locus-tag	class	description
CLI14_RS00005	COG0445	tRNA wobble uridine modification
CLI14_RS00015	COG1192	Involved in chromosome partitioning
CLI14_RS00020	COG1475	DNA binding
CLI14_RS00025	COG3312	ion transport
CLI14_RS00040	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CLI14_RS00045	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLI14_RS00050	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CLI14_RS00055	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CLI14_RS00060	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CLI14_RS00065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CLI14_RS00075	COG2814	Major facilitator Superfamily
CLI14_RS00080	COG0583	DNA-binding transcription factor activity
CLI14_RS00085	COG0183	Belongs to the thiolase family
CLI14_RS00095	COG1739	Uncharacterized protein family UPF0029
CLI14_RS00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CLI14_RS00105	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CLI14_RS00155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CLI14_RS00160	COG0352	thiamine-phosphate diphosphorylase activity
CLI14_RS00170	COG2104	thiamine diphosphate biosynthetic process
CLI14_RS00175	COG2022	thiamine diphosphate biosynthetic process
CLI14_RS00180	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CLI14_RS00185	COG0006	proline dipeptidase activity
CLI14_RS00185	COG0006	proline dipeptidase activity
CLI14_RS00210	COG1522	sequence-specific DNA binding
CLI14_RS00215	COG0742	ribosomal rna small subunit methyltransferase
CLI14_RS00230	COG0589	response to stress
CLI14_RS00235	COG1528	Iron-storage protein
CLI14_RS00250	COG2081	HI0933 family
CLI14_RS00260	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLI14_RS00265	COG1129	ABC transporter
CLI14_RS00270	COG1879	ABC-type sugar transport system periplasmic component
CLI14_RS00275	COG1069	ribulokinase activity
CLI14_RS00285	COG2160	L-arabinose isomerase activity
CLI14_RS00305	COG1322	Protein conserved in bacteria
CLI14_RS00310	COG2226	methyltransferase
CLI14_RS00320	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CLI14_RS00325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLI14_RS00330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLI14_RS00335	COG0805	protein transport
CLI14_RS00345	COG0084	hydrolase, TatD family'
CLI14_RS00355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLI14_RS00355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLI14_RS00375	COG3078	GTPase activator activity
CLI14_RS00395	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CLI14_RS00400	COG2960	long-chain fatty acid transporting porin activity
CLI14_RS00405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLI14_RS00410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLI14_RS00415	COG1309	transcriptional regulator
CLI14_RS00465	COG0601	transmembrane transport
CLI14_RS00470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLI14_RS00525	COG2433	Pfam Transposase IS66
CLI14_RS00545	COG3081	Nucleoid-associated protein
CLI14_RS00565	COG2433	Pfam Transposase IS66
CLI14_RS00575	COG5290	Psort location Cytoplasmic, score
CLI14_RS00620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLI14_RS00625	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CLI14_RS00630	COG0339	signal peptide processing
CLI14_RS00635	COG0210	DNA helicase
CLI14_RS00640	COG1280	lysine exporter protein (LysE YggA)
CLI14_RS00650	COG2962	Rard protein
CLI14_RS00655	COG0514	ATP-dependent DNA helicase (RecQ)
CLI14_RS00675	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CLI14_RS00680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI14_RS00680	COG1263	PTS System
CLI14_RS00685	COG1132	(ABC) transporter
CLI14_RS00690	COG4774	siderophore transport
CLI14_RS00695	COG1120	ATPase activity
CLI14_RS00720	COG0612	Peptidase, M16
CLI14_RS00760	COG1061	Type III restriction enzyme res subunit
CLI14_RS00795	COG1396	sequence-specific DNA binding
CLI14_RS00810	COG1561	YicC-like family, N-terminal region
CLI14_RS00815	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CLI14_RS00820	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CLI14_RS00825	COG1560	Kdo2-lipid A biosynthetic process
CLI14_RS00830	COG1560	Kdo2-lipid A biosynthetic process
CLI14_RS00835	COG1309	transcriptional regulator
CLI14_RS00840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLI14_RS00845	COG2003	Belongs to the UPF0758 family
CLI14_RS00850	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CLI14_RS00855	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CLI14_RS00865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CLI14_RS00870	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CLI14_RS00875	COG0859	PFAM glycosyl transferase family 9
CLI14_RS00880	COG0463	Glycosyl transferase, family 2
CLI14_RS00885	COG0859	PFAM glycosyl transferase family 9
CLI14_RS00890	COG3642	lipopolysaccharide core region biosynthetic process
CLI14_RS00905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLI14_RS00915	COG1519	Transferase
CLI14_RS00930	COG0859	PFAM glycosyl transferase family 9
CLI14_RS00935	COG3307	-O-antigen
CLI14_RS00945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLI14_RS00970	COG1682	transport, permease protein
CLI14_RS01025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLI14_RS01035	COG0463	Glycosyl transferase, family 2
CLI14_RS01065	COG3754	Rhamnan synthesis protein F
CLI14_RS01090	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CLI14_RS01100	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLI14_RS01120	COG1596	polysaccharide export
CLI14_RS01125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLI14_RS01160	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLI14_RS01165	COG0438	transferase activity, transferring glycosyl groups
CLI14_RS01180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLI14_RS01185	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CLI14_RS01195	COG0668	transmembrane transport
CLI14_RS01200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLI14_RS01205	COG3068	Protein conserved in bacteria
CLI14_RS01210	COG2852	Protein conserved in bacteria
CLI14_RS01215	COG1253	flavin adenine dinucleotide binding
CLI14_RS01220	COG0776	regulation of translation
CLI14_RS01230	COG0151	Belongs to the GarS family
CLI14_RS01235	COG0138	bifunctional purine biosynthesis protein purh
CLI14_RS01240	COG0789	Transcriptional regulator
CLI14_RS01250	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CLI14_RS01255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLI14_RS01260	COG2264	protein methyltransferase activity
CLI14_RS01265	COG0439	Biotin carboxylase
CLI14_RS01270	COG0511	ligase activity, forming carbon-carbon bonds
CLI14_RS01275	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CLI14_RS01280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLI14_RS01295	COG2814	Major facilitator Superfamily
CLI14_RS01300	COG2205	protein histidine kinase activity
CLI14_RS01300	COG2198	Histidine kinase
CLI14_RS01300	COG0784	Response regulator, receiver
CLI14_RS01305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLI14_RS01325	COG4232	protein-disulfide reductase activity
CLI14_RS01330	COG1438	arginine binding
CLI14_RS01335	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CLI14_RS01340	COG0540	Belongs to the ATCase OTCase family
CLI14_RS01350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CLI14_RS01355	COG0549	Belongs to the carbamate kinase family
CLI14_RS01365	COG1288	antiporter activity
CLI14_RS01375	COG1027	Aspartate ammonia-lyase
CLI14_RS01380	COG3030	protein affecting phage T7 exclusion by the F plasmid
CLI14_RS01385	COG1278	Cold shock
CLI14_RS01390	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CLI14_RS01395	COG2205	protein histidine kinase activity
CLI14_RS01400	COG0745	RESPONSE REGULATOR receiver
CLI14_RS01410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLI14_RS01415	COG0205	6-phosphofructokinase activity
CLI14_RS01420	COG1494	fructose-1,6-bisphosphatase
CLI14_RS01425	COG3074	FtsZ-dependent cytokinesis
CLI14_RS01430	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CLI14_RS01435	COG0460	homoserine dehydrogenase
CLI14_RS01435	COG0527	aspartate kinase activity
CLI14_RS01440	COG0626	cystathionine gamma-synthase activity
CLI14_RS01450	COG0281	malic enzyme
CLI14_RS01460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLI14_RS01465	COG1609	Transcriptional regulator
CLI14_RS01475	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CLI14_RS01480	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CLI14_RS01485	COG1575	Belongs to the MenA family. Type 1 subfamily
CLI14_RS01490	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLI14_RS01495	COG0534	Mate efflux family protein
CLI14_RS01525	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CLI14_RS01530	COG0459	protein refolding
CLI14_RS01545	COG1509	lysine 2,3-aminomutase activity
CLI14_RS01550	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLI14_RS01560	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CLI14_RS01565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CLI14_RS01570	COG1053	succinate dehydrogenase
CLI14_RS01575	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CLI14_RS01580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLI14_RS01590	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CLI14_RS01595	COG1045	serine acetyltransferase
CLI14_RS01605	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CLI14_RS01610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLI14_RS01615	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CLI14_RS01620	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CLI14_RS01625	COG0137	argininosuccinate synthase activity
CLI14_RS01630	COG0165	Argininosuccinate lyase
CLI14_RS01630	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CLI14_RS01640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLI14_RS01645	COG0678	peroxiredoxin activity
CLI14_RS01645	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CLI14_RS01655	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CLI14_RS01685	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLI14_RS01690	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CLI14_RS01700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CLI14_RS01705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CLI14_RS01710	COG0546	phosphoglycolate phosphatase activity
CLI14_RS01715	COG0180	Tryptophanyl-tRNA synthetase
CLI14_RS01730	COG0583	DNA-binding transcription factor activity
CLI14_RS01740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLI14_RS01755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLI14_RS01765	COG1012	belongs to the aldehyde dehydrogenase family
CLI14_RS01775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLI14_RS01780	COG3954	Phosphoribulokinase
CLI14_RS01790	COG0429	hydrolase of the alpha beta-hydrolase fold
CLI14_RS01800	COG0488	(ABC) transporter
CLI14_RS01805	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLI14_RS01815	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CLI14_RS01820	COG1047	Peptidyl-prolyl cis-trans
CLI14_RS01830	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CLI14_RS01840	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CLI14_RS01845	COG0557	exoribonuclease II activity
CLI14_RS01850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLI14_RS01855	COG0051	transcription antitermination factor activity, RNA binding
CLI14_RS01860	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CLI14_RS01865	COG0088	Forms part of the polypeptide exit tunnel
CLI14_RS01875	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CLI14_RS01880	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLI14_RS01895	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CLI14_RS01905	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CLI14_RS01915	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CLI14_RS01920	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CLI14_RS01925	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CLI14_RS01930	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CLI14_RS01935	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CLI14_RS01945	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CLI14_RS01950	COG1841	ribosomal large subunit assembly
CLI14_RS01955	COG0200	Binds to the 23S rRNA
CLI14_RS01960	COG0201	protein transport
CLI14_RS01965	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CLI14_RS01970	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CLI14_RS01975	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CLI14_RS01980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CLI14_RS01985	COG0202	RNA polymerase activity
CLI14_RS01990	COG0203	ribosomal protein L17
CLI14_RS01995	COG0545	Peptidyl-prolyl cis-trans isomerase
CLI14_RS02000	COG3061	Opacity-associated protein A
CLI14_RS02000	COG3266	domain, Protein
CLI14_RS02005	COG2153	protein acetylation
CLI14_RS02010	COG0513	Belongs to the DEAD box helicase family
CLI14_RS02050	COG0737	Belongs to the 5'-nucleotidase family
CLI14_RS02055	COG1648	precorrin-2 dehydrogenase activity
CLI14_RS02055	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CLI14_RS02060	COG0175	sulfate reduction
CLI14_RS02065	COG2895	sulfate adenylyltransferase (ATP) activity
CLI14_RS02070	COG0529	Catalyzes the synthesis of activated sulfate
CLI14_RS02105	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CLI14_RS02110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLI14_RS02115	COG0729	surface antigen
CLI14_RS02120	COG2911	Protein conserved in bacteria
CLI14_RS02125	COG2105	PFAM AIG2 family protein
CLI14_RS02135	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CLI14_RS02140	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CLI14_RS02145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLI14_RS02150	COG0163	prenyltransferase activity
CLI14_RS02160	COG1178	ABC-type Fe3 transport system permease component
CLI14_RS02165	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CLI14_RS02170	COG3028	Belongs to the UPF0307 family
CLI14_RS02175	COG0312	modulator of DNA gyrase
CLI14_RS02180	COG2239	Acts as a magnesium transporter
CLI14_RS02185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_RS02190	COG1660	Displays ATPase and GTPase activities
CLI14_RS02195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_RS02200	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLI14_RS02210	COG1137	ATPase activity
CLI14_RS02215	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CLI14_RS02225	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CLI14_RS02230	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CLI14_RS02230	COG0517	IMP dehydrogenase activity
CLI14_RS02240	COG1127	ABC transporter
CLI14_RS02245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CLI14_RS02250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CLI14_RS02255	COG2854	intermembrane phospholipid transfer
CLI14_RS02265	COG5007	Belongs to the BolA IbaG family
CLI14_RS02270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLI14_RS02275	COG0204	Acyl-transferase
CLI14_RS02290	COG0251	oxidation-reduction process
CLI14_RS02295	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CLI14_RS02310	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CLI14_RS02320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CLI14_RS02330	COG0564	pseudouridine synthase activity
CLI14_RS02335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLI14_RS02340	COG0525	valine-tRNA ligase activity
CLI14_RS02345	COG2927	DNA polymerase III (CHI subunit)
CLI14_RS02350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CLI14_RS02355	COG0795	lipopolysaccharide-transporting ATPase activity
CLI14_RS02360	COG0795	lipopolysaccharide-transporting ATPase activity
CLI14_RS02445	COG0066	3-isopropylmalate dehydratase activity
CLI14_RS02455	COG0473	3-isopropylmalate dehydrogenase activity
CLI14_RS02475	COG0583	DNA-binding transcription factor activity
CLI14_RS02480	COG1022	Amp-dependent synthetase and ligase
CLI14_RS02485	COG0028	Belongs to the TPP enzyme family
CLI14_RS02495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLI14_RS02505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CLI14_RS02515	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CLI14_RS02520	COG3079	Belongs to the UPF0149 family
CLI14_RS02525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLI14_RS02530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLI14_RS02550	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CLI14_RS02560	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CLI14_RS02565	COG1595	DNA-templated transcription, initiation
CLI14_RS02580	COG3086	response to oxidative stress
CLI14_RS02585	COG0481	GTPase activity
CLI14_RS02595	COG0571	ribonuclease III activity
CLI14_RS02600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CLI14_RS02605	COG1381	Involved in DNA repair and RecF pathway recombination
CLI14_RS02610	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CLI14_RS02615	COG0736	holo-[acyl-carrier-protein] synthase activity
CLI14_RS02620	COG3850	Histidine kinase
CLI14_RS02620	COG3437	response regulator, receiver
CLI14_RS02620	COG2205	protein histidine kinase activity
CLI14_RS02620	COG4999	Histidine kinase
CLI14_RS02625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLI14_RS02630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLI14_RS02635	COG3956	TIGRFAM MazG family protein
CLI14_RS02640	COG0504	CTP synthase activity
CLI14_RS02650	COG0617	tRNA 3'-terminal CCA addition
CLI14_RS02655	COG3409	Peptidoglycan-binding domain 1 protein
CLI14_RS02655	COG3267	Type II secretory pathway component ExeA
CLI14_RS02665	COG4991	sh3 domain protein
CLI14_RS02670	COG0306	phosphate transporter
CLI14_RS02675	COG1392	Phosphate transport regulator
CLI14_RS02680	COG3025	triphosphatase activity
CLI14_RS02695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CLI14_RS02705	COG1538	Outer membrane efflux protein
CLI14_RS02710	COG0494	nUDIX hydrolase
CLI14_RS02715	COG3151	Protein conserved in bacteria
CLI14_RS02725	COG3150	esterase
CLI14_RS02730	COG0187	DNA topoisomerase II activity
CLI14_RS02735	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLI14_RS02740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLI14_RS02745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLI14_RS02750	COG3105	Protein conserved in bacteria
CLI14_RS02755	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CLI14_RS02765	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CLI14_RS02775	COG0723	plastoquinol--plastocyanin reductase activity
CLI14_RS02780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CLI14_RS02785	COG2857	Cytochrome c1
CLI14_RS02790	COG0625	glutathione transferase activity
CLI14_RS02795	COG2969	positive regulation of protein catabolic process
CLI14_RS02805	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CLI14_RS02810	COG0792	nuclease activity
CLI14_RS02815	COG3107	peptidoglycan biosynthetic process
CLI14_RS02820	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CLI14_RS02830	COG0275	rRNA processing
CLI14_RS02835	COG3116	cell division
CLI14_RS02840	COG0768	penicillin binding
CLI14_RS02845	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLI14_RS02850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CLI14_RS02860	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CLI14_RS02865	COG0772	Belongs to the SEDS family
CLI14_RS02870	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLI14_RS02875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLI14_RS02880	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CLI14_RS02885	COG0849	cell division
CLI14_RS02890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLI14_RS02895	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CLI14_RS02905	COG0653	protein targeting
CLI14_RS02910	COG0494	nUDIX hydrolase
CLI14_RS02915	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CLI14_RS02920	COG0505	Belongs to the CarA family
CLI14_RS02925	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CLI14_RS02930	COG0730	response to heat
CLI14_RS02935	COG0583	DNA-binding transcription factor activity
CLI14_RS02940	COG2860	membrane
CLI14_RS02945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLI14_RS02955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CLI14_RS02970	COG0493	'glutamate synthase
CLI14_RS02975	COG0070	glutamate synthase
CLI14_RS02975	COG0069	glutamate synthase activity
CLI14_RS02975	COG0067	glutamate synthase
CLI14_RS02985	COG0069	glutamate synthase activity
CLI14_RS02985	COG0070	glutamate synthase
CLI14_RS02985	COG0067	glutamate synthase
CLI14_RS02990	COG1242	4 iron, 4 sulfur cluster binding
CLI14_RS02995	COG0784	Response regulator, receiver
CLI14_RS02995	COG2198	Histidine kinase
CLI14_RS02995	COG5002	protein histidine kinase activity
CLI14_RS03005	COG0745	RESPONSE REGULATOR receiver
CLI14_RS03010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLI14_RS03025	COG0083	homoserine kinase activity
CLI14_RS03030	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CLI14_RS03035	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CLI14_RS03040	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CLI14_RS03045	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CLI14_RS03060	COG1115	amino acid carrier protein
CLI14_RS03065	COG3022	response to hydroperoxide
CLI14_RS03070	COG0084	hydrolase, TatD family'
CLI14_RS03075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLI14_RS03080	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CLI14_RS03085	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CLI14_RS03090	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CLI14_RS03095	COG0813	purine-nucleoside phosphorylase activity
CLI14_RS03105	COG0560	Phosphoserine phosphatase
CLI14_RS03115	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CLI14_RS03120	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLI14_RS03125	COG4628	conserved protein (DUF2132)
CLI14_RS03130	COG1022	Amp-dependent synthetase and ligase
CLI14_RS03135	COG3437	response regulator, receiver
CLI14_RS03135	COG0784	Response regulator, receiver
CLI14_RS03150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLI14_RS03155	COG1085	galactose-1-phosphate uridylyltransferase
CLI14_RS03165	COG1609	Transcriptional regulator
CLI14_RS03195	COG2171	N-acyltransferase activity
CLI14_RS03200	COG3141	response to X-ray
CLI14_RS03215	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CLI14_RS03220	COG1074	ATP-dependent DNA helicase activity
CLI14_RS03225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CLI14_RS03235	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CLI14_RS03235	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CLI14_RS03245	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CLI14_RS03250	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CLI14_RS03255	COG2166	iron-sulfur cluster assembly
CLI14_RS03260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLI14_RS03270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLI14_RS03285	COG1595	DNA-templated transcription, initiation
CLI14_RS03295	COG2211	Major facilitator Superfamily
CLI14_RS03315	COG0271	Belongs to the BolA IbaG family
CLI14_RS03350	COG1477	protein flavinylation
CLI14_RS03360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLI14_RS03375	COG0733	neurotransmitter:sodium symporter activity
CLI14_RS03385	COG0189	ligase activity
CLI14_RS03390	COG0189	ligase activity
CLI14_RS03390	COG4067	protein conserved in archaea
CLI14_RS03395	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLI14_RS03400	COG2252	PERMEase
CLI14_RS03405	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CLI14_RS03410	COG1073	alpha beta
CLI14_RS03420	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CLI14_RS03425	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CLI14_RS03430	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CLI14_RS03435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLI14_RS03435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLI14_RS03455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLI14_RS03460	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CLI14_RS03465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CLI14_RS03475	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CLI14_RS03480	COG0024	Methionine aminopeptidase
CLI14_RS03485	COG0052	Belongs to the universal ribosomal protein uS2 family
CLI14_RS03490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CLI14_RS03500	COG0233	cytoplasmic translational termination
CLI14_RS03505	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CLI14_RS03510	COG0575	Belongs to the CDS family
CLI14_RS03515	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CLI14_RS03520	COG0750	zinc metalloprotease
CLI14_RS03530	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CLI14_RS03535	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLI14_RS03540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLI14_RS03550	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLI14_RS03560	COG0587	DNA-directed DNA polymerase activity
CLI14_RS03565	COG0825	malonyl-CoA metabolic process
CLI14_RS03570	COG0037	tRNA processing
CLI14_RS03580	COG0347	Belongs to the P(II) protein family
CLI14_RS03585	COG3021	interspecies interaction between organisms
CLI14_RS03595	COG1388	LysM domain
CLI14_RS03595	COG0741	lytic transglycosylase activity
CLI14_RS03600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLI14_RS03605	COG2226	methyltransferase
CLI14_RS03610	COG0328	RNA-DNA hybrid ribonuclease activity
CLI14_RS03630	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CLI14_RS03635	COG0121	glutamine amidotransferase
CLI14_RS03640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLI14_RS03645	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CLI14_RS03650	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CLI14_RS03655	COG1187	pseudouridine synthase activity
CLI14_RS03680	COG2217	Heavy metal translocating P-type atpase
CLI14_RS03680	COG2608	mercury ion transmembrane transporter activity
CLI14_RS03725	COG2747	anti-sigma28 factor FlgM
CLI14_RS03735	COG0784	Response regulator, receiver
CLI14_RS03735	COG0835	chemotaxis
CLI14_RS03745	COG1815	bacterial-type flagellum-dependent cell motility
CLI14_RS03760	COG1749	Flagellar hook protein flgE
CLI14_RS03765	COG4787	bacterial-type flagellum-dependent cell motility
CLI14_RS03775	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CLI14_RS03780	COG1706	bacterial-type flagellum-dependent cell motility
CLI14_RS03785	COG3951	Flagellar rod assembly protein muramidase FlgJ
CLI14_RS03785	COG1705	Flagellar rod assembly protein muramidase FlgJ
CLI14_RS03795	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CLI14_RS03890	COG0193	aminoacyl-tRNA hydrolase activity
CLI14_RS03895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLI14_RS03905	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CLI14_RS03910	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CLI14_RS03915	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLI14_RS03920	COG2890	protein-(glutamine-N5) methyltransferase activity
CLI14_RS03925	COG3094	Invasion gene expression up-regulator, SirB
CLI14_RS03930	COG2912	Transglutaminase-like superfamily
CLI14_RS03935	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CLI14_RS03945	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLI14_RS03950	COG2233	PERMEase
CLI14_RS03970	COG1393	Belongs to the ArsC family
CLI14_RS03975	COG4783	chaperone-mediated protein folding
CLI14_RS03995	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CLI14_RS04010	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CLI14_RS04030	COG1393	Belongs to the ArsC family
CLI14_RS04055	COG2837	iron assimilation
CLI14_RS04080	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CLI14_RS04090	COG1516	flagellar protein fliS
CLI14_RS04110	COG1677	Flagellar hook-basal body complex protein FliE
CLI14_RS04120	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLI14_RS04170	COG1987	bacterial-type flagellum assembly
CLI14_RS04175	COG1684	flagellar biosynthetic protein fliR
CLI14_RS04185	COG2840	Smr protein MutS2
CLI14_RS04190	COG2890	protein-(glutamine-N5) methyltransferase activity
CLI14_RS04195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CLI14_RS04200	COG2860	membrane
CLI14_RS04205	COG3101	peptidyl-lysine hydroxylation
CLI14_RS04215	COG0431	NADPH-dependent FMN reductase
CLI14_RS04220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLI14_RS04220	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CLI14_RS04225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLI14_RS04230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLI14_RS04235	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLI14_RS04240	COG0735	belongs to the Fur family
CLI14_RS04250	COG0583	DNA-binding transcription factor activity
CLI14_RS04260	COG1346	cytolysis
CLI14_RS04275	COG0596	Alpha beta hydrolase
CLI14_RS04280	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CLI14_RS04285	COG0033	Phosphoglucomutase
CLI14_RS04295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CLI14_RS04310	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CLI14_RS04325	COG0567	Dehydrogenase, E1 component
CLI14_RS04330	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLI14_RS04345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLI14_RS04350	COG1121	(ABC) transporter
CLI14_RS04355	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CLI14_RS04360	COG4977	sequence-specific DNA binding
CLI14_RS04365	COG1918	ferrous iron import across plasma membrane
CLI14_RS04390	COG3102	Protein conserved in bacteria
CLI14_RS04395	COG1025	Belongs to the peptidase M16 family
CLI14_RS04400	COG2062	phosphohistidine phosphatase, SixA
CLI14_RS04405	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLI14_RS04430	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CLI14_RS04435	COG0784	Response regulator, receiver
CLI14_RS04435	COG0643	Histidine kinase
CLI14_RS04435	COG2198	Histidine kinase
CLI14_RS04440	COG2201	protein-glutamate methylesterase activity
CLI14_RS04445	COG1192	Involved in chromosome partitioning
CLI14_RS04455	COG0835	chemotaxis
CLI14_RS04465	COG4133	protoheme IX ABC transporter activity
CLI14_RS04470	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLI14_RS04475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLI14_RS04485	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CLI14_RS04490	COG1138	Cytochrome C-type biogenesis protein
CLI14_RS04495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLI14_RS04510	COG2853	Lipoprotein
CLI14_RS04530	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CLI14_RS04535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLI14_RS04550	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CLI14_RS04555	COG0243	molybdopterin cofactor binding
CLI14_RS04565	COG3083	sulfuric ester hydrolase activity
CLI14_RS04570	COG3082	Protein of unknown function (DUF1414)
CLI14_RS04585	COG1757	Na H antiporter
CLI14_RS04590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLI14_RS04595	COG2095	MarC family integral membrane protein
CLI14_RS04600	COG1012	belongs to the aldehyde dehydrogenase family
CLI14_RS04600	COG1454	alcohol dehydrogenase
CLI14_RS04610	COG1530	ribonuclease E activity
CLI14_RS04615	COG0564	pseudouridine synthase activity
CLI14_RS04620	COG0424	maF-like protein
CLI14_RS04625	COG1399	metal-binding, possibly nucleic acid-binding protein
CLI14_RS04640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLI14_RS04665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLI14_RS04670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CLI14_RS04675	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLI14_RS04680	COG0470	DNA polymerase III
CLI14_RS04685	COG0084	hydrolase, TatD family'
CLI14_RS04690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI14_RS04690	COG1263	PTS System
CLI14_RS04700	COG0733	neurotransmitter:sodium symporter activity
CLI14_RS04715	COG4667	esterase of the alpha-beta hydrolase superfamily
CLI14_RS04725	COG1940	carbohydrate kinase activity
CLI14_RS04730	COG0784	Response regulator, receiver
CLI14_RS04730	COG0835	chemotaxis
CLI14_RS04735	COG1028	Short-chain dehydrogenase reductase Sdr
CLI14_RS04740	COG0616	signal peptide processing
CLI14_RS04755	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CLI14_RS04760	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CLI14_RS04765	COG0436	Aminotransferase
CLI14_RS04775	COG1169	isochorismate synthase
CLI14_RS04780	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CLI14_RS04790	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CLI14_RS04840	COG1522	sequence-specific DNA binding
CLI14_RS04845	COG1946	Acyl-CoA thioesterase
CLI14_RS04850	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CLI14_RS04865	COG3706	GGDEF domain
CLI14_RS04890	COG1022	Amp-dependent synthetase and ligase
CLI14_RS04900	COG4221	oxidoreductase activity
CLI14_RS04910	COG0745	RESPONSE REGULATOR receiver
CLI14_RS04915	COG0642	Histidine kinase
CLI14_RS04920	COG2194	sulfuric ester hydrolase activity
CLI14_RS04935	COG2985	domain, Protein
CLI14_RS04945	COG3850	Histidine kinase
CLI14_RS04945	COG5002	protein histidine kinase activity
CLI14_RS04960	COG1609	Transcriptional regulator
CLI14_RS04965	COG0129	dihydroxy-acid dehydratase activity
CLI14_RS04970	COG3265	gluconokinase activity
CLI14_RS04975	COG2610	gluconate transmembrane transporter activity
CLI14_RS04980	COG0800	Aldolase
CLI14_RS05005	COG1028	Short-chain dehydrogenase reductase Sdr
CLI14_RS05010	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLI14_RS05015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLI14_RS05045	COG1216	Glycosyl transferase, family 2
CLI14_RS05065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI14_RS05070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLI14_RS05095	COG5002	protein histidine kinase activity
CLI14_RS05095	COG0784	Response regulator, receiver
CLI14_RS05110	COG0601	transmembrane transport
CLI14_RS05115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLI14_RS05120	COG0444	Belongs to the ABC transporter superfamily
CLI14_RS05130	COG0435	Glutathione S-transferase
CLI14_RS05135	COG0280	phosphate acetyltransferase
CLI14_RS05135	COG0857	belongs to the CobB CobQ family
CLI14_RS05140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CLI14_RS05145	COG3092	negative regulation of chromosome organization
CLI14_RS05155	COG4120	Belongs to the binding-protein-dependent transport system permease family
CLI14_RS05165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLI14_RS05170	COG0653	protein targeting
CLI14_RS05175	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CLI14_RS05180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CLI14_RS05190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CLI14_RS05195	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CLI14_RS05200	COG0156	8-amino-7-oxononanoate synthase activity
CLI14_RS05205	COG2226	methyltransferase
CLI14_RS05210	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CLI14_RS05220	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CLI14_RS05225	COG2186	Transcriptional regulator
CLI14_RS05240	COG0537	adenosine 5'-monophosphoramidase activity
CLI14_RS05265	COG3150	esterase
CLI14_RS05270	COG1252	NADH dehydrogenase
CLI14_RS05285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLI14_RS05295	COG4591	ABC-type transport system involved in lipoprotein release permease component
CLI14_RS05300	COG1136	(ABC) transporter
CLI14_RS05305	COG4591	ABC-type transport system involved in lipoprotein release permease component
CLI14_RS05315	COG0658	competence protein
CLI14_RS05315	COG2333	competence protein COMEC
CLI14_RS05320	COG1132	(ABC) transporter
CLI14_RS05335	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CLI14_RS05345	COG2719	SpoVR family
CLI14_RS05350	COG2718	Belongs to the UPF0229 family
CLI14_RS05355	COG2766	serine protein kinase
CLI14_RS05360	COG3013	Belongs to the UPF0304 family
CLI14_RS05370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CLI14_RS05385	COG1882	Formate acetyltransferase
CLI14_RS05415	COG4160	amino acid transport
CLI14_RS05420	COG0708	Exodeoxyribonuclease III
CLI14_RS05425	COG0840	transmembrane signaling receptor activity
CLI14_RS05435	COG3923	Primosomal replication protein n
CLI14_RS05445	COG1199	ATP-dependent helicase activity
CLI14_RS05455	COG3012	SEC-C Motif Domain Protein
CLI14_RS05460	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CLI14_RS05465	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLI14_RS05470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLI14_RS05475	COG0215	cysteine-tRNA ligase activity
CLI14_RS05480	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CLI14_RS05485	COG0632	four-way junction helicase activity
CLI14_RS05490	COG2255	four-way junction helicase activity
CLI14_RS05495	COG1271	oxidase subunit
CLI14_RS05500	COG1294	oxidase, subunit
CLI14_RS05505	COG4890	Cyd operon protein YbgT
CLI14_RS05510	COG3790	cyd operon protein YbgE
CLI14_RS05515	COG0824	Thioesterase
CLI14_RS05520	COG0811	peptide transport
CLI14_RS05535	COG0823	Involved in the tonB-independent uptake of proteins
CLI14_RS05540	COG2885	chlorophyll binding
CLI14_RS05545	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CLI14_RS05550	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CLI14_RS05555	COG2433	Pfam Transposase IS66
CLI14_RS05575	COG5002	protein histidine kinase activity
CLI14_RS05575	COG0784	Response regulator, receiver
CLI14_RS05590	COG0582	viral genome integration into host DNA
CLI14_RS05605	COG1401	restriction endodeoxyribonuclease activity
CLI14_RS05625	COG3300	MHYT domain
CLI14_RS05625	COG5001	Diguanylate cyclase
CLI14_RS05650	COG1960	acyl-CoA dehydrogenase activity
CLI14_RS05655	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CLI14_RS05685	COG0247	lactate metabolic process
CLI14_RS05685	COG0277	FAD linked oxidase domain protein
CLI14_RS05700	COG2986	histidine ammonia-lyase
CLI14_RS05710	COG0010	Belongs to the arginase family
CLI14_RS05715	COG1228	amidohydrolase
CLI14_RS05725	COG3097	Belongs to the UPF0267 family
CLI14_RS05730	COG3099	Belongs to the UPF0263 family
CLI14_RS05735	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLI14_RS05745	COG0417	DNA replication proofreading
CLI14_RS05750	COG2197	response regulator
CLI14_RS05755	COG0322	excinuclease ABC activity
CLI14_RS05795	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CLI14_RS05800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLI14_RS05800	COG0072	phenylalanine-tRNA ligase activity
CLI14_RS05805	COG0776	regulation of translation
CLI14_RS05815	COG0500	methyltransferase
CLI14_RS05830	COG5001	Diguanylate cyclase
CLI14_RS05840	COG1346	cytolysis
CLI14_RS05845	COG1380	Effector of murein hydrolase LrgA
CLI14_RS05850	COG2925	Exonuclease
CLI14_RS05855	COG1823	symporter activity
CLI14_RS05860	COG0702	epimerase
CLI14_RS05890	COG2994	toxin metabolic process
CLI14_RS05895	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CLI14_RS05895	COG3064	Membrane
CLI14_RS05895	COG1073	alpha beta
CLI14_RS05900	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CLI14_RS05905	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CLI14_RS05920	COG2988	succinylglutamate desuccinylase activity
CLI14_RS05925	COG4139	cobalamin transport
CLI14_RS05930	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CLI14_RS05950	COG0583	DNA-binding transcription factor activity
CLI14_RS05960	COG1451	nucleotide metabolic process
CLI14_RS05975	COG3063	Type IV pilus biogenesis stability protein PilW
CLI14_RS06000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLI14_RS06015	COG3290	protein histidine kinase activity
CLI14_RS06020	COG4565	transcriptional regulatory protein
CLI14_RS06030	COG0835	chemotaxis
CLI14_RS06030	COG0784	Response regulator, receiver
CLI14_RS06070	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CLI14_RS06145	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLI14_RS06165	COG1716	ATPase activity
CLI14_RS06190	COG4991	sh3 domain protein
CLI14_RS06190	COG3064	Membrane
CLI14_RS06190	COG0515	serine threonine protein kinase
CLI14_RS06240	COG2433	Pfam Transposase IS66
CLI14_RS06260	COG0251	oxidation-reduction process
CLI14_RS06270	COG1294	oxidase, subunit
CLI14_RS06290	COG3220	belongs to the UPF0276 family
CLI14_RS06315	COG0840	transmembrane signaling receptor activity
CLI14_RS06325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLI14_RS06330	COG2200	EAL domain
CLI14_RS06335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLI14_RS06340	COG1263	PTS System
CLI14_RS06340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI14_RS06350	COG1621	beta-fructofuranosidase activity
CLI14_RS06355	COG0840	transmembrane signaling receptor activity
CLI14_RS06365	COG1054	Belongs to the UPF0176 family
CLI14_RS06370	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CLI14_RS06375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLI14_RS06385	COG0848	biopolymer transport protein
CLI14_RS06390	COG0811	peptide transport
CLI14_RS06395	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CLI14_RS06400	COG3721	Heme iron utilization protein
CLI14_RS06405	COG0748	coenzyme F420 binding
CLI14_RS06410	COG1629	transport
CLI14_RS06410	COG4771	TonB-dependent receptor
CLI14_RS06415	COG1940	carbohydrate kinase activity
CLI14_RS06445	COG2989	Protein conserved in bacteria
CLI14_RS06450	COG3108	Peptidase M15
CLI14_RS06455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLI14_RS06470	COG1846	Transcriptional regulator
CLI14_RS06475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLI14_RS06490	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CLI14_RS06495	COG1448	Aminotransferase
CLI14_RS06500	COG2770	Histidine kinase
CLI14_RS06500	COG3437	response regulator, receiver
CLI14_RS06505	COG0840	transmembrane signaling receptor activity
CLI14_RS06510	COG0745	RESPONSE REGULATOR receiver
CLI14_RS06520	COG2198	Histidine kinase
CLI14_RS06520	COG0643	Histidine kinase
CLI14_RS06530	COG0835	chemotaxis
CLI14_RS06535	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLI14_RS06540	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CLI14_RS06545	COG2201	protein-glutamate methylesterase activity
CLI14_RS06555	COG0017	Asparaginyl-tRNA synthetase
CLI14_RS06560	COG0840	transmembrane signaling receptor activity
CLI14_RS06565	COG0720	synthase
CLI14_RS06570	COG2356	endonuclease I
CLI14_RS06580	COG1760	l-serine dehydratase
CLI14_RS06585	COG0814	amino acid
CLI14_RS06590	COG0494	nUDIX hydrolase
CLI14_RS06595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLI14_RS06610	COG3106	COG3106 Predicted ATPase
CLI14_RS06615	COG3768	UPF0283 membrane protein
CLI14_RS06625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLI14_RS06645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLI14_RS06655	COG0471	metal ion transport
CLI14_RS06660	COG4191	Histidine kinase
CLI14_RS06660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI14_RS06675	COG1278	Cold shock
CLI14_RS06680	COG3005	denitrification pathway
CLI14_RS06685	COG0243	molybdopterin cofactor binding
CLI14_RS06690	COG0513	Belongs to the DEAD box helicase family
CLI14_RS06695	COG2723	6-phospho-beta-galactosidase activity
CLI14_RS06700	COG1609	Transcriptional regulator
CLI14_RS06750	COG5001	Diguanylate cyclase
CLI14_RS06750	COG5002	protein histidine kinase activity
CLI14_RS06770	COG1643	Atp-dependent helicase
CLI14_RS06780	COG0583	DNA-binding transcription factor activity
CLI14_RS06785	COG0477	Major facilitator Superfamily
CLI14_RS06805	COG0673	inositol 2-dehydrogenase activity
CLI14_RS06810	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLI14_RS06815	COG0517	IMP dehydrogenase activity
CLI14_RS06815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CLI14_RS06820	COG2176	DNA-directed DNA polymerase activity
CLI14_RS06830	COG3718	enzyme involved in inositol metabolism
CLI14_RS06835	COG3962	Belongs to the TPP enzyme family
CLI14_RS06840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLI14_RS06865	COG0673	inositol 2-dehydrogenase activity
CLI14_RS06870	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CLI14_RS06895	COG2433	Pfam Transposase IS66
CLI14_RS06910	COG1204	response to ionizing radiation
CLI14_RS06930	COG2433	Pfam Transposase IS66
CLI14_RS06940	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CLI14_RS06945	COG1280	lysine exporter protein (LysE YggA)
CLI14_RS06950	COG1115	amino acid carrier protein
CLI14_RS06965	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLI14_RS06975	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CLI14_RS06985	COG0625	glutathione transferase activity
CLI14_RS07015	COG0811	peptide transport
CLI14_RS07020	COG0811	peptide transport
CLI14_RS07025	COG0848	biopolymer transport protein
CLI14_RS07040	COG4667	esterase of the alpha-beta hydrolase superfamily
CLI14_RS07045	COG1793	dna ligase
CLI14_RS07060	COG3001	Fructosamine kinase
CLI14_RS07070	COG0791	NLP P60 protein
CLI14_RS07075	COG0840	transmembrane signaling receptor activity
CLI14_RS07085	COG3148	PFAM DTW domain containing protein
CLI14_RS07090	COG1940	carbohydrate kinase activity
CLI14_RS07100	COG1763	Mo-molybdopterin cofactor biosynthetic process
CLI14_RS07105	COG0746	molybdenum cofactor guanylyltransferase activity
CLI14_RS07110	COG3842	ATPase activity
CLI14_RS07120	COG1840	ABC-type Fe3 transport system, periplasmic component
CLI14_RS07125	COG2271	Major facilitator Superfamily
CLI14_RS07135	COG2197	response regulator
CLI14_RS07140	COG0488	(ABC) transporter
CLI14_RS07145	COG0004	ammonium transporteR
CLI14_RS07150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CLI14_RS07160	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CLI14_RS07165	COG1177	transmembrane transport
CLI14_RS07170	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLI14_RS07175	COG3842	ATPase activity
CLI14_RS07200	COG0589	response to stress
CLI14_RS07205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLI14_RS07220	COG2217	Heavy metal translocating P-type atpase
CLI14_RS07230	COG2010	Cytochrome c
CLI14_RS07245	COG3278	Belongs to the heme-copper respiratory oxidase family
CLI14_RS07275	COG3120	sequence-specific DNA binding
CLI14_RS07280	COG1067	ATP-dependent peptidase activity
CLI14_RS07285	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLI14_RS07300	COG0488	(ABC) transporter
CLI14_RS07310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CLI14_RS07310	COG0116	Belongs to the methyltransferase superfamily
CLI14_RS07320	COG0167	dihydroorotate dehydrogenase activity
CLI14_RS07325	COG2902	Dehydrogenase
CLI14_RS07335	COG0308	aminopeptidase N
CLI14_RS07350	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CLI14_RS07355	COG1956	GAF domain-containing protein
CLI14_RS07360	COG1132	(ABC) transporter
CLI14_RS07365	COG2995	paraquat-inducible protein a
CLI14_RS07370	COG3008	intermembrane lipid transfer
CLI14_RS07380	COG2996	Protein conserved in bacteria
CLI14_RS07400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLI14_RS07405	COG1666	GTP binding
CLI14_RS07415	COG1648	precorrin-2 dehydrogenase activity
CLI14_RS07415	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CLI14_RS07420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI14_RS07425	COG4597	amino acid ABC transporter
CLI14_RS07430	COG0765	amino acid transport
CLI14_RS07435	COG1126	abc transporter atp-binding protein
CLI14_RS07440	COG0670	Belongs to the BI1 family
CLI14_RS07445	COG2920	part of a sulfur-relay system
CLI14_RS07450	COG1254	Belongs to the acylphosphatase family
CLI14_RS07455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CLI14_RS07465	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CLI14_RS07495	COG0602	queuosine metabolic process
CLI14_RS07500	COG0561	phosphatase activity
CLI14_RS07520	COG2828	Protein conserved in bacteria
CLI14_RS07525	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CLI14_RS07530	COG0372	Belongs to the citrate synthase family
CLI14_RS07535	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CLI14_RS07565	COG0745	RESPONSE REGULATOR receiver
CLI14_RS07570	COG5002	protein histidine kinase activity
CLI14_RS07575	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CLI14_RS07580	COG1902	pentaerythritol trinitrate reductase activity
CLI14_RS07595	COG1129	ABC transporter
CLI14_RS07615	COG1342	Belongs to the UPF0251 family
CLI14_RS07625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLI14_RS07635	COG2207	Transcriptional regulator
CLI14_RS07640	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLI14_RS07640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLI14_RS07640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_RS07665	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CLI14_RS07675	COG3051	citrate lyase alpha subunit
CLI14_RS07680	COG2301	Belongs to the HpcH HpaI aldolase family
CLI14_RS07690	COG4565	transcriptional regulatory protein
CLI14_RS07700	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CLI14_RS07705	COG5016	pyruvate
CLI14_RS07705	COG0511	ligase activity, forming carbon-carbon bonds
CLI14_RS07720	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CLI14_RS07740	COG0840	transmembrane signaling receptor activity
CLI14_RS07750	COG0840	transmembrane signaling receptor activity
CLI14_RS07760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CLI14_RS07765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLI14_RS07770	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLI14_RS07800	COG0840	transmembrane signaling receptor activity
CLI14_RS07825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CLI14_RS07840	COG4181	ATPase activity
CLI14_RS07845	COG0534	Mate efflux family protein
CLI14_RS07850	COG0702	epimerase
CLI14_RS07860	COG2814	Major facilitator Superfamily
CLI14_RS07865	COG1187	pseudouridine synthase activity
CLI14_RS07870	COG1061	Type III restriction enzyme res subunit
CLI14_RS07885	COG2205	protein histidine kinase activity
CLI14_RS07890	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CLI14_RS07905	COG0513	Belongs to the DEAD box helicase family
CLI14_RS07925	COG0737	Belongs to the 5'-nucleotidase family
CLI14_RS07935	COG3313	Fe-S protein
CLI14_RS07945	COG4134	Bacterial extracellular solute-binding protein
CLI14_RS07950	COG4135	transport system, permease component
CLI14_RS07955	COG4136	ATPase activity
CLI14_RS07960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLI14_RS07985	COG0564	pseudouridine synthase activity
CLI14_RS07990	COG0733	neurotransmitter:sodium symporter activity
CLI14_RS08000	COG0626	cystathionine gamma-synthase activity
CLI14_RS08005	COG0519	Catalyzes the synthesis of GMP from XMP
CLI14_RS08020	COG1842	Phage shock protein A
CLI14_RS08025	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CLI14_RS08040	COG4171	peptide transport system, permease
CLI14_RS08050	COG4172	Belongs to the ABC transporter superfamily
CLI14_RS08065	COG1227	inorganic diphosphatase activity
CLI14_RS08075	COG0243	molybdopterin cofactor binding
CLI14_RS08080	COG3005	denitrification pathway
CLI14_RS08085	COG4459	periplasmic nitrate reductase
CLI14_RS08090	COG2116	formate transmembrane transporter activity
CLI14_RS08115	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CLI14_RS08120	COG1435	thymidine kinase activity
CLI14_RS08125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CLI14_RS08130	COG1801	Protein of unknown function DUF72
CLI14_RS08140	COG4106	trans-aconitate 2-methyltransferase activity
CLI14_RS08145	COG0500	methyltransferase
CLI14_RS08150	COG4067	protein conserved in archaea
CLI14_RS08150	COG0189	ligase activity
CLI14_RS08165	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CLI14_RS08170	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CLI14_RS08180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CLI14_RS08185	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CLI14_RS08190	COG0745	RESPONSE REGULATOR receiver
CLI14_RS08200	COG1609	Transcriptional regulator
CLI14_RS08205	COG3070	regulator of competence-specific genes
CLI14_RS08225	COG0297	glycogen (starch) synthase activity
CLI14_RS08230	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CLI14_RS08235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLI14_RS08250	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CLI14_RS08255	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CLI14_RS08260	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CLI14_RS08265	COG0542	response to heat
CLI14_RS08270	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CLI14_RS08275	COG1278	Cold shock
CLI14_RS08285	COG1187	pseudouridine synthase activity
CLI14_RS08290	COG0140	phosphoribosyl-ATP diphosphatase activity
CLI14_RS08290	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CLI14_RS08295	COG0107	imidazoleglycerol-phosphate synthase activity
CLI14_RS08300	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CLI14_RS08305	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CLI14_RS08310	COG0131	Imidazoleglycerol-phosphate dehydratase
CLI14_RS08310	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CLI14_RS08315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLI14_RS08320	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CLI14_RS08325	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CLI14_RS08330	COG1757	Na H antiporter
CLI14_RS08335	COG2916	Histone family protein nucleoid-structuring protein H-NS
CLI14_RS08340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLI14_RS08350	COG0482	sulfurtransferase activity
CLI14_RS08355	COG2915	High frequency lysogenization protein hflD homolog
CLI14_RS08360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CLI14_RS08365	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CLI14_RS08375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI14_RS08375	COG4191	Histidine kinase
CLI14_RS08390	COG3070	regulator of competence-specific genes
CLI14_RS08400	COG2431	L-lysine efflux transmembrane transporter activity
CLI14_RS08410	COG0076	glutamate decarboxylase activity
CLI14_RS08415	COG1737	Transcriptional regulator
CLI14_RS08425	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CLI14_RS08430	COG2985	domain, Protein
CLI14_RS08430	COG3273	potassium ion transport
CLI14_RS08435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CLI14_RS08445	COG0281	malic enzyme
CLI14_RS08455	COG2949	membrane
CLI14_RS08475	COG0492	ferredoxin-NADP+ reductase activity
CLI14_RS08480	COG4988	ABC transporter
CLI14_RS08485	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CLI14_RS08500	COG1595	DNA-templated transcription, initiation
CLI14_RS08515	COG1187	pseudouridine synthase activity
CLI14_RS08520	COG0009	L-threonylcarbamoyladenylate synthase
CLI14_RS08525	COG0613	PHP domain protein
CLI14_RS08535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLI14_RS08540	COG0512	Glutamine amidotransferase of anthranilate synthase
CLI14_RS08545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLI14_RS08550	COG0135	phosphoribosylanthranilate isomerase activity
CLI14_RS08550	COG0134	indole-3-glycerol-phosphate synthase activity
CLI14_RS08555	COG0133	tryptophan synthase activity
CLI14_RS08560	COG0159	tryptophan synthase activity
CLI14_RS08590	COG2350	Protein conserved in bacteria
CLI14_RS08600	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CLI14_RS08605	COG0583	DNA-binding transcription factor activity
CLI14_RS08620	COG2200	EAL domain
CLI14_RS08620	COG2199	diguanylate cyclase activity
CLI14_RS08620	COG2203	Gaf domain
CLI14_RS08630	COG1032	radical SAM domain protein
CLI14_RS08640	COG2268	Band 7 protein
CLI14_RS08650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CLI14_RS08665	COG0300	oxidoreductase activity
CLI14_RS08675	COG0501	Belongs to the peptidase M48B family
CLI14_RS08685	COG1674	ftsk spoiiie
CLI14_RS08690	COG1522	sequence-specific DNA binding
CLI14_RS08695	COG0686	Belongs to the AlaDH PNT family
CLI14_RS08705	COG0583	DNA-binding transcription factor activity
CLI14_RS08720	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CLI14_RS08725	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CLI14_RS08730	COG0776	regulation of translation
CLI14_RS08735	COG0539	negative regulation of cytoplasmic translation
CLI14_RS08740	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CLI14_RS08745	COG1555	photosystem II stabilization
CLI14_RS08750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLI14_RS08755	COG0776	regulation of translation
CLI14_RS08760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CLI14_RS08765	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CLI14_RS08775	COG0544	peptidyl-prolyl cis-trans isomerase activity
CLI14_RS08795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CLI14_RS08800	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CLI14_RS08805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CLI14_RS08815	COG1653	transport
CLI14_RS08820	COG2205	protein histidine kinase activity
CLI14_RS08830	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CLI14_RS08835	COG1760	l-serine dehydratase
CLI14_RS08845	COG0513	Belongs to the DEAD box helicase family
CLI14_RS08855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLI14_RS08870	COG4628	conserved protein (DUF2132)
CLI14_RS08895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLI14_RS08900	COG0583	DNA-binding transcription factor activity
CLI14_RS08905	COG2951	lytic endotransglycosylase activity
CLI14_RS08910	COG3100	YcgL domain-containing protein
CLI14_RS08920	COG2894	cell division
CLI14_RS08925	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CLI14_RS08930	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CLI14_RS08935	COG0318	PFAM AMP-dependent synthetase and ligase
CLI14_RS08940	COG0596	Alpha beta hydrolase
CLI14_RS08955	COG1214	PFAM Peptidase M22, glycoprotease
CLI14_RS08960	COG1199	ATP-dependent helicase activity
CLI14_RS08970	COG0788	formyltetrahydrofolate deformylase activity
CLI14_RS08975	COG1902	pentaerythritol trinitrate reductase activity
CLI14_RS08975	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLI14_RS08980	COG0616	signal peptide processing
CLI14_RS08985	COG0252	asparaginase activity
CLI14_RS08990	COG3139	Protein of unknown function (DUF1315)
CLI14_RS09000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLI14_RS09015	COG2226	methyltransferase
CLI14_RS09030	COG2983	Belongs to the UPF0260 family
CLI14_RS09040	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CLI14_RS09055	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLI14_RS09060	COG2832	Protein of unknown function (DUF454)
CLI14_RS09070	COG0745	RESPONSE REGULATOR receiver
CLI14_RS09075	COG0583	DNA-binding transcription factor activity
CLI14_RS09080	COG0778	Nitroreductase
CLI14_RS09085	COG1024	Enoyl-CoA hydratase
CLI14_RS09085	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLI14_RS09090	COG0183	Belongs to the thiolase family
CLI14_RS09105	COG1595	DNA-templated transcription, initiation
CLI14_RS09115	COG2067	long-chain fatty acid transport protein
CLI14_RS09120	COG2067	long-chain fatty acid transport protein
CLI14_RS09125	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CLI14_RS09130	COG2982	Protein involved in outer membrane biogenesis
CLI14_RS09135	COG0572	uridine kinase
CLI14_RS09140	COG0489	protein tyrosine kinase activity
CLI14_RS09145	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLI14_RS09145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLI14_RS09155	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CLI14_RS09165	COG0617	tRNA 3'-terminal CCA addition
CLI14_RS09165	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CLI14_RS09165	COG0517	IMP dehydrogenase activity
CLI14_RS09170	COG2199	diguanylate cyclase activity
CLI14_RS09175	COG0314	molybdopterin synthase activity
CLI14_RS09180	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CLI14_RS09190	COG0521	Mo-molybdopterin cofactor biosynthetic process
CLI14_RS09195	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CLI14_RS09200	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CLI14_RS09205	COG2198	Histidine kinase
CLI14_RS09210	COG2204	response regulator
CLI14_RS09215	COG0556	nucleotide-excision repair
CLI14_RS09230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLI14_RS09235	COG1028	Short-chain dehydrogenase reductase Sdr
CLI14_RS09240	COG1169	isochorismate synthase
CLI14_RS09245	COG1021	2,3-dihydroxybenzoate-AMP ligase
CLI14_RS09250	COG1535	isochorismatase
CLI14_RS09250	COG3433	isochorismatase activity
CLI14_RS09270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI14_RS09280	COG2382	esterase
CLI14_RS09285	COG4774	siderophore transport
CLI14_RS09285	COG1629	transport
CLI14_RS09295	COG4657	Part of a membrane complex involved in electron transport
CLI14_RS09300	COG2878	Part of a membrane complex involved in electron transport
CLI14_RS09305	COG4656	Part of a membrane complex involved in electron transport
CLI14_RS09310	COG4658	electron transport chain
CLI14_RS09315	COG4659	FMN binding
CLI14_RS09320	COG4660	Part of a membrane complex involved in electron transport
CLI14_RS09325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CLI14_RS09330	COG0346	lactoylglutathione lyase activity
CLI14_RS09340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLI14_RS09345	COG2056	Na+-H+ antiporter family
CLI14_RS09350	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CLI14_RS09355	COG1286	toxin biosynthetic process
CLI14_RS09360	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CLI14_RS09365	COG0285	dihydrofolate synthase activity
CLI14_RS09370	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CLI14_RS09375	COG0101	tRNA pseudouridine synthase activity
CLI14_RS09385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLI14_RS09390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI14_RS09390	COG2190	(PTS) system
CLI14_RS09390	COG1263	PTS System
CLI14_RS09395	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CLI14_RS09400	COG1846	Transcriptional regulator
CLI14_RS09400	COG1940	carbohydrate kinase activity
CLI14_RS09405	COG4651	solute:proton antiporter activity
CLI14_RS09405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLI14_RS09410	COG0367	asparagine synthase
CLI14_RS09420	COG3104	oligopeptide transport
CLI14_RS09425	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CLI14_RS09435	COG0326	Molecular chaperone. Has ATPase activity
CLI14_RS09440	COG3710	Transcriptional regulator
CLI14_RS09455	COG0622	Phosphoesterase
CLI14_RS09460	COG1090	epimerase
CLI14_RS09465	COG3118	belongs to the thioredoxin family
CLI14_RS09470	COG0330	HflC and HflK could
CLI14_RS09480	COG0789	Transcriptional regulator
CLI14_RS09500	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLI14_RS09505	COG3115	cell septum assembly
CLI14_RS09510	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CLI14_RS09515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLI14_RS09520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_RS09525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLI14_RS09530	COG2190	(PTS) system
CLI14_RS09535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLI14_RS09540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLI14_RS09545	COG1702	phosphate starvation-inducible protein PhoH
CLI14_RS09550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CLI14_RS09555	COG4535	Mg2 and Co2 transporter CorC
CLI14_RS09560	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CLI14_RS09565	COG2888	peptidyl-tyrosine sulfation
CLI14_RS09570	COG0495	leucyl-tRNA aminoacylation
CLI14_RS09575	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CLI14_RS09580	COG1466	dna polymerase III delta subunit
CLI14_RS09585	COG0799	negative regulation of ribosome biogenesis
CLI14_RS09590	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CLI14_RS09595	COG0768	penicillin binding
CLI14_RS09600	COG0772	Belongs to the SEDS family
CLI14_RS09605	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CLI14_RS09610	COG1686	Belongs to the peptidase S11 family
CLI14_RS09615	COG2921	Belongs to the UPF0250 family
CLI14_RS09620	COG0321	lipoyl(octanoyl) transferase activity
CLI14_RS09625	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CLI14_RS09655	COG1596	polysaccharide export
CLI14_RS09660	COG0489	protein tyrosine kinase activity
CLI14_RS09690	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CLI14_RS09700	COG1045	serine acetyltransferase
CLI14_RS09740	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CLI14_RS09745	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CLI14_RS09750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLI14_RS09755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLI14_RS09760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLI14_RS09795	COG2205	protein histidine kinase activity
CLI14_RS09800	COG0745	RESPONSE REGULATOR receiver
CLI14_RS09805	COG0366	Alpha amylase catalytic
CLI14_RS09810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLI14_RS09810	COG1263	PTS System
CLI14_RS09825	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CLI14_RS09830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLI14_RS09835	COG2011	ABC-type metal ion transport system permease component
CLI14_RS09840	COG1464	Belongs to the NlpA lipoprotein family
CLI14_RS09845	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CLI14_RS09870	COG1611	Belongs to the LOG family
CLI14_RS09875	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLI14_RS09880	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CLI14_RS09885	COG2363	Small membrane protein
CLI14_RS09890	COG0583	DNA-binding transcription factor activity
CLI14_RS09895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLI14_RS09895	COG0301	tRNA thio-modification
CLI14_RS09905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CLI14_RS09910	COG1722	exodeoxyribonuclease VII activity
CLI14_RS09915	COG0142	geranyltranstransferase activity
CLI14_RS09920	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CLI14_RS09925	COG0564	pseudouridine synthase activity
CLI14_RS09930	COG3098	single-species biofilm formation
CLI14_RS09960	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CLI14_RS09965	COG0254	rRNA binding
CLI14_RS09970	COG1720	tRNA m6t6A37 methyltransferase activity
CLI14_RS09975	COG0442	prolyl-tRNA aminoacylation
CLI14_RS09980	COG2979	Protein of unknown function (DUF533)
CLI14_RS10000	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLI14_RS10000	COG0047	phosphoribosylformylglycinamidine synthase activity
CLI14_RS10010	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CLI14_RS10015	COG0590	tRNA wobble adenosine to inosine editing
CLI14_RS10020	COG0583	DNA-binding transcription factor activity
CLI14_RS10030	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CLI14_RS10035	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CLI14_RS10065	COG0484	heat shock protein binding
CLI14_RS10070	COG0443	Heat shock 70 kDa protein
CLI14_RS10075	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CLI14_RS10080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLI14_RS10090	COG3033	Beta-eliminating lyase
CLI14_RS10095	COG0497	DNA recombination
CLI14_RS10100	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLI14_RS10105	COG2914	Belongs to the UPF0125 (RnfH) family
CLI14_RS10110	COG2867	negative regulation of translational initiation
CLI14_RS10125	COG0582	viral genome integration into host DNA
CLI14_RS10130	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CLI14_RS10150	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CLI14_RS10155	COG1715	Restriction endonuclease
CLI14_RS10170	COG2003	Belongs to the UPF0758 family
CLI14_RS10300	COG1115	amino acid carrier protein
CLI14_RS10305	COG1584	GPR1 FUN34 yaaH family protein
CLI14_RS10315	COG0351	phosphomethylpyrimidine kinase
CLI14_RS10320	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CLI14_RS10320	COG0519	Catalyzes the synthesis of GMP from XMP
CLI14_RS10325	COG0517	IMP dehydrogenase activity
CLI14_RS10325	COG0516	GMP reductase activity
CLI14_RS10340	COG1160	GTP binding
CLI14_RS10345	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLI14_RS10350	COG2976	Protein conserved in bacteria
CLI14_RS10355	COG0124	histidyl-tRNA synthetase
CLI14_RS10360	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CLI14_RS10365	COG1426	Protein conserved in bacteria
CLI14_RS10380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CLI14_RS10385	COG2975	iron-sulfur cluster assembly
CLI14_RS10390	COG0633	Ferredoxin
CLI14_RS10395	COG0443	Heat shock 70 kDa protein
CLI14_RS10405	COG0316	Belongs to the HesB IscA family
CLI14_RS10410	COG0822	iron-sulfur transferase activity
CLI14_RS10420	COG1959	2 iron, 2 sulfur cluster binding
CLI14_RS10425	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CLI14_RS10430	COG0483	inositol monophosphate 1-phosphatase activity
CLI14_RS10435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLI14_RS10440	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLI14_RS10445	COG1862	Preprotein translocase
CLI14_RS10450	COG0343	queuine tRNA-ribosyltransferase activity
CLI14_RS10460	COG0517	IMP dehydrogenase activity
CLI14_RS10470	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CLI14_RS10475	COG0583	DNA-binding transcription factor activity
CLI14_RS10480	COG0450	alkyl hydroperoxide reductase
CLI14_RS10490	COG0704	Plays a role in the regulation of phosphate uptake
CLI14_RS10495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLI14_RS10500	COG0581	inorganic phosphate transmembrane transporter activity
CLI14_RS10510	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CLI14_RS10515	COG0248	Ppx GppA phosphatase
CLI14_RS10525	COG5002	protein histidine kinase activity
CLI14_RS10530	COG0745	RESPONSE REGULATOR receiver
CLI14_RS10540	COG0826	peptidase U32
CLI14_RS10545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLI14_RS10590	COG0542	response to heat
CLI14_RS10595	COG1496	oxidoreductase activity
CLI14_RS10605	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLI14_RS10610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLI14_RS10615	COG0077	Prephenate dehydratase
CLI14_RS10615	COG1605	Chorismate mutase
CLI14_RS10620	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CLI14_RS10625	COG5001	Diguanylate cyclase
CLI14_RS10630	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CLI14_RS10635	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CLI14_RS10645	COG0488	(ABC) transporter
CLI14_RS10655	COG1605	Chorismate mutase
CLI14_RS10655	COG0287	Prephenate dehydrogenase
CLI14_RS10660	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLI14_RS10665	COG3275	phosphorelay sensor kinase activity
CLI14_RS10670	COG3279	Response regulator of the LytR AlgR family
CLI14_RS10680	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CLI14_RS10685	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CLI14_RS10700	COG1966	Carbon starvation protein
CLI14_RS10705	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CLI14_RS10710	COG1047	Peptidyl-prolyl cis-trans
CLI14_RS10715	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CLI14_RS10725	COG0196	riboflavin kinase activity
CLI14_RS10730	COG0728	peptidoglycan biosynthetic process
CLI14_RS10735	COG0268	Binds directly to 16S ribosomal RNA
CLI14_RS10740	COG0640	Transcriptional regulator
CLI14_RS10745	COG0583	DNA-binding transcription factor activity
CLI14_RS10750	COG1283	sodium-dependent phosphate transmembrane transporter activity
CLI14_RS10755	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLI14_RS10760	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLI14_RS10790	COG2433	Pfam Transposase IS66
CLI14_RS10830	COG3550	peptidyl-serine autophosphorylation
CLI14_RS10845	COG3422	double-strand break repair
CLI14_RS10865	COG2433	Pfam Transposase IS66
CLI14_RS10875	COG2194	sulfuric ester hydrolase activity
CLI14_RS10880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CLI14_RS10905	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLI14_RS10915	COG0730	response to heat
CLI14_RS10925	COG0494	nUDIX hydrolase
CLI14_RS10935	COG0667	Aldo Keto reductase
CLI14_RS10945	COG2204	response regulator
CLI14_RS10950	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CLI14_RS10965	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CLI14_RS10970	COG0513	Belongs to the DEAD box helicase family
CLI14_RS10995	COG3153	acetyltransferase
CLI14_RS11000	COG3154	lipid carrier protein
CLI14_RS11010	COG0826	peptidase U32
CLI14_RS11015	COG0826	peptidase U32
CLI14_RS11025	COG1846	Transcriptional regulator
CLI14_RS11040	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CLI14_RS11045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CLI14_RS11055	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CLI14_RS11060	COG0195	Participates in both transcription termination and antitermination
CLI14_RS11065	COG0779	Required for maturation of 30S ribosomal subunits
CLI14_RS11080	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CLI14_RS11085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLI14_RS11090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CLI14_RS11095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLI14_RS11100	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CLI14_RS11105	COG1534	Rna-binding protein
CLI14_RS11110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLI14_RS11120	COG2027	D-alanyl-D-alanine carboxypeptidase
CLI14_RS11125	COG2239	Acts as a magnesium transporter
CLI14_RS11135	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLI14_RS11140	COG0739	heme binding
CLI14_RS11155	COG0316	Belongs to the HesB IscA family
CLI14_RS11160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CLI14_RS11165	COG0628	permease
CLI14_RS11175	COG0784	Response regulator, receiver
CLI14_RS11175	COG2205	protein histidine kinase activity
CLI14_RS11190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLI14_RS11195	COG0444	Belongs to the ABC transporter superfamily
CLI14_RS11200	COG4608	Belongs to the ABC transporter superfamily
CLI14_RS11210	COG2971	BadF BadG BcrA BcrD
CLI14_RS11225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLI14_RS11240	COG1840	ABC-type Fe3 transport system, periplasmic component
CLI14_RS11245	COG0004	ammonium transporteR
CLI14_RS11255	COG3112	Uncharacterised protein family (UPF0231)
CLI14_RS11260	COG3835	regulator
CLI14_RS11265	COG2610	gluconate transmembrane transporter activity
CLI14_RS11270	COG1929	Belongs to the glycerate kinase type-1 family
CLI14_RS11275	COG1049	propionate catabolic process, 2-methylcitrate cycle
CLI14_RS11280	COG1752	Esterase of the alpha-beta hydrolase superfamily
CLI14_RS11285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLI14_RS11290	COG1643	Atp-dependent helicase
CLI14_RS11295	COG1489	DNA binding
CLI14_RS11300	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CLI14_RS11305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLI14_RS11315	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CLI14_RS11325	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CLI14_RS11335	COG0842	Transport permease protein
CLI14_RS11340	COG1131	(ABC) transporter
CLI14_RS11345	COG0659	secondary active sulfate transmembrane transporter activity
CLI14_RS11350	COG0288	reversible hydration of carbon dioxide
CLI14_RS11365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLI14_RS11370	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLI14_RS11375	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CLI14_RS11380	COG2186	Transcriptional regulator
CLI14_RS11385	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CLI14_RS11390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLI14_RS11395	COG4974	Belongs to the 'phage' integrase family
CLI14_RS11400	COG0716	FMN binding
CLI14_RS11410	COG0157	Belongs to the NadC ModD family
CLI14_RS11425	COG1459	type II secretion system
CLI14_RS11435	COG0237	dephospho-CoA kinase activity
CLI14_RS11440	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CLI14_RS11450	COG0335	large ribosomal subunit rRNA binding
CLI14_RS11455	COG0336	Belongs to the RNA methyltransferase TrmD family
CLI14_RS11460	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CLI14_RS11465	COG0228	four-way junction DNA binding
CLI14_RS11470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLI14_RS11475	COG4137	Cytochrome C assembly protein
CLI14_RS11480	COG4536	flavin adenine dinucleotide binding
CLI14_RS11485	COG1854	S-ribosylhomocysteine lyase activity
CLI14_RS11495	COG0612	Peptidase, M16
CLI14_RS11500	COG1238	metal cluster binding
CLI14_RS11510	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CLI14_RS11515	COG0511	ligase activity, forming carbon-carbon bonds
CLI14_RS11515	COG5016	pyruvate
CLI14_RS11520	COG3630	sodium ion export across plasma membrane
CLI14_RS11560	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CLI14_RS11565	COG0527	aspartate kinase activity
CLI14_RS11570	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLI14_RS11575	COG2137	regulation of response to DNA damage stimulus
CLI14_RS11580	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CLI14_RS11585	COG1546	Belongs to the CinA family
CLI14_RS11590	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CLI14_RS11595	COG4208	sulfate ABC transporter
CLI14_RS11605	COG4150	thiosulfate binding
CLI14_RS11615	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLI14_RS11620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLI14_RS11625	COG1388	LysM domain
CLI14_RS11625	COG4942	peptidase
CLI14_RS11630	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CLI14_RS11635	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CLI14_RS11640	COG0585	pseudouridine synthase activity
CLI14_RS11645	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CLI14_RS11650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CLI14_RS11655	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CLI14_RS11660	COG1968	undecaprenyl-diphosphatase activity
CLI14_RS11665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CLI14_RS11670	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLI14_RS11685	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CLI14_RS11690	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CLI14_RS11695	COG1610	YqeY-like protein
CLI14_RS11700	COG0358	DNA primase activity
CLI14_RS11720	COG3550	peptidyl-serine autophosphorylation
CLI14_RS11740	COG0210	DNA helicase
CLI14_RS11755	COG2433	Pfam Transposase IS66
CLI14_RS11900	COG4584	PFAM Integrase catalytic
CLI14_RS11905	COG1484	DNA-dependent DNA replication
CLI14_RS12055	COG4104	PAAR repeat-containing protein
CLI14_RS12060	COG3501	Rhs element vgr protein
CLI14_RS12080	COG4932	domain protein
CLI14_RS12080	COG5492	domain, Protein
CLI14_RS12090	COG1349	DNA-binding transcription factor activity
CLI14_RS12100	COG3706	GGDEF domain
CLI14_RS12120	COG0668	transmembrane transport
CLI14_RS12125	COG0191	fructose-bisphosphate aldolase activity
CLI14_RS12135	COG0126	phosphoglycerate kinase activity
CLI14_RS12140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CLI14_RS12145	COG4771	TonB-dependent receptor
CLI14_RS12150	COG0583	DNA-binding transcription factor activity
CLI14_RS12155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLI14_RS12160	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CLI14_RS12165	COG3091	SprT-like family
CLI14_RS12170	COG2356	endonuclease I
CLI14_RS12175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CLI14_RS12185	COG1678	Uncharacterized ACR, COG1678
CLI14_RS12190	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CLI14_RS12205	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLI14_RS12210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLI14_RS12215	COG0762	integral membrane protein
CLI14_RS12220	COG1872	DUF167
CLI14_RS12230	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CLI14_RS12235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLI14_RS12240	COG2066	Belongs to the glutaminase family
CLI14_RS12255	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CLI14_RS12260	COG0741	lytic transglycosylase activity
CLI14_RS12310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CLI14_RS12315	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CLI14_RS12320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLI14_RS12325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CLI14_RS12330	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CLI14_RS12335	COG2967	ApaG domain
CLI14_RS12350	COG3610	response to peptide
CLI14_RS12355	COG2966	Psort location CytoplasmicMembrane, score
CLI14_RS12360	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLI14_RS12365	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CLI14_RS12370	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CLI14_RS12380	COG0142	geranyltranstransferase activity
CLI14_RS12385	COG0531	amino acid
CLI14_RS12395	COG1438	arginine binding
CLI14_RS12405	COG2358	TRAP transporter, solute receptor (TAXI family
CLI14_RS12415	COG0589	response to stress
CLI14_RS12445	COG3550	peptidyl-serine autophosphorylation
CLI14_RS12460	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CLI14_RS12470	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CLI14_RS12515	COG2235	arginine
CLI14_RS12520	COG0312	modulator of DNA gyrase
CLI14_RS12525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLI14_RS12530	COG3164	Protein of unknown function
CLI14_RS12540	COG0424	maF-like protein
CLI14_RS12545	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CLI14_RS12550	COG1792	Involved in formation and maintenance of cell shape
CLI14_RS12555	COG1077	Cell shape determining protein MreB Mrl
CLI14_RS12590	COG2165	general secretion pathway protein
CLI14_RS12600	COG1459	type II secretion system
CLI14_RS12605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLI14_RS12615	COG3267	Type II secretory pathway component ExeA
CLI14_RS12615	COG3409	Peptidoglycan-binding domain 1 protein
CLI14_RS12640	COG2200	EAL domain
CLI14_RS12640	COG2199	diguanylate cyclase activity
CLI14_RS12645	COG0629	single-stranded DNA binding
CLI14_RS12660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CLI14_RS12670	COG2239	Acts as a magnesium transporter
CLI14_RS12685	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CLI14_RS12690	COG0527	aspartate kinase activity
CLI14_RS12695	COG0646	methionine synthase
CLI14_RS12695	COG1410	methionine synthase
CLI14_RS12740	COG0175	sulfate reduction
CLI14_RS12750	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CLI14_RS12770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLI14_RS12775	COG0735	belongs to the Fur family
CLI14_RS12785	COG0166	Belongs to the GPI family
CLI14_RS12790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLI14_RS12805	COG0359	binds to the 23S rRNA
CLI14_RS12815	COG2965	DNA replication, synthesis of RNA primer
CLI14_RS12820	COG0360	Binds together with S18 to 16S ribosomal RNA
CLI14_RS12825	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLI14_RS12830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLI14_RS12835	COG0049	tRNA binding
CLI14_RS12850	COG2923	Belongs to the DsrF TusC family
CLI14_RS12855	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CLI14_RS12860	COG2964	Protein conserved in bacteria
CLI14_RS12865	COG0545	Peptidyl-prolyl cis-trans isomerase
CLI14_RS12880	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CLI14_RS12885	COG0330	HflC and HflK could
CLI14_RS12890	COG0330	HflC and HflK could
CLI14_RS12895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CLI14_RS12905	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CLI14_RS12910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CLI14_RS12920	COG0802	atpase or kinase
CLI14_RS12925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CLI14_RS12975	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CLI14_RS12980	COG1162	GTPase activity
CLI14_RS12990	COG0471	metal ion transport
CLI14_RS12990	COG0490	domain, Protein
CLI14_RS13005	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CLI14_RS13010	COG4942	peptidase
CLI14_RS13025	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CLI14_RS13030	COG2816	NAD+ diphosphatase activity
CLI14_RS13035	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CLI14_RS13040	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLI14_RS13045	COG0085	RNA polymerase activity
CLI14_RS13050	COG0222	ribosome binding
CLI14_RS13055	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CLI14_RS13070	COG0250	Participates in transcription elongation, termination and antitermination
CLI14_RS13075	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CLI14_RS13080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLI14_RS13105	COG1072	(Pantothenic acid kinase))
CLI14_RS13110	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CLI14_RS13110	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CLI14_RS13115	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CLI14_RS13125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLI14_RS13170	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CLI14_RS13185	COG3118	belongs to the thioredoxin family
CLI14_RS13195	COG0248	Ppx GppA phosphatase
CLI14_RS13200	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CLI14_RS13205	COG0194	GDP metabolic process
CLI14_RS13210	COG1758	RNA polymerase activity
CLI14_RS13215	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLI14_RS13220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLI14_RS13225	COG2233	PERMEase
CLI14_RS13260	COG0583	DNA-binding transcription factor activity
CLI14_RS13280	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLI14_RS13285	COG2183	response to ionizing radiation
CLI14_RS13295	COG0596	Alpha beta hydrolase
CLI14_RS13300	COG1040	competence protein
CLI14_RS13305	COG0316	Belongs to the HesB IscA family
CLI14_RS13305	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CLI14_RS13310	COG0494	nUDIX hydrolase
CLI14_RS13315	COG1218	3'(2'),5'-bisphosphate nucleotidase
CLI14_RS13325	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CLI14_RS13330	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CLI14_RS13335	COG3156	type II secretion system protein K
CLI14_RS13340	COG4795	General secretion pathway protein
CLI14_RS13345	COG2165	general secretion pathway protein
CLI14_RS13350	COG2165	general secretion pathway protein
CLI14_RS13355	COG2165	general secretion pathway protein
CLI14_RS13360	COG1459	type II secretion system
CLI14_RS13365	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLI14_RS13375	COG3031	protein transport across the cell outer membrane
CLI14_RS13380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CLI14_RS13385	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CLI14_RS13390	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CLI14_RS13400	COG0456	acetyltransferase
CLI14_RS13405	COG1490	D-aminoacyl-tRNA deacylase activity
CLI14_RS13410	COG1295	ribonuclease BN
CLI14_RS13415	COG1217	gtp-binding protein TYPA
CLI14_RS13420	COG0174	glutamine synthetase
CLI14_RS13430	COG3852	Histidine kinase
CLI14_RS13440	COG3300	MHYT domain
CLI14_RS13440	COG5001	Diguanylate cyclase
CLI14_RS13445	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CLI14_RS13520	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CLI14_RS13565	COG3550	peptidyl-serine autophosphorylation
CLI14_RS13605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CLI14_RS13640	COG3250	beta-galactosidase activity
CLI14_RS13660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLI14_RS13665	COG0534	Mate efflux family protein
CLI14_RS13675	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CLI14_RS13680	COG2937	Belongs to the GPAT DAPAT family
CLI14_RS13690	COG3161	chorismate lyase activity
CLI14_RS13695	COG1580	Controls the rotational direction of flagella during chemotaxis
CLI14_RS13700	COG0705	Rhomboid family
CLI14_RS13710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLI14_RS13715	COG2177	Part of the ABC transporter FtsEX involved in
CLI14_RS13720	COG2884	Cell division ATP-binding protein ftsE
CLI14_RS13725	COG0552	protein localization to endoplasmic reticulum
CLI14_RS13730	COG0742	ribosomal rna small subunit methyltransferase
CLI14_RS13740	COG2095	MarC family integral membrane protein
CLI14_RS13775	COG2433	Pfam Transposase IS66
CLI14_RS13790	COG2095	MarC family integral membrane protein
CLI14_RS13820	COG0783	Belongs to the Dps family
CLI14_RS13825	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CLI14_RS13830	COG1280	lysine exporter protein (LysE YggA)
CLI14_RS13835	COG2267	carboxylic ester hydrolase activity
CLI14_RS13840	COG0561	phosphatase activity
CLI14_RS13850	COG3148	PFAM DTW domain containing protein
CLI14_RS13855	COG1011	Hydrolase
CLI14_RS13860	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CLI14_RS13870	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CLI14_RS13875	COG0019	diaminopimelate decarboxylase activity
CLI14_RS13900	COG1587	Uroporphyrinogen-III synthase
CLI14_RS13905	COG2959	enzyme of heme biosynthesis
CLI14_RS13910	COG3071	HemY protein
CLI14_RS13945	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CLI14_RS13955	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLI14_RS13960	COG0408	coproporphyrinogen oxidase activity
CLI14_RS13965	COG0009	L-threonylcarbamoyladenylate synthase
CLI14_RS13970	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CLI14_RS13975	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CLI14_RS13980	COG0551	DNA topoisomerase type I activity
CLI14_RS13985	COG2922	Belongs to the Smg family
CLI14_RS13990	COG0758	DNA mediated transformation
CLI14_RS13995	COG1652	LysM domain
CLI14_RS14000	COG0242	peptide deformylase activity
CLI14_RS14005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLI14_RS14010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLI14_RS14010	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CLI14_RS14015	COG0569	domain protein
CLI14_RS14020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CLI14_RS14030	COG1272	protein, Hemolysin III
CLI14_RS14040	COG3084	Protein conserved in bacteria
CLI14_RS14055	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CLI14_RS14060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLI14_RS14070	COG2433	Pfam Transposase IS66
CLI14_RS14090	COG2433	Pfam Transposase IS66
CLI14_RS14110	COG2433	Pfam Transposase IS66
CLI14_RS14180	COG0606	chelatase, subunit chli
CLI14_RS14190	COG3978	acetolactate synthase activity
CLI14_RS14195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLI14_RS14210	COG0604	alcohol dehydrogenase
CLI14_RS14225	COG0425	Belongs to the sulfur carrier protein TusA family
CLI14_RS14235	COG2119	membrane
CLI14_RS14240	COG0752	glycyl-tRNA synthetase alpha subunit
CLI14_RS14250	COG3977	Valine--pyruvate aminotransferase
CLI14_RS14255	COG0071	Belongs to the small heat shock protein (HSP20) family
CLI14_RS14270	COG0187	DNA topoisomerase II activity
CLI14_RS14275	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLI14_RS14280	COG0592	DNA-directed DNA polymerase activity
CLI14_RS14300	COG1126	abc transporter atp-binding protein
CLI14_RS14320	COG0706	membrane insertase activity
CLI14_RS14330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CLI14_RS14355	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CLI14_RS14360	COG1444	tRNA N-acetyltransferase activity
CLI14_RS14370	COG0745	RESPONSE REGULATOR receiver
CLI14_RS14375	COG0643	Histidine kinase
CLI14_RS14375	COG2198	Histidine kinase
CLI14_RS14380	COG0835	chemotaxis
CLI14_RS14390	COG0840	transmembrane signaling receptor activity
CLI14_RS14395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLI14_RS14400	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CLI14_RS14450	COG0259	pyridoxamine-phosphate oxidase activity
CLI14_RS14460	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CLI14_RS14515	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLI14_RS14540	COG2909	trisaccharide binding
CLI14_RS14545	COG0058	SHG alpha-glucan phosphorylase activity
CLI14_RS14550	COG1640	4-alpha-glucanotransferase
CLI14_RS14555	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CLI14_RS14565	COG3501	Rhs element vgr protein
CLI14_RS14565	COG3409	Peptidoglycan-binding domain 1 protein
CLI14_RS14595	COG0583	DNA-binding transcription factor activity
CLI14_RS14605	COG0363	glucosamine-6-phosphate deaminase activity
CLI14_RS14610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CLI14_RS14620	COG1067	ATP-dependent peptidase activity
CLI14_RS14630	COG2211	Major facilitator Superfamily
CLI14_RS14650	COG4580	involved in the transport of maltose and maltodextrins
CLI14_RS14655	COG1609	Transcriptional regulator
CLI14_RS14670	COG0395	ABC-type sugar transport system, permease component
CLI14_RS14675	COG3842	ATPase activity
CLI14_RS14680	COG1472	Belongs to the glycosyl hydrolase 3 family
CLI14_RS14685	COG1609	Transcriptional regulator
CLI14_RS14690	COG0840	transmembrane signaling receptor activity
CLI14_RS14700	COG0840	transmembrane signaling receptor activity
CLI14_RS14725	COG3122	Protein conserved in bacteria
CLI14_RS14730	COG1881	PFAM PEBP family protein
CLI14_RS14750	COG1620	l-lactate permease
CLI14_RS14755	COG0583	DNA-binding transcription factor activity
CLI14_RS14780	COG3527	Alpha-acetolactate decarboxylase
CLI14_RS14790	COG0584	glycerophosphoryl diester phosphodiesterase
CLI14_RS14795	COG2271	Major facilitator Superfamily
CLI14_RS14810	COG3047	cAMP biosynthetic process
CLI14_RS14830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLI14_RS14835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLI14_RS14845	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CLI14_RS14850	COG0573	inorganic phosphate transmembrane transporter activity
CLI14_RS14855	COG0581	inorganic phosphate transmembrane transporter activity
CLI14_RS14860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLI14_RS14875	COG3314	Sporulation integral membrane protein YlbJ
CLI14_RS14880	COG0659	secondary active sulfate transmembrane transporter activity
CLI14_RS14890	COG0739	heme binding
CLI14_RS14895	COG5001	Diguanylate cyclase
CLI14_RS14900	COG0583	DNA-binding transcription factor activity
CLI14_RS14905	COG2814	Major facilitator Superfamily
CLI14_RS14925	COG0697	spore germination
CLI14_RS14935	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLI14_RS14955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLI14_RS14960	COG0765	amino acid transport
CLI14_RS14965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI14_RS14970	COG0765	amino acid transport
CLI14_RS14980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLI14_RS14990	COG3123	guanosine phosphorylase activity
CLI14_RS15000	COG1741	Belongs to the pirin family
CLI14_RS15010	COG5001	Diguanylate cyclase
CLI14_RS15045	COG3706	GGDEF domain
CLI14_RS15050	COG2315	Protein conserved in bacteria
CLI14_RS15055	COG0784	Response regulator, receiver
CLI14_RS15055	COG0835	chemotaxis
CLI14_RS15060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLI14_RS15070	COG3842	ATPase activity
CLI14_RS15080	COG1175	transmembrane transport
CLI14_RS15085	COG3833	ABC-type maltose transport systems, permease component
CLI14_RS15110	COG1349	DNA-binding transcription factor activity
CLI14_RS15115	COG2199	diguanylate cyclase activity
CLI14_RS15140	COG2197	response regulator
CLI14_RS15170	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CLI14_RS15175	COG2354	Protein conserved in bacteria
CLI14_RS15180	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLI14_RS15185	COG0418	dihydroorotase activity
CLI14_RS15190	COG3217	Mosc domain protein beta barrel domain protein
CLI14_RS15190	COG0633	Ferredoxin
CLI14_RS15195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLI14_RS15200	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLI14_RS15210	COG3604	Transcriptional regulator
CLI14_RS15220	COG4681	YaeQ
CLI14_RS15225	COG1278	Cold shock
CLI14_RS15250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLI14_RS15255	COG0516	GMP reductase activity
CLI14_RS15270	COG0589	response to stress
CLI14_RS15275	COG0659	secondary active sulfate transmembrane transporter activity
CLI14_RS15285	COG0798	PFAM Bile acid sodium symporter
CLI14_RS15290	COG0640	Transcriptional regulator
CLI14_RS15295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CLI14_RS15315	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CLI14_RS15320	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CLI14_RS15330	COG2271	Major facilitator Superfamily
CLI14_RS15335	COG3851	Histidine kinase
CLI14_RS15340	COG2197	response regulator
CLI14_RS15355	COG0346	lactoylglutathione lyase activity
CLI14_RS15365	COG0156	8-amino-7-oxononanoate synthase activity
CLI14_RS15370	COG1063	alcohol dehydrogenase
CLI14_RS15375	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CLI14_RS15385	COG1368	sulfuric ester hydrolase activity
CLI14_RS15390	COG3530	Putative quorum-sensing-regulated virulence factor
CLI14_RS15405	COG3706	GGDEF domain
CLI14_RS15420	COG2304	oxidoreductase activity
CLI14_RS15440	COG0714	Associated with various cellular activities
CLI14_RS15460	COG0366	Alpha amylase catalytic
CLI14_RS15495	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CLI14_RS15500	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CLI14_RS15510	COG0456	acetyltransferase
CLI14_RS15515	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLI14_RS15520	COG0662	Cupin 2, conserved barrel domain protein
CLI14_RS15525	COG0527	aspartate kinase activity
CLI14_RS15545	COG2113	Glycine betaine
CLI14_RS15550	COG4176	ABC-type proline glycine betaine transport system permease component
CLI14_RS15565	COG1166	arginine decarboxylase activity
CLI14_RS15570	COG0010	Belongs to the arginase family
CLI14_RS15590	COG3300	MHYT domain
CLI14_RS15590	COG5001	Diguanylate cyclase
CLI14_RS15595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLI14_RS15640	COG0484	heat shock protein binding
CLI14_RS15650	COG5001	Diguanylate cyclase
CLI14_RS15650	COG1716	ATPase activity
CLI14_RS15655	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CLI14_RS15665	COG4181	ATPase activity
CLI14_RS15670	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CLI14_RS15680	COG1984	allophanate hydrolase subunit 2
CLI14_RS15690	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CLI14_RS15695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLI14_RS15705	COG0814	amino acid
CLI14_RS15710	COG0513	Belongs to the DEAD box helicase family
CLI14_RS15720	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CLI14_RS15735	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CLI14_RS15750	COG4175	Glycine betaine
CLI14_RS15750	COG0517	IMP dehydrogenase activity
CLI14_RS15755	COG4176	ABC-type proline glycine betaine transport system permease component
CLI14_RS15785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLI14_RS15805	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLI14_RS15825	COG3118	belongs to the thioredoxin family
CLI14_RS15830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLI14_RS15835	COG0247	lactate metabolic process
CLI14_RS15840	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CLI14_RS15845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CLI14_RS15850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CLI14_RS15855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLI14_RS15875	COG3132	Protein of unknown function, DUF480
CLI14_RS15880	COG2827	Endonuclease containing a URI domain
CLI14_RS15895	COG0784	Response regulator, receiver
CLI14_RS15895	COG5002	protein histidine kinase activity
CLI14_RS15925	COG1289	transmembrane transporter activity
CLI14_RS15930	COG0210	DNA helicase
CLI14_RS15935	COG1803	Methylglyoxal synthase
CLI14_RS15940	COG1879	ABC-type sugar transport system periplasmic component
CLI14_RS15945	COG2205	protein histidine kinase activity
CLI14_RS15945	COG2198	Histidine kinase
CLI14_RS15945	COG0784	Response regulator, receiver
CLI14_RS15950	COG0469	pyruvate kinase activity
CLI14_RS15955	COG2271	Major facilitator Superfamily
CLI14_RS15980	COG1979	alcohol dehydrogenase
CLI14_RS15985	COG2207	Transcriptional regulator
CLI14_RS15995	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CLI14_RS16010	COG3111	PFAM Bacterial OB fold (BOF) protein
CLI14_RS16015	COG1492	cobalamin metabolic process
CLI14_RS16020	COG0725	ABC transporter, periplasmic molybdate-binding protein
CLI14_RS16025	COG4149	molybdate abc transporter
CLI14_RS16030	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CLI14_RS16040	COG4251	negative regulation of phosphorylation
CLI14_RS16040	COG5001	Diguanylate cyclase
CLI14_RS16040	COG3706	GGDEF domain
CLI14_RS16040	COG2203	Gaf domain
CLI14_RS16055	COG3437	response regulator, receiver
CLI14_RS16065	COG3852	Histidine kinase
CLI14_RS16070	COG4191	Histidine kinase
CLI14_RS16075	COG5001	Diguanylate cyclase
CLI14_RS16075	COG3300	MHYT domain
CLI14_RS16120	COG3706	GGDEF domain
CLI14_RS16125	COG1328	CTP reductase activity
CLI14_RS16130	COG0602	queuosine metabolic process
CLI14_RS16140	COG0189	ligase activity
CLI14_RS16140	COG4067	protein conserved in archaea
CLI14_RS16155	COG4166	transmembrane transport
CLI14_RS16160	COG4174	ABC transporter (Permease)
CLI14_RS16165	COG4239	(ABC) transporter, permease
CLI14_RS16170	COG4172	Belongs to the ABC transporter superfamily
CLI14_RS16175	COG2203	Gaf domain
CLI14_RS16175	COG3706	GGDEF domain
CLI14_RS16175	COG4251	negative regulation of phosphorylation
CLI14_RS16175	COG5001	Diguanylate cyclase
CLI14_RS16185	COG3038	cytochrome b561
CLI14_RS16190	COG2353	YceI-like domain
CLI14_RS16195	COG0840	transmembrane signaling receptor activity
CLI14_RS16200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLI14_RS16205	COG0545	Peptidyl-prolyl cis-trans isomerase
CLI14_RS16220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLI14_RS16240	COG2897	thiosulfate sulfurtransferase activity
CLI14_RS16245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CLI14_RS16250	COG0303	'Molybdopterin
CLI14_RS16255	COG0302	gtp cyclohydrolase
CLI14_RS16260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLI14_RS16260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLI14_RS16265	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CLI14_RS16270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLI14_RS16275	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CLI14_RS16285	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CLI14_RS16290	COG1011	Hydrolase
CLI14_RS16295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLI14_RS16300	COG2188	Transcriptional regulator
CLI14_RS16310	COG3104	oligopeptide transport
CLI14_RS16320	COG2116	formate transmembrane transporter activity
CLI14_RS16325	COG0583	DNA-binding transcription factor activity
CLI14_RS16335	COG3593	DNA synthesis involved in DNA repair
CLI14_RS16340	COG0737	Belongs to the 5'-nucleotidase family
CLI14_RS16345	COG0861	Integral membrane protein TerC family
CLI14_RS16350	COG2433	Pfam Transposase IS66
CLI14_RS16390	COG2433	Pfam Transposase IS66
CLI14_RS16425	COG2433	Pfam Transposase IS66
CLI14_RS16655	COG3040	lipid binding
CLI14_RS16725	COG2433	Pfam Transposase IS66
CLI14_RS16755	COG0724	RNA recognition motif
CLI14_RS16885	COG0023	Translation Initiation Factor
CLI14_RS16900	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLI14_RS16910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLI14_RS16910	COG1042	CoA-binding domain protein
CLI14_RS16910	COG0045	succinate-CoA ligase (ADP-forming) activity
CLI14_RS16915	COG0583	DNA-binding transcription factor activity
CLI14_RS16935	COG2433	Pfam Transposase IS66
CLI14_RS17035	COG2433	Pfam Transposase IS66
CLI14_RS17205	COG2433	Pfam Transposase IS66
CLI14_RS17220	COG0500	methyltransferase
CLI14_RS17225	COG1187	pseudouridine synthase activity
CLI14_RS17240	COG2433	Pfam Transposase IS66
CLI14_RS17270	COG0513	Belongs to the DEAD box helicase family
CLI14_RS17275	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CLI14_RS17285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CLI14_RS17310	COG3069	C4-dicarboxylate transmembrane transporter activity
CLI14_RS17315	COG2197	response regulator
CLI14_RS17320	COG3850	Histidine kinase
CLI14_RS17325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLI14_RS17335	COG0243	molybdopterin cofactor binding
CLI14_RS17345	COG3005	denitrification pathway
CLI14_RS17355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLI14_RS17360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLI14_RS17385	COG3833	ABC-type maltose transport systems, permease component
CLI14_RS17390	COG1175	transmembrane transport
CLI14_RS17395	COG2182	Extracellular solute-binding protein
CLI14_RS17405	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLI14_RS17415	COG3842	ATPase activity
CLI14_RS17430	COG3730	PTS system glucitol sorbitol-specific
CLI14_RS17435	COG1349	DNA-binding transcription factor activity
CLI14_RS17440	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_RS17445	COG1028	Short-chain dehydrogenase reductase Sdr
CLI14_RS17460	COG3730	PTS system glucitol sorbitol-specific
CLI14_RS17480	COG3675	Pfam Lipase (class 3)
CLI14_RS17490	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CLI14_RS17505	COG0577	efflux transmembrane transporter activity
CLI14_RS17505	COG1136	(ABC) transporter
CLI14_RS17515	COG1136	(ABC) transporter
CLI14_RS17520	COG0523	cobalamin synthesis protein
CLI14_RS17535	COG0156	8-amino-7-oxononanoate synthase activity
CLI14_RS17540	COG0784	Response regulator, receiver
CLI14_RS17540	COG2205	protein histidine kinase activity
CLI14_RS17545	COG0419	ATPase involved in DNA repair
CLI14_RS17550	COG0420	3'-5' exonuclease activity
CLI14_RS17555	COG1609	Transcriptional regulator
CLI14_RS17560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_RS17560	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_RS17565	COG1105	Belongs to the carbohydrate kinase PfkB family
CLI14_RS17570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLI14_RS17570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLI14_RS17570	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CLI14_RS17585	COG0612	Peptidase, M16
CLI14_RS17600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CLI14_RS17610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CLI14_RS17615	COG0509	glycine decarboxylation via glycine cleavage system
CLI14_RS17635	COG1566	PFAM secretion protein HlyD family protein
CLI14_RS17660	COG0656	L-ascorbic acid biosynthetic process
CLI14_RS17665	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLI14_RS17675	COG0861	Integral membrane protein TerC family
CLI14_RS17685	COG2226	methyltransferase
CLI14_RS17695	COG1162	GTPase activity
CLI14_RS17700	COG2433	Pfam Transposase IS66
CLI14_RS17735	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLI14_RS17740	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CLI14_RS17745	COG4604	ABC transporter, ATP-binding protein
CLI14_RS17750	COG4605	iron ion homeostasis
CLI14_RS17755	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLI14_RS17760	COG4607	ABC-type enterochelin transport system periplasmic component
CLI14_RS17790	COG5380	lipid catabolic process
CLI14_RS17795	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CLI14_RS17805	COG3240	lipase activity
CLI14_RS17820	COG0443	Heat shock 70 kDa protein
CLI14_RS17830	COG2814	Major facilitator Superfamily
CLI14_RS17840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLI14_RS17840	COG4191	Histidine kinase
CLI14_RS17845	COG3437	response regulator, receiver
CLI14_RS17845	COG0784	Response regulator, receiver
CLI14_RS17850	COG2207	Transcriptional regulator
CLI14_RS17855	COG0534	Mate efflux family protein
CLI14_RS17860	COG0840	transmembrane signaling receptor activity
CLI14_RS17865	COG2154	pterin-4-alpha-carbinolamine dehydratase
CLI14_RS17870	COG3186	Phenylalanine-4-hydroxylase
CLI14_RS17875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLI14_RS17880	COG0583	DNA-binding transcription factor activity
CLI14_RS17890	COG0583	DNA-binding transcription factor activity
CLI14_RS17905	COG0110	maltose O-acetyltransferase activity
CLI14_RS17910	COG1765	OsmC-like protein
CLI14_RS17915	COG0673	inositol 2-dehydrogenase activity
CLI14_RS17935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLI14_RS17950	COG5002	protein histidine kinase activity
CLI14_RS17950	COG2205	protein histidine kinase activity
CLI14_RS17950	COG0784	Response regulator, receiver
CLI14_RS17960	COG1151	hydroxylamine reductase activity
CLI14_RS17975	COG0531	amino acid
CLI14_RS17985	COG4999	Histidine kinase
CLI14_RS17985	COG3850	Histidine kinase
CLI14_RS17985	COG2205	protein histidine kinase activity
CLI14_RS17985	COG3437	response regulator, receiver
CLI14_RS17990	COG3437	response regulator, receiver
CLI14_RS18000	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CLI14_RS18010	COG5001	Diguanylate cyclase
CLI14_RS18010	COG4251	negative regulation of phosphorylation
CLI14_RS18010	COG3706	GGDEF domain
CLI14_RS18010	COG2203	Gaf domain
CLI14_RS18015	COG3279	Response regulator of the LytR AlgR family
CLI14_RS18020	COG0745	RESPONSE REGULATOR receiver
CLI14_RS18020	COG2972	Histidine kinase
CLI14_RS18035	COG4591	ABC-type transport system involved in lipoprotein release permease component
CLI14_RS18040	COG0577	efflux transmembrane transporter activity
CLI14_RS18040	COG1136	(ABC) transporter
CLI14_RS18050	COG4989	oxidoreductase activity
CLI14_RS18055	COG0366	Alpha amylase catalytic
CLI14_RS18065	COG2267	carboxylic ester hydrolase activity
CLI14_RS18070	COG2188	Transcriptional regulator
CLI14_RS18080	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CLI14_RS18095	COG3457	Alanine racemase
CLI14_RS18100	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CLI14_RS18130	COG0513	Belongs to the DEAD box helicase family
CLI14_RS18140	COG1376	ErfK ybiS ycfS ynhG family protein
CLI14_RS18140	COG1388	LysM domain
CLI14_RS18145	COG0415	Belongs to the DNA photolyase family
CLI14_RS18150	COG0789	Transcriptional regulator
CLI14_RS18155	COG3272	Protein of unknown function (DUF1722)
CLI14_RS18160	COG0813	purine-nucleoside phosphorylase activity
CLI14_RS18185	COG1566	PFAM secretion protein HlyD family protein
CLI14_RS18210	COG0786	glutamate:sodium symporter activity
CLI14_RS18230	COG1999	signal sequence binding
CLI14_RS18240	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CLI14_RS18250	COG0366	Alpha amylase catalytic
CLI14_RS18310	COG0561	phosphatase activity
CLI14_RS18315	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CLI14_RS18320	COG3623	hexulose-6-phosphate isomerase
CLI14_RS18340	COG1132	(ABC) transporter
CLI14_RS18350	COG0671	phosphoesterase, PA-phosphatase related
CLI14_RS18390	COG1131	(ABC) transporter
CLI14_RS18395	COG2188	Transcriptional regulator
CLI14_RS18405	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CLI14_RS18465	COG3501	Rhs element vgr protein
CLI14_RS18490	COG3829	transcription factor binding
CLI14_RS18555	COG0564	pseudouridine synthase activity
CLI14_RS18565	COG0745	RESPONSE REGULATOR receiver
CLI14_RS18580	COG1309	transcriptional regulator
CLI14_RS18585	COG2130	NADP-dependent
CLI14_RS18595	COG1328	CTP reductase activity
CLI14_RS18600	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CLI14_RS18610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLI14_RS18615	COG0251	oxidation-reduction process
CLI14_RS18620	COG0513	Belongs to the DEAD box helicase family
CLI14_RS18640	COG1175	transmembrane transport
CLI14_RS18650	COG3842	ATPase activity
CLI14_RS18665	COG1131	(ABC) transporter
CLI14_RS18670	COG0842	Transport permease protein
CLI14_RS18675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLI14_RS18680	COG3046	protein related to deoxyribodipyrimidine photolyase
CLI14_RS18685	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CLI14_RS18695	COG1846	Transcriptional regulator
CLI14_RS18720	COG2259	Doxx family
CLI14_RS18725	COG1301	dicarboxylic acid transport
CLI14_RS18730	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CLI14_RS18740	COG3722	fumarate hydratase activity
CLI14_RS18745	COG0246	Mannitol dehydrogenase
CLI14_RS18750	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLI14_RS18750	COG2213	PTS system mannitol-specific
CLI14_RS18755	COG0739	heme binding
CLI14_RS18765	COG0363	glucosamine-6-phosphate deaminase activity
CLI14_RS18795	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CLI14_RS18800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CLI14_RS18815	COG3304	Inner membrane component domain
CLI14_RS18825	COG2910	NAD(P)H-binding
CLI14_RS18830	COG0583	DNA-binding transcription factor activity
CLI14_RS18870	COG0814	amino acid
CLI14_RS18875	COG2084	Dehydrogenase
CLI14_RS18965	COG4604	ABC transporter, ATP-binding protein
CLI14_RS18970	COG1535	isochorismatase
CLI14_RS18970	COG3433	isochorismatase activity
CLI14_RS18975	COG1021	2,3-dihydroxybenzoate-AMP ligase
CLI14_RS18980	COG1169	isochorismate synthase
CLI14_RS18995	COG2433	Pfam Transposase IS66
CLI14_RS19010	COG3547	Transposase (IS116 IS110 IS902 family)
CLI14_RS19060	COG1028	Short-chain dehydrogenase reductase Sdr
CLI14_RS19075	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLI14_RS19080	COG4605	iron ion homeostasis
CLI14_RS19085	COG4607	ABC-type enterochelin transport system periplasmic component
CLI14_RS19090	COG4774	siderophore transport
CLI14_RS19095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLI14_RS19125	COG0076	glutamate decarboxylase activity
CLI14_RS19150	COG2433	Pfam Transposase IS66
CLI14_RS19175	COG3657	addiction module killer protein
CLI14_RS19200	COG1192	Involved in chromosome partitioning