988fc40282a3f6ad77deacc 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 3.2E-31 T 05-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS12255 fe7e018bf988fc40282a3f6ad77deacc 86 Gene3D G3DSA:1.20.58.110 1 86 4.4E-32 T 05-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS12255 fe7e018bf988fc40282a3f6ad77deacc 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.563 T 05-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS12255 fe7e018bf988fc40282a3f6ad77deacc 86 SUPERFAMILY SSF46992 3 86 4.58E-32 T 05-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS12255 fe7e018bf988fc40282a3f6ad77deacc 86 Pfam PF01649 Ribosomal protein S20 2 84 2.7E-28 T 05-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS12255 fe7e018bf988fc40282a3f6ad77deacc 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 13 86 4.0E-28 T 05-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01490 e35764de2ef3a53de7ed971d778c2e6d 110 Gene3D G3DSA:3.90.470.10 1 109 2.6E-45 T 05-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 K08M4_RS01490 e35764de2ef3a53de7ed971d778c2e6d 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 29.523 T 05-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01490 e35764de2ef3a53de7ed971d778c2e6d 110 SUPERFAMILY SSF54843 1 109 1.15E-44 T 05-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 K08M4_RS01490 e35764de2ef3a53de7ed971d778c2e6d 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 05-07-2017 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01490 e35764de2ef3a53de7ed971d778c2e6d 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 2.8E-49 T 05-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01490 e35764de2ef3a53de7ed971d778c2e6d 110 Pfam PF00237 Ribosomal protein L22p/L17e 9 107 6.9E-35 T 05-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 K08M4_RS08825 137a5eb5f0d5efec25334e6beb84c335 82 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 11 77 2.9E-8 T 05-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM K08M4_RS08825 137a5eb5f0d5efec25334e6beb84c335 82 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 12 61 3.6E-5 T 05-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM K08M4_RS08825 137a5eb5f0d5efec25334e6beb84c335 82 SUPERFAMILY SSF143120 12 68 3.66E-8 T 05-07-2017 K08M4_RS06640 35f8208bf9e4e220a2cbd112f1c1511f 356 Gene3D G3DSA:3.30.70.270 184 345 3.2E-41 T 05-07-2017 K08M4_RS06640 35f8208bf9e4e220a2cbd112f1c1511f 356 Gene3D G3DSA:3.30.450.40 12 179 3.2E-17 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS06640 35f8208bf9e4e220a2cbd112f1c1511f 356 Pfam PF00990 Diguanylate cyclase, GGDEF domain 182 343 1.1E-35 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS06640 35f8208bf9e4e220a2cbd112f1c1511f 356 Pfam PF01590 GAF domain 39 162 1.3E-8 T 05-07-2017 IPR003018 GAF domain GO:0005515 K08M4_RS06640 35f8208bf9e4e220a2cbd112f1c1511f 356 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 178 344 1.4E-36 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS06640 35f8208bf9e4e220a2cbd112f1c1511f 356 SUPERFAMILY SSF55781 32 175 1.96E-16 T 05-07-2017 IPR029016 GAF domain-like K08M4_RS06640 35f8208bf9e4e220a2cbd112f1c1511f 356 SMART SM00267 171 347 8.6E-52 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS06640 35f8208bf9e4e220a2cbd112f1c1511f 356 SUPERFAMILY SSF55073 187 345 1.1E-35 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS08585 2843b2438a28c749a5afb571450b5d22 238 Gene3D G3DSA:3.30.420.10 40 229 2.0E-43 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS08585 2843b2438a28c749a5afb571450b5d22 238 Pfam PF00929 Exonuclease 50 219 1.5E-13 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS08585 2843b2438a28c749a5afb571450b5d22 238 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 47 228 2.0E-21 T 05-07-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS08585 2843b2438a28c749a5afb571450b5d22 238 SUPERFAMILY SSF53098 39 227 1.66E-38 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS08585 2843b2438a28c749a5afb571450b5d22 238 SMART SM00479 47 228 1.8E-19 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS09480 f6bee765d23186a1cc1b8d4dc3c2c0f1 204 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 5 204 33.121 T 05-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 K08M4_RS09480 f6bee765d23186a1cc1b8d4dc3c2c0f1 204 PIRSF PIRSF000495 4 204 6.0E-64 T 05-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 K08M4_RS09480 f6bee765d23186a1cc1b8d4dc3c2c0f1 204 SUPERFAMILY SSF52317 5 203 7.73E-52 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS09480 f6bee765d23186a1cc1b8d4dc3c2c0f1 204 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 6 203 8.0E-68 T 05-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 K08M4_RS09480 f6bee765d23186a1cc1b8d4dc3c2c0f1 204 Gene3D G3DSA:3.40.50.880 2 204 1.4E-68 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS09480 f6bee765d23186a1cc1b8d4dc3c2c0f1 204 Pfam PF00117 Glutamine amidotransferase class-I 8 202 2.5E-16 T 05-07-2017 IPR017926 Glutamine amidotransferase K08M4_RS01665 e81507aca16e5a4822685a4842e7cccf 302 PIRSF PIRSF002936 1 302 6.8E-156 T 05-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 K08M4_RS01665 e81507aca16e5a4822685a4842e7cccf 302 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 29 257 3.5E-63 T 05-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 K08M4_RS01665 e81507aca16e5a4822685a4842e7cccf 302 SUPERFAMILY SSF52402 6 209 7.39E-74 T 05-07-2017 K08M4_RS01665 e81507aca16e5a4822685a4842e7cccf 302 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 4 302 57.944 T 05-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 K08M4_RS01665 e81507aca16e5a4822685a4842e7cccf 302 Gene3D G3DSA:3.40.50.620 3 210 7.8E-63 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS01665 e81507aca16e5a4822685a4842e7cccf 302 Gene3D G3DSA:3.40.50.620 244 253 7.8E-63 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS01665 e81507aca16e5a4822685a4842e7cccf 302 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 9 302 2.2E-162 T 05-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 K08M4_RS11715 f225d42aa336ae90542fb34b4316c08b 554 PIRSF PIRSF003128 1 554 2.7E-163 T 05-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 K08M4_RS11715 f225d42aa336ae90542fb34b4316c08b 554 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 551 5.3E-173 T 05-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 K08M4_RS11715 f225d42aa336ae90542fb34b4316c08b 554 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 503 4.1E-18 T 05-07-2017 IPR003395 RecF/RecN/SMC, N-terminal K08M4_RS11715 f225d42aa336ae90542fb34b4316c08b 554 Gene3D G3DSA:3.40.50.300 431 505 1.8E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11715 f225d42aa336ae90542fb34b4316c08b 554 SUPERFAMILY SSF52540 1 199 1.49E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11715 f225d42aa336ae90542fb34b4316c08b 554 SUPERFAMILY SSF52540 351 510 1.49E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11715 f225d42aa336ae90542fb34b4316c08b 554 SUPERFAMILY SSF52540 287 322 1.49E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS11715 f225d42aa336ae90542fb34b4316c08b 554 Gene3D G3DSA:3.40.50.300 1 205 2.2E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12605 28c29fe8745c65270e2b349d7fc26223 105 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 20 102 3.6E-24 T 05-07-2017 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 K08M4_RS12605 28c29fe8745c65270e2b349d7fc26223 105 Pfam PF04999 Cell division protein FtsL 8 103 2.7E-35 T 05-07-2017 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 K08M4_RS12605 28c29fe8745c65270e2b349d7fc26223 105 Hamap MF_00910 Cell division protein FtsL [ftsL]. 19 102 15.096 T 05-07-2017 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 K08M4_RS04525 dadc71da1922fa1c53327e9fd6409803 403 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 358 3.9E-27 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal K08M4_RS04525 dadc71da1922fa1c53327e9fd6409803 403 Gene3D G3DSA:3.40.47.10 6 257 1.0E-61 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS04525 dadc71da1922fa1c53327e9fd6409803 403 Gene3D G3DSA:3.40.47.10 261 402 4.3E-49 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS04525 dadc71da1922fa1c53327e9fd6409803 403 SUPERFAMILY SSF53901 1 251 8.35E-66 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS04525 dadc71da1922fa1c53327e9fd6409803 403 SMART SM00825 Beta-ketoacyl synthase 4 403 1.8E-13 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain K08M4_RS04525 dadc71da1922fa1c53327e9fd6409803 403 SUPERFAMILY SSF53901 213 401 4.94E-60 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS04525 dadc71da1922fa1c53327e9fd6409803 403 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 244 1.6E-44 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal K08M4_RS04525 dadc71da1922fa1c53327e9fd6409803 403 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 152 168 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site K08M4_RS11315 f6ecad92b199d8ceec2cb49d7d22f30f 229 Gene3D G3DSA:1.10.3680.10 84 227 9.7E-27 T 05-07-2017 IPR029024 TerB-like K08M4_RS11315 f6ecad92b199d8ceec2cb49d7d22f30f 229 SUPERFAMILY SSF158682 85 227 3.27E-24 T 05-07-2017 IPR029024 TerB-like K08M4_RS11315 f6ecad92b199d8ceec2cb49d7d22f30f 229 Pfam PF04391 Protein of unknown function (DUF533) 51 227 7.7E-61 T 05-07-2017 IPR007486 Inner membrane protein YebE K08M4_RS21660 229af21f8d757847f2ddd9351b1f1ddb 232 SUPERFAMILY SSF51735 17 230 1.31E-42 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS21660 229af21f8d757847f2ddd9351b1f1ddb 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 1.9E-20 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS21660 229af21f8d757847f2ddd9351b1f1ddb 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 158 1.9E-20 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS21660 229af21f8d757847f2ddd9351b1f1ddb 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 175 1.9E-20 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS21660 229af21f8d757847f2ddd9351b1f1ddb 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.9E-20 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS21660 229af21f8d757847f2ddd9351b1f1ddb 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 215 1.9E-20 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS21660 229af21f8d757847f2ddd9351b1f1ddb 232 Gene3D G3DSA:3.40.50.720 15 226 2.6E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS21660 229af21f8d757847f2ddd9351b1f1ddb 232 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 52 228 5.3E-31 T 05-07-2017 K08M4_RS15050 37608b5d9baae8226ef50500ad116457 311 Gene3D G3DSA:1.20.58.340 152 230 6.5E-7 T 05-07-2017 K08M4_RS15050 37608b5d9baae8226ef50500ad116457 311 SUPERFAMILY SSF144083 246 308 1.44E-11 T 05-07-2017 K08M4_RS15050 37608b5d9baae8226ef50500ad116457 311 SUPERFAMILY SSF143865 6 235 7.32E-33 T 05-07-2017 K08M4_RS15050 37608b5d9baae8226ef50500ad116457 311 Gene3D G3DSA:1.20.58.340 238 310 1.6E-15 T 05-07-2017 K08M4_RS15050 37608b5d9baae8226ef50500ad116457 311 Pfam PF01544 CorA-like Mg2+ transporter protein 28 306 8.6E-48 T 05-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 K08M4_RS01300 a2300f850ca49787f51f9e8c6cd745d6 224 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 216 3.3E-101 T 05-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 K08M4_RS01300 a2300f850ca49787f51f9e8c6cd745d6 224 Gene3D G3DSA:3.20.20.70 2 221 7.0E-99 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS01300 a2300f850ca49787f51f9e8c6cd745d6 224 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 136 158 - T 05-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 K08M4_RS01300 a2300f850ca49787f51f9e8c6cd745d6 224 PIRSF PIRSF001461 1 224 7.0E-108 T 05-07-2017 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 K08M4_RS01300 a2300f850ca49787f51f9e8c6cd745d6 224 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 203 1.5E-92 T 05-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 K08M4_RS01300 a2300f850ca49787f51f9e8c6cd745d6 224 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 05-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 K08M4_RS01300 a2300f850ca49787f51f9e8c6cd745d6 224 SUPERFAMILY SSF51366 4 218 3.19E-79 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 K08M4_RS18845 aaef0091bb520ab2daabf2ccab084e8f 81 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 3 76 2.8E-28 T 05-07-2017 IPR018680 Protein of unknown function DUF2164 K08M4_RS20165 a3610bda76280471fb01386b37827b01 341 SMART SM00829 20 339 4.2E-11 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 K08M4_RS20165 a3610bda76280471fb01386b37827b01 341 SUPERFAMILY SSF51735 125 287 2.31E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS20165 a3610bda76280471fb01386b37827b01 341 Pfam PF13602 Zinc-binding dehydrogenase 199 337 2.4E-16 T 05-07-2017 K08M4_RS20165 a3610bda76280471fb01386b37827b01 341 SUPERFAMILY SSF50129 15 154 5.48E-32 T 05-07-2017 IPR011032 GroES-like K08M4_RS20165 a3610bda76280471fb01386b37827b01 341 Gene3D G3DSA:3.90.180.10 6 161 1.0E-35 T 05-07-2017 IPR011032 GroES-like K08M4_RS20165 a3610bda76280471fb01386b37827b01 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 37 98 7.8E-8 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 K08M4_RS20165 a3610bda76280471fb01386b37827b01 341 Gene3D G3DSA:3.40.50.720 162 251 1.4E-17 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS20165 a3610bda76280471fb01386b37827b01 341 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 8 338 1.6E-116 T 05-07-2017 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 K08M4_RS12580 8717a143e10b0670b14dd0ea3901f911 438 Gene3D G3DSA:3.40.50.720 8 96 1.5E-17 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS12580 8717a143e10b0670b14dd0ea3901f911 438 SUPERFAMILY SSF51984 8 97 5.23E-16 T 05-07-2017 K08M4_RS12580 8717a143e10b0670b14dd0ea3901f911 438 Gene3D G3DSA:3.40.1190.10 97 299 1.8E-61 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS12580 8717a143e10b0670b14dd0ea3901f911 438 SUPERFAMILY SSF53244 299 437 8.24E-40 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS12580 8717a143e10b0670b14dd0ea3901f911 438 Gene3D G3DSA:3.90.190.20 301 433 2.7E-39 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS12580 8717a143e10b0670b14dd0ea3901f911 438 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 9 435 3.3E-128 T 05-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS12580 8717a143e10b0670b14dd0ea3901f911 438 Pfam PF08245 Mur ligase middle domain 113 279 1.5E-29 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS12580 8717a143e10b0670b14dd0ea3901f911 438 SUPERFAMILY SSF53623 99 297 3.92E-53 T 05-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 K08M4_RS12580 8717a143e10b0670b14dd0ea3901f911 438 Pfam PF02875 Mur ligase family, glutamate ligase domain 302 375 1.8E-5 T 05-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 K08M4_RS12580 8717a143e10b0670b14dd0ea3901f911 438 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 8 437 32.154 T 05-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS00435 30f488463bf7a868eae181f58f5f97cb 310 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 19 306 7.9E-106 T 05-07-2017 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 K08M4_RS00435 30f488463bf7a868eae181f58f5f97cb 310 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 18 100 5.1E-20 T 05-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 K08M4_RS00435 30f488463bf7a868eae181f58f5f97cb 310 Gene3D G3DSA:1.10.443.10 123 298 2.6E-49 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS00435 30f488463bf7a868eae181f58f5f97cb 310 Pfam PF00589 Phage integrase family 122 290 2.1E-45 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS00435 30f488463bf7a868eae181f58f5f97cb 310 Gene3D G3DSA:1.10.150.130 14 110 6.3E-22 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal K08M4_RS00435 30f488463bf7a868eae181f58f5f97cb 310 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 15 304 55.102 T 05-07-2017 IPR023009 Tyrosine recombinase XerC/XerD K08M4_RS00435 30f488463bf7a868eae181f58f5f97cb 310 SUPERFAMILY SSF56349 15 298 1.53E-52 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS07995 ad82825896a3be71b5dcf116aecf2bfb 133 Pfam PF13488 Glycine zipper 36 76 1.2E-5 T 05-07-2017 K08M4_RS01175 15eba29a376f9e2a4f11e33f4aa2812a 803 PIRSF PIRSF000727 5 803 8.7E-287 T 05-07-2017 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+2.7.2.4+1.1.1.3|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4+1.1.1.3|KEGG: 00300+2.7.2.4+1.1.1.3|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS01175 15eba29a376f9e2a4f11e33f4aa2812a 803 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 8 445 2.6E-66 T 05-07-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS01175 15eba29a376f9e2a4f11e33f4aa2812a 803 SUPERFAMILY SSF55347 601 784 2.48E-46 T 05-07-2017 K08M4_RS01175 15eba29a376f9e2a4f11e33f4aa2812a 803 Gene3D G3DSA:3.30.360.10 623 779 2.7E-51 T 05-07-2017 K08M4_RS01175 15eba29a376f9e2a4f11e33f4aa2812a 803 Gene3D G3DSA:3.40.1160.10 106 290 1.1E-45 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS01175 15eba29a376f9e2a4f11e33f4aa2812a 803 Gene3D G3DSA:3.40.1160.10 5 52 1.1E-45 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS01175 15eba29a376f9e2a4f11e33f4aa2812a 803 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 647 669 - T 05-07-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 K08M4_RS01175 15eba29a376f9e2a4f11e33f4aa2812a 803 ProSitePatterns PS00324 Aspartokinase signature. 7 15 - T 05-07-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 K08M4_RS01175 15eba29a376f9e2a4f11e33f4aa2812a 803 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 457 593 7.1E-14 T 05-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 K08M4_RS01175 15eba29a376f9e2a4f11e33f4aa2812a 803 SUPERFAMILY SSF51735 448 623 7.27E-34 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS01175 15eba29a376f9e2a4f11e33f4aa2812a 803 Pfam PF00742 Homoserine dehydrogenase 601 796 1.5E-43 T 05-07-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 K08M4_RS01175 15eba29a376f9e2a4f11e33f4aa2812a 803 Pfam PF00696 Amino acid kinase family 6 274 1.8E-41 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS01175 15eba29a376f9e2a4f11e33f4aa2812a 803 SUPERFAMILY SSF53633 6 291 3.67E-57 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS01175 15eba29a376f9e2a4f11e33f4aa2812a 803 Gene3D G3DSA:3.40.50.720 448 622 4.8E-48 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS18000 7de3d622a3745dfb9b16e009db6a0de2 388 SUPERFAMILY SSF46626 35 182 1.65E-36 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS18000 7de3d622a3745dfb9b16e009db6a0de2 388 PIRSF PIRSF000294 26 380 9.4E-71 T 05-07-2017 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 K08M4_RS18000 7de3d622a3745dfb9b16e009db6a0de2 388 SUPERFAMILY SSF46626 283 358 5.49E-31 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS18000 7de3d622a3745dfb9b16e009db6a0de2 388 SUPERFAMILY SSF46626 173 237 5.49E-31 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS18000 7de3d622a3745dfb9b16e009db6a0de2 388 Gene3D G3DSA:1.10.760.10 188 370 7.6E-44 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS18000 7de3d622a3745dfb9b16e009db6a0de2 388 Pfam PF03150 Di-haem cytochrome c peroxidase 49 196 1.5E-35 T 05-07-2017 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 K08M4_RS18000 7de3d622a3745dfb9b16e009db6a0de2 388 Gene3D G3DSA:1.10.760.10 39 187 3.1E-37 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS15395 3ca29a8af816b02eeec34354116a08e2 502 SUPERFAMILY SSF53850 126 499 2.78E-33 T 05-07-2017 K08M4_RS15395 3ca29a8af816b02eeec34354116a08e2 502 Pfam PF12793 Sugar transport-related sRNA regulator N-term 8 114 3.3E-24 T 05-07-2017 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain K08M4_RS15395 3ca29a8af816b02eeec34354116a08e2 502 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 164 320 1.3E-18 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain K08M4_RS15395 3ca29a8af816b02eeec34354116a08e2 502 Gene3D G3DSA:3.90.76.10 133 274 1.1E-17 T 05-07-2017 K08M4_RS15395 3ca29a8af816b02eeec34354116a08e2 502 Gene3D G3DSA:1.10.10.10 25 100 9.6E-4 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS04665 980bffb355e61031e1a26b5f9ba359fd 678 SUPERFAMILY SSF58104 378 677 2.49E-65 T 05-07-2017 K08M4_RS04665 980bffb355e61031e1a26b5f9ba359fd 678 Gene3D G3DSA:3.30.450.20 173 324 1.7E-15 T 05-07-2017 K08M4_RS04665 980bffb355e61031e1a26b5f9ba359fd 678 SUPERFAMILY SSF103190 115 211 4.32E-11 T 05-07-2017 IPR029151 Periplasmic sensor domain-like K08M4_RS04665 980bffb355e61031e1a26b5f9ba359fd 678 Pfam PF17201 Cache 3/Cache 2 fusion domain 37 324 8.8E-67 T 05-07-2017 IPR033462 Cache 3/Cache 2 fusion domain K08M4_RS04665 980bffb355e61031e1a26b5f9ba359fd 678 SMART SM00283 417 678 3.7E-69 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS04665 980bffb355e61031e1a26b5f9ba359fd 678 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 438 467 1.2E-20 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS04665 980bffb355e61031e1a26b5f9ba359fd 678 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 515 542 1.2E-20 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS04665 980bffb355e61031e1a26b5f9ba359fd 678 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 544 573 1.2E-20 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS04665 980bffb355e61031e1a26b5f9ba359fd 678 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 484 677 7.2E-48 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS04665 980bffb355e61031e1a26b5f9ba359fd 678 SMART SM00304 347 402 9.5E-4 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS04665 980bffb355e61031e1a26b5f9ba359fd 678 Gene3D G3DSA:1.10.287.950 432 648 1.9E-52 T 05-07-2017 K08M4_RS20800 f9d60aa54c53376e3e609c4247a28873 239 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 K08M4_RS20800 f9d60aa54c53376e3e609c4247a28873 239 SUPERFAMILY SSF51735 3 223 4.68E-61 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS20800 f9d60aa54c53376e3e609c4247a28873 239 Gene3D G3DSA:3.40.50.720 2 224 4.0E-65 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS20800 f9d60aa54c53376e3e609c4247a28873 239 Pfam PF00106 short chain dehydrogenase 3 189 7.2E-52 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS20800 f9d60aa54c53376e3e609c4247a28873 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 1.7E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS20800 f9d60aa54c53376e3e609c4247a28873 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 1.7E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS20800 f9d60aa54c53376e3e609c4247a28873 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 1.7E-9 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS20800 f9d60aa54c53376e3e609c4247a28873 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 2.3E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS20800 f9d60aa54c53376e3e609c4247a28873 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.3E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS20800 f9d60aa54c53376e3e609c4247a28873 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 2.3E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS20800 f9d60aa54c53376e3e609c4247a28873 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 2.3E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS20800 f9d60aa54c53376e3e609c4247a28873 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 2.3E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS20800 f9d60aa54c53376e3e609c4247a28873 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 2.3E-31 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS15740 910823b4b6f4f5d127fcc5d15b79a81d 657 Pfam PF00128 Alpha amylase, catalytic domain 199 253 3.4E-5 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS15740 910823b4b6f4f5d127fcc5d15b79a81d 657 Gene3D G3DSA:2.60.40.1180 557 642 1.1E-8 T 05-07-2017 IPR013780 Glycosyl hydrolase, all-beta K08M4_RS15740 910823b4b6f4f5d127fcc5d15b79a81d 657 SUPERFAMILY SSF51445 471 542 2.71E-98 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS15740 910823b4b6f4f5d127fcc5d15b79a81d 657 SUPERFAMILY SSF51445 113 442 2.71E-98 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS15740 910823b4b6f4f5d127fcc5d15b79a81d 657 Gene3D G3DSA:2.60.40.10 7 130 2.2E-23 T 05-07-2017 IPR013783 Immunoglobulin-like fold K08M4_RS15740 910823b4b6f4f5d127fcc5d15b79a81d 657 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 87 1.1E-8 T 05-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 K08M4_RS15740 910823b4b6f4f5d127fcc5d15b79a81d 657 SUPERFAMILY SSF81296 7 124 1.4E-23 T 05-07-2017 IPR014756 Immunoglobulin E-set K08M4_RS15740 910823b4b6f4f5d127fcc5d15b79a81d 657 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 7 637 1.6E-198 T 05-07-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 K08M4_RS15740 910823b4b6f4f5d127fcc5d15b79a81d 657 SMART SM00642 145 539 2.0E-4 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS15740 910823b4b6f4f5d127fcc5d15b79a81d 657 Gene3D G3DSA:3.20.20.80 131 542 5.1E-85 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS15740 910823b4b6f4f5d127fcc5d15b79a81d 657 SUPERFAMILY SSF51011 556 647 4.53E-14 T 05-07-2017 K08M4_RS05105 fcfdaf820eec87d483def9cc917d367f 341 Pfam PF02504 Fatty acid synthesis protein 5 327 4.8E-101 T 05-07-2017 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 K08M4_RS05105 fcfdaf820eec87d483def9cc917d367f 341 PIRSF PIRSF002465 2 339 7.8E-124 T 05-07-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 K08M4_RS05105 fcfdaf820eec87d483def9cc917d367f 341 Gene3D G3DSA:3.40.718.10 3 335 1.5E-126 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 K08M4_RS05105 fcfdaf820eec87d483def9cc917d367f 341 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 6 335 8.3E-108 T 05-07-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 K08M4_RS05105 fcfdaf820eec87d483def9cc917d367f 341 SUPERFAMILY SSF53659 4 336 1.03E-102 T 05-07-2017 K08M4_RS05105 fcfdaf820eec87d483def9cc917d367f 341 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 340 136.16 T 05-07-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 K08M4_RS06230 82b4aab83a5e3dcbfdd5b1468e59e18d 620 SUPERFAMILY SSF54631 155 273 4.8E-25 T 05-07-2017 K08M4_RS06230 82b4aab83a5e3dcbfdd5b1468e59e18d 620 Gene3D G3DSA:2.60.120.10 7 141 4.9E-16 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS06230 82b4aab83a5e3dcbfdd5b1468e59e18d 620 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 474 617 3.7E-40 T 05-07-2017 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding K08M4_RS06230 82b4aab83a5e3dcbfdd5b1468e59e18d 620 SMART SM00116 165 212 11.0 T 05-07-2017 IPR000644 CBS domain K08M4_RS06230 82b4aab83a5e3dcbfdd5b1468e59e18d 620 SMART SM00116 229 276 2.4E-7 T 05-07-2017 IPR000644 CBS domain K08M4_RS06230 82b4aab83a5e3dcbfdd5b1468e59e18d 620 Pfam PF03445 Putative nucleotidyltransferase DUF294 303 435 2.0E-42 T 05-07-2017 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 K08M4_RS06230 82b4aab83a5e3dcbfdd5b1468e59e18d 620 Gene3D G3DSA:3.10.580.10 155 273 3.1E-27 T 05-07-2017 K08M4_RS06230 82b4aab83a5e3dcbfdd5b1468e59e18d 620 Pfam PF00571 CBS domain 222 273 4.4E-10 T 05-07-2017 IPR000644 CBS domain K08M4_RS06230 82b4aab83a5e3dcbfdd5b1468e59e18d 620 SUPERFAMILY SSF51206 8 133 3.27E-15 T 05-07-2017 IPR018490 Cyclic nucleotide-binding-like K08M4_RS01340 1d45286acdcc60fc4041ccd78ba6ff7d 485 Gene3D G3DSA:3.40.309.10 257 442 6.0E-44 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 K08M4_RS01340 1d45286acdcc60fc4041ccd78ba6ff7d 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 271 282 - T 05-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 K08M4_RS01340 1d45286acdcc60fc4041ccd78ba6ff7d 485 SUPERFAMILY SSF53720 3 449 1.31E-121 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 K08M4_RS01340 1d45286acdcc60fc4041ccd78ba6ff7d 485 TIGRFAM TIGR03240 arg_catab_astD: succinylglutamate-semialdehyde dehydrogenase 3 484 6.9E-225 T 05-07-2017 IPR017649 Succinylglutamate-semialdehyde dehydrogenase GO:0006527|GO:0043824|GO:0055114 KEGG: 00330+1.2.1.71 K08M4_RS01340 1d45286acdcc60fc4041ccd78ba6ff7d 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 242 249 - T 05-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 K08M4_RS01340 1d45286acdcc60fc4041ccd78ba6ff7d 485 Gene3D G3DSA:3.40.605.10 4 256 1.0E-73 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS01340 1d45286acdcc60fc4041ccd78ba6ff7d 485 Pfam PF00171 Aldehyde dehydrogenase family 9 458 6.2E-120 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS01340 1d45286acdcc60fc4041ccd78ba6ff7d 485 Hamap MF_01174 N-succinylglutamate 5-semialdehyde dehydrogenase [astD]. 1 485 55.755 T 05-07-2017 IPR017649 Succinylglutamate-semialdehyde dehydrogenase GO:0006527|GO:0043824|GO:0055114 KEGG: 00330+1.2.1.71 K08M4_RS16850 1b87426f03b30af739a7bbf34a038cd0 371 SUPERFAMILY SSF82861 98 179 2.35E-13 T 05-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 K08M4_RS16850 1b87426f03b30af739a7bbf34a038cd0 371 Gene3D G3DSA:2.30.30.60 196 246 3.6E-16 T 05-07-2017 K08M4_RS16850 1b87426f03b30af739a7bbf34a038cd0 371 Pfam PF00924 Mechanosensitive ion channel 138 341 2.4E-54 T 05-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 K08M4_RS16850 1b87426f03b30af739a7bbf34a038cd0 371 SUPERFAMILY SSF50182 180 247 5.56E-18 T 05-07-2017 IPR010920 LSM domain K08M4_RS16850 1b87426f03b30af739a7bbf34a038cd0 371 Gene3D G3DSA:3.30.70.100 252 339 7.5E-11 T 05-07-2017 K08M4_RS16850 1b87426f03b30af739a7bbf34a038cd0 371 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 212 246 - T 05-07-2017 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 K08M4_RS16850 1b87426f03b30af739a7bbf34a038cd0 371 SUPERFAMILY SSF82689 252 351 1.83E-16 T 05-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 K08M4_RS08355 a9438b2a51cc36d817db2009aa6878c9 415 Gene3D G3DSA:3.40.190.10 130 349 2.1E-30 T 05-07-2017 K08M4_RS08355 a9438b2a51cc36d817db2009aa6878c9 415 Pfam PF01547 Bacterial extracellular solute-binding protein 40 329 3.0E-25 T 05-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 K08M4_RS08355 a9438b2a51cc36d817db2009aa6878c9 415 SUPERFAMILY SSF53850 19 413 1.14E-48 T 05-07-2017 K08M4_RS02995 e7947c198cfdce702f2bf972fadf469c 328 SUPERFAMILY SSF161098 94 324 1.96E-14 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS02995 e7947c198cfdce702f2bf972fadf469c 328 Gene3D G3DSA:1.10.3720.10 95 320 1.1E-15 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS02995 e7947c198cfdce702f2bf972fadf469c 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 325 1.0E-40 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS03300 0b6cd5c394dbd6581bc1dad3d45bdcc0 71 Gene3D G3DSA:1.10.720.30 12 69 9.2E-33 T 05-07-2017 IPR003034 SAP domain K08M4_RS03300 0b6cd5c394dbd6581bc1dad3d45bdcc0 71 Pfam PF09905 Uncharacterized conserved protein (DUF2132) 5 66 3.2E-36 T 05-07-2017 IPR018668 DNA-binding protein VF530-like, bacteria GO:0003677 K08M4_RS02385 6c1153c10735cf97a76371565b01d244 392 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 295 308 - T 05-07-2017 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 K08M4_RS02385 6c1153c10735cf97a76371565b01d244 392 Gene3D G3DSA:3.50.50.60 3 183 5.4E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02385 6c1153c10735cf97a76371565b01d244 392 Gene3D G3DSA:3.50.50.60 269 354 5.4E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02385 6c1153c10735cf97a76371565b01d244 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 3.4E-10 T 05-07-2017 K08M4_RS02385 6c1153c10735cf97a76371565b01d244 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 3.4E-10 T 05-07-2017 K08M4_RS02385 6c1153c10735cf97a76371565b01d244 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 3.4E-10 T 05-07-2017 K08M4_RS02385 6c1153c10735cf97a76371565b01d244 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 3.4E-10 T 05-07-2017 K08M4_RS02385 6c1153c10735cf97a76371565b01d244 392 Pfam PF01494 FAD binding domain 4 337 3.6E-23 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 K08M4_RS02385 6c1153c10735cf97a76371565b01d244 392 TIGRFAM TIGR01984 UbiH: 2-polyprenyl-6-methoxyphenol 4-hydroxylase 5 388 2.5E-150 T 05-07-2017 IPR011295 2-polyprenyl-6-methoxyphenol 4-hydroxylase GO:0006744|GO:0008681 K08M4_RS02385 6c1153c10735cf97a76371565b01d244 392 SUPERFAMILY SSF51905 268 382 1.24E-47 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02385 6c1153c10735cf97a76371565b01d244 392 SUPERFAMILY SSF51905 3 178 1.24E-47 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS02385 6c1153c10735cf97a76371565b01d244 392 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 5 388 2.7E-124 T 05-07-2017 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 K08M4_RS06215 970a89fe7cde40095775fcb77492e28f 455 Pfam PF01554 MatE 19 178 1.2E-23 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS06215 970a89fe7cde40095775fcb77492e28f 455 Pfam PF01554 MatE 245 405 1.0E-7 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS13755 aeac19b8383fbba092c8fd7e9f567247 626 Pfam PF13727 CoA-binding domain 69 177 7.8E-6 T 05-07-2017 K08M4_RS13755 aeac19b8383fbba092c8fd7e9f567247 626 SUPERFAMILY SSF51735 281 557 8.81E-52 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13755 aeac19b8383fbba092c8fd7e9f567247 626 SUPERFAMILY SSF53335 110 330 1.08E-15 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS13755 aeac19b8383fbba092c8fd7e9f567247 626 Gene3D G3DSA:3.40.50.720 140 228 5.0E-10 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13755 aeac19b8383fbba092c8fd7e9f567247 626 Gene3D G3DSA:3.40.50.720 282 468 1.6E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13755 aeac19b8383fbba092c8fd7e9f567247 626 Pfam PF02719 Polysaccharide biosynthesis protein 284 578 4.8E-127 T 05-07-2017 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain K08M4_RS13755 aeac19b8383fbba092c8fd7e9f567247 626 Gene3D G3DSA:3.90.25.10 469 554 7.0E-8 T 05-07-2017 K08M4_RS05655 4b22072add1e93a40c0b93dfec90bb33 417 SUPERFAMILY SSF51905 1 54 3.24E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS05655 4b22072add1e93a40c0b93dfec90bb33 417 SUPERFAMILY SSF51905 360 416 3.24E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS05655 4b22072add1e93a40c0b93dfec90bb33 417 SUPERFAMILY SSF51905 107 270 3.24E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS05655 4b22072add1e93a40c0b93dfec90bb33 417 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 411 46.957 T 05-07-2017 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 K08M4_RS05655 4b22072add1e93a40c0b93dfec90bb33 417 SUPERFAMILY SSF54373 270 360 2.22E-17 T 05-07-2017 K08M4_RS05655 4b22072add1e93a40c0b93dfec90bb33 417 Gene3D G3DSA:3.30.9.10 134 189 2.0E-14 T 05-07-2017 K08M4_RS05655 4b22072add1e93a40c0b93dfec90bb33 417 Gene3D G3DSA:3.30.9.10 270 359 2.0E-14 T 05-07-2017 K08M4_RS05655 4b22072add1e93a40c0b93dfec90bb33 417 Gene3D G3DSA:3.50.50.60 2 55 2.3E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS05655 4b22072add1e93a40c0b93dfec90bb33 417 Gene3D G3DSA:3.50.50.60 360 416 2.3E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS05655 4b22072add1e93a40c0b93dfec90bb33 417 Gene3D G3DSA:3.50.50.60 190 269 2.3E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS05655 4b22072add1e93a40c0b93dfec90bb33 417 Gene3D G3DSA:3.50.50.60 108 122 2.3E-49 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS05655 4b22072add1e93a40c0b93dfec90bb33 417 Pfam PF01266 FAD dependent oxidoreductase 3 397 2.7E-69 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 K08M4_RS15875 24877c9d1a6190df5cd5db86be60e8e0 817 Pfam PF00343 Carbohydrate phosphorylase 99 812 0.0 T 05-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 K08M4_RS15875 24877c9d1a6190df5cd5db86be60e8e0 817 PIRSF PIRSF000460 1 817 2.5E-210 T 05-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 K08M4_RS15875 24877c9d1a6190df5cd5db86be60e8e0 817 SUPERFAMILY SSF53756 8 816 0.0 T 05-07-2017 K08M4_RS15875 24877c9d1a6190df5cd5db86be60e8e0 817 Gene3D G3DSA:3.40.50.2000 8 481 4.9E-196 T 05-07-2017 K08M4_RS15875 24877c9d1a6190df5cd5db86be60e8e0 817 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 11 812 0.0 T 05-07-2017 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 K08M4_RS15875 24877c9d1a6190df5cd5db86be60e8e0 817 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 656 668 - T 05-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 K08M4_RS15875 24877c9d1a6190df5cd5db86be60e8e0 817 Gene3D G3DSA:3.40.50.2000 482 796 1.1E-128 T 05-07-2017 K08M4_RS02220 ad03dff23199a3fc557563e5b3e35086 321 Pfam PF03186 CobD/Cbib protein 20 299 7.4E-88 T 05-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 K08M4_RS02220 ad03dff23199a3fc557563e5b3e35086 321 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 19 308 6.9E-58 T 05-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 K08M4_RS02220 ad03dff23199a3fc557563e5b3e35086 321 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 321 87.608 T 05-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 K08M4_RS06090 9f5958e3515de0f923c4a92056475556 345 Gene3D G3DSA:1.10.260.40 1 54 4.0E-5 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS06090 9f5958e3515de0f923c4a92056475556 345 Pfam PF06114 Domain of unknown function (DUF955) 132 243 1.1E-17 T 05-07-2017 IPR010359 HTH domain, IrrE-type K08M4_RS18570 0cb89afd18032837157b3dd4381ab110 187 SUPERFAMILY SSF110997 96 160 4.97E-6 T 05-07-2017 IPR007730 Sporulation-related domain GO:0042834 K08M4_RS18570 0cb89afd18032837157b3dd4381ab110 187 Pfam PF05036 Sporulation related domain 97 169 5.3E-11 T 05-07-2017 IPR007730 Sporulation-related domain GO:0042834 K08M4_RS18570 0cb89afd18032837157b3dd4381ab110 187 Gene3D G3DSA:3.30.70.1070 94 168 2.2E-4 T 05-07-2017 IPR007730 Sporulation-related domain GO:0042834 K08M4_RS20180 b258fa89069ba8180798ec8a9ecbc419 254 SUPERFAMILY SSF52540 2 227 3.07E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20180 b258fa89069ba8180798ec8a9ecbc419 254 Gene3D G3DSA:3.40.50.300 1 236 3.3E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20180 b258fa89069ba8180798ec8a9ecbc419 254 Pfam PF00005 ABC transporter 19 165 6.2E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS20180 b258fa89069ba8180798ec8a9ecbc419 254 SMART SM00382 26 214 3.9E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS20180 b258fa89069ba8180798ec8a9ecbc419 254 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS02895 9abe3369f67d34204a67e1f5b40caea1 148 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 25 147 30.0 T 05-07-2017 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 K08M4_RS02895 9abe3369f67d34204a67e1f5b40caea1 148 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 29 137 3.9E-51 T 05-07-2017 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 K08M4_RS02895 9abe3369f67d34204a67e1f5b40caea1 148 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 108 140 5.8E-10 T 05-07-2017 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 K08M4_RS02895 9abe3369f67d34204a67e1f5b40caea1 148 SUPERFAMILY SSF109635 7 107 9.94E-37 T 05-07-2017 K08M4_RS02895 9abe3369f67d34204a67e1f5b40caea1 148 SUPERFAMILY SSF57716 108 146 1.57E-9 T 05-07-2017 K08M4_RS02895 9abe3369f67d34204a67e1f5b40caea1 148 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 111 135 - T 05-07-2017 IPR020458 Zinc finger, DksA/TraR C4-type conserved site K08M4_RS02140 98c1a88b7b9654e5aba95abff3f2cd5d 96 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 8 91 1.1E-26 T 05-07-2017 IPR005228 Conserved hypothetical protein CHP00251 K08M4_RS02140 98c1a88b7b9654e5aba95abff3f2cd5d 96 Hamap MF_00634 UPF0235 protein YggU [yggU]. 8 96 20.578 T 05-07-2017 IPR003746 Protein of unknown function DUF167 K08M4_RS02140 98c1a88b7b9654e5aba95abff3f2cd5d 96 Gene3D G3DSA:3.30.1200.10 2 92 3.2E-30 T 05-07-2017 IPR003746 Protein of unknown function DUF167 K08M4_RS02140 98c1a88b7b9654e5aba95abff3f2cd5d 96 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 12 82 4.8E-26 T 05-07-2017 IPR003746 Protein of unknown function DUF167 K08M4_RS02140 98c1a88b7b9654e5aba95abff3f2cd5d 96 SUPERFAMILY SSF69786 4 96 1.83E-32 T 05-07-2017 IPR003746 Protein of unknown function DUF167 K08M4_RS02140 98c1a88b7b9654e5aba95abff3f2cd5d 96 SMART SM01152 8 84 2.4E-38 T 05-07-2017 IPR003746 Protein of unknown function DUF167 K08M4_RS05390 5a1ad864521d8e2a8c7d3b927e65a2b3 151 Pfam PF05433 Glycine zipper 2TM domain 56 93 9.9E-9 T 05-07-2017 IPR008816 Glycine zipper 2TM domain GO:0019867 K08M4_RS21585 f9a25239c285e42f8a475af61062df22 268 Pfam PF07103 Protein of unknown function (DUF1365) 23 265 1.2E-68 T 05-07-2017 IPR010775 Protein of unknown function DUF1365 K08M4_RS06950 5fe2824494d9fa19d3002e055339fe9b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 5.5E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS06950 5fe2824494d9fa19d3002e055339fe9b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.5E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS06950 5fe2824494d9fa19d3002e055339fe9b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 5.5E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS06950 5fe2824494d9fa19d3002e055339fe9b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 5.5E-10 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS06950 5fe2824494d9fa19d3002e055339fe9b 246 SUPERFAMILY SSF51735 8 246 9.63E-46 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS06950 5fe2824494d9fa19d3002e055339fe9b 246 Gene3D G3DSA:3.40.50.720 9 246 3.3E-49 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS06950 5fe2824494d9fa19d3002e055339fe9b 246 Pfam PF00106 short chain dehydrogenase 8 203 3.1E-21 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS07565 9eda9e5aed00296c8cb5c59b86df2f26 244 Pfam PF02146 Sir2 family 13 186 2.5E-49 T 05-07-2017 IPR003000 Sirtuin family GO:0070403 K08M4_RS07565 9eda9e5aed00296c8cb5c59b86df2f26 244 Gene3D G3DSA:3.30.1600.10 22 61 3.2E-27 T 05-07-2017 IPR026591 Sirtuin family, catalytic core small domain K08M4_RS07565 9eda9e5aed00296c8cb5c59b86df2f26 244 Gene3D G3DSA:3.30.1600.10 114 158 3.2E-27 T 05-07-2017 IPR026591 Sirtuin family, catalytic core small domain K08M4_RS07565 9eda9e5aed00296c8cb5c59b86df2f26 244 Gene3D G3DSA:3.40.50.1220 71 113 1.9E-41 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain K08M4_RS07565 9eda9e5aed00296c8cb5c59b86df2f26 244 Gene3D G3DSA:3.40.50.1220 165 230 1.9E-41 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain K08M4_RS07565 9eda9e5aed00296c8cb5c59b86df2f26 244 Gene3D G3DSA:3.40.50.1220 6 21 1.9E-41 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain K08M4_RS07565 9eda9e5aed00296c8cb5c59b86df2f26 244 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 6 236 54.973 T 05-07-2017 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 K08M4_RS07565 9eda9e5aed00296c8cb5c59b86df2f26 244 SUPERFAMILY SSF52467 6 235 3.66E-72 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain K08M4_RS01185 e8c2bc80799947648e8898c436c40168 179 Pfam PF10400 Virulence activator alpha C-term 92 175 2.8E-13 T 05-07-2017 IPR018309 Transcription regulator PadR, C-terminal K08M4_RS01185 e8c2bc80799947648e8898c436c40168 179 Gene3D G3DSA:1.10.10.10 1 87 4.4E-28 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS01185 e8c2bc80799947648e8898c436c40168 179 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 2.9E-14 T 05-07-2017 IPR005149 Transcription regulator PadR, N-terminal K08M4_RS01185 e8c2bc80799947648e8898c436c40168 179 SUPERFAMILY SSF46785 3 176 3.91E-42 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS00535 865f610c650615e452522a33271d0945 78 TIGRFAM TIGR03853 matur_matur: putative metal-binding protein 4 78 1.3E-27 T 05-07-2017 IPR019620 Putative metal-binding protein K08M4_RS00535 865f610c650615e452522a33271d0945 78 Pfam PF10678 Protein of unknown function (DUF2492) 4 77 3.1E-26 T 05-07-2017 IPR019620 Putative metal-binding protein K08M4_RS17430 8bdc9550df9d76b31e1c4f369624bd29 211 Gene3D G3DSA:2.160.10.10 62 205 7.7E-49 T 05-07-2017 K08M4_RS17430 8bdc9550df9d76b31e1c4f369624bd29 211 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 144 6.5E-11 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS17430 8bdc9550df9d76b31e1c4f369624bd29 211 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 118 146 - T 05-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 K08M4_RS17430 8bdc9550df9d76b31e1c4f369624bd29 211 SUPERFAMILY SSF51161 36 203 2.77E-45 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS17405 c75d9880cec265c0a0b02863c22f720e 664 SUPERFAMILY SSF81345 356 660 5.89E-61 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS17405 c75d9880cec265c0a0b02863c22f720e 664 Gene3D G3DSA:1.10.3470.10 386 663 2.6E-70 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS17405 c75d9880cec265c0a0b02863c22f720e 664 Gene3D G3DSA:1.10.3470.10 6 333 7.4E-64 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS17405 c75d9880cec265c0a0b02863c22f720e 664 Pfam PF01032 FecCD transport family 40 332 1.1E-61 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 K08M4_RS17405 c75d9880cec265c0a0b02863c22f720e 664 Pfam PF01032 FecCD transport family 363 660 1.2E-67 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 K08M4_RS17405 c75d9880cec265c0a0b02863c22f720e 664 SUPERFAMILY SSF81345 8 332 4.45E-55 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS00490 6768d46099d8b6064026d0d90278d2fc 113 Gene3D G3DSA:1.10.10.10 5 87 7.6E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS00490 6768d46099d8b6064026d0d90278d2fc 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 9.4E-16 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS00490 6768d46099d8b6064026d0d90278d2fc 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 9.4E-16 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS00490 6768d46099d8b6064026d0d90278d2fc 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 9.4E-16 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS00490 6768d46099d8b6064026d0d90278d2fc 113 Pfam PF01022 Bacterial regulatory protein, arsR family 12 58 7.9E-11 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS00490 6768d46099d8b6064026d0d90278d2fc 113 SMART SM00418 5 83 1.5E-23 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS00490 6768d46099d8b6064026d0d90278d2fc 113 SUPERFAMILY SSF46785 5 88 2.02E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS18730 7ed7fcb04667a57db5613bafc21ca72b 285 Pfam PF08543 Phosphomethylpyrimidine kinase 82 256 3.3E-21 T 05-07-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 K08M4_RS18730 7ed7fcb04667a57db5613bafc21ca72b 285 Gene3D G3DSA:3.40.1190.20 1 281 5.3E-85 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS18730 7ed7fcb04667a57db5613bafc21ca72b 285 SUPERFAMILY SSF53613 1 272 1.87E-70 T 05-07-2017 IPR029056 Ribokinase-like K08M4_RS18730 7ed7fcb04667a57db5613bafc21ca72b 285 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 1 283 1.8E-100 T 05-07-2017 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 K08M4_RS13675 bf92039da0e4adfee1d648dbbc2ac010 254 SUPERFAMILY SSF46548 107 226 2.79E-30 T 05-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 K08M4_RS13675 bf92039da0e4adfee1d648dbbc2ac010 254 SUPERFAMILY SSF54292 5 106 4.33E-30 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 K08M4_RS13675 bf92039da0e4adfee1d648dbbc2ac010 254 Gene3D G3DSA:1.10.1060.10 107 230 5.9E-35 T 05-07-2017 K08M4_RS13675 bf92039da0e4adfee1d648dbbc2ac010 254 Gene3D G3DSA:3.10.20.30 3 106 5.2E-35 T 05-07-2017 IPR012675 Beta-grasp domain K08M4_RS13675 bf92039da0e4adfee1d648dbbc2ac010 254 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS13675 bf92039da0e4adfee1d648dbbc2ac010 254 Pfam PF13183 4Fe-4S dicluster domain 147 219 1.8E-10 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain K08M4_RS13675 bf92039da0e4adfee1d648dbbc2ac010 254 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 05-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 K08M4_RS13675 bf92039da0e4adfee1d648dbbc2ac010 254 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 111 4.2E-34 T 05-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS13675 bf92039da0e4adfee1d648dbbc2ac010 254 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 229 6.6E-93 T 05-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS15725 7e3e74846b8e24bdd4e7d7939df3d7db 314 Pfam PF01553 Acyltransferase 72 226 1.4E-15 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 K08M4_RS15725 7e3e74846b8e24bdd4e7d7939df3d7db 314 Gene3D G3DSA:3.40.1130.10 76 193 6.5E-4 T 05-07-2017 K08M4_RS15725 7e3e74846b8e24bdd4e7d7939df3d7db 314 SUPERFAMILY SSF69593 15 284 2.22E-34 T 05-07-2017 K08M4_RS15725 7e3e74846b8e24bdd4e7d7939df3d7db 314 SMART SM00563 85 223 2.2E-16 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 K08M4_RS15595 1208766aca033a1c7aab1d4f269da22a 194 Gene3D G3DSA:1.10.357.10 3 166 4.3E-31 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS15595 1208766aca033a1c7aab1d4f269da22a 194 SUPERFAMILY SSF48498 78 140 3.48E-6 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal K08M4_RS15595 1208766aca033a1c7aab1d4f269da22a 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 6.9E-15 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS15595 1208766aca033a1c7aab1d4f269da22a 194 SUPERFAMILY SSF46689 3 76 5.64E-16 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS15595 1208766aca033a1c7aab1d4f269da22a 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 1.2E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS15595 1208766aca033a1c7aab1d4f269da22a 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 1.2E-8 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS18605 76cdfb2b404d4364e9d687a041177642 316 SMART SM00797 31 313 1.1E-115 T 05-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B K08M4_RS18605 76cdfb2b404d4364e9d687a041177642 316 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 10 297 6.4E-78 T 05-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B K08M4_RS18605 76cdfb2b404d4364e9d687a041177642 316 SUPERFAMILY SSF50891 190 296 3.22E-7 T 05-07-2017 IPR029000 Cyclophilin-like domain K08M4_RS18605 76cdfb2b404d4364e9d687a041177642 316 Pfam PF02626 Allophanate hydrolase subunit 2 32 296 2.0E-83 T 05-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B K08M4_RS18455 1433b4514bd8ac601e77499a013117a1 252 Gene3D G3DSA:3.40.190.10 1 96 2.2E-11 T 05-07-2017 K08M4_RS18455 1433b4514bd8ac601e77499a013117a1 252 SUPERFAMILY SSF53850 25 250 1.14E-58 T 05-07-2017 K08M4_RS18455 1433b4514bd8ac601e77499a013117a1 252 Gene3D G3DSA:3.40.190.10 105 215 2.2E-39 T 05-07-2017 K08M4_RS18455 1433b4514bd8ac601e77499a013117a1 252 PIRSF PIRSF004846 1 252 1.1E-63 T 05-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 K08M4_RS18455 1433b4514bd8ac601e77499a013117a1 252 Pfam PF13531 Bacterial extracellular solute-binding protein 27 250 5.6E-41 T 05-07-2017 K08M4_RS18455 1433b4514bd8ac601e77499a013117a1 252 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 32 248 9.4E-59 T 05-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 K08M4_RS21495 50e954ec4d64c4d8afe743769d677d30 266 SUPERFAMILY SSF100950 1 264 4.61E-103 T 05-07-2017 K08M4_RS21495 50e954ec4d64c4d8afe743769d677d30 266 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 224 4.6E-20 T 05-07-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 K08M4_RS21495 50e954ec4d64c4d8afe743769d677d30 266 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 247 40.881 T 05-07-2017 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 K08M4_RS21495 50e954ec4d64c4d8afe743769d677d30 266 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 259 5.0E-137 T 05-07-2017 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 K08M4_RS21495 50e954ec4d64c4d8afe743769d677d30 266 Gene3D G3DSA:3.40.50.1360 1 264 2.2E-109 T 05-07-2017 K08M4_RS21495 50e954ec4d64c4d8afe743769d677d30 266 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 125 143 - T 05-07-2017 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 K08M4_RS00905 f9fb2c0e01a8d28fb9aaa749b9a258ff 98 Pfam PF02954 Bacterial regulatory protein, Fis family 55 95 3.9E-14 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS00905 f9fb2c0e01a8d28fb9aaa749b9a258ff 98 Gene3D G3DSA:1.10.10.60 27 98 3.2E-27 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00905 f9fb2c0e01a8d28fb9aaa749b9a258ff 98 SUPERFAMILY SSF46689 8 98 1.84E-24 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00905 f9fb2c0e01a8d28fb9aaa749b9a258ff 98 PIRSF PIRSF002097 1 98 2.3E-44 T 05-07-2017 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 K08M4_RS00905 f9fb2c0e01a8d28fb9aaa749b9a258ff 98 PRINTS PR01591 DNA-binding protein FIS signature 57 69 2.0E-31 T 05-07-2017 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 K08M4_RS00905 f9fb2c0e01a8d28fb9aaa749b9a258ff 98 PRINTS PR01591 DNA-binding protein FIS signature 9 26 2.0E-31 T 05-07-2017 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 K08M4_RS00905 f9fb2c0e01a8d28fb9aaa749b9a258ff 98 PRINTS PR01591 DNA-binding protein FIS signature 26 42 2.0E-31 T 05-07-2017 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 K08M4_RS00905 f9fb2c0e01a8d28fb9aaa749b9a258ff 98 PRINTS PR01591 DNA-binding protein FIS signature 42 57 2.0E-31 T 05-07-2017 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 K08M4_RS00905 f9fb2c0e01a8d28fb9aaa749b9a258ff 98 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 61 78 3.3E-13 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS00905 f9fb2c0e01a8d28fb9aaa749b9a258ff 98 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 78 98 3.3E-13 T 05-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 K08M4_RS00905 f9fb2c0e01a8d28fb9aaa749b9a258ff 98 Hamap MF_00166 DNA-binding protein Fis [fis]. 1 98 31.5 T 05-07-2017 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 K08M4_RS21525 fb76d437fb9daff3793b991f02fd7373 408 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 11 407 2.5E-133 T 05-07-2017 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 K08M4_RS21525 fb76d437fb9daff3793b991f02fd7373 408 Pfam PF03616 Sodium/glutamate symporter 6 376 1.9E-150 T 05-07-2017 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 K08M4_RS05325 ba23843395df23b4cd595e63890f91e9 182 Pfam PF07445 Primosomal replication protein priC 5 173 9.5E-41 T 05-07-2017 IPR010890 Primosomal replication PriB/PriC K08M4_RS01180 a0656436bc0e5d5ac86deb761966ede4 299 Pfam PF02219 Methylenetetrahydrofolate reductase 17 291 1.5E-101 T 05-07-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 K08M4_RS01180 a0656436bc0e5d5ac86deb761966ede4 299 Gene3D G3DSA:3.20.20.220 16 295 8.3E-107 T 05-07-2017 IPR029041 FAD-linked oxidoreductase-like K08M4_RS01180 a0656436bc0e5d5ac86deb761966ede4 299 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 25 290 3.8E-103 T 05-07-2017 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 K08M4_RS01180 a0656436bc0e5d5ac86deb761966ede4 299 SUPERFAMILY SSF51730 22 294 1.71E-95 T 05-07-2017 IPR029041 FAD-linked oxidoreductase-like K08M4_RS02605 12f2f4221f1e61aa153b90d2a2794616 346 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 209 240 4.1E-7 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS02605 12f2f4221f1e61aa153b90d2a2794616 346 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 113 147 9.5E-10 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS02605 12f2f4221f1e61aa153b90d2a2794616 346 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 6 313 2.0E-73 T 05-07-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 K08M4_RS02605 12f2f4221f1e61aa153b90d2a2794616 346 SUPERFAMILY SSF51161 106 302 4.55E-56 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS02605 12f2f4221f1e61aa153b90d2a2794616 346 Gene3D G3DSA:2.160.10.10 196 294 6.0E-25 T 05-07-2017 K08M4_RS02605 12f2f4221f1e61aa153b90d2a2794616 346 Gene3D G3DSA:2.160.10.10 55 120 1.7E-5 T 05-07-2017 K08M4_RS02605 12f2f4221f1e61aa153b90d2a2794616 346 Gene3D G3DSA:2.160.10.10 121 195 2.2E-19 T 05-07-2017 K08M4_RS21520 894a2ff2d3b4b4ea884797f24abf7ba9 389 Gene3D G3DSA:3.50.50.60 108 300 1.2E-43 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS21520 894a2ff2d3b4b4ea884797f24abf7ba9 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 4.7E-22 T 05-07-2017 K08M4_RS21520 894a2ff2d3b4b4ea884797f24abf7ba9 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 4.7E-22 T 05-07-2017 K08M4_RS21520 894a2ff2d3b4b4ea884797f24abf7ba9 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 229 245 4.7E-22 T 05-07-2017 K08M4_RS21520 894a2ff2d3b4b4ea884797f24abf7ba9 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 4.7E-22 T 05-07-2017 K08M4_RS21520 894a2ff2d3b4b4ea884797f24abf7ba9 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 276 4.7E-22 T 05-07-2017 K08M4_RS21520 894a2ff2d3b4b4ea884797f24abf7ba9 389 SUPERFAMILY SSF51905 2 300 4.67E-38 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS21520 894a2ff2d3b4b4ea884797f24abf7ba9 389 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 282 2.1E-55 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS21520 894a2ff2d3b4b4ea884797f24abf7ba9 389 Gene3D G3DSA:3.50.50.60 2 107 1.5E-20 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS21520 894a2ff2d3b4b4ea884797f24abf7ba9 389 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.1E-16 T 05-07-2017 K08M4_RS21520 894a2ff2d3b4b4ea884797f24abf7ba9 389 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 230 244 4.1E-16 T 05-07-2017 K08M4_RS21520 894a2ff2d3b4b4ea884797f24abf7ba9 389 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 276 4.1E-16 T 05-07-2017 K08M4_RS21520 894a2ff2d3b4b4ea884797f24abf7ba9 389 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 169 4.1E-16 T 05-07-2017 K08M4_RS19475 e5f280f9f46a562de165d89a1acaac97 523 SMART SM00052 249 497 5.4E-77 T 05-07-2017 IPR001633 EAL domain K08M4_RS19475 e5f280f9f46a562de165d89a1acaac97 523 SUPERFAMILY SSF141868 256 504 4.05E-71 T 05-07-2017 IPR001633 EAL domain K08M4_RS19475 e5f280f9f46a562de165d89a1acaac97 523 Pfam PF12792 CSS motif domain associated with EAL 34 225 1.3E-29 T 05-07-2017 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain K08M4_RS19475 e5f280f9f46a562de165d89a1acaac97 523 Gene3D G3DSA:3.20.20.450 253 504 1.6E-74 T 05-07-2017 IPR001633 EAL domain K08M4_RS19475 e5f280f9f46a562de165d89a1acaac97 523 Pfam PF00563 EAL domain 257 492 2.4E-62 T 05-07-2017 IPR001633 EAL domain K08M4_RS07020 b146eeb8549b5ca4cc5b234efb43db2b 133 Gene3D G3DSA:3.90.79.10 9 111 2.1E-20 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS07020 b146eeb8549b5ca4cc5b234efb43db2b 133 Pfam PF00293 NUDIX domain 11 108 4.1E-12 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 K08M4_RS07020 b146eeb8549b5ca4cc5b234efb43db2b 133 SUPERFAMILY SSF55811 9 112 2.17E-19 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS15280 00464aaa690c818d4ad5b43dfe6a2e0a 142 Pfam PF01814 Hemerythrin HHE cation binding domain 4 120 1.7E-12 T 05-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 K08M4_RS15280 00464aaa690c818d4ad5b43dfe6a2e0a 142 Gene3D G3DSA:1.20.120.520 26 139 1.4E-9 T 05-07-2017 K08M4_RS01190 f76850031c20417ce570345628efb1c9 876 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 1 876 17.691 T 05-07-2017 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 K08M4_RS01190 f76850031c20417ce570345628efb1c9 876 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 134 145 - T 05-07-2017 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 K08M4_RS01190 f76850031c20417ce570345628efb1c9 876 Pfam PF00311 Phosphoenolpyruvate carboxylase 129 876 9.2E-285 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 K08M4_RS01190 f76850031c20417ce570345628efb1c9 876 SUPERFAMILY SSF51621 6 876 0.0 T 05-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 K08M4_RS01190 f76850031c20417ce570345628efb1c9 876 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 186 202 2.6E-67 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 K08M4_RS01190 f76850031c20417ce570345628efb1c9 876 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 245 260 2.6E-67 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 K08M4_RS01190 f76850031c20417ce570345628efb1c9 876 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 383 403 2.6E-67 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 K08M4_RS01190 f76850031c20417ce570345628efb1c9 876 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 133 146 2.6E-67 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 K08M4_RS01190 f76850031c20417ce570345628efb1c9 876 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 532 552 2.6E-67 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 K08M4_RS01190 f76850031c20417ce570345628efb1c9 876 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 574 603 2.6E-67 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 K08M4_RS01190 f76850031c20417ce570345628efb1c9 876 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 706 732 2.6E-67 T 05-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 K08M4_RS01190 f76850031c20417ce570345628efb1c9 876 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 534 546 - T 05-07-2017 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 K08M4_RS01190 f76850031c20417ce570345628efb1c9 876 Gene3D G3DSA:1.20.1440.90 273 386 7.9E-30 T 05-07-2017 K08M4_RS04590 fc41291b49f32bf7d3ff62e47d01027f 367 Pfam PF00072 Response regulator receiver domain 22 123 5.3E-27 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS04590 fc41291b49f32bf7d3ff62e47d01027f 367 SUPERFAMILY SSF52172 19 136 2.7E-33 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS04590 fc41291b49f32bf7d3ff62e47d01027f 367 SMART SM00448 20 132 1.1E-30 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS04590 fc41291b49f32bf7d3ff62e47d01027f 367 Gene3D G3DSA:3.40.50.2300 19 136 4.4E-33 T 05-07-2017 K08M4_RS10750 36ed874e2fc6fd32ee4df31997e88e99 284 Gene3D G3DSA:1.25.40.10 111 196 4.2E-28 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS10750 36ed874e2fc6fd32ee4df31997e88e99 284 SUPERFAMILY SSF52833 3 111 2.47E-27 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS10750 36ed874e2fc6fd32ee4df31997e88e99 284 Pfam PF14559 Tetratricopeptide repeat 125 190 1.5E-11 T 05-07-2017 K08M4_RS10750 36ed874e2fc6fd32ee4df31997e88e99 284 Pfam PF00085 Thioredoxin 6 109 5.8E-16 T 05-07-2017 IPR013766 Thioredoxin domain GO:0045454 K08M4_RS10750 36ed874e2fc6fd32ee4df31997e88e99 284 SUPERFAMILY SSF48452 108 245 1.65E-8 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS10750 36ed874e2fc6fd32ee4df31997e88e99 284 Gene3D G3DSA:3.40.30.10 3 110 2.7E-23 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS10750 36ed874e2fc6fd32ee4df31997e88e99 284 Pfam PF14561 Tetratricopeptide repeat 195 284 1.6E-29 T 05-07-2017 K08M4_RS10750 36ed874e2fc6fd32ee4df31997e88e99 284 Gene3D G3DSA:1.25.40.10 197 284 1.7E-31 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS07340 0743e9b0cdd73de10dc83abbd9a17f38 261 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 125 159 0.073 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS07340 0743e9b0cdd73de10dc83abbd9a17f38 261 SUPERFAMILY SSF51161 96 239 4.16E-32 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS07340 0743e9b0cdd73de10dc83abbd9a17f38 261 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 194 222 - T 05-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 K08M4_RS07340 0743e9b0cdd73de10dc83abbd9a17f38 261 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 186 220 6.9E-8 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS07340 0743e9b0cdd73de10dc83abbd9a17f38 261 Gene3D G3DSA:2.160.10.10 75 243 3.1E-38 T 05-07-2017 K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 PRINTS PR00313 NodO calcium binding signature 4930 4939 2.8E-6 T 05-07-2017 K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 PRINTS PR00313 NodO calcium binding signature 4912 4920 2.8E-6 T 05-07-2017 K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 PRINTS PR00313 NodO calcium binding signature 4900 4911 2.8E-6 T 05-07-2017 K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 PRINTS PR00313 NodO calcium binding signature 4921 4929 2.8E-6 T 05-07-2017 K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 4899 4917 - T 05-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 4917 4935 - T 05-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 TIGRFAM TIGR03660 T1SS_rpt_143: T1SS-143 repeat domain 1057 1189 6.4E-22 T 05-07-2017 IPR019959 T1SS-143 repeat-containing domain K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 TIGRFAM TIGR03660 T1SS_rpt_143: T1SS-143 repeat domain 1607 1739 1.0E-21 T 05-07-2017 IPR019959 T1SS-143 repeat-containing domain K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 TIGRFAM TIGR03660 T1SS_rpt_143: T1SS-143 repeat domain 2154 2296 1.5E-21 T 05-07-2017 IPR019959 T1SS-143 repeat-containing domain K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 TIGRFAM TIGR03660 T1SS_rpt_143: T1SS-143 repeat domain 1882 2016 5.8E-21 T 05-07-2017 IPR019959 T1SS-143 repeat-containing domain K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 TIGRFAM TIGR03660 T1SS_rpt_143: T1SS-143 repeat domain 782 922 9.6E-23 T 05-07-2017 IPR019959 T1SS-143 repeat-containing domain K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 TIGRFAM TIGR03660 T1SS_rpt_143: T1SS-143 repeat domain 2448 2580 3.5E-31 T 05-07-2017 IPR019959 T1SS-143 repeat-containing domain K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 TIGRFAM TIGR03660 T1SS_rpt_143: T1SS-143 repeat domain 2302 2444 2.0E-35 T 05-07-2017 IPR019959 T1SS-143 repeat-containing domain K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 TIGRFAM TIGR03660 T1SS_rpt_143: T1SS-143 repeat domain 1332 1464 2.5E-22 T 05-07-2017 IPR019959 T1SS-143 repeat-containing domain K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 4948 5038 9.5E-9 T 05-07-2017 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 4908 4926 - T 05-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site K08M4_RS06170 27dfbced36adfb9485e251412d856f2a 5041 SUPERFAMILY SSF51120 4855 4967 8.89E-21 T 05-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal K08M4_RS05210 0a6bed9c684ee7eb5bf4e3be55079c22 489 Pfam PF00817 impB/mucB/samB family 14 150 8.8E-8 T 05-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 K08M4_RS05210 0a6bed9c684ee7eb5bf4e3be55079c22 489 SUPERFAMILY SSF56672 11 232 1.85E-28 T 05-07-2017 K08M4_RS01840 5294bf31e37b4522dc675b91b4b18f80 321 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 2 311 2.7E-81 T 05-07-2017 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 K08M4_RS01840 5294bf31e37b4522dc675b91b4b18f80 321 Pfam PF01699 Sodium/calcium exchanger protein 5 143 1.2E-27 T 05-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 K08M4_RS01840 5294bf31e37b4522dc675b91b4b18f80 321 Pfam PF01699 Sodium/calcium exchanger protein 175 315 3.2E-26 T 05-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 K08M4_RS13525 4320899480a13b75a7d988dff4ff1f1e 88 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 7.0E-30 T 05-07-2017 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 K08M4_RS13525 4320899480a13b75a7d988dff4ff1f1e 88 Gene3D G3DSA:2.30.30.100 1 75 4.0E-38 T 05-07-2017 K08M4_RS13525 4320899480a13b75a7d988dff4ff1f1e 88 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 3 64 27.727 T 05-07-2017 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 K08M4_RS13525 4320899480a13b75a7d988dff4ff1f1e 88 SUPERFAMILY SSF50182 7 69 1.62E-24 T 05-07-2017 IPR010920 LSM domain K08M4_RS17280 0071a37c90d215878455737c50b08e33 376 Gene3D G3DSA:1.25.40.10 31 228 7.9E-16 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS17280 0071a37c90d215878455737c50b08e33 376 SUPERFAMILY SSF48452 58 213 6.92E-12 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS17280 0071a37c90d215878455737c50b08e33 376 Pfam PF13432 Tetratricopeptide repeat 92 152 1.3E-6 T 05-07-2017 K08M4_RS00305 821e2dcaffbd2696a3bcee828c77421d 89 Gene3D G3DSA:3.10.20.30 2 86 1.0E-23 T 05-07-2017 IPR012675 Beta-grasp domain K08M4_RS00305 821e2dcaffbd2696a3bcee828c77421d 89 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 79 1.8E-14 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 K08M4_RS00305 821e2dcaffbd2696a3bcee828c77421d 89 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 05-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 K08M4_RS00305 821e2dcaffbd2696a3bcee828c77421d 89 SUPERFAMILY SSF54292 1 87 3.67E-26 T 05-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 K08M4_RS03975 7cf6d6484d452a124aceabc5c31921b4 261 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 21 253 4.3E-76 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal K08M4_RS03975 7cf6d6484d452a124aceabc5c31921b4 261 SUPERFAMILY SSF53901 22 159 2.2E-8 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS08665 3df2f0e3954c2021299a3dd2ae1e1370 560 Pfam PF02080 TrkA-C domain 309 374 3.0E-8 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS08665 3df2f0e3954c2021299a3dd2ae1e1370 560 Pfam PF02080 TrkA-C domain 232 281 2.1E-8 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS08665 3df2f0e3954c2021299a3dd2ae1e1370 560 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 393 544 1.2E-37 T 05-07-2017 IPR006512 YidE/YbjL duplication K08M4_RS08665 3df2f0e3954c2021299a3dd2ae1e1370 560 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 21 171 9.4E-28 T 05-07-2017 IPR006512 YidE/YbjL duplication K08M4_RS08665 3df2f0e3954c2021299a3dd2ae1e1370 560 Gene3D G3DSA:3.30.70.1450 308 377 8.3E-7 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS08665 3df2f0e3954c2021299a3dd2ae1e1370 560 SUPERFAMILY SSF116726 231 285 2.88E-10 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS08665 3df2f0e3954c2021299a3dd2ae1e1370 560 Hamap MF_01015 Putative transport protein YbjL [ybjL]. 1 560 57.552 T 05-07-2017 IPR023017 Transport protein YbjL, putative K08M4_RS08665 3df2f0e3954c2021299a3dd2ae1e1370 560 Gene3D G3DSA:3.30.70.1450 232 286 5.2E-8 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS08665 3df2f0e3954c2021299a3dd2ae1e1370 560 Pfam PF06826 Predicted Permease Membrane Region 17 185 4.9E-35 T 05-07-2017 IPR006512 YidE/YbjL duplication K08M4_RS08665 3df2f0e3954c2021299a3dd2ae1e1370 560 Pfam PF06826 Predicted Permease Membrane Region 389 557 1.8E-41 T 05-07-2017 IPR006512 YidE/YbjL duplication K08M4_RS08665 3df2f0e3954c2021299a3dd2ae1e1370 560 SUPERFAMILY SSF116726 294 377 6.93E-10 T 05-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 K08M4_RS12010 7b0718ef2fdb65235e7d169bd64c6978 569 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 285 560 1.9E-76 T 05-07-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 K08M4_RS12010 7b0718ef2fdb65235e7d169bd64c6978 569 Gene3D G3DSA:1.10.3720.10 295 564 1.2E-48 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS12010 7b0718ef2fdb65235e7d169bd64c6978 569 Gene3D G3DSA:1.10.3720.10 32 49 1.2E-48 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS12010 7b0718ef2fdb65235e7d169bd64c6978 569 SUPERFAMILY SSF161098 295 550 2.49E-36 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS12010 7b0718ef2fdb65235e7d169bd64c6978 569 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 336 487 4.9E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS06155 94a6272ac206ba0420293ba815b31c1e 478 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 223 230 - T 05-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 K08M4_RS06155 94a6272ac206ba0420293ba815b31c1e 478 Gene3D G3DSA:3.40.309.10 239 428 2.2E-54 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 K08M4_RS06155 94a6272ac206ba0420293ba815b31c1e 478 SUPERFAMILY SSF53720 12 449 5.11E-117 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 K08M4_RS06155 94a6272ac206ba0420293ba815b31c1e 478 Pfam PF00171 Aldehyde dehydrogenase family 13 448 9.6E-93 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS06155 94a6272ac206ba0420293ba815b31c1e 478 PIRSF PIRSF036492 5 478 3.4E-166 T 05-07-2017 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 K08M4_RS06155 94a6272ac206ba0420293ba815b31c1e 478 Gene3D G3DSA:3.40.605.10 14 238 1.2E-56 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS11365 d74745d3d150578dbb2e03e231423a9e 314 TIGRFAM TIGR02405 trehalos_R_Ecol: trehalose operon repressor 4 310 2.1E-133 T 05-07-2017 IPR012771 Trehalose operon repressor GO:0003677|GO:0005991|GO:0045892 K08M4_RS11365 d74745d3d150578dbb2e03e231423a9e 314 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 05-07-2017 K08M4_RS11365 d74745d3d150578dbb2e03e231423a9e 314 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 5.5E-19 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS11365 d74745d3d150578dbb2e03e231423a9e 314 Gene3D G3DSA:1.10.260.40 6 56 5.4E-23 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS11365 d74745d3d150578dbb2e03e231423a9e 314 Gene3D G3DSA:3.40.50.2300 57 174 2.3E-25 T 05-07-2017 K08M4_RS11365 d74745d3d150578dbb2e03e231423a9e 314 Gene3D G3DSA:3.40.50.2300 175 278 3.4E-35 T 05-07-2017 K08M4_RS11365 d74745d3d150578dbb2e03e231423a9e 314 SMART SM00354 4 74 2.9E-31 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS11365 d74745d3d150578dbb2e03e231423a9e 314 SUPERFAMILY SSF53822 63 305 8.05E-57 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS11365 d74745d3d150578dbb2e03e231423a9e 314 Pfam PF13377 Periplasmic binding protein-like domain 168 310 2.3E-18 T 05-07-2017 K08M4_RS11365 d74745d3d150578dbb2e03e231423a9e 314 SUPERFAMILY SSF47413 3 60 7.74E-16 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS00505 208d2252139435a7bb315631aef30757 406 Gene3D G3DSA:1.20.1250.20 217 402 7.3E-9 T 05-07-2017 K08M4_RS00505 208d2252139435a7bb315631aef30757 406 SUPERFAMILY SSF103473 9 400 1.96E-31 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS00505 208d2252139435a7bb315631aef30757 406 Pfam PF07690 Major Facilitator Superfamily 17 339 2.2E-18 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS00505 208d2252139435a7bb315631aef30757 406 Gene3D G3DSA:1.20.1250.20 10 200 1.0E-14 T 05-07-2017 K08M4_RS15965 3cb0d263b2cf3a60041efc785b3971cb 297 Pfam PF03280 Proteobacterial lipase chaperone protein 96 280 1.5E-44 T 05-07-2017 IPR004961 Lipase chaperone GO:0006457|GO:0016020|GO:0051082 K08M4_RS15965 3cb0d263b2cf3a60041efc785b3971cb 297 SUPERFAMILY SSF158855 42 291 2.09E-61 T 05-07-2017 K08M4_RS10740 3181e2699c9b98c9e9471475a64fd510 304 SUPERFAMILY SSF51735 1 301 6.33E-44 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS10740 3181e2699c9b98c9e9471475a64fd510 304 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 221 1.3E-23 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 K08M4_RS10740 3181e2699c9b98c9e9471475a64fd510 304 Gene3D G3DSA:3.90.25.10 204 248 5.4E-4 T 05-07-2017 K08M4_RS10740 3181e2699c9b98c9e9471475a64fd510 304 Gene3D G3DSA:3.40.50.720 1 203 4.2E-24 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS10740 3181e2699c9b98c9e9471475a64fd510 304 Pfam PF08338 Domain of unknown function (DUF1731) 253 299 2.0E-13 T 05-07-2017 IPR013549 Domain of unknown function DUF1731 K08M4_RS10740 3181e2699c9b98c9e9471475a64fd510 304 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 296 2.1E-102 T 05-07-2017 IPR010099 Epimerase family protein SDR39U1 K08M4_RS17310 37683c53208dbb1097618a12ca383d1f 282 Gene3D G3DSA:3.40.250.10 152 278 2.0E-38 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS17310 37683c53208dbb1097618a12ca383d1f 282 SUPERFAMILY SSF52821 157 278 4.98E-29 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS17310 37683c53208dbb1097618a12ca383d1f 282 SMART SM00450 7 130 3.4E-15 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS17310 37683c53208dbb1097618a12ca383d1f 282 SMART SM00450 154 275 1.4E-14 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS17310 37683c53208dbb1097618a12ca383d1f 282 SUPERFAMILY SSF52821 2 137 2.62E-34 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS17310 37683c53208dbb1097618a12ca383d1f 282 Gene3D G3DSA:3.40.250.10 2 148 3.8E-38 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS17310 37683c53208dbb1097618a12ca383d1f 282 Pfam PF00581 Rhodanese-like domain 7 125 3.1E-14 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS17310 37683c53208dbb1097618a12ca383d1f 282 Pfam PF00581 Rhodanese-like domain 165 271 4.4E-9 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS12375 989453b889329fa0d00de8cca27b1eea 475 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 441 5.1E-160 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS12375 989453b889329fa0d00de8cca27b1eea 475 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 87 102 - T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS12375 989453b889329fa0d00de8cca27b1eea 475 Pfam PF01235 Sodium:alanine symporter family 48 452 1.6E-160 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS12375 989453b889329fa0d00de8cca27b1eea 475 PRINTS PR00175 Sodium/alanine symporter signature 87 109 7.4E-56 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS12375 989453b889329fa0d00de8cca27b1eea 475 PRINTS PR00175 Sodium/alanine symporter signature 303 321 7.4E-56 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS12375 989453b889329fa0d00de8cca27b1eea 475 PRINTS PR00175 Sodium/alanine symporter signature 178 196 7.4E-56 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS12375 989453b889329fa0d00de8cca27b1eea 475 PRINTS PR00175 Sodium/alanine symporter signature 206 225 7.4E-56 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS12375 989453b889329fa0d00de8cca27b1eea 475 PRINTS PR00175 Sodium/alanine symporter signature 410 430 7.4E-56 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS12375 989453b889329fa0d00de8cca27b1eea 475 PRINTS PR00175 Sodium/alanine symporter signature 349 371 7.4E-56 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS04825 b246bd94486d68a4cd5f7f79c55cda76 209 SUPERFAMILY SSF52833 1 193 1.46E-32 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS04825 b246bd94486d68a4cd5f7f79c55cda76 209 Pfam PF13743 Thioredoxin 10 175 7.0E-20 T 05-07-2017 K08M4_RS04825 b246bd94486d68a4cd5f7f79c55cda76 209 Gene3D G3DSA:3.40.30.10 8 40 2.5E-4 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS04825 b246bd94486d68a4cd5f7f79c55cda76 209 Gene3D G3DSA:3.40.30.10 162 201 2.5E-4 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS04825 b246bd94486d68a4cd5f7f79c55cda76 209 Gene3D G3DSA:1.10.472.60 48 161 2.1E-33 T 05-07-2017 IPR023169 UPF0413, central domain K08M4_RS21770 8264515c92dd76d8e70026270a54a340 506 Gene3D G3DSA:3.30.70.360 347 396 5.7E-20 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS21770 8264515c92dd76d8e70026270a54a340 506 Gene3D G3DSA:3.30.70.360 257 296 5.7E-20 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS21770 8264515c92dd76d8e70026270a54a340 506 Pfam PF07687 Peptidase dimerisation domain 244 395 1.2E-17 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS21770 8264515c92dd76d8e70026270a54a340 506 SUPERFAMILY SSF55031 348 395 9.6E-11 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS21770 8264515c92dd76d8e70026270a54a340 506 SUPERFAMILY SSF55031 248 291 9.6E-11 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS21770 8264515c92dd76d8e70026270a54a340 506 Pfam PF01546 Peptidase family M20/M25/M40 122 501 2.0E-34 T 05-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 K08M4_RS21770 8264515c92dd76d8e70026270a54a340 506 SUPERFAMILY SSF53187 48 236 2.73E-45 T 05-07-2017 K08M4_RS21770 8264515c92dd76d8e70026270a54a340 506 SUPERFAMILY SSF53187 411 503 2.73E-45 T 05-07-2017 K08M4_RS21770 8264515c92dd76d8e70026270a54a340 506 Gene3D G3DSA:3.40.630.10 51 256 1.9E-50 T 05-07-2017 K08M4_RS21770 8264515c92dd76d8e70026270a54a340 506 Gene3D G3DSA:3.40.630.10 437 504 1.9E-50 T 05-07-2017 K08M4_RS21810 211c9d39451a180f6d1c96a6e7a6d35b 309 PRINTS PR01469 Bacterial carbamate kinase signature 177 195 8.4E-60 T 05-07-2017 K08M4_RS21810 211c9d39451a180f6d1c96a6e7a6d35b 309 PRINTS PR01469 Bacterial carbamate kinase signature 207 222 8.4E-60 T 05-07-2017 K08M4_RS21810 211c9d39451a180f6d1c96a6e7a6d35b 309 PRINTS PR01469 Bacterial carbamate kinase signature 106 125 8.4E-60 T 05-07-2017 K08M4_RS21810 211c9d39451a180f6d1c96a6e7a6d35b 309 PRINTS PR01469 Bacterial carbamate kinase signature 41 60 8.4E-60 T 05-07-2017 K08M4_RS21810 211c9d39451a180f6d1c96a6e7a6d35b 309 PRINTS PR01469 Bacterial carbamate kinase signature 154 173 8.4E-60 T 05-07-2017 K08M4_RS21810 211c9d39451a180f6d1c96a6e7a6d35b 309 PRINTS PR01469 Bacterial carbamate kinase signature 257 272 8.4E-60 T 05-07-2017 K08M4_RS21810 211c9d39451a180f6d1c96a6e7a6d35b 309 PRINTS PR01469 Bacterial carbamate kinase signature 75 93 8.4E-60 T 05-07-2017 K08M4_RS21810 211c9d39451a180f6d1c96a6e7a6d35b 309 SUPERFAMILY SSF53633 1 300 1.22E-67 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS21810 211c9d39451a180f6d1c96a6e7a6d35b 309 PIRSF PIRSF000723 1 302 9.8E-101 T 05-07-2017 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 K08M4_RS21810 211c9d39451a180f6d1c96a6e7a6d35b 309 Pfam PF00696 Amino acid kinase family 1 276 1.1E-22 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS21810 211c9d39451a180f6d1c96a6e7a6d35b 309 Gene3D G3DSA:3.40.1160.10 1 302 3.4E-91 T 05-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase K08M4_RS12760 70ff733a16208079b89ca4e77d995ba3 228 SUPERFAMILY SSF109755 31 219 3.49E-15 T 05-07-2017 K08M4_RS12760 70ff733a16208079b89ca4e77d995ba3 228 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 6 227 4.4E-67 T 05-07-2017 IPR002727 Protein of unknown function DUF47 K08M4_RS12760 70ff733a16208079b89ca4e77d995ba3 228 Pfam PF01865 Protein of unknown function DUF47 9 225 1.2E-64 T 05-07-2017 IPR018445 Putative phosphate transport regulator K08M4_RS16525 66de990b8e4d936a452ee1d88236d6d2 402 Pfam PF12060 Domain of unknown function (DUF3541) 64 287 2.4E-113 T 05-07-2017 IPR021928 Protein of unknown function DUF3541 K08M4_RS02520 0fbe12bf9f8e7a9272526d36d02ff068 233 Gene3D G3DSA:3.90.550.10 7 231 2.1E-78 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS02520 0fbe12bf9f8e7a9272526d36d02ff068 233 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 8 229 4.5E-80 T 05-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 K08M4_RS02520 0fbe12bf9f8e7a9272526d36d02ff068 233 SUPERFAMILY SSF53448 8 229 4.23E-64 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS02520 0fbe12bf9f8e7a9272526d36d02ff068 233 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 9 228 1.3E-76 T 05-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 K08M4_RS02520 0fbe12bf9f8e7a9272526d36d02ff068 233 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 105 112 - T 05-07-2017 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 K08M4_RS02520 0fbe12bf9f8e7a9272526d36d02ff068 233 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 7 231 32.617 T 05-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 K08M4_RS08295 b17cfd5320c81748ad162e21ffd0360b 251 Pfam PF17131 Outer membrane lipoprotein-sorting protein 66 249 1.3E-65 T 05-07-2017 IPR033399 Putative outer membrane lipoprotein-sorting protein K08M4_RS08295 b17cfd5320c81748ad162e21ffd0360b 251 Gene3D G3DSA:2.50.20.10 13 249 5.9E-84 T 05-07-2017 K08M4_RS10325 ef92de836086b887c18773d3e0677997 574 SUPERFAMILY SSF52518 381 564 1.26E-22 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS10325 ef92de836086b887c18773d3e0677997 574 PIRSF PIRSF004983 3 574 8.0E-178 T 05-07-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 K08M4_RS10325 ef92de836086b887c18773d3e0677997 574 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 6 569 32.092 T 05-07-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 K08M4_RS10325 ef92de836086b887c18773d3e0677997 574 SUPERFAMILY SSF52467 226 349 1.45E-8 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain K08M4_RS10325 ef92de836086b887c18773d3e0677997 574 Gene3D G3DSA:3.40.50.970 373 561 2.4E-20 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS10325 ef92de836086b887c18773d3e0677997 574 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 12 445 3.6E-132 T 05-07-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 K08M4_RS10325 ef92de836086b887c18773d3e0677997 574 Gene3D G3DSA:3.40.50.1220 239 343 9.3E-6 T 05-07-2017 IPR029035 DHS-like NAD/FAD-binding domain K08M4_RS10325 ef92de836086b887c18773d3e0677997 574 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 142 1.5E-26 T 05-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 K08M4_RS10325 ef92de836086b887c18773d3e0677997 574 Gene3D G3DSA:3.40.50.970 12 183 1.4E-40 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS10325 ef92de836086b887c18773d3e0677997 574 SUPERFAMILY SSF52518 10 183 1.34E-27 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS10325 ef92de836086b887c18773d3e0677997 574 Pfam PF16582 Middle domain of thiamine pyrophosphate 189 404 4.2E-37 T 05-07-2017 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 K08M4_RS11150 f496c316b05e3a273a1a8d7eebdb7f0c 1159 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 292 735 5.9E-172 T 05-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS11150 f496c316b05e3a273a1a8d7eebdb7f0c 1159 Gene3D G3DSA:2.40.50.140 988 1076 1.9E-9 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS11150 f496c316b05e3a273a1a8d7eebdb7f0c 1159 SUPERFAMILY SSF50249 976 1064 1.83E-5 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS11150 f496c316b05e3a273a1a8d7eebdb7f0c 1159 Gene3D G3DSA:1.10.150.280 836 882 2.2E-6 T 05-07-2017 K08M4_RS11150 f496c316b05e3a273a1a8d7eebdb7f0c 1159 SMART SM00481 7 74 2.2E-24 T 05-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 K08M4_RS11150 f496c316b05e3a273a1a8d7eebdb7f0c 1159 Gene3D G3DSA:3.20.20.140 5 257 2.8E-15 T 05-07-2017 K08M4_RS11150 f496c316b05e3a273a1a8d7eebdb7f0c 1159 Pfam PF01336 OB-fold nucleic acid binding domain 999 1071 1.3E-10 T 05-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 K08M4_RS11150 f496c316b05e3a273a1a8d7eebdb7f0c 1159 SUPERFAMILY SSF89550 5 263 2.35E-10 T 05-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 K08M4_RS11150 f496c316b05e3a273a1a8d7eebdb7f0c 1159 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1030 0.0 T 05-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS11150 f496c316b05e3a273a1a8d7eebdb7f0c 1159 Pfam PF14579 Helix-hairpin-helix motif 809 897 3.5E-24 T 05-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 K08M4_RS11150 f496c316b05e3a273a1a8d7eebdb7f0c 1159 Pfam PF02811 PHP domain 8 172 9.9E-41 T 05-07-2017 IPR004013 PHP domain GO:0003824 K08M4_RS03055 d360f801be0d2bf52979615052d5aca7 477 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 33 442 3.7E-96 T 05-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 K08M4_RS03055 d360f801be0d2bf52979615052d5aca7 477 Gene3D G3DSA:3.40.710.10 217 447 4.6E-58 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS03055 d360f801be0d2bf52979615052d5aca7 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 336 350 6.9E-26 T 05-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 K08M4_RS03055 d360f801be0d2bf52979615052d5aca7 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 415 428 6.9E-26 T 05-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 K08M4_RS03055 d360f801be0d2bf52979615052d5aca7 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 277 299 6.9E-26 T 05-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 K08M4_RS03055 d360f801be0d2bf52979615052d5aca7 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 351 365 6.9E-26 T 05-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 K08M4_RS03055 d360f801be0d2bf52979615052d5aca7 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 58 77 6.9E-26 T 05-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 K08M4_RS03055 d360f801be0d2bf52979615052d5aca7 477 SUPERFAMILY SSF56601 28 445 5.64E-84 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS03055 d360f801be0d2bf52979615052d5aca7 477 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 52 437 1.2E-96 T 05-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 K08M4_RS09185 aa7c0c9e20e169bb131305f030a51495 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS09185 aa7c0c9e20e169bb131305f030a51495 214 SMART SM00448 2 115 1.4E-28 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS09185 aa7c0c9e20e169bb131305f030a51495 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 1.1E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS09185 aa7c0c9e20e169bb131305f030a51495 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 1.1E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS09185 aa7c0c9e20e169bb131305f030a51495 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 1.1E-10 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS09185 aa7c0c9e20e169bb131305f030a51495 214 SUPERFAMILY SSF52172 2 132 3.84E-33 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS09185 aa7c0c9e20e169bb131305f030a51495 214 Pfam PF00072 Response regulator receiver domain 4 116 8.3E-31 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS09185 aa7c0c9e20e169bb131305f030a51495 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 1.6E-19 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS09185 aa7c0c9e20e169bb131305f030a51495 214 Gene3D G3DSA:3.40.50.2300 2 122 9.9E-34 T 05-07-2017 K08M4_RS09185 aa7c0c9e20e169bb131305f030a51495 214 SUPERFAMILY SSF46894 135 210 9.52E-19 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS09185 aa7c0c9e20e169bb131305f030a51495 214 Gene3D G3DSA:1.10.10.10 123 211 6.5E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS09185 aa7c0c9e20e169bb131305f030a51495 214 SMART SM00421 146 203 1.7E-16 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS20925 aae0a76046824a46e02c8cab16a19071 141 Pfam PF11215 Protein of unknown function (DUF3010) 1 137 2.8E-61 T 05-07-2017 IPR021378 Protein of unknown function DUF3010 K08M4_RS09740 62cd96eed33d82f21c93efe3584ba2fa 400 Gene3D G3DSA:3.40.50.150 107 185 9.9E-6 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS09740 62cd96eed33d82f21c93efe3584ba2fa 400 SUPERFAMILY SSF53335 119 202 2.25E-6 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS09740 62cd96eed33d82f21c93efe3584ba2fa 400 Pfam PF13679 Methyltransferase domain 112 230 1.1E-16 T 05-07-2017 IPR025714 Methyltransferase domain K08M4_RS11045 905f42489438f7de596a64199b139ea5 145 Pfam PF09842 Predicted membrane protein (DUF2069) 19 121 1.1E-32 T 05-07-2017 IPR018643 Protein of unknown function DUF2069, membrane K08M4_RS07095 542091159ff524ae80f4a92c121432f5 135 Gene3D G3DSA:3.10.180.10 4 134 4.2E-44 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS07095 542091159ff524ae80f4a92c121432f5 135 SUPERFAMILY SSF54593 7 134 2.02E-12 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS12935 32d684960ada80f5209038229b92e1ef 200 SUPERFAMILY SSF52016 1 197 2.16E-60 T 05-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel K08M4_RS12935 32d684960ada80f5209038229b92e1ef 200 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 199 44.19 T 05-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 K08M4_RS12935 32d684960ada80f5209038229b92e1ef 200 Gene3D G3DSA:3.20.19.10 1 194 7.0E-49 T 05-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel K08M4_RS12935 32d684960ada80f5209038229b92e1ef 200 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 188 5.2E-98 T 05-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 K08M4_RS12935 32d684960ada80f5209038229b92e1ef 200 Pfam PF00694 Aconitase C-terminal domain 1 125 3.1E-39 T 05-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 K08M4_RS06660 59bad3bbf715c93d53f078ba7834eaa2 78 Pfam PF00462 Glutaredoxin 4 60 5.1E-10 T 05-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 K08M4_RS06660 59bad3bbf715c93d53f078ba7834eaa2 78 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 05-07-2017 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 K08M4_RS06660 59bad3bbf715c93d53f078ba7834eaa2 78 Gene3D G3DSA:3.40.30.10 3 74 1.1E-17 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS06660 59bad3bbf715c93d53f078ba7834eaa2 78 SUPERFAMILY SSF52833 2 68 1.31E-12 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS21320 76e359b955af6211ec22dbaba70e2950 382 SUPERFAMILY SSF53383 3 381 2.95E-89 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS21320 76e359b955af6211ec22dbaba70e2950 382 Gene3D G3DSA:3.90.1150.10 261 381 2.4E-12 T 05-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 K08M4_RS21320 76e359b955af6211ec22dbaba70e2950 382 Pfam PF00155 Aminotransferase class I and II 27 375 7.7E-33 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS21320 76e359b955af6211ec22dbaba70e2950 382 Gene3D G3DSA:3.40.640.10 55 260 3.1E-64 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS10475 08e36d1496a563b3ed7903fc8312e0fb 186 Pfam PF03843 Outer membrane lipoprotein Slp family 21 163 7.6E-40 T 05-07-2017 IPR004658 Outer membrane lipoprotein Slp GO:0019867 K08M4_RS10475 08e36d1496a563b3ed7903fc8312e0fb 186 TIGRFAM TIGR00752 slp: outer membrane lipoprotein, Slp family 11 158 1.7E-34 T 05-07-2017 IPR004658 Outer membrane lipoprotein Slp GO:0019867 K08M4_RS10475 08e36d1496a563b3ed7903fc8312e0fb 186 PIRSF PIRSF004982 5 186 1.8E-52 T 05-07-2017 IPR004658 Outer membrane lipoprotein Slp GO:0019867 K08M4_RS14845 f96139f0dc9a2b59aecbeaf857e9f0e6 328 Gene3D G3DSA:3.30.200.20 37 107 1.9E-4 T 05-07-2017 K08M4_RS14845 f96139f0dc9a2b59aecbeaf857e9f0e6 328 Pfam PF01636 Phosphotransferase enzyme family 36 256 6.4E-41 T 05-07-2017 IPR002575 Aminoglycoside phosphotransferase K08M4_RS14845 f96139f0dc9a2b59aecbeaf857e9f0e6 328 SUPERFAMILY SSF56112 6 328 7.29E-92 T 05-07-2017 IPR011009 Protein kinase-like domain K08M4_RS14845 f96139f0dc9a2b59aecbeaf857e9f0e6 328 Hamap MF_01497 Stress response kinase A [srkA]. 4 318 46.639 T 05-07-2017 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 K08M4_RS14845 f96139f0dc9a2b59aecbeaf857e9f0e6 328 Gene3D G3DSA:3.90.1200.10 108 326 7.8E-49 T 05-07-2017 K08M4_RS07245 d3ef7e2574cfa218636c0e820ba43943 269 Gene3D G3DSA:3.40.50.150 16 264 6.8E-29 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS07245 d3ef7e2574cfa218636c0e820ba43943 269 Pfam PF08241 Methyltransferase domain 46 144 4.3E-13 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 K08M4_RS07245 d3ef7e2574cfa218636c0e820ba43943 269 SUPERFAMILY SSF53335 19 219 3.08E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS21245 b63b695756c7a25ffbf93ccc8e9d75c5 449 TIGRFAM TIGR03356 BGL: beta-galactosidase 14 437 6.1E-184 T 05-07-2017 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 K08M4_RS21245 b63b695756c7a25ffbf93ccc8e9d75c5 449 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 17 31 - T 05-07-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site K08M4_RS21245 b63b695756c7a25ffbf93ccc8e9d75c5 449 PRINTS PR00131 Glycosyl hydrolase family 1 signature 370 381 5.6E-23 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 K08M4_RS21245 b63b695756c7a25ffbf93ccc8e9d75c5 449 PRINTS PR00131 Glycosyl hydrolase family 1 signature 415 427 5.6E-23 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 K08M4_RS21245 b63b695756c7a25ffbf93ccc8e9d75c5 449 PRINTS PR00131 Glycosyl hydrolase family 1 signature 289 303 5.6E-23 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 K08M4_RS21245 b63b695756c7a25ffbf93ccc8e9d75c5 449 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 408 5.6E-23 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 K08M4_RS21245 b63b695756c7a25ffbf93ccc8e9d75c5 449 PRINTS PR00131 Glycosyl hydrolase family 1 signature 350 358 5.6E-23 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 K08M4_RS21245 b63b695756c7a25ffbf93ccc8e9d75c5 449 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 350 358 - T 05-07-2017 IPR018120 Glycoside hydrolase family 1, active site K08M4_RS21245 b63b695756c7a25ffbf93ccc8e9d75c5 449 Gene3D G3DSA:3.20.20.80 15 445 1.8E-156 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS21245 b63b695756c7a25ffbf93ccc8e9d75c5 449 Pfam PF00232 Glycosyl hydrolase family 1 15 441 4.4E-153 T 05-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 K08M4_RS21245 b63b695756c7a25ffbf93ccc8e9d75c5 449 SUPERFAMILY SSF51445 15 441 1.68E-156 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS11625 b39425e1ec187c9e163aacdecb6a8d89 343 SUPERFAMILY SSF51161 90 324 1.66E-35 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS11625 b39425e1ec187c9e163aacdecb6a8d89 343 Gene3D G3DSA:2.160.10.10 173 340 2.4E-33 T 05-07-2017 K08M4_RS11625 b39425e1ec187c9e163aacdecb6a8d89 343 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 253 285 5.9E-13 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS11625 b39425e1ec187c9e163aacdecb6a8d89 343 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 131 171 2.4E-16 T 05-07-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 K08M4_RS11625 b39425e1ec187c9e163aacdecb6a8d89 343 Gene3D G3DSA:3.30.60.70 131 171 4.7E-22 T 05-07-2017 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 K08M4_RS11625 b39425e1ec187c9e163aacdecb6a8d89 343 TIGRFAM TIGR03536 DapD_gpp: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 3 343 3.3E-180 T 05-07-2017 IPR019876 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, gammaproteobacteria KEGG: 00300+2.3.1.117 K08M4_RS11625 b39425e1ec187c9e163aacdecb6a8d89 343 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 2 340 46.288 T 05-07-2017 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 K08M4_RS15415 3ecf16ee751f40a46df79a655af1cf40 90 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 2 32 3.5E-5 T 05-07-2017 IPR011723 Zinc finger/thioredoxin putative K08M4_RS20890 b266f04bb5599ed6a28408e2e54dc5f3 301 Gene3D G3DSA:3.40.190.10 90 188 1.6E-14 T 05-07-2017 K08M4_RS20890 b266f04bb5599ed6a28408e2e54dc5f3 301 SUPERFAMILY SSF53850 90 298 2.71E-26 T 05-07-2017 K08M4_RS20890 b266f04bb5599ed6a28408e2e54dc5f3 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 6.0E-17 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS20890 b266f04bb5599ed6a28408e2e54dc5f3 301 SUPERFAMILY SSF46785 2 110 1.85E-19 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20890 b266f04bb5599ed6a28408e2e54dc5f3 301 Pfam PF03466 LysR substrate binding domain 89 296 4.1E-25 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS20890 b266f04bb5599ed6a28408e2e54dc5f3 301 Gene3D G3DSA:3.40.190.10 189 267 1.1E-4 T 05-07-2017 K08M4_RS20890 b266f04bb5599ed6a28408e2e54dc5f3 301 Gene3D G3DSA:1.10.10.10 2 85 3.1E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS02940 01fc15f897d14fd307e57f965ac715a7 338 Gene3D G3DSA:3.40.190.10 121 285 3.4E-59 T 05-07-2017 K08M4_RS02940 01fc15f897d14fd307e57f965ac715a7 338 PIRSF PIRSF002825 1 338 1.3E-97 T 05-07-2017 IPR026045 Ferric binding protein K08M4_RS02940 01fc15f897d14fd307e57f965ac715a7 338 Gene3D G3DSA:3.40.190.10 23 115 2.4E-19 T 05-07-2017 K08M4_RS02940 01fc15f897d14fd307e57f965ac715a7 338 SUPERFAMILY SSF53850 25 333 5.67E-74 T 05-07-2017 K08M4_RS02940 01fc15f897d14fd307e57f965ac715a7 338 Pfam PF13343 Bacterial extracellular solute-binding protein 73 301 9.5E-17 T 05-07-2017 K08M4_RS21120 8efb4c729835cf60a2c124e1f16ccc3e 175 Pfam PF00583 Acetyltransferase (GNAT) family 74 149 1.8E-11 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS21120 8efb4c729835cf60a2c124e1f16ccc3e 175 Gene3D G3DSA:3.40.630.30 1 173 5.7E-23 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS21120 8efb4c729835cf60a2c124e1f16ccc3e 175 SUPERFAMILY SSF55729 1 174 9.61E-21 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS17150 7e2d3aff8efe6a6021efed75dfb92f4e 308 SUPERFAMILY SSF103481 48 140 2.48E-6 T 05-07-2017 K08M4_RS17150 7e2d3aff8efe6a6021efed75dfb92f4e 308 SUPERFAMILY SSF103481 208 290 2.62E-7 T 05-07-2017 K08M4_RS17150 7e2d3aff8efe6a6021efed75dfb92f4e 308 Pfam PF00892 EamA-like transporter family 160 285 1.0E-8 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS17150 7e2d3aff8efe6a6021efed75dfb92f4e 308 Pfam PF00892 EamA-like transporter family 9 137 1.9E-6 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS01245 8048f8bd6180d2ba4c0c24991670944c 297 SUPERFAMILY SSF46785 1 86 3.66E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS01245 8048f8bd6180d2ba4c0c24991670944c 297 Gene3D G3DSA:3.40.190.10 90 175 1.7E-18 T 05-07-2017 K08M4_RS01245 8048f8bd6180d2ba4c0c24991670944c 297 Gene3D G3DSA:3.40.190.10 176 267 1.6E-32 T 05-07-2017 K08M4_RS01245 8048f8bd6180d2ba4c0c24991670944c 297 Pfam PF03466 LysR substrate binding domain 90 293 5.8E-43 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS01245 8048f8bd6180d2ba4c0c24991670944c 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.4E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS01245 8048f8bd6180d2ba4c0c24991670944c 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.4E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS01245 8048f8bd6180d2ba4c0c24991670944c 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.4E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS01245 8048f8bd6180d2ba4c0c24991670944c 297 SUPERFAMILY SSF53850 89 295 8.53E-39 T 05-07-2017 K08M4_RS01245 8048f8bd6180d2ba4c0c24991670944c 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.6E-18 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS01245 8048f8bd6180d2ba4c0c24991670944c 297 Gene3D G3DSA:1.10.10.10 1 82 3.9E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS18680 ddb17f8b35aa97ee9a645de57d0450b2 141 Pfam PF03061 Thioesterase superfamily 52 128 1.2E-14 T 05-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 K08M4_RS18680 ddb17f8b35aa97ee9a645de57d0450b2 141 Gene3D G3DSA:3.10.129.10 1 140 3.5E-52 T 05-07-2017 IPR029069 HotDog domain K08M4_RS18680 ddb17f8b35aa97ee9a645de57d0450b2 141 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 21 135 3.0E-38 T 05-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 K08M4_RS18680 ddb17f8b35aa97ee9a645de57d0450b2 141 SUPERFAMILY SSF54637 1 139 4.78E-31 T 05-07-2017 IPR029069 HotDog domain K08M4_RS01830 5a07f9f883d58ef91b6e5d288b39192f 185 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 24 138 2.0E-13 T 05-07-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 K08M4_RS01830 5a07f9f883d58ef91b6e5d288b39192f 185 PIRSF PIRSF006118 10 185 4.4E-75 T 05-07-2017 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 K08M4_RS01830 5a07f9f883d58ef91b6e5d288b39192f 185 Pfam PF08282 haloacid dehalogenase-like hydrolase 92 158 4.9E-10 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS01830 5a07f9f883d58ef91b6e5d288b39192f 185 Gene3D G3DSA:3.40.50.1000 13 175 1.5E-46 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS01830 5a07f9f883d58ef91b6e5d288b39192f 185 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 23 175 1.2E-63 T 05-07-2017 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 K08M4_RS01830 5a07f9f883d58ef91b6e5d288b39192f 185 SUPERFAMILY SSF56784 21 178 7.74E-42 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS03355 eeca4a8b95568c9b32c440270f4f8a07 485 PRINTS PR00811 Bacterial general secretion pathway protein D signature 251 275 3.6E-12 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS03355 eeca4a8b95568c9b32c440270f4f8a07 485 PRINTS PR00811 Bacterial general secretion pathway protein D signature 178 188 3.6E-12 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS03355 eeca4a8b95568c9b32c440270f4f8a07 485 PRINTS PR00811 Bacterial general secretion pathway protein D signature 385 403 3.6E-12 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS03355 eeca4a8b95568c9b32c440270f4f8a07 485 PRINTS PR00811 Bacterial general secretion pathway protein D signature 408 422 3.6E-12 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS03355 eeca4a8b95568c9b32c440270f4f8a07 485 Pfam PF13629 Pilus formation protein N terminal region 26 95 4.9E-19 T 05-07-2017 IPR032789 Pilus formation protein, N-terminal K08M4_RS03355 eeca4a8b95568c9b32c440270f4f8a07 485 Pfam PF00263 Bacterial type II and III secretion system protein 256 419 2.3E-39 T 05-07-2017 IPR004846 Type II/III secretion system GO:0009306 K08M4_RS07415 13146b671ba0f8d34237e4af3d27898c 67 Pfam PF14255 Cysteine-rich CPXCG 9 59 8.1E-21 T 05-07-2017 IPR025990 Cysteine-rich CPXCG protein K08M4_RS07415 13146b671ba0f8d34237e4af3d27898c 67 PIRSF PIRSF037225 1 65 6.7E-25 T 05-07-2017 IPR017143 Uncharacterised conserved protein UCP037225 K08M4_RS09855 1df29ae7327baf28463dbc1e23090cb5 429 Gene3D G3DSA:3.50.50.60 179 348 1.4E-27 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS09855 1df29ae7327baf28463dbc1e23090cb5 429 SUPERFAMILY SSF51905 3 103 4.21E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS09855 1df29ae7327baf28463dbc1e23090cb5 429 SUPERFAMILY SSF51905 220 347 4.21E-28 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS09855 1df29ae7327baf28463dbc1e23090cb5 429 Gene3D G3DSA:3.50.50.60 3 178 8.4E-22 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS09855 1df29ae7327baf28463dbc1e23090cb5 429 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 333 2.9E-61 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS09855 1df29ae7327baf28463dbc1e23090cb5 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 5.0E-14 T 05-07-2017 K08M4_RS09855 1df29ae7327baf28463dbc1e23090cb5 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 5.0E-14 T 05-07-2017 K08M4_RS09855 1df29ae7327baf28463dbc1e23090cb5 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 5.0E-14 T 05-07-2017 K08M4_RS09855 1df29ae7327baf28463dbc1e23090cb5 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.0E-14 T 05-07-2017 K08M4_RS09855 1df29ae7327baf28463dbc1e23090cb5 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 192 5.5E-8 T 05-07-2017 K08M4_RS09855 1df29ae7327baf28463dbc1e23090cb5 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 5.5E-8 T 05-07-2017 K08M4_RS09855 1df29ae7327baf28463dbc1e23090cb5 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 5.5E-8 T 05-07-2017 K08M4_RS09145 68584a925c4ece8d92f5d2c7118ef6d2 416 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 149 394 4.6E-29 T 05-07-2017 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 K08M4_RS09145 68584a925c4ece8d92f5d2c7118ef6d2 416 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 144 8.8E-33 T 05-07-2017 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 K08M4_RS09145 68584a925c4ece8d92f5d2c7118ef6d2 416 SUPERFAMILY SSF51735 3 179 1.37E-15 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS09145 68584a925c4ece8d92f5d2c7118ef6d2 416 Gene3D G3DSA:3.40.50.720 2 196 2.4E-31 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS11020 38e7dfe4a73d5510afd45dc767d491c8 358 Pfam PF01594 Domain of unknown function DUF20 20 345 8.0E-74 T 05-07-2017 IPR002549 Transmembrane protein TqsA-like K08M4_RS09285 d70ab9b0ba4b11eedbe5ad2ed2d5386d 538 Gene3D G3DSA:1.10.287.950 290 506 2.7E-53 T 05-07-2017 K08M4_RS09285 d70ab9b0ba4b11eedbe5ad2ed2d5386d 538 SUPERFAMILY SSF58104 235 537 4.84E-72 T 05-07-2017 K08M4_RS09285 d70ab9b0ba4b11eedbe5ad2ed2d5386d 538 Pfam PF00672 HAMP domain 188 256 8.5E-17 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS09285 d70ab9b0ba4b11eedbe5ad2ed2d5386d 538 SMART SM00304 207 260 1.4E-10 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS09285 d70ab9b0ba4b11eedbe5ad2ed2d5386d 538 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 322 535 1.8E-47 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS09285 d70ab9b0ba4b11eedbe5ad2ed2d5386d 538 SMART SM00283 275 536 1.3E-68 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS08740 c44043e8f76d5d6d172bd40579269746 231 SMART SM00363 1 62 3.3E-5 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS08740 c44043e8f76d5d6d172bd40579269746 231 SUPERFAMILY SSF55120 60 226 1.34E-44 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS08740 c44043e8f76d5d6d172bd40579269746 231 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 65 223 4.0E-49 T 05-07-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 K08M4_RS08740 c44043e8f76d5d6d172bd40579269746 231 Pfam PF01479 S4 domain 1 44 3.7E-7 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS08740 c44043e8f76d5d6d172bd40579269746 231 SUPERFAMILY SSF55174 1 56 2.65E-11 T 05-07-2017 K08M4_RS08740 c44043e8f76d5d6d172bd40579269746 231 Gene3D G3DSA:2.30.29.30 44 135 8.8E-4 T 05-07-2017 IPR011993 PH domain-like K08M4_RS08740 c44043e8f76d5d6d172bd40579269746 231 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 98 112 - T 05-07-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 K08M4_RS08740 c44043e8f76d5d6d172bd40579269746 231 Gene3D G3DSA:3.10.290.10 1 43 4.2E-17 T 05-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 K08M4_RS08740 c44043e8f76d5d6d172bd40579269746 231 Pfam PF00849 RNA pseudouridylate synthase 61 191 1.5E-17 T 05-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS03370 2059bef26fc2fdc41984a523793358d3 142 Pfam PF07811 TadE-like protein 10 52 2.4E-7 T 05-07-2017 IPR012495 TadE-like K08M4_RS04705 48a667467858d445c85164c891de47fd 666 SUPERFAMILY SSF51395 2 361 1.7E-108 T 05-07-2017 K08M4_RS04705 48a667467858d445c85164c891de47fd 666 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 376 395 2.3E-9 T 05-07-2017 K08M4_RS04705 48a667467858d445c85164c891de47fd 666 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 496 514 2.3E-9 T 05-07-2017 K08M4_RS04705 48a667467858d445c85164c891de47fd 666 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 327 2.9E-83 T 05-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 K08M4_RS04705 48a667467858d445c85164c891de47fd 666 Gene3D G3DSA:3.20.20.70 1 358 5.1E-120 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS04705 48a667467858d445c85164c891de47fd 666 SUPERFAMILY SSF51971 332 515 7.3E-41 T 05-07-2017 K08M4_RS04705 48a667467858d445c85164c891de47fd 666 Gene3D G3DSA:3.50.50.60 468 619 2.0E-44 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS04705 48a667467858d445c85164c891de47fd 666 Gene3D G3DSA:3.50.50.60 359 463 1.6E-26 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS04705 48a667467858d445c85164c891de47fd 666 SUPERFAMILY SSF51905 467 621 2.5E-19 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS04705 48a667467858d445c85164c891de47fd 666 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 375 625 1.8E-25 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS04305 b484b555856f864ee6079b4f2ceb9fb5 160 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 2 145 31.466 T 05-07-2017 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 K08M4_RS04305 b484b555856f864ee6079b4f2ceb9fb5 160 Gene3D G3DSA:2.40.50.140 26 129 6.7E-38 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS04305 b484b555856f864ee6079b4f2ceb9fb5 160 SUPERFAMILY SSF82093 30 141 1.07E-37 T 05-07-2017 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 K08M4_RS04305 b484b555856f864ee6079b4f2ceb9fb5 160 Pfam PF03100 CcmE 4 134 1.3E-43 T 05-07-2017 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 K08M4_RS15075 7b6d376c947e97d72436a8aef64720a1 324 Gene3D G3DSA:3.75.10.10 15 311 1.2E-28 T 05-07-2017 K08M4_RS15075 7b6d376c947e97d72436a8aef64720a1 324 PIRSF PIRSF028188 2 320 1.4E-143 T 05-07-2017 IPR014541 Predicted amidinotransferase, FN0238 type K08M4_RS15075 7b6d376c947e97d72436a8aef64720a1 324 SUPERFAMILY SSF55909 18 312 2.8E-35 T 05-07-2017 K08M4_RS15075 7b6d376c947e97d72436a8aef64720a1 324 Pfam PF02274 Amidinotransferase 22 316 3.1E-66 T 05-07-2017 K08M4_RS13110 31c112bd0a3ef454f32d329f76a011ea 347 Gene3D G3DSA:3.30.420.40 9 163 2.4E-46 T 05-07-2017 K08M4_RS13110 31c112bd0a3ef454f32d329f76a011ea 347 Gene3D G3DSA:3.90.640.10 191 263 6.9E-31 T 05-07-2017 K08M4_RS13110 31c112bd0a3ef454f32d329f76a011ea 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 339 1.0E-165 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 K08M4_RS13110 31c112bd0a3ef454f32d329f76a011ea 347 Pfam PF06723 MreB/Mbl protein 11 338 1.4E-148 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 K08M4_RS13110 31c112bd0a3ef454f32d329f76a011ea 347 Gene3D G3DSA:3.30.420.40 267 321 2.5E-35 T 05-07-2017 K08M4_RS13110 31c112bd0a3ef454f32d329f76a011ea 347 Gene3D G3DSA:3.30.420.40 164 190 2.5E-35 T 05-07-2017 K08M4_RS13110 31c112bd0a3ef454f32d329f76a011ea 347 SUPERFAMILY SSF53067 154 340 1.39E-50 T 05-07-2017 K08M4_RS13110 31c112bd0a3ef454f32d329f76a011ea 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 52 70 1.6E-63 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 K08M4_RS13110 31c112bd0a3ef454f32d329f76a011ea 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 304 330 1.6E-63 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 K08M4_RS13110 31c112bd0a3ef454f32d329f76a011ea 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 136 155 1.6E-63 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 K08M4_RS13110 31c112bd0a3ef454f32d329f76a011ea 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 191 211 1.6E-63 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 K08M4_RS13110 31c112bd0a3ef454f32d329f76a011ea 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 72 95 1.6E-63 T 05-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 K08M4_RS13110 31c112bd0a3ef454f32d329f76a011ea 347 SUPERFAMILY SSF53067 9 152 1.78E-37 T 05-07-2017 K08M4_RS04600 54b9cde2aff8176fea0cf013b2ad556a 123 PIRSF PIRSF016789 1 116 4.4E-38 T 05-07-2017 IPR007401 Protein of unknown function DUF454 K08M4_RS04600 54b9cde2aff8176fea0cf013b2ad556a 123 Pfam PF04304 Protein of unknown function (DUF454) 2 110 6.1E-35 T 05-07-2017 IPR007401 Protein of unknown function DUF454 K08M4_RS18485 e9356ced615b43766d5a6ac48e24a135 413 SUPERFAMILY SSF55073 243 411 6.83E-32 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS18485 e9356ced615b43766d5a6ac48e24a135 413 Pfam PF00990 Diguanylate cyclase, GGDEF domain 364 408 1.5E-5 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS18485 e9356ced615b43766d5a6ac48e24a135 413 Pfam PF00990 Diguanylate cyclase, GGDEF domain 239 348 3.5E-22 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS18485 e9356ced615b43766d5a6ac48e24a135 413 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 237 346 1.8E-23 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS18485 e9356ced615b43766d5a6ac48e24a135 413 Gene3D G3DSA:3.30.70.270 240 411 3.2E-39 T 05-07-2017 K08M4_RS18485 e9356ced615b43766d5a6ac48e24a135 413 SMART SM00267 227 412 1.6E-30 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS08990 5a3ba68f6f951a5a8f771a100649adde 364 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 42 329 9.3E-73 T 05-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 K08M4_RS08990 5a3ba68f6f951a5a8f771a100649adde 364 PIRSF PIRSF039026 6 364 6.1E-143 T 05-07-2017 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like K08M4_RS04220 97171d843bdf1fa83e5bd17429be5d0f 376 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 7 353 1.6E-135 T 05-07-2017 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 K08M4_RS04220 97171d843bdf1fa83e5bd17429be5d0f 376 Gene3D G3DSA:3.40.1690.10 218 357 4.3E-62 T 05-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal K08M4_RS04220 97171d843bdf1fa83e5bd17429be5d0f 376 Pfam PF01312 FlhB HrpN YscU SpaS Family 7 347 1.1E-121 T 05-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 K08M4_RS04220 97171d843bdf1fa83e5bd17429be5d0f 376 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 10 32 1.1E-38 T 05-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 K08M4_RS04220 97171d843bdf1fa83e5bd17429be5d0f 376 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 302 323 1.1E-38 T 05-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 K08M4_RS04220 97171d843bdf1fa83e5bd17429be5d0f 376 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 208 226 1.1E-38 T 05-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 K08M4_RS04220 97171d843bdf1fa83e5bd17429be5d0f 376 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 228 245 1.1E-38 T 05-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 K08M4_RS04220 97171d843bdf1fa83e5bd17429be5d0f 376 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 272 287 1.1E-38 T 05-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 K08M4_RS04220 97171d843bdf1fa83e5bd17429be5d0f 376 SUPERFAMILY SSF160544 250 355 1.27E-39 T 05-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal K08M4_RS00085 8b83db5c30d9f97c1d9d640452041554 207 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 5 201 4.5E-62 T 05-07-2017 IPR015796 Impact family, bacterial/archaeal K08M4_RS00085 8b83db5c30d9f97c1d9d640452041554 207 Pfam PF09186 Domain of unknown function (DUF1949) 143 196 5.7E-10 T 05-07-2017 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal K08M4_RS00085 8b83db5c30d9f97c1d9d640452041554 207 SUPERFAMILY SSF54980 139 203 3.6E-7 T 05-07-2017 IPR009022 Elongation factor G, III-V domain K08M4_RS00085 8b83db5c30d9f97c1d9d640452041554 207 Pfam PF01205 Uncharacterized protein family UPF0029 20 127 3.7E-25 T 05-07-2017 IPR001498 Impact, N-terminal K08M4_RS00085 8b83db5c30d9f97c1d9d640452041554 207 Gene3D G3DSA:3.30.230.30 8 135 4.6E-41 T 05-07-2017 IPR001498 Impact, N-terminal K08M4_RS00085 8b83db5c30d9f97c1d9d640452041554 207 SUPERFAMILY SSF54211 5 134 7.21E-41 T 05-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold K08M4_RS00085 8b83db5c30d9f97c1d9d640452041554 207 Gene3D G3DSA:3.30.70.240 139 205 2.8E-8 T 05-07-2017 IPR000640 Translation elongation factor EFG, V domain K08M4_RS01335 8bc7282d0e1ec0f5c6f0e881e7385461 339 Pfam PF04958 Arginine N-succinyltransferase beta subunit 1 337 1.2E-138 T 05-07-2017 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 K08M4_RS01335 8bc7282d0e1ec0f5c6f0e881e7385461 339 TIGRFAM TIGR03244 arg_catab_AstA: arginine N-succinyltransferase 3 338 2.2E-133 T 05-07-2017 IPR017650 Arginine N-succinyltransferase GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 K08M4_RS01335 8bc7282d0e1ec0f5c6f0e881e7385461 339 Gene3D G3DSA:2.40.40.20 278 339 5.2E-15 T 05-07-2017 K08M4_RS01335 8bc7282d0e1ec0f5c6f0e881e7385461 339 SUPERFAMILY SSF55729 1 337 7.56E-131 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS01335 8bc7282d0e1ec0f5c6f0e881e7385461 339 TIGRFAM TIGR03243 arg_catab_AOST: arginine and ornithine succinyltransferase subunits 3 338 7.2E-132 T 05-07-2017 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 K08M4_RS17685 13bc4d156e9a3ea0b11d66181c8599dc 343 Pfam PF16884 N-terminal domain of oxidoreductase 7 113 7.8E-41 T 05-07-2017 K08M4_RS17685 13bc4d156e9a3ea0b11d66181c8599dc 343 SUPERFAMILY SSF51735 125 304 5.98E-48 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS17685 13bc4d156e9a3ea0b11d66181c8599dc 343 Pfam PF00107 Zinc-binding dehydrogenase 159 292 3.1E-21 T 05-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 K08M4_RS17685 13bc4d156e9a3ea0b11d66181c8599dc 343 SMART SM00829 20 337 2.9E-4 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 K08M4_RS17685 13bc4d156e9a3ea0b11d66181c8599dc 343 Gene3D G3DSA:3.90.180.10 2 140 2.3E-52 T 05-07-2017 IPR011032 GroES-like K08M4_RS17685 13bc4d156e9a3ea0b11d66181c8599dc 343 Gene3D G3DSA:3.40.50.720 141 306 8.1E-67 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS17685 13bc4d156e9a3ea0b11d66181c8599dc 343 SUPERFAMILY SSF50129 6 144 3.86E-41 T 05-07-2017 IPR011032 GroES-like K08M4_RS06635 1d37d55a5dc93efcaac16655a77db38e 191 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 19 83 5.2E-9 T 05-07-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 K08M4_RS06635 1d37d55a5dc93efcaac16655a77db38e 191 Gene3D G3DSA:1.10.3420.10 12 127 2.7E-17 T 05-07-2017 IPR023292 NTP pyrophosphohydrolase-like domain K08M4_RS06635 1d37d55a5dc93efcaac16655a77db38e 191 Gene3D G3DSA:1.10.3420.10 166 188 2.7E-17 T 05-07-2017 IPR023292 NTP pyrophosphohydrolase-like domain K08M4_RS05365 ee10e5f18c0555e76e899f2eb531874c 106 Gene3D G3DSA:3.30.1390.10 4 105 4.9E-44 T 05-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like K08M4_RS05365 ee10e5f18c0555e76e899f2eb531874c 106 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 8 101 27.73 T 05-07-2017 IPR022935 ATP-dependent Clp protease adaptor protein ClpS K08M4_RS05365 ee10e5f18c0555e76e899f2eb531874c 106 SUPERFAMILY SSF54736 21 105 6.28E-32 T 05-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like K08M4_RS05365 ee10e5f18c0555e76e899f2eb531874c 106 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 23 102 1.5E-33 T 05-07-2017 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 K08M4_RS05665 512c15d687cff620c1c15fb90e906fa9 309 PIRSF PIRSF006278 3 299 1.7E-20 T 05-07-2017 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase K08M4_RS05665 512c15d687cff620c1c15fb90e906fa9 309 Gene3D G3DSA:3.40.50.1100 103 294 1.4E-14 T 05-07-2017 K08M4_RS05665 512c15d687cff620c1c15fb90e906fa9 309 SUPERFAMILY SSF53686 12 295 1.32E-49 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme K08M4_RS07105 9e916a1662d2d1a5a0c8efc6c6bde3d2 156 Pfam PF00583 Acetyltransferase (GNAT) family 49 134 4.0E-8 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS07105 9e916a1662d2d1a5a0c8efc6c6bde3d2 156 SUPERFAMILY SSF55729 2 141 5.13E-19 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS07105 9e916a1662d2d1a5a0c8efc6c6bde3d2 156 Gene3D G3DSA:3.40.630.30 1 151 3.6E-22 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS00750 2bbaf6e02386965294551b3629894675 446 Pfam PF13091 PLD-like domain 252 402 1.5E-26 T 05-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 K08M4_RS00750 2bbaf6e02386965294551b3629894675 446 Gene3D G3DSA:3.30.870.10 244 408 2.2E-19 T 05-07-2017 K08M4_RS00750 2bbaf6e02386965294551b3629894675 446 Gene3D G3DSA:3.30.870.10 19 182 1.1E-14 T 05-07-2017 K08M4_RS00750 2bbaf6e02386965294551b3629894675 446 SUPERFAMILY SSF56024 7 185 9.16E-25 T 05-07-2017 K08M4_RS00750 2bbaf6e02386965294551b3629894675 446 PIRSF PIRSF000850 2 446 6.0E-216 T 05-07-2017 IPR016270 Phospholipase D, phosphatidylserine synthase type GO:0008654|GO:0016780 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|Reactome: R-HSA-1483148 K08M4_RS00750 2bbaf6e02386965294551b3629894675 446 SUPERFAMILY SSF56024 244 421 9.42E-26 T 05-07-2017 K08M4_RS00750 2bbaf6e02386965294551b3629894675 446 SMART SM00155 126 152 0.011 T 05-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 K08M4_RS00750 2bbaf6e02386965294551b3629894675 446 SMART SM00155 347 374 0.0057 T 05-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 K08M4_RS01520 d3a7eb40d3b245050727766e514be726 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 103 3.1E-39 T 05-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01520 d3a7eb40d3b245050727766e514be726 105 Gene3D G3DSA:2.30.30.30 3 92 2.1E-21 T 05-07-2017 IPR014722 Ribosomal protein L2 domain 2 K08M4_RS01520 d3a7eb40d3b245050727766e514be726 105 SUPERFAMILY SSF50104 4 101 2.62E-33 T 05-07-2017 IPR008991 Translation protein SH3-like domain K08M4_RS01520 d3a7eb40d3b245050727766e514be726 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 97 19.692 T 05-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01520 d3a7eb40d3b245050727766e514be726 105 SMART SM00739 4 31 1.8E-4 T 05-07-2017 IPR005824 KOW K08M4_RS01520 d3a7eb40d3b245050727766e514be726 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 8 25 - T 05-07-2017 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01520 d3a7eb40d3b245050727766e514be726 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 39 102 1.2E-23 T 05-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS01520 d3a7eb40d3b245050727766e514be726 105 Pfam PF00467 KOW motif 8 37 2.1E-5 T 05-07-2017 IPR005824 KOW K08M4_RS10605 20506647a7dcc1629d2aba7ca36ef20f 252 Pfam PF08907 Domain of unknown function (DUF1853) 42 215 1.7E-34 T 05-07-2017 IPR015003 Protein of unknown function DUF1853 K08M4_RS21630 6ad7000615979c74b75127ddf654bb79 130 SUPERFAMILY SSF51316 9 129 2.93E-32 T 05-07-2017 IPR011057 Mss4-like K08M4_RS21630 6ad7000615979c74b75127ddf654bb79 130 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 37 113 8.0E-10 T 05-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 K08M4_RS21630 6ad7000615979c74b75127ddf654bb79 130 Gene3D G3DSA:3.90.1590.10 11 111 3.0E-19 T 05-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 K08M4_RS01495 238c2b66de57b4637b65e15f5d93332a 232 SUPERFAMILY SSF54821 108 206 2.09E-40 T 05-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01495 238c2b66de57b4637b65e15f5d93332a 232 SUPERFAMILY SSF54814 2 106 5.23E-36 T 05-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 K08M4_RS01495 238c2b66de57b4637b65e15f5d93332a 232 SMART SM00322 60 125 1.8E-7 T 05-07-2017 IPR004087 K Homology domain GO:0003676 K08M4_RS01495 238c2b66de57b4637b65e15f5d93332a 232 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 2.6E-97 T 05-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 K08M4_RS01495 238c2b66de57b4637b65e15f5d93332a 232 Gene3D G3DSA:3.30.300.20 18 107 1.9E-32 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta K08M4_RS01495 238c2b66de57b4637b65e15f5d93332a 232 Gene3D G3DSA:3.30.1140.32 108 207 1.2E-46 T 05-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01495 238c2b66de57b4637b65e15f5d93332a 232 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 6.5E-41 T 05-07-2017 K08M4_RS01495 238c2b66de57b4637b65e15f5d93332a 232 Pfam PF07650 KH domain 38 111 5.7E-19 T 05-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01495 238c2b66de57b4637b65e15f5d93332a 232 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.675 T 05-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 K08M4_RS01495 238c2b66de57b4637b65e15f5d93332a 232 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 05-07-2017 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS11370 0a09f3fe6324468bebbf705b646e267b 113 SUPERFAMILY SSF141488 32 111 1.44E-12 T 05-07-2017 IPR018660 C-type lysozyme, inhibitor K08M4_RS11370 0a09f3fe6324468bebbf705b646e267b 113 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 37 109 1.4E-15 T 05-07-2017 IPR018660 C-type lysozyme, inhibitor K08M4_RS20520 487dede55628fb2702499c8166cd5e6c 280 Gene3D G3DSA:1.10.3720.10 7 269 7.1E-46 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS20520 487dede55628fb2702499c8166cd5e6c 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 275 7.3E-16 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS20520 487dede55628fb2702499c8166cd5e6c 280 SUPERFAMILY SSF161098 8 277 8.94E-54 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS06310 ea14781901b2a406f340d49a959b1bd4 451 Pfam PF00027 Cyclic nucleotide-binding domain 21 101 6.7E-9 T 05-07-2017 IPR000595 Cyclic nucleotide-binding domain K08M4_RS06310 ea14781901b2a406f340d49a959b1bd4 451 SMART SM00387 335 446 4.3E-21 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS06310 ea14781901b2a406f340d49a959b1bd4 451 Gene3D G3DSA:2.60.120.10 20 101 1.7E-11 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS06310 ea14781901b2a406f340d49a959b1bd4 451 Gene3D G3DSA:3.30.565.10 298 446 1.4E-30 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS06310 ea14781901b2a406f340d49a959b1bd4 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 443 1.8E-10 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS06310 ea14781901b2a406f340d49a959b1bd4 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 388 1.8E-10 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS06310 ea14781901b2a406f340d49a959b1bd4 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 425 1.8E-10 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS06310 ea14781901b2a406f340d49a959b1bd4 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 402 1.8E-10 T 05-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 K08M4_RS06310 ea14781901b2a406f340d49a959b1bd4 451 SUPERFAMILY SSF55874 299 444 2.62E-28 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS06310 ea14781901b2a406f340d49a959b1bd4 451 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 444 9.3E-17 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS06310 ea14781901b2a406f340d49a959b1bd4 451 SUPERFAMILY SSF51206 19 131 4.84E-15 T 05-07-2017 IPR018490 Cyclic nucleotide-binding-like K08M4_RS04410 bf2c24c46d3beae04e0ae8b51c27a968 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 300 1.6E-12 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS04410 bf2c24c46d3beae04e0ae8b51c27a968 312 SUPERFAMILY SSF161098 73 299 7.19E-46 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS04410 bf2c24c46d3beae04e0ae8b51c27a968 312 Gene3D G3DSA:1.10.3720.10 79 304 6.0E-51 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS17950 3b7d1a23e4ca1defbfaeeb216b432bff 621 SMART SM00304 290 344 1.3E-11 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS17950 3b7d1a23e4ca1defbfaeeb216b432bff 621 Pfam PF00672 HAMP domain 274 341 4.6E-13 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS17950 3b7d1a23e4ca1defbfaeeb216b432bff 621 Gene3D G3DSA:1.10.287.950 374 589 3.2E-52 T 05-07-2017 K08M4_RS17950 3b7d1a23e4ca1defbfaeeb216b432bff 621 SUPERFAMILY SSF103190 61 170 3.92E-9 T 05-07-2017 IPR029151 Periplasmic sensor domain-like K08M4_RS17950 3b7d1a23e4ca1defbfaeeb216b432bff 621 Pfam PF02743 Cache domain 31 252 5.9E-28 T 05-07-2017 IPR033479 Double Cache domain 1 K08M4_RS17950 3b7d1a23e4ca1defbfaeeb216b432bff 621 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 425 619 1.2E-46 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS17950 3b7d1a23e4ca1defbfaeeb216b432bff 621 SUPERFAMILY SSF58104 312 621 1.31E-74 T 05-07-2017 K08M4_RS17950 3b7d1a23e4ca1defbfaeeb216b432bff 621 SMART SM00283 359 620 3.6E-63 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS17950 3b7d1a23e4ca1defbfaeeb216b432bff 621 Gene3D G3DSA:3.30.450.20 130 267 8.6E-28 T 05-07-2017 K08M4_RS14010 78b786c9b1478db87e89881998520eee 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 14.62 T 05-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS14010 78b786c9b1478db87e89881998520eee 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 05-07-2017 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS14010 78b786c9b1478db87e89881998520eee 55 Pfam PF00471 Ribosomal protein L33 7 53 1.2E-16 T 05-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS14010 78b786c9b1478db87e89881998520eee 55 SUPERFAMILY SSF57829 1 53 4.7E-19 T 05-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 K08M4_RS14010 78b786c9b1478db87e89881998520eee 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 3.6E-25 T 05-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS16475 51381b51a32f8e9285358ad1fa3339c3 329 SUPERFAMILY SSF56935 22 329 1.1E-42 T 05-07-2017 K08M4_RS16475 51381b51a32f8e9285358ad1fa3339c3 329 Gene3D G3DSA:2.40.160.10 22 329 1.3E-43 T 05-07-2017 IPR023614 Porin domain K08M4_RS16475 51381b51a32f8e9285358ad1fa3339c3 329 Pfam PF13609 Gram-negative porin 8 300 2.7E-17 T 05-07-2017 K08M4_RS01720 e8c7e001f081ea10ee756dc527a6d817 66 Pfam PF06526 Protein of unknown function (DUF1107) 2 64 3.2E-24 T 05-07-2017 IPR009491 Protein of unknown function DUF1107 K08M4_RS01720 e8c7e001f081ea10ee756dc527a6d817 66 Gene3D G3DSA:3.30.1910.10 2 65 2.8E-27 T 05-07-2017 K08M4_RS01720 e8c7e001f081ea10ee756dc527a6d817 66 ProDom PD055267 YTFK Y0656 CYTOPLASMIC VP2585 VV0426 ESCHERICHIA S4534 VC2473 YPO3527 COLI 1 64 1.0E-19 T 05-07-2017 IPR009491 Protein of unknown function DUF1107 K08M4_RS01505 f0769fc9ef2608867721115b8d1ba21e 63 Pfam PF00831 Ribosomal L29 protein 4 60 9.8E-25 T 05-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01505 f0769fc9ef2608867721115b8d1ba21e 63 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 05-07-2017 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01505 f0769fc9ef2608867721115b8d1ba21e 63 Gene3D G3DSA:1.10.287.310 1 60 2.4E-29 T 05-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01505 f0769fc9ef2608867721115b8d1ba21e 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 19.082 T 05-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01505 f0769fc9ef2608867721115b8d1ba21e 63 SUPERFAMILY SSF46561 1 61 4.58E-23 T 05-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS01505 f0769fc9ef2608867721115b8d1ba21e 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 2.4E-23 T 05-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 K08M4_RS17825 d54ace070672adb29db5b612fa2c45b8 192 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 15 185 2.9E-68 T 05-07-2017 IPR005126 NapC/NirT cytochrome c, N-terminal K08M4_RS17825 d54ace070672adb29db5b612fa2c45b8 192 PIRSF PIRSF000013 1 192 1.7E-91 T 05-07-2017 IPR024717 Denitrification system component NapC/NirT/NrfH GO:0016021|GO:0019333|GO:0020037 K08M4_RS17825 d54ace070672adb29db5b612fa2c45b8 192 Gene3D G3DSA:1.10.3820.10 16 184 5.7E-24 T 05-07-2017 K08M4_RS17825 d54ace070672adb29db5b612fa2c45b8 192 SUPERFAMILY SSF48695 18 191 3.01E-54 T 05-07-2017 IPR011031 Multihaem cytochrome K08M4_RS18885 b6629fa045d1de42549d146c1a451efe 203 PIRSF PIRSF011489 1 196 3.6E-73 T 05-07-2017 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 K08M4_RS18885 b6629fa045d1de42549d146c1a451efe 203 Pfam PF04336 Protein of unknown function, DUF479 81 185 1.0E-28 T 05-07-2017 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 K08M4_RS16410 6e3e1ef4d6862f6750b575fa4ffd15cd 139 Gene3D G3DSA:3.90.1590.10 8 138 1.9E-28 T 05-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 K08M4_RS16410 6e3e1ef4d6862f6750b575fa4ffd15cd 139 SUPERFAMILY SSF51316 11 138 2.09E-32 T 05-07-2017 IPR011057 Mss4-like K08M4_RS16410 6e3e1ef4d6862f6750b575fa4ffd15cd 139 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 34 122 3.6E-20 T 05-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 K08M4_RS13165 c089cee67600305541d2fc0738c9b075 384 Gene3D G3DSA:1.25.40.10 297 354 1.3E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS13165 c089cee67600305541d2fc0738c9b075 384 Gene3D G3DSA:1.25.40.10 198 282 8.6E-11 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS13165 c089cee67600305541d2fc0738c9b075 384 SUPERFAMILY SSF48452 199 354 7.46E-15 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS04420 3650eb10d6041010d71448d1895988ba 370 SUPERFAMILY SSF52540 4 246 1.11E-86 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04420 3650eb10d6041010d71448d1895988ba 370 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS04420 3650eb10d6041010d71448d1895988ba 370 Pfam PF00005 ABC transporter 21 163 2.5E-32 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS04420 3650eb10d6041010d71448d1895988ba 370 SUPERFAMILY SSF50331 238 368 1.92E-23 T 05-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal K08M4_RS04420 3650eb10d6041010d71448d1895988ba 370 Gene3D G3DSA:2.40.50.140 291 353 5.8E-12 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS04420 3650eb10d6041010d71448d1895988ba 370 SMART SM00382 30 213 1.0E-17 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS04420 3650eb10d6041010d71448d1895988ba 370 Gene3D G3DSA:2.40.50.100 354 368 2.6E-9 T 05-07-2017 K08M4_RS04420 3650eb10d6041010d71448d1895988ba 370 Gene3D G3DSA:2.40.50.100 241 290 2.6E-9 T 05-07-2017 K08M4_RS04420 3650eb10d6041010d71448d1895988ba 370 Gene3D G3DSA:3.40.50.300 3 236 3.1E-81 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12335 71db646f6b8783ac72d1612fa2986f1b 578 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 20 574 8.1E-157 T 05-07-2017 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 K08M4_RS12335 71db646f6b8783ac72d1612fa2986f1b 578 SUPERFAMILY SSF64182 45 462 4.45E-117 T 05-07-2017 K08M4_RS12335 71db646f6b8783ac72d1612fa2986f1b 578 Pfam PF01368 DHH family 71 204 2.9E-10 T 05-07-2017 IPR001667 DDH domain K08M4_RS12335 71db646f6b8783ac72d1612fa2986f1b 578 Pfam PF02272 DHHA1 domain 379 447 1.1E-14 T 05-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 K08M4_RS18660 f95ca46c42295a0379353bd755c96c47 202 Pfam PF09997 Predicted membrane protein (DUF2238) 46 181 1.8E-52 T 05-07-2017 IPR014509 Uncharacterised conserved protein UCP020606 K08M4_RS18660 f95ca46c42295a0379353bd755c96c47 202 PIRSF PIRSF020606 5 202 2.0E-80 T 05-07-2017 IPR014509 Uncharacterised conserved protein UCP020606 K08M4_RS18880 9234aa24dddc48ef831d68eee167db0c 423 SMART SM00487 25 229 2.0E-59 T 05-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain K08M4_RS18880 9234aa24dddc48ef831d68eee167db0c 423 Gene3D G3DSA:3.40.50.300 3 218 2.8E-82 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18880 9234aa24dddc48ef831d68eee167db0c 423 Pfam PF00271 Helicase conserved C-terminal domain 240 346 3.3E-28 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS18880 9234aa24dddc48ef831d68eee167db0c 423 SUPERFAMILY SSF52540 83 364 3.56E-75 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18880 9234aa24dddc48ef831d68eee167db0c 423 Gene3D G3DSA:3.40.50.300 219 377 3.1E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18880 9234aa24dddc48ef831d68eee167db0c 423 SMART SM00490 265 346 6.4E-32 T 05-07-2017 IPR001650 Helicase, C-terminal K08M4_RS18880 9234aa24dddc48ef831d68eee167db0c 423 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 160 168 - T 05-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site K08M4_RS18880 9234aa24dddc48ef831d68eee167db0c 423 Pfam PF00270 DEAD/DEAH box helicase 30 202 4.5E-52 T 05-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 K08M4_RS08635 2303d1f9c90ceccd1278a6ac11ecdc6b 301 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 134 299 5.0E-72 T 05-07-2017 IPR005642 Lysine exporter LysO K08M4_RS08635 2303d1f9c90ceccd1278a6ac11ecdc6b 301 Pfam PF03956 Membrane protein of unknown function (DUF340) 112 297 3.9E-53 T 05-07-2017 IPR005642 Lysine exporter LysO K08M4_RS21560 d8c5e377ac401f15e77913d7ec578f2f 315 PIRSF PIRSF037004 1 315 1.0E-121 T 05-07-2017 IPR017087 Uncharacterised conserved protein UCP037004 K08M4_RS21560 d8c5e377ac401f15e77913d7ec578f2f 315 Pfam PF08349 Protein of unknown function (DUF1722) 191 306 4.2E-41 T 05-07-2017 IPR013560 Domain of unknown function DUF1722 K08M4_RS21560 d8c5e377ac401f15e77913d7ec578f2f 315 Pfam PF04463 Protein of unknown function (DUF523) 7 147 2.9E-33 T 05-07-2017 IPR007553 Domain of unknown function DUF523 K08M4_RS10720 74775b81ad78a1a8e6a6b62502d50337 135 Gene3D G3DSA:3.10.580.10 8 126 1.2E-23 T 05-07-2017 K08M4_RS10720 74775b81ad78a1a8e6a6b62502d50337 135 SMART SM00116 83 130 2.9E-4 T 05-07-2017 IPR000644 CBS domain K08M4_RS10720 74775b81ad78a1a8e6a6b62502d50337 135 SMART SM00116 16 65 8.3 T 05-07-2017 IPR000644 CBS domain K08M4_RS10720 74775b81ad78a1a8e6a6b62502d50337 135 Pfam PF00571 CBS domain 9 64 0.0018 T 05-07-2017 IPR000644 CBS domain K08M4_RS10720 74775b81ad78a1a8e6a6b62502d50337 135 Pfam PF00571 CBS domain 76 125 8.9E-9 T 05-07-2017 IPR000644 CBS domain K08M4_RS10720 74775b81ad78a1a8e6a6b62502d50337 135 SUPERFAMILY SSF54631 4 126 1.06E-25 T 05-07-2017 K08M4_RS21105 db7c146573e4d4e4010bbaa29d169c08 442 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 6 440 7.3E-146 T 05-07-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 K08M4_RS21105 db7c146573e4d4e4010bbaa29d169c08 442 PIRSF PIRSF004539 1 441 3.9E-183 T 05-07-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 K08M4_RS21105 db7c146573e4d4e4010bbaa29d169c08 442 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 5 373 8.0E-151 T 05-07-2017 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 K08M4_RS14150 c9a509287aed1acc6b47ddca89a844e5 239 SMART SM00448 5 116 1.0E-44 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS14150 c9a509287aed1acc6b47ddca89a844e5 239 Gene3D G3DSA:1.10.10.10 133 235 1.7E-31 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS14150 c9a509287aed1acc6b47ddca89a844e5 239 SUPERFAMILY SSF46894 132 234 9.92E-26 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS14150 c9a509287aed1acc6b47ddca89a844e5 239 Gene3D G3DSA:3.40.50.2300 4 125 2.7E-41 T 05-07-2017 K08M4_RS14150 c9a509287aed1acc6b47ddca89a844e5 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 232 1.5E-21 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS14150 c9a509287aed1acc6b47ddca89a844e5 239 SMART SM00862 156 232 8.9E-20 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS14150 c9a509287aed1acc6b47ddca89a844e5 239 Pfam PF00072 Response regulator receiver domain 7 117 1.4E-29 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS14150 c9a509287aed1acc6b47ddca89a844e5 239 SUPERFAMILY SSF52172 3 127 1.85E-41 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS00185 89b54bf1a6b55b18148758f4b7cdcc30 375 SUPERFAMILY SSF102114 37 366 2.09E-53 T 05-07-2017 K08M4_RS00185 89b54bf1a6b55b18148758f4b7cdcc30 375 TIGRFAM TIGR02351 thiH: thiazole biosynthesis protein ThiH 2 371 1.3E-177 T 05-07-2017 IPR012726 Thiazole biosynthesis ThiH GO:0005506|GO:0009228|GO:0051539 KEGG: 00730+4.1.99.19|MetaCyc: PWY-6892 K08M4_RS00185 89b54bf1a6b55b18148758f4b7cdcc30 375 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 256 362 1.9E-26 T 05-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 K08M4_RS00185 89b54bf1a6b55b18148758f4b7cdcc30 375 Gene3D G3DSA:3.20.20.70 37 366 3.4E-46 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS00185 89b54bf1a6b55b18148758f4b7cdcc30 375 SMART SM00876 256 364 9.2E-38 T 05-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 K08M4_RS00185 89b54bf1a6b55b18148758f4b7cdcc30 375 Pfam PF04055 Radical SAM superfamily 81 221 2.6E-9 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS15505 e00f23e77cfb3dbd0b738702c4256739 210 SUPERFAMILY SSF102114 18 201 2.62E-27 T 05-07-2017 K08M4_RS15505 e00f23e77cfb3dbd0b738702c4256739 210 Pfam PF04055 Radical SAM superfamily 19 183 3.1E-12 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS15505 e00f23e77cfb3dbd0b738702c4256739 210 Gene3D G3DSA:3.20.20.70 5 200 3.6E-26 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS15505 e00f23e77cfb3dbd0b738702c4256739 210 Pfam PF13353 4Fe-4S single cluster domain 17 131 1.5E-6 T 05-07-2017 K08M4_RS09570 4a06ce1e2c42645ae8dbd550a00d7799 162 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 39 51 1.2E-10 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS09570 4a06ce1e2c42645ae8dbd550a00d7799 162 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 13 28 1.2E-10 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS09570 4a06ce1e2c42645ae8dbd550a00d7799 162 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 116 131 1.2E-10 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS09570 4a06ce1e2c42645ae8dbd550a00d7799 162 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 34 51 - T 05-07-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 K08M4_RS09570 4a06ce1e2c42645ae8dbd550a00d7799 162 SUPERFAMILY SSF50891 5 160 5.99E-55 T 05-07-2017 IPR029000 Cyclophilin-like domain K08M4_RS09570 4a06ce1e2c42645ae8dbd550a00d7799 162 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 6 157 1.5E-45 T 05-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 K08M4_RS09570 4a06ce1e2c42645ae8dbd550a00d7799 162 PIRSF PIRSF001467 1 161 1.5E-26 T 05-07-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 K08M4_RS09570 4a06ce1e2c42645ae8dbd550a00d7799 162 Gene3D G3DSA:2.40.100.10 5 160 5.0E-50 T 05-07-2017 IPR029000 Cyclophilin-like domain K08M4_RS04995 f0697561768fbf3c1309ac65018e7d04 150 Hamap MF_01101 UPF0208 membrane protein YfbV [yfbV]. 5 150 35.545 T 05-07-2017 IPR007334 Uncharacterised protein family UPF0208 K08M4_RS04995 f0697561768fbf3c1309ac65018e7d04 150 Pfam PF04217 Protein of unknown function, DUF412 9 146 1.8E-58 T 05-07-2017 IPR007334 Uncharacterised protein family UPF0208 K08M4_RS07130 7f8a0c1ce6483230b348c34730a83a3d 110 Gene3D G3DSA:3.10.450.50 30 109 6.4E-13 T 05-07-2017 IPR032710 NTF2-like domain K08M4_RS07130 7f8a0c1ce6483230b348c34730a83a3d 110 TIGRFAM TIGR04102 SWIM_PBPRA1643: SWIM/SEC-C metal-binding motif protein, PBPRA1643 family 3 110 1.5E-47 T 05-07-2017 IPR026368 SWIM/SEC-C metal-binding motif protein, PBPRA1643 family K08M4_RS07130 7f8a0c1ce6483230b348c34730a83a3d 110 Pfam PF02810 SEC-C motif 93 110 6.5E-9 T 05-07-2017 IPR004027 SEC-C motif K08M4_RS07130 7f8a0c1ce6483230b348c34730a83a3d 110 SUPERFAMILY SSF103642 91 109 3.27E-7 T 05-07-2017 K08M4_RS16355 f6dc1870691a28049cc302e5df7daa26 233 Pfam PF01618 MotA/TolQ/ExbB proton channel family 96 194 5.0E-21 T 05-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 K08M4_RS15450 231ac7e94b636afc47fbcfb0b0fbf8b5 332 SUPERFAMILY SSF53822 62 329 3.44E-65 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS15450 231ac7e94b636afc47fbcfb0b0fbf8b5 332 Pfam PF13377 Periplasmic binding protein-like domain 171 327 1.3E-32 T 05-07-2017 K08M4_RS15450 231ac7e94b636afc47fbcfb0b0fbf8b5 332 SUPERFAMILY SSF47413 1 60 1.1E-18 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS15450 231ac7e94b636afc47fbcfb0b0fbf8b5 332 SMART SM00354 1 71 8.6E-27 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS15450 231ac7e94b636afc47fbcfb0b0fbf8b5 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 1.6E-5 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS15450 231ac7e94b636afc47fbcfb0b0fbf8b5 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 1.6E-5 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS15450 231ac7e94b636afc47fbcfb0b0fbf8b5 332 Gene3D G3DSA:1.10.260.40 2 57 1.6E-24 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS15450 231ac7e94b636afc47fbcfb0b0fbf8b5 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 05-07-2017 K08M4_RS15450 231ac7e94b636afc47fbcfb0b0fbf8b5 332 Gene3D G3DSA:3.40.50.2300 170 329 5.8E-49 T 05-07-2017 K08M4_RS15450 231ac7e94b636afc47fbcfb0b0fbf8b5 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.2E-17 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS15450 231ac7e94b636afc47fbcfb0b0fbf8b5 332 Gene3D G3DSA:3.40.50.2300 58 169 1.3E-33 T 05-07-2017 K08M4_RS16765 4e9db03ec8847a78db9ec9a9e92d8ce9 117 SUPERFAMILY SSF47413 6 81 6.88E-15 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS16765 4e9db03ec8847a78db9ec9a9e92d8ce9 117 Gene3D G3DSA:1.10.260.40 4 76 2.1E-14 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS02990 c9d2f99a0c6e18b9e2e8af5572bdcfca 341 SUPERFAMILY SSF161098 96 287 4.19E-19 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS02990 c9d2f99a0c6e18b9e2e8af5572bdcfca 341 Gene3D G3DSA:1.10.3720.10 93 296 1.8E-19 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS02990 c9d2f99a0c6e18b9e2e8af5572bdcfca 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 306 9.2E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS02990 c9d2f99a0c6e18b9e2e8af5572bdcfca 341 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 2 38 1.7E-5 T 05-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain K08M4_RS12965 b1557aa6f15e87a10d53be5d4a66b4d9 329 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 32 321 1.1E-105 T 05-07-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 K08M4_RS12965 b1557aa6f15e87a10d53be5d4a66b4d9 329 Gene3D G3DSA:3.40.718.10 2 328 2.2E-131 T 05-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 K08M4_RS12965 b1557aa6f15e87a10d53be5d4a66b4d9 329 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 5 324 1.7E-126 T 05-07-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 K08M4_RS12965 b1557aa6f15e87a10d53be5d4a66b4d9 329 SUPERFAMILY SSF53659 3 327 1.2E-111 T 05-07-2017 K08M4_RS12965 b1557aa6f15e87a10d53be5d4a66b4d9 329 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 2 325 35.424 T 05-07-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 K08M4_RS21365 994d71df47250ceb225ab4cf355abd15 971 Gene3D G3DSA:3.40.720.10 390 651 9.4E-7 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 K08M4_RS21365 994d71df47250ceb225ab4cf355abd15 971 SUPERFAMILY SSF53649 387 494 1.62E-9 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 K08M4_RS21365 994d71df47250ceb225ab4cf355abd15 971 SUPERFAMILY SSF53649 542 658 1.62E-9 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 K08M4_RS21365 994d71df47250ceb225ab4cf355abd15 971 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 387 652 6.2E-10 T 05-07-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 K08M4_RS00915 6833aa6b372624b23faa1779fbf42806 295 PIRSF PIRSF000401 1 295 4.7E-97 T 05-07-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 K08M4_RS00915 6833aa6b372624b23faa1779fbf42806 295 SUPERFAMILY SSF53335 45 274 7.08E-45 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS00915 6833aa6b372624b23faa1779fbf42806 295 Gene3D G3DSA:3.40.50.150 99 287 2.5E-42 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS00915 6833aa6b372624b23faa1779fbf42806 295 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 287 3.2E-107 T 05-07-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 K08M4_RS00915 6833aa6b372624b23faa1779fbf42806 295 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 293 33.205 T 05-07-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 K08M4_RS00915 6833aa6b372624b23faa1779fbf42806 295 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 293 4.0E-103 T 05-07-2017 K08M4_RS02060 fed5275cd64e2eb64be1cc6e9eb87919 541 Gene3D G3DSA:3.30.450.20 18 178 1.5E-32 T 05-07-2017 K08M4_RS02060 fed5275cd64e2eb64be1cc6e9eb87919 541 Gene3D G3DSA:1.10.287.950 292 508 7.6E-56 T 05-07-2017 K08M4_RS02060 fed5275cd64e2eb64be1cc6e9eb87919 541 SMART SM01049 30 124 2.3E-18 T 05-07-2017 IPR033480 Single Cache domain 2 K08M4_RS02060 fed5275cd64e2eb64be1cc6e9eb87919 541 SMART SM00283 277 538 1.5E-69 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS02060 fed5275cd64e2eb64be1cc6e9eb87919 541 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 404 433 6.1E-26 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS02060 fed5275cd64e2eb64be1cc6e9eb87919 541 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 375 402 6.1E-26 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS02060 fed5275cd64e2eb64be1cc6e9eb87919 541 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 3 28 6.1E-26 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS02060 fed5275cd64e2eb64be1cc6e9eb87919 541 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 184 204 6.1E-26 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS02060 fed5275cd64e2eb64be1cc6e9eb87919 541 SUPERFAMILY SSF58104 236 539 2.88E-70 T 05-07-2017 K08M4_RS02060 fed5275cd64e2eb64be1cc6e9eb87919 541 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 345 537 1.4E-47 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS02060 fed5275cd64e2eb64be1cc6e9eb87919 541 Pfam PF17200 Single Cache domain 2 37 185 2.2E-34 T 05-07-2017 IPR033480 Single Cache domain 2 K08M4_RS03320 a3eb966484dfb7d39cce0f398445857c 460 SMART SM00327 140 428 2.2E-4 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS03320 a3eb966484dfb7d39cce0f398445857c 460 SUPERFAMILY SSF53300 132 261 7.66E-19 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS03320 a3eb966484dfb7d39cce0f398445857c 460 SUPERFAMILY SSF53300 367 414 7.66E-19 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS03320 a3eb966484dfb7d39cce0f398445857c 460 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 16 61 6.1E-8 T 05-07-2017 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal K08M4_RS03320 a3eb966484dfb7d39cce0f398445857c 460 Gene3D G3DSA:3.40.50.410 139 264 1.4E-15 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS03320 a3eb966484dfb7d39cce0f398445857c 460 Gene3D G3DSA:3.40.50.410 366 391 1.4E-15 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS03320 a3eb966484dfb7d39cce0f398445857c 460 Pfam PF00092 von Willebrand factor type A domain 142 261 5.9E-9 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS11395 48aa87eebaf963e0d8a6b7266cb5f0b3 258 Pfam PF10071 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) 1 256 2.8E-111 T 05-07-2017 IPR016908 Uncharacterised conserved protein UCP029037 K08M4_RS11395 48aa87eebaf963e0d8a6b7266cb5f0b3 258 PIRSF PIRSF029037 1 258 2.8E-111 T 05-07-2017 IPR016908 Uncharacterised conserved protein UCP029037 K08M4_RS02175 160bba1c17ca20ad9d097f5e143c14dd 187 Gene3D G3DSA:3.30.70.1300 42 130 9.3E-29 T 05-07-2017 K08M4_RS02175 160bba1c17ca20ad9d097f5e143c14dd 187 Pfam PF02622 Uncharacterized ACR, COG1678 12 174 9.8E-51 T 05-07-2017 IPR003774 Protein of unknown function UPF0301 K08M4_RS02175 160bba1c17ca20ad9d097f5e143c14dd 187 SUPERFAMILY SSF143456 1 187 2.35E-65 T 05-07-2017 K08M4_RS02175 160bba1c17ca20ad9d097f5e143c14dd 187 Gene3D G3DSA:3.40.1740.10 2 40 5.5E-37 T 05-07-2017 K08M4_RS02175 160bba1c17ca20ad9d097f5e143c14dd 187 Gene3D G3DSA:3.40.1740.10 131 178 5.5E-37 T 05-07-2017 K08M4_RS02175 160bba1c17ca20ad9d097f5e143c14dd 187 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 1 187 39.126 T 05-07-2017 IPR003774 Protein of unknown function UPF0301 K08M4_RS20440 04e51a094009bb81ea524c5adbd416d4 175 Pfam PF16105 Domain of unknown function (DUF4823) 33 173 4.5E-55 T 05-07-2017 IPR032248 Protein of unknown function DUF4823 K08M4_RS04800 2dd95a159ab32c10f69269fc71631133 901 Gene3D G3DSA:3.40.309.10 226 273 6.0E-27 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 K08M4_RS04800 2dd95a159ab32c10f69269fc71631133 901 Gene3D G3DSA:3.40.309.10 309 405 6.0E-27 T 05-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 K08M4_RS04800 2dd95a159ab32c10f69269fc71631133 901 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 631 659 - T 05-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 K08M4_RS04800 2dd95a159ab32c10f69269fc71631133 901 Gene3D G3DSA:1.20.1090.10 643 861 1.1E-67 T 05-07-2017 K08M4_RS04800 2dd95a159ab32c10f69269fc71631133 901 Gene3D G3DSA:3.40.50.1970 451 642 9.5E-61 T 05-07-2017 K08M4_RS04800 2dd95a159ab32c10f69269fc71631133 901 Gene3D G3DSA:3.40.605.10 2 225 1.7E-22 T 05-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS04800 2dd95a159ab32c10f69269fc71631133 901 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 719 739 - T 05-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 K08M4_RS04800 2dd95a159ab32c10f69269fc71631133 901 SUPERFAMILY SSF56796 452 863 3.14E-115 T 05-07-2017 K08M4_RS04800 2dd95a159ab32c10f69269fc71631133 901 PIRSF PIRSF000111 1 865 0.0 T 05-07-2017 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00592+1.1.1.1|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00650+1.2.1.10|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7085|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7180|MetaCyc: PWY-7396 K08M4_RS04800 2dd95a159ab32c10f69269fc71631133 901 Pfam PF00171 Aldehyde dehydrogenase family 5 402 8.3E-24 T 05-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 K08M4_RS04800 2dd95a159ab32c10f69269fc71631133 901 Pfam PF00465 Iron-containing alcohol dehydrogenase 458 848 1.2E-113 T 05-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 K08M4_RS04800 2dd95a159ab32c10f69269fc71631133 901 SUPERFAMILY SSF53720 6 454 5.89E-82 T 05-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 K08M4_RS03400 38f5ebb876a8e3fdab0da102b5dfd7ad 334 Gene3D G3DSA:1.25.40.10 52 320 4.5E-43 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS03400 38f5ebb876a8e3fdab0da102b5dfd7ad 334 Pfam PF13374 Tetratricopeptide repeat 283 309 0.0017 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS03400 38f5ebb876a8e3fdab0da102b5dfd7ad 334 SMART SM00028 183 216 12.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS03400 38f5ebb876a8e3fdab0da102b5dfd7ad 334 SMART SM00028 87 120 0.06 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS03400 38f5ebb876a8e3fdab0da102b5dfd7ad 334 SMART SM00028 217 250 5.3E-6 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS03400 38f5ebb876a8e3fdab0da102b5dfd7ad 334 SMART SM00028 121 154 38.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS03400 38f5ebb876a8e3fdab0da102b5dfd7ad 334 SMART SM00028 281 314 8.7E-4 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS03400 38f5ebb876a8e3fdab0da102b5dfd7ad 334 Pfam PF14559 Tetratricopeptide repeat 230 274 3.2E-7 T 05-07-2017 K08M4_RS03400 38f5ebb876a8e3fdab0da102b5dfd7ad 334 Pfam PF13432 Tetratricopeptide repeat 93 147 8.1E-5 T 05-07-2017 K08M4_RS03400 38f5ebb876a8e3fdab0da102b5dfd7ad 334 SUPERFAMILY SSF48452 57 319 1.42E-28 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS09250 4d4783330c8bf70595c10ee9dbb10a50 483 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 68 86 - T 05-07-2017 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 K08M4_RS09250 4d4783330c8bf70595c10ee9dbb10a50 483 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 276 483 31.152 T 05-07-2017 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 K08M4_RS09250 4d4783330c8bf70595c10ee9dbb10a50 483 SUPERFAMILY SSF51366 29 274 5.42E-79 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 K08M4_RS09250 4d4783330c8bf70595c10ee9dbb10a50 483 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 21 275 34.682 T 05-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 K08M4_RS09250 4d4783330c8bf70595c10ee9dbb10a50 483 SUPERFAMILY SSF51366 278 481 2.35E-52 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 K08M4_RS09250 4d4783330c8bf70595c10ee9dbb10a50 483 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 278 477 8.4E-53 T 05-07-2017 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 K08M4_RS09250 4d4783330c8bf70595c10ee9dbb10a50 483 Gene3D G3DSA:3.20.20.70 281 482 3.4E-61 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS09250 4d4783330c8bf70595c10ee9dbb10a50 483 Gene3D G3DSA:3.20.20.70 19 280 3.9E-97 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS09250 4d4783330c8bf70595c10ee9dbb10a50 483 Pfam PF00218 Indole-3-glycerol phosphate synthase 23 272 8.5E-94 T 05-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 K08M4_RS05095 069e5ba32c527ca0fc7e0feaa23e0192 175 Pfam PF02620 Uncharacterized ACR, COG1399 62 174 4.1E-18 T 05-07-2017 IPR003772 Protein of unknown function DUF177 K08M4_RS21115 92bcae2687df78e0186f57bcad12f9db 208 Pfam PF01966 HD domain 25 127 1.2E-9 T 05-07-2017 IPR006674 HD domain K08M4_RS21115 92bcae2687df78e0186f57bcad12f9db 208 SUPERFAMILY SSF109604 7 208 8.17E-61 T 05-07-2017 K08M4_RS21115 92bcae2687df78e0186f57bcad12f9db 208 Gene3D G3DSA:1.10.3210.10 180 208 1.9E-41 T 05-07-2017 IPR006674 HD domain K08M4_RS21115 92bcae2687df78e0186f57bcad12f9db 208 Gene3D G3DSA:1.10.3210.10 8 141 1.9E-41 T 05-07-2017 IPR006674 HD domain K08M4_RS21115 92bcae2687df78e0186f57bcad12f9db 208 SMART SM00471 20 137 4.8E-7 T 05-07-2017 IPR003607 HD/PDEase domain K08M4_RS19125 dd1a3c998b077ebd797b315a976a8e7f 529 Gene3D G3DSA:3.40.50.2300 8 139 3.5E-19 T 05-07-2017 K08M4_RS19125 dd1a3c998b077ebd797b315a976a8e7f 529 Pfam PF00072 Response regulator receiver domain 11 127 4.5E-14 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS19125 dd1a3c998b077ebd797b315a976a8e7f 529 SMART SM00448 9 127 1.7E-10 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS19125 dd1a3c998b077ebd797b315a976a8e7f 529 SUPERFAMILY SSF52172 7 148 1.24E-21 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS20515 506a9495c2743a3f2b6e63339d7a5ee5 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 136 292 4.8E-13 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS20515 506a9495c2743a3f2b6e63339d7a5ee5 293 Gene3D G3DSA:1.10.3720.10 61 290 3.3E-40 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS20515 506a9495c2743a3f2b6e63339d7a5ee5 293 SUPERFAMILY SSF161098 55 282 1.05E-40 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS11425 5a82611646bf1a3ecbc551ed1977c77e 257 Gene3D G3DSA:3.40.50.1010 4 179 2.0E-47 T 05-07-2017 IPR029060 PIN domain-like K08M4_RS11425 5a82611646bf1a3ecbc551ed1977c77e 257 SUPERFAMILY SSF47807 164 254 1.12E-18 T 05-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 K08M4_RS11425 5a82611646bf1a3ecbc551ed1977c77e 257 SUPERFAMILY SSF88723 4 164 2.01E-38 T 05-07-2017 IPR029060 PIN domain-like K08M4_RS11425 5a82611646bf1a3ecbc551ed1977c77e 257 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 156 1.1E-30 T 05-07-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 K08M4_RS11425 5a82611646bf1a3ecbc551ed1977c77e 257 SMART SM00279 167 202 1.4E-7 T 05-07-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 K08M4_RS11425 5a82611646bf1a3ecbc551ed1977c77e 257 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 165 255 6.1E-21 T 05-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 K08M4_RS11425 5a82611646bf1a3ecbc551ed1977c77e 257 Gene3D G3DSA:1.10.150.20 180 238 2.3E-16 T 05-07-2017 K08M4_RS11425 5a82611646bf1a3ecbc551ed1977c77e 257 SMART SM00475 3 254 1.0E-56 T 05-07-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 K08M4_RS11425 5a82611646bf1a3ecbc551ed1977c77e 257 Hamap MF_01192 Flap endonuclease Xni [xni]. 2 255 44.938 T 05-07-2017 IPR022895 Flap endonuclease Xni GO:0048256 K08M4_RS04345 2b422fc3ef44fa917718660191340626 242 Pfam PF11859 Protein of unknown function (DUF3379) 1 238 1.3E-84 T 05-07-2017 IPR021806 Protein of unknown function DUF3379 K08M4_RS17550 a6993535d9864a02331d143ba99df763 387 Pfam PF06738 Putative threonine/serine exporter 97 230 1.3E-13 T 05-07-2017 IPR010619 Putative threonine/serine exporter K08M4_RS17550 a6993535d9864a02331d143ba99df763 387 Pfam PF12821 Threonine/Serine exporter, ThrE 258 377 1.2E-8 T 05-07-2017 IPR024528 Threonine/Serine exporter, ThrE K08M4_RS17820 6129ac9585f0e3809e3cdce493969488 45 TIGRFAM TIGR02808 short_TIGR02808: TIGR02808 family protein 1 42 4.6E-25 T 05-07-2017 IPR014175 Conserved hypothetical protein CHP02808 K08M4_RS17820 6129ac9585f0e3809e3cdce493969488 45 Pfam PF09574 Protein of unknown function (Duf2374) 1 42 4.2E-26 T 05-07-2017 IPR014175 Conserved hypothetical protein CHP02808 K08M4_RS10855 4c74025b0e326603e9ed3b8308cc5fb3 151 SUPERFAMILY SSF141322 88 147 1.7E-6 T 05-07-2017 K08M4_RS10855 4c74025b0e326603e9ed3b8308cc5fb3 151 Pfam PF01957 NfeD-like C-terminal, partner-binding 12 149 1.6E-24 T 05-07-2017 IPR002810 NfeD-like, C-terminal domain K08M4_RS10855 4c74025b0e326603e9ed3b8308cc5fb3 151 Gene3D G3DSA:2.40.50.140 93 148 1.3E-15 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS12500 7aff5179de7845c42e7bd1240ee9aeac 205 Pfam PF03458 UPF0126 domain 95 165 4.0E-19 T 05-07-2017 IPR005115 Uncharacterised domain UPF0126 K08M4_RS12500 7aff5179de7845c42e7bd1240ee9aeac 205 Pfam PF03458 UPF0126 domain 8 81 1.3E-21 T 05-07-2017 IPR005115 Uncharacterised domain UPF0126 K08M4_RS08280 702931722e08dc9434a5051d88b5b956 327 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 326 48.966 T 05-07-2017 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 K08M4_RS08280 702931722e08dc9434a5051d88b5b956 327 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 87 8.2E-26 T 05-07-2017 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 K08M4_RS08280 702931722e08dc9434a5051d88b5b956 327 Gene3D G3DSA:3.30.930.10 10 327 1.6E-132 T 05-07-2017 K08M4_RS08280 702931722e08dc9434a5051d88b5b956 327 Pfam PF01409 tRNA synthetases class II core domain (F) 92 326 6.7E-106 T 05-07-2017 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 K08M4_RS08280 702931722e08dc9434a5051d88b5b956 327 SUPERFAMILY SSF46589 14 99 5.23E-22 T 05-07-2017 IPR010978 tRNA-binding arm GO:0000166 K08M4_RS08280 702931722e08dc9434a5051d88b5b956 327 SUPERFAMILY SSF55681 92 327 7.63E-81 T 05-07-2017 K08M4_RS08280 702931722e08dc9434a5051d88b5b956 327 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 39 327 1.8E-110 T 05-07-2017 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 K08M4_RS14115 7eeaf82e72029cc20c4b636fde9a8476 141 Pfam PF06146 Phosphate-starvation-inducible E 51 117 3.8E-14 T 05-07-2017 IPR020948 Phosphate-starvation-induced PsiE-like K08M4_RS14115 7eeaf82e72029cc20c4b636fde9a8476 141 PIRSF PIRSF029598 3 135 4.2E-38 T 05-07-2017 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 K08M4_RS17625 d9339a63338fbac33c7de3230fb9fc15 120 Pfam PF01042 Endoribonuclease L-PSP 33 114 2.3E-17 T 05-07-2017 IPR006175 YjgF/YER057c/UK114 family K08M4_RS17625 d9339a63338fbac33c7de3230fb9fc15 120 SUPERFAMILY SSF55298 3 115 1.27E-23 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS17625 d9339a63338fbac33c7de3230fb9fc15 120 Gene3D G3DSA:3.30.1330.40 11 116 1.5E-18 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS02840 64933bad18605c97253b04bb609f7610 201 SUPERFAMILY SSF48498 89 197 7.19E-13 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal K08M4_RS02840 64933bad18605c97253b04bb609f7610 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.7E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS02840 64933bad18605c97253b04bb609f7610 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.7E-5 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS02840 64933bad18605c97253b04bb609f7610 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 3.0E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS02840 64933bad18605c97253b04bb609f7610 201 SUPERFAMILY SSF46689 8 83 2.15E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS02840 64933bad18605c97253b04bb609f7610 201 Gene3D G3DSA:1.10.357.10 6 197 2.6E-32 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS06555 6d6f68e40b5deec32cc87fb3a33e4ad8 268 Pfam PF02654 Cobalamin-5-phosphate synthase 23 256 4.2E-50 T 05-07-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 K08M4_RS06555 6d6f68e40b5deec32cc87fb3a33e4ad8 268 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 268 45.442 T 05-07-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 K08M4_RS09875 4a5c66f8aaa113a3671974ededfd3b3f 127 Pfam PF07233 Protein of unknown function (DUF1425) 35 125 3.0E-28 T 05-07-2017 IPR010824 Protein of unknown function DUF1425 K08M4_RS06910 b74c38bd4b7a2cd115f13bf23ec314ef 251 Gene3D G3DSA:3.40.50.150 10 250 1.2E-30 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS06910 b74c38bd4b7a2cd115f13bf23ec314ef 251 SUPERFAMILY SSF53335 10 250 3.4E-37 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS06910 b74c38bd4b7a2cd115f13bf23ec314ef 251 Pfam PF13649 Methyltransferase domain 49 139 5.9E-11 T 05-07-2017 K08M4_RS14050 c14391bdb1106035e726466e2a5060c2 288 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 288 2.5E-115 T 05-07-2017 IPR005229 Conserved hypothetical protein CHP00255 K08M4_RS14050 c14391bdb1106035e726466e2a5060c2 288 Pfam PF08340 Domain of unknown function (DUF1732) 204 288 3.7E-34 T 05-07-2017 IPR013551 Domain of unknown function DUF1732 K08M4_RS14050 c14391bdb1106035e726466e2a5060c2 288 Pfam PF03755 YicC-like family, N-terminal region 2 154 5.8E-44 T 05-07-2017 IPR013527 YicC-like, N-terminal K08M4_RS21625 65d626e2a2fe35052b53a5550cb55289 155 SUPERFAMILY SSF82784 1 152 5.37E-47 T 05-07-2017 IPR003718 OsmC/Ohr family K08M4_RS21625 65d626e2a2fe35052b53a5550cb55289 155 Gene3D G3DSA:3.30.300.20 1 153 4.5E-56 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta K08M4_RS21625 65d626e2a2fe35052b53a5550cb55289 155 Pfam PF02566 OsmC-like protein 56 153 2.3E-15 T 05-07-2017 IPR003718 OsmC/Ohr family K08M4_RS02585 46d99d744e847fc16439a72855c24a8e 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 260 1.9E-15 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS02585 46d99d744e847fc16439a72855c24a8e 277 Gene3D G3DSA:1.10.3720.10 7 264 4.5E-65 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS02585 46d99d744e847fc16439a72855c24a8e 277 SUPERFAMILY SSF161098 7 276 4.49E-66 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS06835 981dd8ba7c41ddb3350650730d363da7 388 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 28 317 1.5E-21 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 K08M4_RS06835 981dd8ba7c41ddb3350650730d363da7 388 SUPERFAMILY SSF52540 7 322 6.14E-26 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06835 981dd8ba7c41ddb3350650730d363da7 388 Gene3D G3DSA:3.40.50.300 7 172 3.3E-33 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06835 981dd8ba7c41ddb3350650730d363da7 388 Gene3D G3DSA:3.40.50.300 212 323 3.3E-33 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12145 2f53a80160d260451b9f2da762c1ca61 792 Gene3D G3DSA:3.20.20.450 521 768 1.4E-73 T 05-07-2017 IPR001633 EAL domain K08M4_RS12145 2f53a80160d260451b9f2da762c1ca61 792 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 338 504 7.4E-34 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS12145 2f53a80160d260451b9f2da762c1ca61 792 SUPERFAMILY SSF141868 522 769 1.83E-69 T 05-07-2017 IPR001633 EAL domain K08M4_RS12145 2f53a80160d260451b9f2da762c1ca61 792 Pfam PF00990 Diguanylate cyclase, GGDEF domain 340 503 3.6E-37 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS12145 2f53a80160d260451b9f2da762c1ca61 792 SMART SM00052 517 760 7.9E-70 T 05-07-2017 IPR001633 EAL domain K08M4_RS12145 2f53a80160d260451b9f2da762c1ca61 792 SUPERFAMILY SSF55073 344 507 6.36E-38 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS12145 2f53a80160d260451b9f2da762c1ca61 792 Pfam PF00563 EAL domain 524 755 1.6E-60 T 05-07-2017 IPR001633 EAL domain K08M4_RS12145 2f53a80160d260451b9f2da762c1ca61 792 Pfam PF00672 HAMP domain 263 329 9.2E-7 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS12145 2f53a80160d260451b9f2da762c1ca61 792 Gene3D G3DSA:3.30.70.270 341 511 1.6E-42 T 05-07-2017 K08M4_RS12145 2f53a80160d260451b9f2da762c1ca61 792 SMART SM00267 328 507 7.0E-38 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS12970 66f67d93acd7cea43ac40f5949adf65c 271 Gene3D G3DSA:1.10.8.100 200 265 2.7E-24 T 05-07-2017 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 K08M4_RS12970 66f67d93acd7cea43ac40f5949adf65c 271 SMART SM00650 25 197 1.8E-87 T 05-07-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 K08M4_RS12970 66f67d93acd7cea43ac40f5949adf65c 271 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 10 263 3.0E-88 T 05-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 K08M4_RS12970 66f67d93acd7cea43ac40f5949adf65c 271 Pfam PF00398 Ribosomal RNA adenine dimethylase 9 264 2.1E-80 T 05-07-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm K08M4_RS12970 66f67d93acd7cea43ac40f5949adf65c 271 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 41 68 - T 05-07-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 K08M4_RS12970 66f67d93acd7cea43ac40f5949adf65c 271 Gene3D G3DSA:3.40.50.150 8 196 1.8E-68 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS12970 66f67d93acd7cea43ac40f5949adf65c 271 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 9 264 55.701 T 05-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 K08M4_RS12970 66f67d93acd7cea43ac40f5949adf65c 271 SUPERFAMILY SSF53335 8 266 1.97E-81 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS07820 402f53c4908303fee126f7f2427cb114 868 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 12 866 0.0 T 05-07-2017 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 K08M4_RS07820 402f53c4908303fee126f7f2427cb114 868 SUPERFAMILY SSF55486 203 450 1.81E-73 T 05-07-2017 K08M4_RS07820 402f53c4908303fee126f7f2427cb114 868 SUPERFAMILY SSF63737 3 192 1.7E-44 T 05-07-2017 K08M4_RS07820 402f53c4908303fee126f7f2427cb114 868 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 125 140 2.1E-9 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 K08M4_RS07820 402f53c4908303fee126f7f2427cb114 868 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 312 324 2.1E-9 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 K08M4_RS07820 402f53c4908303fee126f7f2427cb114 868 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 175 190 2.1E-9 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 K08M4_RS07820 402f53c4908303fee126f7f2427cb114 868 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 293 308 2.1E-9 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 K08M4_RS07820 402f53c4908303fee126f7f2427cb114 868 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 257 267 2.1E-9 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 K08M4_RS07820 402f53c4908303fee126f7f2427cb114 868 Pfam PF01433 Peptidase family M1 43 383 5.6E-69 T 05-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 K08M4_RS07820 402f53c4908303fee126f7f2427cb114 868 Gene3D G3DSA:1.25.50.10 545 867 1.9E-114 T 05-07-2017 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal K08M4_RS07820 402f53c4908303fee126f7f2427cb114 868 Pfam PF11940 Domain of unknown function (DUF3458) 457 824 9.2E-130 T 05-07-2017 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal K08M4_RS07820 402f53c4908303fee126f7f2427cb114 868 Gene3D G3DSA:1.10.390.10 307 450 1.9E-32 T 05-07-2017 K08M4_RS11325 16a3e0611cf96015dd6662d7b4e8d9d2 63 Pfam PF14056 Domain of unknown function (DUF4250) 8 62 1.0E-20 T 05-07-2017 IPR025346 Protein of unknown function DUF4250 K08M4_RS17355 54d9cf00c89bd50d3c82d89eb42cc5df 179 SMART SM01322 1 174 3.1E-107 T 05-07-2017 IPR009822 YaeQ K08M4_RS17355 54d9cf00c89bd50d3c82d89eb42cc5df 179 Pfam PF07152 YaeQ protein 1 172 5.2E-70 T 05-07-2017 IPR009822 YaeQ K08M4_RS17355 54d9cf00c89bd50d3c82d89eb42cc5df 179 PIRSF PIRSF011484 1 179 1.6E-68 T 05-07-2017 IPR009822 YaeQ K08M4_RS17355 54d9cf00c89bd50d3c82d89eb42cc5df 179 SUPERFAMILY SSF52980 2 178 4.83E-67 T 05-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 K08M4_RS17355 54d9cf00c89bd50d3c82d89eb42cc5df 179 Gene3D G3DSA:3.10.640.10 1 178 2.6E-72 T 05-07-2017 K08M4_RS03875 cd68659a1a2d20289c7ead44fb9ecb0e 237 Pfam PF06178 Oligogalacturonate-specific porin protein (KdgM) 99 187 8.9E-5 T 05-07-2017 IPR009331 Oligogalacturonate-specific porin K08M4_RS03875 cd68659a1a2d20289c7ead44fb9ecb0e 237 Gene3D G3DSA:2.40.230.30 42 237 4.2E-28 T 05-07-2017 K08M4_RS15005 ddc05c801a389ccd487342e136a50e4d 245 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS15005 ddc05c801a389ccd487342e136a50e4d 245 Pfam PF00005 ABC transporter 17 168 5.1E-32 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS15005 ddc05c801a389ccd487342e136a50e4d 245 Gene3D G3DSA:3.40.50.300 1 240 1.2E-81 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15005 ddc05c801a389ccd487342e136a50e4d 245 PIRSF PIRSF039085 1 244 8.1E-108 T 05-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 K08M4_RS15005 ddc05c801a389ccd487342e136a50e4d 245 SMART SM00382 26 216 6.2E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS15005 ddc05c801a389ccd487342e136a50e4d 245 SUPERFAMILY SSF52540 1 238 1.05E-76 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS08485 6af43647ba12b50366991a088ac48191 180 SUPERFAMILY SSF111126 1 178 1.36E-46 T 05-07-2017 IPR024096 NO signalling/Golgi transport ligand-binding domain K08M4_RS08485 6af43647ba12b50366991a088ac48191 180 Pfam PF07700 Haem-NO-binding 2 162 7.7E-38 T 05-07-2017 IPR011644 Heme-NO binding GO:0020037 KEGG: 00230+4.6.1.2|Reactome: R-HSA-392154 K08M4_RS08485 6af43647ba12b50366991a088ac48191 180 Gene3D G3DSA:3.90.1520.10 1 179 1.4E-55 T 05-07-2017 K08M4_RS16260 d83ea619fd80ee2f132580ce19e41123 308 Pfam PF00246 Zinc carboxypeptidase 73 146 9.5E-7 T 05-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 K08M4_RS16260 d83ea619fd80ee2f132580ce19e41123 308 Gene3D G3DSA:3.40.630.10 13 211 2.9E-67 T 05-07-2017 K08M4_RS16260 d83ea619fd80ee2f132580ce19e41123 308 Gene3D G3DSA:3.40.630.10 248 302 2.9E-67 T 05-07-2017 K08M4_RS16260 d83ea619fd80ee2f132580ce19e41123 308 SUPERFAMILY SSF53187 36 301 3.24E-36 T 05-07-2017 K08M4_RS01395 683221f381af4aa4e98d301b670d0165 198 Gene3D G3DSA:3.10.50.40 2 80 1.2E-20 T 05-07-2017 K08M4_RS01395 683221f381af4aa4e98d301b670d0165 198 Gene3D G3DSA:3.10.50.40 126 141 1.2E-20 T 05-07-2017 K08M4_RS01395 683221f381af4aa4e98d301b670d0165 198 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 136 1.1E-12 T 05-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 K08M4_RS01395 683221f381af4aa4e98d301b670d0165 198 SUPERFAMILY SSF54534 2 140 3.34E-36 T 05-07-2017 K08M4_RS08980 57dd0c879240146c1a3baa829b6bf25d 190 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 34 165 2.5E-26 T 05-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component K08M4_RS21645 ab87dd3e381f103d6052fbd8ad6b5f54 429 SMART SM00387 326 429 1.3E-21 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21645 ab87dd3e381f103d6052fbd8ad6b5f54 429 Pfam PF00512 His Kinase A (phospho-acceptor) domain 217 281 4.4E-7 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS21645 ab87dd3e381f103d6052fbd8ad6b5f54 429 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 326 414 6.9E-15 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21645 ab87dd3e381f103d6052fbd8ad6b5f54 429 SUPERFAMILY SSF158472 163 210 4.05E-5 T 05-07-2017 K08M4_RS21645 ab87dd3e381f103d6052fbd8ad6b5f54 429 SUPERFAMILY SSF55874 270 426 3.67E-30 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21645 ab87dd3e381f103d6052fbd8ad6b5f54 429 SUPERFAMILY SSF47384 198 282 8.44E-13 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS21645 ab87dd3e381f103d6052fbd8ad6b5f54 429 Gene3D G3DSA:1.10.287.130 205 277 3.2E-9 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS21645 ab87dd3e381f103d6052fbd8ad6b5f54 429 Gene3D G3DSA:3.30.565.10 283 418 6.6E-26 T 05-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain K08M4_RS21645 ab87dd3e381f103d6052fbd8ad6b5f54 429 SMART SM00388 215 281 2.6E-7 T 05-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 K08M4_RS13660 90bd3ad01d6c54bc1f092c6b9b6530fa 295 SUPERFAMILY SSF103481 217 293 3.92E-10 T 05-07-2017 K08M4_RS13660 90bd3ad01d6c54bc1f092c6b9b6530fa 295 SUPERFAMILY SSF103481 36 140 4.45E-10 T 05-07-2017 K08M4_RS13660 90bd3ad01d6c54bc1f092c6b9b6530fa 295 Pfam PF00892 EamA-like transporter family 5 134 2.5E-15 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS13660 90bd3ad01d6c54bc1f092c6b9b6530fa 295 Pfam PF00892 EamA-like transporter family 156 294 2.8E-17 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS09830 37cc006390429bda6e6725d74d8b54de 406 Pfam PF02687 FtsX-like permease family 275 399 7.2E-18 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 K08M4_RS09830 37cc006390429bda6e6725d74d8b54de 406 Pfam PF12704 MacB-like periplasmic core domain 33 210 8.5E-13 T 05-07-2017 IPR025857 MacB-like periplasmic core domain K08M4_RS09830 37cc006390429bda6e6725d74d8b54de 406 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 8 406 2.0E-133 T 05-07-2017 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 K08M4_RS08020 305368adee36db6d9bfa637872a2f764 404 PRINTS PR00143 Citrate synthase signature 205 220 2.7E-35 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS08020 305368adee36db6d9bfa637872a2f764 404 PRINTS PR00143 Citrate synthase signature 357 371 2.7E-35 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS08020 305368adee36db6d9bfa637872a2f764 404 PRINTS PR00143 Citrate synthase signature 154 167 2.7E-35 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS08020 305368adee36db6d9bfa637872a2f764 404 PRINTS PR00143 Citrate synthase signature 337 353 2.7E-35 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS08020 305368adee36db6d9bfa637872a2f764 404 PRINTS PR00143 Citrate synthase signature 280 300 2.7E-35 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS08020 305368adee36db6d9bfa637872a2f764 404 PRINTS PR00143 Citrate synthase signature 227 255 2.7E-35 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS08020 305368adee36db6d9bfa637872a2f764 404 ProSitePatterns PS00480 Citrate synthase signature. 287 299 - T 05-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 K08M4_RS08020 305368adee36db6d9bfa637872a2f764 404 PIRSF PIRSF001369 34 404 3.9E-114 T 05-07-2017 IPR024176 Citrate synthase, bacterial-type K08M4_RS08020 305368adee36db6d9bfa637872a2f764 404 SUPERFAMILY SSF48256 38 403 1.02E-122 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS08020 305368adee36db6d9bfa637872a2f764 404 Gene3D G3DSA:1.10.230.10 267 351 4.7E-31 T 05-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 K08M4_RS08020 305368adee36db6d9bfa637872a2f764 404 Gene3D G3DSA:1.10.580.10 45 266 1.6E-72 T 05-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 K08M4_RS08020 305368adee36db6d9bfa637872a2f764 404 Pfam PF00285 Citrate synthase, C-terminal domain 39 386 4.2E-112 T 05-07-2017 IPR002020 Citrate synthase GO:0046912 K08M4_RS08020 305368adee36db6d9bfa637872a2f764 404 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 39 404 5.8E-157 T 05-07-2017 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 K08M4_RS04810 7ab74868fd18b50de5b5695d19406bf1 171 Pfam PF11993 Ribosomal S4P (gammaproteobacterial) 5 167 3.8E-63 T 05-07-2017 IPR021879 Ribosomal S4P (gammaproteobacterial) K08M4_RS10790 19e46db5de8bb90c17d48afaacc74aa5 535 Pfam PF10088 Uncharacterised protein conserved in bacteria (DUF2326) 413 520 5.8E-10 T 05-07-2017 IPR018760 Protein of unknown function DUF2326 K08M4_RS10790 19e46db5de8bb90c17d48afaacc74aa5 535 Gene3D G3DSA:3.40.50.300 13 115 1.1E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05020 4681e476db56cc20cff0700d68e08774 206 SUPERFAMILY SSF101327 15 143 5.75E-5 T 05-07-2017 IPR011978 Uncharacterised protein family UPF0149 K08M4_RS05020 4681e476db56cc20cff0700d68e08774 206 Pfam PF03695 Uncharacterised protein family (UPF0149) 14 161 1.9E-7 T 05-07-2017 IPR011978 Uncharacterised protein family UPF0149 K08M4_RS05020 4681e476db56cc20cff0700d68e08774 206 Gene3D G3DSA:3.10.450.50 171 204 2.0E-11 T 05-07-2017 IPR032710 NTF2-like domain K08M4_RS05020 4681e476db56cc20cff0700d68e08774 206 SUPERFAMILY SSF103642 184 204 9.48E-7 T 05-07-2017 K08M4_RS05020 4681e476db56cc20cff0700d68e08774 206 Pfam PF02810 SEC-C motif 186 204 5.9E-9 T 05-07-2017 IPR004027 SEC-C motif K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 Pfam PF00970 Oxidoreductase FAD-binding domain 158 261 6.4E-10 T 05-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 Gene3D G3DSA:1.10.490.10 3 141 2.9E-52 T 05-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 Pfam PF00042 Globin 8 99 3.0E-12 T 05-07-2017 IPR000971 Globin GO:0019825|GO:0020037 K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 SUPERFAMILY SSF52343 262 395 1.44E-25 T 05-07-2017 K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 Pfam PF00175 Oxidoreductase NAD-binding domain 270 373 1.5E-11 T 05-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 SUPERFAMILY SSF46458 3 143 2.33E-38 T 05-07-2017 IPR009050 Globin-like K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 Gene3D G3DSA:2.40.30.10 151 260 4.7E-34 T 05-07-2017 K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 SUPERFAMILY SSF63380 154 261 7.66E-27 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 PRINTS PR00410 Phenol hydroxylase reductase family signature 185 197 3.6E-6 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 PRINTS PR00410 Phenol hydroxylase reductase family signature 269 288 3.6E-6 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 PRINTS PR00410 Phenol hydroxylase reductase family signature 360 368 3.6E-6 T 05-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 185 195 8.7E-7 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 206 213 8.7E-7 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 269 288 8.7E-7 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 360 368 8.7E-7 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 234 243 8.7E-7 T 05-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 K08M4_RS17725 511993104c72bf42c74ba339ee9fbc7c 398 Gene3D G3DSA:3.40.50.80 262 395 3.9E-26 T 05-07-2017 K08M4_RS04430 bc72e006354e62f9f13062918bd2bd1e 87 Gene3D G3DSA:3.30.1070.10 34 86 7.0E-20 T 05-07-2017 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 K08M4_RS04430 bc72e006354e62f9f13062918bd2bd1e 87 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 85 18.123 T 05-07-2017 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 K08M4_RS04430 bc72e006354e62f9f13062918bd2bd1e 87 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 84 3.5E-32 T 05-07-2017 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 K08M4_RS04430 bc72e006354e62f9f13062918bd2bd1e 87 SUPERFAMILY SSF55229 34 86 8.63E-16 T 05-07-2017 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 K08M4_RS04430 bc72e006354e62f9f13062918bd2bd1e 87 Pfam PF03776 Septum formation topological specificity factor MinE 14 83 2.1E-21 T 05-07-2017 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 K08M4_RS00390 2a60fbbe65f3b5b7e1370558ad35f615 408 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 69 397 1.7E-101 T 05-07-2017 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX K08M4_RS06975 21baae5222f9ef9e8d6b85936ca81012 144 Gene3D G3DSA:3.40.630.30 16 128 1.0E-15 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS06975 21baae5222f9ef9e8d6b85936ca81012 144 SUPERFAMILY SSF55729 2 129 5.15E-18 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS06975 21baae5222f9ef9e8d6b85936ca81012 144 Pfam PF00583 Acetyltransferase (GNAT) family 50 124 1.1E-8 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS04020 a00b314d47ae8e5b0dc83cd324b5019e 105 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 4 99 3.0E-23 T 05-07-2017 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 K08M4_RS04020 a00b314d47ae8e5b0dc83cd324b5019e 105 SUPERFAMILY SSF101498 2 99 1.18E-19 T 05-07-2017 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 K08M4_RS04020 a00b314d47ae8e5b0dc83cd324b5019e 105 Pfam PF04316 Anti-sigma-28 factor, FlgM 43 96 3.2E-19 T 05-07-2017 IPR031316 Anti-sigma-28 factor FlgM, C-terminal K08M4_RS20290 f97f5da4882c16b65a347f720a4fe8f3 107 Gene3D G3DSA:3.30.70.20 4 102 2.7E-20 T 05-07-2017 K08M4_RS20290 f97f5da4882c16b65a347f720a4fe8f3 107 Pfam PF11953 Domain of unknown function (DUF3470) 68 107 9.9E-18 T 05-07-2017 IPR022569 Ferredoxin, C-terminal K08M4_RS20290 f97f5da4882c16b65a347f720a4fe8f3 107 SUPERFAMILY SSF54862 3 88 6.7E-23 T 05-07-2017 K08M4_RS20290 f97f5da4882c16b65a347f720a4fe8f3 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 5.5E-12 T 05-07-2017 IPR000813 7Fe ferredoxin GO:0009055 K08M4_RS20290 f97f5da4882c16b65a347f720a4fe8f3 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 5.5E-12 T 05-07-2017 IPR000813 7Fe ferredoxin GO:0009055 K08M4_RS20290 f97f5da4882c16b65a347f720a4fe8f3 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 5.5E-12 T 05-07-2017 IPR000813 7Fe ferredoxin GO:0009055 K08M4_RS20290 f97f5da4882c16b65a347f720a4fe8f3 107 Pfam PF13187 4Fe-4S dicluster domain 8 55 9.3E-7 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain K08M4_RS02155 bcb23c035d8a80d6919b6d86a4b70e1b 238 Gene3D G3DSA:3.20.20.10 1 234 6.0E-91 T 05-07-2017 IPR029066 PLP-binding barrel K08M4_RS02155 bcb23c035d8a80d6919b6d86a4b70e1b 238 PIRSF PIRSF004848 1 236 3.1E-74 T 05-07-2017 IPR011078 Uncharacterised protein family UPF0001 K08M4_RS02155 bcb23c035d8a80d6919b6d86a4b70e1b 238 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 80 94 - T 05-07-2017 IPR011078 Uncharacterised protein family UPF0001 K08M4_RS02155 bcb23c035d8a80d6919b6d86a4b70e1b 238 Pfam PF01168 Alanine racemase, N-terminal domain 8 230 7.4E-32 T 05-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 K08M4_RS02155 bcb23c035d8a80d6919b6d86a4b70e1b 238 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 230 4.5E-83 T 05-07-2017 IPR011078 Uncharacterised protein family UPF0001 K08M4_RS02155 bcb23c035d8a80d6919b6d86a4b70e1b 238 SUPERFAMILY SSF51419 1 228 2.22E-79 T 05-07-2017 IPR029066 PLP-binding barrel K08M4_RS20260 09558485a6e38583dee12e1d8b37ea31 147 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 108 5.3E-24 T 05-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 K08M4_RS20260 09558485a6e38583dee12e1d8b37ea31 147 SUPERFAMILY SSF53927 8 136 5.81E-29 T 05-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 K08M4_RS20260 09558485a6e38583dee12e1d8b37ea31 147 PIRSF PIRSF006019 1 145 4.3E-43 T 05-07-2017 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-500753 K08M4_RS20260 09558485a6e38583dee12e1d8b37ea31 147 Gene3D G3DSA:3.40.140.10 5 145 1.1E-30 T 05-07-2017 K08M4_RS20260 09558485a6e38583dee12e1d8b37ea31 147 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 67 99 - T 05-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 K08M4_RS03170 e280c29e721658faffb30d70155f9dbf 337 Pfam PF01136 Peptidase family U32 75 336 3.3E-70 T 05-07-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 K08M4_RS03170 e280c29e721658faffb30d70155f9dbf 337 ProSitePatterns PS01276 Peptidase family U32 signature. 163 181 - T 05-07-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 K08M4_RS12770 474c5c8326737632c3010a49fb1fe140 203 TIGRFAM TIGR04211 SH3_and_anchor: SH3 domain protein 24 202 1.1E-52 T 05-07-2017 IPR016476 SH3 domain protein K08M4_RS12770 474c5c8326737632c3010a49fb1fe140 203 SMART SM00287 20 86 7.6E-11 T 05-07-2017 IPR003646 SH3-like domain, bacterial-type K08M4_RS12770 474c5c8326737632c3010a49fb1fe140 203 Pfam PF08239 Bacterial SH3 domain 32 83 2.8E-8 T 05-07-2017 IPR003646 SH3-like domain, bacterial-type K08M4_RS12770 474c5c8326737632c3010a49fb1fe140 203 PIRSF PIRSF006158 1 203 3.5E-69 T 05-07-2017 IPR016476 SH3 domain protein K08M4_RS12770 474c5c8326737632c3010a49fb1fe140 203 Gene3D G3DSA:1.20.58.70 83 154 8.1E-4 T 05-07-2017 K08M4_RS21010 7a069ac74957b4efebf5bbe6d62ee5c7 541 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 462 1.8E-81 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain K08M4_RS21010 7a069ac74957b4efebf5bbe6d62ee5c7 541 PIRSF PIRSF002741 2 541 2.7E-110 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 K08M4_RS21010 7a069ac74957b4efebf5bbe6d62ee5c7 541 Gene3D G3DSA:3.10.105.10 309 510 2.1E-59 T 05-07-2017 K08M4_RS21010 7a069ac74957b4efebf5bbe6d62ee5c7 541 SUPERFAMILY SSF53850 33 533 6.79E-136 T 05-07-2017 K08M4_RS21010 7a069ac74957b4efebf5bbe6d62ee5c7 541 Gene3D G3DSA:3.40.190.10 160 308 2.9E-48 T 05-07-2017 K08M4_RS06290 1f31c71ef88f0f2e70d4311fc39f9b3d 158 Pfam PF13508 Acetyltransferase (GNAT) domain 67 134 1.6E-7 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS06290 1f31c71ef88f0f2e70d4311fc39f9b3d 158 SUPERFAMILY SSF55729 6 140 9.22E-17 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS06290 1f31c71ef88f0f2e70d4311fc39f9b3d 158 Gene3D G3DSA:3.40.630.30 7 154 4.9E-16 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS12190 50a2bcbdef680d067545350c51efcd7d 329 SUPERFAMILY SSF51445 2 288 1.04E-86 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS12190 50a2bcbdef680d067545350c51efcd7d 329 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 229 246 - T 05-07-2017 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 K08M4_RS12190 50a2bcbdef680d067545350c51efcd7d 329 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 3 327 45.433 T 05-07-2017 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 K08M4_RS12190 50a2bcbdef680d067545350c51efcd7d 329 Gene3D G3DSA:3.20.20.300 3 284 4.5E-93 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 K08M4_RS12190 50a2bcbdef680d067545350c51efcd7d 329 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 9 286 1.1E-86 T 05-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 K08M4_RS04670 585cdde76d9a822fdca7b92baee1ab6e 294 PIRSF PIRSF016020 7 294 2.3E-65 T 05-07-2017 IPR025532 Glucose-6-phosphate 1-epimerase K08M4_RS04670 585cdde76d9a822fdca7b92baee1ab6e 294 Pfam PF01263 Aldose 1-epimerase 26 290 2.6E-51 T 05-07-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 K08M4_RS04670 585cdde76d9a822fdca7b92baee1ab6e 294 SUPERFAMILY SSF74650 7 285 4.77E-73 T 05-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 K08M4_RS04670 585cdde76d9a822fdca7b92baee1ab6e 294 Gene3D G3DSA:2.70.98.10 13 291 2.5E-88 T 05-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 K08M4_RS06410 2f50f0835c4ea835974c0d8dc28059bf 233 Gene3D G3DSA:1.10.10.10 1 63 7.4E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06410 2f50f0835c4ea835974c0d8dc28059bf 233 SUPERFAMILY SSF46785 1 61 8.28E-10 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06410 2f50f0835c4ea835974c0d8dc28059bf 233 Pfam PF08279 HTH domain 6 60 4.0E-18 T 05-07-2017 IPR013196 Helix-turn-helix, type 11 K08M4_RS06410 2f50f0835c4ea835974c0d8dc28059bf 233 Pfam PF13280 WYL domain 138 228 1.7E-16 T 05-07-2017 IPR026881 WYL domain K08M4_RS15580 7baf0c9e91d3a1a9fef4da512a984170 351 Pfam PF01758 Sodium Bile acid symporter family 50 246 1.4E-58 T 05-07-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 K08M4_RS15580 7baf0c9e91d3a1a9fef4da512a984170 351 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 5 334 3.5E-136 T 05-07-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 K08M4_RS15580 7baf0c9e91d3a1a9fef4da512a984170 351 PIRSF PIRSF005508 1 350 5.0E-134 T 05-07-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 K08M4_RS10935 61c0f68890e456c438049fdcb4c31ce4 153 Pfam PF11143 Protein of unknown function (DUF2919) 3 147 2.9E-52 T 05-07-2017 IPR021318 Protein of unknown function DUF2919 K08M4_RS08680 81c6faeb60eeb12457dfab8e3fd26bbe 209 SUPERFAMILY SSF48498 80 207 1.51E-41 T 05-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal K08M4_RS08680 81c6faeb60eeb12457dfab8e3fd26bbe 209 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 54 - T 05-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site K08M4_RS08680 81c6faeb60eeb12457dfab8e3fd26bbe 209 Gene3D G3DSA:1.10.357.10 3 206 8.4E-37 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS08680 81c6faeb60eeb12457dfab8e3fd26bbe 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.9E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS08680 81c6faeb60eeb12457dfab8e3fd26bbe 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.9E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS08680 81c6faeb60eeb12457dfab8e3fd26bbe 209 SUPERFAMILY SSF46689 3 74 3.13E-18 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS08680 81c6faeb60eeb12457dfab8e3fd26bbe 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 4.6E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS02930 2178898c2e5c01d76afce80ff1877fa3 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 05-07-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 K08M4_RS02930 2178898c2e5c01d76afce80ff1877fa3 112 SUPERFAMILY SSF54913 1 112 4.13E-45 T 05-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta K08M4_RS02930 2178898c2e5c01d76afce80ff1877fa3 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.8E-43 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 K08M4_RS02930 2178898c2e5c01d76afce80ff1877fa3 112 PRINTS PR00340 P-II protein signature 23 41 5.2E-41 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 K08M4_RS02930 2178898c2e5c01d76afce80ff1877fa3 112 PRINTS PR00340 P-II protein signature 83 103 5.2E-41 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 K08M4_RS02930 2178898c2e5c01d76afce80ff1877fa3 112 PRINTS PR00340 P-II protein signature 2 17 5.2E-41 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 K08M4_RS02930 2178898c2e5c01d76afce80ff1877fa3 112 PRINTS PR00340 P-II protein signature 52 75 5.2E-41 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 K08M4_RS02930 2178898c2e5c01d76afce80ff1877fa3 112 Gene3D G3DSA:3.30.70.120 1 112 3.6E-51 T 05-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal K08M4_RS02930 2178898c2e5c01d76afce80ff1877fa3 112 PIRSF PIRSF039144 1 112 9.0E-56 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 K08M4_RS02930 2178898c2e5c01d76afce80ff1877fa3 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 05-07-2017 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 K08M4_RS02930 2178898c2e5c01d76afce80ff1877fa3 112 SMART SM00938 4 105 4.2E-69 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 K08M4_RS09400 4ce6cc8b22346a1f01fd993e77a18d0e 60 Pfam PF06796 Periplasmic nitrate reductase protein NapE 6 55 6.8E-24 T 05-07-2017 IPR010649 Nitrate/trimethylamine N-oxide reductase NapE/TorE K08M4_RS09400 4ce6cc8b22346a1f01fd993e77a18d0e 60 TIGRFAM TIGR02972 TMAO_torE: trimethylamine N-oxide reductase system, TorE protein 9 57 4.4E-27 T 05-07-2017 IPR014316 Trimethylamine N-oxide reductase system, TorE K08M4_RS01700 d16fb6403b0230ec1c79b62e7ce374cf 238 Gene3D G3DSA:3.40.50.300 9 228 2.5E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01700 d16fb6403b0230ec1c79b62e7ce374cf 238 Pfam PF00005 ABC transporter 31 184 1.3E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS01700 d16fb6403b0230ec1c79b62e7ce374cf 238 SMART SM00382 36 232 1.2E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS01700 d16fb6403b0230ec1c79b62e7ce374cf 238 SUPERFAMILY SSF52540 7 229 3.69E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10220 90247b5136f0a32313f50d63164055d1 221 Gene3D G3DSA:3.40.198.10 59 127 9.8E-4 T 05-07-2017 IPR001615 Delta-endotoxin CytB GO:0005576|GO:0009405 K08M4_RS13030 325f7b59468baca1a7f751b78f18597e 156 Hamap MF_00173 Arginine repressor [argR]. 1 155 58.805 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 K08M4_RS13030 325f7b59468baca1a7f751b78f18597e 156 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 89 146 5.0E-22 T 05-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 K08M4_RS13030 325f7b59468baca1a7f751b78f18597e 156 Gene3D G3DSA:3.30.1360.40 80 154 8.1E-26 T 05-07-2017 IPR024946 Arginine repressor C-terminal-like domain K08M4_RS13030 325f7b59468baca1a7f751b78f18597e 156 SUPERFAMILY SSF46785 4 77 1.09E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS13030 325f7b59468baca1a7f751b78f18597e 156 Pfam PF01316 Arginine repressor, DNA binding domain 6 74 3.4E-23 T 05-07-2017 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 K08M4_RS13030 325f7b59468baca1a7f751b78f18597e 156 SUPERFAMILY SSF55252 82 151 2.49E-19 T 05-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 K08M4_RS13030 325f7b59468baca1a7f751b78f18597e 156 Pfam PF02863 Arginine repressor, C-terminal domain 82 147 3.6E-21 T 05-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 K08M4_RS13030 325f7b59468baca1a7f751b78f18597e 156 TIGRFAM TIGR01529 argR_whole: arginine repressor 10 151 4.4E-43 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 K08M4_RS13030 325f7b59468baca1a7f751b78f18597e 156 Gene3D G3DSA:1.10.10.10 2 77 4.8E-34 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS13030 325f7b59468baca1a7f751b78f18597e 156 PRINTS PR01467 Bacterial arginine repressor signature 90 103 8.2E-24 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 K08M4_RS13030 325f7b59468baca1a7f751b78f18597e 156 PRINTS PR01467 Bacterial arginine repressor signature 42 57 8.2E-24 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 K08M4_RS13030 325f7b59468baca1a7f751b78f18597e 156 PRINTS PR01467 Bacterial arginine repressor signature 121 136 8.2E-24 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 K08M4_RS13030 325f7b59468baca1a7f751b78f18597e 156 PRINTS PR01467 Bacterial arginine repressor signature 25 38 8.2E-24 T 05-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 K08M4_RS17740 1ecd47749045e08fd14a846723396867 327 SMART SM00833 241 324 0.009 T 05-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal K08M4_RS17740 1ecd47749045e08fd14a846723396867 327 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 178 4.3E-42 T 05-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain K08M4_RS17740 1ecd47749045e08fd14a846723396867 327 Gene3D G3DSA:3.40.50.300 3 194 3.2E-48 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS17740 1ecd47749045e08fd14a846723396867 327 SUPERFAMILY SSF52540 3 167 8.71E-27 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10570 89c3ef91a23da5d94ab09ab202dbf36f 939 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 15 934 0.0 T 05-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 K08M4_RS10570 89c3ef91a23da5d94ab09ab202dbf36f 939 SUPERFAMILY SSF52518 578 795 7.23E-52 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS10570 89c3ef91a23da5d94ab09ab202dbf36f 939 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 792 934 2.2E-53 T 05-07-2017 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 K08M4_RS10570 89c3ef91a23da5d94ab09ab202dbf36f 939 PIRSF PIRSF000157 1 936 0.0 T 05-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 K08M4_RS10570 89c3ef91a23da5d94ab09ab202dbf36f 939 Gene3D G3DSA:3.40.50.970 593 791 5.0E-26 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS10570 89c3ef91a23da5d94ab09ab202dbf36f 939 Pfam PF02779 Transketolase, pyrimidine binding domain 594 789 7.1E-66 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain K08M4_RS10570 89c3ef91a23da5d94ab09ab202dbf36f 939 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 12 49 3.8E-16 T 05-07-2017 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 K08M4_RS10570 89c3ef91a23da5d94ab09ab202dbf36f 939 Pfam PF00676 Dehydrogenase E1 component 221 515 6.0E-48 T 05-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 K08M4_RS10570 89c3ef91a23da5d94ab09ab202dbf36f 939 Gene3D G3DSA:3.40.50.970 163 553 3.6E-77 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS10570 89c3ef91a23da5d94ab09ab202dbf36f 939 SMART SM00861 595 788 1.6E-63 T 05-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain K08M4_RS10570 89c3ef91a23da5d94ab09ab202dbf36f 939 SUPERFAMILY SSF52518 122 532 6.04E-86 T 05-07-2017 IPR029061 Thiamin diphosphate-binding fold K08M4_RS15900 d5f9d4c27501fb08b26a44dc96f471c3 182 Hamap MF_01572 UPF0397 protein . 1 182 20.689 T 05-07-2017 IPR022914 Protein of unknown function UPF0397 K08M4_RS15900 d5f9d4c27501fb08b26a44dc96f471c3 182 Pfam PF07155 ECF-type riboflavin transporter, S component 2 171 4.2E-42 T 05-07-2017 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 K08M4_RS09530 20dec03f5a94bf15a72b40e5d3687151 205 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 9 194 8.0E-96 T 05-07-2017 IPR007451 Uncharacterised protein family UPF0274 K08M4_RS09530 20dec03f5a94bf15a72b40e5d3687151 205 SUPERFAMILY SSF101322 2 204 6.41E-79 T 05-07-2017 IPR007451 Uncharacterised protein family UPF0274 K08M4_RS09530 20dec03f5a94bf15a72b40e5d3687151 205 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 1 203 35.629 T 05-07-2017 IPR007451 Uncharacterised protein family UPF0274 K08M4_RS09530 20dec03f5a94bf15a72b40e5d3687151 205 Gene3D G3DSA:1.10.3890.10 2 205 8.9E-87 T 05-07-2017 IPR007451 Uncharacterised protein family UPF0274 K08M4_RS09530 20dec03f5a94bf15a72b40e5d3687151 205 Pfam PF04356 Protein of unknown function (DUF489) 7 195 9.0E-76 T 05-07-2017 IPR007451 Uncharacterised protein family UPF0274 K08M4_RS09655 20dec03f5a94bf15a72b40e5d3687151 205 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 9 194 8.0E-96 T 05-07-2017 IPR007451 Uncharacterised protein family UPF0274 K08M4_RS09655 20dec03f5a94bf15a72b40e5d3687151 205 SUPERFAMILY SSF101322 2 204 6.41E-79 T 05-07-2017 IPR007451 Uncharacterised protein family UPF0274 K08M4_RS09655 20dec03f5a94bf15a72b40e5d3687151 205 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 1 203 35.629 T 05-07-2017 IPR007451 Uncharacterised protein family UPF0274 K08M4_RS09655 20dec03f5a94bf15a72b40e5d3687151 205 Gene3D G3DSA:1.10.3890.10 2 205 8.9E-87 T 05-07-2017 IPR007451 Uncharacterised protein family UPF0274 K08M4_RS09655 20dec03f5a94bf15a72b40e5d3687151 205 Pfam PF04356 Protein of unknown function (DUF489) 7 195 9.0E-76 T 05-07-2017 IPR007451 Uncharacterised protein family UPF0274 K08M4_RS16370 09749a400e467d83753598b3d2d1a8e3 173 Pfam PF06228 Haem utilisation ChuX/HutX 32 169 1.1E-33 T 05-07-2017 IPR010413 Heme utilization carrier protein HutX-like K08M4_RS16370 09749a400e467d83753598b3d2d1a8e3 173 Gene3D G3DSA:3.40.1570.10 6 172 3.6E-72 T 05-07-2017 K08M4_RS16370 09749a400e467d83753598b3d2d1a8e3 173 PIRSF PIRSF030840 3 173 2.6E-62 T 05-07-2017 IPR010413 Heme utilization carrier protein HutX-like K08M4_RS16370 09749a400e467d83753598b3d2d1a8e3 173 SUPERFAMILY SSF144064 10 172 1.57E-57 T 05-07-2017 K08M4_RS16370 09749a400e467d83753598b3d2d1a8e3 173 TIGRFAM TIGR04108 HutX: putative heme utilization carrier protein HutX 16 169 1.2E-62 T 05-07-2017 IPR010413 Heme utilization carrier protein HutX-like K08M4_RS10590 34276452f1a6472f0ee213565daac3d0 130 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 86 99 - T 05-07-2017 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS10590 34276452f1a6472f0ee213565daac3d0 130 SUPERFAMILY SSF81343 8 130 2.78E-34 T 05-07-2017 K08M4_RS10590 34276452f1a6472f0ee213565daac3d0 130 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 8 124 2.8E-29 T 05-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS10590 34276452f1a6472f0ee213565daac3d0 130 PIRSF PIRSF000178 3 130 3.8E-32 T 05-07-2017 K08M4_RS10590 34276452f1a6472f0ee213565daac3d0 130 Gene3D G3DSA:1.20.1300.10 6 130 6.6E-41 T 05-07-2017 K08M4_RS10590 34276452f1a6472f0ee213565daac3d0 130 ProSitePatterns PS01000 Succinate dehydrogenase cytochrome b subunit signature 1. 11 35 - T 05-07-2017 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS10590 34276452f1a6472f0ee213565daac3d0 130 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 9 127 2.3E-39 T 05-07-2017 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 K08M4_RS01705 3486f0fdbeb9c9e16270ba89c7e338ef 245 Pfam PF10986 Protein of unknown function (DUF2796) 28 239 1.1E-31 T 05-07-2017 IPR021253 Protein of unknown function DUF2796 K08M4_RS19560 fa16150dedbab782d3cdb68cb26c77ad 107 SUPERFAMILY SSF143410 1 104 3.53E-32 T 05-07-2017 IPR023389 DOPA-like domain K08M4_RS19560 fa16150dedbab782d3cdb68cb26c77ad 107 Pfam PF08883 Dopa 4,5-dioxygenase family 2 100 8.8E-26 T 05-07-2017 IPR014980 Dopa 4,5-dioxygenase K08M4_RS19560 fa16150dedbab782d3cdb68cb26c77ad 107 PIRSF PIRSF028139 1 107 8.1E-37 T 05-07-2017 IPR014980 Dopa 4,5-dioxygenase K08M4_RS19560 fa16150dedbab782d3cdb68cb26c77ad 107 Gene3D G3DSA:3.30.70.1240 1 104 1.1E-31 T 05-07-2017 IPR023389 DOPA-like domain K08M4_RS19680 e2bb9dc1d2f2b5e0bf9e815f551acd90 254 SUPERFAMILY SSF52540 2 226 5.86E-57 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19680 e2bb9dc1d2f2b5e0bf9e815f551acd90 254 Gene3D G3DSA:3.40.50.300 2 229 9.9E-61 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19680 e2bb9dc1d2f2b5e0bf9e815f551acd90 254 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS19680 e2bb9dc1d2f2b5e0bf9e815f551acd90 254 SMART SM00382 26 213 2.6E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS19680 e2bb9dc1d2f2b5e0bf9e815f551acd90 254 Pfam PF00005 ABC transporter 18 164 8.7E-28 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS01810 d785fa8f5ac53e627e849cbda143220a 486 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 483 7.1E-155 T 05-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 K08M4_RS01810 d785fa8f5ac53e627e849cbda143220a 486 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 4 49 2.7E-17 T 05-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 K08M4_RS01810 d785fa8f5ac53e627e849cbda143220a 486 PIRSF PIRSF000774 1 486 1.1E-149 T 05-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 K08M4_RS01810 d785fa8f5ac53e627e849cbda143220a 486 PRINTS PR00045 Sigma-54 factor signature 196 213 2.0E-30 T 05-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 K08M4_RS01810 d785fa8f5ac53e627e849cbda143220a 486 PRINTS PR00045 Sigma-54 factor signature 459 477 2.0E-30 T 05-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 K08M4_RS01810 d785fa8f5ac53e627e849cbda143220a 486 PRINTS PR00045 Sigma-54 factor signature 385 397 2.0E-30 T 05-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 K08M4_RS01810 d785fa8f5ac53e627e849cbda143220a 486 PRINTS PR00045 Sigma-54 factor signature 401 412 2.0E-30 T 05-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 K08M4_RS01810 d785fa8f5ac53e627e849cbda143220a 486 Pfam PF04963 Sigma-54 factor, core binding domain 124 313 1.6E-57 T 05-07-2017 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 K08M4_RS01810 d785fa8f5ac53e627e849cbda143220a 486 Pfam PF04552 Sigma-54, DNA binding domain 326 484 1.3E-71 T 05-07-2017 IPR007634 RNA polymerase sigma factor 54, DNA-binding K08M4_RS01810 d785fa8f5ac53e627e849cbda143220a 486 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 373 392 - T 05-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 K08M4_RS01810 d785fa8f5ac53e627e849cbda143220a 486 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 464 471 - T 05-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 K08M4_RS15370 51b82740776c11128548915eb11f7b60 191 Pfam PF12464 Maltose acetyltransferase 12 61 2.4E-10 T 05-07-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 K08M4_RS15370 51b82740776c11128548915eb11f7b60 191 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 142 170 - T 05-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 K08M4_RS15370 51b82740776c11128548915eb11f7b60 191 SMART SM01266 10 62 4.4E-13 T 05-07-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 K08M4_RS15370 51b82740776c11128548915eb11f7b60 191 SUPERFAMILY SSF51161 8 188 7.62E-46 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS15370 51b82740776c11128548915eb11f7b60 191 Gene3D G3DSA:2.160.10.10 5 190 5.5E-59 T 05-07-2017 K08M4_RS15370 51b82740776c11128548915eb11f7b60 191 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 133 167 8.1E-9 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS01935 55e83441463fc48c7cc1cd1c796392e7 149 Gene3D G3DSA:3.40.50.10110 1 146 1.3E-44 T 05-07-2017 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 K08M4_RS01935 55e83441463fc48c7cc1cd1c796392e7 149 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 142 7.0E-32 T 05-07-2017 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 K08M4_RS01935 55e83441463fc48c7cc1cd1c796392e7 149 SUPERFAMILY SSF102400 1 145 5.1E-42 T 05-07-2017 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 K08M4_RS16200 4c63be6823b6339776b23fd582522cc2 443 SUPERFAMILY SSF103473 15 438 6.54E-26 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS16200 4c63be6823b6339776b23fd582522cc2 443 Gene3D G3DSA:1.20.1250.20 246 436 4.2E-5 T 05-07-2017 K08M4_RS16200 4c63be6823b6339776b23fd582522cc2 443 Gene3D G3DSA:1.20.1250.20 18 216 3.9E-13 T 05-07-2017 K08M4_RS09995 72822febf28bb8f537576791e22c5d85 101 Pfam PF08803 Putative mono-oxygenase ydhR 3 98 6.6E-41 T 05-07-2017 IPR014910 Putative monooxygenase YdhR K08M4_RS09995 72822febf28bb8f537576791e22c5d85 101 SUPERFAMILY SSF54909 1 95 1.34E-32 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel K08M4_RS21130 95587429cae513e1292f77334337c747 293 Pfam PF03547 Membrane transport protein 148 284 2.4E-11 T 05-07-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 K08M4_RS20530 a4647839d9aa0ecba83187a4f2cebb79 239 Gene3D G3DSA:3.20.20.190 4 235 7.6E-62 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 K08M4_RS20530 a4647839d9aa0ecba83187a4f2cebb79 239 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 233 2.7E-40 T 05-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 K08M4_RS20530 a4647839d9aa0ecba83187a4f2cebb79 239 SUPERFAMILY SSF51695 4 235 1.92E-63 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 K08M4_RS18645 d49897faae821fc74b700a525f1b48d9 632 SUPERFAMILY SSF56519 58 253 9.81E-54 T 05-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 K08M4_RS18645 d49897faae821fc74b700a525f1b48d9 632 Pfam PF03717 Penicillin-binding Protein dimerisation domain 65 240 2.3E-49 T 05-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 K08M4_RS18645 d49897faae821fc74b700a525f1b48d9 632 SUPERFAMILY SSF56601 255 624 3.89E-93 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS18645 d49897faae821fc74b700a525f1b48d9 632 Gene3D G3DSA:3.40.710.10 255 624 6.6E-99 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS18645 d49897faae821fc74b700a525f1b48d9 632 Pfam PF00905 Penicillin binding protein transpeptidase domain 272 618 1.7E-68 T 05-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 K08M4_RS18645 d49897faae821fc74b700a525f1b48d9 632 Gene3D G3DSA:3.90.1310.10 131 253 3.4E-39 T 05-07-2017 K08M4_RS18645 d49897faae821fc74b700a525f1b48d9 632 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 21 622 6.1E-227 T 05-07-2017 IPR017790 Penicillin-binding protein 2 GO:0016020 K08M4_RS08140 c754ec29176bd7dee24563dd0b203cf7 92 Gene3D G3DSA:1.10.10.10 38 81 3.9E-7 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS08140 c754ec29176bd7dee24563dd0b203cf7 92 SUPERFAMILY SSF88659 38 81 3.18E-7 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS08140 c754ec29176bd7dee24563dd0b203cf7 92 Pfam PF02001 Protein of unknown function DUF134 2 91 1.9E-20 T 05-07-2017 IPR002852 Uncharacterised protein family UPF0251 K08M4_RS08140 c754ec29176bd7dee24563dd0b203cf7 92 Hamap MF_00674 UPF0251 protein . 2 92 23.057 T 05-07-2017 IPR002852 Uncharacterised protein family UPF0251 K08M4_RS16860 7a97b0a26bc576d3c48a28629a7745d0 455 Pfam PF02386 Cation transport protein 49 438 1.0E-53 T 05-07-2017 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 K08M4_RS16860 7a97b0a26bc576d3c48a28629a7745d0 455 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 42 427 3.7E-121 T 05-07-2017 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 K08M4_RS02590 68083ce31561fbb4c832ff59d840d2a3 427 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 212 408 2.2E-24 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS02590 68083ce31561fbb4c832ff59d840d2a3 427 SUPERFAMILY SSF161098 175 408 9.81E-55 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS02590 68083ce31561fbb4c832ff59d840d2a3 427 SUPERFAMILY SSF160964 87 94 4.45E-13 T 05-07-2017 K08M4_RS02590 68083ce31561fbb4c832ff59d840d2a3 427 SUPERFAMILY SSF160964 122 179 4.45E-13 T 05-07-2017 K08M4_RS02590 68083ce31561fbb4c832ff59d840d2a3 427 Gene3D G3DSA:1.20.58.370 122 159 1.2E-4 T 05-07-2017 K08M4_RS02590 68083ce31561fbb4c832ff59d840d2a3 427 Gene3D G3DSA:1.10.3720.10 189 420 7.8E-59 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS04285 7d985b6a09ff95d46d24d0496ef4371a 205 SUPERFAMILY SSF52540 2 193 2.47E-40 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04285 7d985b6a09ff95d46d24d0496ef4371a 205 SMART SM00382 26 205 5.6E-7 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS04285 7d985b6a09ff95d46d24d0496ef4371a 205 Pfam PF00005 ABC transporter 18 158 5.7E-30 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS04285 7d985b6a09ff95d46d24d0496ef4371a 205 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS04285 7d985b6a09ff95d46d24d0496ef4371a 205 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 2 203 1.9E-77 T 05-07-2017 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 K08M4_RS04285 7d985b6a09ff95d46d24d0496ef4371a 205 Gene3D G3DSA:3.40.50.300 1 190 6.5E-41 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13415 974f3cc908fdd9cbc358fa6033093ea3 151 SUPERFAMILY SSF46785 11 143 2.6E-34 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS13415 974f3cc908fdd9cbc358fa6033093ea3 151 Gene3D G3DSA:1.10.10.10 10 81 9.1E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS13415 974f3cc908fdd9cbc358fa6033093ea3 151 Pfam PF01475 Ferric uptake regulator family 19 137 3.8E-19 T 05-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 K08M4_RS14100 55b058799eb1b7a5d64dd2481d07f405 476 Gene3D G3DSA:3.40.630.10 11 193 2.0E-56 T 05-07-2017 K08M4_RS14100 55b058799eb1b7a5d64dd2481d07f405 476 Gene3D G3DSA:3.40.630.10 394 475 2.0E-56 T 05-07-2017 K08M4_RS14100 55b058799eb1b7a5d64dd2481d07f405 476 SUPERFAMILY SSF55031 193 392 9.63E-21 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS14100 55b058799eb1b7a5d64dd2481d07f405 476 Pfam PF01546 Peptidase family M20/M25/M40 91 473 9.2E-22 T 05-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 K08M4_RS14100 55b058799eb1b7a5d64dd2481d07f405 476 Gene3D G3DSA:3.30.70.360 304 389 3.6E-16 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS14100 55b058799eb1b7a5d64dd2481d07f405 476 SUPERFAMILY SSF53187 9 193 1.07E-54 T 05-07-2017 K08M4_RS14100 55b058799eb1b7a5d64dd2481d07f405 476 SUPERFAMILY SSF53187 395 475 1.07E-54 T 05-07-2017 K08M4_RS14100 55b058799eb1b7a5d64dd2481d07f405 476 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 21 471 6.4E-98 T 05-07-2017 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 K08M4_RS05170 4250cd513365bb6a8afd60303e429755 32 Pfam PF16951 Putative methionine and alanine importer, small subunit 1 30 2.6E-6 T 05-07-2017 IPR031596 Putative methionine and alanine importer, small subunit K08M4_RS08365 33832f592beb2f36975185a687bb5381 1123 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 688 981 2.2E-11 T 05-07-2017 IPR033432 Glycosyl hydrolase 36, catalytic domain K08M4_RS08365 33832f592beb2f36975185a687bb5381 1123 SUPERFAMILY SSF48208 563 956 7.91E-38 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 K08M4_RS08365 33832f592beb2f36975185a687bb5381 1123 SUPERFAMILY SSF48208 983 1096 7.91E-38 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 K08M4_RS19355 a126f9700020a56f606c41baa9866840 75 Pfam PF09016 Pas factor saposin fold 3 74 1.6E-38 T 05-07-2017 IPR015106 Pas factor saposin domain K08M4_RS08590 ef58bc0621bdd67d760531bb5ed05c55 230 Pfam PF03475 3-alpha domain 173 215 1.5E-9 T 05-07-2017 IPR005163 3-alpha domain K08M4_RS08590 ef58bc0621bdd67d760531bb5ed05c55 230 SUPERFAMILY SSF50800 3 227 2.35E-70 T 05-07-2017 IPR011037 Pyruvate kinase-like, insert domain K08M4_RS08590 ef58bc0621bdd67d760531bb5ed05c55 230 Pfam PF03473 MOSC domain 49 163 6.0E-22 T 05-07-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 K08M4_RS08590 ef58bc0621bdd67d760531bb5ed05c55 230 Gene3D G3DSA:2.40.33.20 3 228 1.2E-80 T 05-07-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like K08M4_RS07010 444b51c2b6b7c1525e2d5d0308ffa8d1 198 Gene3D G3DSA:3.40.50.150 38 195 2.2E-15 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS07010 444b51c2b6b7c1525e2d5d0308ffa8d1 198 Pfam PF08241 Methyltransferase domain 40 132 3.7E-9 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 K08M4_RS07010 444b51c2b6b7c1525e2d5d0308ffa8d1 198 SUPERFAMILY SSF53335 3 196 6.66E-20 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS21790 e3f83dcbbca4be10c5a14dded04d0567 109 SUPERFAMILY SSF55248 16 108 1.7E-33 T 05-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 K08M4_RS21790 e3f83dcbbca4be10c5a14dded04d0567 109 Gene3D G3DSA:3.30.1360.20 10 108 1.8E-33 T 05-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 K08M4_RS21790 e3f83dcbbca4be10c5a14dded04d0567 109 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 17 108 1.4E-31 T 05-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 K08M4_RS21790 e3f83dcbbca4be10c5a14dded04d0567 109 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 14 109 21.477 T 05-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 K08M4_RS12420 462fae56cc51b55f50ccb3bafa48f537 158 Gene3D G3DSA:2.40.160.20 44 158 2.4E-5 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS12420 462fae56cc51b55f50ccb3bafa48f537 158 PIRSF PIRSF028680 1 158 1.6E-57 T 05-07-2017 IPR016895 Uncharacterised conserved protein UCP028680 K08M4_RS12420 462fae56cc51b55f50ccb3bafa48f537 158 SUPERFAMILY SSF56925 47 158 1.61E-5 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS07115 6dc33cbb0453fa95f2cb22e36f82de78 193 SUPERFAMILY SSF109604 5 183 1.81E-41 T 05-07-2017 K08M4_RS07115 6dc33cbb0453fa95f2cb22e36f82de78 193 Gene3D G3DSA:1.10.3210.10 3 184 5.0E-38 T 05-07-2017 IPR006674 HD domain K08M4_RS07115 6dc33cbb0453fa95f2cb22e36f82de78 193 Pfam PF13023 HD domain 14 176 2.1E-46 T 05-07-2017 IPR006674 HD domain K08M4_RS04545 87b8ea789ab8218809ba5d02a39d4108 1631 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 68 138 5.4E-25 T 05-07-2017 IPR020012 Motility protein FimV, N-terminal K08M4_RS04545 87b8ea789ab8218809ba5d02a39d4108 1631 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 1586 1628 5.8E-15 T 05-07-2017 IPR020011 Motility protein FimV, C-terminal K08M4_RS20920 3c21f5e740ea69bcbaf50ac96a3b757f 545 Pfam PF00672 HAMP domain 197 264 1.9E-14 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS20920 3c21f5e740ea69bcbaf50ac96a3b757f 545 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 410 439 2.1E-21 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS20920 3c21f5e740ea69bcbaf50ac96a3b757f 545 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 190 210 2.1E-21 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS20920 3c21f5e740ea69bcbaf50ac96a3b757f 545 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 381 408 2.1E-21 T 05-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 K08M4_RS20920 3c21f5e740ea69bcbaf50ac96a3b757f 545 SMART SM00304 214 268 3.8E-13 T 05-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 K08M4_RS20920 3c21f5e740ea69bcbaf50ac96a3b757f 545 SMART SM00283 283 544 2.3E-70 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS20920 3c21f5e740ea69bcbaf50ac96a3b757f 545 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 337 543 2.1E-51 T 05-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 K08M4_RS20920 3c21f5e740ea69bcbaf50ac96a3b757f 545 Gene3D G3DSA:1.10.287.950 298 514 5.2E-53 T 05-07-2017 K08M4_RS20920 3c21f5e740ea69bcbaf50ac96a3b757f 545 SUPERFAMILY SSF58104 236 545 1.12E-70 T 05-07-2017 K08M4_RS03130 a0589d510d5b7a0b3f8b014e8b46cec4 137 Gene3D G3DSA:3.30.300.20 2 105 2.7E-34 T 05-07-2017 IPR015946 K homology domain-like, alpha/beta K08M4_RS03130 a0589d510d5b7a0b3f8b014e8b46cec4 137 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 115 8.1E-33 T 05-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 K08M4_RS03130 a0589d510d5b7a0b3f8b014e8b46cec4 137 Pfam PF02033 Ribosome-binding factor A 7 110 5.7E-28 T 05-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 K08M4_RS03130 a0589d510d5b7a0b3f8b014e8b46cec4 137 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 118 20.141 T 05-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 K08M4_RS03130 a0589d510d5b7a0b3f8b014e8b46cec4 137 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 98 3.0E-42 T 05-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 K08M4_RS03130 a0589d510d5b7a0b3f8b014e8b46cec4 137 SUPERFAMILY SSF89919 2 105 1.7E-29 T 05-07-2017 IPR023799 Ribosome-binding factor A domain K08M4_RS01915 648c2997f2a06d4af199c7eed9274e66 265 SUPERFAMILY SSF49785 2 154 2.04E-19 T 05-07-2017 IPR008979 Galactose-binding domain-like K08M4_RS01915 648c2997f2a06d4af199c7eed9274e66 265 Gene3D G3DSA:2.60.120.260 43 128 8.6E-8 T 05-07-2017 IPR008979 Galactose-binding domain-like K08M4_RS14430 88910986fb9263859668c14001784981 65 Gene3D G3DSA:3.50.50.60 6 63 6.1E-9 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14430 88910986fb9263859668c14001784981 65 SUPERFAMILY SSF51905 8 65 2.48E-12 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS14430 88910986fb9263859668c14001784981 65 Pfam PF03486 HI0933-like protein 6 63 1.9E-30 T 05-07-2017 K08M4_RS06365 b5054786e428d6db5ca9a686c12cb598 211 Pfam PF01810 LysE type translocator 15 208 9.8E-31 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS06365 b5054786e428d6db5ca9a686c12cb598 211 PIRSF PIRSF006324 1 210 7.8E-56 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS12130 cec65296b02b8117acb66cf5e18ab225 442 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 23 235 1.0E-25 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS12130 cec65296b02b8117acb66cf5e18ab225 442 SUPERFAMILY SSF53850 11 248 2.6E-35 T 05-07-2017 K08M4_RS12130 cec65296b02b8117acb66cf5e18ab225 442 Pfam PF01464 Transglycosylase SLT domain 270 386 3.8E-15 T 05-07-2017 IPR008258 Transglycosylase SLT domain 1 K08M4_RS12130 cec65296b02b8117acb66cf5e18ab225 442 Gene3D G3DSA:3.40.190.10 93 186 1.2E-7 T 05-07-2017 K08M4_RS12130 cec65296b02b8117acb66cf5e18ab225 442 Gene3D G3DSA:1.10.530.10 263 425 9.8E-36 T 05-07-2017 K08M4_RS12130 cec65296b02b8117acb66cf5e18ab225 442 Gene3D G3DSA:3.40.190.10 9 92 2.6E-21 T 05-07-2017 K08M4_RS12130 cec65296b02b8117acb66cf5e18ab225 442 Gene3D G3DSA:3.40.190.10 207 247 2.6E-21 T 05-07-2017 K08M4_RS12130 cec65296b02b8117acb66cf5e18ab225 442 SMART SM00062 12 249 4.5E-19 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS12130 cec65296b02b8117acb66cf5e18ab225 442 SUPERFAMILY SSF53955 266 424 3.79E-32 T 05-07-2017 IPR023346 Lysozyme-like domain K08M4_RS09175 17bd1631584ce4dd80b199230906c4f0 185 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 K08M4_RS09175 17bd1631584ce4dd80b199230906c4f0 185 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 181 1.5E-55 T 05-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 K08M4_RS09175 17bd1631584ce4dd80b199230906c4f0 185 PIRSF PIRSF000847 1 184 4.4E-46 T 05-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 K08M4_RS09175 17bd1631584ce4dd80b199230906c4f0 185 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 71 1.7E-18 T 05-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 K08M4_RS08450 c3c4b5f8fa500e67419daa8d8288b9fb 350 TIGRFAM TIGR01620 hyp_HI0043: TIGR01620 family protein 69 345 7.7E-78 T 05-07-2017 IPR006507 Uncharacterised protein family UPF0283 K08M4_RS08450 c3c4b5f8fa500e67419daa8d8288b9fb 350 Pfam PF05128 Domain of unknown function (DUF697) 186 346 1.1E-50 T 05-07-2017 IPR021147 Protein of unknown function DUF697 K08M4_RS20760 6ec5597dde29e427fc9d46b2d4c38c57 218 SUPERFAMILY SSF55821 9 213 2.52E-80 T 05-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain K08M4_RS20760 6ec5597dde29e427fc9d46b2d4c38c57 218 Gene3D G3DSA:3.90.870.10 13 213 5.5E-89 T 05-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain K08M4_RS20760 6ec5597dde29e427fc9d46b2d4c38c57 218 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 12 214 41.956 T 05-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS20760 6ec5597dde29e427fc9d46b2d4c38c57 218 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 14 210 2.9E-75 T 05-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS20760 6ec5597dde29e427fc9d46b2d4c38c57 218 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 18 209 2.2E-77 T 05-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS13545 59fa44e93d7358c1a4c3a8413f7e5cff 154 Gene3D G3DSA:3.40.50.300 4 151 1.7E-52 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS13545 59fa44e93d7358c1a4c3a8413f7e5cff 154 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 133 2.4E-42 T 05-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 K08M4_RS13545 59fa44e93d7358c1a4c3a8413f7e5cff 154 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 8 139 2.6E-52 T 05-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 K08M4_RS13545 59fa44e93d7358c1a4c3a8413f7e5cff 154 SUPERFAMILY SSF52540 26 151 1.18E-24 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18835 e7d5e453858fd1c55ed3c22f6b93884f 189 Pfam PF04264 YceI-like domain 25 182 3.0E-34 T 05-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like K08M4_RS18835 e7d5e453858fd1c55ed3c22f6b93884f 189 SUPERFAMILY SSF101874 23 188 7.19E-48 T 05-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like K08M4_RS18835 e7d5e453858fd1c55ed3c22f6b93884f 189 Hamap MF_00780 Protein YceI [yceI]. 1 189 44.803 T 05-07-2017 IPR023480 Uncharacterised protein family UPF0312/YceI K08M4_RS18835 e7d5e453858fd1c55ed3c22f6b93884f 189 Gene3D G3DSA:2.40.128.110 22 188 3.8E-52 T 05-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like K08M4_RS18835 e7d5e453858fd1c55ed3c22f6b93884f 189 SMART SM00867 24 187 9.6E-60 T 05-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like K08M4_RS00880 2553894aeee9a06c862927b8c1e4496a 233 Pfam PF07356 Protein of unknown function (DUF1481) 34 228 1.5E-53 T 05-07-2017 IPR010858 Protein of unknown function DUF1481 K08M4_RS00880 2553894aeee9a06c862927b8c1e4496a 233 PIRSF PIRSF028160 1 233 1.3E-94 T 05-07-2017 IPR016872 Uncharacterised conserved protein UCP028160 K08M4_RS16800 661d7bbad7b95df89c61f5aecc5d32a1 104 SUPERFAMILY SSF47413 43 90 1.88E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS16800 661d7bbad7b95df89c61f5aecc5d32a1 104 Gene3D G3DSA:1.10.260.40 44 96 8.4E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS16800 661d7bbad7b95df89c61f5aecc5d32a1 104 Pfam PF15731 Antitoxin component of bacterial toxin-antitoxin system, MqsA 25 101 4.9E-8 T 05-07-2017 IPR032758 Antitoxin MqsA/HigA-2 K08M4_RS01370 37431c8787596cd92fe807fc98bf0131 156 TIGRFAM TIGR02444 TIGR02444: TIGR02444 family protein 13 119 9.4E-37 T 05-07-2017 IPR012659 Conserved hypothetical protein CHP02444 K08M4_RS01370 37431c8787596cd92fe807fc98bf0131 156 Pfam PF09523 Protein of unknown function (DUF2390) 15 115 4.5E-28 T 05-07-2017 IPR012659 Conserved hypothetical protein CHP02444 K08M4_RS01800 e4c4f171564e79498de0cc7f7cefa27d 152 SUPERFAMILY SSF55804 1 146 5.89E-40 T 05-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 K08M4_RS01800 e4c4f171564e79498de0cc7f7cefa27d 152 Gene3D G3DSA:3.40.930.10 1 147 2.7E-44 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS01800 e4c4f171564e79498de0cc7f7cefa27d 152 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 51 67 - T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS01800 e4c4f171564e79498de0cc7f7cefa27d 152 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 9 145 6.6E-37 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS01800 e4c4f171564e79498de0cc7f7cefa27d 152 TIGRFAM TIGR01419 nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN 2 145 3.7E-50 T 05-07-2017 IPR006320 Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN GO:0008982|GO:0009401 K08M4_RS01805 b3e3f7240a6815ca927a1e58a6e41fc9 95 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 95 3.6E-33 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 K08M4_RS01805 b3e3f7240a6815ca927a1e58a6e41fc9 95 SUPERFAMILY SSF69754 1 95 1.57E-34 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 K08M4_RS01805 b3e3f7240a6815ca927a1e58a6e41fc9 95 Gene3D G3DSA:3.30.160.100 1 95 7.7E-38 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 K08M4_RS01805 b3e3f7240a6815ca927a1e58a6e41fc9 95 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 92 2.1E-28 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 K08M4_RS06900 e0b6e0f9fefe80d481e8c4c07f09ef46 306 SUPERFAMILY SSF53850 89 303 3.98E-36 T 05-07-2017 K08M4_RS06900 e0b6e0f9fefe80d481e8c4c07f09ef46 306 Pfam PF03466 LysR substrate binding domain 103 304 2.6E-18 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS06900 e0b6e0f9fefe80d481e8c4c07f09ef46 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.7E-12 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS06900 e0b6e0f9fefe80d481e8c4c07f09ef46 306 SUPERFAMILY SSF46785 2 84 1.14E-14 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06900 e0b6e0f9fefe80d481e8c4c07f09ef46 306 Gene3D G3DSA:3.40.190.10 261 304 1.6E-5 T 05-07-2017 K08M4_RS06900 e0b6e0f9fefe80d481e8c4c07f09ef46 306 Gene3D G3DSA:3.40.190.10 89 179 1.3E-11 T 05-07-2017 K08M4_RS06900 e0b6e0f9fefe80d481e8c4c07f09ef46 306 Gene3D G3DSA:1.10.10.10 1 85 9.1E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06900 e0b6e0f9fefe80d481e8c4c07f09ef46 306 Gene3D G3DSA:3.40.190.10 180 260 1.2E-14 T 05-07-2017 K08M4_RS18745 d74acad81b4331f1639cf6be02a37354 302 Pfam PF13737 Transposase DDE domain 20 130 2.1E-43 T 05-07-2017 IPR025668 Transposase DDE domain K08M4_RS05240 e0d3b7c71a099c29bd8bb26b08b604ce 644 SUPERFAMILY SSF52540 75 145 1.72E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05240 e0d3b7c71a099c29bd8bb26b08b604ce 644 SUPERFAMILY SSF52540 236 368 1.72E-17 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05240 e0d3b7c71a099c29bd8bb26b08b604ce 644 SMART SM00763 19 380 1.6E-212 T 05-07-2017 IPR013153 PrkA AAA domain K08M4_RS05240 e0d3b7c71a099c29bd8bb26b08b604ce 644 PIRSF PIRSF000549 1 644 3.5E-285 T 05-07-2017 IPR016230 Serine-protein kinase, PrkA GO:0004672 K08M4_RS05240 e0d3b7c71a099c29bd8bb26b08b604ce 644 Gene3D G3DSA:3.40.50.300 74 170 3.0E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05240 e0d3b7c71a099c29bd8bb26b08b604ce 644 Gene3D G3DSA:3.40.50.300 243 329 3.0E-11 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05240 e0d3b7c71a099c29bd8bb26b08b604ce 644 Pfam PF08298 PrkA AAA domain 20 380 3.8E-172 T 05-07-2017 IPR013153 PrkA AAA domain K08M4_RS05240 e0d3b7c71a099c29bd8bb26b08b604ce 644 Pfam PF06798 PrkA serine protein kinase C-terminal domain 383 636 1.4E-73 T 05-07-2017 IPR010650 PrkA C-terminal domain K08M4_RS06615 b75986653be5f36ab39d854eee2feab6 541 Pfam PF00753 Metallo-beta-lactamase superfamily 143 242 6.2E-10 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS06615 b75986653be5f36ab39d854eee2feab6 541 SUPERFAMILY SSF56281 126 403 6.55E-34 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS06615 b75986653be5f36ab39d854eee2feab6 541 Gene3D G3DSA:3.60.15.10 126 414 3.4E-35 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS06615 b75986653be5f36ab39d854eee2feab6 541 SMART SM00849 142 378 0.0073 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS00200 d59b284d152de925c719957f81de5d8b 421 Gene3D G3DSA:1.20.1250.20 35 213 6.7E-33 T 05-07-2017 K08M4_RS00200 d59b284d152de925c719957f81de5d8b 421 SUPERFAMILY SSF103473 24 406 2.22E-61 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS00200 d59b284d152de925c719957f81de5d8b 421 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 32 398 2.0E-69 T 05-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 K08M4_RS00200 d59b284d152de925c719957f81de5d8b 421 ProSitePatterns PS00216 Sugar transport proteins signature 1. 89 105 - T 05-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 K08M4_RS00200 d59b284d152de925c719957f81de5d8b 421 Pfam PF07690 Major Facilitator Superfamily 40 376 8.2E-47 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS00200 d59b284d152de925c719957f81de5d8b 421 Gene3D G3DSA:1.20.1250.20 224 405 3.1E-9 T 05-07-2017 K08M4_RS20540 f430f263fa341f2ca4e987652ef4f40c 257 SUPERFAMILY SSF141523 121 255 9.29E-24 T 05-07-2017 K08M4_RS20540 f430f263fa341f2ca4e987652ef4f40c 257 Gene3D G3DSA:2.40.440.10 120 255 6.3E-18 T 05-07-2017 K08M4_RS20540 f430f263fa341f2ca4e987652ef4f40c 257 Pfam PF03734 L,D-transpeptidase catalytic domain 122 255 4.0E-18 T 05-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 K08M4_RS10285 288e5d08030ce1e1c00c68ecd45d5ed6 307 SMART SM00978 176 307 4.1E-37 T 05-07-2017 IPR007379 Tim44-like domain K08M4_RS10285 288e5d08030ce1e1c00c68ecd45d5ed6 307 SUPERFAMILY SSF54427 186 306 1.27E-15 T 05-07-2017 IPR032710 NTF2-like domain K08M4_RS10285 288e5d08030ce1e1c00c68ecd45d5ed6 307 Pfam PF04280 Tim44-like domain 185 306 7.7E-16 T 05-07-2017 IPR007379 Tim44-like domain K08M4_RS05030 9f6298cdf58fb5805ddaf2833310168d 530 Hamap MF_01599 Na(+)/H(+) antiporter NhaB [nhaB]. 1 530 374.896 T 05-07-2017 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 K08M4_RS05030 9f6298cdf58fb5805ddaf2833310168d 530 TIGRFAM TIGR00774 NhaB: Na+/H+ antiporter NhaB 1 515 9.9E-297 T 05-07-2017 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 K08M4_RS05030 9f6298cdf58fb5805ddaf2833310168d 530 Pfam PF06450 Bacterial Na+/H+ antiporter B (NhaB) 1 516 1.8E-290 T 05-07-2017 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 K08M4_RS19335 cdc76b123fae3d93ac20eb84081ae0a1 128 SUPERFAMILY SSF46626 13 115 1.63E-18 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19335 cdc76b123fae3d93ac20eb84081ae0a1 128 Pfam PF00034 Cytochrome c 38 109 2.0E-5 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19335 cdc76b123fae3d93ac20eb84081ae0a1 128 Gene3D G3DSA:1.10.760.10 37 112 3.8E-21 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS15070 48e8b5b13655cd9d496560865ab503ae 210 Gene3D G3DSA:3.40.50.1820 5 205 3.0E-22 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS15070 48e8b5b13655cd9d496560865ab503ae 210 SUPERFAMILY SSF53474 3 188 3.31E-16 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS05715 45374bfd85d5fc175c6801b4eba16885 303 Gene3D G3DSA:1.10.10.10 1 87 3.0E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05715 45374bfd85d5fc175c6801b4eba16885 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.2E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS05715 45374bfd85d5fc175c6801b4eba16885 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.2E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS05715 45374bfd85d5fc175c6801b4eba16885 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.2E-7 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS05715 45374bfd85d5fc175c6801b4eba16885 303 Pfam PF03466 LysR substrate binding domain 89 292 5.5E-38 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS05715 45374bfd85d5fc175c6801b4eba16885 303 SUPERFAMILY SSF46785 1 112 3.3E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05715 45374bfd85d5fc175c6801b4eba16885 303 SUPERFAMILY SSF53850 89 296 1.99E-36 T 05-07-2017 K08M4_RS05715 45374bfd85d5fc175c6801b4eba16885 303 Gene3D G3DSA:3.40.190.10 180 260 6.4E-17 T 05-07-2017 K08M4_RS05715 45374bfd85d5fc175c6801b4eba16885 303 Gene3D G3DSA:3.40.190.10 90 179 5.4E-11 T 05-07-2017 K08M4_RS05715 45374bfd85d5fc175c6801b4eba16885 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.5E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS08900 fd652ae60cb0c1a4aa56c938240e4af1 139 Pfam PF04940 Sensors of blue-light using FAD 3 94 5.7E-29 T 05-07-2017 IPR007024 BLUF domain GO:0009882|GO:0071949 K08M4_RS08900 fd652ae60cb0c1a4aa56c938240e4af1 139 SMART SM01034 3 95 3.6E-38 T 05-07-2017 IPR007024 BLUF domain GO:0009882|GO:0071949 K08M4_RS08900 fd652ae60cb0c1a4aa56c938240e4af1 139 SUPERFAMILY SSF54975 3 134 2.35E-39 T 05-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 K08M4_RS04015 ee03c1f2079352c23cc8501f5e70b09b 141 SUPERFAMILY SSF140566 1 113 3.92E-21 T 05-07-2017 IPR007809 FlgN-like protein GO:0005515|GO:0044780 K08M4_RS04015 ee03c1f2079352c23cc8501f5e70b09b 141 Gene3D G3DSA:1.20.58.300 1 113 4.0E-22 T 05-07-2017 IPR007809 FlgN-like protein GO:0005515|GO:0044780 K08M4_RS04015 ee03c1f2079352c23cc8501f5e70b09b 141 Pfam PF05130 FlgN protein 2 131 2.0E-25 T 05-07-2017 IPR007809 FlgN-like protein GO:0005515|GO:0044780 K08M4_RS20575 ecf14c4547959102b2fa3eedbec0b494 390 SUPERFAMILY SSF50494 46 253 4.57E-15 T 05-07-2017 IPR009003 Peptidase S1, PA clan K08M4_RS20575 ecf14c4547959102b2fa3eedbec0b494 390 Pfam PF00089 Trypsin 35 220 3.0E-7 T 05-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 K08M4_RS20575 ecf14c4547959102b2fa3eedbec0b494 390 Gene3D G3DSA:2.40.10.10 49 253 1.5E-8 T 05-07-2017 K08M4_RS12980 d050028e23b5559ba2b2d207aa6fa9e1 267 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 1 267 46.345 T 05-07-2017 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 K08M4_RS12980 d050028e23b5559ba2b2d207aa6fa9e1 267 SUPERFAMILY SSF56300 4 252 6.53E-53 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS12980 d050028e23b5559ba2b2d207aa6fa9e1 267 PIRSF PIRSF000903 1 267 1.5E-116 T 05-07-2017 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 K08M4_RS12980 d050028e23b5559ba2b2d207aa6fa9e1 267 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 2 266 2.0E-112 T 05-07-2017 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 K08M4_RS12980 d050028e23b5559ba2b2d207aa6fa9e1 267 Gene3D G3DSA:3.60.21.10 167 265 5.7E-55 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS12980 d050028e23b5559ba2b2d207aa6fa9e1 267 Gene3D G3DSA:3.60.21.10 4 130 5.7E-55 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS12980 d050028e23b5559ba2b2d207aa6fa9e1 267 Pfam PF00149 Calcineurin-like phosphoesterase 5 151 2.2E-12 T 05-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 K08M4_RS03080 9756613b4438f9f4f36959b2851d0689 656 Gene3D G3DSA:1.10.8.60 334 407 4.1E-27 T 05-07-2017 K08M4_RS03080 9756613b4438f9f4f36959b2851d0689 656 SUPERFAMILY SSF52540 145 393 8.03E-71 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03080 9756613b4438f9f4f36959b2851d0689 656 SUPERFAMILY SSF140990 404 598 7.85E-74 T 05-07-2017 K08M4_RS03080 9756613b4438f9f4f36959b2851d0689 656 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 621 37.122 T 05-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 K08M4_RS03080 9756613b4438f9f4f36959b2851d0689 656 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 102 595 5.8E-241 T 05-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 K08M4_RS03080 9756613b4438f9f4f36959b2851d0689 656 SMART SM00382 186 325 1.9E-26 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS03080 9756613b4438f9f4f36959b2851d0689 656 ProSitePatterns PS00674 AAA-protein family signature. 293 311 - T 05-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 K08M4_RS03080 9756613b4438f9f4f36959b2851d0689 656 Pfam PF01434 Peptidase family M41 384 593 1.3E-80 T 05-07-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 K08M4_RS03080 9756613b4438f9f4f36959b2851d0689 656 Gene3D G3DSA:3.40.50.300 149 333 3.5E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03080 9756613b4438f9f4f36959b2851d0689 656 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 190 322 1.9E-46 T 05-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 K08M4_RS03080 9756613b4438f9f4f36959b2851d0689 656 Pfam PF06480 FtsH Extracellular 5 94 8.3E-13 T 05-07-2017 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 K08M4_RS09135 7d607022d97c2b2190a1d9bb76134fe7 180 Pfam PF07603 Protein of unknown function (DUF1566) 43 164 4.0E-21 T 05-07-2017 IPR011460 Protein of unknown function DUF1566 K08M4_RS06915 ba20da3af742b530ffcd5b9424e80088 164 Pfam PF00583 Acetyltransferase (GNAT) family 63 141 1.0E-13 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS06915 ba20da3af742b530ffcd5b9424e80088 164 Gene3D G3DSA:3.40.630.30 25 156 6.1E-23 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS06915 ba20da3af742b530ffcd5b9424e80088 164 SUPERFAMILY SSF55729 25 156 6.1E-22 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS05730 bdc0b1c94093a0fa3329387518045e2b 98 SUPERFAMILY SSF54909 1 98 3.4E-32 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel K08M4_RS05730 bdc0b1c94093a0fa3329387518045e2b 98 Gene3D G3DSA:3.30.70.1060 1 98 5.7E-38 T 05-07-2017 K08M4_RS05730 bdc0b1c94093a0fa3329387518045e2b 98 Pfam PF03795 YCII-related domain 1 95 1.3E-28 T 05-07-2017 IPR005545 YCII-related K08M4_RS15460 a7dc25cbb58ae977eb01e18e9a339ac3 395 Pfam PF07690 Major Facilitator Superfamily 9 320 3.3E-43 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS15460 a7dc25cbb58ae977eb01e18e9a339ac3 395 Gene3D G3DSA:1.20.1250.20 5 184 4.2E-28 T 05-07-2017 K08M4_RS15460 a7dc25cbb58ae977eb01e18e9a339ac3 395 PRINTS PR01035 Tetracycline resistance protein signature 40 59 1.5E-5 T 05-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 K08M4_RS15460 a7dc25cbb58ae977eb01e18e9a339ac3 395 PRINTS PR01035 Tetracycline resistance protein signature 98 119 1.5E-5 T 05-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 K08M4_RS15460 a7dc25cbb58ae977eb01e18e9a339ac3 395 PRINTS PR01035 Tetracycline resistance protein signature 158 178 1.5E-5 T 05-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 K08M4_RS15460 a7dc25cbb58ae977eb01e18e9a339ac3 395 PRINTS PR01035 Tetracycline resistance protein signature 10 26 1.5E-5 T 05-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 K08M4_RS15460 a7dc25cbb58ae977eb01e18e9a339ac3 395 Gene3D G3DSA:1.20.1250.20 199 386 1.1E-21 T 05-07-2017 K08M4_RS15460 a7dc25cbb58ae977eb01e18e9a339ac3 395 SUPERFAMILY SSF103473 3 380 2.49E-65 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS09915 46affd762ec64d6adb6f4634cb7331d5 138 Gene3D G3DSA:3.10.580.10 1 132 6.0E-28 T 05-07-2017 K08M4_RS09915 46affd762ec64d6adb6f4634cb7331d5 138 SMART SM00116 80 127 2.3E-6 T 05-07-2017 IPR000644 CBS domain K08M4_RS09915 46affd762ec64d6adb6f4634cb7331d5 138 SMART SM00116 13 61 0.0069 T 05-07-2017 IPR000644 CBS domain K08M4_RS09915 46affd762ec64d6adb6f4634cb7331d5 138 SUPERFAMILY SSF54631 1 126 1.89E-33 T 05-07-2017 K08M4_RS09915 46affd762ec64d6adb6f4634cb7331d5 138 Pfam PF00571 CBS domain 73 126 3.0E-10 T 05-07-2017 IPR000644 CBS domain K08M4_RS09915 46affd762ec64d6adb6f4634cb7331d5 138 Pfam PF00571 CBS domain 6 61 9.9E-11 T 05-07-2017 IPR000644 CBS domain K08M4_RS10010 d35c9f519a2a70cedba5e2cbd87ccb15 571 Gene3D G3DSA:2.30.40.10 506 567 1.1E-10 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS10010 d35c9f519a2a70cedba5e2cbd87ccb15 571 Gene3D G3DSA:2.30.40.10 32 107 9.5E-16 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS10010 d35c9f519a2a70cedba5e2cbd87ccb15 571 SUPERFAMILY SSF51556 179 522 4.81E-32 T 05-07-2017 IPR032466 Metal-dependent hydrolase K08M4_RS10010 d35c9f519a2a70cedba5e2cbd87ccb15 571 SUPERFAMILY SSF51556 86 100 4.81E-32 T 05-07-2017 IPR032466 Metal-dependent hydrolase K08M4_RS10010 d35c9f519a2a70cedba5e2cbd87ccb15 571 Pfam PF07969 Amidohydrolase family 75 562 1.5E-90 T 05-07-2017 IPR013108 Amidohydrolase 3 K08M4_RS10010 d35c9f519a2a70cedba5e2cbd87ccb15 571 SUPERFAMILY SSF51338 521 565 1.77E-18 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS10010 d35c9f519a2a70cedba5e2cbd87ccb15 571 SUPERFAMILY SSF51338 28 87 1.77E-18 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS10010 d35c9f519a2a70cedba5e2cbd87ccb15 571 Gene3D G3DSA:3.20.20.140 234 505 2.0E-20 T 05-07-2017 K08M4_RS08855 b80b4a622dfe3612f563fa3e06712ff1 363 Pfam PF14319 Transposase zinc-binding domain 17 114 7.4E-32 T 05-07-2017 IPR026889 Transposase zinc-binding domain K08M4_RS08855 b80b4a622dfe3612f563fa3e06712ff1 363 Pfam PF04986 Putative transposase 140 306 1.9E-43 T 05-07-2017 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 K08M4_RS07210 b80b4a622dfe3612f563fa3e06712ff1 363 Pfam PF14319 Transposase zinc-binding domain 17 114 7.4E-32 T 05-07-2017 IPR026889 Transposase zinc-binding domain K08M4_RS07210 b80b4a622dfe3612f563fa3e06712ff1 363 Pfam PF04986 Putative transposase 140 306 1.9E-43 T 05-07-2017 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 K08M4_RS07290 fb910072fb03fcd70d2cd8d7bfac1d83 506 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 13 485 1.3E-85 T 05-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 K08M4_RS07290 fb910072fb03fcd70d2cd8d7bfac1d83 506 SUPERFAMILY SSF56954 59 487 1.96E-90 T 05-07-2017 K08M4_RS07290 fb910072fb03fcd70d2cd8d7bfac1d83 506 SUPERFAMILY SSF56954 5 36 1.96E-90 T 05-07-2017 K08M4_RS07290 fb910072fb03fcd70d2cd8d7bfac1d83 506 Gene3D G3DSA:1.20.1600.10 373 487 1.6E-77 T 05-07-2017 K08M4_RS07290 fb910072fb03fcd70d2cd8d7bfac1d83 506 Gene3D G3DSA:1.20.1600.10 162 335 1.6E-77 T 05-07-2017 K08M4_RS07290 fb910072fb03fcd70d2cd8d7bfac1d83 506 Gene3D G3DSA:1.20.1600.10 57 94 1.6E-77 T 05-07-2017 K08M4_RS07290 fb910072fb03fcd70d2cd8d7bfac1d83 506 Gene3D G3DSA:2.20.200.10 336 368 4.9E-7 T 05-07-2017 K08M4_RS07290 fb910072fb03fcd70d2cd8d7bfac1d83 506 Gene3D G3DSA:2.20.200.10 145 161 4.9E-7 T 05-07-2017 K08M4_RS07290 fb910072fb03fcd70d2cd8d7bfac1d83 506 Pfam PF02321 Outer membrane efflux protein 302 484 2.0E-24 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS07290 fb910072fb03fcd70d2cd8d7bfac1d83 506 Pfam PF02321 Outer membrane efflux protein 68 274 1.5E-14 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS11245 c7eedeab5c0a3d0b68bfa982578e9d0a 127 Hamap MF_01519 UPF0325 protein YaeH [yaeH]. 1 127 30.339 T 05-07-2017 IPR020911 Uncharacterised protein family UPF0325 K08M4_RS11245 c7eedeab5c0a3d0b68bfa982578e9d0a 127 Pfam PF11944 Protein of unknown function (DUF3461) 1 126 2.0E-55 T 05-07-2017 IPR020911 Uncharacterised protein family UPF0325 K08M4_RS11245 c7eedeab5c0a3d0b68bfa982578e9d0a 127 ProDom PD080106 UPF0325 YAEH STRUCTURAL ECA1027 VV11856 YPTB3007 PBPRA2971 VV2560 VF1965 VC2264 1 126 8.0E-59 T 05-07-2017 IPR020911 Uncharacterised protein family UPF0325 K08M4_RS08530 ca71b506e1c14dac1faf09d6080a5b95 464 SUPERFAMILY SSF52096 103 221 2.09E-7 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS17095 7f1b8ed1d4325d3d7a0b95e7aa7ee91e 273 Gene3D G3DSA:1.10.260.40 2 70 2.5E-12 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS17095 7f1b8ed1d4325d3d7a0b95e7aa7ee91e 273 SUPERFAMILY SSF47413 3 73 1.38E-8 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS17095 7f1b8ed1d4325d3d7a0b95e7aa7ee91e 273 SMART SM00530 9 72 0.003 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 K08M4_RS18030 cf2628bb2a9acd6d7012cef43b8d6df4 107 SUPERFAMILY SSF50022 1 106 7.59E-34 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 K08M4_RS18030 cf2628bb2a9acd6d7012cef43b8d6df4 107 Pfam PF13806 Rieske-like [2Fe-2S] domain 3 106 1.7E-39 T 05-07-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 K08M4_RS18030 cf2628bb2a9acd6d7012cef43b8d6df4 107 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 4 106 8.3E-34 T 05-07-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 K08M4_RS18030 cf2628bb2a9acd6d7012cef43b8d6df4 107 Gene3D G3DSA:2.102.10.10 2 106 3.5E-39 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 K08M4_RS05060 2dcff316d7e4ccfedcc76ee0283a0c0e 727 Pfam PF05170 AsmA family 2 614 4.0E-116 T 05-07-2017 IPR007844 AsmA K08M4_RS02845 1ddac5a4b9b2602d53b99c318b87ebb0 176 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 7 172 2.5E-72 T 05-07-2017 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 K08M4_RS02845 1ddac5a4b9b2602d53b99c318b87ebb0 176 Pfam PF00156 Phosphoribosyl transferase domain 12 159 6.6E-27 T 05-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 K08M4_RS02845 1ddac5a4b9b2602d53b99c318b87ebb0 176 Gene3D G3DSA:3.40.50.2020 2 175 1.2E-77 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS02845 1ddac5a4b9b2602d53b99c318b87ebb0 176 SUPERFAMILY SSF53271 2 171 5.64E-54 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS09980 8ff87426a2ffec1d5800a89b1cfc7ee0 371 Pfam PF13533 Biotin-lipoyl like 79 120 4.9E-8 T 05-07-2017 K08M4_RS09980 8ff87426a2ffec1d5800a89b1cfc7ee0 371 SUPERFAMILY SSF111369 61 276 3.01E-17 T 05-07-2017 K08M4_RS09980 8ff87426a2ffec1d5800a89b1cfc7ee0 371 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 53 365 3.0E-52 T 05-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 K08M4_RS09980 8ff87426a2ffec1d5800a89b1cfc7ee0 371 Gene3D G3DSA:2.40.50.100 73 106 1.6E-14 T 05-07-2017 K08M4_RS09980 8ff87426a2ffec1d5800a89b1cfc7ee0 371 Gene3D G3DSA:2.40.50.100 181 213 1.6E-14 T 05-07-2017 K08M4_RS01050 e45d6b65e3846d9219756f896be576a6 159 SUPERFAMILY SSF75217 2 157 1.37E-42 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases K08M4_RS01050 e45d6b65e3846d9219756f896be576a6 159 PIRSF PIRSF029256 1 159 1.6E-64 T 05-07-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 K08M4_RS01050 e45d6b65e3846d9219756f896be576a6 159 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 156 31.788 T 05-07-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 K08M4_RS01050 e45d6b65e3846d9219756f896be576a6 159 Pfam PF00588 SpoU rRNA Methylase family 3 146 2.8E-34 T 05-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 K08M4_RS01050 e45d6b65e3846d9219756f896be576a6 159 Gene3D G3DSA:3.40.1280.10 1 158 1.6E-63 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal K08M4_RS03050 d677beca04b6e6fec35cde705df1f5cd 281 Pfam PF01769 Divalent cation transporter 142 272 6.8E-27 T 05-07-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 K08M4_RS03050 d677beca04b6e6fec35cde705df1f5cd 281 SUPERFAMILY SSF161093 100 278 1.22E-43 T 05-07-2017 K08M4_RS03050 d677beca04b6e6fec35cde705df1f5cd 281 Gene3D G3DSA:1.10.357.20 99 279 9.1E-52 T 05-07-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 K08M4_RS12150 86a737f193a9c19a28df30b6931f2a77 173 Pfam PF01931 Protein of unknown function DUF84 7 166 6.9E-58 T 05-07-2017 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 K08M4_RS12150 86a737f193a9c19a28df30b6931f2a77 173 Gene3D G3DSA:3.90.950.10 2 170 3.5E-64 T 05-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like K08M4_RS12150 86a737f193a9c19a28df30b6931f2a77 173 TIGRFAM TIGR00258 TIGR00258: inosine/xanthosine triphosphatase 6 170 1.1E-46 T 05-07-2017 IPR002786 Non-canonical purine NTP phosphatase K08M4_RS12150 86a737f193a9c19a28df30b6931f2a77 173 SUPERFAMILY SSF52972 2 171 3.36E-61 T 05-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like K08M4_RS12150 86a737f193a9c19a28df30b6931f2a77 173 Hamap MF_00648 Non-canonical purine NTP phosphatase. 2 171 30.842 T 05-07-2017 IPR002786 Non-canonical purine NTP phosphatase K08M4_RS19860 3377b1a128191352b2efa1ea60cee1b1 342 Pfam PF13551 Winged helix-turn helix 28 84 2.2E-8 T 05-07-2017 K08M4_RS19860 3377b1a128191352b2efa1ea60cee1b1 342 Pfam PF13358 DDE superfamily endonuclease 163 306 5.0E-35 T 05-07-2017 K08M4_RS19860 3377b1a128191352b2efa1ea60cee1b1 342 Pfam PF13592 Winged helix-turn helix 94 150 7.3E-18 T 05-07-2017 IPR025959 Winged helix-turn helix domain K08M4_RS19860 3377b1a128191352b2efa1ea60cee1b1 342 Gene3D G3DSA:1.10.10.10 34 64 6.3E-4 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19860 3377b1a128191352b2efa1ea60cee1b1 342 SUPERFAMILY SSF46689 11 127 2.09E-24 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS19860 3377b1a128191352b2efa1ea60cee1b1 342 SUPERFAMILY SSF53098 216 310 5.92E-7 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS11155 1c20c2a0822cbf770b5930f4cb92d06e 206 Gene3D G3DSA:3.30.420.10 20 161 2.0E-47 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS11155 1c20c2a0822cbf770b5930f4cb92d06e 206 SUPERFAMILY SSF53098 14 204 8.65E-70 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS11155 1c20c2a0822cbf770b5930f4cb92d06e 206 Hamap MF_00052_B Ribonuclease HII [rnhB]. 20 199 37.437 T 05-07-2017 IPR022898 Ribonuclease HII GO:0004523 K08M4_RS11155 1c20c2a0822cbf770b5930f4cb92d06e 206 Pfam PF01351 Ribonuclease HII 22 198 1.4E-38 T 05-07-2017 IPR024567 Ribonuclease HII/HIII domain K08M4_RS12250 c5150d6405589f8bcebd80664bd67be6 520 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 5 512 1.9E-138 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ K08M4_RS12250 c5150d6405589f8bcebd80664bd67be6 520 PRINTS PR01806 Virulence factor MviN signature 54 70 3.0E-76 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ K08M4_RS12250 c5150d6405589f8bcebd80664bd67be6 520 PRINTS PR01806 Virulence factor MviN signature 35 54 3.0E-76 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ K08M4_RS12250 c5150d6405589f8bcebd80664bd67be6 520 PRINTS PR01806 Virulence factor MviN signature 142 166 3.0E-76 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ K08M4_RS12250 c5150d6405589f8bcebd80664bd67be6 520 PRINTS PR01806 Virulence factor MviN signature 268 294 3.0E-76 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ K08M4_RS12250 c5150d6405589f8bcebd80664bd67be6 520 PRINTS PR01806 Virulence factor MviN signature 166 187 3.0E-76 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ K08M4_RS12250 c5150d6405589f8bcebd80664bd67be6 520 PRINTS PR01806 Virulence factor MviN signature 418 435 3.0E-76 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ K08M4_RS12250 c5150d6405589f8bcebd80664bd67be6 520 PRINTS PR01806 Virulence factor MviN signature 366 385 3.0E-76 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ K08M4_RS12250 c5150d6405589f8bcebd80664bd67be6 520 PIRSF PIRSF002869 1 519 2.6E-149 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ K08M4_RS12250 c5150d6405589f8bcebd80664bd67be6 520 Pfam PF03023 MviN-like protein 30 480 3.9E-145 T 05-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ K08M4_RS11270 5ca44719836d685e30f6b328f5fb9438 172 SUPERFAMILY SSF55729 1 146 4.53E-21 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS11270 5ca44719836d685e30f6b328f5fb9438 172 Gene3D G3DSA:3.40.630.30 1 154 2.9E-23 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS11270 5ca44719836d685e30f6b328f5fb9438 172 Pfam PF13302 Acetyltransferase (GNAT) domain 7 139 1.1E-15 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS18005 44229ebcda101e327e14978e739e44c5 194 Gene3D G3DSA:2.102.10.10 54 177 5.3E-22 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 K08M4_RS18005 44229ebcda101e327e14978e739e44c5 194 SUPERFAMILY SSF50022 18 174 8.85E-18 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 K08M4_RS18005 44229ebcda101e327e14978e739e44c5 194 Pfam PF00355 Rieske [2Fe-2S] domain 62 161 1.4E-7 T 05-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 K08M4_RS18005 44229ebcda101e327e14978e739e44c5 194 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 17 38 2.6E-5 T 05-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal K08M4_RS18005 44229ebcda101e327e14978e739e44c5 194 TIGRFAM TIGR02694 arsenite_ox_S: arsenite oxidase, small subunit 55 188 5.4E-34 T 05-07-2017 IPR014067 Arsenite oxidase, small subunit MetaCyc: PWY-7429 K08M4_RS12485 137d127e69a8b1fda8945f94b31fce09 231 Gene3D G3DSA:3.40.50.1580 1 230 2.5E-78 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 K08M4_RS12485 137d127e69a8b1fda8945f94b31fce09 231 Pfam PF01048 Phosphorylase superfamily 2 227 3.5E-49 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 K08M4_RS12485 137d127e69a8b1fda8945f94b31fce09 231 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 230 47.126 T 05-07-2017 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 K08M4_RS12485 137d127e69a8b1fda8945f94b31fce09 231 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 228 1.0E-97 T 05-07-2017 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 K08M4_RS12485 137d127e69a8b1fda8945f94b31fce09 231 SUPERFAMILY SSF53167 1 230 1.44E-71 T 05-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 K08M4_RS18040 c751884f317e04a30cbcbb474d23160f 258 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 95 128 - T 05-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 K08M4_RS18040 c751884f317e04a30cbcbb474d23160f 258 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 15 248 2.1E-94 T 05-07-2017 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 K08M4_RS18040 c751884f317e04a30cbcbb474d23160f 258 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 18 227 3.0E-49 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS18040 c751884f317e04a30cbcbb474d23160f 258 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 20 34 - T 05-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 K08M4_RS18040 c751884f317e04a30cbcbb474d23160f 258 SUPERFAMILY SSF53790 11 255 5.76E-79 T 05-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS18040 c751884f317e04a30cbcbb474d23160f 258 Gene3D G3DSA:3.30.950.10 131 257 8.4E-49 T 05-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS18040 c751884f317e04a30cbcbb474d23160f 258 Gene3D G3DSA:3.40.1010.10 14 130 1.6E-43 T 05-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 K08M4_RS03085 0abe908bc1dc8dfb2c06fa5528578841 276 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 51 64 - T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS03085 0abe908bc1dc8dfb2c06fa5528578841 276 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 17 271 3.2E-105 T 05-07-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 K08M4_RS03085 0abe908bc1dc8dfb2c06fa5528578841 276 Gene3D G3DSA:3.20.20.20 12 274 1.3E-111 T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS03085 0abe908bc1dc8dfb2c06fa5528578841 276 Pfam PF00809 Pterin binding enzyme 18 257 3.1E-92 T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS03085 0abe908bc1dc8dfb2c06fa5528578841 276 SUPERFAMILY SSF51717 5 274 1.7E-107 T 05-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS03085 0abe908bc1dc8dfb2c06fa5528578841 276 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 17 32 - T 05-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 K08M4_RS01195 ddc769bec792f6102b6fdb454b446fe3 378 Hamap MF_01108 Acetylornithine deacetylase [argE]. 1 378 64.227 T 05-07-2017 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 K08M4_RS01195 ddc769bec792f6102b6fdb454b446fe3 378 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 106 143 - T 05-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 K08M4_RS01195 ddc769bec792f6102b6fdb454b446fe3 378 SUPERFAMILY SSF55031 177 291 9.42E-23 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS01195 ddc769bec792f6102b6fdb454b446fe3 378 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 8 371 1.7E-126 T 05-07-2017 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 K08M4_RS01195 ddc769bec792f6102b6fdb454b446fe3 378 Gene3D G3DSA:3.30.70.360 186 287 1.6E-26 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS01195 ddc769bec792f6102b6fdb454b446fe3 378 Pfam PF01546 Peptidase family M20/M25/M40 72 374 6.1E-32 T 05-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 K08M4_RS01195 ddc769bec792f6102b6fdb454b446fe3 378 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 71 80 - T 05-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 K08M4_RS01195 ddc769bec792f6102b6fdb454b446fe3 378 SUPERFAMILY SSF53187 3 176 4.86E-56 T 05-07-2017 K08M4_RS01195 ddc769bec792f6102b6fdb454b446fe3 378 SUPERFAMILY SSF53187 301 377 4.86E-56 T 05-07-2017 K08M4_RS01195 ddc769bec792f6102b6fdb454b446fe3 378 Pfam PF07687 Peptidase dimerisation domain 174 285 2.1E-25 T 05-07-2017 IPR011650 Peptidase M20, dimerisation domain K08M4_RS01195 ddc769bec792f6102b6fdb454b446fe3 378 Gene3D G3DSA:3.40.630.10 319 377 6.9E-61 T 05-07-2017 K08M4_RS01195 ddc769bec792f6102b6fdb454b446fe3 378 Gene3D G3DSA:3.40.630.10 4 185 6.9E-61 T 05-07-2017 K08M4_RS04245 a32e847bbab607c39626a0437bfa7f5b 122 Pfam PF00072 Response regulator receiver domain 3 115 1.4E-31 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS04245 a32e847bbab607c39626a0437bfa7f5b 122 SUPERFAMILY SSF52172 1 120 3.98E-37 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS04245 a32e847bbab607c39626a0437bfa7f5b 122 SMART SM00448 1 115 7.1E-35 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS04245 a32e847bbab607c39626a0437bfa7f5b 122 Gene3D G3DSA:3.40.50.2300 1 121 1.3E-38 T 05-07-2017 K08M4_RS14350 40cfefa4e30c619a16fbcdd036bdc718 212 Gene3D G3DSA:3.40.50.150 65 203 8.1E-12 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS14350 40cfefa4e30c619a16fbcdd036bdc718 212 Pfam PF13489 Methyltransferase domain 61 192 1.7E-17 T 05-07-2017 K08M4_RS14350 40cfefa4e30c619a16fbcdd036bdc718 212 SUPERFAMILY SSF53335 47 198 3.07E-19 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS03535 b2761d7a4f17e3cdf6055bfbb558cc2d 294 Gene3D G3DSA:1.10.600.10 4 292 2.8E-90 T 05-07-2017 IPR008949 Isoprenoid synthase domain K08M4_RS03535 b2761d7a4f17e3cdf6055bfbb558cc2d 294 Pfam PF00348 Polyprenyl synthetase 28 270 6.5E-57 T 05-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 K08M4_RS03535 b2761d7a4f17e3cdf6055bfbb558cc2d 294 SUPERFAMILY SSF48576 6 284 1.03E-83 T 05-07-2017 IPR008949 Isoprenoid synthase domain K08M4_RS03535 b2761d7a4f17e3cdf6055bfbb558cc2d 294 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 79 95 - T 05-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 K08M4_RS03535 b2761d7a4f17e3cdf6055bfbb558cc2d 294 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 213 225 - T 05-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 K08M4_RS03970 8c6e8f04c0ee2494bca4048bb84ba58e 256 SMART SM00563 86 196 1.5E-10 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 K08M4_RS03970 8c6e8f04c0ee2494bca4048bb84ba58e 256 SUPERFAMILY SSF69593 42 239 3.92E-22 T 05-07-2017 K08M4_RS03970 8c6e8f04c0ee2494bca4048bb84ba58e 256 Gene3D G3DSA:3.40.1130.10 75 249 2.8E-8 T 05-07-2017 K08M4_RS03970 8c6e8f04c0ee2494bca4048bb84ba58e 256 Pfam PF01553 Acyltransferase 73 189 1.8E-14 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 K08M4_RS07525 f61ce877c365d380c8066c7b2fe3850d 553 Pfam PF12838 4Fe-4S dicluster domain 185 231 1.7E-8 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain K08M4_RS07525 f61ce877c365d380c8066c7b2fe3850d 553 Gene3D G3DSA:3.30.70.20 417 454 1.4E-11 T 05-07-2017 K08M4_RS07525 f61ce877c365d380c8066c7b2fe3850d 553 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 420 431 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS07525 f61ce877c365d380c8066c7b2fe3850d 553 Gene3D G3DSA:3.30.70.20 170 235 5.7E-13 T 05-07-2017 K08M4_RS07525 f61ce877c365d380c8066c7b2fe3850d 553 SUPERFAMILY SSF54862 411 504 5.31E-40 T 05-07-2017 K08M4_RS07525 f61ce877c365d380c8066c7b2fe3850d 553 SUPERFAMILY SSF54862 141 238 5.31E-40 T 05-07-2017 K08M4_RS07525 f61ce877c365d380c8066c7b2fe3850d 553 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 451 462 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS07525 f61ce877c365d380c8066c7b2fe3850d 553 Pfam PF00037 4Fe-4S binding domain 419 435 1.5E-4 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain K08M4_RS07525 f61ce877c365d380c8066c7b2fe3850d 553 Pfam PF00037 4Fe-4S binding domain 446 467 3.9E-6 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain K08M4_RS07525 f61ce877c365d380c8066c7b2fe3850d 553 Gene3D G3DSA:3.30.70.20 455 497 1.1E-7 T 05-07-2017 K08M4_RS09630 89257b63cbe53839758a28d7b6fbba8e 530 Pfam PF03553 Na+/H+ antiporter family 165 495 2.2E-102 T 05-07-2017 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 K08M4_RS09505 89257b63cbe53839758a28d7b6fbba8e 530 Pfam PF03553 Na+/H+ antiporter family 165 495 2.2E-102 T 05-07-2017 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 K08M4_RS11735 8899a81a6933fbb52dcbcf0cfafcf3fb 161 TIGRFAM TIGR00086 smpB: SsrA-binding protein 15 157 6.9E-52 T 05-07-2017 IPR000037 SsrA-binding protein GO:0003723 K08M4_RS11735 8899a81a6933fbb52dcbcf0cfafcf3fb 161 Hamap MF_00023 SsrA-binding protein [smpB]. 1 161 68.371 T 05-07-2017 IPR000037 SsrA-binding protein GO:0003723 K08M4_RS11735 8899a81a6933fbb52dcbcf0cfafcf3fb 161 Gene3D G3DSA:2.40.280.10 14 134 1.9E-47 T 05-07-2017 IPR023620 Small protein B K08M4_RS11735 8899a81a6933fbb52dcbcf0cfafcf3fb 161 Pfam PF01668 SmpB protein 14 77 2.6E-28 T 05-07-2017 IPR000037 SsrA-binding protein GO:0003723 K08M4_RS11735 8899a81a6933fbb52dcbcf0cfafcf3fb 161 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 15 139 2.0E-54 T 05-07-2017 IPR000037 SsrA-binding protein GO:0003723 K08M4_RS11735 8899a81a6933fbb52dcbcf0cfafcf3fb 161 SUPERFAMILY SSF74982 8 139 7.85E-48 T 05-07-2017 IPR023620 Small protein B K08M4_RS11735 8899a81a6933fbb52dcbcf0cfafcf3fb 161 ProSitePatterns PS01317 SsrA-binding protein. 33 45 - T 05-07-2017 IPR020081 SsrA-binding protein, conserved site K08M4_RS13750 b4df3b34609c7f96461c0a655b76a432 314 Gene3D G3DSA:3.40.50.720 1 308 9.8E-58 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS13750 b4df3b34609c7f96461c0a655b76a432 314 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 219 1.4E-31 T 05-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 K08M4_RS13750 b4df3b34609c7f96461c0a655b76a432 314 SUPERFAMILY SSF51735 1 312 2.23E-65 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS01305 5d68ffb764be69327892b8f91a08f9d6 228 Gene3D G3DSA:1.10.150.240 26 89 1.8E-21 T 05-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 K08M4_RS01305 5d68ffb764be69327892b8f91a08f9d6 228 Gene3D G3DSA:3.40.50.1000 3 25 3.7E-44 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS01305 5d68ffb764be69327892b8f91a08f9d6 228 Gene3D G3DSA:3.40.50.1000 96 224 3.7E-44 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS01305 5d68ffb764be69327892b8f91a08f9d6 228 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 97 189 2.1E-10 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS01305 5d68ffb764be69327892b8f91a08f9d6 228 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 89 193 1.6E-15 T 05-07-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 K08M4_RS01305 5d68ffb764be69327892b8f91a08f9d6 228 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 81 194 6.4E-11 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS01305 5d68ffb764be69327892b8f91a08f9d6 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 157 177 2.2E-8 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS01305 5d68ffb764be69327892b8f91a08f9d6 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 2.2E-8 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS01305 5d68ffb764be69327892b8f91a08f9d6 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 2.2E-8 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS01305 5d68ffb764be69327892b8f91a08f9d6 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 139 155 2.2E-8 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS01305 5d68ffb764be69327892b8f91a08f9d6 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 193 1.8E-40 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS01305 5d68ffb764be69327892b8f91a08f9d6 228 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 6 225 34.006 T 05-07-2017 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 K08M4_RS01305 5d68ffb764be69327892b8f91a08f9d6 228 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 9 223 1.1E-57 T 05-07-2017 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 K08M4_RS01305 5d68ffb764be69327892b8f91a08f9d6 228 SUPERFAMILY SSF56784 5 224 5.51E-58 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS01650 a656e679a21b8b2bbaca4843189c31dc 377 Gene3D G3DSA:3.30.1490.20 112 166 8.0E-6 T 05-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 K08M4_RS01650 a656e679a21b8b2bbaca4843189c31dc 377 SUPERFAMILY SSF56059 240 317 1.37E-10 T 05-07-2017 K08M4_RS01650 a656e679a21b8b2bbaca4843189c31dc 377 SUPERFAMILY SSF56059 113 204 1.37E-10 T 05-07-2017 K08M4_RS19150 6f6001be9fc1ff64a737c3a01872bcec 6425 SUPERFAMILY SSF49464 4620 4689 3.88E-7 T 05-07-2017 IPR008969 Carboxypeptidase-like, regulatory domain K08M4_RS19150 6f6001be9fc1ff64a737c3a01872bcec 6425 Pfam PF13620 Carboxypeptidase regulatory-like domain 4621 4692 9.6E-8 T 05-07-2017 K08M4_RS19150 6f6001be9fc1ff64a737c3a01872bcec 6425 Gene3D G3DSA:2.60.40.1120 4621 4689 8.7E-7 T 05-07-2017 IPR014766 Carboxypeptidase, regulatory domain K08M4_RS07140 f8572fac1da2c9ec4e8b60ed88ca11b9 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 242 2.4E-57 T 05-07-2017 K08M4_RS07140 f8572fac1da2c9ec4e8b60ed88ca11b9 243 Gene3D G3DSA:3.40.50.720 3 243 1.7E-78 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS07140 f8572fac1da2c9ec4e8b60ed88ca11b9 243 SUPERFAMILY SSF51735 3 242 7.2E-76 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS07140 f8572fac1da2c9ec4e8b60ed88ca11b9 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.8E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS07140 f8572fac1da2c9ec4e8b60ed88ca11b9 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.8E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS07140 f8572fac1da2c9ec4e8b60ed88ca11b9 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.8E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS07140 f8572fac1da2c9ec4e8b60ed88ca11b9 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.8E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS07140 f8572fac1da2c9ec4e8b60ed88ca11b9 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.8E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS07140 f8572fac1da2c9ec4e8b60ed88ca11b9 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 2.8E-40 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS07140 f8572fac1da2c9ec4e8b60ed88ca11b9 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 05-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 K08M4_RS07140 f8572fac1da2c9ec4e8b60ed88ca11b9 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 174 5.9E-4 T 05-07-2017 K08M4_RS07140 f8572fac1da2c9ec4e8b60ed88ca11b9 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 5.5E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS07140 f8572fac1da2c9ec4e8b60ed88ca11b9 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 5.5E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS07140 f8572fac1da2c9ec4e8b60ed88ca11b9 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 5.5E-11 T 05-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR K08M4_RS16705 6ae433b0c5f4b6b88e7c7925502ad84b 210 SUPERFAMILY SSF56529 18 194 3.4E-46 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 K08M4_RS16705 6ae433b0c5f4b6b88e7c7925502ad84b 210 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 21 185 3.0E-28 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 K08M4_RS16705 6ae433b0c5f4b6b88e7c7925502ad84b 210 Gene3D G3DSA:3.90.850.10 15 195 7.1E-47 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 K08M4_RS07845 d487781c3e84ce567529af4a481bb2e0 598 Gene3D G3DSA:1.20.1560.10 12 341 1.5E-52 T 05-07-2017 K08M4_RS07845 d487781c3e84ce567529af4a481bb2e0 598 Pfam PF00005 ABC transporter 376 524 1.7E-32 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS07845 d487781c3e84ce567529af4a481bb2e0 598 SUPERFAMILY SSF52540 356 592 4.39E-80 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07845 d487781c3e84ce567529af4a481bb2e0 598 Pfam PF00664 ABC transporter transmembrane region 29 313 8.5E-29 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS07845 d487781c3e84ce567529af4a481bb2e0 598 SMART SM00382 385 576 1.6E-13 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS07845 d487781c3e84ce567529af4a481bb2e0 598 Gene3D G3DSA:3.40.50.300 361 594 9.4E-73 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07845 d487781c3e84ce567529af4a481bb2e0 598 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS07845 d487781c3e84ce567529af4a481bb2e0 598 SUPERFAMILY SSF90123 12 345 7.59E-55 T 05-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 K08M4_RS05680 aae7562aeabae7060f0b5239eab30f03 339 Pfam PF00535 Glycosyl transferase family 2 23 185 9.1E-30 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 K08M4_RS05680 aae7562aeabae7060f0b5239eab30f03 339 ProSitePatterns PS00221 MIP family signature. 15 23 - T 05-07-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 K08M4_RS05680 aae7562aeabae7060f0b5239eab30f03 339 SUPERFAMILY SSF53448 19 195 6.88E-36 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS05680 aae7562aeabae7060f0b5239eab30f03 339 Gene3D G3DSA:3.90.550.10 22 182 2.5E-23 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS19790 927eba90db49186ef10d3d8ee005ba35 259 SUPERFAMILY SSF52540 8 220 7.1E-50 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19790 927eba90db49186ef10d3d8ee005ba35 259 Gene3D G3DSA:3.40.50.300 8 219 7.3E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19790 927eba90db49186ef10d3d8ee005ba35 259 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS19790 927eba90db49186ef10d3d8ee005ba35 259 Pfam PF00005 ABC transporter 25 174 2.6E-26 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS19790 927eba90db49186ef10d3d8ee005ba35 259 SMART SM00382 34 221 1.2E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS03150 126dee5204e214f7f5e9fd2a9c2cd487 307 SUPERFAMILY SSF48452 33 282 8.18E-65 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS03150 126dee5204e214f7f5e9fd2a9c2cd487 307 Gene3D G3DSA:1.25.40.10 48 266 4.3E-23 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS03150 126dee5204e214f7f5e9fd2a9c2cd487 307 PIRSF PIRSF004654 1 293 1.2E-86 T 05-07-2017 IPR023605 Lipoprotein NlpI K08M4_RS03150 126dee5204e214f7f5e9fd2a9c2cd487 307 SMART SM00028 65 98 0.35 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS03150 126dee5204e214f7f5e9fd2a9c2cd487 307 SMART SM00028 236 269 63.0 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS03150 126dee5204e214f7f5e9fd2a9c2cd487 307 SMART SM00028 99 132 0.015 T 05-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 K08M4_RS20730 6e324643e93cd18ab4ffddc68f296d58 204 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 174 1.1E-24 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS20730 6e324643e93cd18ab4ffddc68f296d58 204 SUPERFAMILY SSF88946 21 107 1.02E-19 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS20730 6e324643e93cd18ab4ffddc68f296d58 204 Gene3D G3DSA:1.10.10.10 118 180 1.4E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20730 6e324643e93cd18ab4ffddc68f296d58 204 Pfam PF04542 Sigma-70 region 2 26 91 9.1E-15 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS20730 6e324643e93cd18ab4ffddc68f296d58 204 Gene3D G3DSA:1.10.1740.10 21 113 6.4E-21 T 05-07-2017 K08M4_RS20730 6e324643e93cd18ab4ffddc68f296d58 204 TIGRFAM TIGR02959 SigZ: RNA polymerase sigma factor, SigZ family 25 195 4.8E-55 T 05-07-2017 IPR014304 RNA polymerase sigma-Z type K08M4_RS20730 6e324643e93cd18ab4ffddc68f296d58 204 SUPERFAMILY SSF88659 118 178 2.8E-10 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS20730 6e324643e93cd18ab4ffddc68f296d58 204 Pfam PF08281 Sigma-70, region 4 123 170 2.0E-10 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS01410 bc62791d062a06a8b5676c26f554f748 325 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 176 190 - T 05-07-2017 IPR019775 WD40 repeat, conserved site K08M4_RS01410 bc62791d062a06a8b5676c26f554f748 325 Gene3D G3DSA:2.130.10.10 94 324 3.0E-38 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 K08M4_RS01410 bc62791d062a06a8b5676c26f554f748 325 Pfam PF00400 WD domain, G-beta repeat 157 189 0.0063 T 05-07-2017 IPR001680 WD40 repeat GO:0005515 K08M4_RS01410 bc62791d062a06a8b5676c26f554f748 325 SMART SM00320 192 230 0.16 T 05-07-2017 IPR001680 WD40 repeat GO:0005515 K08M4_RS01410 bc62791d062a06a8b5676c26f554f748 325 SMART SM00320 233 274 0.39 T 05-07-2017 IPR001680 WD40 repeat GO:0005515 K08M4_RS01410 bc62791d062a06a8b5676c26f554f748 325 SMART SM00320 285 323 22.0 T 05-07-2017 IPR001680 WD40 repeat GO:0005515 K08M4_RS01410 bc62791d062a06a8b5676c26f554f748 325 SMART SM00320 65 106 32.0 T 05-07-2017 IPR001680 WD40 repeat GO:0005515 K08M4_RS01410 bc62791d062a06a8b5676c26f554f748 325 SMART SM00320 151 189 1.9E-4 T 05-07-2017 IPR001680 WD40 repeat GO:0005515 K08M4_RS01410 bc62791d062a06a8b5676c26f554f748 325 SUPERFAMILY SSF50998 28 324 5.89E-43 T 05-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily K08M4_RS01410 bc62791d062a06a8b5676c26f554f748 325 Gene3D G3DSA:2.130.10.10 34 93 8.1E-7 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 K08M4_RS01125 5bbef29cdb6eb8531683788aef089ddb 305 PIRSF PIRSF005355 1 303 1.2E-83 T 05-07-2017 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 K08M4_RS01125 5bbef29cdb6eb8531683788aef089ddb 305 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 13 296 1.8E-97 T 05-07-2017 K08M4_RS01125 5bbef29cdb6eb8531683788aef089ddb 305 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 4 298 20.819 T 05-07-2017 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 K08M4_RS01125 5bbef29cdb6eb8531683788aef089ddb 305 Pfam PF01040 UbiA prenyltransferase family 21 272 1.1E-39 T 05-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 K08M4_RS01580 ac0d3c33839f80020ccb96d07be1e8b0 129 Pfam PF00411 Ribosomal protein S11 19 128 1.0E-51 T 05-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 K08M4_RS01580 ac0d3c33839f80020ccb96d07be1e8b0 129 PIRSF PIRSF002131 1 129 3.3E-52 T 05-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 K08M4_RS01580 ac0d3c33839f80020ccb96d07be1e8b0 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 1.7E-54 T 05-07-2017 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 K08M4_RS01580 ac0d3c33839f80020ccb96d07be1e8b0 129 SUPERFAMILY SSF53137 14 129 1.77E-47 T 05-07-2017 K08M4_RS01580 ac0d3c33839f80020ccb96d07be1e8b0 129 Gene3D G3DSA:3.30.420.80 7 129 3.5E-53 T 05-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 K08M4_RS01580 ac0d3c33839f80020ccb96d07be1e8b0 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 32.445 T 05-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 K08M4_RS01580 ac0d3c33839f80020ccb96d07be1e8b0 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 05-07-2017 IPR018102 Ribosomal S11, conserved site K08M4_RS10965 5fc8d3a9d34e94999ffe0e8d91d0c391 343 Gene3D G3DSA:3.40.630.10 28 226 2.1E-25 T 05-07-2017 K08M4_RS10965 5fc8d3a9d34e94999ffe0e8d91d0c391 343 SUPERFAMILY SSF53187 17 315 5.29E-69 T 05-07-2017 K08M4_RS10965 5fc8d3a9d34e94999ffe0e8d91d0c391 343 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 44 314 5.8E-57 T 05-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 K08M4_RS10965 5fc8d3a9d34e94999ffe0e8d91d0c391 343 PIRSF PIRSF039012 4 322 1.0E-82 T 05-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 K08M4_RS12940 801399d42fb884ca8fc894e72da53a92 260 Pfam PF04784 Protein of unknown function, DUF547 89 198 1.3E-23 T 05-07-2017 IPR006869 Domain of unknown function DUF547 K08M4_RS07635 58d25c5df24583d226d9cc37f361f149 78 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 45 4.1E-21 T 05-07-2017 IPR004714 Cytochrome oxidase maturation protein cbb3-type K08M4_RS07635 58d25c5df24583d226d9cc37f361f149 78 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 47 6.6E-16 T 05-07-2017 IPR004714 Cytochrome oxidase maturation protein cbb3-type K08M4_RS18795 e9dad5769eb91f5398bff6dc74e5bdba 246 Pfam PF06764 Protein of unknown function (DUF1223) 41 229 4.2E-49 T 05-07-2017 IPR010634 Protein of unknown function DUF1223 K08M4_RS18795 e9dad5769eb91f5398bff6dc74e5bdba 246 SUPERFAMILY SSF52833 35 244 9.94E-56 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS15665 ccb2aa5e6fde834258e7037ea1673fdf 155 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 146 8.4E-29 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS15665 ccb2aa5e6fde834258e7037ea1673fdf 155 Gene3D G3DSA:3.40.930.10 6 147 3.5E-45 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS15665 ccb2aa5e6fde834258e7037ea1673fdf 155 SUPERFAMILY SSF55804 5 146 1.7E-31 T 05-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 K08M4_RS13850 cc19f21c61d5d169612eb332eddb5eaa 649 SUPERFAMILY SSF56784 12 231 6.03E-17 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS13850 cc19f21c61d5d169612eb332eddb5eaa 649 Gene3D G3DSA:3.40.50.1000 11 28 1.7E-14 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS13850 cc19f21c61d5d169612eb332eddb5eaa 649 Gene3D G3DSA:3.40.50.1000 120 226 1.7E-14 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS13850 cc19f21c61d5d169612eb332eddb5eaa 649 Pfam PF13419 Haloacid dehalogenase-like hydrolase 109 219 1.6E-6 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS06795 5606f0f5f27d81ceba5746763aa60734 284 PIRSF PIRSF015558 1 282 3.4E-73 T 05-07-2017 IPR016634 WYL domain protein, s026 type K08M4_RS06795 5606f0f5f27d81ceba5746763aa60734 284 Pfam PF13280 WYL domain 126 208 3.6E-9 T 05-07-2017 IPR026881 WYL domain K08M4_RS09330 ebe288c7e0213266f1751e0c826c4e59 77 TIGRFAM TIGR02976 phageshock_pspB: phage shock protein B 1 74 9.0E-33 T 05-07-2017 IPR009554 Phage shock protein B GO:0006355|GO:0009271 K08M4_RS09330 ebe288c7e0213266f1751e0c826c4e59 77 Pfam PF06667 Phage shock protein B 4 74 9.1E-34 T 05-07-2017 IPR009554 Phage shock protein B GO:0006355|GO:0009271 K08M4_RS04000 93661711c67156de493b0e18790c502a 377 Pfam PF16538 Flagellar assembly protein T, C-terminal domain 299 374 6.6E-27 T 05-07-2017 IPR032388 Flagellar assembly protein T, C-terminal K08M4_RS04000 93661711c67156de493b0e18790c502a 377 Pfam PF16539 Flagellar assembly protein T, middle domain 114 256 3.5E-41 T 05-07-2017 IPR032386 Flagellar assembly protein T, middle domain K08M4_RS04000 93661711c67156de493b0e18790c502a 377 Pfam PF16548 Flagellar assembly protein T, N-terminal domain 24 110 1.5E-24 T 05-07-2017 IPR032370 Flagellar assembly protein T, N-terminal K08M4_RS01950 2a72fe97725c9bcba62f73548b27daf1 356 Pfam PF03739 Predicted permease YjgP/YjgQ family 8 354 1.8E-65 T 05-07-2017 IPR005495 Permease LptG/LptF-related GO:0016021 K08M4_RS01950 2a72fe97725c9bcba62f73548b27daf1 356 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 354 6.4E-131 T 05-07-2017 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 K08M4_RS15915 96c39044f835bbbdafea2925ff7804e2 300 SUPERFAMILY SSF103481 220 298 5.49E-9 T 05-07-2017 K08M4_RS15915 96c39044f835bbbdafea2925ff7804e2 300 Pfam PF00892 EamA-like transporter family 3 137 2.8E-14 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS15915 96c39044f835bbbdafea2925ff7804e2 300 Pfam PF00892 EamA-like transporter family 155 298 2.0E-13 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS15915 96c39044f835bbbdafea2925ff7804e2 300 SUPERFAMILY SSF103481 44 141 4.84E-9 T 05-07-2017 K08M4_RS12780 6407602569b722c9812c735537c56d36 552 SUPERFAMILY SSF47090 467 539 1.15E-11 T 05-07-2017 IPR002477 Peptidoglycan binding-like K08M4_RS12780 6407602569b722c9812c735537c56d36 552 Gene3D G3DSA:1.10.101.10 469 536 1.4E-11 T 05-07-2017 IPR002477 Peptidoglycan binding-like K08M4_RS12780 6407602569b722c9812c735537c56d36 552 Pfam PF01471 Putative peptidoglycan binding domain 478 533 1.6E-6 T 05-07-2017 IPR002477 Peptidoglycan binding-like K08M4_RS12780 6407602569b722c9812c735537c56d36 552 SUPERFAMILY SSF52540 2 254 7.51E-34 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12780 6407602569b722c9812c735537c56d36 552 Gene3D G3DSA:3.40.50.300 17 173 5.0E-22 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS12780 6407602569b722c9812c735537c56d36 552 SMART SM00382 32 185 5.6E-6 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS12780 6407602569b722c9812c735537c56d36 552 Pfam PF13401 AAA domain 32 159 4.6E-24 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS10410 ee5e4529734e2b5221e4b441de1590ef 453 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 437 1.9E-116 T 05-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit K08M4_RS10410 ee5e4529734e2b5221e4b441de1590ef 453 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 260 3.9E-84 T 05-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 K08M4_RS16335 a1ef1a096279d417419ea22ae6649705 260 Pfam PF00005 ABC transporter 21 170 9.9E-25 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS16335 a1ef1a096279d417419ea22ae6649705 260 SUPERFAMILY SSF52540 5 234 7.93E-51 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16335 a1ef1a096279d417419ea22ae6649705 260 SMART SM00382 30 219 5.8E-14 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS16335 a1ef1a096279d417419ea22ae6649705 260 Gene3D G3DSA:3.40.50.300 7 240 4.6E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04415 d435797d1711d086729d0bbea400256b 285 SUPERFAMILY SSF161098 8 285 2.99E-65 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS04415 d435797d1711d086729d0bbea400256b 285 Gene3D G3DSA:1.10.3720.10 6 270 4.8E-55 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS04415 d435797d1711d086729d0bbea400256b 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 278 2.8E-17 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS05000 b93b381488cfc0507f0bfabb4714da52 321 Pfam PF04392 ABC transporter substrate binding protein 29 317 5.5E-99 T 05-07-2017 IPR007487 ABC transporter, substrate-binding protein K08M4_RS05000 b93b381488cfc0507f0bfabb4714da52 321 Gene3D G3DSA:3.40.50.2300 156 287 4.1E-41 T 05-07-2017 K08M4_RS05000 b93b381488cfc0507f0bfabb4714da52 321 SUPERFAMILY SSF53822 57 276 2.08E-11 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS05000 b93b381488cfc0507f0bfabb4714da52 321 Gene3D G3DSA:3.40.50.2300 29 155 4.3E-48 T 05-07-2017 K08M4_RS19495 a11fbee25570aa7718d00444b7a7cd9a 285 SUPERFAMILY SSF117892 54 188 5.49E-13 T 05-07-2017 IPR001107 Band 7 domain K08M4_RS19495 a11fbee25570aa7718d00444b7a7cd9a 285 SMART SM00244 23 185 3.1E-14 T 05-07-2017 IPR001107 Band 7 domain K08M4_RS19495 a11fbee25570aa7718d00444b7a7cd9a 285 Pfam PF01145 SPFH domain / Band 7 family 27 206 5.2E-25 T 05-07-2017 IPR001107 Band 7 domain K08M4_RS15805 8d133c20cc7daa2ffb057e7d59dc5707 588 SUPERFAMILY SSF51445 4 484 1.25E-80 T 05-07-2017 IPR017853 Glycoside hydrolase superfamily K08M4_RS15805 8d133c20cc7daa2ffb057e7d59dc5707 588 SMART SM00642 10 457 1.4E-7 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS15805 8d133c20cc7daa2ffb057e7d59dc5707 588 Gene3D G3DSA:3.20.20.80 4 480 1.6E-81 T 05-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 K08M4_RS15805 8d133c20cc7daa2ffb057e7d59dc5707 588 Pfam PF00128 Alpha amylase, catalytic domain 272 428 5.1E-14 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS15805 8d133c20cc7daa2ffb057e7d59dc5707 588 Pfam PF00128 Alpha amylase, catalytic domain 48 144 3.2E-9 T 05-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 K08M4_RS07585 1ddd39e216bebf80a77e28c9d9781215 256 Gene3D G3DSA:1.10.3720.10 3 254 2.8E-57 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07585 1ddd39e216bebf80a77e28c9d9781215 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 250 1.3E-18 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07585 1ddd39e216bebf80a77e28c9d9781215 256 SUPERFAMILY SSF161098 5 254 6.73E-55 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS04570 34b2a85e32dc7692087237b38befee37 191 SUPERFAMILY SSF110997 114 187 4.58E-15 T 05-07-2017 IPR007730 Sporulation-related domain GO:0042834 K08M4_RS04570 34b2a85e32dc7692087237b38befee37 191 Gene3D G3DSA:3.30.70.1070 109 188 7.7E-21 T 05-07-2017 IPR007730 Sporulation-related domain GO:0042834 K08M4_RS04570 34b2a85e32dc7692087237b38befee37 191 Pfam PF05036 Sporulation related domain 115 183 2.1E-12 T 05-07-2017 IPR007730 Sporulation-related domain GO:0042834 K08M4_RS12135 f661202c639bed64e32a7ebb66b4af4a 117 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 92 6.9E-21 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 K08M4_RS12135 f661202c639bed64e32a7ebb66b4af4a 117 SUPERFAMILY SSF69754 2 109 1.7E-28 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 K08M4_RS12135 f661202c639bed64e32a7ebb66b4af4a 117 Gene3D G3DSA:3.30.160.100 2 92 2.4E-28 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 K08M4_RS12135 f661202c639bed64e32a7ebb66b4af4a 117 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 99 4.6E-29 T 05-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 K08M4_RS06520 31d9e02e006ed360b7855652b9af3160 347 Gene3D G3DSA:1.10.10.60 293 341 2.0E-14 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS06520 31d9e02e006ed360b7855652b9af3160 347 Gene3D G3DSA:1.10.10.10 246 280 0.001 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS06520 31d9e02e006ed360b7855652b9af3160 347 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 32 214 1.2E-30 T 05-07-2017 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal K08M4_RS06520 31d9e02e006ed360b7855652b9af3160 347 SMART SM00342 258 340 1.0E-20 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS06520 31d9e02e006ed360b7855652b9af3160 347 Pfam PF12833 Helix-turn-helix domain 264 341 8.5E-18 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS06520 31d9e02e006ed360b7855652b9af3160 347 SUPERFAMILY SSF46689 293 342 6.27E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS10020 05a7515b56f0c53b39043d83dd937701 255 SUPERFAMILY SSF52540 4 231 3.45E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10020 05a7515b56f0c53b39043d83dd937701 255 Gene3D G3DSA:3.40.50.300 4 230 9.0E-65 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10020 05a7515b56f0c53b39043d83dd937701 255 Pfam PF00005 ABC transporter 19 166 3.2E-31 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS10020 05a7515b56f0c53b39043d83dd937701 255 SMART SM00382 26 214 6.3E-12 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS10020 05a7515b56f0c53b39043d83dd937701 255 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS03600 71f3ada5c7a6926b443b7cdc8bdf894e 392 Gene3D G3DSA:3.40.710.10 31 282 7.5E-98 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS03600 71f3ada5c7a6926b443b7cdc8bdf894e 392 SUPERFAMILY SSF69189 283 375 1.41E-27 T 05-07-2017 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 K08M4_RS03600 71f3ada5c7a6926b443b7cdc8bdf894e 392 SUPERFAMILY SSF56601 12 283 3.53E-85 T 05-07-2017 IPR012338 Beta-lactamase/transpeptidase-like K08M4_RS03600 71f3ada5c7a6926b443b7cdc8bdf894e 392 SMART SM00936 283 373 1.1E-37 T 05-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 K08M4_RS03600 71f3ada5c7a6926b443b7cdc8bdf894e 392 Gene3D G3DSA:2.60.410.10 283 373 1.5E-31 T 05-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 K08M4_RS03600 71f3ada5c7a6926b443b7cdc8bdf894e 392 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 122 139 3.5E-17 T 05-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 K08M4_RS03600 71f3ada5c7a6926b443b7cdc8bdf894e 392 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 149 162 3.5E-17 T 05-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 K08M4_RS03600 71f3ada5c7a6926b443b7cdc8bdf894e 392 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 66 77 3.5E-17 T 05-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 K08M4_RS03600 71f3ada5c7a6926b443b7cdc8bdf894e 392 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 283 372 9.2E-27 T 05-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 K08M4_RS03600 71f3ada5c7a6926b443b7cdc8bdf894e 392 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 34 263 8.3E-93 T 05-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 K08M4_RS17790 3b03e61623b8bc7f5acdf14233d22368 309 SUPERFAMILY SSF103481 39 138 1.7E-10 T 05-07-2017 K08M4_RS17790 3b03e61623b8bc7f5acdf14233d22368 309 Pfam PF00892 EamA-like transporter family 3 136 8.8E-10 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS17790 3b03e61623b8bc7f5acdf14233d22368 309 Pfam PF00892 EamA-like transporter family 149 288 4.4E-10 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS17790 3b03e61623b8bc7f5acdf14233d22368 309 SUPERFAMILY SSF103481 203 288 9.94E-9 T 05-07-2017 K08M4_RS19890 3333643922268f84f33e5899c9a15d34 223 Pfam PF09669 Phage regulatory protein Rha (Phage_pRha) 23 107 6.2E-28 T 05-07-2017 IPR014054 Bacteriophage regulatory protein, Rha family K08M4_RS19890 3333643922268f84f33e5899c9a15d34 223 TIGRFAM TIGR02681 phage_pRha: phage regulatory protein, Rha family 12 111 1.5E-26 T 05-07-2017 IPR014054 Bacteriophage regulatory protein, Rha family K08M4_RS18345 15e4264545d8a024bd54a260f7f8513b 383 Gene3D G3DSA:1.20.1250.20 205 377 2.6E-12 T 05-07-2017 K08M4_RS18345 15e4264545d8a024bd54a260f7f8513b 383 Gene3D G3DSA:1.20.1250.20 12 178 1.8E-16 T 05-07-2017 K08M4_RS18345 15e4264545d8a024bd54a260f7f8513b 383 Pfam PF07690 Major Facilitator Superfamily 15 340 3.4E-23 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS18345 15e4264545d8a024bd54a260f7f8513b 383 SUPERFAMILY SSF103473 15 372 1.83E-33 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS09105 d1bfb63c545ab712e70dff44759f75f0 377 SUPERFAMILY SSF47240 3 341 6.67E-112 T 05-07-2017 IPR009078 Ferritin-like superfamily K08M4_RS09105 d1bfb63c545ab712e70dff44759f75f0 377 Pfam PF00268 Ribonucleotide reductase, small chain 34 333 2.1E-48 T 05-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS09105 d1bfb63c545ab712e70dff44759f75f0 377 Gene3D G3DSA:1.10.620.20 3 341 1.1E-123 T 05-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 K08M4_RS09105 d1bfb63c545ab712e70dff44759f75f0 377 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 115 131 - T 05-07-2017 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 K08M4_RS11960 cb404449204560324fb991a01747111c 456 Gene3D G3DSA:3.30.1360.60 1 82 3.5E-23 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS11960 cb404449204560324fb991a01747111c 456 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS11960 cb404449204560324fb991a01747111c 456 Pfam PF02378 Phosphotransferase system, EIIC 110 393 5.2E-35 T 05-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 K08M4_RS11960 cb404449204560324fb991a01747111c 456 Pfam PF00367 phosphotransferase system, EIIB 9 41 5.5E-15 T 05-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 K08M4_RS11960 cb404449204560324fb991a01747111c 456 SUPERFAMILY SSF55604 7 80 1.44E-18 T 05-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 K08M4_RS06045 aa3c45837aad05de95eb1f7c72959ac0 564 Pfam PF01175 Urocanase 17 549 2.0E-259 T 05-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 K08M4_RS06045 aa3c45837aad05de95eb1f7c72959ac0 564 ProSitePatterns PS01233 Urocanase signature. 444 459 - T 05-07-2017 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 K08M4_RS06045 aa3c45837aad05de95eb1f7c72959ac0 564 SUPERFAMILY SSF111326 11 557 2.62E-258 T 05-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 K08M4_RS06045 aa3c45837aad05de95eb1f7c72959ac0 564 Gene3D G3DSA:3.40.1770.10 362 557 3.1E-163 T 05-07-2017 K08M4_RS06045 aa3c45837aad05de95eb1f7c72959ac0 564 Gene3D G3DSA:3.40.1770.10 14 146 3.1E-163 T 05-07-2017 K08M4_RS06045 aa3c45837aad05de95eb1f7c72959ac0 564 Gene3D G3DSA:3.40.50.10730 147 351 4.4E-90 T 05-07-2017 K08M4_RS06045 aa3c45837aad05de95eb1f7c72959ac0 564 Hamap MF_00577 Urocanate hydratase [hutU]. 4 558 49.257 T 05-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 K08M4_RS06045 aa3c45837aad05de95eb1f7c72959ac0 564 PIRSF PIRSF001423 1 563 1.9E-294 T 05-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 K08M4_RS06045 aa3c45837aad05de95eb1f7c72959ac0 564 TIGRFAM TIGR01228 hutU: urocanate hydratase 15 556 1.0E-291 T 05-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 K08M4_RS01140 460da58655fdd0e61658aacb6321faf0 179 Pfam PF05036 Sporulation related domain 105 174 1.9E-13 T 05-07-2017 IPR007730 Sporulation-related domain GO:0042834 K08M4_RS01140 460da58655fdd0e61658aacb6321faf0 179 Gene3D G3DSA:3.30.70.1070 99 175 2.3E-25 T 05-07-2017 IPR007730 Sporulation-related domain GO:0042834 K08M4_RS01140 460da58655fdd0e61658aacb6321faf0 179 SUPERFAMILY SSF110997 104 175 4.58E-16 T 05-07-2017 IPR007730 Sporulation-related domain GO:0042834 K08M4_RS09430 76e614badbd70f408a56ca913c50613a 226 Pfam PF02698 DUF218 domain 36 164 3.6E-23 T 05-07-2017 IPR003848 Domain of unknown function DUF218 K08M4_RS09430 76e614badbd70f408a56ca913c50613a 226 Gene3D G3DSA:3.40.50.620 27 166 1.5E-50 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS14245 514b76da309d61c6bbb0dcf66fd0036f 674 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 30 621 1.2E-158 T 05-07-2017 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 K08M4_RS14245 514b76da309d61c6bbb0dcf66fd0036f 674 PRINTS PR00811 Bacterial general secretion pathway protein D signature 599 613 7.7E-37 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS14245 514b76da309d61c6bbb0dcf66fd0036f 674 PRINTS PR00811 Bacterial general secretion pathway protein D signature 481 491 7.7E-37 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS14245 514b76da309d61c6bbb0dcf66fd0036f 674 PRINTS PR00811 Bacterial general secretion pathway protein D signature 344 354 7.7E-37 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS14245 514b76da309d61c6bbb0dcf66fd0036f 674 PRINTS PR00811 Bacterial general secretion pathway protein D signature 446 470 7.7E-37 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS14245 514b76da309d61c6bbb0dcf66fd0036f 674 PRINTS PR00811 Bacterial general secretion pathway protein D signature 576 594 7.7E-37 T 05-07-2017 IPR001775 GspD/PilQ family K08M4_RS14245 514b76da309d61c6bbb0dcf66fd0036f 674 PRINTS PR01032 Gene IV protein signature 471 494 3.1E-12 T 05-07-2017 K08M4_RS14245 514b76da309d61c6bbb0dcf66fd0036f 674 PRINTS PR01032 Gene IV protein signature 592 614 3.1E-12 T 05-07-2017 K08M4_RS14245 514b76da309d61c6bbb0dcf66fd0036f 674 PRINTS PR01032 Gene IV protein signature 539 567 3.1E-12 T 05-07-2017 K08M4_RS14245 514b76da309d61c6bbb0dcf66fd0036f 674 Pfam PF00263 Bacterial type II and III secretion system protein 450 612 3.4E-51 T 05-07-2017 IPR004846 Type II/III secretion system GO:0009306 K08M4_RS14245 514b76da309d61c6bbb0dcf66fd0036f 674 Pfam PF03958 Bacterial type II/III secretion system short domain 192 259 3.5E-15 T 05-07-2017 IPR005644 NolW-like K08M4_RS14245 514b76da309d61c6bbb0dcf66fd0036f 674 Pfam PF03958 Bacterial type II/III secretion system short domain 267 344 1.1E-18 T 05-07-2017 IPR005644 NolW-like K08M4_RS14245 514b76da309d61c6bbb0dcf66fd0036f 674 Pfam PF03958 Bacterial type II/III secretion system short domain 126 187 5.1E-9 T 05-07-2017 IPR005644 NolW-like K08M4_RS14245 514b76da309d61c6bbb0dcf66fd0036f 674 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 557 590 - T 05-07-2017 IPR004845 Type II secretion system GspD, conserved site GO:0008565 K08M4_RS14755 d4e1b523d60a61a69bce4b51c8b6ff0a 185 SUPERFAMILY SSF55821 2 182 6.71E-57 T 05-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain K08M4_RS14755 d4e1b523d60a61a69bce4b51c8b6ff0a 185 Gene3D G3DSA:3.90.870.10 3 185 2.6E-58 T 05-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain K08M4_RS14755 d4e1b523d60a61a69bce4b51c8b6ff0a 185 Pfam PF01300 Telomere recombination 9 185 3.9E-50 T 05-07-2017 IPR006070 YrdC-like domain GO:0003725 K08M4_RS14755 d4e1b523d60a61a69bce4b51c8b6ff0a 185 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 5 185 1.0E-38 T 05-07-2017 IPR006070 YrdC-like domain GO:0003725 K08M4_RS14755 d4e1b523d60a61a69bce4b51c8b6ff0a 185 Hamap MF_01852 Threonylcarbamoyl-AMP synthase [tsaC]. 1 183 40.705 T 05-07-2017 IPR023535 Threonylcarbamoyl-AMP synthase GO:0002949|GO:0005524 K08M4_RS02165 7069bad7c676d9edd97c7a1c3f3a889e 369 Gene3D G3DSA:3.40.50.300 100 342 1.0E-62 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02165 7069bad7c676d9edd97c7a1c3f3a889e 369 SUPERFAMILY SSF52540 3 333 1.25E-69 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02165 7069bad7c676d9edd97c7a1c3f3a889e 369 Pfam PF00437 Type II/IV secretion system protein 12 269 3.4E-38 T 05-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 K08M4_RS02165 7069bad7c676d9edd97c7a1c3f3a889e 369 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 341 5.8E-127 T 05-07-2017 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 K08M4_RS14775 7ccfd3027427e36b49994ce41cd539e7 158 Pfam PF04361 Protein of unknown function (DUF494) 2 158 1.4E-58 T 05-07-2017 IPR007456 Smg K08M4_RS14775 7ccfd3027427e36b49994ce41cd539e7 158 Hamap MF_00598 Protein Smg [smg]. 2 158 32.3 T 05-07-2017 IPR007456 Smg K08M4_RS16210 8133f0d82efaba68070a8e78623011e5 395 ProDom PD037532 SYNTHASE LACTONE HOMOSERINE AUTOINDUCER N-OCTANOYL VANM AINS LUXM SYNTHESIS 184 388 3.0E-75 T 05-07-2017 IPR020384 Homoserine lactone synthase, LuxM/VanM, C-terminal GO:0016747 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 K08M4_RS16210 8133f0d82efaba68070a8e78623011e5 395 ProDom PD097636 LACTONE SYNTHASE HOMOSERINE VANM AUTOINDUCER SYNTHESIS LUXL 16 159 2.0E-48 T 05-07-2017 IPR020374 Homoserine lactone synthase, LuxM/VanM, N-terminal GO:0016747 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 K08M4_RS18540 37fe93c324100b2b0a8d6fa008f669d4 651 Pfam PF13175 AAA ATPase domain 1 392 6.7E-49 T 05-07-2017 K08M4_RS18540 37fe93c324100b2b0a8d6fa008f669d4 651 SUPERFAMILY SSF52540 223 393 2.59E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18540 37fe93c324100b2b0a8d6fa008f669d4 651 SUPERFAMILY SSF52540 1 156 2.59E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18540 37fe93c324100b2b0a8d6fa008f669d4 651 Gene3D G3DSA:3.40.50.300 257 422 6.6E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18540 37fe93c324100b2b0a8d6fa008f669d4 651 Gene3D G3DSA:3.40.50.300 132 206 6.6E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18540 37fe93c324100b2b0a8d6fa008f669d4 651 Gene3D G3DSA:3.40.50.300 1 89 6.6E-29 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18420 e5bdeb5ff2d236d77232d5a20bff32f8 394 SUPERFAMILY SSF53383 1 392 1.68E-99 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS18420 e5bdeb5ff2d236d77232d5a20bff32f8 394 PRINTS PR00799 Aspartate aminotransferase signature 172 191 8.6E-29 T 05-07-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 K08M4_RS18420 e5bdeb5ff2d236d77232d5a20bff32f8 394 PRINTS PR00799 Aspartate aminotransferase signature 270 295 8.6E-29 T 05-07-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 K08M4_RS18420 e5bdeb5ff2d236d77232d5a20bff32f8 394 PRINTS PR00799 Aspartate aminotransferase signature 203 215 8.6E-29 T 05-07-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 K08M4_RS18420 e5bdeb5ff2d236d77232d5a20bff32f8 394 PRINTS PR00799 Aspartate aminotransferase signature 338 356 8.6E-29 T 05-07-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 K08M4_RS18420 e5bdeb5ff2d236d77232d5a20bff32f8 394 Pfam PF00155 Aminotransferase class I and II 26 389 7.4E-68 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS18420 e5bdeb5ff2d236d77232d5a20bff32f8 394 Gene3D G3DSA:3.40.640.10 46 311 3.2E-87 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS11760 0c771c4e886685ac5fa59c9d301e7156 264 Pfam PF04143 Sulphur transport 129 256 2.0E-14 T 05-07-2017 IPR007272 Sulphur transport domain K08M4_RS11760 0c771c4e886685ac5fa59c9d301e7156 264 Pfam PF04143 Sulphur transport 11 92 4.9E-7 T 05-07-2017 IPR007272 Sulphur transport domain K08M4_RS19870 c63680af60a15b9c14de7a4597b52a3e 123 Pfam PF14534 Domain of unknown function (DUF4440) 5 109 4.4E-6 T 05-07-2017 IPR027843 Domain of unknown function DUF4440 K08M4_RS19870 c63680af60a15b9c14de7a4597b52a3e 123 SUPERFAMILY SSF54427 3 116 2.89E-9 T 05-07-2017 IPR032710 NTF2-like domain K08M4_RS19870 c63680af60a15b9c14de7a4597b52a3e 123 Gene3D G3DSA:3.10.450.50 4 116 1.2E-6 T 05-07-2017 IPR032710 NTF2-like domain K08M4_RS08420 94a9745b948c6f3034b0b434591c6ae8 646 SUPERFAMILY SSF53067 226 376 4.05E-25 T 05-07-2017 K08M4_RS08420 94a9745b948c6f3034b0b434591c6ae8 646 SUPERFAMILY SSF53067 428 487 4.05E-25 T 05-07-2017 K08M4_RS08420 94a9745b948c6f3034b0b434591c6ae8 646 SUPERFAMILY SSF53067 19 212 7.77E-27 T 05-07-2017 K08M4_RS08420 94a9745b948c6f3034b0b434591c6ae8 646 Gene3D G3DSA:3.30.420.40 148 237 1.8E-31 T 05-07-2017 K08M4_RS08420 94a9745b948c6f3034b0b434591c6ae8 646 Gene3D G3DSA:3.30.420.40 20 109 1.8E-31 T 05-07-2017 K08M4_RS08420 94a9745b948c6f3034b0b434591c6ae8 646 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 231 244 - T 05-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 K08M4_RS08420 94a9745b948c6f3034b0b434591c6ae8 646 Gene3D G3DSA:3.30.420.40 238 330 2.0E-18 T 05-07-2017 K08M4_RS08420 94a9745b948c6f3034b0b434591c6ae8 646 PRINTS PR00301 70kDa heat shock protein signature 170 190 5.0E-7 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS08420 94a9745b948c6f3034b0b434591c6ae8 646 PRINTS PR00301 70kDa heat shock protein signature 19 32 5.0E-7 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS08420 94a9745b948c6f3034b0b434591c6ae8 646 PRINTS PR00301 70kDa heat shock protein signature 237 247 5.0E-7 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS08420 94a9745b948c6f3034b0b434591c6ae8 646 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 23 30 - T 05-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 K08M4_RS08420 94a9745b948c6f3034b0b434591c6ae8 646 Pfam PF00012 Hsp70 protein 21 345 4.0E-16 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS00375 d3e4d05c604aa22882b513b5527bb5f0 130 Pfam PF13358 DDE superfamily endonuclease 23 121 6.2E-14 T 05-07-2017 K08M4_RS13940 06ce13f8a88f94f4c84b060bf4083965 224 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 51 81 0.0011 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS13940 06ce13f8a88f94f4c84b060bf4083965 224 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 131 165 7.0E-5 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS13940 06ce13f8a88f94f4c84b060bf4083965 224 Gene3D G3DSA:2.160.10.10 50 214 1.3E-44 T 05-07-2017 K08M4_RS13940 06ce13f8a88f94f4c84b060bf4083965 224 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 05-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 K08M4_RS13940 06ce13f8a88f94f4c84b060bf4083965 224 SUPERFAMILY SSF51161 53 211 1.22E-35 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS11695 5da1ac3f5469ecf8d82113f11579e040 345 Gene3D G3DSA:2.60.120.200 32 343 3.2E-74 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain K08M4_RS11695 5da1ac3f5469ecf8d82113f11579e040 345 Pfam PF08787 Alginate lyase 41 343 5.7E-75 T 05-07-2017 IPR014895 Alginate lyase 2 K08M4_RS11695 5da1ac3f5469ecf8d82113f11579e040 345 SUPERFAMILY SSF49899 41 216 1.66E-45 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain K08M4_RS11695 5da1ac3f5469ecf8d82113f11579e040 345 SUPERFAMILY SSF49899 243 341 1.66E-45 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain K08M4_RS07790 3cd92a7a1b8236c7ff689ce02bca4056 86 Gene3D G3DSA:3.40.30.10 2 84 2.3E-26 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS07790 3cd92a7a1b8236c7ff689ce02bca4056 86 SUPERFAMILY SSF52833 1 79 6.41E-13 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS07790 3cd92a7a1b8236c7ff689ce02bca4056 86 Pfam PF05768 Glutaredoxin-like domain (DUF836) 2 78 8.4E-19 T 05-07-2017 IPR008554 Glutaredoxin-like K08M4_RS20385 bc7970216dd38ea0ad28f5203ffe8016 421 Pfam PF01966 HD domain 33 145 2.8E-7 T 05-07-2017 IPR006674 HD domain K08M4_RS20385 bc7970216dd38ea0ad28f5203ffe8016 421 Pfam PF01966 HD domain 244 365 6.7E-20 T 05-07-2017 IPR006674 HD domain K08M4_RS20385 bc7970216dd38ea0ad28f5203ffe8016 421 SMART SM00471 240 375 1.0E-10 T 05-07-2017 IPR003607 HD/PDEase domain K08M4_RS20385 bc7970216dd38ea0ad28f5203ffe8016 421 SMART SM00471 26 155 5.5 T 05-07-2017 IPR003607 HD/PDEase domain K08M4_RS20385 bc7970216dd38ea0ad28f5203ffe8016 421 SUPERFAMILY SSF109604 17 190 2.04E-15 T 05-07-2017 K08M4_RS20385 bc7970216dd38ea0ad28f5203ffe8016 421 Gene3D G3DSA:1.10.3210.10 31 206 7.3E-16 T 05-07-2017 IPR006674 HD domain K08M4_RS20385 bc7970216dd38ea0ad28f5203ffe8016 421 Gene3D G3DSA:1.10.3210.10 230 401 2.9E-27 T 05-07-2017 IPR006674 HD domain K08M4_RS20385 bc7970216dd38ea0ad28f5203ffe8016 421 SUPERFAMILY SSF109604 237 405 7.66E-31 T 05-07-2017 K08M4_RS08505 a01c5120a8496537a2174bebb068aa58 380 PRINTS PR00166 Aromatic amino acid permease signature 33 52 1.2E-28 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS08505 a01c5120a8496537a2174bebb068aa58 380 PRINTS PR00166 Aromatic amino acid permease signature 302 320 1.2E-28 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS08505 a01c5120a8496537a2174bebb068aa58 380 PRINTS PR00166 Aromatic amino acid permease signature 323 342 1.2E-28 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS08505 a01c5120a8496537a2174bebb068aa58 380 PRINTS PR00166 Aromatic amino acid permease signature 6 29 1.2E-28 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS08505 a01c5120a8496537a2174bebb068aa58 380 PRINTS PR00166 Aromatic amino acid permease signature 78 98 1.2E-28 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS08505 a01c5120a8496537a2174bebb068aa58 380 PRINTS PR00166 Aromatic amino acid permease signature 178 200 1.2E-28 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS08505 a01c5120a8496537a2174bebb068aa58 380 PRINTS PR00166 Aromatic amino acid permease signature 143 163 1.2E-28 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS08505 a01c5120a8496537a2174bebb068aa58 380 Pfam PF03222 Tryptophan/tyrosine permease family 1 376 9.3E-76 T 05-07-2017 IPR018227 Tryptophan/tyrosine permease GO:0003333 K08M4_RS01850 efc78bb3866e396ef18dffb82f73af58 259 Pfam PF02405 Permease MlaE 44 255 4.8E-75 T 05-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 K08M4_RS01850 efc78bb3866e396ef18dffb82f73af58 259 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 6 257 1.1E-96 T 05-07-2017 IPR003453 ABC transport permease subunit MlaE, Proteobacteria K08M4_RS07930 9fe1dbdb3e67226d99b1def3b7a25f13 95 Pfam PF00708 Acylphosphatase 4 94 8.9E-22 T 05-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 K08M4_RS07930 9fe1dbdb3e67226d99b1def3b7a25f13 95 SUPERFAMILY SSF54975 3 83 1.57E-23 T 05-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 K08M4_RS07930 9fe1dbdb3e67226d99b1def3b7a25f13 95 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 05-07-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 K08M4_RS07930 9fe1dbdb3e67226d99b1def3b7a25f13 95 Gene3D G3DSA:3.30.70.100 5 83 2.1E-23 T 05-07-2017 K08M4_RS20120 b857983d9594cb419b9a5a9f64ebfe82 145 Pfam PF00989 PAS fold 16 134 2.5E-6 T 05-07-2017 IPR013767 PAS fold GO:0006355 K08M4_RS20120 b857983d9594cb419b9a5a9f64ebfe82 145 SUPERFAMILY SSF55785 10 129 4.54E-10 T 05-07-2017 IPR000014 PAS domain K08M4_RS20120 b857983d9594cb419b9a5a9f64ebfe82 145 Gene3D G3DSA:3.30.450.20 16 136 2.2E-11 T 05-07-2017 K08M4_RS18515 012435e7a6e46f1c0d55e4464e731006 219 SUPERFAMILY SSF52172 4 173 3.27E-27 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS18515 012435e7a6e46f1c0d55e4464e731006 219 SUPERFAMILY SSF46894 123 217 9.35E-29 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS18515 012435e7a6e46f1c0d55e4464e731006 219 Pfam PF00072 Response regulator receiver domain 6 112 1.3E-16 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS18515 012435e7a6e46f1c0d55e4464e731006 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 217 1.7E-23 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS18515 012435e7a6e46f1c0d55e4464e731006 219 SMART SM00862 146 217 2.2E-25 T 05-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 K08M4_RS18515 012435e7a6e46f1c0d55e4464e731006 219 Gene3D G3DSA:3.40.50.2300 3 119 1.9E-25 T 05-07-2017 K08M4_RS18515 012435e7a6e46f1c0d55e4464e731006 219 SMART SM00448 3 111 4.7E-25 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS18515 012435e7a6e46f1c0d55e4464e731006 219 Gene3D G3DSA:1.10.10.10 124 218 1.8E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS12055 3807cfc504f9fa3b9c1652e21f1f3d80 84 Gene3D G3DSA:3.30.70.20 4 71 5.6E-17 T 05-07-2017 K08M4_RS12055 3807cfc504f9fa3b9c1652e21f1f3d80 84 Pfam PF12838 4Fe-4S dicluster domain 8 55 3.8E-6 T 05-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain K08M4_RS12055 3807cfc504f9fa3b9c1652e21f1f3d80 84 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 05-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site K08M4_RS12055 3807cfc504f9fa3b9c1652e21f1f3d80 84 SUPERFAMILY SSF54862 4 66 4.93E-17 T 05-07-2017 K08M4_RS02030 50755202c74efe19a0b0f209af14f1ee 131 Pfam PF09622 Putative integral membrane protein (DUF2391) 14 125 4.0E-9 T 05-07-2017 IPR024464 Protein of unknown function DUF2391 K08M4_RS03990 5cb6658c9e9725f9b60722122d942a15 413 SUPERFAMILY SSF51905 287 391 2.14E-41 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS03990 5cb6658c9e9725f9b60722122d942a15 413 SUPERFAMILY SSF51905 6 175 2.14E-41 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS03990 5cb6658c9e9725f9b60722122d942a15 413 Gene3D G3DSA:3.50.50.60 2 180 2.0E-32 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS03990 5cb6658c9e9725f9b60722122d942a15 413 Gene3D G3DSA:3.50.50.60 283 326 2.0E-32 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS03990 5cb6658c9e9725f9b60722122d942a15 413 Pfam PF01494 FAD binding domain 6 173 2.2E-16 T 05-07-2017 IPR002938 FAD-binding domain GO:0071949 K08M4_RS13395 a3cb72decb8f2b2b0f9340ce36ccb591 103 Gene3D G3DSA:1.10.443.10 17 97 3.9E-17 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS13395 a3cb72decb8f2b2b0f9340ce36ccb591 103 Pfam PF00589 Phage integrase family 19 93 1.7E-11 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS13395 a3cb72decb8f2b2b0f9340ce36ccb591 103 SUPERFAMILY SSF56349 16 98 4.41E-18 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS14315 f9ddc733be461ae63d7eff7bc36e18ea 189 Pfam PF13511 Domain of unknown function (DUF4124) 11 58 9.0E-11 T 05-07-2017 IPR025392 Domain of unknown function DUF4124 K08M4_RS20205 7cf0d225aa37799cdab79c5131e36442 678 Gene3D G3DSA:2.170.130.10 47 169 1.8E-35 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS20205 7cf0d225aa37799cdab79c5131e36442 678 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 162 2.1E-22 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS20205 7cf0d225aa37799cdab79c5131e36442 678 SUPERFAMILY SSF56935 25 678 2.33E-120 T 05-07-2017 K08M4_RS20205 7cf0d225aa37799cdab79c5131e36442 678 Gene3D G3DSA:2.40.170.20 176 678 1.3E-112 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS20205 7cf0d225aa37799cdab79c5131e36442 678 Pfam PF00593 TonB dependent receptor 452 676 2.0E-23 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS20205 7cf0d225aa37799cdab79c5131e36442 678 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 66 678 8.3E-87 T 05-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 K08M4_RS04440 d8b211a545cc4e5f3ecd5dc46ec37732 220 Gene3D G3DSA:2.160.20.70 101 217 4.3E-36 T 05-07-2017 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 K08M4_RS04440 d8b211a545cc4e5f3ecd5dc46ec37732 220 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 4 219 27.621 T 05-07-2017 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 K08M4_RS04440 d8b211a545cc4e5f3ecd5dc46ec37732 220 SUPERFAMILY SSF63848 113 216 4.84E-29 T 05-07-2017 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 K08M4_RS04440 d8b211a545cc4e5f3ecd5dc46ec37732 220 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 1 102 1.6E-30 T 05-07-2017 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 K08M4_RS04440 d8b211a545cc4e5f3ecd5dc46ec37732 220 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 115 215 1.8E-30 T 05-07-2017 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 K08M4_RS04440 d8b211a545cc4e5f3ecd5dc46ec37732 220 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 5 216 2.1E-75 T 05-07-2017 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 K08M4_RS21825 1faf1f9ad0e27e5a18b72a56098738da 391 Gene3D G3DSA:2.60.120.10 216 352 6.7E-30 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS21825 1faf1f9ad0e27e5a18b72a56098738da 391 Gene3D G3DSA:2.60.120.10 67 165 1.9E-23 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS21825 1faf1f9ad0e27e5a18b72a56098738da 391 SUPERFAMILY SSF51182 56 375 2.15E-90 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS21825 1faf1f9ad0e27e5a18b72a56098738da 391 Pfam PF04209 homogentisate 1,2-dioxygenase 85 375 1.1E-21 T 05-07-2017 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 K08M4_RS10545 f1c7372b249ab68d37cd511f4bc9e112 259 SUPERFAMILY SSF52540 2 228 3.06E-53 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10545 f1c7372b249ab68d37cd511f4bc9e112 259 Pfam PF00005 ABC transporter 20 148 2.8E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS10545 f1c7372b249ab68d37cd511f4bc9e112 259 Gene3D G3DSA:3.40.50.300 2 216 7.9E-55 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10545 f1c7372b249ab68d37cd511f4bc9e112 259 SMART SM00382 29 199 2.3E-7 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS05175 499303e409309e0b1dbda15d187fc024 486 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 84 110 3.1E-36 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS05175 499303e409309e0b1dbda15d187fc024 486 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 40 59 3.1E-36 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS05175 499303e409309e0b1dbda15d187fc024 486 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 311 330 3.1E-36 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS05175 499303e409309e0b1dbda15d187fc024 486 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 429 449 3.1E-36 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS05175 499303e409309e0b1dbda15d187fc024 486 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 257 277 3.1E-36 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS05175 499303e409309e0b1dbda15d187fc024 486 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 388 408 3.1E-36 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS05175 499303e409309e0b1dbda15d187fc024 486 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 11 32 3.1E-36 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS05175 499303e409309e0b1dbda15d187fc024 486 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 27 41 - T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS05175 499303e409309e0b1dbda15d187fc024 486 SUPERFAMILY SSF161070 3 475 5.23E-146 T 05-07-2017 K08M4_RS05175 499303e409309e0b1dbda15d187fc024 486 Pfam PF00209 Sodium:neurotransmitter symporter family 123 473 1.9E-75 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS17840 ac0316eace5a59c274b836a44427c3f1 101 Pfam PF03927 NapD protein 6 80 6.7E-28 T 05-07-2017 IPR005623 Chaperone NapD, nitrate reductase assembly K08M4_RS05285 fdc1e5637921dabe2836d920c0a045cf 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 217 6.9E-19 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS05285 fdc1e5637921dabe2836d920c0a045cf 225 Gene3D G3DSA:1.10.3720.10 11 217 1.8E-41 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS05285 fdc1e5637921dabe2836d920c0a045cf 225 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 112 4.5E-22 T 05-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 K08M4_RS05285 fdc1e5637921dabe2836d920c0a045cf 225 SUPERFAMILY SSF161098 11 203 3.92E-40 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS04180 533097f9b1e2af0ece09c6fd39832ad7 704 Pfam PF02120 Flagellar hook-length control protein FliK 576 659 2.8E-23 T 05-07-2017 IPR021136 Flagellar hook-length control protein-like, C-terminal K08M4_RS20280 fa63da0eea2d946695c6fc8d930b1c0a 350 SUPERFAMILY SSF51430 1 349 1.18E-93 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain K08M4_RS20280 fa63da0eea2d946695c6fc8d930b1c0a 350 Gene3D G3DSA:3.20.20.100 1 348 5.2E-90 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain K08M4_RS20280 fa63da0eea2d946695c6fc8d930b1c0a 350 Pfam PF00248 Aldo/keto reductase family 15 340 1.5E-63 T 05-07-2017 IPR023210 NADP-dependent oxidoreductase domain K08M4_RS20280 fa63da0eea2d946695c6fc8d930b1c0a 350 PRINTS PR00069 Aldo-keto reductase signature 168 185 3.0E-6 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 K08M4_RS20280 fa63da0eea2d946695c6fc8d930b1c0a 350 PRINTS PR00069 Aldo-keto reductase signature 114 132 3.0E-6 T 05-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 K08M4_RS07315 d303f10fa94160d03fc64d0d9cc72cad 219 Pfam PF02397 Bacterial sugar transferase 21 214 7.7E-52 T 05-07-2017 IPR003362 Bacterial sugar transferase K08M4_RS16385 35402e654a432483f300da602e5e67ad 92 Pfam PF13616 PPIC-type PPIASE domain 14 89 3.9E-21 T 05-07-2017 K08M4_RS16385 35402e654a432483f300da602e5e67ad 92 Gene3D G3DSA:3.10.50.40 5 91 8.5E-33 T 05-07-2017 K08M4_RS16385 35402e654a432483f300da602e5e67ad 92 SUPERFAMILY SSF54534 6 89 5.43E-24 T 05-07-2017 K08M4_RS01120 7b350c22bf1436afc38c9079eba85ac4 172 TIGRFAM TIGR02998 RraA_entero: regulator of ribonuclease activity A 1 161 1.7E-81 T 05-07-2017 IPR014339 Regulator of ribonuclease activity A, gammaproteobacteria GO:0008428|GO:0051252 K08M4_RS01120 7b350c22bf1436afc38c9079eba85ac4 172 TIGRFAM TIGR01935 NOT-MenG: RraA family 5 154 1.9E-67 T 05-07-2017 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 K08M4_RS01120 7b350c22bf1436afc38c9079eba85ac4 172 Hamap MF_00471 Regulator of ribonuclease activity A [rraA]. 1 161 47.139 T 05-07-2017 IPR014339 Regulator of ribonuclease activity A, gammaproteobacteria GO:0008428|GO:0051252 K08M4_RS01120 7b350c22bf1436afc38c9079eba85ac4 172 Pfam PF03737 Demethylmenaquinone methyltransferase 6 152 1.0E-37 T 05-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein K08M4_RS01120 7b350c22bf1436afc38c9079eba85ac4 172 Gene3D G3DSA:3.50.30.40 1 157 2.4E-47 T 05-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein K08M4_RS01120 7b350c22bf1436afc38c9079eba85ac4 172 SUPERFAMILY SSF89562 2 158 9.03E-46 T 05-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 642 6.2E-257 T 05-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 Pfam PF01578 Cytochrome C assembly protein 89 297 6.2E-54 T 05-07-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 275 295 7.3E-95 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 160 182 7.3E-95 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 7.3E-95 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 295 311 7.3E-95 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 211 237 7.3E-95 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 245 265 7.3E-95 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 7.3E-95 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 311 330 7.3E-95 T 05-07-2017 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 316 639 8.1E-126 T 05-07-2017 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 632 645 1.7E-61 T 05-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 1.7E-61 T 05-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 190 205 1.7E-61 T 05-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 352 369 1.7E-61 T 05-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 395 414 1.7E-61 T 05-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 314 329 1.7E-61 T 05-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04310 46f3e35a160aa2dcffb3c4a864444e4d 656 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 1.7E-61 T 05-07-2017 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS08115 af48be345ec93512726c3d7101e4187f 438 Pfam PF12698 ABC-2 family transporter protein 38 388 5.3E-46 T 05-07-2017 K08M4_RS17860 f4fe18a072665ae4538e723282d455db 455 Pfam PF03606 C4-dicarboxylate anaerobic carrier 2 451 1.6E-124 T 05-07-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 K08M4_RS17860 f4fe18a072665ae4538e723282d455db 455 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 55 441 1.0E-141 T 05-07-2017 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 K08M4_RS19165 10d579fc88b105e556debdf3fa2a2196 743 Gene3D G3DSA:3.40.50.2300 613 740 8.0E-35 T 05-07-2017 K08M4_RS19165 10d579fc88b105e556debdf3fa2a2196 743 SUPERFAMILY SSF52172 617 737 4.13E-30 T 05-07-2017 IPR011006 CheY-like superfamily K08M4_RS19165 10d579fc88b105e556debdf3fa2a2196 743 Pfam PF00072 Response regulator receiver domain 620 734 3.4E-23 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS19165 10d579fc88b105e556debdf3fa2a2196 743 SMART SM00448 617 733 3.7E-26 T 05-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 K08M4_RS10615 d2471221f982e1e208a80b37a6a5543a 179 Gene3D G3DSA:1.10.1220.10 1 38 3.8E-23 T 05-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 K08M4_RS10615 d2471221f982e1e208a80b37a6a5543a 179 Hamap MF_00908 Negative modulator of initiation of replication [seqA]. 1 179 40.247 T 05-07-2017 IPR005621 Negative modulator of initiation of replicationr SeqA GO:0003677|GO:0032297 K08M4_RS10615 d2471221f982e1e208a80b37a6a5543a 179 SUPERFAMILY SSF82808 65 178 4.32E-47 T 05-07-2017 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 K08M4_RS10615 d2471221f982e1e208a80b37a6a5543a 179 Pfam PF03925 SeqA protein C-terminal domain 70 177 6.5E-46 T 05-07-2017 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 K08M4_RS10615 d2471221f982e1e208a80b37a6a5543a 179 SUPERFAMILY SSF47598 1 33 3.78E-12 T 05-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 K08M4_RS10615 d2471221f982e1e208a80b37a6a5543a 179 Gene3D G3DSA:1.20.1380.10 68 179 3.0E-50 T 05-07-2017 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 K08M4_RS10625 28eb049b57ad247b7ae649dab8b42ac9 72 Pfam PF10981 Protein of unknown function (DUF2788) 18 67 5.6E-19 T 05-07-2017 IPR021249 Protein of unknown function DUF2788 K08M4_RS18950 e697b7b97372c09aaee9ef0298cd44de 105 Pfam PF01381 Helix-turn-helix 11 60 3.2E-10 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 K08M4_RS18950 e697b7b97372c09aaee9ef0298cd44de 105 SMART SM00530 9 64 2.1E-7 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 K08M4_RS18950 e697b7b97372c09aaee9ef0298cd44de 105 Gene3D G3DSA:1.10.260.40 9 60 4.5E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS18950 e697b7b97372c09aaee9ef0298cd44de 105 SUPERFAMILY SSF47413 1 64 8.58E-11 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS21670 3238266aafd0e2ad9ab37e187f218ad0 362 SUPERFAMILY SSF51395 1 362 1.98E-120 T 05-07-2017 K08M4_RS21670 3238266aafd0e2ad9ab37e187f218ad0 362 Gene3D G3DSA:3.20.20.70 1 361 2.8E-130 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS21670 3238266aafd0e2ad9ab37e187f218ad0 362 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 339 1.5E-92 T 05-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 K08M4_RS17795 e1fd72393c02ab8e6c324afc44f345b6 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 05-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site K08M4_RS17795 e1fd72393c02ab8e6c324afc44f345b6 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 47 1.4E-20 T 05-07-2017 K08M4_RS17795 e1fd72393c02ab8e6c324afc44f345b6 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.5E-19 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS17795 e1fd72393c02ab8e6c324afc44f345b6 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.5E-19 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS17795 e1fd72393c02ab8e6c324afc44f345b6 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.5E-19 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS17795 e1fd72393c02ab8e6c324afc44f345b6 152 Gene3D G3DSA:3.30.70.920 54 137 1.1E-25 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS17795 e1fd72393c02ab8e6c324afc44f345b6 152 SUPERFAMILY SSF46785 1 60 3.04E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS17795 e1fd72393c02ab8e6c324afc44f345b6 152 Gene3D G3DSA:1.10.10.10 2 52 3.6E-25 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS17795 e1fd72393c02ab8e6c324afc44f345b6 152 SMART SM00344 1 110 3.8E-45 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 K08M4_RS17795 e1fd72393c02ab8e6c324afc44f345b6 152 SUPERFAMILY SSF54909 63 149 1.13E-19 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel K08M4_RS17795 e1fd72393c02ab8e6c324afc44f345b6 152 Pfam PF01037 Lrp/AsnC ligand binding domain 67 139 1.9E-20 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS20895 80ed65cf7d76c8c455bc0ef26dfc11f7 278 SUPERFAMILY SSF52266 89 277 6.72E-45 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain K08M4_RS20895 80ed65cf7d76c8c455bc0ef26dfc11f7 278 Gene3D G3DSA:3.40.50.1110 105 277 3.1E-41 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain K08M4_RS20895 80ed65cf7d76c8c455bc0ef26dfc11f7 278 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 113 264 3.7E-23 T 05-07-2017 IPR013830 SGNH hydrolase-type esterase domain K08M4_RS03625 ad52accd7c52a4ca3aaa515eb72bd58b 105 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 1.6E-36 T 05-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS K08M4_RS03625 ad52accd7c52a4ca3aaa515eb72bd58b 105 SUPERFAMILY SSF81301 5 105 1.8E-35 T 05-07-2017 K08M4_RS03625 ad52accd7c52a4ca3aaa515eb72bd58b 105 Pfam PF02410 Ribosomal silencing factor during starvation 11 104 3.2E-26 T 05-07-2017 K08M4_RS03625 ad52accd7c52a4ca3aaa515eb72bd58b 105 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 2 105 23.819 T 05-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS K08M4_RS03625 ad52accd7c52a4ca3aaa515eb72bd58b 105 Gene3D G3DSA:3.30.460.10 4 105 1.7E-36 T 05-07-2017 K08M4_RS16190 57f569698648388ee30779818e793bc1 395 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 224 382 4.1E-37 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS16190 57f569698648388ee30779818e793bc1 395 Pfam PF00990 Diguanylate cyclase, GGDEF domain 227 380 1.4E-35 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS16190 57f569698648388ee30779818e793bc1 395 SMART SM00267 215 385 2.3E-38 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS16190 57f569698648388ee30779818e793bc1 395 SUPERFAMILY SSF55073 231 384 2.43E-38 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS16190 57f569698648388ee30779818e793bc1 395 Gene3D G3DSA:3.30.70.270 228 386 2.5E-41 T 05-07-2017 K08M4_RS14040 2eb10c849ef389b1ca08949c3dae5eca 213 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 10 187 1.0E-68 T 05-07-2017 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS14040 2eb10c849ef389b1ca08949c3dae5eca 213 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 213 36.053 T 05-07-2017 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 K08M4_RS14040 2eb10c849ef389b1ca08949c3dae5eca 213 Pfam PF00156 Phosphoribosyl transferase domain 43 161 2.4E-12 T 05-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 K08M4_RS14040 2eb10c849ef389b1ca08949c3dae5eca 213 Gene3D G3DSA:3.40.50.2020 7 212 1.8E-83 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS14040 2eb10c849ef389b1ca08949c3dae5eca 213 SUPERFAMILY SSF53271 2 211 5.96E-50 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS19885 b75fc050b4289383a11a8bd1a41d7fe8 91 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 9 82 1.6E-11 T 05-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 K08M4_RS19885 b75fc050b4289383a11a8bd1a41d7fe8 91 Gene3D G3DSA:3.20.20.70 6 89 1.7E-23 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS19885 b75fc050b4289383a11a8bd1a41d7fe8 91 SUPERFAMILY SSF51412 7 80 4.58E-17 T 05-07-2017 K08M4_RS19250 8a9db8d31b373e990f2d1d2ce87146d3 320 Pfam PF01882 Protein of unknown function DUF58 58 143 2.3E-20 T 05-07-2017 IPR002881 Domain of unknown function DUF58 K08M4_RS19250 8a9db8d31b373e990f2d1d2ce87146d3 320 SUPERFAMILY SSF53300 94 251 4.45E-6 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS11780 0dd8a10b84ed7988e5211d317a490284 515 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 86 101 - T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS11780 0dd8a10b84ed7988e5211d317a490284 515 Pfam PF01235 Sodium:alanine symporter family 51 472 1.3E-148 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS11780 0dd8a10b84ed7988e5211d317a490284 515 PRINTS PR00175 Sodium/alanine symporter signature 428 448 8.2E-57 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS11780 0dd8a10b84ed7988e5211d317a490284 515 PRINTS PR00175 Sodium/alanine symporter signature 189 207 8.2E-57 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS11780 0dd8a10b84ed7988e5211d317a490284 515 PRINTS PR00175 Sodium/alanine symporter signature 365 387 8.2E-57 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS11780 0dd8a10b84ed7988e5211d317a490284 515 PRINTS PR00175 Sodium/alanine symporter signature 86 108 8.2E-57 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS11780 0dd8a10b84ed7988e5211d317a490284 515 PRINTS PR00175 Sodium/alanine symporter signature 217 236 8.2E-57 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS11780 0dd8a10b84ed7988e5211d317a490284 515 PRINTS PR00175 Sodium/alanine symporter signature 304 322 8.2E-57 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS11780 0dd8a10b84ed7988e5211d317a490284 515 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 462 1.6E-133 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS13700 23176a8119924c8b84f9addf674039fe 162 Pfam PF02308 MgtC family 19 141 8.3E-28 T 05-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 K08M4_RS13700 23176a8119924c8b84f9addf674039fe 162 PRINTS PR01837 MgtC/SapB protein signature 22 41 3.1E-31 T 05-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 K08M4_RS13700 23176a8119924c8b84f9addf674039fe 162 PRINTS PR01837 MgtC/SapB protein signature 41 59 3.1E-31 T 05-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 K08M4_RS13700 23176a8119924c8b84f9addf674039fe 162 PRINTS PR01837 MgtC/SapB protein signature 68 90 3.1E-31 T 05-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 K08M4_RS13700 23176a8119924c8b84f9addf674039fe 162 PRINTS PR01837 MgtC/SapB protein signature 95 119 3.1E-31 T 05-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 K08M4_RS07370 181a61a591bd8316bd56565fdbd0f4c4 299 Gene3D G3DSA:1.10.3720.10 96 278 1.4E-38 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07370 181a61a591bd8316bd56565fdbd0f4c4 299 SUPERFAMILY SSF161098 99 281 1.31E-38 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07370 181a61a591bd8316bd56565fdbd0f4c4 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 278 4.2E-28 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS04685 26812123f599dc845e23c84faeacdb57 268 Pfam PF11207 Protein of unknown function (DUF2989) 13 215 2.7E-73 T 05-07-2017 IPR021372 Protein of unknown function DUF2989 K08M4_RS14250 3923d6344ec382eb626946117daf3e9d 307 Pfam PF11356 Type II secretion system protein C 37 175 3.8E-44 T 05-07-2017 IPR024961 Type II secretion system protein C, N-terminal K08M4_RS14250 3923d6344ec382eb626946117daf3e9d 307 Gene3D G3DSA:2.30.42.10 251 303 3.5E-6 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS14250 3923d6344ec382eb626946117daf3e9d 307 TIGRFAM TIGR01713 typeII_sec_gspC: type II secretion system protein C 34 307 9.0E-77 T 05-07-2017 IPR001639 Type II secretion system protein C GO:0008565|GO:0015627|GO:0015628 K08M4_RS14250 3923d6344ec382eb626946117daf3e9d 307 SUPERFAMILY SSF50156 213 306 2.22E-17 T 05-07-2017 IPR001478 PDZ domain GO:0005515 K08M4_RS09755 127d5631d7f5af7fad5384969918e200 251 Gene3D G3DSA:1.20.1260.10 104 251 7.4E-86 T 05-07-2017 IPR012347 Ferritin-related K08M4_RS09755 127d5631d7f5af7fad5384969918e200 251 Gene3D G3DSA:1.20.1260.10 3 56 7.4E-86 T 05-07-2017 IPR012347 Ferritin-related K08M4_RS09755 127d5631d7f5af7fad5384969918e200 251 Pfam PF06175 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) 5 247 1.2E-105 T 05-07-2017 IPR010386 tRNA-hydroxylase MiaE GO:0006400|GO:0045301 K08M4_RS09755 127d5631d7f5af7fad5384969918e200 251 SUPERFAMILY SSF47240 6 56 2.08E-73 T 05-07-2017 IPR009078 Ferritin-like superfamily K08M4_RS09755 127d5631d7f5af7fad5384969918e200 251 SUPERFAMILY SSF47240 104 251 2.08E-73 T 05-07-2017 IPR009078 Ferritin-like superfamily K08M4_RS09755 127d5631d7f5af7fad5384969918e200 251 PIRSF PIRSF020736 1 251 1.7E-88 T 05-07-2017 IPR010386 tRNA-hydroxylase MiaE GO:0006400|GO:0045301 K08M4_RS19300 6d048270fbc8d1bb718da1affdd7e714 167 Pfam PF10688 Bacterial inner membrane protein 6 162 2.1E-47 T 05-07-2017 IPR019629 Uncharacterised protein family HI1736/YgjV K08M4_RS19300 6d048270fbc8d1bb718da1affdd7e714 167 PIRSF PIRSF011443 1 166 4.1E-54 T 05-07-2017 IPR026267 Inner membrane protein YgjV K08M4_RS16940 bd0c7d78cd0939c6404dc580203b24ba 165 Pfam PF01202 Shikimate kinase 12 162 7.9E-19 T 05-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 K08M4_RS16940 bd0c7d78cd0939c6404dc580203b24ba 165 SUPERFAMILY SSF52540 3 163 2.63E-23 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS16940 bd0c7d78cd0939c6404dc580203b24ba 165 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 6 162 4.5E-54 T 05-07-2017 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 K08M4_RS16940 bd0c7d78cd0939c6404dc580203b24ba 165 Gene3D G3DSA:3.40.50.300 2 164 3.4E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19400 bba97821d646d8262f6355d9a6319aa7 293 SUPERFAMILY SSF46785 2 111 1.22E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19400 bba97821d646d8262f6355d9a6319aa7 293 Gene3D G3DSA:1.10.10.10 3 87 1.0E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS19400 bba97821d646d8262f6355d9a6319aa7 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.7E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS19400 bba97821d646d8262f6355d9a6319aa7 293 Gene3D G3DSA:3.40.190.10 182 263 7.4E-7 T 05-07-2017 K08M4_RS19400 bba97821d646d8262f6355d9a6319aa7 293 SUPERFAMILY SSF53850 89 290 2.0E-34 T 05-07-2017 K08M4_RS19400 bba97821d646d8262f6355d9a6319aa7 293 Gene3D G3DSA:3.40.190.10 89 181 4.6E-24 T 05-07-2017 K08M4_RS19400 bba97821d646d8262f6355d9a6319aa7 293 Pfam PF03466 LysR substrate binding domain 88 288 3.9E-37 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS16980 f966ac4c42d9a5072558534065b52739 84 Pfam PF03891 Domain of unknown function (DUF333) 32 76 1.8E-18 T 05-07-2017 IPR005590 Protein of unknown function DUF333 K08M4_RS00975 f9e9f8eb277999bd3140d7b63b37af47 88 Pfam PF13937 Domain of unknown function (DUF4212) 9 85 1.8E-35 T 05-07-2017 IPR019886 Sodium symporter small subunit, predicted K08M4_RS00975 f9e9f8eb277999bd3140d7b63b37af47 88 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 11 87 8.5E-36 T 05-07-2017 IPR019886 Sodium symporter small subunit, predicted K08M4_RS10600 a01e11d31bf6d76722ac342e33dca80f 252 SUPERFAMILY SSF102705 1 251 1.27E-82 T 05-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 K08M4_RS10600 a01e11d31bf6d76722ac342e33dca80f 252 Gene3D G3DSA:3.40.1390.30 108 219 2.6E-30 T 05-07-2017 K08M4_RS10600 a01e11d31bf6d76722ac342e33dca80f 252 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 251 8.3E-71 T 05-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 K08M4_RS10600 a01e11d31bf6d76722ac342e33dca80f 252 Gene3D G3DSA:3.40.1390.30 1 107 5.9E-39 T 05-07-2017 K08M4_RS10600 a01e11d31bf6d76722ac342e33dca80f 252 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 238 1.3E-60 T 05-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 K08M4_RS14735 356cfe077cfb49e3c4e068dcbbe2e242 181 SUPERFAMILY SSF51161 4 175 9.01E-46 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS14735 356cfe077cfb49e3c4e068dcbbe2e242 181 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 40 1.1E-5 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS14735 356cfe077cfb49e3c4e068dcbbe2e242 181 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 96 129 1.6E-6 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS14735 356cfe077cfb49e3c4e068dcbbe2e242 181 Gene3D G3DSA:2.160.10.10 4 175 7.2E-45 T 05-07-2017 K08M4_RS18785 a765fe96f038287de69aa97c1edbc525 572 Gene3D G3DSA:2.40.160.50 281 572 2.2E-15 T 05-07-2017 K08M4_RS18785 a765fe96f038287de69aa97c1edbc525 572 Pfam PF01103 Surface antigen 269 572 1.3E-24 T 05-07-2017 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020 K08M4_RS17395 eff557d7eebdcf45124243175daa7bbe 715 SUPERFAMILY SSF56935 23 715 1.26E-139 T 05-07-2017 K08M4_RS17395 eff557d7eebdcf45124243175daa7bbe 715 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 60 715 1.9E-122 T 05-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 K08M4_RS17395 eff557d7eebdcf45124243175daa7bbe 715 Pfam PF00593 TonB dependent receptor 472 697 5.4E-34 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS17395 eff557d7eebdcf45124243175daa7bbe 715 Gene3D G3DSA:2.170.130.10 32 172 1.6E-33 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS17395 eff557d7eebdcf45124243175daa7bbe 715 Gene3D G3DSA:2.40.170.20 176 715 7.1E-145 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS17395 eff557d7eebdcf45124243175daa7bbe 715 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 161 5.7E-19 T 05-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 K08M4_RS17395 eff557d7eebdcf45124243175daa7bbe 715 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 45 - T 05-07-2017 IPR010916 TonB box, conserved site K08M4_RS14835 ba849e84f35ae0771171344585354a9e 87 ProDom PD029038 YIHD CYTOPLASMIC ENZYME Y3814 GLYCOGEN YPO0013A HI0845 DIRECT ORF1 UNCHARACTERIZED 1 87 1.0E-35 T 05-07-2017 IPR009383 Protein of unknown function DUF1040 K08M4_RS14835 ba849e84f35ae0771171344585354a9e 87 Pfam PF06288 Protein of unknown function (DUF1040) 1 86 7.4E-45 T 05-07-2017 IPR009383 Protein of unknown function DUF1040 K08M4_RS09680 83bb7afa06ee088be49fe1a1a8511368 267 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 21 266 7.3E-65 T 05-07-2017 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 K08M4_RS09680 83bb7afa06ee088be49fe1a1a8511368 267 Gene3D G3DSA:3.40.50.150 19 247 1.1E-39 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS09680 83bb7afa06ee088be49fe1a1a8511368 267 Pfam PF08241 Methyltransferase domain 57 150 1.2E-23 T 05-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 K08M4_RS09680 83bb7afa06ee088be49fe1a1a8511368 267 SUPERFAMILY SSF53335 19 219 8.52E-41 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS09680 83bb7afa06ee088be49fe1a1a8511368 267 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 13 267 31.74 T 05-07-2017 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 K08M4_RS08885 81c8ab81681fce3e4041664fde1fc0b7 131 Pfam PF11948 Protein of unknown function (DUF3465) 10 131 1.9E-60 T 05-07-2017 IPR021856 Protein of unknown function DUF3465 K08M4_RS06575 73d031c919f1f0e138e5e7aab685d21d 342 Hamap MF_00767 Succinylglutamate desuccinylase [astE]. 1 342 130.148 T 05-07-2017 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96 K08M4_RS06575 73d031c919f1f0e138e5e7aab685d21d 342 Gene3D G3DSA:3.40.630.10 50 238 1.6E-10 T 05-07-2017 K08M4_RS06575 73d031c919f1f0e138e5e7aab685d21d 342 PIRSF PIRSF017020 4 336 1.0E-119 T 05-07-2017 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96 K08M4_RS06575 73d031c919f1f0e138e5e7aab685d21d 342 SUPERFAMILY SSF53187 9 329 5.94E-75 T 05-07-2017 K08M4_RS06575 73d031c919f1f0e138e5e7aab685d21d 342 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 53 330 1.5E-67 T 05-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 K08M4_RS17910 bd8e61c6f179372ffdc7dfdd1055dca3 241 Gene3D G3DSA:2.60.40.360 38 148 7.4E-4 T 05-07-2017 IPR008962 PapD-like K08M4_RS17910 bd8e61c6f179372ffdc7dfdd1055dca3 241 SUPERFAMILY SSF49354 22 148 2.74E-8 T 05-07-2017 IPR008962 PapD-like K08M4_RS19710 e369797cc9aac6c795eba390acbde45b 179 Pfam PF11810 Domain of unknown function (DUF3332) 7 173 1.2E-39 T 05-07-2017 IPR021768 Protein of unknown function DUF3332 K08M4_RS04795 96300cf5268e73aa4a0be229e9621797 212 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 6 204 1.4E-67 T 05-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 K08M4_RS04795 96300cf5268e73aa4a0be229e9621797 212 Pfam PF01914 MarC family integral membrane protein 8 208 2.7E-66 T 05-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 K08M4_RS10205 04191e9d5792810252650663b387714c 100 SUPERFAMILY SSF46767 2 84 2.75E-24 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 K08M4_RS10205 04191e9d5792810252650663b387714c 100 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 5 83 6.9E-23 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 K08M4_RS10205 04191e9d5792810252650663b387714c 100 Gene3D G3DSA:1.10.10.10 3 87 5.3E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS14070 e771bd42910859479b89862b4ac9d9bd 243 SUPERFAMILY SSF51366 1 223 1.1E-37 T 05-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 K08M4_RS14070 e771bd42910859479b89862b4ac9d9bd 243 Gene3D G3DSA:3.20.20.70 1 230 1.4E-38 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS14070 e771bd42910859479b89862b4ac9d9bd 243 Pfam PF00834 Ribulose-phosphate 3 epimerase family 5 209 3.7E-27 T 05-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 K08M4_RS02275 240e09519d3514dc5a7e73a89665642e 318 SUPERFAMILY SSF53807 38 311 2.75E-45 T 05-07-2017 K08M4_RS02275 240e09519d3514dc5a7e73a89665642e 318 Gene3D G3DSA:3.40.50.1980 180 311 1.6E-30 T 05-07-2017 K08M4_RS02275 240e09519d3514dc5a7e73a89665642e 318 Pfam PF01497 Periplasmic binding protein 50 285 5.5E-26 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 K08M4_RS02275 240e09519d3514dc5a7e73a89665642e 318 Gene3D G3DSA:3.40.50.1980 38 176 9.1E-11 T 05-07-2017 K08M4_RS10635 cdc4f2c6970f379b0f5ce0ed252ac381 168 Gene3D G3DSA:3.10.129.10 11 156 2.0E-35 T 05-07-2017 IPR029069 HotDog domain K08M4_RS10635 cdc4f2c6970f379b0f5ce0ed252ac381 168 Pfam PF14539 Domain of unknown function (DUF4442) 15 151 2.9E-25 T 05-07-2017 IPR027961 Protein of unknown function DUF4442 K08M4_RS10635 cdc4f2c6970f379b0f5ce0ed252ac381 168 SUPERFAMILY SSF54637 10 156 4.75E-22 T 05-07-2017 IPR029069 HotDog domain K08M4_RS09275 3826e2fc8a86d36e4aae88a933c09b82 317 Gene3D G3DSA:3.40.50.150 46 310 7.2E-58 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS09275 3826e2fc8a86d36e4aae88a933c09b82 317 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 25 310 1.8E-175 T 05-07-2017 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 K08M4_RS09275 3826e2fc8a86d36e4aae88a933c09b82 317 SUPERFAMILY SSF53335 10 286 3.9E-51 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS07465 bf1a0d03223d8d042e20ad6af1140a71 194 Gene3D G3DSA:3.90.550.10 6 190 4.8E-54 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS07465 bf1a0d03223d8d042e20ad6af1140a71 194 Pfam PF12804 MobA-like NTP transferase domain 10 158 1.2E-34 T 05-07-2017 IPR025877 MobA-like NTP transferase K08M4_RS07465 bf1a0d03223d8d042e20ad6af1140a71 194 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 8 187 2.7E-68 T 05-07-2017 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 K08M4_RS07465 bf1a0d03223d8d042e20ad6af1140a71 194 SUPERFAMILY SSF53448 10 187 3.0E-32 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS07465 bf1a0d03223d8d042e20ad6af1140a71 194 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 5 190 29.082 T 05-07-2017 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 K08M4_RS13040 637d24349fe9338c5939b917ae4a11db 859 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 134 667 3.7E-76 T 05-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit K08M4_RS13040 637d24349fe9338c5939b917ae4a11db 859 Pfam PF11874 Domain of unknown function (DUF3394) 674 853 1.7E-68 T 05-07-2017 IPR021814 Protein of unknown function DUF3394 K08M4_RS13040 637d24349fe9338c5939b917ae4a11db 859 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 32 724 1.7E-213 T 05-07-2017 IPR011853 TRAP transporter, 4TM/12TM fusion protein K08M4_RS21330 2aa6d50e7d6d26dedca78535b29673f9 85 Pfam PF04325 Protein of unknown function (DUF465) 29 75 7.1E-12 T 05-07-2017 IPR007420 Protein of unknown function DUF465 K08M4_RS08395 de11f942faed0ce252b0ff865799f616 693 SUPERFAMILY SSF56300 172 216 7.91E-12 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS08395 de11f942faed0ce252b0ff865799f616 693 SUPERFAMILY SSF56300 446 588 7.91E-12 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS08395 de11f942faed0ce252b0ff865799f616 693 SUPERFAMILY SSF56300 348 367 7.91E-12 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS08395 de11f942faed0ce252b0ff865799f616 693 Gene3D G3DSA:3.60.21.10 309 310 1.1E-4 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS08395 de11f942faed0ce252b0ff865799f616 693 Gene3D G3DSA:3.60.21.10 353 366 1.1E-4 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS08395 de11f942faed0ce252b0ff865799f616 693 Gene3D G3DSA:3.60.21.10 164 198 1.1E-4 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS08395 de11f942faed0ce252b0ff865799f616 693 Gene3D G3DSA:3.60.21.10 441 498 1.1E-4 T 05-07-2017 IPR029052 Metallo-dependent phosphatase-like K08M4_RS08820 f9983aac15933df799f10b56ad33b6f8 28 Pfam PF11665 Protein of unknown function (DUF3265) 9 28 6.0E-8 T 05-07-2017 IPR021681 Protein of unknown function DUF3265 K08M4_RS15545 caea0ad685bc6285a025daef630ce4eb 467 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 364 388 1.8E-53 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS15545 caea0ad685bc6285a025daef630ce4eb 467 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 431 446 1.8E-53 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS15545 caea0ad685bc6285a025daef630ce4eb 467 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 104 124 1.8E-53 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS15545 caea0ad685bc6285a025daef630ce4eb 467 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 331 352 1.8E-53 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS15545 caea0ad685bc6285a025daef630ce4eb 467 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 62 85 1.8E-53 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS15545 caea0ad685bc6285a025daef630ce4eb 467 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 388 411 1.8E-53 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS15545 caea0ad685bc6285a025daef630ce4eb 467 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 446 466 1.8E-53 T 05-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 K08M4_RS15545 caea0ad685bc6285a025daef630ce4eb 467 Pfam PF13437 HlyD family secretion protein 319 434 3.7E-19 T 05-07-2017 K08M4_RS15545 caea0ad685bc6285a025daef630ce4eb 467 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 51 467 1.0E-126 T 05-07-2017 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 K08M4_RS15545 caea0ad685bc6285a025daef630ce4eb 467 Gene3D G3DSA:2.40.50.100 316 350 5.9E-12 T 05-07-2017 K08M4_RS15545 caea0ad685bc6285a025daef630ce4eb 467 Gene3D G3DSA:2.40.50.100 96 126 5.9E-12 T 05-07-2017 K08M4_RS04075 e2ddd01e1fb1adfe993274804d61dd2c 363 Pfam PF02119 Flagellar P-ring protein 22 362 5.5E-134 T 05-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 K08M4_RS04075 e2ddd01e1fb1adfe993274804d61dd2c 363 PRINTS PR01010 Flagellar P-ring protein signature 22 37 5.2E-83 T 05-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 K08M4_RS04075 e2ddd01e1fb1adfe993274804d61dd2c 363 PRINTS PR01010 Flagellar P-ring protein signature 160 178 5.2E-83 T 05-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 K08M4_RS04075 e2ddd01e1fb1adfe993274804d61dd2c 363 PRINTS PR01010 Flagellar P-ring protein signature 102 119 5.2E-83 T 05-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 K08M4_RS04075 e2ddd01e1fb1adfe993274804d61dd2c 363 PRINTS PR01010 Flagellar P-ring protein signature 80 99 5.2E-83 T 05-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 K08M4_RS04075 e2ddd01e1fb1adfe993274804d61dd2c 363 PRINTS PR01010 Flagellar P-ring protein signature 186 204 5.2E-83 T 05-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 K08M4_RS04075 e2ddd01e1fb1adfe993274804d61dd2c 363 PRINTS PR01010 Flagellar P-ring protein signature 119 137 5.2E-83 T 05-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 K08M4_RS04075 e2ddd01e1fb1adfe993274804d61dd2c 363 PRINTS PR01010 Flagellar P-ring protein signature 37 52 5.2E-83 T 05-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 K08M4_RS04075 e2ddd01e1fb1adfe993274804d61dd2c 363 PRINTS PR01010 Flagellar P-ring protein signature 54 69 5.2E-83 T 05-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 K08M4_RS04075 e2ddd01e1fb1adfe993274804d61dd2c 363 PRINTS PR01010 Flagellar P-ring protein signature 250 262 5.2E-83 T 05-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 K08M4_RS04075 e2ddd01e1fb1adfe993274804d61dd2c 363 Hamap MF_00416 Flagellar P-ring protein [flgI]. 2 363 39.004 T 05-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 K08M4_RS04790 f20be860ba958a77f26fb35837832da9 281 SUPERFAMILY SSF81324 22 235 7.85E-53 T 05-07-2017 K08M4_RS04790 f20be860ba958a77f26fb35837832da9 281 Gene3D G3DSA:1.10.287.70 24 234 8.1E-52 T 05-07-2017 K08M4_RS04790 f20be860ba958a77f26fb35837832da9 281 Pfam PF00520 Ion transport protein 24 235 2.0E-31 T 05-07-2017 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 K08M4_RS04790 f20be860ba958a77f26fb35837832da9 281 PRINTS PR00169 Potassium channel signature 58 81 2.8E-38 T 05-07-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 K08M4_RS04790 f20be860ba958a77f26fb35837832da9 281 PRINTS PR00169 Potassium channel signature 178 200 2.8E-38 T 05-07-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 K08M4_RS04790 f20be860ba958a77f26fb35837832da9 281 PRINTS PR00169 Potassium channel signature 207 233 2.8E-38 T 05-07-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 K08M4_RS04790 f20be860ba958a77f26fb35837832da9 281 PRINTS PR00169 Potassium channel signature 120 146 2.8E-38 T 05-07-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 K08M4_RS04790 f20be860ba958a77f26fb35837832da9 281 PRINTS PR00169 Potassium channel signature 16 44 2.8E-38 T 05-07-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 K08M4_RS04790 f20be860ba958a77f26fb35837832da9 281 PRINTS PR00169 Potassium channel signature 84 104 2.8E-38 T 05-07-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 K08M4_RS04790 f20be860ba958a77f26fb35837832da9 281 PRINTS PR00169 Potassium channel signature 149 172 2.8E-38 T 05-07-2017 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 K08M4_RS20590 b6cc46dba8a991c82d61eb716ffd655e 445 Pfam PF01554 MatE 22 182 5.6E-21 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS20590 b6cc46dba8a991c82d61eb716ffd655e 445 Pfam PF01554 MatE 241 392 1.3E-18 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS20590 b6cc46dba8a991c82d61eb716ffd655e 445 PIRSF PIRSF006603 1 443 9.4E-88 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS20590 b6cc46dba8a991c82d61eb716ffd655e 445 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 404 3.2E-45 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS07970 fb75ce96280d0f24d881b731fa27c131 231 SUPERFAMILY SSF52402 1 211 3.31E-65 T 05-07-2017 K08M4_RS07970 fb75ce96280d0f24d881b731fa27c131 231 Pfam PF06508 Queuosine biosynthesis protein QueC 3 212 2.5E-84 T 05-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 K08M4_RS07970 fb75ce96280d0f24d881b731fa27c131 231 PIRSF PIRSF006293 1 222 1.3E-81 T 05-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 K08M4_RS07970 fb75ce96280d0f24d881b731fa27c131 231 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 205 2.4E-83 T 05-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 K08M4_RS07970 fb75ce96280d0f24d881b731fa27c131 231 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 218 49.646 T 05-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 K08M4_RS07970 fb75ce96280d0f24d881b731fa27c131 231 Gene3D G3DSA:3.40.50.620 1 212 9.0E-82 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS14075 c0a0ad1de6736fd846806a2e347602e8 386 Gene3D G3DSA:3.40.50.1970 1 193 2.1E-53 T 05-07-2017 K08M4_RS14075 c0a0ad1de6736fd846806a2e347602e8 386 Gene3D G3DSA:1.20.1090.10 194 360 4.0E-48 T 05-07-2017 K08M4_RS14075 c0a0ad1de6736fd846806a2e347602e8 386 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 182 210 - T 05-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 K08M4_RS14075 c0a0ad1de6736fd846806a2e347602e8 386 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 361 6.2E-106 T 05-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 K08M4_RS14075 c0a0ad1de6736fd846806a2e347602e8 386 SUPERFAMILY SSF56796 3 361 2.36E-100 T 05-07-2017 K08M4_RS04630 78c9da2f5f9ead41698ca7a9bd8b1c6f 82 Pfam PF03692 Putative zinc- or iron-chelating domain 2 60 3.0E-6 T 05-07-2017 IPR005358 Putative zinc- or iron-chelating domain containing protein K08M4_RS13380 cce42a2daa7ed082be048dfa0275f1fa 240 TIGRFAM TIGR04219 OMP_w_GlyGly: outer membrane protein 8 240 1.2E-45 T 05-07-2017 IPR026387 Outer membrane protein K08M4_RS15685 7d5f5ffa01b06829eef57bb61c21e300 293 Gene3D G3DSA:3.20.20.150 13 269 2.5E-46 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain K08M4_RS15685 7d5f5ffa01b06829eef57bb61c21e300 293 TIGRFAM TIGR00542 hxl6Piso_put: putative hexulose-6-phosphate isomerase 7 273 2.5E-101 T 05-07-2017 IPR004560 L-ribulose-5-phosphate 3-epimerase GO:0005975|GO:0016861 KEGG: 00053+5.1.3.22|MetaCyc: PWY-6961 K08M4_RS15685 7d5f5ffa01b06829eef57bb61c21e300 293 SUPERFAMILY SSF51658 7 274 7.73E-52 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain K08M4_RS15685 7d5f5ffa01b06829eef57bb61c21e300 293 Pfam PF01261 Xylose isomerase-like TIM barrel 27 238 1.6E-34 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain K08M4_RS16365 4032a06da5b5dd0352c2e402e40bfa62 469 SMART SM00729 62 285 4.8E-36 T 05-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 K08M4_RS16365 4032a06da5b5dd0352c2e402e40bfa62 469 TIGRFAM TIGR04107 rSAM_HutW: putative heme utilization radical SAM enzyme HutW 23 442 4.2E-181 T 05-07-2017 IPR026332 Putative heme utilization radical SAM enzyme HutW K08M4_RS16365 4032a06da5b5dd0352c2e402e40bfa62 469 SUPERFAMILY SSF102114 59 439 6.15E-82 T 05-07-2017 K08M4_RS16365 4032a06da5b5dd0352c2e402e40bfa62 469 Pfam PF04055 Radical SAM superfamily 67 238 3.2E-13 T 05-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 K08M4_RS16365 4032a06da5b5dd0352c2e402e40bfa62 469 Gene3D G3DSA:3.80.30.20 63 264 9.4E-24 T 05-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe K08M4_RS20535 41e1550681fabd7aaaddd7f9a0c70798 245 Pfam PF01925 Sulfite exporter TauE/SafE 14 237 7.9E-23 T 05-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 K08M4_RS20435 458cebebc693422f0e3a6582a57f7b16 195 Pfam PF06042 Nucleotidyltransferase 25 181 6.8E-62 T 05-07-2017 IPR009267 Putative nucleotidyltransferase K08M4_RS19245 6ee0ab19e2cada6f642426b45af2d2b1 180 Pfam PF14316 Domain of unknown function (DUF4381) 15 164 7.4E-25 T 05-07-2017 IPR025489 Protein of unknown function (DUF4381 K08M4_RS10630 c732679c6c16963bc09d527ea0d37738 177 TIGRFAM TIGR01752 flav_long: flavodoxin 4 170 2.7E-70 T 05-07-2017 IPR010086 Flavodoxin, long chain GO:0010181 K08M4_RS10630 c732679c6c16963bc09d527ea0d37738 177 Gene3D G3DSA:3.40.50.360 1 171 2.3E-61 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS10630 c732679c6c16963bc09d527ea0d37738 177 PIRSF PIRSF038996 1 174 7.4E-66 T 05-07-2017 IPR010086 Flavodoxin, long chain GO:0010181 K08M4_RS10630 c732679c6c16963bc09d527ea0d37738 177 SUPERFAMILY SSF52218 4 173 6.83E-49 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS10630 c732679c6c16963bc09d527ea0d37738 177 Pfam PF00258 Flavodoxin 6 162 4.9E-32 T 05-07-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 K08M4_RS10630 c732679c6c16963bc09d527ea0d37738 177 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 05-07-2017 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 K08M4_RS18820 3b166b11ad2ae9115b1ff65106382465 164 Pfam PF06496 Protein of unknown function (DUF1097) 9 141 4.2E-36 T 05-07-2017 IPR009476 Protein of unknown function DUF1097 K08M4_RS15960 af85372bb817b20a21deb7f0376a8fe8 313 Pfam PF00561 alpha/beta hydrolase fold 37 138 8.3E-15 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS15960 af85372bb817b20a21deb7f0376a8fe8 313 SUPERFAMILY SSF53474 33 309 1.99E-47 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS15960 af85372bb817b20a21deb7f0376a8fe8 313 Gene3D G3DSA:3.40.50.1820 29 311 9.0E-62 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS00935 ea8b53dfe3fd4f9af67a8a0e18fe4d3d 649 Gene3D G3DSA:2.30.38.10 439 515 1.3E-6 T 05-07-2017 K08M4_RS00935 ea8b53dfe3fd4f9af67a8a0e18fe4d3d 649 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 2 645 52.188 T 05-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 K08M4_RS00935 ea8b53dfe3fd4f9af67a8a0e18fe4d3d 649 Pfam PF13193 AMP-binding enzyme C-terminal domain 531 609 1.4E-23 T 05-07-2017 IPR025110 AMP-binding enzyme C-terminal domain K08M4_RS00935 ea8b53dfe3fd4f9af67a8a0e18fe4d3d 649 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 24 81 5.6E-21 T 05-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 K08M4_RS00935 ea8b53dfe3fd4f9af67a8a0e18fe4d3d 649 Gene3D G3DSA:3.30.300.30 518 637 2.6E-26 T 05-07-2017 K08M4_RS00935 ea8b53dfe3fd4f9af67a8a0e18fe4d3d 649 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 20 643 0.0 T 05-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 K08M4_RS00935 ea8b53dfe3fd4f9af67a8a0e18fe4d3d 649 Gene3D G3DSA:3.40.50.980 80 266 8.3E-44 T 05-07-2017 K08M4_RS00935 ea8b53dfe3fd4f9af67a8a0e18fe4d3d 649 Gene3D G3DSA:3.40.50.980 267 427 2.3E-27 T 05-07-2017 K08M4_RS00935 ea8b53dfe3fd4f9af67a8a0e18fe4d3d 649 SUPERFAMILY SSF56801 9 643 3.66E-180 T 05-07-2017 K08M4_RS00935 ea8b53dfe3fd4f9af67a8a0e18fe4d3d 649 ProSitePatterns PS00455 Putative AMP-binding domain signature. 261 272 - T 05-07-2017 IPR020845 AMP-binding, conserved site K08M4_RS00935 ea8b53dfe3fd4f9af67a8a0e18fe4d3d 649 Pfam PF00501 AMP-binding enzyme 84 522 9.3E-86 T 05-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 K08M4_RS15040 b98f07255ecc9163f78cbf72fd24527c 196 Pfam PF13505 Outer membrane protein beta-barrel domain 14 196 3.1E-25 T 05-07-2017 IPR027385 Outer membrane protein beta-barrel K08M4_RS15040 b98f07255ecc9163f78cbf72fd24527c 196 Gene3D G3DSA:2.40.160.20 18 196 1.3E-35 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS15040 b98f07255ecc9163f78cbf72fd24527c 196 SUPERFAMILY SSF56925 30 196 4.71E-25 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS21550 4d872d3b166fcccfc17950bffd2a91bd 215 Pfam PF08281 Sigma-70, region 4 155 205 4.3E-12 T 05-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS21550 4d872d3b166fcccfc17950bffd2a91bd 215 SUPERFAMILY SSF88659 148 210 1.87E-12 T 05-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS21550 4d872d3b166fcccfc17950bffd2a91bd 215 Gene3D G3DSA:1.10.1740.10 42 118 7.6E-17 T 05-07-2017 K08M4_RS21550 4d872d3b166fcccfc17950bffd2a91bd 215 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 47 208 6.2E-23 T 05-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS21550 4d872d3b166fcccfc17950bffd2a91bd 215 Pfam PF04542 Sigma-70 region 2 54 117 3.4E-13 T 05-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS21550 4d872d3b166fcccfc17950bffd2a91bd 215 Gene3D G3DSA:1.10.10.10 148 211 2.0E-16 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21550 4d872d3b166fcccfc17950bffd2a91bd 215 SUPERFAMILY SSF88946 36 133 2.62E-18 T 05-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 K08M4_RS02435 572f3b26e60e37e4caae77e6b391c3ac 320 PIRSF PIRSF005427 1 318 2.4E-87 T 05-07-2017 IPR005588 MucB/RseB K08M4_RS02435 572f3b26e60e37e4caae77e6b391c3ac 320 Gene3D G3DSA:2.50.20.10 121 188 5.6E-10 T 05-07-2017 K08M4_RS02435 572f3b26e60e37e4caae77e6b391c3ac 320 Pfam PF03888 MucB/RseB N-terminal domain 25 196 1.1E-60 T 05-07-2017 IPR033434 MucB/RseB, N-terminal K08M4_RS02435 572f3b26e60e37e4caae77e6b391c3ac 320 Pfam PF17188 MucB/RseB C-terminal domain 218 311 1.4E-28 T 05-07-2017 IPR033436 MucB/RseB, C-terminal K08M4_RS19360 3e0d2bd14b2bae2a6876e4b101aa5979 430 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 81 92 7.4E-8 T 05-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 K08M4_RS19360 3e0d2bd14b2bae2a6876e4b101aa5979 430 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 51 59 7.4E-8 T 05-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 K08M4_RS19360 3e0d2bd14b2bae2a6876e4b101aa5979 430 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 138 152 7.4E-8 T 05-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 K08M4_RS19360 3e0d2bd14b2bae2a6876e4b101aa5979 430 Pfam PF00561 alpha/beta hydrolase fold 49 260 6.6E-22 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS19360 3e0d2bd14b2bae2a6876e4b101aa5979 430 SUPERFAMILY SSF53474 45 168 2.09E-32 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS19360 3e0d2bd14b2bae2a6876e4b101aa5979 430 SUPERFAMILY SSF53474 261 417 2.09E-32 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS19360 3e0d2bd14b2bae2a6876e4b101aa5979 430 Gene3D G3DSA:3.40.50.1820 13 241 5.5E-56 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS19360 3e0d2bd14b2bae2a6876e4b101aa5979 430 Gene3D G3DSA:3.40.50.1820 308 420 5.5E-56 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS19290 6cd4af009466f07f049e7e5dfa2a344b 35 Gene3D G3DSA:3.40.630.30 1 34 3.9E-9 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS19290 6cd4af009466f07f049e7e5dfa2a344b 35 SUPERFAMILY SSF55729 2 34 1.39E-6 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS15825 288f8bfdb6c1c80a7e776c3de908893e 146 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 05-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site K08M4_RS15825 288f8bfdb6c1c80a7e776c3de908893e 146 Gene3D G3DSA:3.30.70.920 55 138 3.2E-22 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS15825 288f8bfdb6c1c80a7e776c3de908893e 146 Gene3D G3DSA:1.10.10.10 2 53 3.0E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15825 288f8bfdb6c1c80a7e776c3de908893e 146 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 2.8E-16 T 05-07-2017 K08M4_RS15825 288f8bfdb6c1c80a7e776c3de908893e 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 4.1E-16 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS15825 288f8bfdb6c1c80a7e776c3de908893e 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 4.1E-16 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS15825 288f8bfdb6c1c80a7e776c3de908893e 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 4.1E-16 T 05-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 K08M4_RS15825 288f8bfdb6c1c80a7e776c3de908893e 146 SMART SM00344 1 110 1.8E-34 T 05-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 K08M4_RS15825 288f8bfdb6c1c80a7e776c3de908893e 146 Pfam PF01037 Lrp/AsnC ligand binding domain 67 141 2.7E-16 T 05-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain K08M4_RS15825 288f8bfdb6c1c80a7e776c3de908893e 146 SUPERFAMILY SSF54909 63 145 5.5E-16 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel K08M4_RS15825 288f8bfdb6c1c80a7e776c3de908893e 146 SUPERFAMILY SSF46785 1 60 9.98E-15 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS05435 c2e9d96f9c97675084b1f8215f8c4a58 196 PIRSF PIRSF028788 1 196 1.3E-49 T 05-07-2017 IPR026256 Transcriptional regulator, TfoX/Sxy-type K08M4_RS05435 c2e9d96f9c97675084b1f8215f8c4a58 196 Pfam PF04993 TfoX N-terminal domain 12 102 1.6E-29 T 05-07-2017 IPR007076 TfoX, N-terminal K08M4_RS05435 c2e9d96f9c97675084b1f8215f8c4a58 196 Pfam PF04994 TfoX C-terminal domain 115 194 3.3E-31 T 05-07-2017 IPR007077 TfoX, C-terminal K08M4_RS05435 c2e9d96f9c97675084b1f8215f8c4a58 196 Gene3D G3DSA:3.30.1460.30 3 104 1.2E-35 T 05-07-2017 IPR007076 TfoX, N-terminal K08M4_RS05435 c2e9d96f9c97675084b1f8215f8c4a58 196 Gene3D G3DSA:1.10.150.20 114 195 1.9E-29 T 05-07-2017 K08M4_RS05435 c2e9d96f9c97675084b1f8215f8c4a58 196 SUPERFAMILY SSF159894 5 104 5.49E-31 T 05-07-2017 K08M4_RS07255 aec4f49182cd3c74c4985ec08cb81e3f 182 SUPERFAMILY SSF55729 1 171 1.26E-35 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS07255 aec4f49182cd3c74c4985ec08cb81e3f 182 Gene3D G3DSA:3.40.630.30 2 176 5.8E-38 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS07255 aec4f49182cd3c74c4985ec08cb81e3f 182 Pfam PF13302 Acetyltransferase (GNAT) domain 8 147 8.9E-18 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS08830 4d0d7ba632603a110c2832c1cf166671 96 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 4 81 1.5E-10 T 05-07-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family K08M4_RS08830 4d0d7ba632603a110c2832c1cf166671 96 SUPERFAMILY SSF143011 1 82 2.88E-23 T 05-07-2017 K08M4_RS08830 4d0d7ba632603a110c2832c1cf166671 96 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 83 4.0E-13 T 05-07-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family K08M4_RS08785 acf4b5e15941e1ec646dbdb18db5804f 92 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 1 92 3.0E-42 T 05-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 K08M4_RS08785 acf4b5e15941e1ec646dbdb18db5804f 92 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 1 92 25.734 T 05-07-2017 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 K08M4_RS08785 acf4b5e15941e1ec646dbdb18db5804f 92 Pfam PF01386 Ribosomal L25p family 4 89 1.9E-22 T 05-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 K08M4_RS08785 acf4b5e15941e1ec646dbdb18db5804f 92 Gene3D G3DSA:2.40.240.10 1 92 5.3E-31 T 05-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 K08M4_RS08785 acf4b5e15941e1ec646dbdb18db5804f 92 SUPERFAMILY SSF50715 1 92 2.96E-27 T 05-07-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 K08M4_RS20465 548fd9ba180ce384dad478c1053b454e 344 Gene3D G3DSA:3.40.50.1820 38 180 5.9E-51 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS20465 548fd9ba180ce384dad478c1053b454e 344 Gene3D G3DSA:3.40.50.1820 223 342 5.9E-51 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS20465 548fd9ba180ce384dad478c1053b454e 344 PIRSF PIRSF031982 2 344 1.9E-85 T 05-07-2017 IPR016986 Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL K08M4_RS20465 548fd9ba180ce384dad478c1053b454e 344 Pfam PF12740 Chlorophyllase enzyme 79 184 1.2E-6 T 05-07-2017 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 K08M4_RS20465 548fd9ba180ce384dad478c1053b454e 344 SUPERFAMILY SSF53474 223 308 9.67E-31 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS20465 548fd9ba180ce384dad478c1053b454e 344 SUPERFAMILY SSF53474 59 180 9.67E-31 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS12295 8b24f7b5d25df80e3ca9ed43e5422a74 193 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 22 177 37.497 T 05-07-2017 IPR022927 RNA pyrophosphohydrolase RppH K08M4_RS12295 8b24f7b5d25df80e3ca9ed43e5422a74 193 Gene3D G3DSA:3.90.79.10 26 172 2.8E-32 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS12295 8b24f7b5d25df80e3ca9ed43e5422a74 193 SUPERFAMILY SSF55811 23 173 1.49E-32 T 05-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 K08M4_RS12295 8b24f7b5d25df80e3ca9ed43e5422a74 193 ProSitePatterns PS00893 Nudix box signature. 59 80 - T 05-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 K08M4_RS12295 8b24f7b5d25df80e3ca9ed43e5422a74 193 Pfam PF00293 NUDIX domain 28 166 8.5E-27 T 05-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 K08M4_RS12295 8b24f7b5d25df80e3ca9ed43e5422a74 193 PRINTS PR00502 NUDIX hydrolase family signature 68 83 3.3E-8 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 K08M4_RS12295 8b24f7b5d25df80e3ca9ed43e5422a74 193 PRINTS PR00502 NUDIX hydrolase family signature 54 68 3.3E-8 T 05-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 K08M4_RS11050 3098f4e24c6d5f8274f182e5f9c072aa 420 Pfam PF09839 Uncharacterized protein conserved in bacteria (DUF2066) 18 250 3.4E-68 T 05-07-2017 IPR018642 Protein of unknown function DUF2066 K08M4_RS11705 488fbcc6ac42d5577c98e25aef62f910 193 Hamap MF_01151 Protein GrpE [grpE]. 2 193 22.186 T 05-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 K08M4_RS11705 488fbcc6ac42d5577c98e25aef62f910 193 Gene3D G3DSA:2.30.22.10 137 193 5.6E-27 T 05-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 K08M4_RS11705 488fbcc6ac42d5577c98e25aef62f910 193 PRINTS PR00773 GrpE protein signature 145 160 8.2E-28 T 05-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 K08M4_RS11705 488fbcc6ac42d5577c98e25aef62f910 193 PRINTS PR00773 GrpE protein signature 172 191 8.2E-28 T 05-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 K08M4_RS11705 488fbcc6ac42d5577c98e25aef62f910 193 PRINTS PR00773 GrpE protein signature 62 78 8.2E-28 T 05-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 K08M4_RS11705 488fbcc6ac42d5577c98e25aef62f910 193 PRINTS PR00773 GrpE protein signature 90 105 8.2E-28 T 05-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 K08M4_RS11705 488fbcc6ac42d5577c98e25aef62f910 193 Pfam PF01025 GrpE 29 193 4.0E-54 T 05-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 K08M4_RS11705 488fbcc6ac42d5577c98e25aef62f910 193 SUPERFAMILY SSF58014 39 137 3.66E-29 T 05-07-2017 K08M4_RS11705 488fbcc6ac42d5577c98e25aef62f910 193 ProSitePatterns PS01071 grpE protein signature. 148 191 - T 05-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 K08M4_RS11705 488fbcc6ac42d5577c98e25aef62f910 193 Gene3D G3DSA:3.90.20.20 37 136 9.3E-33 T 05-07-2017 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 K08M4_RS11705 488fbcc6ac42d5577c98e25aef62f910 193 SUPERFAMILY SSF51064 138 193 8.76E-20 T 05-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 K08M4_RS18560 afa82ae35bee7296f25ef08db611ba14 322 Gene3D G3DSA:1.10.150.130 37 118 2.9E-14 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal K08M4_RS18560 afa82ae35bee7296f25ef08db611ba14 322 Gene3D G3DSA:1.10.443.10 129 303 1.1E-33 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS18560 afa82ae35bee7296f25ef08db611ba14 322 SUPERFAMILY SSF47823 29 122 2.04E-19 T 05-07-2017 IPR010998 Integrase, Lambda-type, N-terminal K08M4_RS18560 afa82ae35bee7296f25ef08db611ba14 322 Pfam PF00589 Phage integrase family 141 302 3.5E-10 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS18560 afa82ae35bee7296f25ef08db611ba14 322 SUPERFAMILY SSF56349 139 307 5.3E-25 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS03940 3a34b6ae67a9bc41d3fdaee337c23573 608 Gene3D G3DSA:3.90.550.10 22 138 3.4E-10 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS03940 3a34b6ae67a9bc41d3fdaee337c23573 608 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 381 595 3.0E-12 T 05-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 K08M4_RS03940 3a34b6ae67a9bc41d3fdaee337c23573 608 Pfam PF00535 Glycosyl transferase family 2 21 141 8.3E-17 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 K08M4_RS03940 3a34b6ae67a9bc41d3fdaee337c23573 608 SUPERFAMILY SSF53448 20 250 3.49E-31 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS16080 8663db7c6275e61383d6bfad8617b386 297 SUPERFAMILY SSF103481 188 285 5.95E-15 T 05-07-2017 K08M4_RS16080 8663db7c6275e61383d6bfad8617b386 297 SUPERFAMILY SSF103481 35 138 3.27E-12 T 05-07-2017 K08M4_RS16080 8663db7c6275e61383d6bfad8617b386 297 Pfam PF00892 EamA-like transporter family 151 280 9.2E-19 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS16080 8663db7c6275e61383d6bfad8617b386 297 Pfam PF00892 EamA-like transporter family 3 135 6.1E-20 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS15905 0b13c5a9e03058fd3b381f45573520dd 376 Gene3D G3DSA:2.40.50.100 217 239 2.4E-10 T 05-07-2017 K08M4_RS15905 0b13c5a9e03058fd3b381f45573520dd 376 Gene3D G3DSA:2.40.50.100 66 96 2.4E-10 T 05-07-2017 K08M4_RS15905 0b13c5a9e03058fd3b381f45573520dd 376 Pfam PF13533 Biotin-lipoyl like 64 111 4.5E-7 T 05-07-2017 K08M4_RS15905 0b13c5a9e03058fd3b381f45573520dd 376 SUPERFAMILY SSF111369 140 188 8.24E-9 T 05-07-2017 K08M4_RS15905 0b13c5a9e03058fd3b381f45573520dd 376 SUPERFAMILY SSF111369 61 111 8.24E-9 T 05-07-2017 K08M4_RS06645 b259a4f6ada956c7531c3b99b2a4aeb1 188 Pfam PF07209 Protein of unknown function (DUF1415) 12 179 1.3E-65 T 05-07-2017 IPR009858 Protein of unknown function DUF1415 K08M4_RS19465 3462f5db541834cd9b1c7e23de7dff90 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.0E-19 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS19465 3462f5db541834cd9b1c7e23de7dff90 333 Gene3D G3DSA:3.40.50.2300 175 311 3.6E-51 T 05-07-2017 K08M4_RS19465 3462f5db541834cd9b1c7e23de7dff90 333 SUPERFAMILY SSF53822 60 331 1.99E-89 T 05-07-2017 IPR028082 Periplasmic binding protein-like I K08M4_RS19465 3462f5db541834cd9b1c7e23de7dff90 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 5.5E-5 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS19465 3462f5db541834cd9b1c7e23de7dff90 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 5.5E-5 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS19465 3462f5db541834cd9b1c7e23de7dff90 333 SMART SM00354 1 71 2.7E-35 T 05-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 K08M4_RS19465 3462f5db541834cd9b1c7e23de7dff90 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 05-07-2017 K08M4_RS19465 3462f5db541834cd9b1c7e23de7dff90 333 Gene3D G3DSA:1.10.260.40 2 53 3.3E-24 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS19465 3462f5db541834cd9b1c7e23de7dff90 333 Pfam PF13377 Periplasmic binding protein-like domain 170 330 2.4E-41 T 05-07-2017 K08M4_RS19465 3462f5db541834cd9b1c7e23de7dff90 333 Gene3D G3DSA:3.40.50.2300 54 174 3.3E-45 T 05-07-2017 K08M4_RS19465 3462f5db541834cd9b1c7e23de7dff90 333 SUPERFAMILY SSF47413 1 59 4.5E-17 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS03895 59816e9e800058329991f52b0964fc01 407 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 05-07-2017 IPR018201 Beta-ketoacyl synthase, active site K08M4_RS03895 59816e9e800058329991f52b0964fc01 407 Gene3D G3DSA:3.40.47.10 2 260 9.0E-58 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS03895 59816e9e800058329991f52b0964fc01 407 SUPERFAMILY SSF53901 216 406 1.98E-58 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS03895 59816e9e800058329991f52b0964fc01 407 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 363 2.1E-28 T 05-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal K08M4_RS03895 59816e9e800058329991f52b0964fc01 407 SUPERFAMILY SSF53901 3 252 7.69E-56 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS03895 59816e9e800058329991f52b0964fc01 407 Gene3D G3DSA:3.40.47.10 264 406 1.5E-47 T 05-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 K08M4_RS03895 59816e9e800058329991f52b0964fc01 407 SMART SM00825 Beta-ketoacyl synthase 5 407 4.8E-10 T 05-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain K08M4_RS03895 59816e9e800058329991f52b0964fc01 407 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 247 2.8E-42 T 05-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal K08M4_RS03365 152c3f5d7b8523e900b5a18abb2f9542 421 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 16 59 4.3E-10 T 05-07-2017 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal K08M4_RS03365 152c3f5d7b8523e900b5a18abb2f9542 421 Gene3D G3DSA:2.40.170.20 239 334 8.8E-4 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS03365 152c3f5d7b8523e900b5a18abb2f9542 421 Gene3D G3DSA:2.40.170.20 98 145 8.8E-4 T 05-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 K08M4_RS08425 ba4750702b7ffe0a7bcc137258d73c53 946 Gene3D G3DSA:3.30.420.40 6 227 8.1E-35 T 05-07-2017 K08M4_RS08425 ba4750702b7ffe0a7bcc137258d73c53 946 Pfam PF12531 DNA-K related protein 696 943 9.4E-102 T 05-07-2017 IPR021030 Protein of unknown function DUF3731 K08M4_RS08425 ba4750702b7ffe0a7bcc137258d73c53 946 Pfam PF00012 Hsp70 protein 90 317 2.8E-15 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS08425 ba4750702b7ffe0a7bcc137258d73c53 946 SUPERFAMILY SSF53067 413 466 3.56E-21 T 05-07-2017 K08M4_RS08425 ba4750702b7ffe0a7bcc137258d73c53 946 SUPERFAMILY SSF53067 223 374 3.56E-21 T 05-07-2017 K08M4_RS08425 ba4750702b7ffe0a7bcc137258d73c53 946 Gene3D G3DSA:3.30.420.40 228 342 3.3E-16 T 05-07-2017 K08M4_RS08425 ba4750702b7ffe0a7bcc137258d73c53 946 SUPERFAMILY SSF53067 6 209 2.75E-29 T 05-07-2017 K08M4_RS08425 ba4750702b7ffe0a7bcc137258d73c53 946 PRINTS PR00301 70kDa heat shock protein signature 232 242 5.3E-9 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS08425 ba4750702b7ffe0a7bcc137258d73c53 946 PRINTS PR00301 70kDa heat shock protein signature 165 185 5.3E-9 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS08425 ba4750702b7ffe0a7bcc137258d73c53 946 PRINTS PR00301 70kDa heat shock protein signature 408 428 5.3E-9 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS08425 ba4750702b7ffe0a7bcc137258d73c53 946 PRINTS PR00301 70kDa heat shock protein signature 6 19 5.3E-9 T 05-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 K08M4_RS11400 a399c2109a54f334c0a9265f8eb568c1 181 Hamap MF_01104 Protein Syd [syd]. 3 181 36.316 T 05-07-2017 IPR009948 Syd GO:0009898 K08M4_RS11400 a399c2109a54f334c0a9265f8eb568c1 181 Pfam PF07348 Syd protein (SUKH-2) 7 179 1.8E-69 T 05-07-2017 IPR009948 Syd GO:0009898 K08M4_RS18875 5e9de62c0b9314fc4acac0d6235994e7 248 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 6.7E-12 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS18875 5e9de62c0b9314fc4acac0d6235994e7 248 SUPERFAMILY SSF46689 10 89 3.33E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS18875 5e9de62c0b9314fc4acac0d6235994e7 248 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 3.1E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS18875 5e9de62c0b9314fc4acac0d6235994e7 248 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 3.1E-7 T 05-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 K08M4_RS18875 5e9de62c0b9314fc4acac0d6235994e7 248 Gene3D G3DSA:1.10.357.10 4 207 3.2E-22 T 05-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 K08M4_RS12685 11a5469edc61b6eba13f741da9e80c46 151 PIRSF PIRSF006318 1 140 2.4E-49 T 05-07-2017 IPR009386 Protein of unknown function DUF1043 K08M4_RS12685 11a5469edc61b6eba13f741da9e80c46 151 Pfam PF06295 Protein of unknown function (DUF1043) 6 133 5.5E-45 T 05-07-2017 IPR009386 Protein of unknown function DUF1043 K08M4_RS15670 92d38945e740662c2ef38b9a0a362f4e 230 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 196 2.2E-43 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal K08M4_RS15670 92d38945e740662c2ef38b9a0a362f4e 230 Gene3D G3DSA:3.40.225.10 4 229 2.6E-68 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal K08M4_RS15670 92d38945e740662c2ef38b9a0a362f4e 230 SUPERFAMILY SSF53639 3 220 4.51E-64 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal K08M4_RS15670 92d38945e740662c2ef38b9a0a362f4e 230 SMART SM01007 7 197 5.0E-63 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal K08M4_RS19025 15d90c70f5beb1bad3ef3b79f84760c4 350 Pfam PF04986 Putative transposase 138 298 7.0E-37 T 05-07-2017 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 K08M4_RS19025 15d90c70f5beb1bad3ef3b79f84760c4 350 Pfam PF14319 Transposase zinc-binding domain 7 114 5.3E-31 T 05-07-2017 IPR026889 Transposase zinc-binding domain K08M4_RS04115 f070686b34c0d9f5a91db1a161616a19 141 Gene3D G3DSA:3.30.160.170 47 129 2.2E-23 T 05-07-2017 IPR005186 FlaG protein K08M4_RS04115 f070686b34c0d9f5a91db1a161616a19 141 SUPERFAMILY SSF160214 54 130 1.96E-21 T 05-07-2017 IPR005186 FlaG protein K08M4_RS04115 f070686b34c0d9f5a91db1a161616a19 141 Pfam PF03646 FlaG protein 42 130 1.7E-22 T 05-07-2017 IPR005186 FlaG protein K08M4_RS06760 f6b3bb5d5223f97af3769b642f2da825 158 Pfam PF04002 RadC-like JAB domain 38 156 8.7E-45 T 05-07-2017 IPR025657 RadC-like JAB domain K08M4_RS06760 f6b3bb5d5223f97af3769b642f2da825 158 SUPERFAMILY SSF102712 58 125 4.05E-6 T 05-07-2017 K08M4_RS06760 f6b3bb5d5223f97af3769b642f2da825 158 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 108 113 - T 05-07-2017 IPR020891 Uncharacterised protein family UPF0758, conserved site K08M4_RS06760 f6b3bb5d5223f97af3769b642f2da825 158 Gene3D G3DSA:3.40.140.10 37 157 8.6E-49 T 05-07-2017 K08M4_RS06760 f6b3bb5d5223f97af3769b642f2da825 158 TIGRFAM TIGR00608 radc: DNA repair protein RadC 16 158 6.7E-43 T 05-07-2017 IPR001405 RadC protein K08M4_RS01965 9a12181903eec80f09aadded8babeb28 135 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 129 7.9E-12 T 05-07-2017 IPR028973 PhnB-like K08M4_RS01965 9a12181903eec80f09aadded8babeb28 135 SUPERFAMILY SSF54593 3 133 7.16E-33 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS01965 9a12181903eec80f09aadded8babeb28 135 Gene3D G3DSA:3.10.180.10 8 132 9.7E-40 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS18710 c63b24e0f7dae737469c0cec650aa51c 386 Pfam PF01103 Surface antigen 204 276 1.2E-7 T 05-07-2017 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020 K08M4_RS18710 c63b24e0f7dae737469c0cec650aa51c 386 Gene3D G3DSA:2.40.160.10 230 378 4.0E-4 T 05-07-2017 IPR023614 Porin domain K08M4_RS18710 c63b24e0f7dae737469c0cec650aa51c 386 SUPERFAMILY SSF56935 211 371 2.66E-5 T 05-07-2017 K08M4_RS19985 cbe0450afbc25f6692df829998747677 162 Pfam PF06891 P2 phage tail completion protein R (GpR) 10 141 2.7E-16 T 05-07-2017 IPR009678 Bacteriophage tail completion protein R K08M4_RS07960 03fddead1eaaed61357d3c97dffd980b 116 Pfam PF11042 Protein of unknown function (DUF2750) 13 113 1.4E-32 T 05-07-2017 IPR021284 Protein of unknown function DUF2750 K08M4_RS21025 0fcf9233cddd038ba8490fae4a3b5936 452 SUPERFAMILY SSF53955 263 390 1.69E-29 T 05-07-2017 IPR023346 Lysozyme-like domain K08M4_RS21025 0fcf9233cddd038ba8490fae4a3b5936 452 Pfam PF00912 Transglycosylase 263 393 8.7E-31 T 05-07-2017 IPR001264 Glycosyl transferase, family 51 K08M4_RS21025 0fcf9233cddd038ba8490fae4a3b5936 452 Gene3D G3DSA:1.10.3810.10 263 391 2.5E-30 T 05-07-2017 K08M4_RS20430 91e11e503330cf1266ab27dae83671c2 95 Gene3D G3DSA:3.30.70.900 1 82 1.5E-15 T 05-07-2017 K08M4_RS20430 91e11e503330cf1266ab27dae83671c2 95 SUPERFAMILY SSF54909 3 82 1.24E-17 T 05-07-2017 IPR011008 Dimeric alpha-beta barrel K08M4_RS20430 91e11e503330cf1266ab27dae83671c2 95 Pfam PF03992 Antibiotic biosynthesis monooxygenase 10 70 1.0E-10 T 05-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain K08M4_RS02880 772f15ad0c98ef530f41bb71005faf36 161 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 134 2.8E-46 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS02880 772f15ad0c98ef530f41bb71005faf36 161 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 134 4.7E-38 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS02880 772f15ad0c98ef530f41bb71005faf36 161 SUPERFAMILY SSF55083 1 158 4.45E-54 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS02880 772f15ad0c98ef530f41bb71005faf36 161 Gene3D G3DSA:3.30.70.560 3 154 3.9E-58 T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS02880 772f15ad0c98ef530f41bb71005faf36 161 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 05-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 K08M4_RS13420 6a35698a425173213d13d1da7c070223 153 SUPERFAMILY SSF103039 1 153 2.49E-38 T 05-07-2017 IPR028976 CheC-like domain K08M4_RS13420 6a35698a425173213d13d1da7c070223 153 Pfam PF13690 Chemotaxis phosphatase CheX 42 139 7.6E-22 T 05-07-2017 IPR028051 Chemotaxis phosphatase CheX-like domain K08M4_RS13420 6a35698a425173213d13d1da7c070223 153 Gene3D G3DSA:3.40.1550.10 1 153 4.6E-44 T 05-07-2017 IPR028976 CheC-like domain K08M4_RS09815 42b98bffb50e058e74d1bd5ac8e7b1a6 170 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 23 164 7.6E-46 T 05-07-2017 IPR018639 Domain of unknown function DUF2062 K08M4_RS12775 dcf8636dd396b560f3b14c62ab04f2fb 313 Pfam PF16537 Type II secretion system protein B 248 307 4.1E-23 T 05-07-2017 IPR032389 Type II secretion system protein B K08M4_RS00055 8e5802e5f74b3efa325db9150d99862a 83 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 12 36 - T 05-07-2017 IPR001455 TusA-like domain K08M4_RS00055 8e5802e5f74b3efa325db9150d99862a 83 SUPERFAMILY SSF64307 9 80 3.92E-25 T 05-07-2017 IPR001455 TusA-like domain K08M4_RS00055 8e5802e5f74b3efa325db9150d99862a 83 Gene3D G3DSA:3.30.110.40 8 80 2.1E-28 T 05-07-2017 IPR001455 TusA-like domain K08M4_RS00055 8e5802e5f74b3efa325db9150d99862a 83 Hamap MF_00413 Sulfurtransferase TusA [tusA]. 3 81 28.177 T 05-07-2017 IPR022931 Sulphurtransferase TusA GO:0016783 K08M4_RS00055 8e5802e5f74b3efa325db9150d99862a 83 Pfam PF01206 Sulfurtransferase TusA 10 79 3.4E-23 T 05-07-2017 IPR001455 TusA-like domain K08M4_RS07410 2392329c44a56fc51e19bcfbc6c2d6ca 203 SUPERFAMILY SSF63380 1 93 5.87E-27 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 K08M4_RS07410 2392329c44a56fc51e19bcfbc6c2d6ca 203 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 202 3.5E-78 T 05-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS07410 2392329c44a56fc51e19bcfbc6c2d6ca 203 SUPERFAMILY SSF63380 93 199 2.98E-30 T 05-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 K08M4_RS07410 2392329c44a56fc51e19bcfbc6c2d6ca 203 Pfam PF00677 Lumazine binding domain 3 87 2.6E-20 T 05-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS07410 2392329c44a56fc51e19bcfbc6c2d6ca 203 Pfam PF00677 Lumazine binding domain 100 184 1.2E-17 T 05-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS07410 2392329c44a56fc51e19bcfbc6c2d6ca 203 PIRSF PIRSF000498 1 203 5.9E-68 T 05-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 K08M4_RS07410 2392329c44a56fc51e19bcfbc6c2d6ca 203 Gene3D G3DSA:2.40.30.20 5 104 4.2E-32 T 05-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 K08M4_RS07410 2392329c44a56fc51e19bcfbc6c2d6ca 203 Gene3D G3DSA:2.40.30.20 105 199 1.0E-26 T 05-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 K08M4_RS14740 19f6b4fa94739bf44a7456d6b68f70e8 89 SUPERFAMILY SSF160272 1 86 6.15E-30 T 05-07-2017 IPR009962 Protein of unknown function DUF1488 K08M4_RS14740 19f6b4fa94739bf44a7456d6b68f70e8 89 Gene3D G3DSA:3.30.160.140 1 87 1.2E-34 T 05-07-2017 IPR009962 Protein of unknown function DUF1488 K08M4_RS14740 19f6b4fa94739bf44a7456d6b68f70e8 89 Pfam PF07369 Protein of unknown function (DUF1488) 5 85 1.8E-25 T 05-07-2017 IPR009962 Protein of unknown function DUF1488 K08M4_RS05010 5f9a34fa0b80b206d099057c6e75f376 318 Gene3D G3DSA:3.20.20.70 2 243 4.8E-59 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS05010 5f9a34fa0b80b206d099057c6e75f376 318 SUPERFAMILY SSF51395 1 312 1.14E-70 T 05-07-2017 K08M4_RS05010 5f9a34fa0b80b206d099057c6e75f376 318 Hamap MF_02043 tRNA-dihydrouridine(16) synthase [dusC]. 8 310 52.139 T 05-07-2017 IPR032886 tRNA-dihydrouridine(16) synthase GO:0002943|GO:0017150 K08M4_RS05010 5f9a34fa0b80b206d099057c6e75f376 318 PIRSF PIRSF006621 1 317 4.9E-75 T 05-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 K08M4_RS05010 5f9a34fa0b80b206d099057c6e75f376 318 Pfam PF01207 Dihydrouridine synthase (Dus) 5 290 4.7E-73 T 05-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 K08M4_RS05010 5f9a34fa0b80b206d099057c6e75f376 318 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 92 110 - T 05-07-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 K08M4_RS10900 59d4a3a7732f989cc8f1e829e6388369 322 TIGRFAM TIGR01136 cysKM: cysteine synthase 10 311 1.3E-133 T 05-07-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 K08M4_RS10900 59d4a3a7732f989cc8f1e829e6388369 322 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 299 1.8E-68 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme K08M4_RS10900 59d4a3a7732f989cc8f1e829e6388369 322 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 31 49 - T 05-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 K08M4_RS10900 59d4a3a7732f989cc8f1e829e6388369 322 Gene3D G3DSA:3.40.50.1100 36 132 2.2E-37 T 05-07-2017 K08M4_RS10900 59d4a3a7732f989cc8f1e829e6388369 322 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 311 1.7E-140 T 05-07-2017 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 K08M4_RS10900 59d4a3a7732f989cc8f1e829e6388369 322 Gene3D G3DSA:3.40.50.1100 133 312 3.1E-73 T 05-07-2017 K08M4_RS10900 59d4a3a7732f989cc8f1e829e6388369 322 SUPERFAMILY SSF53686 3 313 4.06E-95 T 05-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme K08M4_RS10725 b4a41b68d9bd376447780127d9b37a82 116 SMART SM00938 6 104 3.3E-6 T 05-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 K08M4_RS10725 b4a41b68d9bd376447780127d9b37a82 116 SUPERFAMILY SSF54913 1 102 1.42E-21 T 05-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta K08M4_RS10725 b4a41b68d9bd376447780127d9b37a82 116 Gene3D G3DSA:3.30.70.120 3 103 6.9E-10 T 05-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal K08M4_RS03340 d6e77ed390440329db58a28e8ff6cd31 176 Pfam PF01478 Type IV leader peptidase family 6 111 9.3E-13 T 05-07-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 K08M4_RS16420 e3924217e832bc1f4f0d4fcd14b1a9ee 99 Gene3D G3DSA:2.60.40.10 11 81 4.6E-5 T 05-07-2017 IPR013783 Immunoglobulin-like fold K08M4_RS16420 e3924217e832bc1f4f0d4fcd14b1a9ee 99 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 22 93 3.8E-6 T 05-07-2017 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 K08M4_RS16420 e3924217e832bc1f4f0d4fcd14b1a9ee 99 SUPERFAMILY SSF81296 15 94 4.67E-14 T 05-07-2017 IPR014756 Immunoglobulin E-set K08M4_RS05620 1485be28899d4d1a0a026d4b8bcff07b 270 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS05620 1485be28899d4d1a0a026d4b8bcff07b 270 SMART SM00382 39 236 1.7E-15 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS05620 1485be28899d4d1a0a026d4b8bcff07b 270 Gene3D G3DSA:3.40.50.300 15 248 8.3E-64 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05620 1485be28899d4d1a0a026d4b8bcff07b 270 SUPERFAMILY SSF52540 15 241 7.14E-60 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS05620 1485be28899d4d1a0a026d4b8bcff07b 270 Pfam PF00005 ABC transporter 31 178 3.8E-33 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS10800 e790b1209179413e7be1b7196f5a2805 241 Pfam PF13391 HNH endonuclease 29 79 4.0E-7 T 05-07-2017 IPR003615 HNH nuclease K08M4_RS15495 958c4847cb8d63233e2936ac31be13da 75 Gene3D G3DSA:2.40.160.60 1 74 1.4E-8 T 05-07-2017 K08M4_RS21415 567c30bbadc31fbddd6bf4ccef269b9e 318 Pfam PF03547 Membrane transport protein 167 307 4.0E-12 T 05-07-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 K08M4_RS17885 75e76cb3552842540ba7511629213504 104 Pfam PF00034 Cytochrome c 34 102 4.4E-6 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS17885 75e76cb3552842540ba7511629213504 104 Gene3D G3DSA:1.10.760.10 23 103 2.1E-24 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS17885 75e76cb3552842540ba7511629213504 104 SUPERFAMILY SSF46626 33 103 3.62E-18 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS00215 b067d597b02385dd317e8e862e1b0169 255 Pfam PF09836 Putative DNA-binding domain 8 96 8.6E-22 T 05-07-2017 IPR018640 Putative DNA-binding domain, bacteria K08M4_RS01420 c4d612d9ac9fa9133cee7abfa240d2fe 241 Pfam PF13309 HTH domain 174 231 1.1E-18 T 05-07-2017 K08M4_RS01420 c4d612d9ac9fa9133cee7abfa240d2fe 241 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 30 143 2.0E-60 T 05-07-2017 IPR013559 YheO-like K08M4_RS01420 c4d612d9ac9fa9133cee7abfa240d2fe 241 Pfam PF08348 YheO-like PAS domain 31 139 8.7E-35 T 05-07-2017 IPR013559 YheO-like K08M4_RS17455 8d838d40cd6df4a5bf3bec3abab571cc 342 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 256 341 6.7E-8 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS09420 69d4736664a12c13c817567fb80f6316 76 Gene3D G3DSA:1.10.290.10 32 68 6.7E-4 T 05-07-2017 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 K08M4_RS09420 69d4736664a12c13c817567fb80f6316 76 Pfam PF06146 Phosphate-starvation-inducible E 9 66 4.4E-8 T 05-07-2017 IPR020948 Phosphate-starvation-induced PsiE-like K08M4_RS09420 69d4736664a12c13c817567fb80f6316 76 TIGRFAM TIGR02647 DNA: TIGR02647 family protein 1 75 5.6E-36 T 05-07-2017 IPR013468 Conserved hypothetical protein CHP02647 K08M4_RS06955 0ad76d633d56d4183823de8eed30ea84 519 Gene3D G3DSA:1.25.40.80 133 164 1.0E-8 T 05-07-2017 K08M4_RS06955 0ad76d633d56d4183823de8eed30ea84 519 Gene3D G3DSA:1.25.40.80 227 321 1.0E-8 T 05-07-2017 K08M4_RS06955 0ad76d633d56d4183823de8eed30ea84 519 SUPERFAMILY SSF48173 229 505 9.55E-60 T 05-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 K08M4_RS06955 0ad76d633d56d4183823de8eed30ea84 519 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 7 223 9.8E-69 T 05-07-2017 IPR007357 Deoxyribodipyrimidine photolyase-related protein K08M4_RS06955 0ad76d633d56d4183823de8eed30ea84 519 Gene3D G3DSA:1.10.579.10 322 409 7.3E-5 T 05-07-2017 K08M4_RS13810 3d496a7417aa241b090e910c102fdfd3 541 Gene3D G3DSA:3.90.550.10 3 244 4.2E-20 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS13810 3d496a7417aa241b090e910c102fdfd3 541 Gene3D G3DSA:3.90.550.10 260 499 1.1E-17 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS13810 3d496a7417aa241b090e910c102fdfd3 541 Pfam PF00483 Nucleotidyl transferase 266 447 2.4E-6 T 05-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 K08M4_RS13810 3d496a7417aa241b090e910c102fdfd3 541 Pfam PF12804 MobA-like NTP transferase domain 3 135 6.6E-8 T 05-07-2017 IPR025877 MobA-like NTP transferase K08M4_RS13810 3d496a7417aa241b090e910c102fdfd3 541 SUPERFAMILY SSF53448 3 235 1.55E-23 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS13810 3d496a7417aa241b090e910c102fdfd3 541 SUPERFAMILY SSF53448 261 503 1.26E-20 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS00425 59c1804b9e0be3c7470788ac6463dd65 276 Pfam PF01678 Diaminopimelate epimerase 154 269 7.3E-32 T 05-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 K08M4_RS00425 59c1804b9e0be3c7470788ac6463dd65 276 Pfam PF01678 Diaminopimelate epimerase 5 124 1.7E-32 T 05-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 K08M4_RS00425 59c1804b9e0be3c7470788ac6463dd65 276 SUPERFAMILY SSF54506 2 274 6.67E-52 T 05-07-2017 K08M4_RS00425 59c1804b9e0be3c7470788ac6463dd65 276 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 05-07-2017 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 K08M4_RS00425 59c1804b9e0be3c7470788ac6463dd65 276 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 274 3.6E-100 T 05-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 K08M4_RS00425 59c1804b9e0be3c7470788ac6463dd65 276 Gene3D G3DSA:3.10.310.10 4 122 5.9E-49 T 05-07-2017 K08M4_RS00425 59c1804b9e0be3c7470788ac6463dd65 276 Gene3D G3DSA:3.10.310.10 123 264 2.9E-50 T 05-07-2017 K08M4_RS00425 59c1804b9e0be3c7470788ac6463dd65 276 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 276 39.159 T 05-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 K08M4_RS09315 5b8d0fa09aac07cf5581ea3491eb751e 361 Pfam PF13533 Biotin-lipoyl like 61 103 3.4E-11 T 05-07-2017 K08M4_RS09315 5b8d0fa09aac07cf5581ea3491eb751e 361 Gene3D G3DSA:2.40.50.100 152 183 3.2E-15 T 05-07-2017 K08M4_RS09315 5b8d0fa09aac07cf5581ea3491eb751e 361 Gene3D G3DSA:2.40.50.100 59 91 3.2E-15 T 05-07-2017 K08M4_RS09315 5b8d0fa09aac07cf5581ea3491eb751e 361 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 33 353 1.3E-68 T 05-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 K08M4_RS09315 5b8d0fa09aac07cf5581ea3491eb751e 361 Pfam PF13437 HlyD family secretion protein 155 254 1.1E-5 T 05-07-2017 K08M4_RS09315 5b8d0fa09aac07cf5581ea3491eb751e 361 SUPERFAMILY SSF111369 49 264 2.48E-28 T 05-07-2017 K08M4_RS02395 7560efcdfb468d6c9da88eeabd523a72 68 Pfam PF06526 Protein of unknown function (DUF1107) 1 63 3.0E-29 T 05-07-2017 IPR009491 Protein of unknown function DUF1107 K08M4_RS02395 7560efcdfb468d6c9da88eeabd523a72 68 ProDom PD055267 YTFK Y0656 CYTOPLASMIC VP2585 VV0426 ESCHERICHIA S4534 VC2473 YPO3527 COLI 1 63 1.0E-27 T 05-07-2017 IPR009491 Protein of unknown function DUF1107 K08M4_RS02395 7560efcdfb468d6c9da88eeabd523a72 68 Gene3D G3DSA:3.30.1910.10 1 65 7.5E-31 T 05-07-2017 K08M4_RS10670 f0d87974465de1f76a5b4d0b7672ede1 554 Gene3D G3DSA:3.60.20.10 2 188 3.8E-67 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS10670 f0d87974465de1f76a5b4d0b7672ede1 554 SUPERFAMILY SSF52402 208 480 6.28E-74 T 05-07-2017 K08M4_RS10670 f0d87974465de1f76a5b4d0b7672ede1 554 Gene3D G3DSA:3.40.50.620 196 510 7.9E-116 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS10670 f0d87974465de1f76a5b4d0b7672ede1 554 Pfam PF00733 Asparagine synthase 367 511 6.0E-40 T 05-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 K08M4_RS10670 f0d87974465de1f76a5b4d0b7672ede1 554 Pfam PF00733 Asparagine synthase 211 366 1.0E-54 T 05-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 K08M4_RS10670 f0d87974465de1f76a5b4d0b7672ede1 554 Pfam PF13537 Glutamine amidotransferase domain 48 166 2.4E-40 T 05-07-2017 IPR017932 Glutamine amidotransferase type 2 domain K08M4_RS10670 f0d87974465de1f76a5b4d0b7672ede1 554 SUPERFAMILY SSF56235 1 196 7.03E-57 T 05-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal K08M4_RS10670 f0d87974465de1f76a5b4d0b7672ede1 554 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 371 3.3E-117 T 05-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 K08M4_RS00160 20903a277ce29641278bc1a6a8a0d653 649 Pfam PF13667 ThiC-associated domain 22 104 1.3E-32 T 05-07-2017 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 K08M4_RS00160 20903a277ce29641278bc1a6a8a0d653 649 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 143 594 1.3E-219 T 05-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 K08M4_RS00160 20903a277ce29641278bc1a6a8a0d653 649 Pfam PF01964 Radical SAM ThiC family 144 592 1.1E-199 T 05-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 K08M4_RS00160 20903a277ce29641278bc1a6a8a0d653 649 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 143 597 56.467 T 05-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 K08M4_RS19800 19dcca6b28a445161a13b7f576e7da8c 305 Pfam PF00892 EamA-like transporter family 164 295 8.9E-15 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS19800 19dcca6b28a445161a13b7f576e7da8c 305 Pfam PF00892 EamA-like transporter family 13 147 9.7E-9 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS19800 19dcca6b28a445161a13b7f576e7da8c 305 SUPERFAMILY SSF103481 201 301 1.57E-11 T 05-07-2017 K08M4_RS06595 022d755d2b4fc0594c1d231cde42e04c 484 Pfam PF02839 Carbohydrate binding domain 435 478 3.7E-7 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS06595 022d755d2b4fc0594c1d231cde42e04c 484 Gene3D G3DSA:2.10.10.20 436 481 6.8E-9 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS06595 022d755d2b4fc0594c1d231cde42e04c 484 SUPERFAMILY SSF51055 435 481 4.05E-7 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS06595 022d755d2b4fc0594c1d231cde42e04c 484 SUPERFAMILY SSF81296 12 199 6.72E-45 T 05-07-2017 IPR014756 Immunoglobulin E-set K08M4_RS06595 022d755d2b4fc0594c1d231cde42e04c 484 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 12 196 1.5E-33 T 05-07-2017 IPR004302 Chitin-binding protein, N-terminal K08M4_RS06595 022d755d2b4fc0594c1d231cde42e04c 484 Gene3D G3DSA:2.70.50.50 12 198 6.6E-46 T 05-07-2017 K08M4_RS06595 022d755d2b4fc0594c1d231cde42e04c 484 SMART SM00495 434 483 9.1E-4 T 05-07-2017 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 K08M4_RS20415 fcdba1895ba70abe71404db1494ca562 123 SUPERFAMILY SSF46785 1 77 9.25E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20415 fcdba1895ba70abe71404db1494ca562 123 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 73 2.5E-13 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS20415 fcdba1895ba70abe71404db1494ca562 123 SMART SM00345 14 73 2.6E-8 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS20415 fcdba1895ba70abe71404db1494ca562 123 Gene3D G3DSA:1.10.10.10 4 75 1.5E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS08620 c0220024edee09228f8da2a9bac92d24 193 Pfam PF04994 TfoX C-terminal domain 112 190 1.2E-27 T 05-07-2017 IPR007077 TfoX, C-terminal K08M4_RS08620 c0220024edee09228f8da2a9bac92d24 193 Pfam PF04993 TfoX N-terminal domain 9 98 2.4E-22 T 05-07-2017 IPR007076 TfoX, N-terminal K08M4_RS08620 c0220024edee09228f8da2a9bac92d24 193 PIRSF PIRSF028788 3 193 1.3E-34 T 05-07-2017 IPR026256 Transcriptional regulator, TfoX/Sxy-type K08M4_RS08620 c0220024edee09228f8da2a9bac92d24 193 Gene3D G3DSA:1.10.150.20 112 192 1.2E-27 T 05-07-2017 K08M4_RS08620 c0220024edee09228f8da2a9bac92d24 193 SUPERFAMILY SSF159894 4 100 3.92E-26 T 05-07-2017 K08M4_RS08620 c0220024edee09228f8da2a9bac92d24 193 Gene3D G3DSA:3.30.1460.30 3 100 1.2E-26 T 05-07-2017 IPR007076 TfoX, N-terminal K08M4_RS03015 974428b5dafc2f0cbdd1598de7935361 361 Pfam PF01594 Domain of unknown function DUF20 13 347 8.7E-53 T 05-07-2017 IPR002549 Transmembrane protein TqsA-like K08M4_RS04620 ca9d786673b402f66bf112efb824454e 199 TIGRFAM TIGR00615 recR: recombination protein RecR 3 197 2.8E-78 T 05-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 K08M4_RS04620 ca9d786673b402f66bf112efb824454e 199 SUPERFAMILY SSF111304 2 199 3.66E-72 T 05-07-2017 IPR023627 Recombination protein RecR K08M4_RS04620 ca9d786673b402f66bf112efb824454e 199 Pfam PF13662 Toprim domain 82 172 1.3E-23 T 05-07-2017 IPR006171 Toprim domain K08M4_RS04620 ca9d786673b402f66bf112efb824454e 199 Pfam PF02132 RecR protein 40 77 4.6E-15 T 05-07-2017 IPR023628 Recombination protein RecR, C4-type zinc finger K08M4_RS04620 ca9d786673b402f66bf112efb824454e 199 SMART SM00493 81 166 1.7E-17 T 05-07-2017 IPR006171 Toprim domain K08M4_RS04620 ca9d786673b402f66bf112efb824454e 199 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 05-07-2017 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 K08M4_RS04620 ca9d786673b402f66bf112efb824454e 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 199 102.295 T 05-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 K08M4_RS11510 76b7035bc2df7d554ac32699418eb38e 189 Pfam PF03923 Uncharacterized lipoprotein 28 186 2.2E-50 T 05-07-2017 IPR005619 Uncharacterised protein family, YajG K08M4_RS02705 e7235e4a2117644a89143ed0a3a868b8 317 Gene3D G3DSA:3.40.50.720 154 239 2.3E-20 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS02705 e7235e4a2117644a89143ed0a3a868b8 317 SUPERFAMILY SSF51735 122 260 1.63E-30 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS02705 e7235e4a2117644a89143ed0a3a868b8 317 SMART SM00829 12 312 6.5E-14 T 05-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 K08M4_RS02705 e7235e4a2117644a89143ed0a3a868b8 317 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 93 3.7E-7 T 05-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 K08M4_RS02705 e7235e4a2117644a89143ed0a3a868b8 317 Gene3D G3DSA:3.90.180.10 3 153 4.3E-40 T 05-07-2017 IPR011032 GroES-like K08M4_RS02705 e7235e4a2117644a89143ed0a3a868b8 317 SUPERFAMILY SSF50129 4 154 5.93E-35 T 05-07-2017 IPR011032 GroES-like K08M4_RS02705 e7235e4a2117644a89143ed0a3a868b8 317 Pfam PF13602 Zinc-binding dehydrogenase 191 312 2.4E-19 T 05-07-2017 K08M4_RS07530 fe06d44bb23d672cefe18984263093c2 224 Gene3D G3DSA:1.10.3480.10 19 208 2.8E-52 T 05-07-2017 IPR020945 DMSO/Nitrate reductase chaperone K08M4_RS07530 fe06d44bb23d672cefe18984263093c2 224 SUPERFAMILY SSF89155 20 205 9.42E-53 T 05-07-2017 IPR020945 DMSO/Nitrate reductase chaperone K08M4_RS07530 fe06d44bb23d672cefe18984263093c2 224 Pfam PF02613 Nitrate reductase delta subunit 58 172 8.1E-29 T 05-07-2017 IPR020945 DMSO/Nitrate reductase chaperone K08M4_RS02530 ceaec2d663513be31654b3b9ceebe620 348 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 185 336 4.5E-23 T 05-07-2017 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS02530 ceaec2d663513be31654b3b9ceebe620 348 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 9 170 3.0E-41 T 05-07-2017 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS02530 ceaec2d663513be31654b3b9ceebe620 348 SUPERFAMILY SSF55120 6 337 4.17E-91 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS02530 ceaec2d663513be31654b3b9ceebe620 348 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 6 341 27.502 T 05-07-2017 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS02530 ceaec2d663513be31654b3b9ceebe620 348 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 78 91 - T 05-07-2017 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 K08M4_RS02530 ceaec2d663513be31654b3b9ceebe620 348 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 9 224 7.8E-54 T 05-07-2017 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS16350 3054fcd907af2e7da104cbc692b4c264 137 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 135 1.9E-21 T 05-07-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 K08M4_RS09210 f0050768193ab214c93290d61f4fda1b 163 Gene3D G3DSA:3.40.1280.10 15 150 6.4E-17 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal K08M4_RS09210 f0050768193ab214c93290d61f4fda1b 163 Pfam PF00588 SpoU rRNA Methylase family 16 147 1.2E-18 T 05-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 K08M4_RS09210 f0050768193ab214c93290d61f4fda1b 163 SUPERFAMILY SSF75217 13 150 1.52E-27 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases K08M4_RS11145 b4d986398b9bc6a9aec9b2f0f5ec620b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 91 102 2.5E-48 T 05-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS11145 b4d986398b9bc6a9aec9b2f0f5ec620b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 172 185 2.5E-48 T 05-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS11145 b4d986398b9bc6a9aec9b2f0f5ec620b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 116 134 2.5E-48 T 05-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS11145 b4d986398b9bc6a9aec9b2f0f5ec620b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 200 209 2.5E-48 T 05-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS11145 b4d986398b9bc6a9aec9b2f0f5ec620b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 156 169 2.5E-48 T 05-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS11145 b4d986398b9bc6a9aec9b2f0f5ec620b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 137 153 2.5E-48 T 05-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS11145 b4d986398b9bc6a9aec9b2f0f5ec620b 319 SUPERFAMILY SSF52096 5 318 7.66E-104 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS11145 b4d986398b9bc6a9aec9b2f0f5ec620b 319 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 319 1.0E-162 T 05-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS11145 b4d986398b9bc6a9aec9b2f0f5ec620b 319 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 319 50.427 T 05-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS11145 b4d986398b9bc6a9aec9b2f0f5ec620b 319 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 6 151 2.0E-62 T 05-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 K08M4_RS11145 b4d986398b9bc6a9aec9b2f0f5ec620b 319 Gene3D G3DSA:3.90.226.10 58 274 1.0E-47 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS06540 f292cb38f534adda87642c62f43f3325 231 SUPERFAMILY SSF51735 7 220 1.97E-36 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS06540 f292cb38f534adda87642c62f43f3325 231 Gene3D G3DSA:3.40.50.720 8 228 4.6E-40 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS06540 f292cb38f534adda87642c62f43f3325 231 Pfam PF08732 HIM1 77 171 6.7E-10 T 05-07-2017 IPR014843 Protein Him1/Fmp52 K08M4_RS07470 07573be0820e11fd8d282b74578682e6 239 SUPERFAMILY SSF52540 5 217 1.89E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07470 07573be0820e11fd8d282b74578682e6 239 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS07470 07573be0820e11fd8d282b74578682e6 239 Gene3D G3DSA:3.40.50.300 6 230 1.2E-49 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07470 07573be0820e11fd8d282b74578682e6 239 SMART SM00382 29 213 2.0E-7 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS07470 07573be0820e11fd8d282b74578682e6 239 Pfam PF00005 ABC transporter 25 165 4.1E-27 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS19450 8cb1c0cd76406188f8d0487fa0ee52cc 328 Pfam PF02653 Branched-chain amino acid transport system / permease component 52 320 3.1E-52 T 05-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 K08M4_RS07815 d309f24002da3135bceb62c16e52f638 72 Pfam PF11197 Protein of unknown function (DUF2835) 4 70 1.5E-28 T 05-07-2017 IPR021363 Protein of unknown function DUF2835 K08M4_RS08575 60b56e82e72bf7c4be77e116548ae0cf 213 Gene3D G3DSA:2.40.160.20 34 176 9.7E-9 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS08575 60b56e82e72bf7c4be77e116548ae0cf 213 SUPERFAMILY SSF56925 33 176 1.26E-9 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS08575 60b56e82e72bf7c4be77e116548ae0cf 213 Pfam PF13505 Outer membrane protein beta-barrel domain 11 159 6.9E-7 T 05-07-2017 IPR027385 Outer membrane protein beta-barrel K08M4_RS04230 414b29a54ace6f1403277dcaafc18147 503 SMART SM00382 289 427 2.0E-6 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS04230 414b29a54ace6f1403277dcaafc18147 503 Pfam PF00448 SRP54-type protein, GTPase domain 292 480 6.3E-39 T 05-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 K08M4_RS04230 414b29a54ace6f1403277dcaafc18147 503 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 2 378 1.9E-85 T 05-07-2017 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 K08M4_RS04230 414b29a54ace6f1403277dcaafc18147 503 SMART SM00962 290 483 3.1E-64 T 05-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 K08M4_RS04230 414b29a54ace6f1403277dcaafc18147 503 Gene3D G3DSA:1.20.120.140 261 301 1.2E-4 T 05-07-2017 K08M4_RS04230 414b29a54ace6f1403277dcaafc18147 503 SUPERFAMILY SSF52540 286 478 7.88E-34 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04230 414b29a54ace6f1403277dcaafc18147 503 Gene3D G3DSA:3.40.50.300 302 480 2.9E-44 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS10320 224bef1a40ae8a5aee195021594f891e 266 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 16 262 4.5E-76 T 05-07-2017 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 K08M4_RS10320 224bef1a40ae8a5aee195021594f891e 266 Pfam PF12697 Alpha/beta hydrolase family 19 254 2.2E-13 T 05-07-2017 IPR000073 Alpha/beta hydrolase fold-1 K08M4_RS10320 224bef1a40ae8a5aee195021594f891e 266 Gene3D G3DSA:3.40.50.1820 13 263 6.9E-51 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS10320 224bef1a40ae8a5aee195021594f891e 266 SUPERFAMILY SSF53474 12 262 7.77E-37 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS10320 224bef1a40ae8a5aee195021594f891e 266 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 3 263 32.021 T 05-07-2017 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 K08M4_RS10640 46ab355ab8ca8dfd78e528add2771d13 149 SUPERFAMILY SSF46785 5 131 6.82E-42 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS10640 46ab355ab8ca8dfd78e528add2771d13 149 Gene3D G3DSA:1.10.10.10 2 82 1.5E-30 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS10640 46ab355ab8ca8dfd78e528add2771d13 149 Pfam PF01475 Ferric uptake regulator family 11 130 1.5E-46 T 05-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 K08M4_RS15975 96f56e9754a5da040db78d53f96e1046 273 Gene3D G3DSA:3.40.190.10 231 272 4.7E-4 T 05-07-2017 K08M4_RS15975 96f56e9754a5da040db78d53f96e1046 273 Gene3D G3DSA:3.40.190.10 25 105 4.7E-4 T 05-07-2017 K08M4_RS15975 96f56e9754a5da040db78d53f96e1046 273 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 21 271 8.0E-77 T 05-07-2017 IPR011862 Phosphate binding protein GO:0006810 K08M4_RS15975 96f56e9754a5da040db78d53f96e1046 273 Gene3D G3DSA:3.40.190.10 106 230 3.0E-45 T 05-07-2017 K08M4_RS15975 96f56e9754a5da040db78d53f96e1046 273 Pfam PF12849 PBP superfamily domain 20 259 2.6E-40 T 05-07-2017 IPR024370 PBP domain K08M4_RS15975 96f56e9754a5da040db78d53f96e1046 273 SUPERFAMILY SSF53850 16 273 7.41E-72 T 05-07-2017 K08M4_RS01615 5c57b2f25d6195c048cd59a14a231480 282 SUPERFAMILY SSF103481 178 276 1.24E-12 T 05-07-2017 K08M4_RS01615 5c57b2f25d6195c048cd59a14a231480 282 SUPERFAMILY SSF103481 40 141 3.01E-13 T 05-07-2017 K08M4_RS01615 5c57b2f25d6195c048cd59a14a231480 282 Pfam PF00892 EamA-like transporter family 143 268 5.0E-9 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS01615 5c57b2f25d6195c048cd59a14a231480 282 Pfam PF00892 EamA-like transporter family 6 137 9.3E-15 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS07780 3687c08608f85566918e68d89fd1b722 569 TIGRFAM TIGR03501 GlyGly_CTERM: GlyGly-CTERM domain 548 568 4.5E-5 T 05-07-2017 IPR020008 GlyGly-CTERM domain K08M4_RS07780 3687c08608f85566918e68d89fd1b722 569 Pfam PF11949 Protein of unknown function (DUF3466) 231 567 3.4E-58 T 05-07-2017 IPR022562 Protein of unknown function DUF3466 K08M4_RS10505 0f55a9e912d48c4c485100c6ae36c147 201 Gene3D G3DSA:3.10.180.10 2 198 1.0E-71 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS10505 0f55a9e912d48c4c485100c6ae36c147 201 Pfam PF06185 YecM protein 12 196 5.5E-69 T 05-07-2017 IPR010393 Protein of unknown function DUF991 K08M4_RS10505 0f55a9e912d48c4c485100c6ae36c147 201 SUPERFAMILY SSF54593 3 197 6.19E-66 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS11255 9e3d220fd53eab0343ca1bfd4d83b88b 104 PIRSF PIRSF006257 1 104 8.9E-36 T 05-07-2017 IPR007384 Protein of unknown function UCP006257 K08M4_RS11255 9e3d220fd53eab0343ca1bfd4d83b88b 104 Pfam PF04287 tRNA pseudouridine synthase C 10 101 2.8E-31 T 05-07-2017 IPR023376 YqcC-like domain K08M4_RS11255 9e3d220fd53eab0343ca1bfd4d83b88b 104 Gene3D G3DSA:1.20.1440.40 2 103 7.5E-34 T 05-07-2017 IPR023376 YqcC-like domain K08M4_RS11255 9e3d220fd53eab0343ca1bfd4d83b88b 104 SUPERFAMILY SSF158452 1 103 6.02E-34 T 05-07-2017 IPR023376 YqcC-like domain K08M4_RS20770 10d45e9b6c23505fc9b932d3f7d9de25 337 SUPERFAMILY SSF161098 97 295 1.96E-12 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS20770 10d45e9b6c23505fc9b932d3f7d9de25 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 309 2.5E-31 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS20770 10d45e9b6c23505fc9b932d3f7d9de25 337 Gene3D G3DSA:1.10.3720.10 95 306 1.5E-13 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS04930 91cd17a0e287b25e4731dd87611cd27a 159 Gene3D G3DSA:3.30.70.640 3 158 1.7E-69 T 05-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 K08M4_RS04930 91cd17a0e287b25e4731dd87611cd27a 159 SUPERFAMILY SSF55040 11 155 3.01E-61 T 05-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 K08M4_RS04930 91cd17a0e287b25e4731dd87611cd27a 159 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 152 6.2E-71 T 05-07-2017 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 K08M4_RS04930 91cd17a0e287b25e4731dd87611cd27a 159 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 158 35.894 T 05-07-2017 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type Reactome: R-HSA-947581 K08M4_RS04930 91cd17a0e287b25e4731dd87611cd27a 159 Pfam PF01967 MoaC family 15 150 1.8E-55 T 05-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 K08M4_RS05350 acd7d7cd9218863512af5dc3dac5f380 242 SUPERFAMILY SSF55120 56 241 1.92E-43 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS05350 acd7d7cd9218863512af5dc3dac5f380 242 Pfam PF00849 RNA pseudouridylate synthase 69 212 1.7E-15 T 05-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS05350 acd7d7cd9218863512af5dc3dac5f380 242 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 73 241 1.6E-56 T 05-07-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 K08M4_RS05350 acd7d7cd9218863512af5dc3dac5f380 242 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 104 118 - T 05-07-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 K08M4_RS06925 ad7b77f3db854c71f0064e75c1698ba2 193 Gene3D G3DSA:2.40.160.20 11 193 7.7E-37 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS06925 ad7b77f3db854c71f0064e75c1698ba2 193 Pfam PF13505 Outer membrane protein beta-barrel domain 7 193 2.0E-24 T 05-07-2017 IPR027385 Outer membrane protein beta-barrel K08M4_RS06925 ad7b77f3db854c71f0064e75c1698ba2 193 SUPERFAMILY SSF56925 25 193 9.42E-27 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS19130 fc514d6c116e6ef7d473f519be8242a4 110 Pfam PF01627 Hpt domain 21 90 4.5E-8 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS19130 fc514d6c116e6ef7d473f519be8242a4 110 SUPERFAMILY SSF47226 1 108 1.16E-18 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS19130 fc514d6c116e6ef7d473f519be8242a4 110 Gene3D G3DSA:1.20.120.160 1 92 1.1E-14 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS16435 0042f54a79a118aa213df7c2939ce005 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 62 3.5E-16 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS16435 0042f54a79a118aa213df7c2939ce005 298 SUPERFAMILY SSF46785 9 88 2.12E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS16435 0042f54a79a118aa213df7c2939ce005 298 Pfam PF03466 LysR substrate binding domain 88 289 1.1E-27 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS16435 0042f54a79a118aa213df7c2939ce005 298 Gene3D G3DSA:3.40.190.10 180 256 3.5E-14 T 05-07-2017 K08M4_RS16435 0042f54a79a118aa213df7c2939ce005 298 Gene3D G3DSA:3.40.190.10 92 179 3.8E-14 T 05-07-2017 K08M4_RS16435 0042f54a79a118aa213df7c2939ce005 298 SUPERFAMILY SSF53850 90 292 2.17E-29 T 05-07-2017 K08M4_RS16435 0042f54a79a118aa213df7c2939ce005 298 Gene3D G3DSA:1.10.10.10 7 86 1.6E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS04645 ceedc285e53517f9309261d1d9812953 628 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 13 502 9.8E-160 T 05-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 K08M4_RS04645 ceedc285e53517f9309261d1d9812953 628 ProSitePatterns PS01303 BCCT family of transporters signature. 321 330 - T 05-07-2017 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 K08M4_RS04645 ceedc285e53517f9309261d1d9812953 628 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 50 503 5.4E-147 T 05-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 K08M4_RS15020 03e008258e97a66204cef964b1fc4f73 405 Gene3D G3DSA:3.40.50.300 105 369 8.3E-36 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15020 03e008258e97a66204cef964b1fc4f73 405 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 113 352 6.2E-23 T 05-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain K08M4_RS15020 03e008258e97a66204cef964b1fc4f73 405 SUPERFAMILY SSF52540 108 368 2.58E-32 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS20735 02733a656f90b7c25ce1b2ba6be182cf 204 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 11 188 6.3E-32 T 05-07-2017 IPR003740 Uncharacterised membrane protein YitT K08M4_RS05690 eb907050a34e1a598b4cfdba72000942 154 Pfam PF04138 GtrA-like protein 30 152 2.2E-22 T 05-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 K08M4_RS02260 2aaf3a9153728623ff35d879f2499248 398 SUPERFAMILY SSF111342 8 299 1.09E-70 T 05-07-2017 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 K08M4_RS02260 2aaf3a9153728623ff35d879f2499248 398 Gene3D G3DSA:3.30.2110.10 20 196 6.3E-51 T 05-07-2017 K08M4_RS02260 2aaf3a9153728623ff35d879f2499248 398 Pfam PF01888 CbiD 18 282 1.2E-79 T 05-07-2017 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 K08M4_RS02260 2aaf3a9153728623ff35d879f2499248 398 PIRSF PIRSF026782 14 385 5.4E-99 T 05-07-2017 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 K08M4_RS02260 2aaf3a9153728623ff35d879f2499248 398 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 18 379 24.87 T 05-07-2017 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 K08M4_RS17070 8d6c761463584400d6f736bb0ddcf8aa 377 SUPERFAMILY SSF111369 48 255 2.62E-14 T 05-07-2017 K08M4_RS17070 8d6c761463584400d6f736bb0ddcf8aa 377 Gene3D G3DSA:2.40.50.100 57 90 4.3E-11 T 05-07-2017 K08M4_RS17070 8d6c761463584400d6f736bb0ddcf8aa 377 Gene3D G3DSA:2.40.50.100 174 196 4.3E-11 T 05-07-2017 K08M4_RS17070 8d6c761463584400d6f736bb0ddcf8aa 377 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 34 369 2.8E-34 T 05-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 K08M4_RS17070 8d6c761463584400d6f736bb0ddcf8aa 377 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 56 257 4.3E-16 T 05-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain K08M4_RS00730 0330de6ed9d84e73ad59bc3bfb0be330 117 Pfam PF13358 DDE superfamily endonuclease 5 85 8.6E-17 T 05-07-2017 K08M4_RS08325 1070594b9256c0660c2694e7c14148a3 164 Pfam PF13505 Outer membrane protein beta-barrel domain 5 157 2.6E-12 T 05-07-2017 IPR027385 Outer membrane protein beta-barrel K08M4_RS08325 1070594b9256c0660c2694e7c14148a3 164 Gene3D G3DSA:2.40.160.20 5 154 8.5E-17 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS08325 1070594b9256c0660c2694e7c14148a3 164 SUPERFAMILY SSF56925 18 156 1.83E-18 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS08120 c759907f20a867eb946f31d617bd1629 384 Pfam PF12698 ABC-2 family transporter protein 21 369 5.6E-41 T 05-07-2017 K08M4_RS16925 e9c3625dfd112217a8f54e4677651a22 338 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 35 315 7.8E-48 T 05-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 K08M4_RS16925 e9c3625dfd112217a8f54e4677651a22 338 SUPERFAMILY SSF53850 122 260 9.19E-5 T 05-07-2017 K08M4_RS15365 438bcf7b5ec6997db005fce46336240f 206 Gene3D G3DSA:3.40.50.1000 5 199 1.2E-35 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS15365 438bcf7b5ec6997db005fce46336240f 206 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 124 186 1.6E-12 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS15365 438bcf7b5ec6997db005fce46336240f 206 Pfam PF13419 Haloacid dehalogenase-like hydrolase 89 185 1.3E-10 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS15365 438bcf7b5ec6997db005fce46336240f 206 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 2.3E-8 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS15365 438bcf7b5ec6997db005fce46336240f 206 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 132 148 2.3E-8 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS15365 438bcf7b5ec6997db005fce46336240f 206 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 101 114 2.3E-8 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS15365 438bcf7b5ec6997db005fce46336240f 206 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 170 2.3E-8 T 05-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 K08M4_RS15365 438bcf7b5ec6997db005fce46336240f 206 SUPERFAMILY SSF56784 7 198 7.33E-34 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS13745 31b10f05a38c03f319a875b203d38109 182 Pfam PF02397 Bacterial sugar transferase 4 173 5.5E-47 T 05-07-2017 IPR003362 Bacterial sugar transferase K08M4_RS02720 79d7477fd479c270084d19d032f6f838 522 Pfam PF04262 Glutamate-cysteine ligase 13 378 4.9E-167 T 05-07-2017 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 K08M4_RS02720 79d7477fd479c270084d19d032f6f838 522 SUPERFAMILY SSF55931 6 513 3.6E-201 T 05-07-2017 K08M4_RS02720 79d7477fd479c270084d19d032f6f838 522 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 522 222.208 T 05-07-2017 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 K08M4_RS02720 79d7477fd479c270084d19d032f6f838 522 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 8 515 2.9E-208 T 05-07-2017 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 K08M4_RS04770 e13da42f3b85915e192bf2b09270a297 514 Gene3D G3DSA:1.20.120.160 400 510 1.4E-16 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS04770 e13da42f3b85915e192bf2b09270a297 514 SUPERFAMILY SSF47226 403 509 3.14E-14 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS04770 e13da42f3b85915e192bf2b09270a297 514 Pfam PF01627 Hpt domain 425 501 3.7E-8 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS15045 41f3a025980e2c1c03b18bc36973adb3 540 Gene3D G3DSA:3.40.720.10 226 529 5.8E-12 T 05-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 K08M4_RS15045 41f3a025980e2c1c03b18bc36973adb3 540 Pfam PF00884 Sulfatase 235 524 1.3E-44 T 05-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 K08M4_RS15045 41f3a025980e2c1c03b18bc36973adb3 540 Pfam PF08019 Domain of unknown function (DUF1705) 56 206 5.3E-50 T 05-07-2017 IPR012549 Domain of unknown function DUF1705 GO:0016021 K08M4_RS15045 41f3a025980e2c1c03b18bc36973adb3 540 SUPERFAMILY SSF53649 265 528 2.8E-16 T 05-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 K08M4_RS05560 8d3eee22aa58369b34374f73f8999eb9 227 Pfam PF01618 MotA/TolQ/ExbB proton channel family 79 207 7.6E-43 T 05-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 K08M4_RS05560 8d3eee22aa58369b34374f73f8999eb9 227 TIGRFAM TIGR02796 tolQ: protein TolQ 6 220 1.8E-92 T 05-07-2017 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 K08M4_RS21250 5681042257973c518c5fbe03c3c0c9cf 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 280 4.3E-20 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS21250 5681042257973c518c5fbe03c3c0c9cf 297 SUPERFAMILY SSF161098 28 297 4.49E-62 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS21250 5681042257973c518c5fbe03c3c0c9cf 297 Gene3D G3DSA:1.10.3720.10 29 283 5.4E-55 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS14600 d9ce3f54bbaeed06df77aac742767954 325 SUPERFAMILY SSF161098 89 302 1.83E-14 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS14600 d9ce3f54bbaeed06df77aac742767954 325 Gene3D G3DSA:1.10.3720.10 88 312 2.7E-15 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS14600 d9ce3f54bbaeed06df77aac742767954 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 318 1.5E-36 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS21185 5d2b6a1ecfc9c231c1b261f3abc74759 94 Pfam PF14542 GCN5-related N-acetyl-transferase 16 89 2.5E-20 T 05-07-2017 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase K08M4_RS21185 5d2b6a1ecfc9c231c1b261f3abc74759 94 SUPERFAMILY SSF55729 2 90 2.85E-21 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS21185 5d2b6a1ecfc9c231c1b261f3abc74759 94 Gene3D G3DSA:3.40.630.30 7 92 1.9E-21 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS04505 679dd671beaa5f5cc76498e04de750e1 176 Pfam PF04315 Elongation factor P hydroxylase 11 170 6.6E-71 T 05-07-2017 IPR007411 Elongation factor P hydroxylase K08M4_RS04940 e73beed19f3101e6fe154e96987e7c98 157 Gene3D G3DSA:3.90.1170.40 10 155 2.3E-57 T 05-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS04940 e73beed19f3101e6fe154e96987e7c98 157 Pfam PF02391 MoaE protein 14 126 3.0E-37 T 05-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS04940 e73beed19f3101e6fe154e96987e7c98 157 SUPERFAMILY SSF54690 10 155 4.18E-55 T 05-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 K08M4_RS06330 e4a3c9eb623835676a3a5f28891d1e9e 192 Pfam PF01965 DJ-1/PfpI family 3 168 6.0E-21 T 05-07-2017 IPR002818 DJ-1/PfpI K08M4_RS06330 e4a3c9eb623835676a3a5f28891d1e9e 192 SUPERFAMILY SSF52317 1 189 1.51E-48 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS06330 e4a3c9eb623835676a3a5f28891d1e9e 192 Gene3D G3DSA:3.40.50.880 1 189 1.7E-50 T 05-07-2017 IPR029062 Class I glutamine amidotransferase-like K08M4_RS14770 14b62e350de3b0dd75b80691009e48a2 189 SUPERFAMILY SSF57783 16 64 4.25E-14 T 05-07-2017 K08M4_RS14770 14b62e350de3b0dd75b80691009e48a2 189 SUPERFAMILY SSF57783 102 146 1.87E-7 T 05-07-2017 K08M4_RS14770 14b62e350de3b0dd75b80691009e48a2 189 Gene3D G3DSA:3.30.65.10 17 61 4.0E-14 T 05-07-2017 K08M4_RS14770 14b62e350de3b0dd75b80691009e48a2 189 Gene3D G3DSA:3.30.65.10 102 146 1.7E-9 T 05-07-2017 K08M4_RS14770 14b62e350de3b0dd75b80691009e48a2 189 Gene3D G3DSA:3.30.65.10 67 100 1.7E-13 T 05-07-2017 K08M4_RS14770 14b62e350de3b0dd75b80691009e48a2 189 SUPERFAMILY SSF57783 66 101 2.38E-12 T 05-07-2017 K08M4_RS14770 14b62e350de3b0dd75b80691009e48a2 189 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 115 151 7.4E-16 T 05-07-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 K08M4_RS14770 14b62e350de3b0dd75b80691009e48a2 189 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 21 57 2.4E-14 T 05-07-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 K08M4_RS14770 14b62e350de3b0dd75b80691009e48a2 189 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 67 103 1.3E-15 T 05-07-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 K08M4_RS00895 a8c4a85ba86b405704492f064e4e4b38 146 Pfam PF00376 MerR family regulatory protein 4 40 3.2E-16 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 K08M4_RS00895 a8c4a85ba86b405704492f064e4e4b38 146 SUPERFAMILY SSF46955 2 121 7.33E-32 T 05-07-2017 IPR009061 Putative DNA-binding domain K08M4_RS00895 a8c4a85ba86b405704492f064e4e4b38 146 TIGRFAM TIGR02043 ZntR: Zn(II)-responsive transcriptional regulator 1 131 4.1E-62 T 05-07-2017 IPR011788 Zn(II)-responsive transcriptional regulator GO:0003677|GO:0006351|GO:0008270 K08M4_RS00895 a8c4a85ba86b405704492f064e4e4b38 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 2.9E-9 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 K08M4_RS00895 a8c4a85ba86b405704492f064e4e4b38 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 2.9E-9 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 K08M4_RS00895 a8c4a85ba86b405704492f064e4e4b38 146 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 2.9E-9 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 K08M4_RS00895 a8c4a85ba86b405704492f064e4e4b38 146 SMART SM00422 2 71 5.3E-27 T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 K08M4_RS00895 a8c4a85ba86b405704492f064e4e4b38 146 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 05-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 K08M4_RS00895 a8c4a85ba86b405704492f064e4e4b38 146 Gene3D G3DSA:1.10.1660.10 58 138 1.3E-24 T 05-07-2017 K08M4_RS00895 a8c4a85ba86b405704492f064e4e4b38 146 Gene3D G3DSA:1.10.1660.10 1 57 3.2E-26 T 05-07-2017 K08M4_RS00895 a8c4a85ba86b405704492f064e4e4b38 146 Pfam PF09278 MerR, DNA binding 47 109 1.5E-15 T 05-07-2017 IPR015358 Transcription regulator MerR, DNA binding K08M4_RS19065 98eec63607ca864266251c4a24816806 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 122 1.4E-10 T 05-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain K08M4_RS19065 98eec63607ca864266251c4a24816806 125 SUPERFAMILY SSF54593 5 122 5.36E-25 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS19065 98eec63607ca864266251c4a24816806 125 Gene3D G3DSA:3.10.180.10 7 124 4.3E-32 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS18090 ee4b5590bed500083887517459538be3 134 Pfam PF02472 Biopolymer transport protein ExbD/TolR 9 132 1.5E-28 T 05-07-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 K08M4_RS18245 ee4b5590bed500083887517459538be3 134 Pfam PF02472 Biopolymer transport protein ExbD/TolR 9 132 1.5E-28 T 05-07-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 K08M4_RS05865 d5d181792ce0553ff8da7bd6ff465459 70 Pfam PF09493 Tryptophan-rich protein (DUF2389) 12 70 1.3E-22 T 05-07-2017 IPR012663 Conserved hypothetical protein CHP02450, tryptophan-rich K08M4_RS05865 d5d181792ce0553ff8da7bd6ff465459 70 TIGRFAM TIGR02450 TIGR02450: tryptophan-rich conserved hypothetical protein 10 70 1.1E-21 T 05-07-2017 IPR012663 Conserved hypothetical protein CHP02450, tryptophan-rich K08M4_RS16965 aefff07db1535988a7499dd7ac4278f4 492 Gene3D G3DSA:1.20.1250.20 9 188 3.2E-17 T 05-07-2017 K08M4_RS16965 aefff07db1535988a7499dd7ac4278f4 492 SUPERFAMILY SSF103473 244 474 3.92E-22 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS16965 aefff07db1535988a7499dd7ac4278f4 492 SUPERFAMILY SSF103473 7 199 3.92E-22 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS16965 aefff07db1535988a7499dd7ac4278f4 492 Pfam PF00854 POT family 95 431 5.5E-16 T 05-07-2017 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 K08M4_RS04335 b62229ee9a2744a07b54c8bf962b4d91 420 SUPERFAMILY SSF56935 26 420 5.49E-102 T 05-07-2017 K08M4_RS04335 b62229ee9a2744a07b54c8bf962b4d91 420 Gene3D G3DSA:2.40.160.60 26 420 6.2E-125 T 05-07-2017 K08M4_RS04335 b62229ee9a2744a07b54c8bf962b4d91 420 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 19 420 8.2E-127 T 05-07-2017 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) K08M4_RS04070 4a26d54a2b993e7dd4234bd19cfeec65 258 Pfam PF02107 Flagellar L-ring protein 80 255 9.5E-56 T 05-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 K08M4_RS04070 4a26d54a2b993e7dd4234bd19cfeec65 258 Hamap MF_00415 Flagellar L-ring protein [flgH]. 1 258 26.801 T 05-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 K08M4_RS04070 4a26d54a2b993e7dd4234bd19cfeec65 258 PRINTS PR01008 Flagellar L-ring protein signature 221 235 2.3E-21 T 05-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 K08M4_RS04070 4a26d54a2b993e7dd4234bd19cfeec65 258 PRINTS PR01008 Flagellar L-ring protein signature 200 216 2.3E-21 T 05-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 K08M4_RS04070 4a26d54a2b993e7dd4234bd19cfeec65 258 PRINTS PR01008 Flagellar L-ring protein signature 237 251 2.3E-21 T 05-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 K08M4_RS04070 4a26d54a2b993e7dd4234bd19cfeec65 258 PRINTS PR01008 Flagellar L-ring protein signature 102 114 2.3E-21 T 05-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 K08M4_RS04070 4a26d54a2b993e7dd4234bd19cfeec65 258 PRINTS PR01008 Flagellar L-ring protein signature 174 189 2.3E-21 T 05-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 K08M4_RS07900 e4d662f75478ec36938fd3314647861f 342 Gene3D G3DSA:3.40.190.10 229 257 1.1E-17 T 05-07-2017 K08M4_RS07900 e4d662f75478ec36938fd3314647861f 342 Gene3D G3DSA:3.40.190.10 36 129 1.1E-17 T 05-07-2017 K08M4_RS07900 e4d662f75478ec36938fd3314647861f 342 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 257 2.6E-29 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS07900 e4d662f75478ec36938fd3314647861f 342 SUPERFAMILY SSF53850 29 258 8.7E-48 T 05-07-2017 K08M4_RS07900 e4d662f75478ec36938fd3314647861f 342 Gene3D G3DSA:3.40.190.10 130 228 1.6E-12 T 05-07-2017 K08M4_RS07900 e4d662f75478ec36938fd3314647861f 342 SMART SM00062 38 267 2.4E-52 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS09280 542af4b23df9c575b4e510ada54c6f69 232 Pfam PF00849 RNA pseudouridylate synthase 10 153 2.9E-28 T 05-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS09280 542af4b23df9c575b4e510ada54c6f69 232 TIGRFAM TIGR01621 RluA-like: pseudouridine synthase Rlu family protein, TIGR01621 1 220 9.8E-106 T 05-07-2017 IPR006508 Pseudouridine synthase, RluA-like K08M4_RS09280 542af4b23df9c575b4e510ada54c6f69 232 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 47 61 - T 05-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS09280 542af4b23df9c575b4e510ada54c6f69 232 SUPERFAMILY SSF55120 2 194 7.68E-48 T 05-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 K08M4_RS03460 5cce7296388174f3bdb6cfb829d1d327 429 PIRSF PIRSF005353 1 429 6.5E-188 T 05-07-2017 IPR026033 Purine permease PbuG-like K08M4_RS03460 5cce7296388174f3bdb6cfb829d1d327 429 Pfam PF00860 Permease family 17 391 7.1E-55 T 05-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 K08M4_RS10015 af3301ca3bed4e7596d90d413d04960d 401 Pfam PF07690 Major Facilitator Superfamily 16 357 2.7E-23 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS10015 af3301ca3bed4e7596d90d413d04960d 401 SUPERFAMILY SSF103473 5 394 6.54E-39 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS10015 af3301ca3bed4e7596d90d413d04960d 401 Gene3D G3DSA:1.20.1250.20 214 394 2.8E-8 T 05-07-2017 K08M4_RS10015 af3301ca3bed4e7596d90d413d04960d 401 Gene3D G3DSA:1.20.1250.20 9 202 1.3E-23 T 05-07-2017 K08M4_RS16520 198b2dc64dec1784c6f709288fe499d2 205 Gene3D G3DSA:3.40.50.150 41 143 1.0E-18 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS16520 198b2dc64dec1784c6f709288fe499d2 205 Pfam PF13649 Methyltransferase domain 54 138 2.6E-12 T 05-07-2017 K08M4_RS16520 198b2dc64dec1784c6f709288fe499d2 205 SUPERFAMILY SSF53335 41 136 5.63E-17 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS15135 52af4e792fedab3aacd5d3a8670ada62 260 SUPERFAMILY SSF46894 173 240 5.1E-16 T 05-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 K08M4_RS15135 52af4e792fedab3aacd5d3a8670ada62 260 SMART SM00421 178 235 1.5E-11 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS15135 52af4e792fedab3aacd5d3a8670ada62 260 Gene3D G3DSA:3.30.450.20 31 143 7.2E-5 T 05-07-2017 K08M4_RS15135 52af4e792fedab3aacd5d3a8670ada62 260 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 211 1.4E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS15135 52af4e792fedab3aacd5d3a8670ada62 260 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 195 1.4E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS15135 52af4e792fedab3aacd5d3a8670ada62 260 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 211 223 1.4E-8 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS15135 52af4e792fedab3aacd5d3a8670ada62 260 Gene3D G3DSA:1.10.10.10 174 240 3.9E-18 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS15135 52af4e792fedab3aacd5d3a8670ada62 260 Pfam PF08448 PAS fold 34 145 1.1E-20 T 05-07-2017 IPR013656 PAS fold-4 K08M4_RS15135 52af4e792fedab3aacd5d3a8670ada62 260 SUPERFAMILY SSF55785 33 144 2.86E-7 T 05-07-2017 IPR000014 PAS domain K08M4_RS15135 52af4e792fedab3aacd5d3a8670ada62 260 Pfam PF00196 Bacterial regulatory proteins, luxR family 180 235 1.1E-14 T 05-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 K08M4_RS16070 e04199904c42a556ed13948075abdafb 167 Gene3D G3DSA:3.10.129.10 14 154 3.0E-42 T 05-07-2017 IPR029069 HotDog domain K08M4_RS16070 e04199904c42a556ed13948075abdafb 167 Pfam PF03061 Thioesterase superfamily 28 102 3.0E-16 T 05-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 K08M4_RS16070 e04199904c42a556ed13948075abdafb 167 SUPERFAMILY SSF54637 11 156 1.15E-40 T 05-07-2017 IPR029069 HotDog domain K08M4_RS11385 76014da391120b01ccae1da91addfd7e 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 41 225 2.0E-23 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS11385 76014da391120b01ccae1da91addfd7e 227 Gene3D G3DSA:1.10.3720.10 18 226 6.0E-43 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS11385 76014da391120b01ccae1da91addfd7e 227 SUPERFAMILY SSF161098 17 212 6.28E-47 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS06465 c89696c884a7088238b5c707563b4898 186 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 79 112 1.1E-5 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS06465 c89696c884a7088238b5c707563b4898 186 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 16 44 2.0E-6 T 05-07-2017 IPR001451 Hexapeptide repeat K08M4_RS06465 c89696c884a7088238b5c707563b4898 186 SUPERFAMILY SSF51161 8 136 7.79E-29 T 05-07-2017 IPR011004 Trimeric LpxA-like K08M4_RS06465 c89696c884a7088238b5c707563b4898 186 Gene3D G3DSA:2.160.10.10 8 182 4.3E-35 T 05-07-2017 K08M4_RS04655 4265d5948cfd60338eb09ffc715ba4ed 319 Pfam PF04187 Haem-binding uptake, Tiki superfamily, ChaN 59 259 6.6E-54 T 05-07-2017 IPR007314 Haem-binding uptake, Tiki superfamily, ChaN K08M4_RS04655 4265d5948cfd60338eb09ffc715ba4ed 319 SUPERFAMILY SSF159501 36 287 1.99E-70 T 05-07-2017 K08M4_RS04655 4265d5948cfd60338eb09ffc715ba4ed 319 PIRSF PIRSF020419 1 303 1.0E-73 T 05-07-2017 IPR016773 Ferric uptake regulator, CjrA, predicted K08M4_RS03155 c736dcdac6ed27ec61757718fdceb7a9 135 Pfam PF12802 MarR family 29 87 7.5E-14 T 05-07-2017 K08M4_RS03155 c736dcdac6ed27ec61757718fdceb7a9 135 Gene3D G3DSA:1.10.10.10 5 133 1.6E-26 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS03155 c736dcdac6ed27ec61757718fdceb7a9 135 SMART SM00347 22 123 2.1E-14 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS03155 c736dcdac6ed27ec61757718fdceb7a9 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 1.2E-8 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS03155 c736dcdac6ed27ec61757718fdceb7a9 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 1.2E-8 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS03155 c736dcdac6ed27ec61757718fdceb7a9 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 1.2E-8 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS03155 c736dcdac6ed27ec61757718fdceb7a9 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 1.2E-8 T 05-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 K08M4_RS03155 c736dcdac6ed27ec61757718fdceb7a9 135 SUPERFAMILY SSF46785 27 133 2.56E-23 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21600 184b92230da007b8e3252bd74246a13c 195 Pfam PF16036 Chalcone isomerase-like 85 192 4.6E-13 T 05-07-2017 IPR016087 Chalcone isomerase GO:0016872 K08M4_RS07515 99b756deeff9f30f5abef9a4e615bbb6 154 Pfam PF11749 Protein of unknown function (DUF3305) 58 144 1.5E-19 T 05-07-2017 IPR021736 Protein of unknown function DUF3305 K08M4_RS12960 ba76f701bb1b380494010691931e58e9 431 SUPERFAMILY SSF109998 27 200 1.41E-35 T 05-07-2017 IPR027304 Trigger factor/SurA domain K08M4_RS12960 ba76f701bb1b380494010691931e58e9 431 Pfam PF09312 SurA N-terminal domain 27 144 1.3E-41 T 05-07-2017 IPR015391 SurA N-terminal K08M4_RS12960 ba76f701bb1b380494010691931e58e9 431 Hamap MF_01183 Chaperone SurA [surA]. 11 426 31.787 T 05-07-2017 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 K08M4_RS12960 ba76f701bb1b380494010691931e58e9 431 Gene3D G3DSA:3.10.50.40 171 274 2.4E-27 T 05-07-2017 K08M4_RS12960 ba76f701bb1b380494010691931e58e9 431 Gene3D G3DSA:3.10.50.40 281 404 7.9E-32 T 05-07-2017 K08M4_RS12960 ba76f701bb1b380494010691931e58e9 431 SUPERFAMILY SSF54534 175 273 3.86E-25 T 05-07-2017 K08M4_RS12960 ba76f701bb1b380494010691931e58e9 431 SUPERFAMILY SSF54534 281 383 5.49E-29 T 05-07-2017 K08M4_RS12960 ba76f701bb1b380494010691931e58e9 431 Pfam PF13616 PPIC-type PPIASE domain 168 272 4.5E-21 T 05-07-2017 K08M4_RS12960 ba76f701bb1b380494010691931e58e9 431 Pfam PF13616 PPIC-type PPIASE domain 279 381 1.3E-22 T 05-07-2017 K08M4_RS21210 882613fd289c201163b5d1a5cbbe956e 380 Gene3D G3DSA:3.40.50.1010 139 173 5.5E-4 T 05-07-2017 IPR029060 PIN domain-like K08M4_RS21210 882613fd289c201163b5d1a5cbbe956e 380 Gene3D G3DSA:3.40.50.1010 3 72 5.5E-4 T 05-07-2017 IPR029060 PIN domain-like K08M4_RS21855 ed2dd9b332c1ef625765083d9a82ccec 252 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 32 252 4.9E-12 T 05-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF K08M4_RS21855 ed2dd9b332c1ef625765083d9a82ccec 252 Gene3D G3DSA:3.40.190.10 213 252 1.8E-9 T 05-07-2017 K08M4_RS21855 ed2dd9b332c1ef625765083d9a82ccec 252 Gene3D G3DSA:3.40.190.10 32 111 1.8E-9 T 05-07-2017 K08M4_RS21855 ed2dd9b332c1ef625765083d9a82ccec 252 SUPERFAMILY SSF53850 32 252 1.3E-23 T 05-07-2017 K08M4_RS12895 621742f1db218659585f61945206aad7 356 TIGRFAM TIGR00661 MJ1255: conserved hypothetical protein 2 319 1.1E-96 T 05-07-2017 IPR005262 Conserved hypothetical protein CHP00661 K08M4_RS12895 621742f1db218659585f61945206aad7 356 Pfam PF13528 Glycosyl transferase family 1 1 307 1.2E-39 T 05-07-2017 K08M4_RS12895 621742f1db218659585f61945206aad7 356 SUPERFAMILY SSF53756 1 305 9.77E-11 T 05-07-2017 K08M4_RS00175 66d6f7ec2c9d056b1162ddbe382f4be6 69 Gene3D G3DSA:3.10.20.30 4 69 2.5E-22 T 05-07-2017 IPR012675 Beta-grasp domain K08M4_RS00175 66d6f7ec2c9d056b1162ddbe382f4be6 69 SUPERFAMILY SSF54285 4 69 5.82E-15 T 05-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp K08M4_RS00175 66d6f7ec2c9d056b1162ddbe382f4be6 69 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 6 69 4.1E-18 T 05-07-2017 IPR010035 ThiS, thiamine-biosynthesis K08M4_RS00175 66d6f7ec2c9d056b1162ddbe382f4be6 69 Pfam PF02597 ThiS family 8 69 2.5E-13 T 05-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 K08M4_RS01825 e9f22f796937866364cbf39e487b717f 187 PIRSF PIRSF028513 2 185 5.4E-27 T 05-07-2017 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 K08M4_RS01825 e9f22f796937866364cbf39e487b717f 187 Hamap MF_01915 Lipopolysaccharide export system protein LptC [lptC]. 3 185 24.499 T 05-07-2017 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 K08M4_RS01825 e9f22f796937866364cbf39e487b717f 187 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 8 183 2.2E-46 T 05-07-2017 IPR010664 Lipopolysaccharide assembly, LptC-related K08M4_RS01825 e9f22f796937866364cbf39e487b717f 187 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 5 182 9.4E-48 T 05-07-2017 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 K08M4_RS00515 986dc7cc8ee9438608ddfd0994f10ce3 109 Pfam PF10694 Protein of unknown function (DUF2500) 6 105 7.8E-25 T 05-07-2017 IPR019635 Protein of unknown function DUF2500 K08M4_RS07715 6ea326fd426d4d1f3d74c5280bfc213e 299 SUPERFAMILY SSF81301 28 91 2.34E-6 T 05-07-2017 K08M4_RS07715 6ea326fd426d4d1f3d74c5280bfc213e 299 Gene3D G3DSA:3.30.460.10 17 72 2.0E-4 T 05-07-2017 K08M4_RS08400 4af5adf3a48689d132b51566f5fce47b 149 SUPERFAMILY SSF158682 2 143 3.66E-29 T 05-07-2017 IPR029024 TerB-like K08M4_RS08400 4af5adf3a48689d132b51566f5fce47b 149 Pfam PF05099 Tellurite resistance protein TerB 15 142 2.5E-38 T 05-07-2017 IPR007791 Co-chaperone DjlA, N-terminal K08M4_RS08400 4af5adf3a48689d132b51566f5fce47b 149 Gene3D G3DSA:1.10.3680.10 3 140 7.5E-24 T 05-07-2017 IPR029024 TerB-like K08M4_RS20725 36cb86fe5833ee9f4d93c0c3d47999e1 98 Pfam PF12840 Helix-turn-helix domain 8 69 8.1E-12 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20725 36cb86fe5833ee9f4d93c0c3d47999e1 98 SUPERFAMILY SSF46785 2 93 3.04E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS20725 36cb86fe5833ee9f4d93c0c3d47999e1 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 5.9E-6 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS20725 36cb86fe5833ee9f4d93c0c3d47999e1 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 5.9E-6 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS20725 36cb86fe5833ee9f4d93c0c3d47999e1 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 5.9E-6 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS20725 36cb86fe5833ee9f4d93c0c3d47999e1 98 SMART SM00418 8 85 4.4E-5 T 05-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 K08M4_RS20725 36cb86fe5833ee9f4d93c0c3d47999e1 98 Gene3D G3DSA:1.10.10.10 1 96 6.1E-21 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS03380 3f99673c0bc252cef8d3d343b1efb6a4 404 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 155 344 6.3E-13 T 05-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain K08M4_RS03380 3f99673c0bc252cef8d3d343b1efb6a4 404 Gene3D G3DSA:3.40.50.300 151 386 3.4E-42 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03380 3f99673c0bc252cef8d3d343b1efb6a4 404 SUPERFAMILY SSF52540 152 385 5.76E-30 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS19720 5225b56a6c31b898cb5db1c54db6cb39 366 Pfam PF01594 Domain of unknown function DUF20 19 345 1.0E-36 T 05-07-2017 IPR002549 Transmembrane protein TqsA-like K08M4_RS17510 69b403f1d6ff13f3f3b7651d771e49cd 475 Pfam PF02321 Outer membrane efflux protein 50 232 3.7E-8 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS17510 69b403f1d6ff13f3f3b7651d771e49cd 475 Pfam PF02321 Outer membrane efflux protein 273 451 6.4E-13 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS17510 69b403f1d6ff13f3f3b7651d771e49cd 475 Gene3D G3DSA:1.20.1600.10 41 443 3.6E-29 T 05-07-2017 K08M4_RS17510 69b403f1d6ff13f3f3b7651d771e49cd 475 SUPERFAMILY SSF56954 26 452 2.88E-45 T 05-07-2017 K08M4_RS20255 ed7faa32fbf6e428582374ffd84dc0af 378 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 52 284 7.1E-13 T 05-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain K08M4_RS20255 ed7faa32fbf6e428582374ffd84dc0af 378 SUPERFAMILY SSF111369 49 291 7.19E-61 T 05-07-2017 K08M4_RS20255 ed7faa32fbf6e428582374ffd84dc0af 378 Gene3D G3DSA:2.40.50.100 60 92 8.1E-21 T 05-07-2017 K08M4_RS20255 ed7faa32fbf6e428582374ffd84dc0af 378 Gene3D G3DSA:2.40.50.100 167 199 8.1E-21 T 05-07-2017 K08M4_RS20255 ed7faa32fbf6e428582374ffd84dc0af 378 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 34 371 1.3E-78 T 05-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 K08M4_RS02215 c0d85720d0c72b87378edc7a1bb46bd2 354 Gene3D G3DSA:3.40.640.10 51 257 1.3E-37 T 05-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 K08M4_RS02215 c0d85720d0c72b87378edc7a1bb46bd2 354 SUPERFAMILY SSF53383 11 351 2.31E-41 T 05-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase K08M4_RS02215 c0d85720d0c72b87378edc7a1bb46bd2 354 Pfam PF00155 Aminotransferase class I and II 73 286 7.5E-21 T 05-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 K08M4_RS20070 93a9d414df6bac78069b42bd03e19114 179 Pfam PF06892 Phage regulatory protein CII (CP76) 10 169 7.7E-55 T 05-07-2017 IPR009679 Bacteriophage 186, CII K08M4_RS19995 371250b20742c42a8242781d7cbc3674 238 Pfam PF05944 Phage small terminase subunit 37 166 3.8E-35 T 05-07-2017 IPR010270 Bacteriophage P2, GpM GO:0003677|GO:0004519|GO:0019069 K08M4_RS05400 3fc8f912b62c14f2c5edcc893558a4a1 81 Pfam PF10692 Protein of unknown function (DUF2498) 3 79 1.3E-40 T 05-07-2017 IPR019633 Protein of unknown function DUF2498 K08M4_RS07420 780efbbe8d63a608d93b3579260895c0 288 Gene3D G3DSA:3.90.1200.10 101 250 7.4E-8 T 05-07-2017 K08M4_RS07420 780efbbe8d63a608d93b3579260895c0 288 SUPERFAMILY SSF56112 3 276 3.95E-38 T 05-07-2017 IPR011009 Protein kinase-like domain K08M4_RS07420 780efbbe8d63a608d93b3579260895c0 288 PIRSF PIRSF006221 1 288 3.7E-102 T 05-07-2017 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 K08M4_RS07420 780efbbe8d63a608d93b3579260895c0 288 Pfam PF03881 Fructosamine kinase 1 286 1.1E-123 T 05-07-2017 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 K08M4_RS06245 f03d14510b6fb004930bad46f977df0c 590 Pfam PF00474 Sodium:solute symporter family 32 417 9.0E-39 T 05-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 K08M4_RS00840 dd47f989bf4c29753abd797776f14303 165 Pfam PF04353 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ 3 155 1.4E-53 T 05-07-2017 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 K08M4_RS00840 dd47f989bf4c29753abd797776f14303 165 PIRSF PIRSF016548 3 165 9.7E-65 T 05-07-2017 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 K08M4_RS17875 6bd211acad7bdde8adf4b510d0f2ec0e 181 Gene3D G3DSA:3.40.630.30 1 161 6.9E-31 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS17875 6bd211acad7bdde8adf4b510d0f2ec0e 181 SUPERFAMILY SSF55729 1 144 1.48E-24 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS17875 6bd211acad7bdde8adf4b510d0f2ec0e 181 Pfam PF00583 Acetyltransferase (GNAT) family 64 141 2.4E-15 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS19195 c7ef1ae9414ecab5204f52ce80528a67 158 Gene3D G3DSA:3.40.190.10 44 151 1.2E-5 T 05-07-2017 K08M4_RS19195 c7ef1ae9414ecab5204f52ce80528a67 158 SUPERFAMILY SSF53850 38 155 1.41E-8 T 05-07-2017 K08M4_RS18045 87270a1eedc43255685184a81ee30211 198 Gene3D G3DSA:3.40.30.10 112 184 3.2E-4 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS18045 87270a1eedc43255685184a81ee30211 198 Pfam PF13778 Domain of unknown function (DUF4174) 82 188 6.2E-25 T 05-07-2017 IPR025232 Domain of unknown function DUF4174 K08M4_RS11060 a3888f8e6eabd503e6f0bff263adff79 208 Pfam PF14681 Uracil phosphoribosyltransferase 7 207 2.7E-62 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS11060 a3888f8e6eabd503e6f0bff263adff79 208 Gene3D G3DSA:3.40.50.2020 2 208 1.4E-72 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS11060 a3888f8e6eabd503e6f0bff263adff79 208 SUPERFAMILY SSF53271 3 206 4.85E-66 T 05-07-2017 IPR029057 Phosphoribosyltransferase-like K08M4_RS11060 a3888f8e6eabd503e6f0bff263adff79 208 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 43.863 T 05-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 K08M4_RS11060 a3888f8e6eabd503e6f0bff263adff79 208 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 2 208 5.7E-90 T 05-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 K08M4_RS01695 7f63092727349836c08453c0e3756040 419 Pfam PF02687 FtsX-like permease family 292 410 5.7E-19 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 K08M4_RS01695 7f63092727349836c08453c0e3756040 419 Pfam PF12704 MacB-like periplasmic core domain 20 260 4.4E-11 T 05-07-2017 IPR025857 MacB-like periplasmic core domain K08M4_RS03315 64d3ff3f8436a5225977ac6063797275 185 Pfam PF07811 TadE-like protein 13 53 4.3E-7 T 05-07-2017 IPR012495 TadE-like K08M4_RS09960 8a9c23217d6cb73ada7caeb8f97c5785 329 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 71 240 1.5E-7 T 05-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain K08M4_RS09960 8a9c23217d6cb73ada7caeb8f97c5785 329 Gene3D G3DSA:2.40.50.100 74 97 2.9E-7 T 05-07-2017 K08M4_RS09960 8a9c23217d6cb73ada7caeb8f97c5785 329 Gene3D G3DSA:2.40.50.100 170 192 2.9E-7 T 05-07-2017 K08M4_RS09960 8a9c23217d6cb73ada7caeb8f97c5785 329 SUPERFAMILY SSF111369 69 194 7.06E-6 T 05-07-2017 K08M4_RS03915 173e44595328ff6b3bc75d556242bbad 207 Pfam PF11659 Protein of unknown function (DUF3261) 13 168 3.4E-44 T 05-07-2017 IPR021675 Protein of unknown function DUF3261 K08M4_RS18555 ce67c0dfa80695a7745eaea0470e3b83 123 Pfam PF11782 Protein of unknown function (DUF3319) 1 88 1.6E-40 T 05-07-2017 IPR021753 Protein of unknown function DUF3319 K08M4_RS05550 97df7d0646da7df1d0d7672dafc46299 100 TIGRFAM TIGR02112 cyd_oper_ybgE: cyd operon protein YbgE 8 99 2.0E-38 T 05-07-2017 IPR011846 Cyd operon protein YbgE K08M4_RS05550 97df7d0646da7df1d0d7672dafc46299 100 Pfam PF09600 Cyd operon protein YbgE (Cyd_oper_YbgE) 20 97 3.9E-30 T 05-07-2017 IPR011846 Cyd operon protein YbgE K08M4_RS06385 fa0282b329b226a5baa99607f10118ca 513 TIGRFAM TIGR00835 agcS: amino acid carrier protein 66 498 2.1E-114 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS06385 fa0282b329b226a5baa99607f10118ca 513 Pfam PF01235 Sodium:alanine symporter family 104 507 1.2E-124 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS06385 fa0282b329b226a5baa99607f10118ca 513 PRINTS PR00175 Sodium/alanine symporter signature 407 429 8.7E-44 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS06385 fa0282b329b226a5baa99607f10118ca 513 PRINTS PR00175 Sodium/alanine symporter signature 241 259 8.7E-44 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS06385 fa0282b329b226a5baa99607f10118ca 513 PRINTS PR00175 Sodium/alanine symporter signature 468 488 8.7E-44 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS06385 fa0282b329b226a5baa99607f10118ca 513 PRINTS PR00175 Sodium/alanine symporter signature 140 162 8.7E-44 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS06385 fa0282b329b226a5baa99607f10118ca 513 PRINTS PR00175 Sodium/alanine symporter signature 359 377 8.7E-44 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS06385 fa0282b329b226a5baa99607f10118ca 513 PRINTS PR00175 Sodium/alanine symporter signature 269 288 8.7E-44 T 05-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 K08M4_RS11675 e6ce9286e00b88b262a8caf938f64cc0 160 PRINTS PR00813 Bacterial general secretion pathway protein G signature 33 58 2.6E-6 T 05-07-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 K08M4_RS11675 e6ce9286e00b88b262a8caf938f64cc0 160 PRINTS PR00813 Bacterial general secretion pathway protein G signature 69 87 2.6E-6 T 05-07-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 K08M4_RS11675 e6ce9286e00b88b262a8caf938f64cc0 160 Pfam PF07963 Prokaryotic N-terminal methylation motif 32 50 5.5E-5 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS11675 e6ce9286e00b88b262a8caf938f64cc0 160 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 32 54 1.1E-8 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS11675 e6ce9286e00b88b262a8caf938f64cc0 160 Gene3D G3DSA:3.30.700.10 35 128 1.0E-13 T 05-07-2017 K08M4_RS11675 e6ce9286e00b88b262a8caf938f64cc0 160 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 32 52 - T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS11675 e6ce9286e00b88b262a8caf938f64cc0 160 SUPERFAMILY SSF54523 34 137 2.83E-17 T 05-07-2017 K08M4_RS11675 e6ce9286e00b88b262a8caf938f64cc0 160 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 55 137 3.0E-15 T 05-07-2017 IPR031982 Type IV minor pilin ComP K08M4_RS09870 10cb678271c92f26a3cf8957289eda53 196 TIGRFAM TIGR02722 lp_: uncharacterized lipoprotein 3 187 7.9E-72 T 05-07-2017 IPR014094 Penicillin-binding protein activator LpoB K08M4_RS09870 10cb678271c92f26a3cf8957289eda53 196 Pfam PF13036 Peptidoglycan-synthase activator LpoB 9 185 2.8E-64 T 05-07-2017 IPR014094 Penicillin-binding protein activator LpoB K08M4_RS17580 07ba1a8f1ee6243915569edf4f09d218 265 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 59 153 2.5E-24 T 05-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 K08M4_RS17580 07ba1a8f1ee6243915569edf4f09d218 265 SUPERFAMILY SSF161098 60 245 2.51E-43 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS17580 07ba1a8f1ee6243915569edf4f09d218 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 258 8.9E-20 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS17580 07ba1a8f1ee6243915569edf4f09d218 265 Gene3D G3DSA:1.10.3720.10 58 258 1.1E-47 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS17275 b260f889a36c5c713093de0c4813c938 288 Pfam PF00482 Type II secretion system (T2SS), protein F 152 278 7.1E-15 T 05-07-2017 IPR018076 Type II secretion system F domain K08M4_RS17900 0507f848bdf3972bfd75b7929b32b370 794 Pfam PF00577 Outer membrane usher protein 150 686 3.4E-17 T 05-07-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS02190 4827c4df6245fe36f507452861e6f5b2 1106 Gene3D G3DSA:2.60.120.200 780 832 2.0E-7 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain K08M4_RS02190 4827c4df6245fe36f507452861e6f5b2 1106 Gene3D G3DSA:2.60.120.200 697 733 2.0E-7 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain K08M4_RS02190 4827c4df6245fe36f507452861e6f5b2 1106 SUPERFAMILY SSF49899 607 742 5.39E-8 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain K08M4_RS02190 4827c4df6245fe36f507452861e6f5b2 1106 SUPERFAMILY SSF49899 798 838 5.39E-8 T 05-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain K08M4_RS03680 a3701f23f3b5cacb62850de50353883c 348 Gene3D G3DSA:2.130.10.10 6 345 3.5E-65 T 05-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 K08M4_RS03680 a3701f23f3b5cacb62850de50353883c 348 Pfam PF10282 Lactonase, 7-bladed beta-propeller 6 345 4.1E-88 T 05-07-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 K08M4_RS03680 a3701f23f3b5cacb62850de50353883c 348 SUPERFAMILY SSF51004 26 331 2.75E-23 T 05-07-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain K08M4_RS00225 fd57b8979a0901e696fb3f550a0d0f32 86 Pfam PF10048 Predicted integral membrane protein (DUF2282) 33 82 1.9E-22 T 05-07-2017 IPR018740 Protein of unknown function DUF2282, integral membrane K08M4_RS09335 d33c23b87f7b6720fc34852da9c7aa4c 223 TIGRFAM TIGR02977 phageshock_pspA: phage shock protein A 1 219 1.7E-93 T 05-07-2017 IPR014319 Phage shock protein, PspA K08M4_RS09335 d33c23b87f7b6720fc34852da9c7aa4c 223 Pfam PF04012 PspA/IM30 family 2 217 2.1E-62 T 05-07-2017 IPR007157 PspA/IM30 K08M4_RS08105 d3d8c5099250a1f3df4f3fc00fdcd23a 484 Gene3D G3DSA:1.20.1600.10 122 454 1.1E-50 T 05-07-2017 K08M4_RS08105 d3d8c5099250a1f3df4f3fc00fdcd23a 484 Gene3D G3DSA:1.20.1600.10 28 90 1.1E-50 T 05-07-2017 K08M4_RS08105 d3d8c5099250a1f3df4f3fc00fdcd23a 484 Pfam PF02321 Outer membrane efflux protein 32 251 8.1E-23 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS08105 d3d8c5099250a1f3df4f3fc00fdcd23a 484 Pfam PF02321 Outer membrane efflux protein 275 454 2.5E-26 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS08105 d3d8c5099250a1f3df4f3fc00fdcd23a 484 SUPERFAMILY SSF56954 2 83 1.83E-69 T 05-07-2017 K08M4_RS08105 d3d8c5099250a1f3df4f3fc00fdcd23a 484 SUPERFAMILY SSF56954 114 454 1.83E-69 T 05-07-2017 K08M4_RS04265 10b016e711f200e03514697a6ff81aca 260 Pfam PF13614 AAA domain 4 177 3.7E-52 T 05-07-2017 IPR025669 AAA domain K08M4_RS04265 10b016e711f200e03514697a6ff81aca 260 Gene3D G3DSA:3.40.50.300 3 248 3.5E-58 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04265 10b016e711f200e03514697a6ff81aca 260 SUPERFAMILY SSF52540 1 253 1.81E-56 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09800 2b9e3c8654d60e2e6da2d6ef50f4a7b1 335 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 18 323 3.5E-108 T 05-07-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 K08M4_RS09800 2b9e3c8654d60e2e6da2d6ef50f4a7b1 335 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 1 328 40.191 T 05-07-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 K08M4_RS09800 2b9e3c8654d60e2e6da2d6ef50f4a7b1 335 SUPERFAMILY SSF52540 51 195 1.91E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09800 2b9e3c8654d60e2e6da2d6ef50f4a7b1 335 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 23 325 2.3E-91 T 05-07-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 K08M4_RS09800 2b9e3c8654d60e2e6da2d6ef50f4a7b1 335 Gene3D G3DSA:3.40.50.300 49 123 5.3E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS09800 2b9e3c8654d60e2e6da2d6ef50f4a7b1 335 Gene3D G3DSA:3.40.50.300 190 199 5.3E-5 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15755 a734d456aa15dcce0e7cece732474a87 275 SUPERFAMILY SSF53474 9 274 7.36E-49 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS15755 a734d456aa15dcce0e7cece732474a87 275 Gene3D G3DSA:3.40.50.1820 9 274 3.5E-60 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS15755 a734d456aa15dcce0e7cece732474a87 275 Pfam PF00756 Putative esterase 15 266 4.7E-25 T 05-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 K08M4_RS19100 61ef64fc45dc1f138b719650bd4fac7c 272 Pfam PF11060 Protein of unknown function (DUF2861) 21 271 4.3E-73 T 05-07-2017 IPR021290 Protein of unknown function DUF2861 K08M4_RS02615 ea15d41e62897260cf8f8b0da33cdc85 373 SMART SM00382 29 217 4.4E-11 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS02615 ea15d41e62897260cf8f8b0da33cdc85 373 Gene3D G3DSA:2.40.50.140 294 356 3.0E-13 T 05-07-2017 IPR012340 Nucleic acid-binding, OB-fold K08M4_RS02615 ea15d41e62897260cf8f8b0da33cdc85 373 Pfam PF08402 TOBE domain 289 363 6.3E-10 T 05-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 K08M4_RS02615 ea15d41e62897260cf8f8b0da33cdc85 373 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 05-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 K08M4_RS02615 ea15d41e62897260cf8f8b0da33cdc85 373 Gene3D G3DSA:3.40.50.300 4 240 6.0E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02615 ea15d41e62897260cf8f8b0da33cdc85 373 Gene3D G3DSA:2.40.50.100 245 293 2.9E-11 T 05-07-2017 K08M4_RS02615 ea15d41e62897260cf8f8b0da33cdc85 373 Gene3D G3DSA:2.40.50.100 357 371 2.9E-11 T 05-07-2017 K08M4_RS02615 ea15d41e62897260cf8f8b0da33cdc85 373 Pfam PF00005 ABC transporter 21 162 4.1E-29 T 05-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 K08M4_RS02615 ea15d41e62897260cf8f8b0da33cdc85 373 SUPERFAMILY SSF52540 4 249 5.85E-79 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS02615 ea15d41e62897260cf8f8b0da33cdc85 373 SUPERFAMILY SSF50331 242 371 1.14E-26 T 05-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal K08M4_RS10145 6a4e0ce5c659adc09fa9ea2534429e9a 155 Pfam PF11911 Protein of unknown function (DUF3429) 14 153 2.0E-29 T 05-07-2017 IPR021836 Protein of unknown function DUF3429 K08M4_RS02600 8f2a9f7bc4dbc1d936ea1aa717bf37b2 342 Pfam PF16941 Putative cyclodextrin porin 3 342 9.7E-206 T 05-07-2017 IPR031609 Cyclodextrin porin CymA GO:0098657 K08M4_RS02600 8f2a9f7bc4dbc1d936ea1aa717bf37b2 342 SUPERFAMILY SSF56925 177 342 7.32E-5 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS01920 07ca8d8e8044a93d314ce217eaf1297e 164 SUPERFAMILY SSF55729 6 164 4.63E-31 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS01920 07ca8d8e8044a93d314ce217eaf1297e 164 Pfam PF00583 Acetyltransferase (GNAT) family 64 142 1.3E-13 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS01920 07ca8d8e8044a93d314ce217eaf1297e 164 Gene3D G3DSA:3.40.630.30 6 164 2.2E-37 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS18085 288df0cf4c183ed33ca1ce959c97aeed 186 Pfam PF01618 MotA/TolQ/ExbB proton channel family 75 179 1.3E-21 T 05-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 K08M4_RS18240 288df0cf4c183ed33ca1ce959c97aeed 186 Pfam PF01618 MotA/TolQ/ExbB proton channel family 75 179 1.3E-21 T 05-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 K08M4_RS04870 0d34ea1920a060adccb2b59c0f4d952b 348 Pfam PF03116 NQR2, RnfD, RnfE family 6 347 4.3E-105 T 05-07-2017 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 K08M4_RS04870 0d34ea1920a060adccb2b59c0f4d952b 348 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 8 348 2.0E-138 T 05-07-2017 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 K08M4_RS04870 0d34ea1920a060adccb2b59c0f4d952b 348 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 3 348 27.46 T 05-07-2017 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 K08M4_RS08770 26d475cc8f66d8d855ddbc7fbd591c63 126 Gene3D G3DSA:3.10.180.10 6 125 2.3E-28 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS08770 26d475cc8f66d8d855ddbc7fbd591c63 126 SUPERFAMILY SSF54593 4 125 2.61E-17 T 05-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase K08M4_RS08700 84f8bacd3d3607e7e701a59b4a88e3fe 387 Pfam PF06965 Na+/H+ antiporter 1 7 373 1.7E-143 T 05-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 K08M4_RS08700 84f8bacd3d3607e7e701a59b4a88e3fe 387 Gene3D G3DSA:1.20.1530.10 4 378 6.3E-150 T 05-07-2017 IPR023171 Na/H antiporter domain K08M4_RS08700 84f8bacd3d3607e7e701a59b4a88e3fe 387 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 5 382 23.422 T 05-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 K08M4_RS08700 84f8bacd3d3607e7e701a59b4a88e3fe 387 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 8 373 2.9E-182 T 05-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 K08M4_RS10085 c54ce637bd904ba73c46498aaa4bd9ec 199 Pfam PF01810 LysE type translocator 16 196 6.2E-15 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS04325 7f615c98cb63cdb196b87313c9b40131 406 Pfam PF14559 Tetratricopeptide repeat 176 244 3.1E-6 T 05-07-2017 K08M4_RS04325 7f615c98cb63cdb196b87313c9b40131 406 Gene3D G3DSA:1.25.40.10 159 202 1.4E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS04325 7f615c98cb63cdb196b87313c9b40131 406 Gene3D G3DSA:1.25.40.10 203 287 1.4E-18 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS04325 7f615c98cb63cdb196b87313c9b40131 406 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 3 115 4.3E-29 T 05-07-2017 IPR017560 Cytochrome c-type biogenesis protein CcmI K08M4_RS04325 7f615c98cb63cdb196b87313c9b40131 406 SUPERFAMILY SSF48452 161 266 5.52E-14 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS00660 72c6916a9550f92249fab9ff4a39e5f8 221 Pfam PF01902 Diphthamide synthase 4 213 1.4E-26 T 05-07-2017 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 K08M4_RS00660 72c6916a9550f92249fab9ff4a39e5f8 221 SUPERFAMILY SSF52402 1 218 1.21E-56 T 05-07-2017 K08M4_RS00660 72c6916a9550f92249fab9ff4a39e5f8 221 Gene3D G3DSA:3.90.1490.10 146 210 2.8E-14 T 05-07-2017 K08M4_RS00660 72c6916a9550f92249fab9ff4a39e5f8 221 Gene3D G3DSA:3.40.50.620 2 143 7.9E-24 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS11430 cfd1cd7fed96d9d0d1d93ffb8edb3b37 454 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 46 65 9.3E-11 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS11430 cfd1cd7fed96d9d0d1d93ffb8edb3b37 454 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 17 38 9.3E-11 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS11430 cfd1cd7fed96d9d0d1d93ffb8edb3b37 454 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 313 332 9.3E-11 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS11430 cfd1cd7fed96d9d0d1d93ffb8edb3b37 454 SUPERFAMILY SSF161070 9 452 2.62E-118 T 05-07-2017 K08M4_RS11430 cfd1cd7fed96d9d0d1d93ffb8edb3b37 454 Pfam PF00209 Sodium:neurotransmitter symporter family 9 130 3.7E-21 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS11430 cfd1cd7fed96d9d0d1d93ffb8edb3b37 454 Pfam PF00209 Sodium:neurotransmitter symporter family 153 451 2.1E-25 T 05-07-2017 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 K08M4_RS11720 66386f97bd6e181e2539a5e8a1f75c85 119 Pfam PF04355 SmpA / OmlA family 35 102 2.5E-26 T 05-07-2017 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 K08M4_RS11720 66386f97bd6e181e2539a5e8a1f75c85 119 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 7 112 32.672 T 05-07-2017 IPR026592 Outer membrane protein assembly factor BamE K08M4_RS13505 1db34ea68482a83c8fff46ceeb62ac58 62 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 5 59 9.5E-24 T 05-07-2017 IPR019201 Protein of unknown function DUF2065 K08M4_RS00530 425d1a20f17408a055918275c115d997 206 Pfam PF07947 YhhN-like protein 26 204 1.3E-33 T 05-07-2017 IPR012506 YhhN-like GO:0016021 K08M4_RS15910 23bcf776bd78e52c1db9280f8477d3a1 131 PIRSF PIRSF028770 1 128 6.3E-68 T 05-07-2017 IPR011223 Uncharacterised conserved protein UCP028770 K08M4_RS15910 23bcf776bd78e52c1db9280f8477d3a1 131 Pfam PF11742 Protein of unknown function (DUF3302) 3 78 9.2E-41 T 05-07-2017 IPR011223 Uncharacterised conserved protein UCP028770 K08M4_RS18355 36251580db4a1fd1365dfe2396f48d6b 341 Pfam PF12833 Helix-turn-helix domain 263 338 3.6E-19 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS18355 36251580db4a1fd1365dfe2396f48d6b 341 Gene3D G3DSA:1.10.10.60 290 339 8.7E-15 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS18355 36251580db4a1fd1365dfe2396f48d6b 341 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 321 337 7.0E-6 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS18355 36251580db4a1fd1365dfe2396f48d6b 341 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 306 321 7.0E-6 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS18355 36251580db4a1fd1365dfe2396f48d6b 341 SMART SM00342 255 337 1.5E-22 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS18355 36251580db4a1fd1365dfe2396f48d6b 341 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 32 212 2.7E-35 T 05-07-2017 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal K08M4_RS18355 36251580db4a1fd1365dfe2396f48d6b 341 SUPERFAMILY SSF46689 290 339 2.46E-12 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS11265 09036132828ae9c95f417027dfb41a28 102 Pfam PF11743 Protein of unknown function (DUF3301) 6 99 1.8E-30 T 05-07-2017 IPR021732 Protein of unknown function DUF3301 K08M4_RS11730 5570a1ec0cefb05286e5898ebdb5fc0e 142 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 135 2.3E-30 T 05-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain K08M4_RS11730 5570a1ec0cefb05286e5898ebdb5fc0e 142 SUPERFAMILY SSF55961 1 142 8.89E-34 T 05-07-2017 K08M4_RS11730 5570a1ec0cefb05286e5898ebdb5fc0e 142 Gene3D G3DSA:3.30.530.20 1 142 2.1E-46 T 05-07-2017 IPR023393 START-like domain K08M4_RS07360 695312c77c362df6ebbea451fb9fc24d 134 SUPERFAMILY SSF47226 20 125 4.45E-21 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS07360 695312c77c362df6ebbea451fb9fc24d 134 Gene3D G3DSA:1.20.120.160 16 126 8.5E-24 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS07360 695312c77c362df6ebbea451fb9fc24d 134 Pfam PF01627 Hpt domain 43 119 1.4E-8 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS10045 8937319b7fb02e942467dfc025c9d8bd 458 Pfam PF00188 Cysteine-rich secretory protein family 347 457 1.5E-9 T 05-07-2017 IPR014044 CAP domain K08M4_RS10045 8937319b7fb02e942467dfc025c9d8bd 458 SUPERFAMILY SSF55797 323 458 4.45E-8 T 05-07-2017 IPR014044 CAP domain K08M4_RS10045 8937319b7fb02e942467dfc025c9d8bd 458 Gene3D G3DSA:3.40.33.10 322 456 6.1E-4 T 05-07-2017 IPR014044 CAP domain K08M4_RS07500 0592c8bd22b9fe7c3fa5819335f9aeae 781 Pfam PF13401 AAA domain 471 582 5.5E-7 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS07500 0592c8bd22b9fe7c3fa5819335f9aeae 781 Gene3D G3DSA:3.40.50.300 458 584 1.0E-6 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07500 0592c8bd22b9fe7c3fa5819335f9aeae 781 SUPERFAMILY SSF52540 457 630 1.52E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06430 122319babaa0713dcb886cae3059cf59 300 Gene3D G3DSA:3.60.15.10 37 256 3.2E-34 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS06430 122319babaa0713dcb886cae3059cf59 300 SMART SM00849 49 231 1.7E-17 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS06430 122319babaa0713dcb886cae3059cf59 300 SUPERFAMILY SSF56281 32 255 2.03E-39 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS06430 122319babaa0713dcb886cae3059cf59 300 Pfam PF00753 Metallo-beta-lactamase superfamily 49 231 1.1E-8 T 05-07-2017 IPR001279 Metallo-beta-lactamase K08M4_RS07025 e660a1ff48c2db59d8473c0707028011 133 Pfam PF03692 Putative zinc- or iron-chelating domain 3 96 6.4E-7 T 05-07-2017 IPR005358 Putative zinc- or iron-chelating domain containing protein K08M4_RS20755 1edb92bdafdda20f057af4f67245203e 248 SUPERFAMILY SSF48317 38 117 2.35E-21 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase K08M4_RS20755 1edb92bdafdda20f057af4f67245203e 248 SUPERFAMILY SSF48317 147 236 2.35E-21 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase K08M4_RS20755 1edb92bdafdda20f057af4f67245203e 248 SMART SM00014 81 229 2.1E-12 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase K08M4_RS20755 1edb92bdafdda20f057af4f67245203e 248 Gene3D G3DSA:1.20.144.10 56 231 2.3E-20 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase K08M4_RS20755 1edb92bdafdda20f057af4f67245203e 248 Pfam PF01569 PAP2 superfamily 84 233 2.5E-18 T 05-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase K08M4_RS02690 43f576563c08b1e64cb6a34d71699a93 85 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 6 83 5.8E-21 T 05-07-2017 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 K08M4_RS02690 43f576563c08b1e64cb6a34d71699a93 85 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 10 80 8.1E-21 T 05-07-2017 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 K08M4_RS02690 43f576563c08b1e64cb6a34d71699a93 85 Hamap MF_00404 Probable oxaloacetate decarboxylase gamma chain [oadG]. 1 85 37.28 T 05-07-2017 IPR023424 Oxaloacetate decarboxylase gamma chain, probable GO:0008948 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 K08M4_RS09860 d0adb622da3100a78b365dadaf8c9ed9 179 Hamap MF_01047 UPF0227 protein YcfP [ycfP]. 1 178 48.001 T 05-07-2017 IPR022987 Uncharacterised protein family UPF0227 K08M4_RS09860 d0adb622da3100a78b365dadaf8c9ed9 179 SUPERFAMILY SSF53474 2 176 1.74E-6 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS09860 d0adb622da3100a78b365dadaf8c9ed9 179 Pfam PF05728 Uncharacterised protein family (UPF0227) 1 177 8.3E-68 T 05-07-2017 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA K08M4_RS05455 6a93f5506ed0ff74ff65e45e0629e7d0 268 Pfam PF02698 DUF218 domain 80 242 5.9E-27 T 05-07-2017 IPR003848 Domain of unknown function DUF218 K08M4_RS05455 6a93f5506ed0ff74ff65e45e0629e7d0 268 Gene3D G3DSA:3.40.50.620 78 210 7.4E-15 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS19385 003abe73edfdd97a5794882b1b441c70 331 Gene3D G3DSA:3.20.20.140 2 323 2.1E-76 T 05-07-2017 K08M4_RS19385 003abe73edfdd97a5794882b1b441c70 331 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 17 322 5.1E-71 T 05-07-2017 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 K08M4_RS19385 003abe73edfdd97a5794882b1b441c70 331 SUPERFAMILY SSF51556 4 246 9.41E-81 T 05-07-2017 IPR032466 Metal-dependent hydrolase K08M4_RS19385 003abe73edfdd97a5794882b1b441c70 331 SUPERFAMILY SSF51556 277 325 9.41E-81 T 05-07-2017 IPR032466 Metal-dependent hydrolase K08M4_RS06880 2cbac824630bea3eef857e2fb0eeef21 335 SUPERFAMILY SSF161111 15 148 1.27E-48 T 05-07-2017 K08M4_RS06880 2cbac824630bea3eef857e2fb0eeef21 335 SUPERFAMILY SSF161111 188 256 1.27E-48 T 05-07-2017 K08M4_RS06880 2cbac824630bea3eef857e2fb0eeef21 335 Pfam PF01545 Cation efflux family 23 255 4.0E-38 T 05-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 K08M4_RS06880 2cbac824630bea3eef857e2fb0eeef21 335 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 327 6.9E-66 T 05-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 K08M4_RS06880 2cbac824630bea3eef857e2fb0eeef21 335 Gene3D G3DSA:1.20.1510.10 19 148 5.9E-51 T 05-07-2017 IPR027469 Cation efflux protein transmembrane domain K08M4_RS06880 2cbac824630bea3eef857e2fb0eeef21 335 Gene3D G3DSA:1.20.1510.10 188 255 5.9E-51 T 05-07-2017 IPR027469 Cation efflux protein transmembrane domain K08M4_RS03395 aa1dbd63459bba059e447efbd798780a 323 Pfam PF00482 Type II secretion system (T2SS), protein F 177 305 1.6E-22 T 05-07-2017 IPR018076 Type II secretion system F domain K08M4_RS15785 6461836e4d7b806cf3af7d9ec8e48df2 112 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 7 99 1.8E-7 T 05-07-2017 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family K08M4_RS16935 3c4df0de5c2a78d56f574f4091ebfbae 440 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 17 435 1.5E-77 T 05-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit K08M4_RS16935 3c4df0de5c2a78d56f574f4091ebfbae 440 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 27 438 3.6E-86 T 05-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 K08M4_RS16935 3c4df0de5c2a78d56f574f4091ebfbae 440 PIRSF PIRSF006066 12 440 3.0E-69 T 05-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 K08M4_RS05290 9acf1d80b910355d10d117c80e73bb61 911 SMART SM01276 457 782 6.9E-36 T 05-07-2017 IPR031161 Peptidase family M60 domain K08M4_RS05290 9acf1d80b910355d10d117c80e73bb61 911 Pfam PF13402 Peptidase M60, enhancin and enhancin-like 450 859 3.4E-11 T 05-07-2017 IPR031161 Peptidase family M60 domain K08M4_RS03820 bb0e34dfa198996ce132c99fb8630552 127 Pfam PF04247 Invasion gene expression up-regulator, SirB 2 123 1.0E-38 T 05-07-2017 IPR007360 Invasion gene expression up-regulator, SirB K08M4_RS03820 bb0e34dfa198996ce132c99fb8630552 127 PIRSF PIRSF005610 1 121 1.1E-16 T 05-07-2017 IPR007360 Invasion gene expression up-regulator, SirB K08M4_RS12030 679c294cf866417adf95484c86a051a1 325 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 19 310 4.8E-73 T 05-07-2017 IPR011862 Phosphate binding protein GO:0006810 K08M4_RS12030 679c294cf866417adf95484c86a051a1 325 SUPERFAMILY SSF53850 40 322 1.13E-65 T 05-07-2017 K08M4_RS12030 679c294cf866417adf95484c86a051a1 325 Gene3D G3DSA:3.40.190.10 126 268 3.3E-33 T 05-07-2017 K08M4_RS12030 679c294cf866417adf95484c86a051a1 325 Gene3D G3DSA:3.40.190.10 269 318 2.0E-6 T 05-07-2017 K08M4_RS12030 679c294cf866417adf95484c86a051a1 325 Gene3D G3DSA:3.40.190.10 45 123 2.0E-6 T 05-07-2017 K08M4_RS12030 679c294cf866417adf95484c86a051a1 325 Pfam PF12849 PBP superfamily domain 42 297 8.5E-27 T 05-07-2017 IPR024370 PBP domain K08M4_RS06400 b72b96f1f9a2ab0f0ed1fe7cecd2a606 238 Pfam PF08856 Protein of unknown function (DUF1826) 38 236 5.4E-67 T 05-07-2017 IPR014955 Protein of unknown function DUF1826 K08M4_RS21470 ed5b529b7673bf4c85fccea9e7869cc4 160 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 4 71 3.5E-4 T 05-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 K08M4_RS21470 ed5b529b7673bf4c85fccea9e7869cc4 160 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 126 132 - T 05-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 K08M4_RS21470 ed5b529b7673bf4c85fccea9e7869cc4 160 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 76 155 2.7E-38 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 K08M4_RS21470 ed5b529b7673bf4c85fccea9e7869cc4 160 SUPERFAMILY SSF53155 5 80 2.94E-18 T 05-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 K08M4_RS21470 ed5b529b7673bf4c85fccea9e7869cc4 160 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 3 158 37.597 T 05-07-2017 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 K08M4_RS21470 ed5b529b7673bf4c85fccea9e7869cc4 160 SUPERFAMILY SSF46767 75 156 1.57E-33 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 K08M4_RS21470 ed5b529b7673bf4c85fccea9e7869cc4 160 Gene3D G3DSA:1.10.10.10 74 157 9.5E-36 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS21470 ed5b529b7673bf4c85fccea9e7869cc4 160 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 77 156 4.0E-33 T 05-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 K08M4_RS12480 9e3c2e4520b96326bfd635bf0427bf2e 142 Pfam PF07386 Protein of unknown function (DUF1499) 30 135 1.1E-21 T 05-07-2017 IPR010865 Protein of unknown function DUF1499 K08M4_RS12480 9e3c2e4520b96326bfd635bf0427bf2e 142 PIRSF PIRSF026426 1 142 1.6E-47 T 05-07-2017 IPR010865 Protein of unknown function DUF1499 K08M4_RS02790 2667be575f32e2074e69a77836f65408 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 372 386 3.1E-19 T 05-07-2017 IPR003004 GspF/PilC family K08M4_RS02790 2667be575f32e2074e69a77836f65408 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 168 196 3.1E-19 T 05-07-2017 IPR003004 GspF/PilC family K08M4_RS02790 2667be575f32e2074e69a77836f65408 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 388 407 3.1E-19 T 05-07-2017 IPR003004 GspF/PilC family K08M4_RS02790 2667be575f32e2074e69a77836f65408 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 69 81 3.1E-19 T 05-07-2017 IPR003004 GspF/PilC family K08M4_RS02790 2667be575f32e2074e69a77836f65408 408 Pfam PF00482 Type II secretion system (T2SS), protein F 74 196 2.4E-31 T 05-07-2017 IPR018076 Type II secretion system F domain K08M4_RS02790 2667be575f32e2074e69a77836f65408 408 Pfam PF00482 Type II secretion system (T2SS), protein F 277 399 5.7E-26 T 05-07-2017 IPR018076 Type II secretion system F domain K08M4_RS02790 2667be575f32e2074e69a77836f65408 408 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 168 196 - T 05-07-2017 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 K08M4_RS05810 ddc4f60a2cab1bb82dc6cf42f40fc85e 566 SUPERFAMILY SSF161098 5 274 2.29E-24 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS05810 ddc4f60a2cab1bb82dc6cf42f40fc85e 566 SUPERFAMILY SSF161098 300 537 2.09E-24 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS05810 ddc4f60a2cab1bb82dc6cf42f40fc85e 566 Gene3D G3DSA:1.10.3720.10 299 541 2.1E-19 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS05810 ddc4f60a2cab1bb82dc6cf42f40fc85e 566 Gene3D G3DSA:1.10.3720.10 5 276 1.4E-22 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS19935 bea564eca245da435abba7f0c1093fd9 121 Pfam PF10761 Protein of unknown function (DUF2590) 16 114 8.2E-32 T 05-07-2017 IPR019697 Bacteriophage HP1, Orf28 K08M4_RS00620 3e62a65c9dda29e0a94e0c096be88992 434 TIGRFAM TIGR00797 matE: MATE efflux family protein 11 405 2.3E-72 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS00620 3e62a65c9dda29e0a94e0c096be88992 434 Pfam PF01554 MatE 237 386 4.3E-16 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS00620 3e62a65c9dda29e0a94e0c096be88992 434 Pfam PF01554 MatE 11 171 1.4E-24 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS18855 dfb2754d137a7eb6bb8d37846d7dd9fa 245 SMART SM00052 6 239 6.9E-12 T 05-07-2017 IPR001633 EAL domain K08M4_RS18855 dfb2754d137a7eb6bb8d37846d7dd9fa 245 Gene3D G3DSA:3.20.20.450 11 237 5.9E-41 T 05-07-2017 IPR001633 EAL domain K08M4_RS18855 dfb2754d137a7eb6bb8d37846d7dd9fa 245 SUPERFAMILY SSF141868 12 238 3.53E-43 T 05-07-2017 IPR001633 EAL domain K08M4_RS18855 dfb2754d137a7eb6bb8d37846d7dd9fa 245 Pfam PF00563 EAL domain 11 234 1.9E-45 T 05-07-2017 IPR001633 EAL domain K08M4_RS05630 263f068a6c399f686f26e2e825c6534a 189 SUPERFAMILY SSF101327 2 176 1.31E-30 T 05-07-2017 IPR011978 Uncharacterised protein family UPF0149 K08M4_RS05630 263f068a6c399f686f26e2e825c6534a 189 Pfam PF03695 Uncharacterised protein family (UPF0149) 3 178 2.2E-34 T 05-07-2017 IPR011978 Uncharacterised protein family UPF0149 K08M4_RS05630 263f068a6c399f686f26e2e825c6534a 189 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 2 174 2.3E-42 T 05-07-2017 IPR011978 Uncharacterised protein family UPF0149 K08M4_RS12050 1b637a38af0ba982b3c1d6aa3f195929 472 Pfam PF01136 Peptidase family U32 80 361 2.5E-96 T 05-07-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 K08M4_RS12050 1b637a38af0ba982b3c1d6aa3f195929 472 ProSitePatterns PS01276 Peptidase family U32 signature. 167 185 - T 05-07-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 K08M4_RS12050 1b637a38af0ba982b3c1d6aa3f195929 472 Pfam PF16325 Peptidase family U32 C-terminal domain 377 458 3.0E-19 T 05-07-2017 IPR032525 Peptidase family U32, C-terminal K08M4_RS16195 102a9497d7c371f74a86bd5330da7527 293 SUPERFAMILY SSF103481 221 292 1.29E-5 T 05-07-2017 K08M4_RS16195 102a9497d7c371f74a86bd5330da7527 293 SUPERFAMILY SSF103481 39 145 1.1E-7 T 05-07-2017 K08M4_RS10365 967b24a0d59ce4716536d0da5fd9ae19 99 Gene3D G3DSA:1.10.150.280 36 98 1.6E-17 T 05-07-2017 K08M4_RS10365 967b24a0d59ce4716536d0da5fd9ae19 99 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 36 98 1.1E-24 T 05-07-2017 IPR004509 Competence protein ComEA, helix-hairpin-helix domain K08M4_RS10365 967b24a0d59ce4716536d0da5fd9ae19 99 SUPERFAMILY SSF47781 33 98 8.56E-25 T 05-07-2017 IPR010994 RuvA domain 2-like K08M4_RS10365 967b24a0d59ce4716536d0da5fd9ae19 99 Pfam PF12836 Helix-hairpin-helix motif 37 97 2.4E-21 T 05-07-2017 K08M4_RS04050 69e2b817fa094b0aa763217cfa08fd1e 236 Pfam PF13860 FlgD Ig-like domain 117 185 1.7E-19 T 05-07-2017 IPR025965 FlgD Ig-like domain K08M4_RS04050 69e2b817fa094b0aa763217cfa08fd1e 236 Pfam PF13861 FlgD Tudor-like domain 94 230 4.1E-15 T 05-07-2017 IPR025963 FlgD Tudor-like domain K08M4_RS04050 69e2b817fa094b0aa763217cfa08fd1e 236 Pfam PF03963 Flagellar hook capping protein - N-terminal region 21 85 5.5E-22 T 05-07-2017 IPR005648 Flagellar hook capping protein K08M4_RS08705 593cfe6c571b65c8d0da3c5c7d95e87b 382 Pfam PF07143 CrtC N-terminal lipocalin domain 87 256 4.8E-45 T 05-07-2017 IPR010791 AttH domain K08M4_RS08705 593cfe6c571b65c8d0da3c5c7d95e87b 382 Gene3D G3DSA:2.40.370.10 75 258 5.0E-60 T 05-07-2017 IPR023374 AttH-like domain K08M4_RS08705 593cfe6c571b65c8d0da3c5c7d95e87b 382 SUPERFAMILY SSF159245 64 382 1.44E-96 T 05-07-2017 K08M4_RS08705 593cfe6c571b65c8d0da3c5c7d95e87b 382 Gene3D G3DSA:2.40.370.10 262 382 8.2E-36 T 05-07-2017 IPR023374 AttH-like domain K08M4_RS08705 593cfe6c571b65c8d0da3c5c7d95e87b 382 Pfam PF17186 Lipocalin-like domain 262 382 1.6E-32 T 05-07-2017 IPR033451 AttH, lipocalin-like domain K08M4_RS16900 ecc76b564fecf4ab534ea88d5bc0286f 473 SUPERFAMILY SSF51905 184 311 1.18E-37 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS16900 ecc76b564fecf4ab534ea88d5bc0286f 473 SUPERFAMILY SSF51905 28 130 1.18E-37 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS16900 ecc76b564fecf4ab534ea88d5bc0286f 473 Pfam PF01266 FAD dependent oxidoreductase 37 399 6.0E-47 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 K08M4_RS16900 ecc76b564fecf4ab534ea88d5bc0286f 473 TIGRFAM TIGR03329 Phn_aa_oxid: putative aminophosphonate oxidoreductase 6 470 8.2E-226 T 05-07-2017 IPR017715 Putative aminophosphonate oxidoreductase K08M4_RS16900 ecc76b564fecf4ab534ea88d5bc0286f 473 Gene3D G3DSA:3.50.50.60 180 259 5.1E-45 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS16900 ecc76b564fecf4ab534ea88d5bc0286f 473 Gene3D G3DSA:3.50.50.60 28 127 5.1E-45 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS16900 ecc76b564fecf4ab534ea88d5bc0286f 473 Gene3D G3DSA:3.50.50.60 361 408 5.1E-45 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS10415 65796ff54f6852d8bed136570cc857c3 251 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 43 194 7.5E-26 T 05-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component K08M4_RS15570 dcf1b29b47bace197a1b81e0704b11af 143 Pfam PF05232 Chlorhexidine efflux transporter 1 62 2.3E-20 T 05-07-2017 IPR007896 Chlorhexidine efflux transporter K08M4_RS15570 dcf1b29b47bace197a1b81e0704b11af 143 Pfam PF05232 Chlorhexidine efflux transporter 69 130 1.5E-21 T 05-07-2017 IPR007896 Chlorhexidine efflux transporter K08M4_RS14200 e3918d746ccd856341384cd8451e857b 162 Pfam PF04612 Type II secretion system (T2SS), protein M 6 161 3.5E-56 T 05-07-2017 IPR007690 Type II secretion system, protein M GO:0006858 K08M4_RS14200 e3918d746ccd856341384cd8451e857b 162 PIRSF PIRSF006291 2 161 6.5E-39 T 05-07-2017 IPR007690 Type II secretion system, protein M GO:0006858 K08M4_RS14200 e3918d746ccd856341384cd8451e857b 162 SUPERFAMILY SSF103054 84 161 2.22E-24 T 05-07-2017 IPR023229 Type II secretion system protein M, periplasmic domain K08M4_RS14200 e3918d746ccd856341384cd8451e857b 162 Gene3D G3DSA:3.30.1360.100 84 162 2.5E-33 T 05-07-2017 IPR023229 Type II secretion system protein M, periplasmic domain K08M4_RS16920 b07281bb4749883f89fa2092369fbbcd 300 TIGRFAM TIGR03340 phn_DUF6: phosphonate utilization associated putative membrane protein 5 297 6.6E-93 T 05-07-2017 IPR017725 Phosphonate utilization associated transmembrane protein, putative K08M4_RS16920 b07281bb4749883f89fa2092369fbbcd 300 SUPERFAMILY SSF103481 40 139 1.44E-7 T 05-07-2017 K08M4_RS16920 b07281bb4749883f89fa2092369fbbcd 300 Pfam PF00892 EamA-like transporter family 152 299 1.8E-6 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS16920 b07281bb4749883f89fa2092369fbbcd 300 SUPERFAMILY SSF103481 205 298 1.7E-7 T 05-07-2017 K08M4_RS13185 223546865557044e170c8d9eb545275c 215 Pfam PF04350 Pilus assembly protein, PilO 70 179 6.4E-7 T 05-07-2017 IPR007445 Pilus assembly protein, PilO K08M4_RS13185 223546865557044e170c8d9eb545275c 215 Gene3D G3DSA:3.30.70.60 111 191 6.6E-6 T 05-07-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 K08M4_RS06765 c345a354db7b634a5b08d26d9156b1ce 145 SUPERFAMILY SSF53098 4 139 7.84E-21 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS06765 c345a354db7b634a5b08d26d9156b1ce 145 Gene3D G3DSA:3.30.420.10 5 128 4.0E-20 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS06765 c345a354db7b634a5b08d26d9156b1ce 145 Pfam PF00075 RNase H 4 126 6.0E-15 T 05-07-2017 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 K08M4_RS20625 9d32ad5a043a66c004cf8d6bb86a2568 427 SUPERFAMILY SSF56349 125 408 1.27E-36 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS20625 9d32ad5a043a66c004cf8d6bb86a2568 427 Gene3D G3DSA:1.10.443.10 228 408 2.1E-21 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS20625 9d32ad5a043a66c004cf8d6bb86a2568 427 Pfam PF00589 Phage integrase family 254 408 3.8E-12 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS20625 9d32ad5a043a66c004cf8d6bb86a2568 427 Gene3D G3DSA:1.10.150.130 125 213 1.0E-8 T 05-07-2017 IPR023109 Integrase/recombinase, N-terminal K08M4_RS04740 0c78bc314e776e5bd819e0199a0a9aa6 147 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 3.7E-31 T 05-07-2017 IPR000944 Transcription regulator Rrf2-type K08M4_RS04740 0c78bc314e776e5bd819e0199a0a9aa6 147 Gene3D G3DSA:1.10.10.10 1 132 3.9E-42 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS04740 0c78bc314e776e5bd819e0199a0a9aa6 147 Pfam PF02082 Transcriptional regulator 1 81 7.4E-20 T 05-07-2017 IPR000944 Transcription regulator Rrf2-type K08M4_RS04740 0c78bc314e776e5bd819e0199a0a9aa6 147 SUPERFAMILY SSF46785 3 132 2.35E-33 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS13130 12de9a23cb6ebedd19803cfeefa251c1 184 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 35 3.4E-6 T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS13130 12de9a23cb6ebedd19803cfeefa251c1 184 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 14 34 - T 05-07-2017 IPR012902 Prokaryotic N-terminal methylation site K08M4_RS14520 39d3c640549123ea57343c9142a2d4ce 175 Gene3D G3DSA:1.20.1260.10 1 162 2.7E-62 T 05-07-2017 IPR012347 Ferritin-related K08M4_RS14520 39d3c640549123ea57343c9142a2d4ce 175 SUPERFAMILY SSF47240 1 159 2.85E-58 T 05-07-2017 IPR009078 Ferritin-like superfamily K08M4_RS14520 39d3c640549123ea57343c9142a2d4ce 175 Pfam PF00210 Ferritin-like domain 8 143 2.6E-39 T 05-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 K08M4_RS03865 3432500ac3e04379997b596b840947fe 295 Pfam PF01963 TraB family 25 278 3.5E-51 T 05-07-2017 IPR002816 Pheromone shutdown, TraB K08M4_RS19735 1e887c9b0623b0c5851545b2044861a8 335 SMART SM00342 245 326 1.4E-13 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS19735 1e887c9b0623b0c5851545b2044861a8 335 SUPERFAMILY SSF46689 285 329 2.83E-9 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS19735 1e887c9b0623b0c5851545b2044861a8 335 Pfam PF12833 Helix-turn-helix domain 252 327 3.2E-12 T 05-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 K08M4_RS19735 1e887c9b0623b0c5851545b2044861a8 335 Gene3D G3DSA:1.10.10.60 286 328 2.5E-11 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS19735 1e887c9b0623b0c5851545b2044861a8 335 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 310 326 4.2E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS19735 1e887c9b0623b0c5851545b2044861a8 335 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 295 310 4.2E-5 T 05-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 K08M4_RS02500 4101bb89d14f22e03a28eede685ac615 271 SUPERFAMILY SSF101386 138 239 3.55E-23 T 05-07-2017 K08M4_RS02500 4101bb89d14f22e03a28eede685ac615 271 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 171 231 2.9E-6 T 05-07-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core K08M4_RS02500 4101bb89d14f22e03a28eede685ac615 271 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 28 101 3.5E-27 T 05-07-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core K08M4_RS02500 4101bb89d14f22e03a28eede685ac615 271 TIGRFAM TIGR00444 mazG: MazG family protein 11 260 2.7E-101 T 05-07-2017 IPR011551 NTP pyrophosphohydrolase MazG K08M4_RS02500 4101bb89d14f22e03a28eede685ac615 271 SUPERFAMILY SSF101386 3 104 3.11E-24 T 05-07-2017 K08M4_RS02500 4101bb89d14f22e03a28eede685ac615 271 Gene3D G3DSA:1.10.287.1080 134 222 3.9E-12 T 05-07-2017 K08M4_RS02500 4101bb89d14f22e03a28eede685ac615 271 Gene3D G3DSA:1.10.287.1080 9 72 3.4E-7 T 05-07-2017 K08M4_RS00615 8c6de4ddd7534851df066ce17de9a044 292 Pfam PF04072 Leucine carboxyl methyltransferase 86 151 2.7E-7 T 05-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 K08M4_RS00615 8c6de4ddd7534851df066ce17de9a044 292 Gene3D G3DSA:3.40.50.150 36 279 5.7E-35 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS00615 8c6de4ddd7534851df066ce17de9a044 292 SUPERFAMILY SSF53335 40 272 1.94E-33 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS00615 8c6de4ddd7534851df066ce17de9a044 292 PIRSF PIRSF028177 25 292 5.1E-69 T 05-07-2017 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 K08M4_RS01255 834f9c315155ec8065f7e3a29992c2e1 341 PIRSF PIRSF019169 1 331 4.9E-80 T 05-07-2017 IPR005883 Type IV pilus assembly protein PilM K08M4_RS01255 834f9c315155ec8065f7e3a29992c2e1 341 Pfam PF11104 Type IV pilus assembly protein PilM; 241 328 2.2E-8 T 05-07-2017 IPR005883 Type IV pilus assembly protein PilM K08M4_RS01255 834f9c315155ec8065f7e3a29992c2e1 341 Pfam PF11104 Type IV pilus assembly protein PilM; 8 220 1.5E-33 T 05-07-2017 IPR005883 Type IV pilus assembly protein PilM K08M4_RS01255 834f9c315155ec8065f7e3a29992c2e1 341 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 3 329 3.7E-80 T 05-07-2017 IPR005883 Type IV pilus assembly protein PilM K08M4_RS01640 328a4e0ca2e87e69b5483a1127ec0f3d 249 Pfam PF05742 Transport and Golgi organisation 2 15 124 7.2E-7 T 05-07-2017 IPR008551 Transport and Golgi organisation protein 2 K08M4_RS04935 c566a8fec84035bd283cea5de2f0851c 81 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 81 1.3E-19 T 05-07-2017 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 K08M4_RS04935 c566a8fec84035bd283cea5de2f0851c 81 Pfam PF02597 ThiS family 4 81 5.4E-22 T 05-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 K08M4_RS04935 c566a8fec84035bd283cea5de2f0851c 81 Gene3D G3DSA:3.10.20.30 1 81 1.9E-24 T 05-07-2017 IPR012675 Beta-grasp domain K08M4_RS04935 c566a8fec84035bd283cea5de2f0851c 81 SUPERFAMILY SSF54285 1 81 2.8E-21 T 05-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp K08M4_RS10125 825313f83a664a9ae0199c6c527580e1 185 Pfam PF07273 Protein of unknown function (DUF1439) 26 177 3.9E-39 T 05-07-2017 IPR010835 Protein of unknown function DUF1439 K08M4_RS01730 3749fb3acb12447bee4036b2b871244a 570 Gene3D G3DSA:2.40.160.50 278 567 1.3E-21 T 05-07-2017 K08M4_RS01730 3749fb3acb12447bee4036b2b871244a 570 Pfam PF01103 Surface antigen 274 567 7.7E-31 T 05-07-2017 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020 K08M4_RS09195 30a0932d28533de8b4eaf27fe8aed97a 255 Gene3D G3DSA:3.30.460.10 34 126 3.6E-9 T 05-07-2017 K08M4_RS09195 30a0932d28533de8b4eaf27fe8aed97a 255 SUPERFAMILY SSF81301 36 81 6.18E-7 T 05-07-2017 K08M4_RS11035 b6012a873a93891d22537e32a161a73a 116 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 3 116 1.1E-44 T 05-07-2017 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 K08M4_RS11035 b6012a873a93891d22537e32a161a73a 116 SUPERFAMILY SSF52833 2 116 1.24E-33 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS11035 b6012a873a93891d22537e32a161a73a 116 Pfam PF03960 ArsC family 6 115 4.7E-17 T 05-07-2017 IPR006660 Arsenate reductase-like K08M4_RS11035 b6012a873a93891d22537e32a161a73a 116 Gene3D G3DSA:3.40.30.10 1 116 8.2E-47 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS20545 a7290bb0c4ce32e5f169a2672cda41a6 160 Pfam PF00583 Acetyltransferase (GNAT) family 62 147 3.0E-10 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS20545 a7290bb0c4ce32e5f169a2672cda41a6 160 SUPERFAMILY SSF55729 1 154 2.52E-25 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS20545 a7290bb0c4ce32e5f169a2672cda41a6 160 Gene3D G3DSA:3.40.630.30 1 156 8.0E-26 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS21530 b77349c5277e281bde7d5a89ec4f40b6 118 Gene3D G3DSA:1.20.1250.10 2 53 9.2E-4 T 05-07-2017 IPR012351 Four-helical cytokine, core K08M4_RS21530 b77349c5277e281bde7d5a89ec4f40b6 118 Pfam PF10928 Protein of unknown function (DUF2810) 65 116 1.9E-32 T 05-07-2017 IPR021230 Protein of unknown function DUF2810 K08M4_RS06065 7602b2ca1f8639b4dde1c5a08294b285 247 Pfam PF07070 SpoOM protein 2 215 7.4E-59 T 05-07-2017 IPR009776 Sporulation stage 0, protein M K08M4_RS20940 f403486640287c95ad5b0f9f47f7a3c5 387 Pfam PF03222 Tryptophan/tyrosine permease family 2 382 1.1E-67 T 05-07-2017 IPR018227 Tryptophan/tyrosine permease GO:0003333 K08M4_RS20940 f403486640287c95ad5b0f9f47f7a3c5 387 PRINTS PR00166 Aromatic amino acid permease signature 35 54 4.3E-26 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS20940 f403486640287c95ad5b0f9f47f7a3c5 387 PRINTS PR00166 Aromatic amino acid permease signature 325 344 4.3E-26 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS20940 f403486640287c95ad5b0f9f47f7a3c5 387 PRINTS PR00166 Aromatic amino acid permease signature 145 165 4.3E-26 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS20940 f403486640287c95ad5b0f9f47f7a3c5 387 PRINTS PR00166 Aromatic amino acid permease signature 304 322 4.3E-26 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS20940 f403486640287c95ad5b0f9f47f7a3c5 387 PRINTS PR00166 Aromatic amino acid permease signature 180 202 4.3E-26 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS20940 f403486640287c95ad5b0f9f47f7a3c5 387 PRINTS PR00166 Aromatic amino acid permease signature 8 31 4.3E-26 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS20940 f403486640287c95ad5b0f9f47f7a3c5 387 PRINTS PR00166 Aromatic amino acid permease signature 80 100 4.3E-26 T 05-07-2017 IPR002091 Aromatic amino acid permease GO:0006865|GO:0016020 K08M4_RS16510 773e6297416221968c5584dc7b40085f 402 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 399 2.1E-139 T 05-07-2017 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 K08M4_RS16510 773e6297416221968c5584dc7b40085f 402 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 9.2E-24 T 05-07-2017 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 K08M4_RS16510 773e6297416221968c5584dc7b40085f 402 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 399 1.9E-71 T 05-07-2017 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 K08M4_RS16510 773e6297416221968c5584dc7b40085f 402 Pfam PF07670 Nucleoside recognition 90 185 2.3E-8 T 05-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 K08M4_RS02340 15e86ca4fa2dae3c4c5d5e60ed67e7a3 209 Pfam PF01810 LysE type translocator 15 201 5.6E-40 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS18490 106d226f9e88016df192584bb2ec0195 122 Pfam PF10719 Late competence development protein ComFB 8 82 1.5E-11 T 05-07-2017 IPR019657 Late competence development protein ComFB K08M4_RS04270 80837e059c7bbb4643298aea382b6076 380 SMART SM00260 233 367 9.8E-5 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS04270 80837e059c7bbb4643298aea382b6076 380 Pfam PF01584 CheW-like domain 237 368 2.0E-13 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS04270 80837e059c7bbb4643298aea382b6076 380 SUPERFAMILY SSF50341 233 369 1.23E-13 T 05-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 K08M4_RS04270 80837e059c7bbb4643298aea382b6076 380 PIRSF PIRSF020479 12 380 1.9E-117 T 05-07-2017 IPR014506 Uncharacterised conserved protein UCP020479, signal transduction CheW-like K08M4_RS17130 02dd01981aedf7863d870b906d59dcbb 144 Pfam PF03733 Inner membrane component domain 4 54 9.1E-15 T 05-07-2017 IPR005185 Inner membrane component domain K08M4_RS17130 02dd01981aedf7863d870b906d59dcbb 144 Pfam PF03733 Inner membrane component domain 76 126 1.7E-18 T 05-07-2017 IPR005185 Inner membrane component domain K08M4_RS17130 02dd01981aedf7863d870b906d59dcbb 144 PIRSF PIRSF028777 1 138 1.2E-53 T 05-07-2017 IPR031308 Uncharacterised conserved protein UCP028777 K08M4_RS10895 15701ebe5746c03b00bab22302b6bbe0 252 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 14 229 7.7E-38 T 05-07-2017 K08M4_RS10895 15701ebe5746c03b00bab22302b6bbe0 252 Hamap MF_00468 Sulfate transporter CysZ [cysZ]. 7 247 27.921 T 05-07-2017 IPR022985 Sulfate transporter CysZ GO:0000103|GO:0005887|GO:0015116 K08M4_RS05430 4b5efb70fe729bae780ada528080d316 226 Pfam PF09335 SNARE associated Golgi protein 65 181 6.3E-22 T 05-07-2017 IPR032816 SNARE associated Golgi protein K08M4_RS04175 e3d839ebe37f6b7a9d3b42d9cec55f5f 145 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 3 142 2.7E-35 T 05-07-2017 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 K08M4_RS04175 e3d839ebe37f6b7a9d3b42d9cec55f5f 145 Pfam PF02050 Flagellar FliJ protein 18 140 3.0E-28 T 05-07-2017 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 K08M4_RS12955 2331a89980e6d3cbe6adbfe8aff50b56 782 Gene3D G3DSA:2.60.450.10 48 203 6.7E-25 T 05-07-2017 K08M4_RS12955 2331a89980e6d3cbe6adbfe8aff50b56 782 Pfam PF03968 OstA-like protein 56 188 1.2E-19 T 05-07-2017 IPR005653 Organic solvent tolerance-like, N-terminal K08M4_RS12955 2331a89980e6d3cbe6adbfe8aff50b56 782 Pfam PF04453 Organic solvent tolerance protein 296 683 1.1E-111 T 05-07-2017 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 K08M4_RS12955 2331a89980e6d3cbe6adbfe8aff50b56 782 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 9 754 20.336 T 05-07-2017 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 K08M4_RS21000 2a6f47a9d0018c680d80846d2ffeed87 146 Gene3D G3DSA:3.40.930.10 1 144 2.6E-37 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS21000 2a6f47a9d0018c680d80846d2ffeed87 146 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 144 7.4E-30 T 05-07-2017 IPR002178 PTS EIIA type-2 domain K08M4_RS21000 2a6f47a9d0018c680d80846d2ffeed87 146 SUPERFAMILY SSF55804 1 144 1.05E-28 T 05-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 K08M4_RS00220 8dcce54cc825395c8e800afc3e418191 286 SUPERFAMILY SSF51658 30 255 2.49E-9 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain K08M4_RS00220 8dcce54cc825395c8e800afc3e418191 286 Pfam PF05114 Protein of unknown function (DUF692) 9 273 6.1E-103 T 05-07-2017 IPR007801 Uncharacterised protein family UPF0276 K08M4_RS00220 8dcce54cc825395c8e800afc3e418191 286 Gene3D G3DSA:3.20.20.150 7 282 7.3E-97 T 05-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain K08M4_RS00665 b7543ce07a50d7f45ba3154872349426 268 Pfam PF01177 Asp/Glu/Hydantoin racemase 13 217 7.1E-27 T 05-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS00665 b7543ce07a50d7f45ba3154872349426 268 TIGRFAM TIGR00067 glut_race: glutamate racemase 11 242 3.7E-71 T 05-07-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS00665 b7543ce07a50d7f45ba3154872349426 268 SUPERFAMILY SSF53681 113 260 7.85E-34 T 05-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS00665 b7543ce07a50d7f45ba3154872349426 268 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 76 84 - T 05-07-2017 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS00665 b7543ce07a50d7f45ba3154872349426 268 SUPERFAMILY SSF53681 10 110 1.83E-30 T 05-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS00665 b7543ce07a50d7f45ba3154872349426 268 Hamap MF_00258 Glutamate racemase [murI]. 9 256 32.423 T 05-07-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS00665 b7543ce07a50d7f45ba3154872349426 268 Gene3D G3DSA:3.40.50.1860 8 177 1.5E-45 T 05-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 K08M4_RS03930 45155f225fb151542ad2464dd9970298 176 SUPERFAMILY SSF54637 8 146 7.88E-29 T 05-07-2017 IPR029069 HotDog domain K08M4_RS03930 45155f225fb151542ad2464dd9970298 176 Gene3D G3DSA:3.10.129.10 11 136 5.4E-32 T 05-07-2017 IPR029069 HotDog domain K08M4_RS03930 45155f225fb151542ad2464dd9970298 176 Pfam PF13279 Thioesterase-like superfamily 18 122 4.9E-11 T 05-07-2017 K08M4_RS20710 9cbea0f448389d43550b27724ee409d8 441 Gene3D G3DSA:3.90.550.10 64 316 1.3E-30 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS20710 9cbea0f448389d43550b27724ee409d8 441 Pfam PF13641 Glycosyltransferase like family 2 64 297 4.7E-19 T 05-07-2017 K08M4_RS20710 9cbea0f448389d43550b27724ee409d8 441 SUPERFAMILY SSF53448 59 350 4.45E-42 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS08070 a31793c32e799e986599192b00d6e3a6 137 Gene3D G3DSA:1.10.720.30 19 77 5.5E-29 T 05-07-2017 IPR003034 SAP domain K08M4_RS08070 a31793c32e799e986599192b00d6e3a6 137 Pfam PF09905 Uncharacterized conserved protein (DUF2132) 11 73 2.4E-31 T 05-07-2017 IPR018668 DNA-binding protein VF530-like, bacteria GO:0003677 K08M4_RS07330 41f3c025d30b2e47b55ec85cd739254e 474 Pfam PF02706 Chain length determinant protein 8 149 1.3E-10 T 05-07-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 K08M4_RS07200 ed77866ed930ad91e027df9edb11dea4 222 SUPERFAMILY SSF161098 8 202 6.15E-33 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07200 ed77866ed930ad91e027df9edb11dea4 222 Gene3D G3DSA:1.10.3720.10 4 215 5.8E-37 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07200 ed77866ed930ad91e027df9edb11dea4 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 7 112 2.1E-14 T 05-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 K08M4_RS07200 ed77866ed930ad91e027df9edb11dea4 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 215 2.0E-14 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS19970 796f8855d29ee39122817cf319957592 150 Pfam PF10772 Protein of unknown function (DUF2597) 9 141 8.2E-53 T 05-07-2017 IPR019708 Bacteriophage HP1, Orf24 K08M4_RS01635 be5052275305d5185a6c7cde75a2b009 145 Pfam PF04945 YHS domain 39 83 8.2E-11 T 05-07-2017 IPR007029 YHS domain K08M4_RS12655 a3e39525841fba3e262cb13d981d1a7e 245 SUPERFAMILY SSF46626 17 208 2.07E-46 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS12655 a3e39525841fba3e262cb13d981d1a7e 245 Gene3D G3DSA:1.20.5.100 214 245 6.1E-11 T 05-07-2017 K08M4_RS12655 a3e39525841fba3e262cb13d981d1a7e 245 Pfam PF02167 Cytochrome C1 family 34 244 3.1E-15 T 05-07-2017 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 K08M4_RS12655 a3e39525841fba3e262cb13d981d1a7e 245 Gene3D G3DSA:1.10.760.10 16 210 1.3E-60 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS18425 e9c06e5c3df080846e537835745a9202 228 SUPERFAMILY SSF50630 92 223 1.31E-39 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS18425 e9c06e5c3df080846e537835745a9202 228 Gene3D G3DSA:2.40.70.10 90 217 1.1E-44 T 05-07-2017 IPR021109 Aspartic peptidase domain K08M4_RS18425 e9c06e5c3df080846e537835745a9202 228 Pfam PF05618 Putative ATP-dependant zinc protease 92 225 1.0E-41 T 05-07-2017 K08M4_RS18840 bb94f71990335827ff34a86e9fbca779 179 Pfam PF01292 Prokaryotic cytochrome b561 8 176 1.1E-29 T 05-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 K08M4_RS18840 bb94f71990335827ff34a86e9fbca779 179 SUPERFAMILY SSF81342 4 175 1.73E-34 T 05-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 K08M4_RS18840 bb94f71990335827ff34a86e9fbca779 179 Gene3D G3DSA:1.20.950.20 86 170 3.5E-6 T 05-07-2017 K08M4_RS18840 bb94f71990335827ff34a86e9fbca779 179 Gene3D G3DSA:1.20.950.20 4 73 9.7E-6 T 05-07-2017 K08M4_RS06685 0c1a36eba2329ebf23095eea7f473b97 122 Gene3D G3DSA:3.40.50.300 2 121 9.8E-20 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS06685 0c1a36eba2329ebf23095eea7f473b97 122 Pfam PF13671 AAA domain 3 98 2.2E-11 T 05-07-2017 K08M4_RS06685 0c1a36eba2329ebf23095eea7f473b97 122 SUPERFAMILY SSF52540 3 97 1.97E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07875 36d8599041432be2a4fcd342fd1987f7 161 Pfam PF14539 Domain of unknown function (DUF4442) 12 107 9.6E-8 T 05-07-2017 IPR027961 Protein of unknown function DUF4442 K08M4_RS07875 36d8599041432be2a4fcd342fd1987f7 161 SUPERFAMILY SSF54637 12 157 8.58E-17 T 05-07-2017 IPR029069 HotDog domain K08M4_RS07875 36d8599041432be2a4fcd342fd1987f7 161 Gene3D G3DSA:3.10.129.10 9 156 2.6E-27 T 05-07-2017 IPR029069 HotDog domain K08M4_RS07730 2e1aa962d96c85ca7c8687d2e5408b24 162 SUPERFAMILY SSF46689 16 132 5.73E-17 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS07730 2e1aa962d96c85ca7c8687d2e5408b24 162 Pfam PF13592 Winged helix-turn helix 99 156 2.1E-13 T 05-07-2017 IPR025959 Winged helix-turn helix domain K08M4_RS07730 2e1aa962d96c85ca7c8687d2e5408b24 162 Pfam PF13551 Winged helix-turn helix 24 83 1.4E-12 T 05-07-2017 K08M4_RS07730 2e1aa962d96c85ca7c8687d2e5408b24 162 Gene3D G3DSA:1.10.10.60 21 86 5.6E-6 T 05-07-2017 IPR009057 Homeodomain-like GO:0003677 K08M4_RS00640 a2e60cff6796936f7e913ac1901a99ad 123 ProDom PD076479 MEMBRANE INNER YIJD TRANSMEMBRANE Y0323 AAA SIMILAR A ACETYL-COENZYME VV0128 1 116 2.0E-50 T 05-07-2017 IPR009867 Protein of unknown function DUF1422 K08M4_RS00640 a2e60cff6796936f7e913ac1901a99ad 123 Pfam PF07226 Protein of unknown function (DUF1422) 10 119 8.3E-46 T 05-07-2017 IPR009867 Protein of unknown function DUF1422 K08M4_RS21200 1e7a4363d80ad51a271dbc7688b07055 164 Gene3D G3DSA:1.25.40.10 4 145 2.2E-4 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS21200 1e7a4363d80ad51a271dbc7688b07055 164 SUPERFAMILY SSF48452 6 91 9.87E-5 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS12065 20799b9a2a377a884cf58f79f98c8c4f 279 Gene3D G3DSA:3.30.1380.10 19 278 3.1E-99 T 05-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 K08M4_RS12065 20799b9a2a377a884cf58f79f98c8c4f 279 SUPERFAMILY SSF55166 19 278 8.24E-92 T 05-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 K08M4_RS12065 20799b9a2a377a884cf58f79f98c8c4f 279 PIRSF PIRSF018455 4 279 3.5E-109 T 05-07-2017 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 K08M4_RS12065 20799b9a2a377a884cf58f79f98c8c4f 279 Pfam PF03411 Penicillin-insensitive murein endopeptidase 34 276 2.2E-95 T 05-07-2017 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 K08M4_RS13975 9c66218276375aa172ae60538d3c59f5 297 SUPERFAMILY SSF53448 12 137 1.6E-5 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS13975 9c66218276375aa172ae60538d3c59f5 297 SUPERFAMILY SSF53448 167 242 1.6E-5 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS20195 3bc1feb23139005d457acfc98a74fb19 325 Gene3D G3DSA:3.40.50.1980 165 323 2.3E-25 T 05-07-2017 K08M4_RS20195 3bc1feb23139005d457acfc98a74fb19 325 SUPERFAMILY SSF53807 46 310 5.89E-56 T 05-07-2017 K08M4_RS20195 3bc1feb23139005d457acfc98a74fb19 325 Gene3D G3DSA:3.40.50.1980 50 164 2.2E-31 T 05-07-2017 K08M4_RS20195 3bc1feb23139005d457acfc98a74fb19 325 Pfam PF01497 Periplasmic binding protein 70 297 2.3E-26 T 05-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 K08M4_RS11710 2e91a3a86afac0b0ae002ee5060242e4 294 SUPERFAMILY SSF111331 8 290 7.98E-92 T 05-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain K08M4_RS11710 2e91a3a86afac0b0ae002ee5060242e4 294 Gene3D G3DSA:3.40.50.10330 3 151 1.7E-40 T 05-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 K08M4_RS11710 2e91a3a86afac0b0ae002ee5060242e4 294 Gene3D G3DSA:2.60.200.30 152 262 9.0E-41 T 05-07-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 K08M4_RS11710 2e91a3a86afac0b0ae002ee5060242e4 294 Pfam PF01513 ATP-NAD kinase 8 273 4.6E-71 T 05-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 K08M4_RS11710 2e91a3a86afac0b0ae002ee5060242e4 294 Hamap MF_00361 NAD kinase [nadK]. 6 289 33.126 T 05-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 K08M4_RS06920 ca09738f7c42e6968b63ca1faa406cfe 198 Pfam PF01810 LysE type translocator 12 197 6.1E-41 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS19170 9351ea1ceba0fd16958dfeef247854db 474 Pfam PF02321 Outer membrane efflux protein 28 213 2.8E-20 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS19170 9351ea1ceba0fd16958dfeef247854db 474 Pfam PF02321 Outer membrane efflux protein 244 430 3.6E-33 T 05-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 K08M4_RS19170 9351ea1ceba0fd16958dfeef247854db 474 Gene3D G3DSA:1.20.1600.10 23 431 6.8E-61 T 05-07-2017 K08M4_RS19170 9351ea1ceba0fd16958dfeef247854db 474 SUPERFAMILY SSF56954 3 432 2.62E-68 T 05-07-2017 K08M4_RS20390 8f1c8cd8a8e6574e31533504da826d89 181 Gene3D G3DSA:3.40.630.30 3 173 4.9E-49 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS20390 8f1c8cd8a8e6574e31533504da826d89 181 SUPERFAMILY SSF55729 4 173 1.26E-41 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS20390 8f1c8cd8a8e6574e31533504da826d89 181 Pfam PF13302 Acetyltransferase (GNAT) domain 28 150 1.4E-21 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS00045 44a7990b6eab892e84cb6a1bf85c0422 184 Pfam PF01169 Uncharacterized protein family UPF0016 103 177 1.0E-20 T 05-07-2017 IPR001727 Gdt1 family GO:0032472 K08M4_RS00045 44a7990b6eab892e84cb6a1bf85c0422 184 Pfam PF01169 Uncharacterized protein family UPF0016 7 80 3.2E-20 T 05-07-2017 IPR001727 Gdt1 family GO:0032472 K08M4_RS16550 1b2daaba0b370b7e82daaaf8eb307148 338 SMART SM00267 168 338 4.8E-52 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS16550 1b2daaba0b370b7e82daaaf8eb307148 338 Pfam PF00990 Diguanylate cyclase, GGDEF domain 179 334 1.4E-40 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS16550 1b2daaba0b370b7e82daaaf8eb307148 338 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 176 335 2.6E-40 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS16550 1b2daaba0b370b7e82daaaf8eb307148 338 Gene3D G3DSA:3.30.70.270 181 336 1.4E-46 T 05-07-2017 K08M4_RS16550 1b2daaba0b370b7e82daaaf8eb307148 338 SUPERFAMILY SSF55073 185 336 2.9E-42 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS13835 b171c805e2f8f2985baf42c1d358141e 259 PIRSF PIRSF006648 2 252 3.4E-15 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 K08M4_RS13835 b171c805e2f8f2985baf42c1d358141e 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 197 216 2.6E-6 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 K08M4_RS13835 b171c805e2f8f2985baf42c1d358141e 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 30 51 2.6E-6 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 K08M4_RS13835 b171c805e2f8f2985baf42c1d358141e 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 177 196 2.6E-6 T 05-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 K08M4_RS13835 b171c805e2f8f2985baf42c1d358141e 259 Pfam PF01061 ABC-2 type transporter 10 219 1.4E-33 T 05-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 K08M4_RS16685 760479a4c2e600f9be9d7296331d0834 116 Pfam PF08888 HopJ type III effector protein 4 111 5.0E-49 T 05-07-2017 IPR014984 HopJ type III effector protein K08M4_RS16685 760479a4c2e600f9be9d7296331d0834 116 Gene3D G3DSA:3.20.160.10 1 114 3.6E-51 T 05-07-2017 K08M4_RS13220 d2761cf0a07d8a1951b8eddbac904349 587 Pfam PF15864 Protein glycosylation ligase 174 199 1.3E-7 T 05-07-2017 IPR031726 Protein glycosylation ligase domain K08M4_RS13220 d2761cf0a07d8a1951b8eddbac904349 587 Pfam PF04932 O-Antigen ligase 222 367 7.8E-18 T 05-07-2017 IPR007016 O-antigen ligase-related K08M4_RS13220 d2761cf0a07d8a1951b8eddbac904349 587 Pfam PF11846 Virulence factor membrane-bound polymerase, C-terminal 388 575 1.9E-66 T 05-07-2017 IPR021797 Virulence factor membrane-bound polymerase, C-terminal K08M4_RS06895 88bdf7e242c2d546729763d02cf87a13 332 SUPERFAMILY SSF64182 4 327 1.31E-40 T 05-07-2017 K08M4_RS10050 993fb8cb30b3047ff58d4b2bacdb4055 63 SUPERFAMILY SSF51338 1 55 9.32E-11 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS10050 993fb8cb30b3047ff58d4b2bacdb4055 63 Gene3D G3DSA:2.30.40.10 3 52 6.8E-10 T 05-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 K08M4_RS13950 9979de10f39830be37f2e8cc34e0518f 323 Pfam PF00534 Glycosyl transferases group 1 130 265 4.4E-11 T 05-07-2017 IPR001296 Glycosyl transferase, family 1 K08M4_RS13950 9979de10f39830be37f2e8cc34e0518f 323 SUPERFAMILY SSF53756 13 302 4.71E-38 T 05-07-2017 K08M4_RS13950 9979de10f39830be37f2e8cc34e0518f 323 Gene3D G3DSA:3.40.50.2000 154 247 2.2E-8 T 05-07-2017 K08M4_RS15270 3c3e0ea6f647181734333304aaf7c146 56 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 48 18.629 T 05-07-2017 IPR009760 Protein of unknown function DUF1328 GO:0005886 K08M4_RS15270 3c3e0ea6f647181734333304aaf7c146 56 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 2.3E-13 T 05-07-2017 IPR009760 Protein of unknown function DUF1328 GO:0005886 K08M4_RS15270 3c3e0ea6f647181734333304aaf7c146 56 PIRSF PIRSF036466 1 55 7.4E-21 T 05-07-2017 IPR009760 Protein of unknown function DUF1328 GO:0005886 K08M4_RS11820 5ff8cbb167c8ea09e73da55f736c742e 306 SUPERFAMILY SSF55186 138 288 3.36E-14 T 05-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 K08M4_RS05960 1f29e6847098d8bfb530d05ec05fa569 456 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 406 422 - T 05-07-2017 IPR031312 Sodium/sulphate symporter, conserved site Reactome: R-HSA-433137 K08M4_RS05960 1f29e6847098d8bfb530d05ec05fa569 456 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 36 456 2.2E-113 T 05-07-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 K08M4_RS05960 1f29e6847098d8bfb530d05ec05fa569 456 Pfam PF00939 Sodium:sulfate symporter transmembrane region 41 456 7.6E-60 T 05-07-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 K08M4_RS03420 6105772ffca2b02c4b79fda129be7ef4 382 Pfam PF02417 Chromate transporter 212 372 8.4E-32 T 05-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 K08M4_RS03420 6105772ffca2b02c4b79fda129be7ef4 382 Pfam PF02417 Chromate transporter 3 168 1.4E-32 T 05-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 K08M4_RS03420 6105772ffca2b02c4b79fda129be7ef4 382 TIGRFAM TIGR00937 2A51: chromate efflux transporter 8 368 4.4E-86 T 05-07-2017 IPR014047 Chromate transporter, long chain K08M4_RS03420 6105772ffca2b02c4b79fda129be7ef4 382 PIRSF PIRSF004810 1 381 6.7E-111 T 05-07-2017 IPR014047 Chromate transporter, long chain K08M4_RS19470 60c430c91e342f79c67e4a86f0731eba 146 Pfam PF07007 Protein of unknown function (DUF1311) 27 117 2.1E-13 T 05-07-2017 IPR009739 Protein of unknown function DUF1311 K08M4_RS01095 771d5a7485f366569adbcfcdfae9d77e 142 Pfam PF05656 Protein of unknown function (DUF805) 8 139 3.4E-21 T 05-07-2017 IPR008523 Protein of unknown function DUF805 GO:0016021 K08M4_RS04720 f7f14068a9331462ea47f10debce2d21 333 Pfam PF11279 Protein of unknown function (DUF3080) 34 330 1.8E-90 T 05-07-2017 IPR021431 Protein of unknown function DUF3080 K08M4_RS01105 9d4f4783a7dce7024135ebea28ca4993 208 Gene3D G3DSA:1.10.10.10 6 98 1.3E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS01105 9d4f4783a7dce7024135ebea28ca4993 208 Pfam PF08220 DeoR-like helix-turn-helix domain 5 46 5.1E-6 T 05-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 K08M4_RS01105 9d4f4783a7dce7024135ebea28ca4993 208 SUPERFAMILY SSF46785 3 183 1.0E-35 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS02350 7752c2373ecd53e4da938b1ac8de0d9a 237 Pfam PF04402 Protein of unknown function (DUF541) 35 233 8.5E-41 T 05-07-2017 IPR007497 Protein of unknown function DUF541 K08M4_RS19010 f34740f82c547d2c7194ef86d761f79f 341 Pfam PF01548 Transposase 8 147 3.4E-16 T 05-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 K08M4_RS19010 f34740f82c547d2c7194ef86d761f79f 341 Pfam PF02371 Transposase IS116/IS110/IS902 family 214 288 2.1E-23 T 05-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 K08M4_RS06700 5ca3d27c588730350f72cf68f0f8dc43 46 SUPERFAMILY SSF55073 3 39 7.3E-7 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS06700 5ca3d27c588730350f72cf68f0f8dc43 46 Pfam PF00990 Diguanylate cyclase, GGDEF domain 5 39 5.8E-8 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS06700 5ca3d27c588730350f72cf68f0f8dc43 46 Gene3D G3DSA:3.30.70.270 3 38 4.0E-8 T 05-07-2017 K08M4_RS20765 6c9726bb015325aea44273b8aa78340c 511 Gene3D G3DSA:3.90.76.10 55 177 3.1E-25 T 05-07-2017 K08M4_RS20765 6c9726bb015325aea44273b8aa78340c 511 Gene3D G3DSA:3.10.105.10 275 479 3.1E-37 T 05-07-2017 K08M4_RS20765 6c9726bb015325aea44273b8aa78340c 511 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 69 421 1.9E-69 T 05-07-2017 IPR000914 Solute-binding protein family 5 domain K08M4_RS20765 6c9726bb015325aea44273b8aa78340c 511 PIRSF PIRSF002741 22 510 2.9E-73 T 05-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 K08M4_RS20765 6c9726bb015325aea44273b8aa78340c 511 Gene3D G3DSA:3.40.190.10 178 274 2.0E-26 T 05-07-2017 K08M4_RS20765 6c9726bb015325aea44273b8aa78340c 511 SUPERFAMILY SSF53850 32 507 1.09E-100 T 05-07-2017 K08M4_RS12195 1e21688ad3bebbff61c456c69df1fc50 371 SUPERFAMILY SSF53067 6 40 1.88E-28 T 05-07-2017 K08M4_RS12195 1e21688ad3bebbff61c456c69df1fc50 371 SUPERFAMILY SSF53067 67 112 1.88E-28 T 05-07-2017 K08M4_RS12195 1e21688ad3bebbff61c456c69df1fc50 371 SUPERFAMILY SSF53067 144 344 1.88E-28 T 05-07-2017 K08M4_RS12195 1e21688ad3bebbff61c456c69df1fc50 371 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 5 370 40.682 T 05-07-2017 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 K08M4_RS12195 1e21688ad3bebbff61c456c69df1fc50 371 Gene3D G3DSA:3.30.420.40 6 197 1.3E-71 T 05-07-2017 K08M4_RS12195 1e21688ad3bebbff61c456c69df1fc50 371 Pfam PF03702 Uncharacterised protein family (UPF0075) 6 369 1.2E-162 T 05-07-2017 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 K08M4_RS01690 598a338028b92418ee2806d9a6bc0cc6 171 Pfam PF11736 Protein of unknown function (DUF3299) 34 168 4.9E-45 T 05-07-2017 IPR021727 Protein of unknown function DUF3299 K08M4_RS08475 d2a7590a095f3692a8978d3a797bd404 205 Pfam PF13505 Outer membrane protein beta-barrel domain 7 188 1.0E-24 T 05-07-2017 IPR027385 Outer membrane protein beta-barrel K08M4_RS08475 d2a7590a095f3692a8978d3a797bd404 205 Gene3D G3DSA:2.40.160.20 9 204 8.1E-28 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS08475 d2a7590a095f3692a8978d3a797bd404 205 SUPERFAMILY SSF56925 22 205 6.8E-23 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS07125 ef69c148efdf6c29bb56929ee47a24d2 171 Gene3D G3DSA:3.40.50.300 1 94 5.8E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS07125 ef69c148efdf6c29bb56929ee47a24d2 171 SUPERFAMILY SSF52540 1 111 3.52E-10 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS04210 ebc92ef4b4cd158316f929fc726fd8ce 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 1.2E-26 T 05-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 K08M4_RS04210 ebc92ef4b4cd158316f929fc726fd8ce 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 1.8E-31 T 05-07-2017 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 K08M4_RS04210 ebc92ef4b4cd158316f929fc726fd8ce 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 7.7E-16 T 05-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 K08M4_RS04210 ebc92ef4b4cd158316f929fc726fd8ce 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 7.7E-16 T 05-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 K08M4_RS04210 ebc92ef4b4cd158316f929fc726fd8ce 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 7.7E-16 T 05-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 K08M4_RS04210 ebc92ef4b4cd158316f929fc726fd8ce 89 PIRSF PIRSF004669 1 89 2.9E-28 T 05-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 K08M4_RS16995 0048cdc4bc355d9842e21d2d3289ac94 703 TIGRFAM TIGR04456 LruC_dom: LruC domain 422 691 2.1E-63 T 05-07-2017 IPR031025 LruC domain K08M4_RS16995 0048cdc4bc355d9842e21d2d3289ac94 703 Pfam PF16130 Domain of unknown function (DUF4842) 455 690 5.3E-54 T 05-07-2017 IPR032295 Domain of unknown function DUF4842 K08M4_RS20160 cbe6e01b7d8f6c4a81acd13e536c2187 202 SUPERFAMILY SSF49785 38 188 1.02E-16 T 05-07-2017 IPR008979 Galactose-binding domain-like K08M4_RS20160 cbe6e01b7d8f6c4a81acd13e536c2187 202 Pfam PF08547 Complex I intermediate-associated protein 30 (CIA30) 39 189 1.6E-37 T 05-07-2017 IPR013857 NADH:ubiquinone oxidoreductase intermediate-associated protein 30 Reactome: R-HSA-6799198 K08M4_RS00770 a1e9cab5d5e354e6ef0e9b9c2a382416 307 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 82 235 4.3E-11 T 05-07-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 K08M4_RS00770 a1e9cab5d5e354e6ef0e9b9c2a382416 307 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 3 307 6.7E-146 T 05-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 K08M4_RS00770 a1e9cab5d5e354e6ef0e9b9c2a382416 307 Gene3D G3DSA:3.40.50.300 2 307 4.6E-105 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00770 a1e9cab5d5e354e6ef0e9b9c2a382416 307 SUPERFAMILY SSF52540 3 307 1.11E-68 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS00770 a1e9cab5d5e354e6ef0e9b9c2a382416 307 PIRSF PIRSF000545 1 307 1.0E-143 T 05-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 K08M4_RS00770 a1e9cab5d5e354e6ef0e9b9c2a382416 307 Hamap MF_00215 Pantothenate kinase [coaA]. 1 307 173.914 T 05-07-2017 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 K08M4_RS04515 0e5d1a98880ad93deb4bdccec6aaf409 173 Pfam PF03358 NADPH-dependent FMN reductase 1 126 7.9E-25 T 05-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 K08M4_RS04515 0e5d1a98880ad93deb4bdccec6aaf409 173 Gene3D G3DSA:3.40.50.360 1 173 8.7E-33 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS04515 0e5d1a98880ad93deb4bdccec6aaf409 173 SUPERFAMILY SSF52218 1 173 2.51E-34 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS07550 a64792c512c2f20be668ba68daccfc9e 357 Pfam PF01292 Prokaryotic cytochrome b561 129 310 8.0E-25 T 05-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 K08M4_RS07550 a64792c512c2f20be668ba68daccfc9e 357 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 126 330 2.9E-79 T 05-07-2017 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 K08M4_RS07550 a64792c512c2f20be668ba68daccfc9e 357 Gene3D G3DSA:1.20.950.20 123 337 1.8E-62 T 05-07-2017 K08M4_RS07550 a64792c512c2f20be668ba68daccfc9e 357 SUPERFAMILY SSF81342 123 334 2.51E-44 T 05-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 K08M4_RS07235 0990156f965a0e5c1c96dc36ca814326 57 Pfam PF11665 Protein of unknown function (DUF3265) 30 57 3.2E-13 T 05-07-2017 IPR021681 Protein of unknown function DUF3265 K08M4_RS19430 da541915cd574674d55ca2b385f5c461 347 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 11 319 6.2E-16 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS19430 da541915cd574674d55ca2b385f5c461 347 SUPERFAMILY SSF56219 198 341 3.96E-35 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS19430 da541915cd574674d55ca2b385f5c461 347 SUPERFAMILY SSF56219 5 167 3.96E-35 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS19430 da541915cd574674d55ca2b385f5c461 347 Gene3D G3DSA:3.60.10.10 199 341 1.1E-12 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS19430 da541915cd574674d55ca2b385f5c461 347 Gene3D G3DSA:3.60.10.10 34 165 1.1E-12 T 05-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase K08M4_RS04295 267a73a04fb36b94db20d184b4a76830 246 Pfam PF01578 Cytochrome C assembly protein 19 184 3.6E-32 T 05-07-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 K08M4_RS04295 267a73a04fb36b94db20d184b4a76830 246 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 45 228 1.4E-84 T 05-07-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04295 267a73a04fb36b94db20d184b4a76830 246 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 156 182 1.8E-64 T 05-07-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04295 267a73a04fb36b94db20d184b4a76830 246 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 100 120 1.8E-64 T 05-07-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04295 267a73a04fb36b94db20d184b4a76830 246 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 121 141 1.8E-64 T 05-07-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04295 267a73a04fb36b94db20d184b4a76830 246 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 62 82 1.8E-64 T 05-07-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04295 267a73a04fb36b94db20d184b4a76830 246 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 45 62 1.8E-64 T 05-07-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04295 267a73a04fb36b94db20d184b4a76830 246 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 204 228 1.8E-64 T 05-07-2017 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS19310 2ae5c8887ac650a3aaafbc5be3a37729 216 Pfam PF01810 LysE type translocator 19 209 3.2E-31 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS13630 b4d2535e917241a9c556d824363ff854 181 SMART SM00479 7 180 5.5E-21 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS13630 b4d2535e917241a9c556d824363ff854 181 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 43.372 T 05-07-2017 IPR022894 Oligoribonuclease GO:0016788 K08M4_RS13630 b4d2535e917241a9c556d824363ff854 181 Pfam PF00929 Exonuclease 9 170 8.3E-36 T 05-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III K08M4_RS13630 b4d2535e917241a9c556d824363ff854 181 Gene3D G3DSA:3.30.420.10 4 178 6.0E-75 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS13630 b4d2535e917241a9c556d824363ff854 181 SUPERFAMILY SSF53098 3 179 1.14E-49 T 05-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 K08M4_RS05535 02f42b0202285efec364e0bf72a419bb 528 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 501 1.8E-178 T 05-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 K08M4_RS07440 17a32747e24fb1676385df61121c3d26 267 Pfam PF04116 Fatty acid hydroxylase superfamily 88 224 1.5E-25 T 05-07-2017 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 K08M4_RS18920 4b70f37a8089afa7394c332193eff28b 158 PIRSF PIRSF003174 1 153 3.1E-49 T 05-07-2017 IPR010292 Uncharacterised protein family CreA K08M4_RS18920 4b70f37a8089afa7394c332193eff28b 158 Pfam PF05981 CreA protein 22 144 1.7E-44 T 05-07-2017 IPR010292 Uncharacterised protein family CreA K08M4_RS16305 f5ea96a8fea89f8176f57b7c356df3ed 368 Pfam PF01553 Acyltransferase 92 240 5.9E-11 T 05-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 K08M4_RS16305 f5ea96a8fea89f8176f57b7c356df3ed 368 SUPERFAMILY SSF69593 83 323 4.05E-10 T 05-07-2017 K08M4_RS16305 f5ea96a8fea89f8176f57b7c356df3ed 368 Gene3D G3DSA:3.40.1130.10 47 249 1.1E-8 T 05-07-2017 K08M4_RS09230 821e1e8270e7e3a57734635a5a7c32f1 41 Pfam PF08056 Tryptophan operon leader peptide 1 41 1.6E-18 T 05-07-2017 IPR012639 Tryptophan operon leader peptide K08M4_RS12225 0f7feabf7c77413f0dda48a93e6de08e 318 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 6 288 5.0E-99 T 05-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 K08M4_RS12225 0f7feabf7c77413f0dda48a93e6de08e 318 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 5 290 37.791 T 05-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 K08M4_RS12225 0f7feabf7c77413f0dda48a93e6de08e 318 Pfam PF02401 LytB protein 7 286 7.3E-93 T 05-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 K08M4_RS03945 82f23d357822bcf35694b61defb1ae93 120 SUPERFAMILY SSF54637 16 114 1.08E-15 T 05-07-2017 IPR029069 HotDog domain K08M4_RS03945 82f23d357822bcf35694b61defb1ae93 120 PIRSF PIRSF030962 1 120 2.6E-43 T 05-07-2017 IPR016962 Dehydrase, ECs4332, predicted K08M4_RS03945 82f23d357822bcf35694b61defb1ae93 120 Gene3D G3DSA:3.10.129.10 16 114 3.7E-15 T 05-07-2017 IPR029069 HotDog domain K08M4_RS16140 dd78b6e05f44b4213c96a9ff3fdf1398 216 Pfam PF09335 SNARE associated Golgi protein 45 169 4.6E-16 T 05-07-2017 IPR032816 SNARE associated Golgi protein K08M4_RS00670 19b97064ab42fca20273db8b008c2074 150 SUPERFAMILY SSF54928 48 140 6.85E-27 T 05-07-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 K08M4_RS00670 19b97064ab42fca20273db8b008c2074 150 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 63 132 4.6E-18 T 05-07-2017 IPR000504 RNA recognition motif domain GO:0003676 K08M4_RS00670 19b97064ab42fca20273db8b008c2074 150 Gene3D G3DSA:3.30.70.330 49 141 4.1E-28 T 05-07-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 K08M4_RS00670 19b97064ab42fca20273db8b008c2074 150 SMART SM00360 62 134 7.2E-20 T 05-07-2017 IPR000504 RNA recognition motif domain GO:0003676 K08M4_RS19725 b87213a3e265cd14b9f390ebeeb1e438 339 Pfam PF11168 Protein of unknown function (DUF2955) 14 153 2.1E-38 T 05-07-2017 IPR022604 Protein of unknown function DUF2955 K08M4_RS06690 e78b588504d54404c39955ef2a82745e 140 Pfam PF12975 Domain of unknown function (DUF3859) 5 125 1.9E-46 T 05-07-2017 IPR024331 Domain of unknown function DUF3859 K08M4_RS15330 678c46fda19cf67aaf31fc5caf9b5cce 184 Gene3D G3DSA:1.20.1550.10 10 90 1.1E-12 T 05-07-2017 IPR023380 Disulphide bond formation protein DsbB-like domain K08M4_RS15330 678c46fda19cf67aaf31fc5caf9b5cce 184 Pfam PF02600 Disulfide bond formation protein DsbB 9 90 1.7E-13 T 05-07-2017 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 K08M4_RS15330 678c46fda19cf67aaf31fc5caf9b5cce 184 SUPERFAMILY SSF158442 11 122 9.68E-22 T 05-07-2017 K08M4_RS06980 45c6b05e82e76067233073831c2a6503 86 Pfam PF11730 Protein of unknown function (DUF3297) 13 83 1.2E-34 T 05-07-2017 IPR021724 Protein of unknown function DUF3297 K08M4_RS21460 9b79bb32531dac50dbb3ae3361079535 479 Pfam PF03600 Citrate transporter 49 424 1.0E-60 T 05-07-2017 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 K08M4_RS08925 1caac15f06a69e58c3e6ba6a269f4b86 122 SUPERFAMILY SSF89360 15 108 2.94E-21 T 05-07-2017 IPR000361 FeS cluster biogenesis K08M4_RS08925 1caac15f06a69e58c3e6ba6a269f4b86 122 Pfam PF01521 Iron-sulphur cluster biosynthesis 21 118 1.1E-16 T 05-07-2017 IPR000361 FeS cluster biogenesis K08M4_RS08925 1caac15f06a69e58c3e6ba6a269f4b86 122 Gene3D G3DSA:2.60.300.12 21 111 3.7E-22 T 05-07-2017 IPR000361 FeS cluster biogenesis K08M4_RS08925 1caac15f06a69e58c3e6ba6a269f4b86 122 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 21 121 2.2E-26 T 05-07-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 K08M4_RS08925 1caac15f06a69e58c3e6ba6a269f4b86 122 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 103 120 - T 05-07-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site K08M4_RS06455 387e83e3dcef48b50874c15d75b3feea 298 SUPERFAMILY SSF103481 43 132 5.1E-6 T 05-07-2017 K08M4_RS06455 387e83e3dcef48b50874c15d75b3feea 298 SUPERFAMILY SSF103481 184 282 3.53E-9 T 05-07-2017 K08M4_RS06455 387e83e3dcef48b50874c15d75b3feea 298 Pfam PF00892 EamA-like transporter family 7 131 4.6E-8 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS06455 387e83e3dcef48b50874c15d75b3feea 298 Pfam PF00892 EamA-like transporter family 142 280 8.1E-17 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS17175 42caef9910bafba8e20ebdb8238e5123 199 Pfam PF13489 Methyltransferase domain 33 141 2.8E-13 T 05-07-2017 K08M4_RS17175 42caef9910bafba8e20ebdb8238e5123 199 Gene3D G3DSA:3.40.50.150 1 173 8.5E-26 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS17175 42caef9910bafba8e20ebdb8238e5123 199 SUPERFAMILY SSF53335 4 193 1.69E-29 T 05-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase K08M4_RS16010 f99ad4bb2c591031ac16f3b6d895e22c 335 Gene3D G3DSA:3.40.50.410 94 294 8.2E-30 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS16010 f99ad4bb2c591031ac16f3b6d895e22c 335 Pfam PF00092 von Willebrand factor type A domain 99 291 3.0E-33 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS16010 f99ad4bb2c591031ac16f3b6d895e22c 335 SMART SM00327 97 298 5.8E-19 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS16010 f99ad4bb2c591031ac16f3b6d895e22c 335 SUPERFAMILY SSF53300 95 294 9.64E-38 T 05-07-2017 IPR002035 von Willebrand factor, type A K08M4_RS17730 5aa3cc420137e29361a73b2e4ad8a900 326 Pfam PF03595 Voltage-dependent anion channel 11 304 5.7E-28 T 05-07-2017 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 K08M4_RS01740 c118b9e7a68f6a6d210539853f5310b0 117 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 5 112 1.4E-25 T 05-07-2017 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like K08M4_RS01740 c118b9e7a68f6a6d210539853f5310b0 117 Gene3D G3DSA:3.10.490.10 1 114 3.6E-39 T 05-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like K08M4_RS01740 c118b9e7a68f6a6d210539853f5310b0 117 SUPERFAMILY SSF110857 3 114 2.49E-33 T 05-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like K08M4_RS21580 8bc025c4758e8d4546d1d2a3e4a4b38b 423 Pfam PF01593 Flavin containing amine oxidoreductase 11 306 3.6E-22 T 05-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 K08M4_RS21580 8bc025c4758e8d4546d1d2a3e4a4b38b 423 SUPERFAMILY SSF51905 2 302 1.17E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS21580 8bc025c4758e8d4546d1d2a3e4a4b38b 423 SUPERFAMILY SSF51905 382 409 1.17E-51 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS21580 8bc025c4758e8d4546d1d2a3e4a4b38b 423 Gene3D G3DSA:3.50.50.60 2 94 1.4E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS21580 8bc025c4758e8d4546d1d2a3e4a4b38b 423 Gene3D G3DSA:3.50.50.60 202 302 1.4E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS21580 8bc025c4758e8d4546d1d2a3e4a4b38b 423 Gene3D G3DSA:3.50.50.60 140 141 1.4E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS05125 e543147dd1524856f0dbe7e916405014 77 SUPERFAMILY SSF47336 2 76 3.27E-23 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS05125 e543147dd1524856f0dbe7e916405014 77 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.652 T 05-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS05125 e543147dd1524856f0dbe7e916405014 77 Gene3D G3DSA:1.10.1200.10 3 75 1.6E-34 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS05125 e543147dd1524856f0dbe7e916405014 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 76 4.7E-36 T 05-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS05125 e543147dd1524856f0dbe7e916405014 77 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 75 3.0E-11 T 05-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 K08M4_RS05125 e543147dd1524856f0dbe7e916405014 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 05-07-2017 IPR006162 Phosphopantetheine attachment site K08M4_RS05125 e543147dd1524856f0dbe7e916405014 77 Pfam PF00550 Phosphopantetheine attachment site 6 73 2.0E-16 T 05-07-2017 IPR009081 Phosphopantetheine binding ACP domain K08M4_RS03825 425d2fe26e011f061b28f6162e2e2bb9 269 Pfam PF13369 Transglutaminase-like superfamily 34 184 3.1E-41 T 05-07-2017 IPR032698 Protein SirB1, N-terminal K08M4_RS03825 425d2fe26e011f061b28f6162e2e2bb9 269 Pfam PF13371 Tetratricopeptide repeat 187 259 1.1E-23 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS03825 425d2fe26e011f061b28f6162e2e2bb9 269 Gene3D G3DSA:1.25.40.10 187 252 2.2E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS03825 425d2fe26e011f061b28f6162e2e2bb9 269 SUPERFAMILY SSF48452 190 255 1.66E-6 T 05-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 K08M4_RS12510 860affdb474256d04b292ec8450c24b7 259 Pfam PF01925 Sulfite exporter TauE/SafE 11 245 3.5E-43 T 05-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 K08M4_RS15320 91363b2e0a1c8ad890d2aa6002b84adc 351 Pfam PF01594 Domain of unknown function DUF20 21 340 5.2E-52 T 05-07-2017 IPR002549 Transmembrane protein TqsA-like K08M4_RS13815 8267fb1adc86248c58f3527c8d01b045 350 Gene3D G3DSA:3.40.225.10 2 192 1.4E-18 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal K08M4_RS13815 8267fb1adc86248c58f3527c8d01b045 350 SUPERFAMILY SSF53639 2 191 4.71E-19 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal K08M4_RS13815 8267fb1adc86248c58f3527c8d01b045 350 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 3 191 8.0E-19 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal K08M4_RS13815 8267fb1adc86248c58f3527c8d01b045 350 SMART SM01007 3 202 2.1E-8 T 05-07-2017 IPR001303 Class II aldolase/adducin N-terminal K08M4_RS17085 edd9dd6edb241db032aabb724e3bcd85 427 Pfam PF02687 FtsX-like permease family 297 420 3.8E-15 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 K08M4_RS17085 edd9dd6edb241db032aabb724e3bcd85 427 Pfam PF12704 MacB-like periplasmic core domain 20 255 1.3E-27 T 05-07-2017 IPR025857 MacB-like periplasmic core domain K08M4_RS15250 097fce7761f9a01da0a3345e4b63f72e 128 SUPERFAMILY SSF51182 11 127 7.13E-24 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS15250 097fce7761f9a01da0a3345e4b63f72e 128 Gene3D G3DSA:2.60.120.10 13 111 2.3E-15 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS15250 097fce7761f9a01da0a3345e4b63f72e 128 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 118 2.0E-63 T 05-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 K08M4_RS15250 097fce7761f9a01da0a3345e4b63f72e 128 Pfam PF06339 Ectoine synthase 1 127 9.1E-60 T 05-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 K08M4_RS15250 097fce7761f9a01da0a3345e4b63f72e 128 Hamap MF_01255 L-ectoine synthase [ectC]. 1 128 38.355 T 05-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 K08M4_RS06300 a1ce2cd4ef8b2bfc2b2fba8369769fc2 126 SUPERFAMILY SSF142906 1 118 1.18E-27 T 05-07-2017 K08M4_RS06300 a1ce2cd4ef8b2bfc2b2fba8369769fc2 126 Pfam PF04237 YjbR 13 102 4.6E-12 T 05-07-2017 IPR007351 Uncharacterised protein YjbR K08M4_RS08890 b9be28406b31927d43cba3513631aa49 83 TIGRFAM TIGR03643 TIGR03643: TIGR03643 family protein 8 77 4.4E-35 T 05-07-2017 IPR019882 Conserved hypothetical protein CHP03643 K08M4_RS08890 b9be28406b31927d43cba3513631aa49 83 Pfam PF10985 Protein of unknown function (DUF2805) 9 79 3.9E-35 T 05-07-2017 IPR019882 Conserved hypothetical protein CHP03643 K08M4_RS08935 98718a9214771e4b973820abea0878eb 278 Pfam PF01458 Uncharacterized protein family (UPF0051) 24 246 4.7E-63 T 05-07-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 K08M4_RS08935 98718a9214771e4b973820abea0878eb 278 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 2 261 5.5E-71 T 05-07-2017 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 K08M4_RS08935 98718a9214771e4b973820abea0878eb 278 SUPERFAMILY SSF101960 1 272 4.71E-76 T 05-07-2017 K08M4_RS16585 6ce327361043e366ad98bc4da54c2095 300 Pfam PF03253 Urea transporter 11 291 6.4E-52 T 05-07-2017 IPR004937 Urea transporter GO:0015204|GO:0016021|GO:0071918 Reactome: R-HSA-425366 K08M4_RS16585 6ce327361043e366ad98bc4da54c2095 300 Gene3D G3DSA:1.10.3430.10 4 299 6.6E-64 T 05-07-2017 IPR029020 Ammonium/urea transporter K08M4_RS03470 02a2b1ddf16260acf81c7dbee91f8d4d 417 Gene3D G3DSA:3.40.50.1820 159 302 2.9E-18 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS03470 02a2b1ddf16260acf81c7dbee91f8d4d 417 Gene3D G3DSA:3.40.50.1820 349 391 2.9E-18 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS03470 02a2b1ddf16260acf81c7dbee91f8d4d 417 SUPERFAMILY SSF53474 49 412 3.64E-39 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS03470 02a2b1ddf16260acf81c7dbee91f8d4d 417 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 7 415 2.7E-217 T 05-07-2017 IPR010520 UPF0255 family K08M4_RS10710 547315b43d4dd68a5a1c8f31d74966ef 92 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 6 78 1.9E-23 T 05-07-2017 IPR011893 Selenoprotein, Rdx type K08M4_RS10710 547315b43d4dd68a5a1c8f31d74966ef 92 Gene3D G3DSA:3.40.30.10 3 91 1.8E-42 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS10710 547315b43d4dd68a5a1c8f31d74966ef 92 Pfam PF10262 Rdx family 5 78 8.1E-31 T 05-07-2017 IPR011893 Selenoprotein, Rdx type K08M4_RS10710 547315b43d4dd68a5a1c8f31d74966ef 92 SUPERFAMILY SSF52833 4 87 1.99E-28 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS06580 a6d0f0d69a9bbade1e2f60df8d2098a0 331 Hamap MF_01004 Vitamin B12 import system permease protein BtuC [btuC]. 3 329 29.449 T 05-07-2017 IPR023691 ABC transporter, vitamin B12 import, permease protein BtuC GO:0015889|GO:0016020 K08M4_RS06580 a6d0f0d69a9bbade1e2f60df8d2098a0 331 Pfam PF01032 FecCD transport family 24 326 2.4E-80 T 05-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 K08M4_RS06580 a6d0f0d69a9bbade1e2f60df8d2098a0 331 SUPERFAMILY SSF81345 7 327 8.11E-79 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS06580 a6d0f0d69a9bbade1e2f60df8d2098a0 331 Gene3D G3DSA:1.10.3470.10 8 327 2.1E-93 T 05-07-2017 IPR029022 ABC transporter, BtuC-like K08M4_RS14480 1291246c745983c3a293c32e64bdcc61 108 SUPERFAMILY SSF47413 4 75 1.77E-15 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS14480 1291246c745983c3a293c32e64bdcc61 108 SMART SM00530 10 69 4.3E-13 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 K08M4_RS14480 1291246c745983c3a293c32e64bdcc61 108 Pfam PF12844 Helix-turn-helix domain 10 70 2.9E-14 T 05-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 K08M4_RS14480 1291246c745983c3a293c32e64bdcc61 108 Gene3D G3DSA:1.10.260.40 2 78 4.7E-22 T 05-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 K08M4_RS11295 120ec5a7527c28367366f77224b37474 41 SUPERFAMILY SSF57840 5 40 2.09E-13 T 05-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS11295 120ec5a7527c28367366f77224b37474 41 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 8.7E-7 T 05-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS11295 120ec5a7527c28367366f77224b37474 41 ProSitePatterns PS00828 Ribosomal protein L36 signature. 14 40 - T 05-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS11295 120ec5a7527c28367366f77224b37474 41 Pfam PF00444 Ribosomal protein L36 1 40 6.8E-16 T 05-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS11295 120ec5a7527c28367366f77224b37474 41 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 41 15.816 T 05-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 K08M4_RS00740 eba813a478a65e62e95e784e7e1022b9 111 Pfam PF13358 DDE superfamily endonuclease 5 85 1.4E-14 T 05-07-2017 K08M4_RS09000 7f67921137bcdba776f3bd1c32017d5c 266 Pfam PF11201 Protein of unknown function (DUF2982) 67 166 6.4E-34 T 05-07-2017 IPR021367 Protein of unknown function DUF2982 K08M4_RS09000 7f67921137bcdba776f3bd1c32017d5c 266 Pfam PF11201 Protein of unknown function (DUF2982) 194 259 7.0E-13 T 05-07-2017 IPR021367 Protein of unknown function DUF2982 K08M4_RS21535 bed03882ab0b97dee507a9d98da61a8b 654 Pfam PF01757 Acyltransferase family 6 321 1.3E-25 T 05-07-2017 IPR002656 Acyltransferase 3 GO:0016747 K08M4_RS18715 37c7f5177a237f47187538bcb41e3212 302 Gene3D G3DSA:1.10.10.10 2 80 1.4E-20 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS18715 37c7f5177a237f47187538bcb41e3212 302 SUPERFAMILY SSF46785 4 82 9.8E-17 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS18715 37c7f5177a237f47187538bcb41e3212 302 Gene3D G3DSA:3.40.190.10 219 256 1.3E-4 T 05-07-2017 K08M4_RS18715 37c7f5177a237f47187538bcb41e3212 302 SUPERFAMILY SSF53850 94 297 1.81E-12 T 05-07-2017 K08M4_RS18715 37c7f5177a237f47187538bcb41e3212 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 8.2E-14 T 05-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 K08M4_RS18715 37c7f5177a237f47187538bcb41e3212 302 Pfam PF03466 LysR substrate binding domain 94 261 6.4E-11 T 05-07-2017 IPR005119 LysR, substrate-binding K08M4_RS18715 37c7f5177a237f47187538bcb41e3212 302 Gene3D G3DSA:3.40.190.10 95 216 2.4E-5 T 05-07-2017 K08M4_RS20095 337be9d639ec8835d0fd1e7bc6dd7885 329 Pfam PF06616 BsuBI/PstI restriction endonuclease C-terminus 14 323 1.1E-117 T 05-07-2017 IPR009528 Restriction endonuclease, type II, BsuBI/PstI, C-terminal GO:0000287|GO:0003677|GO:0009036|GO:0009307 K08M4_RS00095 cec7b48d4676f0987382cd143b3573f1 175 Pfam PF12724 Flavodoxin domain 5 153 2.0E-50 T 05-07-2017 IPR026816 Flavodoxin domain K08M4_RS00095 cec7b48d4676f0987382cd143b3573f1 175 SUPERFAMILY SSF52218 3 158 1.55E-31 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS00095 cec7b48d4676f0987382cd143b3573f1 175 Gene3D G3DSA:3.40.50.360 3 72 5.4E-23 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS00095 cec7b48d4676f0987382cd143b3573f1 175 Gene3D G3DSA:3.40.50.360 106 172 5.4E-23 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS10515 6d8adfeba684cce69e53e928304521ee 142 PIRSF PIRSF000714 2 140 7.7E-53 T 05-07-2017 IPR026026 Histidine triad hydrolase, Hint-type K08M4_RS10515 6d8adfeba684cce69e53e928304521ee 142 Pfam PF01230 HIT domain 11 99 2.3E-18 T 05-07-2017 IPR001310 Histidine triad (HIT) protein K08M4_RS10515 6d8adfeba684cce69e53e928304521ee 142 Gene3D G3DSA:3.30.428.10 2 134 2.7E-38 T 05-07-2017 IPR011146 HIT-like domain GO:0003824 K08M4_RS10515 6d8adfeba684cce69e53e928304521ee 142 SUPERFAMILY SSF54197 3 133 1.15E-34 T 05-07-2017 IPR011146 HIT-like domain GO:0003824 K08M4_RS05180 924219d2580b62f1fb8f9fd2af91512f 197 Pfam PF13505 Outer membrane protein beta-barrel domain 9 195 1.1E-7 T 05-07-2017 IPR027385 Outer membrane protein beta-barrel K08M4_RS05180 924219d2580b62f1fb8f9fd2af91512f 197 Gene3D G3DSA:2.40.160.20 47 197 1.5E-16 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS05180 924219d2580b62f1fb8f9fd2af91512f 197 SUPERFAMILY SSF56925 32 197 4.97E-17 T 05-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 K08M4_RS18385 eea3983b921c2999d80cbf776ba6232b 158 Pfam PF04143 Sulphur transport 5 142 8.3E-10 T 05-07-2017 IPR007272 Sulphur transport domain K08M4_RS07630 8266c7237ca1cb02fb008c46a48ad724 224 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 8 211 3.1E-56 T 05-07-2017 K08M4_RS01645 b3e411e7dc0956963003d2c8d0acf708 180 SUPERFAMILY SSF109854 26 163 4.35E-5 T 05-07-2017 K08M4_RS17270 33e1a024d613d768f70bda3d0e685aac 304 Pfam PF00482 Type II secretion system (T2SS), protein F 137 261 1.6E-16 T 05-07-2017 IPR018076 Type II secretion system F domain K08M4_RS11595 2f1009fee2a8988983f576b6c55119b2 316 Pfam PF03595 Voltage-dependent anion channel 4 295 3.6E-30 T 05-07-2017 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 K08M4_RS18755 9eabb70c5c41e09fe036a7c61a7c82e3 70 Pfam PF07869 Protein of unknown function (DUF1656) 7 62 4.4E-14 T 05-07-2017 IPR012451 Protein of unknown function DUF1656 K08M4_RS08135 ccd3aeb890d063cabaf5daae5bba72b9 169 SUPERFAMILY SSF54637 64 160 2.79E-21 T 05-07-2017 IPR029069 HotDog domain K08M4_RS08135 ccd3aeb890d063cabaf5daae5bba72b9 169 SUPERFAMILY SSF54637 5 33 2.79E-21 T 05-07-2017 IPR029069 HotDog domain K08M4_RS08135 ccd3aeb890d063cabaf5daae5bba72b9 169 Gene3D G3DSA:3.10.129.10 6 161 9.9E-20 T 05-07-2017 IPR029069 HotDog domain K08M4_RS08135 ccd3aeb890d063cabaf5daae5bba72b9 169 Pfam PF03061 Thioesterase superfamily 80 145 1.7E-5 T 05-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 K08M4_RS18775 df6206a827f033e67f391d2bc6224e64 685 Gene3D G3DSA:3.40.50.1820 439 646 9.6E-81 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS18775 df6206a827f033e67f391d2bc6224e64 685 Gene3D G3DSA:3.40.50.1820 70 359 9.6E-81 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS18775 df6206a827f033e67f391d2bc6224e64 685 Pfam PF00135 Carboxylesterase family 69 644 3.3E-60 T 05-07-2017 IPR002018 Carboxylesterase, type B K08M4_RS18775 df6206a827f033e67f391d2bc6224e64 685 SUPERFAMILY SSF53474 500 631 3.1E-58 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS18775 df6206a827f033e67f391d2bc6224e64 685 SUPERFAMILY SSF53474 74 433 3.1E-58 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS06500 77e0b599a272f22dfa4bb88a82e94f26 123 Pfam PF03788 LrgA family 23 114 1.5E-24 T 05-07-2017 IPR005538 LrgA/CidA family GO:0016021 K08M4_RS20695 5140bd0ee89eccbd7aa18e430866787e 174 Pfam PF11286 Protein of unknown function (DUF3087) 2 170 1.0E-55 T 05-07-2017 IPR021438 Protein of unknown function DUF3087 K08M4_RS01855 202721a7d7ae9e87baabaeba6c9b244b 163 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 4 152 1.3E-55 T 05-07-2017 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 K08M4_RS01855 202721a7d7ae9e87baabaeba6c9b244b 163 Pfam PF02470 MlaD protein 40 118 1.8E-20 T 05-07-2017 IPR003399 Mce/MlaD K08M4_RS04820 62f14b334af64c783570d84c89aa7a20 112 Gene3D G3DSA:3.40.30.10 7 102 4.9E-31 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS04820 62f14b334af64c783570d84c89aa7a20 112 Pfam PF00462 Glutaredoxin 16 80 7.6E-17 T 05-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 K08M4_RS04820 62f14b334af64c783570d84c89aa7a20 112 SUPERFAMILY SSF52833 1 104 4.63E-33 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS04820 62f14b334af64c783570d84c89aa7a20 112 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 4 100 1.5E-45 T 05-07-2017 IPR004480 Monothiol glutaredoxin-related K08M4_RS04820 62f14b334af64c783570d84c89aa7a20 112 PIRSF PIRSF005894 1 107 1.3E-51 T 05-07-2017 IPR014434 Monothiol glutaredoxin K08M4_RS03830 b15570c042c9d5a4c32795c99a820ca6 283 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 18 275 4.0E-116 T 05-07-2017 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 K08M4_RS03830 b15570c042c9d5a4c32795c99a820ca6 283 Gene3D G3DSA:3.20.20.70 16 278 2.4E-107 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS03830 b15570c042c9d5a4c32795c99a820ca6 283 SUPERFAMILY SSF51569 2 279 7.6E-105 T 05-07-2017 K08M4_RS03830 b15570c042c9d5a4c32795c99a820ca6 283 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 13 277 48.473 T 05-07-2017 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 K08M4_RS03830 b15570c042c9d5a4c32795c99a820ca6 283 Pfam PF00793 DAHP synthetase I family 12 274 3.5E-70 T 05-07-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 K08M4_RS04390 7891612c86ae44ba3fee8bf744e743e3 485 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 7 453 9.9E-151 T 05-07-2017 IPR003846 Uncharacterised protein family UPF0061 K08M4_RS04390 7891612c86ae44ba3fee8bf744e743e3 485 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 5 471 43.904 T 05-07-2017 IPR003846 Uncharacterised protein family UPF0061 K08M4_RS07135 4e817f1293a265546e279a6579b5b00d 127 SUPERFAMILY SSF54427 1 123 6.27E-32 T 05-07-2017 IPR032710 NTF2-like domain K08M4_RS07135 4e817f1293a265546e279a6579b5b00d 127 Pfam PF12680 SnoaL-like domain 9 101 7.7E-11 T 05-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain K08M4_RS07135 4e817f1293a265546e279a6579b5b00d 127 Gene3D G3DSA:3.10.450.50 2 107 4.8E-16 T 05-07-2017 IPR032710 NTF2-like domain K08M4_RS19155 8f677c9bb46ce46e42bdda9a948d2e99 120 SUPERFAMILY SSF47226 2 109 5.89E-5 T 05-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 K08M4_RS07065 9db744670b39ee8b6a319d9e7bcc5354 282 SUPERFAMILY SSF51735 11 232 1.12E-17 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS07065 9db744670b39ee8b6a319d9e7bcc5354 282 Gene3D G3DSA:3.40.50.720 10 226 2.9E-13 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS14945 c1f93c854f0ea1182a2c17904ce2eac3 129 Pfam PF03899 ATP synthase I chain 15 111 3.3E-17 T 05-07-2017 IPR005598 ATP synthase protein I K08M4_RS01655 45b460d46aedc9a61216e0fc15021199 195 Pfam PF09335 SNARE associated Golgi protein 40 153 9.0E-12 T 05-07-2017 IPR032816 SNARE associated Golgi protein K08M4_RS04010 d177a67b5ab2fbee4aed01a46076648b 143 Pfam PF02169 LPP20 lipoprotein 28 118 6.3E-9 T 05-07-2017 IPR024952 Lipoprotein LPP20-like K08M4_RS04010 d177a67b5ab2fbee4aed01a46076648b 143 PIRSF PIRSF028687 1 143 7.2E-59 T 05-07-2017 IPR007293 Flagellar protein FlgP K08M4_RS06735 4c0d2a54e51f84555f318b2b86d946ae 220 Pfam PF11726 Protein of unknown function (DUF3296) 30 218 2.6E-50 T 05-07-2017 IPR021723 Inovirus Gp2 K08M4_RS11435 49329337bc3f2af6b65c6c46d337a21f 264 Pfam PF11101 Protein of unknown function (DUF2884) 38 262 3.5E-73 T 05-07-2017 IPR021307 Protein of unknown function DUF2884 K08M4_RS06305 fc754bd81f75edb19a67573322673db6 472 PIRSF PIRSF002457 1 472 4.9E-116 T 05-07-2017 IPR030676 Citrate carrier CitT-related K08M4_RS06305 fc754bd81f75edb19a67573322673db6 472 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 35 462 7.1E-80 T 05-07-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 K08M4_RS06305 fc754bd81f75edb19a67573322673db6 472 Pfam PF00939 Sodium:sulfate symporter transmembrane region 5 462 1.7E-50 T 05-07-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 K08M4_RS14955 df6666b08dcf31acda440bf0c07b2e83 259 Pfam PF13614 AAA domain 2 178 5.9E-63 T 05-07-2017 IPR025669 AAA domain K08M4_RS14955 df6666b08dcf31acda440bf0c07b2e83 259 Gene3D G3DSA:3.40.50.300 3 254 5.1E-72 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS14955 df6666b08dcf31acda440bf0c07b2e83 259 SUPERFAMILY SSF52540 2 254 2.67E-67 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS18805 8f8ea11858445256f58fc0c3af959038 313 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 2 305 7.5E-104 T 05-07-2017 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 K08M4_RS18805 8f8ea11858445256f58fc0c3af959038 313 Pfam PF03741 Integral membrane protein TerC family 73 274 3.8E-53 T 05-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 K08M4_RS20580 7ae9a07debeef239f0e44b8f53c09d4c 277 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 7 276 66.746 T 05-07-2017 IPR026530 Phosphoenolpyruvate synthase regulatory protein K08M4_RS20580 7ae9a07debeef239f0e44b8f53c09d4c 277 Pfam PF03618 Kinase/pyrophosphorylase 10 267 6.2E-72 T 05-07-2017 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 K08M4_RS21015 21f101f0e6571f97a523eb10e552af87 236 SUPERFAMILY SSF53187 15 106 1.29E-29 T 05-07-2017 K08M4_RS21015 21f101f0e6571f97a523eb10e552af87 236 SUPERFAMILY SSF53187 133 213 1.29E-29 T 05-07-2017 K08M4_RS21015 21f101f0e6571f97a523eb10e552af87 236 Gene3D G3DSA:3.40.630.10 17 229 7.5E-37 T 05-07-2017 K08M4_RS21015 21f101f0e6571f97a523eb10e552af87 236 Pfam PF00246 Zinc carboxypeptidase 37 157 6.6E-12 T 05-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 K08M4_RS13155 12659eca81b7cc1b50f6d46c58feb220 407 Pfam PF00482 Type II secretion system (T2SS), protein F 72 195 6.1E-28 T 05-07-2017 IPR018076 Type II secretion system F domain K08M4_RS13155 12659eca81b7cc1b50f6d46c58feb220 407 Pfam PF00482 Type II secretion system (T2SS), protein F 275 397 2.3E-26 T 05-07-2017 IPR018076 Type II secretion system F domain K08M4_RS13155 12659eca81b7cc1b50f6d46c58feb220 407 PRINTS PR00812 Bacterial general secretion pathway protein F signature 68 80 2.5E-8 T 05-07-2017 IPR003004 GspF/PilC family K08M4_RS13155 12659eca81b7cc1b50f6d46c58feb220 407 PRINTS PR00812 Bacterial general secretion pathway protein F signature 386 405 2.5E-8 T 05-07-2017 IPR003004 GspF/PilC family K08M4_RS13155 12659eca81b7cc1b50f6d46c58feb220 407 PRINTS PR00812 Bacterial general secretion pathway protein F signature 167 195 2.5E-8 T 05-07-2017 IPR003004 GspF/PilC family K08M4_RS13155 12659eca81b7cc1b50f6d46c58feb220 407 PRINTS PR00812 Bacterial general secretion pathway protein F signature 370 384 2.5E-8 T 05-07-2017 IPR003004 GspF/PilC family K08M4_RS12765 dd9590bb04d8596cbc61cd928f3db10f 420 Pfam PF01384 Phosphate transporter family 26 407 2.7E-119 T 05-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 K08M4_RS14375 6d820c2cf2d5835c4b2e14b247b8075b 146 Gene3D G3DSA:3.40.630.30 9 145 6.4E-15 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS14375 6d820c2cf2d5835c4b2e14b247b8075b 146 SUPERFAMILY SSF55729 1 134 7.93E-14 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS11465 231decf8aa7e719100d5bb7d51a81659 334 SUPERFAMILY SSF143631 23 332 2.88E-101 T 05-07-2017 IPR003374 ApbE-like domain K08M4_RS11465 231decf8aa7e719100d5bb7d51a81659 334 Pfam PF02424 ApbE family 31 310 2.3E-85 T 05-07-2017 IPR024932 Flavin transferase ApbE GO:0017013 K08M4_RS11465 231decf8aa7e719100d5bb7d51a81659 334 PIRSF PIRSF006268 1 332 5.1E-95 T 05-07-2017 IPR024932 Flavin transferase ApbE GO:0017013 K08M4_RS13805 01efd8d1e66e1dec48fd70734e1e0dfe 134 Pfam PF04138 GtrA-like protein 20 131 1.0E-17 T 05-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 K08M4_RS01290 2ac675c8bb2a69ee99c5b6d913ed6191 505 Gene3D G3DSA:3.40.50.300 28 158 2.0E-6 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01290 2ac675c8bb2a69ee99c5b6d913ed6191 505 Pfam PF13401 AAA domain 31 154 1.1E-8 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS01290 2ac675c8bb2a69ee99c5b6d913ed6191 505 SUPERFAMILY SSF52540 17 224 2.96E-9 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15400 3dbec7e46c422c4f1bfe14e309911fba 336 Gene3D G3DSA:3.40.50.720 4 154 2.6E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS15400 3dbec7e46c422c4f1bfe14e309911fba 336 SUPERFAMILY SSF55347 149 298 2.62E-15 T 05-07-2017 K08M4_RS15400 3dbec7e46c422c4f1bfe14e309911fba 336 SUPERFAMILY SSF51735 5 144 8.18E-37 T 05-07-2017 IPR016040 NAD(P)-binding domain K08M4_RS15400 3dbec7e46c422c4f1bfe14e309911fba 336 Gene3D G3DSA:3.30.360.10 155 327 1.4E-22 T 05-07-2017 K08M4_RS15400 3dbec7e46c422c4f1bfe14e309911fba 336 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 124 5.1E-23 T 05-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 K08M4_RS18765 56470b70059c546c5ba9a8e002b25c8d 453 Pfam PF04632 Fusaric acid resistance protein family 9 211 4.4E-33 T 05-07-2017 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 K08M4_RS09080 141acb9009db8ff6c3cda008beef16e1 114 Pfam PF00581 Rhodanese-like domain 29 106 3.8E-15 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS09080 141acb9009db8ff6c3cda008beef16e1 114 Gene3D G3DSA:3.40.250.10 28 109 1.0E-26 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS09080 141acb9009db8ff6c3cda008beef16e1 114 SUPERFAMILY SSF52821 29 109 1.96E-26 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS09080 141acb9009db8ff6c3cda008beef16e1 114 SMART SM00450 22 114 1.7E-18 T 05-07-2017 IPR001763 Rhodanese-like domain K08M4_RS10055 5393a89f42ec631eb69e9653c9382709 433 Gene3D G3DSA:3.40.50.1820 199 411 1.6E-28 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS10055 5393a89f42ec631eb69e9653c9382709 433 SUPERFAMILY SSF53474 196 405 1.82E-25 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS10055 5393a89f42ec631eb69e9653c9382709 433 Pfam PF12695 Alpha/beta hydrolase family 203 282 1.1E-8 T 05-07-2017 IPR029059 Alpha/beta hydrolase fold-5 K08M4_RS04765 baf8e590d25c12cb2b6bd739f19ef223 334 Hamap MF_00730 Nucleoid-associated protein YejK [yejK]. 3 332 46.245 T 05-07-2017 IPR007358 Nucleoid-associated protein NdpA GO:0009295 K08M4_RS04765 baf8e590d25c12cb2b6bd739f19ef223 334 Pfam PF04245 37-kD nucleoid-associated bacterial protein 9 326 2.1E-97 T 05-07-2017 IPR007358 Nucleoid-associated protein NdpA GO:0009295 K08M4_RS17565 f022ef6bf74a520a776a3c1be4519257 314 SUPERFAMILY SSF101478 2 303 5.62E-37 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 K08M4_RS17565 f022ef6bf74a520a776a3c1be4519257 314 Pfam PF03747 ADP-ribosylglycohydrolase 11 287 5.0E-50 T 05-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 K08M4_RS06495 6dee6d226e0547d16db299cc44a0c141 225 Pfam PF04172 LrgB-like family 6 218 7.8E-73 T 05-07-2017 IPR007300 CidB/LrgB family K08M4_RS08270 d412a735bc8f92b01305960cbdba2051 605 Pfam PF10592 AIPR protein 259 485 4.5E-43 T 05-07-2017 IPR018891 Abortive bacteriophage infection, resistance K08M4_RS05425 ee02652192ef0e226e9e30eb2d5ecae2 105 ProSitePatterns PS01358 Zinc finger RanBP2-type signature. 80 99 - T 05-07-2017 IPR001876 Zinc finger, RanBP2-type GO:0008270 K08M4_RS05425 ee02652192ef0e226e9e30eb2d5ecae2 105 Pfam PF09413 Putative prokaryotic signal transducing protein 2 68 1.4E-9 T 05-07-2017 IPR018551 Domain of unknown function DUF2007 K08M4_RS19920 75c25016d6f02af0a446959436db943e 506 Pfam PF12571 Phage tail-collar fibre protein 4 153 7.2E-15 T 05-07-2017 IPR022225 Phage tail fibre protein K08M4_RS19920 75c25016d6f02af0a446959436db943e 506 SUPERFAMILY SSF88874 356 505 4.71E-5 T 05-07-2017 K08M4_RS04300 3e63615058418f96b1a3e678ef243bf7 68 Pfam PF04995 Heme exporter protein D (CcmD) 13 56 7.3E-18 T 05-07-2017 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 K08M4_RS04300 3e63615058418f96b1a3e678ef243bf7 68 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 10 56 6.1E-19 T 05-07-2017 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 K08M4_RS20855 0b947ebcabe8d6a790dfa2f06e19e5b0 406 SUPERFAMILY SSF51695 64 399 1.73E-65 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 K08M4_RS20855 0b947ebcabe8d6a790dfa2f06e19e5b0 406 Gene3D G3DSA:3.20.20.190 64 396 4.0E-60 T 05-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 K08M4_RS20855 0b947ebcabe8d6a790dfa2f06e19e5b0 406 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 66 393 5.8E-25 T 05-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 K08M4_RS01735 29845a60b683e51c1c3cbd89ecf521b7 1252 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 919 1251 9.2E-61 T 05-07-2017 IPR007452 Translocation and assembly module TamB K08M4_RS20480 b779817f21ac963adca7de69a3850440 254 SUPERFAMILY SSF56529 5 250 9.16E-36 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 K08M4_RS20480 b779817f21ac963adca7de69a3850440 254 Gene3D G3DSA:3.90.850.10 6 251 5.8E-46 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 K08M4_RS15605 e62f85cac932c828898d6e12a6987e25 215 Gene3D G3DSA:3.40.30.10 2 211 4.0E-42 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS15605 e62f85cac932c828898d6e12a6987e25 215 Pfam PF01323 DSBA-like thioredoxin domain 7 209 5.4E-31 T 05-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 K08M4_RS15605 e62f85cac932c828898d6e12a6987e25 215 SUPERFAMILY SSF52833 3 214 2.51E-43 T 05-07-2017 IPR012336 Thioredoxin-like fold K08M4_RS10940 2ecf3954a5e87850487331509fdfdcf1 114 Pfam PF11169 Protein of unknown function (DUF2956) 9 113 6.2E-41 T 05-07-2017 IPR021339 Protein of unknown function DUF2956 K08M4_RS07610 dfd0ac582c08fbc9a82c5e516c750df8 216 Pfam PF11205 Protein of unknown function (DUF2987) 22 164 3.1E-51 T 05-07-2017 IPR021370 Protein of unknown function DUF2987 K08M4_RS01355 6104d9e9cd97d84c47370e041509838d 289 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 214 4.5E-71 T 05-07-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 K08M4_RS01355 6104d9e9cd97d84c47370e041509838d 289 Gene3D G3DSA:3.40.50.300 1 288 3.2E-127 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01355 6104d9e9cd97d84c47370e041509838d 289 SUPERFAMILY SSF52540 4 286 1.61E-47 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS01355 6104d9e9cd97d84c47370e041509838d 289 PRINTS PR00478 Phosphoribulokinase family signature 164 181 8.3E-27 T 05-07-2017 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 K08M4_RS01355 6104d9e9cd97d84c47370e041509838d 289 PRINTS PR00478 Phosphoribulokinase family signature 12 29 8.3E-27 T 05-07-2017 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 K08M4_RS01355 6104d9e9cd97d84c47370e041509838d 289 PRINTS PR00478 Phosphoribulokinase family signature 182 205 8.3E-27 T 05-07-2017 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 K08M4_RS01355 6104d9e9cd97d84c47370e041509838d 289 PRINTS PR00478 Phosphoribulokinase family signature 126 144 8.3E-27 T 05-07-2017 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 K08M4_RS01685 870afda5039ababd2a47e9ceeb305f56 302 TIGRFAM TIGR03899 TIGR03899: TIGR03899 family protein 37 290 1.3E-104 T 05-07-2017 IPR021254 Protein of unknown function DUF2806 K08M4_RS01685 870afda5039ababd2a47e9ceeb305f56 302 Pfam PF10987 Protein of unknown function (DUF2806) 62 280 3.7E-83 T 05-07-2017 IPR021254 Protein of unknown function DUF2806 K08M4_RS05845 a37010a6add653dffdc786e991a11ee2 208 Pfam PF01810 LysE type translocator 15 205 2.4E-36 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS05845 a37010a6add653dffdc786e991a11ee2 208 PIRSF PIRSF006324 1 207 9.7E-49 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS21420 77b77a1241cbb6ac7c125587c4bc4ff4 346 Pfam PF01757 Acyltransferase family 13 331 2.1E-23 T 05-07-2017 IPR002656 Acyltransferase 3 GO:0016747 K08M4_RS05725 596dd0eaad9ed58a612ea9f98af10895 131 Pfam PF16549 Type II secretion system (T2SS) pilotin, S protein 13 129 7.9E-50 T 05-07-2017 IPR016502 Type II secretion system (T2SS) pilotin, S protein K08M4_RS05725 596dd0eaad9ed58a612ea9f98af10895 131 PIRSF PIRSF007010 1 131 5.5E-50 T 05-07-2017 IPR016502 Type II secretion system (T2SS) pilotin, S protein K08M4_RS10115 14f9c347cad434bab37acebd296b58c7 256 Gene3D G3DSA:3.20.20.370 1 253 1.2E-68 T 05-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 K08M4_RS10115 14f9c347cad434bab37acebd296b58c7 256 SUPERFAMILY SSF88713 1 253 1.42E-66 T 05-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 K08M4_RS10115 14f9c347cad434bab37acebd296b58c7 256 Pfam PF04794 YdjC-like protein 2 241 1.5E-51 T 05-07-2017 IPR006879 Chitooligosaccharide deacetylase ChbG-like K08M4_RS21820 de4affc9db02dca133a233462f433015 345 Gene3D G3DSA:3.90.850.10 312 323 6.0E-39 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 K08M4_RS21820 de4affc9db02dca133a233462f433015 345 Gene3D G3DSA:3.90.850.10 76 276 6.0E-39 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 K08M4_RS21820 de4affc9db02dca133a233462f433015 345 SUPERFAMILY SSF56529 83 340 2.14E-54 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 K08M4_RS21820 de4affc9db02dca133a233462f433015 345 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 88 339 6.8E-39 T 05-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 K08M4_RS08145 7abae7d7a24d88d9563561ab04721eb2 65 Pfam PF04400 Protein of unknown function (DUF539) 21 62 2.0E-20 T 05-07-2017 IPR007495 (Na+)-NQR maturation factor NqrM K08M4_RS21035 435b23dafddb9cf3c8f6e94a288bdd15 279 Pfam PF00756 Putative esterase 23 272 3.9E-56 T 05-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 K08M4_RS21035 435b23dafddb9cf3c8f6e94a288bdd15 279 SUPERFAMILY SSF53474 3 278 2.58E-89 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS21035 435b23dafddb9cf3c8f6e94a288bdd15 279 Gene3D G3DSA:3.40.50.1820 3 278 2.4E-72 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS21035 435b23dafddb9cf3c8f6e94a288bdd15 279 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 5 276 5.1E-118 T 05-07-2017 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 K08M4_RS16775 e34c5530f25495e94e3bf86ccccf1b8d 72 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 4 68 2.9E-31 T 05-07-2017 IPR024530 Putative quorum-sensing-regulated virulence factor K08M4_RS16775 e34c5530f25495e94e3bf86ccccf1b8d 72 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 15 68 6.0E-22 T 05-07-2017 IPR024530 Putative quorum-sensing-regulated virulence factor K08M4_RS14410 03e2d6b0ce082751da6a11ad9850b5ef 201 SUPERFAMILY SSF55718 28 118 1.86E-9 T 05-07-2017 IPR003033 SCP2 sterol-binding domain K08M4_RS14410 03e2d6b0ce082751da6a11ad9850b5ef 201 Gene3D G3DSA:3.30.1050.10 33 113 3.1E-6 T 05-07-2017 IPR003033 SCP2 sterol-binding domain K08M4_RS14410 03e2d6b0ce082751da6a11ad9850b5ef 201 Pfam PF02036 SCP-2 sterol transfer family 16 111 5.9E-23 T 05-07-2017 IPR003033 SCP2 sterol-binding domain K08M4_RS16290 dd419e8af4f7e594d487e5d54078613a 173 Pfam PF01467 Cytidylyltransferase-like 6 142 4.5E-6 T 05-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 K08M4_RS16290 dd419e8af4f7e594d487e5d54078613a 173 Gene3D G3DSA:3.40.50.620 1 171 1.3E-41 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS16290 dd419e8af4f7e594d487e5d54078613a 173 SUPERFAMILY SSF52374 1 170 4.38E-24 T 05-07-2017 K08M4_RS19325 4bedc475a46be84477cee8ae0b62b7a6 341 Pfam PF00990 Diguanylate cyclase, GGDEF domain 205 299 3.4E-11 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS19325 4bedc475a46be84477cee8ae0b62b7a6 341 SUPERFAMILY SSF55073 209 317 1.1E-11 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS19325 4bedc475a46be84477cee8ae0b62b7a6 341 Gene3D G3DSA:3.30.70.270 205 303 6.2E-11 T 05-07-2017 K08M4_RS19440 72ce55907c65911ff3c2a9be7eea9b89 139 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 139 32.511 T 05-07-2017 IPR023064 D-ribose pyranase GO:0016872 K08M4_RS19440 72ce55907c65911ff3c2a9be7eea9b89 139 SUPERFAMILY SSF102546 1 139 1.11E-43 T 05-07-2017 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 K08M4_RS19440 72ce55907c65911ff3c2a9be7eea9b89 139 Gene3D G3DSA:3.40.1650.10 1 139 2.9E-38 T 05-07-2017 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 K08M4_RS19440 72ce55907c65911ff3c2a9be7eea9b89 139 Pfam PF05025 RbsD / FucU transport protein family 1 138 2.0E-47 T 05-07-2017 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 K08M4_RS10035 e895183e4fd804dd85d950c143232b72 318 SUPERFAMILY SSF48008 160 292 1.49E-13 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS10035 e895183e4fd804dd85d950c143232b72 318 Pfam PF07729 FCD domain 163 285 2.3E-9 T 05-07-2017 IPR011711 GntR, C-terminal K08M4_RS10035 e895183e4fd804dd85d950c143232b72 318 Gene3D G3DSA:1.10.10.10 16 70 4.7E-11 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS10035 e895183e4fd804dd85d950c143232b72 318 SUPERFAMILY SSF46785 16 71 5.56E-7 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS10035 e895183e4fd804dd85d950c143232b72 318 SMART SM00895 162 286 2.7E-7 T 05-07-2017 IPR011711 GntR, C-terminal K08M4_RS10035 e895183e4fd804dd85d950c143232b72 318 Gene3D G3DSA:1.20.120.530 161 294 5.2E-12 T 05-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal K08M4_RS10035 e895183e4fd804dd85d950c143232b72 318 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 68 4.5E-9 T 05-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 K08M4_RS08975 9f52748d3f5e41a8554f3bddefa67cb5 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 423 2.9E-104 T 05-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 K08M4_RS08975 9f52748d3f5e41a8554f3bddefa67cb5 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 9 422 1.0E-99 T 05-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit K08M4_RS08975 9f52748d3f5e41a8554f3bddefa67cb5 427 PIRSF PIRSF006066 1 426 1.5E-72 T 05-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 K08M4_RS16440 5be8f6375352e1d7d9cdbe7359d50c11 401 Pfam PF07690 Major Facilitator Superfamily 22 354 1.3E-42 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS16440 5be8f6375352e1d7d9cdbe7359d50c11 401 Gene3D G3DSA:1.20.1250.20 212 386 3.5E-10 T 05-07-2017 K08M4_RS16440 5be8f6375352e1d7d9cdbe7359d50c11 401 Gene3D G3DSA:1.20.1250.20 8 188 5.7E-27 T 05-07-2017 K08M4_RS16440 5be8f6375352e1d7d9cdbe7359d50c11 401 SUPERFAMILY SSF103473 7 389 3.53E-55 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS16440 5be8f6375352e1d7d9cdbe7359d50c11 401 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 11 375 5.6E-60 T 05-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 K08M4_RS10420 1f7f47b02f64db91856c40275ab6f217 331 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 33 277 1.1E-80 T 05-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 K08M4_RS10420 1f7f47b02f64db91856c40275ab6f217 331 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 33 317 1.8E-104 T 05-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 K08M4_RS10420 1f7f47b02f64db91856c40275ab6f217 331 PIRSF PIRSF006470 1 331 9.8E-126 T 05-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 K08M4_RS02205 fa0f873548b561b4b38818bbfc6f53db 265 Pfam PF09955 Predicted integral membrane protein (DUF2189) 82 195 1.6E-25 T 05-07-2017 IPR018692 Predicted integral membrane protein DUF2189 K08M4_RS17760 2c58b3dd75a573c69642c3033713834f 113 Pfam PF04320 Protein with unknown function (DUF469) 11 111 4.5E-33 T 05-07-2017 IPR007416 Protein of unknown function DUF469 K08M4_RS15890 e23424f7ea056d62a804dd1a863fca3a 279 Pfam PF02361 Cobalt transport protein 16 237 2.1E-30 T 05-07-2017 IPR003339 ABC/ECF transporter, transmembrane component K08M4_RS21175 93913eb8206b4e99d5919d01b96af685 393 Pfam PF07690 Major Facilitator Superfamily 16 345 1.2E-14 T 05-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 K08M4_RS21175 93913eb8206b4e99d5919d01b96af685 393 SUPERFAMILY SSF103473 14 381 1.1E-38 T 05-07-2017 IPR020846 Major facilitator superfamily domain K08M4_RS21175 93913eb8206b4e99d5919d01b96af685 393 Gene3D G3DSA:1.20.1250.20 203 382 9.7E-18 T 05-07-2017 K08M4_RS21175 93913eb8206b4e99d5919d01b96af685 393 Gene3D G3DSA:1.20.1250.20 15 197 1.2E-11 T 05-07-2017 K08M4_RS10945 7a9d0b8cdcc899cde3fdd2d31b82ee62 110 Pfam PF13698 Domain of unknown function (DUF4156) 24 109 1.5E-18 T 05-07-2017 IPR025294 Protein of unknown function DUF4156 K08M4_RS12205 0de0c7e5b30f27253c55fb786777470e 116 Pfam PF10973 Protein of unknown function (DUF2799) 29 109 7.1E-23 T 05-07-2017 IPR021242 Protein of unknown function DUF2799 K08M4_RS06475 8663057127bb66d4b37189d901ca6b76 258 Gene3D G3DSA:3.30.460.10 101 190 5.7E-6 T 05-07-2017 K08M4_RS06475 8663057127bb66d4b37189d901ca6b76 258 SUPERFAMILY SSF81301 64 220 5.07E-14 T 05-07-2017 K08M4_RS20135 7141f29f0b86ac8b984af9b4499a1f39 450 Pfam PF01554 MatE 238 401 1.5E-18 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS20135 7141f29f0b86ac8b984af9b4499a1f39 450 Pfam PF01554 MatE 10 174 1.7E-18 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS20135 7141f29f0b86ac8b984af9b4499a1f39 450 TIGRFAM TIGR00797 matE: MATE efflux family protein 10 413 6.9E-51 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS01045 386d26bb68327e108c14c600a2c3f966 174 Pfam PF04186 FxsA cytoplasmic membrane protein 7 113 2.5E-35 T 05-07-2017 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 K08M4_RS10810 bee8a012d0dfdbc907efd20ac980f4ab 386 Pfam PF14279 HNH endonuclease 22 74 1.1E-14 T 05-07-2017 IPR029471 HNH endonuclease 5 K08M4_RS19345 4eb8a92952d4658e2116a32b5738b5ca 204 SUPERFAMILY SSF46626 18 195 7.35E-25 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19345 4eb8a92952d4658e2116a32b5738b5ca 204 Gene3D G3DSA:1.10.760.10 15 195 4.2E-27 T 05-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 K08M4_RS19345 4eb8a92952d4658e2116a32b5738b5ca 204 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 9 181 3.0E-60 T 05-07-2017 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO K08M4_RS10235 f62e12ba2180b61b3c5091e3e306a542 124 Gene3D G3DSA:1.10.3340.10 25 110 1.1E-43 T 05-07-2017 IPR023163 SMc04008-like domain K08M4_RS10235 f62e12ba2180b61b3c5091e3e306a542 124 Pfam PF06844 Protein of unknown function (DUF1244) 53 119 3.1E-36 T 05-07-2017 IPR023163 SMc04008-like domain K08M4_RS10235 f62e12ba2180b61b3c5091e3e306a542 124 SUPERFAMILY SSF158757 26 103 1.96E-36 T 05-07-2017 IPR023163 SMc04008-like domain K08M4_RS03100 91a00774670b181c41a815add7ac9e3d 110 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 1.4E-44 T 05-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 K08M4_RS03100 91a00774670b181c41a815add7ac9e3d 110 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 1.4E-44 T 05-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 K08M4_RS03100 91a00774670b181c41a815add7ac9e3d 110 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 1.4E-44 T 05-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 K08M4_RS03100 91a00774670b181c41a815add7ac9e3d 110 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 1.4E-44 T 05-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 K08M4_RS03100 91a00774670b181c41a815add7ac9e3d 110 Pfam PF03840 Preprotein translocase SecG subunit 4 72 3.2E-21 T 05-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 K08M4_RS03100 91a00774670b181c41a815add7ac9e3d 110 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 73 3.7E-25 T 05-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 K08M4_RS02725 d404c510632e525dbcb31a838908d7c8 216 Gene3D G3DSA:1.10.530.10 65 178 1.9E-5 T 05-07-2017 K08M4_RS02725 d404c510632e525dbcb31a838908d7c8 216 SUPERFAMILY SSF53955 29 174 3.62E-21 T 05-07-2017 IPR023346 Lysozyme-like domain K08M4_RS13400 c07628c094d37913e90028f6d8907153 96 SUPERFAMILY SSF47598 5 81 1.05E-16 T 05-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 K08M4_RS13400 c07628c094d37913e90028f6d8907153 96 Pfam PF08681 Protein of unknown function (DUF1778) 8 80 1.9E-17 T 05-07-2017 IPR014795 Vibrio phage ICP1, Orf50 K08M4_RS13400 c07628c094d37913e90028f6d8907153 96 Gene3D G3DSA:1.20.5.780 4 81 1.4E-20 T 05-07-2017 K08M4_RS09120 187e18e7c601a0ea37ce2ee69f216105 303 Pfam PF13084 Domain of unknown function (DUF3943) 140 249 2.1E-36 T 05-07-2017 IPR025079 Domain of unknown function DUF3943 K08M4_RS00265 01ba540cc741225d216c4bbff35be9c9 103 Pfam PF12305 Protein of unknown function (DUF3630) 7 99 8.5E-38 T 05-07-2017 IPR022080 Protein of unknown function DUF3630 K08M4_RS00605 2c8b91b089d37ae35d7aaca4749dfd2b 120 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 71 82 - T 05-07-2017 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 K08M4_RS00605 2c8b91b089d37ae35d7aaca4749dfd2b 120 Pfam PF01219 Prokaryotic diacylglycerol kinase 18 118 4.7E-36 T 05-07-2017 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 K08M4_RS00605 2c8b91b089d37ae35d7aaca4749dfd2b 120 Gene3D G3DSA:1.10.3830.10 4 119 4.2E-44 T 05-07-2017 K08M4_RS20315 7afb1dc394dfb4861d98ca4bc782bca3 134 SUPERFAMILY SSF117856 3 130 9.68E-35 T 05-07-2017 K08M4_RS20315 7afb1dc394dfb4861d98ca4bc782bca3 134 Gene3D G3DSA:3.30.1330.80 3 132 3.0E-43 T 05-07-2017 K08M4_RS20315 7afb1dc394dfb4861d98ca4bc782bca3 134 Pfam PF03479 Domain of unknown function (DUF296) 3 108 3.0E-22 T 05-07-2017 IPR005175 PPC domain K08M4_RS03905 de9d894126ea01d2bafa76a11a729bb5 154 Gene3D G3DSA:3.10.129.10 2 139 2.1E-21 T 05-07-2017 IPR029069 HotDog domain K08M4_RS03905 de9d894126ea01d2bafa76a11a729bb5 154 SUPERFAMILY SSF54637 7 142 2.49E-27 T 05-07-2017 IPR029069 HotDog domain K08M4_RS03905 de9d894126ea01d2bafa76a11a729bb5 154 PIRSF PIRSF020565 1 154 7.2E-60 T 05-07-2017 IPR016776 3-hydroxylacyl-(acyl carrier protein) dehydratase, predicted K08M4_RS08685 176933bf2eaec89e07bf3e5715521654 1269 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 626 732 1.7E-16 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS08685 176933bf2eaec89e07bf3e5715521654 1269 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 507 613 8.5E-17 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS08685 176933bf2eaec89e07bf3e5715521654 1269 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 745 839 4.0E-16 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS08685 176933bf2eaec89e07bf3e5715521654 1269 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 270 375 9.1E-17 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS08685 176933bf2eaec89e07bf3e5715521654 1269 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 388 494 1.6E-16 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS08685 176933bf2eaec89e07bf3e5715521654 1269 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 170 257 2.4E-16 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS13105 d7818c2662a4e8f0ea00f97c3d2b7e9d 295 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 1 280 6.7E-87 T 05-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 K08M4_RS13105 d7818c2662a4e8f0ea00f97c3d2b7e9d 295 PIRSF PIRSF038471 2 283 5.6E-79 T 05-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 K08M4_RS13105 d7818c2662a4e8f0ea00f97c3d2b7e9d 295 Pfam PF04085 rod shape-determining protein MreC 123 269 7.1E-39 T 05-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 K08M4_RS07570 4ddb93155c323a047eef196417d222d6 281 Pfam PF00990 Diguanylate cyclase, GGDEF domain 131 260 2.7E-16 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS07570 4ddb93155c323a047eef196417d222d6 281 Gene3D G3DSA:3.30.70.270 131 260 4.3E-19 T 05-07-2017 K08M4_RS07570 4ddb93155c323a047eef196417d222d6 281 SUPERFAMILY SSF55073 134 260 1.1E-20 T 05-07-2017 IPR029787 Nucleotide cyclase K08M4_RS07570 4ddb93155c323a047eef196417d222d6 281 SMART SM00267 118 269 7.1E-10 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS07570 4ddb93155c323a047eef196417d222d6 281 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 128 260 1.4E-15 T 05-07-2017 IPR000160 GGDEF domain K08M4_RS04500 f7ef9f79800883a311e35dd52c39fcf6 207 Pfam PF03458 UPF0126 domain 5 78 1.4E-19 T 05-07-2017 IPR005115 Uncharacterised domain UPF0126 K08M4_RS04500 f7ef9f79800883a311e35dd52c39fcf6 207 Pfam PF03458 UPF0126 domain 92 163 2.4E-20 T 05-07-2017 IPR005115 Uncharacterised domain UPF0126 K08M4_RS03635 333f4708c85df3cb9eee6410fef33a6e 218 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 9 166 23.958 T 05-07-2017 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 K08M4_RS03635 333f4708c85df3cb9eee6410fef33a6e 218 Gene3D G3DSA:3.30.160.150 24 169 2.3E-55 T 05-07-2017 K08M4_RS03635 333f4708c85df3cb9eee6410fef33a6e 218 Pfam PF04390 Lipopolysaccharide-assembly 16 161 1.6E-18 T 05-07-2017 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 K08M4_RS16490 bf6808577f132df5283b3816920f54d1 418 Pfam PF03611 PTS system sugar-specific permease component 11 405 6.8E-135 T 05-07-2017 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 K08M4_RS07645 13bfed9d8f1adb26a39eae830c98da5a 159 Pfam PF05751 FixH 7 147 3.2E-43 T 05-07-2017 IPR008620 Nitrogen fixation protein FixH K08M4_RS07405 f62acd79b8489d22e17320f17c30011f 456 Pfam PF01554 MatE 17 176 1.0E-32 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS07405 f62acd79b8489d22e17320f17c30011f 456 Pfam PF01554 MatE 243 404 1.5E-35 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS07405 f62acd79b8489d22e17320f17c30011f 456 PIRSF PIRSF006603 5 453 3.6E-59 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS07405 f62acd79b8489d22e17320f17c30011f 456 TIGRFAM TIGR00797 matE: MATE efflux family protein 17 421 8.1E-115 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS18725 7678281ec06621e49333b764cd63ca8f 390 Gene3D G3DSA:3.40.1090.10 73 265 3.4E-17 T 05-07-2017 K08M4_RS18725 7678281ec06621e49333b764cd63ca8f 390 SUPERFAMILY SSF52151 78 373 2.88E-34 T 05-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 K08M4_RS18725 7678281ec06621e49333b764cd63ca8f 390 Pfam PF01734 Patatin-like phospholipase 81 265 2.6E-17 T 05-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 K08M4_RS18520 a688e3562f04001b21ab32464b497762 292 Pfam PF11060 Protein of unknown function (DUF2861) 23 287 1.3E-95 T 05-07-2017 IPR021290 Protein of unknown function DUF2861 K08M4_RS00415 cfbc199e96cc1a2037e3d67cff88384e 70 Pfam PF13627 Prokaryotic lipoprotein-attachment site 38 60 9.8E-9 T 05-07-2017 IPR032831 Prokaryotic lipoprotein-attachment site K08M4_RS05590 7e6dcb8ab12b10b502bb5bc1e7f71217 353 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 31 341 5.6E-113 T 05-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 K08M4_RS05590 7e6dcb8ab12b10b502bb5bc1e7f71217 353 SUPERFAMILY SSF142754 30 341 1.44E-105 T 05-07-2017 K08M4_RS05590 7e6dcb8ab12b10b502bb5bc1e7f71217 353 Pfam PF02445 Quinolinate synthetase A protein 32 340 1.4E-100 T 05-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 K08M4_RS09025 46bd245309dd3d8b942559909844a9bc 353 Pfam PF09375 Imelysin 58 331 1.6E-33 T 05-07-2017 K08M4_RS07425 21b9094a6a834a16ea0faf0297745c38 114 Pfam PF12290 Protein of unknown function (DUF3802) 2 110 1.3E-44 T 05-07-2017 IPR020979 Uncharacterised protein family A0KLC6 K08M4_RS18380 31582f227857332221745e0c5d70628d 410 Pfam PF13692 Glycosyl transferases group 1 197 336 3.3E-20 T 05-07-2017 K08M4_RS18380 31582f227857332221745e0c5d70628d 410 SUPERFAMILY SSF53756 7 366 2.95E-21 T 05-07-2017 K08M4_RS20615 3865b35269e363d0e285bc96fe9df965 439 Pfam PF14279 HNH endonuclease 165 214 4.0E-7 T 05-07-2017 IPR029471 HNH endonuclease 5 K08M4_RS06075 6481df7c1f0e25b708e3f53749690e98 379 Pfam PF13391 HNH endonuclease 281 330 3.7E-11 T 05-07-2017 IPR003615 HNH nuclease K08M4_RS09970 a2514bbcb743dd2bd08d4fa283c08522 162 SUPERFAMILY SSF55718 87 157 7.3E-5 T 05-07-2017 IPR003033 SCP2 sterol-binding domain K08M4_RS00540 5e462127bc6fdc22f3b01d1c4f93f233 194 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 6 189 2.4E-29 T 05-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 K08M4_RS00540 5e462127bc6fdc22f3b01d1c4f93f233 194 Pfam PF01914 MarC family integral membrane protein 3 192 3.1E-54 T 05-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 K08M4_RS05925 037d66cdca9e8abab2303b1d39fb2bd6 218 Pfam PF10014 2OG-Fe dioxygenase 24 208 4.0E-54 T 05-07-2017 IPR018724 2OG-Fe dioxygenase K08M4_RS21165 894baa1ebdf3a7227ad1e2212435e7be 296 Pfam PF00892 EamA-like transporter family 3 128 5.4E-13 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS21165 894baa1ebdf3a7227ad1e2212435e7be 296 Pfam PF00892 EamA-like transporter family 141 271 3.3E-7 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS21165 894baa1ebdf3a7227ad1e2212435e7be 296 SUPERFAMILY SSF103481 201 268 6.02E-6 T 05-07-2017 K08M4_RS17225 03cfbcb78531ce434ccc2e8ab8d28aa9 1005 PIRSF PIRSF036597 3 1005 0.0 T 05-07-2017 IPR012045 Peptidase M6, unassigned InhA-related K08M4_RS17225 03cfbcb78531ce434ccc2e8ab8d28aa9 1005 ProSitePatterns PS00018 EF-hand calcium-binding domain. 251 263 - T 05-07-2017 IPR018247 EF-Hand 1, calcium-binding site K08M4_RS17225 03cfbcb78531ce434ccc2e8ab8d28aa9 1005 SUPERFAMILY SSF55486 303 374 5.62E-7 T 05-07-2017 K08M4_RS17225 03cfbcb78531ce434ccc2e8ab8d28aa9 1005 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 152 439 2.9E-72 T 05-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 K08M4_RS17225 03cfbcb78531ce434ccc2e8ab8d28aa9 1005 Pfam PF05547 Immune inhibitor A peptidase M6 170 380 2.4E-11 T 05-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 K08M4_RS17225 03cfbcb78531ce434ccc2e8ab8d28aa9 1005 Gene3D G3DSA:3.40.390.10 286 370 1.6E-10 T 05-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 K08M4_RS08960 320a73a9f2f8ac09556c7b6540a8abd6 532 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 74 520 1.4E-133 T 05-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 K08M4_RS08960 320a73a9f2f8ac09556c7b6540a8abd6 532 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 33 520 4.2E-171 T 05-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 K08M4_RS08960 320a73a9f2f8ac09556c7b6540a8abd6 532 ProSitePatterns PS01303 BCCT family of transporters signature. 336 345 - T 05-07-2017 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 K08M4_RS15060 9bf566da53c6e35c4f5b6e5a64d4cdc4 275 Gene3D G3DSA:3.40.630.30 123 264 1.3E-11 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS15060 9bf566da53c6e35c4f5b6e5a64d4cdc4 275 SUPERFAMILY SSF55729 4 259 2.41E-18 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS15060 9bf566da53c6e35c4f5b6e5a64d4cdc4 275 Pfam PF13302 Acetyltransferase (GNAT) domain 163 259 1.9E-6 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS07335 67b12b9ea9436d8643414388ae25678f 372 Pfam PF13692 Glycosyl transferases group 1 215 319 4.4E-9 T 05-07-2017 K08M4_RS07335 67b12b9ea9436d8643414388ae25678f 372 SUPERFAMILY SSF53756 74 342 3.27E-19 T 05-07-2017 K08M4_RS07335 67b12b9ea9436d8643414388ae25678f 372 SUPERFAMILY SSF53756 11 43 3.27E-19 T 05-07-2017 K08M4_RS17485 f2bf0fd43ab6bb199344b5d5f4099073 204 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 128 166 0.0034 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS17485 f2bf0fd43ab6bb199344b5d5f4099073 204 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 5 115 8.8E-26 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS19880 042045f683ed2abc251740b3530fc96f 154 Gene3D G3DSA:2.60.120.10 30 130 2.7E-19 T 05-07-2017 IPR014710 RmlC-like jelly roll fold K08M4_RS19880 042045f683ed2abc251740b3530fc96f 154 Pfam PF07883 Cupin domain 47 118 6.0E-16 T 05-07-2017 IPR013096 Cupin 2, conserved barrel K08M4_RS19880 042045f683ed2abc251740b3530fc96f 154 SUPERFAMILY SSF51182 22 133 3.82E-20 T 05-07-2017 IPR011051 RmlC-like cupin domain K08M4_RS18610 fe7dd1b7d1516a35d139afed51bcb692 484 Gene3D G3DSA:3.50.50.60 185 281 4.1E-16 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS18610 fe7dd1b7d1516a35d139afed51bcb692 484 Gene3D G3DSA:3.50.50.60 9 146 4.1E-16 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS18610 fe7dd1b7d1516a35d139afed51bcb692 484 SUPERFAMILY SSF51905 13 258 6.4E-18 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS18610 fe7dd1b7d1516a35d139afed51bcb692 484 Pfam PF01266 FAD dependent oxidoreductase 13 334 9.3E-12 T 05-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 K08M4_RS03310 df02820143214e5213d22ca01d406bb5 163 Pfam PF07811 TadE-like protein 22 64 2.3E-11 T 05-07-2017 IPR012495 TadE-like K08M4_RS01600 235af9ef953ea4fae1476121341aa871 164 Pfam PF11075 Protein of unknown function VcgC/VcgE (DUF2780) 11 159 8.3E-23 T 05-07-2017 IPR021302 Protein of unknown function DUF2780, VcgC/VcgE K08M4_RS20080 b10084f40faccbaf5984f9f355ae32f8 206 Pfam PF07022 Bacteriophage CI repressor helix-turn-helix domain 18 81 5.8E-17 T 05-07-2017 IPR010744 Bacteriophage CI repressor GO:0003677|GO:0045892 K08M4_RS20080 b10084f40faccbaf5984f9f355ae32f8 206 Pfam PF16452 Bacteriophage CI repressor C-terminal domain 101 200 1.4E-20 T 05-07-2017 IPR032499 Bacteriophage CI repressor, C-terminal GO:0051259 K08M4_RS17660 1f15d5f0f0e1307817bf1185b6f876b5 194 Pfam PF13590 Domain of unknown function (DUF4136) 50 192 3.7E-10 T 05-07-2017 IPR025411 Domain of unknown function DUF4136 K08M4_RS14490 a51effef709b0614f02018fffbb6753e 498 Gene3D G3DSA:1.10.443.10 240 437 1.9E-9 T 05-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS14490 a51effef709b0614f02018fffbb6753e 498 SUPERFAMILY SSF56349 238 386 4.41E-9 T 05-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 K08M4_RS14490 a51effef709b0614f02018fffbb6753e 498 Pfam PF00589 Phage integrase family 244 385 6.5E-6 T 05-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 K08M4_RS19955 6845228cac780f7a4c932f5cddba76d0 194 Pfam PF11351 Holin of 3TMs, for gene-transfer release 52 168 2.4E-13 T 05-07-2017 IPR021497 Holin of 3TMs, for gene-transfer release K08M4_RS16310 5c0d52990f3d056846503698c9386b34 199 Gene3D G3DSA:3.80.10.10 28 190 4.4E-4 T 05-07-2017 IPR032675 Leucine-rich repeat domain, L domain-like K08M4_RS21270 3aa84ea33139ede2a6768771085724e1 448 ProDom PD008788 PORIN MEMBRANE PRECURSOR SIGNAL MALTOPORIN OUTER ION TRANSMEMBRANE RECEPTOR LAMB 97 424 6.0E-41 T 05-07-2017 IPR003192 Porin, LamB type GO:0006810|GO:0016020 K08M4_RS21270 3aa84ea33139ede2a6768771085724e1 448 Gene3D G3DSA:2.40.170.10 68 448 5.1E-82 T 05-07-2017 IPR003192 Porin, LamB type GO:0006810|GO:0016020 K08M4_RS21270 3aa84ea33139ede2a6768771085724e1 448 Pfam PF02264 LamB porin 69 448 3.7E-77 T 05-07-2017 IPR003192 Porin, LamB type GO:0006810|GO:0016020 K08M4_RS21270 3aa84ea33139ede2a6768771085724e1 448 SUPERFAMILY SSF56935 68 448 3.54E-88 T 05-07-2017 K08M4_RS20325 110960666d39f7cb5a62eae059bb55bc 278 PIRSF PIRSF028200 3 278 1.0E-69 T 05-07-2017 IPR016875 Uncharacterised conserved protein UCP028200 K08M4_RS18480 4be5bf660a4134a6ff83524a7983752c 336 Pfam PF11557 Solitary outer membrane autotransporter beta-barrel domain 16 335 9.5E-110 T 05-07-2017 IPR021621 Solitary outer membrane autotransporter beta-barrel domain K08M4_RS08710 974f56a73675575dee67c249667ec44e 836 Pfam PF02687 FtsX-like permease family 263 387 6.0E-12 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 K08M4_RS08710 974f56a73675575dee67c249667ec44e 836 Pfam PF02687 FtsX-like permease family 711 828 1.2E-13 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 K08M4_RS21745 264f49a45ea224b03515ea2bb1b3c5bb 162 SUPERFAMILY SSF55729 31 141 7.27E-17 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS21745 264f49a45ea224b03515ea2bb1b3c5bb 162 Pfam PF13302 Acetyltransferase (GNAT) domain 42 135 2.0E-11 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS21745 264f49a45ea224b03515ea2bb1b3c5bb 162 Gene3D G3DSA:3.40.630.30 42 146 4.3E-18 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS16600 3547f9f01bbc6a5f47876d7c9a993b62 421 Pfam PF13520 Amino acid permease 11 394 1.7E-27 T 05-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 K08M4_RS16600 3547f9f01bbc6a5f47876d7c9a993b62 421 PIRSF PIRSF006060 1 418 2.6E-52 T 05-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 K08M4_RS19395 9c15f99d4b3719c29b358387e19fa99f 132 SUPERFAMILY SSF55298 13 127 2.04E-29 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS19395 9c15f99d4b3719c29b358387e19fa99f 132 Gene3D G3DSA:3.30.1330.40 12 128 8.4E-30 T 05-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like K08M4_RS19395 9c15f99d4b3719c29b358387e19fa99f 132 Pfam PF01042 Endoribonuclease L-PSP 18 126 4.8E-23 T 05-07-2017 IPR006175 YjgF/YER057c/UK114 family K08M4_RS05965 c1340d3da8968d9a3b285006c5bb043c 278 Gene3D G3DSA:3.40.50.620 59 184 3.0E-7 T 05-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold K08M4_RS05965 c1340d3da8968d9a3b285006c5bb043c 278 Pfam PF02698 DUF218 domain 64 201 5.9E-19 T 05-07-2017 IPR003848 Domain of unknown function DUF218 K08M4_RS17425 b6c5da13d882399d95346327da780d4d 370 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 336 5.6E-69 T 05-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 K08M4_RS17425 b6c5da13d882399d95346327da780d4d 370 SUPERFAMILY SSF51395 2 352 7.63E-101 T 05-07-2017 K08M4_RS17425 b6c5da13d882399d95346327da780d4d 370 Gene3D G3DSA:3.20.20.70 2 352 2.0E-110 T 05-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 K08M4_RS00510 16aa53093583a36c3cb52b394cd3d8a8 337 Pfam PF01757 Acyltransferase family 7 326 3.8E-29 T 05-07-2017 IPR002656 Acyltransferase 3 GO:0016747 K08M4_RS02255 7579f98e9b71732cdad712f18a4e9653 219 SUPERFAMILY SSF63965 14 215 3.4E-67 T 05-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 K08M4_RS02255 7579f98e9b71732cdad712f18a4e9653 219 Gene3D G3DSA:3.40.50.10230 4 214 1.0E-77 T 05-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 K08M4_RS02255 7579f98e9b71732cdad712f18a4e9653 219 Pfam PF02570 Precorrin-8X methylmutase 14 215 5.2E-74 T 05-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 K08M4_RS02135 d9beb765d15ef40c78c5c74abe2947c5 143 Pfam PF14467 Domain of unknown function (DUF4426) 23 142 2.5E-47 T 05-07-2017 IPR025218 Domain of unknown function DUF4426 K08M4_RS21450 2084eb35ad40f51082885745d926afd1 155 Pfam PF07670 Nucleoside recognition 31 124 6.8E-7 T 05-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 K08M4_RS08495 5c729a1b58159f5bd5f689e091ade3d3 417 Pfam PF03222 Tryptophan/tyrosine permease family 29 382 6.9E-18 T 05-07-2017 IPR018227 Tryptophan/tyrosine permease GO:0003333 K08M4_RS04955 1c1c829a8a5bba506c251cf915373bf4 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 1.6E-40 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS04955 1c1c829a8a5bba506c251cf915373bf4 306 Gene3D G3DSA:1.10.3720.10 88 300 4.3E-19 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS04955 1c1c829a8a5bba506c251cf915373bf4 306 SUPERFAMILY SSF161098 88 291 6.02E-21 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS04490 1e01a00224f1dd934b078d1ff1785b43 200 SUPERFAMILY SSF52096 89 199 1.89E-5 T 05-07-2017 IPR029045 ClpP/crotonase-like domain K08M4_RS01115 c18d66fc0719e775760cd2e5645ead32 80 Hamap MF_01196 Cell division protein ZapB [zapB]. 1 79 17.976 T 05-07-2017 IPR009252 Cell division protein ZapB GO:0000917|GO:0005737|GO:0043093 K08M4_RS01115 c18d66fc0719e775760cd2e5645ead32 80 Pfam PF06005 Protein of unknown function (DUF904) 1 77 1.2E-26 T 05-07-2017 IPR009252 Cell division protein ZapB GO:0000917|GO:0005737|GO:0043093 K08M4_RS04005 7b0567b8b88a34450806d0034966aaee 211 PIRSF PIRSF028688 1 211 6.4E-116 T 05-07-2017 IPR014549 Flagellar protein FlgO K08M4_RS13865 88a2fd4dd51fa01b14b65a05d871a12a 660 SUPERFAMILY SSF56784 1 214 9.23E-10 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS13865 88a2fd4dd51fa01b14b65a05d871a12a 660 Gene3D G3DSA:3.40.50.1000 127 218 1.1E-11 T 05-07-2017 IPR023214 HAD-like domain K08M4_RS06025 bf0910eab33c1c32b13a0b574b254a43 153 Pfam PF04191 Phospholipid methyltransferase 41 142 4.3E-12 T 05-07-2017 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 K08M4_RS06025 bf0910eab33c1c32b13a0b574b254a43 153 ProDom PD049902 METHYLTRANSFERASE TRANSFERASE PRECURSOR ISOPRENYLCYSTEINE SIGNAL CARBOXYL TRANSMEMBRANE MEMBRANE FAMILY XCC3183 112 153 9.0E-11 T 05-07-2017 K08M4_RS05860 f45786998e9add14e0c0611b0a6b772b 91 Pfam PF03206 Nitrogen fixation protein NifW 7 73 5.9E-6 T 05-07-2017 IPR004893 Nitrogen fixation protein NifW GO:0009399 K08M4_RS07085 30498ca1e1d95c751aa268713da2795e 185 Pfam PF06042 Nucleotidyltransferase 23 181 1.3E-35 T 05-07-2017 IPR009267 Putative nucleotidyltransferase K08M4_RS06860 a41224163bbed5b7f67b615d79abbf49 446 Pfam PF10117 McrBC 5-methylcytosine restriction system component 66 396 7.5E-91 T 05-07-2017 IPR019292 5-methylcytosine restriction system component K08M4_RS16740 c949a0e2aaba39b8f90c7f1a8e92edf3 76 Pfam PF11137 Protein of unknown function (DUF2909) 10 69 4.0E-15 T 05-07-2017 IPR021313 Protein of unknown function DUF2909 K08M4_RS14595 7f4a95cae2294cd857bf9f85614575db 312 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 18 69 2.9E-10 T 05-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain K08M4_RS14595 7f4a95cae2294cd857bf9f85614575db 312 SUPERFAMILY SSF161098 93 295 2.09E-24 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS14595 7f4a95cae2294cd857bf9f85614575db 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 309 2.7E-29 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS14595 7f4a95cae2294cd857bf9f85614575db 312 Gene3D G3DSA:1.10.3720.10 92 307 7.3E-27 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS15610 cb2447d6708ae25841b845828b4a07b3 80 Pfam PF06224 Winged helix DNA-binding domain 37 72 1.2E-6 T 05-07-2017 IPR009351 Protein of unknown function DUF1006 K08M4_RS21075 a36b6affd4aafb776369065969ecd04d 480 SUPERFAMILY SSF48208 24 445 4.93E-49 T 05-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 K08M4_RS21075 a36b6affd4aafb776369065969ecd04d 480 Gene3D G3DSA:1.50.10.10 85 314 1.6E-12 T 05-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 K08M4_RS00545 ce7786932b3866dff6260c1165a1bf44 88 Pfam PF06611 Protein of unknown function (DUF1145) 4 59 1.6E-17 T 05-07-2017 IPR009525 Protein of unknown function DUF1145 K08M4_RS06395 636996562e042e261ddba3893d430f2c 231 PIRSF PIRSF028137 1 231 7.0E-99 T 05-07-2017 IPR016870 Uncharacterised conserved protein UCP028137, membrane K08M4_RS03165 26a51747c1488d5826d358e4e789c2e5 296 Pfam PF01136 Peptidase family U32 85 244 4.3E-15 T 05-07-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 K08M4_RS05790 a6407c225462a12da5bb126bb5bbf56f 131 Gene3D G3DSA:3.40.190.10 20 128 3.0E-5 T 05-07-2017 K08M4_RS05790 a6407c225462a12da5bb126bb5bbf56f 131 SUPERFAMILY SSF53850 11 128 3.8E-10 T 05-07-2017 K08M4_RS13960 9a62c84402efc66df5c93c7a0801eb62 354 Gene3D G3DSA:3.40.50.2000 11 153 4.4E-24 T 05-07-2017 K08M4_RS13960 9a62c84402efc66df5c93c7a0801eb62 354 SUPERFAMILY SSF53756 9 345 3.3E-81 T 05-07-2017 K08M4_RS13960 9a62c84402efc66df5c93c7a0801eb62 354 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 76 308 8.5E-54 T 05-07-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 K08M4_RS13960 9a62c84402efc66df5c93c7a0801eb62 354 Gene3D G3DSA:3.40.50.2000 171 344 4.1E-43 T 05-07-2017 K08M4_RS21540 5158d9e158f453a04875f24bbc8b0329 392 Pfam PF04932 O-Antigen ligase 178 332 1.6E-17 T 05-07-2017 IPR007016 O-antigen ligase-related K08M4_RS17750 93fa721783574973c6708a99d01d60de 206 PIRSF PIRSF006324 1 206 3.0E-46 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS17750 93fa721783574973c6708a99d01d60de 206 Pfam PF01810 LysE type translocator 15 204 7.2E-26 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS19745 0452a39e5262f4e709425aff04425da2 142 Pfam PF05232 Chlorhexidine efflux transporter 1 62 6.2E-18 T 05-07-2017 IPR007896 Chlorhexidine efflux transporter K08M4_RS19745 0452a39e5262f4e709425aff04425da2 142 Pfam PF05232 Chlorhexidine efflux transporter 69 131 1.1E-23 T 05-07-2017 IPR007896 Chlorhexidine efflux transporter K08M4_RS03345 bacb7ab0e03cdb8f37fcda8d4ed76b3a 449 SUPERFAMILY SSF52540 152 198 6.07E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03345 bacb7ab0e03cdb8f37fcda8d4ed76b3a 449 SUPERFAMILY SSF52540 249 393 6.07E-18 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03345 bacb7ab0e03cdb8f37fcda8d4ed76b3a 449 SMART SM00382 171 362 0.0038 T 05-07-2017 IPR003593 AAA+ ATPase domain K08M4_RS03345 bacb7ab0e03cdb8f37fcda8d4ed76b3a 449 Gene3D G3DSA:3.40.50.300 150 205 4.8E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS03345 bacb7ab0e03cdb8f37fcda8d4ed76b3a 449 Gene3D G3DSA:3.40.50.300 256 373 4.8E-12 T 05-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase K08M4_RS15560 a343698a0a097b667a03131d7b32860b 153 Pfam PF02794 RTX toxin acyltransferase family 19 150 4.1E-45 T 05-07-2017 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 K08M4_RS15560 a343698a0a097b667a03131d7b32860b 153 PRINTS PR01489 Gram-negative bacterial RTX toxin-activating protein C signature 85 107 7.7E-6 T 05-07-2017 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 K08M4_RS15560 a343698a0a097b667a03131d7b32860b 153 PRINTS PR01489 Gram-negative bacterial RTX toxin-activating protein C signature 20 36 7.7E-6 T 05-07-2017 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 K08M4_RS15560 a343698a0a097b667a03131d7b32860b 153 PRINTS PR01489 Gram-negative bacterial RTX toxin-activating protein C signature 63 81 7.7E-6 T 05-07-2017 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 K08M4_RS11620 8c76ab72dd480d0c386092d7e8b655a6 213 Pfam PF01914 MarC family integral membrane protein 8 207 7.5E-52 T 05-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 K08M4_RS11620 8c76ab72dd480d0c386092d7e8b655a6 213 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 8 204 1.6E-48 T 05-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 K08M4_RS14420 a276b17f3704ac3cdd0c5e63efe6fe48 510 Pfam PF02646 RmuC family 181 478 4.9E-107 T 05-07-2017 IPR003798 DNA recombination RmuC K08M4_RS12720 72cffabb121938151d7faba66c9e7084 146 Pfam PF06853 Protein of unknown function (DUF1249) 27 139 2.1E-38 T 05-07-2017 IPR009659 Protein of unknown function DUF1249 K08M4_RS20010 9407a1e46d14a8ba8cfdf53d2dc35109 592 Pfam PF06056 Putative ATPase subunit of terminase (gpP-like) 6 63 1.2E-19 T 05-07-2017 IPR010332 ATPase terminase subunit, putative GO:0005524|GO:0019069 K08M4_RS20010 9407a1e46d14a8ba8cfdf53d2dc35109 592 Pfam PF03237 Terminase-like family 170 577 6.0E-106 T 05-07-2017 IPR004921 Terminase, large subunit K08M4_RS20155 8fe5d264ad5ec546daadcdf9fae56677 88 Pfam PF11280 Protein of unknown function (DUF3081) 5 80 9.6E-28 T 05-07-2017 IPR021432 Protein of unknown function DUF3081 K08M4_RS04290 93f1ea375ef66e9a28086154a846e656 222 Pfam PF03379 CcmB protein 5 219 5.7E-89 T 05-07-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04290 93f1ea375ef66e9a28086154a846e656 222 PIRSF PIRSF002764 1 222 9.6E-84 T 05-07-2017 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria K08M4_RS04290 93f1ea375ef66e9a28086154a846e656 222 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 8 218 2.6E-90 T 05-07-2017 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria K08M4_RS04290 93f1ea375ef66e9a28086154a846e656 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 29 50 5.3E-70 T 05-07-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04290 93f1ea375ef66e9a28086154a846e656 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 195 218 5.3E-70 T 05-07-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04290 93f1ea375ef66e9a28086154a846e656 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 103 121 5.3E-70 T 05-07-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04290 93f1ea375ef66e9a28086154a846e656 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 78 101 5.3E-70 T 05-07-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04290 93f1ea375ef66e9a28086154a846e656 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 158 177 5.3E-70 T 05-07-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS04290 93f1ea375ef66e9a28086154a846e656 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 55 72 5.3E-70 T 05-07-2017 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 K08M4_RS10730 249571aba10d74c2be98393d15fd249e 264 Pfam PF07556 Protein of unknown function (DUF1538) 21 246 4.1E-70 T 05-07-2017 IPR011435 Protein of unknown function DUF1538 K08M4_RS07865 505db5b57da8b580abea42c71062c107 301 SMART SM00316 92 155 2.9 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS07865 505db5b57da8b580abea42c71062c107 301 SMART SM00316 26 87 15.0 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS07865 505db5b57da8b580abea42c71062c107 301 SMART SM00316 168 231 0.22 T 05-07-2017 IPR022967 RNA-binding domain, S1 K08M4_RS07865 505db5b57da8b580abea42c71062c107 301 Pfam PF13509 S1 domain 27 87 9.4E-23 T 05-07-2017 K08M4_RS07865 505db5b57da8b580abea42c71062c107 301 PIRSF PIRSF012524 23 301 1.7E-95 T 05-07-2017 IPR014464 Conserved virulence factor B K08M4_RS05345 cf6539bfb2e953c02a2b804e925da4b7 220 Pfam PF09829 Uncharacterized protein conserved in bacteria (DUF2057) 22 215 5.0E-33 T 05-07-2017 IPR018635 Uncharacterised protein family UPF0319 K08M4_RS19105 7baa6549ff85320e520358d9c51a126c 789 Pfam PF11308 Glycosyl hydrolases related to GH101 family, GH129 419 743 1.1E-148 T 05-07-2017 IPR021459 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 K08M4_RS07475 958487daff08b048910ef2a405137c58 232 Gene3D G3DSA:1.10.3720.10 18 227 3.7E-26 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07475 958487daff08b048910ef2a405137c58 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 220 3.6E-12 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS07475 958487daff08b048910ef2a405137c58 232 SUPERFAMILY SSF161098 17 222 7.33E-32 T 05-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 K08M4_RS13800 3932c723e650041385af974c53bb7598 236 Pfam PF00535 Glycosyl transferase family 2 5 111 8.0E-20 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 K08M4_RS13800 3932c723e650041385af974c53bb7598 236 SUPERFAMILY SSF53448 1 232 3.09E-31 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS13800 3932c723e650041385af974c53bb7598 236 Gene3D G3DSA:3.90.550.10 2 118 2.2E-20 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS19810 7faeb75a43067f089089972cc7330a87 342 Pfam PF14321 Domain of unknown function (DUF4382) 31 201 6.9E-18 T 05-07-2017 IPR025491 Domain of unknown function DUF4382 K08M4_RS11750 f3ce37a4080104193aa6c76f62fe8ecd 275 SUPERFAMILY SSF55166 53 158 1.8E-27 T 05-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 K08M4_RS11750 f3ce37a4080104193aa6c76f62fe8ecd 275 SUPERFAMILY SSF55166 185 215 1.8E-27 T 05-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 K08M4_RS11750 f3ce37a4080104193aa6c76f62fe8ecd 275 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 125 214 2.4E-20 T 05-07-2017 K08M4_RS15420 953cd856ba473fcf706b02ae14c34410 233 SUPERFAMILY SSF55681 4 232 1.59E-44 T 05-07-2017 K08M4_RS15420 953cd856ba473fcf706b02ae14c34410 233 Gene3D G3DSA:3.90.1550.10 3 231 3.6E-49 T 05-07-2017 K08M4_RS11120 10fa6795bf512db42b03f6b7e1463e47 228 Pfam PF06930 Protein of unknown function (DUF1282) 14 223 2.7E-47 T 05-07-2017 IPR009698 Protein of unknown function DUF1282 K08M4_RS19930 39ea530e1317f278946f4bcce16f4316 397 Pfam PF04865 Baseplate J-like protein 91 336 8.0E-25 T 05-07-2017 IPR006949 Baseplate protein J-like K08M4_RS19945 be2e8b6b2f2c7566ef9a8d5d4348a505 93 Pfam PF10963 Phage tail assembly chaperone 12 93 3.4E-22 T 05-07-2017 IPR024406 Phage tail assembly chaperone TAC_10 K08M4_RS19945 be2e8b6b2f2c7566ef9a8d5d4348a505 93 ProDom PD068655 ORF26 3'REGION LYS GENE PRECURSOR ORF30 SIGNAL PHAGE 17 92 2.0E-20 T 05-07-2017 IPR024406 Phage tail assembly chaperone TAC_10 K08M4_RS21170 cb09f1cd4d26adb0e3cef082bfb5b605 304 SUPERFAMILY SSF103481 40 141 1.57E-12 T 05-07-2017 K08M4_RS21170 cb09f1cd4d26adb0e3cef082bfb5b605 304 SUPERFAMILY SSF103481 190 290 6.54E-6 T 05-07-2017 K08M4_RS21170 cb09f1cd4d26adb0e3cef082bfb5b605 304 Pfam PF00892 EamA-like transporter family 156 286 6.6E-15 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS21170 cb09f1cd4d26adb0e3cef082bfb5b605 304 Pfam PF00892 EamA-like transporter family 7 139 5.8E-24 T 05-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 K08M4_RS09910 9ab7e4b3782a11d04a7279bb39f7f199 487 PIRSF PIRSF006603 1 446 5.2E-78 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS09910 9ab7e4b3782a11d04a7279bb39f7f199 487 Pfam PF01554 MatE 243 403 1.2E-17 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS09910 9ab7e4b3782a11d04a7279bb39f7f199 487 Pfam PF01554 MatE 29 184 5.8E-24 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS09910 9ab7e4b3782a11d04a7279bb39f7f199 487 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 409 4.2E-56 T 05-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 K08M4_RS20550 f33caa81aa309fb13e1d5aa451326f4e 258 Pfam PF01755 Glycosyltransferase family 25 (LPS biosynthesis protein) 3 181 4.1E-29 T 05-07-2017 IPR002654 Glycosyl transferase, family 25 K08M4_RS19330 b67205b9ea33213bad101866a233b0ad 151 SUPERFAMILY SSF56524 21 150 5.1E-16 T 05-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 K08M4_RS20300 28075bcbe501e2971733a8dd1a44241b 488 SUPERFAMILY SSF117074 46 80 7.59E-5 T 05-07-2017 K08M4_RS06510 7d6914869c2283f8b79643fd683d693a 282 Pfam PF04116 Fatty acid hydroxylase superfamily 92 226 2.7E-31 T 05-07-2017 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 K08M4_RS19375 7b8b44c43ab2d3d81c447d777c28cdef 535 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 46 523 2.7E-142 T 05-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 K08M4_RS20295 f78c30aa1389c3ca356b20446874aa9b 543 Gene3D G3DSA:3.50.50.60 473 530 2.0E-33 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS20295 f78c30aa1389c3ca356b20446874aa9b 543 Gene3D G3DSA:3.50.50.60 100 288 2.0E-33 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS20295 f78c30aa1389c3ca356b20446874aa9b 543 SUPERFAMILY SSF51905 479 528 3.29E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS20295 f78c30aa1389c3ca356b20446874aa9b 543 SUPERFAMILY SSF51905 100 286 3.29E-34 T 05-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 K08M4_RS20295 f78c30aa1389c3ca356b20446874aa9b 543 PIRSF PIRSF038984 1 535 1.6E-237 T 05-07-2017 IPR028348 FAD dependent protein K08M4_RS07430 4ed6a9550599528a7ff923e8caf4c4ff 161 Gene3D G3DSA:3.90.1720.10 37 161 4.2E-41 T 05-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain K08M4_RS07430 4ed6a9550599528a7ff923e8caf4c4ff 161 SUPERFAMILY SSF54001 40 161 2.16E-39 T 05-07-2017 K08M4_RS07430 4ed6a9550599528a7ff923e8caf4c4ff 161 Pfam PF00877 NlpC/P60 family 56 160 2.4E-29 T 05-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain K08M4_RS03280 1da065091ab7e1e5bb369c7a6e2329c6 796 Pfam PF00577 Outer membrane usher protein 257 648 1.2E-13 T 05-07-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 K08M4_RS06970 7d4c7ad7f00a95cd2c6ac142a4ab18be 376 Pfam PF14284 PcfJ-like protein 241 360 2.4E-11 T 05-07-2017 IPR025586 PcfJ-like protein K08M4_RS15265 4f77ac42ee28ebc474da929d86c12628 181 Pfam PF04972 BON domain 33 98 8.4E-17 T 05-07-2017 IPR007055 BON domain K08M4_RS15265 4f77ac42ee28ebc474da929d86c12628 181 Pfam PF04972 BON domain 114 180 1.3E-13 T 05-07-2017 IPR007055 BON domain K08M4_RS12270 41c4ef1e8e15b4fcac4e6386748af2cf 381 Pfam PF02690 Na+/Pi-cotransporter 217 329 4.6E-19 T 05-07-2017 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 K08M4_RS12270 41c4ef1e8e15b4fcac4e6386748af2cf 381 Pfam PF02690 Na+/Pi-cotransporter 29 147 4.8E-23 T 05-07-2017 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 K08M4_RS11350 b3eea7ecf0eb9fce8a5b28f4baf2d4d0 200 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 11 187 5.4E-35 T 05-07-2017 IPR003740 Uncharacterised membrane protein YitT K08M4_RS19965 590904b07c1c257399737dc761674102 72 SUPERFAMILY SSF57716 39 69 5.63E-5 T 05-07-2017 K08M4_RS19965 590904b07c1c257399737dc761674102 72 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 37 69 4.9E-9 T 05-07-2017 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 K08M4_RS01860 918621c3940d8b1a184c5e915fc094fb 231 Gene3D G3DSA:1.10.10.640 97 131 6.2E-9 T 05-07-2017 IPR023094 Toluene tolerance protein, alpha-helical K08M4_RS01860 918621c3940d8b1a184c5e915fc094fb 231 Gene3D G3DSA:1.10.10.640 193 223 6.2E-9 T 05-07-2017 IPR023094 Toluene tolerance protein, alpha-helical K08M4_RS01860 918621c3940d8b1a184c5e915fc094fb 231 PIRSF PIRSF004649 19 231 3.8E-55 T 05-07-2017 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC K08M4_RS01860 918621c3940d8b1a184c5e915fc094fb 231 Pfam PF05494 MlaC protein 53 219 2.1E-45 T 05-07-2017 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC K08M4_RS01860 918621c3940d8b1a184c5e915fc094fb 231 Gene3D G3DSA:3.10.450.50 46 90 6.5E-18 T 05-07-2017 IPR032710 NTF2-like domain K08M4_RS01860 918621c3940d8b1a184c5e915fc094fb 231 Gene3D G3DSA:3.10.450.50 134 192 6.5E-18 T 05-07-2017 IPR032710 NTF2-like domain K08M4_RS08780 47045d6d7637e3bfd100155112c8edde 242 Pfam PF00535 Glycosyl transferase family 2 5 115 1.7E-24 T 05-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 K08M4_RS08780 47045d6d7637e3bfd100155112c8edde 242 Gene3D G3DSA:3.90.550.10 3 223 1.2E-35 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS08780 47045d6d7637e3bfd100155112c8edde 242 SUPERFAMILY SSF53448 3 224 7.03E-41 T 05-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases K08M4_RS07760 896b6c0a15a98c89a3376b2e750c889e 151 Pfam PF06303 Organiser of macrodomain of Terminus of chromosome 1 147 3.9E-71 T 05-07-2017 IPR009390 Macrodomain Ter protein, MatP GO:0043565 K08M4_RS07760 896b6c0a15a98c89a3376b2e750c889e 151 ProDom PD033720 UPF0268 YCBG DEHYDROGENASE PM0482 PBPRA1775 PLU1774 YPO1433/Y2737/YP0877 VV1664 HI1323 HD0178 1 134 4.0E-60 T 05-07-2017 IPR009390 Macrodomain Ter protein, MatP GO:0043565 K08M4_RS07760 896b6c0a15a98c89a3376b2e750c889e 151 Hamap MF_01073 Macrodomain Ter protein [matP]. 1 148 28.646 T 05-07-2017 IPR009390 Macrodomain Ter protein, MatP GO:0043565 K08M4_RS21490 ca794b494474b5caa739eea45e9aaf0e 117 Pfam PF04219 Protein of unknown function, DUF 12 100 4.2E-35 T 05-07-2017 IPR007335 Protein of unknown function DUF413 K08M4_RS07175 d97380267edfb8ef109aeec1e7857949 154 Pfam PF13279 Thioesterase-like superfamily 16 125 2.3E-21 T 05-07-2017 K08M4_RS07175 d97380267edfb8ef109aeec1e7857949 154 Gene3D G3DSA:3.10.129.10 4 134 7.6E-39 T 05-07-2017 IPR029069 HotDog domain K08M4_RS07175 d97380267edfb8ef109aeec1e7857949 154 SUPERFAMILY SSF54637 7 136 3.09E-31 T 05-07-2017 IPR029069 HotDog domain K08M4_RS17450 f5000efa4a2ba345676146bfb56798b9 267 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 50 137 2.1E-24 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS00210 c88b72f36ea01375e9916658533b2190 152 Pfam PF07681 DoxX 28 109 5.6E-19 T 05-07-2017 IPR032808 DoxX family K08M4_RS02195 c03205a8d741f66ac2d55e0accf45d27 243 SUPERFAMILY SSF54060 33 242 1.53E-93 T 05-07-2017 K08M4_RS02195 c03205a8d741f66ac2d55e0accf45d27 243 Pfam PF04231 Endonuclease I 47 240 3.3E-47 T 05-07-2017 IPR007346 Endonuclease I GO:0004518 K08M4_RS17120 d06fc17c9f78c1e917ee327360e9a3e8 205 Gene3D G3DSA:3.40.50.360 5 179 2.3E-48 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS17120 d06fc17c9f78c1e917ee327360e9a3e8 205 SUPERFAMILY SSF52218 5 179 4.59E-50 T 05-07-2017 IPR029039 Flavoprotein-like domain K08M4_RS17120 d06fc17c9f78c1e917ee327360e9a3e8 205 Pfam PF02525 Flavodoxin-like fold 5 173 9.3E-45 T 05-07-2017 IPR003680 Flavodoxin-like fold K08M4_RS04025 5fc39e1e4b3c387b1de601a24bc83b3d 248 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 114 246 2.2E-39 T 05-07-2017 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal K08M4_RS04025 5fc39e1e4b3c387b1de601a24bc83b3d 248 SMART SM00858 126 188 5.8E-7 T 05-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 K08M4_RS04025 5fc39e1e4b3c387b1de601a24bc83b3d 248 Pfam PF13144 Chaperone for flagella basal body P-ring formation 49 246 4.1E-51 T 05-07-2017 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal K08M4_RS16020 1b2dd7865dc01ae4240b03898e803ce4 312 Pfam PF01882 Protein of unknown function DUF58 52 136 1.4E-21 T 05-07-2017 IPR002881 Domain of unknown function DUF58 K08M4_RS17050 0f5361ae159f6011ef121587f5c60ccc 511 Pfam PF03929 PepSY-associated TM region 44 448 9.1E-53 T 05-07-2017 IPR005625 PepSY-associated TM protein K08M4_RS04165 4708e997a740d170031a401b3e99ff71 266 PRINTS PR01003 Flagellar assembly protein FliH signature 217 233 1.1E-5 T 05-07-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 K08M4_RS04165 4708e997a740d170031a401b3e99ff71 266 PRINTS PR01003 Flagellar assembly protein FliH signature 147 164 1.1E-5 T 05-07-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 K08M4_RS04165 4708e997a740d170031a401b3e99ff71 266 PRINTS PR01003 Flagellar assembly protein FliH signature 85 107 1.1E-5 T 05-07-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 K08M4_RS04165 4708e997a740d170031a401b3e99ff71 266 Pfam PF02108 Flagellar assembly protein FliH 125 252 7.0E-35 T 05-07-2017 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE K08M4_RS18700 d0cc10732f78ee232bf976a349c40e4d 811 TIGRFAM TIGR03502 lipase_Pla1_cef: extracellular lipase, Pla-1/cef family 1 795 2.8E-217 T 05-07-2017 IPR020009 Extracellular lipase, Pla-1/cef family K08M4_RS18700 d0cc10732f78ee232bf976a349c40e4d 811 SUPERFAMILY SSF53474 545 600 3.27E-14 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS18700 d0cc10732f78ee232bf976a349c40e4d 811 SUPERFAMILY SSF53474 445 503 3.27E-14 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS18700 d0cc10732f78ee232bf976a349c40e4d 811 Gene3D G3DSA:3.40.50.1820 440 629 3.6E-24 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS18700 d0cc10732f78ee232bf976a349c40e4d 811 Gene3D G3DSA:3.40.50.1820 685 719 3.6E-24 T 05-07-2017 IPR029058 Alpha/Beta hydrolase fold K08M4_RS18700 d0cc10732f78ee232bf976a349c40e4d 811 Pfam PF12262 Bacterial virulence factor lipase N-terminal 1 275 3.7E-120 T 05-07-2017 IPR025920 Bacterial virulence factor lipase, N-terminal domain K08M4_RS05825 c8bb06ad620fcd44f40a58a3b88654e4 86 Pfam PF06945 Protein of unknown function (DUF1289) 11 56 1.8E-18 T 05-07-2017 IPR010710 Protein of unknown function DUF1289 K08M4_RS15850 4365858c387da9082bc6a0f1501a30e5 152 SUPERFAMILY SSF110087 3 141 9.94E-50 T 05-07-2017 IPR007410 DR1885-like metal-binding protein K08M4_RS15850 4365858c387da9082bc6a0f1501a30e5 152 Pfam PF04314 Protein of unknown function (DUF461) 25 132 4.1E-39 T 05-07-2017 IPR007410 DR1885-like metal-binding protein K08M4_RS20035 bb6c92a2c54a6fce945dbb5c847c51cb 883 Pfam PF05840 Bacteriophage replication gene A protein (GPA) 212 599 2.8E-137 T 05-07-2017 IPR008766 Replication gene A protein GO:0006260 K08M4_RS17240 f9319f0b9b7236152baeb48c3acaf5f2 68 Pfam PF04964 Flp/Fap pilin component 17 59 1.6E-10 T 05-07-2017 IPR007047 Flp/Fap pilin component K08M4_RS06010 a2517c9f1a9e6657ffda7e8ba7ad8091 229 PIRSF PIRSF028111 1 229 4.1E-83 T 05-07-2017 IPR016868 Bacteriophage B3, Orf5 K08M4_RS06010 a2517c9f1a9e6657ffda7e8ba7ad8091 229 Pfam PF10979 Protein of unknown function (DUF2786) 5 42 2.6E-10 T 05-07-2017 IPR024498 Domain of unknown function DUF2786 K08M4_RS12210 db456148cc593fea3ea0ee9ddf0af260 499 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 328 437 2.7E-21 T 05-07-2017 IPR025299 CstA, C-terminal domain K08M4_RS12210 db456148cc593fea3ea0ee9ddf0af260 499 Pfam PF02554 Carbon starvation protein CstA 4 144 3.8E-33 T 05-07-2017 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 K08M4_RS10995 fb6fcb012b8a25b23f15a76faaa19ca2 69 Pfam PF11446 Protein of unknown function (DUF2897) 4 55 6.9E-20 T 05-07-2017 IPR021550 Protein of unknown function DUF2897 K08M4_RS07855 cf894e7a2fedb610f849ec1bd8705113 885 Pfam PF02470 MlaD protein 283 373 2.5E-7 T 05-07-2017 IPR003399 Mce/MlaD K08M4_RS07855 cf894e7a2fedb610f849ec1bd8705113 885 Pfam PF02470 MlaD protein 165 223 1.8E-6 T 05-07-2017 IPR003399 Mce/MlaD K08M4_RS07855 cf894e7a2fedb610f849ec1bd8705113 885 Pfam PF02470 MlaD protein 47 137 3.0E-13 T 05-07-2017 IPR003399 Mce/MlaD K08M4_RS21455 5bb2bfefc021d736c6f095fc8e0c954d 245 Pfam PF07670 Nucleoside recognition 85 179 1.1E-10 T 05-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 K08M4_RS10735 384fbd2d757f317394cf588b9fa9861a 240 Pfam PF07556 Protein of unknown function (DUF1538) 21 239 2.6E-71 T 05-07-2017 IPR011435 Protein of unknown function DUF1538 K08M4_RS05545 3cd22e08fd674eb53e4dbf06352a574e 35 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 30 1.1E-20 T 05-07-2017 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 K08M4_RS05545 3cd22e08fd674eb53e4dbf06352a574e 35 Pfam PF08173 Membrane bound YbgT-like protein 1 27 1.2E-17 T 05-07-2017 IPR012994 Membrane bound YbgT-like K08M4_RS10950 dd81dde98f944f1f4102697465629f08 52 Pfam PF09904 Winged helix-turn helix 13 47 4.2E-11 T 05-07-2017 IPR017162 Uncharacterised conserved protein UCP037266 K08M4_RS00745 f5a19117d3a157dbc2ecd8eda3bf7972 52 Pfam PF13592 Winged helix-turn helix 1 46 1.8E-11 T 05-07-2017 IPR025959 Winged helix-turn helix domain K08M4_RS13405 a2c973f9148e3cde3369eb48ad75abae 182 Pfam PF00583 Acetyltransferase (GNAT) family 64 154 2.1E-5 T 05-07-2017 IPR000182 GNAT domain GO:0008080 K08M4_RS13405 a2c973f9148e3cde3369eb48ad75abae 182 SUPERFAMILY SSF55729 65 165 2.66E-11 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS13405 a2c973f9148e3cde3369eb48ad75abae 182 Gene3D G3DSA:3.40.630.30 9 162 2.2E-10 T 05-07-2017 IPR016181 Acyl-CoA N-acyltransferase K08M4_RS08520 571988d12dd4bc3a387ff656aeafd041 496 SUPERFAMILY SSF52091 399 480 5.3E-7 T 05-07-2017 IPR002645 STAS domain K08M4_RS08520 571988d12dd4bc3a387ff656aeafd041 496 Gene3D G3DSA:3.30.750.24 399 470 7.3E-4 T 05-07-2017 IPR002645 STAS domain K08M4_RS08520 571988d12dd4bc3a387ff656aeafd041 496 Pfam PF00916 Sulfate permease family 147 344 3.4E-30 T 05-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 K08M4_RS08520 571988d12dd4bc3a387ff656aeafd041 496 Pfam PF00916 Sulfate permease family 14 143 2.2E-28 T 05-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 K08M4_RS01030 0c444cd6a0b0e97db0692a36a6b3b316 481 Pfam PF03606 C4-dicarboxylate anaerobic carrier 20 477 1.1E-137 T 05-07-2017 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 K08M4_RS08265 79b4ae04aaed21aa4a6c91814e63dafc 299 Pfam PF13391 HNH endonuclease 184 236 1.7E-8 T 05-07-2017 IPR003615 HNH nuclease K08M4_RS04405 fcc44c9615234d020aedb783ba212307 415 SUPERFAMILY SSF53850 21 414 5.98E-62 T 05-07-2017 K08M4_RS04405 fcc44c9615234d020aedb783ba212307 415 Pfam PF01547 Bacterial extracellular solute-binding protein 42 290 8.6E-19 T 05-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 K08M4_RS04405 fcc44c9615234d020aedb783ba212307 415 Gene3D G3DSA:3.40.190.10 141 339 2.5E-26 T 05-07-2017 K08M4_RS20805 f82ef50b7ebccae17d17583eb5376545 637 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 26 628 5.6E-178 T 05-07-2017 IPR011853 TRAP transporter, 4TM/12TM fusion protein K08M4_RS20805 f82ef50b7ebccae17d17583eb5376545 637 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 128 551 8.2E-83 T 05-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit K08M4_RS00430 68098215c274b052a8f43bdcaf9c9340 232 Pfam PF04340 Protein of unknown function, DUF484 7 219 2.7E-63 T 05-07-2017 IPR007435 Protein of unknown function DUF484 K08M4_RS12370 7a4a744f246694cd6f5d72fd46adf0f8 258 Pfam PF03883 Protein of unknown function (DUF328) 1 243 2.0E-94 T 05-07-2017 IPR005583 Peroxide stress protein YaaA K08M4_RS12370 7a4a744f246694cd6f5d72fd46adf0f8 258 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 38.798 T 05-07-2017 IPR005583 Peroxide stress protein YaaA K08M4_RS19925 1e3035d70d65ccae819cf780d9b7c827 220 Pfam PF09684 Phage tail protein (Tail_P2_I) 58 194 2.6E-5 T 05-07-2017 IPR006521 Tail protein I K08M4_RS08435 c98dac7cfcab384542aa081fb1f4036d 157 Pfam PF11163 Protein of unknown function (DUF2947) 3 154 1.2E-70 T 05-07-2017 IPR021334 Protein of unknown function DUF2947 K08M4_RS08165 f17883af197967da5eb4878ac6f5dc90 161 Pfam PF14317 YcxB-like protein 102 153 1.0E-5 T 05-07-2017 IPR025588 YcxB-like protein K08M4_RS10155 c90ac954a28fb9c0337e65cf62bc788f 478 Pfam PF01943 Polysaccharide biosynthesis protein 4 268 2.9E-13 T 05-07-2017 IPR002797 Polysaccharide biosynthesis protein GO:0016020 K08M4_RS03435 bc49ae486226c48e97448de1c08517b7 394 Pfam PF05940 NnrS protein 16 388 1.1E-105 T 05-07-2017 IPR010266 NnrS K08M4_RS04185 b7152ed60ce9d2b08b1befc7d1b79f71 162 Pfam PF03748 Flagellar basal body-associated protein FliL 61 162 9.9E-19 T 05-07-2017 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 K08M4_RS14270 e082f961348191496480947bb3ce6771 656 Pfam PF05170 AsmA family 3 584 1.4E-92 T 05-07-2017 IPR007844 AsmA K08M4_RS04280 7d77cfcce20d42ceaaea1c2548ff0b0f 170 Pfam PF10975 Protein of unknown function (DUF2802) 68 134 5.8E-22 T 05-07-2017 IPR021244 Protein of unknown function DUF2802 K08M4_RS16160 c6bdba9f0be5b3ae14633062c11bbc70 840 Pfam PF02687 FtsX-like permease family 714 829 8.0E-13 T 05-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 K08M4_RS16160 c6bdba9f0be5b3ae14633062c11bbc70 840 Pfam PF12704 MacB-like periplasmic core domain 488 681 4.1E-6 T 05-07-2017 IPR025857 MacB-like periplasmic core domain K08M4_RS09370 786074ca32d05a68becd3927d6b9698e 259 Pfam PF11150 Protein of unknown function (DUF2927) 31 230 1.1E-63 T 05-07-2017 IPR021323 Protein of unknown function DUF2927 K08M4_RS04745 c01adcf5ebf184b4bc4d7061b14e70ac 394 Pfam PF05940 NnrS protein 16 392 4.7E-106 T 05-07-2017 IPR010266 NnrS K08M4_RS10210 e8d11a136b1c9bc9be29e983e34e0540 146 Pfam PF09619 Type III secretion system lipoprotein chaperone (YscW) 36 137 1.1E-41 T 05-07-2017 K08M4_RS19900 e7fc33fa0f179765f345b5af22bc2d16 546 Gene3D G3DSA:2.40.50.230 276 340 6.3E-6 T 05-07-2017 IPR006531 Gp5 N-terminal K08M4_RS19900 e7fc33fa0f179765f345b5af22bc2d16 546 SUPERFAMILY SSF69255 250 341 1.07E-11 T 05-07-2017 K08M4_RS18310 d0c58409d50f92c330b180967752d705 306 Gene3D G3DSA:3.40.50.1980 132 198 2.8E-5 T 05-07-2017 K08M4_RS18310 d0c58409d50f92c330b180967752d705 306 SUPERFAMILY SSF53807 38 280 2.21E-15 T 05-07-2017 K08M4_RS14825 41117a5cb9dce4923c2d3332a597875f 263 Pfam PF07070 SpoOM protein 4 219 2.0E-75 T 05-07-2017 IPR009776 Sporulation stage 0, protein M K08M4_RS07445 9c48494592169d76f335afdf41cbef5d 248 Pfam PF03942 DTW domain 32 218 8.7E-42 T 05-07-2017 IPR005636 DTW K08M4_RS07445 9c48494592169d76f335afdf41cbef5d 248 SMART SM01144 29 224 1.0E-59 T 05-07-2017 IPR005636 DTW K08M4_RS19140 6ef9cfd588d00ef0013660679d6a7657 38 Pfam PF04886 PT repeat 3 37 9.5E-8 T 05-07-2017 IPR006970 PT repeat K08M4_RS04575 3af993dfe1e29a3e1f7e37d6be0dfac9 163 Pfam PF02674 Colicin V production protein 4 142 7.9E-38 T 05-07-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 K08M4_RS04320 b70644c9e9e1c50583f05a969e3b7b8f 162 Pfam PF03918 Cytochrome C biogenesis protein 12 153 2.9E-51 T 05-07-2017 IPR005616 CcmH/CycL/Ccl2/NrfF family K08M4_RS15820 5e728213facb9272013317d1eef4db5f 194 Pfam PF01810 LysE type translocator 17 187 8.2E-14 T 05-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 K08M4_RS17460 1484b1015d3c7bbb1842efd2cc796c50 123 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 27 116 6.0E-21 T 05-07-2017 IPR010221 VCBS repeat K08M4_RS19590 2519bec80bc9c04dd9cb5ea51962b9dc 784 Pfam PF06934 Fatty acid cis/trans isomerase (CTI) 102 783 8.9E-291 T 05-07-2017 IPR010706 Fatty acid cis-trans isomerase K08M4_RS11560 9e188f2755437c1f3b025fa05c32a008 157 Pfam PF11012 Protein of unknown function (DUF2850) 70 148 1.7E-32 T 05-07-2017 IPR021271 Protein of unknown function DUF2850 K08M4_RS20700 8cc4f7fbf482b5fa0ffefd0a8e576dd7 199 SUPERFAMILY SSF75217 1 198 5.75E-66 T 05-07-2017 IPR029028 Alpha/beta knot methyltransferases K08M4_RS20700 8cc4f7fbf482b5fa0ffefd0a8e576dd7 199 Gene3D G3DSA:3.40.1280.10 1 198 3.7E-78 T 05-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal K08M4_RS20700 8cc4f7fbf482b5fa0ffefd0a8e576dd7 199 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 1 197 4.3E-64 T 05-07-2017 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 K08M4_RS20700 8cc4f7fbf482b5fa0ffefd0a8e576dd7 199 Hamap MF_00587 tRNA (pseudouridine(54)-N(1))-methyltransferase [trmY]. 1 198 26.351 T 05-07-2017 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 K08M4_RS15930 665b9ddfb6184b26b2e2b7d8af8ba28c 489 Gene3D G3DSA:1.10.10.10 138 172 8.8E-4 T 05-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain K08M4_RS14120 afce1e9417d7578bf4b66bae9705d1d0 456 Pfam PF00860 Permease family 32 410 7.6E-20 T 05-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 K08M4_RS01070 a845769f06d0e633a52d3e2967244369 169 Pfam PF07813 LTXXQ motif family protein 44 149 3.0E-21 T 05-07-2017 IPR012899 LTXXQ motif family protein GO:0042597 K08M4_RS01070 a845769f06d0e633a52d3e2967244369 169 PIRSF PIRSF034445 1 160 1.2E-24 T 05-07-2017 IPR012899 LTXXQ motif family protein GO:0042597 K08M4_RS04510 d433a51017f83842dd84440089af8feb 87 Pfam PF08891 YfcL protein 4 84 1.1E-30 T 05-07-2017 IPR014987 Uncharacterised protein family YfcL K08M4_RS18750 ce0b544c6795c824919c1d6a5c25504b 305 Pfam PF13737 Transposase DDE domain 20 130 2.2E-43 T 05-07-2017 IPR025668 Transposase DDE domain K08M4_RS03545 038c672309d62ff1078d44ec68149b8c 254 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 182 199 - T 05-07-2017 IPR000540 Flagellar motor protein MotA, conserved site K08M4_RS03545 038c672309d62ff1078d44ec68149b8c 254 Pfam PF01618 MotA/TolQ/ExbB proton channel family 99 213 9.2E-23 T 05-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 K08M4_RS16755 36af7ab383e9a23ec020c7ab04b0a8e0 351 Pfam PF02628 Cytochrome oxidase assembly protein 15 323 1.5E-83 T 05-07-2017 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 K08M4_RS19975 4fd7b30316c308b2873d26402b175c2a 377 Pfam PF10758 Protein of unknown function (DUF2586) 3 371 3.7E-119 T 05-07-2017 IPR019694 Bacteriophage HP1, Orf23 K08M4_RS08455 8d9d40f63c6d37f2713969747375ec16 457 PIRSF PIRSF019381 1 457 5.4E-196 T 05-07-2017 IPR007413 Protein of unknown function DUF463, YcjX-like protein K08M4_RS08455 8d9d40f63c6d37f2713969747375ec16 457 Pfam PF04317 YcjX-like family, DUF463 20 456 8.7E-184 T 05-07-2017 IPR007413 Protein of unknown function DUF463, YcjX-like protein K08M4_RS06030 a76b39e2c8fe7d5c5f6534ed06f179ba 241 Pfam PF12119 Protein of unknown function (DUF3581) 1 216 7.9E-97 T 05-07-2017 IPR021974 Protein of unknown function DUF3581 K08M4_RS11475 0ae9c8723d9117f579f615c7b4e4871e 198 Hamap MF_00429 Na(+)-translocating NADH-quinone reductase subunit E [nqrE]. 1 198 29.847 T 05-07-2017 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 K08M4_RS11475 0ae9c8723d9117f579f615c7b4e4871e 198 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 196 3.0E-59 T 05-07-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 K08M4_RS11475 0ae9c8723d9117f579f615c7b4e4871e 198 PIRSF PIRSF006102 1 198 6.3E-66 T 05-07-2017 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 K08M4_RS11475 0ae9c8723d9117f579f615c7b4e4871e 198 TIGRFAM TIGR01940 nqrE: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit 2 197 1.8E-106 T 05-07-2017 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 K08M4_RS03250 16daeabfc12552ec485367a8906dc15a 203 Pfam PF10144 Bacterial virulence factor haemolysin 11 153 9.7E-37 T 05-07-2017 IPR019305 Uncharacterised protein family Smp K08M4_RS17285 26bee86e183d626bcf33a369166cd868 178 Pfam PF07811 TadE-like protein 10 51 3.2E-6 T 05-07-2017 IPR012495 TadE-like K08M4_RS10705 43cb55a1c90b4913c6e2848b89436b18 171 ProDom PD016359 TRANSMEMBRANE TOXS REGULATORY MEMBRANE PERIPLASMIC 14 171 2.0E-58 T 05-07-2017 K08M4_RS11460 a8621742e679474bd00414cddd1e42cc 84 Pfam PF04400 Protein of unknown function (DUF539) 22 62 9.4E-21 T 05-07-2017 IPR007495 (Na+)-NQR maturation factor NqrM K08M4_RS20720 4b5557f2d206569921b4eadf1354612d 366 Pfam PF03773 Predicted permease 9 362 1.8E-60 T 05-07-2017 IPR005524 Predicted permease DUF318 K08M4_RS02740 95c1aa08d392e18627fd48e8db4aaf65 264 Pfam PF01578 Cytochrome C assembly protein 38 262 2.1E-44 T 05-07-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 K08M4_RS01945 18f74743d7d432fb1bfc6ffd901c510f 366 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 2 345 1.1E-117 T 05-07-2017 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 K08M4_RS01945 18f74743d7d432fb1bfc6ffd901c510f 366 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 343 2.2E-71 T 05-07-2017 IPR005495 Permease LptG/LptF-related GO:0016021 K08M4_RS06355 53bd2f03a8779e1e021c9d830a0093bc 334 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 165 2.6E-26 T 05-07-2017 IPR007404 LexA-binding, inner membrane-associated putative hydrolase K08M4_RS05320 af9db9eab121aacbb5560f6f7472bb56 56 Pfam PF10689 Protein of unknown function (DUF2496) 9 51 1.5E-23 T 05-07-2017 IPR019630 Protein of unknown function DUF2496, YbaM-related K08M4_RS11090 b4f67e1f7b91c68047da7a17bd26fb04 415 TIGRFAM TIGR03503 TIGR03503: TIGR03503 family protein 25 399 3.3E-129 T 05-07-2017 IPR020010 Conserved hypothetical protein CHP03503 K08M4_RS20020 26e326d7b7d2651cbbaa685a80f5b63a 205 Pfam PF10320 Serpentine type 7TM GPCR chemoreceptor Srsx 29 99 1.8E-4 T 05-07-2017 IPR019424 Serpentine type 7TM GPCR chemoreceptor Srsx K08M4_RS17235 1344de58ed3a5ce98f8246a700bb3981 152 Pfam PF01478 Type IV leader peptidase family 16 112 1.6E-8 T 05-07-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 K08M4_RS08050 557952592b319bac7dac889b9539ed8c 166 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 20 157 6.3E-15 T 05-07-2017 IPR009936 Protein of unknown function DUF1468 K08M4_RS05230 efa71a985f6a0a3725288e70ce32a954 526 Pfam PF04293 SpoVR like protein 33 463 4.0E-177 T 05-07-2017 IPR007390 Sporulation stage V, protein R K08M4_RS00140 c6c54de8e130268752d34c1785d1e379 193 Pfam PF13358 DDE superfamily endonuclease 23 161 1.2E-26 T 05-07-2017 K08M4_RS01220 c33ae45b4d5c607f7a0eba580a9e4667 82 Pfam PF12292 Protein of unknown function (DUF3624) 1 79 2.1E-34 T 05-07-2017 IPR022072 Protein of unknown function DUF3624 K08M4_RS21620 1894b5360ad3cf923788478379702ca0 114 Pfam PF12614 Ribosome recycling factor 3 111 5.3E-20 T 05-07-2017 IPR022253 Ribosome recycling factor. bacterial K08M4_RS17770 da65914c73697c1c0aee189fb0a6909e 226 Pfam PF06468 Spondin_N 41 160 9.7E-10 T 05-07-2017 IPR009465 Spondin, N-terminal Reactome: R-HSA-5083635|Reactome: R-HSA-5173214 K08M4_RS15160 e68297f65d290d82eb5c587482f44643 222 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 58 161 1.5E-13 T 05-07-2017 IPR010319 Transglutaminase-like cysteine peptidase, predicted K08M4_RS17290 2843c9d4bde136d4035eca09c0b0bb73 194 Pfam PF16964 Putative tight adherence pilin protein F 3 178 4.2E-25 T 05-07-2017 IPR031582 Putative tight adherence pilin protein F K08M4_RS07745 b62b2a79d7df25dca51e0ac5fb16ece0 200 Pfam PF11185 Protein of unknown function (DUF2971) 64 136 7.0E-9 T 05-07-2017 IPR021352 Protein of unknown function DUF2971 K08M4_RS08060 52e6cd1c8c7d2cef96a3e0f20eba359c 252 Pfam PF01925 Sulfite exporter TauE/SafE 6 247 9.9E-36 T 05-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 K08M4_RS10180 a3ac7fd32c466f5fbb8d8fb6ba094588 242 Pfam PF03591 AzlC protein 21 159 5.3E-36 T 05-07-2017 IPR011606 Branched-chain amino acid transport, permease K08M4_RS16405 75c66b66898a44cc26509a6d6848f869 224 Pfam PF06912 Protein of unknown function (DUF1275) 13 208 1.8E-28 T 05-07-2017 IPR010699 Protein of unknown function DUF1275 K08M4_RS16000 d27df760fcbe584ccae8e7406bc98f1d 559 Pfam PF13584 Oxygen tolerance 21 464 7.5E-69 T 05-07-2017 IPR025738 Aerotolerance-related protein BatD K08M4_RS19015 d624def318447c37ee8889d4e2c4c50e 30 Pfam PF11665 Protein of unknown function (DUF3265) 3 30 5.8E-12 T 05-07-2017 IPR021681 Protein of unknown function DUF3265 K08M4_RS07755 3f36e178a269b09aa0810d4558be62dc 102 Pfam PF12321 Protein of unknown function (DUF3634) 2 101 2.0E-40 T 05-07-2017 IPR022090 Protein of unknown function DUF3634 K08M4_RS07655 3c14fb031af79274614a9665933c96d9 58 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 7 45 1.7E-9 T 05-07-2017 IPR008621 Cbb3-type cytochrome oxidase component K08M4_RS06755 4915324a82c6d1df1e0163a61f6e14c1 141 Pfam PF10980 Protein of unknown function (DUF2787) 20 126 4.0E-15 T 05-07-2017 IPR021248 Protein of unknown function DUF2787 K08M4_RS19230 1875f4ca30891419665d84e081d7fad2 460 Pfam PF13584 Oxygen tolerance 71 301 3.5E-25 T 05-07-2017 IPR025738 Aerotolerance-related protein BatD K08M4_RS15515 688718196f99808e1d1b2aa5a047f658 78 Pfam PF04325 Protein of unknown function (DUF465) 29 75 9.1E-11 T 05-07-2017 IPR007420 Protein of unknown function DUF465 K08M4_RS08385 80566e75d9065a5d96cc7c885c9426d6 437 Pfam PF06629 MltA-interacting protein MipA 49 239 1.5E-24 T 05-07-2017 IPR010583 MltA-interacting MipA K08M4_RS21395 d27849dc57182344745520b48bf4817f 154 Pfam PF11012 Protein of unknown function (DUF2850) 47 126 7.2E-30 T 05-07-2017 IPR021271 Protein of unknown function DUF2850 K08M4_RS12990 b9db48ec50a37b28bb9e89cfaa50723d 161 Pfam PF12821 Threonine/Serine exporter, ThrE 17 151 1.6E-35 T 05-07-2017 IPR024528 Threonine/Serine exporter, ThrE K08M4_RS21605 f3fc1b4354ef3a4242be89b7de5ffdb9 180 Pfam PF12915 Protein of unknown function (DUF3833) 18 179 5.6E-66 T 05-07-2017 IPR024409 Protein of unknown function DUF3833 K08M4_RS16930 40462a95b550ec089682daa42a95ce93 185 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 39 175 1.4E-19 T 05-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component K08M4_RS07345 40b841c77f5c724017e9c7a77ba98a41 458 Pfam PF04932 O-Antigen ligase 241 378 1.4E-19 T 05-07-2017 IPR007016 O-antigen ligase-related K08M4_RS19055 2371072a30cdba60406a32852c76809b 286 SUPERFAMILY SSF51069 131 277 3.66E-8 T 05-07-2017 IPR001148 Alpha carbonic anhydrase K08M4_RS02145 c8aee56be63decd93a4f28699eb24c90 185 Pfam PF02325 YGGT family 109 173 5.0E-19 T 05-07-2017 IPR003425 CCB3/YggT GO:0016020 K08M4_RS02145 c8aee56be63decd93a4f28699eb24c90 185 Pfam PF02325 YGGT family 10 77 2.1E-20 T 05-07-2017 IPR003425 CCB3/YggT GO:0016020 K08M4_RS09375 7f7b335d0ae6b8d6b10be96202e830d8 129 Pfam PF11042 Protein of unknown function (DUF2750) 23 122 1.7E-36 T 05-07-2017 IPR021284 Protein of unknown function DUF2750