locus-tag	class	description
CEQ50_RS00005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEQ50_RS00020	COG1395	domain, Protein
CEQ50_RS00095	COG4974	Belongs to the 'phage' integrase family
CEQ50_RS00105	COG0706	membrane insertase activity
CEQ50_RS00125	COG1126	abc transporter atp-binding protein
CEQ50_RS00145	COG0592	DNA-directed DNA polymerase activity
CEQ50_RS00150	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEQ50_RS00155	COG0187	DNA topoisomerase II activity
CEQ50_RS00170	COG0071	Belongs to the small heat shock protein (HSP20) family
CEQ50_RS00175	COG3977	Valine--pyruvate aminotransferase
CEQ50_RS00185	COG0752	glycyl-tRNA synthetase alpha subunit
CEQ50_RS00190	COG2119	membrane
CEQ50_RS00200	COG0425	Belongs to the sulfur carrier protein TusA family
CEQ50_RS00215	COG0604	alcohol dehydrogenase
CEQ50_RS00230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEQ50_RS00235	COG3978	acetolactate synthase activity
CEQ50_RS00245	COG0606	chelatase, subunit chli
CEQ50_RS00285	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CEQ50_RS00290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEQ50_RS00295	COG4107	phosphonate C-P lyase system protein PhnK
CEQ50_RS00300	COG3627	carbon phosphorus lyase activity
CEQ50_RS00305	COG3626	phosphonate metabolism
CEQ50_RS00325	COG1120	ATPase activity
CEQ50_RS00330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ50_RS00335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEQ50_RS00340	COG0583	DNA-binding transcription factor activity
CEQ50_RS00345	COG0606	chelatase, subunit chli
CEQ50_RS00355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEQ50_RS00360	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CEQ50_RS00375	COG3084	Protein conserved in bacteria
CEQ50_RS00385	COG1272	protein, Hemolysin III
CEQ50_RS00395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEQ50_RS00400	COG0569	domain protein
CEQ50_RS00405	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEQ50_RS00405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEQ50_RS00410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEQ50_RS00415	COG0242	peptide deformylase activity
CEQ50_RS00420	COG1652	LysM domain
CEQ50_RS00425	COG0758	DNA mediated transformation
CEQ50_RS00430	COG2922	Belongs to the Smg family
CEQ50_RS00435	COG0551	DNA topoisomerase type I activity
CEQ50_RS00440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CEQ50_RS00445	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CEQ50_RS00450	COG0009	L-threonylcarbamoyladenylate synthase
CEQ50_RS00455	COG0408	coproporphyrinogen oxidase activity
CEQ50_RS00460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEQ50_RS00470	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CEQ50_RS00505	COG3071	HemY protein
CEQ50_RS00510	COG2959	enzyme of heme biosynthesis
CEQ50_RS00515	COG1587	Uroporphyrinogen-III synthase
CEQ50_RS00540	COG0019	diaminopimelate decarboxylase activity
CEQ50_RS00545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CEQ50_RS00555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CEQ50_RS00560	COG1011	Hydrolase
CEQ50_RS00565	COG3148	PFAM DTW domain containing protein
CEQ50_RS00575	COG0561	phosphatase activity
CEQ50_RS00580	COG2267	carboxylic ester hydrolase activity
CEQ50_RS00585	COG1280	lysine exporter protein (LysE YggA)
CEQ50_RS00590	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CEQ50_RS00595	COG0783	Belongs to the Dps family
CEQ50_RS00625	COG2095	MarC family integral membrane protein
CEQ50_RS00635	COG0742	ribosomal rna small subunit methyltransferase
CEQ50_RS00640	COG0552	protein localization to endoplasmic reticulum
CEQ50_RS00645	COG2884	Cell division ATP-binding protein ftsE
CEQ50_RS00650	COG2177	Part of the ABC transporter FtsEX involved in
CEQ50_RS00655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEQ50_RS00665	COG0705	Rhomboid family
CEQ50_RS00670	COG1580	Controls the rotational direction of flagella during chemotaxis
CEQ50_RS00675	COG3161	chorismate lyase activity
CEQ50_RS00685	COG2937	Belongs to the GPAT DAPAT family
CEQ50_RS00690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CEQ50_RS00700	COG0534	Mate efflux family protein
CEQ50_RS00705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ50_RS00720	COG3250	beta-galactosidase activity
CEQ50_RS00750	COG0848	biopolymer transport protein
CEQ50_RS00755	COG0811	peptide transport
CEQ50_RS00760	COG0811	peptide transport
CEQ50_RS00770	COG4771	TonB-dependent receptor
CEQ50_RS00775	COG4178	(ABC) transporter
CEQ50_RS00780	COG0612	Peptidase, M16
CEQ50_RS00800	COG2003	Belongs to the UPF0758 family
CEQ50_RS00815	COG3339	Conserved Protein
CEQ50_RS00895	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CEQ50_RS00905	COG3344	reverse transcriptase
CEQ50_RS00935	COG2433	Pfam Transposase IS66
CEQ50_RS00945	COG2194	sulfuric ester hydrolase activity
CEQ50_RS00950	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEQ50_RS00970	COG2433	Pfam Transposase IS66
CEQ50_RS00990	COG3550	peptidyl-serine autophosphorylation
CEQ50_RS01015	COG4206	TonB-dependent receptor
CEQ50_RS01025	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEQ50_RS01060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CEQ50_RS01065	COG3300	MHYT domain
CEQ50_RS01065	COG5001	Diguanylate cyclase
CEQ50_RS01075	COG3852	Histidine kinase
CEQ50_RS01085	COG0174	glutamine synthetase
CEQ50_RS01090	COG1217	gtp-binding protein TYPA
CEQ50_RS01095	COG1295	ribonuclease BN
CEQ50_RS01100	COG1490	D-aminoacyl-tRNA deacylase activity
CEQ50_RS01105	COG0456	acetyltransferase
CEQ50_RS01115	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CEQ50_RS01120	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEQ50_RS01125	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEQ50_RS01130	COG3031	protein transport across the cell outer membrane
CEQ50_RS01140	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEQ50_RS01145	COG1459	type II secretion system
CEQ50_RS01150	COG2165	general secretion pathway protein
CEQ50_RS01155	COG2165	general secretion pathway protein
CEQ50_RS01160	COG2165	general secretion pathway protein
CEQ50_RS01165	COG4795	General secretion pathway protein
CEQ50_RS01170	COG3156	type II secretion system protein K
CEQ50_RS01175	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CEQ50_RS01180	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CEQ50_RS01190	COG1218	3'(2'),5'-bisphosphate nucleotidase
CEQ50_RS01195	COG0494	nUDIX hydrolase
CEQ50_RS01200	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CEQ50_RS01200	COG0316	Belongs to the HesB IscA family
CEQ50_RS01205	COG1040	competence protein
CEQ50_RS01210	COG0596	Alpha beta hydrolase
CEQ50_RS01220	COG2183	response to ionizing radiation
CEQ50_RS01225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEQ50_RS01245	COG0583	DNA-binding transcription factor activity
CEQ50_RS01280	COG2233	PERMEase
CEQ50_RS01285	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEQ50_RS01290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEQ50_RS01295	COG1758	RNA polymerase activity
CEQ50_RS01300	COG0194	GDP metabolic process
CEQ50_RS01305	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CEQ50_RS01315	COG0248	Ppx GppA phosphatase
CEQ50_RS01325	COG3118	belongs to the thioredoxin family
CEQ50_RS01340	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CEQ50_RS01400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEQ50_RS01410	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEQ50_RS01415	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CEQ50_RS01415	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CEQ50_RS01420	COG1072	(Pantothenic acid kinase))
CEQ50_RS01445	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEQ50_RS01450	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEQ50_RS01455	COG0250	Participates in transcription elongation, termination and antitermination
CEQ50_RS01470	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEQ50_RS01475	COG0222	ribosome binding
CEQ50_RS01480	COG0085	RNA polymerase activity
CEQ50_RS01485	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEQ50_RS01490	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CEQ50_RS01495	COG2816	NAD+ diphosphatase activity
CEQ50_RS01500	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CEQ50_RS01515	COG4942	peptidase
CEQ50_RS01520	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CEQ50_RS01535	COG0471	metal ion transport
CEQ50_RS01535	COG0490	domain, Protein
CEQ50_RS01545	COG1162	GTPase activity
CEQ50_RS01550	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CEQ50_RS01600	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEQ50_RS01605	COG0802	atpase or kinase
CEQ50_RS01615	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEQ50_RS01630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEQ50_RS01635	COG0330	HflC and HflK could
CEQ50_RS01640	COG0330	HflC and HflK could
CEQ50_RS01645	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CEQ50_RS01660	COG0545	Peptidyl-prolyl cis-trans isomerase
CEQ50_RS01665	COG2964	Protein conserved in bacteria
CEQ50_RS01670	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CEQ50_RS01675	COG2923	Belongs to the DsrF TusC family
CEQ50_RS01690	COG0049	tRNA binding
CEQ50_RS01695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEQ50_RS01700	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEQ50_RS01705	COG0360	Binds together with S18 to 16S ribosomal RNA
CEQ50_RS01710	COG2965	DNA replication, synthesis of RNA primer
CEQ50_RS01720	COG0359	binds to the 23S rRNA
CEQ50_RS01735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEQ50_RS01740	COG0166	Belongs to the GPI family
CEQ50_RS01750	COG0735	belongs to the Fur family
CEQ50_RS01755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEQ50_RS01775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEQ50_RS01785	COG0175	sulfate reduction
CEQ50_RS01870	COG1410	methionine synthase
CEQ50_RS01870	COG0646	methionine synthase
CEQ50_RS01875	COG0527	aspartate kinase activity
CEQ50_RS01880	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CEQ50_RS01895	COG2239	Acts as a magnesium transporter
CEQ50_RS01905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEQ50_RS01945	COG2433	Pfam Transposase IS66
CEQ50_RS01960	COG2433	Pfam Transposase IS66
CEQ50_RS02015	COG0629	single-stranded DNA binding
CEQ50_RS02020	COG2199	diguanylate cyclase activity
CEQ50_RS02020	COG2200	EAL domain
CEQ50_RS02045	COG3409	Peptidoglycan-binding domain 1 protein
CEQ50_RS02045	COG3267	Type II secretory pathway component ExeA
CEQ50_RS02055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEQ50_RS02060	COG1459	type II secretion system
CEQ50_RS02070	COG2165	general secretion pathway protein
CEQ50_RS02075	COG2165	general secretion pathway protein
CEQ50_RS02105	COG1077	Cell shape determining protein MreB Mrl
CEQ50_RS02110	COG1792	Involved in formation and maintenance of cell shape
CEQ50_RS02115	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CEQ50_RS02120	COG0424	maF-like protein
CEQ50_RS02130	COG3164	Protein of unknown function
CEQ50_RS02135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEQ50_RS02140	COG0312	modulator of DNA gyrase
CEQ50_RS02155	COG2433	Pfam Transposase IS66
CEQ50_RS02165	COG2235	arginine
CEQ50_RS02185	COG0589	response to stress
CEQ50_RS02195	COG2358	TRAP transporter, solute receptor (TAXI family
CEQ50_RS02205	COG1438	arginine binding
CEQ50_RS02215	COG0531	amino acid
CEQ50_RS02220	COG0142	geranyltranstransferase activity
CEQ50_RS02230	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CEQ50_RS02235	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEQ50_RS02240	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEQ50_RS02245	COG2966	Psort location CytoplasmicMembrane, score
CEQ50_RS02250	COG3610	response to peptide
CEQ50_RS02265	COG2967	ApaG domain
CEQ50_RS02270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CEQ50_RS02275	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CEQ50_RS02280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEQ50_RS02285	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CEQ50_RS02290	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CEQ50_RS02340	COG0741	lytic transglycosylase activity
CEQ50_RS02345	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CEQ50_RS02360	COG2066	Belongs to the glutaminase family
CEQ50_RS02365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEQ50_RS02370	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CEQ50_RS02380	COG1872	DUF167
CEQ50_RS02385	COG0762	integral membrane protein
CEQ50_RS02390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CEQ50_RS02395	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CEQ50_RS02410	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CEQ50_RS02415	COG1678	Uncharacterized ACR, COG1678
CEQ50_RS02425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEQ50_RS02430	COG2356	endonuclease I
CEQ50_RS02435	COG3091	SprT-like family
CEQ50_RS02440	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEQ50_RS02445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEQ50_RS02450	COG0583	DNA-binding transcription factor activity
CEQ50_RS02455	COG4771	TonB-dependent receptor
CEQ50_RS02460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEQ50_RS02465	COG0126	phosphoglycerate kinase activity
CEQ50_RS02475	COG0191	fructose-bisphosphate aldolase activity
CEQ50_RS02480	COG0668	transmembrane transport
CEQ50_RS02500	COG3706	GGDEF domain
CEQ50_RS02510	COG1349	DNA-binding transcription factor activity
CEQ50_RS02535	COG3501	Rhs element vgr protein
CEQ50_RS02570	COG2378	regulation of single-species biofilm formation
CEQ50_RS02650	COG2433	Pfam Transposase IS66
CEQ50_RS02705	COG1610	YqeY-like protein
CEQ50_RS02710	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CEQ50_RS02715	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CEQ50_RS02725	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CEQ50_RS02730	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CEQ50_RS02735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEQ50_RS02740	COG1968	undecaprenyl-diphosphatase activity
CEQ50_RS02745	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CEQ50_RS02750	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CEQ50_RS02755	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CEQ50_RS02760	COG0585	pseudouridine synthase activity
CEQ50_RS02765	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CEQ50_RS02770	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CEQ50_RS02775	COG1388	LysM domain
CEQ50_RS02775	COG4942	peptidase
CEQ50_RS02780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEQ50_RS02785	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEQ50_RS02805	COG4208	sulfate ABC transporter
CEQ50_RS02810	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CEQ50_RS02815	COG1546	Belongs to the CinA family
CEQ50_RS02820	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEQ50_RS02825	COG2137	regulation of response to DNA damage stimulus
CEQ50_RS02830	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEQ50_RS02835	COG0527	aspartate kinase activity
CEQ50_RS02840	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CEQ50_RS02885	COG3630	sodium ion export across plasma membrane
CEQ50_RS02890	COG0511	ligase activity, forming carbon-carbon bonds
CEQ50_RS02890	COG5016	pyruvate
CEQ50_RS02895	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CEQ50_RS02905	COG1238	metal cluster binding
CEQ50_RS02910	COG0612	Peptidase, M16
CEQ50_RS02920	COG1854	S-ribosylhomocysteine lyase activity
CEQ50_RS02925	COG4536	flavin adenine dinucleotide binding
CEQ50_RS02930	COG4137	Cytochrome C assembly protein
CEQ50_RS02935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEQ50_RS02940	COG0228	four-way junction DNA binding
CEQ50_RS02945	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CEQ50_RS02950	COG0336	Belongs to the RNA methyltransferase TrmD family
CEQ50_RS02955	COG0335	large ribosomal subunit rRNA binding
CEQ50_RS02965	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CEQ50_RS02970	COG0237	dephospho-CoA kinase activity
CEQ50_RS02980	COG1459	type II secretion system
CEQ50_RS02985	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEQ50_RS02995	COG0157	Belongs to the NadC ModD family
CEQ50_RS03005	COG0716	FMN binding
CEQ50_RS03010	COG4974	Belongs to the 'phage' integrase family
CEQ50_RS03015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEQ50_RS03020	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CEQ50_RS03025	COG2186	Transcriptional regulator
CEQ50_RS03030	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CEQ50_RS03035	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEQ50_RS03040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ50_RS03055	COG0288	reversible hydration of carbon dioxide
CEQ50_RS03060	COG0659	secondary active sulfate transmembrane transporter activity
CEQ50_RS03065	COG1131	(ABC) transporter
CEQ50_RS03070	COG0842	Transport permease protein
CEQ50_RS03080	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CEQ50_RS03090	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEQ50_RS03100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEQ50_RS03105	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CEQ50_RS03110	COG1489	DNA binding
CEQ50_RS03115	COG1643	Atp-dependent helicase
CEQ50_RS03120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEQ50_RS03125	COG1752	Esterase of the alpha-beta hydrolase superfamily
CEQ50_RS03130	COG1049	propionate catabolic process, 2-methylcitrate cycle
CEQ50_RS03135	COG1929	Belongs to the glycerate kinase type-1 family
CEQ50_RS03140	COG2610	gluconate transmembrane transporter activity
CEQ50_RS03145	COG3835	regulator
CEQ50_RS03150	COG3112	Uncharacterised protein family (UPF0231)
CEQ50_RS03160	COG0004	ammonium transporteR
CEQ50_RS03165	COG1840	ABC-type Fe3 transport system, periplasmic component
CEQ50_RS03175	COG3842	ATPase activity
CEQ50_RS03180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEQ50_RS03195	COG2971	BadF BadG BcrA BcrD
CEQ50_RS03205	COG4608	Belongs to the ABC transporter superfamily
CEQ50_RS03210	COG0444	Belongs to the ABC transporter superfamily
CEQ50_RS03215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEQ50_RS03230	COG2205	protein histidine kinase activity
CEQ50_RS03230	COG0784	Response regulator, receiver
CEQ50_RS03240	COG0628	permease
CEQ50_RS03245	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEQ50_RS03250	COG0316	Belongs to the HesB IscA family
CEQ50_RS03265	COG0739	heme binding
CEQ50_RS03270	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEQ50_RS03280	COG2239	Acts as a magnesium transporter
CEQ50_RS03285	COG2027	D-alanyl-D-alanine carboxypeptidase
CEQ50_RS03290	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CEQ50_RS03295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEQ50_RS03300	COG1534	Rna-binding protein
CEQ50_RS03305	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CEQ50_RS03310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEQ50_RS03315	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CEQ50_RS03320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEQ50_RS03325	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEQ50_RS03340	COG0779	Required for maturation of 30S ribosomal subunits
CEQ50_RS03345	COG0195	Participates in both transcription termination and antitermination
CEQ50_RS03360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CEQ50_RS03365	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CEQ50_RS03380	COG1846	Transcriptional regulator
CEQ50_RS03390	COG0826	peptidase U32
CEQ50_RS03395	COG0826	peptidase U32
CEQ50_RS03405	COG3154	lipid carrier protein
CEQ50_RS03410	COG3153	acetyltransferase
CEQ50_RS03435	COG0513	Belongs to the DEAD box helicase family
CEQ50_RS03440	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CEQ50_RS03455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CEQ50_RS03465	COG2204	response regulator
CEQ50_RS03475	COG0667	Aldo Keto reductase
CEQ50_RS03485	COG0494	nUDIX hydrolase
CEQ50_RS03490	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CEQ50_RS03495	COG0730	response to heat
CEQ50_RS03505	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEQ50_RS03510	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEQ50_RS03525	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CEQ50_RS03530	COG0732	type I restriction modification DNA specificity domain
CEQ50_RS03535	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CEQ50_RS03550	COG3550	peptidyl-serine autophosphorylation
CEQ50_RS03575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEQ50_RS03595	COG2433	Pfam Transposase IS66
CEQ50_RS03625	COG2433	Pfam Transposase IS66
CEQ50_RS03645	COG2433	Pfam Transposase IS66
CEQ50_RS03655	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEQ50_RS03660	COG1283	sodium-dependent phosphate transmembrane transporter activity
CEQ50_RS03665	COG0583	DNA-binding transcription factor activity
CEQ50_RS03670	COG0640	Transcriptional regulator
CEQ50_RS03675	COG0268	Binds directly to 16S ribosomal RNA
CEQ50_RS03680	COG0728	peptidoglycan biosynthetic process
CEQ50_RS03685	COG0196	riboflavin kinase activity
CEQ50_RS03695	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CEQ50_RS03700	COG1047	Peptidyl-prolyl cis-trans
CEQ50_RS03705	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CEQ50_RS03710	COG1966	Carbon starvation protein
CEQ50_RS03720	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEQ50_RS03725	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CEQ50_RS03735	COG3279	Response regulator of the LytR AlgR family
CEQ50_RS03740	COG3275	phosphorelay sensor kinase activity
CEQ50_RS03745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEQ50_RS03750	COG1605	Chorismate mutase
CEQ50_RS03750	COG0287	Prephenate dehydrogenase
CEQ50_RS03760	COG0488	(ABC) transporter
CEQ50_RS03770	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CEQ50_RS03775	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CEQ50_RS03780	COG5001	Diguanylate cyclase
CEQ50_RS03785	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEQ50_RS03790	COG0077	Prephenate dehydratase
CEQ50_RS03790	COG1605	Chorismate mutase
CEQ50_RS03795	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEQ50_RS03800	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ50_RS03805	COG0564	pseudouridine synthase activity
CEQ50_RS03810	COG1496	oxidoreductase activity
CEQ50_RS03815	COG0542	response to heat
CEQ50_RS03870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEQ50_RS03875	COG0826	peptidase U32
CEQ50_RS03885	COG0745	RESPONSE REGULATOR receiver
CEQ50_RS03890	COG5002	protein histidine kinase activity
CEQ50_RS03900	COG0248	Ppx GppA phosphatase
CEQ50_RS03905	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CEQ50_RS03915	COG0581	inorganic phosphate transmembrane transporter activity
CEQ50_RS03920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEQ50_RS03925	COG0704	Plays a role in the regulation of phosphate uptake
CEQ50_RS03935	COG0450	alkyl hydroperoxide reductase
CEQ50_RS03940	COG0583	DNA-binding transcription factor activity
CEQ50_RS03945	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CEQ50_RS03955	COG0517	IMP dehydrogenase activity
CEQ50_RS03965	COG0343	queuine tRNA-ribosyltransferase activity
CEQ50_RS03970	COG1862	Preprotein translocase
CEQ50_RS03975	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEQ50_RS03980	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEQ50_RS03985	COG0483	inositol monophosphate 1-phosphatase activity
CEQ50_RS03990	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CEQ50_RS03995	COG1959	2 iron, 2 sulfur cluster binding
CEQ50_RS04005	COG0822	iron-sulfur transferase activity
CEQ50_RS04010	COG0316	Belongs to the HesB IscA family
CEQ50_RS04020	COG0443	Heat shock 70 kDa protein
CEQ50_RS04025	COG0633	Ferredoxin
CEQ50_RS04030	COG2975	iron-sulfur cluster assembly
CEQ50_RS04035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEQ50_RS04050	COG1426	Protein conserved in bacteria
CEQ50_RS04055	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CEQ50_RS04060	COG0124	histidyl-tRNA synthetase
CEQ50_RS04065	COG2976	Protein conserved in bacteria
CEQ50_RS04070	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ50_RS04075	COG1160	GTP binding
CEQ50_RS04090	COG0517	IMP dehydrogenase activity
CEQ50_RS04090	COG0516	GMP reductase activity
CEQ50_RS04095	COG0519	Catalyzes the synthesis of GMP from XMP
CEQ50_RS04095	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEQ50_RS04100	COG0351	phosphomethylpyrimidine kinase
CEQ50_RS04110	COG1584	GPR1 FUN34 yaaH family protein
CEQ50_RS04115	COG1115	amino acid carrier protein
CEQ50_RS04140	COG3711	transcriptional antiterminator
CEQ50_RS04140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_RS04155	COG3964	amidohydrolase
CEQ50_RS04185	COG0556	nucleotide-excision repair
CEQ50_RS04320	COG0582	viral genome integration into host DNA
CEQ50_RS04335	COG2867	negative regulation of translational initiation
CEQ50_RS04340	COG2914	Belongs to the UPF0125 (RnfH) family
CEQ50_RS04345	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ50_RS04350	COG0497	DNA recombination
CEQ50_RS04355	COG0251	oxidation-reduction process
CEQ50_RS04360	COG0814	amino acid
CEQ50_RS04365	COG3033	Beta-eliminating lyase
CEQ50_RS04370	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEQ50_RS04375	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEQ50_RS04380	COG0443	Heat shock 70 kDa protein
CEQ50_RS04385	COG0484	heat shock protein binding
CEQ50_RS04415	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CEQ50_RS04420	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CEQ50_RS04430	COG0583	DNA-binding transcription factor activity
CEQ50_RS04435	COG0590	tRNA wobble adenosine to inosine editing
CEQ50_RS04440	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CEQ50_RS04450	COG0047	phosphoribosylformylglycinamidine synthase activity
CEQ50_RS04450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEQ50_RS04470	COG2979	Protein of unknown function (DUF533)
CEQ50_RS04475	COG0442	prolyl-tRNA aminoacylation
CEQ50_RS04480	COG1720	tRNA m6t6A37 methyltransferase activity
CEQ50_RS04485	COG0254	rRNA binding
CEQ50_RS04490	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEQ50_RS04520	COG3098	single-species biofilm formation
CEQ50_RS04525	COG0564	pseudouridine synthase activity
CEQ50_RS04530	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEQ50_RS04535	COG0142	geranyltranstransferase activity
CEQ50_RS04540	COG1722	exodeoxyribonuclease VII activity
CEQ50_RS04545	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CEQ50_RS04555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEQ50_RS04555	COG0301	tRNA thio-modification
CEQ50_RS04560	COG0583	DNA-binding transcription factor activity
CEQ50_RS04565	COG2363	Small membrane protein
CEQ50_RS04570	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CEQ50_RS04575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ50_RS04580	COG1611	Belongs to the LOG family
CEQ50_RS04605	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CEQ50_RS04610	COG1464	Belongs to the NlpA lipoprotein family
CEQ50_RS04615	COG2011	ABC-type metal ion transport system permease component
CEQ50_RS04620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEQ50_RS04625	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEQ50_RS04640	COG1263	PTS System
CEQ50_RS04640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ50_RS04645	COG0366	Alpha amylase catalytic
CEQ50_RS04650	COG0745	RESPONSE REGULATOR receiver
CEQ50_RS04655	COG2205	protein histidine kinase activity
CEQ50_RS04690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ50_RS04695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ50_RS04700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEQ50_RS04705	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CEQ50_RS04710	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CEQ50_RS04715	COG0438	transferase activity, transferring glycosyl groups
CEQ50_RS04720	COG2244	polysaccharide biosynthetic process
CEQ50_RS04730	COG0438	transferase activity, transferring glycosyl groups
CEQ50_RS04760	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CEQ50_RS04805	COG0489	protein tyrosine kinase activity
CEQ50_RS04810	COG1596	polysaccharide export
CEQ50_RS04840	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CEQ50_RS04845	COG0321	lipoyl(octanoyl) transferase activity
CEQ50_RS04850	COG2921	Belongs to the UPF0250 family
CEQ50_RS04855	COG1686	Belongs to the peptidase S11 family
CEQ50_RS04860	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CEQ50_RS04865	COG0772	Belongs to the SEDS family
CEQ50_RS04870	COG0768	penicillin binding
CEQ50_RS04875	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEQ50_RS04880	COG0799	negative regulation of ribosome biogenesis
CEQ50_RS04885	COG1466	dna polymerase III delta subunit
CEQ50_RS04890	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CEQ50_RS04895	COG0495	leucyl-tRNA aminoacylation
CEQ50_RS04900	COG2888	peptidyl-tyrosine sulfation
CEQ50_RS04905	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CEQ50_RS04910	COG4535	Mg2 and Co2 transporter CorC
CEQ50_RS04915	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CEQ50_RS04920	COG1702	phosphate starvation-inducible protein PhoH
CEQ50_RS04925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEQ50_RS04930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEQ50_RS04935	COG2190	(PTS) system
CEQ50_RS04940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEQ50_RS04945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_RS04950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEQ50_RS04955	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CEQ50_RS04960	COG3115	cell septum assembly
CEQ50_RS04965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEQ50_RS04980	COG0789	Transcriptional regulator
CEQ50_RS04990	COG0330	HflC and HflK could
CEQ50_RS04995	COG3118	belongs to the thioredoxin family
CEQ50_RS05000	COG1090	epimerase
CEQ50_RS05005	COG0622	Phosphoesterase
CEQ50_RS05020	COG3710	Transcriptional regulator
CEQ50_RS05025	COG0326	Molecular chaperone. Has ATPase activity
CEQ50_RS05035	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEQ50_RS05040	COG3104	oligopeptide transport
CEQ50_RS05050	COG0367	asparagine synthase
CEQ50_RS05055	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEQ50_RS05055	COG4651	solute:proton antiporter activity
CEQ50_RS05060	COG1846	Transcriptional regulator
CEQ50_RS05060	COG1940	carbohydrate kinase activity
CEQ50_RS05065	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEQ50_RS05070	COG2190	(PTS) system
CEQ50_RS05070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ50_RS05070	COG1263	PTS System
CEQ50_RS05075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEQ50_RS05085	COG0101	tRNA pseudouridine synthase activity
CEQ50_RS05090	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CEQ50_RS05095	COG0285	dihydrofolate synthase activity
CEQ50_RS05100	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CEQ50_RS05105	COG1286	toxin biosynthetic process
CEQ50_RS05110	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CEQ50_RS05115	COG2056	Na+-H+ antiporter family
CEQ50_RS05120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEQ50_RS05130	COG0346	lactoylglutathione lyase activity
CEQ50_RS05135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEQ50_RS05140	COG4660	Part of a membrane complex involved in electron transport
CEQ50_RS05145	COG4659	FMN binding
CEQ50_RS05150	COG4658	electron transport chain
CEQ50_RS05155	COG4656	Part of a membrane complex involved in electron transport
CEQ50_RS05160	COG2878	Part of a membrane complex involved in electron transport
CEQ50_RS05165	COG4657	Part of a membrane complex involved in electron transport
CEQ50_RS05175	COG1629	transport
CEQ50_RS05175	COG4774	siderophore transport
CEQ50_RS05180	COG2382	esterase
CEQ50_RS05200	COG1535	isochorismatase
CEQ50_RS05200	COG3433	isochorismatase activity
CEQ50_RS05205	COG1021	2,3-dihydroxybenzoate-AMP ligase
CEQ50_RS05210	COG1169	isochorismate synthase
CEQ50_RS05215	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ50_RS05220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEQ50_RS05235	COG0556	nucleotide-excision repair
CEQ50_RS05240	COG2204	response regulator
CEQ50_RS05245	COG2198	Histidine kinase
CEQ50_RS05250	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CEQ50_RS05255	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEQ50_RS05260	COG0521	Mo-molybdopterin cofactor biosynthetic process
CEQ50_RS05270	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CEQ50_RS05275	COG0314	molybdopterin synthase activity
CEQ50_RS05280	COG2199	diguanylate cyclase activity
CEQ50_RS05285	COG0617	tRNA 3'-terminal CCA addition
CEQ50_RS05285	COG0517	IMP dehydrogenase activity
CEQ50_RS05285	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CEQ50_RS05295	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CEQ50_RS05305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ50_RS05305	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ50_RS05310	COG0489	protein tyrosine kinase activity
CEQ50_RS05315	COG0572	uridine kinase
CEQ50_RS05320	COG2982	Protein involved in outer membrane biogenesis
CEQ50_RS05325	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CEQ50_RS05330	COG2067	long-chain fatty acid transport protein
CEQ50_RS05335	COG2067	long-chain fatty acid transport protein
CEQ50_RS05345	COG1595	DNA-templated transcription, initiation
CEQ50_RS05355	COG0183	Belongs to the thiolase family
CEQ50_RS05360	COG1024	Enoyl-CoA hydratase
CEQ50_RS05360	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEQ50_RS05365	COG0778	Nitroreductase
CEQ50_RS05370	COG0583	DNA-binding transcription factor activity
CEQ50_RS05375	COG0745	RESPONSE REGULATOR receiver
CEQ50_RS05385	COG2832	Protein of unknown function (DUF454)
CEQ50_RS05390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEQ50_RS05405	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CEQ50_RS05415	COG2983	Belongs to the UPF0260 family
CEQ50_RS05430	COG2226	methyltransferase
CEQ50_RS05445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ50_RS05455	COG3139	Protein of unknown function (DUF1315)
CEQ50_RS05460	COG0252	asparaginase activity
CEQ50_RS05465	COG0616	signal peptide processing
CEQ50_RS05470	COG1902	pentaerythritol trinitrate reductase activity
CEQ50_RS05470	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEQ50_RS05475	COG0788	formyltetrahydrofolate deformylase activity
CEQ50_RS05485	COG1199	ATP-dependent helicase activity
CEQ50_RS05490	COG1214	PFAM Peptidase M22, glycoprotease
CEQ50_RS05505	COG0596	Alpha beta hydrolase
CEQ50_RS05510	COG0318	PFAM AMP-dependent synthetase and ligase
CEQ50_RS05515	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CEQ50_RS05520	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CEQ50_RS05525	COG2894	cell division
CEQ50_RS05535	COG3100	YcgL domain-containing protein
CEQ50_RS05540	COG2951	lytic endotransglycosylase activity
CEQ50_RS05545	COG0583	DNA-binding transcription factor activity
CEQ50_RS05550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEQ50_RS05575	COG4628	conserved protein (DUF2132)
CEQ50_RS05590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEQ50_RS05600	COG0513	Belongs to the DEAD box helicase family
CEQ50_RS05610	COG1760	l-serine dehydratase
CEQ50_RS05615	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CEQ50_RS05630	COG1653	transport
CEQ50_RS05640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEQ50_RS05645	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CEQ50_RS05650	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEQ50_RS05670	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEQ50_RS05680	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CEQ50_RS05685	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CEQ50_RS05690	COG0776	regulation of translation
CEQ50_RS05695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEQ50_RS05700	COG1555	photosystem II stabilization
CEQ50_RS05705	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CEQ50_RS05710	COG0539	negative regulation of cytoplasmic translation
CEQ50_RS05715	COG0776	regulation of translation
CEQ50_RS05720	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CEQ50_RS05725	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CEQ50_RS05740	COG0583	DNA-binding transcription factor activity
CEQ50_RS05750	COG0686	Belongs to the AlaDH PNT family
CEQ50_RS05755	COG1522	sequence-specific DNA binding
CEQ50_RS05760	COG1674	ftsk spoiiie
CEQ50_RS05770	COG0501	Belongs to the peptidase M48B family
CEQ50_RS05780	COG0300	oxidoreductase activity
CEQ50_RS05795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEQ50_RS05805	COG2268	Band 7 protein
CEQ50_RS05815	COG1032	radical SAM domain protein
CEQ50_RS05825	COG2203	Gaf domain
CEQ50_RS05825	COG2199	diguanylate cyclase activity
CEQ50_RS05825	COG2200	EAL domain
CEQ50_RS05840	COG0583	DNA-binding transcription factor activity
CEQ50_RS05845	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEQ50_RS05860	COG2350	Protein conserved in bacteria
CEQ50_RS05890	COG0159	tryptophan synthase activity
CEQ50_RS05895	COG0133	tryptophan synthase activity
CEQ50_RS05900	COG0134	indole-3-glycerol-phosphate synthase activity
CEQ50_RS05900	COG0135	phosphoribosylanthranilate isomerase activity
CEQ50_RS05905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEQ50_RS05910	COG0512	Glutamine amidotransferase of anthranilate synthase
CEQ50_RS05915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CEQ50_RS05925	COG0613	PHP domain protein
CEQ50_RS05930	COG0009	L-threonylcarbamoyladenylate synthase
CEQ50_RS05935	COG1187	pseudouridine synthase activity
CEQ50_RS05945	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CEQ50_RS05950	COG4988	ABC transporter
CEQ50_RS05955	COG0492	ferredoxin-NADP+ reductase activity
CEQ50_RS05975	COG2949	membrane
CEQ50_RS05985	COG0281	malic enzyme
CEQ50_RS05995	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CEQ50_RS06000	COG2985	domain, Protein
CEQ50_RS06000	COG3273	potassium ion transport
CEQ50_RS06005	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEQ50_RS06015	COG1737	Transcriptional regulator
CEQ50_RS06020	COG0076	glutamate decarboxylase activity
CEQ50_RS06030	COG2431	L-lysine efflux transmembrane transporter activity
CEQ50_RS06040	COG3070	regulator of competence-specific genes
CEQ50_RS06055	COG4191	Histidine kinase
CEQ50_RS06055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ50_RS06065	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CEQ50_RS06070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CEQ50_RS06075	COG2915	High frequency lysogenization protein hflD homolog
CEQ50_RS06080	COG0482	sulfurtransferase activity
CEQ50_RS06090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ50_RS06095	COG2916	Histone family protein nucleoid-structuring protein H-NS
CEQ50_RS06100	COG1757	Na H antiporter
CEQ50_RS06105	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CEQ50_RS06110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEQ50_RS06115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEQ50_RS06120	COG0131	Imidazoleglycerol-phosphate dehydratase
CEQ50_RS06120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEQ50_RS06125	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEQ50_RS06130	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CEQ50_RS06135	COG0107	imidazoleglycerol-phosphate synthase activity
CEQ50_RS06140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CEQ50_RS06140	COG0140	phosphoribosyl-ATP diphosphatase activity
CEQ50_RS06145	COG1187	pseudouridine synthase activity
CEQ50_RS06155	COG1278	Cold shock
CEQ50_RS06160	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CEQ50_RS06165	COG0542	response to heat
CEQ50_RS06170	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CEQ50_RS06175	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CEQ50_RS06180	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CEQ50_RS06195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEQ50_RS06200	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEQ50_RS06205	COG0297	glycogen (starch) synthase activity
CEQ50_RS06225	COG3070	regulator of competence-specific genes
CEQ50_RS06230	COG1609	Transcriptional regulator
CEQ50_RS06240	COG0745	RESPONSE REGULATOR receiver
CEQ50_RS06245	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CEQ50_RS06250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEQ50_RS06260	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CEQ50_RS06265	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CEQ50_RS06280	COG0189	ligase activity
CEQ50_RS06280	COG4067	protein conserved in archaea
CEQ50_RS06285	COG0500	methyltransferase
CEQ50_RS06290	COG4106	trans-aconitate 2-methyltransferase activity
CEQ50_RS06295	COG1801	Protein of unknown function DUF72
CEQ50_RS06300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEQ50_RS06305	COG1435	thymidine kinase activity
CEQ50_RS06335	COG2116	formate transmembrane transporter activity
CEQ50_RS06345	COG4459	periplasmic nitrate reductase
CEQ50_RS06350	COG3005	denitrification pathway
CEQ50_RS06355	COG0243	molybdopterin cofactor binding
CEQ50_RS06365	COG1227	inorganic diphosphatase activity
CEQ50_RS06375	COG2814	Major facilitator Superfamily
CEQ50_RS06390	COG4172	Belongs to the ABC transporter superfamily
CEQ50_RS06400	COG4171	peptide transport system, permease
CEQ50_RS06415	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CEQ50_RS06420	COG1842	Phage shock protein A
CEQ50_RS06435	COG0519	Catalyzes the synthesis of GMP from XMP
CEQ50_RS06440	COG0626	cystathionine gamma-synthase activity
CEQ50_RS06450	COG0733	neurotransmitter:sodium symporter activity
CEQ50_RS06455	COG0564	pseudouridine synthase activity
CEQ50_RS06465	COG2200	EAL domain
CEQ50_RS06470	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEQ50_RS06475	COG4136	ATPase activity
CEQ50_RS06480	COG4135	transport system, permease component
CEQ50_RS06485	COG4134	Bacterial extracellular solute-binding protein
CEQ50_RS06495	COG3313	Fe-S protein
CEQ50_RS06505	COG0737	Belongs to the 5'-nucleotidase family
CEQ50_RS06515	COG0513	Belongs to the DEAD box helicase family
CEQ50_RS06530	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CEQ50_RS06535	COG2205	protein histidine kinase activity
CEQ50_RS06550	COG1061	Type III restriction enzyme res subunit
CEQ50_RS06555	COG1187	pseudouridine synthase activity
CEQ50_RS06560	COG2814	Major facilitator Superfamily
CEQ50_RS06570	COG0702	epimerase
CEQ50_RS06575	COG0534	Mate efflux family protein
CEQ50_RS06580	COG4181	ATPase activity
CEQ50_RS06595	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CEQ50_RS06650	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEQ50_RS06655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEQ50_RS06660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEQ50_RS06670	COG0840	transmembrane signaling receptor activity
CEQ50_RS06685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ50_RS06685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_RS06685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ50_RS06690	COG2207	Transcriptional regulator
CEQ50_RS06700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ50_RS06710	COG1342	Belongs to the UPF0251 family
CEQ50_RS06730	COG1129	ABC transporter
CEQ50_RS06740	COG0583	DNA-binding transcription factor activity
CEQ50_RS06745	COG1902	pentaerythritol trinitrate reductase activity
CEQ50_RS06750	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEQ50_RS06755	COG5002	protein histidine kinase activity
CEQ50_RS06760	COG0745	RESPONSE REGULATOR receiver
CEQ50_RS06790	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CEQ50_RS06795	COG0372	Belongs to the citrate synthase family
CEQ50_RS06800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CEQ50_RS06805	COG2828	Protein conserved in bacteria
CEQ50_RS06825	COG0561	phosphatase activity
CEQ50_RS06830	COG0602	queuosine metabolic process
CEQ50_RS06870	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEQ50_RS06875	COG1254	Belongs to the acylphosphatase family
CEQ50_RS06880	COG2920	part of a sulfur-relay system
CEQ50_RS06885	COG0670	Belongs to the BI1 family
CEQ50_RS06890	COG1126	abc transporter atp-binding protein
CEQ50_RS06895	COG0765	amino acid transport
CEQ50_RS06900	COG4597	amino acid ABC transporter
CEQ50_RS06905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ50_RS06910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEQ50_RS06910	COG1648	precorrin-2 dehydrogenase activity
CEQ50_RS06915	COG1666	GTP binding
CEQ50_RS06920	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEQ50_RS06925	COG0574	Belongs to the PEP-utilizing enzyme family
CEQ50_RS06925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEQ50_RS06940	COG2996	Protein conserved in bacteria
CEQ50_RS06950	COG3008	intermembrane lipid transfer
CEQ50_RS06955	COG2995	paraquat-inducible protein a
CEQ50_RS06960	COG1132	(ABC) transporter
CEQ50_RS06965	COG1956	GAF domain-containing protein
CEQ50_RS06970	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CEQ50_RS06985	COG0308	aminopeptidase N
CEQ50_RS06995	COG2902	Dehydrogenase
CEQ50_RS07000	COG0167	dihydroorotate dehydrogenase activity
CEQ50_RS07010	COG0116	Belongs to the methyltransferase superfamily
CEQ50_RS07010	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEQ50_RS07020	COG0488	(ABC) transporter
CEQ50_RS07035	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEQ50_RS07040	COG1067	ATP-dependent peptidase activity
CEQ50_RS07045	COG3120	sequence-specific DNA binding
CEQ50_RS07095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEQ50_RS07125	COG0583	DNA-binding transcription factor activity
CEQ50_RS07130	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CEQ50_RS07140	COG3278	Belongs to the heme-copper respiratory oxidase family
CEQ50_RS07155	COG2010	Cytochrome c
CEQ50_RS07165	COG2217	Heavy metal translocating P-type atpase
CEQ50_RS07180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEQ50_RS07185	COG0589	response to stress
CEQ50_RS07210	COG3842	ATPase activity
CEQ50_RS07215	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEQ50_RS07220	COG1177	transmembrane transport
CEQ50_RS07225	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEQ50_RS07240	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEQ50_RS07245	COG0004	ammonium transporteR
CEQ50_RS07250	COG0488	(ABC) transporter
CEQ50_RS07255	COG2197	response regulator
CEQ50_RS07265	COG2271	Major facilitator Superfamily
CEQ50_RS07270	COG1840	ABC-type Fe3 transport system, periplasmic component
CEQ50_RS07280	COG3842	ATPase activity
CEQ50_RS07285	COG0746	molybdenum cofactor guanylyltransferase activity
CEQ50_RS07290	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEQ50_RS07300	COG1940	carbohydrate kinase activity
CEQ50_RS07305	COG3148	PFAM DTW domain containing protein
CEQ50_RS07315	COG0840	transmembrane signaling receptor activity
CEQ50_RS07320	COG0791	NLP P60 protein
CEQ50_RS07330	COG3001	Fructosamine kinase
CEQ50_RS07345	COG1793	dna ligase
CEQ50_RS07350	COG4667	esterase of the alpha-beta hydrolase superfamily
CEQ50_RS07365	COG0848	biopolymer transport protein
CEQ50_RS07370	COG0811	peptide transport
CEQ50_RS07375	COG0811	peptide transport
CEQ50_RS07405	COG0625	glutathione transferase activity
CEQ50_RS07415	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CEQ50_RS07425	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEQ50_RS07440	COG1115	amino acid carrier protein
CEQ50_RS07445	COG1280	lysine exporter protein (LysE YggA)
CEQ50_RS07450	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CEQ50_RS07455	COG0477	Major facilitator Superfamily
CEQ50_RS07460	COG0583	DNA-binding transcription factor activity
CEQ50_RS07470	COG1643	Atp-dependent helicase
CEQ50_RS07490	COG3706	GGDEF domain
CEQ50_RS07505	COG0443	Heat shock 70 kDa protein
CEQ50_RS07535	COG1609	Transcriptional regulator
CEQ50_RS07540	COG2723	6-phospho-beta-galactosidase activity
CEQ50_RS07545	COG0513	Belongs to the DEAD box helicase family
CEQ50_RS07550	COG0243	molybdopterin cofactor binding
CEQ50_RS07555	COG3005	denitrification pathway
CEQ50_RS07560	COG1278	Cold shock
CEQ50_RS07575	COG4191	Histidine kinase
CEQ50_RS07575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ50_RS07580	COG0471	metal ion transport
CEQ50_RS07590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEQ50_RS07610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ50_RS07620	COG3768	UPF0283 membrane protein
CEQ50_RS07625	COG3106	COG3106 Predicted ATPase
CEQ50_RS07650	COG0814	amino acid
CEQ50_RS07655	COG1760	l-serine dehydratase
CEQ50_RS07665	COG2356	endonuclease I
CEQ50_RS07670	COG0720	synthase
CEQ50_RS07675	COG0840	transmembrane signaling receptor activity
CEQ50_RS07680	COG0017	Asparaginyl-tRNA synthetase
CEQ50_RS07690	COG2201	protein-glutamate methylesterase activity
CEQ50_RS07695	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CEQ50_RS07700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CEQ50_RS07705	COG0835	chemotaxis
CEQ50_RS07715	COG0643	Histidine kinase
CEQ50_RS07715	COG2198	Histidine kinase
CEQ50_RS07725	COG0745	RESPONSE REGULATOR receiver
CEQ50_RS07735	COG3437	response regulator, receiver
CEQ50_RS07735	COG2770	Histidine kinase
CEQ50_RS07740	COG1448	Aminotransferase
CEQ50_RS07745	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CEQ50_RS07755	COG0840	transmembrane signaling receptor activity
CEQ50_RS07760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEQ50_RS07765	COG1846	Transcriptional regulator
CEQ50_RS07780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEQ50_RS07785	COG3108	Peptidase M15
CEQ50_RS07790	COG2989	Protein conserved in bacteria
CEQ50_RS07820	COG1940	carbohydrate kinase activity
CEQ50_RS07825	COG4771	TonB-dependent receptor
CEQ50_RS07830	COG0748	coenzyme F420 binding
CEQ50_RS07835	COG3721	Heme iron utilization protein
CEQ50_RS07845	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CEQ50_RS07850	COG0811	peptide transport
CEQ50_RS07855	COG0848	biopolymer transport protein
CEQ50_RS07865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ50_RS07870	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CEQ50_RS07875	COG1054	Belongs to the UPF0176 family
CEQ50_RS07890	COG1621	beta-fructofuranosidase activity
CEQ50_RS07900	COG1263	PTS System
CEQ50_RS07900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ50_RS07905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ50_RS07910	COG2200	EAL domain
CEQ50_RS07915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEQ50_RS07920	COG0840	transmembrane signaling receptor activity
CEQ50_RS07925	COG1294	oxidase, subunit
CEQ50_RS07930	COG1271	oxidase subunit
CEQ50_RS07955	COG3220	belongs to the UPF0276 family
CEQ50_RS07975	COG1294	oxidase, subunit
CEQ50_RS07985	COG0251	oxidation-reduction process
CEQ50_RS08070	COG3064	Membrane
CEQ50_RS08070	COG4991	sh3 domain protein
CEQ50_RS08070	COG0515	serine threonine protein kinase
CEQ50_RS08095	COG1716	ATPase activity
CEQ50_RS08115	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEQ50_RS08190	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CEQ50_RS08230	COG0835	chemotaxis
CEQ50_RS08230	COG0784	Response regulator, receiver
CEQ50_RS08240	COG4565	transcriptional regulatory protein
CEQ50_RS08245	COG3290	protein histidine kinase activity
CEQ50_RS08260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ50_RS08285	COG3063	Type IV pilus biogenesis stability protein PilW
CEQ50_RS08300	COG1451	nucleotide metabolic process
CEQ50_RS08310	COG0583	DNA-binding transcription factor activity
CEQ50_RS08335	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CEQ50_RS08340	COG4139	cobalamin transport
CEQ50_RS08345	COG2988	succinylglutamate desuccinylase activity
CEQ50_RS08360	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CEQ50_RS08365	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CEQ50_RS08370	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CEQ50_RS08370	COG1073	alpha beta
CEQ50_RS08370	COG3064	Membrane
CEQ50_RS08375	COG3064	Membrane
CEQ50_RS08375	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CEQ50_RS08375	COG1073	alpha beta
CEQ50_RS08380	COG2994	toxin metabolic process
CEQ50_RS08410	COG0702	epimerase
CEQ50_RS08415	COG1823	symporter activity
CEQ50_RS08420	COG2925	Exonuclease
CEQ50_RS08425	COG1380	Effector of murein hydrolase LrgA
CEQ50_RS08430	COG1346	cytolysis
CEQ50_RS08440	COG5001	Diguanylate cyclase
CEQ50_RS08455	COG0500	methyltransferase
CEQ50_RS08465	COG0776	regulation of translation
CEQ50_RS08470	COG0072	phenylalanine-tRNA ligase activity
CEQ50_RS08470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEQ50_RS08475	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CEQ50_RS08515	COG0322	excinuclease ABC activity
CEQ50_RS08520	COG2197	response regulator
CEQ50_RS08550	COG2433	Pfam Transposase IS66
CEQ50_RS08575	COG0417	DNA replication proofreading
CEQ50_RS08630	COG0417	DNA replication proofreading
CEQ50_RS08640	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEQ50_RS08645	COG3099	Belongs to the UPF0263 family
CEQ50_RS08650	COG3097	Belongs to the UPF0267 family
CEQ50_RS08660	COG1228	amidohydrolase
CEQ50_RS08665	COG0010	Belongs to the arginase family
CEQ50_RS08675	COG2986	histidine ammonia-lyase
CEQ50_RS08690	COG0277	FAD linked oxidase domain protein
CEQ50_RS08690	COG0247	lactate metabolic process
CEQ50_RS08720	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEQ50_RS08725	COG1960	acyl-CoA dehydrogenase activity
CEQ50_RS08755	COG5001	Diguanylate cyclase
CEQ50_RS08755	COG3300	MHYT domain
CEQ50_RS08775	COG2433	Pfam Transposase IS66
CEQ50_RS08795	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CEQ50_RS08815	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CEQ50_RS08835	COG0494	nUDIX hydrolase
CEQ50_RS08905	COG2003	Belongs to the UPF0758 family
CEQ50_RS08920	COG0328	RNA-DNA hybrid ribonuclease activity
CEQ50_RS08960	COG0582	viral genome integration into host DNA
CEQ50_RS08975	COG5002	protein histidine kinase activity
CEQ50_RS08975	COG0784	Response regulator, receiver
CEQ50_RS08985	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CEQ50_RS08990	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CEQ50_RS08995	COG2885	chlorophyll binding
CEQ50_RS09000	COG0823	Involved in the tonB-independent uptake of proteins
CEQ50_RS09015	COG0811	peptide transport
CEQ50_RS09020	COG0824	Thioesterase
CEQ50_RS09025	COG3790	cyd operon protein YbgE
CEQ50_RS09030	COG4890	Cyd operon protein YbgT
CEQ50_RS09035	COG1294	oxidase, subunit
CEQ50_RS09040	COG1271	oxidase subunit
CEQ50_RS09045	COG2255	four-way junction helicase activity
CEQ50_RS09050	COG0632	four-way junction helicase activity
CEQ50_RS09055	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CEQ50_RS09060	COG0215	cysteine-tRNA ligase activity
CEQ50_RS09065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEQ50_RS09070	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEQ50_RS09075	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CEQ50_RS09080	COG3012	SEC-C Motif Domain Protein
CEQ50_RS09090	COG1199	ATP-dependent helicase activity
CEQ50_RS09100	COG3923	Primosomal replication protein n
CEQ50_RS09110	COG0840	transmembrane signaling receptor activity
CEQ50_RS09115	COG0708	Exodeoxyribonuclease III
CEQ50_RS09120	COG4160	amino acid transport
CEQ50_RS09150	COG1882	Formate acetyltransferase
CEQ50_RS09165	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEQ50_RS09175	COG3013	Belongs to the UPF0304 family
CEQ50_RS09180	COG2766	serine protein kinase
CEQ50_RS09185	COG2718	Belongs to the UPF0229 family
CEQ50_RS09190	COG2719	SpoVR family
CEQ50_RS09195	COG3038	cytochrome b561
CEQ50_RS09200	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CEQ50_RS09215	COG1132	(ABC) transporter
CEQ50_RS09220	COG0658	competence protein
CEQ50_RS09220	COG2333	competence protein COMEC
CEQ50_RS09230	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEQ50_RS09235	COG1136	(ABC) transporter
CEQ50_RS09240	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEQ50_RS09250	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEQ50_RS09265	COG1252	NADH dehydrogenase
CEQ50_RS09270	COG3150	esterase
CEQ50_RS09295	COG0537	adenosine 5'-monophosphoramidase activity
CEQ50_RS09310	COG2186	Transcriptional regulator
CEQ50_RS09315	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CEQ50_RS09325	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CEQ50_RS09330	COG2226	methyltransferase
CEQ50_RS09335	COG0156	8-amino-7-oxononanoate synthase activity
CEQ50_RS09340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEQ50_RS09345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CEQ50_RS09355	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEQ50_RS09360	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CEQ50_RS09365	COG0653	protein targeting
CEQ50_RS09370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEQ50_RS09380	COG4120	Belongs to the binding-protein-dependent transport system permease family
CEQ50_RS09390	COG3092	negative regulation of chromosome organization
CEQ50_RS09395	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEQ50_RS09400	COG0857	belongs to the CobB CobQ family
CEQ50_RS09400	COG0280	phosphate acetyltransferase
CEQ50_RS09405	COG0435	Glutathione S-transferase
CEQ50_RS09415	COG0444	Belongs to the ABC transporter superfamily
CEQ50_RS09420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEQ50_RS09425	COG0601	transmembrane transport
CEQ50_RS09440	COG0784	Response regulator, receiver
CEQ50_RS09440	COG5002	protein histidine kinase activity
CEQ50_RS09465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEQ50_RS09470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEQ50_RS09490	COG1215	transferase activity, transferring glycosyl groups
CEQ50_RS09520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEQ50_RS09525	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEQ50_RS09530	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ50_RS09545	COG1335	isochorismatase
CEQ50_RS09560	COG1538	Outer membrane efflux protein
CEQ50_RS09565	COG1566	PFAM secretion protein HlyD family protein
CEQ50_RS09580	COG0800	Aldolase
CEQ50_RS09585	COG2610	gluconate transmembrane transporter activity
CEQ50_RS09590	COG3265	gluconokinase activity
CEQ50_RS09595	COG0129	dihydroxy-acid dehydratase activity
CEQ50_RS09600	COG1609	Transcriptional regulator
CEQ50_RS09615	COG5002	protein histidine kinase activity
CEQ50_RS09615	COG3850	Histidine kinase
CEQ50_RS09625	COG2985	domain, Protein
CEQ50_RS09640	COG2194	sulfuric ester hydrolase activity
CEQ50_RS09645	COG0642	Histidine kinase
CEQ50_RS09650	COG0745	RESPONSE REGULATOR receiver
CEQ50_RS09670	COG1022	Amp-dependent synthetase and ligase
CEQ50_RS09695	COG3706	GGDEF domain
CEQ50_RS09710	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CEQ50_RS09715	COG1946	Acyl-CoA thioesterase
CEQ50_RS09720	COG1522	sequence-specific DNA binding
CEQ50_RS09755	COG0318	PFAM AMP-dependent synthetase and ligase
CEQ50_RS09765	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CEQ50_RS09775	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CEQ50_RS09790	COG0436	Aminotransferase
CEQ50_RS09795	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CEQ50_RS09800	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CEQ50_RS09815	COG0616	signal peptide processing
CEQ50_RS09820	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ50_RS09825	COG0835	chemotaxis
CEQ50_RS09825	COG0784	Response regulator, receiver
CEQ50_RS09830	COG1940	carbohydrate kinase activity
CEQ50_RS09840	COG4667	esterase of the alpha-beta hydrolase superfamily
CEQ50_RS09850	COG0733	neurotransmitter:sodium symporter activity
CEQ50_RS09860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ50_RS09860	COG1263	PTS System
CEQ50_RS09865	COG0084	hydrolase, TatD family'
CEQ50_RS09870	COG0470	DNA polymerase III
CEQ50_RS09875	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CEQ50_RS09880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEQ50_RS09885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEQ50_RS09910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEQ50_RS09925	COG1399	metal-binding, possibly nucleic acid-binding protein
CEQ50_RS09930	COG0424	maF-like protein
CEQ50_RS09935	COG0564	pseudouridine synthase activity
CEQ50_RS09940	COG1530	ribonuclease E activity
CEQ50_RS09950	COG1454	alcohol dehydrogenase
CEQ50_RS09950	COG1012	belongs to the aldehyde dehydrogenase family
CEQ50_RS09955	COG2095	MarC family integral membrane protein
CEQ50_RS09960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEQ50_RS09980	COG3082	Protein of unknown function (DUF1414)
CEQ50_RS09995	COG0243	molybdopterin cofactor binding
CEQ50_RS10000	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CEQ50_RS10020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEQ50_RS10025	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CEQ50_RS10045	COG2853	Lipoprotein
CEQ50_RS10060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEQ50_RS10065	COG1138	Cytochrome C-type biogenesis protein
CEQ50_RS10070	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CEQ50_RS10080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEQ50_RS10085	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEQ50_RS10090	COG4133	protoheme IX ABC transporter activity
CEQ50_RS10100	COG0835	chemotaxis
CEQ50_RS10110	COG1192	Involved in chromosome partitioning
CEQ50_RS10115	COG2201	protein-glutamate methylesterase activity
CEQ50_RS10120	COG2198	Histidine kinase
CEQ50_RS10120	COG0784	Response regulator, receiver
CEQ50_RS10120	COG0643	Histidine kinase
CEQ50_RS10125	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CEQ50_RS10150	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CEQ50_RS10155	COG2062	phosphohistidine phosphatase, SixA
CEQ50_RS10160	COG1025	Belongs to the peptidase M16 family
CEQ50_RS10165	COG3102	Protein conserved in bacteria
CEQ50_RS10190	COG1918	ferrous iron import across plasma membrane
CEQ50_RS10195	COG4977	sequence-specific DNA binding
CEQ50_RS10200	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CEQ50_RS10205	COG1121	(ABC) transporter
CEQ50_RS10210	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEQ50_RS10225	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEQ50_RS10230	COG0567	Dehydrogenase, E1 component
CEQ50_RS10245	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CEQ50_RS10260	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEQ50_RS10270	COG0033	Phosphoglucomutase
CEQ50_RS10275	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CEQ50_RS10280	COG0596	Alpha beta hydrolase
CEQ50_RS10295	COG1346	cytolysis
CEQ50_RS10305	COG0583	DNA-binding transcription factor activity
CEQ50_RS10315	COG0735	belongs to the Fur family
CEQ50_RS10320	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEQ50_RS10325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEQ50_RS10330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEQ50_RS10335	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CEQ50_RS10335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEQ50_RS10340	COG0431	NADPH-dependent FMN reductase
CEQ50_RS10350	COG3101	peptidyl-lysine hydroxylation
CEQ50_RS10355	COG2860	membrane
CEQ50_RS10360	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEQ50_RS10365	COG2890	protein-(glutamine-N5) methyltransferase activity
CEQ50_RS10370	COG2840	Smr protein MutS2
CEQ50_RS10380	COG1684	flagellar biosynthetic protein fliR
CEQ50_RS10385	COG1987	bacterial-type flagellum assembly
CEQ50_RS10435	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CEQ50_RS10445	COG1677	Flagellar hook-basal body complex protein FliE
CEQ50_RS10465	COG1516	flagellar protein fliS
CEQ50_RS10475	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CEQ50_RS10500	COG2837	iron assimilation
CEQ50_RS10525	COG1393	Belongs to the ArsC family
CEQ50_RS10545	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CEQ50_RS10560	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEQ50_RS10580	COG4783	chaperone-mediated protein folding
CEQ50_RS10585	COG1393	Belongs to the ArsC family
CEQ50_RS10605	COG2233	PERMEase
CEQ50_RS10610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEQ50_RS10620	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CEQ50_RS10625	COG2912	Transglutaminase-like superfamily
CEQ50_RS10630	COG3094	Invasion gene expression up-regulator, SirB
CEQ50_RS10635	COG2890	protein-(glutamine-N5) methyltransferase activity
CEQ50_RS10640	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CEQ50_RS10645	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CEQ50_RS10650	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CEQ50_RS10660	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEQ50_RS10665	COG0193	aminoacyl-tRNA hydrolase activity
CEQ50_RS10770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CEQ50_RS10780	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEQ50_RS10780	COG3951	Flagellar rod assembly protein muramidase FlgJ
CEQ50_RS10785	COG1706	bacterial-type flagellum-dependent cell motility
CEQ50_RS10790	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CEQ50_RS10800	COG4787	bacterial-type flagellum-dependent cell motility
CEQ50_RS10805	COG1749	Flagellar hook protein flgE
CEQ50_RS10820	COG1815	bacterial-type flagellum-dependent cell motility
CEQ50_RS10830	COG0835	chemotaxis
CEQ50_RS10830	COG0784	Response regulator, receiver
CEQ50_RS10840	COG2747	anti-sigma28 factor FlgM
CEQ50_RS10885	COG2217	Heavy metal translocating P-type atpase
CEQ50_RS10885	COG2608	mercury ion transmembrane transporter activity
CEQ50_RS10910	COG1187	pseudouridine synthase activity
CEQ50_RS10915	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEQ50_RS10920	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEQ50_RS10925	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CEQ50_RS10930	COG0121	glutamine amidotransferase
CEQ50_RS10935	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEQ50_RS10955	COG0328	RNA-DNA hybrid ribonuclease activity
CEQ50_RS10960	COG2226	methyltransferase
CEQ50_RS10965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEQ50_RS10970	COG0741	lytic transglycosylase activity
CEQ50_RS10970	COG1388	LysM domain
CEQ50_RS10980	COG3021	interspecies interaction between organisms
CEQ50_RS10985	COG0347	Belongs to the P(II) protein family
CEQ50_RS10995	COG0037	tRNA processing
CEQ50_RS11000	COG0825	malonyl-CoA metabolic process
CEQ50_RS11005	COG0587	DNA-directed DNA polymerase activity
CEQ50_RS11015	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEQ50_RS11025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEQ50_RS11030	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEQ50_RS11035	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CEQ50_RS11045	COG0750	zinc metalloprotease
CEQ50_RS11050	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CEQ50_RS11055	COG0575	Belongs to the CDS family
CEQ50_RS11060	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CEQ50_RS11065	COG0233	cytoplasmic translational termination
CEQ50_RS11075	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEQ50_RS11080	COG0052	Belongs to the universal ribosomal protein uS2 family
CEQ50_RS11085	COG0024	Methionine aminopeptidase
CEQ50_RS11090	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CEQ50_RS11100	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CEQ50_RS11105	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CEQ50_RS11110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEQ50_RS11130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEQ50_RS11130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEQ50_RS11135	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CEQ50_RS11140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CEQ50_RS11145	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CEQ50_RS11155	COG1073	alpha beta
CEQ50_RS11160	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CEQ50_RS11165	COG2252	PERMEase
CEQ50_RS11170	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEQ50_RS11175	COG0189	ligase activity
CEQ50_RS11175	COG4067	protein conserved in archaea
CEQ50_RS11180	COG0189	ligase activity
CEQ50_RS11190	COG0733	neurotransmitter:sodium symporter activity
CEQ50_RS11195	COG2203	Gaf domain
CEQ50_RS11195	COG3706	GGDEF domain
CEQ50_RS11195	COG5001	Diguanylate cyclase
CEQ50_RS11195	COG4251	negative regulation of phosphorylation
CEQ50_RS11220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEQ50_RS11230	COG1477	protein flavinylation
CEQ50_RS11265	COG0271	Belongs to the BolA IbaG family
CEQ50_RS11285	COG2211	Major facilitator Superfamily
CEQ50_RS11295	COG1595	DNA-templated transcription, initiation
CEQ50_RS11310	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEQ50_RS11320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEQ50_RS11325	COG2166	iron-sulfur cluster assembly
CEQ50_RS11330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CEQ50_RS11335	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CEQ50_RS11345	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CEQ50_RS11345	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEQ50_RS11355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEQ50_RS11360	COG1074	ATP-dependent DNA helicase activity
CEQ50_RS11365	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CEQ50_RS11380	COG3141	response to X-ray
CEQ50_RS11385	COG2171	N-acyltransferase activity
CEQ50_RS11415	COG1609	Transcriptional regulator
CEQ50_RS11425	COG1085	galactose-1-phosphate uridylyltransferase
CEQ50_RS11430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEQ50_RS11435	COG0534	Mate efflux family protein
CEQ50_RS11445	COG0784	Response regulator, receiver
CEQ50_RS11445	COG3437	response regulator, receiver
CEQ50_RS11450	COG1022	Amp-dependent synthetase and ligase
CEQ50_RS11455	COG4628	conserved protein (DUF2132)
CEQ50_RS11460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEQ50_RS11465	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CEQ50_RS11475	COG0560	Phosphoserine phosphatase
CEQ50_RS11485	COG0813	purine-nucleoside phosphorylase activity
CEQ50_RS11490	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CEQ50_RS11495	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CEQ50_RS11500	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CEQ50_RS11505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEQ50_RS11510	COG0084	hydrolase, TatD family'
CEQ50_RS11515	COG3022	response to hydroperoxide
CEQ50_RS11520	COG1115	amino acid carrier protein
CEQ50_RS11535	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CEQ50_RS11540	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CEQ50_RS11545	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CEQ50_RS11550	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CEQ50_RS11555	COG0083	homoserine kinase activity
CEQ50_RS11570	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CEQ50_RS11575	COG0745	RESPONSE REGULATOR receiver
CEQ50_RS11585	COG0784	Response regulator, receiver
CEQ50_RS11585	COG2198	Histidine kinase
CEQ50_RS11585	COG5002	protein histidine kinase activity
CEQ50_RS11590	COG1242	4 iron, 4 sulfur cluster binding
CEQ50_RS11600	COG0069	glutamate synthase activity
CEQ50_RS11600	COG0067	glutamate synthase
CEQ50_RS11600	COG0070	glutamate synthase
CEQ50_RS11610	COG0067	glutamate synthase
CEQ50_RS11610	COG0069	glutamate synthase activity
CEQ50_RS11610	COG0070	glutamate synthase
CEQ50_RS11615	COG0493	'glutamate synthase
CEQ50_RS11630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CEQ50_RS11640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEQ50_RS11645	COG2860	membrane
CEQ50_RS11650	COG0583	DNA-binding transcription factor activity
CEQ50_RS11655	COG0730	response to heat
CEQ50_RS11660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEQ50_RS11665	COG0505	Belongs to the CarA family
CEQ50_RS11670	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CEQ50_RS11675	COG0494	nUDIX hydrolase
CEQ50_RS11685	COG0653	protein targeting
CEQ50_RS11695	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CEQ50_RS11700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CEQ50_RS11705	COG0849	cell division
CEQ50_RS11710	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CEQ50_RS11715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEQ50_RS11720	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CEQ50_RS11725	COG0772	Belongs to the SEDS family
CEQ50_RS11730	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEQ50_RS11740	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEQ50_RS11745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEQ50_RS11750	COG0768	penicillin binding
CEQ50_RS11755	COG3116	cell division
CEQ50_RS11760	COG0275	rRNA processing
CEQ50_RS11770	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CEQ50_RS11775	COG3107	peptidoglycan biosynthetic process
CEQ50_RS11780	COG0792	nuclease activity
CEQ50_RS11785	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEQ50_RS11795	COG2969	positive regulation of protein catabolic process
CEQ50_RS11800	COG0625	glutathione transferase activity
CEQ50_RS11805	COG2857	Cytochrome c1
CEQ50_RS11810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CEQ50_RS11815	COG0723	plastoquinol--plastocyanin reductase activity
CEQ50_RS11825	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CEQ50_RS11835	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CEQ50_RS11840	COG3105	Protein conserved in bacteria
CEQ50_RS11845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEQ50_RS11850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEQ50_RS11855	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CEQ50_RS11860	COG0187	DNA topoisomerase II activity
CEQ50_RS11865	COG3150	esterase
CEQ50_RS11875	COG3151	Protein conserved in bacteria
CEQ50_RS11880	COG0494	nUDIX hydrolase
CEQ50_RS11885	COG1538	Outer membrane efflux protein
CEQ50_RS11895	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CEQ50_RS11910	COG3025	triphosphatase activity
CEQ50_RS11915	COG1392	Phosphate transport regulator
CEQ50_RS11920	COG0306	phosphate transporter
CEQ50_RS11925	COG4991	sh3 domain protein
CEQ50_RS11935	COG3267	Type II secretory pathway component ExeA
CEQ50_RS11935	COG3409	Peptidoglycan-binding domain 1 protein
CEQ50_RS11940	COG0617	tRNA 3'-terminal CCA addition
CEQ50_RS11950	COG0504	CTP synthase activity
CEQ50_RS11955	COG3956	TIGRFAM MazG family protein
CEQ50_RS11960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEQ50_RS11965	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEQ50_RS11970	COG2205	protein histidine kinase activity
CEQ50_RS11970	COG4999	Histidine kinase
CEQ50_RS11970	COG3437	response regulator, receiver
CEQ50_RS11970	COG3850	Histidine kinase
CEQ50_RS11975	COG0736	holo-[acyl-carrier-protein] synthase activity
CEQ50_RS11980	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CEQ50_RS11985	COG1381	Involved in DNA repair and RecF pathway recombination
CEQ50_RS11990	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CEQ50_RS11995	COG0571	ribonuclease III activity
CEQ50_RS12005	COG0481	GTPase activity
CEQ50_RS12010	COG3086	response to oxidative stress
CEQ50_RS12025	COG1595	DNA-templated transcription, initiation
CEQ50_RS12030	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CEQ50_RS12040	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CEQ50_RS12060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEQ50_RS12065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEQ50_RS12070	COG3079	Belongs to the UPF0149 family
CEQ50_RS12075	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CEQ50_RS12085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEQ50_RS12095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEQ50_RS12115	COG0028	Belongs to the TPP enzyme family
CEQ50_RS12120	COG1022	Amp-dependent synthetase and ligase
CEQ50_RS12125	COG0583	DNA-binding transcription factor activity
CEQ50_RS12145	COG0473	3-isopropylmalate dehydrogenase activity
CEQ50_RS12155	COG0066	3-isopropylmalate dehydratase activity
CEQ50_RS12215	COG0795	lipopolysaccharide-transporting ATPase activity
CEQ50_RS12220	COG0795	lipopolysaccharide-transporting ATPase activity
CEQ50_RS12225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEQ50_RS12230	COG2927	DNA polymerase III (CHI subunit)
CEQ50_RS12235	COG0525	valine-tRNA ligase activity
CEQ50_RS12240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEQ50_RS12245	COG0564	pseudouridine synthase activity
CEQ50_RS12255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEQ50_RS12265	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CEQ50_RS12280	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CEQ50_RS12285	COG0251	oxidation-reduction process
CEQ50_RS12300	COG0204	Acyl-transferase
CEQ50_RS12305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEQ50_RS12310	COG5007	Belongs to the BolA IbaG family
CEQ50_RS12320	COG2854	intermembrane phospholipid transfer
CEQ50_RS12325	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CEQ50_RS12330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEQ50_RS12335	COG1127	ABC transporter
CEQ50_RS12345	COG0517	IMP dehydrogenase activity
CEQ50_RS12345	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CEQ50_RS12350	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CEQ50_RS12360	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CEQ50_RS12365	COG1137	ATPase activity
CEQ50_RS12375	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEQ50_RS12380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_RS12385	COG1660	Displays ATPase and GTPase activities
CEQ50_RS12390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_RS12395	COG2239	Acts as a magnesium transporter
CEQ50_RS12400	COG0312	modulator of DNA gyrase
CEQ50_RS12405	COG3028	Belongs to the UPF0307 family
CEQ50_RS12410	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CEQ50_RS12415	COG1178	ABC-type Fe3 transport system permease component
CEQ50_RS12425	COG0163	prenyltransferase activity
CEQ50_RS12430	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEQ50_RS12435	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CEQ50_RS12440	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CEQ50_RS12450	COG2105	PFAM AIG2 family protein
CEQ50_RS12455	COG2911	Protein conserved in bacteria
CEQ50_RS12460	COG0729	surface antigen
CEQ50_RS12465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ50_RS12470	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CEQ50_RS12505	COG0529	Catalyzes the synthesis of activated sulfate
CEQ50_RS12510	COG2895	sulfate adenylyltransferase (ATP) activity
CEQ50_RS12515	COG0175	sulfate reduction
CEQ50_RS12520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEQ50_RS12520	COG1648	precorrin-2 dehydrogenase activity
CEQ50_RS12525	COG0737	Belongs to the 5'-nucleotidase family
CEQ50_RS12565	COG0513	Belongs to the DEAD box helicase family
CEQ50_RS12570	COG2153	protein acetylation
CEQ50_RS12575	COG3266	domain, Protein
CEQ50_RS12575	COG3061	Opacity-associated protein A
CEQ50_RS12580	COG0545	Peptidyl-prolyl cis-trans isomerase
CEQ50_RS12585	COG0203	ribosomal protein L17
CEQ50_RS12590	COG0202	RNA polymerase activity
CEQ50_RS12595	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEQ50_RS12600	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CEQ50_RS12605	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEQ50_RS12610	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEQ50_RS12615	COG0201	protein transport
CEQ50_RS12620	COG0200	Binds to the 23S rRNA
CEQ50_RS12625	COG1841	ribosomal large subunit assembly
CEQ50_RS12630	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CEQ50_RS12640	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEQ50_RS12645	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEQ50_RS12650	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEQ50_RS12655	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CEQ50_RS12660	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CEQ50_RS12670	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CEQ50_RS12680	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CEQ50_RS12695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEQ50_RS12700	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEQ50_RS12710	COG0088	Forms part of the polypeptide exit tunnel
CEQ50_RS12715	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CEQ50_RS12720	COG0051	transcription antitermination factor activity, RNA binding
CEQ50_RS12725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEQ50_RS12730	COG0557	exoribonuclease II activity
CEQ50_RS12735	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CEQ50_RS12745	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEQ50_RS12755	COG1047	Peptidyl-prolyl cis-trans
CEQ50_RS12760	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CEQ50_RS12770	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEQ50_RS12775	COG0488	(ABC) transporter
CEQ50_RS12785	COG0429	hydrolase of the alpha beta-hydrolase fold
CEQ50_RS12795	COG3954	Phosphoribulokinase
CEQ50_RS12800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEQ50_RS12810	COG1012	belongs to the aldehyde dehydrogenase family
CEQ50_RS12820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEQ50_RS12835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEQ50_RS12845	COG0583	DNA-binding transcription factor activity
CEQ50_RS12860	COG0180	Tryptophanyl-tRNA synthetase
CEQ50_RS12865	COG0546	phosphoglycolate phosphatase activity
CEQ50_RS12870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEQ50_RS12875	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CEQ50_RS12885	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CEQ50_RS12890	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CEQ50_RS12920	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CEQ50_RS12930	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEQ50_RS12930	COG0678	peroxiredoxin activity
CEQ50_RS12935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ50_RS12945	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CEQ50_RS12945	COG0165	Argininosuccinate lyase
CEQ50_RS12950	COG0137	argininosuccinate synthase activity
CEQ50_RS12955	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEQ50_RS12960	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEQ50_RS12965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEQ50_RS12970	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CEQ50_RS12980	COG1045	serine acetyltransferase
CEQ50_RS12985	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEQ50_RS12995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEQ50_RS13000	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CEQ50_RS13005	COG1053	succinate dehydrogenase
CEQ50_RS13010	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEQ50_RS13015	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CEQ50_RS13025	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEQ50_RS13030	COG1509	lysine 2,3-aminomutase activity
CEQ50_RS13045	COG0459	protein refolding
CEQ50_RS13050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CEQ50_RS13080	COG0534	Mate efflux family protein
CEQ50_RS13085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CEQ50_RS13090	COG1575	Belongs to the MenA family. Type 1 subfamily
CEQ50_RS13095	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CEQ50_RS13100	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CEQ50_RS13110	COG1609	Transcriptional regulator
CEQ50_RS13115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEQ50_RS13125	COG0281	malic enzyme
CEQ50_RS13135	COG0626	cystathionine gamma-synthase activity
CEQ50_RS13140	COG0527	aspartate kinase activity
CEQ50_RS13140	COG0460	homoserine dehydrogenase
CEQ50_RS13145	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEQ50_RS13150	COG3074	FtsZ-dependent cytokinesis
CEQ50_RS13155	COG1494	fructose-1,6-bisphosphatase
CEQ50_RS13160	COG0205	6-phosphofructokinase activity
CEQ50_RS13165	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CEQ50_RS13175	COG0745	RESPONSE REGULATOR receiver
CEQ50_RS13180	COG2205	protein histidine kinase activity
CEQ50_RS13185	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEQ50_RS13190	COG1278	Cold shock
CEQ50_RS13195	COG3030	protein affecting phage T7 exclusion by the F plasmid
CEQ50_RS13200	COG1027	Aspartate ammonia-lyase
CEQ50_RS13205	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CEQ50_RS13210	COG1288	antiporter activity
CEQ50_RS13220	COG0549	Belongs to the carbamate kinase family
CEQ50_RS13225	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CEQ50_RS13235	COG0540	Belongs to the ATCase OTCase family
CEQ50_RS13240	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CEQ50_RS13245	COG1438	arginine binding
CEQ50_RS13250	COG4232	protein-disulfide reductase activity
CEQ50_RS13270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEQ50_RS13275	COG2198	Histidine kinase
CEQ50_RS13275	COG0784	Response regulator, receiver
CEQ50_RS13275	COG2205	protein histidine kinase activity
CEQ50_RS13280	COG2814	Major facilitator Superfamily
CEQ50_RS13295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEQ50_RS13300	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CEQ50_RS13305	COG0511	ligase activity, forming carbon-carbon bonds
CEQ50_RS13310	COG0439	Biotin carboxylase
CEQ50_RS13315	COG2264	protein methyltransferase activity
CEQ50_RS13320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEQ50_RS13325	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CEQ50_RS13330	COG0840	transmembrane signaling receptor activity
CEQ50_RS13335	COG0789	Transcriptional regulator
CEQ50_RS13340	COG0138	bifunctional purine biosynthesis protein purh
CEQ50_RS13345	COG0151	Belongs to the GarS family
CEQ50_RS13355	COG0776	regulation of translation
CEQ50_RS13360	COG1253	flavin adenine dinucleotide binding
CEQ50_RS13395	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEQ50_RS13405	COG3068	Protein conserved in bacteria
CEQ50_RS13410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEQ50_RS13415	COG0668	transmembrane transport
CEQ50_RS13420	COG0840	transmembrane signaling receptor activity
CEQ50_RS13435	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CEQ50_RS13445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEQ50_RS13455	COG0438	transferase activity, transferring glycosyl groups
CEQ50_RS13460	COG0367	asparagine synthase
CEQ50_RS13470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEQ50_RS13495	COG1215	transferase activity, transferring glycosyl groups
CEQ50_RS13510	COG1621	beta-fructofuranosidase activity
CEQ50_RS13525	COG0022	dehydrogenase e1 component
CEQ50_RS13530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CEQ50_RS13545	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CEQ50_RS13550	COG1088	dTDP-glucose 4,6-dehydratase activity
CEQ50_RS13560	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CEQ50_RS13565	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CEQ50_RS13585	COG3307	-O-antigen
CEQ50_RS13595	COG0859	PFAM glycosyl transferase family 9
CEQ50_RS13610	COG1519	Transferase
CEQ50_RS13640	COG3642	lipopolysaccharide core region biosynthetic process
CEQ50_RS13645	COG0859	PFAM glycosyl transferase family 9
CEQ50_RS13650	COG0463	Glycosyl transferase, family 2
CEQ50_RS13655	COG0859	PFAM glycosyl transferase family 9
CEQ50_RS13660	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEQ50_RS13675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEQ50_RS13680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CEQ50_RS13685	COG2003	Belongs to the UPF0758 family
CEQ50_RS13690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEQ50_RS13695	COG1309	transcriptional regulator
CEQ50_RS13700	COG1560	Kdo2-lipid A biosynthetic process
CEQ50_RS13705	COG1560	Kdo2-lipid A biosynthetic process
CEQ50_RS13710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CEQ50_RS13715	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CEQ50_RS13720	COG1561	YicC-like family, N-terminal region
CEQ50_RS13735	COG3051	citrate lyase alpha subunit
CEQ50_RS13740	COG2301	Belongs to the HpcH HpaI aldolase family
CEQ50_RS13745	COG3052	prosthetic group binding
CEQ50_RS13750	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CEQ50_RS13765	COG0511	ligase activity, forming carbon-carbon bonds
CEQ50_RS13765	COG5016	pyruvate
CEQ50_RS13770	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CEQ50_RS13780	COG4565	transcriptional regulatory protein
CEQ50_RS13795	COG0612	Peptidase, M16
CEQ50_RS13800	COG2862	Uncharacterized protein family, UPF0114
CEQ50_RS13815	COG1120	ATPase activity
CEQ50_RS13820	COG4774	siderophore transport
CEQ50_RS13825	COG1132	(ABC) transporter
CEQ50_RS13830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEQ50_RS13830	COG1263	PTS System
CEQ50_RS13835	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEQ50_RS13855	COG0514	ATP-dependent DNA helicase (RecQ)
CEQ50_RS13860	COG2962	Rard protein
CEQ50_RS13870	COG1280	lysine exporter protein (LysE YggA)
CEQ50_RS13880	COG0210	DNA helicase
CEQ50_RS13885	COG0339	signal peptide processing
CEQ50_RS13890	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CEQ50_RS13895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEQ50_RS13940	COG3501	Rhs element vgr protein
CEQ50_RS13950	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEQ50_RS13975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEQ50_RS13980	COG0601	transmembrane transport
CEQ50_RS14030	COG1309	transcriptional regulator
CEQ50_RS14035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEQ50_RS14040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ50_RS14045	COG2960	long-chain fatty acid transporting porin activity
CEQ50_RS14050	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CEQ50_RS14070	COG3078	GTPase activator activity
CEQ50_RS14090	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ50_RS14090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEQ50_RS14100	COG0084	hydrolase, TatD family'
CEQ50_RS14105	COG0805	protein transport
CEQ50_RS14110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEQ50_RS14115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEQ50_RS14120	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CEQ50_RS14130	COG2226	methyltransferase
CEQ50_RS14135	COG1322	Protein conserved in bacteria
CEQ50_RS14155	COG2160	L-arabinose isomerase activity
CEQ50_RS14165	COG1069	ribulokinase activity
CEQ50_RS14175	COG1879	ABC-type sugar transport system periplasmic component
CEQ50_RS14180	COG1129	ABC transporter
CEQ50_RS14185	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEQ50_RS14195	COG2081	HI0933 family
CEQ50_RS14210	COG1528	Iron-storage protein
CEQ50_RS14215	COG0589	response to stress
CEQ50_RS14230	COG0742	ribosomal rna small subunit methyltransferase
CEQ50_RS14235	COG1522	sequence-specific DNA binding
CEQ50_RS14255	COG0006	proline dipeptidase activity
CEQ50_RS14255	COG0006	proline dipeptidase activity
CEQ50_RS14260	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEQ50_RS14265	COG2022	thiamine diphosphate biosynthetic process
CEQ50_RS14270	COG2104	thiamine diphosphate biosynthetic process
CEQ50_RS14275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEQ50_RS14280	COG0352	thiamine-phosphate diphosphorylase activity
CEQ50_RS14360	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CEQ50_RS14365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEQ50_RS14370	COG1739	Uncharacterized protein family UPF0029
CEQ50_RS14380	COG0183	Belongs to the thiolase family
CEQ50_RS14385	COG0583	DNA-binding transcription factor activity
CEQ50_RS14390	COG2814	Major facilitator Superfamily
CEQ50_RS14400	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CEQ50_RS14405	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEQ50_RS14410	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEQ50_RS14415	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEQ50_RS14420	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEQ50_RS14425	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEQ50_RS14440	COG3312	ion transport
CEQ50_RS14445	COG1475	DNA binding
CEQ50_RS14450	COG1192	Involved in chromosome partitioning
CEQ50_RS14460	COG0445	tRNA wobble uridine modification
CEQ50_RS14490	COG2084	Dehydrogenase
CEQ50_RS14495	COG0814	amino acid
CEQ50_RS14525	COG0583	DNA-binding transcription factor activity
CEQ50_RS14530	COG2910	NAD(P)H-binding
CEQ50_RS14540	COG3304	Inner membrane component domain
CEQ50_RS14560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEQ50_RS14565	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CEQ50_RS14585	COG0363	glucosamine-6-phosphate deaminase activity
CEQ50_RS14595	COG0739	heme binding
CEQ50_RS14600	COG2213	PTS system mannitol-specific
CEQ50_RS14600	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_RS14605	COG0246	Mannitol dehydrogenase
CEQ50_RS14610	COG3722	fumarate hydratase activity
CEQ50_RS14620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CEQ50_RS14625	COG1301	dicarboxylic acid transport
CEQ50_RS14630	COG2259	Doxx family
CEQ50_RS14655	COG1846	Transcriptional regulator
CEQ50_RS14665	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CEQ50_RS14670	COG3046	protein related to deoxyribodipyrimidine photolyase
CEQ50_RS14675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEQ50_RS14680	COG0842	Transport permease protein
CEQ50_RS14685	COG1131	(ABC) transporter
CEQ50_RS14700	COG3842	ATPase activity
CEQ50_RS14710	COG1175	transmembrane transport
CEQ50_RS14730	COG0513	Belongs to the DEAD box helicase family
CEQ50_RS14735	COG0251	oxidation-reduction process
CEQ50_RS14740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ50_RS14750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEQ50_RS14755	COG1328	CTP reductase activity
CEQ50_RS14765	COG2130	NADP-dependent
CEQ50_RS14770	COG1309	transcriptional regulator
CEQ50_RS14785	COG0745	RESPONSE REGULATOR receiver
CEQ50_RS14795	COG0564	pseudouridine synthase activity
CEQ50_RS14855	COG3829	transcription factor binding
CEQ50_RS14880	COG3501	Rhs element vgr protein
CEQ50_RS14935	COG0471	metal ion transport
CEQ50_RS14940	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CEQ50_RS14950	COG2188	Transcriptional regulator
CEQ50_RS14955	COG1131	(ABC) transporter
CEQ50_RS14965	COG0840	transmembrane signaling receptor activity
CEQ50_RS14995	COG0671	phosphoesterase, PA-phosphatase related
CEQ50_RS15005	COG1132	(ABC) transporter
CEQ50_RS15025	COG3623	hexulose-6-phosphate isomerase
CEQ50_RS15030	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CEQ50_RS15035	COG0561	phosphatase activity
CEQ50_RS15070	COG4580	involved in the transport of maltose and maltodextrins
CEQ50_RS15080	COG0366	Alpha amylase catalytic
CEQ50_RS15090	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CEQ50_RS15100	COG1999	signal sequence binding
CEQ50_RS15115	COG0786	glutamate:sodium symporter activity
CEQ50_RS15140	COG1566	PFAM secretion protein HlyD family protein
CEQ50_RS15165	COG0813	purine-nucleoside phosphorylase activity
CEQ50_RS15170	COG3272	Protein of unknown function (DUF1722)
CEQ50_RS15175	COG0789	Transcriptional regulator
CEQ50_RS15180	COG0415	Belongs to the DNA photolyase family
CEQ50_RS15185	COG1376	ErfK ybiS ycfS ynhG family protein
CEQ50_RS15185	COG1388	LysM domain
CEQ50_RS15195	COG0513	Belongs to the DEAD box helicase family
CEQ50_RS15225	COG2267	carboxylic ester hydrolase activity
CEQ50_RS15235	COG0366	Alpha amylase catalytic
CEQ50_RS15240	COG4989	oxidoreductase activity
CEQ50_RS15250	COG0577	efflux transmembrane transporter activity
CEQ50_RS15250	COG1136	(ABC) transporter
CEQ50_RS15255	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEQ50_RS15270	COG2972	Histidine kinase
CEQ50_RS15270	COG0745	RESPONSE REGULATOR receiver
CEQ50_RS15275	COG3279	Response regulator of the LytR AlgR family
CEQ50_RS15280	COG2203	Gaf domain
CEQ50_RS15280	COG3706	GGDEF domain
CEQ50_RS15280	COG4251	negative regulation of phosphorylation
CEQ50_RS15280	COG5001	Diguanylate cyclase
CEQ50_RS15290	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CEQ50_RS15300	COG3437	response regulator, receiver
CEQ50_RS15305	COG4999	Histidine kinase
CEQ50_RS15305	COG3437	response regulator, receiver
CEQ50_RS15305	COG3850	Histidine kinase
CEQ50_RS15305	COG2205	protein histidine kinase activity
CEQ50_RS15315	COG0531	amino acid
CEQ50_RS15330	COG1151	hydroxylamine reductase activity
CEQ50_RS15335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEQ50_RS15345	COG5002	protein histidine kinase activity
CEQ50_RS15345	COG2205	protein histidine kinase activity
CEQ50_RS15345	COG0784	Response regulator, receiver
CEQ50_RS15365	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEQ50_RS15375	COG1609	Transcriptional regulator
CEQ50_RS15380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_RS15400	COG0673	inositol 2-dehydrogenase activity
CEQ50_RS15405	COG1765	OsmC-like protein
CEQ50_RS15410	COG0110	maltose O-acetyltransferase activity
CEQ50_RS15425	COG0583	DNA-binding transcription factor activity
CEQ50_RS15435	COG0583	DNA-binding transcription factor activity
CEQ50_RS15440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEQ50_RS15445	COG3186	Phenylalanine-4-hydroxylase
CEQ50_RS15450	COG2154	pterin-4-alpha-carbinolamine dehydratase
CEQ50_RS15455	COG0840	transmembrane signaling receptor activity
CEQ50_RS15460	COG0534	Mate efflux family protein
CEQ50_RS15465	COG2207	Transcriptional regulator
CEQ50_RS15470	COG3437	response regulator, receiver
CEQ50_RS15470	COG0784	Response regulator, receiver
CEQ50_RS15480	COG4191	Histidine kinase
CEQ50_RS15480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ50_RS15490	COG2814	Major facilitator Superfamily
CEQ50_RS15500	COG0443	Heat shock 70 kDa protein
CEQ50_RS15515	COG3240	lipase activity
CEQ50_RS15525	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CEQ50_RS15530	COG5380	lipid catabolic process
CEQ50_RS15560	COG4607	ABC-type enterochelin transport system periplasmic component
CEQ50_RS15565	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEQ50_RS15570	COG4605	iron ion homeostasis
CEQ50_RS15575	COG4604	ABC transporter, ATP-binding protein
CEQ50_RS15580	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEQ50_RS15585	COG3385	transposase activity
CEQ50_RS15595	COG2153	protein acetylation
CEQ50_RS15600	COG0697	spore germination
CEQ50_RS15605	COG0387	Pfam Sodium calcium exchanger
CEQ50_RS15610	COG0861	Integral membrane protein TerC family
CEQ50_RS15640	COG0509	glycine decarboxylation via glycine cleavage system
CEQ50_RS15645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEQ50_RS15655	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEQ50_RS15675	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEQ50_RS15685	COG3501	Rhs element vgr protein
CEQ50_RS15755	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CEQ50_RS15755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ50_RS15755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEQ50_RS15760	COG1105	Belongs to the carbohydrate kinase PfkB family
CEQ50_RS15765	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_RS15765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_RS15770	COG1609	Transcriptional regulator
CEQ50_RS15775	COG0420	3'-5' exonuclease activity
CEQ50_RS15780	COG0419	ATPase involved in DNA repair
CEQ50_RS15785	COG2205	protein histidine kinase activity
CEQ50_RS15785	COG0784	Response regulator, receiver
CEQ50_RS15790	COG0156	8-amino-7-oxononanoate synthase activity
CEQ50_RS15800	COG0038	chloride channel
CEQ50_RS15805	COG0523	cobalamin synthesis protein
CEQ50_RS15810	COG1136	(ABC) transporter
CEQ50_RS15815	COG0577	efflux transmembrane transporter activity
CEQ50_RS15815	COG1136	(ABC) transporter
CEQ50_RS15820	COG0577	efflux transmembrane transporter activity
CEQ50_RS15820	COG1136	(ABC) transporter
CEQ50_RS15835	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEQ50_RS15845	COG3675	Pfam Lipase (class 3)
CEQ50_RS15860	COG3730	PTS system glucitol sorbitol-specific
CEQ50_RS15875	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ50_RS15880	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEQ50_RS15885	COG1349	DNA-binding transcription factor activity
CEQ50_RS15890	COG3730	PTS system glucitol sorbitol-specific
CEQ50_RS15915	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEQ50_RS15920	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEQ50_RS15930	COG3005	denitrification pathway
CEQ50_RS15940	COG0243	molybdopterin cofactor binding
CEQ50_RS15950	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEQ50_RS15955	COG3850	Histidine kinase
CEQ50_RS15960	COG2197	response regulator
CEQ50_RS15965	COG3069	C4-dicarboxylate transmembrane transporter activity
CEQ50_RS15990	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEQ50_RS16000	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CEQ50_RS16005	COG0513	Belongs to the DEAD box helicase family
CEQ50_RS16070	COG5002	protein histidine kinase activity
CEQ50_RS16130	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CEQ50_RS16155	COG0384	phenazine biosynthesis protein PhzF
CEQ50_RS16235	COG2433	Pfam Transposase IS66
CEQ50_RS16315	COG1335	isochorismatase
CEQ50_RS16400	COG0653	protein targeting
CEQ50_RS16425	COG4221	oxidoreductase activity
CEQ50_RS16430	COG1280	lysine exporter protein (LysE YggA)
CEQ50_RS16600	COG3041	Addiction module toxin RelE StbE family
CEQ50_RS16660	COG0110	maltose O-acetyltransferase activity
CEQ50_RS16870	COG0242	peptide deformylase activity
CEQ50_RS16890	COG4977	sequence-specific DNA binding
CEQ50_RS16950	COG0346	lactoylglutathione lyase activity
CEQ50_RS16960	COG1187	pseudouridine synthase activity
CEQ50_RS16975	COG0110	maltose O-acetyltransferase activity
CEQ50_RS17020	COG0724	RNA recognition motif
CEQ50_RS17035	COG1192	Involved in chromosome partitioning
CEQ50_RS17055	COG3040	lipid binding
CEQ50_RS17070	COG2433	Pfam Transposase IS66
CEQ50_RS17125	COG0653	protein targeting
CEQ50_RS17185	COG0346	lactoylglutathione lyase activity
CEQ50_RS17230	COG0724	RNA recognition motif
CEQ50_RS17320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ50_RS17330	COG0110	maltose O-acetyltransferase activity
CEQ50_RS17380	COG1028	Short-chain dehydrogenase reductase Sdr
CEQ50_RS17550	COG0023	Translation Initiation Factor
CEQ50_RS17565	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEQ50_RS17575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ50_RS17575	COG0045	succinate-CoA ligase (ADP-forming) activity
CEQ50_RS17575	COG1042	CoA-binding domain protein
CEQ50_RS17580	COG0583	DNA-binding transcription factor activity
CEQ50_RS17600	COG3140	Belongs to the UPF0181 family
CEQ50_RS17615	COG0745	RESPONSE REGULATOR receiver
CEQ50_RS17625	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CEQ50_RS17630	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CEQ50_RS17645	COG3706	GGDEF domain
CEQ50_RS17650	COG1278	Cold shock
CEQ50_RS17660	COG0840	transmembrane signaling receptor activity
CEQ50_RS17675	COG2501	S4 domain
CEQ50_RS17680	COG0625	glutathione transferase activity
CEQ50_RS17695	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEQ50_RS17700	COG0488	(ABC) transporter
CEQ50_RS17715	COG2050	protein possibly involved in aromatic compounds catabolism
CEQ50_RS17725	COG2824	Alkylphosphonate utilization operon protein PhnA
CEQ50_RS17735	COG0861	Integral membrane protein TerC family
CEQ50_RS17740	COG0737	Belongs to the 5'-nucleotidase family
CEQ50_RS17745	COG3593	DNA synthesis involved in DNA repair
CEQ50_RS17755	COG0583	DNA-binding transcription factor activity
CEQ50_RS17760	COG2116	formate transmembrane transporter activity
CEQ50_RS17770	COG3104	oligopeptide transport
CEQ50_RS17780	COG2188	Transcriptional regulator
CEQ50_RS17785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEQ50_RS17790	COG1011	Hydrolase
CEQ50_RS17795	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CEQ50_RS17805	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CEQ50_RS17810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEQ50_RS17815	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CEQ50_RS17820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ50_RS17820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEQ50_RS17825	COG0302	gtp cyclohydrolase
CEQ50_RS17830	COG0303	'Molybdopterin
CEQ50_RS17835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEQ50_RS17840	COG2897	thiosulfate sulfurtransferase activity
CEQ50_RS17860	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEQ50_RS17875	COG0545	Peptidyl-prolyl cis-trans isomerase
CEQ50_RS17880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEQ50_RS17885	COG0840	transmembrane signaling receptor activity
CEQ50_RS17890	COG2353	YceI-like domain
CEQ50_RS17895	COG3038	cytochrome b561
CEQ50_RS17905	COG3706	GGDEF domain
CEQ50_RS17905	COG2203	Gaf domain
CEQ50_RS17905	COG4251	negative regulation of phosphorylation
CEQ50_RS17905	COG5001	Diguanylate cyclase
CEQ50_RS17910	COG4172	Belongs to the ABC transporter superfamily
CEQ50_RS17915	COG4239	(ABC) transporter, permease
CEQ50_RS17920	COG4174	ABC transporter (Permease)
CEQ50_RS17925	COG4166	transmembrane transport
CEQ50_RS17940	COG0189	ligase activity
CEQ50_RS17940	COG4067	protein conserved in archaea
CEQ50_RS17950	COG0602	queuosine metabolic process
CEQ50_RS17955	COG1328	CTP reductase activity
CEQ50_RS17960	COG3706	GGDEF domain
CEQ50_RS18005	COG3300	MHYT domain
CEQ50_RS18005	COG5001	Diguanylate cyclase
CEQ50_RS18010	COG4191	Histidine kinase
CEQ50_RS18015	COG3852	Histidine kinase
CEQ50_RS18040	COG5001	Diguanylate cyclase
CEQ50_RS18040	COG2203	Gaf domain
CEQ50_RS18040	COG4251	negative regulation of phosphorylation
CEQ50_RS18040	COG3706	GGDEF domain
CEQ50_RS18050	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CEQ50_RS18055	COG4149	molybdate abc transporter
CEQ50_RS18060	COG0725	ABC transporter, periplasmic molybdate-binding protein
CEQ50_RS18065	COG1492	cobalamin metabolic process
CEQ50_RS18070	COG3111	PFAM Bacterial OB fold (BOF) protein
CEQ50_RS18085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEQ50_RS18095	COG2207	Transcriptional regulator
CEQ50_RS18100	COG1979	alcohol dehydrogenase
CEQ50_RS18125	COG2271	Major facilitator Superfamily
CEQ50_RS18130	COG0469	pyruvate kinase activity
CEQ50_RS18135	COG2198	Histidine kinase
CEQ50_RS18135	COG2205	protein histidine kinase activity
CEQ50_RS18135	COG0784	Response regulator, receiver
CEQ50_RS18140	COG1879	ABC-type sugar transport system periplasmic component
CEQ50_RS18145	COG1803	Methylglyoxal synthase
CEQ50_RS18150	COG0210	DNA helicase
CEQ50_RS18155	COG1289	transmembrane transporter activity
CEQ50_RS18185	COG5002	protein histidine kinase activity
CEQ50_RS18185	COG0784	Response regulator, receiver
CEQ50_RS18200	COG2827	Endonuclease containing a URI domain
CEQ50_RS18205	COG3132	Protein of unknown function, DUF480
CEQ50_RS18225	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEQ50_RS18230	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEQ50_RS18235	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEQ50_RS18240	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CEQ50_RS18245	COG0247	lactate metabolic process
CEQ50_RS18250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEQ50_RS18255	COG3118	belongs to the thioredoxin family
CEQ50_RS18275	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEQ50_RS18295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEQ50_RS18315	COG2433	Pfam Transposase IS66
CEQ50_RS18355	COG4176	ABC-type proline glycine betaine transport system permease component
CEQ50_RS18360	COG4175	Glycine betaine
CEQ50_RS18360	COG0517	IMP dehydrogenase activity
CEQ50_RS18375	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CEQ50_RS18390	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CEQ50_RS18400	COG0513	Belongs to the DEAD box helicase family
CEQ50_RS18405	COG0814	amino acid
CEQ50_RS18415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEQ50_RS18420	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CEQ50_RS18430	COG1984	allophanate hydrolase subunit 2
CEQ50_RS18440	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CEQ50_RS18445	COG4181	ATPase activity
CEQ50_RS18455	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEQ50_RS18460	COG5001	Diguanylate cyclase
CEQ50_RS18460	COG1716	ATPase activity
CEQ50_RS18470	COG0484	heat shock protein binding
CEQ50_RS18490	COG0784	Response regulator, receiver
CEQ50_RS18490	COG3437	response regulator, receiver
CEQ50_RS18505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ50_RS18510	COG5001	Diguanylate cyclase
CEQ50_RS18510	COG3300	MHYT domain
CEQ50_RS18530	COG0010	Belongs to the arginase family
CEQ50_RS18535	COG1166	arginine decarboxylase activity
CEQ50_RS18550	COG4176	ABC-type proline glycine betaine transport system permease component
CEQ50_RS18555	COG2113	Glycine betaine
CEQ50_RS18575	COG0527	aspartate kinase activity
CEQ50_RS18580	COG0662	Cupin 2, conserved barrel domain protein
CEQ50_RS18585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CEQ50_RS18590	COG0456	acetyltransferase
CEQ50_RS18600	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEQ50_RS18605	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CEQ50_RS18640	COG0366	Alpha amylase catalytic
CEQ50_RS18660	COG0714	Associated with various cellular activities
CEQ50_RS18680	COG2304	oxidoreductase activity
CEQ50_RS18695	COG3706	GGDEF domain
CEQ50_RS18710	COG3530	Putative quorum-sensing-regulated virulence factor
CEQ50_RS18715	COG1368	sulfuric ester hydrolase activity
CEQ50_RS18725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEQ50_RS18730	COG1063	alcohol dehydrogenase
CEQ50_RS18735	COG0156	8-amino-7-oxononanoate synthase activity
CEQ50_RS18745	COG0346	lactoylglutathione lyase activity
CEQ50_RS18760	COG2197	response regulator
CEQ50_RS18765	COG3851	Histidine kinase
CEQ50_RS18770	COG2271	Major facilitator Superfamily
CEQ50_RS18780	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CEQ50_RS18805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEQ50_RS18810	COG0640	Transcriptional regulator
CEQ50_RS18815	COG0798	PFAM Bile acid sodium symporter
CEQ50_RS18820	COG0640	Transcriptional regulator
CEQ50_RS18825	COG0659	secondary active sulfate transmembrane transporter activity
CEQ50_RS18830	COG0589	response to stress
CEQ50_RS18855	COG4977	sequence-specific DNA binding
CEQ50_RS18855	COG1917	Cupin 2, conserved barrel domain protein
CEQ50_RS18860	COG4771	TonB-dependent receptor
CEQ50_RS18865	COG2814	Major facilitator Superfamily
CEQ50_RS18870	COG2226	methyltransferase
CEQ50_RS18870	COG3433	isochorismatase activity
CEQ50_RS18870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEQ50_RS18895	COG1021	2,3-dihydroxybenzoate-AMP ligase
CEQ50_RS18900	COG1132	(ABC) transporter
CEQ50_RS18905	COG1132	(ABC) transporter
CEQ50_RS18910	COG0516	GMP reductase activity
CEQ50_RS18915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEQ50_RS18940	COG1278	Cold shock
CEQ50_RS18945	COG4681	YaeQ
CEQ50_RS18950	COG1017	nitric oxide dioxygenase activity
CEQ50_RS18950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEQ50_RS18955	COG3604	Transcriptional regulator
CEQ50_RS18965	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEQ50_RS18970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEQ50_RS18975	COG3217	Mosc domain protein beta barrel domain protein
CEQ50_RS18975	COG0633	Ferredoxin
CEQ50_RS18980	COG0418	dihydroorotase activity
CEQ50_RS18985	COG3385	transposase activity
CEQ50_RS18990	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEQ50_RS18995	COG2354	Protein conserved in bacteria
CEQ50_RS19000	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CEQ50_RS19020	COG2199	diguanylate cyclase activity
CEQ50_RS19025	COG1349	DNA-binding transcription factor activity
CEQ50_RS19050	COG3833	ABC-type maltose transport systems, permease component
CEQ50_RS19055	COG1175	transmembrane transport
CEQ50_RS19070	COG3842	ATPase activity
CEQ50_RS19080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEQ50_RS19085	COG0784	Response regulator, receiver
CEQ50_RS19085	COG0835	chemotaxis
CEQ50_RS19090	COG2315	Protein conserved in bacteria
CEQ50_RS19095	COG3706	GGDEF domain
CEQ50_RS19130	COG5001	Diguanylate cyclase
CEQ50_RS19140	COG1741	Belongs to the pirin family
CEQ50_RS19150	COG3123	guanosine phosphorylase activity
CEQ50_RS19160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEQ50_RS19170	COG0765	amino acid transport
CEQ50_RS19175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEQ50_RS19180	COG0765	amino acid transport
CEQ50_RS19185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEQ50_RS19205	COG0179	Fumarylacetoacetate (FAA) hydrolase
CEQ50_RS19215	COG0697	spore germination
CEQ50_RS19235	COG2814	Major facilitator Superfamily
CEQ50_RS19240	COG0583	DNA-binding transcription factor activity
CEQ50_RS19245	COG5001	Diguanylate cyclase
CEQ50_RS19250	COG0739	heme binding
CEQ50_RS19260	COG0659	secondary active sulfate transmembrane transporter activity
CEQ50_RS19265	COG3314	Sporulation integral membrane protein YlbJ
CEQ50_RS19280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEQ50_RS19285	COG0581	inorganic phosphate transmembrane transporter activity
CEQ50_RS19290	COG0573	inorganic phosphate transmembrane transporter activity
CEQ50_RS19295	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEQ50_RS19305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEQ50_RS19310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEQ50_RS19325	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CEQ50_RS19335	COG0393	Putative heavy-metal-binding
CEQ50_RS19345	COG3047	cAMP biosynthetic process
CEQ50_RS19360	COG2271	Major facilitator Superfamily
CEQ50_RS19365	COG0584	glycerophosphoryl diester phosphodiesterase
CEQ50_RS19375	COG3527	Alpha-acetolactate decarboxylase
CEQ50_RS19400	COG0640	Transcriptional regulator
CEQ50_RS19405	COG0583	DNA-binding transcription factor activity
CEQ50_RS19410	COG1620	l-lactate permease
CEQ50_RS19430	COG1881	PFAM PEBP family protein
CEQ50_RS19445	COG1230	cation diffusion facilitator family transporter
CEQ50_RS19450	COG3122	Protein conserved in bacteria
CEQ50_RS19495	COG0583	DNA-binding transcription factor activity
CEQ50_RS19505	COG1609	Transcriptional regulator
CEQ50_RS19510	COG1472	Belongs to the glycosyl hydrolase 3 family
CEQ50_RS19515	COG3842	ATPase activity
CEQ50_RS19520	COG0395	ABC-type sugar transport system, permease component
CEQ50_RS19535	COG1609	Transcriptional regulator
CEQ50_RS19540	COG4580	involved in the transport of maltose and maltodextrins
CEQ50_RS19560	COG2211	Major facilitator Superfamily
CEQ50_RS19570	COG1067	ATP-dependent peptidase activity
CEQ50_RS19580	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEQ50_RS19585	COG0363	glucosamine-6-phosphate deaminase activity
CEQ50_RS19595	COG0583	DNA-binding transcription factor activity
CEQ50_RS19610	COG1609	Transcriptional regulator
CEQ50_RS19615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEQ50_RS19620	COG1879	ABC-type sugar transport system periplasmic component
CEQ50_RS19625	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEQ50_RS19630	COG1129	ABC transporter
CEQ50_RS19635	COG1869	D-ribose catabolic process
CEQ50_RS19650	COG3409	Peptidoglycan-binding domain 1 protein
CEQ50_RS19650	COG3501	Rhs element vgr protein
CEQ50_RS19660	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CEQ50_RS19665	COG1640	4-alpha-glucanotransferase
CEQ50_RS19670	COG0058	SHG alpha-glucan phosphorylase activity
CEQ50_RS19675	COG2909	trisaccharide binding
CEQ50_RS19700	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEQ50_RS19720	COG0840	transmembrane signaling receptor activity
CEQ50_RS19755	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CEQ50_RS19765	COG0259	pyridoxamine-phosphate oxidase activity
CEQ50_RS19815	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CEQ50_RS19820	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CEQ50_RS19825	COG0840	transmembrane signaling receptor activity
CEQ50_RS19835	COG0835	chemotaxis
CEQ50_RS19840	COG2198	Histidine kinase
CEQ50_RS19840	COG0643	Histidine kinase
CEQ50_RS19855	COG1444	tRNA N-acetyltransferase activity
CEQ50_RS19860	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine