locus-tag	class	description
YZOS03_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
YZOS03_RS00010	COG0592	DNA-directed DNA polymerase activity
YZOS03_RS00020	COG0187	DNA topoisomerase II activity
YZOS03_RS00030	COG0071	Belongs to the small heat shock protein (HSP20) family
YZOS03_RS00035	COG3977	Valine--pyruvate aminotransferase
YZOS03_RS00040	COG0366	Alpha amylase catalytic
YZOS03_RS00055	COG2119	membrane
YZOS03_RS00065	COG0425	Belongs to the sulfur carrier protein TusA family
YZOS03_RS00080	COG0604	alcohol dehydrogenase
YZOS03_RS00085	COG0183	Belongs to the thiolase family
YZOS03_RS00095	COG1739	Uncharacterized protein family UPF0029
YZOS03_RS00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YZOS03_RS00150	COG2132	Multicopper oxidase
YZOS03_RS00170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YZOS03_RS00175	COG2104	thiamine diphosphate biosynthetic process
YZOS03_RS00190	COG0006	proline dipeptidase activity
YZOS03_RS00190	COG0006	proline dipeptidase activity
YZOS03_RS00220	COG3220	belongs to the UPF0276 family
YZOS03_RS00230	COG0210	DNA helicase
YZOS03_RS00235	COG0405	Gamma-glutamyltransferase
YZOS03_RS00240	COG1280	lysine exporter protein (LysE YggA)
YZOS03_RS00250	COG2962	Rard protein
YZOS03_RS00255	COG0514	ATP-dependent DNA helicase (RecQ)
YZOS03_RS00265	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YZOS03_RS00275	COG0248	Ppx GppA phosphatase
YZOS03_RS00280	COG0513	Belongs to the DEAD box helicase family
YZOS03_RS00285	COG3118	belongs to the thioredoxin family
YZOS03_RS00300	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
YZOS03_RS00305	COG0633	Ferredoxin
YZOS03_RS00345	COG3071	HemY protein
YZOS03_RS00355	COG1587	Uroporphyrinogen-III synthase
YZOS03_RS00360	COG0181	hydroxymethylbilane synthase activity
YZOS03_RS00370	COG1965	Belongs to the frataxin family
YZOS03_RS00380	COG0019	diaminopimelate decarboxylase activity
YZOS03_RS00395	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YZOS03_RS00400	COG1011	Hydrolase
YZOS03_RS00405	COG2199	diguanylate cyclase activity
YZOS03_RS00405	COG3287	FIST C domain
YZOS03_RS00405	COG2200	EAL domain
YZOS03_RS00410	COG3148	PFAM DTW domain containing protein
YZOS03_RS00425	COG0561	phosphatase activity
YZOS03_RS00430	COG2267	carboxylic ester hydrolase activity
YZOS03_RS00435	COG1280	lysine exporter protein (LysE YggA)
YZOS03_RS00445	COG0640	Transcriptional regulator
YZOS03_RS00450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
YZOS03_RS00490	COG2095	MarC family integral membrane protein
YZOS03_RS00500	COG0742	ribosomal rna small subunit methyltransferase
YZOS03_RS00505	COG0552	protein localization to endoplasmic reticulum
YZOS03_RS00505	COG0552	protein localization to endoplasmic reticulum
YZOS03_RS00510	COG2884	Cell division ATP-binding protein ftsE
YZOS03_RS00515	COG2177	Part of the ABC transporter FtsEX involved in
YZOS03_RS00525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YZOS03_RS00530	COG0705	Rhomboid family
YZOS03_RS00535	COG1580	Controls the rotational direction of flagella during chemotaxis
YZOS03_RS00540	COG3161	chorismate lyase activity
YZOS03_RS00545	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
YZOS03_RS00550	COG2937	Belongs to the GPAT DAPAT family
YZOS03_RS00555	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
YZOS03_RS00560	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
YZOS03_RS00565	COG0534	Mate efflux family protein
YZOS03_RS00570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YZOS03_RS00590	COG4206	TonB-dependent receptor
YZOS03_RS00665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YZOS03_RS00675	COG0812	UDP-N-acetylmuramate dehydrogenase activity
YZOS03_RS00680	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
YZOS03_RS00680	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
YZOS03_RS00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YZOS03_RS00715	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YZOS03_RS00720	COG0250	Participates in transcription elongation, termination and antitermination
YZOS03_RS00735	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
YZOS03_RS00740	COG0222	ribosome binding
YZOS03_RS00745	COG0085	RNA polymerase activity
YZOS03_RS00750	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YZOS03_RS00755	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
YZOS03_RS00760	COG2816	NAD+ diphosphatase activity
YZOS03_RS00765	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
YZOS03_RS00770	COG1573	uracil-dna glycosylase
YZOS03_RS00780	COG3068	Protein conserved in bacteria
YZOS03_RS00785	COG1253	flavin adenine dinucleotide binding
YZOS03_RS00800	COG0151	Belongs to the GarS family
YZOS03_RS00810	COG0789	Transcriptional regulator
YZOS03_RS00815	COG3710	Transcriptional regulator
YZOS03_RS00820	COG0531	amino acid
YZOS03_RS00825	COG1982	Orn Lys Arg decarboxylase major
YZOS03_RS00875	COG0488	(ABC) transporter
YZOS03_RS00885	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YZOS03_RS00890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YZOS03_RS00895	COG2264	protein methyltransferase activity
YZOS03_RS00900	COG0439	Biotin carboxylase
YZOS03_RS00905	COG0511	ligase activity, forming carbon-carbon bonds
YZOS03_RS00910	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
YZOS03_RS00915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YZOS03_RS00930	COG2814	Major facilitator Superfamily
YZOS03_RS00955	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YZOS03_RS00965	COG3263	regulation of cellular component size
YZOS03_RS00975	COG4232	protein-disulfide reductase activity
YZOS03_RS00980	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YZOS03_RS00985	COG1027	Aspartate ammonia-lyase
YZOS03_RS00990	COG3030	protein affecting phage T7 exclusion by the F plasmid
YZOS03_RS00995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YZOS03_RS01005	COG2205	protein histidine kinase activity
YZOS03_RS01010	COG0745	RESPONSE REGULATOR receiver
YZOS03_RS01015	COG3678	ATP-independent chaperone mediated protein folding
YZOS03_RS01025	COG0205	6-phosphofructokinase activity
YZOS03_RS01030	COG0534	Mate efflux family protein
YZOS03_RS01040	COG0459	protein refolding
YZOS03_RS01050	COG1285	pathogenesis
YZOS03_RS01055	COG1509	lysine 2,3-aminomutase activity
YZOS03_RS01070	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YZOS03_RS01075	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YZOS03_RS01080	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YZOS03_RS01085	COG1053	succinate dehydrogenase
YZOS03_RS01090	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
YZOS03_RS01110	COG4942	peptidase
YZOS03_RS01115	COG1045	serine acetyltransferase
YZOS03_RS01120	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
YZOS03_RS01125	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
YZOS03_RS01130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YZOS03_RS01135	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YZOS03_RS01145	COG0471	metal ion transport
YZOS03_RS01150	COG0688	phosphatidylethanolamine metabolic process
YZOS03_RS01155	COG1162	GTPase activity
YZOS03_RS01160	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YZOS03_RS01225	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YZOS03_RS01230	COG0802	atpase or kinase
YZOS03_RS01240	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YZOS03_RS01245	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
YZOS03_RS01255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YZOS03_RS01260	COG0330	HflC and HflK could
YZOS03_RS01265	COG0330	HflC and HflK could
YZOS03_RS01270	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YZOS03_RS01275	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
YZOS03_RS01285	COG1017	nitric oxide dioxygenase activity
YZOS03_RS01285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YZOS03_RS01290	COG1959	2 iron, 2 sulfur cluster binding
YZOS03_RS01295	COG0557	exoribonuclease II activity
YZOS03_RS01300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YZOS03_RS01305	COG0546	phosphoglycolate phosphatase activity
YZOS03_RS01310	COG0180	Tryptophanyl-tRNA synthetase
YZOS03_RS01325	COG0512	Glutamine amidotransferase of anthranilate synthase
YZOS03_RS01330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YZOS03_RS01350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YZOS03_RS01355	COG3954	Phosphoribulokinase
YZOS03_RS01365	COG0429	hydrolase of the alpha beta-hydrolase fold
YZOS03_RS01375	COG0488	(ABC) transporter
YZOS03_RS01380	COG2249	NAD(P)H dehydrogenase (quinone) activity
YZOS03_RS01395	COG1047	Peptidyl-prolyl cis-trans
YZOS03_RS01400	COG1446	asparaginase
YZOS03_RS01415	COG0545	Peptidyl-prolyl cis-trans isomerase
YZOS03_RS01420	COG2964	Protein conserved in bacteria
YZOS03_RS01425	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YZOS03_RS01430	COG2923	Belongs to the DsrF TusC family
YZOS03_RS01450	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YZOS03_RS01455	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YZOS03_RS01470	COG0281	malic enzyme
YZOS03_RS01475	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
YZOS03_RS01480	COG0626	cystathionine gamma-synthase activity
YZOS03_RS01485	COG0527	aspartate kinase activity
YZOS03_RS01485	COG0460	homoserine dehydrogenase
YZOS03_RS01490	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
YZOS03_RS01500	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
YZOS03_RS01510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YZOS03_RS01520	COG0137	argininosuccinate synthase activity
YZOS03_RS01525	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
YZOS03_RS01525	COG0165	Argininosuccinate lyase
YZOS03_RS01540	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YZOS03_RS01540	COG0678	peroxiredoxin activity
YZOS03_RS01550	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YZOS03_RS01580	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
YZOS03_RS01585	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
YZOS03_RS01595	COG0338	D12 class N6 adenine-specific DNA methyltransferase
YZOS03_RS01600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YZOS03_RS01605	COG0360	Binds together with S18 to 16S ribosomal RNA
YZOS03_RS01610	COG2965	DNA replication, synthesis of RNA primer
YZOS03_RS01635	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YZOS03_RS01640	COG0432	Pfam Uncharacterised protein family UPF0047
YZOS03_RS01645	COG0166	Belongs to the GPI family
YZOS03_RS01655	COG0735	belongs to the Fur family
YZOS03_RS01660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YZOS03_RS01680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YZOS03_RS01685	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YZOS03_RS01690	COG0175	sulfate reduction
YZOS03_RS01750	COG1410	methionine synthase
YZOS03_RS01750	COG0646	methionine synthase
YZOS03_RS01755	COG0527	aspartate kinase activity
YZOS03_RS01760	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YZOS03_RS01770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YZOS03_RS01785	COG0629	single-stranded DNA binding
YZOS03_RS01790	COG2200	EAL domain
YZOS03_RS01790	COG2199	diguanylate cyclase activity
YZOS03_RS01810	COG1450	Type ii and iii secretion system protein
YZOS03_RS01815	COG3409	Peptidoglycan-binding domain 1 protein
YZOS03_RS01815	COG3267	Type II secretory pathway component ExeA
YZOS03_RS01825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YZOS03_RS01830	COG1459	type II secretion system
YZOS03_RS01840	COG2165	general secretion pathway protein
YZOS03_RS01880	COG1077	Cell shape determining protein MreB Mrl
YZOS03_RS01885	COG1792	Involved in formation and maintenance of cell shape
YZOS03_RS01890	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YZOS03_RS01895	COG0424	maF-like protein
YZOS03_RS01905	COG3164	Protein of unknown function
YZOS03_RS01910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YZOS03_RS01920	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
YZOS03_RS01925	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YZOS03_RS01935	COG0564	pseudouridine synthase activity
YZOS03_RS01940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YZOS03_RS01945	COG3028	Belongs to the UPF0307 family
YZOS03_RS01950	COG0312	modulator of DNA gyrase
YZOS03_RS01955	COG2239	Acts as a magnesium transporter
YZOS03_RS01960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YZOS03_RS01965	COG1660	Displays ATPase and GTPase activities
YZOS03_RS01970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YZOS03_RS01975	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YZOS03_RS01985	COG1137	ATPase activity
YZOS03_RS01990	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YZOS03_RS02000	COG0517	IMP dehydrogenase activity
YZOS03_RS02000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YZOS03_RS02010	COG1127	ABC transporter
YZOS03_RS02015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YZOS03_RS02020	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YZOS03_RS02025	COG2854	intermembrane phospholipid transfer
YZOS03_RS02035	COG5007	Belongs to the BolA IbaG family
YZOS03_RS02040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
YZOS03_RS02045	COG0204	Acyl-transferase
YZOS03_RS02050	COG0251	oxidation-reduction process
YZOS03_RS02055	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
YZOS03_RS02060	COG0540	Belongs to the ATCase OTCase family
YZOS03_RS02090	COG0456	acetyltransferase
YZOS03_RS02100	COG0525	valine-tRNA ligase activity
YZOS03_RS02105	COG2927	DNA polymerase III (CHI subunit)
YZOS03_RS02110	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
YZOS03_RS02115	COG0795	lipopolysaccharide-transporting ATPase activity
YZOS03_RS02120	COG0795	lipopolysaccharide-transporting ATPase activity
YZOS03_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
YZOS03_RS02145	COG0726	polysaccharide deacetylase
YZOS03_RS02150	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YZOS03_RS02155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YZOS03_RS02160	COG1447	Phosphotransferase system cellobiose-specific component IIA
YZOS03_RS02165	COG1486	melibiose metabolic process
YZOS03_RS02170	COG3394	polysaccharide catabolic process
YZOS03_RS02175	COG1609	Transcriptional regulator
YZOS03_RS02180	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YZOS03_RS02300	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
YZOS03_RS02310	COG0220	tRNA (guanine-N7-)-methyltransferase activity
YZOS03_RS02320	COG2066	Belongs to the glutaminase family
YZOS03_RS02325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YZOS03_RS02330	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YZOS03_RS02340	COG1872	DUF167
YZOS03_RS02345	COG0762	integral membrane protein
YZOS03_RS02350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YZOS03_RS02355	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YZOS03_RS02370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
YZOS03_RS02375	COG1678	Uncharacterized ACR, COG1678
YZOS03_RS02380	COG0189	ligase activity
YZOS03_RS02385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YZOS03_RS02390	COG2356	endonuclease I
YZOS03_RS02405	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
YZOS03_RS02410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YZOS03_RS02415	COG0583	DNA-binding transcription factor activity
YZOS03_RS02420	COG4771	TonB-dependent receptor
YZOS03_RS02435	COG0191	fructose-bisphosphate aldolase activity
YZOS03_RS02440	COG0668	transmembrane transport
YZOS03_RS02455	COG0583	DNA-binding transcription factor activity
YZOS03_RS02465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YZOS03_RS02470	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YZOS03_RS02475	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YZOS03_RS02485	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
YZOS03_RS02490	COG3079	Belongs to the UPF0149 family
YZOS03_RS02495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YZOS03_RS02500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YZOS03_RS02520	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
YZOS03_RS02530	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YZOS03_RS02535	COG1595	DNA-templated transcription, initiation
YZOS03_RS02550	COG3086	response to oxidative stress
YZOS03_RS02555	COG0481	GTPase activity
YZOS03_RS02560	COG0681	Belongs to the peptidase S26 family
YZOS03_RS02570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
YZOS03_RS02575	COG1381	Involved in DNA repair and RecF pathway recombination
YZOS03_RS02580	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YZOS03_RS02585	COG0736	holo-[acyl-carrier-protein] synthase activity
YZOS03_RS02595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YZOS03_RS02600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YZOS03_RS02605	COG3956	TIGRFAM MazG family protein
YZOS03_RS02610	COG0504	CTP synthase activity
YZOS03_RS02615	COG0148	phosphopyruvate hydratase activity
YZOS03_RS02620	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
YZOS03_RS02625	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
YZOS03_RS02630	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
YZOS03_RS02640	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
YZOS03_RS02645	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
YZOS03_RS02655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YZOS03_RS02660	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
YZOS03_RS02665	COG1546	Belongs to the CinA family
YZOS03_RS02670	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
YZOS03_RS02675	COG2137	regulation of response to DNA damage stimulus
YZOS03_RS02680	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YZOS03_RS02685	COG0527	aspartate kinase activity
YZOS03_RS02745	COG3630	sodium ion export across plasma membrane
YZOS03_RS02750	COG0511	ligase activity, forming carbon-carbon bonds
YZOS03_RS02750	COG5016	pyruvate
YZOS03_RS02755	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
YZOS03_RS02765	COG1238	metal cluster binding
YZOS03_RS02770	COG0612	Peptidase, M16
YZOS03_RS02785	COG1854	S-ribosylhomocysteine lyase activity
YZOS03_RS02790	COG4536	flavin adenine dinucleotide binding
YZOS03_RS02795	COG4137	Cytochrome C assembly protein
YZOS03_RS02800	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YZOS03_RS02805	COG0228	four-way junction DNA binding
YZOS03_RS02810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
YZOS03_RS02825	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
YZOS03_RS02830	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
YZOS03_RS02835	COG0237	dephospho-CoA kinase activity
YZOS03_RS02845	COG1459	type II secretion system
YZOS03_RS02850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YZOS03_RS02855	COG4969	Belongs to the N-Me-Phe pilin family
YZOS03_RS02860	COG0157	Belongs to the NadC ModD family
YZOS03_RS02870	COG2186	Transcriptional regulator
YZOS03_RS02875	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YZOS03_RS02880	COG0508	dehydrogenase complex catalyzes the overall conversion of
YZOS03_RS02885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YZOS03_RS02900	COG0288	reversible hydration of carbon dioxide
YZOS03_RS02920	COG0842	Transport permease protein
YZOS03_RS02925	COG1560	Kdo2-lipid A biosynthetic process
YZOS03_RS02930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
YZOS03_RS02935	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
YZOS03_RS02940	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YZOS03_RS02950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YZOS03_RS02960	COG1489	DNA binding
YZOS03_RS02965	COG1643	Atp-dependent helicase
YZOS03_RS02970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YZOS03_RS02975	COG1752	Esterase of the alpha-beta hydrolase superfamily
YZOS03_RS02980	COG1049	propionate catabolic process, 2-methylcitrate cycle
YZOS03_RS02995	COG0004	ammonium transporteR
YZOS03_RS03000	COG1840	ABC-type Fe3 transport system, periplasmic component
YZOS03_RS03010	COG3842	ATPase activity
YZOS03_RS03015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YZOS03_RS03030	COG2971	BadF BadG BcrA BcrD
YZOS03_RS03040	COG4608	Belongs to the ABC transporter superfamily
YZOS03_RS03045	COG0444	Belongs to the ABC transporter superfamily
YZOS03_RS03050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YZOS03_RS03060	COG0747	negative chemotaxis
YZOS03_RS03065	COG2205	protein histidine kinase activity
YZOS03_RS03065	COG0784	Response regulator, receiver
YZOS03_RS03075	COG0628	permease
YZOS03_RS03100	COG0739	heme binding
YZOS03_RS03105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
YZOS03_RS03115	COG2027	D-alanyl-D-alanine carboxypeptidase
YZOS03_RS03120	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YZOS03_RS03125	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YZOS03_RS03130	COG1534	Rna-binding protein
YZOS03_RS03135	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
YZOS03_RS03140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YZOS03_RS03145	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YZOS03_RS03150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YZOS03_RS03155	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YZOS03_RS03170	COG0779	Required for maturation of 30S ribosomal subunits
YZOS03_RS03175	COG0195	Participates in both transcription termination and antitermination
YZOS03_RS03180	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YZOS03_RS03185	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
YZOS03_RS03190	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
YZOS03_RS03195	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
YZOS03_RS03200	COG1185	polyribonucleotide nucleotidyltransferase activity
YZOS03_RS03215	COG0534	Mate efflux family protein
YZOS03_RS03220	COG0826	peptidase U32
YZOS03_RS03225	COG0826	peptidase U32
YZOS03_RS03235	COG3154	lipid carrier protein
YZOS03_RS03240	COG3153	acetyltransferase
YZOS03_RS03270	COG0084	hydrolase, TatD family'
YZOS03_RS03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YZOS03_RS03280	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YZOS03_RS03285	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
YZOS03_RS03290	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
YZOS03_RS03295	COG0813	purine-nucleoside phosphorylase activity
YZOS03_RS03305	COG0560	Phosphoserine phosphatase
YZOS03_RS03315	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
YZOS03_RS03320	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YZOS03_RS03325	COG0583	DNA-binding transcription factor activity
YZOS03_RS03335	COG1022	Amp-dependent synthetase and ligase
YZOS03_RS03375	COG0583	DNA-binding transcription factor activity
YZOS03_RS03380	COG1609	Transcriptional regulator
YZOS03_RS03400	COG0598	Magnesium transport protein CorA
YZOS03_RS03405	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YZOS03_RS03410	COG1349	DNA-binding transcription factor activity
YZOS03_RS03415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YZOS03_RS03420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YZOS03_RS03425	COG2271	Major facilitator Superfamily
YZOS03_RS03430	COG0584	glycerophosphoryl diester phosphodiesterase
YZOS03_RS03435	COG2171	N-acyltransferase activity
YZOS03_RS03450	COG3141	response to X-ray
YZOS03_RS03470	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YZOS03_RS03475	COG1074	ATP-dependent DNA helicase activity
YZOS03_RS03480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YZOS03_RS03500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YZOS03_RS03500	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
YZOS03_RS03510	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YZOS03_RS03515	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YZOS03_RS03520	COG2166	iron-sulfur cluster assembly
YZOS03_RS03525	COG3706	GGDEF domain
YZOS03_RS03530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YZOS03_RS03535	COG0693	protein deglycase activity
YZOS03_RS03540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YZOS03_RS03560	COG1595	DNA-templated transcription, initiation
YZOS03_RS03580	COG3056	Lipoprotein
YZOS03_RS03585	COG2813	Specifically methylates the guanine in position
YZOS03_RS03590	COG0271	Belongs to the BolA IbaG family
YZOS03_RS03595	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YZOS03_RS03600	COG1805	sodium ion transport
YZOS03_RS03605	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YZOS03_RS03610	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YZOS03_RS03615	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YZOS03_RS03620	COG2871	sodium ion transport
YZOS03_RS03625	COG1477	protein flavinylation
YZOS03_RS03645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
YZOS03_RS03650	COG0514	ATP-dependent DNA helicase (RecQ)
YZOS03_RS03655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YZOS03_RS03670	COG0733	neurotransmitter:sodium symporter activity
YZOS03_RS03690	COG0442	prolyl-tRNA aminoacylation
YZOS03_RS03695	COG1720	tRNA m6t6A37 methyltransferase activity
YZOS03_RS03700	COG0254	rRNA binding
YZOS03_RS03710	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
YZOS03_RS03720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YZOS03_RS03735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YZOS03_RS03740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YZOS03_RS03775	COG0564	pseudouridine synthase activity
YZOS03_RS03785	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
YZOS03_RS03790	COG0024	Methionine aminopeptidase
YZOS03_RS03795	COG0052	Belongs to the universal ribosomal protein uS2 family
YZOS03_RS03800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
YZOS03_RS03805	COG0528	UMP kinase activity
YZOS03_RS03810	COG0233	cytoplasmic translational termination
YZOS03_RS03815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
YZOS03_RS03820	COG0575	Belongs to the CDS family
YZOS03_RS03825	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
YZOS03_RS03830	COG0750	zinc metalloprotease
YZOS03_RS03840	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
YZOS03_RS03845	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YZOS03_RS03855	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YZOS03_RS03860	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YZOS03_RS03870	COG0587	DNA-directed DNA polymerase activity
YZOS03_RS03875	COG0825	malonyl-CoA metabolic process
YZOS03_RS03890	COG0347	Belongs to the P(II) protein family
YZOS03_RS03895	COG3021	interspecies interaction between organisms
YZOS03_RS03905	COG1388	LysM domain
YZOS03_RS03905	COG0741	lytic transglycosylase activity
YZOS03_RS03910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YZOS03_RS03915	COG2226	methyltransferase
YZOS03_RS03920	COG0328	RNA-DNA hybrid ribonuclease activity
YZOS03_RS03955	COG1960	acyl-CoA dehydrogenase activity
YZOS03_RS03960	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
YZOS03_RS03965	COG0121	glutamine amidotransferase
YZOS03_RS03970	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YZOS03_RS03975	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
YZOS03_RS03980	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
YZOS03_RS03985	COG2233	PERMEase
YZOS03_RS04005	COG1393	Belongs to the ArsC family
YZOS03_RS04010	COG4783	chaperone-mediated protein folding
YZOS03_RS04030	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YZOS03_RS04040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YZOS03_RS04045	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YZOS03_RS04060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YZOS03_RS04065	COG1393	Belongs to the ArsC family
YZOS03_RS04090	COG2837	iron assimilation
YZOS03_RS04095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YZOS03_RS04100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YZOS03_RS04105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YZOS03_RS04110	COG1334	flagellar protein FlaG
YZOS03_RS04115	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
YZOS03_RS04125	COG1516	flagellar protein fliS
YZOS03_RS04145	COG1677	Flagellar hook-basal body complex protein FliE
YZOS03_RS04155	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
YZOS03_RS04210	COG1987	bacterial-type flagellum assembly
YZOS03_RS04215	COG1684	flagellar biosynthetic protein fliR
YZOS03_RS04250	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YZOS03_RS04255	COG2198	Histidine kinase
YZOS03_RS04255	COG0784	Response regulator, receiver
YZOS03_RS04255	COG0643	Histidine kinase
YZOS03_RS04260	COG2201	protein-glutamate methylesterase activity
YZOS03_RS04265	COG1192	Involved in chromosome partitioning
YZOS03_RS04275	COG0835	chemotaxis
YZOS03_RS04285	COG4133	protoheme IX ABC transporter activity
YZOS03_RS04290	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YZOS03_RS04295	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YZOS03_RS04300	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YZOS03_RS04305	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
YZOS03_RS04310	COG1138	Cytochrome C-type biogenesis protein
YZOS03_RS04315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YZOS03_RS04325	COG4235	cytochrome complex assembly
YZOS03_RS04325	COG3088	subunit of a heme lyase
YZOS03_RS04335	COG2067	long-chain fatty acid transport protein
YZOS03_RS04355	COG0183	Belongs to the thiolase family
YZOS03_RS04360	COG1250	3-hydroxyacyl-CoA dehydrogenase
YZOS03_RS04360	COG1024	Enoyl-CoA hydratase
YZOS03_RS04375	COG2062	phosphohistidine phosphatase, SixA
YZOS03_RS04380	COG2840	Smr protein MutS2
YZOS03_RS04385	COG2890	protein-(glutamine-N5) methyltransferase activity
YZOS03_RS04390	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
YZOS03_RS04395	COG2860	membrane
YZOS03_RS04400	COG3101	peptidyl-lysine hydroxylation
YZOS03_RS04410	COG0431	NADPH-dependent FMN reductase
YZOS03_RS04415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YZOS03_RS04415	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
YZOS03_RS04420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YZOS03_RS04425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YZOS03_RS04430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YZOS03_RS04440	COG0101	tRNA pseudouridine synthase activity
YZOS03_RS04445	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
YZOS03_RS04450	COG0285	dihydrofolate synthase activity
YZOS03_RS04455	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YZOS03_RS04460	COG1286	toxin biosynthetic process
YZOS03_RS04465	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YZOS03_RS04470	COG0583	DNA-binding transcription factor activity
YZOS03_RS04475	COG0745	RESPONSE REGULATOR receiver
YZOS03_RS04480	COG2832	Protein of unknown function (DUF454)
YZOS03_RS04485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
YZOS03_RS04500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
YZOS03_RS04505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YZOS03_RS04515	COG2261	transglycosylase associated protein
YZOS03_RS04520	COG2983	Belongs to the UPF0260 family
YZOS03_RS04525	COG0668	transmembrane transport
YZOS03_RS04530	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YZOS03_RS04535	COG0346	lactoylglutathione lyase activity
YZOS03_RS04545	COG1785	Belongs to the alkaline phosphatase family
YZOS03_RS04560	COG2226	methyltransferase
YZOS03_RS04570	COG0676	glucose-6-phosphate 1-epimerase activity
YZOS03_RS04575	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
YZOS03_RS04580	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YZOS03_RS04590	COG3139	Protein of unknown function (DUF1315)
YZOS03_RS04595	COG0252	asparaginase activity
YZOS03_RS04600	COG0616	signal peptide processing
YZOS03_RS04605	COG0446	pyridine nucleotide-disulphide oxidoreductase
YZOS03_RS04605	COG1902	pentaerythritol trinitrate reductase activity
YZOS03_RS04615	COG0778	Nitroreductase
YZOS03_RS04620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YZOS03_RS04635	COG0123	including yeast histone deacetylase and acetoin utilization protein
YZOS03_RS04650	COG3082	Protein of unknown function (DUF1414)
YZOS03_RS04655	COG3081	Nucleoid-associated protein
YZOS03_RS04670	COG1757	Na H antiporter
YZOS03_RS04675	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YZOS03_RS04680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YZOS03_RS04685	COG2095	MarC family integral membrane protein
YZOS03_RS04690	COG1012	belongs to the aldehyde dehydrogenase family
YZOS03_RS04690	COG1454	alcohol dehydrogenase
YZOS03_RS04710	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YZOS03_RS04720	COG2056	Na+-H+ antiporter family
YZOS03_RS04725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YZOS03_RS04730	COG2885	chlorophyll binding
YZOS03_RS04740	COG0346	lactoylglutathione lyase activity
YZOS03_RS04745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YZOS03_RS04750	COG4660	Part of a membrane complex involved in electron transport
YZOS03_RS04755	COG4659	FMN binding
YZOS03_RS04760	COG4658	electron transport chain
YZOS03_RS04770	COG2878	Part of a membrane complex involved in electron transport
YZOS03_RS04775	COG4657	Part of a membrane complex involved in electron transport
YZOS03_RS04780	COG1882	Formate acetyltransferase
YZOS03_RS04790	COG0556	nucleotide-excision repair
YZOS03_RS04795	COG2204	response regulator
YZOS03_RS04800	COG2198	Histidine kinase
YZOS03_RS04805	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YZOS03_RS04810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YZOS03_RS04815	COG0521	Mo-molybdopterin cofactor biosynthetic process
YZOS03_RS04820	COG0315	cyclic pyranopterin monophosphate synthase activity
YZOS03_RS04825	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YZOS03_RS04830	COG0314	molybdopterin synthase activity
YZOS03_RS04840	COG0601	transmembrane transport
YZOS03_RS04845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YZOS03_RS04850	COG0444	Belongs to the ABC transporter superfamily
YZOS03_RS04860	COG0435	Glutathione S-transferase
YZOS03_RS04870	COG0280	phosphate acetyltransferase
YZOS03_RS04870	COG0857	belongs to the CobB CobQ family
YZOS03_RS04875	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
YZOS03_RS04880	COG3092	negative regulation of chromosome organization
YZOS03_RS04890	COG4120	Belongs to the binding-protein-dependent transport system permease family
YZOS03_RS04895	COG1122	ATPase activity
YZOS03_RS04900	COG0366	Alpha amylase catalytic
YZOS03_RS04905	COG3706	GGDEF domain
YZOS03_RS04910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YZOS03_RS04915	COG3318	Belongs to the UPF0149 family
YZOS03_RS04915	COG3012	SEC-C Motif Domain Protein
YZOS03_RS04920	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
YZOS03_RS04925	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YZOS03_RS04930	COG2186	Transcriptional regulator
YZOS03_RS04940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YZOS03_RS04940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YZOS03_RS04950	COG0572	uridine kinase
YZOS03_RS04960	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
YZOS03_RS04965	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
YZOS03_RS04970	COG0659	secondary active sulfate transmembrane transporter activity
YZOS03_RS04975	COG1530	ribonuclease E activity
YZOS03_RS04980	COG0564	pseudouridine synthase activity
YZOS03_RS04985	COG0424	maF-like protein
YZOS03_RS04990	COG1399	metal-binding, possibly nucleic acid-binding protein
YZOS03_RS05000	COG0416	fatty acid biosynthetic process
YZOS03_RS05005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YZOS03_RS05035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YZOS03_RS05040	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
YZOS03_RS05045	COG0470	DNA polymerase III
YZOS03_RS05050	COG0084	hydrolase, TatD family'
YZOS03_RS05055	COG1263	PTS System
YZOS03_RS05055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YZOS03_RS05070	COG0733	neurotransmitter:sodium symporter activity
YZOS03_RS05085	COG4667	esterase of the alpha-beta hydrolase superfamily
YZOS03_RS05090	COG0469	pyruvate kinase activity
YZOS03_RS05095	COG1940	carbohydrate kinase activity
YZOS03_RS05100	COG0784	Response regulator, receiver
YZOS03_RS05100	COG0835	chemotaxis
YZOS03_RS05105	COG0587	DNA-directed DNA polymerase activity
YZOS03_RS05120	COG1028	Short-chain dehydrogenase reductase Sdr
YZOS03_RS05125	COG0616	signal peptide processing
YZOS03_RS05130	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
YZOS03_RS05135	COG0539	negative regulation of cytoplasmic translation
YZOS03_RS05145	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YZOS03_RS05150	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YZOS03_RS05160	COG4166	transmembrane transport
YZOS03_RS05180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YZOS03_RS05180	COG3008	intermembrane lipid transfer
YZOS03_RS05185	COG2995	paraquat-inducible protein a
YZOS03_RS05190	COG3258	Cytochrome c
YZOS03_RS05195	COG2863	cytochrome
YZOS03_RS05230	COG4232	protein-disulfide reductase activity
YZOS03_RS05235	COG3118	belongs to the thioredoxin family
YZOS03_RS05245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YZOS03_RS05260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YZOS03_RS05270	COG1136	(ABC) transporter
YZOS03_RS05270	COG0577	efflux transmembrane transporter activity
YZOS03_RS05280	COG1136	(ABC) transporter
YZOS03_RS05280	COG0577	efflux transmembrane transporter activity
YZOS03_RS05330	COG3850	Histidine kinase
YZOS03_RS05330	COG5002	protein histidine kinase activity
YZOS03_RS05335	COG0745	RESPONSE REGULATOR receiver
YZOS03_RS05340	COG0463	Glycosyl transferase, family 2
YZOS03_RS05345	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
YZOS03_RS05370	COG1032	radical SAM domain protein
YZOS03_RS05375	COG5001	Diguanylate cyclase
YZOS03_RS05390	COG0583	DNA-binding transcription factor activity
YZOS03_RS05395	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
YZOS03_RS05405	COG2350	Protein conserved in bacteria
YZOS03_RS05415	COG2917	probably involved in intracellular septation
YZOS03_RS05435	COG1301	dicarboxylic acid transport
YZOS03_RS05440	COG0318	PFAM AMP-dependent synthetase and ligase
YZOS03_RS05445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YZOS03_RS05450	COG0159	tryptophan synthase activity
YZOS03_RS05460	COG0134	indole-3-glycerol-phosphate synthase activity
YZOS03_RS05460	COG0135	phosphoribosylanthranilate isomerase activity
YZOS03_RS05470	COG0512	Glutamine amidotransferase of anthranilate synthase
YZOS03_RS05475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
YZOS03_RS05485	COG0613	PHP domain protein
YZOS03_RS05490	COG0009	L-threonylcarbamoyladenylate synthase
YZOS03_RS05500	COG1187	pseudouridine synthase activity
YZOS03_RS05520	COG0417	DNA replication proofreading
YZOS03_RS05525	COG2197	response regulator
YZOS03_RS05530	COG0322	excinuclease ABC activity
YZOS03_RS05570	COG0019	diaminopimelate decarboxylase activity
YZOS03_RS05600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YZOS03_RS05605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YZOS03_RS05625	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
YZOS03_RS05635	COG0437	4 iron, 4 sulfur cluster binding
YZOS03_RS05640	COG3301	Polysulphide reductase, NrfD
YZOS03_RS05645	COG1138	Cytochrome C-type biogenesis protein
YZOS03_RS05655	COG3088	subunit of a heme lyase
YZOS03_RS05655	COG4235	cytochrome complex assembly
YZOS03_RS05665	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YZOS03_RS05690	COG2989	Protein conserved in bacteria
YZOS03_RS05695	COG3108	Peptidase M15
YZOS03_RS05700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YZOS03_RS05715	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
YZOS03_RS05745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YZOS03_RS05750	COG0840	transmembrane signaling receptor activity
YZOS03_RS05770	COG1448	Aminotransferase
YZOS03_RS05785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YZOS03_RS05795	COG0017	Asparaginyl-tRNA synthetase
YZOS03_RS05800	COG0840	transmembrane signaling receptor activity
YZOS03_RS05805	COG0720	synthase
YZOS03_RS05815	COG2200	EAL domain
YZOS03_RS05820	COG1760	l-serine dehydratase
YZOS03_RS05825	COG0814	amino acid
YZOS03_RS05830	COG0494	nUDIX hydrolase
YZOS03_RS05840	COG0784	Response regulator, receiver
YZOS03_RS05840	COG2205	protein histidine kinase activity
YZOS03_RS05860	COG3106	COG3106 Predicted ATPase
YZOS03_RS05865	COG3768	UPF0283 membrane protein
YZOS03_RS05875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YZOS03_RS05945	COG1192	Involved in chromosome partitioning
YZOS03_RS06310	COG0232	Belongs to the dGTPase family. Type 2 subfamily
YZOS03_RS06480	COG1715	Restriction endonuclease
YZOS03_RS06550	COG2026	Addiction module toxin, RelE StbE family
YZOS03_RS06735	COG0110	maltose O-acetyltransferase activity
YZOS03_RS06740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YZOS03_RS06765	COG5507	3-demethylubiquinone-9 3-methyltransferase
YZOS03_RS06770	COG1280	lysine exporter protein (LysE YggA)
YZOS03_RS06775	COG1280	lysine exporter protein (LysE YggA)
YZOS03_RS06785	COG0729	surface antigen
YZOS03_RS06790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YZOS03_RS06795	COG2272	Belongs to the type-B carboxylesterase lipase family
YZOS03_RS06820	COG2985	domain, Protein
YZOS03_RS06830	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
YZOS03_RS06845	COG0583	DNA-binding transcription factor activity
YZOS03_RS06860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YZOS03_RS06875	COG3290	protein histidine kinase activity
YZOS03_RS06880	COG4565	transcriptional regulatory protein
YZOS03_RS06890	COG2207	Transcriptional regulator
YZOS03_RS06895	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YZOS03_RS06900	COG0363	glucosamine-6-phosphate deaminase activity
YZOS03_RS06905	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
YZOS03_RS06925	COG3284	Transcriptional regulator
YZOS03_RS06930	COG1012	belongs to the aldehyde dehydrogenase family
YZOS03_RS07000	COG4669	(LipO)protein
YZOS03_RS07020	COG3177	Filamentation induced by cAMP protein fic
YZOS03_RS07050	COG2207	Transcriptional regulator
YZOS03_RS07055	COG4792	protein secretion
YZOS03_RS07060	COG4791	protein targeting
YZOS03_RS07065	COG4794	Type iii secretion
YZOS03_RS07070	COG4790	Type iii secretion
YZOS03_RS07140	COG0457	Tetratricopeptide repeat
YZOS03_RS07155	COG2358	TRAP transporter, solute receptor (TAXI family
YZOS03_RS07160	COG0730	response to heat
YZOS03_RS07195	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
YZOS03_RS07200	COG0372	Belongs to the citrate synthase family
YZOS03_RS07210	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YZOS03_RS07215	COG2828	Protein conserved in bacteria
YZOS03_RS07240	COG0561	phosphatase activity
YZOS03_RS07245	COG0602	queuosine metabolic process
YZOS03_RS07250	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
YZOS03_RS07265	COG0583	DNA-binding transcription factor activity
YZOS03_RS07270	COG0583	DNA-binding transcription factor activity
YZOS03_RS07285	COG0583	DNA-binding transcription factor activity
YZOS03_RS07300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YZOS03_RS07305	COG0765	amino acid transport
YZOS03_RS07310	COG1126	abc transporter atp-binding protein
YZOS03_RS07315	COG0646	methionine synthase
YZOS03_RS07315	COG1410	methionine synthase
YZOS03_RS07330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YZOS03_RS07335	COG1335	isochorismatase
YZOS03_RS07355	COG2814	Major facilitator Superfamily
YZOS03_RS07360	COG0583	DNA-binding transcription factor activity
YZOS03_RS07370	COG0583	DNA-binding transcription factor activity
YZOS03_RS07375	COG0656	L-ascorbic acid biosynthetic process
YZOS03_RS07390	COG2203	Gaf domain
YZOS03_RS07390	COG2199	diguanylate cyclase activity
YZOS03_RS07415	COG2885	chlorophyll binding
YZOS03_RS07440	COG1254	Belongs to the acylphosphatase family
YZOS03_RS07445	COG2920	part of a sulfur-relay system
YZOS03_RS07455	COG0670	Belongs to the BI1 family
YZOS03_RS07460	COG1126	abc transporter atp-binding protein
YZOS03_RS07465	COG0765	amino acid transport
YZOS03_RS07470	COG4597	amino acid ABC transporter
YZOS03_RS07475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YZOS03_RS07485	COG1666	GTP binding
YZOS03_RS07490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YZOS03_RS07515	COG3008	intermembrane lipid transfer
YZOS03_RS07520	COG2995	paraquat-inducible protein a
YZOS03_RS07525	COG1132	(ABC) transporter
YZOS03_RS07530	COG1956	GAF domain-containing protein
YZOS03_RS07535	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
YZOS03_RS07550	COG0308	aminopeptidase N
YZOS03_RS07560	COG2902	Dehydrogenase
YZOS03_RS07565	COG0167	dihydroorotate dehydrogenase activity
YZOS03_RS07575	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
YZOS03_RS07575	COG0116	Belongs to the methyltransferase superfamily
YZOS03_RS07585	COG0488	(ABC) transporter
YZOS03_RS07600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YZOS03_RS07605	COG1067	ATP-dependent peptidase activity
YZOS03_RS07610	COG3120	sequence-specific DNA binding
YZOS03_RS07635	COG4128	Pfam Zonular occludens toxin
YZOS03_RS07805	COG0784	Response regulator, receiver
YZOS03_RS07805	COG2205	protein histidine kinase activity
YZOS03_RS07820	COG3278	Belongs to the heme-copper respiratory oxidase family
YZOS03_RS07835	COG2010	Cytochrome c
YZOS03_RS07845	COG2217	Heavy metal translocating P-type atpase
YZOS03_RS07860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YZOS03_RS07865	COG0589	response to stress
YZOS03_RS07890	COG3842	ATPase activity
YZOS03_RS07900	COG1177	transmembrane transport
YZOS03_RS07910	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YZOS03_RS07915	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YZOS03_RS07925	COG0004	ammonium transporteR
YZOS03_RS07950	COG0437	4 iron, 4 sulfur cluster binding
YZOS03_RS07955	COG0243	molybdopterin cofactor binding
YZOS03_RS07955	COG3383	formate dehydrogenase (NAD+) activity
YZOS03_RS07965	COG3381	protein complex oligomerization
YZOS03_RS07985	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
YZOS03_RS07990	COG0488	(ABC) transporter
YZOS03_RS07995	COG4191	Histidine kinase
YZOS03_RS08000	COG2204	response regulator
YZOS03_RS08015	COG3842	ATPase activity
YZOS03_RS08020	COG0746	molybdenum cofactor guanylyltransferase activity
YZOS03_RS08025	COG0303	'Molybdopterin
YZOS03_RS08035	COG1940	carbohydrate kinase activity
YZOS03_RS08040	COG3148	PFAM DTW domain containing protein
YZOS03_RS08070	COG0791	NLP P60 protein
YZOS03_RS08080	COG3706	GGDEF domain
YZOS03_RS08100	COG0307	riboflavin synthase, alpha
YZOS03_RS08105	COG0534	Mate efflux family protein
YZOS03_RS08115	COG1793	dna ligase
YZOS03_RS08145	COG2204	response regulator
YZOS03_RS08155	COG0438	transferase activity, transferring glycosyl groups
YZOS03_RS08185	COG0438	transferase activity, transferring glycosyl groups
YZOS03_RS08190	COG1215	transferase activity, transferring glycosyl groups
YZOS03_RS08195	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
YZOS03_RS08205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YZOS03_RS08220	COG1643	Atp-dependent helicase
YZOS03_RS08225	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
YZOS03_RS08270	COG0443	Heat shock 70 kDa protein
YZOS03_RS08275	COG0443	Heat shock 70 kDa protein
YZOS03_RS08300	COG0583	DNA-binding transcription factor activity
YZOS03_RS08320	COG1132	(ABC) transporter
YZOS03_RS08335	COG4774	siderophore transport
YZOS03_RS08345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YZOS03_RS08350	COG1120	ATPase activity
YZOS03_RS08365	COG0814	amino acid
YZOS03_RS08375	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YZOS03_RS08385	COG0861	Integral membrane protein TerC family
YZOS03_RS08395	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YZOS03_RS08400	COG1328	CTP reductase activity
YZOS03_RS08430	COG0471	metal ion transport
YZOS03_RS08455	COG4702	Belongs to the UPF0303 family
YZOS03_RS08460	COG0673	inositol 2-dehydrogenase activity
YZOS03_RS08465	COG1349	DNA-binding transcription factor activity
YZOS03_RS08480	COG1538	Outer membrane efflux protein
YZOS03_RS08510	COG3119	arylsulfatase activity
YZOS03_RS08525	COG0641	radical SAM
YZOS03_RS08540	COG3119	arylsulfatase activity
YZOS03_RS08545	COG0527	aspartate kinase activity
YZOS03_RS08550	COG0662	Cupin 2, conserved barrel domain protein
YZOS03_RS08555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YZOS03_RS08560	COG0456	acetyltransferase
YZOS03_RS08565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YZOS03_RS08585	COG4176	ABC-type proline glycine betaine transport system permease component
YZOS03_RS08590	COG2113	Glycine betaine
YZOS03_RS08595	COG1368	sulfuric ester hydrolase activity
YZOS03_RS08620	COG1115	amino acid carrier protein
YZOS03_RS08635	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YZOS03_RS08640	COG1560	Kdo2-lipid A biosynthetic process
YZOS03_RS08655	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
YZOS03_RS08660	COG3063	Type IV pilus biogenesis stability protein PilW
YZOS03_RS08700	COG2315	Protein conserved in bacteria
YZOS03_RS08705	COG1846	Transcriptional regulator
YZOS03_RS08715	COG2200	EAL domain
YZOS03_RS08720	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YZOS03_RS08725	COG1012	belongs to the aldehyde dehydrogenase family
YZOS03_RS08730	COG2957	Belongs to the agmatine deiminase family
YZOS03_RS08740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YZOS03_RS08745	COG1012	belongs to the aldehyde dehydrogenase family
YZOS03_RS08750	COG1917	Cupin 2, conserved barrel domain protein
YZOS03_RS08750	COG1396	sequence-specific DNA binding
YZOS03_RS08755	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
YZOS03_RS08760	COG0174	glutamine synthetase
YZOS03_RS08765	COG1757	Na H antiporter
YZOS03_RS08780	COG1742	UPF0060 membrane protein
YZOS03_RS08805	COG3755	Protein conserved in bacteria
YZOS03_RS08855	COG0307	riboflavin synthase, alpha
YZOS03_RS08870	COG1028	Short-chain dehydrogenase reductase Sdr
YZOS03_RS09025	COG1783	phage Terminase large subunit
YZOS03_RS09090	COG4221	oxidoreductase activity
YZOS03_RS09095	COG2207	Transcriptional regulator
YZOS03_RS09195	COG0625	glutathione transferase activity
YZOS03_RS09205	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
YZOS03_RS09215	COG2195	Cleaves the N-terminal amino acid of tripeptides
YZOS03_RS09230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YZOS03_RS09250	COG3291	Pkd domain containing protein
YZOS03_RS09260	COG1177	transmembrane transport
YZOS03_RS09270	COG3842	ATPase activity
YZOS03_RS09275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YZOS03_RS09280	COG2423	ornithine cyclodeaminase activity
YZOS03_RS09295	COG3938	Belongs to the proline racemase family
YZOS03_RS09330	COG1451	nucleotide metabolic process
YZOS03_RS09340	COG0583	DNA-binding transcription factor activity
YZOS03_RS09360	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
YZOS03_RS09365	COG4139	cobalamin transport
YZOS03_RS09370	COG2988	succinylglutamate desuccinylase activity
YZOS03_RS09390	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
YZOS03_RS09400	COG0702	epimerase
YZOS03_RS09405	COG1823	symporter activity
YZOS03_RS09410	COG2925	Exonuclease
YZOS03_RS09415	COG1380	Effector of murein hydrolase LrgA
YZOS03_RS09420	COG1346	cytolysis
YZOS03_RS09425	COG0295	cytidine deaminase activity
YZOS03_RS09430	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
YZOS03_RS09435	COG0500	methyltransferase
YZOS03_RS09445	COG0776	regulation of translation
YZOS03_RS09455	COG0072	phenylalanine-tRNA ligase activity
YZOS03_RS09455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YZOS03_RS09460	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
YZOS03_RS09495	COG0393	Putative heavy-metal-binding
YZOS03_RS09505	COG0291	Belongs to the bacterial ribosomal protein bL35 family
YZOS03_RS09515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
YZOS03_RS09530	COG2188	Transcriptional regulator
YZOS03_RS09535	COG1228	amidohydrolase
YZOS03_RS09540	COG0010	Belongs to the arginase family
YZOS03_RS09545	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
YZOS03_RS09550	COG2986	histidine ammonia-lyase
YZOS03_RS09565	COG0277	FAD linked oxidase domain protein
YZOS03_RS09565	COG0247	lactate metabolic process
YZOS03_RS09600	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
YZOS03_RS09620	COG0281	malic enzyme
YZOS03_RS09625	COG2949	membrane
YZOS03_RS09630	COG0471	metal ion transport
YZOS03_RS09655	COG0492	ferredoxin-NADP+ reductase activity
YZOS03_RS09660	COG4988	ABC transporter
YZOS03_RS09665	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YZOS03_RS09675	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
YZOS03_RS09685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YZOS03_RS09685	COG4191	Histidine kinase
YZOS03_RS09700	COG3070	regulator of competence-specific genes
YZOS03_RS09710	COG2431	L-lysine efflux transmembrane transporter activity
YZOS03_RS09720	COG0076	glutamate decarboxylase activity
YZOS03_RS09725	COG1737	Transcriptional regulator
YZOS03_RS09735	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YZOS03_RS09740	COG3273	potassium ion transport
YZOS03_RS09740	COG2985	domain, Protein
YZOS03_RS09745	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
YZOS03_RS09750	COG1960	acyl-CoA dehydrogenase activity
YZOS03_RS09760	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YZOS03_RS09780	COG0534	Mate efflux family protein
YZOS03_RS09785	COG0702	epimerase
YZOS03_RS09795	COG2814	Major facilitator Superfamily
YZOS03_RS09800	COG1187	pseudouridine synthase activity
YZOS03_RS09805	COG1061	Type III restriction enzyme res subunit
YZOS03_RS09825	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
YZOS03_RS09845	COG3313	Fe-S protein
YZOS03_RS09855	COG4134	Bacterial extracellular solute-binding protein
YZOS03_RS09860	COG4135	transport system, permease component
YZOS03_RS09865	COG4136	ATPase activity
YZOS03_RS09870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YZOS03_RS09880	COG3604	Transcriptional regulator
YZOS03_RS09885	COG1151	hydroxylamine reductase activity
YZOS03_RS09890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YZOS03_RS09900	COG0564	pseudouridine synthase activity
YZOS03_RS09905	COG0733	neurotransmitter:sodium symporter activity
YZOS03_RS09915	COG0626	cystathionine gamma-synthase activity
YZOS03_RS09920	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
YZOS03_RS09925	COG5380	lipid catabolic process
YZOS03_RS09930	COG2818	Glycosylase
YZOS03_RS09950	COG1983	PspC domain protein
YZOS03_RS09960	COG1842	Phage shock protein A
YZOS03_RS09965	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YZOS03_RS09980	COG4171	peptide transport system, permease
YZOS03_RS09990	COG4172	Belongs to the ABC transporter superfamily
YZOS03_RS10000	COG1227	inorganic diphosphatase activity
YZOS03_RS10015	COG0243	molybdopterin cofactor binding
YZOS03_RS10020	COG3005	denitrification pathway
YZOS03_RS10025	COG4459	periplasmic nitrate reductase
YZOS03_RS10030	COG0390	transport system, permease component
YZOS03_RS10040	COG2116	formate transmembrane transporter activity
YZOS03_RS10065	COG1434	Gram-negative-bacterium-type cell wall biogenesis
YZOS03_RS10070	COG1435	thymidine kinase activity
YZOS03_RS10075	COG0215	cysteine-tRNA ligase activity
YZOS03_RS10080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YZOS03_RS10090	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
YZOS03_RS10095	COG3012	SEC-C Motif Domain Protein
YZOS03_RS10100	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YZOS03_RS10100	COG0140	phosphoribosyl-ATP diphosphatase activity
YZOS03_RS10110	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
YZOS03_RS10115	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
YZOS03_RS10120	COG0131	Imidazoleglycerol-phosphate dehydratase
YZOS03_RS10120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YZOS03_RS10130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YZOS03_RS10140	COG1757	Na H antiporter
YZOS03_RS10150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YZOS03_RS10165	COG2915	High frequency lysogenization protein hflD homolog
YZOS03_RS10170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YZOS03_RS10180	COG2268	Band 7 protein
YZOS03_RS10190	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YZOS03_RS10205	COG0300	oxidoreductase activity
YZOS03_RS10225	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YZOS03_RS10245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
YZOS03_RS10250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
YZOS03_RS10260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YZOS03_RS10270	COG1674	ftsk spoiiie
YZOS03_RS10280	COG0686	Belongs to the AlaDH PNT family
YZOS03_RS10290	COG0583	DNA-binding transcription factor activity
YZOS03_RS10315	COG3568	Endonuclease Exonuclease Phosphatase
YZOS03_RS10340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YZOS03_RS10345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YZOS03_RS10365	COG1271	oxidase subunit
YZOS03_RS10370	COG1294	oxidase, subunit
YZOS03_RS10395	COG0754	glutathionylspermidine amidase activity
YZOS03_RS10405	COG3766	membrane
YZOS03_RS10415	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
YZOS03_RS10420	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YZOS03_RS10425	COG2885	chlorophyll binding
YZOS03_RS10430	COG0823	Involved in the tonB-independent uptake of proteins
YZOS03_RS10445	COG0811	peptide transport
YZOS03_RS10450	COG0824	Thioesterase
YZOS03_RS10460	COG4890	Cyd operon protein YbgT
YZOS03_RS10465	COG1294	oxidase, subunit
YZOS03_RS10470	COG1271	oxidase subunit
YZOS03_RS10475	COG2255	four-way junction helicase activity
YZOS03_RS10480	COG0632	four-way junction helicase activity
YZOS03_RS10485	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
YZOS03_RS10490	COG0217	transcriptional regulatory protein
YZOS03_RS10510	COG0500	methyltransferase
YZOS03_RS10515	COG4067	protein conserved in archaea
YZOS03_RS10515	COG0189	ligase activity
YZOS03_RS10535	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
YZOS03_RS10540	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
YZOS03_RS10545	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
YZOS03_RS10550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YZOS03_RS10555	COG1434	Gram-negative-bacterium-type cell wall biogenesis
YZOS03_RS10560	COG0745	RESPONSE REGULATOR receiver
YZOS03_RS10565	COG3381	protein complex oligomerization
YZOS03_RS10570	COG1609	Transcriptional regulator
YZOS03_RS10575	COG3070	regulator of competence-specific genes
YZOS03_RS10595	COG0297	glycogen (starch) synthase activity
YZOS03_RS10600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
YZOS03_RS10605	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YZOS03_RS10625	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
YZOS03_RS10630	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
YZOS03_RS10635	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YZOS03_RS10640	COG0542	response to heat
YZOS03_RS10645	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
YZOS03_RS10650	COG1278	Cold shock
YZOS03_RS10660	COG1187	pseudouridine synthase activity
YZOS03_RS10665	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
YZOS03_RS10670	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YZOS03_RS10675	COG1199	ATP-dependent helicase activity
YZOS03_RS10680	COG0730	response to heat
YZOS03_RS10685	COG3923	Primosomal replication protein n
YZOS03_RS10695	COG0708	Exodeoxyribonuclease III
YZOS03_RS10735	COG1882	Formate acetyltransferase
YZOS03_RS10745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YZOS03_RS10755	COG3013	Belongs to the UPF0304 family
YZOS03_RS10760	COG2766	serine protein kinase
YZOS03_RS10765	COG2718	Belongs to the UPF0229 family
YZOS03_RS10770	COG2719	SpoVR family
YZOS03_RS10790	COG1132	(ABC) transporter
YZOS03_RS10795	COG2333	competence protein COMEC
YZOS03_RS10795	COG0658	competence protein
YZOS03_RS10805	COG4591	ABC-type transport system involved in lipoprotein release permease component
YZOS03_RS10815	COG4591	ABC-type transport system involved in lipoprotein release permease component
YZOS03_RS10825	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YZOS03_RS10840	COG1252	NADH dehydrogenase
YZOS03_RS10845	COG3150	esterase
YZOS03_RS10870	COG0537	adenosine 5'-monophosphoramidase activity
YZOS03_RS10895	COG0516	GMP reductase activity
YZOS03_RS10895	COG0517	IMP dehydrogenase activity
YZOS03_RS10900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YZOS03_RS10925	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YZOS03_RS10930	COG1946	Acyl-CoA thioesterase
YZOS03_RS10940	COG1522	sequence-specific DNA binding
YZOS03_RS10945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YZOS03_RS10960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YZOS03_RS10965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YZOS03_RS11010	COG0477	Major facilitator Superfamily
YZOS03_RS11015	COG2855	membrane
YZOS03_RS11035	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YZOS03_RS11045	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
YZOS03_RS11050	COG1169	isochorismate synthase
YZOS03_RS11055	COG0436	Aminotransferase
YZOS03_RS11060	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
YZOS03_RS11065	COG0232	Belongs to the dGTPase family. Type 2 subfamily
YZOS03_RS11080	COG1555	photosystem II stabilization
YZOS03_RS11085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YZOS03_RS11090	COG0776	regulation of translation
YZOS03_RS11095	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YZOS03_RS11100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
YZOS03_RS11110	COG0544	peptidyl-prolyl cis-trans isomerase activity
YZOS03_RS11135	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
YZOS03_RS11140	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
YZOS03_RS11145	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YZOS03_RS11150	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
YZOS03_RS11165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YZOS03_RS11170	COG0569	domain protein
YZOS03_RS11175	COG0513	Belongs to the DEAD box helicase family
YZOS03_RS11210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YZOS03_RS11215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YZOS03_RS11230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YZOS03_RS11235	COG1216	Glycosyl transferase, family 2
YZOS03_RS11240	COG2986	histidine ammonia-lyase
YZOS03_RS11265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YZOS03_RS11275	COG1028	Short-chain dehydrogenase reductase Sdr
YZOS03_RS11290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
YZOS03_RS11295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YZOS03_RS11305	COG2951	lytic endotransglycosylase activity
YZOS03_RS11310	COG3100	YcgL domain-containing protein
YZOS03_RS11315	COG0850	regulation of cytokinetic process
YZOS03_RS11320	COG2894	cell division
YZOS03_RS11325	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YZOS03_RS11330	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YZOS03_RS11335	COG0318	PFAM AMP-dependent synthetase and ligase
YZOS03_RS11340	COG2267	carboxylic ester hydrolase activity
YZOS03_RS11345	COG3065	identical protein binding
YZOS03_RS11355	COG1214	PFAM Peptidase M22, glycoprotease
YZOS03_RS11360	COG1199	ATP-dependent helicase activity
YZOS03_RS11365	COG0788	formyltetrahydrofolate deformylase activity
YZOS03_RS11380	COG3102	Protein conserved in bacteria
YZOS03_RS11385	COG0018	arginyl-trna synthetase
YZOS03_RS11410	COG1918	ferrous iron import across plasma membrane
YZOS03_RS11420	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YZOS03_RS11425	COG1121	(ABC) transporter
YZOS03_RS11430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YZOS03_RS11440	COG0045	succinate-CoA ligase (ADP-forming) activity
YZOS03_RS11445	COG0508	dehydrogenase complex catalyzes the overall conversion of
YZOS03_RS11450	COG0567	Dehydrogenase, E1 component
YZOS03_RS11455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YZOS03_RS11460	COG1053	succinate dehydrogenase
YZOS03_RS11465	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YZOS03_RS11480	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YZOS03_RS11490	COG0033	Phosphoglucomutase
YZOS03_RS11495	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YZOS03_RS11500	COG0596	Alpha beta hydrolase
YZOS03_RS11510	COG0716	FMN binding
YZOS03_RS11520	COG0735	belongs to the Fur family
YZOS03_RS11525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YZOS03_RS11530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YZOS03_RS11530	COG1263	PTS System
YZOS03_RS11530	COG2190	(PTS) system
YZOS03_RS11535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YZOS03_RS11540	COG1846	Transcriptional regulator
YZOS03_RS11540	COG1940	carbohydrate kinase activity
YZOS03_RS11545	COG4651	solute:proton antiporter activity
YZOS03_RS11545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YZOS03_RS11550	COG0367	asparagine synthase
YZOS03_RS11555	COG0250	Participates in transcription elongation, termination and antitermination
YZOS03_RS11560	COG3104	oligopeptide transport
YZOS03_RS11565	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
YZOS03_RS11575	COG0326	Molecular chaperone. Has ATPase activity
YZOS03_RS11580	COG3710	Transcriptional regulator
YZOS03_RS11600	COG0622	Phosphoesterase
YZOS03_RS11630	COG1090	epimerase
YZOS03_RS11635	COG0300	oxidoreductase activity
YZOS03_RS11640	COG3118	belongs to the thioredoxin family
YZOS03_RS11645	COG0457	Tetratricopeptide repeat
YZOS03_RS11645	COG3118	belongs to the thioredoxin family
YZOS03_RS11650	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YZOS03_RS11655	COG1215	transferase activity, transferring glycosyl groups
YZOS03_RS11660	COG1215	transferase activity, transferring glycosyl groups
YZOS03_RS11665	COG1192	Involved in chromosome partitioning
YZOS03_RS11685	COG2194	sulfuric ester hydrolase activity
YZOS03_RS11690	COG0330	HflC and HflK could
YZOS03_RS11710	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YZOS03_RS11715	COG3115	cell septum assembly
YZOS03_RS11720	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
YZOS03_RS11725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YZOS03_RS11730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YZOS03_RS11735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YZOS03_RS11740	COG2190	(PTS) system
YZOS03_RS11745	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YZOS03_RS11750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YZOS03_RS11755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YZOS03_RS11760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YZOS03_RS11770	COG1705	Flagellar rod assembly protein muramidase FlgJ
YZOS03_RS11770	COG3951	Flagellar rod assembly protein muramidase FlgJ
YZOS03_RS11775	COG1706	bacterial-type flagellum-dependent cell motility
YZOS03_RS11780	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
YZOS03_RS11790	COG4787	bacterial-type flagellum-dependent cell motility
YZOS03_RS11795	COG1749	Flagellar hook protein flgE
YZOS03_RS11805	COG1558	bacterial-type flagellum-dependent cell motility
YZOS03_RS11810	COG1815	bacterial-type flagellum-dependent cell motility
YZOS03_RS11815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YZOS03_RS11820	COG0784	Response regulator, receiver
YZOS03_RS11820	COG0835	chemotaxis
YZOS03_RS11875	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
YZOS03_RS11885	COG2217	Heavy metal translocating P-type atpase
YZOS03_RS11885	COG2608	mercury ion transmembrane transporter activity
YZOS03_RS11925	COG2840	Smr protein MutS2
YZOS03_RS11930	COG1187	pseudouridine synthase activity
YZOS03_RS11935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YZOS03_RS11945	COG2877	3-deoxy-8-phosphooctulonate synthase activity
YZOS03_RS11950	COG2912	Transglutaminase-like superfamily
YZOS03_RS11955	COG3094	Invasion gene expression up-regulator, SirB
YZOS03_RS11960	COG2890	protein-(glutamine-N5) methyltransferase activity
YZOS03_RS11970	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
YZOS03_RS11975	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
YZOS03_RS11980	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
YZOS03_RS11985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YZOS03_RS11990	COG0193	aminoacyl-tRNA hydrolase activity
YZOS03_RS11995	COG0012	GTP binding
YZOS03_RS12100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YZOS03_RS12105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YZOS03_RS12110	COG1702	phosphate starvation-inducible protein PhoH
YZOS03_RS12115	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
YZOS03_RS12120	COG4535	Mg2 and Co2 transporter CorC
YZOS03_RS12125	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YZOS03_RS12130	COG2888	peptidyl-tyrosine sulfation
YZOS03_RS12135	COG0495	leucyl-tRNA aminoacylation
YZOS03_RS12140	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
YZOS03_RS12145	COG1466	dna polymerase III delta subunit
YZOS03_RS12150	COG0799	negative regulation of ribosome biogenesis
YZOS03_RS12155	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
YZOS03_RS12160	COG0768	penicillin binding
YZOS03_RS12165	COG0772	Belongs to the SEDS family
YZOS03_RS12170	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YZOS03_RS12175	COG1686	Belongs to the peptidase S11 family
YZOS03_RS12185	COG0321	lipoyl(octanoyl) transferase activity
YZOS03_RS12190	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
YZOS03_RS12195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
YZOS03_RS12200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
YZOS03_RS12215	COG0366	Alpha amylase catalytic
YZOS03_RS12220	COG1263	PTS System
YZOS03_RS12220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YZOS03_RS12230	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YZOS03_RS12235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YZOS03_RS12240	COG2011	ABC-type metal ion transport system permease component
YZOS03_RS12245	COG1464	Belongs to the NlpA lipoprotein family
YZOS03_RS12250	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
YZOS03_RS12260	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YZOS03_RS12260	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YZOS03_RS12275	COG1611	Belongs to the LOG family
YZOS03_RS12280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YZOS03_RS12290	COG2363	Small membrane protein
YZOS03_RS12300	COG0583	DNA-binding transcription factor activity
YZOS03_RS12305	COG0301	tRNA thio-modification
YZOS03_RS12305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YZOS03_RS12315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YZOS03_RS12320	COG1722	exodeoxyribonuclease VII activity
YZOS03_RS12325	COG0142	geranyltranstransferase activity
YZOS03_RS12330	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
YZOS03_RS12335	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YZOS03_RS12340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YZOS03_RS12350	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
YZOS03_RS12365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YZOS03_RS12365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YZOS03_RS12370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
YZOS03_RS12375	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
YZOS03_RS12380	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
YZOS03_RS12390	COG1073	alpha beta
YZOS03_RS12395	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
YZOS03_RS12400	COG2252	PERMEase
YZOS03_RS12405	COG2195	Cleaves the N-terminal amino acid of tripeptides
YZOS03_RS12420	COG1629	transport
YZOS03_RS12430	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
YZOS03_RS12430	COG0047	phosphoribosylformylglycinamidine synthase activity
YZOS03_RS12435	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
YZOS03_RS12445	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
YZOS03_RS12475	COG0484	heat shock protein binding
YZOS03_RS12485	COG1301	dicarboxylic acid transport
YZOS03_RS12490	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
YZOS03_RS12495	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YZOS03_RS12505	COG0497	DNA recombination
YZOS03_RS12515	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YZOS03_RS12520	COG2914	Belongs to the UPF0125 (RnfH) family
YZOS03_RS12525	COG2867	negative regulation of translational initiation
YZOS03_RS12530	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
YZOS03_RS12550	COG2189	Belongs to the N(4) N(6)-methyltransferase family
YZOS03_RS12565	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YZOS03_RS12580	COG0328	RNA-DNA hybrid ribonuclease activity
YZOS03_RS12585	COG2003	Belongs to the UPF0758 family
YZOS03_RS12640	COG0583	DNA-binding transcription factor activity
YZOS03_RS12645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YZOS03_RS12645	COG3153	acetyltransferase
YZOS03_RS12665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
YZOS03_RS12670	COG2873	o-acetylhomoserine
YZOS03_RS12685	COG1115	amino acid carrier protein
YZOS03_RS12690	COG1584	GPR1 FUN34 yaaH family protein
YZOS03_RS12700	COG1757	Na H antiporter
YZOS03_RS12705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
YZOS03_RS12705	COG0519	Catalyzes the synthesis of GMP from XMP
YZOS03_RS12710	COG0516	GMP reductase activity
YZOS03_RS12710	COG0517	IMP dehydrogenase activity
YZOS03_RS12730	COG1160	GTP binding
YZOS03_RS12735	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YZOS03_RS12740	COG2976	Protein conserved in bacteria
YZOS03_RS12745	COG0124	histidyl-tRNA synthetase
YZOS03_RS12750	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
YZOS03_RS12765	COG0105	UTP biosynthetic process
YZOS03_RS12775	COG2975	iron-sulfur cluster assembly
YZOS03_RS12780	COG0633	Ferredoxin
YZOS03_RS12785	COG0443	Heat shock 70 kDa protein
YZOS03_RS12800	COG0822	iron-sulfur transferase activity
YZOS03_RS12805	COG1104	cysteine desulfurase activity
YZOS03_RS12815	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
YZOS03_RS12820	COG0483	inositol monophosphate 1-phosphatase activity
YZOS03_RS12825	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YZOS03_RS12830	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YZOS03_RS12835	COG1862	Preprotein translocase
YZOS03_RS12845	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
YZOS03_RS12855	COG0517	IMP dehydrogenase activity
YZOS03_RS12865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YZOS03_RS12870	COG0583	DNA-binding transcription factor activity
YZOS03_RS12875	COG0450	alkyl hydroperoxide reductase
YZOS03_RS12880	COG3142	Participates in the control of copper homeostasis
YZOS03_RS12890	COG0704	Plays a role in the regulation of phosphate uptake
YZOS03_RS12895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
YZOS03_RS12900	COG0581	inorganic phosphate transmembrane transporter activity
YZOS03_RS12905	COG0573	inorganic phosphate transmembrane transporter activity
YZOS03_RS12910	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YZOS03_RS12915	COG0248	Ppx GppA phosphatase
YZOS03_RS12925	COG5002	protein histidine kinase activity
YZOS03_RS12935	COG2974	May be involved in recombination
YZOS03_RS12940	COG0826	peptidase U32
YZOS03_RS12945	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YZOS03_RS13000	COG0542	response to heat
YZOS03_RS13010	COG0564	pseudouridine synthase activity
YZOS03_RS13015	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YZOS03_RS13025	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YZOS03_RS13030	COG0077	Prephenate dehydratase
YZOS03_RS13030	COG1605	Chorismate mutase
YZOS03_RS13035	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
YZOS03_RS13040	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YZOS03_RS13050	COG0488	(ABC) transporter
YZOS03_RS13060	COG0739	heme binding
YZOS03_RS13065	COG0287	Prephenate dehydrogenase
YZOS03_RS13065	COG1605	Chorismate mutase
YZOS03_RS13070	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YZOS03_RS13075	COG1472	Belongs to the glycosyl hydrolase 3 family
YZOS03_RS13080	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
YZOS03_RS13100	COG1966	Carbon starvation protein
YZOS03_RS13105	COG3275	phosphorelay sensor kinase activity
YZOS03_RS13110	COG3279	Response regulator of the LytR AlgR family
YZOS03_RS13120	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
YZOS03_RS13125	COG1047	Peptidyl-prolyl cis-trans
YZOS03_RS13140	COG0196	riboflavin kinase activity
YZOS03_RS13145	COG0728	peptidoglycan biosynthetic process
YZOS03_RS13150	COG0268	Binds directly to 16S ribosomal RNA
YZOS03_RS13155	COG0640	Transcriptional regulator
YZOS03_RS13160	COG0583	DNA-binding transcription factor activity
YZOS03_RS13165	COG1283	sodium-dependent phosphate transmembrane transporter activity
YZOS03_RS13175	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
YZOS03_RS13180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
YZOS03_RS13185	COG0730	response to heat
YZOS03_RS13210	COG0667	Aldo Keto reductase
YZOS03_RS13220	COG2204	response regulator
YZOS03_RS13235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YZOS03_RS13240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YZOS03_RS13245	COG4974	Belongs to the 'phage' integrase family
YZOS03_RS13250	COG0716	FMN binding
YZOS03_RS13260	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
YZOS03_RS13265	COG0513	Belongs to the DEAD box helicase family
YZOS03_RS13270	COG3022	response to hydroperoxide
YZOS03_RS13275	COG1115	amino acid carrier protein
YZOS03_RS13290	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YZOS03_RS13295	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
YZOS03_RS13300	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
YZOS03_RS13310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
YZOS03_RS13315	COG0083	homoserine kinase activity
YZOS03_RS13335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YZOS03_RS13345	COG0745	RESPONSE REGULATOR receiver
YZOS03_RS13360	COG2203	Gaf domain
YZOS03_RS13360	COG3706	GGDEF domain
YZOS03_RS13360	COG4251	negative regulation of phosphorylation
YZOS03_RS13360	COG5001	Diguanylate cyclase
YZOS03_RS13365	COG1242	4 iron, 4 sulfur cluster binding
YZOS03_RS13370	COG0069	glutamate synthase activity
YZOS03_RS13370	COG0070	glutamate synthase
YZOS03_RS13370	COG0067	glutamate synthase
YZOS03_RS13380	COG0069	glutamate synthase activity
YZOS03_RS13380	COG0070	glutamate synthase
YZOS03_RS13380	COG0067	glutamate synthase
YZOS03_RS13385	COG0493	'glutamate synthase
YZOS03_RS13395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YZOS03_RS13410	COG2860	membrane
YZOS03_RS13415	COG0583	DNA-binding transcription factor activity
YZOS03_RS13420	COG0730	response to heat
YZOS03_RS13435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YZOS03_RS13440	COG0505	Belongs to the CarA family
YZOS03_RS13450	COG0494	nUDIX hydrolase
YZOS03_RS13455	COG0653	protein targeting
YZOS03_RS13465	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
YZOS03_RS13470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YZOS03_RS13475	COG0849	cell division
YZOS03_RS13480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YZOS03_RS13495	COG0772	Belongs to the SEDS family
YZOS03_RS13500	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
YZOS03_RS13505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YZOS03_RS13510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YZOS03_RS13515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YZOS03_RS13525	COG3116	cell division
YZOS03_RS13540	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YZOS03_RS13555	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
YZOS03_RS13560	COG2823	Periplasmic or secreted lipoprotein
YZOS03_RS13565	COG2969	positive regulation of protein catabolic process
YZOS03_RS13570	COG0625	glutathione transferase activity
YZOS03_RS13575	COG2857	Cytochrome c1
YZOS03_RS13580	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
YZOS03_RS13585	COG0723	plastoquinol--plastocyanin reductase activity
YZOS03_RS13590	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
YZOS03_RS13600	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YZOS03_RS13605	COG3105	Protein conserved in bacteria
YZOS03_RS13615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YZOS03_RS13620	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YZOS03_RS13630	COG3150	esterase
YZOS03_RS13640	COG3151	Protein conserved in bacteria
YZOS03_RS13645	COG0494	nUDIX hydrolase
YZOS03_RS13650	COG1538	Outer membrane efflux protein
YZOS03_RS13655	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
YZOS03_RS13655	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
YZOS03_RS13675	COG3025	triphosphatase activity
YZOS03_RS13680	COG1392	Phosphate transport regulator
YZOS03_RS13685	COG0306	phosphate transporter
YZOS03_RS13690	COG4991	sh3 domain protein
YZOS03_RS13695	COG0405	Gamma-glutamyltransferase
YZOS03_RS13705	COG3409	Peptidoglycan-binding domain 1 protein
YZOS03_RS13705	COG3267	Type II secretory pathway component ExeA
YZOS03_RS13715	COG1968	undecaprenyl-diphosphatase activity
YZOS03_RS13720	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YZOS03_RS13725	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YZOS03_RS13730	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
YZOS03_RS13735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
YZOS03_RS13740	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
YZOS03_RS13745	COG0828	Belongs to the bacterial ribosomal protein bS21 family
YZOS03_RS13750	COG1610	YqeY-like protein
YZOS03_RS13755	COG0358	DNA primase activity
YZOS03_RS13790	COG2213	PTS system mannitol-specific
YZOS03_RS13790	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YZOS03_RS13800	COG3722	fumarate hydratase activity
YZOS03_RS13815	COG1461	Dihydroxyacetone kinase
YZOS03_RS13820	COG1461	Dihydroxyacetone kinase
YZOS03_RS13825	COG2376	Dihydroxyacetone kinase
YZOS03_RS13835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
YZOS03_RS13840	COG1349	DNA-binding transcription factor activity
YZOS03_RS13845	COG0469	pyruvate kinase activity
YZOS03_RS13860	COG0440	acetolactate synthase activity
YZOS03_RS13865	COG0028	Belongs to the TPP enzyme family
YZOS03_RS13870	COG1022	Amp-dependent synthetase and ligase
YZOS03_RS13875	COG0583	DNA-binding transcription factor activity
YZOS03_RS13895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YZOS03_RS13900	COG0473	3-isopropylmalate dehydrogenase activity
YZOS03_RS13920	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YZOS03_RS13925	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YZOS03_RS13930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YZOS03_RS13935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
YZOS03_RS13940	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
YZOS03_RS13945	COG2967	ApaG domain
YZOS03_RS13950	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YZOS03_RS13965	COG2966	Psort location CytoplasmicMembrane, score
YZOS03_RS13970	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
YZOS03_RS13980	COG0261	This protein binds to 23S rRNA in the presence of protein L20
YZOS03_RS13985	COG0142	geranyltranstransferase activity
YZOS03_RS14005	COG2358	TRAP transporter, solute receptor (TAXI family
YZOS03_RS14020	COG1902	pentaerythritol trinitrate reductase activity
YZOS03_RS14025	COG0583	DNA-binding transcription factor activity
YZOS03_RS14030	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
YZOS03_RS14035	COG1178	ABC-type Fe3 transport system permease component
YZOS03_RS14040	COG4143	(ABC) transporter
YZOS03_RS14045	COG0163	prenyltransferase activity
YZOS03_RS14050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YZOS03_RS14055	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
YZOS03_RS14060	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YZOS03_RS14070	COG2105	PFAM AIG2 family protein
YZOS03_RS14075	COG2911	Protein conserved in bacteria
YZOS03_RS14080	COG0729	surface antigen
YZOS03_RS14095	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YZOS03_RS14110	COG4181	ATPase activity
YZOS03_RS14130	COG0529	Catalyzes the synthesis of activated sulfate
YZOS03_RS14135	COG3273	potassium ion transport
YZOS03_RS14135	COG0471	metal ion transport
YZOS03_RS14140	COG2895	sulfate adenylyltransferase (ATP) activity
YZOS03_RS14145	COG0175	sulfate reduction
YZOS03_RS14150	COG1648	precorrin-2 dehydrogenase activity
YZOS03_RS14150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YZOS03_RS14165	COG0513	Belongs to the DEAD box helicase family
YZOS03_RS14170	COG2153	protein acetylation
YZOS03_RS14180	COG0545	Peptidyl-prolyl cis-trans isomerase
YZOS03_RS14190	COG0203	ribosomal protein L17
YZOS03_RS14195	COG0202	RNA polymerase activity
YZOS03_RS14205	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
YZOS03_RS14210	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
YZOS03_RS14215	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YZOS03_RS14220	COG0201	protein transport
YZOS03_RS14225	COG0200	Binds to the 23S rRNA
YZOS03_RS14230	COG1841	ribosomal large subunit assembly
YZOS03_RS14245	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
YZOS03_RS14250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YZOS03_RS14260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
YZOS03_RS14265	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
YZOS03_RS14275	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YZOS03_RS14280	COG0255	Belongs to the universal ribosomal protein uL29 family
YZOS03_RS14290	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YZOS03_RS14295	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
YZOS03_RS14300	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YZOS03_RS14305	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
YZOS03_RS14315	COG0088	Forms part of the polypeptide exit tunnel
YZOS03_RS14320	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
YZOS03_RS14330	COG0254	rRNA binding
YZOS03_RS14335	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YZOS03_RS14340	COG1609	Transcriptional regulator
YZOS03_RS14350	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
YZOS03_RS14355	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
YZOS03_RS14360	COG1575	Belongs to the MenA family. Type 1 subfamily
YZOS03_RS14365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YZOS03_RS14375	COG1494	fructose-1,6-bisphosphatase
YZOS03_RS14405	COG0149	triose-phosphate isomerase activity
YZOS03_RS14455	COG1216	Glycosyl transferase, family 2
YZOS03_RS14470	COG0812	UDP-N-acetylmuramate dehydrogenase activity
YZOS03_RS14480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YZOS03_RS14485	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
YZOS03_RS14490	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
YZOS03_RS14495	COG1215	transferase activity, transferring glycosyl groups
YZOS03_RS14500	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YZOS03_RS14500	COG2755	lipolytic protein G-D-S-L family
YZOS03_RS14545	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YZOS03_RS14585	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YZOS03_RS14595	COG1560	Kdo2-lipid A biosynthetic process
YZOS03_RS14610	COG0859	PFAM glycosyl transferase family 9
YZOS03_RS14615	COG1519	Transferase
YZOS03_RS14620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YZOS03_RS14660	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YZOS03_RS14670	COG3642	lipopolysaccharide core region biosynthetic process
YZOS03_RS14675	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YZOS03_RS14680	COG0859	PFAM glycosyl transferase family 9
YZOS03_RS14685	COG0463	Glycosyl transferase, family 2
YZOS03_RS14700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
YZOS03_RS14725	COG2003	Belongs to the UPF0758 family
YZOS03_RS14735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YZOS03_RS14740	COG1309	transcriptional regulator
YZOS03_RS14745	COG1560	Kdo2-lipid A biosynthetic process
YZOS03_RS14750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
YZOS03_RS14755	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
YZOS03_RS14770	COG4608	Belongs to the ABC transporter superfamily
YZOS03_RS14775	COG0444	Belongs to the ABC transporter superfamily
YZOS03_RS14780	COG0747	negative chemotaxis
YZOS03_RS14785	COG4239	(ABC) transporter, permease
YZOS03_RS14790	COG4174	ABC transporter (Permease)
YZOS03_RS14810	COG0811	peptide transport
YZOS03_RS14815	COG0848	biopolymer transport protein
YZOS03_RS14830	COG0194	GDP metabolic process
YZOS03_RS14835	COG1758	RNA polymerase activity
YZOS03_RS14840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YZOS03_RS14845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YZOS03_RS14850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YZOS03_RS14855	COG2233	PERMEase
YZOS03_RS14875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YZOS03_RS14885	COG2183	response to ionizing radiation
YZOS03_RS14900	COG1040	competence protein
YZOS03_RS14910	COG0494	nUDIX hydrolase
YZOS03_RS14915	COG1218	3'(2'),5'-bisphosphate nucleotidase
YZOS03_RS14925	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
YZOS03_RS14930	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
YZOS03_RS14935	COG3156	type II secretion system protein K
YZOS03_RS14940	COG4795	General secretion pathway protein
YZOS03_RS14945	COG2165	general secretion pathway protein
YZOS03_RS14950	COG2165	general secretion pathway protein
YZOS03_RS14955	COG2165	general secretion pathway protein
YZOS03_RS14960	COG1459	type II secretion system
YZOS03_RS14965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YZOS03_RS14975	COG3031	protein transport across the cell outer membrane
YZOS03_RS14980	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YZOS03_RS14985	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
YZOS03_RS14990	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
YZOS03_RS15000	COG0456	acetyltransferase
YZOS03_RS15005	COG1490	D-aminoacyl-tRNA deacylase activity
YZOS03_RS15010	COG1295	ribonuclease BN
YZOS03_RS15020	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
YZOS03_RS15025	COG1217	gtp-binding protein TYPA
YZOS03_RS15030	COG0174	glutamine synthetase
YZOS03_RS15040	COG3852	Histidine kinase
YZOS03_RS15045	COG2204	response regulator
YZOS03_RS15055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
YZOS03_RS15085	COG0218	Necessary for normal cell division and for the maintenance of normal septation
YZOS03_RS15090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YZOS03_RS15090	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YZOS03_RS15095	COG0456	acetyltransferase
YZOS03_RS15105	COG0084	hydrolase, TatD family'
YZOS03_RS15115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YZOS03_RS15125	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
YZOS03_RS15130	COG3165	ubiquinone biosynthetic process from chorismate
YZOS03_RS15135	COG2226	methyltransferase
YZOS03_RS15140	COG1322	Protein conserved in bacteria
YZOS03_RS15155	COG0628	permease
YZOS03_RS15185	COG1597	lipid kinase activity
YZOS03_RS15215	COG2081	HI0933 family
YZOS03_RS15225	COG1528	Iron-storage protein
YZOS03_RS15230	COG0589	response to stress
YZOS03_RS15245	COG0742	ribosomal rna small subunit methyltransferase
YZOS03_RS15250	COG5001	Diguanylate cyclase
YZOS03_RS15250	COG5002	protein histidine kinase activity
YZOS03_RS15255	COG1522	sequence-specific DNA binding
YZOS03_RS15265	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YZOS03_RS15270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YZOS03_RS15275	COG0583	DNA-binding transcription factor activity
YZOS03_RS15280	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
YZOS03_RS15285	COG0800	Aldolase
YZOS03_RS15290	COG2610	gluconate transmembrane transporter activity
YZOS03_RS15295	COG3265	gluconokinase activity
YZOS03_RS15300	COG0129	dihydroxy-acid dehydratase activity
YZOS03_RS15315	COG0583	DNA-binding transcription factor activity
YZOS03_RS15320	COG1609	Transcriptional regulator
YZOS03_RS15330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YZOS03_RS15335	COG0601	transmembrane transport
YZOS03_RS15340	COG4166	transmembrane transport
YZOS03_RS15395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YZOS03_RS15400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YZOS03_RS15405	COG2960	long-chain fatty acid transporting porin activity
YZOS03_RS15410	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
YZOS03_RS15415	COG0583	DNA-binding transcription factor activity
YZOS03_RS15450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YZOS03_RS15470	COG0009	L-threonylcarbamoyladenylate synthase
YZOS03_RS15475	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YZOS03_RS15480	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YZOS03_RS15485	COG0551	DNA topoisomerase type I activity
YZOS03_RS15490	COG2922	Belongs to the Smg family
YZOS03_RS15495	COG0758	DNA mediated transformation
YZOS03_RS15505	COG0242	peptide deformylase activity
YZOS03_RS15510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YZOS03_RS15515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
YZOS03_RS15515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YZOS03_RS15520	COG0569	domain protein
YZOS03_RS15535	COG1272	protein, Hemolysin III
YZOS03_RS15540	COG4326	sporulation control protein
YZOS03_RS15550	COG3084	Protein conserved in bacteria
YZOS03_RS15560	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YZOS03_RS15565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YZOS03_RS15570	COG0204	Acyl-transferase
YZOS03_RS15590	COG3978	acetolactate synthase activity
YZOS03_RS15595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YZOS03_RS15600	COG0129	dihydroxy-acid dehydratase activity
YZOS03_RS15610	COG0583	DNA-binding transcription factor activity
YZOS03_RS15615	COG2814	Major facilitator Superfamily
YZOS03_RS15625	COG0765	amino acid transport
YZOS03_RS15635	COG0355	proton-transporting ATP synthase activity, rotational mechanism
YZOS03_RS15640	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
YZOS03_RS15645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
YZOS03_RS15650	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
YZOS03_RS15655	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
YZOS03_RS15660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
YZOS03_RS15670	COG0356	it plays a direct role in the translocation of protons across the membrane
YZOS03_RS15675	COG3312	ion transport
YZOS03_RS15680	COG1475	DNA binding
YZOS03_RS15685	COG1192	Involved in chromosome partitioning
YZOS03_RS15690	COG0357	Ribosomal RNA small subunit methyltransferase G
YZOS03_RS15695	COG0445	tRNA wobble uridine modification
YZOS03_RS15700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YZOS03_RS15710	COG0706	membrane insertase activity
YZOS03_RS15720	COG0594	ribonuclease P activity
YZOS03_RS15730	COG1126	abc transporter atp-binding protein
YZOS03_RS15785	COG0803	Belongs to the bacterial solute-binding protein 9 family
YZOS03_RS15790	COG1121	(ABC) transporter
YZOS03_RS15795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YZOS03_RS15810	COG1770	oligopeptidase
YZOS03_RS15815	COG2814	Major facilitator Superfamily
YZOS03_RS15820	COG0010	Belongs to the arginase family
YZOS03_RS15825	COG1166	arginine decarboxylase activity
YZOS03_RS15835	COG4067	protein conserved in archaea
YZOS03_RS15835	COG0189	ligase activity
YZOS03_RS15840	COG0189	ligase activity
YZOS03_RS15860	COG0583	DNA-binding transcription factor activity
YZOS03_RS15890	COG3706	GGDEF domain
YZOS03_RS15910	COG0579	oxidoreductase
YZOS03_RS15920	COG1294	oxidase, subunit
YZOS03_RS15925	COG1271	oxidase subunit
YZOS03_RS15935	COG3033	Beta-eliminating lyase
YZOS03_RS15950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YZOS03_RS15965	COG3706	GGDEF domain
YZOS03_RS15980	COG3706	GGDEF domain
YZOS03_RS15985	COG0415	Belongs to the DNA photolyase family
YZOS03_RS15990	COG3046	protein related to deoxyribodipyrimidine photolyase
YZOS03_RS16005	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YZOS03_RS16005	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YZOS03_RS16010	COG1765	OsmC-like protein
YZOS03_RS16015	COG0110	maltose O-acetyltransferase activity
YZOS03_RS16055	COG1011	Hydrolase
YZOS03_RS16080	COG2067	long-chain fatty acid transport protein
YZOS03_RS16085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YZOS03_RS16090	COG0577	efflux transmembrane transporter activity
YZOS03_RS16090	COG1136	(ABC) transporter
YZOS03_RS16105	COG1309	transcriptional regulator
YZOS03_RS16110	COG3240	lipase activity
YZOS03_RS16130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YZOS03_RS16140	COG1840	ABC-type Fe3 transport system, periplasmic component
YZOS03_RS16145	COG3842	ATPase activity
YZOS03_RS16170	COG2990	Protein conserved in bacteria
YZOS03_RS16180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YZOS03_RS16185	COG2866	Carboxypeptidase
YZOS03_RS16195	COG0583	DNA-binding transcription factor activity
YZOS03_RS16210	COG1760	l-serine dehydratase
YZOS03_RS16230	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
YZOS03_RS16235	COG1388	LysM domain
YZOS03_RS16235	COG0741	lytic transglycosylase activity
YZOS03_RS16255	COG1815	bacterial-type flagellum-dependent cell motility
YZOS03_RS16260	COG1558	bacterial-type flagellum-dependent cell motility
YZOS03_RS16275	COG4787	bacterial-type flagellum-dependent cell motility
YZOS03_RS16280	COG4786	Flagellar basal body rod
YZOS03_RS16285	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
YZOS03_RS16300	COG1256	bacterial-type flagellum assembly
YZOS03_RS16300	COG4786	Flagellar basal body rod
YZOS03_RS16325	COG1304	FMN binding
YZOS03_RS16340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YZOS03_RS16345	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
YZOS03_RS16350	COG0459	protein refolding
YZOS03_RS16360	COG1280	lysine exporter protein (LysE YggA)
YZOS03_RS16380	COG1309	transcriptional regulator
YZOS03_RS16390	COG4303	Ethanolamine ammonia lyase large subunit
YZOS03_RS16395	COG4302	ethanolamine ammonia-lyase activity
YZOS03_RS16400	COG0531	amino acid
YZOS03_RS16410	COG2070	2-Nitropropane dioxygenase
YZOS03_RS16420	COG1349	DNA-binding transcription factor activity
YZOS03_RS16435	COG1335	isochorismatase
YZOS03_RS16445	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
YZOS03_RS16470	COG0583	DNA-binding transcription factor activity
YZOS03_RS16485	COG3713	MltA-interacting MipA family protein
YZOS03_RS16490	COG3015	lipoprotein NlpE involved in copper resistance
YZOS03_RS16495	COG3448	diguanylate cyclase activity
YZOS03_RS16495	COG4175	Glycine betaine
YZOS03_RS16500	COG4176	ABC-type proline glycine betaine transport system permease component
YZOS03_RS16505	COG1342	Belongs to the UPF0251 family
YZOS03_RS16535	COG4948	Mandelate Racemase Muconate Lactonizing
YZOS03_RS16545	COG0583	DNA-binding transcription factor activity
YZOS03_RS16580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YZOS03_RS16630	COG3842	ATPase activity
YZOS03_RS16660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YZOS03_RS16685	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
YZOS03_RS16690	COG2197	response regulator
YZOS03_RS16705	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
YZOS03_RS16710	COG0252	asparaginase activity
YZOS03_RS16715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
YZOS03_RS16720	COG0583	DNA-binding transcription factor activity
YZOS03_RS16735	COG3122	Protein conserved in bacteria
YZOS03_RS16740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
YZOS03_RS16745	COG1012	belongs to the aldehyde dehydrogenase family
YZOS03_RS16750	COG1522	sequence-specific DNA binding
YZOS03_RS16755	COG3608	succinylglutamate desuccinylase aspartoacylase
YZOS03_RS16760	COG0006	proline dipeptidase activity
YZOS03_RS16765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YZOS03_RS16775	COG1028	Short-chain dehydrogenase reductase Sdr
YZOS03_RS16785	COG1063	alcohol dehydrogenase
YZOS03_RS16790	COG1902	pentaerythritol trinitrate reductase activity
YZOS03_RS16805	COG0583	DNA-binding transcription factor activity
YZOS03_RS16815	COG0513	Belongs to the DEAD box helicase family
YZOS03_RS16835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YZOS03_RS16840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YZOS03_RS16840	COG2207	Transcriptional regulator
YZOS03_RS16845	COG0583	DNA-binding transcription factor activity
YZOS03_RS16850	COG0300	oxidoreductase activity
YZOS03_RS16865	COG3746	phosphate-selective porin O and P
YZOS03_RS16880	COG1028	Short-chain dehydrogenase reductase Sdr
YZOS03_RS16900	COG1263	PTS System
YZOS03_RS16900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YZOS03_RS16905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YZOS03_RS16910	COG1621	beta-fructofuranosidase activity
YZOS03_RS16915	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YZOS03_RS16925	COG0625	glutathione transferase activity
YZOS03_RS16930	COG1686	Belongs to the peptidase S11 family
YZOS03_RS16940	COG0678	peroxiredoxin activity
YZOS03_RS16940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YZOS03_RS16945	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
YZOS03_RS16960	COG1278	Cold shock
YZOS03_RS16965	COG1741	Belongs to the pirin family
YZOS03_RS16970	COG4667	esterase of the alpha-beta hydrolase superfamily
YZOS03_RS16990	COG2194	sulfuric ester hydrolase activity
YZOS03_RS16995	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YZOS03_RS17005	COG2205	protein histidine kinase activity
YZOS03_RS17010	COG0745	RESPONSE REGULATOR receiver
YZOS03_RS17025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YZOS03_RS17045	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YZOS03_RS17055	COG2814	Major facilitator Superfamily
YZOS03_RS17065	COG1418	mRNA catabolic process
YZOS03_RS17070	COG0402	S-adenosylhomocysteine deaminase activity
YZOS03_RS17075	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
YZOS03_RS17085	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
YZOS03_RS17090	COG1566	PFAM secretion protein HlyD family protein
YZOS03_RS17115	COG0745	RESPONSE REGULATOR receiver
YZOS03_RS17120	COG2205	protein histidine kinase activity
YZOS03_RS17135	COG0531	amino acid
YZOS03_RS17145	COG0583	DNA-binding transcription factor activity
YZOS03_RS17170	COG2205	protein histidine kinase activity
YZOS03_RS17170	COG0784	Response regulator, receiver
YZOS03_RS17170	COG5002	protein histidine kinase activity
YZOS03_RS17190	COG3132	Protein of unknown function, DUF480
YZOS03_RS17195	COG2827	Endonuclease containing a URI domain
YZOS03_RS17200	COG1879	ABC-type sugar transport system periplasmic component
YZOS03_RS17205	COG0784	Response regulator, receiver
YZOS03_RS17205	COG2205	protein histidine kinase activity
YZOS03_RS17210	COG1846	Transcriptional regulator
YZOS03_RS17265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YZOS03_RS17275	COG1280	lysine exporter protein (LysE YggA)
YZOS03_RS17285	COG0183	Belongs to the thiolase family
YZOS03_RS17295	COG3243	poly(R)-hydroxyalkanoic acid synthase
YZOS03_RS17305	COG3005	denitrification pathway
YZOS03_RS17315	COG0243	molybdopterin cofactor binding
YZOS03_RS17325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YZOS03_RS17330	COG3850	Histidine kinase
YZOS03_RS17335	COG2197	response regulator
YZOS03_RS17350	COG2195	Cleaves the N-terminal amino acid of tripeptides
YZOS03_RS17370	COG0840	transmembrane signaling receptor activity
YZOS03_RS17380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YZOS03_RS17390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YZOS03_RS17395	COG2814	Major facilitator Superfamily
YZOS03_RS17405	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YZOS03_RS17410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YZOS03_RS17420	COG2897	thiosulfate sulfurtransferase activity
YZOS03_RS17455	COG0038	chloride channel
YZOS03_RS17470	COG4989	oxidoreductase activity
YZOS03_RS17485	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YZOS03_RS17485	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YZOS03_RS17495	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
YZOS03_RS17540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YZOS03_RS17565	COG0739	heme binding
YZOS03_RS17610	COG3501	Rhs element vgr protein
YZOS03_RS17635	COG0515	serine threonine protein kinase
YZOS03_RS17670	COG1522	sequence-specific DNA binding
YZOS03_RS17740	COG2814	Major facilitator Superfamily
YZOS03_RS17750	COG0583	DNA-binding transcription factor activity
YZOS03_RS17755	COG4221	oxidoreductase activity
YZOS03_RS17760	COG0589	response to stress
YZOS03_RS17770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YZOS03_RS17770	COG2111	Na H antiporter
YZOS03_RS17775	COG1006	Multisubunit Na H antiporter MnhC subunit
YZOS03_RS17780	COG0651	ATP synthesis coupled electron transport
YZOS03_RS17785	COG1863	multisubunit Na H antiporter MnhE subunit
YZOS03_RS17790	COG2212	antiporter activity
YZOS03_RS17795	COG1320	monovalent cation:proton antiporter activity
YZOS03_RS17800	COG2188	Transcriptional regulator
YZOS03_RS17805	COG1486	melibiose metabolic process
YZOS03_RS17810	COG1263	PTS System
YZOS03_RS17810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YZOS03_RS17815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YZOS03_RS17840	COG1022	Amp-dependent synthetase and ligase
YZOS03_RS17870	COG0500	methyltransferase
YZOS03_RS17890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YZOS03_RS17895	COG1028	Short-chain dehydrogenase reductase Sdr
YZOS03_RS17905	COG3527	Alpha-acetolactate decarboxylase
YZOS03_RS17920	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
YZOS03_RS17935	COG0384	phenazine biosynthesis protein PhzF
YZOS03_RS17945	COG1294	oxidase, subunit
YZOS03_RS17950	COG1271	oxidase subunit
YZOS03_RS17955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YZOS03_RS17960	COG0110	maltose O-acetyltransferase activity
YZOS03_RS17965	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
YZOS03_RS17965	COG3264	Mechanosensitive ion channel
YZOS03_RS17980	COG4770	biotin carboxylase activity
YZOS03_RS17990	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
YZOS03_RS17995	COG1960	acyl-CoA dehydrogenase activity
YZOS03_RS18005	COG0183	Belongs to the thiolase family
YZOS03_RS18015	COG1960	acyl-CoA dehydrogenase activity
YZOS03_RS18020	COG1024	Enoyl-CoA hydratase
YZOS03_RS18035	COG1028	Short-chain dehydrogenase reductase Sdr
YZOS03_RS18045	COG1309	transcriptional regulator
YZOS03_RS18050	COG1012	belongs to the aldehyde dehydrogenase family
YZOS03_RS18065	COG4176	ABC-type proline glycine betaine transport system permease component
YZOS03_RS18070	COG0517	IMP dehydrogenase activity
YZOS03_RS18070	COG4175	Glycine betaine
YZOS03_RS18085	COG0330	HflC and HflK could
YZOS03_RS18100	COG2205	protein histidine kinase activity
YZOS03_RS18100	COG0784	Response regulator, receiver
YZOS03_RS18165	COG5001	Diguanylate cyclase
YZOS03_RS18170	COG1869	D-ribose catabolic process
YZOS03_RS18175	COG1129	ABC transporter
YZOS03_RS18180	COG1172	Belongs to the binding-protein-dependent transport system permease family
YZOS03_RS18185	COG1879	ABC-type sugar transport system periplasmic component
YZOS03_RS18190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YZOS03_RS18195	COG1609	Transcriptional regulator
YZOS03_RS18205	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
YZOS03_RS18215	COG4607	ABC-type enterochelin transport system periplasmic component
YZOS03_RS18220	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YZOS03_RS18225	COG4605	iron ion homeostasis
YZOS03_RS18230	COG4604	ABC transporter, ATP-binding protein
YZOS03_RS18235	COG0789	Transcriptional regulator
YZOS03_RS18245	COG1629	transport
YZOS03_RS18245	COG4771	TonB-dependent receptor
YZOS03_RS18275	COG1289	transmembrane transporter activity
YZOS03_RS18280	COG0210	DNA helicase
YZOS03_RS18285	COG1803	Methylglyoxal synthase
YZOS03_RS18290	COG1879	ABC-type sugar transport system periplasmic component
YZOS03_RS18295	COG2205	protein histidine kinase activity
YZOS03_RS18295	COG2198	Histidine kinase
YZOS03_RS18295	COG0784	Response regulator, receiver
YZOS03_RS18310	COG0745	RESPONSE REGULATOR receiver
YZOS03_RS18315	COG3119	arylsulfatase activity
YZOS03_RS18325	COG3119	arylsulfatase activity
YZOS03_RS18330	COG0641	radical SAM
YZOS03_RS18335	COG0714	Associated with various cellular activities
YZOS03_RS18365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YZOS03_RS18370	COG0583	DNA-binding transcription factor activity
YZOS03_RS18375	COG1597	lipid kinase activity
YZOS03_RS18380	COG3111	PFAM Bacterial OB fold (BOF) protein
YZOS03_RS18405	COG3069	C4-dicarboxylate transmembrane transporter activity
YZOS03_RS18415	COG0456	acetyltransferase
YZOS03_RS18415	COG1214	PFAM Peptidase M22, glycoprotease
YZOS03_RS18435	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
YZOS03_RS18440	COG2205	protein histidine kinase activity
YZOS03_RS18440	COG0784	Response regulator, receiver
YZOS03_RS18445	COG5001	Diguanylate cyclase
YZOS03_RS18445	COG3300	MHYT domain
YZOS03_RS18450	COG2197	response regulator
YZOS03_RS18455	COG3706	GGDEF domain
YZOS03_RS18465	COG2197	response regulator
YZOS03_RS18470	COG0835	chemotaxis
YZOS03_RS18470	COG0784	Response regulator, receiver
YZOS03_RS18485	COG2962	Rard protein
YZOS03_RS18505	COG2076	Multidrug Resistance protein
YZOS03_RS18540	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
YZOS03_RS18545	COG5642	Protein of unknown function (DUF2384)
YZOS03_RS18555	COG2755	lipolytic protein G-D-S-L family
YZOS03_RS18555	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YZOS03_RS18565	COG1902	pentaerythritol trinitrate reductase activity
YZOS03_RS18570	COG0346	lactoylglutathione lyase activity
YZOS03_RS18590	COG2239	Acts as a magnesium transporter
YZOS03_RS18615	COG0242	peptide deformylase activity
YZOS03_RS18655	COG2176	DNA-directed DNA polymerase activity
YZOS03_RS18705	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YZOS03_RS18710	COG0697	spore germination
YZOS03_RS18720	COG0583	DNA-binding transcription factor activity
YZOS03_RS18725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YZOS03_RS18730	COG0346	lactoylglutathione lyase activity
YZOS03_RS18740	COG0509	glycine decarboxylation via glycine cleavage system
YZOS03_RS18745	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
YZOS03_RS18755	COG0404	The glycine cleavage system catalyzes the degradation of glycine
YZOS03_RS18785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YZOS03_RS18785	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YZOS03_RS18785	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YZOS03_RS18790	COG1105	Belongs to the carbohydrate kinase PfkB family
YZOS03_RS18795	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YZOS03_RS18795	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YZOS03_RS18800	COG1609	Transcriptional regulator
YZOS03_RS18815	COG2200	EAL domain
YZOS03_RS18815	COG2203	Gaf domain
YZOS03_RS18815	COG2199	diguanylate cyclase activity
YZOS03_RS18820	COG0765	amino acid transport
YZOS03_RS18825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YZOS03_RS18830	COG0765	amino acid transport
YZOS03_RS18835	COG1126	abc transporter atp-binding protein
YZOS03_RS18845	COG1979	alcohol dehydrogenase
YZOS03_RS18850	COG2207	Transcriptional regulator
YZOS03_RS18860	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
YZOS03_RS18865	COG2759	Belongs to the formate--tetrahydrofolate ligase family
YZOS03_RS18870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YZOS03_RS18885	COG0546	phosphoglycolate phosphatase activity
YZOS03_RS18890	COG0840	transmembrane signaling receptor activity
YZOS03_RS18900	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
YZOS03_RS18905	COG0513	Belongs to the DEAD box helicase family
YZOS03_RS18925	COG3038	cytochrome b561
YZOS03_RS18930	COG2353	YceI-like domain
YZOS03_RS18935	COG2116	formate transmembrane transporter activity
YZOS03_RS18940	COG0583	DNA-binding transcription factor activity
YZOS03_RS18950	COG3593	DNA synthesis involved in DNA repair
YZOS03_RS18955	COG0737	Belongs to the 5'-nucleotidase family
YZOS03_RS18980	COG2267	carboxylic ester hydrolase activity
YZOS03_RS18985	COG2067	long-chain fatty acid transport protein
YZOS03_RS19000	COG2050	protein possibly involved in aromatic compounds catabolism
YZOS03_RS19010	COG4533	DNA binding
YZOS03_RS19045	COG5001	Diguanylate cyclase
YZOS03_RS19045	COG3300	MHYT domain
YZOS03_RS19050	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
YZOS03_RS19060	COG4181	ATPase activity
YZOS03_RS19065	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YZOS03_RS19075	COG1984	allophanate hydrolase subunit 2
YZOS03_RS19080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
YZOS03_RS19085	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
YZOS03_RS19105	COG0583	DNA-binding transcription factor activity
YZOS03_RS19110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YZOS03_RS19110	COG0045	succinate-CoA ligase (ADP-forming) activity
YZOS03_RS19110	COG1042	CoA-binding domain protein
YZOS03_RS19120	COG1181	Belongs to the D-alanine--D-alanine ligase family
YZOS03_RS19130	COG0023	Translation Initiation Factor
YZOS03_RS19260	COG4128	Pfam Zonular occludens toxin
YZOS03_RS19275	COG0393	Putative heavy-metal-binding
YZOS03_RS19310	COG0583	DNA-binding transcription factor activity
YZOS03_RS19325	COG3140	Belongs to the UPF0181 family
YZOS03_RS19350	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YZOS03_RS19355	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YZOS03_RS19375	COG2203	Gaf domain
YZOS03_RS19375	COG3706	GGDEF domain
YZOS03_RS19375	COG5001	Diguanylate cyclase
YZOS03_RS19375	COG4251	negative regulation of phosphorylation
YZOS03_RS19385	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
YZOS03_RS19390	COG4149	molybdate abc transporter
YZOS03_RS19395	COG0725	ABC transporter, periplasmic molybdate-binding protein
YZOS03_RS19405	COG3111	PFAM Bacterial OB fold (BOF) protein
YZOS03_RS19415	COG0189	ligase activity
YZOS03_RS19415	COG4067	protein conserved in archaea
YZOS03_RS19425	COG2207	Transcriptional regulator
YZOS03_RS19430	COG0534	Mate efflux family protein
YZOS03_RS19435	COG0602	queuosine metabolic process
YZOS03_RS19440	COG1328	CTP reductase activity
YZOS03_RS19470	COG1794	racemase activity, acting on amino acids and derivatives
YZOS03_RS19475	COG0384	phenazine biosynthesis protein PhzF
YZOS03_RS19490	COG0243	molybdopterin cofactor binding
YZOS03_RS19495	COG0583	DNA-binding transcription factor activity
YZOS03_RS19500	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
YZOS03_RS19510	COG2197	response regulator
YZOS03_RS19515	COG3851	Histidine kinase
YZOS03_RS19520	COG2271	Major facilitator Superfamily
YZOS03_RS19545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YZOS03_RS19550	COG3118	belongs to the thioredoxin family
YZOS03_RS19585	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YZOS03_RS19605	COG2116	formate transmembrane transporter activity
YZOS03_RS19620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YZOS03_RS19640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YZOS03_RS19690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YZOS03_RS19705	COG0277	FAD linked oxidase domain protein
YZOS03_RS19710	COG0583	DNA-binding transcription factor activity
YZOS03_RS19725	COG2425	protein containing a von Willebrand factor type A (vWA) domain
YZOS03_RS19740	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YZOS03_RS19750	COG1288	antiporter activity
YZOS03_RS19760	COG3040	lipid binding
YZOS03_RS19770	COG0419	ATPase involved in DNA repair
YZOS03_RS19775	COG0420	3'-5' exonuclease activity
YZOS03_RS19845	COG0631	protein serine/threonine phosphatase activity
YZOS03_RS19880	COG0515	serine threonine protein kinase
YZOS03_RS19880	COG2815	serine threonine protein kinase
YZOS03_RS19930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YZOS03_RS19930	COG2146	nitrite reductase [NAD(P)H] activity
YZOS03_RS19935	COG1116	anion transmembrane transporter activity
YZOS03_RS19940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YZOS03_RS19945	COG1116	anion transmembrane transporter activity
YZOS03_RS19945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YZOS03_RS19960	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YZOS03_RS19970	COG0243	molybdopterin cofactor binding
YZOS03_RS19980	COG0814	amino acid
YZOS03_RS20040	COG2847	Copper chaperone PCu(A)C
YZOS03_RS20045	COG1028	Short-chain dehydrogenase reductase Sdr
YZOS03_RS20050	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
YZOS03_RS20060	COG0800	Aldolase
YZOS03_RS20065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YZOS03_RS20070	COG1917	Cupin 2, conserved barrel domain protein
YZOS03_RS20115	COG2186	Transcriptional regulator
YZOS03_RS20120	COG2186	Transcriptional regulator
YZOS03_RS20125	COG0517	IMP dehydrogenase activity
YZOS03_RS20130	COG2176	DNA-directed DNA polymerase activity
YZOS03_RS20135	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YZOS03_RS20205	COG4160	amino acid transport
YZOS03_RS20210	COG4215	(ABC) transporter
YZOS03_RS20215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YZOS03_RS20220	COG1126	abc transporter atp-binding protein
YZOS03_RS20250	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YZOS03_RS20260	COG1012	belongs to the aldehyde dehydrogenase family
YZOS03_RS20275	COG0446	pyridine nucleotide-disulphide oxidoreductase
YZOS03_RS20275	COG1902	pentaerythritol trinitrate reductase activity
YZOS03_RS20280	COG0109	protoheme IX farnesyltransferase activity
YZOS03_RS20285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YZOS03_RS20290	COG1845	cytochrome c oxidase, subunit III
YZOS03_RS20295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YZOS03_RS20300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YZOS03_RS20305	COG1028	Short-chain dehydrogenase reductase Sdr
YZOS03_RS20315	COG1024	Enoyl-CoA hydratase
YZOS03_RS20320	COG1024	Enoyl-CoA hydratase
YZOS03_RS20335	COG0183	Belongs to the thiolase family
YZOS03_RS20350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
YZOS03_RS20355	COG1024	Enoyl-CoA hydratase
YZOS03_RS20430	COG2095	MarC family integral membrane protein
YZOS03_RS20445	COG0523	cobalamin synthesis protein
YZOS03_RS20450	COG0739	heme binding
YZOS03_RS20455	COG2988	succinylglutamate desuccinylase activity
YZOS03_RS20460	COG0523	cobalamin synthesis protein
YZOS03_RS20470	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
YZOS03_RS20475	COG0735	belongs to the Fur family
YZOS03_RS20490	COG0730	response to heat
YZOS03_RS20510	COG1073	alpha beta
YZOS03_RS20515	COG1073	alpha beta
YZOS03_RS20525	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
YZOS03_RS20540	COG0513	Belongs to the DEAD box helicase family
YZOS03_RS20545	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
YZOS03_RS20580	COG1119	ATPase activity
YZOS03_RS20585	COG2200	EAL domain
YZOS03_RS20605	COG0513	Belongs to the DEAD box helicase family
YZOS03_RS20610	COG0523	cobalamin synthesis protein
YZOS03_RS20620	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
YZOS03_RS20630	COG1278	Cold shock
YZOS03_RS20640	COG0133	tryptophan synthase activity
YZOS03_RS20650	COG4628	conserved protein (DUF2132)
YZOS03_RS20655	COG0513	Belongs to the DEAD box helicase family
YZOS03_RS20680	COG3530	Putative quorum-sensing-regulated virulence factor
YZOS03_RS20705	COG3186	Phenylalanine-4-hydroxylase
YZOS03_RS20710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YZOS03_RS20715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YZOS03_RS20740	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YZOS03_RS20745	COG1454	alcohol dehydrogenase
YZOS03_RS20750	COG2133	pyrroloquinoline quinone binding
YZOS03_RS20760	COG0783	Belongs to the Dps family
YZOS03_RS20765	COG0840	transmembrane signaling receptor activity
YZOS03_RS20790	COG2205	protein histidine kinase activity
YZOS03_RS20790	COG0784	Response regulator, receiver
YZOS03_RS20795	COG1538	Outer membrane efflux protein
YZOS03_RS20805	COG1132	(ABC) transporter
YZOS03_RS20820	COG2199	diguanylate cyclase activity
YZOS03_RS20825	COG3036	rescue of stalled ribosome
YZOS03_RS20830	COG1278	Cold shock
YZOS03_RS20860	COG0545	Peptidyl-prolyl cis-trans isomerase
YZOS03_RS20865	COG0109	protoheme IX farnesyltransferase activity
YZOS03_RS20870	COG1612	heme a metabolic process
YZOS03_RS20890	COG1845	cytochrome c oxidase, subunit III
YZOS03_RS20895	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
YZOS03_RS20900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YZOS03_RS20905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YZOS03_RS20910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YZOS03_RS20920	COG1280	lysine exporter protein (LysE YggA)
YZOS03_RS20940	COG0179	Fumarylacetoacetate (FAA) hydrolase
YZOS03_RS20955	COG0697	spore germination
YZOS03_RS20970	COG2814	Major facilitator Superfamily
YZOS03_RS20975	COG0583	DNA-binding transcription factor activity
YZOS03_RS20980	COG5001	Diguanylate cyclase
YZOS03_RS20985	COG0739	heme binding
YZOS03_RS21005	COG3314	Sporulation integral membrane protein YlbJ
YZOS03_RS21020	COG0814	amino acid
YZOS03_RS21045	COG4989	oxidoreductase activity
YZOS03_RS21070	COG1733	regulation of RNA biosynthetic process
YZOS03_RS21085	COG0798	PFAM Bile acid sodium symporter
YZOS03_RS21110	COG1131	(ABC) transporter
YZOS03_RS21115	COG0842	Transport permease protein
YZOS03_RS21125	COG3383	formate dehydrogenase (NAD+) activity
YZOS03_RS21145	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YZOS03_RS21170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YZOS03_RS21180	COG2067	long-chain fatty acid transport protein
YZOS03_RS21190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YZOS03_RS21200	COG1505	serine-type exopeptidase activity
YZOS03_RS21205	COG0488	(ABC) transporter
YZOS03_RS21210	COG0589	response to stress
YZOS03_RS21215	COG2249	NAD(P)H dehydrogenase (quinone) activity
YZOS03_RS21235	COG0366	Alpha amylase catalytic
YZOS03_RS21240	COG0789	Transcriptional regulator
YZOS03_RS21245	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YZOS03_RS21255	COG4934	collagen metabolic process
YZOS03_RS21265	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
YZOS03_RS21270	COG0583	DNA-binding transcription factor activity
YZOS03_RS21290	COG2610	gluconate transmembrane transporter activity
YZOS03_RS21295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YZOS03_RS21300	COG3622	Belongs to the hyi family
YZOS03_RS21305	COG0235	Class ii aldolase
YZOS03_RS21310	COG3395	kinase activity
YZOS03_RS21315	COG2084	Dehydrogenase
YZOS03_RS21320	COG1349	DNA-binding transcription factor activity
YZOS03_RS21330	COG0747	negative chemotaxis
YZOS03_RS21335	COG4608	Belongs to the ABC transporter superfamily
YZOS03_RS21340	COG0444	Belongs to the ABC transporter superfamily
YZOS03_RS21345	COG0534	Mate efflux family protein
YZOS03_RS21350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YZOS03_RS21355	COG0784	Response regulator, receiver
YZOS03_RS21355	COG0835	chemotaxis
YZOS03_RS21365	COG0748	coenzyme F420 binding
YZOS03_RS21370	COG3721	Heme iron utilization protein
YZOS03_RS21380	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YZOS03_RS21385	COG0811	peptide transport
YZOS03_RS21390	COG0848	biopolymer transport protein
YZOS03_RS21400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YZOS03_RS21405	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YZOS03_RS21445	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
YZOS03_RS21455	COG0633	Ferredoxin
YZOS03_RS21455	COG3217	Mosc domain protein beta barrel domain protein
YZOS03_RS21455	COG0633	Ferredoxin
YZOS03_RS21455	COG3217	Mosc domain protein beta barrel domain protein
YZOS03_RS21460	COG0401	homolog of Blt101
YZOS03_RS21465	COG0418	dihydroorotase activity
YZOS03_RS21470	COG2354	Protein conserved in bacteria
YZOS03_RS21500	COG3833	ABC-type maltose transport systems, permease component
YZOS03_RS21505	COG1175	transmembrane transport
YZOS03_RS21515	COG3842	ATPase activity
YZOS03_RS21520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
YZOS03_RS21575	COG3097	Belongs to the UPF0267 family
YZOS03_RS21580	COG1309	transcriptional regulator
YZOS03_RS21585	COG2130	NADP-dependent
YZOS03_RS21595	COG0753	catalase activity
YZOS03_RS21600	COG2084	Dehydrogenase
YZOS03_RS21630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YZOS03_RS21635	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
YZOS03_RS21645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YZOS03_RS21650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YZOS03_RS21660	COG1012	belongs to the aldehyde dehydrogenase family
YZOS03_RS21675	COG0583	DNA-binding transcription factor activity
YZOS03_RS21680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YZOS03_RS21685	COG0569	domain protein
YZOS03_RS21690	COG0745	RESPONSE REGULATOR receiver
YZOS03_RS21695	COG2205	protein histidine kinase activity
YZOS03_RS21695	COG2205	protein histidine kinase activity
YZOS03_RS21700	COG1132	(ABC) transporter
YZOS03_RS21705	COG4774	siderophore transport
YZOS03_RS21710	COG1120	ATPase activity
YZOS03_RS21715	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
YZOS03_RS21750	COG2197	response regulator
YZOS03_RS21765	COG0714	Associated with various cellular activities
YZOS03_RS21780	COG2304	oxidoreductase activity
YZOS03_RS21800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
YZOS03_RS21805	COG0581	inorganic phosphate transmembrane transporter activity
YZOS03_RS21810	COG0573	inorganic phosphate transmembrane transporter activity
YZOS03_RS21840	COG4771	TonB-dependent receptor
YZOS03_RS21845	COG1770	oligopeptidase
YZOS03_RS21850	COG0513	Belongs to the DEAD box helicase family
YZOS03_RS21860	COG1388	LysM domain
YZOS03_RS21860	COG1376	ErfK ybiS ycfS ynhG family protein
YZOS03_RS21865	COG0415	Belongs to the DNA photolyase family
YZOS03_RS21870	COG0789	Transcriptional regulator
YZOS03_RS21875	COG3272	Protein of unknown function (DUF1722)
YZOS03_RS21880	COG0813	purine-nucleoside phosphorylase activity
YZOS03_RS21905	COG1566	PFAM secretion protein HlyD family protein
YZOS03_RS21910	COG4720	Psort location CytoplasmicMembrane, score
YZOS03_RS21915	COG1122	ATPase activity
YZOS03_RS21935	COG0348	domain, Protein
YZOS03_RS21940	COG0437	4 iron, 4 sulfur cluster binding
YZOS03_RS21945	COG1247	-acetyltransferase
YZOS03_RS21965	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YZOS03_RS21985	COG4172	Belongs to the ABC transporter superfamily
YZOS03_RS21990	COG1505	serine-type exopeptidase activity
YZOS03_RS21995	COG0583	DNA-binding transcription factor activity
YZOS03_RS22000	COG1620	l-lactate permease
YZOS03_RS22005	COG1304	FMN binding
YZOS03_RS22015	COG0668	transmembrane transport
YZOS03_RS22050	COG1063	alcohol dehydrogenase
YZOS03_RS22055	COG0156	8-amino-7-oxononanoate synthase activity
YZOS03_RS22060	COG3300	MHYT domain
YZOS03_RS22060	COG5001	Diguanylate cyclase
YZOS03_RS22085	COG0745	RESPONSE REGULATOR receiver
YZOS03_RS22110	COG0346	lactoylglutathione lyase activity
YZOS03_RS22170	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
YZOS03_RS22210	COG1987	bacterial-type flagellum assembly
YZOS03_RS22220	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YZOS03_RS22235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YZOS03_RS22245	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
YZOS03_RS22250	COG1516	flagellar protein fliS
YZOS03_RS22265	COG1580	Controls the rotational direction of flagella during chemotaxis
YZOS03_RS22270	COG1191	sigma factor activity
YZOS03_RS22275	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YZOS03_RS22280	COG1360	Flagellar Motor Protein
YZOS03_RS22315	COG1882	Formate acetyltransferase
YZOS03_RS22320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YZOS03_RS22340	COG2205	protein histidine kinase activity
YZOS03_RS22345	COG0745	RESPONSE REGULATOR receiver
YZOS03_RS22355	COG0454	-acetyltransferase
YZOS03_RS22365	COG2814	Major facilitator Superfamily
YZOS03_RS22405	COG0628	permease
YZOS03_RS22410	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
YZOS03_RS22430	COG4628	conserved protein (DUF2132)
YZOS03_RS22435	COG0583	DNA-binding transcription factor activity
YZOS03_RS22460	COG1686	Belongs to the peptidase S11 family
YZOS03_RS22470	COG1054	Belongs to the UPF0176 family
YZOS03_RS22480	COG0415	Belongs to the DNA photolyase family
YZOS03_RS22485	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
YZOS03_RS22490	COG3397	chitin binding
YZOS03_RS22495	COG4667	esterase of the alpha-beta hydrolase superfamily
YZOS03_RS22500	COG2095	MarC family integral membrane protein
YZOS03_RS22520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
YZOS03_RS22540	COG0583	DNA-binding transcription factor activity
YZOS03_RS22550	COG1301	dicarboxylic acid transport
YZOS03_RS22555	COG3339	Conserved Protein
YZOS03_RS22560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YZOS03_RS22565	COG0700	Nucleoside recognition
YZOS03_RS22570	COG3366	ferrous iron transmembrane transporter activity
YZOS03_RS22585	COG0366	Alpha amylase catalytic
YZOS03_RS22590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YZOS03_RS22595	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
YZOS03_RS22600	COG1640	4-alpha-glucanotransferase
YZOS03_RS22605	COG0058	SHG alpha-glucan phosphorylase activity
YZOS03_RS22610	COG2909	trisaccharide binding
YZOS03_RS22625	COG1999	signal sequence binding
YZOS03_RS22630	COG1263	PTS System
YZOS03_RS22630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YZOS03_RS22635	COG1162	GTPase activity
YZOS03_RS22640	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
YZOS03_RS22645	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
YZOS03_RS22655	COG0531	amino acid
YZOS03_RS22660	COG1982	Orn Lys Arg decarboxylase major
YZOS03_RS22680	COG2356	endonuclease I
YZOS03_RS22700	COG4580	involved in the transport of maltose and maltodextrins
YZOS03_RS22750	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YZOS03_RS22760	COG1609	Transcriptional regulator
YZOS03_RS22765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YZOS03_RS22775	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
YZOS03_RS22775	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
YZOS03_RS22790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YZOS03_RS22795	COG1609	Transcriptional regulator
YZOS03_RS22805	COG2814	Major facilitator Superfamily
YZOS03_RS22820	COG0739	heme binding
YZOS03_RS22830	COG0612	Peptidase, M16
YZOS03_RS22835	COG0840	transmembrane signaling receptor activity
YZOS03_RS22840	COG1120	ATPase activity
YZOS03_RS22845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YZOS03_RS22850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YZOS03_RS22855	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
YZOS03_RS22860	COG4772	TonB-dependent receptor
YZOS03_RS22880	COG2814	Major facilitator Superfamily
YZOS03_RS22885	COG4264	IucA IucC family
YZOS03_RS22890	COG0019	diaminopimelate decarboxylase activity
YZOS03_RS22920	COG0826	peptidase U32
YZOS03_RS22930	COG1136	(ABC) transporter
YZOS03_RS22935	COG0577	efflux transmembrane transporter activity
YZOS03_RS22970	COG1764	response to oxidative stress
YZOS03_RS22975	COG1846	Transcriptional regulator
YZOS03_RS22985	COG3634	alkyl hydroperoxide reductase activity
YZOS03_RS23035	COG2258	MOSC domain
YZOS03_RS23040	COG0513	Belongs to the DEAD box helicase family
YZOS03_RS23050	COG1132	(ABC) transporter
YZOS03_RS23115	COG0259	pyridoxamine-phosphate oxidase activity
YZOS03_RS23160	COG4166	transmembrane transport
YZOS03_RS23175	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
YZOS03_RS23180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YZOS03_RS23180	COG1263	PTS System
YZOS03_RS23185	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YZOS03_RS23190	COG3340	Belongs to the peptidase S51 family
YZOS03_RS23210	COG1444	tRNA N-acetyltransferase activity
YZOS03_RS23235	COG4608	Belongs to the ABC transporter superfamily
YZOS03_RS23240	COG0444	Belongs to the ABC transporter superfamily
YZOS03_RS23250	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YZOS03_RS23250	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
YZOS03_RS23275	COG0772	Belongs to the SEDS family
YZOS03_RS23285	COG1136	(ABC) transporter
YZOS03_RS23305	COG3275	phosphorelay sensor kinase activity
YZOS03_RS23310	COG3279	Response regulator of the LytR AlgR family
YZOS03_RS23315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YZOS03_RS23335	COG0786	glutamate:sodium symporter activity
YZOS03_RS23345	COG1131	(ABC) transporter
YZOS03_RS23350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YZOS03_RS23355	COG0786	glutamate:sodium symporter activity
YZOS03_RS23365	COG0363	glucosamine-6-phosphate deaminase activity
YZOS03_RS23385	COG1741	Belongs to the pirin family
YZOS03_RS23390	COG2259	Doxx family
YZOS03_RS23400	COG2169	Transcriptional regulator
YZOS03_RS23400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YZOS03_RS23405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YZOS03_RS23415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
YZOS03_RS23440	COG0596	Alpha beta hydrolase
YZOS03_RS23455	COG3123	guanosine phosphorylase activity
YZOS03_RS23470	COG0534	Mate efflux family protein
YZOS03_RS23475	COG0564	pseudouridine synthase activity
YZOS03_RS23490	COG0583	DNA-binding transcription factor activity
YZOS03_RS23495	COG0561	phosphatase activity
YZOS03_RS23505	COG2199	diguanylate cyclase activity
YZOS03_RS23520	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
YZOS03_RS23525	COG2162	N-hydroxyarylamine O-acetyltransferase activity
YZOS03_RS23530	COG0583	DNA-binding transcription factor activity
YZOS03_RS23535	COG2375	cellular response to nickel ion
YZOS03_RS23565	COG1357	PFAM Pentapeptide repeats (8 copies)
YZOS03_RS23570	COG3047	cAMP biosynthetic process
YZOS03_RS23630	COG3835	regulator
YZOS03_RS23635	COG2610	gluconate transmembrane transporter activity
YZOS03_RS23640	COG1929	Belongs to the glycerate kinase type-1 family
YZOS03_RS23645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YZOS03_RS23665	COG0456	acetyltransferase
YZOS03_RS23680	COG1028	Short-chain dehydrogenase reductase Sdr
YZOS03_RS23685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YZOS03_RS23695	COG0243	molybdopterin cofactor binding
YZOS03_RS23715	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
YZOS03_RS23720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YZOS03_RS23725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YZOS03_RS23730	COG1116	anion transmembrane transporter activity
YZOS03_RS23735	COG0351	phosphomethylpyrimidine kinase
YZOS03_RS23745	COG0312	modulator of DNA gyrase
YZOS03_RS23750	COG1901	pseudouridine methyltransferase
YZOS03_RS23810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YZOS03_RS23820	COG0584	glycerophosphoryl diester phosphodiesterase
YZOS03_RS23825	COG0745	RESPONSE REGULATOR receiver
YZOS03_RS23845	COG0811	peptide transport
YZOS03_RS23850	COG0811	peptide transport
YZOS03_RS23855	COG0848	biopolymer transport protein