A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 Gene3D G3DSA:2.40.37.10 265 417 9.9E-47 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 5 412 1.8E-167 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 229 242 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 380 402 4.5E-29 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 165 174 4.5E-29 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 76 93 4.5E-29 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 300 318 4.5E-29 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 58 76 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 16 413 40.905 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 31 370 9.0E-26 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 SUPERFAMILY SSF50621 259 414 1.9E-52 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 Gene3D G3DSA:3.20.20.10 35 264 3.4E-54 T 28-03-2018 IPR029066 PLP-binding barrel A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 SUPERFAMILY SSF51419 27 284 1.57E-79 T 28-03-2018 IPR029066 PLP-binding barrel A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 58 76 1.4E-26 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 370 383 1.4E-26 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 191 204 1.4E-26 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 272 291 1.4E-26 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 78 90 1.4E-26 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 A6A12_RS00390 a174a5ac38d07fbe8199bc02d21e0d86 417 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 36 282 1.8E-72 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 A6A12_RS13340 cdfb481eadbe88e63930a23e6337d58b 362 PIRSF PIRSF000390 1 362 1.2E-107 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A6A12_RS13340 cdfb481eadbe88e63930a23e6337d58b 362 Gene3D G3DSA:3.90.1150.10 235 362 2.5E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS13340 cdfb481eadbe88e63930a23e6337d58b 362 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 9 358 2.0E-109 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A6A12_RS13340 cdfb481eadbe88e63930a23e6337d58b 362 SUPERFAMILY SSF53383 5 361 9.04E-99 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS13340 cdfb481eadbe88e63930a23e6337d58b 362 Gene3D G3DSA:3.40.640.10 2 234 9.1E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS06510 09a37e0f7abf4c5576b1e5d9300c0d33 365 Gene3D G3DSA:1.10.3720.10 29 365 7.0E-41 T 28-03-2018 A6A12_RS06510 09a37e0f7abf4c5576b1e5d9300c0d33 365 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 155 251 4.0E-22 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A6A12_RS06510 09a37e0f7abf4c5576b1e5d9300c0d33 365 SUPERFAMILY SSF161098 155 346 1.02E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS06510 09a37e0f7abf4c5576b1e5d9300c0d33 365 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 173 358 1.0E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS10585 3ad7283a57d0618b5def64cf0e104d9d 377 PRINTS PR00207 Flagellin signature 111 134 5.1E-27 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A6A12_RS10585 3ad7283a57d0618b5def64cf0e104d9d 377 PRINTS PR00207 Flagellin signature 76 95 5.1E-27 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A6A12_RS10585 3ad7283a57d0618b5def64cf0e104d9d 377 PRINTS PR00207 Flagellin signature 37 54 5.1E-27 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A6A12_RS10585 3ad7283a57d0618b5def64cf0e104d9d 377 Gene3D G3DSA:1.20.1330.10 40 349 1.6E-67 T 28-03-2018 A6A12_RS10585 3ad7283a57d0618b5def64cf0e104d9d 377 SUPERFAMILY SSF64518 1 376 1.27E-93 T 28-03-2018 A6A12_RS10585 3ad7283a57d0618b5def64cf0e104d9d 377 Pfam PF07196 Flagellin hook IN motif 196 248 3.1E-10 T 28-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 A6A12_RS10585 3ad7283a57d0618b5def64cf0e104d9d 377 Pfam PF00700 Bacterial flagellin C-terminal helical region 292 376 2.2E-24 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A6A12_RS10585 3ad7283a57d0618b5def64cf0e104d9d 377 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 5.6E-42 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A6A12_RS11345 0967285926739ef3c16fd0f7f2c10468 183 Pfam PF01814 Hemerythrin HHE cation binding domain 2 135 5.4E-14 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 A6A12_RS11345 0967285926739ef3c16fd0f7f2c10468 183 Gene3D G3DSA:1.20.120.520 1 157 2.5E-16 T 28-03-2018 A6A12_RS03405 c571c97757abb494b5264b5f72ad02b6 699 SUPERFAMILY SSF56024 500 683 6.28E-68 T 28-03-2018 A6A12_RS03405 c571c97757abb494b5264b5f72ad02b6 699 Gene3D G3DSA:1.20.58.310 9 108 1.0E-33 T 28-03-2018 A6A12_RS03405 c571c97757abb494b5264b5f72ad02b6 699 Gene3D G3DSA:3.30.870.10 500 686 2.8E-31 T 28-03-2018 A6A12_RS03405 c571c97757abb494b5264b5f72ad02b6 699 Gene3D G3DSA:3.30.870.10 319 499 1.8E-20 T 28-03-2018 A6A12_RS03405 c571c97757abb494b5264b5f72ad02b6 699 Gene3D G3DSA:3.30.1840.10 109 307 2.8E-57 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 A6A12_RS03405 c571c97757abb494b5264b5f72ad02b6 699 SUPERFAMILY SSF143724 107 313 6.47E-64 T 28-03-2018 A6A12_RS03405 c571c97757abb494b5264b5f72ad02b6 699 Pfam PF13090 Polyphosphate kinase C-terminal domain 331 676 5.5E-144 T 28-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 A6A12_RS03405 c571c97757abb494b5264b5f72ad02b6 699 SUPERFAMILY SSF56024 315 496 1.0E-53 T 28-03-2018 A6A12_RS03405 c571c97757abb494b5264b5f72ad02b6 699 PIRSF PIRSF015589 1 694 2.3E-250 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A6A12_RS03405 c571c97757abb494b5264b5f72ad02b6 699 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 7 677 2.6E-263 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A6A12_RS03405 c571c97757abb494b5264b5f72ad02b6 699 Pfam PF13089 Polyphosphate kinase N-terminal domain 7 109 6.2E-31 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 A6A12_RS03405 c571c97757abb494b5264b5f72ad02b6 699 Pfam PF02503 Polyphosphate kinase middle domain 119 320 9.7E-48 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 A6A12_RS03405 c571c97757abb494b5264b5f72ad02b6 699 Hamap MF_00347 Polyphosphate kinase [ppk]. 5 681 27.002 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 A6A12_RS03405 c571c97757abb494b5264b5f72ad02b6 699 SUPERFAMILY SSF140356 4 104 3.66E-33 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 SUPERFAMILY SSF55729 466 585 9.24E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 Pfam PF14698 Argininosuccinate lyase C-terminal 364 431 3.6E-25 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 TIGRFAM TIGR00838 argH: argininosuccinate lyase 3 456 2.4E-204 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 SUPERFAMILY SSF48557 3 456 1.05E-140 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 Gene3D G3DSA:1.20.200.10 108 375 3.6E-93 T 28-03-2018 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 Gene3D G3DSA:1.10.40.30 376 433 5.3E-27 T 28-03-2018 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 6.5E-28 T 28-03-2018 IPR000362 Fumarate lyase family A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 6.5E-28 T 28-03-2018 IPR000362 Fumarate lyase family A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 6.5E-28 T 28-03-2018 IPR000362 Fumarate lyase family A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 6.5E-28 T 28-03-2018 IPR000362 Fumarate lyase family A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 8.5E-68 T 28-03-2018 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 8.5E-68 T 28-03-2018 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 8.5E-68 T 28-03-2018 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 8.5E-68 T 28-03-2018 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 8.5E-68 T 28-03-2018 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 8.5E-68 T 28-03-2018 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 Pfam PF00583 Acetyltransferase (GNAT) family 500 570 2.2E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 PIRSF PIRSF036456 1 624 0.0 T 28-03-2018 IPR011244 Bifunctional argininosuccinate lyase/acetyltransferase GO:0004056|GO:0005737|GO:0006526|GO:0016746 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 Pfam PF00206 Lyase 6 301 4.8E-89 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 454 40.742 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 Gene3D G3DSA:3.40.630.30 464 607 8.3E-17 T 28-03-2018 A6A12_RS12735 0cefe442a8a1807e0126c2a851d27658 624 Gene3D G3DSA:1.10.275.10 2 107 1.0E-31 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal A6A12_RS04425 e50ff5fff981410f5cc7b1b7a335b112 383 Pfam PF01494 FAD binding domain 150 332 4.9E-20 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 A6A12_RS04425 e50ff5fff981410f5cc7b1b7a335b112 383 Gene3D G3DSA:3.50.50.60 1 355 2.1E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS04425 e50ff5fff981410f5cc7b1b7a335b112 383 SUPERFAMILY SSF51905 264 375 6.19E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS04425 e50ff5fff981410f5cc7b1b7a335b112 383 SUPERFAMILY SSF51905 3 175 6.19E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS04425 e50ff5fff981410f5cc7b1b7a335b112 383 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 5 382 9.1E-110 T 28-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 A6A12_RS04425 e50ff5fff981410f5cc7b1b7a335b112 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 4.9E-18 T 28-03-2018 A6A12_RS04425 e50ff5fff981410f5cc7b1b7a335b112 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 4.9E-18 T 28-03-2018 A6A12_RS04425 e50ff5fff981410f5cc7b1b7a335b112 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 4.9E-18 T 28-03-2018 A6A12_RS04425 e50ff5fff981410f5cc7b1b7a335b112 383 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 4.9E-18 T 28-03-2018 A6A12_RS00010 1467645bb9617b7cc34fb27c1477b6ab 366 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 245 365 2.9E-38 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS00010 1467645bb9617b7cc34fb27c1477b6ab 366 Gene3D G3DSA:3.10.150.10 124 247 5.0E-34 T 28-03-2018 A6A12_RS00010 1467645bb9617b7cc34fb27c1477b6ab 366 SUPERFAMILY SSF55979 126 244 5.1E-29 T 28-03-2018 A6A12_RS00010 1467645bb9617b7cc34fb27c1477b6ab 366 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 366 1.4E-108 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS00010 1467645bb9617b7cc34fb27c1477b6ab 366 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 243 8.2E-36 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS00010 1467645bb9617b7cc34fb27c1477b6ab 366 PIRSF PIRSF000804 1 366 3.0E-117 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS00010 1467645bb9617b7cc34fb27c1477b6ab 366 Gene3D G3DSA:3.10.150.10 248 366 5.5E-27 T 28-03-2018 A6A12_RS00010 1467645bb9617b7cc34fb27c1477b6ab 366 SUPERFAMILY SSF55979 1 118 1.84E-28 T 28-03-2018 A6A12_RS00010 1467645bb9617b7cc34fb27c1477b6ab 366 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 119 1.8E-37 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS00010 1467645bb9617b7cc34fb27c1477b6ab 366 Gene3D G3DSA:3.10.150.10 1 123 1.1E-27 T 28-03-2018 A6A12_RS00010 1467645bb9617b7cc34fb27c1477b6ab 366 SMART SM00480 17 362 2.9E-144 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS00010 1467645bb9617b7cc34fb27c1477b6ab 366 SUPERFAMILY SSF55979 245 366 6.73E-36 T 28-03-2018 A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 PRINTS PR00934 X-His dipeptidase (M25) signature 367 385 2.9E-88 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 PRINTS PR00934 X-His dipeptidase (M25) signature 210 227 2.9E-88 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 PRINTS PR00934 X-His dipeptidase (M25) signature 454 476 2.9E-88 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 PRINTS PR00934 X-His dipeptidase (M25) signature 432 448 2.9E-88 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 PRINTS PR00934 X-His dipeptidase (M25) signature 105 123 2.9E-88 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 PRINTS PR00934 X-His dipeptidase (M25) signature 255 274 2.9E-88 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 PRINTS PR00934 X-His dipeptidase (M25) signature 84 103 2.9E-88 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 PRINTS PR00934 X-His dipeptidase (M25) signature 139 156 2.9E-88 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 PRINTS PR00934 X-His dipeptidase (M25) signature 163 181 2.9E-88 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 Gene3D G3DSA:3.40.630.10 2 490 5.6E-49 T 28-03-2018 A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 Pfam PF01546 Peptidase family M20/M25/M40 77 472 2.7E-21 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 Pfam PF07687 Peptidase dimerisation domain 213 295 8.8E-9 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 PIRSF PIRSF016599 5 489 9.5E-213 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 SUPERFAMILY SSF53187 401 486 1.07E-59 T 28-03-2018 A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 SUPERFAMILY SSF53187 16 186 1.07E-59 T 28-03-2018 A6A12_RS11000 c6721ef479e3552e11b9e86017efa8bf 490 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 14 486 1.1E-178 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 A6A12_RS03465 e99152365dda3df7c09e642c6cd72d21 376 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 5 371 7.5E-186 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A6A12_RS03465 e99152365dda3df7c09e642c6cd72d21 376 Pfam PF01702 Queuine tRNA-ribosyltransferase 128 363 2.4E-94 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A6A12_RS03465 e99152365dda3df7c09e642c6cd72d21 376 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 5 370 7.3E-177 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A6A12_RS03465 e99152365dda3df7c09e642c6cd72d21 376 Gene3D G3DSA:3.20.20.105 1 371 1.4E-158 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A6A12_RS03465 e99152365dda3df7c09e642c6cd72d21 376 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 3 366 56.733 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A6A12_RS03465 e99152365dda3df7c09e642c6cd72d21 376 SUPERFAMILY SSF51713 3 366 5.75E-162 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A6A12_RS04355 9c35ed44460e912b8e76385857ff606e 260 Gene3D G3DSA:2.40.40.10 56 169 2.2E-26 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A6A12_RS04355 9c35ed44460e912b8e76385857ff606e 260 Gene3D G3DSA:3.30.70.1070 185 256 4.1E-7 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A6A12_RS04355 9c35ed44460e912b8e76385857ff606e 260 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 79 183 1.0E-45 T 28-03-2018 IPR012997 Rare lipoprotein A A6A12_RS04355 9c35ed44460e912b8e76385857ff606e 260 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 19 169 25.236 T 28-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 A6A12_RS04355 9c35ed44460e912b8e76385857ff606e 260 Pfam PF03330 Lytic transglycolase 77 165 4.1E-27 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A6A12_RS04355 9c35ed44460e912b8e76385857ff606e 260 Pfam PF05036 Sporulation related domain 185 253 8.9E-8 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A6A12_RS04355 9c35ed44460e912b8e76385857ff606e 260 SUPERFAMILY SSF50685 76 165 5.55E-9 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A6A12_RS04355 9c35ed44460e912b8e76385857ff606e 260 SUPERFAMILY SSF110997 182 255 1.19E-11 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A6A12_RS12940 6f19ce236d28ddab9cfb88f6938b03c6 80 Pfam PF06005 Cell division protein ZapB 1 77 7.9E-25 T 28-03-2018 IPR009252 Cell division protein ZapB GO:0005737|GO:0043093|GO:0090529 A6A12_RS12940 6f19ce236d28ddab9cfb88f6938b03c6 80 Hamap MF_01196 Cell division protein ZapB [zapB]. 1 79 17.568 T 28-03-2018 IPR009252 Cell division protein ZapB GO:0005737|GO:0043093|GO:0090529 A6A12_RS12940 6f19ce236d28ddab9cfb88f6938b03c6 80 Gene3D G3DSA:1.20.5.370 13 44 8.0E-13 T 28-03-2018 A6A12_RS12940 6f19ce236d28ddab9cfb88f6938b03c6 80 Gene3D G3DSA:1.20.5.370 45 80 4.9E-10 T 28-03-2018 A6A12_RS13245 bc6c16e4a463df6e6f0efc2159987f4a 386 Gene3D G3DSA:1.20.5.70 354 382 1.3E-13 T 28-03-2018 A6A12_RS13245 bc6c16e4a463df6e6f0efc2159987f4a 386 Pfam PF10531 SLBB domain 254 303 6.6E-6 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A6A12_RS13245 bc6c16e4a463df6e6f0efc2159987f4a 386 Pfam PF10531 SLBB domain 172 218 4.5E-9 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A6A12_RS13245 bc6c16e4a463df6e6f0efc2159987f4a 386 Pfam PF02563 Polysaccharide biosynthesis/export protein 79 163 1.7E-27 T 28-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 A6A12_RS13245 bc6c16e4a463df6e6f0efc2159987f4a 386 Gene3D G3DSA:3.10.560.10 248 352 3.6E-18 T 28-03-2018 A6A12_RS13245 bc6c16e4a463df6e6f0efc2159987f4a 386 Gene3D G3DSA:3.10.560.10 159 247 1.3E-24 T 28-03-2018 A6A12_RS13245 bc6c16e4a463df6e6f0efc2159987f4a 386 Gene3D G3DSA:3.30.1950.10 87 158 7.1E-25 T 28-03-2018 A6A12_RS12790 e0b806e3829a4827beca14693a7d5266 324 Gene3D G3DSA:3.30.930.10 4 322 8.7E-68 T 28-03-2018 A6A12_RS12790 e0b806e3829a4827beca14693a7d5266 324 SUPERFAMILY SSF55681 11 321 1.67E-81 T 28-03-2018 A6A12_RS12790 e0b806e3829a4827beca14693a7d5266 324 Hamap MF_00174 Elongation factor P--(R)-beta-lysine ligase [epmA]. 1 324 53.003 T 28-03-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 A6A12_RS12790 e0b806e3829a4827beca14693a7d5266 324 Pfam PF00152 tRNA synthetases class II (D, K and N) 14 320 1.0E-45 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS12790 e0b806e3829a4827beca14693a7d5266 324 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 15 319 5.2E-129 T 28-03-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 136 144 - T 28-03-2018 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 Gene3D G3DSA:1.10.441.10 175 275 1.7E-32 T 28-03-2018 A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 PRINTS PR00714 Phosphomannose isomerase type I signature 233 248 1.1E-66 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 PRINTS PR00714 Phosphomannose isomerase type I signature 91 112 1.1E-66 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 PRINTS PR00714 Phosphomannose isomerase type I signature 249 268 1.1E-66 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 PRINTS PR00714 Phosphomannose isomerase type I signature 15 33 1.1E-66 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 PRINTS PR00714 Phosphomannose isomerase type I signature 136 159 1.1E-66 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 PRINTS PR00714 Phosphomannose isomerase type I signature 43 58 1.1E-66 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 PRINTS PR00714 Phosphomannose isomerase type I signature 287 306 1.1E-66 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 PRINTS PR00714 Phosphomannose isomerase type I signature 268 287 1.1E-66 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 SUPERFAMILY SSF51182 10 392 3.52E-104 T 28-03-2018 IPR011051 RmlC-like cupin domain A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 Gene3D G3DSA:2.60.120.10 16 174 9.5E-50 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 ProSitePatterns PS00966 Phosphomannose isomerase type I signature 2. 268 293 - T 28-03-2018 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 Pfam PF01238 Phosphomannose isomerase type I 13 367 4.4E-84 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 PIRSF PIRSF001480 10 402 1.2E-101 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 Gene3D G3DSA:2.60.120.10 308 402 5.7E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS06295 0023966d85f848b9d25c7c3f650b0bf6 402 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 12 392 1.7E-89 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 A6A12_RS09235 27d74c0dc9d804d9305fd5d4cee0d05d 414 Gene3D G3DSA:3.30.9.10 182 330 1.8E-15 T 28-03-2018 A6A12_RS09235 27d74c0dc9d804d9305fd5d4cee0d05d 414 Pfam PF01494 FAD binding domain 6 164 1.0E-14 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 A6A12_RS09235 27d74c0dc9d804d9305fd5d4cee0d05d 414 SUPERFAMILY SSF51905 285 387 2.77E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS09235 27d74c0dc9d804d9305fd5d4cee0d05d 414 SUPERFAMILY SSF51905 6 175 2.77E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS09235 27d74c0dc9d804d9305fd5d4cee0d05d 414 Gene3D G3DSA:3.50.50.60 5 179 1.3E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS00615 26fd9a66080b12b6311b462b420d72f2 125 Pfam PF07226 Protein of unknown function (DUF1422) 10 118 3.1E-49 T 28-03-2018 IPR009867 Protein of unknown function DUF1422 A6A12_RS00615 26fd9a66080b12b6311b462b420d72f2 125 ProDom PD076479 MEMBRANE INNER YIJD TRANSMEMBRANE Y0323 AAA SIMILAR A ACETYL-COENZYME VV0128 1 116 8.0E-45 T 28-03-2018 IPR009867 Protein of unknown function DUF1422 A6A12_RS02510 1486933879a61707c35d37b3a298507f 592 SUPERFAMILY SSF51230 517 591 4.84E-20 T 28-03-2018 IPR011053 Single hybrid motif A6A12_RS02510 1486933879a61707c35d37b3a298507f 592 SUPERFAMILY SSF89000 297 462 2.28E-51 T 28-03-2018 A6A12_RS02510 1486933879a61707c35d37b3a298507f 592 Pfam PF00682 HMGL-like 6 269 5.2E-57 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A6A12_RS02510 1486933879a61707c35d37b3a298507f 592 Gene3D G3DSA:2.40.50.100 518 592 4.3E-19 T 28-03-2018 A6A12_RS02510 1486933879a61707c35d37b3a298507f 592 Gene3D G3DSA:1.10.10.60 399 453 4.2E-14 T 28-03-2018 A6A12_RS02510 1486933879a61707c35d37b3a298507f 592 Pfam PF00364 Biotin-requiring enzyme 526 590 3.9E-16 T 28-03-2018 IPR000089 Biotin/lipoyl attachment A6A12_RS02510 1486933879a61707c35d37b3a298507f 592 Gene3D G3DSA:3.20.20.70 1 284 3.2E-74 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS02510 1486933879a61707c35d37b3a298507f 592 Pfam PF02436 Conserved carboxylase domain 292 492 9.5E-58 T 28-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A6A12_RS02510 1486933879a61707c35d37b3a298507f 592 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 548 565 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A6A12_RS02510 1486933879a61707c35d37b3a298507f 592 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 7 586 2.0E-264 T 28-03-2018 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 A6A12_RS02510 1486933879a61707c35d37b3a298507f 592 SUPERFAMILY SSF51569 1 300 3.11E-87 T 28-03-2018 A6A12_RS13280 7016cf5f6c23980f40ac398b65c2ae0e 316 Gene3D G3DSA:3.90.25.10 177 316 4.6E-18 T 28-03-2018 A6A12_RS13280 7016cf5f6c23980f40ac398b65c2ae0e 316 Gene3D G3DSA:3.40.50.720 1 176 4.4E-29 T 28-03-2018 A6A12_RS13280 7016cf5f6c23980f40ac398b65c2ae0e 316 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 221 4.2E-30 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A6A12_RS13280 7016cf5f6c23980f40ac398b65c2ae0e 316 SUPERFAMILY SSF51735 2 314 5.55E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS04775 88dd0ace135ddba55079712cf2919309 166 Pfam PF01967 MoaC family 15 150 3.3E-56 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 A6A12_RS04775 88dd0ace135ddba55079712cf2919309 166 SUPERFAMILY SSF55040 11 155 6.67E-61 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 A6A12_RS04775 88dd0ace135ddba55079712cf2919309 166 Gene3D G3DSA:3.30.70.640 2 158 1.7E-68 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 A6A12_RS04775 88dd0ace135ddba55079712cf2919309 166 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 152 1.4E-71 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 A6A12_RS04775 88dd0ace135ddba55079712cf2919309 166 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 158 35.791 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 A6A12_RS14225 d067a6fbdd54f40f0048ccee64c0abfa 614 SUPERFAMILY SSF53092 23 148 3.49E-19 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal A6A12_RS14225 d067a6fbdd54f40f0048ccee64c0abfa 614 Gene3D G3DSA:3.90.230.10 318 571 1.5E-61 T 28-03-2018 A6A12_RS14225 d067a6fbdd54f40f0048ccee64c0abfa 614 Pfam PF01321 Creatinase/Prolidase N-terminal domain 26 155 2.6E-22 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 A6A12_RS14225 d067a6fbdd54f40f0048ccee64c0abfa 614 Pfam PF16189 Creatinase/Prolidase N-terminal domain 166 324 7.4E-36 T 28-03-2018 A6A12_RS14225 d067a6fbdd54f40f0048ccee64c0abfa 614 SUPERFAMILY SSF55920 321 577 1.15E-55 T 28-03-2018 IPR000994 Peptidase M24 A6A12_RS14225 d067a6fbdd54f40f0048ccee64c0abfa 614 Pfam PF16188 C-terminal region of peptidase_M24 552 610 2.7E-21 T 28-03-2018 IPR032416 Peptidase M24, C-terminal domain A6A12_RS14225 d067a6fbdd54f40f0048ccee64c0abfa 614 Pfam PF00557 Metallopeptidase family M24 328 542 1.3E-42 T 28-03-2018 IPR000994 Peptidase M24 A6A12_RS14225 d067a6fbdd54f40f0048ccee64c0abfa 614 Gene3D G3DSA:3.40.350.10 174 314 1.6E-14 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A6A12_RS14225 d067a6fbdd54f40f0048ccee64c0abfa 614 Gene3D G3DSA:3.40.350.10 18 164 1.4E-41 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A6A12_RS04300 1232da7eb3250257119ad4c535f1ac86 734 Pfam PF02706 Chain length determinant protein 16 105 6.0E-12 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 A6A12_RS04300 1232da7eb3250257119ad4c535f1ac86 734 Gene3D G3DSA:3.40.50.300 508 734 2.6E-32 T 28-03-2018 A6A12_RS04300 1232da7eb3250257119ad4c535f1ac86 734 SUPERFAMILY SSF52540 541 730 7.27E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS04300 1232da7eb3250257119ad4c535f1ac86 734 Gene3D G3DSA:3.30.1890.10 45 450 4.0E-29 T 28-03-2018 A6A12_RS04300 1232da7eb3250257119ad4c535f1ac86 734 Pfam PF13614 AAA domain 553 671 1.3E-10 T 28-03-2018 IPR025669 AAA domain A6A12_RS04300 1232da7eb3250257119ad4c535f1ac86 734 Pfam PF13807 G-rich domain on putative tyrosine kinase 401 472 4.7E-9 T 28-03-2018 IPR032807 Tyrosine kinase, G-rich domain A6A12_RS04300 1232da7eb3250257119ad4c535f1ac86 734 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 523 726 2.7E-46 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 A6A12_RS00915 005e0e5370523c0206968b4926002971 275 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 10 260 5.0E-107 T 28-03-2018 IPR006240 3(2),5 -bisphosphate nucleotidase, bacterial GO:0000287|GO:0016020 KEGG: 00920+3.1.3.7 A6A12_RS00915 005e0e5370523c0206968b4926002971 275 SUPERFAMILY SSF56655 7 272 8.51E-78 T 28-03-2018 A6A12_RS00915 005e0e5370523c0206968b4926002971 275 Gene3D G3DSA:3.40.190.80 164 273 4.4E-28 T 28-03-2018 A6A12_RS00915 005e0e5370523c0206968b4926002971 275 Gene3D G3DSA:3.30.540.10 5 163 3.8E-42 T 28-03-2018 A6A12_RS00915 005e0e5370523c0206968b4926002971 275 Pfam PF00459 Inositol monophosphatase family 15 253 5.1E-52 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A6A12_RS00915 005e0e5370523c0206968b4926002971 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 65 81 1.1E-5 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A6A12_RS00915 005e0e5370523c0206968b4926002971 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 89 105 1.1E-5 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A6A12_RS00915 005e0e5370523c0206968b4926002971 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 43 63 1.1E-5 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A6A12_RS04635 c714b3fbd037bf90691afa6a57bd4449 211 SMART SM00478 38 185 1.4E-50 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A6A12_RS04635 c714b3fbd037bf90691afa6a57bd4449 211 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 168 1.0E-18 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A6A12_RS04635 c714b3fbd037bf90691afa6a57bd4449 211 Pfam PF00633 Helix-hairpin-helix motif 100 127 4.1E-8 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A6A12_RS04635 c714b3fbd037bf90691afa6a57bd4449 211 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 A6A12_RS04635 c714b3fbd037bf90691afa6a57bd4449 211 TIGRFAM TIGR01083 nth: endonuclease III 5 194 4.6E-88 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A6A12_RS04635 c714b3fbd037bf90691afa6a57bd4449 211 PIRSF PIRSF001435 1 210 6.3E-51 T 28-03-2018 A6A12_RS04635 c714b3fbd037bf90691afa6a57bd4449 211 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A6A12_RS04635 c714b3fbd037bf90691afa6a57bd4449 211 Gene3D G3DSA:1.10.340.30 25 116 5.4E-23 T 28-03-2018 A6A12_RS04635 c714b3fbd037bf90691afa6a57bd4449 211 SMART SM00525 186 206 3.7E-5 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A6A12_RS04635 c714b3fbd037bf90691afa6a57bd4449 211 Hamap MF_00942 Endonuclease III [nth]. 1 209 37.609 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A6A12_RS04635 c714b3fbd037bf90691afa6a57bd4449 211 SUPERFAMILY SSF48150 6 208 2.04E-70 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A6A12_RS04635 c714b3fbd037bf90691afa6a57bd4449 211 Gene3D G3DSA:1.10.1670.10 117 210 6.0E-30 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A6A12_RS04635 c714b3fbd037bf90691afa6a57bd4449 211 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 7.6E-5 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A6A12_RS05490 9a04cf5605f8263bd47cb553ceb732f6 676 Pfam PF00990 Diguanylate cyclase, GGDEF domain 527 667 6.4E-40 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS05490 9a04cf5605f8263bd47cb553ceb732f6 676 Gene3D G3DSA:1.25.40.10 49 411 5.0E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS05490 9a04cf5605f8263bd47cb553ceb732f6 676 SUPERFAMILY SSF48452 142 297 5.03E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS05490 9a04cf5605f8263bd47cb553ceb732f6 676 Gene3D G3DSA:3.30.70.270 451 672 2.1E-51 T 28-03-2018 A6A12_RS05490 9a04cf5605f8263bd47cb553ceb732f6 676 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 530 670 1.4E-43 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS05490 9a04cf5605f8263bd47cb553ceb732f6 676 SMART SM00267 452 672 4.0E-38 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS05490 9a04cf5605f8263bd47cb553ceb732f6 676 SUPERFAMILY SSF55073 532 669 2.04E-38 T 28-03-2018 IPR029787 Nucleotide cyclase A6A12_RS12390 a7cce014599a851da5a362b0f6ba5fe0 129 Gene3D G3DSA:3.30.420.80 3 129 8.1E-45 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A6A12_RS12390 a7cce014599a851da5a362b0f6ba5fe0 129 SUPERFAMILY SSF53137 14 129 6.54E-48 T 28-03-2018 A6A12_RS12390 a7cce014599a851da5a362b0f6ba5fe0 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 32.753 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A6A12_RS12390 a7cce014599a851da5a362b0f6ba5fe0 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 4.2E-55 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12390 a7cce014599a851da5a362b0f6ba5fe0 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site A6A12_RS12390 a7cce014599a851da5a362b0f6ba5fe0 129 Pfam PF00411 Ribosomal protein S11 19 128 1.5E-52 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A6A12_RS12390 a7cce014599a851da5a362b0f6ba5fe0 129 PIRSF PIRSF002131 1 129 1.5E-52 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 205 517 7.8E-156 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 SUPERFAMILY SSF54810 397 517 3.92E-51 T 28-03-2018 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 10 197 3.0E-83 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 Pfam PF00117 Glutamine amidotransferase class-I 12 192 1.7E-41 T 28-03-2018 IPR017926 Glutamine amidotransferase A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 51 65 7.3E-7 T 28-03-2018 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 7.3E-7 T 28-03-2018 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 10 24 7.3E-7 T 28-03-2018 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 1.3E-7 T 28-03-2018 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 1.3E-7 T 28-03-2018 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 1.3E-7 T 28-03-2018 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 Pfam PF00958 GMP synthase C terminal domain 425 516 1.1E-43 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 Gene3D G3DSA:3.30.300.10 406 517 6.6E-53 T 28-03-2018 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 Pfam PF02540 NAD synthase 213 284 4.6E-8 T 28-03-2018 IPR022310 NAD/GMP synthase A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 Gene3D G3DSA:3.40.50.880 1 191 1.2E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 SUPERFAMILY SSF52317 9 200 2.45E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 SUPERFAMILY SSF52402 189 412 1.48E-60 T 28-03-2018 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 7 517 56.322 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 Gene3D G3DSA:3.40.50.620 192 405 6.4E-43 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 PRINTS PR00097 Anthranilate synthase component II signature 54 63 3.8E-6 T 28-03-2018 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 PRINTS PR00097 Anthranilate synthase component II signature 81 92 3.8E-6 T 28-03-2018 A6A12_RS03595 7283111cb54125efc66dff19f581eb3a 517 PRINTS PR00097 Anthranilate synthase component II signature 169 182 3.8E-6 T 28-03-2018 A6A12_RS00930 85bec154e82978f8b032d6dbf0e5c002 233 Pfam PF00156 Phosphoribosyl transferase domain 136 230 7.7E-12 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A6A12_RS00930 85bec154e82978f8b032d6dbf0e5c002 233 Gene3D G3DSA:3.40.50.2020 83 233 8.5E-23 T 28-03-2018 A6A12_RS00930 85bec154e82978f8b032d6dbf0e5c002 233 SUPERFAMILY SSF53271 54 231 9.96E-37 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A6A12_RS02540 4014a47dbe4c4a267da3ae8602ca0e8f 172 Gene3D G3DSA:3.30.1360.80 3 161 5.0E-62 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A6A12_RS02540 4014a47dbe4c4a267da3ae8602ca0e8f 172 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 7.2E-50 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A6A12_RS02540 4014a47dbe4c4a267da3ae8602ca0e8f 172 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 77 95 7.2E-50 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A6A12_RS02540 4014a47dbe4c4a267da3ae8602ca0e8f 172 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 7.2E-50 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A6A12_RS02540 4014a47dbe4c4a267da3ae8602ca0e8f 172 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 121 140 7.2E-50 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A6A12_RS02540 4014a47dbe4c4a267da3ae8602ca0e8f 172 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 7.2E-50 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A6A12_RS02540 4014a47dbe4c4a267da3ae8602ca0e8f 172 SUPERFAMILY SSF63411 4 162 1.19E-63 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A6A12_RS02540 4014a47dbe4c4a267da3ae8602ca0e8f 172 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 159 34.2 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A6A12_RS02540 4014a47dbe4c4a267da3ae8602ca0e8f 172 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 9 154 9.0E-75 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A6A12_RS02540 4014a47dbe4c4a267da3ae8602ca0e8f 172 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 154 1.3E-59 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A6A12_RS02540 4014a47dbe4c4a267da3ae8602ca0e8f 172 PIRSF PIRSF006160 1 162 8.2E-65 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 2.1E-14 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 2.1E-14 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 96 110 2.1E-14 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 97 106 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 SUPERFAMILY SSF55957 358 445 1.44E-22 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 SUPERFAMILY SSF53738 4 182 3.3E-49 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 367 4.2E-31 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 SUPERFAMILY SSF53738 157 257 3.92E-30 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 Gene3D G3DSA:3.40.120.10 271 374 3.2E-27 T 28-03-2018 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 SUPERFAMILY SSF53738 259 366 3.85E-29 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 Gene3D G3DSA:3.40.120.10 157 270 1.7E-33 T 28-03-2018 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 Gene3D G3DSA:3.40.120.10 4 155 1.4E-49 T 28-03-2018 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 5 136 4.9E-46 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 442 7.5E-12 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 Gene3D G3DSA:3.30.310.50 375 446 3.3E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 8 443 4.9E-203 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 255 1.3E-19 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02940 e7844c07eecb4202e5fb0ef454e02955 446 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 4 445 47.168 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS00040 cc3c9be6f4c8e9ddb9c2b8fe0a34dadd 415 Gene3D G3DSA:3.40.640.10 69 291 6.5E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS00040 cc3c9be6f4c8e9ddb9c2b8fe0a34dadd 415 SUPERFAMILY SSF53383 13 408 6.81E-59 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS00040 cc3c9be6f4c8e9ddb9c2b8fe0a34dadd 415 Gene3D G3DSA:3.90.1150.10 292 411 2.4E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS00040 cc3c9be6f4c8e9ddb9c2b8fe0a34dadd 415 Pfam PF00155 Aminotransferase class I and II 67 402 1.6E-25 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A6A12_RS07300 a567a390eb11fce2ba1df7ff78fbd0a8 284 SUPERFAMILY SSF103481 184 280 3.34E-10 T 28-03-2018 A6A12_RS07300 a567a390eb11fce2ba1df7ff78fbd0a8 284 SUPERFAMILY SSF103481 45 133 3.66E-5 T 28-03-2018 A6A12_RS07300 a567a390eb11fce2ba1df7ff78fbd0a8 284 Pfam PF00892 EamA-like transporter family 146 276 1.3E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A6A12_RS00355 6163a7634539337885f22663ba8757c8 393 Gene3D G3DSA:1.25.40.10 155 302 3.5E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS00355 6163a7634539337885f22663ba8757c8 393 Gene3D G3DSA:1.25.40.10 79 154 0.13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS00355 6163a7634539337885f22663ba8757c8 393 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 2 386 9.6E-114 T 28-03-2018 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 A6A12_RS00355 6163a7634539337885f22663ba8757c8 393 SUPERFAMILY SSF48452 84 233 5.48E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS00355 6163a7634539337885f22663ba8757c8 393 Pfam PF07219 HemY protein N-terminus 26 132 3.6E-26 T 28-03-2018 IPR010817 HemY, N-terminal A6A12_RS00355 6163a7634539337885f22663ba8757c8 393 SUPERFAMILY SSF48452 311 389 2.02E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS00355 6163a7634539337885f22663ba8757c8 393 Gene3D G3DSA:1.25.40.10 339 391 4.6E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS00355 6163a7634539337885f22663ba8757c8 393 Pfam PF07719 Tetratricopeptide repeat 327 356 4.1E-5 T 28-03-2018 IPR013105 Tetratricopeptide repeat 2 A6A12_RS00355 6163a7634539337885f22663ba8757c8 393 Gene3D G3DSA:1.25.40.10 303 338 3.4E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 31 137 2.0E-9 T 28-03-2018 IPR000014 PAS domain A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 149 259 2.5E-14 T 28-03-2018 IPR000014 PAS domain A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 Gene3D G3DSA:3.40.50.10600 135 259 1.0E-26 T 28-03-2018 A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 Gene3D G3DSA:3.40.50.10600 12 134 1.8E-28 T 28-03-2018 A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 SMART SM00086 212 254 0.032 T 28-03-2018 IPR001610 PAC motif A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 SMART SM00086 92 134 0.076 T 28-03-2018 IPR001610 PAC motif A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 SUPERFAMILY SSF55785 152 254 3.38E-20 T 28-03-2018 IPR000014 PAS domain A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 SMART SM00091 17 87 14.0 T 28-03-2018 IPR000014 PAS domain A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 SMART SM00091 139 207 1.6 T 28-03-2018 IPR000014 PAS domain A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 SUPERFAMILY SSF55785 30 131 6.46E-23 T 28-03-2018 IPR000014 PAS domain A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 288 429 5.1E-37 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 Gene3D G3DSA:1.10.287.950 260 431 6.3E-42 T 28-03-2018 A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 SUPERFAMILY SSF58104 245 429 6.15E-48 T 28-03-2018 A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 SMART SM00283 243 431 1.4E-18 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 Pfam PF13426 PAS domain 33 133 4.1E-12 T 28-03-2018 IPR000014 PAS domain A6A12_RS08115 883486a775571094ec0e07b5eb2c5c32 431 Pfam PF13426 PAS domain 155 253 2.4E-9 T 28-03-2018 IPR000014 PAS domain A6A12_RS09175 c4fd76137957dae2111b0ca7481ca772 321 Gene3D G3DSA:3.40.50.2300 26 150 1.4E-21 T 28-03-2018 A6A12_RS09175 c4fd76137957dae2111b0ca7481ca772 321 Gene3D G3DSA:3.40.50.2300 151 287 1.5E-17 T 28-03-2018 A6A12_RS09175 c4fd76137957dae2111b0ca7481ca772 321 Pfam PF04392 ABC transporter substrate binding protein 29 321 6.7E-118 T 28-03-2018 IPR007487 ABC transporter, substrate-binding protein A6A12_RS09175 c4fd76137957dae2111b0ca7481ca772 321 SUPERFAMILY SSF53822 43 275 1.44E-18 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A6A12_RS00790 82e0dc47f112231d1e6b6f0f3ce0bc6c 857 SUPERFAMILY SSF158472 376 425 1.31E-6 T 28-03-2018 A6A12_RS00790 82e0dc47f112231d1e6b6f0f3ce0bc6c 857 Pfam PF00990 Diguanylate cyclase, GGDEF domain 435 582 3.4E-31 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS00790 82e0dc47f112231d1e6b6f0f3ce0bc6c 857 SMART SM00052 598 846 3.8E-104 T 28-03-2018 IPR001633 EAL domain A6A12_RS00790 82e0dc47f112231d1e6b6f0f3ce0bc6c 857 SMART SM00304 375 428 0.0019 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS00790 82e0dc47f112231d1e6b6f0f3ce0bc6c 857 Gene3D G3DSA:3.30.70.270 428 594 3.2E-37 T 28-03-2018 A6A12_RS00790 82e0dc47f112231d1e6b6f0f3ce0bc6c 857 SUPERFAMILY SSF141868 605 850 3.4E-82 T 28-03-2018 IPR001633 EAL domain A6A12_RS00790 82e0dc47f112231d1e6b6f0f3ce0bc6c 857 Gene3D G3DSA:3.30.450.20 213 354 4.6E-15 T 28-03-2018 A6A12_RS00790 82e0dc47f112231d1e6b6f0f3ce0bc6c 857 Gene3D G3DSA:3.20.20.450 595 850 8.6E-90 T 28-03-2018 IPR001633 EAL domain A6A12_RS00790 82e0dc47f112231d1e6b6f0f3ce0bc6c 857 Pfam PF02743 Cache domain 129 293 8.1E-18 T 28-03-2018 IPR033479 Double Cache domain 1 A6A12_RS00790 82e0dc47f112231d1e6b6f0f3ce0bc6c 857 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 432 582 2.0E-24 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS00790 82e0dc47f112231d1e6b6f0f3ce0bc6c 857 Pfam PF00563 EAL domain 605 840 7.3E-70 T 28-03-2018 IPR001633 EAL domain A6A12_RS00790 82e0dc47f112231d1e6b6f0f3ce0bc6c 857 SMART SM00267 423 588 4.6E-36 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS00790 82e0dc47f112231d1e6b6f0f3ce0bc6c 857 SUPERFAMILY SSF55073 439 590 2.98E-31 T 28-03-2018 IPR029787 Nucleotide cyclase A6A12_RS00790 82e0dc47f112231d1e6b6f0f3ce0bc6c 857 Gene3D G3DSA:3.30.450.20 87 212 5.6E-14 T 28-03-2018 A6A12_RS10740 b9fce84aa655cd540f05ac4a083e0890 325 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 71 223 8.7E-48 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A6A12_RS10740 b9fce84aa655cd540f05ac4a083e0890 325 Pfam PF00849 RNA pseudouridylate synthase 67 193 2.2E-13 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS10740 b9fce84aa655cd540f05ac4a083e0890 325 SMART SM00363 7 64 1.1E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS10740 b9fce84aa655cd540f05ac4a083e0890 325 Gene3D G3DSA:3.10.290.10 4 64 1.0E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS10740 b9fce84aa655cd540f05ac4a083e0890 325 Gene3D G3DSA:3.30.70.580 65 145 2.1E-15 T 28-03-2018 A6A12_RS10740 b9fce84aa655cd540f05ac4a083e0890 325 SUPERFAMILY SSF55120 66 227 2.76E-38 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS10740 b9fce84aa655cd540f05ac4a083e0890 325 Pfam PF01479 S4 domain 8 52 2.7E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS10740 b9fce84aa655cd540f05ac4a083e0890 325 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 102 116 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A6A12_RS10740 b9fce84aa655cd540f05ac4a083e0890 325 Gene3D G3DSA:3.30.70.1560 146 210 2.5E-26 T 28-03-2018 A6A12_RS10740 b9fce84aa655cd540f05ac4a083e0890 325 SUPERFAMILY SSF55174 6 98 3.36E-15 T 28-03-2018 A6A12_RS07545 b6e1023e1136482cec6ef40191bbaafc 268 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 189 266 2.9E-22 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 A6A12_RS07545 b6e1023e1136482cec6ef40191bbaafc 268 SUPERFAMILY SSF74653 188 264 2.75E-22 T 28-03-2018 A6A12_RS07545 b6e1023e1136482cec6ef40191bbaafc 268 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 190 266 4.8E-22 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 A6A12_RS07545 b6e1023e1136482cec6ef40191bbaafc 268 Gene3D G3DSA:3.30.1150.10 78 268 1.4E-18 T 28-03-2018 A6A12_RS09655 58e129cdd4b4cd45ac30e693d34754ed 328 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 20 203 6.0E-57 T 28-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS09655 58e129cdd4b4cd45ac30e693d34754ed 328 Pfam PF13177 DNA polymerase III, delta subunit 20 172 3.1E-40 T 28-03-2018 A6A12_RS09655 58e129cdd4b4cd45ac30e693d34754ed 328 SUPERFAMILY SSF52540 11 207 3.4E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09655 58e129cdd4b4cd45ac30e693d34754ed 328 SUPERFAMILY SSF48019 214 326 1.0E-18 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A6A12_RS09655 58e129cdd4b4cd45ac30e693d34754ed 328 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 213 322 2.5E-24 T 28-03-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS09655 58e129cdd4b4cd45ac30e693d34754ed 328 Gene3D G3DSA:3.40.50.300 19 169 2.5E-20 T 28-03-2018 A6A12_RS09655 58e129cdd4b4cd45ac30e693d34754ed 328 Gene3D G3DSA:1.20.272.10 216 324 2.0E-4 T 28-03-2018 A6A12_RS10240 4be3814d43200f4f0d8e60934520803a 488 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 161 174 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A6A12_RS10240 4be3814d43200f4f0d8e60934520803a 488 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 223 238 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A6A12_RS10240 4be3814d43200f4f0d8e60934520803a 488 Gene3D G3DSA:1.10.8.60 310 379 2.7E-20 T 28-03-2018 A6A12_RS10240 4be3814d43200f4f0d8e60934520803a 488 SMART SM00382 157 304 1.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS10240 4be3814d43200f4f0d8e60934520803a 488 Gene3D G3DSA:1.10.10.60 380 488 4.1E-15 T 28-03-2018 A6A12_RS10240 4be3814d43200f4f0d8e60934520803a 488 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 450 467 6.8E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS10240 4be3814d43200f4f0d8e60934520803a 488 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 467 487 6.8E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS10240 4be3814d43200f4f0d8e60934520803a 488 Pfam PF00158 Sigma-54 interaction domain 137 304 3.4E-73 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A6A12_RS10240 4be3814d43200f4f0d8e60934520803a 488 SUPERFAMILY SSF52540 137 378 3.34E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS10240 4be3814d43200f4f0d8e60934520803a 488 Gene3D G3DSA:3.40.50.300 133 309 6.9E-27 T 28-03-2018 A6A12_RS10240 4be3814d43200f4f0d8e60934520803a 488 SUPERFAMILY SSF46689 349 392 2.02E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS10240 4be3814d43200f4f0d8e60934520803a 488 SUPERFAMILY SSF46689 434 486 2.02E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS10240 4be3814d43200f4f0d8e60934520803a 488 Pfam PF02954 Bacterial regulatory protein, Fis family 444 484 1.2E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS10240 4be3814d43200f4f0d8e60934520803a 488 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 349 358 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A6A12_RS10240 4be3814d43200f4f0d8e60934520803a 488 Pfam PF06490 Flagellar regulatory protein FleQ 6 115 5.1E-27 T 28-03-2018 IPR010518 Flagellar regulatory FleQ A6A12_RS03955 f064f40dbabe3e26bc629561a820c183 178 Pfam PF14437 MafB19-like deaminase 15 161 1.7E-34 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A6A12_RS03955 f064f40dbabe3e26bc629561a820c183 178 SUPERFAMILY SSF53927 8 162 6.69E-56 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A6A12_RS03955 f064f40dbabe3e26bc629561a820c183 178 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 65 102 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A6A12_RS03955 f064f40dbabe3e26bc629561a820c183 178 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 20 161 45.792 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 A6A12_RS03955 f064f40dbabe3e26bc629561a820c183 178 Gene3D G3DSA:3.40.140.10 7 171 9.5E-52 T 28-03-2018 A6A12_RS14030 757d9644d29d6972166fe6d2eb5382d9 162 Pfam PF10675 Protein of unknown function (DUF2489) 14 145 1.6E-44 T 28-03-2018 IPR019617 Domain of unknown function DUF2489 A6A12_RS03410 fab5572ffd46625a4906048e8d16e174 733 SUPERFAMILY SSF161098 579 665 1.53E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS03410 fab5572ffd46625a4906048e8d16e174 733 SUPERFAMILY SSF161098 429 496 1.53E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS03410 fab5572ffd46625a4906048e8d16e174 733 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 451 727 1.7E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS03410 fab5572ffd46625a4906048e8d16e174 733 Gene3D G3DSA:2.130.10.10 173 427 0.0022 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A6A12_RS03410 fab5572ffd46625a4906048e8d16e174 733 SUPERFAMILY SSF69322 64 377 6.02E-8 T 28-03-2018 A6A12_RS03410 fab5572ffd46625a4906048e8d16e174 733 Gene3D G3DSA:2.120.10.30 47 148 0.062 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like A6A12_RS03410 fab5572ffd46625a4906048e8d16e174 733 Gene3D G3DSA:1.10.3720.10 428 729 1.4E-33 T 28-03-2018 A6A12_RS12400 756d9a7dbdd6c76983597e7873ac5986 37 SUPERFAMILY SSF57840 1 37 1.02E-16 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12400 756d9a7dbdd6c76983597e7873ac5986 37 Pfam PF00444 Ribosomal protein L36 1 37 9.4E-19 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12400 756d9a7dbdd6c76983597e7873ac5986 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 3.0E-9 T 28-03-2018 A6A12_RS12400 756d9a7dbdd6c76983597e7873ac5986 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12400 756d9a7dbdd6c76983597e7873ac5986 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.137 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12400 756d9a7dbdd6c76983597e7873ac5986 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 4.0E-23 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS07100 1bf9a8a19f4de3a02faec7d2a0a5f7c1 639 Pfam PF09863 Uncharacterized protein conserved in bacteria (DUF2090) 327 636 1.3E-140 T 28-03-2018 IPR018659 Protein of unknown function DUF2090 A6A12_RS07100 1bf9a8a19f4de3a02faec7d2a0a5f7c1 639 Gene3D G3DSA:3.40.1190.20 8 337 1.6E-64 T 28-03-2018 IPR029056 Ribokinase-like A6A12_RS07100 1bf9a8a19f4de3a02faec7d2a0a5f7c1 639 Gene3D G3DSA:3.20.20.70 347 639 4.2E-67 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS07100 1bf9a8a19f4de3a02faec7d2a0a5f7c1 639 SUPERFAMILY SSF53613 7 331 1.03E-73 T 28-03-2018 IPR029056 Ribokinase-like A6A12_RS07100 1bf9a8a19f4de3a02faec7d2a0a5f7c1 639 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 276 289 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A6A12_RS07100 1bf9a8a19f4de3a02faec7d2a0a5f7c1 639 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 8 332 9.4E-126 T 28-03-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 A6A12_RS07100 1bf9a8a19f4de3a02faec7d2a0a5f7c1 639 Pfam PF00294 pfkB family carbohydrate kinase 9 324 6.1E-48 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB A6A12_RS11305 65b43497f526a52b0a9589b0045da614 407 Gene3D G3DSA:3.40.720.10 269 406 1.7E-15 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A6A12_RS11305 65b43497f526a52b0a9589b0045da614 407 TIGRFAM TIGR01696 deoB: phosphopentomutase 3 403 6.2E-178 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A6A12_RS11305 65b43497f526a52b0a9589b0045da614 407 SUPERFAMILY SSF143856 118 234 2.09E-47 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A6A12_RS11305 65b43497f526a52b0a9589b0045da614 407 SUPERFAMILY SSF53649 1 115 5.89E-69 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A6A12_RS11305 65b43497f526a52b0a9589b0045da614 407 SUPERFAMILY SSF53649 236 406 5.89E-69 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A6A12_RS11305 65b43497f526a52b0a9589b0045da614 407 PIRSF PIRSF001491 1 407 2.2E-161 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A6A12_RS11305 65b43497f526a52b0a9589b0045da614 407 Pfam PF01676 Metalloenzyme superfamily 2 397 3.4E-44 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A6A12_RS11305 65b43497f526a52b0a9589b0045da614 407 Gene3D G3DSA:3.30.70.1250 117 234 3.0E-48 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A6A12_RS11305 65b43497f526a52b0a9589b0045da614 407 Hamap MF_00740 Phosphopentomutase [deoB]. 1 406 53.704 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 A6A12_RS06255 ae6c8249e5a0cc94542d663abdbbda66 99 Hamap MF_00805 Citrate lyase acyl carrier protein [citD]. 1 99 24.837 T 28-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 A6A12_RS06255 ae6c8249e5a0cc94542d663abdbbda66 99 TIGRFAM TIGR01608 citD: citrate lyase acyl carrier protein 1 91 1.5E-32 T 28-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 A6A12_RS06255 ae6c8249e5a0cc94542d663abdbbda66 99 Pfam PF06857 Malonate decarboxylase delta subunit (MdcD) 5 86 1.6E-31 T 28-03-2018 IPR023439 Malonate decarboxylase/citrate lyase acyl carrier protein A6A12_RS06255 ae6c8249e5a0cc94542d663abdbbda66 99 PIRSF PIRSF002736 1 97 3.2E-35 T 28-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 A6A12_RS06255 ae6c8249e5a0cc94542d663abdbbda66 99 ProDom PD015389 LYASE CITRATE ACYL CARRIER GAMMA CHAIN CITD PRECURSOR SIGNAL DIRECT 10 73 7.0E-14 T 28-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 A6A12_RS06335 6875b81a013def6ebe10d21cf73eb559 160 Gene3D G3DSA:3.30.420.130 1 94 2.6E-18 T 28-03-2018 A6A12_RS06335 6875b81a013def6ebe10d21cf73eb559 160 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 88 3.9E-14 T 28-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A6A12_RS06335 6875b81a013def6ebe10d21cf73eb559 160 SUPERFAMILY SSF53146 1 90 1.23E-19 T 28-03-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A6A12_RS07790 19533b0430cb3931691a928e74e5e008 384 SUPERFAMILY SSF52440 18 122 3.16E-6 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A6A12_RS07790 19533b0430cb3931691a928e74e5e008 384 Pfam PF07478 D-ala D-ala ligase C-terminus 136 355 8.8E-21 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS07790 19533b0430cb3931691a928e74e5e008 384 Gene3D G3DSA:3.30.470.20 205 378 5.1E-18 T 28-03-2018 A6A12_RS07790 19533b0430cb3931691a928e74e5e008 384 SUPERFAMILY SSF56059 128 351 1.32E-22 T 28-03-2018 A6A12_RS07790 19533b0430cb3931691a928e74e5e008 384 Gene3D G3DSA:3.40.50.20 8 128 5.8E-4 T 28-03-2018 A6A12_RS07790 19533b0430cb3931691a928e74e5e008 384 Gene3D G3DSA:3.30.1490.20 129 204 1.2E-7 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A6A12_RS03605 d24e5f1a66b68fe7585f76cebfdd4e10 562 Gene3D G3DSA:1.10.530.10 84 342 3.2E-55 T 28-03-2018 A6A12_RS03605 d24e5f1a66b68fe7585f76cebfdd4e10 562 Pfam PF00182 Chitinase class I 105 327 4.6E-32 T 28-03-2018 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A6A12_RS03605 d24e5f1a66b68fe7585f76cebfdd4e10 562 Gene3D G3DSA:2.10.10.20 502 562 0.0027 T 28-03-2018 A6A12_RS03605 d24e5f1a66b68fe7585f76cebfdd4e10 562 SUPERFAMILY SSF53955 86 349 3.37E-53 T 28-03-2018 IPR023346 Lysozyme-like domain A6A12_RS03605 d24e5f1a66b68fe7585f76cebfdd4e10 562 Gene3D G3DSA:2.10.10.20 431 479 3.0E-15 T 28-03-2018 A6A12_RS03605 d24e5f1a66b68fe7585f76cebfdd4e10 562 SUPERFAMILY SSF51055 432 477 1.83E-14 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A6A12_RS03605 d24e5f1a66b68fe7585f76cebfdd4e10 562 SMART SM00495 514 559 2.4 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A6A12_RS03605 d24e5f1a66b68fe7585f76cebfdd4e10 562 SMART SM00495 435 477 2.3E-16 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A6A12_RS05220 c8a0ec540ff8ce83b70f05638fd8f9b2 226 Gene3D G3DSA:3.40.50.300 4 223 1.6E-52 T 28-03-2018 A6A12_RS05220 c8a0ec540ff8ce83b70f05638fd8f9b2 226 Hamap MF_00238 Cytidylate kinase [cmk]. 6 224 35.218 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A6A12_RS05220 c8a0ec540ff8ce83b70f05638fd8f9b2 226 TIGRFAM TIGR00017 cmk: cytidylate kinase 6 219 5.2E-87 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A6A12_RS05220 c8a0ec540ff8ce83b70f05638fd8f9b2 226 SUPERFAMILY SSF52540 6 223 1.78E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05220 c8a0ec540ff8ce83b70f05638fd8f9b2 226 Pfam PF02224 Cytidylate kinase 8 221 6.6E-80 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A6A12_RS11210 b2bf821911f49a6dfa1aee903498fb37 371 Gene3D G3DSA:3.90.70.10 162 358 3.2E-17 T 28-03-2018 A6A12_RS11210 b2bf821911f49a6dfa1aee903498fb37 371 Pfam PF11814 Peptidase_C39 like family 157 359 1.1E-77 T 28-03-2018 IPR021770 Protein of unknown function DUF3335 A6A12_RS11210 b2bf821911f49a6dfa1aee903498fb37 371 Gene3D G3DSA:3.40.630.30 1 74 2.1E-9 T 28-03-2018 A6A12_RS11210 b2bf821911f49a6dfa1aee903498fb37 371 Gene3D G3DSA:3.40.630.30 75 142 4.6E-18 T 28-03-2018 A6A12_RS11210 b2bf821911f49a6dfa1aee903498fb37 371 SUPERFAMILY SSF55729 2 151 4.15E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS11210 b2bf821911f49a6dfa1aee903498fb37 371 Pfam PF00583 Acetyltransferase (GNAT) family 32 123 2.6E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A6A12_RS12230 26eed6e141d71693d744e4d2a2bc6ac9 175 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 35.82 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A6A12_RS12230 26eed6e141d71693d744e4d2a2bc6ac9 175 SUPERFAMILY SSF50324 3 174 3.92E-65 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A6A12_RS12230 26eed6e141d71693d744e4d2a2bc6ac9 175 Gene3D G3DSA:3.90.80.10 2 175 2.1E-51 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A6A12_RS12230 26eed6e141d71693d744e4d2a2bc6ac9 175 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A6A12_RS12230 26eed6e141d71693d744e4d2a2bc6ac9 175 Pfam PF00719 Inorganic pyrophosphatase 18 173 3.4E-52 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A6A12_RS12915 54dafe374f0ecfc944235771ca58c0f6 425 SMART SM00919 173 409 3.6E-139 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A6A12_RS12915 54dafe374f0ecfc944235771ca58c0f6 425 ProSitePatterns PS00331 Malic enzymes signature. 169 185 - T 28-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 A6A12_RS12915 54dafe374f0ecfc944235771ca58c0f6 425 SUPERFAMILY SSF53223 20 171 1.01E-51 T 28-03-2018 A6A12_RS12915 54dafe374f0ecfc944235771ca58c0f6 425 Pfam PF03949 Malic enzyme, NAD binding domain 175 369 1.5E-25 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A6A12_RS12915 54dafe374f0ecfc944235771ca58c0f6 425 SUPERFAMILY SSF51735 173 418 1.82E-80 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS12915 54dafe374f0ecfc944235771ca58c0f6 425 SMART SM01274 28 161 4.0E-73 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A6A12_RS12915 54dafe374f0ecfc944235771ca58c0f6 425 PIRSF PIRSF000106 49 425 3.2E-72 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A6A12_RS12915 54dafe374f0ecfc944235771ca58c0f6 425 Pfam PF00390 Malic enzyme, N-terminal domain 30 160 2.1E-27 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A6A12_RS12915 54dafe374f0ecfc944235771ca58c0f6 425 Gene3D G3DSA:3.40.50.10380 15 170 4.4E-34 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A6A12_RS12915 54dafe374f0ecfc944235771ca58c0f6 425 Gene3D G3DSA:3.40.50.720 171 425 3.0E-83 T 28-03-2018 A6A12_RS08250 b6578da610b9bb0f4e6d6e9a51fbb428 1021 Gene3D G3DSA:1.10.45.10 531 547 6.9E-6 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A6A12_RS08250 b6578da610b9bb0f4e6d6e9a51fbb428 1021 SUPERFAMILY SSF46548 657 695 1.46E-6 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A6A12_RS08250 b6578da610b9bb0f4e6d6e9a51fbb428 1021 SUPERFAMILY SSF46548 581 627 1.46E-6 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A6A12_RS08250 b6578da610b9bb0f4e6d6e9a51fbb428 1021 Gene3D G3DSA:1.10.45.10 478 530 3.7E-11 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 A6A12_RS08250 b6578da610b9bb0f4e6d6e9a51fbb428 1021 Pfam PF01565 FAD binding domain 62 201 5.0E-35 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A6A12_RS08250 b6578da610b9bb0f4e6d6e9a51fbb428 1021 Gene3D G3DSA:3.30.465.10 117 308 2.7E-44 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A6A12_RS08250 b6578da610b9bb0f4e6d6e9a51fbb428 1021 Pfam PF13183 4Fe-4S dicluster domain 580 691 3.9E-12 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A6A12_RS08250 b6578da610b9bb0f4e6d6e9a51fbb428 1021 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 677 688 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A6A12_RS08250 b6578da610b9bb0f4e6d6e9a51fbb428 1021 Gene3D G3DSA:3.30.43.10 1 116 1.3E-16 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A6A12_RS08250 b6578da610b9bb0f4e6d6e9a51fbb428 1021 Gene3D G3DSA:1.10.1060.10 548 711 1.6E-12 T 28-03-2018 A6A12_RS08250 b6578da610b9bb0f4e6d6e9a51fbb428 1021 SUPERFAMILY SSF56176 24 202 3.11E-51 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A6A12_RS08250 b6578da610b9bb0f4e6d6e9a51fbb428 1021 SUPERFAMILY SSF56176 245 287 3.11E-51 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A6A12_RS08250 b6578da610b9bb0f4e6d6e9a51fbb428 1021 Pfam PF02913 FAD linked oxidases, C-terminal domain 286 544 6.9E-62 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 A6A12_RS08250 b6578da610b9bb0f4e6d6e9a51fbb428 1021 SUPERFAMILY SSF55103 263 547 7.36E-54 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 A6A12_RS06425 050295a6e90c5f33b14f2eaf74c5a084 625 Gene3D G3DSA:3.30.300.30 495 605 6.5E-26 T 28-03-2018 A6A12_RS06425 050295a6e90c5f33b14f2eaf74c5a084 625 Gene3D G3DSA:2.30.38.10 407 494 4.2E-12 T 28-03-2018 A6A12_RS06425 050295a6e90c5f33b14f2eaf74c5a084 625 SUPERFAMILY SSF56801 4 622 2.22E-155 T 28-03-2018 A6A12_RS06425 050295a6e90c5f33b14f2eaf74c5a084 625 Gene3D G3DSA:3.40.50.980 51 242 6.8E-43 T 28-03-2018 A6A12_RS06425 050295a6e90c5f33b14f2eaf74c5a084 625 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 4 56 8.3E-13 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 A6A12_RS06425 050295a6e90c5f33b14f2eaf74c5a084 625 Gene3D G3DSA:3.40.50.980 243 406 3.5E-37 T 28-03-2018 A6A12_RS06425 050295a6e90c5f33b14f2eaf74c5a084 625 ProSitePatterns PS00455 Putative AMP-binding domain signature. 237 248 - T 28-03-2018 IPR020845 AMP-binding, conserved site A6A12_RS06425 050295a6e90c5f33b14f2eaf74c5a084 625 Pfam PF00501 AMP-binding enzyme 66 501 2.3E-83 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A6A12_RS06425 050295a6e90c5f33b14f2eaf74c5a084 625 Pfam PF13193 AMP-binding enzyme C-terminal domain 510 589 1.7E-26 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A6A12_RS03235 30ed6ea232115b0d6902d2fc58b3c8f2 386 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 22 384 2.1E-164 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 A6A12_RS03235 30ed6ea232115b0d6902d2fc58b3c8f2 386 Gene3D G3DSA:3.30.420.40 20 199 1.9E-57 T 28-03-2018 A6A12_RS03235 30ed6ea232115b0d6902d2fc58b3c8f2 386 Gene3D G3DSA:3.30.420.40 225 386 2.9E-25 T 28-03-2018 A6A12_RS03235 30ed6ea232115b0d6902d2fc58b3c8f2 386 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 21 385 41.91 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 A6A12_RS03235 30ed6ea232115b0d6902d2fc58b3c8f2 386 SUPERFAMILY SSF53067 83 128 3.48E-27 T 28-03-2018 A6A12_RS03235 30ed6ea232115b0d6902d2fc58b3c8f2 386 SUPERFAMILY SSF53067 23 56 3.48E-27 T 28-03-2018 A6A12_RS03235 30ed6ea232115b0d6902d2fc58b3c8f2 386 SUPERFAMILY SSF53067 160 360 3.48E-27 T 28-03-2018 A6A12_RS02710 1d4ff1cac8dee1035a1a790345deb3c9 168 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 134 2.4E-37 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A6A12_RS02710 1d4ff1cac8dee1035a1a790345deb3c9 168 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 134 2.3E-46 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A6A12_RS02710 1d4ff1cac8dee1035a1a790345deb3c9 168 Gene3D G3DSA:3.30.70.560 1 156 4.5E-56 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A6A12_RS02710 1d4ff1cac8dee1035a1a790345deb3c9 168 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A6A12_RS02710 1d4ff1cac8dee1035a1a790345deb3c9 168 SUPERFAMILY SSF55083 1 157 3.27E-54 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A6A12_RS06445 94448e8ae132ba6988ac72d87d20c528 222 TIGRFAM TIGR04322 rSAM_QueE_Ecoli: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 8 221 7.9E-109 T 28-03-2018 IPR027609 Putative 7-carboxy-7-deazaguanine synthase QueE, Proteobacteria KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A6A12_RS06445 94448e8ae132ba6988ac72d87d20c528 222 SUPERFAMILY SSF102114 27 124 1.83E-6 T 28-03-2018 A6A12_RS06445 94448e8ae132ba6988ac72d87d20c528 222 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 2 222 34.28 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A6A12_RS06445 94448e8ae132ba6988ac72d87d20c528 222 Pfam PF13394 4Fe-4S single cluster domain 23 127 4.6E-11 T 28-03-2018 A6A12_RS06445 94448e8ae132ba6988ac72d87d20c528 222 PIRSF PIRSF000370 1 222 7.2E-67 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A6A12_RS06445 94448e8ae132ba6988ac72d87d20c528 222 Gene3D G3DSA:3.20.20.70 16 211 3.0E-12 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS04110 4e79585fb9d2fa538fe159d55c18b332 755 Gene3D G3DSA:1.25.40.10 248 297 7.3E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS04110 4e79585fb9d2fa538fe159d55c18b332 755 Gene3D G3DSA:1.25.40.10 298 443 1.9E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS04110 4e79585fb9d2fa538fe159d55c18b332 755 Pfam PF13424 Tetratricopeptide repeat 251 314 7.8E-8 T 28-03-2018 A6A12_RS04110 4e79585fb9d2fa538fe159d55c18b332 755 Gene3D G3DSA:1.25.40.10 31 215 2.8E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS04110 4e79585fb9d2fa538fe159d55c18b332 755 Gene3D G3DSA:3.30.70.270 508 706 6.1E-6 T 28-03-2018 A6A12_RS04110 4e79585fb9d2fa538fe159d55c18b332 755 SMART SM00028 291 324 0.022 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS04110 4e79585fb9d2fa538fe159d55c18b332 755 SMART SM00028 85 118 16.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS04110 4e79585fb9d2fa538fe159d55c18b332 755 SMART SM00028 411 444 110.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS04110 4e79585fb9d2fa538fe159d55c18b332 755 SMART SM00028 251 284 38.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS04110 4e79585fb9d2fa538fe159d55c18b332 755 SUPERFAMILY SSF48452 330 440 6.83E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS04110 4e79585fb9d2fa538fe159d55c18b332 755 SUPERFAMILY SSF48452 175 360 3.03E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS13695 f3c5e4b831d3c4536bd870f25aa53411 930 SUPERFAMILY SSF63411 501 725 8.38E-16 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A6A12_RS13695 f3c5e4b831d3c4536bd870f25aa53411 930 Gene3D G3DSA:3.30.830.10 499 722 3.9E-12 T 28-03-2018 A6A12_RS13695 f3c5e4b831d3c4536bd870f25aa53411 930 SUPERFAMILY SSF63411 32 255 7.52E-40 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A6A12_RS13695 f3c5e4b831d3c4536bd870f25aa53411 930 Pfam PF05193 Peptidase M16 inactive domain 697 856 1.6E-15 T 28-03-2018 IPR007863 Peptidase M16, C-terminal A6A12_RS13695 f3c5e4b831d3c4536bd870f25aa53411 930 Pfam PF05193 Peptidase M16 inactive domain 206 387 4.5E-14 T 28-03-2018 IPR007863 Peptidase M16, C-terminal A6A12_RS13695 f3c5e4b831d3c4536bd870f25aa53411 930 Gene3D G3DSA:3.30.830.10 277 478 1.3E-10 T 28-03-2018 A6A12_RS13695 f3c5e4b831d3c4536bd870f25aa53411 930 Gene3D G3DSA:3.30.830.10 723 929 3.1E-23 T 28-03-2018 A6A12_RS13695 f3c5e4b831d3c4536bd870f25aa53411 930 Gene3D G3DSA:3.30.830.10 20 253 1.6E-46 T 28-03-2018 A6A12_RS13695 f3c5e4b831d3c4536bd870f25aa53411 930 SUPERFAMILY SSF63411 745 924 2.67E-19 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A6A12_RS13695 f3c5e4b831d3c4536bd870f25aa53411 930 SUPERFAMILY SSF63411 305 472 1.28E-5 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A6A12_RS13695 f3c5e4b831d3c4536bd870f25aa53411 930 Pfam PF00675 Insulinase (Peptidase family M16) 47 178 2.4E-20 T 28-03-2018 IPR011765 Peptidase M16, N-terminal A6A12_RS08840 12c6146f5b6dde60ac5f3feb5d94d199 206 SUPERFAMILY SSF46929 160 205 1.57E-11 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 A6A12_RS08840 12c6146f5b6dde60ac5f3feb5d94d199 206 Pfam PF01330 RuvA N terminal domain 2 62 4.7E-20 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 A6A12_RS08840 12c6146f5b6dde60ac5f3feb5d94d199 206 Gene3D G3DSA:2.40.50.140 2 66 1.4E-23 T 28-03-2018 A6A12_RS08840 12c6146f5b6dde60ac5f3feb5d94d199 206 Pfam PF14520 Helix-hairpin-helix domain 72 130 1.6E-13 T 28-03-2018 A6A12_RS08840 12c6146f5b6dde60ac5f3feb5d94d199 206 Pfam PF07499 RuvA, C-terminal domain 162 205 3.3E-15 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 A6A12_RS08840 12c6146f5b6dde60ac5f3feb5d94d199 206 SUPERFAMILY SSF50249 2 63 3.6E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS08840 12c6146f5b6dde60ac5f3feb5d94d199 206 SUPERFAMILY SSF47781 66 136 1.72E-19 T 28-03-2018 IPR010994 RuvA domain 2-like A6A12_RS08840 12c6146f5b6dde60ac5f3feb5d94d199 206 Gene3D G3DSA:1.10.150.20 121 172 0.055 T 28-03-2018 A6A12_RS08840 12c6146f5b6dde60ac5f3feb5d94d199 206 SMART SM00278 108 127 0.071 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A6A12_RS08840 12c6146f5b6dde60ac5f3feb5d94d199 206 SMART SM00278 73 92 540.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A6A12_RS08840 12c6146f5b6dde60ac5f3feb5d94d199 206 Gene3D G3DSA:1.10.8.10 173 205 2.0E-16 T 28-03-2018 A6A12_RS08840 12c6146f5b6dde60ac5f3feb5d94d199 206 Gene3D G3DSA:1.10.150.20 67 120 3.6E-9 T 28-03-2018 A6A12_RS08840 12c6146f5b6dde60ac5f3feb5d94d199 206 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 206 31.421 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A6A12_RS08840 12c6146f5b6dde60ac5f3feb5d94d199 206 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 205 2.3E-63 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 Gene3D G3DSA:3.30.565.10 416 583 6.4E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 SMART SM00387 468 583 1.9E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 Gene3D G3DSA:3.40.50.2300 597 803 1.2E-30 T 28-03-2018 A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 Gene3D G3DSA:3.30.450.20 38 188 7.3E-17 T 28-03-2018 A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 Pfam PF00072 Response regulator receiver domain 605 716 1.1E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 SUPERFAMILY SSF52172 600 732 4.98E-29 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 Gene3D G3DSA:3.30.450.20 189 271 7.5E-4 T 28-03-2018 A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 561 2.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 522 2.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 536 2.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 PRINTS PR00344 Bacterial sensor protein C-terminal signature 567 580 2.7E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 SMART SM00388 356 421 2.3E-24 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 Gene3D G3DSA:1.10.287.130 347 415 3.7E-17 T 28-03-2018 A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 SUPERFAMILY SSF55874 410 580 3.27E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 Pfam PF00512 His Kinase A (phospho-acceptor) domain 356 421 5.3E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 SMART SM00448 602 716 7.1E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 SUPERFAMILY SSF47384 343 422 5.1E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 469 579 5.2E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS08750 d6b7d1f906c235dcd1c05c60e922e0a2 811 Pfam PF02743 Cache domain 44 232 1.4E-12 T 28-03-2018 IPR033479 Double Cache domain 1 A6A12_RS10030 5ca006d824564fd77faeebee544521db 130 ProSitePatterns PS01000 Succinate dehydrogenase cytochrome b subunit signature 1. 11 35 - T 28-03-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS10030 5ca006d824564fd77faeebee544521db 130 PIRSF PIRSF000178 2 130 1.8E-32 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS10030 5ca006d824564fd77faeebee544521db 130 SUPERFAMILY SSF81343 8 130 2.29E-33 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS10030 5ca006d824564fd77faeebee544521db 130 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 9 127 3.8E-40 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS10030 5ca006d824564fd77faeebee544521db 130 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 8 124 1.3E-28 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS10030 5ca006d824564fd77faeebee544521db 130 Gene3D G3DSA:1.20.1300.10 4 130 5.4E-25 T 28-03-2018 A6A12_RS10030 5ca006d824564fd77faeebee544521db 130 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 86 99 - T 28-03-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS01740 391ea6deec1631e709c9daa7c593facd 311 Gene3D G3DSA:3.90.110.10 148 311 4.1E-42 T 28-03-2018 A6A12_RS01740 391ea6deec1631e709c9daa7c593facd 311 PIRSF PIRSF000102 1 306 5.0E-59 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 A6A12_RS01740 391ea6deec1631e709c9daa7c593facd 311 TIGRFAM TIGR01772 MDH_euk_gproteo: malate dehydrogenase, NAD-dependent 2 310 1.4E-126 T 28-03-2018 IPR010097 Malate dehydrogenase, type 1 GO:0006099|GO:0030060 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263|Reactome: R-HSA-71403 A6A12_RS01740 391ea6deec1631e709c9daa7c593facd 311 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 1 145 8.2E-47 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 A6A12_RS01740 391ea6deec1631e709c9daa7c593facd 311 SUPERFAMILY SSF56327 146 310 1.16E-40 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 A6A12_RS01740 391ea6deec1631e709c9daa7c593facd 311 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 147 309 5.4E-46 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 A6A12_RS01740 391ea6deec1631e709c9daa7c593facd 311 Hamap MF_01516 Malate dehydrogenase [mdh]. 1 311 57.299 T 28-03-2018 IPR023958 Malate dehydrogenase, type 1, bacterial GO:0006099|GO:0030060|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 A6A12_RS01740 391ea6deec1631e709c9daa7c593facd 311 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 146 158 - T 28-03-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A6A12_RS01740 391ea6deec1631e709c9daa7c593facd 311 SUPERFAMILY SSF51735 1 145 4.18E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS01740 391ea6deec1631e709c9daa7c593facd 311 Gene3D G3DSA:3.40.50.720 2 147 2.5E-41 T 28-03-2018 A6A12_RS09885 90aa9455920a133fe6ce669e490fa578 329 PIRSF PIRSF020479 6 329 2.5E-118 T 28-03-2018 IPR014506 Uncharacterised conserved protein UCP020479, signal transduction CheW-like A6A12_RS09885 90aa9455920a133fe6ce669e490fa578 329 Gene3D G3DSA:2.40.50.180 205 295 0.006 T 28-03-2018 A6A12_RS09885 90aa9455920a133fe6ce669e490fa578 329 SMART SM00260 181 315 0.0035 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS09885 90aa9455920a133fe6ce669e490fa578 329 SUPERFAMILY SSF50341 183 317 2.22E-13 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS09885 90aa9455920a133fe6ce669e490fa578 329 Pfam PF01584 CheW-like domain 185 317 7.9E-14 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS09560 7807c32b70f3da76f7fb4cb9bd1611fc 435 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 85 424 1.2E-107 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 A6A12_RS09560 7807c32b70f3da76f7fb4cb9bd1611fc 435 Gene3D G3DSA:3.60.120.10 2 427 5.7E-95 T 28-03-2018 IPR005801 ADC synthase GO:0009058 A6A12_RS09560 7807c32b70f3da76f7fb4cb9bd1611fc 435 SUPERFAMILY SSF56322 26 425 3.27E-101 T 28-03-2018 IPR005801 ADC synthase GO:0009058 A6A12_RS09560 7807c32b70f3da76f7fb4cb9bd1611fc 435 Pfam PF00425 chorismate binding enzyme 166 417 1.8E-73 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A6A12_RS09560 7807c32b70f3da76f7fb4cb9bd1611fc 435 Hamap MF_01935 Isochorismate synthase MenF [menF]. 3 427 31.842 T 28-03-2018 IPR034681 Isochorismate synthase MenF GO:0008909|GO:0009234 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 A6A12_RS10810 1ad4d1c99adb8e5b7b815aa24b75be71 284 Hamap MF_01119 UPF0294 protein YafD [yafD]. 5 283 52.906 T 28-03-2018 IPR022958 Uncharacterised protein family UPF0294 A6A12_RS10810 1ad4d1c99adb8e5b7b815aa24b75be71 284 Gene3D G3DSA:3.60.10.10 66 283 2.0E-13 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A6A12_RS10810 1ad4d1c99adb8e5b7b815aa24b75be71 284 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 71 275 6.9E-6 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A6A12_RS10810 1ad4d1c99adb8e5b7b815aa24b75be71 284 SUPERFAMILY SSF56219 65 284 4.06E-23 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A6A12_RS01985 61989aef5c664b592d08e6f56cc5ab53 651 Pfam PF07715 TonB-dependent Receptor Plug Domain 45 155 1.5E-27 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 A6A12_RS01985 61989aef5c664b592d08e6f56cc5ab53 651 Gene3D G3DSA:2.40.170.20 166 651 1.5E-78 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A6A12_RS01985 61989aef5c664b592d08e6f56cc5ab53 651 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 634 651 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site A6A12_RS01985 61989aef5c664b592d08e6f56cc5ab53 651 Gene3D G3DSA:2.170.130.10 22 162 2.9E-35 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 A6A12_RS01985 61989aef5c664b592d08e6f56cc5ab53 651 Pfam PF00593 TonB dependent receptor 179 649 4.1E-56 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A6A12_RS01985 61989aef5c664b592d08e6f56cc5ab53 651 SUPERFAMILY SSF56935 32 651 1.72E-123 T 28-03-2018 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 Gene3D G3DSA:3.20.20.10 15 230 1.3E-47 T 28-03-2018 IPR029066 PLP-binding barrel A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 Gene3D G3DSA:2.40.37.10 231 371 8.9E-57 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 Pfam PF01168 Alanine racemase, N-terminal domain 22 233 3.9E-73 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 PRINTS PR00992 Alanine racemase signature 206 233 3.9E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 PRINTS PR00992 Alanine racemase signature 353 366 3.9E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 PRINTS PR00992 Alanine racemase signature 301 318 3.9E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 PRINTS PR00992 Alanine racemase signature 263 278 3.9E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 PRINTS PR00992 Alanine racemase signature 280 295 3.9E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 PRINTS PR00992 Alanine racemase signature 40 56 3.9E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 PRINTS PR00992 Alanine racemase signature 134 146 3.9E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 PRINTS PR00992 Alanine racemase signature 169 180 3.9E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 PRINTS PR00992 Alanine racemase signature 74 92 3.9E-69 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 Pfam PF00842 Alanine racemase, C-terminal domain 247 370 4.8E-43 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 SUPERFAMILY SSF51419 22 248 1.7E-71 T 28-03-2018 IPR029066 PLP-binding barrel A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 TIGRFAM TIGR00492 alr: alanine racemase 17 370 1.6E-131 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 SMART SM01005 247 371 2.1E-68 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 SUPERFAMILY SSF50621 242 370 4.19E-47 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 45 55 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS01410 9ef9fd968cece70cea6091b154a6f78b 371 Hamap MF_01201 Alanine racemase. 15 371 35.644 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS06830 8b66a30b3636512ca08444b879b7696a 351 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS06830 8b66a30b3636512ca08444b879b7696a 351 Pfam PF00005 ABC transporter 24 164 9.8E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS06830 8b66a30b3636512ca08444b879b7696a 351 Pfam PF08402 TOBE domain 276 341 4.3E-5 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A6A12_RS06830 8b66a30b3636512ca08444b879b7696a 351 Gene3D G3DSA:3.40.50.300 2 245 3.7E-75 T 28-03-2018 A6A12_RS06830 8b66a30b3636512ca08444b879b7696a 351 SUPERFAMILY SSF52540 7 244 3.51E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS06830 8b66a30b3636512ca08444b879b7696a 351 SUPERFAMILY SSF50331 239 347 5.39E-15 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A6A12_RS06830 8b66a30b3636512ca08444b879b7696a 351 SMART SM00382 31 214 1.3E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 SUPERFAMILY SSF55060 206 382 6.72E-53 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 562 571 - T 28-03-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 TIGRFAM TIGR00131 gal_kin: galactokinase 6 381 1.4E-148 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 PRINTS PR00959 Mevalonate kinase family signature 120 142 1.4E-43 T 28-03-2018 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 PRINTS PR00959 Mevalonate kinase family signature 163 182 1.4E-43 T 28-03-2018 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 PRINTS PR00959 Mevalonate kinase family signature 26 50 1.4E-43 T 28-03-2018 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 PRINTS PR00959 Mevalonate kinase family signature 329 346 1.4E-43 T 28-03-2018 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 Pfam PF00288 GHMP kinases N terminal domain 115 182 1.1E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 Pfam PF08544 GHMP kinases C terminal 280 362 2.4E-11 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 Gene3D G3DSA:3.30.70.890 208 382 2.5E-57 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 Pfam PF01263 Aldose 1-epimerase 408 735 5.2E-83 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 SUPERFAMILY SSF74650 393 736 4.65E-101 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 SUPERFAMILY SSF54211 2 204 7.59E-65 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 Gene3D G3DSA:3.30.230.10 3 207 2.5E-57 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 122 133 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 Pfam PF10509 Galactokinase galactose-binding signature 11 59 1.4E-21 T 28-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 Gene3D G3DSA:2.70.98.10 395 738 1.0E-103 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 PRINTS PR00473 Galactokinase signature 28 46 8.5E-29 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 PRINTS PR00473 Galactokinase signature 113 131 8.5E-29 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 PRINTS PR00473 Galactokinase signature 93 104 8.5E-29 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 PRINTS PR00473 Galactokinase signature 264 278 8.5E-29 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 Hamap MF_00246 Galactokinase [galK]. 26 382 43.965 T 28-03-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 TIGRFAM TIGR02636 galM_Leloir: galactose mutarotase 403 736 4.2E-139 T 28-03-2018 IPR013458 Aldose 1-epimerase, bacterial GO:0004034|GO:0006012 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 A6A12_RS11235 25b6ccbd2d98b251aab61159473f37c7 738 ProSitePatterns PS00106 Galactokinase signature. 28 39 - T 28-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A6A12_RS14075 0178b4c1c7b4fb65b6804be11dcb9158 250 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 5 241 17.981 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A6A12_RS14075 0178b4c1c7b4fb65b6804be11dcb9158 250 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 10 227 1.7E-76 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A6A12_RS14075 0178b4c1c7b4fb65b6804be11dcb9158 250 Pfam PF00902 Sec-independent protein translocase protein (TatC) 13 222 6.9E-67 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A6A12_RS14075 0178b4c1c7b4fb65b6804be11dcb9158 250 ProSitePatterns PS01218 TatC family signature. 155 174 - T 28-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site A6A12_RS14075 0178b4c1c7b4fb65b6804be11dcb9158 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 86 104 4.0E-51 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A6A12_RS14075 0178b4c1c7b4fb65b6804be11dcb9158 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 9 36 4.0E-51 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A6A12_RS14075 0178b4c1c7b4fb65b6804be11dcb9158 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 104 130 4.0E-51 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A6A12_RS14075 0178b4c1c7b4fb65b6804be11dcb9158 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 155 183 4.0E-51 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 A6A12_RS10050 84d788ad9d264550c4300bc3405ebc8b 548 Gene3D G3DSA:3.40.120.10 12 213 8.9E-49 T 28-03-2018 A6A12_RS10050 84d788ad9d264550c4300bc3405ebc8b 548 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 40 180 5.8E-39 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS10050 84d788ad9d264550c4300bc3405ebc8b 548 SUPERFAMILY SSF53738 305 447 2.75E-31 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS10050 84d788ad9d264550c4300bc3405ebc8b 548 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 320 438 9.3E-29 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS10050 84d788ad9d264550c4300bc3405ebc8b 548 SUPERFAMILY SSF53738 27 235 9.18E-52 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS10050 84d788ad9d264550c4300bc3405ebc8b 548 Gene3D G3DSA:3.30.310.50 444 546 9.8E-21 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS10050 84d788ad9d264550c4300bc3405ebc8b 548 SUPERFAMILY SSF55957 432 543 2.09E-19 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS10050 84d788ad9d264550c4300bc3405ebc8b 548 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS10050 84d788ad9d264550c4300bc3405ebc8b 548 Gene3D G3DSA:3.40.120.10 332 443 7.6E-27 T 28-03-2018 A6A12_RS10050 84d788ad9d264550c4300bc3405ebc8b 548 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 1 543 0.0 T 28-03-2018 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6317|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 A6A12_RS10050 84d788ad9d264550c4300bc3405ebc8b 548 Gene3D G3DSA:3.40.120.10 214 331 7.5E-22 T 28-03-2018 A6A12_RS10050 84d788ad9d264550c4300bc3405ebc8b 548 SUPERFAMILY SSF53738 209 317 4.36E-8 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS10050 84d788ad9d264550c4300bc3405ebc8b 548 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 317 6.9E-18 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS10050 84d788ad9d264550c4300bc3405ebc8b 548 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 490 535 4.2E-7 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS08180 85052d3673f0e4950a3b902660992122 610 SUPERFAMILY SSF47781 521 609 1.24E-19 T 28-03-2018 IPR010994 RuvA domain 2-like A6A12_RS08180 85052d3673f0e4950a3b902660992122 610 Gene3D G3DSA:1.10.150.20 554 610 7.0E-14 T 28-03-2018 A6A12_RS08180 85052d3673f0e4950a3b902660992122 610 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 607 28.364 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 A6A12_RS08180 85052d3673f0e4950a3b902660992122 610 Pfam PF14520 Helix-hairpin-helix domain 558 609 1.0E-10 T 28-03-2018 A6A12_RS08180 85052d3673f0e4950a3b902660992122 610 SUPERFAMILY SSF46600 190 243 7.59E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 A6A12_RS08180 85052d3673f0e4950a3b902660992122 610 SUPERFAMILY SSF82771 16 100 1.44E-23 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily A6A12_RS08180 85052d3673f0e4950a3b902660992122 610 Gene3D G3DSA:4.10.860.10 182 241 2.7E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 A6A12_RS08180 85052d3673f0e4950a3b902660992122 610 Pfam PF01541 GIY-YIG catalytic domain 18 93 8.6E-13 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily A6A12_RS08180 85052d3673f0e4950a3b902660992122 610 Pfam PF02151 UvrB/uvrC motif 205 238 3.1E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 A6A12_RS08180 85052d3673f0e4950a3b902660992122 610 Gene3D G3DSA:3.40.1440.10 7 101 7.9E-24 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily A6A12_RS08180 85052d3673f0e4950a3b902660992122 610 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 387 542 1.2E-42 T 28-03-2018 IPR001162 UvrC family homology region A6A12_RS08180 85052d3673f0e4950a3b902660992122 610 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 10 589 1.5E-212 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 A6A12_RS08180 85052d3673f0e4950a3b902660992122 610 SMART SM00278 556 575 0.25 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A6A12_RS08180 85052d3673f0e4950a3b902660992122 610 SMART SM00278 588 607 18.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A6A12_RS08180 85052d3673f0e4950a3b902660992122 610 SMART SM00465 17 98 3.0E-22 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 Pfam PF04545 Sigma-70, region 4 552 605 1.8E-19 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 380 605 7.4E-38 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 Pfam PF04542 Sigma-70 region 2 384 453 1.7E-21 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 Gene3D G3DSA:1.10.10.10 454 504 6.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 PRINTS PR00046 Major sigma-70 factor signature 432 440 3.1E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 PRINTS PR00046 Major sigma-70 factor signature 556 568 3.1E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 PRINTS PR00046 Major sigma-70 factor signature 592 603 3.1E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 PRINTS PR00046 Major sigma-70 factor signature 577 592 3.1E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 PRINTS PR00046 Major sigma-70 factor signature 408 421 3.1E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 Pfam PF03979 Sigma-70 factor, region 1.1 4 80 3.4E-28 T 28-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 Pfam PF04546 Sigma-70, non-essential region 139 353 2.4E-65 T 28-03-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 Pfam PF04539 Sigma-70 region 3 463 538 1.3E-28 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 SUPERFAMILY SSF88659 457 530 2.22E-20 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 SUPERFAMILY SSF88659 514 616 8.5E-26 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 SUPERFAMILY SSF88946 115 451 3.79E-96 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 408 421 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 4 617 46.034 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 577 603 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 Gene3D G3DSA:1.10.601.10 115 453 5.0E-104 T 28-03-2018 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 Gene3D G3DSA:1.10.601.10 6 114 3.3E-14 T 28-03-2018 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 380 616 2.0E-120 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 Gene3D G3DSA:1.10.10.10 548 617 1.4E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS02330 06ea79c20f261bdbf0a116b0baf41d9b 618 Pfam PF00140 Sigma-70 factor, region 1.2 98 128 1.8E-12 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS07610 24c7d34716ceccd71dcfc3709a82ee53 504 SMART SM00052 251 496 5.5E-99 T 28-03-2018 IPR001633 EAL domain A6A12_RS07610 24c7d34716ceccd71dcfc3709a82ee53 504 Gene3D G3DSA:3.20.20.450 250 504 3.0E-82 T 28-03-2018 IPR001633 EAL domain A6A12_RS07610 24c7d34716ceccd71dcfc3709a82ee53 504 SUPERFAMILY SSF141868 258 502 4.32E-77 T 28-03-2018 IPR001633 EAL domain A6A12_RS07610 24c7d34716ceccd71dcfc3709a82ee53 504 Pfam PF00563 EAL domain 258 491 4.6E-63 T 28-03-2018 IPR001633 EAL domain A6A12_RS07610 24c7d34716ceccd71dcfc3709a82ee53 504 Pfam PF12792 CSS motif domain associated with EAL 53 223 3.8E-21 T 28-03-2018 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain A6A12_RS14430 1e9403ca95075415ca903e9ddafbf8ed 118 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 56 70 - T 28-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 A6A12_RS14430 1e9403ca95075415ca903e9ddafbf8ed 118 Gene3D G3DSA:3.30.230.10 1 118 1.2E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A6A12_RS14430 1e9403ca95075415ca903e9ddafbf8ed 118 SUPERFAMILY SSF54211 4 114 1.8E-29 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS14430 1e9403ca95075415ca903e9ddafbf8ed 118 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 16 104 4.0E-42 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A6A12_RS14430 1e9403ca95075415ca903e9ddafbf8ed 118 Pfam PF00825 Ribonuclease P 6 112 7.0E-32 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A6A12_RS14430 1e9403ca95075415ca903e9ddafbf8ed 118 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 6 113 2.2E-27 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A6A12_RS14430 1e9403ca95075415ca903e9ddafbf8ed 118 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 6 115 16.971 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 A6A12_RS09055 0ec963ccaa40c20dac9a0cf89a076a92 429 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 333 4.6E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS09055 0ec963ccaa40c20dac9a0cf89a076a92 429 SUPERFAMILY SSF51905 3 103 7.11E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS09055 0ec963ccaa40c20dac9a0cf89a076a92 429 SUPERFAMILY SSF51905 220 347 7.11E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS09055 0ec963ccaa40c20dac9a0cf89a076a92 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 2.0E-13 T 28-03-2018 A6A12_RS09055 0ec963ccaa40c20dac9a0cf89a076a92 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 2.0E-13 T 28-03-2018 A6A12_RS09055 0ec963ccaa40c20dac9a0cf89a076a92 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 2.0E-13 T 28-03-2018 A6A12_RS09055 0ec963ccaa40c20dac9a0cf89a076a92 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.0E-13 T 28-03-2018 A6A12_RS09055 0ec963ccaa40c20dac9a0cf89a076a92 429 Gene3D G3DSA:3.50.50.60 1 139 1.7E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS09055 0ec963ccaa40c20dac9a0cf89a076a92 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 4.2E-7 T 28-03-2018 A6A12_RS09055 0ec963ccaa40c20dac9a0cf89a076a92 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 192 4.2E-7 T 28-03-2018 A6A12_RS09055 0ec963ccaa40c20dac9a0cf89a076a92 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.2E-7 T 28-03-2018 A6A12_RS09055 0ec963ccaa40c20dac9a0cf89a076a92 429 Gene3D G3DSA:3.50.50.60 140 343 3.4E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS05610 8191daf021c5c09f46ed50a80827e919 373 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 11 369 9.1E-152 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 A6A12_RS05610 8191daf021c5c09f46ed50a80827e919 373 Gene3D G3DSA:2.40.30.10 291 373 2.2E-27 T 28-03-2018 A6A12_RS05610 8191daf021c5c09f46ed50a80827e919 373 Gene3D G3DSA:2.30.30.280 220 289 2.6E-24 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 A6A12_RS05610 8191daf021c5c09f46ed50a80827e919 373 Pfam PF03054 tRNA methyl transferase 11 369 1.0E-142 T 28-03-2018 A6A12_RS05610 8191daf021c5c09f46ed50a80827e919 373 SUPERFAMILY SSF52402 9 251 1.52E-58 T 28-03-2018 A6A12_RS05610 8191daf021c5c09f46ed50a80827e919 373 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 11 370 40.192 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 A6A12_RS05610 8191daf021c5c09f46ed50a80827e919 373 Gene3D G3DSA:3.40.50.620 2 219 7.0E-65 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS04510 764924410640ffbd5cd2a64cd9c0912f 92 Gene3D G3DSA:3.40.30.10 1 92 2.9E-37 T 28-03-2018 A6A12_RS04510 764924410640ffbd5cd2a64cd9c0912f 92 Pfam PF10262 Rdx family 9 78 5.2E-30 T 28-03-2018 IPR011893 Selenoprotein, Rdx type A6A12_RS04510 764924410640ffbd5cd2a64cd9c0912f 92 SUPERFAMILY SSF52833 6 87 6.93E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS04510 764924410640ffbd5cd2a64cd9c0912f 92 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 9 77 1.6E-23 T 28-03-2018 IPR011893 Selenoprotein, Rdx type A6A12_RS07990 5e2341879477f020a0b4ccdf63336b00 404 Gene3D G3DSA:1.20.1250.20 5 197 4.6E-33 T 28-03-2018 A6A12_RS07990 5e2341879477f020a0b4ccdf63336b00 404 SUPERFAMILY SSF103473 7 391 3.14E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain A6A12_RS07990 5e2341879477f020a0b4ccdf63336b00 404 Gene3D G3DSA:1.20.1250.20 201 402 6.9E-14 T 28-03-2018 A6A12_RS07990 5e2341879477f020a0b4ccdf63336b00 404 Pfam PF07690 Major Facilitator Superfamily 16 352 1.9E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A6A12_RS02575 e84f24862a06fe42eb4161c4300ae339 117 PIRSF PIRSF002191 1 117 1.8E-51 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02575 e84f24862a06fe42eb4161c4300ae339 117 PRINTS PR00061 Ribosomal protein L19 signature 88 113 1.3E-40 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02575 e84f24862a06fe42eb4161c4300ae339 117 PRINTS PR00061 Ribosomal protein L19 signature 34 63 1.3E-40 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02575 e84f24862a06fe42eb4161c4300ae339 117 PRINTS PR00061 Ribosomal protein L19 signature 4 33 1.3E-40 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02575 e84f24862a06fe42eb4161c4300ae339 117 SUPERFAMILY SSF50104 2 115 1.6E-47 T 28-03-2018 IPR008991 Translation protein SH3-like domain A6A12_RS02575 e84f24862a06fe42eb4161c4300ae339 117 Pfam PF01245 Ribosomal protein L19 3 113 5.4E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02575 e84f24862a06fe42eb4161c4300ae339 117 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 7.6E-52 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02575 e84f24862a06fe42eb4161c4300ae339 117 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 31.325 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02575 e84f24862a06fe42eb4161c4300ae339 117 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS07910 3a20691a766ddf585a2bada82e0da0c3 259 SUPERFAMILY SSF53850 29 258 3.37E-32 T 28-03-2018 A6A12_RS07910 3a20691a766ddf585a2bada82e0da0c3 259 Gene3D G3DSA:3.40.190.10 27 176 2.5E-16 T 28-03-2018 A6A12_RS07910 3a20691a766ddf585a2bada82e0da0c3 259 SMART SM00062 31 257 0.002 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS07910 3a20691a766ddf585a2bada82e0da0c3 259 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 241 1.7E-20 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS07910 3a20691a766ddf585a2bada82e0da0c3 259 Gene3D G3DSA:3.40.190.10 177 259 0.0077 T 28-03-2018 A6A12_RS06615 afb0acd4112fce162d7b8739227b94ce 1613 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 76 1602 0.0 T 28-03-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 A6A12_RS06615 afb0acd4112fce162d7b8739227b94ce 1613 Gene3D G3DSA:3.40.50.720 938 1263 9.8E-44 T 28-03-2018 A6A12_RS06615 afb0acd4112fce162d7b8739227b94ce 1613 SUPERFAMILY SSF51735 945 1047 1.05E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS06615 afb0acd4112fce162d7b8739227b94ce 1613 SUPERFAMILY SSF51735 1083 1253 1.05E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS06615 afb0acd4112fce162d7b8739227b94ce 1613 SUPERFAMILY SSF53223 755 940 3.64E-24 T 28-03-2018 A6A12_RS06615 afb0acd4112fce162d7b8739227b94ce 1613 PIRSF PIRSF036761 1 1610 0.0 T 28-03-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 A6A12_RS06615 afb0acd4112fce162d7b8739227b94ce 1613 Gene3D G3DSA:3.40.50.10860 794 932 1.2E-4 T 28-03-2018 A6A12_RS03440 8e148d1116c016e4c099a433c08d61e6 300 Pfam PF03466 LysR substrate binding domain 93 296 1.4E-35 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS03440 8e148d1116c016e4c099a433c08d61e6 300 SUPERFAMILY SSF46785 4 116 6.33E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03440 8e148d1116c016e4c099a433c08d61e6 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 67 3.3E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS03440 8e148d1116c016e4c099a433c08d61e6 300 Gene3D G3DSA:3.40.190.10 93 182 9.1E-14 T 28-03-2018 A6A12_RS03440 8e148d1116c016e4c099a433c08d61e6 300 Gene3D G3DSA:3.40.190.10 183 274 1.9E-12 T 28-03-2018 A6A12_RS03440 8e148d1116c016e4c099a433c08d61e6 300 SUPERFAMILY SSF53850 93 298 9.46E-32 T 28-03-2018 A6A12_RS03440 8e148d1116c016e4c099a433c08d61e6 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 7.2E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS03440 8e148d1116c016e4c099a433c08d61e6 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 7.2E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS03440 8e148d1116c016e4c099a433c08d61e6 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 7.2E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS03440 8e148d1116c016e4c099a433c08d61e6 300 Gene3D G3DSA:1.10.10.10 2 86 6.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 Pfam PF13365 Trypsin-like peptidase domain 92 228 4.6E-30 T 28-03-2018 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 Gene3D G3DSA:2.40.10.10 140 257 1.1E-42 T 28-03-2018 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 SUPERFAMILY SSF50494 37 263 1.24E-63 T 28-03-2018 IPR009003 Peptidase S1, PA clan A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 39 452 7.6E-163 T 28-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 Gene3D G3DSA:2.30.42.10 262 365 1.1E-29 T 28-03-2018 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 373 443 9.7E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 Gene3D G3DSA:2.30.42.10 366 454 1.5E-14 T 28-03-2018 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 Pfam PF13180 PDZ domain 268 358 1.5E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 PRINTS PR00834 HtrA/DegQ protease family signature 199 216 8.4E-58 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 PRINTS PR00834 HtrA/DegQ protease family signature 102 114 8.4E-58 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 PRINTS PR00834 HtrA/DegQ protease family signature 164 188 8.4E-58 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 PRINTS PR00834 HtrA/DegQ protease family signature 123 143 8.4E-58 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 PRINTS PR00834 HtrA/DegQ protease family signature 307 319 8.4E-58 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 PRINTS PR00834 HtrA/DegQ protease family signature 221 238 8.4E-58 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 SMART SM00228 370 446 7.3E-7 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 SMART SM00228 267 349 5.9E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 Gene3D G3DSA:2.40.10.10 30 139 2.5E-30 T 28-03-2018 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 SUPERFAMILY SSF50156 225 350 2.76E-26 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS11650 eb8ad4c79d6e2cc16f942ff96664228a 454 SUPERFAMILY SSF50156 384 451 3.81E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 SUPERFAMILY SSF55874 198 347 4.98E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 SMART SM00387 233 348 5.4E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 SUPERFAMILY SSF55785 7 101 1.58E-10 T 28-03-2018 IPR000014 PAS domain A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 SMART SM00388 129 194 6.9E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 Gene3D G3DSA:3.30.450.20 1 124 9.6E-16 T 28-03-2018 A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 Pfam PF00989 PAS fold 7 111 3.5E-17 T 28-03-2018 IPR013767 PAS fold GO:0006355 A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 329 1.2E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 347 1.2E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 PRINTS PR00344 Bacterial sensor protein C-terminal signature 282 296 1.2E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 SMART SM00091 4 72 1.7E-7 T 28-03-2018 IPR000014 PAS domain A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 Pfam PF00512 His Kinase A (phospho-acceptor) domain 133 189 5.4E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 Gene3D G3DSA:1.10.287.130 125 189 1.1E-13 T 28-03-2018 A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 8 121 2.5E-7 T 28-03-2018 IPR000014 PAS domain A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 SUPERFAMILY SSF47384 125 189 2.94E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 Gene3D G3DSA:3.30.565.10 192 348 7.5E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS00800 0d2c517a6a3964f0011aaaa10c15b071 348 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 234 347 1.7E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS00830 add77cb8be681551ad9696d09b752b5b 310 SUPERFAMILY SSF55729 2 157 1.17E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS00830 add77cb8be681551ad9696d09b752b5b 310 Gene3D G3DSA:3.40.630.30 1 145 3.6E-22 T 28-03-2018 A6A12_RS00830 add77cb8be681551ad9696d09b752b5b 310 TIGRFAM TIGR02447 yiiD_Cterm: putative thioesterase domain 164 296 3.8E-45 T 28-03-2018 IPR012660 Thioesterase, putative A6A12_RS00830 add77cb8be681551ad9696d09b752b5b 310 Gene3D G3DSA:3.10.129.10 151 300 3.8E-21 T 28-03-2018 A6A12_RS00830 add77cb8be681551ad9696d09b752b5b 310 Pfam PF00583 Acetyltransferase (GNAT) family 20 122 9.0E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A6A12_RS00830 add77cb8be681551ad9696d09b752b5b 310 SUPERFAMILY SSF54637 154 296 1.9E-41 T 28-03-2018 IPR029069 HotDog domain A6A12_RS00830 add77cb8be681551ad9696d09b752b5b 310 Pfam PF09500 Putative thioesterase (yiiD_Cterm) 157 296 5.1E-51 T 28-03-2018 IPR012660 Thioesterase, putative A6A12_RS03945 fcedd05359c5a3c2cadb5965415dcfde 377 SUPERFAMILY SSF51735 166 339 9.49E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS03945 fcedd05359c5a3c2cadb5965415dcfde 377 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 67 81 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A6A12_RS03945 fcedd05359c5a3c2cadb5965415dcfde 377 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 34 160 1.3E-25 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A6A12_RS03945 fcedd05359c5a3c2cadb5965415dcfde 377 Gene3D G3DSA:3.90.180.10 2 193 3.6E-59 T 28-03-2018 A6A12_RS03945 fcedd05359c5a3c2cadb5965415dcfde 377 Gene3D G3DSA:3.40.50.720 194 316 2.9E-25 T 28-03-2018 A6A12_RS03945 fcedd05359c5a3c2cadb5965415dcfde 377 Pfam PF00107 Zinc-binding dehydrogenase 203 324 3.1E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A6A12_RS03945 fcedd05359c5a3c2cadb5965415dcfde 377 SUPERFAMILY SSF50129 4 193 3.1E-72 T 28-03-2018 IPR011032 GroES-like A6A12_RS03945 fcedd05359c5a3c2cadb5965415dcfde 377 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 8 375 4.9E-224 T 28-03-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 A6A12_RS03945 fcedd05359c5a3c2cadb5965415dcfde 377 SUPERFAMILY SSF50129 324 375 1.6E-11 T 28-03-2018 IPR011032 GroES-like A6A12_RS03945 fcedd05359c5a3c2cadb5965415dcfde 377 SMART SM00829 16 373 0.0011 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A6A12_RS00225 c20c9c4d98daa22a78c0db99789b4c3d 88 Pfam PF06288 Protein of unknown function (DUF1040) 1 86 5.3E-46 T 28-03-2018 IPR009383 Protein of unknown function DUF1040 A6A12_RS00225 c20c9c4d98daa22a78c0db99789b4c3d 88 ProDom PD029038 YIHD CYTOPLASMIC ENZYME Y3814 GLYCOGEN YPO0013A HI0845 DIRECT ORF1 UNCHARACTERIZED 1 87 8.0E-36 T 28-03-2018 IPR009383 Protein of unknown function DUF1040 A6A12_RS12470 77fd8592ce8d3655f7ee03a68b11bbcc 136 SUPERFAMILY SSF54686 3 133 4.71E-53 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A6A12_RS12470 77fd8592ce8d3655f7ee03a68b11bbcc 136 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 125 3.5E-57 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12470 77fd8592ce8d3655f7ee03a68b11bbcc 136 Pfam PF00252 Ribosomal protein L16p/L10e 4 131 1.2E-46 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A6A12_RS12470 77fd8592ce8d3655f7ee03a68b11bbcc 136 Gene3D G3DSA:3.90.1170.10 1 136 1.7E-49 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A6A12_RS12470 77fd8592ce8d3655f7ee03a68b11bbcc 136 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 58 69 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12470 77fd8592ce8d3655f7ee03a68b11bbcc 136 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 133 37.42 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12470 77fd8592ce8d3655f7ee03a68b11bbcc 136 PRINTS PR00060 Ribosomal protein L16 signature 87 116 6.6E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12470 77fd8592ce8d3655f7ee03a68b11bbcc 136 PRINTS PR00060 Ribosomal protein L16 signature 41 52 6.6E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12470 77fd8592ce8d3655f7ee03a68b11bbcc 136 PRINTS PR00060 Ribosomal protein L16 signature 23 35 6.6E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12470 77fd8592ce8d3655f7ee03a68b11bbcc 136 PRINTS PR00060 Ribosomal protein L16 signature 57 86 6.6E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS10005 a8c0965716880efdbddadd4e1119050e 402 Gene3D G3DSA:3.90.1170.30 54 93 0.36 T 28-03-2018 A6A12_RS10005 a8c0965716880efdbddadd4e1119050e 402 Gene3D G3DSA:3.90.1170.30 7 53 1.6E-13 T 28-03-2018 A6A12_RS10005 a8c0965716880efdbddadd4e1119050e 402 Pfam PF00364 Biotin-requiring enzyme 4 76 1.5E-18 T 28-03-2018 IPR000089 Biotin/lipoyl attachment A6A12_RS10005 a8c0965716880efdbddadd4e1119050e 402 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 402 3.2E-185 T 28-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A6A12_RS10005 a8c0965716880efdbddadd4e1119050e 402 SUPERFAMILY SSF47005 106 149 1.7E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A6A12_RS10005 a8c0965716880efdbddadd4e1119050e 402 Pfam PF02817 e3 binding domain 113 145 6.9E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A6A12_RS10005 a8c0965716880efdbddadd4e1119050e 402 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A6A12_RS10005 a8c0965716880efdbddadd4e1119050e 402 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 172 400 2.9E-81 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A6A12_RS10005 a8c0965716880efdbddadd4e1119050e 402 SUPERFAMILY SSF52777 172 401 7.56E-90 T 28-03-2018 A6A12_RS10005 a8c0965716880efdbddadd4e1119050e 402 SUPERFAMILY SSF51230 1 95 1.83E-24 T 28-03-2018 IPR011053 Single hybrid motif A6A12_RS10005 a8c0965716880efdbddadd4e1119050e 402 Gene3D G3DSA:3.30.559.10 161 400 1.2E-92 T 28-03-2018 A6A12_RS10005 a8c0965716880efdbddadd4e1119050e 402 Gene3D G3DSA:4.10.320.10 94 160 1.2E-18 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 SUPERFAMILY SSF50800 74 169 3.49E-24 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 PRINTS PR01050 Pyruvate kinase family signature 275 299 5.5E-54 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 PRINTS PR01050 Pyruvate kinase family signature 190 204 5.5E-54 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 PRINTS PR01050 Pyruvate kinase family signature 63 79 5.5E-54 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 PRINTS PR01050 Pyruvate kinase family signature 223 249 5.5E-54 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 PRINTS PR01050 Pyruvate kinase family signature 300 318 5.5E-54 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 PRINTS PR01050 Pyruvate kinase family signature 250 274 5.5E-54 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 PRINTS PR01050 Pyruvate kinase family signature 319 335 5.5E-54 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 Gene3D G3DSA:3.40.1380.20 328 481 9.1E-44 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 Gene3D G3DSA:3.20.20.60 6 173 2.8E-35 T 28-03-2018 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 Gene3D G3DSA:3.20.20.60 174 327 1.9E-54 T 28-03-2018 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 Pfam PF00224 Pyruvate kinase, barrel domain 6 349 1.3E-128 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 479 4.1E-166 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 ProSitePatterns PS00110 Pyruvate kinase active site signature. 218 230 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 SUPERFAMILY SSF52935 329 480 1.44E-37 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 Pfam PF02887 Pyruvate kinase, alpha/beta domain 363 478 5.6E-29 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 SUPERFAMILY SSF51621 5 79 9.03E-86 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A6A12_RS09615 4be13e9645fc9dd3042b8187f5a3f266 482 SUPERFAMILY SSF51621 171 346 9.03E-86 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A6A12_RS07825 db0899c38dd2d5b0e9ad7ccd4e149589 169 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 8 161 2.8E-57 T 28-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 A6A12_RS07825 db0899c38dd2d5b0e9ad7ccd4e149589 169 PIRSF PIRSF028301 1 169 1.2E-57 T 28-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 A6A12_RS07825 db0899c38dd2d5b0e9ad7ccd4e149589 169 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 6 162 4.4E-55 T 28-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 A6A12_RS09000 003993f9c3f64e2454f5412697d8e5e7 335 SUPERFAMILY SSF52540 50 170 2.54E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09000 003993f9c3f64e2454f5412697d8e5e7 335 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 1 328 40.957 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 A6A12_RS09000 003993f9c3f64e2454f5412697d8e5e7 335 Gene3D G3DSA:3.40.50.720 277 322 0.18 T 28-03-2018 A6A12_RS09000 003993f9c3f64e2454f5412697d8e5e7 335 Gene3D G3DSA:3.40.50.300 34 276 4.6E-6 T 28-03-2018 A6A12_RS09000 003993f9c3f64e2454f5412697d8e5e7 335 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 18 322 4.6E-111 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 A6A12_RS09000 003993f9c3f64e2454f5412697d8e5e7 335 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 23 325 1.8E-95 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 SUPERFAMILY SSF47384 363 439 2.16E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 SUPERFAMILY SSF55874 442 592 4.06E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 Pfam PF02743 Cache domain 39 214 4.6E-15 T 28-03-2018 IPR033479 Double Cache domain 1 A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 Gene3D G3DSA:3.30.565.10 437 593 1.2E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 SMART SM00387 484 592 2.5E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 551 1.2E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 576 589 1.2E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 570 1.2E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 523 537 1.2E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 PIRSF PIRSF036431 1 595 1.0E-186 T 28-03-2018 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 Gene3D G3DSA:3.30.450.20 164 289 6.8E-7 T 28-03-2018 A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 Gene3D G3DSA:1.10.287.130 344 436 2.7E-11 T 28-03-2018 A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 Gene3D G3DSA:3.30.450.20 54 163 2.4E-23 T 28-03-2018 A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 SMART SM00388 373 441 9.1E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 Pfam PF00512 His Kinase A (phospho-acceptor) domain 374 439 3.1E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 SUPERFAMILY SSF103190 48 187 8.24E-30 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A6A12_RS05175 dc46a8ac94b96ee546c28f23525e0098 595 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 486 589 4.4E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS03275 8e7a6f8c0bc19e3d0625a675362e0225 657 Gene3D G3DSA:1.10.1240.20 421 485 1.1E-14 T 28-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 A6A12_RS03275 8e7a6f8c0bc19e3d0625a675362e0225 657 Gene3D G3DSA:1.10.530.10 486 657 1.6E-36 T 28-03-2018 A6A12_RS03275 8e7a6f8c0bc19e3d0625a675362e0225 657 Gene3D G3DSA:1.25.20.10 41 403 8.8E-48 T 28-03-2018 A6A12_RS03275 8e7a6f8c0bc19e3d0625a675362e0225 657 SUPERFAMILY SSF48435 42 490 1.83E-119 T 28-03-2018 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 A6A12_RS03275 8e7a6f8c0bc19e3d0625a675362e0225 657 SUPERFAMILY SSF53955 493 649 6.29E-46 T 28-03-2018 IPR023346 Lysozyme-like domain A6A12_RS03275 8e7a6f8c0bc19e3d0625a675362e0225 657 Pfam PF14718 Soluble lytic murein transglycosylase L domain 420 485 1.7E-22 T 28-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 A6A12_RS03275 8e7a6f8c0bc19e3d0625a675362e0225 657 Pfam PF01464 Transglycosylase SLT domain 498 610 7.4E-29 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 287 8.1E-146 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 PIRSF PIRSF001553 1 289 2.7E-134 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 Gene3D G3DSA:3.40.50.261 120 289 3.2E-56 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 SMART SM00881 4 100 1.6E-35 T 28-03-2018 IPR003781 CoA-binding GO:0048037 A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 SUPERFAMILY SSF51735 1 122 1.04E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 Gene3D G3DSA:3.40.50.720 1 119 7.2E-45 T 28-03-2018 A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 Pfam PF00549 CoA-ligase 151 271 1.2E-21 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 43.263 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.8E-40 T 28-03-2018 A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.8E-40 T 28-03-2018 A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.8E-40 T 28-03-2018 A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.8E-40 T 28-03-2018 A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 Pfam PF02629 CoA binding domain 6 99 6.5E-31 T 28-03-2018 IPR003781 CoA-binding GO:0048037 A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site A6A12_RS09995 563fdbf6d05ac3e7990288c874be5901 290 SUPERFAMILY SSF52210 123 286 2.09E-56 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A6A12_RS05020 c13443950ff4300872f2a11036b181de 284 PRINTS PR00412 Epoxide hydrolase signature 114 127 3.0E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A6A12_RS05020 c13443950ff4300872f2a11036b181de 284 PRINTS PR00412 Epoxide hydrolase signature 54 69 3.0E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A6A12_RS05020 c13443950ff4300872f2a11036b181de 284 PRINTS PR00412 Epoxide hydrolase signature 32 50 3.0E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A6A12_RS05020 c13443950ff4300872f2a11036b181de 284 PRINTS PR00412 Epoxide hydrolase signature 100 113 3.0E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A6A12_RS05020 c13443950ff4300872f2a11036b181de 284 PRINTS PR00412 Epoxide hydrolase signature 258 280 3.0E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A6A12_RS05020 c13443950ff4300872f2a11036b181de 284 Pfam PF12697 Alpha/beta hydrolase family 28 275 4.2E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A6A12_RS05020 c13443950ff4300872f2a11036b181de 284 SUPERFAMILY SSF53474 11 282 4.47E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS05020 c13443950ff4300872f2a11036b181de 284 Gene3D G3DSA:3.40.50.1820 2 279 4.2E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS03080 c7f44b89859dd8b010a95d7d0ed722c8 444 SUPERFAMILY SSF52540 146 372 8.75E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03080 c7f44b89859dd8b010a95d7d0ed722c8 444 SUPERFAMILY SSF46689 352 438 8.74E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS03080 c7f44b89859dd8b010a95d7d0ed722c8 444 Gene3D G3DSA:1.10.8.60 312 378 3.3E-21 T 28-03-2018 A6A12_RS03080 c7f44b89859dd8b010a95d7d0ed722c8 444 Gene3D G3DSA:1.10.10.60 379 443 2.6E-11 T 28-03-2018 A6A12_RS03080 c7f44b89859dd8b010a95d7d0ed722c8 444 Gene3D G3DSA:3.40.50.300 142 311 2.4E-20 T 28-03-2018 A6A12_RS03080 c7f44b89859dd8b010a95d7d0ed722c8 444 SUPERFAMILY SSF52172 27 190 7.9E-8 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS03080 c7f44b89859dd8b010a95d7d0ed722c8 444 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 402 419 5.1E-5 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS03080 c7f44b89859dd8b010a95d7d0ed722c8 444 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 419 439 5.1E-5 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS03080 c7f44b89859dd8b010a95d7d0ed722c8 444 Pfam PF02954 Bacterial regulatory protein, Fis family 396 435 5.3E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS03080 c7f44b89859dd8b010a95d7d0ed722c8 444 Pfam PF00158 Sigma-54 interaction domain 146 305 1.1E-39 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A6A12_RS03080 c7f44b89859dd8b010a95d7d0ed722c8 444 SMART SM00382 166 303 1.2E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS03080 c7f44b89859dd8b010a95d7d0ed722c8 444 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 352 361 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A6A12_RS04945 f42f49f5a101a90be5c08ff4bbb5ff7d 273 Gene3D G3DSA:3.40.50.150 1 273 4.5E-48 T 28-03-2018 A6A12_RS04945 f42f49f5a101a90be5c08ff4bbb5ff7d 273 PIRSF PIRSF018249 1 272 2.3E-83 T 28-03-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 A6A12_RS04945 f42f49f5a101a90be5c08ff4bbb5ff7d 273 SUPERFAMILY SSF53335 5 256 6.84E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS04945 f42f49f5a101a90be5c08ff4bbb5ff7d 273 Pfam PF13847 Methyltransferase domain 84 224 1.1E-10 T 28-03-2018 IPR025714 Methyltransferase domain A6A12_RS07600 9c55ae16b08c2e5478b58f51efc499ae 479 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A6A12_RS07600 9c55ae16b08c2e5478b58f51efc499ae 479 Pfam PF02378 Phosphotransferase system, EIIC 110 410 6.2E-50 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A6A12_RS07600 9c55ae16b08c2e5478b58f51efc499ae 479 Pfam PF00367 phosphotransferase system, EIIB 8 41 1.0E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A6A12_RS07600 9c55ae16b08c2e5478b58f51efc499ae 479 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 2 464 1.1E-196 T 28-03-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 A6A12_RS07600 9c55ae16b08c2e5478b58f51efc499ae 479 SUPERFAMILY SSF55604 6 82 5.36E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A6A12_RS07600 9c55ae16b08c2e5478b58f51efc499ae 479 Gene3D G3DSA:3.30.1360.60 5 81 1.2E-26 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A6A12_RS07600 9c55ae16b08c2e5478b58f51efc499ae 479 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 28 110 1.2E-22 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A6A12_RS07600 9c55ae16b08c2e5478b58f51efc499ae 479 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 164 453 2.6E-94 T 28-03-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 A6A12_RS04585 086f14fd71fac1948a883bfe6fe9e014 264 PIRSF PIRSF001430 1 257 1.9E-75 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS04585 086f14fd71fac1948a883bfe6fe9e014 264 SUPERFAMILY SSF55120 1 255 6.47E-94 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS04585 086f14fd71fac1948a883bfe6fe9e014 264 Gene3D G3DSA:3.30.70.580 1 104 1.2E-34 T 28-03-2018 A6A12_RS04585 086f14fd71fac1948a883bfe6fe9e014 264 Gene3D G3DSA:3.30.70.660 105 242 4.2E-37 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS04585 086f14fd71fac1948a883bfe6fe9e014 264 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 243 34.58 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS04585 086f14fd71fac1948a883bfe6fe9e014 264 Pfam PF01416 tRNA pseudouridine synthase 144 244 1.6E-27 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS04585 086f14fd71fac1948a883bfe6fe9e014 264 Pfam PF01416 tRNA pseudouridine synthase 8 102 8.2E-8 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS04585 086f14fd71fac1948a883bfe6fe9e014 264 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 238 3.4E-76 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS11800 4d9633d1ebbbf2c1e566342947d25e25 225 Pfam PF00035 Double-stranded RNA binding motif 155 222 4.7E-15 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain A6A12_RS11800 4d9633d1ebbbf2c1e566342947d25e25 225 Gene3D G3DSA:1.10.1520.10 1 150 2.7E-44 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A6A12_RS11800 4d9633d1ebbbf2c1e566342947d25e25 225 SMART SM00535 20 148 1.3E-54 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A6A12_RS11800 4d9633d1ebbbf2c1e566342947d25e25 225 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 8 222 1.9E-73 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A6A12_RS11800 4d9633d1ebbbf2c1e566342947d25e25 225 SMART SM00358 155 223 6.0E-20 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain A6A12_RS11800 4d9633d1ebbbf2c1e566342947d25e25 225 ProSitePatterns PS00517 Ribonuclease III family signature. 37 45 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A6A12_RS11800 4d9633d1ebbbf2c1e566342947d25e25 225 Pfam PF14622 Ribonuclease-III-like 18 141 2.9E-33 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A6A12_RS11800 4d9633d1ebbbf2c1e566342947d25e25 225 SUPERFAMILY SSF69065 5 158 4.01E-50 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 A6A12_RS11800 4d9633d1ebbbf2c1e566342947d25e25 225 Gene3D G3DSA:3.30.160.20 154 225 1.8E-20 T 28-03-2018 A6A12_RS11800 4d9633d1ebbbf2c1e566342947d25e25 225 SUPERFAMILY SSF54768 108 222 1.41E-27 T 28-03-2018 A6A12_RS11800 4d9633d1ebbbf2c1e566342947d25e25 225 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 219 29.687 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 A6A12_RS12120 d93afc8bf37050b799a1a71851bda765 263 Pfam PF02405 Permease MlaE 48 259 5.9E-75 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 A6A12_RS12120 d93afc8bf37050b799a1a71851bda765 263 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 9 261 8.0E-99 T 28-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria A6A12_RS10515 ef023d3f6987121252ded648d1d9eaf2 293 Gene3D G3DSA:1.10.8.10 4 84 6.3E-22 T 28-03-2018 A6A12_RS10515 ef023d3f6987121252ded648d1d9eaf2 293 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 186 192 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A6A12_RS10515 ef023d3f6987121252ded648d1d9eaf2 293 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 8 282 1.3E-81 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 A6A12_RS10515 ef023d3f6987121252ded648d1d9eaf2 293 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 6 281 44.915 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A6A12_RS10515 ef023d3f6987121252ded648d1d9eaf2 293 Pfam PF13847 Methyltransferase domain 117 246 2.4E-19 T 28-03-2018 IPR025714 Methyltransferase domain A6A12_RS10515 ef023d3f6987121252ded648d1d9eaf2 293 SUPERFAMILY SSF53335 6 281 6.98E-61 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS10515 ef023d3f6987121252ded648d1d9eaf2 293 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 28 277 9.3E-92 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A6A12_RS10515 ef023d3f6987121252ded648d1d9eaf2 293 Gene3D G3DSA:3.40.50.150 85 284 5.6E-43 T 28-03-2018 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 Gene3D G3DSA:2.60.40.10 621 726 2.9E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 SMART SM01038 753 1027 2.9E-91 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 Gene3D G3DSA:2.70.98.10 733 1029 6.2E-79 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 Gene3D G3DSA:2.60.120.260 1 215 7.6E-66 T 28-03-2018 IPR008979 Galactose-binding domain-like A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 Pfam PF00703 Glycosyl hydrolases family 2 219 329 3.1E-14 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 SUPERFAMILY SSF49785 9 215 2.55E-65 T 28-03-2018 IPR008979 Galactose-binding domain-like A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 443 457 - T 28-03-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 331 623 6.0E-113 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 SUPERFAMILY SSF49303 617 726 5.28E-25 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 PRINTS PR00132 Glycosyl hydrolase family 2 signature 371 389 3.2E-38 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 PRINTS PR00132 Glycosyl hydrolase family 2 signature 340 354 3.2E-38 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 PRINTS PR00132 Glycosyl hydrolase family 2 signature 443 458 3.2E-38 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 PRINTS PR00132 Glycosyl hydrolase family 2 signature 527 542 3.2E-38 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 PRINTS PR00132 Glycosyl hydrolase family 2 signature 143 158 3.2E-38 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 Pfam PF16353 Domain of unknown function(DUF4981) 638 723 8.2E-20 T 28-03-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 48 215 1.5E-55 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 Gene3D G3DSA:2.60.40.10 217 329 5.1E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 Pfam PF02929 Beta galactosidase small chain 757 1025 5.8E-62 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 SUPERFAMILY SSF49303 219 329 4.6E-22 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 Gene3D G3DSA:3.20.20.80 330 620 1.7E-86 T 28-03-2018 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 SUPERFAMILY SSF74650 743 1026 7.06E-86 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 Hamap MF_01687 Beta-galactosidase [lacZ]. 2 1029 16.718 T 28-03-2018 IPR023933 Glycoside hydrolase, family 2, beta-galactosidase GO:0016798 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A6A12_RS00625 00543a6add3bb234a1c3021246c55d10 1033 SUPERFAMILY SSF51445 330 618 6.03E-100 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A6A12_RS12885 4f2a5fc08dd561ecfe5337bee28d11ba 443 Gene3D G3DSA:3.40.50.300 7 124 1.8E-5 T 28-03-2018 A6A12_RS12885 4f2a5fc08dd561ecfe5337bee28d11ba 443 SMART SM01086 335 429 1.3E-19 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A6A12_RS12885 4f2a5fc08dd561ecfe5337bee28d11ba 443 Pfam PF07724 AAA domain (Cdc48 subfamily) 174 329 4.1E-42 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A6A12_RS12885 4f2a5fc08dd561ecfe5337bee28d11ba 443 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 103 8.2E-7 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A6A12_RS12885 4f2a5fc08dd561ecfe5337bee28d11ba 443 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 443 42.95 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 A6A12_RS12885 4f2a5fc08dd561ecfe5337bee28d11ba 443 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 335 404 8.7E-5 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A6A12_RS12885 4f2a5fc08dd561ecfe5337bee28d11ba 443 SUPERFAMILY SSF52540 3 441 3.56E-95 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12885 4f2a5fc08dd561ecfe5337bee28d11ba 443 Gene3D G3DSA:1.10.8.60 335 431 6.6E-29 T 28-03-2018 A6A12_RS12885 4f2a5fc08dd561ecfe5337bee28d11ba 443 Gene3D G3DSA:1.10.8.10 201 243 1.3E-14 T 28-03-2018 A6A12_RS12885 4f2a5fc08dd561ecfe5337bee28d11ba 443 Gene3D G3DSA:1.10.8.10 125 200 3.1E-30 T 28-03-2018 A6A12_RS12885 4f2a5fc08dd561ecfe5337bee28d11ba 443 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 4 443 1.9E-219 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 A6A12_RS12885 4f2a5fc08dd561ecfe5337bee28d11ba 443 SMART SM00382 49 332 1.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS03885 1a4264c7e96e3bcc45a225ce1847662b 472 TIGRFAM TIGR02617 tnaA_trp_ase: tryptophanase 5 471 5.0E-292 T 28-03-2018 IPR013440 Tryptophanase GO:0006568|GO:0009034 KEGG: 00380+4.1.99.1 A6A12_RS03885 1a4264c7e96e3bcc45a225ce1847662b 472 SUPERFAMILY SSF53383 6 471 8.28E-122 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS03885 1a4264c7e96e3bcc45a225ce1847662b 472 Hamap MF_00544 Tryptophanase [tnaA]. 4 471 96.479 T 28-03-2018 IPR013440 Tryptophanase GO:0006568|GO:0009034 KEGG: 00380+4.1.99.1 A6A12_RS03885 1a4264c7e96e3bcc45a225ce1847662b 472 Pfam PF01212 Beta-eliminating lyase 49 437 1.2E-87 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 A6A12_RS03885 1a4264c7e96e3bcc45a225ce1847662b 472 PIRSF PIRSF001386 3 472 1.9E-204 T 28-03-2018 IPR011166 Beta-eliminating lyase family GO:0009072|GO:0016830 KEGG: 00380+4.1.99.1 A6A12_RS03885 1a4264c7e96e3bcc45a225ce1847662b 472 Gene3D G3DSA:3.90.1150.10 20 112 1.4E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS03885 1a4264c7e96e3bcc45a225ce1847662b 472 Gene3D G3DSA:3.90.1150.10 289 469 1.5E-68 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS03885 1a4264c7e96e3bcc45a225ce1847662b 472 ProSitePatterns PS00853 Beta-eliminating lyases pyridoxal-phosphate attachment site. 260 278 - T 28-03-2018 IPR018176 Tryptophanase, conserved site KEGG: 00380+4.1.99.1 A6A12_RS01970 2df5c0faec341244c83e79f97f2fce1a 384 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 259 267 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A6A12_RS01970 2df5c0faec341244c83e79f97f2fce1a 384 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 381 58.553 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A6A12_RS01970 2df5c0faec341244c83e79f97f2fce1a 384 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 233 369 1.5E-69 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A6A12_RS01970 2df5c0faec341244c83e79f97f2fce1a 384 Gene3D G3DSA:3.30.300.10 11 133 3.1E-44 T 28-03-2018 A6A12_RS01970 2df5c0faec341244c83e79f97f2fce1a 384 Gene3D G3DSA:3.30.300.10 246 383 1.5E-48 T 28-03-2018 A6A12_RS01970 2df5c0faec341244c83e79f97f2fce1a 384 PIRSF PIRSF000497 1 381 3.5E-174 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A6A12_RS01970 2df5c0faec341244c83e79f97f2fce1a 384 SUPERFAMILY SSF55973 233 382 6.67E-71 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A6A12_RS01970 2df5c0faec341244c83e79f97f2fce1a 384 SUPERFAMILY SSF55973 3 109 1.77E-46 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A6A12_RS01970 2df5c0faec341244c83e79f97f2fce1a 384 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 116 126 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A6A12_RS01970 2df5c0faec341244c83e79f97f2fce1a 384 Gene3D G3DSA:3.30.300.10 134 233 3.3E-42 T 28-03-2018 A6A12_RS01970 2df5c0faec341244c83e79f97f2fce1a 384 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 379 2.1E-196 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A6A12_RS01970 2df5c0faec341244c83e79f97f2fce1a 384 Pfam PF02772 S-adenosylmethionine synthetase, central domain 114 231 3.4E-45 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A6A12_RS01970 2df5c0faec341244c83e79f97f2fce1a 384 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 1.5E-42 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A6A12_RS01970 2df5c0faec341244c83e79f97f2fce1a 384 SUPERFAMILY SSF55973 111 232 2.24E-51 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 PRINTS PR00458 Haem peroxidase superfamily signature 150 167 1.4E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 PRINTS PR00458 Haem peroxidase superfamily signature 168 180 1.4E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 PRINTS PR00458 Haem peroxidase superfamily signature 90 104 1.4E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 PRINTS PR00458 Haem peroxidase superfamily signature 318 333 1.4E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 PRINTS PR00458 Haem peroxidase superfamily signature 259 274 1.4E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 Gene3D G3DSA:1.10.420.10 232 399 1.5E-43 T 28-03-2018 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 Gene3D G3DSA:1.10.420.10 593 699 1.2E-34 T 28-03-2018 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 Gene3D G3DSA:1.10.520.10 56 213 3.0E-38 T 28-03-2018 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 Pfam PF00141 Peroxidase 69 397 3.1E-51 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 Pfam PF00141 Peroxidase 406 698 3.0E-34 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 SUPERFAMILY SSF48113 432 722 1.62E-112 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 ProSitePatterns PS00436 Peroxidases active site signature. 90 101 - T 28-03-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 11 723 0.0 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 Hamap MF_01961 Catalase-peroxidase [katG]. 7 724 40.359 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 Gene3D G3DSA:1.10.520.10 444 592 1.1E-36 T 28-03-2018 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 SUPERFAMILY SSF48113 19 431 1.25E-153 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 67 92 7.9E-52 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 267 290 7.9E-52 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 52 65 7.9E-52 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 478 504 7.9E-52 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 A6A12_RS03640 440fb1c1f789f3bb3c2f563e58b4fa8f 724 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 26 48 7.9E-52 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 A6A12_RS08230 60ec6ff46a9cafcd1f10937c534d69da 565 PIRSF PIRSF001423 1 563 4.5E-294 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A6A12_RS08230 60ec6ff46a9cafcd1f10937c534d69da 565 Pfam PF17391 Urocanase N-terminal domain 17 143 4.1E-62 T 28-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A6A12_RS08230 60ec6ff46a9cafcd1f10937c534d69da 565 Hamap MF_00577 Urocanate hydratase [hutU]. 4 558 49.236 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A6A12_RS08230 60ec6ff46a9cafcd1f10937c534d69da 565 Pfam PF01175 Urocanase Rossmann-like domain 146 351 3.9E-84 T 28-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A6A12_RS08230 60ec6ff46a9cafcd1f10937c534d69da 565 SUPERFAMILY SSF111326 11 558 2.35E-258 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A6A12_RS08230 60ec6ff46a9cafcd1f10937c534d69da 565 Pfam PF17392 Urocanase C-terminal domain 354 548 6.8E-92 T 28-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A6A12_RS08230 60ec6ff46a9cafcd1f10937c534d69da 565 Gene3D G3DSA:3.40.1770.10 201 557 1.8E-161 T 28-03-2018 A6A12_RS08230 60ec6ff46a9cafcd1f10937c534d69da 565 Gene3D G3DSA:3.40.1770.10 15 158 2.6E-29 T 28-03-2018 A6A12_RS08230 60ec6ff46a9cafcd1f10937c534d69da 565 TIGRFAM TIGR01228 hutU: urocanate hydratase 15 556 3.0E-291 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A6A12_RS08230 60ec6ff46a9cafcd1f10937c534d69da 565 ProSitePatterns PS01233 Urocanase signature. 444 459 - T 28-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A6A12_RS00530 5cab40586e8d88045b0fd4b050f3db80 88 Pfam PF06611 Protein of unknown function (DUF1145) 4 59 1.1E-17 T 28-03-2018 IPR009525 Protein of unknown function DUF1145 A6A12_RS05265 c5602bf0d080236394df16670db1550c 374 SUPERFAMILY SSF52283 305 360 3.66E-67 T 28-03-2018 A6A12_RS05265 c5602bf0d080236394df16670db1550c 374 SUPERFAMILY SSF52283 1 137 3.66E-67 T 28-03-2018 A6A12_RS05265 c5602bf0d080236394df16670db1550c 374 Gene3D G3DSA:3.50.50.60 178 197 5.2E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS05265 c5602bf0d080236394df16670db1550c 374 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 8.9E-152 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 A6A12_RS05265 c5602bf0d080236394df16670db1550c 374 SUPERFAMILY SSF51735 137 303 5.25E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS05265 c5602bf0d080236394df16670db1550c 374 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 1.0E-81 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A6A12_RS05265 c5602bf0d080236394df16670db1550c 374 Gene3D G3DSA:3.40.50.720 198 371 5.1E-45 T 28-03-2018 A6A12_RS05265 c5602bf0d080236394df16670db1550c 374 Gene3D G3DSA:3.40.50.720 1 177 1.5E-44 T 28-03-2018 A6A12_RS05265 c5602bf0d080236394df16670db1550c 374 SMART SM01003 4 137 7.9E-78 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A6A12_RS05265 c5602bf0d080236394df16670db1550c 374 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 8.2E-46 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal A6A12_RS05265 c5602bf0d080236394df16670db1550c 374 SMART SM01002 149 297 1.1E-84 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain A6A12_RS05265 c5602bf0d080236394df16670db1550c 374 PIRSF PIRSF000183 1 371 2.9E-155 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 A6A12_RS07125 5ee23e9d701eed3817fc145e2ca6de96 626 SUPERFAMILY SSF54631 155 275 1.52E-29 T 28-03-2018 A6A12_RS07125 5ee23e9d701eed3817fc145e2ca6de96 626 Pfam PF03445 Putative nucleotidyltransferase DUF294 305 438 1.1E-45 T 28-03-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 A6A12_RS07125 5ee23e9d701eed3817fc145e2ca6de96 626 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 475 619 1.3E-40 T 28-03-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding A6A12_RS07125 5ee23e9d701eed3817fc145e2ca6de96 626 Pfam PF00571 CBS domain 224 275 1.0E-6 T 28-03-2018 IPR000644 CBS domain A6A12_RS07125 5ee23e9d701eed3817fc145e2ca6de96 626 Pfam PF00571 CBS domain 160 211 8.8E-10 T 28-03-2018 IPR000644 CBS domain A6A12_RS07125 5ee23e9d701eed3817fc145e2ca6de96 626 Pfam PF00027 Cyclic nucleotide-binding domain 59 127 5.4E-9 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A6A12_RS07125 5ee23e9d701eed3817fc145e2ca6de96 626 SUPERFAMILY SSF51206 16 135 2.62E-16 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like A6A12_RS07125 5ee23e9d701eed3817fc145e2ca6de96 626 SMART SM00116 167 214 1.9E-7 T 28-03-2018 IPR000644 CBS domain A6A12_RS07125 5ee23e9d701eed3817fc145e2ca6de96 626 SMART SM00116 231 278 9.1E-4 T 28-03-2018 IPR000644 CBS domain A6A12_RS07125 5ee23e9d701eed3817fc145e2ca6de96 626 Gene3D G3DSA:2.60.120.10 9 148 7.3E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS07125 5ee23e9d701eed3817fc145e2ca6de96 626 Gene3D G3DSA:3.10.580.10 150 389 2.0E-27 T 28-03-2018 A6A12_RS10185 9f584e58941f52482ad7c82ab6f6fd49 350 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 250 319 5.9E-17 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) A6A12_RS10185 9f584e58941f52482ad7c82ab6f6fd49 350 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 3 319 1.2E-121 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A6A12_RS10185 9f584e58941f52482ad7c82ab6f6fd49 350 PRINTS PR00955 Flagellar motor switch protein FliM signature 113 132 1.2E-18 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A6A12_RS10185 9f584e58941f52482ad7c82ab6f6fd49 350 PRINTS PR00955 Flagellar motor switch protein FliM signature 211 229 1.2E-18 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A6A12_RS10185 9f584e58941f52482ad7c82ab6f6fd49 350 PRINTS PR00955 Flagellar motor switch protein FliM signature 88 104 1.2E-18 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A6A12_RS10185 9f584e58941f52482ad7c82ab6f6fd49 350 PRINTS PR00955 Flagellar motor switch protein FliM signature 2 15 1.2E-18 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A6A12_RS10185 9f584e58941f52482ad7c82ab6f6fd49 350 Gene3D G3DSA:2.30.330.10 237 328 1.4E-16 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) A6A12_RS10185 9f584e58941f52482ad7c82ab6f6fd49 350 PIRSF PIRSF002888 1 328 4.5E-92 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A6A12_RS10185 9f584e58941f52482ad7c82ab6f6fd49 350 SUPERFAMILY SSF103039 54 230 1.74E-22 T 28-03-2018 IPR028976 CheC-like domain A6A12_RS10185 9f584e58941f52482ad7c82ab6f6fd49 350 SUPERFAMILY SSF103039 4 13 1.74E-22 T 28-03-2018 IPR028976 CheC-like domain A6A12_RS10185 9f584e58941f52482ad7c82ab6f6fd49 350 SUPERFAMILY SSF101801 247 323 1.23E-13 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) A6A12_RS10185 9f584e58941f52482ad7c82ab6f6fd49 350 Pfam PF02154 Flagellar motor switch protein FliM 37 229 1.3E-82 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 A6A12_RS10185 9f584e58941f52482ad7c82ab6f6fd49 350 Gene3D G3DSA:3.40.1550.10 45 234 8.4E-44 T 28-03-2018 IPR028976 CheC-like domain A6A12_RS05090 6de240b366284276e7eb65ed6c2ff451 137 Pfam PF09905 DNA-binding protein VF530 13 74 3.1E-31 T 28-03-2018 IPR018668 DNA-binding protein VF530-like GO:0003677 A6A12_RS05090 6de240b366284276e7eb65ed6c2ff451 137 Gene3D G3DSA:1.10.720.30 20 76 2.3E-26 T 28-03-2018 IPR003034 SAP domain A6A12_RS09395 39beab6607df244406724c8f4f32ba37 233 SUPERFAMILY SSF52172 1 118 2.7E-37 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS09395 39beab6607df244406724c8f4f32ba37 233 SMART SM00862 146 221 1.1E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS09395 39beab6607df244406724c8f4f32ba37 233 SUPERFAMILY SSF46894 125 222 1.5E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS09395 39beab6607df244406724c8f4f32ba37 233 Gene3D G3DSA:1.10.10.10 119 228 2.4E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09395 39beab6607df244406724c8f4f32ba37 233 SMART SM00448 1 112 1.3E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS09395 39beab6607df244406724c8f4f32ba37 233 Pfam PF00072 Response regulator receiver domain 3 112 1.8E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS09395 39beab6607df244406724c8f4f32ba37 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 2.5E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS09395 39beab6607df244406724c8f4f32ba37 233 Gene3D G3DSA:3.40.50.2300 1 118 2.9E-32 T 28-03-2018 A6A12_RS01660 0790a9896e025890bc36a0fedc526e70 295 Pfam PF04085 rod shape-determining protein MreC 123 269 4.0E-41 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 A6A12_RS01660 0790a9896e025890bc36a0fedc526e70 295 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 1 274 8.7E-87 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 A6A12_RS01660 0790a9896e025890bc36a0fedc526e70 295 PIRSF PIRSF038471 2 283 8.9E-83 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 A6A12_RS12100 1b820ad842e5a395912f1d025234d6da 84 Pfam PF01722 BolA-like protein 20 74 6.0E-14 T 28-03-2018 IPR002634 BolA protein A6A12_RS12100 1b820ad842e5a395912f1d025234d6da 84 Gene3D G3DSA:3.30.300.90 1 83 2.4E-24 T 28-03-2018 A6A12_RS12100 1b820ad842e5a395912f1d025234d6da 84 PIRSF PIRSF003113 2 83 1.5E-22 T 28-03-2018 IPR002634 BolA protein A6A12_RS12100 1b820ad842e5a395912f1d025234d6da 84 SUPERFAMILY SSF82657 4 82 4.97E-28 T 28-03-2018 IPR002634 BolA protein A6A12_RS10330 38dbae2cd62046d54119474fb424ddef 292 Gene3D G3DSA:3.20.20.70 1 290 3.6E-89 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS10330 38dbae2cd62046d54119474fb424ddef 292 PIRSF PIRSF001365 1 290 8.3E-91 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A6A12_RS10330 38dbae2cd62046d54119474fb424ddef 292 SUPERFAMILY SSF51569 2 288 3.14E-97 T 28-03-2018 A6A12_RS10330 38dbae2cd62046d54119474fb424ddef 292 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A6A12_RS10330 38dbae2cd62046d54119474fb424ddef 292 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 288 64.828 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A6A12_RS10330 38dbae2cd62046d54119474fb424ddef 292 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 287 4.3E-118 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A6A12_RS10330 38dbae2cd62046d54119474fb424ddef 292 Pfam PF00701 Dihydrodipicolinate synthetase family 2 288 7.5E-110 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A6A12_RS10330 38dbae2cd62046d54119474fb424ddef 292 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 A6A12_RS10330 38dbae2cd62046d54119474fb424ddef 292 SMART SM01130 1 290 7.8E-138 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A6A12_RS10330 38dbae2cd62046d54119474fb424ddef 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 1.9E-34 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A6A12_RS10330 38dbae2cd62046d54119474fb424ddef 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 1.9E-34 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A6A12_RS10330 38dbae2cd62046d54119474fb424ddef 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 1.9E-34 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A6A12_RS10330 38dbae2cd62046d54119474fb424ddef 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 1.9E-34 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 A6A12_RS03230 767dcde2cfb825c5b94fa8534076cc43 309 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 9 302 43.896 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 A6A12_RS03230 767dcde2cfb825c5b94fa8534076cc43 309 Gene3D G3DSA:3.40.50.10490 17 246 3.5E-54 T 28-03-2018 A6A12_RS03230 767dcde2cfb825c5b94fa8534076cc43 309 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 192 209 - T 28-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 A6A12_RS03230 767dcde2cfb825c5b94fa8534076cc43 309 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 13 303 7.2E-133 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 A6A12_RS03230 767dcde2cfb825c5b94fa8534076cc43 309 Gene3D G3DSA:1.10.8.10 275 303 3.8E-5 T 28-03-2018 A6A12_RS03230 767dcde2cfb825c5b94fa8534076cc43 309 Gene3D G3DSA:1.10.8.10 247 274 2.2E-11 T 28-03-2018 A6A12_RS03230 767dcde2cfb825c5b94fa8534076cc43 309 Pfam PF01380 SIS domain 137 217 2.1E-10 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A6A12_RS03230 767dcde2cfb825c5b94fa8534076cc43 309 SUPERFAMILY SSF53697 12 256 2.02E-73 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 353 367 8.1E-25 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 682 701 8.1E-25 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 501 515 8.1E-25 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 630 640 8.1E-25 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 705 717 8.1E-25 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 Pfam PF00403 Heavy-metal-associated domain 93 154 1.1E-9 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 Pfam PF00702 haloacid dehalogenase-like hydrolase 497 695 2.2E-29 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 PRINTS PR00943 Copper-transporting ATPase signature 276 295 1.2E-7 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 PRINTS PR00943 Copper-transporting ATPase signature 660 677 1.2E-7 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 PRINTS PR00943 Copper-transporting ATPase signature 296 314 1.2E-7 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 PRINTS PR00943 Copper-transporting ATPase signature 135 155 1.2E-7 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 Gene3D G3DSA:3.30.70.100 87 161 7.5E-16 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 SUPERFAMILY SSF81653 318 402 1.83E-22 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 SUPERFAMILY SSF81665 727 764 4.58E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 SUPERFAMILY SSF81665 250 306 4.58E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 SUPERFAMILY SSF81665 404 495 4.58E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 Gene3D G3DSA:3.40.1110.10 515 641 1.4E-26 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 503 509 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 Pfam PF00122 E1-E2 ATPase 318 478 3.8E-44 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 272 786 1.2E-121 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 245 784 5.1E-161 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 Gene3D G3DSA:1.20.1110.10 245 514 7.7E-35 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 Gene3D G3DSA:1.20.1110.10 642 785 3.5E-21 T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 SUPERFAMILY SSF55008 85 161 2.09E-18 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 ProSitePatterns PS01229 Hypothetical cof family signature 2. 682 704 - T 28-03-2018 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 279 762 8.4E-73 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 4 86 4.4E-26 T 28-03-2018 IPR021993 Putative metal-binding domain of cation transport ATPase A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 SUPERFAMILY SSF56784 500 519 1.4E-48 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 SUPERFAMILY SSF56784 554 782 1.4E-48 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS06720 157005ed6293b5e4e0bce394ca282d9a 790 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 228 784 3.4E-154 T 28-03-2018 A6A12_RS08280 511a7bc377f1ebc7a2a9481cceeabc03 400 Pfam PF12241 Trans-2-enoyl-CoA reductase catalytic region 82 317 6.6E-111 T 28-03-2018 IPR024910 Trans-2-enoyl-CoA reductase catalytic domain, putative KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A6A12_RS08280 511a7bc377f1ebc7a2a9481cceeabc03 400 Pfam PF07055 Enoyl reductase FAD binding domain 326 389 7.1E-32 T 28-03-2018 IPR024906 Enoyl reductase FAD binding domain KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A6A12_RS08280 511a7bc377f1ebc7a2a9481cceeabc03 400 Pfam PF12242 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2 79 3.1E-37 T 28-03-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A6A12_RS08280 511a7bc377f1ebc7a2a9481cceeabc03 400 Hamap MF_01838 Trans-2-enoyl-CoA reductase [NADH] [fabV]. 1 395 57.157 T 28-03-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A6A12_RS10310 0640a731f45d92e4591687bc1641e0a3 377 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 7 375 3.2E-185 T 28-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 A6A12_RS10310 0640a731f45d92e4591687bc1641e0a3 377 SUPERFAMILY SSF53187 6 180 3.14E-65 T 28-03-2018 A6A12_RS10310 0640a731f45d92e4591687bc1641e0a3 377 SUPERFAMILY SSF53187 294 375 3.14E-65 T 28-03-2018 A6A12_RS10310 0640a731f45d92e4591687bc1641e0a3 377 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 4 377 52.576 T 28-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 A6A12_RS10310 0640a731f45d92e4591687bc1641e0a3 377 Pfam PF01546 Peptidase family M20/M25/M40 64 374 1.1E-45 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A6A12_RS10310 0640a731f45d92e4591687bc1641e0a3 377 Gene3D G3DSA:3.40.630.10 289 375 1.9E-5 T 28-03-2018 A6A12_RS10310 0640a731f45d92e4591687bc1641e0a3 377 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 99 137 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A6A12_RS10310 0640a731f45d92e4591687bc1641e0a3 377 Pfam PF07687 Peptidase dimerisation domain 177 284 6.0E-23 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A6A12_RS10310 0640a731f45d92e4591687bc1641e0a3 377 SUPERFAMILY SSF55031 181 290 1.02E-28 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A6A12_RS10310 0640a731f45d92e4591687bc1641e0a3 377 Gene3D G3DSA:3.40.630.10 2 282 9.0E-61 T 28-03-2018 A6A12_RS11525 d0d849adffb9384052074035fe2f874c 353 Gene3D G3DSA:3.40.50.2000 2 170 1.3E-45 T 28-03-2018 A6A12_RS11525 d0d849adffb9384052074035fe2f874c 353 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 3 348 3.2E-122 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A6A12_RS11525 d0d849adffb9384052074035fe2f874c 353 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 7 352 34.864 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A6A12_RS11525 d0d849adffb9384052074035fe2f874c 353 Gene3D G3DSA:3.40.50.2000 171 346 2.4E-31 T 28-03-2018 A6A12_RS11525 d0d849adffb9384052074035fe2f874c 353 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 8 144 3.0E-48 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A6A12_RS11525 d0d849adffb9384052074035fe2f874c 353 SUPERFAMILY SSF53756 5 351 3.33E-126 T 28-03-2018 A6A12_RS11525 d0d849adffb9384052074035fe2f874c 353 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 184 336 1.3E-34 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A6A12_RS08810 49ee78a571fcc046c52bb83b09e5edae 139 SUPERFAMILY SSF54637 7 130 1.12E-39 T 28-03-2018 IPR029069 HotDog domain A6A12_RS08810 49ee78a571fcc046c52bb83b09e5edae 139 Pfam PF03061 Thioesterase superfamily 22 107 4.1E-17 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A6A12_RS08810 49ee78a571fcc046c52bb83b09e5edae 139 Gene3D G3DSA:3.10.129.10 1 137 7.0E-37 T 28-03-2018 A6A12_RS08810 49ee78a571fcc046c52bb83b09e5edae 139 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 8 131 4.7E-51 T 28-03-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 A6A12_RS08810 49ee78a571fcc046c52bb83b09e5edae 139 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 12 127 1.3E-36 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A6A12_RS08810 49ee78a571fcc046c52bb83b09e5edae 139 PIRSF PIRSF003230 1 138 1.4E-47 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 A6A12_RS12585 58c37619f3284094e662c732e6ce03fc 289 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 214 7.7E-70 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 A6A12_RS12585 58c37619f3284094e662c732e6ce03fc 289 PRINTS PR00478 Phosphoribulokinase family signature 126 144 4.1E-27 T 28-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 A6A12_RS12585 58c37619f3284094e662c732e6ce03fc 289 PRINTS PR00478 Phosphoribulokinase family signature 12 29 4.1E-27 T 28-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 A6A12_RS12585 58c37619f3284094e662c732e6ce03fc 289 PRINTS PR00478 Phosphoribulokinase family signature 182 205 4.1E-27 T 28-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 A6A12_RS12585 58c37619f3284094e662c732e6ce03fc 289 PRINTS PR00478 Phosphoribulokinase family signature 164 181 4.1E-27 T 28-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 A6A12_RS12585 58c37619f3284094e662c732e6ce03fc 289 SUPERFAMILY SSF52540 4 286 1.7E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12585 58c37619f3284094e662c732e6ce03fc 289 Gene3D G3DSA:3.40.50.300 1 289 2.3E-43 T 28-03-2018 A6A12_RS11225 1cb0610c8147c48ec5cdc2b0121019f2 184 Gene3D G3DSA:3.10.490.10 1 159 6.4E-19 T 28-03-2018 A6A12_RS11225 1cb0610c8147c48ec5cdc2b0121019f2 184 SUPERFAMILY SSF110857 1 124 2.75E-17 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like A6A12_RS11225 1cb0610c8147c48ec5cdc2b0121019f2 184 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 4 109 9.5E-9 T 28-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 SMART SM00073 6 103 5.6E-20 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 SUPERFAMILY SSF55874 437 620 1.7E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 Gene3D G3DSA:3.30.565.10 437 621 3.9E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 Gene3D G3DSA:1.20.120.160 5 141 6.8E-30 T 28-03-2018 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 Pfam PF01627 Hpt domain 8 101 1.2E-17 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 375 434 3.4E-11 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 PRINTS PR00344 Bacterial sensor protein C-terminal signature 524 538 2.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 PRINTS PR00344 Bacterial sensor protein C-terminal signature 582 600 2.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 PRINTS PR00344 Bacterial sensor protein C-terminal signature 606 619 2.2E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 SMART SM01231 374 434 4.1E-16 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 SUPERFAMILY SSF47384 375 435 2.31E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 Gene3D G3DSA:2.30.30.40 703 755 5.0E-21 T 28-03-2018 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 Gene3D G3DSA:2.30.30.40 622 656 0.015 T 28-03-2018 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 Pfam PF01584 CheW-like domain 628 757 2.7E-21 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 SMART SM00260 614 755 9.1E-33 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 482 621 9.3E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 SMART SM00387 479 622 3.6E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 SUPERFAMILY SSF50341 621 755 2.22E-28 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 Gene3D G3DSA:2.40.50.180 657 702 2.5E-7 T 28-03-2018 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 Gene3D G3DSA:1.10.287.560 374 435 3.9E-15 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A6A12_RS09900 3d491013f9358e02b71ed3abf3c093f8 764 SUPERFAMILY SSF47226 6 127 4.32E-31 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS12975 0ba599e95a6beef53e677f64ff5242e6 158 Gene3D G3DSA:3.40.1280.10 1 158 4.0E-38 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A6A12_RS12975 0ba599e95a6beef53e677f64ff5242e6 158 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 1 157 1.3E-57 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 A6A12_RS12975 0ba599e95a6beef53e677f64ff5242e6 158 PIRSF PIRSF029256 1 158 2.5E-66 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 A6A12_RS12975 0ba599e95a6beef53e677f64ff5242e6 158 Pfam PF00588 SpoU rRNA Methylase family 3 145 3.5E-34 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A6A12_RS12975 0ba599e95a6beef53e677f64ff5242e6 158 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 155 32.525 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 A6A12_RS12975 0ba599e95a6beef53e677f64ff5242e6 158 SUPERFAMILY SSF75217 2 156 6.47E-43 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 Pfam PF00072 Response regulator receiver domain 1029 1140 7.3E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 Gene3D G3DSA:3.30.450.20 625 792 7.4E-22 T 28-03-2018 A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 SUPERFAMILY SSF55874 843 1002 1.15E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 898 1002 1.4E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 Pfam PF12860 PAS fold 634 748 1.6E-43 T 28-03-2018 A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 SMART SM00387 897 1006 4.8E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 Gene3D G3DSA:3.30.565.10 848 1005 1.5E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 SUPERFAMILY SSF52172 1025 1143 5.98E-19 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 Gene3D G3DSA:1.10.287.130 793 847 2.1E-10 T 28-03-2018 A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 SUPERFAMILY SSF55785 626 741 2.3E-8 T 28-03-2018 IPR000014 PAS domain A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 Pfam PF00512 His Kinase A (phospho-acceptor) domain 788 853 9.9E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 SMART SM00448 1027 1140 7.5E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 SUPERFAMILY SSF47384 773 854 1.31E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 SMART SM00388 788 853 1.4E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 PRINTS PR00344 Bacterial sensor protein C-terminal signature 966 984 7.1E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 PRINTS PR00344 Bacterial sensor protein C-terminal signature 933 947 7.1E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 PRINTS PR00344 Bacterial sensor protein C-terminal signature 951 961 7.1E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 PRINTS PR00344 Bacterial sensor protein C-terminal signature 990 1003 7.1E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS13065 7d4cf6863956a0486e3d09ce43a5b6ae 1144 Gene3D G3DSA:3.40.50.2300 1017 1144 4.9E-17 T 28-03-2018 A6A12_RS09160 14c48b7db4e58485ec4d7af5eaca9c60 318 Gene3D G3DSA:3.20.20.70 1 242 2.7E-45 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS09160 14c48b7db4e58485ec4d7af5eaca9c60 318 Pfam PF01207 Dihydrouridine synthase (Dus) 5 296 3.8E-79 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A6A12_RS09160 14c48b7db4e58485ec4d7af5eaca9c60 318 PIRSF PIRSF006621 1 317 1.0E-74 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A6A12_RS09160 14c48b7db4e58485ec4d7af5eaca9c60 318 Hamap MF_02043 tRNA-dihydrouridine(16) synthase [dusC]. 8 310 53.297 T 28-03-2018 IPR032886 tRNA-dihydrouridine(16) synthase GO:0002943|GO:0017150 A6A12_RS09160 14c48b7db4e58485ec4d7af5eaca9c60 318 SUPERFAMILY SSF51395 1 313 5.86E-74 T 28-03-2018 A6A12_RS09160 14c48b7db4e58485ec4d7af5eaca9c60 318 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 92 110 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 A6A12_RS13525 c95287de4b57999e2004963b2274af0c 413 Gene3D G3DSA:3.40.50.10300 196 413 1.3E-68 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A6A12_RS13525 c95287de4b57999e2004963b2274af0c 413 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 13 409 1.2E-148 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 A6A12_RS13525 c95287de4b57999e2004963b2274af0c 413 SUPERFAMILY SSF102645 199 412 1.22E-79 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A6A12_RS13525 c95287de4b57999e2004963b2274af0c 413 Pfam PF02441 Flavoprotein 16 186 4.6E-43 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A6A12_RS13525 c95287de4b57999e2004963b2274af0c 413 SUPERFAMILY SSF52507 10 186 5.1E-59 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A6A12_RS13525 c95287de4b57999e2004963b2274af0c 413 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 200 384 6.0E-75 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A6A12_RS13525 c95287de4b57999e2004963b2274af0c 413 Gene3D G3DSA:3.40.50.1950 8 195 2.1E-53 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A6A12_RS00905 66bd7920e2e5c31e5408426a27b3eba0 165 PIRSF PIRSF006291 2 163 2.6E-36 T 28-03-2018 IPR007690 Type II secretion system, protein M GO:0009306 A6A12_RS00905 66bd7920e2e5c31e5408426a27b3eba0 165 Gene3D G3DSA:3.30.1360.100 87 161 7.1E-25 T 28-03-2018 IPR023229 Type II secretion system protein M, periplasmic domain A6A12_RS00905 66bd7920e2e5c31e5408426a27b3eba0 165 SUPERFAMILY SSF103054 85 163 8.37E-23 T 28-03-2018 IPR023229 Type II secretion system protein M, periplasmic domain A6A12_RS00905 66bd7920e2e5c31e5408426a27b3eba0 165 Pfam PF04612 Type II secretion system (T2SS), protein M 7 162 6.2E-48 T 28-03-2018 IPR007690 Type II secretion system, protein M GO:0009306 A6A12_RS01720 a2a4c3bdb73502b6c9b96edc33777a8c 857 Pfam PF11874 Domain of unknown function (DUF3394) 672 851 2.2E-70 T 28-03-2018 IPR021814 Protein of unknown function DUF3394 A6A12_RS01720 a2a4c3bdb73502b6c9b96edc33777a8c 857 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 32 722 4.8E-212 T 28-03-2018 IPR011853 TRAP transporter, 4TM/12TM fusion protein A6A12_RS01720 a2a4c3bdb73502b6c9b96edc33777a8c 857 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 135 668 1.8E-77 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 PRINTS PR00906 SecA protein signature 101 115 3.1E-72 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 PRINTS PR00906 SecA protein signature 117 127 3.1E-72 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 PRINTS PR00906 SecA protein signature 170 190 3.1E-72 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 PRINTS PR00906 SecA protein signature 340 362 3.1E-72 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 PRINTS PR00906 SecA protein signature 377 394 3.1E-72 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 PRINTS PR00906 SecA protein signature 63 87 3.1E-72 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 PRINTS PR00906 SecA protein signature 414 427 3.1E-72 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 ProSitePatterns PS01312 SecA family signature. 501 516 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 SUPERFAMILY SSF81886 884 896 4.45E-84 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 SUPERFAMILY SSF81886 620 840 4.45E-84 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 SUPERFAMILY SSF81767 227 369 1.83E-42 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 Pfam PF07516 SecA Wing and Scaffold domain 617 829 1.8E-67 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 Pfam PF01043 SecA preprotein cross-linking domain 232 359 1.2E-37 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 832 19.949 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 SUPERFAMILY SSF52540 418 610 1.31E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 SMART SM00957 6 403 0.0 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 Gene3D G3DSA:3.40.50.300 418 633 4.3E-52 T 28-03-2018 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 Pfam PF07517 SecA DEAD-like domain 7 403 1.4E-132 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 SMART SM00958 228 359 3.3E-80 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 817 0.0 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 Pfam PF02810 SEC-C motif 888 906 2.0E-10 T 28-03-2018 IPR004027 SEC-C motif A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 Gene3D G3DSA:3.40.50.300 301 417 1.1E-8 T 28-03-2018 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 Gene3D G3DSA:3.40.50.300 9 267 2.6E-56 T 28-03-2018 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 Gene3D G3DSA:3.10.450.50 734 908 1.1E-53 T 28-03-2018 A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 SUPERFAMILY SSF52540 369 416 7.09E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 SUPERFAMILY SSF52540 5 228 7.09E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11490 71cc3a9d4f11121159335ccb325ccc98 908 Gene3D G3DSA:1.10.3060.10 634 733 9.0E-31 T 28-03-2018 A6A12_RS03545 71dd42868625d47060f64f6b9dbae86c 373 Gene3D G3DSA:3.20.20.70 16 348 3.7E-42 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS03545 71dd42868625d47060f64f6b9dbae86c 373 Pfam PF04055 Radical SAM superfamily 109 280 1.2E-14 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A6A12_RS03545 71dd42868625d47060f64f6b9dbae86c 373 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 5 353 71.719 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS03545 71dd42868625d47060f64f6b9dbae86c 373 PIRSF PIRSF006004 3 366 1.0E-143 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS03545 71dd42868625d47060f64f6b9dbae86c 373 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 4 358 7.6E-159 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS03545 71dd42868625d47060f64f6b9dbae86c 373 SUPERFAMILY SSF102114 103 312 1.96E-12 T 28-03-2018 A6A12_RS08970 edcbc7e8947421d6254fe5a0ee7ace0f 644 PIRSF PIRSF000549 1 644 2.5E-284 T 28-03-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 A6A12_RS08970 edcbc7e8947421d6254fe5a0ee7ace0f 644 SMART SM00763 19 380 2.1E-212 T 28-03-2018 IPR013153 PrkA AAA domain A6A12_RS08970 edcbc7e8947421d6254fe5a0ee7ace0f 644 Pfam PF08298 PrkA AAA domain 20 380 7.6E-171 T 28-03-2018 IPR013153 PrkA AAA domain A6A12_RS08970 edcbc7e8947421d6254fe5a0ee7ace0f 644 Gene3D G3DSA:3.40.50.300 52 355 6.5E-11 T 28-03-2018 A6A12_RS08970 edcbc7e8947421d6254fe5a0ee7ace0f 644 Pfam PF06798 PrkA serine protein kinase C-terminal domain 383 636 1.6E-71 T 28-03-2018 IPR010650 PrkA C-terminal domain A6A12_RS08970 edcbc7e8947421d6254fe5a0ee7ace0f 644 SUPERFAMILY SSF52540 73 145 6.7E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS08970 edcbc7e8947421d6254fe5a0ee7ace0f 644 SUPERFAMILY SSF52540 236 368 6.7E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 SUPERFAMILY SSF158842 2067 2204 3.01E-32 T 28-03-2018 A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF11647 Membrane Localization Domain 2083 2151 1.8E-22 T 28-03-2018 IPR020972 Dermonecrotic/RTX toxin, membrane localization domain A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF11647 Membrane Localization Domain 2231 2294 4.4E-22 T 28-03-2018 IPR020972 Dermonecrotic/RTX toxin, membrane localization domain A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Gene3D G3DSA:2.60.120.260 1457 1619 3.9E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 972 984 7.8 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 644 658 3.4 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 141 157 0.0066 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 741 753 19.0 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 187 204 2.7 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 664 677 37.0 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 858 874 0.43 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 1125 1142 0.086 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 839 855 0.19 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 121 135 0.32 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 915 932 0.58 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 877 891 0.17 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 275 291 0.011 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 1184 1199 0.035 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 1201 1217 0.003 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 1144 1159 0.051 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 1163 1179 0.56 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 1110 1122 5.8 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 801 816 0.046 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 934 950 8.0 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 1296 1313 0.072 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 207 224 0.48 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 1315 1332 20.0 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 896 910 3.5 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 255 272 3.1 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 759 771 2.2 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 161 183 0.0011 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 782 798 0.16 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 953 968 0.13 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 1220 1236 3.1 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 1031 1043 0.36 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 1087 1102 0.23 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 1258 1275 0.011 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 991 1006 0.1 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 1067 1079 4.9 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 1242 1256 35.0 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 820 835 0.074 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 624 641 0.0062 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF07634 RtxA repeat 604 620 20.0 T 28-03-2018 IPR011509 RtxA toxin A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Gene3D G3DSA:3.90.1760.10 2665 2815 2.7E-41 T 28-03-2018 IPR005165 Anthrax toxin, edema factor, central GO:0005576|GO:0008294|GO:0009405 KEGG: 00230+4.6.1.1 A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 SUPERFAMILY SSF56399 2384 2543 2.24E-19 T 28-03-2018 A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 SUPERFAMILY SSF51120 4061 4258 2.49E-12 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF03497 Anthrax toxin LF subunit 2638 2806 1.9E-29 T 28-03-2018 IPR005165 Anthrax toxin, edema factor, central GO:0005576|GO:0008294|GO:0009405 KEGG: 00230+4.6.1.1 A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF11713 Peptidase C80 family 3256 3413 8.2E-53 T 28-03-2018 IPR020974 CGT/MARTX, cysteine protease (CPD) domain A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Gene3D G3DSA:3.90.176.10 2251 2552 1.1E-26 T 28-03-2018 A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 SUPERFAMILY SSF81298 2637 2978 3.01E-66 T 28-03-2018 IPR035099 Anthrax toxin, edema factor, C-terminal KEGG: 00230+4.6.1.1 A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Gene3D G3DSA:2.150.10.10 3883 4070 1.7E-4 T 28-03-2018 A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Gene3D G3DSA:2.150.10.10 4071 4277 1.6E-6 T 28-03-2018 A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 Pfam PF03496 ADP-ribosyltransferase exoenzyme 2398 2543 4.1E-8 T 28-03-2018 IPR003540 ADP ribosyltransferase GO:0005576|GO:0009405 A6A12_RS08040 90da9f3710d53654aab4d87e4883dc4d 4339 SUPERFAMILY SSF158842 2218 2338 1.96E-29 T 28-03-2018 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 SUPERFAMILY SSF56507 903 1225 5.1E-131 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 SUPERFAMILY SSF52242 745 896 1.7E-45 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 PIRSF PIRSF000381 3 1197 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 TIGRFAM TIGR02082 metH: methionine synthase 13 1194 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 SUPERFAMILY SSF82282 8 400 8.5E-117 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 Gene3D G3DSA:3.40.50.280 733 905 4.4E-57 T 28-03-2018 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 SUPERFAMILY SSF47644 654 738 8.37E-30 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 Gene3D G3DSA:3.20.20.20 346 645 5.6E-73 T 28-03-2018 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 Pfam PF02574 Homocysteine S-methyltransferase 18 326 5.6E-80 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 Pfam PF00809 Pterin binding enzyme 361 599 3.8E-59 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 Pfam PF02310 B12 binding domain 749 842 8.7E-18 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 Gene3D G3DSA:1.10.1240.10 653 732 3.8E-38 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 940 1210 2.0E-124 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 SUPERFAMILY SSF51717 357 631 2.35E-88 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 Gene3D G3DSA:3.10.196.10 1083 1225 1.1E-61 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 Gene3D G3DSA:3.10.196.10 958 1082 7.2E-44 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 Pfam PF02607 B12 binding domain 660 734 1.1E-26 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 SMART SM01018 658 741 2.1E-45 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS01515 fa0b56d6e344c2fe285138c0dfd517a5 1225 Gene3D G3DSA:3.20.20.330 1 342 3.7E-110 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A6A12_RS06595 e34633aae597a65e1100a9c8372b5608 664 Gene3D G3DSA:2.30.42.10 247 328 5.8E-13 T 28-03-2018 A6A12_RS06595 e34633aae597a65e1100a9c8372b5608 664 SMART SM00228 247 324 1.9E-7 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS06595 e34633aae597a65e1100a9c8372b5608 664 Gene3D G3DSA:3.90.226.10 329 624 2.5E-57 T 28-03-2018 A6A12_RS06595 e34633aae597a65e1100a9c8372b5608 664 Pfam PF08180 B melanoma antigen family 9 37 1.2E-13 T 28-03-2018 IPR012530 B melanoma antigen A6A12_RS06595 e34633aae597a65e1100a9c8372b5608 664 SUPERFAMILY SSF52096 166 265 1.18E-72 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS06595 e34633aae597a65e1100a9c8372b5608 664 SUPERFAMILY SSF52096 351 540 1.18E-72 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS06595 e34633aae597a65e1100a9c8372b5608 664 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 240 321 6.9E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS06595 e34633aae597a65e1100a9c8372b5608 664 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 531 663 1.1E-40 T 28-03-2018 IPR020992 Tail specific protease, C-terminal A6A12_RS06595 e34633aae597a65e1100a9c8372b5608 664 Gene3D G3DSA:3.30.750.44 156 246 9.2E-24 T 28-03-2018 A6A12_RS06595 e34633aae597a65e1100a9c8372b5608 664 SMART SM00245 327 528 7.4E-68 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A6A12_RS06595 e34633aae597a65e1100a9c8372b5608 664 Pfam PF03572 Peptidase family S41 357 526 1.4E-52 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 A6A12_RS06595 e34633aae597a65e1100a9c8372b5608 664 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 196 548 2.6E-114 T 28-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 A6A12_RS06595 e34633aae597a65e1100a9c8372b5608 664 SUPERFAMILY SSF50156 218 338 1.44E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS08080 168280d6b2932f3657db84b91e64049a 455 SUPERFAMILY SSF118215 29 441 2.88E-90 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS08080 168280d6b2932f3657db84b91e64049a 455 Gene3D G3DSA:1.10.3860.10 18 447 5.8E-86 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS08080 168280d6b2932f3657db84b91e64049a 455 PRINTS PR00173 Glutamate-aspartate symporter signature 75 95 4.9E-28 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS08080 168280d6b2932f3657db84b91e64049a 455 PRINTS PR00173 Glutamate-aspartate symporter signature 259 278 4.9E-28 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS08080 168280d6b2932f3657db84b91e64049a 455 PRINTS PR00173 Glutamate-aspartate symporter signature 105 130 4.9E-28 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS08080 168280d6b2932f3657db84b91e64049a 455 PRINTS PR00173 Glutamate-aspartate symporter signature 396 416 4.9E-28 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS08080 168280d6b2932f3657db84b91e64049a 455 PRINTS PR00173 Glutamate-aspartate symporter signature 27 47 4.9E-28 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS08080 168280d6b2932f3657db84b91e64049a 455 PRINTS PR00173 Glutamate-aspartate symporter signature 181 203 4.9E-28 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS08080 168280d6b2932f3657db84b91e64049a 455 PRINTS PR00173 Glutamate-aspartate symporter signature 369 388 4.9E-28 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS08080 168280d6b2932f3657db84b91e64049a 455 Pfam PF00375 Sodium:dicarboxylate symporter family 32 441 2.0E-98 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 Pfam PF00696 Amino acid kinase family 2 284 4.0E-50 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 SUPERFAMILY SSF51735 463 636 5.91E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 660 682 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 SUPERFAMILY SSF55021 383 476 1.34E-21 T 28-03-2018 A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 SUPERFAMILY SSF55021 303 381 3.97E-22 T 28-03-2018 A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 Gene3D G3DSA:3.40.1160.10 1 290 9.3E-61 T 28-03-2018 A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 SUPERFAMILY SSF55347 614 797 3.92E-48 T 28-03-2018 A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 PIRSF PIRSF000727 1 817 0.0 T 28-03-2018 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+2.7.2.4+1.1.1.3|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4+1.1.1.3|KEGG: 00300+2.7.2.4+1.1.1.3|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 Pfam PF13840 ACT domain 394 456 1.9E-7 T 28-03-2018 IPR027795 GATS-like ACT domain A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 Pfam PF00742 Homoserine dehydrogenase 614 810 1.0E-46 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 SUPERFAMILY SSF53633 1 298 6.17E-76 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 472 606 2.0E-26 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 460 1.5E-132 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 Gene3D G3DSA:3.40.50.720 465 635 2.3E-29 T 28-03-2018 A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 Gene3D G3DSA:3.30.70.260 384 464 4.7E-19 T 28-03-2018 A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 Gene3D G3DSA:3.30.70.260 291 383 4.0E-24 T 28-03-2018 A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 Gene3D G3DSA:3.30.360.10 636 793 1.0E-50 T 28-03-2018 A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS11375 30ff10c92832f245e3f80ac8a951afad 819 Pfam PF01842 ACT domain 324 380 3.1E-9 T 28-03-2018 IPR002912 ACT domain A6A12_RS00860 329d1e55f5bb7308aca581d9cca105b8 677 PRINTS PR00811 Bacterial general secretion pathway protein D signature 483 493 7.1E-37 T 28-03-2018 IPR001775 GspD/PilQ family A6A12_RS00860 329d1e55f5bb7308aca581d9cca105b8 677 PRINTS PR00811 Bacterial general secretion pathway protein D signature 345 355 7.1E-37 T 28-03-2018 IPR001775 GspD/PilQ family A6A12_RS00860 329d1e55f5bb7308aca581d9cca105b8 677 PRINTS PR00811 Bacterial general secretion pathway protein D signature 448 472 7.1E-37 T 28-03-2018 IPR001775 GspD/PilQ family A6A12_RS00860 329d1e55f5bb7308aca581d9cca105b8 677 PRINTS PR00811 Bacterial general secretion pathway protein D signature 578 596 7.1E-37 T 28-03-2018 IPR001775 GspD/PilQ family A6A12_RS00860 329d1e55f5bb7308aca581d9cca105b8 677 PRINTS PR00811 Bacterial general secretion pathway protein D signature 601 615 7.1E-37 T 28-03-2018 IPR001775 GspD/PilQ family A6A12_RS00860 329d1e55f5bb7308aca581d9cca105b8 677 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 559 592 - T 28-03-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 A6A12_RS00860 329d1e55f5bb7308aca581d9cca105b8 677 Pfam PF00263 Bacterial type II and III secretion system protein 452 614 2.3E-51 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 A6A12_RS00860 329d1e55f5bb7308aca581d9cca105b8 677 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 30 623 6.7E-161 T 28-03-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 A6A12_RS00860 329d1e55f5bb7308aca581d9cca105b8 677 Pfam PF03958 Bacterial type II/III secretion system short domain 126 187 9.4E-9 T 28-03-2018 IPR005644 NolW-like A6A12_RS00860 329d1e55f5bb7308aca581d9cca105b8 677 Pfam PF03958 Bacterial type II/III secretion system short domain 192 259 2.2E-14 T 28-03-2018 IPR005644 NolW-like A6A12_RS00860 329d1e55f5bb7308aca581d9cca105b8 677 Pfam PF03958 Bacterial type II/III secretion system short domain 267 345 3.4E-18 T 28-03-2018 IPR005644 NolW-like A6A12_RS00860 329d1e55f5bb7308aca581d9cca105b8 677 PRINTS PR01032 Gene IV protein signature 425 448 7.1E-9 T 28-03-2018 A6A12_RS00860 329d1e55f5bb7308aca581d9cca105b8 677 PRINTS PR01032 Gene IV protein signature 541 569 7.1E-9 T 28-03-2018 A6A12_RS00860 329d1e55f5bb7308aca581d9cca105b8 677 PRINTS PR01032 Gene IV protein signature 594 616 7.1E-9 T 28-03-2018 A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 Pfam PF14842 FliG N-terminal domain 22 122 1.8E-27 T 28-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 Gene3D G3DSA:1.10.220.30 14 86 7.1E-10 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 SUPERFAMILY SSF48029 131 342 1.44E-66 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 PRINTS PR00954 Flagellar motor switch protein FliG signature 131 154 1.6E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 PRINTS PR00954 Flagellar motor switch protein FliG signature 243 263 1.6E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 PRINTS PR00954 Flagellar motor switch protein FliG signature 51 77 1.6E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 PRINTS PR00954 Flagellar motor switch protein FliG signature 212 237 1.6E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 PRINTS PR00954 Flagellar motor switch protein FliG signature 22 38 1.6E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 PRINTS PR00954 Flagellar motor switch protein FliG signature 265 285 1.6E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 PRINTS PR00954 Flagellar motor switch protein FliG signature 289 315 1.6E-58 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 Pfam PF14841 FliG middle domain 132 204 9.6E-25 T 28-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 SUPERFAMILY SSF48029 24 134 1.23E-19 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 PIRSF PIRSF003161 16 349 4.4E-111 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 Pfam PF01706 FliG C-terminal domain 235 341 3.0E-41 T 28-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 18 347 1.1E-93 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 Gene3D G3DSA:1.10.220.30 212 349 6.0E-33 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A6A12_RS10215 7ae8266ba0fb519bf9ba537f87eb7598 349 Gene3D G3DSA:1.10.220.30 87 210 1.0E-20 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical A6A12_RS03395 3959bd176b54655e2d0c0cefa8ae70f5 319 SUPERFAMILY SSF53850 32 315 1.51E-66 T 28-03-2018 A6A12_RS03395 3959bd176b54655e2d0c0cefa8ae70f5 319 Gene3D G3DSA:3.40.190.10 37 170 6.0E-25 T 28-03-2018 A6A12_RS03395 3959bd176b54655e2d0c0cefa8ae70f5 319 Gene3D G3DSA:3.40.190.10 171 318 1.1E-25 T 28-03-2018 A6A12_RS03395 3959bd176b54655e2d0c0cefa8ae70f5 319 Pfam PF12849 PBP superfamily domain 32 290 2.4E-31 T 28-03-2018 IPR024370 PBP domain A6A12_RS03395 3959bd176b54655e2d0c0cefa8ae70f5 319 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 18 304 4.2E-76 T 28-03-2018 IPR011862 Phosphate binding protein GO:0006810 A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 Pfam PF08275 DNA primase catalytic core, N-terminal domain 131 255 4.1E-41 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 SMART SM00766 450 575 3.6E-53 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 SUPERFAMILY SSF57783 4 101 5.44E-38 T 28-03-2018 A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 Gene3D G3DSA:3.90.980.10 114 245 4.9E-45 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 Pfam PF01807 CHC2 zinc finger 6 101 2.3E-41 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 SUPERFAMILY SSF117023 447 578 7.72E-45 T 28-03-2018 A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 Gene3D G3DSA:1.20.50.20 373 426 1.1E-15 T 28-03-2018 A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 Gene3D G3DSA:1.10.860.10 434 580 9.2E-40 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 Gene3D G3DSA:3.40.1360.10 246 372 1.7E-30 T 28-03-2018 A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 SMART SM00493 264 335 2.0E-19 T 28-03-2018 IPR006171 TOPRIM domain A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 SUPERFAMILY SSF56731 120 428 8.37E-111 T 28-03-2018 A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 SMART SM00400 36 90 7.2E-37 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 Hamap MF_00974 DNA primase [dnaG]. 4 576 29.289 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 Pfam PF08278 DNA primase DnaG DnaB-binding 451 574 1.6E-35 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 Pfam PF13155 Toprim-like 268 355 1.7E-13 T 28-03-2018 A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 Gene3D G3DSA:3.90.580.10 1 103 2.6E-36 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 TIGRFAM TIGR01391 dnaG: DNA primase 5 423 1.3E-148 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 PIRSF PIRSF002811 2 580 1.6E-143 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 A6A12_RS02335 e3c44792e95cc26adb85517827e25d73 580 Pfam PF10410 DnaB-helicase binding domain of primase 375 426 6.5E-9 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 A6A12_RS05245 f884aa37a2195917bfc24d4e7f0fbe69 231 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 3 231 39.927 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS05245 f884aa37a2195917bfc24d4e7f0fbe69 231 SMART SM00934 5 226 5.8E-97 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS05245 f884aa37a2195917bfc24d4e7f0fbe69 231 SUPERFAMILY SSF51366 1 228 1.38E-75 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A6A12_RS05245 f884aa37a2195917bfc24d4e7f0fbe69 231 Gene3D G3DSA:3.20.20.70 1 231 1.6E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS05245 f884aa37a2195917bfc24d4e7f0fbe69 231 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 5 225 4.9E-51 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS05245 f884aa37a2195917bfc24d4e7f0fbe69 231 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 6 226 1.6E-59 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS05245 f884aa37a2195917bfc24d4e7f0fbe69 231 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 57 70 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS04875 e3051a5f5e0df724df4ce1fcf1e16c83 707 Gene3D G3DSA:1.10.1040.10 497 595 1.2E-24 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A6A12_RS04875 e3051a5f5e0df724df4ce1fcf1e16c83 707 Gene3D G3DSA:1.10.1040.10 613 704 9.6E-18 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A6A12_RS04875 e3051a5f5e0df724df4ce1fcf1e16c83 707 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 497 590 3.5E-26 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A6A12_RS04875 e3051a5f5e0df724df4ce1fcf1e16c83 707 Gene3D G3DSA:3.40.50.720 258 496 2.9E-54 T 28-03-2018 A6A12_RS04875 e3051a5f5e0df724df4ce1fcf1e16c83 707 SUPERFAMILY SSF48179 497 596 2.55E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A6A12_RS04875 e3051a5f5e0df724df4ce1fcf1e16c83 707 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 203 5.1E-36 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A6A12_RS04875 e3051a5f5e0df724df4ce1fcf1e16c83 707 Gene3D G3DSA:3.90.226.10 2 206 5.1E-51 T 28-03-2018 A6A12_RS04875 e3051a5f5e0df724df4ce1fcf1e16c83 707 SUPERFAMILY SSF48179 613 706 2.13E-23 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A6A12_RS04875 e3051a5f5e0df724df4ce1fcf1e16c83 707 Hamap MF_01617 Fatty acid oxidation complex subunit alpha [fadJ]. 1 706 51.758 T 28-03-2018 IPR012802 Fatty oxidation complex, alpha subunit FadJ GO:0003857|GO:0004300|GO:0006635|GO:0008692|GO:0051287|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A6A12_RS04875 e3051a5f5e0df724df4ce1fcf1e16c83 707 SUPERFAMILY SSF51735 312 495 9.92E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS04875 e3051a5f5e0df724df4ce1fcf1e16c83 707 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 316 495 2.4E-53 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A6A12_RS04875 e3051a5f5e0df724df4ce1fcf1e16c83 707 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 494 519 - T 28-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A6A12_RS04875 e3051a5f5e0df724df4ce1fcf1e16c83 707 SUPERFAMILY SSF52096 3 305 5.75E-64 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS04875 e3051a5f5e0df724df4ce1fcf1e16c83 707 TIGRFAM TIGR02440 FadJ: fatty oxidation complex, alpha subunit FadJ 6 706 0.0 T 28-03-2018 IPR012802 Fatty oxidation complex, alpha subunit FadJ GO:0003857|GO:0004300|GO:0006635|GO:0008692|GO:0051287|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A6A12_RS04875 e3051a5f5e0df724df4ce1fcf1e16c83 707 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 Gene3D G3DSA:3.40.50.300 2 74 4.1E-11 T 28-03-2018 A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 2.6E-16 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 59.185 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 393 6.5E-230 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 SUPERFAMILY SSF50447 205 301 1.16E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 Gene3D G3DSA:2.40.30.10 300 393 9.3E-34 T 28-03-2018 A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 1.7E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 Gene3D G3DSA:3.40.50.300 75 203 9.2E-32 T 28-03-2018 A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 Gene3D G3DSA:2.40.30.10 206 299 2.1E-29 T 28-03-2018 A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 SUPERFAMILY SSF52540 6 219 5.81E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 SUPERFAMILY SSF50465 298 393 3.17E-35 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 2.1E-58 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 4.7E-33 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.5E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.5E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.5E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.5E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS01375 f281005c3475ab77521fde75ba4744ee 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.5E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS00875 efdfd6def6413cdd131ac29163b5173d 147 Gene3D G3DSA:3.30.700.10 24 141 5.2E-31 T 28-03-2018 A6A12_RS00875 efdfd6def6413cdd131ac29163b5173d 147 PRINTS PR00813 Bacterial general secretion pathway protein G signature 46 64 4.2E-22 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 A6A12_RS00875 efdfd6def6413cdd131ac29163b5173d 147 PRINTS PR00813 Bacterial general secretion pathway protein G signature 10 35 4.2E-22 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 A6A12_RS00875 efdfd6def6413cdd131ac29163b5173d 147 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 30 9.8E-10 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS00875 efdfd6def6413cdd131ac29163b5173d 147 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 31 3.9E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS00875 efdfd6def6413cdd131ac29163b5173d 147 Pfam PF08334 Type II secretion system (T2SS), protein G 33 141 1.2E-42 T 28-03-2018 IPR013545 Type II secretion system protein G A6A12_RS00875 efdfd6def6413cdd131ac29163b5173d 147 SUPERFAMILY SSF54523 36 142 1.2E-38 T 28-03-2018 A6A12_RS00875 efdfd6def6413cdd131ac29163b5173d 147 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS00875 efdfd6def6413cdd131ac29163b5173d 147 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 9 142 1.1E-58 T 28-03-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 A6A12_RS00595 cf742b910054624db0ab9836c152303a 272 Pfam PF04072 Leucine carboxyl methyltransferase 72 131 3.8E-6 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 A6A12_RS00595 cf742b910054624db0ab9836c152303a 272 Gene3D G3DSA:3.40.50.150 1 217 2.4E-21 T 28-03-2018 A6A12_RS00595 cf742b910054624db0ab9836c152303a 272 PIRSF PIRSF028177 6 272 1.6E-72 T 28-03-2018 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 A6A12_RS00595 cf742b910054624db0ab9836c152303a 272 SUPERFAMILY SSF53335 20 258 8.31E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS00565 83efbcab5a579c240c29177a322d7467 277 SUPERFAMILY SSF144091 96 269 1.83E-40 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A6A12_RS00565 83efbcab5a579c240c29177a322d7467 277 Pfam PF01694 Rhomboid family 134 268 1.6E-31 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A6A12_RS00565 83efbcab5a579c240c29177a322d7467 277 Gene3D G3DSA:1.20.1540.10 94 269 8.4E-34 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A6A12_RS00565 83efbcab5a579c240c29177a322d7467 277 TIGRFAM TIGR04239 rhombo_GlpG: rhomboid family protease GlpG 3 271 2.5E-119 T 28-03-2018 IPR023662 Rhomboid protease GlpG GO:0004252|GO:0006508|GO:0016021 A6A12_RS00565 83efbcab5a579c240c29177a322d7467 277 Pfam PF12122 Cytoplasmic N-terminal domain of rhomboid serine protease 1 87 3.7E-32 T 28-03-2018 IPR022732 Peptidase S54, GlpG peptidase, N-terminal GO:0004252|GO:0016021 A6A12_RS04305 2f8ecd08d329cc6bfa9f139cdbc69c54 172 Gene3D G3DSA:3.30.1950.10 27 88 1.0E-18 T 28-03-2018 A6A12_RS04305 2f8ecd08d329cc6bfa9f139cdbc69c54 172 Gene3D G3DSA:3.10.560.10 89 169 1.7E-13 T 28-03-2018 A6A12_RS04305 2f8ecd08d329cc6bfa9f139cdbc69c54 172 Pfam PF10531 SLBB domain 100 140 6.1E-7 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A6A12_RS04305 2f8ecd08d329cc6bfa9f139cdbc69c54 172 Pfam PF02563 Polysaccharide biosynthesis/export protein 19 93 1.5E-20 T 28-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 A6A12_RS04150 4eb994f34d0f447b97bc40e3c1c7f5dd 114 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 37 108 1.9E-19 T 28-03-2018 IPR018660 C-type lysozyme inhibitor A6A12_RS04150 4eb994f34d0f447b97bc40e3c1c7f5dd 114 SUPERFAMILY SSF141488 35 111 3.4E-15 T 28-03-2018 IPR018660 C-type lysozyme inhibitor A6A12_RS01725 56ce666d1cbd189a9ccc267b2e7bb58c 322 Gene3D G3DSA:3.40.190.10 172 321 2.7E-41 T 28-03-2018 A6A12_RS01725 56ce666d1cbd189a9ccc267b2e7bb58c 322 Pfam PF16868 NMT1-like family 30 319 1.0E-96 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family A6A12_RS01725 56ce666d1cbd189a9ccc267b2e7bb58c 322 SUPERFAMILY SSF53850 25 321 6.09E-90 T 28-03-2018 A6A12_RS01725 56ce666d1cbd189a9ccc267b2e7bb58c 322 Gene3D G3DSA:3.40.190.10 22 164 3.4E-27 T 28-03-2018 A6A12_RS01725 56ce666d1cbd189a9ccc267b2e7bb58c 322 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 10 319 2.1E-114 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family A6A12_RS12910 87c27c3a95d7835943115a92a0a66f46 71 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 31.787 T 28-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12910 87c27c3a95d7835943115a92a0a66f46 71 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12910 87c27c3a95d7835943115a92a0a66f46 71 SUPERFAMILY SSF143800 1 68 1.45E-27 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12910 87c27c3a95d7835943115a92a0a66f46 71 Pfam PF01197 Ribosomal protein L31 1 66 5.7E-32 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12910 87c27c3a95d7835943115a92a0a66f46 71 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 67 1.7E-35 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12910 87c27c3a95d7835943115a92a0a66f46 71 PRINTS PR01249 Ribosomal protein L31 signature 2 19 3.5E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12910 87c27c3a95d7835943115a92a0a66f46 71 PRINTS PR01249 Ribosomal protein L31 signature 32 47 3.5E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12910 87c27c3a95d7835943115a92a0a66f46 71 PRINTS PR01249 Ribosomal protein L31 signature 47 65 3.5E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS13125 5a7d454e22a0839d290d5f87533b0214 132 Pfam PF09278 MerR, DNA binding 46 109 4.5E-17 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding A6A12_RS13125 5a7d454e22a0839d290d5f87533b0214 132 SUPERFAMILY SSF46955 2 121 1.76E-32 T 28-03-2018 IPR009061 Putative DNA-binding domain A6A12_RS13125 5a7d454e22a0839d290d5f87533b0214 132 SMART SM00422 2 71 1.4E-28 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A6A12_RS13125 5a7d454e22a0839d290d5f87533b0214 132 Gene3D G3DSA:1.10.1660.10 59 132 2.8E-18 T 28-03-2018 A6A12_RS13125 5a7d454e22a0839d290d5f87533b0214 132 TIGRFAM TIGR02043 ZntR: Zn(II)-responsive transcriptional regulator 1 132 1.7E-64 T 28-03-2018 IPR011788 Zn(II)-responsive transcriptional regulator GO:0003677|GO:0006351|GO:0008270 A6A12_RS13125 5a7d454e22a0839d290d5f87533b0214 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 2.9E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A6A12_RS13125 5a7d454e22a0839d290d5f87533b0214 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 2.9E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A6A12_RS13125 5a7d454e22a0839d290d5f87533b0214 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 2.9E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A6A12_RS13125 5a7d454e22a0839d290d5f87533b0214 132 Gene3D G3DSA:1.10.1660.10 1 58 3.4E-21 T 28-03-2018 A6A12_RS13125 5a7d454e22a0839d290d5f87533b0214 132 Pfam PF00376 MerR family regulatory protein 4 40 9.3E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A6A12_RS08120 890ea0256420a1827647c1d4c72e4d08 215 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 3 215 1.5E-75 T 28-03-2018 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 A6A12_RS08120 890ea0256420a1827647c1d4c72e4d08 215 TIGRFAM TIGR03840 TMPT_Se_Te: thiopurine S-methyltransferase, Se/Te detoxification family 5 214 2.0E-79 T 28-03-2018 IPR022474 Thiopurine S-methyltransferase, Se/Te detoxification GO:0008119|GO:0010038|GO:0032259 KEGG: 00983+2.1.1.67 A6A12_RS08120 890ea0256420a1827647c1d4c72e4d08 215 Gene3D G3DSA:3.40.50.150 17 215 6.8E-22 T 28-03-2018 A6A12_RS08120 890ea0256420a1827647c1d4c72e4d08 215 PIRSF PIRSF023956 1 215 1.4E-74 T 28-03-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 A6A12_RS08120 890ea0256420a1827647c1d4c72e4d08 215 SUPERFAMILY SSF53335 3 214 6.44E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS08120 890ea0256420a1827647c1d4c72e4d08 215 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 2 215 36.347 T 28-03-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 A6A12_RS02260 92217a2d8a7c42fc0b90ff67cc79ff23 196 SMART SM00857 4 146 2.5E-44 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A6A12_RS02260 92217a2d8a7c42fc0b90ff67cc79ff23 196 ProSitePatterns PS00398 Site-specific recombinases signature 2. 64 76 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A6A12_RS02260 92217a2d8a7c42fc0b90ff67cc79ff23 196 SUPERFAMILY SSF53041 3 146 9.94E-36 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A6A12_RS02260 92217a2d8a7c42fc0b90ff67cc79ff23 196 Gene3D G3DSA:3.40.50.1390 1 115 6.2E-28 T 28-03-2018 A6A12_RS02260 92217a2d8a7c42fc0b90ff67cc79ff23 196 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A6A12_RS02260 92217a2d8a7c42fc0b90ff67cc79ff23 196 Pfam PF00239 Resolvase, N terminal domain 5 145 1.7E-35 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A6A12_RS02260 92217a2d8a7c42fc0b90ff67cc79ff23 196 Gene3D G3DSA:1.20.5.40 116 144 2.6E-15 T 28-03-2018 A6A12_RS02260 92217a2d8a7c42fc0b90ff67cc79ff23 196 Gene3D G3DSA:1.10.10.60 146 190 9.0E-11 T 28-03-2018 A6A12_RS12535 101eb0a76b1f9a042aca134b352b1b55 432 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 432 219.116 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A6A12_RS12535 101eb0a76b1f9a042aca134b352b1b55 432 SUPERFAMILY SSF52540 3 430 7.97E-182 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12535 101eb0a76b1f9a042aca134b352b1b55 432 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A6A12_RS12535 101eb0a76b1f9a042aca134b352b1b55 432 SMART SM00788 4 425 0.0 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A6A12_RS12535 101eb0a76b1f9a042aca134b352b1b55 432 Gene3D G3DSA:3.40.440.10 153 266 1.3E-25 T 28-03-2018 A6A12_RS12535 101eb0a76b1f9a042aca134b352b1b55 432 Gene3D G3DSA:3.40.440.10 1 152 1.4E-55 T 28-03-2018 A6A12_RS12535 101eb0a76b1f9a042aca134b352b1b55 432 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 425 4.9E-194 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A6A12_RS12535 101eb0a76b1f9a042aca134b352b1b55 432 Pfam PF00709 Adenylosuccinate synthetase 5 424 1.0E-181 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A6A12_RS12535 101eb0a76b1f9a042aca134b352b1b55 432 Gene3D G3DSA:3.90.170.10 267 432 2.8E-68 T 28-03-2018 A6A12_RS12535 101eb0a76b1f9a042aca134b352b1b55 432 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A6A12_RS01275 5df19561df51393b5b0543fd48f6c3aa 376 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 3 311 50.925 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 A6A12_RS01275 5df19561df51393b5b0543fd48f6c3aa 376 Gene3D G3DSA:3.30.70.20 196 366 3.8E-10 T 28-03-2018 A6A12_RS01275 5df19561df51393b5b0543fd48f6c3aa 376 Gene3D G3DSA:3.30.70.20 90 195 7.8E-5 T 28-03-2018 A6A12_RS01275 5df19561df51393b5b0543fd48f6c3aa 376 Pfam PF13484 4Fe-4S double cluster binding domain 188 252 1.9E-20 T 28-03-2018 A6A12_RS01275 5df19561df51393b5b0543fd48f6c3aa 376 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 10 343 1.8E-151 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 A6A12_RS01275 5df19561df51393b5b0543fd48f6c3aa 376 Pfam PF08331 Domain of unknown function (DUF1730) 58 136 1.3E-23 T 28-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 A6A12_RS01275 5df19561df51393b5b0543fd48f6c3aa 376 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 189 200 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A6A12_RS01275 5df19561df51393b5b0543fd48f6c3aa 376 SUPERFAMILY SSF54862 165 281 2.89E-19 T 28-03-2018 A6A12_RS12255 a78251010f24d0573c765928c742ceb2 212 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 44 197 1.3E-69 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A6A12_RS12255 a78251010f24d0573c765928c742ceb2 212 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 42 203 38.749 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A6A12_RS12255 a78251010f24d0573c765928c742ceb2 212 Gene3D G3DSA:3.30.1060.10 24 202 7.4E-80 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A6A12_RS12255 a78251010f24d0573c765928c742ceb2 212 Pfam PF01625 Peptide methionine sulfoxide reductase 44 197 1.7E-68 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A6A12_RS12255 a78251010f24d0573c765928c742ceb2 212 SUPERFAMILY SSF55068 3 206 1.7E-79 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 A6A12_RS12800 481221e850204d17de56edc42d04add0 252 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A6A12_RS12800 481221e850204d17de56edc42d04add0 252 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A6A12_RS12800 481221e850204d17de56edc42d04add0 252 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 9 111 1.1E-33 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS12800 481221e850204d17de56edc42d04add0 252 SUPERFAMILY SSF46548 107 226 2.62E-30 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A6A12_RS12800 481221e850204d17de56edc42d04add0 252 Gene3D G3DSA:1.10.1060.10 107 241 2.1E-25 T 28-03-2018 A6A12_RS12800 481221e850204d17de56edc42d04add0 252 Gene3D G3DSA:3.10.20.30 1 105 1.5E-30 T 28-03-2018 IPR012675 Beta-grasp domain A6A12_RS12800 481221e850204d17de56edc42d04add0 252 SUPERFAMILY SSF54292 5 106 2.36E-30 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A6A12_RS12800 481221e850204d17de56edc42d04add0 252 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 229 9.6E-96 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS12800 481221e850204d17de56edc42d04add0 252 Pfam PF13183 4Fe-4S dicluster domain 147 219 7.2E-11 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A6A12_RS01955 aa033b87d5488212d0cb0f6917925621 243 SUPERFAMILY SSF88697 2 70 1.17E-18 T 28-03-2018 IPR015947 PUA-like domain A6A12_RS01955 aa033b87d5488212d0cb0f6917925621 243 Pfam PF04452 RNA methyltransferase 19 236 5.4E-75 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS01955 aa033b87d5488212d0cb0f6917925621 243 Gene3D G3DSA:3.40.1280.10 74 243 6.7E-56 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A6A12_RS01955 aa033b87d5488212d0cb0f6917925621 243 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 2 242 3.0E-87 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS01955 aa033b87d5488212d0cb0f6917925621 243 PIRSF PIRSF015601 2 242 5.4E-57 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS01955 aa033b87d5488212d0cb0f6917925621 243 SUPERFAMILY SSF75217 75 242 1.88E-52 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases A6A12_RS01955 aa033b87d5488212d0cb0f6917925621 243 Gene3D G3DSA:2.40.240.20 1 73 2.4E-22 T 28-03-2018 A6A12_RS03555 192f3f82beb505c6610ad26f9bc3ac93 374 SUPERFAMILY SSF56014 265 354 5.89E-11 T 28-03-2018 A6A12_RS03555 192f3f82beb505c6610ad26f9bc3ac93 374 Pfam PF04551 GcpE protein 14 354 3.3E-132 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A6A12_RS03555 192f3f82beb505c6610ad26f9bc3ac93 374 PIRSF PIRSF004640 1 364 7.9E-146 T 28-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A6A12_RS03555 192f3f82beb505c6610ad26f9bc3ac93 374 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 9 351 2.4E-124 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A6A12_RS03555 192f3f82beb505c6610ad26f9bc3ac93 374 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 7 358 34.66 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 A6A12_RS03555 192f3f82beb505c6610ad26f9bc3ac93 374 SUPERFAMILY SSF51604 24 139 9.89E-10 T 28-03-2018 IPR029065 Enolase C-terminal domain-like A6A12_RS03555 192f3f82beb505c6610ad26f9bc3ac93 374 Gene3D G3DSA:3.20.20.120 19 232 8.2E-21 T 28-03-2018 IPR029065 Enolase C-terminal domain-like A6A12_RS13320 95a2942185bb487ab60ca663bd4ea8e4 132 Gene3D G3DSA:2.60.120.10 1 132 3.2E-36 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS13320 95a2942185bb487ab60ca663bd4ea8e4 132 Pfam PF05523 WxcM-like, C-terminal 1 130 4.8E-54 T 28-03-2018 IPR008894 WxcM-like, C-terminal KEGG: 00523+5.3.2.3|MetaCyc: PWY-6953|MetaCyc: PWY-7688 A6A12_RS13320 95a2942185bb487ab60ca663bd4ea8e4 132 SUPERFAMILY SSF51182 2 131 4.33E-45 T 28-03-2018 IPR011051 RmlC-like cupin domain A6A12_RS03505 a703e3428a8c40787a499661f8f47a2b 127 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 6.9E-69 T 28-03-2018 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 A6A12_RS03505 a703e3428a8c40787a499661f8f47a2b 127 SUPERFAMILY SSF82649 1 125 7.06E-48 T 28-03-2018 A6A12_RS03505 a703e3428a8c40787a499661f8f47a2b 127 Gene3D G3DSA:3.90.1010.10 1 127 2.2E-51 T 28-03-2018 A6A12_RS03505 a703e3428a8c40787a499661f8f47a2b 127 Pfam PF01592 NifU-like N terminal domain 2 126 2.5E-56 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 A6A12_RS05215 7ec2e059838ea9bda8853af48ea09f64 99 Pfam PF12836 Helix-hairpin-helix motif 37 97 3.1E-20 T 28-03-2018 A6A12_RS05215 7ec2e059838ea9bda8853af48ea09f64 99 SUPERFAMILY SSF47781 31 99 1.78E-23 T 28-03-2018 IPR010994 RuvA domain 2-like A6A12_RS05215 7ec2e059838ea9bda8853af48ea09f64 99 Gene3D G3DSA:1.10.150.310 56 99 2.2E-13 T 28-03-2018 A6A12_RS05215 7ec2e059838ea9bda8853af48ea09f64 99 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 37 99 1.4E-23 T 28-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain A6A12_RS05215 7ec2e059838ea9bda8853af48ea09f64 99 Gene3D G3DSA:1.10.150.20 19 55 5.1E-7 T 28-03-2018 A6A12_RS11935 1fa8843c36d663f7f8aae5c9be5bf9a0 515 Pfam PF00682 HMGL-like 4 273 9.0E-102 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A6A12_RS11935 1fa8843c36d663f7f8aae5c9be5bf9a0 515 Pfam PF08502 LeuA allosteric (dimerisation) domain 369 498 9.9E-30 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A6A12_RS11935 1fa8843c36d663f7f8aae5c9be5bf9a0 515 SUPERFAMILY SSF51569 1 291 5.86E-101 T 28-03-2018 A6A12_RS11935 1fa8843c36d663f7f8aae5c9be5bf9a0 515 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 496 1.4E-236 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A6A12_RS11935 1fa8843c36d663f7f8aae5c9be5bf9a0 515 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 508 42.151 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A6A12_RS11935 1fa8843c36d663f7f8aae5c9be5bf9a0 515 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A6A12_RS11935 1fa8843c36d663f7f8aae5c9be5bf9a0 515 SMART SM00917 369 499 9.3E-28 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A6A12_RS11935 1fa8843c36d663f7f8aae5c9be5bf9a0 515 Gene3D G3DSA:3.20.20.70 1 331 4.3E-111 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS11935 1fa8843c36d663f7f8aae5c9be5bf9a0 515 SUPERFAMILY SSF110921 393 498 2.09E-20 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A6A12_RS11935 1fa8843c36d663f7f8aae5c9be5bf9a0 515 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 A6A12_RS11830 10791206c3266301f20be3c623014b0b 190 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 2 190 1.3E-102 T 28-03-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS11830 10791206c3266301f20be3c623014b0b 190 Pfam PF04542 Sigma-70 region 2 25 92 9.0E-19 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS11830 10791206c3266301f20be3c623014b0b 190 Gene3D G3DSA:1.10.1740.10 1 113 1.1E-31 T 28-03-2018 A6A12_RS11830 10791206c3266301f20be3c623014b0b 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 185 4.0E-33 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS11830 10791206c3266301f20be3c623014b0b 190 SUPERFAMILY SSF88946 2 107 4.87E-33 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS11830 10791206c3266301f20be3c623014b0b 190 Pfam PF08281 Sigma-70, region 4 135 181 7.4E-18 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS11830 10791206c3266301f20be3c623014b0b 190 SUPERFAMILY SSF88659 124 185 1.87E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS11830 10791206c3266301f20be3c623014b0b 190 Gene3D G3DSA:1.10.10.10 114 189 2.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05755 25acec63f4aefc8007a2720dab14a366 195 Pfam PF04994 TfoX C-terminal domain 115 194 1.3E-30 T 28-03-2018 IPR007077 TfoX, C-terminal A6A12_RS05755 25acec63f4aefc8007a2720dab14a366 195 Gene3D G3DSA:1.10.150.20 116 195 3.2E-22 T 28-03-2018 A6A12_RS05755 25acec63f4aefc8007a2720dab14a366 195 SUPERFAMILY SSF159894 6 104 3.4E-30 T 28-03-2018 A6A12_RS05755 25acec63f4aefc8007a2720dab14a366 195 Gene3D G3DSA:3.30.1460.30 1 105 7.0E-22 T 28-03-2018 A6A12_RS05755 25acec63f4aefc8007a2720dab14a366 195 PIRSF PIRSF028788 1 195 1.1E-45 T 28-03-2018 IPR026256 Transcriptional regulator, TfoX/Sxy-type A6A12_RS05755 25acec63f4aefc8007a2720dab14a366 195 Pfam PF04993 TfoX N-terminal domain 12 101 2.2E-28 T 28-03-2018 IPR007076 TfoX, N-terminal A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 334 7.8E-134 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 332 2.1E-57 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 299 322 3.7E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 3.7E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 3.7E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 277 3.7E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 4.0E-32 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 230 240 4.0E-32 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 4.0E-32 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 4.0E-32 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 313 324 4.0E-32 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 2.4E-45 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 335 84.078 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 SUPERFAMILY SSF53671 4 336 1.13E-100 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 Gene3D G3DSA:3.40.50.1370 6 166 5.1E-53 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS13015 bb5353102f72ed9a938e49e3250fff03 336 Gene3D G3DSA:3.40.50.1370 167 336 9.2E-55 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS09335 466d1b102fd85cb8105858d16a2acf74 409 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 363 4.2E-26 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A6A12_RS09335 466d1b102fd85cb8105858d16a2acf74 409 Gene3D G3DSA:3.40.47.10 263 409 7.7E-36 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS09335 466d1b102fd85cb8105858d16a2acf74 409 SUPERFAMILY SSF53901 3 252 8.64E-54 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS09335 466d1b102fd85cb8105858d16a2acf74 409 SMART SM00825 Beta-ketoacyl synthase 5 409 1.9E-10 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A6A12_RS09335 466d1b102fd85cb8105858d16a2acf74 409 SUPERFAMILY SSF53901 216 406 6.59E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS09335 466d1b102fd85cb8105858d16a2acf74 409 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site A6A12_RS09335 466d1b102fd85cb8105858d16a2acf74 409 Gene3D G3DSA:3.40.47.10 5 260 1.1E-51 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS09335 466d1b102fd85cb8105858d16a2acf74 409 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 247 2.5E-40 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A6A12_RS13055 e198ed5b849135a1ed5ece939a6986e0 88 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 11 87 8.7E-35 T 28-03-2018 IPR019886 Sodium symporter small subunit, predicted A6A12_RS13055 e198ed5b849135a1ed5ece939a6986e0 88 Pfam PF13937 Domain of unknown function (DUF4212) 9 85 4.4E-34 T 28-03-2018 IPR019886 Sodium symporter small subunit, predicted A6A12_RS04870 3907a031bc476a1c4f0cc074e9c83309 435 SUPERFAMILY SSF53901 296 434 2.2E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS04870 3907a031bc476a1c4f0cc074e9c83309 435 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 16 433 1.3E-127 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A6A12_RS04870 3907a031bc476a1c4f0cc074e9c83309 435 ProSitePatterns PS00737 Thiolases signature 2. 381 397 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A6A12_RS04870 3907a031bc476a1c4f0cc074e9c83309 435 Hamap MF_01618 3-ketoacyl-CoA thiolase [fadI]. 1 435 66.464 T 28-03-2018 IPR012806 Acetyl-CoA C-acyltransferase FadI GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 A6A12_RS04870 3907a031bc476a1c4f0cc074e9c83309 435 PIRSF PIRSF000429 8 435 3.5E-120 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A6A12_RS04870 3907a031bc476a1c4f0cc074e9c83309 435 Gene3D G3DSA:3.40.47.10 290 432 1.0E-24 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS04870 3907a031bc476a1c4f0cc074e9c83309 435 TIGRFAM TIGR02446 FadI: acetyl-CoA C-acyltransferase FadI 6 435 6.4E-267 T 28-03-2018 IPR012806 Acetyl-CoA C-acyltransferase FadI GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 A6A12_RS04870 3907a031bc476a1c4f0cc074e9c83309 435 SUPERFAMILY SSF53901 14 294 2.99E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS04870 3907a031bc476a1c4f0cc074e9c83309 435 Pfam PF00108 Thiolase, N-terminal domain 14 286 3.3E-61 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A6A12_RS04870 3907a031bc476a1c4f0cc074e9c83309 435 Gene3D G3DSA:3.40.47.10 11 289 4.7E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS04870 3907a031bc476a1c4f0cc074e9c83309 435 Pfam PF02803 Thiolase, C-terminal domain 295 433 4.8E-35 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A6A12_RS07105 9143816911f880628a6946d012060e32 678 SUPERFAMILY SSF52467 220 406 1.21E-39 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A6A12_RS07105 9143816911f880628a6946d012060e32 678 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 510 529 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A6A12_RS07105 9143816911f880628a6946d012060e32 678 SUPERFAMILY SSF52518 451 661 2.14E-53 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS07105 9143816911f880628a6946d012060e32 678 Gene3D G3DSA:3.40.50.970 444 650 1.0E-39 T 28-03-2018 A6A12_RS07105 9143816911f880628a6946d012060e32 678 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 474 633 1.6E-39 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A6A12_RS07105 9143816911f880628a6946d012060e32 678 Gene3D G3DSA:3.40.50.970 36 244 8.5E-46 T 28-03-2018 A6A12_RS07105 9143816911f880628a6946d012060e32 678 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 254 385 2.2E-30 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A6A12_RS07105 9143816911f880628a6946d012060e32 678 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 40 675 2.1E-283 T 28-03-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 A6A12_RS07105 9143816911f880628a6946d012060e32 678 Gene3D G3DSA:3.40.50.1220 245 422 9.2E-32 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A6A12_RS07105 9143816911f880628a6946d012060e32 678 SUPERFAMILY SSF52518 35 244 1.77E-33 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS07105 9143816911f880628a6946d012060e32 678 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 41 228 1.2E-30 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A6A12_RS08290 21b296c43a495773b549fff4e450780c 208 Gene3D G3DSA:1.10.357.10 51 208 4.5E-28 T 28-03-2018 A6A12_RS08290 21b296c43a495773b549fff4e450780c 208 Gene3D G3DSA:1.10.10.60 1 50 2.6E-18 T 28-03-2018 A6A12_RS08290 21b296c43a495773b549fff4e450780c 208 SUPERFAMILY SSF48498 80 207 2.27E-41 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A6A12_RS08290 21b296c43a495773b549fff4e450780c 208 SUPERFAMILY SSF46689 3 78 1.23E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS08290 21b296c43a495773b549fff4e450780c 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 3.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A6A12_RS08290 21b296c43a495773b549fff4e450780c 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 3.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A6A12_RS08290 21b296c43a495773b549fff4e450780c 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 54 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A6A12_RS08290 21b296c43a495773b549fff4e450780c 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 2.5E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A6A12_RS05525 9e45045a1e854612a855c12568d33f75 367 SUPERFAMILY SSF56104 14 344 3.92E-64 T 28-03-2018 A6A12_RS05525 9e45045a1e854612a855c12568d33f75 367 Pfam PF01259 SAICAR synthetase 22 293 3.3E-45 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A6A12_RS05525 9e45045a1e854612a855c12568d33f75 367 Gene3D G3DSA:3.30.470.20 134 284 7.0E-39 T 28-03-2018 A6A12_RS05525 9e45045a1e854612a855c12568d33f75 367 TIGRFAM TIGR02735 purC_vibrio: phosphoribosylaminoimidazole-succinocarboxamide synthase 2 366 2.0E-216 T 28-03-2018 IPR014106 Phosphoribosylaminoimidazole-succinocarboxamide synthase, Vibrio-type GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A6A12_RS05525 9e45045a1e854612a855c12568d33f75 367 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 19 342 21.436 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A6A12_RS05525 9e45045a1e854612a855c12568d33f75 367 ProSitePatterns PS01057 SAICAR synthetase signature 1. 124 138 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A6A12_RS05525 9e45045a1e854612a855c12568d33f75 367 Gene3D G3DSA:3.30.200.20 9 133 6.9E-28 T 28-03-2018 A6A12_RS12695 39e37c4e440ad10e505aa6fd9ee296b4 197 Pfam PF04350 Pilus assembly protein, PilO 47 189 2.4E-47 T 28-03-2018 IPR007445 Pilus assembly protein, PilO A6A12_RS12695 39e37c4e440ad10e505aa6fd9ee296b4 197 PIRSF PIRSF016482 1 197 4.9E-77 T 28-03-2018 IPR007445 Pilus assembly protein, PilO A6A12_RS12695 39e37c4e440ad10e505aa6fd9ee296b4 197 Gene3D G3DSA:1.10.287.540 57 91 1.4E-8 T 28-03-2018 A6A12_RS12695 39e37c4e440ad10e505aa6fd9ee296b4 197 Gene3D G3DSA:3.30.70.60 92 197 1.8E-22 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A6A12_RS09610 55a4ecd991c0d5fd56656e145a438d7a 405 Gene3D G3DSA:3.30.420.40 84 224 9.0E-30 T 28-03-2018 A6A12_RS09610 55a4ecd991c0d5fd56656e145a438d7a 405 SUPERFAMILY SSF46785 10 77 1.53E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09610 55a4ecd991c0d5fd56656e145a438d7a 405 Pfam PF00480 ROK family 88 390 1.6E-67 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A6A12_RS09610 55a4ecd991c0d5fd56656e145a438d7a 405 Gene3D G3DSA:3.30.420.40 225 375 3.2E-40 T 28-03-2018 A6A12_RS09610 55a4ecd991c0d5fd56656e145a438d7a 405 ProSitePatterns PS01125 ROK family signature. 218 245 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A6A12_RS09610 55a4ecd991c0d5fd56656e145a438d7a 405 SUPERFAMILY SSF53067 86 393 7.21E-56 T 28-03-2018 A6A12_RS09610 55a4ecd991c0d5fd56656e145a438d7a 405 Gene3D G3DSA:1.10.10.10 10 81 1.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03280 6c08dbcb9b4206c82660999301099ab6 99 Gene3D G3DSA:1.10.1270.10 2 99 3.1E-19 T 28-03-2018 A6A12_RS03280 6c08dbcb9b4206c82660999301099ab6 99 Hamap MF_00475 Trp operon repressor [trpR]. 6 99 22.61 T 28-03-2018 IPR013335 Trp repressor, bacterial GO:0006355 A6A12_RS03280 6c08dbcb9b4206c82660999301099ab6 99 Pfam PF01371 Trp repressor protein 9 93 9.6E-31 T 28-03-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 A6A12_RS03280 6c08dbcb9b4206c82660999301099ab6 99 ProDom PD012582 REPRESSOR TRANSCRIPTION TRP OPERON DNA-BINDING REGULATION HOMOLOG AROH FOR TRYPTOPHAN 4 81 3.0E-32 T 28-03-2018 IPR013335 Trp repressor, bacterial GO:0006355 A6A12_RS03280 6c08dbcb9b4206c82660999301099ab6 99 TIGRFAM TIGR01321 TrpR: trp operon repressor 7 88 1.3E-25 T 28-03-2018 IPR013335 Trp repressor, bacterial GO:0006355 A6A12_RS03280 6c08dbcb9b4206c82660999301099ab6 99 SUPERFAMILY SSF48295 3 96 1.88E-28 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A6A12_RS03280 6c08dbcb9b4206c82660999301099ab6 99 PIRSF PIRSF003196 1 99 1.6E-37 T 28-03-2018 IPR013335 Trp repressor, bacterial GO:0006355 A6A12_RS08065 0b950da1de39a9f689f2aae0d2e46cd8 711 SUPERFAMILY SSF52540 462 708 7.89E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS08065 0b950da1de39a9f689f2aae0d2e46cd8 711 Pfam PF00005 ABC transporter 489 638 1.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS08065 0b950da1de39a9f689f2aae0d2e46cd8 711 SUPERFAMILY SSF90123 145 456 1.24E-66 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A6A12_RS08065 0b950da1de39a9f689f2aae0d2e46cd8 711 TIGRFAM TIGR01846 type_I_sec_HlyB: type I secretion system ATPase 20 709 0.0 T 28-03-2018 IPR010132 ATPase, type I secretion system, HlyB GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 A6A12_RS08065 0b950da1de39a9f689f2aae0d2e46cd8 711 Gene3D G3DSA:1.20.1560.10 142 458 2.5E-51 T 28-03-2018 A6A12_RS08065 0b950da1de39a9f689f2aae0d2e46cd8 711 Gene3D G3DSA:3.40.50.300 459 711 1.8E-73 T 28-03-2018 A6A12_RS08065 0b950da1de39a9f689f2aae0d2e46cd8 711 ProSitePatterns PS00211 ABC transporters family signature. 610 624 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS08065 0b950da1de39a9f689f2aae0d2e46cd8 711 Gene3D G3DSA:3.90.70.10 11 126 2.0E-7 T 28-03-2018 A6A12_RS08065 0b950da1de39a9f689f2aae0d2e46cd8 711 Pfam PF00664 ABC transporter transmembrane region 161 427 4.2E-47 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A6A12_RS08065 0b950da1de39a9f689f2aae0d2e46cd8 711 Pfam PF03412 Peptidase C39 family 14 109 6.6E-7 T 28-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 A6A12_RS08065 0b950da1de39a9f689f2aae0d2e46cd8 711 SMART SM00382 498 684 8.8E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS05100 a870eee3de4eba50299e53c7f12f6b91 299 Gene3D G3DSA:3.20.20.330 2 298 1.6E-66 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A6A12_RS05100 a870eee3de4eba50299e53c7f12f6b91 299 PIRSF PIRSF037505 3 296 3.1E-14 T 28-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 A6A12_RS05100 a870eee3de4eba50299e53c7f12f6b91 299 Pfam PF02574 Homocysteine S-methyltransferase 6 291 2.5E-53 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A6A12_RS05100 a870eee3de4eba50299e53c7f12f6b91 299 SUPERFAMILY SSF82282 3 296 4.05E-72 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 A6A12_RS11485 485db1168370b4feb19430b6f6ce3480 132 PRINTS PR00502 NUDIX hydrolase family signature 48 63 3.4E-9 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A6A12_RS11485 485db1168370b4feb19430b6f6ce3480 132 PRINTS PR00502 NUDIX hydrolase family signature 34 48 3.4E-9 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A6A12_RS11485 485db1168370b4feb19430b6f6ce3480 132 SUPERFAMILY SSF55811 1 128 4.47E-33 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A6A12_RS11485 485db1168370b4feb19430b6f6ce3480 132 Gene3D G3DSA:3.90.79.10 1 130 1.7E-27 T 28-03-2018 A6A12_RS11485 485db1168370b4feb19430b6f6ce3480 132 Pfam PF00293 NUDIX domain 6 126 1.0E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A6A12_RS11485 485db1168370b4feb19430b6f6ce3480 132 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A6A12_RS11485 485db1168370b4feb19430b6f6ce3480 132 TIGRFAM TIGR00586 mutt: mutator mutT protein 1 127 1.6E-39 T 28-03-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 A6A12_RS12460 9e3699bb57582ba4f5ee8cf695ded7a0 84 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 6 76 1.1E-37 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12460 9e3699bb57582ba4f5ee8cf695ded7a0 84 SUPERFAMILY SSF50249 6 83 8.14E-34 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS12460 9e3699bb57582ba4f5ee8cf695ded7a0 84 Pfam PF00366 Ribosomal protein S17 10 77 4.1E-34 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12460 9e3699bb57582ba4f5ee8cf695ded7a0 84 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 1 76 3.0E-38 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12460 9e3699bb57582ba4f5ee8cf695ded7a0 84 PRINTS PR00973 Ribosomal protein S17 family signature 24 47 1.1E-14 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12460 9e3699bb57582ba4f5ee8cf695ded7a0 84 PRINTS PR00973 Ribosomal protein S17 family signature 56 66 1.1E-14 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12460 9e3699bb57582ba4f5ee8cf695ded7a0 84 PRINTS PR00973 Ribosomal protein S17 family signature 66 73 1.1E-14 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12460 9e3699bb57582ba4f5ee8cf695ded7a0 84 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 5 80 24.828 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12460 9e3699bb57582ba4f5ee8cf695ded7a0 84 Gene3D G3DSA:2.40.50.140 5 82 1.2E-33 T 28-03-2018 A6A12_RS12460 9e3699bb57582ba4f5ee8cf695ded7a0 84 ProSitePatterns PS00056 Ribosomal protein S17 signature. 56 68 - T 28-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 SMART SM00434 11 498 7.8E-302 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 Gene3D G3DSA:3.90.199.10 285 374 3.2E-9 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 505 4.7E-158 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 817 863 8.6E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 692 709 0.31 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 644 687 5.7E-8 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 767 812 6.5E-13 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 537 583 1.5E-7 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 587 636 8.1E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 735 761 5.8E-7 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 865 24.601 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 Gene3D G3DSA:3.90.199.10 34 284 1.3E-117 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 SUPERFAMILY SSF56719 30 520 3.01E-187 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 Gene3D G3DSA:2.120.10.90 532 880 7.2E-131 T 28-03-2018 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 8 709 0.0 T 28-03-2018 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 Gene3D G3DSA:1.10.268.10 375 496 5.7E-50 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS06195 dc0c5cb91fee3de0d80e7d783943c384 907 SUPERFAMILY SSF101904 532 873 7.98E-106 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A6A12_RS14370 2812316fb67259df6c640b93b357e43e 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 137 4.9E-36 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A6A12_RS14370 2812316fb67259df6c640b93b357e43e 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 13.392 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A6A12_RS14370 2812316fb67259df6c640b93b357e43e 156 Gene3D G3DSA:1.20.5.620 62 122 2.1E-13 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain A6A12_RS14370 2812316fb67259df6c640b93b357e43e 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 156 1.7E-59 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 A6A12_RS14370 2812316fb67259df6c640b93b357e43e 156 SUPERFAMILY SSF81573 63 121 4.71E-14 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain A6A12_RS12670 6346442d3c16da04e7199c81b32f0b53 499 SUPERFAMILY SSF52540 25 191 1.73E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12670 6346442d3c16da04e7199c81b32f0b53 499 Pfam PF05036 Sporulation related domain 412 485 5.2E-7 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A6A12_RS12670 6346442d3c16da04e7199c81b32f0b53 499 Gene3D G3DSA:3.40.50.300 30 187 1.5E-4 T 28-03-2018 A6A12_RS12670 6346442d3c16da04e7199c81b32f0b53 499 Pfam PF13401 AAA domain 31 131 5.4E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS12670 6346442d3c16da04e7199c81b32f0b53 499 Gene3D G3DSA:3.30.70.1070 410 482 0.03 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A6A12_RS12610 e540c39c9e2cc05aeeaa15699e7709bd 403 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 222 259 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A6A12_RS12610 e540c39c9e2cc05aeeaa15699e7709bd 403 SUPERFAMILY SSF53383 16 400 4.98E-127 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS12610 e540c39c9e2cc05aeeaa15699e7709bd 403 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 13 400 45.887 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A6A12_RS12610 e540c39c9e2cc05aeeaa15699e7709bd 403 TIGRFAM TIGR03246 arg_catab_astC: succinylornithine transaminase family 7 402 1.2E-207 T 28-03-2018 IPR017652 Acetyl/Succinylornithine transaminase family, bacteria GO:0006520|GO:0008483|GO:0030170 A6A12_RS12610 e540c39c9e2cc05aeeaa15699e7709bd 403 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 16 399 9.2E-152 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 A6A12_RS12610 e540c39c9e2cc05aeeaa15699e7709bd 403 Pfam PF00202 Aminotransferase class-III 22 399 2.1E-130 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A6A12_RS12610 e540c39c9e2cc05aeeaa15699e7709bd 403 Gene3D G3DSA:3.40.640.10 59 288 3.4E-78 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS12610 e540c39c9e2cc05aeeaa15699e7709bd 403 PIRSF PIRSF000521 171 402 7.5E-37 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A6A12_RS12610 e540c39c9e2cc05aeeaa15699e7709bd 403 PIRSF PIRSF000521 24 157 1.6E-7 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A6A12_RS12610 e540c39c9e2cc05aeeaa15699e7709bd 403 Gene3D G3DSA:3.90.1150.10 289 403 4.7E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS03100 300d8b375015fd3464759ce84fbf9f06 172 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A6A12_RS03100 300d8b375015fd3464759ce84fbf9f06 172 Pfam PF00293 NUDIX domain 7 145 6.7E-26 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A6A12_RS03100 300d8b375015fd3464759ce84fbf9f06 172 Gene3D G3DSA:3.90.79.10 1 164 8.2E-33 T 28-03-2018 A6A12_RS03100 300d8b375015fd3464759ce84fbf9f06 172 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 37.054 T 28-03-2018 IPR022927 RNA pyrophosphohydrolase RppH A6A12_RS03100 300d8b375015fd3464759ce84fbf9f06 172 SUPERFAMILY SSF55811 6 153 3.25E-31 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A6A12_RS03100 300d8b375015fd3464759ce84fbf9f06 172 PRINTS PR00502 NUDIX hydrolase family signature 47 62 8.4E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A6A12_RS03100 300d8b375015fd3464759ce84fbf9f06 172 PRINTS PR00502 NUDIX hydrolase family signature 33 47 8.4E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A6A12_RS01750 17f1f6d5916d612ad794fd4f670f731c 323 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site A6A12_RS01750 17f1f6d5916d612ad794fd4f670f731c 323 Pfam PF00348 Polyprenyl synthetase 32 272 6.1E-77 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 A6A12_RS01750 17f1f6d5916d612ad794fd4f670f731c 323 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site A6A12_RS01750 17f1f6d5916d612ad794fd4f670f731c 323 SUPERFAMILY SSF48576 4 322 1.27E-103 T 28-03-2018 IPR008949 Isoprenoid synthase domain A6A12_RS01750 17f1f6d5916d612ad794fd4f670f731c 323 Gene3D G3DSA:1.10.600.10 1 323 1.8E-104 T 28-03-2018 IPR008949 Isoprenoid synthase domain A6A12_RS05325 a3e9d5bbf239c70de598d19713317d45 175 Pfam PF12915 Protein of unknown function (DUF3833) 14 174 4.8E-65 T 28-03-2018 IPR024409 Protein of unknown function DUF3833 A6A12_RS04540 b7779f0975dc3dc155887be18bd6cfc3 462 Gene3D G3DSA:1.20.1250.20 215 461 4.3E-19 T 28-03-2018 A6A12_RS04540 b7779f0975dc3dc155887be18bd6cfc3 462 Gene3D G3DSA:1.20.1250.20 4 213 5.2E-24 T 28-03-2018 A6A12_RS04540 b7779f0975dc3dc155887be18bd6cfc3 462 SUPERFAMILY SSF103473 8 434 6.54E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain A6A12_RS04540 b7779f0975dc3dc155887be18bd6cfc3 462 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 224 440 3.4E-46 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 A6A12_RS04540 b7779f0975dc3dc155887be18bd6cfc3 462 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 6 214 1.2E-57 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 A6A12_RS04540 b7779f0975dc3dc155887be18bd6cfc3 462 Pfam PF00854 POT family 232 405 1.6E-30 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 A6A12_RS04540 b7779f0975dc3dc155887be18bd6cfc3 462 Pfam PF00854 POT family 85 199 3.1E-29 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 A6A12_RS04540 b7779f0975dc3dc155887be18bd6cfc3 462 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 153 165 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 A6A12_RS10230 82952ab1963f4d1f1e4bf7be046b6e6d 469 SMART SM00448 4 115 6.5E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS10230 82952ab1963f4d1f1e4bf7be046b6e6d 469 Gene3D G3DSA:3.40.50.2300 1 129 1.4E-33 T 28-03-2018 A6A12_RS10230 82952ab1963f4d1f1e4bf7be046b6e6d 469 Pfam PF02954 Bacterial regulatory protein, Fis family 420 459 3.7E-12 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS10230 82952ab1963f4d1f1e4bf7be046b6e6d 469 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 215 230 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A6A12_RS10230 82952ab1963f4d1f1e4bf7be046b6e6d 469 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 342 351 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A6A12_RS10230 82952ab1963f4d1f1e4bf7be046b6e6d 469 SMART SM00382 149 296 6.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS10230 82952ab1963f4d1f1e4bf7be046b6e6d 469 SUPERFAMILY SSF46689 342 460 5.38E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS10230 82952ab1963f4d1f1e4bf7be046b6e6d 469 Gene3D G3DSA:1.10.8.60 302 372 8.0E-25 T 28-03-2018 A6A12_RS10230 82952ab1963f4d1f1e4bf7be046b6e6d 469 Pfam PF00072 Response regulator receiver domain 6 115 2.7E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS10230 82952ab1963f4d1f1e4bf7be046b6e6d 469 SUPERFAMILY SSF52172 3 173 2.99E-40 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS10230 82952ab1963f4d1f1e4bf7be046b6e6d 469 Pfam PF00158 Sigma-54 interaction domain 134 295 1.6E-65 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A6A12_RS10230 82952ab1963f4d1f1e4bf7be046b6e6d 469 Gene3D G3DSA:3.40.50.300 130 300 4.7E-28 T 28-03-2018 A6A12_RS10230 82952ab1963f4d1f1e4bf7be046b6e6d 469 Gene3D G3DSA:1.10.10.60 403 461 1.2E-10 T 28-03-2018 A6A12_RS10230 82952ab1963f4d1f1e4bf7be046b6e6d 469 SUPERFAMILY SSF52540 135 370 3.15E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12930 f730d03029ee6e2da3e47a28712ffc4f 803 SUPERFAMILY SSF51735 448 623 3.94E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS12930 f730d03029ee6e2da3e47a28712ffc4f 803 SUPERFAMILY SSF55347 601 784 3.07E-45 T 28-03-2018 A6A12_RS12930 f730d03029ee6e2da3e47a28712ffc4f 803 Gene3D G3DSA:3.40.1160.10 4 306 3.2E-47 T 28-03-2018 A6A12_RS12930 f730d03029ee6e2da3e47a28712ffc4f 803 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 8 445 5.7E-63 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS12930 f730d03029ee6e2da3e47a28712ffc4f 803 PIRSF PIRSF000727 5 803 2.0E-285 T 28-03-2018 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+2.7.2.4+1.1.1.3|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4+1.1.1.3|KEGG: 00300+2.7.2.4+1.1.1.3|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS12930 f730d03029ee6e2da3e47a28712ffc4f 803 Pfam PF00742 Homoserine dehydrogenase 601 796 6.3E-43 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A6A12_RS12930 f730d03029ee6e2da3e47a28712ffc4f 803 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 647 669 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A6A12_RS12930 f730d03029ee6e2da3e47a28712ffc4f 803 ProSitePatterns PS00324 Aspartokinase signature. 7 15 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS12930 f730d03029ee6e2da3e47a28712ffc4f 803 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 457 593 1.1E-15 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A6A12_RS12930 f730d03029ee6e2da3e47a28712ffc4f 803 SUPERFAMILY SSF53633 6 291 6.02E-60 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS12930 f730d03029ee6e2da3e47a28712ffc4f 803 Gene3D G3DSA:3.40.50.720 447 622 1.0E-24 T 28-03-2018 A6A12_RS12930 f730d03029ee6e2da3e47a28712ffc4f 803 Pfam PF00696 Amino acid kinase family 6 277 1.6E-43 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS12930 f730d03029ee6e2da3e47a28712ffc4f 803 Gene3D G3DSA:3.30.360.10 623 780 3.0E-51 T 28-03-2018 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 SUPERFAMILY SSF54980 401 478 3.2E-20 T 28-03-2018 IPR035647 EF-G domain III/V-like A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 Gene3D G3DSA:3.30.70.240 611 688 1.4E-28 T 28-03-2018 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 Gene3D G3DSA:3.30.230.10 489 610 1.2E-38 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 SMART SM00889 477 595 5.2E-62 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 176 3.8E-25 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 SMART SM00838 597 684 1.9E-46 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.2E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 PRINTS PR00315 GTP-binding elongation factor signature 127 136 1.2E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 PRINTS PR00315 GTP-binding elongation factor signature 75 85 1.2E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 PRINTS PR00315 GTP-binding elongation factor signature 55 63 1.2E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 Gene3D G3DSA:3.30.70.870 393 488 7.8E-30 T 28-03-2018 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 Pfam PF03764 Elongation factor G, domain IV 476 594 2.2E-44 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 Pfam PF14492 Elongation Factor G, domain II 401 474 3.4E-27 T 28-03-2018 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 SUPERFAMILY SSF54211 476 595 3.03E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 SUPERFAMILY SSF54980 600 692 3.6E-29 T 28-03-2018 IPR035647 EF-G domain III/V-like A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 Pfam PF00679 Elongation factor G C-terminus 597 683 6.8E-28 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 Gene3D G3DSA:2.40.30.10 271 392 1.2E-30 T 28-03-2018 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 SUPERFAMILY SSF50447 261 399 4.2E-33 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 Hamap MF_00054_B Elongation factor G [fusA]. 3 688 101.082 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 Pfam PF03144 Elongation factor Tu domain 2 321 388 5.4E-17 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 TIGRFAM TIGR00484 EF-G: translation elongation factor G 3 688 4.5E-293 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 Gene3D G3DSA:3.40.50.300 1 270 2.2E-54 T 28-03-2018 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 Pfam PF00009 Elongation factor Tu GTP binding domain 6 277 6.2E-60 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS11275 f1aaec3130fe251ac47ad743401f25f6 697 SUPERFAMILY SSF52540 3 277 2.44E-100 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01180 f926d4753ee5afa5e26a34607f270e6e 121 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 4 48 2.7E-16 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01180 f926d4753ee5afa5e26a34607f270e6e 121 Gene3D G3DSA:1.20.5.710 2 50 9.0E-15 T 28-03-2018 A6A12_RS01180 f926d4753ee5afa5e26a34607f270e6e 121 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 55 121 8.8E-30 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01180 f926d4753ee5afa5e26a34607f270e6e 121 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 121 1.4E-45 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01180 f926d4753ee5afa5e26a34607f270e6e 121 SUPERFAMILY SSF54736 50 121 4.53E-24 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A6A12_RS01180 f926d4753ee5afa5e26a34607f270e6e 121 SUPERFAMILY SSF48300 4 57 1.2E-15 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01180 f926d4753ee5afa5e26a34607f270e6e 121 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 57 121 1.0E-15 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01180 f926d4753ee5afa5e26a34607f270e6e 121 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 121 24.537 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01180 f926d4753ee5afa5e26a34607f270e6e 121 Gene3D G3DSA:3.30.1390.10 51 121 3.0E-29 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A6A12_RS08850 7c3e7a50aabef00be60da4ab8d54994d 460 Gene3D G3DSA:1.20.120.640 306 392 4.7E-20 T 28-03-2018 A6A12_RS08850 7c3e7a50aabef00be60da4ab8d54994d 460 SMART SM00840 341 402 3.3E-25 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A6A12_RS08850 7c3e7a50aabef00be60da4ab8d54994d 460 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 460 38.942 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A6A12_RS08850 7c3e7a50aabef00be60da4ab8d54994d 460 SUPERFAMILY SSF52374 1 313 3.22E-103 T 28-03-2018 A6A12_RS08850 7c3e7a50aabef00be60da4ab8d54994d 460 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 459 1.8E-191 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A6A12_RS08850 7c3e7a50aabef00be60da4ab8d54994d 460 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 313 5.6E-142 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A6A12_RS08850 7c3e7a50aabef00be60da4ab8d54994d 460 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 2.7E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A6A12_RS08850 7c3e7a50aabef00be60da4ab8d54994d 460 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 2.7E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A6A12_RS08850 7c3e7a50aabef00be60da4ab8d54994d 460 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 2.7E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A6A12_RS08850 7c3e7a50aabef00be60da4ab8d54994d 460 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 2.7E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A6A12_RS08850 7c3e7a50aabef00be60da4ab8d54994d 460 Pfam PF09190 DALR domain 341 402 1.4E-23 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A6A12_RS08850 7c3e7a50aabef00be60da4ab8d54994d 460 SUPERFAMILY SSF47323 316 459 1.03E-38 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS08850 7c3e7a50aabef00be60da4ab8d54994d 460 Gene3D G3DSA:3.40.50.620 1 305 3.5E-96 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS01005 1e5d97f9595b5e235814eabc2579485b 463 TIGRFAM TIGR03173 pbuX: xanthine permease 29 448 3.9E-131 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 A6A12_RS01005 1e5d97f9595b5e235814eabc2579485b 463 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 364 384 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A6A12_RS01005 1e5d97f9595b5e235814eabc2579485b 463 Pfam PF00860 Permease family 24 416 2.4E-99 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A6A12_RS01005 1e5d97f9595b5e235814eabc2579485b 463 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 19 446 4.2E-126 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A6A12_RS07260 45aab7894fbabdf96b9567b064e8abd8 364 Gene3D G3DSA:3.90.10.10 36 357 7.9E-30 T 28-03-2018 A6A12_RS07260 45aab7894fbabdf96b9567b064e8abd8 364 SUPERFAMILY SSF48695 12 179 5.92E-48 T 28-03-2018 IPR011031 Multihaem cytochrome A6A12_RS07260 45aab7894fbabdf96b9567b064e8abd8 364 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 4 174 1.1E-66 T 28-03-2018 IPR005126 NapC/NirT cytochrome c, N-terminal A6A12_RS07260 45aab7894fbabdf96b9567b064e8abd8 364 PIRSF PIRSF000014 1 364 1.7E-145 T 28-03-2018 IPR009154 Membrane-bound tetrahaem cytochrome TorC/YecK GO:0005506|GO:0009055|GO:0009276|GO:0016021|GO:0020037 A6A12_RS08210 2eafb2dc4cc5850aae83e8c87817e31f 114 SMART SM01022 7 105 4.5E-26 T 28-03-2018 IPR007374 ASCH domain A6A12_RS08210 2eafb2dc4cc5850aae83e8c87817e31f 114 SUPERFAMILY SSF88697 4 104 8.95E-31 T 28-03-2018 IPR015947 PUA-like domain A6A12_RS08210 2eafb2dc4cc5850aae83e8c87817e31f 114 Pfam PF04266 ASCH domain 7 104 1.7E-13 T 28-03-2018 IPR007374 ASCH domain A6A12_RS08210 2eafb2dc4cc5850aae83e8c87817e31f 114 Gene3D G3DSA:2.30.130.30 2 104 5.7E-17 T 28-03-2018 A6A12_RS08210 2eafb2dc4cc5850aae83e8c87817e31f 114 Hamap MF_00684 UPF0267 protein YqfB [yqfB]. 3 104 29.82 T 28-03-2018 IPR008314 Uncharacterised conserved protein UCP029143 A6A12_RS08210 2eafb2dc4cc5850aae83e8c87817e31f 114 PIRSF PIRSF029143 2 106 1.8E-44 T 28-03-2018 IPR008314 Uncharacterised conserved protein UCP029143 A6A12_RS09205 5310c9b9adcecbe4cc4ac9fdfcad3040 323 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS09205 5310c9b9adcecbe4cc4ac9fdfcad3040 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 296 2.5E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A6A12_RS09205 5310c9b9adcecbe4cc4ac9fdfcad3040 323 SUPERFAMILY SSF52540 32 301 1.66E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09205 5310c9b9adcecbe4cc4ac9fdfcad3040 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 315 2.4E-24 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A6A12_RS09205 5310c9b9adcecbe4cc4ac9fdfcad3040 323 Gene3D G3DSA:3.40.50.300 1 321 1.6E-72 T 28-03-2018 A6A12_RS09205 5310c9b9adcecbe4cc4ac9fdfcad3040 323 Pfam PF00005 ABC transporter 24 180 6.8E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS09205 5310c9b9adcecbe4cc4ac9fdfcad3040 323 SMART SM00382 32 238 8.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS00865 9c45c32814486fd9cf6d3bb7e196ab4c 499 Gene3D G3DSA:3.30.450.90 87 224 8.1E-49 T 28-03-2018 A6A12_RS00865 9c45c32814486fd9cf6d3bb7e196ab4c 499 SUPERFAMILY SSF52540 106 496 2.47E-107 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS00865 9c45c32814486fd9cf6d3bb7e196ab4c 499 Gene3D G3DSA:3.40.50.300 225 499 3.2E-68 T 28-03-2018 A6A12_RS00865 9c45c32814486fd9cf6d3bb7e196ab4c 499 SUPERFAMILY SSF160246 11 77 2.41E-14 T 28-03-2018 A6A12_RS00865 9c45c32814486fd9cf6d3bb7e196ab4c 499 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 11 496 1.2E-230 T 28-03-2018 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 A6A12_RS00865 9c45c32814486fd9cf6d3bb7e196ab4c 499 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 319 333 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A6A12_RS00865 9c45c32814486fd9cf6d3bb7e196ab4c 499 SMART SM00382 252 375 5.8E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS00865 9c45c32814486fd9cf6d3bb7e196ab4c 499 Pfam PF00437 Type II/IV secretion system protein 126 391 2.4E-91 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A6A12_RS11055 ef668ba3e8ed7693cd74de44bb8caa7a 198 PIRSF PIRSF006102 1 198 7.6E-67 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 A6A12_RS11055 ef668ba3e8ed7693cd74de44bb8caa7a 198 TIGRFAM TIGR01940 nqrE: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit 2 197 3.0E-106 T 28-03-2018 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 A6A12_RS11055 ef668ba3e8ed7693cd74de44bb8caa7a 198 Hamap MF_00429 Na(+)-translocating NADH-quinone reductase subunit E [nqrE]. 1 198 29.882 T 28-03-2018 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 A6A12_RS11055 ef668ba3e8ed7693cd74de44bb8caa7a 198 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 196 1.4E-60 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 A6A12_RS01385 c726ed2ea739cec23b8097ba2575200f 100 Gene3D G3DSA:2.40.50.140 1 100 2.7E-11 T 28-03-2018 A6A12_RS01385 c726ed2ea739cec23b8097ba2575200f 100 SUPERFAMILY SSF50249 1 99 2.09E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS01385 c726ed2ea739cec23b8097ba2575200f 100 Pfam PF00436 Single-strand binding protein family 3 89 2.8E-9 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 A6A12_RS01385 c726ed2ea739cec23b8097ba2575200f 100 PIRSF PIRSF003135 1 100 3.3E-45 T 28-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 A6A12_RS01385 c726ed2ea739cec23b8097ba2575200f 100 TIGRFAM TIGR04418 PriB_gamma: primosomal replication protein PriB 3 100 1.8E-32 T 28-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 A6A12_RS01385 c726ed2ea739cec23b8097ba2575200f 100 Hamap MF_00720 Primosomal replication protein N [priB]. 2 100 22.739 T 28-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 252 278 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 281 1.6E-35 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 Pfam PF04545 Sigma-70, region 4 229 279 1.0E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 Gene3D G3DSA:1.10.10.10 141 182 0.11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 2 284 53.928 T 28-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 77 90 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 PRINTS PR00046 Major sigma-70 factor signature 267 278 3.4E-19 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 PRINTS PR00046 Major sigma-70 factor signature 233 245 3.4E-19 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 PRINTS PR00046 Major sigma-70 factor signature 252 267 3.4E-19 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 PRINTS PR00046 Major sigma-70 factor signature 77 90 3.4E-19 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 15 282 8.6E-127 T 28-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 Pfam PF04542 Sigma-70 region 2 53 122 6.4E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 SUPERFAMILY SSF88659 198 282 1.51E-19 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 PIRSF PIRSF000770 4 284 5.6E-33 T 28-03-2018 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 SUPERFAMILY SSF88946 11 122 1.43E-39 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 Gene3D G3DSA:1.10.601.10 3 122 2.2E-34 T 28-03-2018 A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 Gene3D G3DSA:1.10.10.10 223 284 7.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS00555 fd5bc50f19820e96bcdf9197b592c93f 285 Pfam PF00140 Sigma-70 factor, region 1.2 14 40 5.0E-8 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS11160 3972560ac9ec5f0e58a9761067f059ec 456 SUPERFAMILY SSF55729 311 435 9.92E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS11160 3972560ac9ec5f0e58a9761067f059ec 456 Gene3D G3DSA:3.40.630.30 311 455 8.3E-19 T 28-03-2018 A6A12_RS11160 3972560ac9ec5f0e58a9761067f059ec 456 PIRSF PIRSF000423 9 456 3.8E-205 T 28-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 A6A12_RS11160 3972560ac9ec5f0e58a9761067f059ec 456 Gene3D G3DSA:3.40.1160.10 17 308 7.3E-57 T 28-03-2018 A6A12_RS11160 3972560ac9ec5f0e58a9761067f059ec 456 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 456 220.245 T 28-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 A6A12_RS11160 3972560ac9ec5f0e58a9761067f059ec 456 Pfam PF00583 Acetyltransferase (GNAT) family 345 428 2.7E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A6A12_RS11160 3972560ac9ec5f0e58a9761067f059ec 456 Pfam PF00696 Amino acid kinase family 36 281 2.9E-30 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS11160 3972560ac9ec5f0e58a9761067f059ec 456 SUPERFAMILY SSF53633 14 305 4.47E-68 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS11160 3972560ac9ec5f0e58a9761067f059ec 456 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 19 456 3.9E-214 T 28-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 A6A12_RS04485 c225ea7d9466ff4d477b715db7cdcf71 155 Pfam PF01957 NfeD-like C-terminal, partner-binding 12 150 1.7E-22 T 28-03-2018 IPR002810 NfeD-like, C-terminal domain A6A12_RS04485 c225ea7d9466ff4d477b715db7cdcf71 155 Gene3D G3DSA:2.40.50.140 80 155 5.8E-14 T 28-03-2018 A6A12_RS01200 b3768fb350b7b5458af392fd89c7e27f 308 Pfam PF00293 NUDIX domain 180 279 6.8E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A6A12_RS01200 b3768fb350b7b5458af392fd89c7e27f 308 SUPERFAMILY SSF55811 127 291 2.03E-40 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A6A12_RS01200 b3768fb350b7b5458af392fd89c7e27f 308 Gene3D G3DSA:3.90.79.10 174 305 9.8E-34 T 28-03-2018 A6A12_RS01200 b3768fb350b7b5458af392fd89c7e27f 308 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 144 172 2.3E-9 T 28-03-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 A6A12_RS01200 b3768fb350b7b5458af392fd89c7e27f 308 Hamap MF_00297 NADH pyrophosphatase [nudC]. 46 305 41.612 T 28-03-2018 IPR022925 NADH pyrophosphatase NudC GO:0000210 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 A6A12_RS01200 b3768fb350b7b5458af392fd89c7e27f 308 ProSitePatterns PS00893 Nudix box signature. 207 228 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A6A12_RS01200 b3768fb350b7b5458af392fd89c7e27f 308 SUPERFAMILY SSF55811 52 144 1.3E-21 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A6A12_RS01990 aa931f1c91850c95d05f55f1b5846911 341 SMART SM00846 2 159 3.3E-71 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01990 aa931f1c91850c95d05f55f1b5846911 341 PIRSF PIRSF000149 1 341 2.7E-126 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01990 aa931f1c91850c95d05f55f1b5846911 341 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 180 196 2.1E-31 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01990 aa931f1c91850c95d05f55f1b5846911 341 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 236 253 2.1E-31 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01990 aa931f1c91850c95d05f55f1b5846911 341 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 153 171 2.1E-31 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01990 aa931f1c91850c95d05f55f1b5846911 341 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 116 129 2.1E-31 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01990 aa931f1c91850c95d05f55f1b5846911 341 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 276 291 2.1E-31 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01990 aa931f1c91850c95d05f55f1b5846911 341 TIGRFAM TIGR01532 E4PD_g-proteo: erythrose-4-phosphate dehydrogenase 3 332 4.2E-191 T 28-03-2018 IPR006422 D-erythrose-4-phosphate dehydrogenase GO:0005737|GO:0042823|GO:0048001|GO:0051287|GO:0055114 KEGG: 00750+1.2.1.72 A6A12_RS01990 aa931f1c91850c95d05f55f1b5846911 341 Gene3D G3DSA:3.30.360.10 169 322 2.1E-51 T 28-03-2018 A6A12_RS01990 aa931f1c91850c95d05f55f1b5846911 341 Gene3D G3DSA:3.40.50.720 1 168 9.8E-63 T 28-03-2018 A6A12_RS01990 aa931f1c91850c95d05f55f1b5846911 341 Hamap MF_01640 D-erythrose-4-phosphate dehydrogenase [epd]. 1 341 65.518 T 28-03-2018 IPR006422 D-erythrose-4-phosphate dehydrogenase GO:0005737|GO:0042823|GO:0048001|GO:0051287|GO:0055114 KEGG: 00750+1.2.1.72 A6A12_RS01990 aa931f1c91850c95d05f55f1b5846911 341 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 164 320 3.3E-55 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01990 aa931f1c91850c95d05f55f1b5846911 341 SUPERFAMILY SSF55347 159 321 4.17E-58 T 28-03-2018 A6A12_RS01990 aa931f1c91850c95d05f55f1b5846911 341 SUPERFAMILY SSF51735 2 185 1.5E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS01990 aa931f1c91850c95d05f55f1b5846911 341 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 109 5.1E-31 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 788 46.648 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 Pfam PF01588 Putative tRNA binding domain 45 145 3.6E-26 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 Gene3D G3DSA:2.40.50.140 54 141 5.8E-41 T 28-03-2018 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 Pfam PF03483 B3/4 domain 212 385 3.1E-69 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 SUPERFAMILY SSF55681 467 688 1.39E-52 T 28-03-2018 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 Gene3D G3DSA:3.30.56.10 1 53 2.9E-12 T 28-03-2018 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 SUPERFAMILY SSF56037 197 394 3.92E-75 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 SMART SM00874 403 471 7.3E-30 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 794 1.2E-277 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 SUPERFAMILY SSF54991 697 794 1.22E-29 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 SUPERFAMILY SSF46955 403 475 7.32E-20 T 28-03-2018 IPR009061 Putative DNA-binding domain A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 Gene3D G3DSA:3.30.930.10 489 690 1.5E-37 T 28-03-2018 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 Gene3D G3DSA:3.50.40.10 195 394 4.0E-72 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 Pfam PF03484 tRNA synthetase B5 domain 406 471 4.8E-18 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 SMART SM00896 701 794 1.9E-44 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 Gene3D G3DSA:3.30.70.380 698 794 8.6E-25 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 SUPERFAMILY SSF50249 39 197 6.37E-48 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 Gene3D G3DSA:3.30.56.10 142 183 0.05 T 28-03-2018 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 SMART SM00873 212 385 1.2E-96 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 Gene3D G3DSA:3.30.56.10 402 475 2.5E-24 T 28-03-2018 A6A12_RS08135 34cdba9eb19947582b5d749842e0c30c 795 Pfam PF03147 Ferredoxin-fold anticodon binding domain 701 794 1.8E-28 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 A6A12_RS12140 a04aa77608401387c53c497952d4fd35 184 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 22 173 6.3E-61 T 28-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A6A12_RS12140 a04aa77608401387c53c497952d4fd35 184 Gene3D G3DSA:3.40.50.1000 3 184 7.5E-27 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS12140 a04aa77608401387c53c497952d4fd35 184 PIRSF PIRSF006118 10 184 7.4E-73 T 28-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A6A12_RS12140 a04aa77608401387c53c497952d4fd35 184 Pfam PF08282 haloacid dehalogenase-like hydrolase 92 156 3.7E-9 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS12140 a04aa77608401387c53c497952d4fd35 184 SUPERFAMILY SSF56784 20 177 4.94E-41 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS12140 a04aa77608401387c53c497952d4fd35 184 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 23 136 2.4E-12 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A6A12_RS01245 b2a7cdd4824c7ae7c13536007b78346e 285 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 9 285 48.175 T 28-03-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 A6A12_RS01245 b2a7cdd4824c7ae7c13536007b78346e 285 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 48 283 8.6E-84 T 28-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 A6A12_RS01245 b2a7cdd4824c7ae7c13536007b78346e 285 Pfam PF02666 Phosphatidylserine decarboxylase 62 279 3.6E-59 T 28-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 A6A12_RS06535 6a9210eb74a2cd406221b8fc06b16bf7 160 SUPERFAMILY SSF89963 2 86 2.62E-31 T 28-03-2018 IPR007551 Protein of unknown function DUF520 A6A12_RS06535 6a9210eb74a2cd406221b8fc06b16bf7 160 Gene3D G3DSA:3.30.70.860 95 159 4.4E-31 T 28-03-2018 IPR035571 UPF0234/UPF0381 domain A6A12_RS06535 6a9210eb74a2cd406221b8fc06b16bf7 160 SUPERFAMILY SSF89963 88 160 3.53E-27 T 28-03-2018 IPR007551 Protein of unknown function DUF520 A6A12_RS06535 6a9210eb74a2cd406221b8fc06b16bf7 160 Gene3D G3DSA:3.30.70.990 10 94 1.0E-29 T 28-03-2018 IPR035570 UPF0234 N-terminal domain A6A12_RS06535 6a9210eb74a2cd406221b8fc06b16bf7 160 Pfam PF04461 Protein of unknown function (DUF520) 2 159 1.4E-62 T 28-03-2018 IPR007551 Protein of unknown function DUF520 A6A12_RS06535 6a9210eb74a2cd406221b8fc06b16bf7 160 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 160 29.208 T 28-03-2018 IPR007551 Protein of unknown function DUF520 A6A12_RS04915 ec47c9ba4492d75e6c9f0daa8fee3cab 109 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 98 23.486 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A6A12_RS04915 ec47c9ba4492d75e6c9f0daa8fee3cab 109 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 105 1.1E-39 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A6A12_RS04915 ec47c9ba4492d75e6c9f0daa8fee3cab 109 SUPERFAMILY SSF82607 11 103 1.12E-36 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A6A12_RS04915 ec47c9ba4492d75e6c9f0daa8fee3cab 109 Gene3D G3DSA:3.30.1310.10 1 109 5.3E-46 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A6A12_RS04915 ec47c9ba4492d75e6c9f0daa8fee3cab 109 Pfam PF02575 YbaB/EbfC DNA-binding family 11 100 5.8E-35 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A6A12_RS04915 ec47c9ba4492d75e6c9f0daa8fee3cab 109 PIRSF PIRSF004555 3 109 7.2E-40 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family A6A12_RS14135 f72db52d9bec8c7b677d526182aecfab 570 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 299 509 1.5E-34 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A6A12_RS14135 f72db52d9bec8c7b677d526182aecfab 570 TIGRFAM TIGR01234 L-ribulokinase: ribulokinase 12 556 3.8E-190 T 28-03-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 A6A12_RS14135 f72db52d9bec8c7b677d526182aecfab 570 Gene3D G3DSA:3.30.420.40 291 568 6.5E-51 T 28-03-2018 A6A12_RS14135 f72db52d9bec8c7b677d526182aecfab 570 SUPERFAMILY SSF53067 12 292 6.09E-29 T 28-03-2018 A6A12_RS14135 f72db52d9bec8c7b677d526182aecfab 570 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 12 289 4.7E-18 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A6A12_RS14135 f72db52d9bec8c7b677d526182aecfab 570 Hamap MF_00520 Ribulokinase [araB]. 10 566 45.363 T 28-03-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 A6A12_RS14135 f72db52d9bec8c7b677d526182aecfab 570 Gene3D G3DSA:3.30.420.40 6 281 2.6E-45 T 28-03-2018 A6A12_RS14135 f72db52d9bec8c7b677d526182aecfab 570 PIRSF PIRSF000538 10 561 2.0E-49 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A6A12_RS14135 f72db52d9bec8c7b677d526182aecfab 570 SUPERFAMILY SSF53067 294 555 1.02E-44 T 28-03-2018 A6A12_RS10490 911b42bcf872710fbadd5b58f295e88d 158 Gene3D G3DSA:3.90.960.10 1 158 8.4E-42 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A6A12_RS10490 911b42bcf872710fbadd5b58f295e88d 158 PIRSF PIRSF006181 1 158 2.1E-53 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC A6A12_RS10490 911b42bcf872710fbadd5b58f295e88d 158 SUPERFAMILY SSF55826 2 156 5.89E-43 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A6A12_RS10490 911b42bcf872710fbadd5b58f295e88d 158 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 2 156 2.3E-58 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC A6A12_RS10490 911b42bcf872710fbadd5b58f295e88d 158 Pfam PF04073 Aminoacyl-tRNA editing domain 32 144 1.5E-24 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A6A12_RS06525 36ea03a05df123d8d0c826581df5ed32 306 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 197 4.8E-62 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A6A12_RS06525 36ea03a05df123d8d0c826581df5ed32 306 Gene3D G3DSA:3.40.1010.10 217 293 0.0021 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A6A12_RS06525 36ea03a05df123d8d0c826581df5ed32 306 Gene3D G3DSA:1.10.8.210 152 207 5.8E-13 T 28-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A6A12_RS06525 36ea03a05df123d8d0c826581df5ed32 306 SUPERFAMILY SSF75615 115 199 8.89E-24 T 28-03-2018 A6A12_RS06525 36ea03a05df123d8d0c826581df5ed32 306 Gene3D G3DSA:3.30.160.110 122 149 3.6E-15 T 28-03-2018 A6A12_RS06525 36ea03a05df123d8d0c826581df5ed32 306 Gene3D G3DSA:3.40.50.720 3 121 9.8E-23 T 28-03-2018 A6A12_RS06525 36ea03a05df123d8d0c826581df5ed32 306 Pfam PF14824 Sirohaem biosynthesis protein central 120 146 1.9E-8 T 28-03-2018 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A6A12_RS06525 36ea03a05df123d8d0c826581df5ed32 306 Pfam PF10414 Sirohaem synthase dimerisation region 151 206 4.7E-13 T 28-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A6A12_RS06525 36ea03a05df123d8d0c826581df5ed32 306 Pfam PF13241 Putative NAD(P)-binding 6 116 8.7E-29 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A6A12_RS06525 36ea03a05df123d8d0c826581df5ed32 306 SUPERFAMILY SSF51735 1 113 2.84E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS06525 36ea03a05df123d8d0c826581df5ed32 306 SUPERFAMILY SSF53790 223 282 4.22E-5 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A6A12_RS10980 f423a3e6bf452840a7579e7be21719e1 135 Pfam PF07417 Transcriptional regulator Crl 12 129 2.4E-49 T 28-03-2018 IPR009986 Sigma factor-binding protein Crl GO:0005737|GO:0045893 A6A12_RS10980 f423a3e6bf452840a7579e7be21719e1 135 Hamap MF_01178 Sigma factor-binding protein Crl [crl]. 8 135 30.623 T 28-03-2018 IPR009986 Sigma factor-binding protein Crl GO:0005737|GO:0045893 A6A12_RS01595 b8e78bb28bc634356d5bbe4b2349a73b 290 Gene3D G3DSA:3.40.50.300 34 198 3.8E-12 T 28-03-2018 A6A12_RS01595 b8e78bb28bc634356d5bbe4b2349a73b 290 SUPERFAMILY SSF52540 15 269 4.79E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01595 b8e78bb28bc634356d5bbe4b2349a73b 290 Pfam PF13401 AAA domain 51 177 1.1E-23 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1062 13.081 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 709 723 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 SUPERFAMILY SSF52440 556 675 2.01E-49 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 SUPERFAMILY SSF56059 128 401 3.71E-108 T 28-03-2018 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1067 13.369 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 SUPERFAMILY SSF48108 396 554 3.92E-51 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 427 547 2.0E-39 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 Pfam PF02142 MGS-like domain 956 1041 1.1E-16 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 838 845 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 Gene3D G3DSA:1.10.1030.10 404 538 5.6E-51 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 SUPERFAMILY SSF56059 673 932 7.6E-104 T 28-03-2018 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 Gene3D G3DSA:3.30.470.20 119 403 5.0E-64 T 28-03-2018 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 SMART SM01096 424 547 4.6E-73 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 Gene3D G3DSA:3.40.50.20 539 654 3.0E-61 T 28-03-2018 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1050 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 Gene3D G3DSA:3.30.1490.20 655 744 8.4E-23 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 SUPERFAMILY SSF52335 936 1071 2.22E-35 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 SUPERFAMILY SSF52440 1 127 1.73E-50 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 Gene3D G3DSA:3.30.470.20 745 935 5.8E-44 T 28-03-2018 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 Gene3D G3DSA:3.40.50.20 4 109 5.4E-40 T 28-03-2018 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 673 874 1.8E-37 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 2.3E-72 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 Gene3D G3DSA:3.40.50.1380 937 1072 3.0E-27 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 1.6E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.6E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 1.6E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.6E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.6E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.6E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.6E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11470 30995a950da14298f699f3a35fbaf5c4 1076 SMART SM00851 955 1041 1.2E-27 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A6A12_RS03460 5fdd65d038e2c4bf1460245be39159f6 350 SUPERFAMILY SSF111337 1 345 5.49E-140 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A6A12_RS03460 5fdd65d038e2c4bf1460245be39159f6 350 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 346 2.7E-157 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A6A12_RS03460 5fdd65d038e2c4bf1460245be39159f6 350 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 346 47.374 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A6A12_RS03460 5fdd65d038e2c4bf1460245be39159f6 350 Pfam PF02547 Queuosine biosynthesis protein 3 345 2.1E-134 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 A6A12_RS03460 5fdd65d038e2c4bf1460245be39159f6 350 Gene3D G3DSA:3.40.1780.10 1 142 3.8E-30 T 28-03-2018 A6A12_RS03460 5fdd65d038e2c4bf1460245be39159f6 350 Gene3D G3DSA:3.40.1780.10 175 346 5.5E-67 T 28-03-2018 A6A12_RS08020 e1c791e2b7f9a3c697c9357a3d921de0 200 SUPERFAMILY SSF53254 3 181 1.43E-33 T 28-03-2018 IPR029033 Histidine phosphatase superfamily A6A12_RS08020 e1c791e2b7f9a3c697c9357a3d921de0 200 PIRSF PIRSF000709 8 193 0.0059 T 28-03-2018 A6A12_RS08020 e1c791e2b7f9a3c697c9357a3d921de0 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 191 3.9E-30 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A6A12_RS08020 e1c791e2b7f9a3c697c9357a3d921de0 200 SMART SM00855 3 153 7.6E-12 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A6A12_RS08020 e1c791e2b7f9a3c697c9357a3d921de0 200 Gene3D G3DSA:3.40.50.1240 1 198 7.4E-35 T 28-03-2018 IPR029033 Histidine phosphatase superfamily A6A12_RS07065 22644120d93ff929af79a67622186e1f 621 SMART SM00857 11 171 2.0E-16 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A6A12_RS07065 22644120d93ff929af79a67622186e1f 621 Gene3D G3DSA:3.40.50.1390 6 171 2.6E-21 T 28-03-2018 A6A12_RS07065 22644120d93ff929af79a67622186e1f 621 Pfam PF07508 Recombinase 211 301 1.3E-11 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 A6A12_RS07065 22644120d93ff929af79a67622186e1f 621 SUPERFAMILY SSF53041 11 165 1.7E-10 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A6A12_RS07065 22644120d93ff929af79a67622186e1f 621 Pfam PF00239 Resolvase, N terminal domain 11 166 9.7E-15 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A6A12_RS04745 9a596331ce4764e1ea8a56d66ca715fb 676 SUPERFAMILY SSF52540 3 416 1.48E-138 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS04745 9a596331ce4764e1ea8a56d66ca715fb 676 Pfam PF02151 UvrB/uvrC motif 636 671 7.8E-8 T 28-03-2018 IPR001943 UVR domain GO:0005515 A6A12_RS04745 9a596331ce4764e1ea8a56d66ca715fb 676 Gene3D G3DSA:3.40.50.300 416 590 6.7E-32 T 28-03-2018 A6A12_RS04745 9a596331ce4764e1ea8a56d66ca715fb 676 Pfam PF00271 Helicase conserved C-terminal domain 439 545 6.2E-18 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS04745 9a596331ce4764e1ea8a56d66ca715fb 676 Gene3D G3DSA:3.40.50.300 11 415 3.4E-33 T 28-03-2018 A6A12_RS04745 9a596331ce4764e1ea8a56d66ca715fb 676 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 671 42.968 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 A6A12_RS04745 9a596331ce4764e1ea8a56d66ca715fb 676 Gene3D G3DSA:4.10.860.10 616 676 7.6E-17 T 28-03-2018 IPR001943 UVR domain GO:0005515 A6A12_RS04745 9a596331ce4764e1ea8a56d66ca715fb 676 SMART SM00487 9 426 3.0E-27 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS04745 9a596331ce4764e1ea8a56d66ca715fb 676 SUPERFAMILY SSF52540 460 575 1.81E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS04745 9a596331ce4764e1ea8a56d66ca715fb 676 SUPERFAMILY SSF52540 37 82 1.81E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS04745 9a596331ce4764e1ea8a56d66ca715fb 676 SUPERFAMILY SSF46600 625 672 3.79E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 A6A12_RS04745 9a596331ce4764e1ea8a56d66ca715fb 676 SMART SM00490 461 547 2.6E-20 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS04745 9a596331ce4764e1ea8a56d66ca715fb 676 Pfam PF12344 Ultra-violet resistance protein B 553 594 2.4E-20 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain A6A12_RS04745 9a596331ce4764e1ea8a56d66ca715fb 676 Pfam PF04851 Type III restriction enzyme, res subunit 16 138 8.5E-9 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A6A12_RS04745 9a596331ce4764e1ea8a56d66ca715fb 676 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 4 669 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 Gene3D G3DSA:2.60.220.10 271 419 0.56 T 28-03-2018 A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 Gene3D G3DSA:2.60.220.10 137 266 1.9E-30 T 28-03-2018 A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1364 1380 0.01 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1328 1344 0.027 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1251 1267 0.064 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1345 1361 22.0 T 28-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 188 284 3.3E-32 T 28-03-2018 IPR010221 VCBS repeat A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 1116 1179 1.1E-4 T 28-03-2018 IPR010221 VCBS repeat A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 SUPERFAMILY SSF51120 1316 1446 6.41E-21 T 28-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 1399 1489 1.2E-5 T 28-03-2018 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 PRINTS PR00313 NodO calcium binding signature 1373 1381 2.0E-7 T 28-03-2018 A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 PRINTS PR00313 NodO calcium binding signature 1364 1372 2.0E-7 T 28-03-2018 A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 PRINTS PR00313 NodO calcium binding signature 1248 1259 2.0E-7 T 28-03-2018 A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 PRINTS PR00313 NodO calcium binding signature 1382 1391 2.0E-7 T 28-03-2018 A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1360 1378 - T 28-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 Gene3D G3DSA:2.60.120.640 1076 1192 2.1E-10 T 28-03-2018 A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 Gene3D G3DSA:2.60.120.640 644 746 0.049 T 28-03-2018 A6A12_RS06470 d0a96d31a7acb785e5cf77c565a9b76b 1492 Gene3D G3DSA:2.150.10.10 1272 1491 1.2E-25 T 28-03-2018 A6A12_RS12810 7ca70e9b3b6928a92332861ff06ce245 125 Pfam PF02313 Fumarate reductase subunit D 11 123 3.0E-44 T 28-03-2018 IPR003418 Fumarate reductase, subunit D GO:0006106|GO:0016020 A6A12_RS12810 7ca70e9b3b6928a92332861ff06ce245 125 ProDom PD015693 FUMARATE MEMBRANE REDUCTASE D SUBUNIT INNER TRANSMEMBRANE HYDROPHOBIC REDUCTASE POLYPEPTIDE 11 125 3.0E-58 T 28-03-2018 IPR003418 Fumarate reductase, subunit D GO:0006106|GO:0016020 A6A12_RS12810 7ca70e9b3b6928a92332861ff06ce245 125 Hamap MF_00709 Fumarate reductase subunit D [frdD]. 7 125 24.558 T 28-03-2018 IPR003418 Fumarate reductase, subunit D GO:0006106|GO:0016020 A6A12_RS12810 7ca70e9b3b6928a92332861ff06ce245 125 SUPERFAMILY SSF81343 7 125 1.33E-50 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS12810 7ca70e9b3b6928a92332861ff06ce245 125 Gene3D G3DSA:1.20.1300.10 6 125 6.5E-24 T 28-03-2018 A6A12_RS12810 7ca70e9b3b6928a92332861ff06ce245 125 PIRSF PIRSF000179 6 125 5.1E-56 T 28-03-2018 IPR003418 Fumarate reductase, subunit D GO:0006106|GO:0016020 A6A12_RS10335 00696d81338907b914be7051fcbf2fb6 180 SUPERFAMILY SSF55021 87 176 1.24E-21 T 28-03-2018 A6A12_RS10335 00696d81338907b914be7051fcbf2fb6 180 Pfam PF13740 ACT domain 3 78 1.9E-24 T 28-03-2018 A6A12_RS10335 00696d81338907b914be7051fcbf2fb6 180 SUPERFAMILY SSF55021 1 84 3.1E-18 T 28-03-2018 A6A12_RS10335 00696d81338907b914be7051fcbf2fb6 180 PIRSF PIRSF028103 1 178 1.9E-62 T 28-03-2018 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 A6A12_RS10335 00696d81338907b914be7051fcbf2fb6 180 Gene3D G3DSA:3.30.70.260 1 88 2.2E-10 T 28-03-2018 A6A12_RS10335 00696d81338907b914be7051fcbf2fb6 180 Gene3D G3DSA:3.30.70.260 89 175 2.5E-13 T 28-03-2018 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 SUPERFAMILY SSF55874 516 684 1.02E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 Gene3D G3DSA:1.10.287.130 449 523 2.3E-16 T 28-03-2018 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 SMART SM00448 722 835 1.7E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 SMART SM00091 873 938 9.2E-5 T 28-03-2018 IPR000014 PAS domain A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 Pfam PF00072 Response regulator receiver domain 725 835 2.4E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 574 683 1.9E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 Pfam PF00989 PAS fold 876 926 5.1E-6 T 28-03-2018 IPR013767 PAS fold GO:0006355 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 SMART SM00387 573 684 7.4E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 SMART SM00388 459 527 2.2E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 Gene3D G3DSA:3.30.450.20 852 963 1.0E-9 T 28-03-2018 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 Pfam PF00512 His Kinase A (phospho-acceptor) domain 460 525 4.4E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 Gene3D G3DSA:3.30.565.10 531 686 3.5E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 PRINTS PR00344 Bacterial sensor protein C-terminal signature 668 681 1.9E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 PRINTS PR00344 Bacterial sensor protein C-terminal signature 627 637 1.9E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 PRINTS PR00344 Bacterial sensor protein C-terminal signature 609 623 1.9E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 PRINTS PR00344 Bacterial sensor protein C-terminal signature 644 662 1.9E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 SUPERFAMILY SSF47384 445 527 5.3E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 Pfam PF00672 HAMP domain 379 427 8.2E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 SUPERFAMILY SSF158472 378 428 2.35E-11 T 28-03-2018 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 Gene3D G3DSA:3.40.50.2300 709 851 6.0E-41 T 28-03-2018 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 SMART SM00304 377 430 8.0E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 SUPERFAMILY SSF55785 861 933 3.84E-8 T 28-03-2018 IPR000014 PAS domain A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 SUPERFAMILY SSF52172 716 852 7.12E-40 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS02850 90a7a24d34df816682019b278c6979d4 1130 Gene3D G3DSA:3.30.450.20 149 356 1.3E-7 T 28-03-2018 A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 Gene3D G3DSA:3.30.70.260 1 82 4.5E-10 T 28-03-2018 A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 Pfam PF00989 PAS fold 84 130 1.8E-5 T 28-03-2018 IPR013767 PAS fold GO:0006355 A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 229 242 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 SUPERFAMILY SSF52540 205 443 3.55E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 Gene3D G3DSA:3.30.450.20 83 190 1.6E-8 T 28-03-2018 A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 Gene3D G3DSA:1.10.8.60 377 467 3.4E-17 T 28-03-2018 A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 Gene3D G3DSA:3.40.50.300 201 376 9.0E-24 T 28-03-2018 A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 Gene3D G3DSA:1.10.10.60 468 513 2.1E-7 T 28-03-2018 A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 SUPERFAMILY SSF55785 83 168 1.58E-9 T 28-03-2018 IPR000014 PAS domain A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 SUPERFAMILY SSF55021 1 68 9.16E-7 T 28-03-2018 A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 417 426 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 290 305 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 SMART SM00382 225 368 3.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 Pfam PF00158 Sigma-54 interaction domain 206 370 2.6E-56 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 SUPERFAMILY SSF46689 460 512 5.5E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 465 513 3.3E-28 T 28-03-2018 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 A6A12_RS07320 161825e73b137c782d5752bc47ea2b1e 514 SMART SM00091 80 146 7.3E-7 T 28-03-2018 IPR000014 PAS domain A6A12_RS07460 f7c5b0df860a6f305f0fd4aeddd9da57 627 SMART SM00283 365 626 6.8E-65 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS07460 f7c5b0df860a6f305f0fd4aeddd9da57 627 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 421 593 1.3E-38 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS07460 f7c5b0df860a6f305f0fd4aeddd9da57 627 Gene3D G3DSA:3.30.450.20 60 154 1.1E-26 T 28-03-2018 A6A12_RS07460 f7c5b0df860a6f305f0fd4aeddd9da57 627 Gene3D G3DSA:3.30.450.20 155 272 4.9E-24 T 28-03-2018 A6A12_RS07460 f7c5b0df860a6f305f0fd4aeddd9da57 627 Pfam PF02743 Cache domain 40 258 4.6E-32 T 28-03-2018 IPR033479 Double Cache domain 1 A6A12_RS07460 f7c5b0df860a6f305f0fd4aeddd9da57 627 SUPERFAMILY SSF103190 76 175 1.54E-12 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A6A12_RS07460 f7c5b0df860a6f305f0fd4aeddd9da57 627 SUPERFAMILY SSF58104 318 627 1.31E-76 T 28-03-2018 A6A12_RS07460 f7c5b0df860a6f305f0fd4aeddd9da57 627 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 463 490 4.1E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07460 f7c5b0df860a6f305f0fd4aeddd9da57 627 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 273 293 4.1E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07460 f7c5b0df860a6f305f0fd4aeddd9da57 627 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 492 521 4.1E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07460 f7c5b0df860a6f305f0fd4aeddd9da57 627 Gene3D G3DSA:1.10.287.950 400 627 3.8E-53 T 28-03-2018 A6A12_RS07460 f7c5b0df860a6f305f0fd4aeddd9da57 627 Gene3D G3DSA:1.10.287.950 300 399 1.1E-5 T 28-03-2018 A6A12_RS07460 f7c5b0df860a6f305f0fd4aeddd9da57 627 Pfam PF00672 HAMP domain 300 345 4.9E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS07460 f7c5b0df860a6f305f0fd4aeddd9da57 627 SMART SM00304 296 350 4.5E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS07460 f7c5b0df860a6f305f0fd4aeddd9da57 627 SMART SM00304 353 403 9.8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS09090 b028ba0831a8d196afe7cc4e1c606589 663 Gene3D G3DSA:1.10.287.850 358 436 0.0063 T 28-03-2018 A6A12_RS09090 b028ba0831a8d196afe7cc4e1c606589 663 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 471 627 4.3E-43 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS09090 b028ba0831a8d196afe7cc4e1c606589 663 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 422 451 7.4E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS09090 b028ba0831a8d196afe7cc4e1c606589 663 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 499 526 7.4E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS09090 b028ba0831a8d196afe7cc4e1c606589 663 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 528 557 7.4E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS09090 b028ba0831a8d196afe7cc4e1c606589 663 SMART SM00283 401 662 6.6E-73 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS09090 b028ba0831a8d196afe7cc4e1c606589 663 Gene3D G3DSA:1.10.287.620 70 309 2.1E-4 T 28-03-2018 A6A12_RS09090 b028ba0831a8d196afe7cc4e1c606589 663 SUPERFAMILY SSF58104 354 663 1.44E-72 T 28-03-2018 A6A12_RS09090 b028ba0831a8d196afe7cc4e1c606589 663 SMART SM00304 334 386 1.8E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS09090 b028ba0831a8d196afe7cc4e1c606589 663 Gene3D G3DSA:1.10.287.950 437 663 3.4E-50 T 28-03-2018 A6A12_RS09115 7cfd19f199dfb9d32faaa7b9d61302b6 235 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 13 183 2.0E-50 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A6A12_RS09115 7cfd19f199dfb9d32faaa7b9d61302b6 235 SUPERFAMILY SSF52540 8 220 4.87E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09115 7cfd19f199dfb9d32faaa7b9d61302b6 235 PIRSF PIRSF006755 8 233 2.7E-74 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A6A12_RS09115 7cfd19f199dfb9d32faaa7b9d61302b6 235 Gene3D G3DSA:3.40.50.300 9 226 3.5E-56 T 28-03-2018 A6A12_RS09115 7cfd19f199dfb9d32faaa7b9d61302b6 235 Pfam PF13500 AAA domain 11 219 4.2E-34 T 28-03-2018 A6A12_RS09115 7cfd19f199dfb9d32faaa7b9d61302b6 235 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 9 217 27.891 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 A6A12_RS09220 06d36070cf296c7c679125bb89a7268f 554 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 94 473 1.3E-93 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain A6A12_RS09220 06d36070cf296c7c679125bb89a7268f 554 PIRSF PIRSF002741 11 554 1.2E-118 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A6A12_RS09220 06d36070cf296c7c679125bb89a7268f 554 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 99 120 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site A6A12_RS09220 06d36070cf296c7c679125bb89a7268f 554 Gene3D G3DSA:3.10.105.10 318 523 9.8E-56 T 28-03-2018 A6A12_RS09220 06d36070cf296c7c679125bb89a7268f 554 SUPERFAMILY SSF53850 49 541 2.17E-148 T 28-03-2018 A6A12_RS09220 06d36070cf296c7c679125bb89a7268f 554 Gene3D G3DSA:3.90.76.10 61 220 5.0E-40 T 28-03-2018 A6A12_RS09220 06d36070cf296c7c679125bb89a7268f 554 Gene3D G3DSA:3.40.190.10 221 317 5.5E-26 T 28-03-2018 A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 SMART SM00388 205 272 2.2E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 426 5.9E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 382 5.9E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 407 5.9E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 368 5.9E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 SUPERFAMILY SSF55785 86 197 3.32E-11 T 28-03-2018 IPR000014 PAS domain A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 Pfam PF00989 PAS fold 99 168 1.3E-7 T 28-03-2018 IPR013767 PAS fold GO:0006355 A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 99 204 1.8E-6 T 28-03-2018 IPR000014 PAS domain A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 SUPERFAMILY SSF55874 261 427 4.45E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 Pfam PF00512 His Kinase A (phospho-acceptor) domain 205 271 5.3E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 SUPERFAMILY SSF47384 192 271 1.65E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 Gene3D G3DSA:3.30.450.20 97 210 2.3E-15 T 28-03-2018 A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 318 427 7.2E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 SMART SM00091 98 164 9.1E-6 T 28-03-2018 IPR000014 PAS domain A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 Pfam PF11808 Domain of unknown function (DUF3329) 7 91 3.6E-30 T 28-03-2018 IPR021766 Protein of unknown function DUF3329 GO:0004673 A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 Gene3D G3DSA:1.10.287.130 211 255 1.0E-15 T 28-03-2018 A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 SMART SM00387 317 429 8.3E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 Gene3D G3DSA:3.30.565.10 256 427 1.7E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS03390 c20eb19ef009a4ae3207b7831c995301 433 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 94 425 5.3E-137 T 28-03-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 A6A12_RS12455 cfffd358fed4b796e261a7a427e9034b 123 SUPERFAMILY SSF50193 2 122 9.42E-52 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A6A12_RS12455 cfffd358fed4b796e261a7a427e9034b 123 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 123 28.557 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A6A12_RS12455 cfffd358fed4b796e261a7a427e9034b 123 Pfam PF00238 Ribosomal protein L14p/L23e 1 123 4.6E-55 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A6A12_RS12455 cfffd358fed4b796e261a7a427e9034b 123 Gene3D G3DSA:2.40.150.20 1 123 3.4E-53 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A6A12_RS12455 cfffd358fed4b796e261a7a427e9034b 123 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 123 4.8E-59 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 A6A12_RS12455 cfffd358fed4b796e261a7a427e9034b 123 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12455 cfffd358fed4b796e261a7a427e9034b 123 SMART SM01374 1 123 3.3E-86 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A6A12_RS12745 cadbe6ec9f81b2e306bc7e2de51f5480 261 TIGRFAM TIGR00761 argB: acetylglutamate kinase 9 232 4.3E-63 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A6A12_RS12745 cadbe6ec9f81b2e306bc7e2de51f5480 261 SUPERFAMILY SSF53633 6 260 5.37E-58 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS12745 cadbe6ec9f81b2e306bc7e2de51f5480 261 Pfam PF00696 Amino acid kinase family 9 236 2.6E-34 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS12745 cadbe6ec9f81b2e306bc7e2de51f5480 261 Gene3D G3DSA:3.40.1160.10 1 261 4.9E-46 T 28-03-2018 A6A12_RS12745 cadbe6ec9f81b2e306bc7e2de51f5480 261 Hamap MF_00082_B Acetylglutamate kinase [argB]. 5 260 26.31 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A6A12_RS12745 cadbe6ec9f81b2e306bc7e2de51f5480 261 PIRSF PIRSF000728 1 261 2.5E-69 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A6A12_RS05125 e10bbd38e63216a342b26478d8231471 455 Gene3D G3DSA:1.10.4100.10 265 430 1.7E-29 T 28-03-2018 A6A12_RS05125 e10bbd38e63216a342b26478d8231471 455 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 447 1.1E-196 T 28-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A6A12_RS05125 e10bbd38e63216a342b26478d8231471 455 Pfam PF03313 Serine dehydratase alpha chain 181 446 1.0E-94 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit A6A12_RS05125 e10bbd38e63216a342b26478d8231471 455 Pfam PF03315 Serine dehydratase beta chain 3 152 2.4E-52 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A6A12_RS05125 e10bbd38e63216a342b26478d8231471 455 Gene3D G3DSA:3.30.1330.90 10 155 1.1E-50 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A6A12_RS05125 e10bbd38e63216a342b26478d8231471 455 SUPERFAMILY SSF143548 16 154 2.33E-43 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A6A12_RS09930 1096b9fd3a403c996ebca3f1a90bf82c 697 Pfam PF00771 FHIPEP family 32 687 1.5E-269 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A6A12_RS09930 1096b9fd3a403c996ebca3f1a90bf82c 697 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 147 170 - T 28-03-2018 IPR025505 FHIPEP conserved site A6A12_RS09930 1096b9fd3a403c996ebca3f1a90bf82c 697 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 22 694 7.6E-267 T 28-03-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 A6A12_RS09930 1096b9fd3a403c996ebca3f1a90bf82c 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 161 179 2.4E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A6A12_RS09930 1096b9fd3a403c996ebca3f1a90bf82c 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 75 94 2.4E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A6A12_RS09930 1096b9fd3a403c996ebca3f1a90bf82c 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 242 256 2.4E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A6A12_RS09930 1096b9fd3a403c996ebca3f1a90bf82c 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 142 158 2.4E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A6A12_RS09930 1096b9fd3a403c996ebca3f1a90bf82c 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 191 208 2.4E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A6A12_RS09930 1096b9fd3a403c996ebca3f1a90bf82c 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 38 51 2.4E-56 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A6A12_RS09930 1096b9fd3a403c996ebca3f1a90bf82c 697 PIRSF PIRSF005419 10 697 4.5E-254 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 A6A12_RS09280 73f4c7f66c80fcf7c381a126ff69b7f2 461 Pfam PF00501 AMP-binding enzyme 25 308 2.5E-16 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A6A12_RS09280 73f4c7f66c80fcf7c381a126ff69b7f2 461 Gene3D G3DSA:3.40.50.980 152 305 5.5E-18 T 28-03-2018 A6A12_RS09280 73f4c7f66c80fcf7c381a126ff69b7f2 461 Gene3D G3DSA:3.30.300.30 351 460 3.3E-15 T 28-03-2018 A6A12_RS09280 73f4c7f66c80fcf7c381a126ff69b7f2 461 Gene3D G3DSA:3.40.50.980 14 151 6.1E-7 T 28-03-2018 A6A12_RS09280 73f4c7f66c80fcf7c381a126ff69b7f2 461 SUPERFAMILY SSF56801 28 456 1.16E-51 T 28-03-2018 A6A12_RS01035 293a61ea99dc1f3a872b409841e1afd8 497 Hamap MF_01550 Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [gppA]. 2 495 58.46 T 28-03-2018 IPR023709 Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase GO:0008894|GO:0015974 KEGG: 00230+3.6.1.40 A6A12_RS01035 293a61ea99dc1f3a872b409841e1afd8 497 PIRSF PIRSF001267 1 496 1.9E-180 T 28-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 A6A12_RS01035 293a61ea99dc1f3a872b409841e1afd8 497 Pfam PF02541 Ppx/GppA phosphatase family 23 303 5.7E-87 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 A6A12_RS01035 293a61ea99dc1f3a872b409841e1afd8 497 SUPERFAMILY SSF109604 309 494 4.87E-43 T 28-03-2018 A6A12_RS01035 293a61ea99dc1f3a872b409841e1afd8 497 SUPERFAMILY SSF53067 9 129 8.36E-37 T 28-03-2018 A6A12_RS01035 293a61ea99dc1f3a872b409841e1afd8 497 Gene3D G3DSA:3.30.420.40 1 122 7.0E-38 T 28-03-2018 A6A12_RS01035 293a61ea99dc1f3a872b409841e1afd8 497 Gene3D G3DSA:3.30.420.150 123 301 2.0E-33 T 28-03-2018 A6A12_RS01035 293a61ea99dc1f3a872b409841e1afd8 497 SUPERFAMILY SSF53067 135 304 3.7E-43 T 28-03-2018 A6A12_RS04225 bc27a29fed05f014607bc799d9c0e6c0 443 SMART SM00984 320 424 1.7E-46 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A6A12_RS04225 bc27a29fed05f014607bc799d9c0e6c0 443 SUPERFAMILY SSF48179 204 301 4.08E-34 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A6A12_RS04225 bc27a29fed05f014607bc799d9c0e6c0 443 Gene3D G3DSA:3.40.50.720 1 201 1.1E-60 T 28-03-2018 A6A12_RS04225 bc27a29fed05f014607bc799d9c0e6c0 443 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 187 2.0E-63 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A6A12_RS04225 bc27a29fed05f014607bc799d9c0e6c0 443 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 295 5.1E-39 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A6A12_RS04225 bc27a29fed05f014607bc799d9c0e6c0 443 PIRSF PIRSF500134 1 442 7.4E-190 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 A6A12_RS04225 bc27a29fed05f014607bc799d9c0e6c0 443 Gene3D G3DSA:3.40.50.720 228 436 2.4E-72 T 28-03-2018 A6A12_RS04225 bc27a29fed05f014607bc799d9c0e6c0 443 PIRSF PIRSF000124 1 439 1.2E-147 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A6A12_RS04225 bc27a29fed05f014607bc799d9c0e6c0 443 SUPERFAMILY SSF51735 1 195 6.17E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS04225 bc27a29fed05f014607bc799d9c0e6c0 443 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 420 1.0E-142 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A6A12_RS04225 bc27a29fed05f014607bc799d9c0e6c0 443 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 424 5.6E-31 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A6A12_RS04225 bc27a29fed05f014607bc799d9c0e6c0 443 Gene3D G3DSA:1.20.5.100 205 227 1.1E-14 T 28-03-2018 A6A12_RS04225 bc27a29fed05f014607bc799d9c0e6c0 443 SUPERFAMILY SSF52413 308 435 3.14E-38 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A6A12_RS05965 873e52f6cb8860b386032cadc2c17b92 484 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 12 484 8.4E-155 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 A6A12_RS05965 873e52f6cb8860b386032cadc2c17b92 484 Pfam PF13091 PLD-like domain 134 268 8.4E-16 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A6A12_RS05965 873e52f6cb8860b386032cadc2c17b92 484 Pfam PF13091 PLD-like domain 327 445 4.3E-24 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A6A12_RS05965 873e52f6cb8860b386032cadc2c17b92 484 PIRSF PIRSF000850 288 376 0.0033 T 28-03-2018 A6A12_RS05965 873e52f6cb8860b386032cadc2c17b92 484 PIRSF PIRSF000850 388 475 0.21 T 28-03-2018 A6A12_RS05965 873e52f6cb8860b386032cadc2c17b92 484 PIRSF PIRSF000850 108 252 25.0 T 28-03-2018 A6A12_RS05965 873e52f6cb8860b386032cadc2c17b92 484 SUPERFAMILY SSF56024 69 313 6.5E-52 T 28-03-2018 A6A12_RS05965 873e52f6cb8860b386032cadc2c17b92 484 Pfam PF13396 Phospholipase_D-nuclease N-terminal 21 59 4.6E-7 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal A6A12_RS05965 873e52f6cb8860b386032cadc2c17b92 484 Hamap MF_00190 Cardiolipin synthase A [clsA]. 2 484 50.045 T 28-03-2018 IPR030840 Cardiolipin synthase A GO:0008808|GO:0016780|GO:0032049 A6A12_RS05965 873e52f6cb8860b386032cadc2c17b92 484 SMART SM00155 219 246 6.1E-6 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A6A12_RS05965 873e52f6cb8860b386032cadc2c17b92 484 SMART SM00155 397 424 4.0E-6 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A6A12_RS05965 873e52f6cb8860b386032cadc2c17b92 484 SUPERFAMILY SSF56024 274 471 1.88E-44 T 28-03-2018 A6A12_RS05965 873e52f6cb8860b386032cadc2c17b92 484 Gene3D G3DSA:3.30.870.10 314 468 1.1E-22 T 28-03-2018 A6A12_RS05965 873e52f6cb8860b386032cadc2c17b92 484 Gene3D G3DSA:3.30.870.10 99 290 6.9E-30 T 28-03-2018 A6A12_RS07570 236f38a0f79440fc9612c1b500052265 260 Gene3D G3DSA:3.40.50.300 3 248 9.8E-52 T 28-03-2018 A6A12_RS07570 236f38a0f79440fc9612c1b500052265 260 SUPERFAMILY SSF52540 5 240 2.2E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS07570 236f38a0f79440fc9612c1b500052265 260 Pfam PF00005 ABC transporter 22 171 2.7E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS07570 236f38a0f79440fc9612c1b500052265 260 SMART SM00382 31 220 1.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS01190 63652112d608be7da3997752f135f13b 1400 SMART SM00663 235 514 8.5E-185 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01190 63652112d608be7da3997752f135f13b 1400 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1376 18.944 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01190 63652112d608be7da3997752f135f13b 1400 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 644 1.1E-27 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01190 63652112d608be7da3997752f135f13b 1400 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1366 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01190 63652112d608be7da3997752f135f13b 1400 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1314 2.8E-77 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01190 63652112d608be7da3997752f135f13b 1400 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 763 2.2E-19 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01190 63652112d608be7da3997752f135f13b 1400 Gene3D G3DSA:2.40.50.100 1153 1212 1.2E-14 T 28-03-2018 A6A12_RS01190 63652112d608be7da3997752f135f13b 1400 Gene3D G3DSA:2.40.40.20 346 488 5.5E-40 T 28-03-2018 A6A12_RS01190 63652112d608be7da3997752f135f13b 1400 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 1.7E-87 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01190 63652112d608be7da3997752f135f13b 1400 SUPERFAMILY SSF64484 1133 1362 0.0 T 28-03-2018 A6A12_RS01190 63652112d608be7da3997752f135f13b 1400 SUPERFAMILY SSF64484 16 944 0.0 T 28-03-2018 A6A12_RS01190 63652112d608be7da3997752f135f13b 1400 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 393 6.4E-8 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01190 63652112d608be7da3997752f135f13b 1400 Pfam PF00623 RNA polymerase Rpb1, domain 2 388 485 1.2E-27 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01190 63652112d608be7da3997752f135f13b 1400 Gene3D G3DSA:2.40.50.100 1022 1126 2.1E-13 T 28-03-2018 A6A12_RS01190 63652112d608be7da3997752f135f13b 1400 Gene3D G3DSA:2.40.50.100 907 1021 2.0E-28 T 28-03-2018 A6A12_RS13115 ab4bc9522e350c6723383ec02fb60f59 98 Gene3D G3DSA:1.10.10.60 1 98 1.2E-26 T 28-03-2018 A6A12_RS13115 ab4bc9522e350c6723383ec02fb60f59 98 PIRSF PIRSF002097 1 98 3.0E-44 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 A6A12_RS13115 ab4bc9522e350c6723383ec02fb60f59 98 Pfam PF02954 Bacterial regulatory protein, Fis family 55 95 4.0E-14 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS13115 ab4bc9522e350c6723383ec02fb60f59 98 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 61 78 3.3E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS13115 ab4bc9522e350c6723383ec02fb60f59 98 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 78 98 3.3E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS13115 ab4bc9522e350c6723383ec02fb60f59 98 PRINTS PR01591 DNA-binding protein FIS signature 57 69 1.2E-30 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 A6A12_RS13115 ab4bc9522e350c6723383ec02fb60f59 98 PRINTS PR01591 DNA-binding protein FIS signature 9 26 1.2E-30 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 A6A12_RS13115 ab4bc9522e350c6723383ec02fb60f59 98 PRINTS PR01591 DNA-binding protein FIS signature 26 42 1.2E-30 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 A6A12_RS13115 ab4bc9522e350c6723383ec02fb60f59 98 PRINTS PR01591 DNA-binding protein FIS signature 42 57 1.2E-30 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 A6A12_RS13115 ab4bc9522e350c6723383ec02fb60f59 98 Hamap MF_00166 DNA-binding protein Fis [fis]. 1 98 31.1 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 A6A12_RS13115 ab4bc9522e350c6723383ec02fb60f59 98 SUPERFAMILY SSF46689 8 98 2.02E-24 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS10175 049b6e62d97c1cb3ce0082e8c52d2b53 126 Pfam PF04347 Flagellar biosynthesis protein, FliO 43 121 2.0E-18 T 28-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 A6A12_RS10175 049b6e62d97c1cb3ce0082e8c52d2b53 126 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 31 98 9.6E-23 T 28-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 A6A12_RS10175 049b6e62d97c1cb3ce0082e8c52d2b53 126 ProSitePatterns PS00266 Somatotropin, prolactin and related hormones signature 1. 10 43 - T 28-03-2018 IPR018116 Somatotropin hormone, conserved site GO:0005179|GO:0005576 A6A12_RS03950 bc28039595bb99087666f1b0f49d1ba4 295 Gene3D G3DSA:1.10.10.10 2 84 2.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03950 bc28039595bb99087666f1b0f49d1ba4 295 SUPERFAMILY SSF46785 4 87 2.47E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03950 bc28039595bb99087666f1b0f49d1ba4 295 Gene3D G3DSA:3.40.190.10 176 259 3.2E-24 T 28-03-2018 A6A12_RS03950 bc28039595bb99087666f1b0f49d1ba4 295 Gene3D G3DSA:3.40.190.10 88 175 3.1E-12 T 28-03-2018 A6A12_RS03950 bc28039595bb99087666f1b0f49d1ba4 295 Pfam PF03466 LysR substrate binding domain 88 288 5.3E-46 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS03950 bc28039595bb99087666f1b0f49d1ba4 295 SUPERFAMILY SSF53850 89 290 4.34E-46 T 28-03-2018 A6A12_RS03950 bc28039595bb99087666f1b0f49d1ba4 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 63 1.8E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS11170 7934c2cb44c11ce1595f8a7de2e0d32a 708 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 18 701 49.633 T 28-03-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 A6A12_RS11170 7934c2cb44c11ce1595f8a7de2e0d32a 708 Gene3D G3DSA:3.40.50.300 129 443 8.1E-57 T 28-03-2018 A6A12_RS11170 7934c2cb44c11ce1595f8a7de2e0d32a 708 Pfam PF13604 AAA domain 240 401 2.9E-30 T 28-03-2018 A6A12_RS11170 7934c2cb44c11ce1595f8a7de2e0d32a 708 SUPERFAMILY SSF52540 438 491 1.66E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11170 7934c2cb44c11ce1595f8a7de2e0d32a 708 SUPERFAMILY SSF52540 238 407 1.66E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11170 7934c2cb44c11ce1595f8a7de2e0d32a 708 SUPERFAMILY SSF52540 523 699 1.66E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11170 7934c2cb44c11ce1595f8a7de2e0d32a 708 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 9 703 1.1E-214 T 28-03-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 A6A12_RS11170 7934c2cb44c11ce1595f8a7de2e0d32a 708 Gene3D G3DSA:3.40.50.300 453 692 4.6E-33 T 28-03-2018 A6A12_RS11170 7934c2cb44c11ce1595f8a7de2e0d32a 708 Pfam PF13538 UvrD-like helicase C-terminal domain 632 678 5.6E-14 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 SMART SM00388 282 347 3.7E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 Gene3D G3DSA:3.40.50.2300 522 641 6.3E-26 T 28-03-2018 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 SMART SM00073 679 776 2.8E-9 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 PIRSF PIRSF003182 1 779 0.0 T 28-03-2018 IPR014409 Signal transduction histidine kinase, hybrid-type, aerobic respiration control ArcB GO:0000155|GO:0000160|GO:0004673|GO:0016021 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 448 1.8E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 488 1.8E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 462 1.8E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 507 1.8E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 152 276 4.4E-18 T 28-03-2018 IPR000014 PAS domain A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 Gene3D G3DSA:1.10.287.130 274 343 7.2E-17 T 28-03-2018 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 Pfam PF01627 Hpt domain 690 760 1.4E-10 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 SMART SM00091 155 221 3.2E-7 T 28-03-2018 IPR000014 PAS domain A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 Gene3D G3DSA:1.10.287.970 3 88 5.9E-37 T 28-03-2018 IPR027460 Aerobic respiration control sensor protein ArcB, transmembrane domain A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 SUPERFAMILY SSF55874 336 508 2.36E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 SUPERFAMILY SSF52172 526 643 6.4E-25 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 SUPERFAMILY SSF47226 665 778 9.16E-28 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 Pfam PF00072 Response regulator receiver domain 529 637 1.3E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 Gene3D G3DSA:1.20.120.160 642 767 3.3E-17 T 28-03-2018 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 SUPERFAMILY SSF55785 140 267 1.68E-24 T 28-03-2018 IPR000014 PAS domain A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 SMART SM00448 527 638 3.1E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 SMART SM00387 394 510 8.0E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 Gene3D G3DSA:3.30.565.10 353 518 6.0E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 Gene3D G3DSA:3.30.450.20 134 273 5.0E-26 T 28-03-2018 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 Pfam PF00512 His Kinase A (phospho-acceptor) domain 283 345 4.5E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 395 507 9.1E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 Pfam PF08448 PAS fold 162 271 5.7E-18 T 28-03-2018 IPR013656 PAS fold-4 A6A12_RS11400 93f537c71556f1f65d7e754513df621f 779 SUPERFAMILY SSF47384 270 347 1.16E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS13175 9da020e03a12fe617106745a3ea3c3a6 629 Pfam PF00672 HAMP domain 300 347 3.3E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS13175 9da020e03a12fe617106745a3ea3c3a6 629 SUPERFAMILY SSF58104 320 629 9.16E-78 T 28-03-2018 A6A12_RS13175 9da020e03a12fe617106745a3ea3c3a6 629 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 428 595 3.0E-40 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS13175 9da020e03a12fe617106745a3ea3c3a6 629 SUPERFAMILY SSF103190 89 177 2.17E-10 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A6A12_RS13175 9da020e03a12fe617106745a3ea3c3a6 629 SMART SM00304 298 352 2.8E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS13175 9da020e03a12fe617106745a3ea3c3a6 629 SMART SM00283 367 628 1.5E-70 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS13175 9da020e03a12fe617106745a3ea3c3a6 629 Gene3D G3DSA:3.30.450.20 158 274 4.8E-20 T 28-03-2018 A6A12_RS13175 9da020e03a12fe617106745a3ea3c3a6 629 Gene3D G3DSA:1.10.287.950 407 629 7.4E-53 T 28-03-2018 A6A12_RS13175 9da020e03a12fe617106745a3ea3c3a6 629 Pfam PF02743 Cache domain 36 260 3.6E-24 T 28-03-2018 IPR033479 Double Cache domain 1 A6A12_RS13175 9da020e03a12fe617106745a3ea3c3a6 629 Gene3D G3DSA:3.30.450.20 28 157 2.8E-23 T 28-03-2018 A6A12_RS13175 9da020e03a12fe617106745a3ea3c3a6 629 Gene3D G3DSA:1.10.287.1060 329 406 1.8E-5 T 28-03-2018 A6A12_RS13085 6255c9de4ed97838f358ac2b42634496 649 Gene3D G3DSA:3.40.50.980 74 266 1.7E-53 T 28-03-2018 A6A12_RS13085 6255c9de4ed97838f358ac2b42634496 649 Pfam PF13193 AMP-binding enzyme C-terminal domain 531 609 1.9E-24 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A6A12_RS13085 6255c9de4ed97838f358ac2b42634496 649 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 20 643 0.0 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 A6A12_RS13085 6255c9de4ed97838f358ac2b42634496 649 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 2 645 52.475 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 A6A12_RS13085 6255c9de4ed97838f358ac2b42634496 649 Gene3D G3DSA:2.30.38.10 430 515 9.7E-12 T 28-03-2018 A6A12_RS13085 6255c9de4ed97838f358ac2b42634496 649 Gene3D G3DSA:3.40.50.980 267 429 2.8E-36 T 28-03-2018 A6A12_RS13085 6255c9de4ed97838f358ac2b42634496 649 Pfam PF00501 AMP-binding enzyme 84 522 1.5E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A6A12_RS13085 6255c9de4ed97838f358ac2b42634496 649 Gene3D G3DSA:3.30.300.30 518 648 6.4E-25 T 28-03-2018 A6A12_RS13085 6255c9de4ed97838f358ac2b42634496 649 SUPERFAMILY SSF56801 11 643 7.72E-182 T 28-03-2018 A6A12_RS13085 6255c9de4ed97838f358ac2b42634496 649 ProSitePatterns PS00455 Putative AMP-binding domain signature. 261 272 - T 28-03-2018 IPR020845 AMP-binding, conserved site A6A12_RS13085 6255c9de4ed97838f358ac2b42634496 649 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 24 81 3.4E-20 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 A6A12_RS04325 a07c7d0b486dac77e76bcd17d013eba0 416 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 416 51.819 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A6A12_RS04325 a07c7d0b486dac77e76bcd17d013eba0 416 Gene3D G3DSA:3.40.640.10 37 274 4.4E-55 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS04325 a07c7d0b486dac77e76bcd17d013eba0 416 Pfam PF00464 Serine hydroxymethyltransferase 9 385 2.5E-180 T 28-03-2018 A6A12_RS04325 a07c7d0b486dac77e76bcd17d013eba0 416 PIRSF PIRSF000412 1 415 2.5E-166 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A6A12_RS04325 a07c7d0b486dac77e76bcd17d013eba0 416 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A6A12_RS04325 a07c7d0b486dac77e76bcd17d013eba0 416 SUPERFAMILY SSF53383 6 415 2.31E-182 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS04325 a07c7d0b486dac77e76bcd17d013eba0 416 Gene3D G3DSA:3.90.1150.10 275 414 4.7E-56 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS11730 9bd93e0433c839a76241e9873c599dea 202 Gene3D G3DSA:2.30.30.410 18 85 9.5E-9 T 28-03-2018 A6A12_RS11730 9bd93e0433c839a76241e9873c599dea 202 TIGRFAM TIGR04211 SH3_and_anchor: SH3 domain protein 23 201 2.5E-54 T 28-03-2018 IPR016476 SH3 domain protein A6A12_RS11730 9bd93e0433c839a76241e9873c599dea 202 Gene3D G3DSA:1.20.5.50 86 166 2.5E-7 T 28-03-2018 A6A12_RS11730 9bd93e0433c839a76241e9873c599dea 202 SMART SM00287 19 85 7.1E-11 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type A6A12_RS11730 9bd93e0433c839a76241e9873c599dea 202 PIRSF PIRSF006158 1 202 5.6E-71 T 28-03-2018 IPR016476 SH3 domain protein A6A12_RS11730 9bd93e0433c839a76241e9873c599dea 202 Pfam PF08239 Bacterial SH3 domain 31 81 6.7E-10 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type A6A12_RS11535 a965bc4b544ba741c317dfeb142cea41 439 SUPERFAMILY SSF53623 98 299 6.54E-52 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS11535 a965bc4b544ba741c317dfeb142cea41 439 Pfam PF08245 Mur ligase middle domain 113 281 3.3E-26 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS11535 a965bc4b544ba741c317dfeb142cea41 439 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 8 438 32.946 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS11535 a965bc4b544ba741c317dfeb142cea41 439 SUPERFAMILY SSF51984 8 97 7.19E-18 T 28-03-2018 A6A12_RS11535 a965bc4b544ba741c317dfeb142cea41 439 SUPERFAMILY SSF53244 301 437 1.28E-41 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A6A12_RS11535 a965bc4b544ba741c317dfeb142cea41 439 Pfam PF02875 Mur ligase family, glutamate ligase domain 304 375 5.4E-7 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A6A12_RS11535 a965bc4b544ba741c317dfeb142cea41 439 Gene3D G3DSA:3.90.190.20 302 435 7.7E-30 T 28-03-2018 A6A12_RS11535 a965bc4b544ba741c317dfeb142cea41 439 Gene3D G3DSA:3.40.1190.10 98 301 3.8E-52 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS11535 a965bc4b544ba741c317dfeb142cea41 439 Gene3D G3DSA:3.40.50.720 2 97 1.0E-12 T 28-03-2018 A6A12_RS11535 a965bc4b544ba741c317dfeb142cea41 439 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 9 436 1.1E-130 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 SUPERFAMILY SSF46977 444 583 1.7E-43 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 Gene3D G3DSA:4.10.80.40 543 576 6.4E-12 T 28-03-2018 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 8.5E-5 T 28-03-2018 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 375 382 8.5E-5 T 28-03-2018 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 Gene3D G3DSA:1.20.58.100 423 538 1.8E-29 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 PIRSF PIRSF000171 1 574 4.3E-44 T 28-03-2018 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 SUPERFAMILY SSF51905 3 250 8.53E-74 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 SUPERFAMILY SSF51905 361 440 8.53E-74 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 Pfam PF00890 FAD binding domain 7 397 9.1E-114 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 581 8.5E-236 T 28-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 Gene3D G3DSA:3.50.50.60 4 277 7.7E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 43 52 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 SUPERFAMILY SSF56425 227 358 2.39E-41 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 Pfam PF02910 Fumarate reductase flavoprotein C-term 453 581 1.0E-37 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 360 382 1.7E-9 T 28-03-2018 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.7E-9 T 28-03-2018 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 TIGRFAM TIGR01176 fum_red_Fp: fumarate reductase (quinol), flavoprotein subunit 3 582 0.0 T 28-03-2018 IPR005884 Fumarate reductase, flavoprotein subunit GO:0009061|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.4|KEGG: 00620+1.3.5.4|KEGG: 00650+1.3.5.4|KEGG: 00720+1.3.5.4|MetaCyc: PWY-5392|MetaCyc: PWY-5913|MetaCyc: PWY-7384 A6A12_RS12795 142ebb19c4de500c3957468576836ea9 604 Gene3D G3DSA:3.50.50.60 311 415 2.0E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS11180 2b3ba8170b9eb06569d975cb7c17574e 1147 Gene3D G3DSA:1.10.10.160 86 185 8.3E-34 T 28-03-2018 A6A12_RS11180 2b3ba8170b9eb06569d975cb7c17574e 1147 SUPERFAMILY SSF52540 372 815 8.5E-102 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11180 2b3ba8170b9eb06569d975cb7c17574e 1147 Gene3D G3DSA:1.10.486.10 444 656 2.7E-70 T 28-03-2018 A6A12_RS11180 2b3ba8170b9eb06569d975cb7c17574e 1147 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 2 811 1.4E-298 T 28-03-2018 A6A12_RS11180 2b3ba8170b9eb06569d975cb7c17574e 1147 SUPERFAMILY SSF52540 2 352 4.51E-121 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11180 2b3ba8170b9eb06569d975cb7c17574e 1147 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 1 1107 20.749 T 28-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 A6A12_RS11180 2b3ba8170b9eb06569d975cb7c17574e 1147 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 2 1107 0.0 T 28-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 A6A12_RS11180 2b3ba8170b9eb06569d975cb7c17574e 1147 SUPERFAMILY SSF52980 838 1133 3.06E-75 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A6A12_RS11180 2b3ba8170b9eb06569d975cb7c17574e 1147 PIRSF PIRSF000980 1 1145 0.0 T 28-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 A6A12_RS09745 d2961284af3dcf25c42a610d4f2f3566 376 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 372 31.876 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS09745 d2961284af3dcf25c42a610d4f2f3566 376 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 148 358 3.8E-57 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A6A12_RS09745 d2961284af3dcf25c42a610d4f2f3566 376 SMART SM00859 2 126 1.4E-19 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A6A12_RS09745 d2961284af3dcf25c42a610d4f2f3566 376 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 1 371 3.8E-186 T 28-03-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS09745 d2961284af3dcf25c42a610d4f2f3566 376 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 124 9.2E-22 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A6A12_RS09745 d2961284af3dcf25c42a610d4f2f3566 376 SUPERFAMILY SSF55347 138 359 3.27E-78 T 28-03-2018 A6A12_RS09745 d2961284af3dcf25c42a610d4f2f3566 376 Gene3D G3DSA:3.40.50.720 1 148 1.1E-16 T 28-03-2018 A6A12_RS09745 d2961284af3dcf25c42a610d4f2f3566 376 PIRSF PIRSF000148 1 376 8.7E-65 T 28-03-2018 A6A12_RS09745 d2961284af3dcf25c42a610d4f2f3566 376 Gene3D G3DSA:3.30.360.10 149 355 6.0E-61 T 28-03-2018 A6A12_RS09745 d2961284af3dcf25c42a610d4f2f3566 376 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 266 280 - T 28-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS09745 d2961284af3dcf25c42a610d4f2f3566 376 SUPERFAMILY SSF51735 1 151 3.23E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS06125 0dad34d653670d6b723917a5d873c2a7 389 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 13 387 23.534 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 A6A12_RS06125 0dad34d653670d6b723917a5d873c2a7 389 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 16 381 4.1E-184 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 A6A12_RS06125 0dad34d653670d6b723917a5d873c2a7 389 Gene3D G3DSA:1.20.1530.10 11 387 2.0E-145 T 28-03-2018 IPR023171 Na/H antiporter domain A6A12_RS06125 0dad34d653670d6b723917a5d873c2a7 389 Pfam PF06965 Na+/H+ antiporter 1 15 381 1.9E-143 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 A6A12_RS02445 a1207bd0e9953134d7f029bbea133381 375 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS02445 a1207bd0e9953134d7f029bbea133381 375 Pfam PF12857 TOBE-like domain 288 345 1.5E-11 T 28-03-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 A6A12_RS02445 a1207bd0e9953134d7f029bbea133381 375 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 242 9.5E-115 T 28-03-2018 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 A6A12_RS02445 a1207bd0e9953134d7f029bbea133381 375 SUPERFAMILY SSF50331 240 344 4.14E-6 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A6A12_RS02445 a1207bd0e9953134d7f029bbea133381 375 Pfam PF00005 ABC transporter 18 164 5.0E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS02445 a1207bd0e9953134d7f029bbea133381 375 SMART SM00382 27 214 1.5E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS02445 a1207bd0e9953134d7f029bbea133381 375 Gene3D G3DSA:2.40.50.100 285 345 6.0E-4 T 28-03-2018 A6A12_RS02445 a1207bd0e9953134d7f029bbea133381 375 SUPERFAMILY SSF52540 3 246 7.38E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS02445 a1207bd0e9953134d7f029bbea133381 375 Gene3D G3DSA:3.40.50.300 1 284 6.2E-76 T 28-03-2018 A6A12_RS08390 5c03f84a701c1a0277e35ff62c28e5ae 112 Pfam PF05939 Phage minor tail protein 5 110 1.9E-31 T 28-03-2018 IPR010265 Bacteriophage lambda, GpM, minor tail A6A12_RS03850 971d00d7bb6550334b3a0e65c52b301f 412 Pfam PF13356 Arm DNA-binding domain 8 93 3.7E-17 T 28-03-2018 IPR025166 Integrase, DNA-binding domain A6A12_RS03850 971d00d7bb6550334b3a0e65c52b301f 412 Gene3D G3DSA:1.10.150.130 96 210 2.3E-21 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A6A12_RS03850 971d00d7bb6550334b3a0e65c52b301f 412 Pfam PF00589 Phage integrase family 214 376 7.0E-27 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS03850 971d00d7bb6550334b3a0e65c52b301f 412 Gene3D G3DSA:1.10.443.10 211 391 2.9E-27 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS03850 971d00d7bb6550334b3a0e65c52b301f 412 SUPERFAMILY SSF56349 106 386 7.65E-61 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS05230 4d8b75600ab5d77ebbd729798dabb3b8 94 Pfam PF00216 Bacterial DNA-binding protein 1 91 4.6E-29 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS05230 4d8b75600ab5d77ebbd729798dabb3b8 94 Gene3D G3DSA:4.10.520.10 1 94 1.4E-31 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A6A12_RS05230 4d8b75600ab5d77ebbd729798dabb3b8 94 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 9.5E-18 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS05230 4d8b75600ab5d77ebbd729798dabb3b8 94 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 9.5E-18 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS05230 4d8b75600ab5d77ebbd729798dabb3b8 94 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 9.5E-18 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS05230 4d8b75600ab5d77ebbd729798dabb3b8 94 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A6A12_RS05230 4d8b75600ab5d77ebbd729798dabb3b8 94 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 30.317 T 28-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 A6A12_RS05230 4d8b75600ab5d77ebbd729798dabb3b8 94 SUPERFAMILY SSF47729 1 91 4.42E-30 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A6A12_RS05230 4d8b75600ab5d77ebbd729798dabb3b8 94 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 92 4.7E-48 T 28-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 A6A12_RS05230 4d8b75600ab5d77ebbd729798dabb3b8 94 SMART SM00411 1 91 5.0E-40 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS08295 bfa6faa0549d4cd24e97cc0bff048b1e 297 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 15 192 9.4E-11 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A6A12_RS08295 bfa6faa0549d4cd24e97cc0bff048b1e 297 PIRSF PIRSF006278 3 295 1.6E-21 T 28-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase A6A12_RS08295 bfa6faa0549d4cd24e97cc0bff048b1e 297 Gene3D G3DSA:3.40.50.1100 33 136 2.5E-15 T 28-03-2018 A6A12_RS08295 bfa6faa0549d4cd24e97cc0bff048b1e 297 SUPERFAMILY SSF53686 8 294 8.83E-55 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 Gene3D G3DSA:1.10.460.10 482 650 9.8E-23 T 28-03-2018 A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 Pfam PF01131 DNA topoisomerase 159 598 4.1E-111 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 SUPERFAMILY SSF56712 3 612 6.67E-181 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 Gene3D G3DSA:1.10.460.10 162 364 2.9E-38 T 28-03-2018 A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 SMART SM00437 284 563 2.2E-86 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 SMART SM00493 2 125 8.4E-27 T 28-03-2018 IPR006171 TOPRIM domain A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 Hamap MF_00953 DNA topoisomerase 3 [topB]. 2 647 65.279 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 Pfam PF01751 Toprim domain 4 127 7.2E-16 T 28-03-2018 IPR006171 TOPRIM domain A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 321 336 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 SMART SM00436 129 224 1.3E-30 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 640 1.8E-236 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 3.4E-26 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 526 540 3.4E-26 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 327 336 3.4E-26 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 194 212 3.4E-26 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 408 424 3.4E-26 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 Gene3D G3DSA:2.70.20.10 371 481 6.4E-24 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A6A12_RS09800 050d524810d226e35a930dcae3caf71c 650 Gene3D G3DSA:3.40.50.140 2 157 6.0E-37 T 28-03-2018 A6A12_RS10845 0bc0db4576e43c4ec90d5fd34ff289fa 382 Gene3D G3DSA:3.40.50.2000 174 367 4.8E-11 T 28-03-2018 A6A12_RS10845 0bc0db4576e43c4ec90d5fd34ff289fa 382 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 7 381 41.373 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 A6A12_RS10845 0bc0db4576e43c4ec90d5fd34ff289fa 382 Pfam PF02684 Lipid-A-disaccharide synthetase 10 375 5.4E-128 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 A6A12_RS10845 0bc0db4576e43c4ec90d5fd34ff289fa 382 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 5 379 1.7E-135 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 A6A12_RS10845 0bc0db4576e43c4ec90d5fd34ff289fa 382 SUPERFAMILY SSF53756 9 380 9.42E-30 T 28-03-2018 A6A12_RS02650 b32e55bc05de185899418a4f96901add 891 Gene3D G3DSA:3.40.50.970 472 705 1.5E-67 T 28-03-2018 A6A12_RS02650 b32e55bc05de185899418a4f96901add 891 Gene3D G3DSA:3.40.50.970 55 471 1.8E-83 T 28-03-2018 A6A12_RS02650 b32e55bc05de185899418a4f96901add 891 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 4 890 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A6A12_RS02650 b32e55bc05de185899418a4f96901add 891 Gene3D G3DSA:3.40.50.920 706 891 1.9E-35 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A6A12_RS02650 b32e55bc05de185899418a4f96901add 891 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 104 298 3.2E-10 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A6A12_RS02650 b32e55bc05de185899418a4f96901add 891 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 360 432 7.7E-5 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A6A12_RS02650 b32e55bc05de185899418a4f96901add 891 SUPERFAMILY SSF52518 475 699 6.83E-98 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS02650 b32e55bc05de185899418a4f96901add 891 SUPERFAMILY SSF52922 701 890 8.16E-56 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A6A12_RS02650 b32e55bc05de185899418a4f96901add 891 PIRSF PIRSF000156 1 891 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 A6A12_RS02650 b32e55bc05de185899418a4f96901add 891 SUPERFAMILY SSF52518 56 469 3.17E-139 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS04660 6ef35baab3da479feb34993391d24bc0 195 Gene3D G3DSA:3.30.70.20 25 121 3.4E-10 T 28-03-2018 A6A12_RS04660 6ef35baab3da479feb34993391d24bc0 195 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 114 125 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A6A12_RS04660 6ef35baab3da479feb34993391d24bc0 195 SUPERFAMILY SSF54862 37 173 1.86E-30 T 28-03-2018 A6A12_RS04660 6ef35baab3da479feb34993391d24bc0 195 Gene3D G3DSA:3.30.70.20 148 182 1.2E-5 T 28-03-2018 A6A12_RS04660 6ef35baab3da479feb34993391d24bc0 195 Hamap MF_00463 Electron transport complex subunit RsxB [rsxB]. 4 182 42.635 T 28-03-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 A6A12_RS04660 6ef35baab3da479feb34993391d24bc0 195 Gene3D G3DSA:3.30.70.20 122 147 5.3E-11 T 28-03-2018 A6A12_RS04660 6ef35baab3da479feb34993391d24bc0 195 Pfam PF04060 Putative Fe-S cluster 44 75 2.1E-14 T 28-03-2018 IPR007202 4Fe-4S domain GO:0051536 A6A12_RS04660 6ef35baab3da479feb34993391d24bc0 195 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 1 186 2.3E-86 T 28-03-2018 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 A6A12_RS04660 6ef35baab3da479feb34993391d24bc0 195 PIRSF PIRSF005784 3 188 6.9E-87 T 28-03-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 A6A12_RS04660 6ef35baab3da479feb34993391d24bc0 195 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 144 155 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A6A12_RS04660 6ef35baab3da479feb34993391d24bc0 195 Pfam PF14697 4Fe-4S dicluster domain 107 161 1.6E-17 T 28-03-2018 A6A12_RS03645 4b7384556ef71ed9c4deb179c3ac4514 634 Pfam PF05043 Mga helix-turn-helix domain 97 161 1.9E-6 T 28-03-2018 IPR007737 Mga helix-turn-helix domain A6A12_RS03645 4b7384556ef71ed9c4deb179c3ac4514 634 SUPERFAMILY SSF46785 6 65 2.72E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03645 4b7384556ef71ed9c4deb179c3ac4514 634 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 506 625 6.0E-15 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A6A12_RS03645 4b7384556ef71ed9c4deb179c3ac4514 634 Gene3D G3DSA:1.10.10.10 87 153 2.5E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03645 4b7384556ef71ed9c4deb179c3ac4514 634 Gene3D G3DSA:1.10.10.10 1 69 1.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03645 4b7384556ef71ed9c4deb179c3ac4514 634 Pfam PF08279 HTH domain 19 64 1.1E-8 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A6A12_RS03645 4b7384556ef71ed9c4deb179c3ac4514 634 Gene3D G3DSA:3.40.930.10 490 632 3.7E-18 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A6A12_RS03645 4b7384556ef71ed9c4deb179c3ac4514 634 SUPERFAMILY SSF55804 493 627 5.62E-20 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A6A12_RS03645 4b7384556ef71ed9c4deb179c3ac4514 634 SUPERFAMILY SSF63520 290 392 6.67E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 A6A12_RS03645 4b7384556ef71ed9c4deb179c3ac4514 634 Gene3D G3DSA:1.10.1790.10 277 392 5.9E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 A6A12_RS03645 4b7384556ef71ed9c4deb179c3ac4514 634 Gene3D G3DSA:3.40.50.2300 397 483 1.6E-9 T 28-03-2018 A6A12_RS03645 4b7384556ef71ed9c4deb179c3ac4514 634 Pfam PF00874 PRD domain 300 386 4.8E-13 T 28-03-2018 IPR011608 PRD domain GO:0006355 A6A12_RS03295 5e810269c249084ac58376963abe3927 348 SUPERFAMILY SSF53850 24 340 4.35E-56 T 28-03-2018 A6A12_RS03295 5e810269c249084ac58376963abe3927 348 Pfam PF13416 Bacterial extracellular solute-binding protein 38 303 2.0E-22 T 28-03-2018 A6A12_RS03295 5e810269c249084ac58376963abe3927 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 288 314 9.7E-13 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS03295 5e810269c249084ac58376963abe3927 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 28 44 9.7E-13 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS03295 5e810269c249084ac58376963abe3927 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 113 129 9.7E-13 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS03295 5e810269c249084ac58376963abe3927 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 243 262 9.7E-13 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS03295 5e810269c249084ac58376963abe3927 348 Gene3D G3DSA:3.40.190.10 138 282 2.1E-26 T 28-03-2018 A6A12_RS03295 5e810269c249084ac58376963abe3927 348 Gene3D G3DSA:3.40.190.10 21 137 9.0E-10 T 28-03-2018 A6A12_RS05255 125c09a6ed2efd6b232693627abfadd8 324 Gene3D G3DSA:3.40.190.10 92 183 2.3E-21 T 28-03-2018 A6A12_RS05255 125c09a6ed2efd6b232693627abfadd8 324 Gene3D G3DSA:3.40.190.10 184 263 5.8E-19 T 28-03-2018 A6A12_RS05255 125c09a6ed2efd6b232693627abfadd8 324 SUPERFAMILY SSF46785 1 87 1.25E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05255 125c09a6ed2efd6b232693627abfadd8 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 2.2E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS05255 125c09a6ed2efd6b232693627abfadd8 324 Pfam PF03466 LysR substrate binding domain 91 292 9.9E-39 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS05255 125c09a6ed2efd6b232693627abfadd8 324 SUPERFAMILY SSF53850 91 322 2.53E-40 T 28-03-2018 A6A12_RS05255 125c09a6ed2efd6b232693627abfadd8 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.8E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS05255 125c09a6ed2efd6b232693627abfadd8 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.8E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS05255 125c09a6ed2efd6b232693627abfadd8 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.8E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS05255 125c09a6ed2efd6b232693627abfadd8 324 Gene3D G3DSA:1.10.10.10 1 85 3.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS04420 3250e23d50afcc0b2d9bd42ec7a18248 474 Gene3D G3DSA:3.80.30.20 144 381 5.9E-52 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe A6A12_RS04420 3250e23d50afcc0b2d9bd42ec7a18248 474 SUPERFAMILY SSF102114 121 374 1.96E-61 T 28-03-2018 A6A12_RS04420 3250e23d50afcc0b2d9bd42ec7a18248 474 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 3 440 72.535 T 28-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 A6A12_RS04420 3250e23d50afcc0b2d9bd42ec7a18248 474 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 437 2.3E-150 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A6A12_RS04420 3250e23d50afcc0b2d9bd42ec7a18248 474 Pfam PF00919 Uncharacterized protein family UPF0004 4 104 1.2E-29 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A6A12_RS04420 3250e23d50afcc0b2d9bd42ec7a18248 474 Pfam PF01938 TRAM domain 379 440 4.2E-17 T 28-03-2018 IPR002792 TRAM domain A6A12_RS04420 3250e23d50afcc0b2d9bd42ec7a18248 474 SMART SM00729 147 367 5.3E-63 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A6A12_RS04420 3250e23d50afcc0b2d9bd42ec7a18248 474 Pfam PF04055 Radical SAM superfamily 151 325 1.3E-27 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A6A12_RS04420 3250e23d50afcc0b2d9bd42ec7a18248 474 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 151 171 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A6A12_RS04420 3250e23d50afcc0b2d9bd42ec7a18248 474 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 440 3.4E-196 T 28-03-2018 A6A12_RS04535 e209adc36fe00c463651eecc7ccf9045 321 TIGRFAM TIGR00109 hemH: ferrochelatase 7 320 1.7E-101 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A6A12_RS04535 e209adc36fe00c463651eecc7ccf9045 321 SUPERFAMILY SSF53800 8 320 6.62E-99 T 28-03-2018 A6A12_RS04535 e209adc36fe00c463651eecc7ccf9045 321 Gene3D G3DSA:3.40.50.1400 4 175 1.8E-45 T 28-03-2018 A6A12_RS04535 e209adc36fe00c463651eecc7ccf9045 321 Pfam PF00762 Ferrochelatase 9 320 1.6E-105 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A6A12_RS04535 e209adc36fe00c463651eecc7ccf9045 321 Hamap MF_00323 Ferrochelatase [hemH]. 8 321 35.708 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A6A12_RS04535 e209adc36fe00c463651eecc7ccf9045 321 Gene3D G3DSA:3.40.50.1400 176 304 8.3E-40 T 28-03-2018 A6A12_RS04535 e209adc36fe00c463651eecc7ccf9045 321 ProSitePatterns PS00534 Ferrochelatase signature. 192 210 - T 28-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 652 695 6.0E-18 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 7 839 0.0 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 SUPERFAMILY SSF50447 454 551 4.24E-17 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 860 198.283 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 Gene3D G3DSA:3.30.930.10 2 251 4.1E-116 T 28-03-2018 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 Pfam PF02272 DHHA1 domain 718 856 4.3E-29 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 SMART SM00863 652 695 2.3E-21 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 PRINTS PR00980 Alanyl-tRNA synthetase signature 281 297 4.8E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 PRINTS PR00980 Alanyl-tRNA synthetase signature 76 87 4.8E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 PRINTS PR00980 Alanyl-tRNA synthetase signature 208 219 4.8E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 PRINTS PR00980 Alanyl-tRNA synthetase signature 235 248 4.8E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 PRINTS PR00980 Alanyl-tRNA synthetase signature 305 318 4.8E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 Pfam PF01411 tRNA synthetases class II (A) 7 555 3.4E-223 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 SUPERFAMILY SSF55186 551 711 8.11E-52 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 SUPERFAMILY SSF55681 3 254 7.21E-108 T 28-03-2018 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 Gene3D G3DSA:3.30.980.10 552 698 1.9E-45 T 28-03-2018 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 Gene3D G3DSA:1.20.120.330 699 813 8.4E-4 T 28-03-2018 A6A12_RS02465 4cd633177e5c30c8b32b7308d0eff5b8 860 SUPERFAMILY SSF101353 255 461 2.62E-59 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A6A12_RS09255 f303e505d890b5aa3aaf1818cac59a93 306 Pfam PF13737 Transposase DDE domain 19 129 2.3E-45 T 28-03-2018 IPR025668 Transposase DDE domain A6A12_RS09255 f303e505d890b5aa3aaf1818cac59a93 306 Gene3D G3DSA:3.30.420.10 101 191 0.0026 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS06030 f303e505d890b5aa3aaf1818cac59a93 306 Pfam PF13737 Transposase DDE domain 19 129 2.3E-45 T 28-03-2018 IPR025668 Transposase DDE domain A6A12_RS06030 f303e505d890b5aa3aaf1818cac59a93 306 Gene3D G3DSA:3.30.420.10 101 191 0.0026 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS00515 f303e505d890b5aa3aaf1818cac59a93 306 Pfam PF13737 Transposase DDE domain 19 129 2.3E-45 T 28-03-2018 IPR025668 Transposase DDE domain A6A12_RS00515 f303e505d890b5aa3aaf1818cac59a93 306 Gene3D G3DSA:3.30.420.10 101 191 0.0026 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS13820 f303e505d890b5aa3aaf1818cac59a93 306 Pfam PF13737 Transposase DDE domain 19 129 2.3E-45 T 28-03-2018 IPR025668 Transposase DDE domain A6A12_RS13820 f303e505d890b5aa3aaf1818cac59a93 306 Gene3D G3DSA:3.30.420.10 101 191 0.0026 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS07035 f303e505d890b5aa3aaf1818cac59a93 306 Pfam PF13737 Transposase DDE domain 19 129 2.3E-45 T 28-03-2018 IPR025668 Transposase DDE domain A6A12_RS07035 f303e505d890b5aa3aaf1818cac59a93 306 Gene3D G3DSA:3.30.420.10 101 191 0.0026 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS13700 f303e505d890b5aa3aaf1818cac59a93 306 Pfam PF13737 Transposase DDE domain 19 129 2.3E-45 T 28-03-2018 IPR025668 Transposase DDE domain A6A12_RS13700 f303e505d890b5aa3aaf1818cac59a93 306 Gene3D G3DSA:3.30.420.10 101 191 0.0026 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS03695 f303e505d890b5aa3aaf1818cac59a93 306 Pfam PF13737 Transposase DDE domain 19 129 2.3E-45 T 28-03-2018 IPR025668 Transposase DDE domain A6A12_RS03695 f303e505d890b5aa3aaf1818cac59a93 306 Gene3D G3DSA:3.30.420.10 101 191 0.0026 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS14210 f303e505d890b5aa3aaf1818cac59a93 306 Pfam PF13737 Transposase DDE domain 19 129 2.3E-45 T 28-03-2018 IPR025668 Transposase DDE domain A6A12_RS14210 f303e505d890b5aa3aaf1818cac59a93 306 Gene3D G3DSA:3.30.420.10 101 191 0.0026 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS04610 65f52f44d796e721f4934480794c2857 504 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 463 3.2E-164 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A6A12_RS04610 65f52f44d796e721f4934480794c2857 504 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 463 45.056 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A6A12_RS04610 65f52f44d796e721f4934480794c2857 504 Pfam PF00156 Phosphoribosyl transferase domain 280 388 3.7E-6 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A6A12_RS04610 65f52f44d796e721f4934480794c2857 504 Gene3D G3DSA:3.60.20.10 2 256 2.9E-55 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A6A12_RS04610 65f52f44d796e721f4934480794c2857 504 SUPERFAMILY SSF53271 249 482 2.75E-70 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A6A12_RS04610 65f52f44d796e721f4934480794c2857 504 Gene3D G3DSA:3.40.50.2020 274 443 1.7E-37 T 28-03-2018 A6A12_RS04610 65f52f44d796e721f4934480794c2857 504 SUPERFAMILY SSF56235 2 256 1.46E-70 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A6A12_RS04610 65f52f44d796e721f4934480794c2857 504 Pfam PF13522 Glutamine amidotransferase domain 63 194 1.0E-16 T 28-03-2018 A6A12_RS04610 65f52f44d796e721f4934480794c2857 504 PIRSF PIRSF000485 1 480 1.6E-169 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A6A12_RS12195 54615418da40dba720ec7785c25737fc 178 Gene3D G3DSA:1.10.60.30 106 177 1.2E-25 T 28-03-2018 A6A12_RS12195 54615418da40dba720ec7785c25737fc 178 Pfam PF04751 Protein of unknown function (DUF615) 21 171 2.2E-56 T 28-03-2018 IPR006839 Ribosome-associated, YjgA A6A12_RS12195 54615418da40dba720ec7785c25737fc 178 Hamap MF_00765 UPF0307 protein YjgA [yjgA]. 11 175 23.189 T 28-03-2018 IPR006839 Ribosome-associated, YjgA A6A12_RS12195 54615418da40dba720ec7785c25737fc 178 Gene3D G3DSA:1.10.60.30 33 101 1.9E-28 T 28-03-2018 A6A12_RS12195 54615418da40dba720ec7785c25737fc 178 PIRSF PIRSF016183 3 177 1.6E-71 T 28-03-2018 IPR006839 Ribosome-associated, YjgA A6A12_RS12195 54615418da40dba720ec7785c25737fc 178 SUPERFAMILY SSF158710 31 173 4.05E-52 T 28-03-2018 IPR023153 PSPTO4464-like domain A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 SUPERFAMILY SSF48179 496 639 2.3E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 Hamap MF_01621 Fatty acid oxidation complex subunit alpha [fadB]. 1 716 52.059 T 28-03-2018 IPR012799 Fatty oxidation complex, alpha subunit FadB GO:0003857|GO:0004165|GO:0004300|GO:0008692|GO:0009062|GO:0036125|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35+5.3.3.8|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5137|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6837|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-7291|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 TIGRFAM TIGR02437 FadB: fatty oxidation complex, alpha subunit FadB 1 715 0.0 T 28-03-2018 IPR012799 Fatty oxidation complex, alpha subunit FadB GO:0003857|GO:0004165|GO:0004300|GO:0008692|GO:0009062|GO:0036125|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35+5.3.3.8|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5137|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6837|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-7291|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 Gene3D G3DSA:1.10.1040.10 623 719 1.9E-17 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 SUPERFAMILY SSF52096 2 304 3.02E-65 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 Gene3D G3DSA:3.90.226.10 2 206 8.0E-52 T 28-03-2018 A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 494 518 - T 28-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 628 712 3.0E-5 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 497 593 2.5E-25 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 317 495 6.4E-59 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 Gene3D G3DSA:1.10.1040.10 504 593 2.5E-22 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 SUPERFAMILY SSF51735 315 496 1.18E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 SUPERFAMILY SSF48179 625 715 2.72E-24 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 207 6.5E-40 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A6A12_RS14320 eec1afe44193f651099b1fd49935f483 723 Gene3D G3DSA:3.40.50.720 256 496 3.2E-59 T 28-03-2018 A6A12_RS02700 7a48679ecd7a4d4335b705616fb8eefa 293 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 280 2.0E-107 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A6A12_RS02700 7a48679ecd7a4d4335b705616fb8eefa 293 Gene3D G3DSA:3.40.50.620 1 176 7.4E-79 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS02700 7a48679ecd7a4d4335b705616fb8eefa 293 Hamap MF_00158 Pantothenate synthetase [panC]. 2 280 40.018 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A6A12_RS02700 7a48679ecd7a4d4335b705616fb8eefa 293 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 23 62 1.4E-8 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A6A12_RS02700 7a48679ecd7a4d4335b705616fb8eefa 293 Pfam PF02569 Pantoate-beta-alanine ligase 3 278 6.3E-102 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 A6A12_RS02700 7a48679ecd7a4d4335b705616fb8eefa 293 Gene3D G3DSA:3.30.1300.10 177 293 5.2E-30 T 28-03-2018 A6A12_RS02700 7a48679ecd7a4d4335b705616fb8eefa 293 SUPERFAMILY SSF52374 1 280 3.94E-107 T 28-03-2018 A6A12_RS01870 737c0dbd52f72c4ed9bfa2d46612638b 376 Pfam PF01464 Transglycosylase SLT domain 212 335 1.3E-29 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 A6A12_RS01870 737c0dbd52f72c4ed9bfa2d46612638b 376 Gene3D G3DSA:1.10.530.10 189 372 2.0E-35 T 28-03-2018 A6A12_RS01870 737c0dbd52f72c4ed9bfa2d46612638b 376 Pfam PF11873 Domain of unknown function (DUF3393) 4 206 3.2E-78 T 28-03-2018 IPR024570 Murein transglycosylase-C, N-terminal A6A12_RS01870 737c0dbd52f72c4ed9bfa2d46612638b 376 SUPERFAMILY SSF53955 188 370 6.76E-37 T 28-03-2018 IPR023346 Lysozyme-like domain A6A12_RS01870 737c0dbd52f72c4ed9bfa2d46612638b 376 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 228 256 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 A6A12_RS09360 9a5709b384f9d4b0f110025cfbb19ab7 458 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 16 457 1.2E-106 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A6A12_RS09360 9a5709b384f9d4b0f110025cfbb19ab7 458 Gene3D G3DSA:3.40.50.720 256 449 0.001 T 28-03-2018 A6A12_RS09360 9a5709b384f9d4b0f110025cfbb19ab7 458 PIRSF PIRSF002746 8 458 3.6E-147 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A6A12_RS09360 9a5709b384f9d4b0f110025cfbb19ab7 458 Pfam PF02447 GntP family permease 14 456 5.1E-119 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A6A12_RS14160 6125d3c7054eecb4d9a5eefedf14a36a 395 Gene3D G3DSA:2.40.30.10 198 270 7.4E-23 T 28-03-2018 A6A12_RS14160 6125d3c7054eecb4d9a5eefedf14a36a 395 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.8E-5 T 28-03-2018 A6A12_RS14160 6125d3c7054eecb4d9a5eefedf14a36a 395 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 348 370 4.8E-5 T 28-03-2018 A6A12_RS14160 6125d3c7054eecb4d9a5eefedf14a36a 395 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 4.8E-5 T 28-03-2018 A6A12_RS14160 6125d3c7054eecb4d9a5eefedf14a36a 395 SUPERFAMILY SSF160996 191 339 2.09E-42 T 28-03-2018 A6A12_RS14160 6125d3c7054eecb4d9a5eefedf14a36a 395 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 7 393 9.2E-130 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like A6A12_RS14160 6125d3c7054eecb4d9a5eefedf14a36a 395 Pfam PF03486 HI0933-like protein 5 393 3.8E-156 T 28-03-2018 A6A12_RS14160 6125d3c7054eecb4d9a5eefedf14a36a 395 Gene3D G3DSA:1.10.8.260 271 323 5.6E-15 T 28-03-2018 IPR023166 HI0933 insert-like domain A6A12_RS14160 6125d3c7054eecb4d9a5eefedf14a36a 395 SUPERFAMILY SSF51905 1 189 1.59E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS14160 6125d3c7054eecb4d9a5eefedf14a36a 395 SUPERFAMILY SSF51905 338 395 1.59E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS14160 6125d3c7054eecb4d9a5eefedf14a36a 395 Gene3D G3DSA:3.50.50.60 1 197 1.7E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS14160 6125d3c7054eecb4d9a5eefedf14a36a 395 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 5.7E-8 T 28-03-2018 A6A12_RS14160 6125d3c7054eecb4d9a5eefedf14a36a 395 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 165 5.7E-8 T 28-03-2018 A6A12_RS14160 6125d3c7054eecb4d9a5eefedf14a36a 395 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 363 370 5.7E-8 T 28-03-2018 A6A12_RS04885 5ebe9d21f1ce2e957ab1f6b905e335db 291 Gene3D G3DSA:3.40.190.10 175 260 8.1E-21 T 28-03-2018 A6A12_RS04885 5ebe9d21f1ce2e957ab1f6b905e335db 291 SUPERFAMILY SSF53850 88 288 3.57E-38 T 28-03-2018 A6A12_RS04885 5ebe9d21f1ce2e957ab1f6b905e335db 291 Pfam PF03466 LysR substrate binding domain 88 286 1.8E-40 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS04885 5ebe9d21f1ce2e957ab1f6b905e335db 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.2E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS04885 5ebe9d21f1ce2e957ab1f6b905e335db 291 Gene3D G3DSA:3.40.190.10 89 174 9.0E-14 T 28-03-2018 A6A12_RS04885 5ebe9d21f1ce2e957ab1f6b905e335db 291 SUPERFAMILY SSF46785 1 83 6.51E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS04885 5ebe9d21f1ce2e957ab1f6b905e335db 291 Gene3D G3DSA:1.10.10.10 1 88 2.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS12560 d20604e43bc0fe893d4d41a21201f5d9 190 Gene3D G3DSA:3.40.50.360 2 183 1.4E-34 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS12560 d20604e43bc0fe893d4d41a21201f5d9 190 Pfam PF02525 Flavodoxin-like fold 8 172 1.5E-44 T 28-03-2018 IPR003680 Flavodoxin-like fold A6A12_RS12560 d20604e43bc0fe893d4d41a21201f5d9 190 SUPERFAMILY SSF52218 7 178 1.95E-48 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS12560 d20604e43bc0fe893d4d41a21201f5d9 190 Hamap MF_01415 Glutathione-regulated potassium-efflux system ancillary protein KefG [kefG]. 3 187 48.545 T 28-03-2018 IPR023947 Glutathione-regulated potassium-efflux system ancillary protein KefG GO:0006813 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 A6A12_RS03305 23a36b59a885705a291ffea267e1beba 108 SUPERFAMILY SSF69754 1 103 7.85E-30 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A6A12_RS03305 23a36b59a885705a291ffea267e1beba 108 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 92 1.5E-22 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A6A12_RS03305 23a36b59a885705a291ffea267e1beba 108 Gene3D G3DSA:3.30.160.100 1 100 9.2E-28 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A6A12_RS03305 23a36b59a885705a291ffea267e1beba 108 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 100 1.4E-30 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A6A12_RS10510 789e221e625aace157d5466c7c36a03c 127 Pfam PF04247 Invasion gene expression up-regulator, SirB 2 122 1.6E-38 T 28-03-2018 IPR007360 Invasion gene expression up-regulator, SirB A6A12_RS10510 789e221e625aace157d5466c7c36a03c 127 PIRSF PIRSF005610 1 121 5.1E-18 T 28-03-2018 IPR007360 Invasion gene expression up-regulator, SirB A6A12_RS04890 d426db8f1ca3dcc99d5d3ef9273bf6c3 372 SMART SM00448 25 136 5.0E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS04890 d426db8f1ca3dcc99d5d3ef9273bf6c3 372 SUPERFAMILY SSF52172 25 143 1.42E-31 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS04890 d426db8f1ca3dcc99d5d3ef9273bf6c3 372 Pfam PF00072 Response regulator receiver domain 27 131 1.9E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS04890 d426db8f1ca3dcc99d5d3ef9273bf6c3 372 Gene3D G3DSA:3.40.50.2300 20 326 6.3E-34 T 28-03-2018 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 PIRSF PIRSF000207 13 617 4.4E-267 T 28-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 Gene3D G3DSA:3.40.50.360 52 237 6.1E-42 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 SUPERFAMILY SSF52218 80 227 2.37E-47 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 Gene3D G3DSA:2.40.30.10 238 456 7.8E-47 T 28-03-2018 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 Pfam PF00667 FAD binding domain 250 441 2.8E-27 T 28-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 Hamap MF_01541 Sulfite reductase [NADPH] flavoprotein alpha-component [cysJ]. 14 617 48.187 T 28-03-2018 IPR029758 Sulphite reductase [NADPH] flavoprotein, alpha chain, Proteobacteria GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 Pfam PF00258 Flavodoxin 84 208 1.4E-29 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 SUPERFAMILY SSF52343 462 617 4.45E-51 T 28-03-2018 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 22 617 7.9E-252 T 28-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 543 559 1.2E-27 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 437 446 1.2E-27 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 404 411 1.2E-27 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 499 508 1.2E-27 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 288 298 1.2E-27 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 566 574 1.2E-27 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 512 523 1.2E-27 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 474 493 1.2E-27 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 Pfam PF00175 Oxidoreductase NAD-binding domain 475 581 2.5E-17 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 Gene3D G3DSA:3.40.50.80 471 617 8.5E-37 T 28-03-2018 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 SUPERFAMILY SSF63380 246 463 1.53E-63 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 PRINTS PR00369 Flavodoxin signature 131 142 1.9E-12 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 PRINTS PR00369 Flavodoxin signature 187 206 1.9E-12 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 PRINTS PR00369 Flavodoxin signature 83 96 1.9E-12 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A6A12_RS01465 1eff553aed15410386e26499963bc77c 617 PRINTS PR00369 Flavodoxin signature 163 173 1.9E-12 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 A6A12_RS10900 b7fd97bf0aa20a59f5a71a0326543ac1 243 Pfam PF00696 Amino acid kinase family 11 219 4.6E-26 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS10900 b7fd97bf0aa20a59f5a71a0326543ac1 243 Hamap MF_01220_B Uridylate kinase [pyrH]. 7 240 43.709 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A6A12_RS10900 b7fd97bf0aa20a59f5a71a0326543ac1 243 PIRSF PIRSF005650 4 243 5.9E-89 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A6A12_RS10900 b7fd97bf0aa20a59f5a71a0326543ac1 243 Gene3D G3DSA:3.40.1160.10 2 241 4.9E-43 T 28-03-2018 A6A12_RS10900 b7fd97bf0aa20a59f5a71a0326543ac1 243 SUPERFAMILY SSF53633 7 240 5.76E-71 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS10900 b7fd97bf0aa20a59f5a71a0326543ac1 243 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 9 240 5.3E-102 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 A6A12_RS11060 7f320a774b17f3fb8a633e78e2625996 210 Hamap MF_00428 Na(+)-translocating NADH-quinone reductase subunit D [nqrD]. 2 207 36.946 T 28-03-2018 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 A6A12_RS11060 7f320a774b17f3fb8a633e78e2625996 210 TIGRFAM TIGR01939 nqrD: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit 3 206 1.0E-108 T 28-03-2018 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 A6A12_RS11060 7f320a774b17f3fb8a633e78e2625996 210 Pfam PF02508 Rnf-Nqr subunit, membrane protein 9 195 1.2E-62 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 A6A12_RS11060 7f320a774b17f3fb8a633e78e2625996 210 PIRSF PIRSF006102 3 210 1.1E-72 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 A6A12_RS14450 1a8db145669371a1828da567a6d4e83e 249 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 25 243 2.8E-54 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS14450 1a8db145669371a1828da567a6d4e83e 249 SMART SM00062 24 245 1.1E-72 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS14450 1a8db145669371a1828da567a6d4e83e 249 Gene3D G3DSA:3.40.190.10 15 123 2.0E-27 T 28-03-2018 A6A12_RS14450 1a8db145669371a1828da567a6d4e83e 249 SUPERFAMILY SSF53850 1 246 2.55E-55 T 28-03-2018 A6A12_RS14450 1a8db145669371a1828da567a6d4e83e 249 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 46 59 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 A6A12_RS14450 1a8db145669371a1828da567a6d4e83e 249 Gene3D G3DSA:3.40.190.10 124 203 3.8E-17 T 28-03-2018 A6A12_RS03445 2eeefff12d3927a4e904b568cd9cf1cb 544 PIRSF PIRSF001363 12 544 1.9E-249 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A6A12_RS03445 2eeefff12d3927a4e904b568cd9cf1cb 544 Gene3D G3DSA:3.20.20.360 92 426 2.3E-106 T 28-03-2018 A6A12_RS03445 2eeefff12d3927a4e904b568cd9cf1cb 544 Gene3D G3DSA:1.20.1220.12 427 543 4.6E-47 T 28-03-2018 A6A12_RS03445 2eeefff12d3927a4e904b568cd9cf1cb 544 ProSitePatterns PS00510 Malate synthase signature. 277 292 - T 28-03-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A6A12_RS03445 2eeefff12d3927a4e904b568cd9cf1cb 544 Pfam PF01274 Malate synthase 23 543 4.6E-198 T 28-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A6A12_RS03445 2eeefff12d3927a4e904b568cd9cf1cb 544 SUPERFAMILY SSF51645 12 543 1.96E-187 T 28-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A6A12_RS03445 2eeefff12d3927a4e904b568cd9cf1cb 544 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 34 543 2.6E-260 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 A6A12_RS03835 321fb01926086d264396dd341bfc3b78 584 Gene3D G3DSA:3.40.50.300 1 463 1.7E-26 T 28-03-2018 A6A12_RS03835 321fb01926086d264396dd341bfc3b78 584 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 309 431 3.3E-16 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A6A12_RS03835 321fb01926086d264396dd341bfc3b78 584 SMART SM00382 32 449 7.2E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS03835 321fb01926086d264396dd341bfc3b78 584 Pfam PF13175 AAA ATPase domain 19 94 1.5E-9 T 28-03-2018 A6A12_RS03835 321fb01926086d264396dd341bfc3b78 584 SUPERFAMILY SSF52540 18 146 1.86E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03835 321fb01926086d264396dd341bfc3b78 584 SUPERFAMILY SSF52540 307 447 1.86E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09210 8df57a459ed2a79751e88cecebb29103 300 Gene3D G3DSA:1.10.3720.10 38 300 6.1E-42 T 28-03-2018 A6A12_RS09210 8df57a459ed2a79751e88cecebb29103 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 298 9.5E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS09210 8df57a459ed2a79751e88cecebb29103 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 24 69 1.9E-13 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A6A12_RS09210 8df57a459ed2a79751e88cecebb29103 300 SUPERFAMILY SSF161098 96 281 7.98E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS11720 3ca0b6e10d4a22e5f432ade500f5416d 226 SUPERFAMILY SSF109755 28 216 1.12E-15 T 28-03-2018 A6A12_RS11720 3ca0b6e10d4a22e5f432ade500f5416d 226 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 4 225 5.8E-67 T 28-03-2018 IPR002727 Protein of unknown function DUF47 A6A12_RS11720 3ca0b6e10d4a22e5f432ade500f5416d 226 Pfam PF01865 Protein of unknown function DUF47 7 223 1.1E-64 T 28-03-2018 IPR018445 Putative phosphate transport regulator A6A12_RS11720 3ca0b6e10d4a22e5f432ade500f5416d 226 Gene3D G3DSA:1.20.58.220 114 226 2.2E-7 T 28-03-2018 A6A12_RS07810 580b426a45e5e603781c42b169d1ab0c 138 Gene3D G3DSA:3.10.450.40 8 127 1.6E-9 T 28-03-2018 A6A12_RS07810 580b426a45e5e603781c42b169d1ab0c 138 Pfam PF04965 Gene 25-like lysozyme 17 110 1.9E-7 T 28-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD A6A12_RS07810 580b426a45e5e603781c42b169d1ab0c 138 SUPERFAMILY SSF160719 60 111 4.05E-5 T 28-03-2018 A6A12_RS07810 580b426a45e5e603781c42b169d1ab0c 138 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 12 132 5.7E-17 T 28-03-2018 IPR017737 Type VI secretion system, lysozyme-related protein A6A12_RS08755 56ad2a6ffb95462c0c24f6bbf69de2aa 193 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 6 178 1.7E-44 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 A6A12_RS08755 56ad2a6ffb95462c0c24f6bbf69de2aa 193 Pfam PF03695 Uncharacterised protein family (UPF0149) 7 182 2.6E-38 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 A6A12_RS08755 56ad2a6ffb95462c0c24f6bbf69de2aa 193 SUPERFAMILY SSF101327 6 180 1.31E-30 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 A6A12_RS12425 55a0280aac08196be10a11f665b84754 117 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 117 3.0E-43 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12425 55a0280aac08196be10a11f665b84754 117 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 117 25.726 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12425 55a0280aac08196be10a11f665b84754 117 Gene3D G3DSA:3.30.420.100 1 117 4.2E-37 T 28-03-2018 A6A12_RS12425 55a0280aac08196be10a11f665b84754 117 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 117 3.0E-43 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12425 55a0280aac08196be10a11f665b84754 117 SUPERFAMILY SSF53137 3 115 1.29E-50 T 28-03-2018 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 332 764 1.2E-105 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 Gene3D G3DSA:3.20.20.80 330 817 2.3E-119 T 28-03-2018 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 Gene3D G3DSA:2.60.40.10 818 882 2.8E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 ProSitePatterns PS00018 EF-hand calcium-binding domain. 711 723 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 SUPERFAMILY SSF81296 780 882 1.02E-36 T 28-03-2018 IPR014756 Immunoglobulin E-set A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 Gene3D G3DSA:3.30.379.10 204 329 4.3E-18 T 28-03-2018 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 SMART SM01081 34 195 1.2E-88 T 28-03-2018 IPR004866 Chitobiase/beta-hexosaminidases, N-terminal domain KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 Pfam PF03174 Chitobiase/beta-hexosaminidase C-terminal domain 804 879 1.0E-27 T 28-03-2018 IPR004867 Chitobiase C-terminal domain KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 211 329 7.9E-14 T 28-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 Gene3D G3DSA:2.60.40.290 25 167 4.9E-35 T 28-03-2018 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 Pfam PF03173 Putative carbohydrate binding domain 35 193 1.8E-61 T 28-03-2018 IPR004866 Chitobiase/beta-hexosaminidases, N-terminal domain KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 SUPERFAMILY SSF51445 332 772 1.26E-138 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 SUPERFAMILY SSF55545 207 331 6.41E-24 T 28-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 SUPERFAMILY SSF49384 26 198 8.37E-64 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 PRINTS PR00738 Glycosyl hydrolase family 20 signature 355 376 5.0E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 PRINTS PR00738 Glycosyl hydrolase family 20 signature 432 449 5.0E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 PRINTS PR00738 Glycosyl hydrolase family 20 signature 499 517 5.0E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 PRINTS PR00738 Glycosyl hydrolase family 20 signature 746 763 5.0E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 PRINTS PR00738 Glycosyl hydrolase family 20 signature 526 539 5.0E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 PRINTS PR00738 Glycosyl hydrolase family 20 signature 728 744 5.0E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 PRINTS PR00738 Glycosyl hydrolase family 20 signature 292 312 5.0E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS10725 8209268ae1180e89076b97a3723425df 883 PRINTS PR00738 Glycosyl hydrolase family 20 signature 326 343 5.0E-47 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS03480 4ea7ac5471c31805b3b93dbf2d274209 315 Gene3D G3DSA:1.20.1640.10 77 299 3.4E-30 T 28-03-2018 A6A12_RS03480 4ea7ac5471c31805b3b93dbf2d274209 315 PRINTS PR01755 Bacterial translocase SecF protein signature 233 248 3.5E-32 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A6A12_RS03480 4ea7ac5471c31805b3b93dbf2d274209 315 PRINTS PR01755 Bacterial translocase SecF protein signature 38 53 3.5E-32 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A6A12_RS03480 4ea7ac5471c31805b3b93dbf2d274209 315 PRINTS PR01755 Bacterial translocase SecF protein signature 201 219 3.5E-32 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A6A12_RS03480 4ea7ac5471c31805b3b93dbf2d274209 315 PRINTS PR01755 Bacterial translocase SecF protein signature 153 167 3.5E-32 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A6A12_RS03480 4ea7ac5471c31805b3b93dbf2d274209 315 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 39 285 4.2E-86 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A6A12_RS03480 4ea7ac5471c31805b3b93dbf2d274209 315 SUPERFAMILY SSF82866 74 293 1.31E-39 T 28-03-2018 A6A12_RS03480 4ea7ac5471c31805b3b93dbf2d274209 315 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 109 282 6.4E-56 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A6A12_RS03480 4ea7ac5471c31805b3b93dbf2d274209 315 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 11 296 29.124 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 A6A12_RS03480 4ea7ac5471c31805b3b93dbf2d274209 315 Pfam PF07549 SecD/SecF GG Motif 35 60 5.5E-10 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A6A12_RS03480 4ea7ac5471c31805b3b93dbf2d274209 315 Pfam PF02355 Protein export membrane protein 111 292 3.3E-71 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A6A12_RS14355 66d9405b7d2ce2364a1e069a12eb0474 288 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 288 36.991 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14355 66d9405b7d2ce2364a1e069a12eb0474 288 Gene3D G3DSA:3.40.1380.10 42 239 4.0E-75 T 28-03-2018 A6A12_RS14355 66d9405b7d2ce2364a1e069a12eb0474 288 Pfam PF00231 ATP synthase 5 287 2.7E-98 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14355 66d9405b7d2ce2364a1e069a12eb0474 288 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 5.9E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14355 66d9405b7d2ce2364a1e069a12eb0474 288 PRINTS PR00126 ATP synthase gamma subunit signature 235 254 5.9E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14355 66d9405b7d2ce2364a1e069a12eb0474 288 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 5.9E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14355 66d9405b7d2ce2364a1e069a12eb0474 288 PRINTS PR00126 ATP synthase gamma subunit signature 266 287 5.9E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14355 66d9405b7d2ce2364a1e069a12eb0474 288 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 288 1.5E-111 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14355 66d9405b7d2ce2364a1e069a12eb0474 288 SUPERFAMILY SSF52943 2 288 5.79E-97 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14355 66d9405b7d2ce2364a1e069a12eb0474 288 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 274 287 - T 28-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14355 66d9405b7d2ce2364a1e069a12eb0474 288 Gene3D G3DSA:1.10.287.80 2 41 2.2E-18 T 28-03-2018 A6A12_RS14355 66d9405b7d2ce2364a1e069a12eb0474 288 Gene3D G3DSA:1.10.287.80 240 283 1.5E-15 T 28-03-2018 A6A12_RS11660 79f4dae0f68f8f5dfe9e45f2f20eef18 758 Gene3D G3DSA:3.30.1360.40 240 333 4.1E-23 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 A6A12_RS11660 79f4dae0f68f8f5dfe9e45f2f20eef18 758 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 34 470 9.2E-135 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS11660 79f4dae0f68f8f5dfe9e45f2f20eef18 758 SUPERFAMILY SSF101904 499 743 5.36E-52 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal A6A12_RS11660 79f4dae0f68f8f5dfe9e45f2f20eef18 758 Gene3D G3DSA:3.90.199.10 36 218 3.4E-75 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS11660 79f4dae0f68f8f5dfe9e45f2f20eef18 758 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 6 745 33.66 T 28-03-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11660 79f4dae0f68f8f5dfe9e45f2f20eef18 758 Gene3D G3DSA:2.120.10.90 499 747 4.3E-42 T 28-03-2018 A6A12_RS11660 79f4dae0f68f8f5dfe9e45f2f20eef18 758 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 647 680 5.3E-7 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11660 79f4dae0f68f8f5dfe9e45f2f20eef18 758 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 547 588 2.9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11660 79f4dae0f68f8f5dfe9e45f2f20eef18 758 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 600 636 0.032 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11660 79f4dae0f68f8f5dfe9e45f2f20eef18 758 SMART SM00434 13 463 2.5E-230 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS11660 79f4dae0f68f8f5dfe9e45f2f20eef18 758 Gene3D G3DSA:1.10.268.10 346 485 2.1E-44 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS11660 79f4dae0f68f8f5dfe9e45f2f20eef18 758 SUPERFAMILY SSF56719 33 485 1.7E-154 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A6A12_RS11660 79f4dae0f68f8f5dfe9e45f2f20eef18 758 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 10 744 0.0 T 28-03-2018 A6A12_RS01695 af149ead25f05ab44a8574618e962ca4 406 Hamap MF_00242 Arginine deiminase [arcA]. 1 406 44.725 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS01695 af149ead25f05ab44a8574618e962ca4 406 PIRSF PIRSF006356 1 406 4.7E-154 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS01695 af149ead25f05ab44a8574618e962ca4 406 TIGRFAM TIGR01078 arcA: arginine deiminase 4 406 9.2E-171 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS01695 af149ead25f05ab44a8574618e962ca4 406 SUPERFAMILY SSF55909 3 406 1.96E-126 T 28-03-2018 A6A12_RS01695 af149ead25f05ab44a8574618e962ca4 406 PRINTS PR01466 Bacterial arginine deiminase signature 177 192 2.1E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS01695 af149ead25f05ab44a8574618e962ca4 406 PRINTS PR01466 Bacterial arginine deiminase signature 149 167 2.1E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS01695 af149ead25f05ab44a8574618e962ca4 406 PRINTS PR01466 Bacterial arginine deiminase signature 362 376 2.1E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS01695 af149ead25f05ab44a8574618e962ca4 406 PRINTS PR01466 Bacterial arginine deiminase signature 385 403 2.1E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS01695 af149ead25f05ab44a8574618e962ca4 406 PRINTS PR01466 Bacterial arginine deiminase signature 342 359 2.1E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS01695 af149ead25f05ab44a8574618e962ca4 406 PRINTS PR01466 Bacterial arginine deiminase signature 2 22 2.1E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS01695 af149ead25f05ab44a8574618e962ca4 406 Gene3D G3DSA:3.75.10.10 3 404 6.9E-94 T 28-03-2018 A6A12_RS01695 af149ead25f05ab44a8574618e962ca4 406 Pfam PF02274 Amidinotransferase 18 403 1.1E-110 T 28-03-2018 A6A12_RS07945 71fc6952fad7bbd02ae77751c2189e34 378 Gene3D G3DSA:3.40.1710.10 43 203 3.1E-25 T 28-03-2018 A6A12_RS07945 71fc6952fad7bbd02ae77751c2189e34 378 Pfam PF12698 ABC-2 family transporter protein 25 372 3.9E-42 T 28-03-2018 A6A12_RS09720 9a05ae497004e6364efeb09688cc5ff2 315 Pfam PF00849 RNA pseudouridylate synthase 103 248 4.7E-32 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS09720 9a05ae497004e6364efeb09688cc5ff2 315 Gene3D G3DSA:3.10.290.10 5 77 3.3E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS09720 9a05ae497004e6364efeb09688cc5ff2 315 SUPERFAMILY SSF55120 97 309 1.2E-62 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS09720 9a05ae497004e6364efeb09688cc5ff2 315 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 16 313 5.9E-91 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS09720 9a05ae497004e6364efeb09688cc5ff2 315 SMART SM00363 20 77 2.8E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS09720 9a05ae497004e6364efeb09688cc5ff2 315 Pfam PF01479 S4 domain 20 66 1.3E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS09720 9a05ae497004e6364efeb09688cc5ff2 315 SUPERFAMILY SSF55174 19 71 7.07E-9 T 28-03-2018 A6A12_RS09720 9a05ae497004e6364efeb09688cc5ff2 315 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 142 156 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS09720 9a05ae497004e6364efeb09688cc5ff2 315 Gene3D G3DSA:3.30.2350.10 94 315 8.6E-65 T 28-03-2018 A6A12_RS09005 0e25d1a630a03dc215aefaca804031f3 582 Pfam PF00005 ABC transporter 359 509 9.1E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS09005 0e25d1a630a03dc215aefaca804031f3 582 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 12 581 7.0E-242 T 28-03-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 A6A12_RS09005 0e25d1a630a03dc215aefaca804031f3 582 Gene3D G3DSA:1.20.1560.10 4 328 1.9E-65 T 28-03-2018 A6A12_RS09005 0e25d1a630a03dc215aefaca804031f3 582 Pfam PF00664 ABC transporter transmembrane region 28 293 1.6E-54 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A6A12_RS09005 0e25d1a630a03dc215aefaca804031f3 582 SUPERFAMILY SSF90123 14 327 5.62E-72 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A6A12_RS09005 0e25d1a630a03dc215aefaca804031f3 582 Gene3D G3DSA:3.40.50.300 329 580 6.4E-79 T 28-03-2018 A6A12_RS09005 0e25d1a630a03dc215aefaca804031f3 582 SUPERFAMILY SSF52540 334 580 5.83E-95 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09005 0e25d1a630a03dc215aefaca804031f3 582 ProSitePatterns PS00211 ABC transporters family signature. 481 495 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS09005 0e25d1a630a03dc215aefaca804031f3 582 SMART SM00382 368 555 1.1E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS04310 b6ce0afc10b26692afbff83f11853e69 396 Gene3D G3DSA:2.40.160.20 164 275 0.41 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A6A12_RS04310 b6ce0afc10b26692afbff83f11853e69 396 Gene3D G3DSA:2.40.160.20 41 161 0.25 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A6A12_RS04310 b6ce0afc10b26692afbff83f11853e69 396 Pfam PF10082 Putative beta-barrel porin 2 39 390 1.0E-27 T 28-03-2018 IPR018759 Putative beta-barrel porin 2 A6A12_RS04310 b6ce0afc10b26692afbff83f11853e69 396 Gene3D G3DSA:2.40.160.60 276 392 0.026 T 28-03-2018 A6A12_RS05015 3eefece519086db74e3112cc8e808b85 187 Pfam PF03843 Outer membrane lipoprotein Slp family 20 168 3.3E-45 T 28-03-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 A6A12_RS05015 3eefece519086db74e3112cc8e808b85 187 PIRSF PIRSF004982 5 187 2.1E-59 T 28-03-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 A6A12_RS05015 3eefece519086db74e3112cc8e808b85 187 TIGRFAM TIGR00752 slp: outer membrane lipoprotein, Slp family 8 160 3.8E-35 T 28-03-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 A6A12_RS01470 1d4ba4949594301bd67d54a1adedda93 577 Gene3D G3DSA:3.30.413.10 431 568 1.2E-22 T 28-03-2018 A6A12_RS01470 1d4ba4949594301bd67d54a1adedda93 577 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 15 577 58.039 T 28-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A6A12_RS01470 1d4ba4949594301bd67d54a1adedda93 577 PRINTS PR00397 Sirohaem Fe-binding site signature 435 453 5.9E-9 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A6A12_RS01470 1d4ba4949594301bd67d54a1adedda93 577 PRINTS PR00397 Sirohaem Fe-binding site signature 484 502 5.9E-9 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A6A12_RS01470 1d4ba4949594301bd67d54a1adedda93 577 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 24 565 3.2E-282 T 28-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A6A12_RS01470 1d4ba4949594301bd67d54a1adedda93 577 Gene3D G3DSA:3.30.413.10 146 350 1.5E-46 T 28-03-2018 A6A12_RS01470 1d4ba4949594301bd67d54a1adedda93 577 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 484 500 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A6A12_RS01470 1d4ba4949594301bd67d54a1adedda93 577 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 357 422 6.4E-13 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A6A12_RS01470 1d4ba4949594301bd67d54a1adedda93 577 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 84 143 6.7E-14 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A6A12_RS01470 1d4ba4949594301bd67d54a1adedda93 577 SUPERFAMILY SSF56014 434 566 9.68E-31 T 28-03-2018 A6A12_RS01470 1d4ba4949594301bd67d54a1adedda93 577 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 178 335 2.7E-45 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A6A12_RS01470 1d4ba4949594301bd67d54a1adedda93 577 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 436 524 2.4E-4 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A6A12_RS01470 1d4ba4949594301bd67d54a1adedda93 577 SUPERFAMILY SSF56014 154 349 1.44E-57 T 28-03-2018 A6A12_RS01470 1d4ba4949594301bd67d54a1adedda93 577 SUPERFAMILY SSF55124 17 150 2.78E-28 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A6A12_RS01470 1d4ba4949594301bd67d54a1adedda93 577 SUPERFAMILY SSF55124 351 429 5.72E-20 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 A6A12_RS11370 f071019c6061ed5ca478f965d4e177e0 318 PRINTS PR00958 Homoserine kinase signature 181 198 1.2E-30 T 28-03-2018 A6A12_RS11370 f071019c6061ed5ca478f965d4e177e0 318 PRINTS PR00958 Homoserine kinase signature 103 118 1.2E-30 T 28-03-2018 A6A12_RS11370 f071019c6061ed5ca478f965d4e177e0 318 PRINTS PR00958 Homoserine kinase signature 143 156 1.2E-30 T 28-03-2018 A6A12_RS11370 f071019c6061ed5ca478f965d4e177e0 318 PRINTS PR00958 Homoserine kinase signature 10 25 1.2E-30 T 28-03-2018 A6A12_RS11370 f071019c6061ed5ca478f965d4e177e0 318 PRINTS PR00958 Homoserine kinase signature 260 275 1.2E-30 T 28-03-2018 A6A12_RS11370 f071019c6061ed5ca478f965d4e177e0 318 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 96 107 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A6A12_RS11370 f071019c6061ed5ca478f965d4e177e0 318 Gene3D G3DSA:3.30.230.10 1 164 7.3E-27 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A6A12_RS11370 f071019c6061ed5ca478f965d4e177e0 318 Hamap MF_00384 Homoserine kinase [thrB]. 3 313 29.988 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A6A12_RS11370 f071019c6061ed5ca478f965d4e177e0 318 SUPERFAMILY SSF54211 3 191 4.63E-34 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS11370 f071019c6061ed5ca478f965d4e177e0 318 PIRSF PIRSF000676 1 316 6.4E-79 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A6A12_RS11370 f071019c6061ed5ca478f965d4e177e0 318 SUPERFAMILY SSF55060 178 295 4.68E-32 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A6A12_RS11370 f071019c6061ed5ca478f965d4e177e0 318 Pfam PF08544 GHMP kinases C terminal 217 293 2.1E-8 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A6A12_RS11370 f071019c6061ed5ca478f965d4e177e0 318 TIGRFAM TIGR00191 thrB: homoserine kinase 3 314 1.5E-109 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 A6A12_RS11370 f071019c6061ed5ca478f965d4e177e0 318 Pfam PF00288 GHMP kinases N terminal domain 90 156 1.7E-13 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A6A12_RS11370 f071019c6061ed5ca478f965d4e177e0 318 Gene3D G3DSA:3.30.70.890 173 317 1.5E-29 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A6A12_RS00840 e6720a72ee71341e4a76419799b0c72d 542 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 266 281 - T 28-03-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A6A12_RS00840 e6720a72ee71341e4a76419799b0c72d 542 Gene3D G3DSA:3.90.228.20 229 309 7.0E-28 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A6A12_RS00840 e6720a72ee71341e4a76419799b0c72d 542 Gene3D G3DSA:3.90.228.20 310 539 1.4E-91 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A6A12_RS00840 e6720a72ee71341e4a76419799b0c72d 542 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 18 539 54.497 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A6A12_RS00840 e6720a72ee71341e4a76419799b0c72d 542 Gene3D G3DSA:3.40.449.10 25 228 4.3E-76 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A6A12_RS00840 e6720a72ee71341e4a76419799b0c72d 542 Pfam PF01293 Phosphoenolpyruvate carboxykinase 24 491 1.8E-209 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A6A12_RS00840 e6720a72ee71341e4a76419799b0c72d 542 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 11 541 1.6E-275 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A6A12_RS00840 e6720a72ee71341e4a76419799b0c72d 542 PIRSF PIRSF006294 4 541 2.0E-225 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 A6A12_RS00840 e6720a72ee71341e4a76419799b0c72d 542 SUPERFAMILY SSF68923 11 228 1.33E-86 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A6A12_RS00840 e6720a72ee71341e4a76419799b0c72d 542 SUPERFAMILY SSF53795 230 541 1.23E-126 T 28-03-2018 A6A12_RS04000 8df90c69ceb2cde141a765c76d900cad 231 Pfam PF01980 Uncharacterised protein family UPF0066 19 141 9.9E-37 T 28-03-2018 IPR023370 TsaA-like domain A6A12_RS04000 8df90c69ceb2cde141a765c76d900cad 231 SUPERFAMILY SSF118196 2 226 3.01E-76 T 28-03-2018 IPR023370 TsaA-like domain A6A12_RS04000 8df90c69ceb2cde141a765c76d900cad 231 Gene3D G3DSA:2.40.30.70 3 147 6.3E-48 T 28-03-2018 IPR023370 TsaA-like domain A6A12_RS04000 8df90c69ceb2cde141a765c76d900cad 231 ProSitePatterns PS01318 TsaA-like domain signature. 85 96 - T 28-03-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site A6A12_RS04000 8df90c69ceb2cde141a765c76d900cad 231 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 3 146 2.8E-46 T 28-03-2018 IPR023370 TsaA-like domain A6A12_RS04000 8df90c69ceb2cde141a765c76d900cad 231 Gene3D G3DSA:3.30.2310.10 148 227 2.0E-21 T 28-03-2018 A6A12_RS04675 c0a09828621eb91d9d602750a30a5dbd 693 Pfam PF07715 TonB-dependent Receptor Plug Domain 74 176 8.0E-8 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 A6A12_RS04675 c0a09828621eb91d9d602750a30a5dbd 693 Pfam PF00593 TonB dependent receptor 263 690 3.1E-39 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A6A12_RS04675 c0a09828621eb91d9d602750a30a5dbd 693 SUPERFAMILY SSF56935 49 693 1.03E-96 T 28-03-2018 A6A12_RS04675 c0a09828621eb91d9d602750a30a5dbd 693 Gene3D G3DSA:2.170.130.10 42 185 2.4E-15 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 A6A12_RS04675 c0a09828621eb91d9d602750a30a5dbd 693 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 59 - T 28-03-2018 IPR010916 TonB box, conserved site A6A12_RS04675 c0a09828621eb91d9d602750a30a5dbd 693 Gene3D G3DSA:2.40.170.20 186 693 5.2E-64 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 Pfam PF08206 Ribonuclease B OB domain 91 151 8.8E-21 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 SUPERFAMILY SSF50249 145 244 1.16E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 SUPERFAMILY SSF50249 71 154 6.52E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 SMART SM00316 650 733 2.2E-14 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 TIGRFAM TIGR02063 RNase_R: ribonuclease R 23 733 3.7E-272 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 Hamap MF_01895 Ribonuclease R [rnr]. 42 733 59.287 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 Pfam PF00575 S1 RNA binding domain 650 732 2.0E-13 T 28-03-2018 IPR003029 S1 domain GO:0003676 A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 SMART SM00955 267 595 8.4E-184 T 28-03-2018 A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 SUPERFAMILY SSF50249 227 650 2.11E-143 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 Pfam PF08461 Ribonuclease R winged-helix domain 27 88 1.1E-11 T 28-03-2018 IPR013668 Ribonuclease R winged-helix domain A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 71 733 1.5E-256 T 28-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 Gene3D G3DSA:1.10.10.10 22 83 2.1E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 SMART SM00357 90 152 2.7E-11 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 ProSitePatterns PS01175 Ribonuclease II family signature. 562 586 - T 28-03-2018 IPR022966 Ribonuclease II/R, conserved site A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 SUPERFAMILY SSF50249 651 740 1.57E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 Pfam PF00773 RNB domain 267 594 1.4E-107 T 28-03-2018 A6A12_RS12520 9609bbebf52c66dac9b975213603f88c 815 Gene3D G3DSA:2.40.50.140 649 734 9.9E-21 T 28-03-2018 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 Gene3D G3DSA:3.30.565.10 17 216 1.4E-65 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 Pfam PF00204 DNA gyrase B 218 384 2.5E-41 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 Pfam PF01751 Toprim domain 413 512 1.6E-11 T 28-03-2018 IPR006171 TOPRIM domain A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 SUPERFAMILY SSF56719 388 620 8.11E-79 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR01098 Topoisomerase IV subunit B signature 448 469 1.7E-125 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR01098 Topoisomerase IV subunit B signature 238 261 1.7E-125 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR01098 Topoisomerase IV subunit B signature 503 519 1.7E-125 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR01098 Topoisomerase IV subunit B signature 338 361 1.7E-125 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR01098 Topoisomerase IV subunit B signature 537 559 1.7E-125 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR01098 Topoisomerase IV subunit B signature 149 164 1.7E-125 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR01098 Topoisomerase IV subunit B signature 311 326 1.7E-125 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR01098 Topoisomerase IV subunit B signature 362 387 1.7E-125 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR01098 Topoisomerase IV subunit B signature 26 39 1.7E-125 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR01098 Topoisomerase IV subunit B signature 192 213 1.7E-125 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR01098 Topoisomerase IV subunit B signature 135 149 1.7E-125 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR01098 Topoisomerase IV subunit B signature 174 191 1.7E-125 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR01098 Topoisomerase IV subunit B signature 294 310 1.7E-125 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR01098 Topoisomerase IV subunit B signature 469 481 1.7E-125 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 556 618 8.8E-28 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 Gene3D G3DSA:3.40.50.670 396 625 9.5E-81 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 2 626 46.762 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 Gene3D G3DSA:3.30.230.10 217 391 1.1E-39 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 SUPERFAMILY SSF54211 217 382 1.74E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 SMART SM00387 27 173 4.7E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 SUPERFAMILY SSF55874 5 215 5.16E-67 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR00418 DNA topoisomerase II family signature 109 123 6.5E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR00418 DNA topoisomerase II family signature 479 495 6.5E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR00418 DNA topoisomerase II family signature 560 576 6.5E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR00418 DNA topoisomerase II family signature 31 46 6.5E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR00418 DNA topoisomerase II family signature 497 514 6.5E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR00418 DNA topoisomerase II family signature 517 529 6.5E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR00418 DNA topoisomerase II family signature 266 279 6.5E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR00418 DNA topoisomerase II family signature 414 428 6.5E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 PRINTS PR00418 DNA topoisomerase II family signature 66 79 6.5E-57 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 3 623 0.0 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 170 8.1E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS11665 be5b045c8b54706625c69c8311079ac7 627 SMART SM00433 34 622 4.2E-215 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS12755 ccd6bd4ca4929d11d352b14ae03eb054 378 SUPERFAMILY SSF53187 3 176 2.74E-53 T 28-03-2018 A6A12_RS12755 ccd6bd4ca4929d11d352b14ae03eb054 378 SUPERFAMILY SSF53187 301 377 2.74E-53 T 28-03-2018 A6A12_RS12755 ccd6bd4ca4929d11d352b14ae03eb054 378 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 8 371 3.1E-125 T 28-03-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 A6A12_RS12755 ccd6bd4ca4929d11d352b14ae03eb054 378 Pfam PF01546 Peptidase family M20/M25/M40 72 373 5.3E-31 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A6A12_RS12755 ccd6bd4ca4929d11d352b14ae03eb054 378 Gene3D G3DSA:3.40.630.10 1 180 6.5E-25 T 28-03-2018 A6A12_RS12755 ccd6bd4ca4929d11d352b14ae03eb054 378 Pfam PF07687 Peptidase dimerisation domain 174 285 1.4E-26 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A6A12_RS12755 ccd6bd4ca4929d11d352b14ae03eb054 378 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 106 143 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A6A12_RS12755 ccd6bd4ca4929d11d352b14ae03eb054 378 Gene3D G3DSA:3.30.70.360 181 298 6.9E-23 T 28-03-2018 A6A12_RS12755 ccd6bd4ca4929d11d352b14ae03eb054 378 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 71 80 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A6A12_RS12755 ccd6bd4ca4929d11d352b14ae03eb054 378 Hamap MF_01108 Acetylornithine deacetylase [argE]. 1 378 63.382 T 28-03-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 A6A12_RS12755 ccd6bd4ca4929d11d352b14ae03eb054 378 SUPERFAMILY SSF55031 177 291 2.24E-23 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A6A12_RS06305 3ebbf50122c6854f0178e449a8b9e81a 285 SUPERFAMILY SSF46689 234 282 6.05E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS06305 3ebbf50122c6854f0178e449a8b9e81a 285 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 235 277 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A6A12_RS06305 3ebbf50122c6854f0178e449a8b9e81a 285 Pfam PF12833 Helix-turn-helix domain 204 282 6.7E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A6A12_RS06305 3ebbf50122c6854f0178e449a8b9e81a 285 Gene3D G3DSA:2.60.120.10 21 237 8.1E-18 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS06305 3ebbf50122c6854f0178e449a8b9e81a 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 250 265 4.2E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A6A12_RS06305 3ebbf50122c6854f0178e449a8b9e81a 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 265 281 4.2E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A6A12_RS06305 3ebbf50122c6854f0178e449a8b9e81a 285 Gene3D G3DSA:1.10.10.60 238 285 2.6E-13 T 28-03-2018 A6A12_RS06305 3ebbf50122c6854f0178e449a8b9e81a 285 SMART SM00342 198 281 1.9E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A6A12_RS06305 3ebbf50122c6854f0178e449a8b9e81a 285 SUPERFAMILY SSF46689 184 231 1.5E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS00810 56710f7cd621261bd36978a0a51a63db 469 SMART SM01230 102 379 7.8E-152 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A6A12_RS00810 56710f7cd621261bd36978a0a51a63db 469 SUPERFAMILY SSF54368 3 100 6.8E-36 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A6A12_RS00810 56710f7cd621261bd36978a0a51a63db 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 386 398 - T 28-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A6A12_RS00810 56710f7cd621261bd36978a0a51a63db 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A6A12_RS00810 56710f7cd621261bd36978a0a51a63db 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 50 68 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A6A12_RS00810 56710f7cd621261bd36978a0a51a63db 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 4 468 4.2E-211 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A6A12_RS00810 56710f7cd621261bd36978a0a51a63db 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 95 1.2E-30 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A6A12_RS00810 56710f7cd621261bd36978a0a51a63db 469 Gene3D G3DSA:3.30.590.10 105 457 2.4E-123 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A6A12_RS00810 56710f7cd621261bd36978a0a51a63db 469 SUPERFAMILY SSF55931 102 468 1.86E-137 T 28-03-2018 A6A12_RS00810 56710f7cd621261bd36978a0a51a63db 469 Pfam PF00120 Glutamine synthetase, catalytic domain 103 466 1.8E-138 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A6A12_RS00810 56710f7cd621261bd36978a0a51a63db 469 Gene3D G3DSA:3.10.20.70 2 104 6.0E-28 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A6A12_RS11795 ec9189c0994f0acece2f8d7da7c411df 324 SUPERFAMILY SSF54814 204 320 4.25E-41 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 A6A12_RS11795 ec9189c0994f0acece2f8d7da7c411df 324 SUPERFAMILY SSF52540 33 228 6.11E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11795 ec9189c0994f0acece2f8d7da7c411df 324 Gene3D G3DSA:3.40.50.300 48 203 1.7E-30 T 28-03-2018 A6A12_RS11795 ec9189c0994f0acece2f8d7da7c411df 324 Hamap MF_00367 GTPase Era [era]. 28 320 35.763 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS11795 ec9189c0994f0acece2f8d7da7c411df 324 Gene3D G3DSA:3.40.50.300 28 47 0.0056 T 28-03-2018 A6A12_RS11795 ec9189c0994f0acece2f8d7da7c411df 324 Pfam PF07650 KH domain 231 308 4.4E-21 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS11795 ec9189c0994f0acece2f8d7da7c411df 324 TIGRFAM TIGR00436 era: GTP-binding protein Era 31 303 6.3E-110 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS11795 ec9189c0994f0acece2f8d7da7c411df 324 Gene3D G3DSA:3.30.300.20 208 323 1.3E-41 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A6A12_RS11795 ec9189c0994f0acece2f8d7da7c411df 324 Pfam PF01926 50S ribosome-binding GTPase 33 147 1.2E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS11795 ec9189c0994f0acece2f8d7da7c411df 324 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 30 192 3.0E-38 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A6A12_RS12370 3681606188949f81ef35469b8f96a39b 206 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 116 203 1.1E-26 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A6A12_RS12370 3681606188949f81ef35469b8f96a39b 206 Gene3D G3DSA:3.10.50.40 95 206 6.2E-39 T 28-03-2018 A6A12_RS12370 3681606188949f81ef35469b8f96a39b 206 SUPERFAMILY SSF54534 7 205 4.71E-54 T 28-03-2018 A6A12_RS12370 3681606188949f81ef35469b8f96a39b 206 Gene3D G3DSA:1.10.287.460 1 94 6.0E-19 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 A6A12_RS12370 3681606188949f81ef35469b8f96a39b 206 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 2 108 1.1E-22 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 A6A12_RS01590 05c0d74757943b4c1996284fe4e1c6d8 542 Pfam PF00263 Bacterial type II and III secretion system protein 343 518 9.6E-42 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 A6A12_RS01590 05c0d74757943b4c1996284fe4e1c6d8 542 SMART SM00965 93 141 6.4E-4 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 A6A12_RS01590 05c0d74757943b4c1996284fe4e1c6d8 542 Pfam PF07655 Secretin N-terminal domain 145 240 5.0E-26 T 28-03-2018 IPR011514 Secretin, N-terminal GO:0009297|GO:0019867 A6A12_RS01590 05c0d74757943b4c1996284fe4e1c6d8 542 PRINTS PR00811 Bacterial general secretion pathway protein D signature 338 362 2.0E-17 T 28-03-2018 IPR001775 GspD/PilQ family A6A12_RS01590 05c0d74757943b4c1996284fe4e1c6d8 542 PRINTS PR00811 Bacterial general secretion pathway protein D signature 483 501 2.0E-17 T 28-03-2018 IPR001775 GspD/PilQ family A6A12_RS01590 05c0d74757943b4c1996284fe4e1c6d8 542 PRINTS PR00811 Bacterial general secretion pathway protein D signature 269 279 2.0E-17 T 28-03-2018 IPR001775 GspD/PilQ family A6A12_RS01590 05c0d74757943b4c1996284fe4e1c6d8 542 PRINTS PR00811 Bacterial general secretion pathway protein D signature 506 520 2.0E-17 T 28-03-2018 IPR001775 GspD/PilQ family A6A12_RS01590 05c0d74757943b4c1996284fe4e1c6d8 542 TIGRFAM TIGR02519 pilus_MshL: pilus (MSHA type) biogenesis protein MshL 235 518 5.9E-91 T 28-03-2018 IPR013358 Pilus biogenesis, MshL A6A12_RS03895 749d0cd20a75a28840349234faacb31e 205 PRINTS PR00773 GrpE protein signature 74 90 2.6E-28 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A6A12_RS03895 749d0cd20a75a28840349234faacb31e 205 PRINTS PR00773 GrpE protein signature 157 172 2.6E-28 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A6A12_RS03895 749d0cd20a75a28840349234faacb31e 205 PRINTS PR00773 GrpE protein signature 102 117 2.6E-28 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A6A12_RS03895 749d0cd20a75a28840349234faacb31e 205 PRINTS PR00773 GrpE protein signature 184 203 2.6E-28 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A6A12_RS03895 749d0cd20a75a28840349234faacb31e 205 Hamap MF_01151 Protein GrpE [grpE]. 8 205 22.604 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A6A12_RS03895 749d0cd20a75a28840349234faacb31e 205 Gene3D G3DSA:2.30.22.10 149 205 1.3E-23 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A6A12_RS03895 749d0cd20a75a28840349234faacb31e 205 Pfam PF01025 GrpE 44 205 4.8E-54 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A6A12_RS03895 749d0cd20a75a28840349234faacb31e 205 SUPERFAMILY SSF51064 150 205 3.4E-20 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 A6A12_RS03895 749d0cd20a75a28840349234faacb31e 205 ProSitePatterns PS01071 grpE protein signature. 160 203 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 A6A12_RS03895 749d0cd20a75a28840349234faacb31e 205 SUPERFAMILY SSF58014 51 149 8.63E-29 T 28-03-2018 A6A12_RS03895 749d0cd20a75a28840349234faacb31e 205 Gene3D G3DSA:3.90.20.20 39 148 1.7E-30 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 A6A12_RS06840 7d5e85f403cdacd8a6331816df75136e 173 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 11 167 1.0E-43 T 28-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A6A12_RS06840 7d5e85f403cdacd8a6331816df75136e 173 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 11 143 1.1E-47 T 28-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A6A12_RS06840 7d5e85f403cdacd8a6331816df75136e 173 Gene3D G3DSA:3.40.50.300 3 173 9.0E-26 T 28-03-2018 A6A12_RS06840 7d5e85f403cdacd8a6331816df75136e 173 SUPERFAMILY SSF52540 8 169 1.11E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS02570 982262c0d190a2d953841a45004b6cfc 248 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 248 117.753 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A6A12_RS02570 982262c0d190a2d953841a45004b6cfc 248 Gene3D G3DSA:3.40.1280.10 1 169 1.3E-73 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A6A12_RS02570 982262c0d190a2d953841a45004b6cfc 248 SUPERFAMILY SSF75217 1 245 7.19E-102 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases A6A12_RS02570 982262c0d190a2d953841a45004b6cfc 248 Gene3D G3DSA:1.10.1270.20 170 248 1.6E-31 T 28-03-2018 A6A12_RS02570 982262c0d190a2d953841a45004b6cfc 248 PIRSF PIRSF000386 1 247 9.1E-102 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A6A12_RS02570 982262c0d190a2d953841a45004b6cfc 248 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 233 4.9E-109 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A6A12_RS02570 982262c0d190a2d953841a45004b6cfc 248 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 1.1E-70 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 A6A12_RS02360 56e2f8272fd8ed47de26ba80825e1e3e 200 Pfam PF02660 Glycerol-3-phosphate acyltransferase 12 184 4.3E-52 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A6A12_RS02360 56e2f8272fd8ed47de26ba80825e1e3e 200 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 1 194 3.1E-76 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A6A12_RS02360 56e2f8272fd8ed47de26ba80825e1e3e 200 SMART SM01207 10 185 1.2E-85 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A6A12_RS02360 56e2f8272fd8ed47de26ba80825e1e3e 200 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 7 193 19.37 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 A6A12_RS08955 09f05b87090c4cc0af1f35fbcc00fa8f 246 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 6 239 3.8E-108 T 28-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 A6A12_RS08955 09f05b87090c4cc0af1f35fbcc00fa8f 246 SUPERFAMILY SSF102114 23 220 3.34E-29 T 28-03-2018 A6A12_RS08955 09f05b87090c4cc0af1f35fbcc00fa8f 246 Pfam PF13353 4Fe-4S single cluster domain 16 137 4.0E-20 T 28-03-2018 A6A12_RS08955 09f05b87090c4cc0af1f35fbcc00fa8f 246 Pfam PF04055 Radical SAM superfamily 24 178 7.8E-32 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A6A12_RS08955 09f05b87090c4cc0af1f35fbcc00fa8f 246 ProSitePatterns PS01087 Radical activating enzymes signature. 18 39 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 A6A12_RS08955 09f05b87090c4cc0af1f35fbcc00fa8f 246 Gene3D G3DSA:3.80.30.10 68 246 3.5E-41 T 28-03-2018 A6A12_RS08955 09f05b87090c4cc0af1f35fbcc00fa8f 246 PIRSF PIRSF000371 44 242 1.4E-44 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 A6A12_RS08955 09f05b87090c4cc0af1f35fbcc00fa8f 246 PIRSF PIRSF000371 1 47 5.2E-11 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 A6A12_RS05025 ba823dfef9e802ebd699da13ac3bf0ec 564 Gene3D G3DSA:3.40.50.980 217 371 5.2E-38 T 28-03-2018 A6A12_RS05025 ba823dfef9e802ebd699da13ac3bf0ec 564 Gene3D G3DSA:3.40.50.980 20 216 1.0E-40 T 28-03-2018 A6A12_RS05025 ba823dfef9e802ebd699da13ac3bf0ec 564 Pfam PF00501 AMP-binding enzyme 29 461 7.7E-105 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A6A12_RS05025 ba823dfef9e802ebd699da13ac3bf0ec 564 SUPERFAMILY SSF56801 12 554 3.92E-148 T 28-03-2018 A6A12_RS05025 ba823dfef9e802ebd699da13ac3bf0ec 564 Gene3D G3DSA:2.30.38.10 372 454 5.2E-29 T 28-03-2018 A6A12_RS05025 ba823dfef9e802ebd699da13ac3bf0ec 564 Gene3D G3DSA:3.30.300.30 456 564 1.4E-24 T 28-03-2018 A6A12_RS05025 ba823dfef9e802ebd699da13ac3bf0ec 564 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 28-03-2018 IPR020845 AMP-binding, conserved site A6A12_RS05025 ba823dfef9e802ebd699da13ac3bf0ec 564 Pfam PF13193 AMP-binding enzyme C-terminal domain 470 544 7.6E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A6A12_RS05170 9b46ebaf0a87478c848f2970747c218b 446 SMART SM00448 2 114 1.6E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS05170 9b46ebaf0a87478c848f2970747c218b 446 SMART SM00382 164 308 7.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS05170 9b46ebaf0a87478c848f2970747c218b 446 Pfam PF00158 Sigma-54 interaction domain 144 310 1.6E-68 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A6A12_RS05170 9b46ebaf0a87478c848f2970747c218b 446 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 168 181 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A6A12_RS05170 9b46ebaf0a87478c848f2970747c218b 446 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 230 245 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A6A12_RS05170 9b46ebaf0a87478c848f2970747c218b 446 Gene3D G3DSA:3.40.50.300 141 316 1.3E-25 T 28-03-2018 A6A12_RS05170 9b46ebaf0a87478c848f2970747c218b 446 SUPERFAMILY SSF52540 144 374 2.58E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05170 9b46ebaf0a87478c848f2970747c218b 446 Gene3D G3DSA:3.40.50.2300 2 140 1.6E-26 T 28-03-2018 A6A12_RS05170 9b46ebaf0a87478c848f2970747c218b 446 SUPERFAMILY SSF46689 355 440 5.82E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS05170 9b46ebaf0a87478c848f2970747c218b 446 Pfam PF02954 Bacterial regulatory protein, Fis family 397 437 4.7E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS05170 9b46ebaf0a87478c848f2970747c218b 446 Gene3D G3DSA:1.10.8.60 317 396 1.6E-23 T 28-03-2018 A6A12_RS05170 9b46ebaf0a87478c848f2970747c218b 446 Pfam PF00072 Response regulator receiver domain 4 114 2.0E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS05170 9b46ebaf0a87478c848f2970747c218b 446 Gene3D G3DSA:1.10.10.60 397 444 6.2E-16 T 28-03-2018 A6A12_RS05170 9b46ebaf0a87478c848f2970747c218b 446 SUPERFAMILY SSF52172 2 188 7.97E-36 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS05170 9b46ebaf0a87478c848f2970747c218b 446 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 357 366 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A6A12_RS00165 0832eb9be28e7d9b98d204dfa17a5cf8 168 SUPERFAMILY SSF102712 28 146 3.14E-12 T 28-03-2018 A6A12_RS00165 0832eb9be28e7d9b98d204dfa17a5cf8 168 Gene3D G3DSA:3.40.140.10 25 168 1.6E-15 T 28-03-2018 A6A12_RS00165 0832eb9be28e7d9b98d204dfa17a5cf8 168 Pfam PF14464 Prokaryotic homologs of the JAB domain 32 146 4.2E-13 T 28-03-2018 IPR028090 JAB domain, prokaryotic A6A12_RS02830 6e5af3d73569f733e4742b10fcb83980 327 SUPERFAMILY SSF52540 5 252 4.75E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS02830 6e5af3d73569f733e4742b10fcb83980 327 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS02830 6e5af3d73569f733e4742b10fcb83980 327 SMART SM00382 34 231 8.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS02830 6e5af3d73569f733e4742b10fcb83980 327 Pfam PF00005 ABC transporter 26 181 1.3E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS02830 6e5af3d73569f733e4742b10fcb83980 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 317 5.4E-22 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A6A12_RS02830 6e5af3d73569f733e4742b10fcb83980 327 Gene3D G3DSA:3.40.50.300 2 326 3.9E-71 T 28-03-2018 A6A12_RS02830 6e5af3d73569f733e4742b10fcb83980 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 297 2.8E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 4 301 3.8E-130 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 Pfam PF00365 Phosphofructokinase 4 276 1.1E-109 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 Gene3D G3DSA:3.40.50.450 1 210 2.4E-84 T 28-03-2018 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 PIRSF PIRSF000532 1 320 2.7E-128 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 2 320 46.947 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 ProSitePatterns PS00433 Phosphofructokinase signature. 244 262 - T 28-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 Gene3D G3DSA:3.40.50.450 211 309 3.8E-9 T 28-03-2018 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 SUPERFAMILY SSF53784 3 315 2.62E-113 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 7 26 6.2E-82 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 6.2E-82 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 6.2E-82 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 6.2E-82 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 32 45 6.2E-82 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 94 110 6.2E-82 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 6.2E-82 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 6.2E-82 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A6A12_RS12950 647a731730d16677d8d7486bd46fe901 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 240 262 6.2E-82 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 A6A12_RS00260 c2f9024701a93a32dd538450a8b7e822 315 SUPERFAMILY SSF53328 5 210 6.02E-66 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A6A12_RS00260 c2f9024701a93a32dd538450a8b7e822 315 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 136 159 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A6A12_RS00260 c2f9024701a93a32dd538450a8b7e822 315 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 5 311 2.6E-106 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A6A12_RS00260 c2f9024701a93a32dd538450a8b7e822 315 SUPERFAMILY SSF50486 208 310 2.94E-32 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 A6A12_RS00260 c2f9024701a93a32dd538450a8b7e822 315 Gene3D G3DSA:3.40.50.170 2 209 2.8E-69 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A6A12_RS00260 c2f9024701a93a32dd538450a8b7e822 315 Pfam PF00551 Formyl transferase 6 183 8.6E-50 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A6A12_RS00260 c2f9024701a93a32dd538450a8b7e822 315 Gene3D G3DSA:3.10.25.10 210 315 9.8E-28 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A6A12_RS00260 c2f9024701a93a32dd538450a8b7e822 315 Pfam PF02911 Formyl transferase, C-terminal domain 207 303 4.3E-27 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A6A12_RS00260 c2f9024701a93a32dd538450a8b7e822 315 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 5 306 36.711 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 A6A12_RS12840 19ca810ca85f646c855d72217ff61708 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 A6A12_RS12840 19ca810ca85f646c855d72217ff61708 96 Gene3D G3DSA:2.30.33.40 1 96 6.6E-33 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A6A12_RS12840 19ca810ca85f646c855d72217ff61708 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 96 24.127 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A6A12_RS12840 19ca810ca85f646c855d72217ff61708 96 Pfam PF00166 Chaperonin 10 Kd subunit 2 95 9.5E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A6A12_RS12840 19ca810ca85f646c855d72217ff61708 96 SUPERFAMILY SSF50129 1 96 2.35E-31 T 28-03-2018 IPR011032 GroES-like A6A12_RS12840 19ca810ca85f646c855d72217ff61708 96 PRINTS PR00297 10kDa chaperonin signature 82 95 5.6E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A6A12_RS12840 19ca810ca85f646c855d72217ff61708 96 PRINTS PR00297 10kDa chaperonin signature 3 18 5.6E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A6A12_RS12840 19ca810ca85f646c855d72217ff61708 96 PRINTS PR00297 10kDa chaperonin signature 60 72 5.6E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A6A12_RS12840 19ca810ca85f646c855d72217ff61708 96 PRINTS PR00297 10kDa chaperonin signature 25 46 5.6E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A6A12_RS12840 19ca810ca85f646c855d72217ff61708 96 SMART SM00883 2 95 5.1E-50 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 A6A12_RS11700 aa6ee5a2edfaa7f83258f365f6fe1099 948 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 557 809 1.3E-98 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 A6A12_RS11700 aa6ee5a2edfaa7f83258f365f6fe1099 948 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 34 280 5.3E-92 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 A6A12_RS11700 aa6ee5a2edfaa7f83258f365f6fe1099 948 Gene3D G3DSA:3.30.460.10 642 815 8.7E-57 T 28-03-2018 A6A12_RS11700 aa6ee5a2edfaa7f83258f365f6fe1099 948 Gene3D G3DSA:3.30.460.10 115 288 4.8E-57 T 28-03-2018 A6A12_RS11700 aa6ee5a2edfaa7f83258f365f6fe1099 948 SUPERFAMILY SSF81301 529 816 8.92E-89 T 28-03-2018 A6A12_RS11700 aa6ee5a2edfaa7f83258f365f6fe1099 948 Gene3D G3DSA:1.20.120.330 816 948 2.7E-33 T 28-03-2018 A6A12_RS11700 aa6ee5a2edfaa7f83258f365f6fe1099 948 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 31 948 19.187 T 28-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 A6A12_RS11700 aa6ee5a2edfaa7f83258f365f6fe1099 948 Gene3D G3DSA:1.10.4050.10 4 112 3.2E-12 T 28-03-2018 A6A12_RS11700 aa6ee5a2edfaa7f83258f365f6fe1099 948 Gene3D G3DSA:1.10.4050.10 534 641 5.5E-21 T 28-03-2018 A6A12_RS11700 aa6ee5a2edfaa7f83258f365f6fe1099 948 Pfam PF08335 GlnD PII-uridylyltransferase 301 440 1.3E-45 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 A6A12_RS11700 aa6ee5a2edfaa7f83258f365f6fe1099 948 Pfam PF08335 GlnD PII-uridylyltransferase 846 916 5.1E-7 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 A6A12_RS11700 aa6ee5a2edfaa7f83258f365f6fe1099 948 Gene3D G3DSA:1.20.120.330 289 444 3.9E-48 T 28-03-2018 A6A12_RS11700 aa6ee5a2edfaa7f83258f365f6fe1099 948 SUPERFAMILY SSF81593 819 947 6.59E-32 T 28-03-2018 A6A12_RS11700 aa6ee5a2edfaa7f83258f365f6fe1099 948 SUPERFAMILY SSF81593 291 440 1.8E-43 T 28-03-2018 A6A12_RS11700 aa6ee5a2edfaa7f83258f365f6fe1099 948 SUPERFAMILY SSF81301 24 290 2.88E-87 T 28-03-2018 A6A12_RS09505 a6650d45363420273ea03a659b4ff3cb 289 Pfam PF07466 Protein of unknown function (DUF1517) 28 123 1.2E-5 T 28-03-2018 IPR010903 Protein of unknown function DUF1517 A6A12_RS09505 a6650d45363420273ea03a659b4ff3cb 289 Pfam PF04280 Tim44-like domain 167 288 4.0E-13 T 28-03-2018 IPR007379 Tim44-like domain A6A12_RS09505 a6650d45363420273ea03a659b4ff3cb 289 SMART SM00978 158 289 5.7E-35 T 28-03-2018 IPR007379 Tim44-like domain A6A12_RS09505 a6650d45363420273ea03a659b4ff3cb 289 SUPERFAMILY SSF54427 168 288 4.03E-14 T 28-03-2018 IPR032710 NTF2-like domain A6A12_RS09695 9c3597ee92f189e2079115f97079d897 316 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 316 9.0E-143 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A6A12_RS09695 9c3597ee92f189e2079115f97079d897 316 Gene3D G3DSA:3.40.47.10 163 316 1.3E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS09695 9c3597ee92f189e2079115f97079d897 316 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 183 2.0E-31 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A6A12_RS09695 9c3597ee92f189e2079115f97079d897 316 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 316 72.002 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A6A12_RS09695 9c3597ee92f189e2079115f97079d897 316 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 227 315 2.2E-34 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A6A12_RS09695 9c3597ee92f189e2079115f97079d897 316 SUPERFAMILY SSF53901 3 315 3.3E-70 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS09695 9c3597ee92f189e2079115f97079d897 316 Gene3D G3DSA:3.40.47.10 4 162 1.3E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS09870 59fcbccd828183ca430031cdb4ef2ef0 207 SUPERFAMILY SSF52540 2 194 7.41E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09870 59fcbccd828183ca430031cdb4ef2ef0 207 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS09870 59fcbccd828183ca430031cdb4ef2ef0 207 Gene3D G3DSA:3.40.50.300 1 197 7.1E-41 T 28-03-2018 A6A12_RS09870 59fcbccd828183ca430031cdb4ef2ef0 207 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 2 202 1.7E-77 T 28-03-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 A6A12_RS09870 59fcbccd828183ca430031cdb4ef2ef0 207 Pfam PF00005 ABC transporter 19 158 1.6E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS09870 59fcbccd828183ca430031cdb4ef2ef0 207 SMART SM00382 26 207 1.4E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS04105 b97a0b0e3d208aa52c4d92c0cbe674ba 518 SUPERFAMILY SSF55073 363 517 8.63E-38 T 28-03-2018 IPR029787 Nucleotide cyclase A6A12_RS04105 b97a0b0e3d208aa52c4d92c0cbe674ba 518 Gene3D G3DSA:3.30.70.270 341 518 4.4E-41 T 28-03-2018 A6A12_RS04105 b97a0b0e3d208aa52c4d92c0cbe674ba 518 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 359 516 1.6E-36 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS04105 b97a0b0e3d208aa52c4d92c0cbe674ba 518 Pfam PF00990 Diguanylate cyclase, GGDEF domain 360 513 2.7E-35 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS04105 b97a0b0e3d208aa52c4d92c0cbe674ba 518 SMART SM00267 348 518 4.8E-39 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS03880 a493fa4004d7c35d6051e29c407bf3d1 554 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 551 2.0E-174 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A6A12_RS03880 a493fa4004d7c35d6051e29c407bf3d1 554 SUPERFAMILY SSF52540 1 199 4.39E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03880 a493fa4004d7c35d6051e29c407bf3d1 554 SUPERFAMILY SSF52540 344 509 4.39E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03880 a493fa4004d7c35d6051e29c407bf3d1 554 SUPERFAMILY SSF52540 287 315 4.39E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03880 a493fa4004d7c35d6051e29c407bf3d1 554 Gene3D G3DSA:3.40.50.300 1 533 9.6E-40 T 28-03-2018 A6A12_RS03880 a493fa4004d7c35d6051e29c407bf3d1 554 PIRSF PIRSF003128 1 554 1.0E-161 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 A6A12_RS03880 a493fa4004d7c35d6051e29c407bf3d1 554 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 507 2.6E-18 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 Gene3D G3DSA:3.30.2090.10 698 784 1.1E-12 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 Gene3D G3DSA:1.20.1640.10 280 502 1.6E-42 T 28-03-2018 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 SUPERFAMILY SSF82693 136 181 3.84E-20 T 28-03-2018 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 SUPERFAMILY SSF82693 267 323 3.84E-20 T 28-03-2018 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 Pfam PF00873 AcrB/AcrD/AcrF family 4 1003 1.1E-271 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 SUPERFAMILY SSF82714 182 263 1.28E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.9E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.9E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 5.9E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 5.9E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 5.9E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 PRINTS PR00702 Acriflavin resistance protein family signature 603 617 5.9E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 5.9E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 5.9E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 5.9E-73 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 SUPERFAMILY SSF82693 41 130 1.78E-23 T 28-03-2018 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 Gene3D G3DSA:3.30.70.1430 555 650 2.4E-11 T 28-03-2018 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 Gene3D G3DSA:3.30.70.1430 40 141 3.3E-25 T 28-03-2018 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 SUPERFAMILY SSF82866 290 489 3.27E-46 T 28-03-2018 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 SUPERFAMILY SSF82714 701 783 3.27E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 SUPERFAMILY SSF82693 553 650 1.92E-18 T 28-03-2018 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 Gene3D G3DSA:3.30.2090.10 180 267 3.4E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 SUPERFAMILY SSF82866 782 1008 4.32E-47 T 28-03-2018 A6A12_RS14005 4450173c93156190a0e1088d432cbaed 1040 Gene3D G3DSA:1.20.1640.10 791 1008 8.2E-43 T 28-03-2018 A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 Gene3D G3DSA:1.10.287.130 315 374 1.1E-15 T 28-03-2018 A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 SUPERFAMILY SSF55890 322 391 3.27E-9 T 28-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 Pfam PF00989 PAS fold 216 266 1.3E-5 T 28-03-2018 IPR013767 PAS fold GO:0006355 A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 320 371 1.7E-8 T 28-03-2018 A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 SUPERFAMILY SSF55785 217 306 1.2E-10 T 28-03-2018 IPR000014 PAS domain A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 Gene3D G3DSA:3.30.450.20 31 164 8.8E-21 T 28-03-2018 A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 SUPERFAMILY SSF103190 39 168 1.37E-31 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 SUPERFAMILY SSF55874 386 534 1.44E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 Gene3D G3DSA:3.30.565.10 375 538 8.9E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 Pfam PF17203 Single cache domain 3 41 168 4.6E-17 T 28-03-2018 IPR033463 Single cache domain 3 A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 PRINTS PR00344 Bacterial sensor protein C-terminal signature 466 480 3.3E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 PRINTS PR00344 Bacterial sensor protein C-terminal signature 521 534 3.3E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 515 3.3E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 SMART SM00387 418 537 6.7E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 422 536 1.1E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS07920 b2645c5638059618e5eaafb0075cb60d 539 Gene3D G3DSA:3.30.450.20 215 314 1.8E-8 T 28-03-2018 A6A12_RS07985 b9a5d21a3af6306ff89584156ab07569 289 Pfam PF03466 LysR substrate binding domain 88 287 2.5E-44 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS07985 b9a5d21a3af6306ff89584156ab07569 289 Gene3D G3DSA:1.10.10.10 1 83 2.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS07985 b9a5d21a3af6306ff89584156ab07569 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS07985 b9a5d21a3af6306ff89584156ab07569 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS07985 b9a5d21a3af6306ff89584156ab07569 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS07985 b9a5d21a3af6306ff89584156ab07569 289 SUPERFAMILY SSF46785 1 110 5.03E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS07985 b9a5d21a3af6306ff89584156ab07569 289 Gene3D G3DSA:3.40.190.10 87 176 1.9E-22 T 28-03-2018 A6A12_RS07985 b9a5d21a3af6306ff89584156ab07569 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 5.1E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS07985 b9a5d21a3af6306ff89584156ab07569 289 Gene3D G3DSA:3.40.190.10 177 260 6.1E-16 T 28-03-2018 A6A12_RS07985 b9a5d21a3af6306ff89584156ab07569 289 SUPERFAMILY SSF53850 89 288 4.19E-39 T 28-03-2018 A6A12_RS07070 61c6f4adbc4dab99c26627467ad312d0 100 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 15 99 8.8E-14 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A6A12_RS07070 61c6f4adbc4dab99c26627467ad312d0 100 Gene3D G3DSA:1.10.1370.10 7 98 3.3E-14 T 28-03-2018 A6A12_RS07070 61c6f4adbc4dab99c26627467ad312d0 100 SUPERFAMILY SSF55486 10 100 3.17E-18 T 28-03-2018 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 447 465 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 447 462 4.2E-30 T 28-03-2018 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 293 312 4.2E-30 T 28-03-2018 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 500 512 4.2E-30 T 28-03-2018 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 464 479 4.2E-30 T 28-03-2018 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 Gene3D G3DSA:1.10.274.10 24 131 7.2E-34 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 Gene3D G3DSA:3.20.20.60 255 573 2.0E-102 T 28-03-2018 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 PIRSF PIRSF000732 1 574 2.7E-219 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 Pfam PF00391 PEP-utilising enzyme, mobile domain 152 222 3.0E-20 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 184 195 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 SUPERFAMILY SSF52009 125 245 7.46E-35 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 SUPERFAMILY SSF47831 24 143 4.05E-32 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 Gene3D G3DSA:3.50.30.10 132 254 1.4E-27 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 SUPERFAMILY SSF51621 249 549 9.42E-109 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 Pfam PF05524 PEP-utilising enzyme, N-terminal 4 126 1.7E-30 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 2 565 1.1E-244 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 A6A12_RS04435 4c817a45d11c49cf59478d01a3f40f65 574 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 250 541 3.1E-124 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A6A12_RS13410 fb5b3b46e5c41b2e7f5ebb1a403440ee 292 SUPERFAMILY SSF53448 1 285 3.9E-94 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13410 fb5b3b46e5c41b2e7f5ebb1a403440ee 292 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 4.5E-160 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 A6A12_RS13410 fb5b3b46e5c41b2e7f5ebb1a403440ee 292 Gene3D G3DSA:3.90.550.10 1 292 1.0E-74 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13410 fb5b3b46e5c41b2e7f5ebb1a403440ee 292 Pfam PF00483 Nucleotidyl transferase 2 238 1.1E-73 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A6A12_RS04555 f77acd12c7a6e9f85ad99451138a1d49 528 SUPERFAMILY SSF51735 387 517 7.88E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS04555 f77acd12c7a6e9f85ad99451138a1d49 528 Pfam PF00999 Sodium/hydrogen exchanger family 3 348 3.3E-33 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A6A12_RS04555 f77acd12c7a6e9f85ad99451138a1d49 528 Pfam PF02254 TrkA-N domain 388 504 7.7E-18 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A6A12_RS04555 f77acd12c7a6e9f85ad99451138a1d49 528 Gene3D G3DSA:3.40.50.720 379 527 3.6E-14 T 28-03-2018 A6A12_RS10885 11ce8b228436f470cac61a323c76964f 280 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 238 264 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 A6A12_RS10885 11ce8b228436f470cac61a323c76964f 280 Pfam PF01148 Cytidylyltransferase family 2 280 4.3E-69 T 28-03-2018 A6A12_RS12275 c826b93d749f1dcefe04df64a0d87d6d 238 SUPERFAMILY SSF52540 9 228 2.57E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12275 c826b93d749f1dcefe04df64a0d87d6d 238 Pfam PF00005 ABC transporter 34 184 2.7E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS12275 c826b93d749f1dcefe04df64a0d87d6d 238 SMART SM00382 39 232 8.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS12275 c826b93d749f1dcefe04df64a0d87d6d 238 Gene3D G3DSA:3.40.50.300 9 236 7.3E-53 T 28-03-2018 A6A12_RS12085 72a64df317836ccef8ca4d6c77eeec66 319 Gene3D G3DSA:3.30.565.10 166 318 1.3E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS12085 72a64df317836ccef8ca4d6c77eeec66 319 Gene3D G3DSA:1.10.287.130 49 163 1.1E-7 T 28-03-2018 A6A12_RS12085 72a64df317836ccef8ca4d6c77eeec66 319 SMART SM00387 208 319 1.0E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS12085 72a64df317836ccef8ca4d6c77eeec66 319 SUPERFAMILY SSF55874 158 318 1.7E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS12085 72a64df317836ccef8ca4d6c77eeec66 319 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 210 317 2.0E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS12085 72a64df317836ccef8ca4d6c77eeec66 319 PRINTS PR00344 Bacterial sensor protein C-terminal signature 267 277 2.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS12085 72a64df317836ccef8ca4d6c77eeec66 319 PRINTS PR00344 Bacterial sensor protein C-terminal signature 249 263 2.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS12085 72a64df317836ccef8ca4d6c77eeec66 319 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 317 2.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS12085 72a64df317836ccef8ca4d6c77eeec66 319 PRINTS PR00344 Bacterial sensor protein C-terminal signature 280 298 2.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS11150 979be9ff1ae3409440328985b888f09c 367 SUPERFAMILY SSF50685 20 350 4.19E-101 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain A6A12_RS11150 979be9ff1ae3409440328985b888f09c 367 Pfam PF06725 3D domain 272 348 3.6E-21 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 A6A12_RS11150 979be9ff1ae3409440328985b888f09c 367 SMART SM00925 119 252 3.8E-62 T 28-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 A6A12_RS11150 979be9ff1ae3409440328985b888f09c 367 Gene3D G3DSA:2.40.240.50 50 253 8.4E-57 T 28-03-2018 A6A12_RS11150 979be9ff1ae3409440328985b888f09c 367 Pfam PF03562 MltA specific insert domain 69 251 5.1E-36 T 28-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 A6A12_RS07405 0ddc02e0c74bc9ef950af1fd8b2df9dc 292 Pfam PF01739 CheR methyltransferase, SAM binding domain 97 273 1.3E-51 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal A6A12_RS07405 0ddc02e0c74bc9ef950af1fd8b2df9dc 292 SUPERFAMILY SSF47757 17 96 2.62E-16 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal A6A12_RS07405 0ddc02e0c74bc9ef950af1fd8b2df9dc 292 Gene3D G3DSA:3.40.50.150 96 288 6.1E-45 T 28-03-2018 A6A12_RS07405 0ddc02e0c74bc9ef950af1fd8b2df9dc 292 Gene3D G3DSA:1.10.155.10 17 95 7.5E-16 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal A6A12_RS07405 0ddc02e0c74bc9ef950af1fd8b2df9dc 292 PRINTS PR00996 Glutamate methyltransferase family signature 125 145 1.1E-38 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A6A12_RS07405 0ddc02e0c74bc9ef950af1fd8b2df9dc 292 PRINTS PR00996 Glutamate methyltransferase family signature 227 241 1.1E-38 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A6A12_RS07405 0ddc02e0c74bc9ef950af1fd8b2df9dc 292 PRINTS PR00996 Glutamate methyltransferase family signature 90 102 1.1E-38 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A6A12_RS07405 0ddc02e0c74bc9ef950af1fd8b2df9dc 292 PRINTS PR00996 Glutamate methyltransferase family signature 156 172 1.1E-38 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A6A12_RS07405 0ddc02e0c74bc9ef950af1fd8b2df9dc 292 PRINTS PR00996 Glutamate methyltransferase family signature 47 60 1.1E-38 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A6A12_RS07405 0ddc02e0c74bc9ef950af1fd8b2df9dc 292 PRINTS PR00996 Glutamate methyltransferase family signature 246 269 1.1E-38 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A6A12_RS07405 0ddc02e0c74bc9ef950af1fd8b2df9dc 292 SMART SM00138 25 288 2.4E-66 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A6A12_RS07405 0ddc02e0c74bc9ef950af1fd8b2df9dc 292 SUPERFAMILY SSF53335 97 273 3.96E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS07405 0ddc02e0c74bc9ef950af1fd8b2df9dc 292 Pfam PF03705 CheR methyltransferase, all-alpha domain 26 75 7.5E-15 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal A6A12_RS07405 0ddc02e0c74bc9ef950af1fd8b2df9dc 292 PIRSF PIRSF000410 5 289 8.8E-88 T 28-03-2018 IPR026024 Chemotaxis protein methyltransferase CheR A6A12_RS10225 526b3a7b7215a9d5b363ac5c2fccbb5b 103 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 1 103 16.89 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A6A12_RS10225 526b3a7b7215a9d5b363ac5c2fccbb5b 103 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 17 102 2.7E-19 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A6A12_RS10225 526b3a7b7215a9d5b363ac5c2fccbb5b 103 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 32 48 4.7E-13 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A6A12_RS10225 526b3a7b7215a9d5b363ac5c2fccbb5b 103 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 67 83 4.7E-13 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A6A12_RS10225 526b3a7b7215a9d5b363ac5c2fccbb5b 103 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 88 101 4.7E-13 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A6A12_RS10225 526b3a7b7215a9d5b363ac5c2fccbb5b 103 Pfam PF02049 Flagellar hook-basal body complex protein FliE 18 103 2.7E-30 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 A6A12_RS01630 ce86e8e80c66afa0d694419dc8c31e77 166 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 31 6.1E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS01630 ce86e8e80c66afa0d694419dc8c31e77 166 SUPERFAMILY SSF54523 11 120 1.26E-13 T 28-03-2018 A6A12_RS01630 ce86e8e80c66afa0d694419dc8c31e77 166 Gene3D G3DSA:3.30.700.10 11 162 3.6E-14 T 28-03-2018 A6A12_RS01630 ce86e8e80c66afa0d694419dc8c31e77 166 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 30 1.9E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS01165 b80b6ae14bdcdf675527c32d58140313 142 Gene3D G3DSA:3.30.1550.10 3 72 2.9E-33 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal A6A12_RS01165 b80b6ae14bdcdf675527c32d58140313 142 SUPERFAMILY SSF46906 68 141 1.02E-23 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A6A12_RS01165 b80b6ae14bdcdf675527c32d58140313 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 3.0E-15 T 28-03-2018 A6A12_RS01165 b80b6ae14bdcdf675527c32d58140313 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 3.4E-63 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01165 b80b6ae14bdcdf675527c32d58140313 142 SMART SM00649 9 141 2.0E-79 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A6A12_RS01165 b80b6ae14bdcdf675527c32d58140313 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 1.1E-21 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A6A12_RS01165 b80b6ae14bdcdf675527c32d58140313 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS01165 b80b6ae14bdcdf675527c32d58140313 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 1.4E-28 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal A6A12_RS01165 b80b6ae14bdcdf675527c32d58140313 142 SUPERFAMILY SSF54747 3 73 2.22E-29 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal A6A12_RS01165 b80b6ae14bdcdf675527c32d58140313 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 29.656 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A6A12_RS01165 b80b6ae14bdcdf675527c32d58140313 142 Gene3D G3DSA:1.10.10.250 73 141 4.5E-21 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A6A12_RS02615 66d8b5e568038f8518cf14effeed7d8f 295 PIRSF PIRSF006250 16 295 7.0E-101 T 28-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 A6A12_RS02615 66d8b5e568038f8518cf14effeed7d8f 295 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 130 293 1.7E-56 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A6A12_RS02615 66d8b5e568038f8518cf14effeed7d8f 295 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 41 127 2.0E-28 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A6A12_RS02615 66d8b5e568038f8518cf14effeed7d8f 295 Gene3D G3DSA:3.20.20.70 155 284 2.8E-38 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS02615 66d8b5e568038f8518cf14effeed7d8f 295 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 26 294 3.8E-94 T 28-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 A6A12_RS02615 66d8b5e568038f8518cf14effeed7d8f 295 Gene3D G3DSA:3.90.1170.20 7 154 1.8E-45 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A6A12_RS02615 66d8b5e568038f8518cf14effeed7d8f 295 SUPERFAMILY SSF54675 13 128 4.71E-34 T 28-03-2018 A6A12_RS02615 66d8b5e568038f8518cf14effeed7d8f 295 SUPERFAMILY SSF51690 130 294 1.1E-58 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A6A12_RS02070 852563a59551290dfe5d2a02668c1dd3 698 Gene3D G3DSA:3.55.50.10 105 196 4.8E-27 T 28-03-2018 A6A12_RS02070 852563a59551290dfe5d2a02668c1dd3 698 SUPERFAMILY SSF69349 448 629 7.85E-47 T 28-03-2018 A6A12_RS02070 852563a59551290dfe5d2a02668c1dd3 698 Pfam PF05954 Phage late control gene D protein (GPD) 42 335 1.6E-74 T 28-03-2018 A6A12_RS02070 852563a59551290dfe5d2a02668c1dd3 698 SUPERFAMILY SSF69279 194 371 6.12E-44 T 28-03-2018 A6A12_RS02070 852563a59551290dfe5d2a02668c1dd3 698 SUPERFAMILY SSF69279 6 192 1.25E-48 T 28-03-2018 A6A12_RS02070 852563a59551290dfe5d2a02668c1dd3 698 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 6 527 1.6E-186 T 28-03-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset A6A12_RS02070 852563a59551290dfe5d2a02668c1dd3 698 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 43 509 8.2E-131 T 28-03-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein A6A12_RS02070 852563a59551290dfe5d2a02668c1dd3 698 SUPERFAMILY SSF69255 370 457 1.07E-32 T 28-03-2018 A6A12_RS02070 852563a59551290dfe5d2a02668c1dd3 698 Gene3D G3DSA:2.40.50.230 377 458 2.7E-34 T 28-03-2018 IPR006531 Gp5 N-terminal A6A12_RS09760 6feccc7744f300cfd3e4f4f772a89bbd 333 Hamap MF_00730 Nucleoid-associated protein YejK [yejK]. 3 332 46.005 T 28-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 A6A12_RS09760 6feccc7744f300cfd3e4f4f772a89bbd 333 Pfam PF04245 37-kD nucleoid-associated bacterial protein 9 326 2.0E-96 T 28-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 A6A12_RS09575 5560b1de3d341806116339028c4f7fda 194 ProDom PD353566 UPF0207 HYDROLASE HD PHOSPHOHYDROLASE METAL-DEPENDENT SUBDOMAIN YFBR PHOSPHOHYDROLASE NUCLEOTIDE-BINDING NUCLEOSIDE 80 184 2.0E-35 T 28-03-2018 A6A12_RS09575 5560b1de3d341806116339028c4f7fda 194 Hamap MF_01100 5'-deoxynucleotidase YfbR [yfbR]. 3 194 45.281 T 28-03-2018 IPR022971 5'-deoxynucleotidase YfbR KEGG: 00240+3.1.3.89 A6A12_RS09575 5560b1de3d341806116339028c4f7fda 194 Pfam PF13023 HD domain 11 156 7.7E-14 T 28-03-2018 IPR006674 HD domain A6A12_RS09575 5560b1de3d341806116339028c4f7fda 194 Gene3D G3DSA:1.10.3210.10 1 194 4.5E-48 T 28-03-2018 A6A12_RS09575 5560b1de3d341806116339028c4f7fda 194 SUPERFAMILY SSF109604 4 184 1.22E-42 T 28-03-2018 A6A12_RS09575 5560b1de3d341806116339028c4f7fda 194 SMART SM00471 26 151 1.5E-7 T 28-03-2018 IPR003607 HD/PDEase domain A6A12_RS10040 d4191e7f79f4b450b36132781b9ec4f8 251 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 8 238 5.0E-61 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A6A12_RS10040 d4191e7f79f4b450b36132781b9ec4f8 251 Gene3D G3DSA:3.40.1390.30 1 109 1.4E-28 T 28-03-2018 A6A12_RS10040 d4191e7f79f4b450b36132781b9ec4f8 251 Gene3D G3DSA:3.40.1390.30 110 222 1.6E-32 T 28-03-2018 A6A12_RS10040 d4191e7f79f4b450b36132781b9ec4f8 251 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 2 250 5.7E-69 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A6A12_RS10040 d4191e7f79f4b450b36132781b9ec4f8 251 SUPERFAMILY SSF102705 1 250 3.27E-83 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A6A12_RS12705 a0af040472ffc12c99e3e9256cf98cbf 336 Pfam PF11104 Type IV pilus assembly protein PilM; 8 326 1.5E-48 T 28-03-2018 IPR005883 Type IV pilus assembly protein PilM A6A12_RS12705 a0af040472ffc12c99e3e9256cf98cbf 336 Gene3D G3DSA:3.30.420.40 1 165 3.8E-19 T 28-03-2018 A6A12_RS12705 a0af040472ffc12c99e3e9256cf98cbf 336 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 3 327 9.3E-93 T 28-03-2018 IPR005883 Type IV pilus assembly protein PilM A6A12_RS12705 a0af040472ffc12c99e3e9256cf98cbf 336 SUPERFAMILY SSF53067 5 165 1.13E-5 T 28-03-2018 A6A12_RS12705 a0af040472ffc12c99e3e9256cf98cbf 336 Gene3D G3DSA:3.30.420.40 177 292 2.8E-5 T 28-03-2018 A6A12_RS12705 a0af040472ffc12c99e3e9256cf98cbf 336 PIRSF PIRSF019169 1 328 2.8E-81 T 28-03-2018 IPR005883 Type IV pilus assembly protein PilM A6A12_RS12705 a0af040472ffc12c99e3e9256cf98cbf 336 SUPERFAMILY SSF53067 185 324 2.71E-5 T 28-03-2018 A6A12_RS01790 9a497d0a31ef5b9440fa5b6de47fad8f 271 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 1 269 48.169 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 A6A12_RS01790 9a497d0a31ef5b9440fa5b6de47fad8f 271 SUPERFAMILY SSF56300 4 255 3.38E-54 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A6A12_RS01790 9a497d0a31ef5b9440fa5b6de47fad8f 271 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 2 270 1.9E-120 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 A6A12_RS01790 9a497d0a31ef5b9440fa5b6de47fad8f 271 Gene3D G3DSA:3.60.21.10 3 270 5.6E-47 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A6A12_RS01790 9a497d0a31ef5b9440fa5b6de47fad8f 271 Pfam PF00149 Calcineurin-like phosphoesterase 5 151 3.6E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A6A12_RS01790 9a497d0a31ef5b9440fa5b6de47fad8f 271 PIRSF PIRSF000903 1 271 1.3E-119 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 A6A12_RS04985 b8a6d15fef5b320038b907d505129ee4 667 Gene3D G3DSA:3.50.50.60 474 620 1.4E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS04985 b8a6d15fef5b320038b907d505129ee4 667 SUPERFAMILY SSF51971 332 516 5.49E-40 T 28-03-2018 A6A12_RS04985 b8a6d15fef5b320038b907d505129ee4 667 SUPERFAMILY SSF51395 2 361 3.67E-106 T 28-03-2018 A6A12_RS04985 b8a6d15fef5b320038b907d505129ee4 667 Gene3D G3DSA:3.40.50.720 363 473 5.7E-21 T 28-03-2018 A6A12_RS04985 b8a6d15fef5b320038b907d505129ee4 667 SUPERFAMILY SSF51905 523 625 1.5E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS04985 b8a6d15fef5b320038b907d505129ee4 667 SUPERFAMILY SSF51905 372 423 1.5E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS04985 b8a6d15fef5b320038b907d505129ee4 667 Gene3D G3DSA:3.20.20.70 1 362 5.8E-107 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS04985 b8a6d15fef5b320038b907d505129ee4 667 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 375 626 3.0E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS04985 b8a6d15fef5b320038b907d505129ee4 667 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 328 2.5E-81 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A6A12_RS04985 b8a6d15fef5b320038b907d505129ee4 667 PRINTS PR00419 Adrenodoxin reductase family signature 375 397 8.0E-10 T 28-03-2018 A6A12_RS04985 b8a6d15fef5b320038b907d505129ee4 667 PRINTS PR00419 Adrenodoxin reductase family signature 398 411 8.0E-10 T 28-03-2018 A6A12_RS09390 286fab81ac6a4d4a1b44e1949ff348d4 531 Gene3D G3DSA:3.30.565.10 370 531 2.7E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09390 286fab81ac6a4d4a1b44e1949ff348d4 531 SUPERFAMILY SSF55874 355 524 4.85E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09390 286fab81ac6a4d4a1b44e1949ff348d4 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 525 8.8E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS09390 286fab81ac6a4d4a1b44e1949ff348d4 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 481 8.8E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS09390 286fab81ac6a4d4a1b44e1949ff348d4 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 467 8.8E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS09390 286fab81ac6a4d4a1b44e1949ff348d4 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 488 506 8.8E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS09390 286fab81ac6a4d4a1b44e1949ff348d4 531 SMART SM00387 416 528 2.8E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09390 286fab81ac6a4d4a1b44e1949ff348d4 531 SMART SM00388 299 366 3.2E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS09390 286fab81ac6a4d4a1b44e1949ff348d4 531 SUPERFAMILY SSF158472 214 264 7.59E-9 T 28-03-2018 A6A12_RS09390 286fab81ac6a4d4a1b44e1949ff348d4 531 SMART SM00304 214 266 3.4E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS09390 286fab81ac6a4d4a1b44e1949ff348d4 531 Pfam PF00672 HAMP domain 214 262 2.7E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS09390 286fab81ac6a4d4a1b44e1949ff348d4 531 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 417 527 7.7E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09390 286fab81ac6a4d4a1b44e1949ff348d4 531 Pfam PF00512 His Kinase A (phospho-acceptor) domain 300 364 9.3E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS09390 286fab81ac6a4d4a1b44e1949ff348d4 531 Gene3D G3DSA:1.10.287.130 289 362 5.2E-17 T 28-03-2018 A6A12_RS09390 286fab81ac6a4d4a1b44e1949ff348d4 531 SUPERFAMILY SSF47384 284 364 1.47E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS12775 d09825693d2aeb7bb3979db047472b26 342 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 14 169 1.4E-45 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A6A12_RS12775 d09825693d2aeb7bb3979db047472b26 342 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 198 219 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A6A12_RS12775 d09825693d2aeb7bb3979db047472b26 342 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 190 328 6.1E-52 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A6A12_RS12775 d09825693d2aeb7bb3979db047472b26 342 Gene3D G3DSA:1.10.1040.10 199 342 1.6E-53 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A6A12_RS12775 d09825693d2aeb7bb3979db047472b26 342 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 16 33 4.5E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A6A12_RS12775 d09825693d2aeb7bb3979db047472b26 342 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 183 207 4.5E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A6A12_RS12775 d09825693d2aeb7bb3979db047472b26 342 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 142 162 4.5E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A6A12_RS12775 d09825693d2aeb7bb3979db047472b26 342 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 66 93 4.5E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A6A12_RS12775 d09825693d2aeb7bb3979db047472b26 342 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 208 232 4.5E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A6A12_RS12775 d09825693d2aeb7bb3979db047472b26 342 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 248 265 4.5E-43 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A6A12_RS12775 d09825693d2aeb7bb3979db047472b26 342 SUPERFAMILY SSF48179 189 341 1.03E-55 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A6A12_RS12775 d09825693d2aeb7bb3979db047472b26 342 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 12 332 36.515 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A6A12_RS12775 d09825693d2aeb7bb3979db047472b26 342 SUPERFAMILY SSF51735 13 188 9.92E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS12775 d09825693d2aeb7bb3979db047472b26 342 PIRSF PIRSF000114 9 342 2.6E-95 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 A6A12_RS12775 d09825693d2aeb7bb3979db047472b26 342 Gene3D G3DSA:3.40.50.720 10 188 9.4E-30 T 28-03-2018 A6A12_RS11330 8b0ff7c532bf51b3a990b17693ad56d6 257 Pfam PF03883 Peroxide stress protein YaaA 1 243 1.8E-90 T 28-03-2018 IPR005583 Peroxide stress protein YaaA A6A12_RS11330 8b0ff7c532bf51b3a990b17693ad56d6 257 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 37.889 T 28-03-2018 IPR005583 Peroxide stress protein YaaA A6A12_RS08925 b27f9ff8af3be08929462463b55c02d5 256 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS08925 b27f9ff8af3be08929462463b55c02d5 256 SMART SM00382 31 229 2.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS08925 b27f9ff8af3be08929462463b55c02d5 256 PIRSF PIRSF039085 3 256 6.3E-118 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A6A12_RS08925 b27f9ff8af3be08929462463b55c02d5 256 SUPERFAMILY SSF52540 7 251 5.32E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS08925 b27f9ff8af3be08929462463b55c02d5 256 Pfam PF00005 ABC transporter 22 181 6.8E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS08925 b27f9ff8af3be08929462463b55c02d5 256 Gene3D G3DSA:3.40.50.300 2 255 6.9E-69 T 28-03-2018 A6A12_RS11740 9356bed9c95aab535bef54641dcba0b8 532 Gene3D G3DSA:3.40.50.300 17 197 3.5E-12 T 28-03-2018 A6A12_RS11740 9356bed9c95aab535bef54641dcba0b8 532 Pfam PF01471 Putative peptidoglycan binding domain 458 513 1.6E-6 T 28-03-2018 IPR002477 Peptidoglycan binding-like A6A12_RS11740 9356bed9c95aab535bef54641dcba0b8 532 Gene3D G3DSA:3.90.70.10 333 446 5.4E-17 T 28-03-2018 A6A12_RS11740 9356bed9c95aab535bef54641dcba0b8 532 SMART SM00382 42 195 7.2E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS11740 9356bed9c95aab535bef54641dcba0b8 532 Pfam PF03412 Peptidase C39 family 371 441 1.5E-4 T 28-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 A6A12_RS11740 9356bed9c95aab535bef54641dcba0b8 532 SUPERFAMILY SSF47090 449 521 8.89E-10 T 28-03-2018 IPR002477 Peptidoglycan binding-like A6A12_RS11740 9356bed9c95aab535bef54641dcba0b8 532 SUPERFAMILY SSF52540 5 264 8.92E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11740 9356bed9c95aab535bef54641dcba0b8 532 Pfam PF13401 AAA domain 42 171 7.4E-23 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS11740 9356bed9c95aab535bef54641dcba0b8 532 Gene3D G3DSA:1.10.101.10 447 523 1.2E-10 T 28-03-2018 IPR002477 Peptidoglycan binding-like A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 SUPERFAMILY SSF47384 120 191 5.89E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 Gene3D G3DSA:3.30.450.20 8 118 9.1E-9 T 28-03-2018 A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 Pfam PF13188 PAS domain 21 73 1.2E-7 T 28-03-2018 IPR000014 PAS domain A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 Pfam PF00512 His Kinase A (phospho-acceptor) domain 125 189 1.5E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 SMART SM00387 234 340 6.1E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 Gene3D G3DSA:3.30.565.10 192 351 5.7E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 SMART SM00091 21 84 7.8E-5 T 28-03-2018 IPR000014 PAS domain A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 Gene3D G3DSA:1.10.287.130 119 187 2.5E-6 T 28-03-2018 A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 PRINTS PR00344 Bacterial sensor protein C-terminal signature 289 299 2.0E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 285 2.0E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 PRINTS PR00344 Bacterial sensor protein C-terminal signature 300 318 2.0E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 337 2.0E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 SUPERFAMILY SSF55785 21 88 1.11E-7 T 28-03-2018 IPR000014 PAS domain A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 SUPERFAMILY SSF55874 180 338 5.24E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 237 339 1.8E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS10235 7b2bd07ec830f75edc8f2cc614adb022 352 SMART SM00388 125 191 5.5E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS06560 9c2e36c97d2c7ddd7f3d20417bf0a126 277 PIRSF PIRSF012524 1 277 2.2E-99 T 28-03-2018 IPR014464 Conserved virulence factor B A6A12_RS06560 9c2e36c97d2c7ddd7f3d20417bf0a126 277 SMART SM00316 69 132 0.0025 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS06560 9c2e36c97d2c7ddd7f3d20417bf0a126 277 SMART SM00316 145 207 10.0 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS06560 9c2e36c97d2c7ddd7f3d20417bf0a126 277 SMART SM00316 3 64 3.7 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS06560 9c2e36c97d2c7ddd7f3d20417bf0a126 277 Gene3D G3DSA:1.10.10.10 218 276 3.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS06560 9c2e36c97d2c7ddd7f3d20417bf0a126 277 Pfam PF13509 S1 domain 71 132 1.3E-6 T 28-03-2018 A6A12_RS06560 9c2e36c97d2c7ddd7f3d20417bf0a126 277 Pfam PF13509 S1 domain 4 63 2.8E-21 T 28-03-2018 A6A12_RS06560 9c2e36c97d2c7ddd7f3d20417bf0a126 277 Gene3D G3DSA:2.40.50.140 1 57 0.022 T 28-03-2018 A6A12_RS06560 9c2e36c97d2c7ddd7f3d20417bf0a126 277 Gene3D G3DSA:2.40.50.140 58 209 1.0E-15 T 28-03-2018 A6A12_RS02820 7bffd367e868c665f3fe4a2dfd4d098a 575 SUPERFAMILY SSF48208 78 561 1.47E-86 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 A6A12_RS02820 7bffd367e868c665f3fe4a2dfd4d098a 575 Gene3D G3DSA:2.60.40.10 2 92 3.6E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS02820 7bffd367e868c665f3fe4a2dfd4d098a 575 Pfam PF00759 Glycosyl hydrolase family 9 98 503 3.2E-21 T 28-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A6A12_RS02820 7bffd367e868c665f3fe4a2dfd4d098a 575 Gene3D G3DSA:1.50.10.10 96 563 5.2E-64 T 28-03-2018 A6A12_RS02820 7bffd367e868c665f3fe4a2dfd4d098a 575 Pfam PF02927 Cellulase N-terminal ig-like domain 5 83 3.3E-11 T 28-03-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 A6A12_RS02820 7bffd367e868c665f3fe4a2dfd4d098a 575 SUPERFAMILY SSF81296 2 90 1.61E-14 T 28-03-2018 IPR014756 Immunoglobulin E-set A6A12_RS07120 6a185702cda70a2f9eafae34718eaaa7 237 SUPERFAMILY SSF53098 42 222 1.24E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS07120 6a185702cda70a2f9eafae34718eaaa7 237 Pfam PF00929 Exonuclease 53 214 3.3E-10 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS07120 6a185702cda70a2f9eafae34718eaaa7 237 SMART SM00479 51 223 2.8E-12 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS07120 6a185702cda70a2f9eafae34718eaaa7 237 Gene3D G3DSA:3.30.420.10 48 228 7.5E-23 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS00950 fc50dfd0ec13d73c1e81274bf87eb51f 160 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 120 136 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A6A12_RS00950 fc50dfd0ec13d73c1e81274bf87eb51f 160 SUPERFAMILY SSF46557 3 78 1.44E-25 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A6A12_RS00950 fc50dfd0ec13d73c1e81274bf87eb51f 160 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 6.4E-23 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A6A12_RS00950 fc50dfd0ec13d73c1e81274bf87eb51f 160 SUPERFAMILY SSF54534 80 156 1.44E-19 T 28-03-2018 A6A12_RS00950 fc50dfd0ec13d73c1e81274bf87eb51f 160 Hamap MF_00930 Transcription elongation factor GreB [greB]. 1 157 49.963 T 28-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 A6A12_RS00950 fc50dfd0ec13d73c1e81274bf87eb51f 160 PIRSF PIRSF006092 2 158 3.6E-42 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 A6A12_RS00950 fc50dfd0ec13d73c1e81274bf87eb51f 160 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A6A12_RS00950 fc50dfd0ec13d73c1e81274bf87eb51f 160 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 81 156 1.0E-22 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A6A12_RS00950 fc50dfd0ec13d73c1e81274bf87eb51f 160 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 2 158 1.9E-71 T 28-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 A6A12_RS00950 fc50dfd0ec13d73c1e81274bf87eb51f 160 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 155 26.418 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 A6A12_RS00950 fc50dfd0ec13d73c1e81274bf87eb51f 160 Gene3D G3DSA:1.10.287.180 3 75 3.1E-25 T 28-03-2018 A6A12_RS00950 fc50dfd0ec13d73c1e81274bf87eb51f 160 Gene3D G3DSA:3.10.50.30 76 160 6.1E-24 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A6A12_RS10255 d37fbb59568e3fc1d632fd1de82907a1 666 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 430 655 7.8E-53 T 28-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 A6A12_RS10255 d37fbb59568e3fc1d632fd1de82907a1 666 Gene3D G3DSA:1.20.1420.10 189 314 4.8E-4 T 28-03-2018 A6A12_RS10255 d37fbb59568e3fc1d632fd1de82907a1 666 Pfam PF07196 Flagellin hook IN motif 125 177 2.3E-8 T 28-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 A6A12_RS10255 d37fbb59568e3fc1d632fd1de82907a1 666 Gene3D G3DSA:1.20.120.330 345 663 0.22 T 28-03-2018 A6A12_RS10255 d37fbb59568e3fc1d632fd1de82907a1 666 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 10 107 5.3E-20 T 28-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 A6A12_RS11655 cd2394336b16fd30f5d486729b5617ef 354 Pfam PF13365 Trypsin-like peptidase domain 82 216 4.4E-32 T 28-03-2018 A6A12_RS11655 cd2394336b16fd30f5d486729b5617ef 354 Pfam PF13180 PDZ domain 257 347 6.3E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS11655 cd2394336b16fd30f5d486729b5617ef 354 Gene3D G3DSA:2.40.10.10 132 247 2.5E-34 T 28-03-2018 A6A12_RS11655 cd2394336b16fd30f5d486729b5617ef 354 SUPERFAMILY SSF50494 46 254 9.85E-60 T 28-03-2018 IPR009003 Peptidase S1, PA clan A6A12_RS11655 cd2394336b16fd30f5d486729b5617ef 354 Gene3D G3DSA:2.30.42.10 255 354 4.4E-22 T 28-03-2018 A6A12_RS11655 cd2394336b16fd30f5d486729b5617ef 354 SMART SM00228 257 339 1.6E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS11655 cd2394336b16fd30f5d486729b5617ef 354 TIGRFAM TIGR02038 protease_degS: periplasmic serine peptidase DegS 2 351 2.2E-165 T 28-03-2018 IPR011783 Peptidase S1C, DegS GO:0004252|GO:0006508 A6A12_RS11655 cd2394336b16fd30f5d486729b5617ef 354 SUPERFAMILY SSF50156 240 347 9.2E-21 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS11655 cd2394336b16fd30f5d486729b5617ef 354 Gene3D G3DSA:2.40.10.10 29 131 7.0E-31 T 28-03-2018 A6A12_RS11655 cd2394336b16fd30f5d486729b5617ef 354 PRINTS PR00834 HtrA/DegQ protease family signature 297 309 5.6E-46 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A6A12_RS11655 cd2394336b16fd30f5d486729b5617ef 354 PRINTS PR00834 HtrA/DegQ protease family signature 209 226 5.6E-46 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A6A12_RS11655 cd2394336b16fd30f5d486729b5617ef 354 PRINTS PR00834 HtrA/DegQ protease family signature 112 132 5.6E-46 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A6A12_RS11655 cd2394336b16fd30f5d486729b5617ef 354 PRINTS PR00834 HtrA/DegQ protease family signature 91 103 5.6E-46 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A6A12_RS11655 cd2394336b16fd30f5d486729b5617ef 354 PRINTS PR00834 HtrA/DegQ protease family signature 152 176 5.6E-46 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A6A12_RS11655 cd2394336b16fd30f5d486729b5617ef 354 PRINTS PR00834 HtrA/DegQ protease family signature 187 204 5.6E-46 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 A6A12_RS10445 8ea47b2748efd94927d46f7cbfc7f558 623 Pfam PF00672 HAMP domain 294 342 4.0E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS10445 8ea47b2748efd94927d46f7cbfc7f558 623 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 488 517 5.1E-23 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS10445 8ea47b2748efd94927d46f7cbfc7f558 623 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 382 411 5.1E-23 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS10445 8ea47b2748efd94927d46f7cbfc7f558 623 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 459 486 5.1E-23 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS10445 8ea47b2748efd94927d46f7cbfc7f558 623 Pfam PF02743 Cache domain 47 254 4.6E-30 T 28-03-2018 IPR033479 Double Cache domain 1 A6A12_RS10445 8ea47b2748efd94927d46f7cbfc7f558 623 SMART SM00283 361 622 1.3E-75 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS10445 8ea47b2748efd94927d46f7cbfc7f558 623 Gene3D G3DSA:1.10.287.950 397 623 8.8E-50 T 28-03-2018 A6A12_RS10445 8ea47b2748efd94927d46f7cbfc7f558 623 Gene3D G3DSA:1.10.287.950 296 396 7.0E-5 T 28-03-2018 A6A12_RS10445 8ea47b2748efd94927d46f7cbfc7f558 623 Gene3D G3DSA:3.30.450.20 160 271 2.8E-27 T 28-03-2018 A6A12_RS10445 8ea47b2748efd94927d46f7cbfc7f558 623 SMART SM00304 374 441 59.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS10445 8ea47b2748efd94927d46f7cbfc7f558 623 SMART SM00304 292 346 1.6E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS10445 8ea47b2748efd94927d46f7cbfc7f558 623 Gene3D G3DSA:3.30.450.20 62 159 6.0E-21 T 28-03-2018 A6A12_RS10445 8ea47b2748efd94927d46f7cbfc7f558 623 SUPERFAMILY SSF103190 55 184 1.05E-18 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A6A12_RS10445 8ea47b2748efd94927d46f7cbfc7f558 623 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 433 589 5.1E-43 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS10445 8ea47b2748efd94927d46f7cbfc7f558 623 SUPERFAMILY SSF58104 314 621 5.75E-74 T 28-03-2018 A6A12_RS05030 2a11eebee0bf7f43b84cefeb1f11c9a1 372 SUPERFAMILY SSF47819 296 371 7.41E-20 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 A6A12_RS05030 2a11eebee0bf7f43b84cefeb1f11c9a1 372 Pfam PF01612 3'-5' exonuclease 3 170 8.0E-38 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A6A12_RS05030 2a11eebee0bf7f43b84cefeb1f11c9a1 372 Pfam PF00570 HRDC domain 213 279 2.1E-7 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A6A12_RS05030 2a11eebee0bf7f43b84cefeb1f11c9a1 372 TIGRFAM TIGR01388 rnd: ribonuclease D 5 371 2.7E-148 T 28-03-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 A6A12_RS05030 2a11eebee0bf7f43b84cefeb1f11c9a1 372 Hamap MF_01899 Ribonuclease D [rnd]. 3 372 43.617 T 28-03-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 A6A12_RS05030 2a11eebee0bf7f43b84cefeb1f11c9a1 372 SUPERFAMILY SSF47819 193 301 5.23E-21 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 A6A12_RS05030 2a11eebee0bf7f43b84cefeb1f11c9a1 372 Gene3D G3DSA:1.10.150.80 195 293 1.2E-11 T 28-03-2018 A6A12_RS05030 2a11eebee0bf7f43b84cefeb1f11c9a1 372 SUPERFAMILY SSF53098 2 209 6.42E-69 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS05030 2a11eebee0bf7f43b84cefeb1f11c9a1 372 Gene3D G3DSA:3.30.420.10 1 194 7.1E-46 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS05030 2a11eebee0bf7f43b84cefeb1f11c9a1 372 SMART SM00474 3 171 7.3E-42 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A6A12_RS02980 5f1f2ce9ed378c86cd5852d5edf491e5 316 SUPERFAMILY SSF55120 9 248 7.77E-82 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS02980 5f1f2ce9ed378c86cd5852d5edf491e5 316 Gene3D G3DSA:3.30.2350.10 9 226 1.3E-79 T 28-03-2018 A6A12_RS02980 5f1f2ce9ed378c86cd5852d5edf491e5 316 SUPERFAMILY SSF88697 250 310 6.46E-15 T 28-03-2018 IPR015947 PUA-like domain A6A12_RS02980 5f1f2ce9ed378c86cd5852d5edf491e5 316 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 10 218 8.7E-87 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS02980 5f1f2ce9ed378c86cd5852d5edf491e5 316 Gene3D G3DSA:2.30.130.10 249 312 6.5E-17 T 28-03-2018 IPR002478 PUA domain GO:0003723 A6A12_RS02980 5f1f2ce9ed378c86cd5852d5edf491e5 316 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 251 308 9.4E-20 T 28-03-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS02980 5f1f2ce9ed378c86cd5852d5edf491e5 316 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 10 308 18.982 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS02980 5f1f2ce9ed378c86cd5852d5edf491e5 316 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 180 248 2.3E-24 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A6A12_RS02980 5f1f2ce9ed378c86cd5852d5edf491e5 316 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 32 179 2.1E-56 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A6A12_RS02430 58a2d93cca76c3797c7dcbe388c6370f 333 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 148 156 - T 28-03-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 A6A12_RS02430 58a2d93cca76c3797c7dcbe388c6370f 333 Gene3D G3DSA:3.40.190.10 131 333 3.4E-35 T 28-03-2018 A6A12_RS02430 58a2d93cca76c3797c7dcbe388c6370f 333 SUPERFAMILY SSF53850 22 330 1.6E-71 T 28-03-2018 A6A12_RS02430 58a2d93cca76c3797c7dcbe388c6370f 333 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 18 330 1.1E-136 T 28-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 A6A12_RS02430 58a2d93cca76c3797c7dcbe388c6370f 333 Pfam PF13531 Bacterial extracellular solute-binding protein 47 283 4.4E-36 T 28-03-2018 A6A12_RS02430 58a2d93cca76c3797c7dcbe388c6370f 333 Gene3D G3DSA:3.40.190.10 22 130 2.2E-20 T 28-03-2018 A6A12_RS06795 a0fb0b78e413566d89a68195c523e2ef 406 Gene3D G3DSA:1.10.3430.10 12 384 1.1E-92 T 28-03-2018 A6A12_RS06795 a0fb0b78e413566d89a68195c523e2ef 406 ProSitePatterns PS01219 Ammonium transporters signature. 167 192 - T 28-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 A6A12_RS06795 a0fb0b78e413566d89a68195c523e2ef 406 SUPERFAMILY SSF111352 17 383 1.7E-95 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 A6A12_RS06795 a0fb0b78e413566d89a68195c523e2ef 406 Pfam PF00909 Ammonium Transporter Family 23 401 8.1E-89 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 A6A12_RS11085 688e4644f22ad6242216f392555af59d 376 SUPERFAMILY SSF53335 189 357 2.54E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS11085 688e4644f22ad6242216f392555af59d 376 Hamap MF_01859 Ribosomal RNA large subunit methyltransferase G [rlmG]. 2 376 48.896 T 28-03-2018 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS11085 688e4644f22ad6242216f392555af59d 376 Pfam PF05175 Methyltransferase small domain 200 373 1.5E-52 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 A6A12_RS11085 688e4644f22ad6242216f392555af59d 376 PIRSF PIRSF037565 1 376 1.5E-169 T 28-03-2018 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS11085 688e4644f22ad6242216f392555af59d 376 Gene3D G3DSA:3.40.50.150 185 376 8.2E-27 T 28-03-2018 A6A12_RS11085 688e4644f22ad6242216f392555af59d 376 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 303 309 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A6A12_RS04165 a79ed847477856c66fd5f78eaa7aaae5 563 SUPERFAMILY SSF51445 9 475 1.26E-161 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A6A12_RS04165 a79ed847477856c66fd5f78eaa7aaae5 563 SMART SM00642 18 419 2.3E-162 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A6A12_RS04165 a79ed847477856c66fd5f78eaa7aaae5 563 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 10 557 1.6E-264 T 28-03-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 A6A12_RS04165 a79ed847477856c66fd5f78eaa7aaae5 563 Gene3D G3DSA:3.20.20.470 1 108 1.0E-37 T 28-03-2018 A6A12_RS04165 a79ed847477856c66fd5f78eaa7aaae5 563 Gene3D G3DSA:3.20.20.470 173 345 1.1E-37 T 28-03-2018 A6A12_RS04165 a79ed847477856c66fd5f78eaa7aaae5 563 Gene3D G3DSA:3.20.20.80 346 473 1.4E-22 T 28-03-2018 A6A12_RS04165 a79ed847477856c66fd5f78eaa7aaae5 563 Gene3D G3DSA:3.90.400.10 109 172 1.8E-28 T 28-03-2018 A6A12_RS04165 a79ed847477856c66fd5f78eaa7aaae5 563 SUPERFAMILY SSF51011 480 559 1.17E-14 T 28-03-2018 A6A12_RS04165 a79ed847477856c66fd5f78eaa7aaae5 563 Gene3D G3DSA:2.60.40.1180 481 560 2.1E-16 T 28-03-2018 A6A12_RS04165 a79ed847477856c66fd5f78eaa7aaae5 563 Pfam PF00128 Alpha amylase, catalytic domain 33 376 1.9E-127 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 Pfam PF11852 Domain of unknown function (DUF3372) 1236 1398 5.0E-56 T 28-03-2018 IPR024561 Alpha-1,6-glucosidases, pullulanase-type, C-terminal A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 SUPERFAMILY SSF51011 1299 1411 3.93E-35 T 28-03-2018 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 SUPERFAMILY SSF81296 510 630 4.2E-22 T 28-03-2018 IPR014756 Immunoglobulin E-set A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 642 729 5.0E-14 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 Pfam PF00128 Alpha amylase, catalytic domain 1694 1870 4.5E-13 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 Pfam PF00128 Alpha amylase, catalytic domain 1570 1664 1.7E-25 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 Gene3D G3DSA:4.10.1080.10 174 310 2.1E-16 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 Gene3D G3DSA:4.10.1080.10 311 390 9.9E-14 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 Pfam PF03714 Bacterial pullanase-associated domain 406 508 7.0E-17 T 28-03-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 SUPERFAMILY SSF103647 224 319 1.7E-9 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 Gene3D G3DSA:2.60.40.1110 391 508 3.0E-22 T 28-03-2018 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 Gene3D G3DSA:3.20.20.80 745 1306 4.3E-86 T 28-03-2018 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 Gene3D G3DSA:2.60.40.10 1416 1524 4.4E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 SUPERFAMILY SSF81296 641 744 1.36E-21 T 28-03-2018 IPR014756 Immunoglobulin E-set A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 SUPERFAMILY SSF49452 397 506 5.56E-28 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 Gene3D G3DSA:3.20.20.80 1529 1931 1.5E-62 T 28-03-2018 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 SUPERFAMILY SSF51011 1933 2012 6.48E-7 T 28-03-2018 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 Gene3D G3DSA:2.60.40.1180 1307 1410 5.7E-36 T 28-03-2018 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 SUPERFAMILY SSF51445 1536 1933 3.09E-65 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 SUPERFAMILY SSF103647 300 394 2.75E-11 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 SUPERFAMILY SSF51445 742 1294 1.42E-126 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 TIGRFAM TIGR02103 pullul_strch: alpha-1,6-glucosidases, pullulanase-type 520 1400 0.0 T 28-03-2018 IPR011839 Alpha-1,6-glucosidases, pullulanase-type GO:0005975|GO:0051060 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 Gene3D G3DSA:2.60.40.1130 520 629 4.0E-21 T 28-03-2018 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 SMART SM00642 1544 1924 2.3E-30 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 Gene3D G3DSA:2.60.40.1180 1932 2013 1.2E-11 T 28-03-2018 A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 Gene3D G3DSA:2.60.40.10 634 743 1.4E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS07900 2d40e533f89ef0f3680791f350c501a3 2013 SUPERFAMILY SSF81296 1418 1464 1.73E-5 T 28-03-2018 IPR014756 Immunoglobulin E-set A6A12_RS06440 635c8cfe3c6f54995e4adce5cb1a2d0b 272 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 262 1.4E-65 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS06440 635c8cfe3c6f54995e4adce5cb1a2d0b 272 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 262 4.0E-63 T 28-03-2018 IPR000150 Cof family GO:0016787 A6A12_RS06440 635c8cfe3c6f54995e4adce5cb1a2d0b 272 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 28-03-2018 A6A12_RS06440 635c8cfe3c6f54995e4adce5cb1a2d0b 272 ProSitePatterns PS01229 Hypothetical cof family signature 2. 216 238 - T 28-03-2018 A6A12_RS06440 635c8cfe3c6f54995e4adce5cb1a2d0b 272 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 235 1.9E-26 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A6A12_RS06440 635c8cfe3c6f54995e4adce5cb1a2d0b 272 SUPERFAMILY SSF56784 1 267 1.94E-75 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS06440 635c8cfe3c6f54995e4adce5cb1a2d0b 272 Gene3D G3DSA:3.40.50.1000 1 272 1.4E-45 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS08140 d0256fd966cf76686272a3887f62f0bc 327 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 87 2.6E-25 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 A6A12_RS08140 d0256fd966cf76686272a3887f62f0bc 327 Gene3D G3DSA:3.30.930.10 7 327 4.4E-93 T 28-03-2018 A6A12_RS08140 d0256fd966cf76686272a3887f62f0bc 327 Pfam PF01409 tRNA synthetases class II core domain (F) 92 326 5.7E-106 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A6A12_RS08140 d0256fd966cf76686272a3887f62f0bc 327 SUPERFAMILY SSF46589 13 99 4.81E-22 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 A6A12_RS08140 d0256fd966cf76686272a3887f62f0bc 327 SUPERFAMILY SSF55681 92 327 8.17E-82 T 28-03-2018 A6A12_RS08140 d0256fd966cf76686272a3887f62f0bc 327 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 326 49.049 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 A6A12_RS08140 d0256fd966cf76686272a3887f62f0bc 327 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 38 327 7.9E-112 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A6A12_RS12955 4c1cadd78c1c8cb85da44b0b5e838de8 302 Pfam PF01545 Cation efflux family 15 206 1.2E-43 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A6A12_RS12955 4c1cadd78c1c8cb85da44b0b5e838de8 302 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 287 6.5E-72 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A6A12_RS12955 4c1cadd78c1c8cb85da44b0b5e838de8 302 SUPERFAMILY SSF160240 210 288 7.98E-25 T 28-03-2018 A6A12_RS12955 4c1cadd78c1c8cb85da44b0b5e838de8 302 Gene3D G3DSA:1.20.1510.10 8 206 1.2E-40 T 28-03-2018 A6A12_RS12955 4c1cadd78c1c8cb85da44b0b5e838de8 302 Gene3D G3DSA:3.30.70.1350 207 290 1.0E-23 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain A6A12_RS12955 4c1cadd78c1c8cb85da44b0b5e838de8 302 SUPERFAMILY SSF161111 8 207 7.32E-52 T 28-03-2018 A6A12_RS12955 4c1cadd78c1c8cb85da44b0b5e838de8 302 Pfam PF16916 Dimerisation domain of Zinc Transporter 210 287 3.5E-26 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain A6A12_RS01050 2402d5aa8eb205a8e0eb723c26c859da 419 Gene3D G3DSA:3.40.50.300 129 419 5.4E-58 T 28-03-2018 A6A12_RS01050 2402d5aa8eb205a8e0eb723c26c859da 419 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 2.0E-16 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A6A12_RS01050 2402d5aa8eb205a8e0eb723c26c859da 419 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 1.9E-219 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A6A12_RS01050 2402d5aa8eb205a8e0eb723c26c859da 419 SMART SM00357 52 118 4.0E-18 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 A6A12_RS01050 2402d5aa8eb205a8e0eb723c26c859da 419 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 6.8E-23 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A6A12_RS01050 2402d5aa8eb205a8e0eb723c26c859da 419 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 251.391 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 A6A12_RS01050 2402d5aa8eb205a8e0eb723c26c859da 419 SMART SM00959 5 47 2.0E-17 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A6A12_RS01050 2402d5aa8eb205a8e0eb723c26c859da 419 SMART SM00382 170 355 1.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS01050 2402d5aa8eb205a8e0eb723c26c859da 419 Gene3D G3DSA:1.10.720.10 1 43 3.9E-12 T 28-03-2018 A6A12_RS01050 2402d5aa8eb205a8e0eb723c26c859da 419 SUPERFAMILY SSF68912 1 46 8.24E-12 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 A6A12_RS01050 2402d5aa8eb205a8e0eb723c26c859da 419 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 3.8E-32 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 A6A12_RS01050 2402d5aa8eb205a8e0eb723c26c859da 419 Gene3D G3DSA:2.40.50.140 49 116 4.5E-31 T 28-03-2018 A6A12_RS01050 2402d5aa8eb205a8e0eb723c26c859da 419 SUPERFAMILY SSF50249 48 125 2.14E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS01050 2402d5aa8eb205a8e0eb723c26c859da 419 SUPERFAMILY SSF52540 90 371 2.84E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS10495 36850a0eead91493483d8d45ef4ab850 553 PRINTS PR01607 Apyrase family signature 487 506 1.4E-51 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS10495 36850a0eead91493483d8d45ef4ab850 553 PRINTS PR01607 Apyrase family signature 36 54 1.4E-51 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS10495 36850a0eead91493483d8d45ef4ab850 553 PRINTS PR01607 Apyrase family signature 242 265 1.4E-51 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS10495 36850a0eead91493483d8d45ef4ab850 553 PRINTS PR01607 Apyrase family signature 287 307 1.4E-51 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS10495 36850a0eead91493483d8d45ef4ab850 553 PRINTS PR01607 Apyrase family signature 420 443 1.4E-51 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS10495 36850a0eead91493483d8d45ef4ab850 553 PRINTS PR01607 Apyrase family signature 211 228 1.4E-51 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS10495 36850a0eead91493483d8d45ef4ab850 553 SUPERFAMILY SSF56300 32 364 2.4E-96 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A6A12_RS10495 36850a0eead91493483d8d45ef4ab850 553 Pfam PF02872 5'-nucleotidase, C-terminal domain 366 512 2.0E-33 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS10495 36850a0eead91493483d8d45ef4ab850 553 Gene3D G3DSA:3.90.780.10 366 552 4.2E-45 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS10495 36850a0eead91493483d8d45ef4ab850 553 Gene3D G3DSA:3.60.21.10 30 365 8.6E-84 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A6A12_RS10495 36850a0eead91493483d8d45ef4ab850 553 SUPERFAMILY SSF55816 366 543 9.42E-52 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS10495 36850a0eead91493483d8d45ef4ab850 553 ProSitePatterns PS00786 5'-nucleotidase signature 2. 113 124 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS10495 36850a0eead91493483d8d45ef4ab850 553 ProSitePatterns PS00785 5'-nucleotidase signature 1. 38 50 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS10495 36850a0eead91493483d8d45ef4ab850 553 Pfam PF00149 Calcineurin-like phosphoesterase 38 259 1.8E-21 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A6A12_RS10550 e52983b1e6d8384c8826c4d202666582 363 PIRSF PIRSF006641 1 363 2.7E-159 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A6A12_RS10550 e52983b1e6d8384c8826c4d202666582 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 2.9E-170 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A6A12_RS10550 e52983b1e6d8384c8826c4d202666582 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 45.637 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 A6A12_RS10550 e52983b1e6d8384c8826c4d202666582 363 Pfam PF01926 50S ribosome-binding GTPase 5 120 6.3E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS10550 e52983b1e6d8384c8826c4d202666582 363 SUPERFAMILY SSF52540 3 301 6.3E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS10550 e52983b1e6d8384c8826c4d202666582 363 Gene3D G3DSA:3.10.20.30 263 362 1.6E-46 T 28-03-2018 IPR012675 Beta-grasp domain A6A12_RS10550 e52983b1e6d8384c8826c4d202666582 363 SUPERFAMILY SSF81271 279 360 1.83E-37 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A6A12_RS10550 e52983b1e6d8384c8826c4d202666582 363 Gene3D G3DSA:3.40.50.300 1 80 4.8E-8 T 28-03-2018 A6A12_RS10550 e52983b1e6d8384c8826c4d202666582 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 2.9E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS10550 e52983b1e6d8384c8826c4d202666582 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 2.9E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS10550 e52983b1e6d8384c8826c4d202666582 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 2.9E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS10550 e52983b1e6d8384c8826c4d202666582 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.9E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS10550 e52983b1e6d8384c8826c4d202666582 363 Gene3D G3DSA:1.10.150.300 110 200 4.8E-26 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 A6A12_RS10550 e52983b1e6d8384c8826c4d202666582 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 1.6E-40 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 A6A12_RS02590 0f4c0dae182d0c6bc061f0d09ec521eb 202 Gene3D G3DSA:3.40.50.300 1 198 3.7E-41 T 28-03-2018 A6A12_RS02590 0f4c0dae182d0c6bc061f0d09ec521eb 202 Pfam PF01121 Dephospho-CoA kinase 3 180 1.4E-72 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A6A12_RS02590 0f4c0dae182d0c6bc061f0d09ec521eb 202 SUPERFAMILY SSF52540 1 193 1.29E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS02590 0f4c0dae182d0c6bc061f0d09ec521eb 202 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 188 6.1E-65 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A6A12_RS02590 0f4c0dae182d0c6bc061f0d09ec521eb 202 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 193 27.353 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 A6A12_RS03010 3a9566b0fb402c7176fb0dd70e677fb9 292 Pfam PF01136 Peptidase family U32 81 206 4.4E-13 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A6A12_RS13240 602740c85eaa1b6a7e12d4f0dc191663 146 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 143 4.2E-38 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A6A12_RS13240 602740c85eaa1b6a7e12d4f0dc191663 146 SUPERFAMILY SSF52788 3 146 1.44E-41 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A6A12_RS13240 602740c85eaa1b6a7e12d4f0dc191663 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 5 22 2.9E-26 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A6A12_RS13240 602740c85eaa1b6a7e12d4f0dc191663 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 45 61 2.9E-26 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A6A12_RS13240 602740c85eaa1b6a7e12d4f0dc191663 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 79 94 2.9E-26 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A6A12_RS13240 602740c85eaa1b6a7e12d4f0dc191663 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 101 114 2.9E-26 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A6A12_RS13240 602740c85eaa1b6a7e12d4f0dc191663 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 117 132 2.9E-26 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A6A12_RS13240 602740c85eaa1b6a7e12d4f0dc191663 146 SMART SM00226 3 145 6.0E-53 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A6A12_RS13240 602740c85eaa1b6a7e12d4f0dc191663 146 Gene3D G3DSA:3.40.50.2300 3 146 7.0E-42 T 28-03-2018 A6A12_RS12770 d63b04bb295628cfe22c6a8490dfcb5a 273 Pfam PF06426 Serine acetyltransferase, N-terminal 9 112 2.6E-38 T 28-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 A6A12_RS12770 d63b04bb295628cfe22c6a8490dfcb5a 273 SUPERFAMILY SSF51161 7 260 1.66E-63 T 28-03-2018 IPR011004 Trimeric LpxA-like A6A12_RS12770 d63b04bb295628cfe22c6a8490dfcb5a 273 Gene3D G3DSA:1.10.3130.10 1 130 9.7E-38 T 28-03-2018 A6A12_RS12770 d63b04bb295628cfe22c6a8490dfcb5a 273 PIRSF PIRSF000441 75 266 2.3E-56 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 A6A12_RS12770 d63b04bb295628cfe22c6a8490dfcb5a 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 193 226 3.6E-9 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS12770 d63b04bb295628cfe22c6a8490dfcb5a 273 Gene3D G3DSA:2.160.10.10 131 265 1.1E-28 T 28-03-2018 A6A12_RS12770 d63b04bb295628cfe22c6a8490dfcb5a 273 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 202 230 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A6A12_RS12770 d63b04bb295628cfe22c6a8490dfcb5a 273 SMART SM00971 9 113 3.1E-61 T 28-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 A6A12_RS12770 d63b04bb295628cfe22c6a8490dfcb5a 273 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 82 242 5.6E-74 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 A6A12_RS00105 4a4cc33194860a297ee248b701051b3e 548 Gene3D G3DSA:3.40.50.970 334 535 9.6E-42 T 28-03-2018 A6A12_RS00105 4a4cc33194860a297ee248b701051b3e 548 Gene3D G3DSA:3.40.50.970 1 185 3.3E-61 T 28-03-2018 A6A12_RS00105 4a4cc33194860a297ee248b701051b3e 548 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 189 322 2.2E-39 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A6A12_RS00105 4a4cc33194860a297ee248b701051b3e 548 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 375 523 1.8E-47 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A6A12_RS00105 4a4cc33194860a297ee248b701051b3e 548 SUPERFAMILY SSF52518 1 175 1.35E-59 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS00105 4a4cc33194860a297ee248b701051b3e 548 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 412 431 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A6A12_RS00105 4a4cc33194860a297ee248b701051b3e 548 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 1 546 2.5E-206 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A6A12_RS00105 4a4cc33194860a297ee248b701051b3e 548 SUPERFAMILY SSF52518 358 545 1.05E-64 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS00105 4a4cc33194860a297ee248b701051b3e 548 Gene3D G3DSA:3.40.50.1220 186 333 1.2E-43 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A6A12_RS00105 4a4cc33194860a297ee248b701051b3e 548 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 167 8.6E-54 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A6A12_RS00105 4a4cc33194860a297ee248b701051b3e 548 SUPERFAMILY SSF52467 183 341 1.64E-54 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 PIRSF PIRSF000350 1 469 4.5E-83 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 Gene3D G3DSA:3.40.50.720 167 336 5.1E-30 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 3.2E-68 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 3.2E-68 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 3.2E-68 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 3.2E-68 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 3.2E-68 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 3.2E-68 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 3.2E-68 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 3.2E-68 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 3.2E-68 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 455 2.7E-35 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 Gene3D G3DSA:3.30.390.30 337 462 6.9E-38 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 5.9E-41 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 5.9E-41 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 5.9E-41 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 5.9E-41 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 5.9E-41 T 28-03-2018 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 Gene3D G3DSA:3.50.50.60 1 166 8.4E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 SUPERFAMILY SSF55424 343 466 6.36E-39 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 8 460 2.0E-149 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 42 52 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 328 7.8E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS02660 8c88d04c9c036663e7116689e716c7e9 475 SUPERFAMILY SSF51905 1 322 9.88E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS05855 2d5ce06ea993064d61d98f3575a57fd4 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.8E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS05855 2d5ce06ea993064d61d98f3575a57fd4 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.3E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS05855 2d5ce06ea993064d61d98f3575a57fd4 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.3E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS05855 2d5ce06ea993064d61d98f3575a57fd4 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.3E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS05855 2d5ce06ea993064d61d98f3575a57fd4 296 SUPERFAMILY SSF46785 3 83 9.07E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05855 2d5ce06ea993064d61d98f3575a57fd4 296 Pfam PF03466 LysR substrate binding domain 89 288 8.3E-27 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS05855 2d5ce06ea993064d61d98f3575a57fd4 296 Gene3D G3DSA:3.40.190.10 179 262 2.1E-11 T 28-03-2018 A6A12_RS05855 2d5ce06ea993064d61d98f3575a57fd4 296 Gene3D G3DSA:1.10.10.10 2 91 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05855 2d5ce06ea993064d61d98f3575a57fd4 296 Gene3D G3DSA:3.40.190.10 92 178 2.7E-12 T 28-03-2018 A6A12_RS05855 2d5ce06ea993064d61d98f3575a57fd4 296 SUPERFAMILY SSF53850 90 290 2.76E-32 T 28-03-2018 A6A12_RS05065 5316e5f872111cf7800884af24d07eb2 401 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 191 398 2.8E-71 T 28-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 A6A12_RS05065 5316e5f872111cf7800884af24d07eb2 401 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 5 78 3.5E-23 T 28-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 A6A12_RS05065 5316e5f872111cf7800884af24d07eb2 401 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 2 397 1.3E-133 T 28-03-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 A6A12_RS05065 5316e5f872111cf7800884af24d07eb2 401 Pfam PF07670 Nucleoside recognition 89 184 5.2E-7 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A6A12_RS03385 4eccd9ecf78331c1860f340695ad292b 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 225 5.5E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS03385 4eccd9ecf78331c1860f340695ad292b 229 SUPERFAMILY SSF52172 3 184 4.38E-43 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS03385 4eccd9ecf78331c1860f340695ad292b 229 Gene3D G3DSA:1.10.10.10 123 229 8.3E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03385 4eccd9ecf78331c1860f340695ad292b 229 SMART SM00448 3 116 2.8E-45 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS03385 4eccd9ecf78331c1860f340695ad292b 229 SMART SM00862 150 225 8.4E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS03385 4eccd9ecf78331c1860f340695ad292b 229 Gene3D G3DSA:3.40.50.2300 1 122 3.5E-37 T 28-03-2018 A6A12_RS03385 4eccd9ecf78331c1860f340695ad292b 229 Pfam PF00072 Response regulator receiver domain 5 116 1.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS03385 4eccd9ecf78331c1860f340695ad292b 229 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 1 226 1.0E-112 T 28-03-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 A6A12_RS12395 5fabda08eec26d9e66ad3c5eb7ed00a2 118 PIRSF PIRSF002134 1 118 1.3E-40 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12395 5fabda08eec26d9e66ad3c5eb7ed00a2 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12395 5fabda08eec26d9e66ad3c5eb7ed00a2 118 Pfam PF00416 Ribosomal protein S13/S18 3 108 1.7E-31 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12395 5fabda08eec26d9e66ad3c5eb7ed00a2 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 25.457 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12395 5fabda08eec26d9e66ad3c5eb7ed00a2 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 1.0E-52 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12395 5fabda08eec26d9e66ad3c5eb7ed00a2 118 Gene3D G3DSA:1.10.8.50 1 66 6.5E-22 T 28-03-2018 A6A12_RS12395 5fabda08eec26d9e66ad3c5eb7ed00a2 118 SUPERFAMILY SSF46946 2 114 1.46E-44 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A6A12_RS12395 5fabda08eec26d9e66ad3c5eb7ed00a2 118 Gene3D G3DSA:4.10.910.10 85 118 1.4E-25 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12395 5fabda08eec26d9e66ad3c5eb7ed00a2 118 Gene3D G3DSA:4.10.910.10 67 84 1.3E-19 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS05420 dcf78c67be91f11c08c7b87bf7ac7454 196 SUPERFAMILY SSF52317 3 192 8.49E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS05420 dcf78c67be91f11c08c7b87bf7ac7454 196 Gene3D G3DSA:3.40.50.880 1 193 2.0E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS05420 dcf78c67be91f11c08c7b87bf7ac7454 196 PRINTS PR00097 Anthranilate synthase component II signature 4 18 4.2E-35 T 28-03-2018 A6A12_RS05420 dcf78c67be91f11c08c7b87bf7ac7454 196 PRINTS PR00097 Anthranilate synthase component II signature 124 136 4.2E-35 T 28-03-2018 A6A12_RS05420 dcf78c67be91f11c08c7b87bf7ac7454 196 PRINTS PR00097 Anthranilate synthase component II signature 52 61 4.2E-35 T 28-03-2018 A6A12_RS05420 dcf78c67be91f11c08c7b87bf7ac7454 196 PRINTS PR00097 Anthranilate synthase component II signature 79 90 4.2E-35 T 28-03-2018 A6A12_RS05420 dcf78c67be91f11c08c7b87bf7ac7454 196 PRINTS PR00097 Anthranilate synthase component II signature 166 179 4.2E-35 T 28-03-2018 A6A12_RS05420 dcf78c67be91f11c08c7b87bf7ac7454 196 PRINTS PR00097 Anthranilate synthase component II signature 104 112 4.2E-35 T 28-03-2018 A6A12_RS05420 dcf78c67be91f11c08c7b87bf7ac7454 196 Pfam PF00117 Glutamine amidotransferase class-I 6 186 2.6E-45 T 28-03-2018 IPR017926 Glutamine amidotransferase A6A12_RS05420 dcf78c67be91f11c08c7b87bf7ac7454 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 79 90 4.8E-14 T 28-03-2018 A6A12_RS05420 dcf78c67be91f11c08c7b87bf7ac7454 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 4.8E-14 T 28-03-2018 A6A12_RS05420 dcf78c67be91f11c08c7b87bf7ac7454 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 52 61 4.8E-14 T 28-03-2018 A6A12_RS05420 dcf78c67be91f11c08c7b87bf7ac7454 196 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 49 63 1.1E-5 T 28-03-2018 A6A12_RS05420 dcf78c67be91f11c08c7b87bf7ac7454 196 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 79 95 1.1E-5 T 28-03-2018 A6A12_RS05420 dcf78c67be91f11c08c7b87bf7ac7454 196 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 187 4.9E-53 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A6A12_RS11350 0edf8aac78fe387aa9ebec265c9c9c27 226 SUPERFAMILY SSF52141 5 221 2.18E-96 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A6A12_RS11350 0edf8aac78fe387aa9ebec265c9c9c27 226 Gene3D G3DSA:3.40.470.10 1 226 1.5E-104 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A6A12_RS11350 0edf8aac78fe387aa9ebec265c9c9c27 226 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 57 66 - T 28-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A6A12_RS11350 0edf8aac78fe387aa9ebec265c9c9c27 226 Pfam PF03167 Uracil DNA glycosylase superfamily 55 209 5.2E-25 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A6A12_RS11350 0edf8aac78fe387aa9ebec265c9c9c27 226 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 6 214 1.3E-86 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A6A12_RS11350 0edf8aac78fe387aa9ebec265c9c9c27 226 SMART SM00987 49 210 6.2E-41 T 28-03-2018 A6A12_RS11350 0edf8aac78fe387aa9ebec265c9c9c27 226 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 4 221 40.175 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A6A12_RS11350 0edf8aac78fe387aa9ebec265c9c9c27 226 SMART SM00986 49 210 6.2E-41 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A6A12_RS03400 bf3b07734a548055538a170fdfb33756 501 SUPERFAMILY SSF53067 137 308 3.88E-45 T 28-03-2018 A6A12_RS03400 bf3b07734a548055538a170fdfb33756 501 Gene3D G3DSA:3.30.420.40 2 124 4.8E-39 T 28-03-2018 A6A12_RS03400 bf3b07734a548055538a170fdfb33756 501 PIRSF PIRSF001267 2 501 4.9E-201 T 28-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 A6A12_RS03400 bf3b07734a548055538a170fdfb33756 501 Pfam PF02541 Ppx/GppA phosphatase family 25 307 3.3E-87 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 A6A12_RS03400 bf3b07734a548055538a170fdfb33756 501 Gene3D G3DSA:3.30.420.150 125 304 2.7E-36 T 28-03-2018 A6A12_RS03400 bf3b07734a548055538a170fdfb33756 501 SUPERFAMILY SSF109604 312 500 3.06E-46 T 28-03-2018 A6A12_RS03400 bf3b07734a548055538a170fdfb33756 501 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 12 305 2.1E-102 T 28-03-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 A6A12_RS03400 bf3b07734a548055538a170fdfb33756 501 SUPERFAMILY SSF53067 12 132 1.44E-36 T 28-03-2018 A6A12_RS02450 b68e16ba49ad2e7cde98a895751b65ec 163 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 11 155 1.0E-48 T 28-03-2018 IPR008136 CinA, C-terminal A6A12_RS02450 b68e16ba49ad2e7cde98a895751b65ec 163 Pfam PF02464 Competence-damaged protein 7 158 3.4E-56 T 28-03-2018 IPR008136 CinA, C-terminal A6A12_RS02450 b68e16ba49ad2e7cde98a895751b65ec 163 SUPERFAMILY SSF142433 5 159 6.93E-54 T 28-03-2018 IPR008136 CinA, C-terminal A6A12_RS02450 b68e16ba49ad2e7cde98a895751b65ec 163 Gene3D G3DSA:3.90.950.20 2 163 2.6E-56 T 28-03-2018 A6A12_RS04220 ee74e7c68026609b0b49becf6883214d 412 SUPERFAMILY SSF52413 306 411 9.68E-22 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A6A12_RS04220 ee74e7c68026609b0b49becf6883214d 412 SMART SM00984 316 411 2.4E-18 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A6A12_RS04220 ee74e7c68026609b0b49becf6883214d 412 PIRSF PIRSF000124 3 412 4.0E-81 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A6A12_RS04220 ee74e7c68026609b0b49becf6883214d 412 SUPERFAMILY SSF48179 206 299 1.7E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A6A12_RS04220 ee74e7c68026609b0b49becf6883214d 412 Gene3D G3DSA:1.20.5.170 206 229 1.8E-15 T 28-03-2018 A6A12_RS04220 ee74e7c68026609b0b49becf6883214d 412 PIRSF PIRSF500136 1 412 3.3E-146 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A6A12_RS04220 ee74e7c68026609b0b49becf6883214d 412 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 410 3.2E-121 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A6A12_RS04220 ee74e7c68026609b0b49becf6883214d 412 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 316 412 5.7E-19 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A6A12_RS04220 ee74e7c68026609b0b49becf6883214d 412 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 189 1.3E-59 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A6A12_RS04220 ee74e7c68026609b0b49becf6883214d 412 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 206 293 4.8E-27 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A6A12_RS04220 ee74e7c68026609b0b49becf6883214d 412 Gene3D G3DSA:3.40.50.720 2 205 1.6E-47 T 28-03-2018 A6A12_RS04220 ee74e7c68026609b0b49becf6883214d 412 SUPERFAMILY SSF51735 4 199 2.71E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS04220 ee74e7c68026609b0b49becf6883214d 412 Gene3D G3DSA:3.40.50.720 230 412 2.6E-54 T 28-03-2018 A6A12_RS10245 2163251cceb27559db152e06a9ed4981 136 TIGRFAM TIGR00208 fliS: flagellar protein FliS 4 122 1.3E-23 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 A6A12_RS10245 2163251cceb27559db152e06a9ed4981 136 SUPERFAMILY SSF101116 6 127 4.71E-39 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 A6A12_RS10245 2163251cceb27559db152e06a9ed4981 136 Gene3D G3DSA:1.20.120.340 2 126 8.5E-43 T 28-03-2018 A6A12_RS10245 2163251cceb27559db152e06a9ed4981 136 PIRSF PIRSF039090 1 133 1.0E-43 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 A6A12_RS10245 2163251cceb27559db152e06a9ed4981 136 Pfam PF02561 Flagellar protein FliS 6 122 6.2E-38 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 A6A12_RS08310 9219eeb2c565cde22d52e888a28411af 446 SMART SM00267 259 431 3.6E-49 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS08310 9219eeb2c565cde22d52e888a28411af 446 Gene3D G3DSA:3.30.70.270 253 431 2.6E-53 T 28-03-2018 A6A12_RS08310 9219eeb2c565cde22d52e888a28411af 446 Pfam PF00990 Diguanylate cyclase, GGDEF domain 271 423 4.1E-46 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS08310 9219eeb2c565cde22d52e888a28411af 446 SUPERFAMILY SSF55073 275 429 1.88E-45 T 28-03-2018 IPR029787 Nucleotide cyclase A6A12_RS08310 9219eeb2c565cde22d52e888a28411af 446 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 266 427 3.5E-45 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS11480 c3f5a4fb265e3286f7f48d71255fb701 269 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 128 264 2.3E-44 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A6A12_RS11480 c3f5a4fb265e3286f7f48d71255fb701 269 SUPERFAMILY SSF51735 236 268 1.33E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS11480 c3f5a4fb265e3286f7f48d71255fb701 269 SUPERFAMILY SSF51735 1 126 1.33E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS11480 c3f5a4fb265e3286f7f48d71255fb701 269 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 265 35.5 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A6A12_RS11480 c3f5a4fb265e3286f7f48d71255fb701 269 SUPERFAMILY SSF55347 127 236 7.19E-38 T 28-03-2018 A6A12_RS11480 c3f5a4fb265e3286f7f48d71255fb701 269 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 2 125 1.1E-39 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A6A12_RS11480 c3f5a4fb265e3286f7f48d71255fb701 269 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 265 2.8E-100 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A6A12_RS11480 c3f5a4fb265e3286f7f48d71255fb701 269 Gene3D G3DSA:3.40.50.720 1 140 7.3E-27 T 28-03-2018 A6A12_RS11480 c3f5a4fb265e3286f7f48d71255fb701 269 Gene3D G3DSA:3.30.360.10 141 234 2.4E-36 T 28-03-2018 A6A12_RS11480 c3f5a4fb265e3286f7f48d71255fb701 269 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 150 167 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A6A12_RS11480 c3f5a4fb265e3286f7f48d71255fb701 269 PIRSF PIRSF000161 1 268 8.1E-88 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A6A12_RS05190 9f583fbd9d0b74ca90b8a769ceaff994 208 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 16 206 44.537 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A6A12_RS05190 9f583fbd9d0b74ca90b8a769ceaff994 208 PRINTS PR00127 Clp protease catalytic subunit P signature 32 47 2.3E-54 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A6A12_RS05190 9f583fbd9d0b74ca90b8a769ceaff994 208 PRINTS PR00127 Clp protease catalytic subunit P signature 181 200 2.3E-54 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A6A12_RS05190 9f583fbd9d0b74ca90b8a769ceaff994 208 PRINTS PR00127 Clp protease catalytic subunit P signature 103 120 2.3E-54 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A6A12_RS05190 9f583fbd9d0b74ca90b8a769ceaff994 208 PRINTS PR00127 Clp protease catalytic subunit P signature 72 92 2.3E-54 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A6A12_RS05190 9f583fbd9d0b74ca90b8a769ceaff994 208 PRINTS PR00127 Clp protease catalytic subunit P signature 124 143 2.3E-54 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A6A12_RS05190 9f583fbd9d0b74ca90b8a769ceaff994 208 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 15 205 2.1E-107 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A6A12_RS05190 9f583fbd9d0b74ca90b8a769ceaff994 208 SUPERFAMILY SSF52096 23 206 1.44E-75 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS05190 9f583fbd9d0b74ca90b8a769ceaff994 208 Pfam PF00574 Clp protease 25 205 5.4E-90 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A6A12_RS05190 9f583fbd9d0b74ca90b8a769ceaff994 208 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 125 138 - T 28-03-2018 IPR033135 ClpP, histidine active site A6A12_RS05190 9f583fbd9d0b74ca90b8a769ceaff994 208 Gene3D G3DSA:3.90.226.10 15 207 1.1E-48 T 28-03-2018 A6A12_RS05190 9f583fbd9d0b74ca90b8a769ceaff994 208 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 103 114 - T 28-03-2018 IPR018215 ClpP, Ser active site A6A12_RS12750 68f5d769aff17c6248487791849c42be 333 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 332 3.8E-119 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A6A12_RS12750 68f5d769aff17c6248487791849c42be 333 SUPERFAMILY SSF55347 154 307 2.88E-48 T 28-03-2018 A6A12_RS12750 68f5d769aff17c6248487791849c42be 333 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 163 310 9.9E-11 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A6A12_RS12750 68f5d769aff17c6248487791849c42be 333 Gene3D G3DSA:3.30.360.10 164 307 2.5E-48 T 28-03-2018 A6A12_RS12750 68f5d769aff17c6248487791849c42be 333 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 333 37.211 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A6A12_RS12750 68f5d769aff17c6248487791849c42be 333 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 149 165 - T 28-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A6A12_RS12750 68f5d769aff17c6248487791849c42be 333 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 145 4.7E-33 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A6A12_RS12750 68f5d769aff17c6248487791849c42be 333 SUPERFAMILY SSF51735 1 173 1.04E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS12750 68f5d769aff17c6248487791849c42be 333 Gene3D G3DSA:3.40.50.720 1 163 1.6E-38 T 28-03-2018 A6A12_RS12750 68f5d769aff17c6248487791849c42be 333 SMART SM00859 3 146 2.2E-48 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A6A12_RS14435 7cdf58f742837e8151a58b40817b8f2a 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS14435 7cdf58f742837e8151a58b40817b8f2a 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 44 2.1E-25 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS14435 7cdf58f742837e8151a58b40817b8f2a 45 Pfam PF00468 Ribosomal protein L34 3 44 2.4E-23 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS14435 7cdf58f742837e8151a58b40817b8f2a 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 16.235 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS14435 7cdf58f742837e8151a58b40817b8f2a 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 40 4.0E-14 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS11910 a199e53d2bc28248c1da92b9ff7c3685 579 Gene3D G3DSA:3.40.50.1220 207 361 1.4E-52 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A6A12_RS11910 a199e53d2bc28248c1da92b9ff7c3685 579 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 438 457 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 A6A12_RS11910 a199e53d2bc28248c1da92b9ff7c3685 579 Gene3D G3DSA:3.40.50.970 3 206 8.3E-65 T 28-03-2018 A6A12_RS11910 a199e53d2bc28248c1da92b9ff7c3685 579 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 203 337 6.4E-47 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A6A12_RS11910 a199e53d2bc28248c1da92b9ff7c3685 579 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 401 550 2.2E-49 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A6A12_RS11910 a199e53d2bc28248c1da92b9ff7c3685 579 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 10 574 6.8E-274 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A6A12_RS11910 a199e53d2bc28248c1da92b9ff7c3685 579 SUPERFAMILY SSF52518 378 572 4.76E-67 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS11910 a199e53d2bc28248c1da92b9ff7c3685 579 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 11 178 1.8E-58 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A6A12_RS11910 a199e53d2bc28248c1da92b9ff7c3685 579 SUPERFAMILY SSF52518 7 188 7.15E-65 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS11910 a199e53d2bc28248c1da92b9ff7c3685 579 Gene3D G3DSA:3.40.50.970 362 570 1.4E-49 T 28-03-2018 A6A12_RS11910 a199e53d2bc28248c1da92b9ff7c3685 579 SUPERFAMILY SSF52467 196 369 2.46E-63 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A6A12_RS03165 ff7abfd407aec34aa7d2c352131fb659 381 Pfam PF02690 Na+/Pi-cotransporter 217 322 7.5E-19 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 A6A12_RS03165 ff7abfd407aec34aa7d2c352131fb659 381 Pfam PF02690 Na+/Pi-cotransporter 29 149 2.7E-19 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 A6A12_RS10325 3cf958b846aeed6d5ec659cae50a17de 339 Pfam PF06804 NlpB/DapX lipoprotein 36 335 4.7E-104 T 28-03-2018 IPR010653 NlpB/DapX lipoprotein A6A12_RS10325 3cf958b846aeed6d5ec659cae50a17de 339 Hamap MF_00924 Outer membrane protein assembly factor BamC [bamC]. 4 337 34.091 T 28-03-2018 IPR014524 Outer membrane protein assembly factor BamC A6A12_RS10325 3cf958b846aeed6d5ec659cae50a17de 339 PIRSF PIRSF026343 4 339 1.5E-126 T 28-03-2018 IPR014524 Outer membrane protein assembly factor BamC A6A12_RS07500 83427e0c2b6d04d0cd52cb020eedf224 369 Gene3D G3DSA:2.120.10.30 36 357 9.6E-9 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like A6A12_RS07500 83427e0c2b6d04d0cd52cb020eedf224 369 PIRSF PIRSF028101 4 363 3.2E-153 T 28-03-2018 IPR008311 Uncharacterised conserved protein UCP028101 A6A12_RS07500 83427e0c2b6d04d0cd52cb020eedf224 369 Pfam PF07433 Protein of unknown function (DUF1513) 69 361 7.2E-111 T 28-03-2018 IPR008311 Uncharacterised conserved protein UCP028101 A6A12_RS07500 83427e0c2b6d04d0cd52cb020eedf224 369 SUPERFAMILY SSF75011 54 187 5.75E-13 T 28-03-2018 A6A12_RS10815 795d1fbf88d90f7c770627bc28723d64 114 ProSitePatterns PS00496 P-II protein uridylation site. 48 53 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 A6A12_RS10815 795d1fbf88d90f7c770627bc28723d64 114 Pfam PF00543 Nitrogen regulatory protein P-II 6 107 2.4E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A6A12_RS10815 795d1fbf88d90f7c770627bc28723d64 114 Gene3D G3DSA:3.30.70.120 1 110 1.9E-50 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A6A12_RS10815 795d1fbf88d90f7c770627bc28723d64 114 ProSitePatterns PS00638 P-II protein C-terminal region signature. 85 98 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 A6A12_RS10815 795d1fbf88d90f7c770627bc28723d64 114 SUPERFAMILY SSF54913 3 114 6.99E-47 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A6A12_RS10815 795d1fbf88d90f7c770627bc28723d64 114 PRINTS PR00340 P-II protein signature 25 43 2.7E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A6A12_RS10815 795d1fbf88d90f7c770627bc28723d64 114 PRINTS PR00340 P-II protein signature 54 77 2.7E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A6A12_RS10815 795d1fbf88d90f7c770627bc28723d64 114 PRINTS PR00340 P-II protein signature 85 105 2.7E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A6A12_RS10815 795d1fbf88d90f7c770627bc28723d64 114 PRINTS PR00340 P-II protein signature 4 19 2.7E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A6A12_RS10815 795d1fbf88d90f7c770627bc28723d64 114 PIRSF PIRSF039144 3 114 2.1E-58 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A6A12_RS10815 795d1fbf88d90f7c770627bc28723d64 114 SMART SM00938 6 107 4.8E-69 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A6A12_RS02090 e2b94460a457431b8e61bd0a5f9770df 94 Pfam PF05488 PAAR motif 19 86 6.5E-19 T 28-03-2018 IPR008727 PAAR motif A6A12_RS08525 fc48a0d09b6d2b7bb46628cd48b0ccb0 96 Gene3D G3DSA:3.40.50.10400 1 96 4.3E-23 T 28-03-2018 IPR027269 Hypothetical PA1492 domain A6A12_RS08525 fc48a0d09b6d2b7bb46628cd48b0ccb0 96 Pfam PF14359 Domain of unknown function (DUF4406) 6 95 2.9E-33 T 28-03-2018 IPR025518 Protein of unknown function DUF4406 A6A12_RS08525 fc48a0d09b6d2b7bb46628cd48b0ccb0 96 SUPERFAMILY SSF52309 4 95 4.88E-26 T 28-03-2018 A6A12_RS09675 19c731a245f7d67d19868990989e655e 414 SUPERFAMILY SSF53901 215 413 8.49E-67 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS09675 19c731a245f7d67d19868990989e655e 414 Gene3D G3DSA:3.40.47.10 261 414 1.8E-49 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS09675 19c731a245f7d67d19868990989e655e 414 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 247 4.2E-64 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A6A12_RS09675 19c731a245f7d67d19868990989e655e 414 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 412 2.6E-190 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A6A12_RS09675 19c731a245f7d67d19868990989e655e 414 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site A6A12_RS09675 19c731a245f7d67d19868990989e655e 414 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 370 1.1E-36 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A6A12_RS09675 19c731a245f7d67d19868990989e655e 414 Gene3D G3DSA:3.40.47.10 6 260 2.5E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS09675 19c731a245f7d67d19868990989e655e 414 SUPERFAMILY SSF53901 3 252 9.6E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS09675 19c731a245f7d67d19868990989e655e 414 SMART SM00825 Beta-ketoacyl synthase 6 414 2.3E-15 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A6A12_RS09675 19c731a245f7d67d19868990989e655e 414 PIRSF PIRSF000447 1 414 2.4E-202 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 A6A12_RS11685 8f3e373b03ba8c487279369405271160 209 ProSitePatterns PS00893 Nudix box signature. 96 117 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A6A12_RS11685 8f3e373b03ba8c487279369405271160 209 SUPERFAMILY SSF55811 11 203 4.47E-47 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A6A12_RS11685 8f3e373b03ba8c487279369405271160 209 Gene3D G3DSA:3.90.79.10 1 208 6.6E-44 T 28-03-2018 A6A12_RS11685 8f3e373b03ba8c487279369405271160 209 Pfam PF00293 NUDIX domain 58 178 3.6E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A6A12_RS11685 8f3e373b03ba8c487279369405271160 209 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 14 198 3.6E-61 T 28-03-2018 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 A6A12_RS13030 be4cad618458c9900916a08e12a77f5f 154 SUPERFAMILY SSF54893 2 100 6.15E-36 T 28-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A6A12_RS13030 be4cad618458c9900916a08e12a77f5f 154 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 7 97 1.5E-30 T 28-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A6A12_RS13030 be4cad618458c9900916a08e12a77f5f 154 SUPERFAMILY SSF57825 101 151 2.88E-15 T 28-03-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal A6A12_RS13030 be4cad618458c9900916a08e12a77f5f 154 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 5 150 9.3E-60 T 28-03-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A6A12_RS13030 be4cad618458c9900916a08e12a77f5f 154 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 4 152 32.964 T 28-03-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A6A12_RS13030 be4cad618458c9900916a08e12a77f5f 154 Gene3D G3DSA:3.30.70.140 5 97 5.8E-34 T 28-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A6A12_RS13030 be4cad618458c9900916a08e12a77f5f 154 Gene3D G3DSA:2.30.30.20 100 147 1.2E-17 T 28-03-2018 A6A12_RS13030 be4cad618458c9900916a08e12a77f5f 154 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 102 149 6.4E-18 T 28-03-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal A6A12_RS13030 be4cad618458c9900916a08e12a77f5f 154 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 9 99 1.0E-36 T 28-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A6A12_RS06695 4f2554b771cd2c2f099c714d51bef31d 477 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 207 262 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A6A12_RS06695 4f2554b771cd2c2f099c714d51bef31d 477 Gene3D G3DSA:1.20.210.10 5 473 8.3E-95 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A6A12_RS06695 4f2554b771cd2c2f099c714d51bef31d 477 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 17 447 4.4E-114 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A6A12_RS06695 4f2554b771cd2c2f099c714d51bef31d 477 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 11 466 3.4E-228 T 28-03-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 A6A12_RS06695 4f2554b771cd2c2f099c714d51bef31d 477 SUPERFAMILY SSF81442 13 467 3.79E-121 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 A6A12_RS01295 0127b04409a8da47586631e27efca7ca 315 SUPERFAMILY SSF52540 10 153 1.26E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01295 0127b04409a8da47586631e27efca7ca 315 Gene3D G3DSA:3.40.50.300 2 155 2.4E-50 T 28-03-2018 A6A12_RS01295 0127b04409a8da47586631e27efca7ca 315 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 9 295 6.6E-116 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A6A12_RS01295 0127b04409a8da47586631e27efca7ca 315 Gene3D G3DSA:1.10.287.890 203 285 3.9E-25 T 28-03-2018 A6A12_RS01295 0127b04409a8da47586631e27efca7ca 315 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 8 301 29.775 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A6A12_RS01295 0127b04409a8da47586631e27efca7ca 315 Pfam PF01715 IPP transferase 42 287 5.0E-85 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 A6A12_RS01355 e4a1a21ffc662e475163845d1d114234 91 TIGRFAM TIGR03011 sulf_tusB_dsrH: sulfur relay protein TusB/DsrH 9 91 2.1E-17 T 28-03-2018 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 A6A12_RS01355 e4a1a21ffc662e475163845d1d114234 91 SUPERFAMILY SSF75169 1 91 4.0E-17 T 28-03-2018 IPR027396 DsrEFH-like A6A12_RS01355 e4a1a21ffc662e475163845d1d114234 91 Gene3D G3DSA:3.40.1260.10 1 89 2.3E-13 T 28-03-2018 A6A12_RS01355 e4a1a21ffc662e475163845d1d114234 91 Pfam PF04077 DsrH like protein 9 87 6.6E-17 T 28-03-2018 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 A6A12_RS05500 8373d1d08955d0b3a3fd5a9bcceb64d9 412 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 6 407 1.9E-163 T 28-03-2018 IPR011340 Cysteine desulfurase-related A6A12_RS05500 8373d1d08955d0b3a3fd5a9bcceb64d9 412 Gene3D G3DSA:3.90.1150.10 273 412 1.7E-30 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS05500 8373d1d08955d0b3a3fd5a9bcceb64d9 412 SUPERFAMILY SSF53383 8 409 3.23E-94 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS05500 8373d1d08955d0b3a3fd5a9bcceb64d9 412 Pfam PF00266 Aminotransferase class-V 29 404 1.9E-71 T 28-03-2018 IPR000192 Aminotransferase class V domain A6A12_RS05500 8373d1d08955d0b3a3fd5a9bcceb64d9 412 Gene3D G3DSA:3.40.640.10 36 272 1.0E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 SUPERFAMILY SSF52540 141 385 5.43E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 Gene3D G3DSA:3.40.50.300 138 314 9.4E-28 T 28-03-2018 A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 Gene3D G3DSA:1.10.10.60 387 467 1.2E-23 T 28-03-2018 A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 6 466 2.0E-242 T 28-03-2018 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 Pfam PF00158 Sigma-54 interaction domain 142 309 3.1E-71 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 Pfam PF02954 Bacterial regulatory protein, Fis family 426 466 2.4E-15 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 Gene3D G3DSA:3.40.50.2300 3 137 3.5E-35 T 28-03-2018 A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 SMART SM00448 4 115 5.5E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 SMART SM00382 162 313 9.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 SUPERFAMILY SSF52172 2 187 7.68E-43 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 Pfam PF00072 Response regulator receiver domain 6 115 2.0E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 SUPERFAMILY SSF46689 383 466 1.54E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 Gene3D G3DSA:1.10.8.60 315 386 1.5E-20 T 28-03-2018 A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 432 449 6.3E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS00795 eb381b6206eb39e4759ad5e9376b63de 467 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 449 467 6.3E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 SMART SM00532 4 449 4.1E-277 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 596 668 6.1E-11 T 28-03-2018 IPR001357 BRCT domain A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 332 347 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 Gene3D G3DSA:1.10.150.20 433 506 2.3E-25 T 28-03-2018 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 PIRSF PIRSF001604 1 671 5.3E-255 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 323 398 5.3E-35 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 SMART SM00278 447 466 27.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 SMART SM00278 545 564 340.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 SMART SM00278 481 500 0.52 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 409 435 6.4E-10 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 12 665 9.3E-263 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 Gene3D G3DSA:2.40.50.140 318 391 2.4E-34 T 28-03-2018 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 Gene3D G3DSA:1.10.150.20 507 572 7.4E-25 T 28-03-2018 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 Gene3D G3DSA:1.10.287.610 2 68 2.5E-24 T 28-03-2018 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 Pfam PF12826 Helix-hairpin-helix motif 511 574 1.7E-23 T 28-03-2018 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 Pfam PF14520 Helix-hairpin-helix domain 447 501 3.8E-6 T 28-03-2018 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 Gene3D G3DSA:3.40.50.10190 573 671 1.7E-21 T 28-03-2018 IPR001357 BRCT domain A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 SUPERFAMILY SSF50249 319 399 3.26E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 5 319 1.3E-134 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 116 145 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 Hamap MF_01588 DNA ligase [ligA]. 3 669 52.982 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 Gene3D G3DSA:3.30.470.30 120 253 1.3E-52 T 28-03-2018 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 SUPERFAMILY SSF56091 3 317 7.68E-125 T 28-03-2018 A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 SMART SM00292 595 671 1.4E-8 T 28-03-2018 IPR001357 BRCT domain A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 SUPERFAMILY SSF47781 404 584 6.35E-61 T 28-03-2018 IPR010994 RuvA domain 2-like A6A12_RS04460 b9b38324be84dfbc062c56431413fa0d 671 SUPERFAMILY SSF52113 594 670 4.09E-17 T 28-03-2018 IPR001357 BRCT domain A6A12_RS02685 8a1b5d154cc97b0d6ce4b74eab67a298 306 SUPERFAMILY SSF52540 3 232 1.41E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS02685 8a1b5d154cc97b0d6ce4b74eab67a298 306 Pfam PF00005 ABC transporter 20 164 7.3E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS02685 8a1b5d154cc97b0d6ce4b74eab67a298 306 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS02685 8a1b5d154cc97b0d6ce4b74eab67a298 306 Gene3D G3DSA:3.40.50.300 1 292 1.1E-65 T 28-03-2018 A6A12_RS02685 8a1b5d154cc97b0d6ce4b74eab67a298 306 SMART SM00382 29 212 7.0E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS07995 ff70f23972894b7e4a83d1a4f9575379 188 Pfam PF07209 Protein of unknown function (DUF1415) 10 177 6.8E-65 T 28-03-2018 IPR009858 Protein of unknown function DUF1415 A6A12_RS08070 e44b6711bb17ee7d1817b2e03e8317a3 652 SUPERFAMILY SSF58104 342 651 1.7E-75 T 28-03-2018 A6A12_RS08070 e44b6711bb17ee7d1817b2e03e8317a3 652 SMART SM00304 320 374 2.9E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS08070 e44b6711bb17ee7d1817b2e03e8317a3 652 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 434 617 1.5E-42 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS08070 e44b6711bb17ee7d1817b2e03e8317a3 652 Gene3D G3DSA:1.10.287.1060 344 426 0.0059 T 28-03-2018 A6A12_RS08070 e44b6711bb17ee7d1817b2e03e8317a3 652 Gene3D G3DSA:1.10.287.950 427 652 4.9E-51 T 28-03-2018 A6A12_RS08070 e44b6711bb17ee7d1817b2e03e8317a3 652 Gene3D G3DSA:3.30.450.20 185 298 2.9E-18 T 28-03-2018 A6A12_RS08070 e44b6711bb17ee7d1817b2e03e8317a3 652 SMART SM00283 389 650 1.3E-75 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS08070 e44b6711bb17ee7d1817b2e03e8317a3 652 Pfam PF02743 Cache domain 35 282 4.9E-29 T 28-03-2018 IPR033479 Double Cache domain 1 A6A12_RS08070 e44b6711bb17ee7d1817b2e03e8317a3 652 Gene3D G3DSA:3.30.450.20 25 184 7.0E-14 T 28-03-2018 A6A12_RS02530 34c1e5a9a016d94b912b38eff37460d3 951 Gene3D G3DSA:3.30.830.10 32 273 6.6E-59 T 28-03-2018 A6A12_RS02530 34c1e5a9a016d94b912b38eff37460d3 951 SUPERFAMILY SSF63411 49 258 4.4E-56 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A6A12_RS02530 34c1e5a9a016d94b912b38eff37460d3 951 Pfam PF00675 Insulinase (Peptidase family M16) 537 645 3.6E-10 T 28-03-2018 IPR011765 Peptidase M16, N-terminal A6A12_RS02530 34c1e5a9a016d94b912b38eff37460d3 951 Pfam PF00675 Insulinase (Peptidase family M16) 62 183 6.6E-19 T 28-03-2018 IPR011765 Peptidase M16, N-terminal A6A12_RS02530 34c1e5a9a016d94b912b38eff37460d3 951 SUPERFAMILY SSF63411 281 468 3.67E-29 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A6A12_RS02530 34c1e5a9a016d94b912b38eff37460d3 951 Pfam PF05193 Peptidase M16 inactive domain 686 857 1.9E-21 T 28-03-2018 IPR007863 Peptidase M16, C-terminal A6A12_RS02530 34c1e5a9a016d94b912b38eff37460d3 951 Pfam PF05193 Peptidase M16 inactive domain 219 392 1.2E-26 T 28-03-2018 IPR007863 Peptidase M16, C-terminal A6A12_RS02530 34c1e5a9a016d94b912b38eff37460d3 951 Gene3D G3DSA:3.30.830.10 485 724 9.1E-43 T 28-03-2018 A6A12_RS02530 34c1e5a9a016d94b912b38eff37460d3 951 SUPERFAMILY SSF63411 737 942 5.33E-39 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A6A12_RS02530 34c1e5a9a016d94b912b38eff37460d3 951 Gene3D G3DSA:3.30.830.10 275 476 6.8E-29 T 28-03-2018 A6A12_RS02530 34c1e5a9a016d94b912b38eff37460d3 951 Gene3D G3DSA:3.30.830.10 741 941 1.1E-28 T 28-03-2018 A6A12_RS02530 34c1e5a9a016d94b912b38eff37460d3 951 SUPERFAMILY SSF63411 519 721 1.31E-44 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A6A12_RS13405 35a98f53498420243f7b0081de3bea03 295 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 3 291 1.5E-104 T 28-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 A6A12_RS13405 35a98f53498420243f7b0081de3bea03 295 SUPERFAMILY SSF51735 2 292 7.1E-104 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS13405 35a98f53498420243f7b0081de3bea03 295 Gene3D G3DSA:3.90.25.10 175 200 1.2E-8 T 28-03-2018 A6A12_RS13405 35a98f53498420243f7b0081de3bea03 295 Pfam PF04321 RmlD substrate binding domain 2 291 4.6E-110 T 28-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 A6A12_RS13405 35a98f53498420243f7b0081de3bea03 295 Gene3D G3DSA:3.40.50.720 1 174 3.0E-23 T 28-03-2018 A6A12_RS13405 35a98f53498420243f7b0081de3bea03 295 Gene3D G3DSA:3.90.25.10 201 280 1.7E-24 T 28-03-2018 A6A12_RS07210 db932b07315cb7b4a260442157bf8397 934 SUPERFAMILY SSF53067 403 456 1.15E-18 T 28-03-2018 A6A12_RS07210 db932b07315cb7b4a260442157bf8397 934 SUPERFAMILY SSF53067 223 370 1.15E-18 T 28-03-2018 A6A12_RS07210 db932b07315cb7b4a260442157bf8397 934 Gene3D G3DSA:3.30.420.40 6 230 1.7E-31 T 28-03-2018 A6A12_RS07210 db932b07315cb7b4a260442157bf8397 934 Pfam PF00012 Hsp70 protein 133 316 3.7E-14 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS07210 db932b07315cb7b4a260442157bf8397 934 Pfam PF12531 DNA-K related protein 684 931 8.0E-101 T 28-03-2018 IPR021030 Protein of unknown function DUF3731 A6A12_RS07210 db932b07315cb7b4a260442157bf8397 934 PRINTS PR00301 70kDa heat shock protein signature 232 242 2.0E-7 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS07210 db932b07315cb7b4a260442157bf8397 934 PRINTS PR00301 70kDa heat shock protein signature 165 185 2.0E-7 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS07210 db932b07315cb7b4a260442157bf8397 934 PRINTS PR00301 70kDa heat shock protein signature 6 19 2.0E-7 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS07210 db932b07315cb7b4a260442157bf8397 934 Gene3D G3DSA:3.30.420.40 231 431 7.7E-15 T 28-03-2018 A6A12_RS07210 db932b07315cb7b4a260442157bf8397 934 SUPERFAMILY SSF53067 6 208 7.77E-30 T 28-03-2018 A6A12_RS10660 08ace45f9ef48fe5723ba80db09e8dd7 308 Pfam PF01584 CheW-like domain 21 155 7.6E-34 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS10660 08ace45f9ef48fe5723ba80db09e8dd7 308 Gene3D G3DSA:3.40.50.2300 176 308 4.6E-26 T 28-03-2018 A6A12_RS10660 08ace45f9ef48fe5723ba80db09e8dd7 308 PIRSF PIRSF002867 1 308 3.7E-102 T 28-03-2018 IPR024181 Chemotaxis response regulator CheV A6A12_RS10660 08ace45f9ef48fe5723ba80db09e8dd7 308 SMART SM00260 17 153 1.6E-25 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS10660 08ace45f9ef48fe5723ba80db09e8dd7 308 SMART SM00448 182 302 2.9E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS10660 08ace45f9ef48fe5723ba80db09e8dd7 308 Gene3D G3DSA:2.30.30.40 105 147 4.8E-11 T 28-03-2018 A6A12_RS10660 08ace45f9ef48fe5723ba80db09e8dd7 308 Gene3D G3DSA:2.40.50.180 39 104 9.4E-13 T 28-03-2018 A6A12_RS10660 08ace45f9ef48fe5723ba80db09e8dd7 308 SUPERFAMILY SSF50341 16 156 3.92E-35 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS10660 08ace45f9ef48fe5723ba80db09e8dd7 308 SUPERFAMILY SSF52172 183 306 2.13E-26 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS10660 08ace45f9ef48fe5723ba80db09e8dd7 308 Pfam PF00072 Response regulator receiver domain 184 302 1.1E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS07010 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13007 Transposase C of IS166 homeodomain 42 111 2.7E-13 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain A6A12_RS07010 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13817 IS66 C-terminal element 473 509 3.3E-9 T 28-03-2018 A6A12_RS07010 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13005 zinc-finger binding domain of transposase IS66 119 163 1.7E-16 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 A6A12_RS07010 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF03050 Transposase IS66 family 183 466 1.5E-101 T 28-03-2018 IPR004291 Transposase, IS66 A6A12_RS13845 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13007 Transposase C of IS166 homeodomain 42 111 2.7E-13 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain A6A12_RS13845 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13817 IS66 C-terminal element 473 509 3.3E-9 T 28-03-2018 A6A12_RS13845 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13005 zinc-finger binding domain of transposase IS66 119 163 1.7E-16 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 A6A12_RS13845 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF03050 Transposase IS66 family 183 466 1.5E-101 T 28-03-2018 IPR004291 Transposase, IS66 A6A12_RS13670 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13007 Transposase C of IS166 homeodomain 42 111 2.7E-13 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain A6A12_RS13670 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13817 IS66 C-terminal element 473 509 3.3E-9 T 28-03-2018 A6A12_RS13670 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13005 zinc-finger binding domain of transposase IS66 119 163 1.7E-16 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 A6A12_RS13670 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF03050 Transposase IS66 family 183 466 1.5E-101 T 28-03-2018 IPR004291 Transposase, IS66 A6A12_RS00185 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13007 Transposase C of IS166 homeodomain 42 111 2.7E-13 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain A6A12_RS00185 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13817 IS66 C-terminal element 473 509 3.3E-9 T 28-03-2018 A6A12_RS00185 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13005 zinc-finger binding domain of transposase IS66 119 163 1.7E-16 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 A6A12_RS00185 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF03050 Transposase IS66 family 183 466 1.5E-101 T 28-03-2018 IPR004291 Transposase, IS66 A6A12_RS07695 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13007 Transposase C of IS166 homeodomain 42 111 2.7E-13 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain A6A12_RS07695 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13817 IS66 C-terminal element 473 509 3.3E-9 T 28-03-2018 A6A12_RS07695 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13005 zinc-finger binding domain of transposase IS66 119 163 1.7E-16 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 A6A12_RS07695 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF03050 Transposase IS66 family 183 466 1.5E-101 T 28-03-2018 IPR004291 Transposase, IS66 A6A12_RS13645 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13007 Transposase C of IS166 homeodomain 42 111 2.7E-13 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain A6A12_RS13645 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13817 IS66 C-terminal element 473 509 3.3E-9 T 28-03-2018 A6A12_RS13645 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13005 zinc-finger binding domain of transposase IS66 119 163 1.7E-16 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 A6A12_RS13645 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF03050 Transposase IS66 family 183 466 1.5E-101 T 28-03-2018 IPR004291 Transposase, IS66 A6A12_RS00490 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13007 Transposase C of IS166 homeodomain 42 111 2.7E-13 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain A6A12_RS00490 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13817 IS66 C-terminal element 473 509 3.3E-9 T 28-03-2018 A6A12_RS00490 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13005 zinc-finger binding domain of transposase IS66 119 163 1.7E-16 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 A6A12_RS00490 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF03050 Transposase IS66 family 183 466 1.5E-101 T 28-03-2018 IPR004291 Transposase, IS66 A6A12_RS01420 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13007 Transposase C of IS166 homeodomain 42 111 2.7E-13 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain A6A12_RS01420 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13817 IS66 C-terminal element 473 509 3.3E-9 T 28-03-2018 A6A12_RS01420 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13005 zinc-finger binding domain of transposase IS66 119 163 1.7E-16 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 A6A12_RS01420 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF03050 Transposase IS66 family 183 466 1.5E-101 T 28-03-2018 IPR004291 Transposase, IS66 A6A12_RS08770 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13007 Transposase C of IS166 homeodomain 42 111 2.7E-13 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain A6A12_RS08770 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13817 IS66 C-terminal element 473 509 3.3E-9 T 28-03-2018 A6A12_RS08770 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF13005 zinc-finger binding domain of transposase IS66 119 163 1.7E-16 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 A6A12_RS08770 c724bd8a8dd9ccdd57a174973f1be31e 513 Pfam PF03050 Transposase IS66 family 183 466 1.5E-101 T 28-03-2018 IPR004291 Transposase, IS66 A6A12_RS01010 abbea21c3097e6ff6b1ea6de05662ca9 692 Gene3D G3DSA:1.10.150.20 1 59 6.4E-4 T 28-03-2018 A6A12_RS01010 abbea21c3097e6ff6b1ea6de05662ca9 692 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 28 663 1.1E-234 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 A6A12_RS01010 abbea21c3097e6ff6b1ea6de05662ca9 692 SMART SM00487 264 458 9.9E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS01010 abbea21c3097e6ff6b1ea6de05662ca9 692 Pfam PF00270 DEAD/DEAH box helicase 290 432 9.7E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A6A12_RS01010 abbea21c3097e6ff6b1ea6de05662ca9 692 SUPERFAMILY SSF52540 213 452 2.6E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01010 abbea21c3097e6ff6b1ea6de05662ca9 692 Pfam PF17191 RecG wedge domain 13 171 2.1E-20 T 28-03-2018 IPR033454 RecG, wedge domain A6A12_RS01010 abbea21c3097e6ff6b1ea6de05662ca9 692 Pfam PF00271 Helicase conserved C-terminal domain 480 587 2.9E-17 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS01010 abbea21c3097e6ff6b1ea6de05662ca9 692 Gene3D G3DSA:3.40.50.300 456 629 1.4E-27 T 28-03-2018 A6A12_RS01010 abbea21c3097e6ff6b1ea6de05662ca9 692 Gene3D G3DSA:2.40.50.140 60 142 2.1E-14 T 28-03-2018 A6A12_RS01010 abbea21c3097e6ff6b1ea6de05662ca9 692 Gene3D G3DSA:3.40.50.300 251 455 7.1E-35 T 28-03-2018 A6A12_RS01010 abbea21c3097e6ff6b1ea6de05662ca9 692 SMART SM00490 505 588 1.3E-21 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS01010 abbea21c3097e6ff6b1ea6de05662ca9 692 SUPERFAMILY SSF50249 8 173 7.54E-41 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS01010 abbea21c3097e6ff6b1ea6de05662ca9 692 SUPERFAMILY SSF52540 507 652 1.31E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01010 abbea21c3097e6ff6b1ea6de05662ca9 692 SUPERFAMILY SSF52540 291 341 1.31E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09595 82349b42a7149bdc9053e6282a38c340 353 SUPERFAMILY SSF52096 103 213 2.74E-30 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS09595 82349b42a7149bdc9053e6282a38c340 353 SUPERFAMILY SSF52096 244 303 2.74E-30 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS09595 82349b42a7149bdc9053e6282a38c340 353 Pfam PF01343 Peptidase family S49 166 314 5.6E-48 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 A6A12_RS09595 82349b42a7149bdc9053e6282a38c340 353 Pfam PF08496 Peptidase family S49 N-terminal 2 162 3.4E-56 T 28-03-2018 IPR013703 Peptidase S49, N-terminal proteobacteria GO:0004252|GO:0005886 A6A12_RS09595 82349b42a7149bdc9053e6282a38c340 353 Gene3D G3DSA:3.90.226.10 25 312 3.8E-31 T 28-03-2018 A6A12_RS10945 ce7f46360711b90946771059275f1931 156 SUPERFAMILY SSF52121 4 154 1.22E-60 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A6A12_RS10945 ce7f46360711b90946771059275f1931 156 Gene3D G3DSA:3.40.50.960 1 155 2.6E-63 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A6A12_RS10945 ce7f46360711b90946771059275f1931 156 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 151 2.3E-57 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A6A12_RS10945 ce7f46360711b90946771059275f1931 156 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 154 31.189 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A6A12_RS10945 ce7f46360711b90946771059275f1931 156 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 14 150 4.6E-55 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A6A12_RS14345 5751ddc1b74dea5269bf3024085bf841 140 Gene3D G3DSA:1.20.5.440 92 132 8.7E-11 T 28-03-2018 A6A12_RS14345 5751ddc1b74dea5269bf3024085bf841 140 SUPERFAMILY SSF46604 89 138 7.06E-14 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14345 5751ddc1b74dea5269bf3024085bf841 140 Gene3D G3DSA:2.60.15.10 2 91 6.4E-28 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14345 5751ddc1b74dea5269bf3024085bf841 140 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 134 6.6E-44 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14345 5751ddc1b74dea5269bf3024085bf841 140 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 4 132 20.834 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14345 5751ddc1b74dea5269bf3024085bf841 140 SUPERFAMILY SSF51344 5 87 2.35E-24 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14345 5751ddc1b74dea5269bf3024085bf841 140 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 11 88 8.0E-37 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14345 5751ddc1b74dea5269bf3024085bf841 140 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 85 1.2E-28 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14345 5751ddc1b74dea5269bf3024085bf841 140 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 89 134 1.5E-10 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS01620 24e5784461d0d5153f60f982eb756edf 191 Gene3D G3DSA:3.30.700.10 8 191 5.6E-15 T 28-03-2018 A6A12_RS01620 24e5784461d0d5153f60f982eb756edf 191 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS01620 24e5784461d0d5153f60f982eb756edf 191 Pfam PF07963 Prokaryotic N-terminal methylation motif 3 28 1.2E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS01620 24e5784461d0d5153f60f982eb756edf 191 SUPERFAMILY SSF54523 8 107 6.2E-13 T 28-03-2018 A6A12_RS01620 24e5784461d0d5153f60f982eb756edf 191 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 28 5.4E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS06420 d576f547d252a7e6ad59151597638620 396 Gene3D G3DSA:3.10.310.10 197 377 8.1E-68 T 28-03-2018 A6A12_RS06420 d576f547d252a7e6ad59151597638620 396 Gene3D G3DSA:3.10.310.10 10 196 2.6E-83 T 28-03-2018 A6A12_RS06420 d576f547d252a7e6ad59151597638620 396 SUPERFAMILY SSF54506 192 395 1.8E-73 T 28-03-2018 A6A12_RS06420 d576f547d252a7e6ad59151597638620 396 SUPERFAMILY SSF54506 12 189 4.32E-70 T 28-03-2018 A6A12_RS06420 d576f547d252a7e6ad59151597638620 396 Pfam PF04303 PrpF protein 14 395 3.0E-173 T 28-03-2018 IPR007400 PrpF protein A6A12_RS06420 d576f547d252a7e6ad59151597638620 396 TIGRFAM TIGR02334 prpF: probable AcnD-accessory protein PrpF 13 394 1.0E-219 T 28-03-2018 IPR012709 2-methyl-aconitate isomerase PrpF GO:0016853|GO:0019629 A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 SUPERFAMILY SSF52540 351 466 4.51E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 SUPERFAMILY SSF52540 15 345 1.75E-101 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 SMART SM00490 826 910 3.5E-19 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 Gene3D G3DSA:3.40.50.300 792 956 2.9E-25 T 28-03-2018 A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 Pfam PF02559 CarD-like/TRCF domain 480 575 1.4E-25 T 28-03-2018 IPR003711 CarD-like/TRCF domain A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 Pfam PF03461 TRCF domain 1010 1100 1.0E-27 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 SMART SM00487 600 790 2.4E-33 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 28 1141 28.843 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 148 1082 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 Gene3D G3DSA:3.30.2060.10 132 177 0.002 T 28-03-2018 A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 SUPERFAMILY SSF52540 523 783 2.9E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 SUPERFAMILY SSF141259 470 548 1.44E-24 T 28-03-2018 IPR003711 CarD-like/TRCF domain A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 Pfam PF00270 DEAD/DEAH box helicase 605 765 3.4E-21 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 Pfam PF00271 Helicase conserved C-terminal domain 805 909 5.7E-17 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 SMART SM01058 479 576 4.7E-52 T 28-03-2018 IPR003711 CarD-like/TRCF domain A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 Gene3D G3DSA:3.40.50.300 305 791 2.7E-41 T 28-03-2018 A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 SUPERFAMILY SSF52540 782 990 6.01E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 SMART SM00982 1008 1108 3.7E-46 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 A6A12_RS09040 dc5017bea37dedf38adfd4a5c624c2ed 1153 SUPERFAMILY SSF143517 995 1146 4.32E-42 T 28-03-2018 A6A12_RS13010 6f598bdf0c6d605503faf5356167ea98 303 PIRSF PIRSF000723 2 302 1.8E-115 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A6A12_RS13010 6f598bdf0c6d605503faf5356167ea98 303 Gene3D G3DSA:3.40.1160.10 2 302 8.5E-48 T 28-03-2018 A6A12_RS13010 6f598bdf0c6d605503faf5356167ea98 303 TIGRFAM TIGR00746 arcC: carbamate kinase 5 301 2.0E-120 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A6A12_RS13010 6f598bdf0c6d605503faf5356167ea98 303 PRINTS PR01469 Bacterial carbamate kinase signature 105 124 3.7E-62 T 28-03-2018 A6A12_RS13010 6f598bdf0c6d605503faf5356167ea98 303 PRINTS PR01469 Bacterial carbamate kinase signature 206 221 3.7E-62 T 28-03-2018 A6A12_RS13010 6f598bdf0c6d605503faf5356167ea98 303 PRINTS PR01469 Bacterial carbamate kinase signature 74 92 3.7E-62 T 28-03-2018 A6A12_RS13010 6f598bdf0c6d605503faf5356167ea98 303 PRINTS PR01469 Bacterial carbamate kinase signature 257 272 3.7E-62 T 28-03-2018 A6A12_RS13010 6f598bdf0c6d605503faf5356167ea98 303 PRINTS PR01469 Bacterial carbamate kinase signature 44 63 3.7E-62 T 28-03-2018 A6A12_RS13010 6f598bdf0c6d605503faf5356167ea98 303 PRINTS PR01469 Bacterial carbamate kinase signature 176 194 3.7E-62 T 28-03-2018 A6A12_RS13010 6f598bdf0c6d605503faf5356167ea98 303 PRINTS PR01469 Bacterial carbamate kinase signature 153 172 3.7E-62 T 28-03-2018 A6A12_RS13010 6f598bdf0c6d605503faf5356167ea98 303 Pfam PF00696 Amino acid kinase family 5 278 2.7E-29 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS13010 6f598bdf0c6d605503faf5356167ea98 303 SUPERFAMILY SSF53633 4 300 5.5E-78 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS13165 ae20213684a428360ee8b2d6d775da07 308 SUPERFAMILY SSF52283 31 114 1.25E-5 T 28-03-2018 A6A12_RS13165 ae20213684a428360ee8b2d6d775da07 308 Gene3D G3DSA:3.40.50.720 6 104 6.8E-12 T 28-03-2018 A6A12_RS13165 ae20213684a428360ee8b2d6d775da07 308 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 100 273 4.2E-46 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A6A12_RS13165 ae20213684a428360ee8b2d6d775da07 308 SUPERFAMILY SSF51735 93 274 1.81E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS13165 ae20213684a428360ee8b2d6d775da07 308 Gene3D G3DSA:3.40.50.720 105 274 3.1E-45 T 28-03-2018 A6A12_RS00585 c83240d2558fa5eea491976f38ab16c8 807 SMART SM00563 300 427 1.4E-27 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A6A12_RS00585 c83240d2558fa5eea491976f38ab16c8 807 PIRSF PIRSF500064 3 807 0.0 T 28-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 A6A12_RS00585 c83240d2558fa5eea491976f38ab16c8 807 PIRSF PIRSF000437 19 807 0.0 T 28-03-2018 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166 A6A12_RS00585 c83240d2558fa5eea491976f38ab16c8 807 Gene3D G3DSA:3.40.1130.10 235 528 8.2E-37 T 28-03-2018 A6A12_RS00585 c83240d2558fa5eea491976f38ab16c8 807 Hamap MF_00393 Glycerol-3-phosphate acyltransferase [plsB]. 13 807 31.891 T 28-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 A6A12_RS00585 c83240d2558fa5eea491976f38ab16c8 807 TIGRFAM TIGR03703 plsB: glycerol-3-phosphate O-acyltransferase 11 799 0.0 T 28-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 A6A12_RS00585 c83240d2558fa5eea491976f38ab16c8 807 Pfam PF01553 Acyltransferase 289 424 1.7E-23 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A6A12_RS00585 c83240d2558fa5eea491976f38ab16c8 807 SUPERFAMILY SSF69593 237 490 5.1E-27 T 28-03-2018 A6A12_RS13730 e5d7ab7253ddc8de0f49a5f271d873c0 610 Pfam PF00664 ABC transporter transmembrane region 42 308 1.1E-15 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A6A12_RS13730 e5d7ab7253ddc8de0f49a5f271d873c0 610 SUPERFAMILY SSF52540 351 601 4.55E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13730 e5d7ab7253ddc8de0f49a5f271d873c0 610 SMART SM00382 386 577 5.8E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS13730 e5d7ab7253ddc8de0f49a5f271d873c0 610 Pfam PF00005 ABC transporter 379 531 9.2E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS13730 e5d7ab7253ddc8de0f49a5f271d873c0 610 Gene3D G3DSA:3.40.50.300 347 604 5.5E-75 T 28-03-2018 A6A12_RS13730 e5d7ab7253ddc8de0f49a5f271d873c0 610 ProSitePatterns PS00211 ABC transporters family signature. 503 517 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS13730 e5d7ab7253ddc8de0f49a5f271d873c0 610 Gene3D G3DSA:1.20.1560.10 6 346 1.5E-31 T 28-03-2018 A6A12_RS13730 e5d7ab7253ddc8de0f49a5f271d873c0 610 SUPERFAMILY SSF90123 29 342 9.55E-47 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 Gene3D G3DSA:3.40.50.300 214 406 3.0E-50 T 28-03-2018 A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 Pfam PF00271 Helicase conserved C-terminal domain 231 334 5.5E-20 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 Pfam PF00570 HRDC domain 539 604 3.4E-22 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 Pfam PF09382 RQC domain 410 518 8.7E-38 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 Pfam PF16124 RecQ zinc-binding 347 408 1.6E-17 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 SUPERFAMILY SSF47819 535 610 1.05E-25 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 Gene3D G3DSA:1.10.10.10 407 526 2.1E-36 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 19 607 1.5E-250 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 19 467 4.4E-189 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 SUPERFAMILY SSF52540 212 460 5.14E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 SUPERFAMILY SSF52540 13 202 3.86E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 SMART SM00341 534 612 7.5E-22 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 Pfam PF00270 DEAD/DEAH box helicase 34 189 2.5E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 SMART SM00956 415 518 1.0E-50 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 Gene3D G3DSA:1.10.150.80 527 612 5.3E-27 T 28-03-2018 A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 SMART SM00490 254 335 1.6E-29 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 SMART SM00487 26 222 1.4E-25 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS13760 2c3896eee8e2011b9c4561383426f80a 612 Gene3D G3DSA:3.40.50.300 8 212 2.8E-32 T 28-03-2018 A6A12_RS09810 3df50bcbcdd4c6d8dbf50240029c8489 194 Gene3D G3DSA:1.10.287.990 20 82 4.8E-26 T 28-03-2018 A6A12_RS09810 3df50bcbcdd4c6d8dbf50240029c8489 194 SUPERFAMILY SSF54719 84 193 1.83E-42 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A6A12_RS09810 3df50bcbcdd4c6d8dbf50240029c8489 194 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.5E-21 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A6A12_RS09810 3df50bcbcdd4c6d8dbf50240029c8489 194 PRINTS PR01703 Manganese superoxide dismutase signature 156 168 1.5E-21 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A6A12_RS09810 3df50bcbcdd4c6d8dbf50240029c8489 194 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.5E-21 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A6A12_RS09810 3df50bcbcdd4c6d8dbf50240029c8489 194 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 1.5E-21 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A6A12_RS09810 3df50bcbcdd4c6d8dbf50240029c8489 194 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 1.5E-21 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A6A12_RS09810 3df50bcbcdd4c6d8dbf50240029c8489 194 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 82 2.8E-34 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A6A12_RS09810 3df50bcbcdd4c6d8dbf50240029c8489 194 PIRSF PIRSF000349 1 194 6.6E-83 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A6A12_RS09810 3df50bcbcdd4c6d8dbf50240029c8489 194 SUPERFAMILY SSF46609 1 84 4.06E-35 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A6A12_RS09810 3df50bcbcdd4c6d8dbf50240029c8489 194 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 190 1.2E-37 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A6A12_RS09810 3df50bcbcdd4c6d8dbf50240029c8489 194 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 158 165 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 A6A12_RS12815 c6cb512967229815234d73dcfc0d59a0 188 Gene3D G3DSA:2.30.30.30 4 63 2.5E-24 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 A6A12_RS12815 c6cb512967229815234d73dcfc0d59a0 188 SMART SM00841 131 186 5.1E-31 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A6A12_RS12815 c6cb512967229815234d73dcfc0d59a0 188 Gene3D G3DSA:2.40.50.140 131 186 3.1E-26 T 28-03-2018 A6A12_RS12815 c6cb512967229815234d73dcfc0d59a0 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 71 123 2.6E-22 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A6A12_RS12815 c6cb512967229815234d73dcfc0d59a0 188 SUPERFAMILY SSF50104 2 63 1.25E-20 T 28-03-2018 IPR008991 Translation protein SH3-like domain A6A12_RS12815 c6cb512967229815234d73dcfc0d59a0 188 SUPERFAMILY SSF50249 70 128 2.27E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS12815 c6cb512967229815234d73dcfc0d59a0 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 62 3.1E-25 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like A6A12_RS12815 c6cb512967229815234d73dcfc0d59a0 188 ProSitePatterns PS01275 Elongation factor P signature. 152 171 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site A6A12_RS12815 c6cb512967229815234d73dcfc0d59a0 188 Hamap MF_00141 Elongation factor P [efp]. 3 187 49.511 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A6A12_RS12815 c6cb512967229815234d73dcfc0d59a0 188 SUPERFAMILY SSF50249 130 187 1.11E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS12815 c6cb512967229815234d73dcfc0d59a0 188 TIGRFAM TIGR00038 efp: translation elongation factor P 5 187 1.8E-77 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 A6A12_RS12815 c6cb512967229815234d73dcfc0d59a0 188 SMART SM01185 69 123 3.9E-25 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A6A12_RS12815 c6cb512967229815234d73dcfc0d59a0 188 Gene3D G3DSA:2.40.50.140 67 129 1.3E-24 T 28-03-2018 A6A12_RS12815 c6cb512967229815234d73dcfc0d59a0 188 PIRSF PIRSF005901 2 188 2.3E-64 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP A6A12_RS12815 c6cb512967229815234d73dcfc0d59a0 188 Pfam PF09285 Elongation factor P, C-terminal 131 186 1.1E-24 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A6A12_RS00965 397ac4d09386b220ef579e1e6045d43c 245 PIRSF PIRSF028234 1 238 1.8E-106 T 28-03-2018 IPR016876 Uncharacterised conserved protein UCP028234 A6A12_RS00965 397ac4d09386b220ef579e1e6045d43c 245 Pfam PF12847 Methyltransferase domain 4 160 3.8E-20 T 28-03-2018 A6A12_RS00965 397ac4d09386b220ef579e1e6045d43c 245 Gene3D G3DSA:3.40.50.150 1 170 1.7E-11 T 28-03-2018 A6A12_RS00965 397ac4d09386b220ef579e1e6045d43c 245 SUPERFAMILY SSF53335 17 98 5.23E-9 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS02505 ee8abd251e1c50eff02a6f426eb46a9a 84 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 10 80 5.0E-18 T 28-03-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 A6A12_RS02505 ee8abd251e1c50eff02a6f426eb46a9a 84 Hamap MF_00404 Probable oxaloacetate decarboxylase gamma chain [oadG]. 1 84 33.515 T 28-03-2018 IPR023424 Oxaloacetate decarboxylase gamma chain, probable GO:0008948 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 A6A12_RS02505 ee8abd251e1c50eff02a6f426eb46a9a 84 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 5 82 5.7E-20 T 28-03-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 A6A12_RS06580 3e3cea971f2baf88838a87aa6b8f27d2 598 SUPERFAMILY SSF52540 355 592 2.87E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS06580 3e3cea971f2baf88838a87aa6b8f27d2 598 Pfam PF00664 ABC transporter transmembrane region 63 313 1.8E-32 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A6A12_RS06580 3e3cea971f2baf88838a87aa6b8f27d2 598 Pfam PF00005 ABC transporter 376 524 3.7E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS06580 3e3cea971f2baf88838a87aa6b8f27d2 598 SUPERFAMILY SSF90123 12 345 1.7E-57 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A6A12_RS06580 3e3cea971f2baf88838a87aa6b8f27d2 598 Gene3D G3DSA:1.20.1560.10 6 345 5.4E-47 T 28-03-2018 A6A12_RS06580 3e3cea971f2baf88838a87aa6b8f27d2 598 Gene3D G3DSA:3.40.50.300 347 597 1.7E-69 T 28-03-2018 A6A12_RS06580 3e3cea971f2baf88838a87aa6b8f27d2 598 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS06580 3e3cea971f2baf88838a87aa6b8f27d2 598 SMART SM00382 385 572 5.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS06450 6aadf8f2dbae553c44e55f29361349df 237 SUPERFAMILY SSF52402 7 220 1.9E-66 T 28-03-2018 A6A12_RS06450 6aadf8f2dbae553c44e55f29361349df 237 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 10 211 7.5E-82 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A6A12_RS06450 6aadf8f2dbae553c44e55f29361349df 237 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 8 224 51.47 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A6A12_RS06450 6aadf8f2dbae553c44e55f29361349df 237 Pfam PF06508 Queuosine biosynthesis protein QueC 9 218 7.3E-85 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A6A12_RS06450 6aadf8f2dbae553c44e55f29361349df 237 PIRSF PIRSF006293 6 231 1.9E-83 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A6A12_RS06450 6aadf8f2dbae553c44e55f29361349df 237 Gene3D G3DSA:3.40.50.620 7 236 3.4E-53 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS10020 a69b5ba8809c5af6235e0e347ea92496 588 PIRSF PIRSF000171 1 581 2.9E-53 T 28-03-2018 A6A12_RS10020 a69b5ba8809c5af6235e0e347ea92496 588 Gene3D G3DSA:4.10.80.40 541 588 1.9E-13 T 28-03-2018 A6A12_RS10020 a69b5ba8809c5af6235e0e347ea92496 588 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 43 52 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS10020 a69b5ba8809c5af6235e0e347ea92496 588 SUPERFAMILY SSF56425 237 356 1.79E-41 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS10020 a69b5ba8809c5af6235e0e347ea92496 588 Gene3D G3DSA:3.50.50.60 4 295 7.0E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS10020 a69b5ba8809c5af6235e0e347ea92496 588 Gene3D G3DSA:3.50.50.60 302 430 3.9E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS10020 a69b5ba8809c5af6235e0e347ea92496 588 Gene3D G3DSA:1.20.58.100 431 540 6.3E-37 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS10020 a69b5ba8809c5af6235e0e347ea92496 588 SUPERFAMILY SSF51905 359 444 3.38E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS10020 a69b5ba8809c5af6235e0e347ea92496 588 SUPERFAMILY SSF51905 5 259 3.38E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS10020 a69b5ba8809c5af6235e0e347ea92496 588 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 6 588 1.1E-276 T 28-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS10020 a69b5ba8809c5af6235e0e347ea92496 588 Pfam PF00890 FAD binding domain 9 405 3.1E-116 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS10020 a69b5ba8809c5af6235e0e347ea92496 588 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 9 588 6.0E-241 T 28-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS10020 a69b5ba8809c5af6235e0e347ea92496 588 SUPERFAMILY SSF46977 452 588 1.09E-48 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS10020 a69b5ba8809c5af6235e0e347ea92496 588 Pfam PF02910 Fumarate reductase flavoprotein C-term 460 588 2.1E-37 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS03960 fb193e9520783be979c2ec577d98b7f0 512 Hamap MF_02016 Membrane-bound lytic murein transglycosylase F [mltF]. 9 480 48.536 T 28-03-2018 IPR023703 Membrane-bound lytic murein transglycosylase F GO:0016837 A6A12_RS03960 fb193e9520783be979c2ec577d98b7f0 512 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 320 348 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 A6A12_RS03960 fb193e9520783be979c2ec577d98b7f0 512 Pfam PF01464 Transglycosylase SLT domain 309 413 3.4E-21 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 A6A12_RS03960 fb193e9520783be979c2ec577d98b7f0 512 SUPERFAMILY SSF53955 257 408 2.89E-37 T 28-03-2018 IPR023346 Lysozyme-like domain A6A12_RS03960 fb193e9520783be979c2ec577d98b7f0 512 SUPERFAMILY SSF53955 443 460 2.89E-37 T 28-03-2018 IPR023346 Lysozyme-like domain A6A12_RS03960 fb193e9520783be979c2ec577d98b7f0 512 Gene3D G3DSA:1.10.530.10 283 461 3.9E-36 T 28-03-2018 A6A12_RS03960 fb193e9520783be979c2ec577d98b7f0 512 Gene3D G3DSA:3.40.190.10 15 159 1.3E-19 T 28-03-2018 A6A12_RS03960 fb193e9520783be979c2ec577d98b7f0 512 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 278 1.1E-30 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS03960 fb193e9520783be979c2ec577d98b7f0 512 Gene3D G3DSA:3.40.190.10 160 280 5.0E-5 T 28-03-2018 A6A12_RS03960 fb193e9520783be979c2ec577d98b7f0 512 SMART SM00062 43 279 6.5E-27 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS03960 fb193e9520783be979c2ec577d98b7f0 512 SUPERFAMILY SSF53850 44 278 3.12E-35 T 28-03-2018 A6A12_RS01415 01bc3b95546867a5599af5a2ec41b24b 550 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 498 515 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01415 01bc3b95546867a5599af5a2ec41b24b 550 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 47 525 43.043 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01415 01bc3b95546867a5599af5a2ec41b24b 550 Gene3D G3DSA:3.40.50.10490 260 513 7.3E-127 T 28-03-2018 A6A12_RS01415 01bc3b95546867a5599af5a2ec41b24b 550 Gene3D G3DSA:3.40.50.10490 8 138 5.0E-42 T 28-03-2018 A6A12_RS01415 01bc3b95546867a5599af5a2ec41b24b 550 Gene3D G3DSA:3.40.50.10490 139 259 6.6E-54 T 28-03-2018 A6A12_RS01415 01bc3b95546867a5599af5a2ec41b24b 550 Gene3D G3DSA:1.10.1390.10 514 550 3.7E-21 T 28-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01415 01bc3b95546867a5599af5a2ec41b24b 550 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 266 279 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01415 01bc3b95546867a5599af5a2ec41b24b 550 Pfam PF00342 Phosphoglucose isomerase 53 542 3.7E-254 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01415 01bc3b95546867a5599af5a2ec41b24b 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 151 170 1.1E-56 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01415 01bc3b95546867a5599af5a2ec41b24b 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 339 360 1.1E-56 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01415 01bc3b95546867a5599af5a2ec41b24b 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 262 280 1.1E-56 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01415 01bc3b95546867a5599af5a2ec41b24b 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 498 511 1.1E-56 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01415 01bc3b95546867a5599af5a2ec41b24b 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 466 484 1.1E-56 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01415 01bc3b95546867a5599af5a2ec41b24b 550 PRINTS PR00662 Glucose-6-phosphate isomerase signature 484 498 1.1E-56 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01415 01bc3b95546867a5599af5a2ec41b24b 550 SUPERFAMILY SSF53697 6 548 1.97E-225 T 28-03-2018 A6A12_RS02560 09f543a7af36c4b9db2cb1c3f6dc2ddf 82 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 22.772 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02560 09f543a7af36c4b9db2cb1c3f6dc2ddf 82 Pfam PF00886 Ribosomal protein S16 8 68 6.2E-23 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02560 09f543a7af36c4b9db2cb1c3f6dc2ddf 82 Gene3D G3DSA:3.30.1320.10 1 79 4.0E-31 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02560 09f543a7af36c4b9db2cb1c3f6dc2ddf 82 ProSitePatterns PS00732 Ribosomal protein S16 signature. 2 11 - T 28-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS02560 09f543a7af36c4b9db2cb1c3f6dc2ddf 82 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 79 1.9E-26 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02560 09f543a7af36c4b9db2cb1c3f6dc2ddf 82 SUPERFAMILY SSF54565 1 76 1.7E-27 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS09705 00b79d9b48e04ba287f0d0084d1d7548 56 SUPERFAMILY SSF57829 2 55 1.16E-17 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A6A12_RS09705 00b79d9b48e04ba287f0d0084d1d7548 56 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.034 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS09705 00b79d9b48e04ba287f0d0084d1d7548 56 Pfam PF01783 Ribosomal L32p protein family 2 56 8.3E-20 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS09705 00b79d9b48e04ba287f0d0084d1d7548 56 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 3.4E-19 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS04590 48eaa30ca10a1b52f2fa06fbdc26b22b 308 Gene3D G3DSA:3.90.226.10 13 287 1.8E-66 T 28-03-2018 A6A12_RS04590 48eaa30ca10a1b52f2fa06fbdc26b22b 308 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 284 6.1E-139 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS04590 48eaa30ca10a1b52f2fa06fbdc26b22b 308 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 281 37.087 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS04590 48eaa30ca10a1b52f2fa06fbdc26b22b 308 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 251 260 2.2E-38 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS04590 48eaa30ca10a1b52f2fa06fbdc26b22b 308 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 181 2.2E-38 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS04590 48eaa30ca10a1b52f2fa06fbdc26b22b 308 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 143 2.2E-38 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS04590 48eaa30ca10a1b52f2fa06fbdc26b22b 308 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 200 217 2.2E-38 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS04590 48eaa30ca10a1b52f2fa06fbdc26b22b 308 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 229 240 2.2E-38 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS04590 48eaa30ca10a1b52f2fa06fbdc26b22b 308 SUPERFAMILY SSF52096 25 282 1.52E-83 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS04590 48eaa30ca10a1b52f2fa06fbdc26b22b 308 Pfam PF01039 Carboxyl transferase domain 100 239 3.4E-14 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 A6A12_RS01175 9c1961e8b9f4bc9d0884d1cdd29dac76 162 SUPERFAMILY SSF160369 4 158 1.57E-43 T 28-03-2018 A6A12_RS01175 9c1961e8b9f4bc9d0884d1cdd29dac76 162 Pfam PF00466 Ribosomal protein L10 5 100 3.1E-26 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 A6A12_RS01175 9c1961e8b9f4bc9d0884d1cdd29dac76 162 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 159 23.953 T 28-03-2018 IPR022973 Ribosomal protein L10 A6A12_RS01175 9c1961e8b9f4bc9d0884d1cdd29dac76 162 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS07705 b60362bfa0c2a112e1a4e0909a9d8d47 334 Gene3D G3DSA:3.40.50.880 11 229 2.4E-27 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS07705 b60362bfa0c2a112e1a4e0909a9d8d47 334 Gene3D G3DSA:1.10.10.60 230 272 2.2E-11 T 28-03-2018 A6A12_RS07705 b60362bfa0c2a112e1a4e0909a9d8d47 334 SMART SM00342 238 321 1.7E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A6A12_RS07705 b60362bfa0c2a112e1a4e0909a9d8d47 334 SUPERFAMILY SSF46689 274 325 3.19E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS07705 b60362bfa0c2a112e1a4e0909a9d8d47 334 SUPERFAMILY SSF46689 221 272 2.6E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS07705 b60362bfa0c2a112e1a4e0909a9d8d47 334 Pfam PF01965 DJ-1/PfpI family 15 142 6.3E-9 T 28-03-2018 IPR002818 DJ-1/PfpI A6A12_RS07705 b60362bfa0c2a112e1a4e0909a9d8d47 334 SUPERFAMILY SSF52317 10 192 3.21E-25 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS07705 b60362bfa0c2a112e1a4e0909a9d8d47 334 Gene3D G3DSA:1.10.10.60 273 328 4.7E-12 T 28-03-2018 A6A12_RS07705 b60362bfa0c2a112e1a4e0909a9d8d47 334 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 275 317 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A6A12_RS07705 b60362bfa0c2a112e1a4e0909a9d8d47 334 Pfam PF12833 Helix-turn-helix domain 245 322 5.2E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A6A12_RS09770 a67672314d505e4ff23df4bef84c4388 601 Pfam PF00884 Sulfatase 276 514 4.0E-26 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 A6A12_RS09770 a67672314d505e4ff23df4bef84c4388 601 Pfam PF11893 Domain of unknown function (DUF3413) 6 251 2.9E-97 T 28-03-2018 IPR024588 Inner membrane protein YejM, N-terminal A6A12_RS09770 a67672314d505e4ff23df4bef84c4388 601 SUPERFAMILY SSF53649 256 565 1.35E-49 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A6A12_RS09770 a67672314d505e4ff23df4bef84c4388 601 Gene3D G3DSA:3.40.720.10 255 544 1.7E-31 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A6A12_RS09770 a67672314d505e4ff23df4bef84c4388 601 PIRSF PIRSF004950 6 599 2.6E-237 T 28-03-2018 IPR012159 Inner membrane protein YejM A6A12_RS01930 f5a870ccff529727cedafa92daba75a6 345 Pfam PF00437 Type II/IV secretion system protein 12 271 3.1E-46 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A6A12_RS01930 f5a870ccff529727cedafa92daba75a6 345 SUPERFAMILY SSF52540 6 336 3.06E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01930 f5a870ccff529727cedafa92daba75a6 345 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A6A12_RS01930 f5a870ccff529727cedafa92daba75a6 345 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 336 1.7E-151 T 28-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 A6A12_RS01930 f5a870ccff529727cedafa92daba75a6 345 Gene3D G3DSA:3.40.50.300 274 343 3.1E-12 T 28-03-2018 A6A12_RS01930 f5a870ccff529727cedafa92daba75a6 345 Gene3D G3DSA:3.40.50.300 118 273 3.0E-29 T 28-03-2018 A6A12_RS01930 f5a870ccff529727cedafa92daba75a6 345 Gene3D G3DSA:3.30.450.90 1 100 2.3E-26 T 28-03-2018 A6A12_RS12220 fed0938cabb617cd87702adb0db92378 452 SUPERFAMILY SSF53623 97 308 8.77E-52 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS12220 fed0938cabb617cd87702adb0db92378 452 Gene3D G3DSA:3.90.190.20 314 452 1.4E-27 T 28-03-2018 A6A12_RS12220 fed0938cabb617cd87702adb0db92378 452 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 448 1.3E-261 T 28-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 A6A12_RS12220 fed0938cabb617cd87702adb0db92378 452 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 385 2.7E-10 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A6A12_RS12220 fed0938cabb617cd87702adb0db92378 452 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 449 59.068 T 28-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 A6A12_RS12220 fed0938cabb617cd87702adb0db92378 452 Gene3D G3DSA:3.40.50.720 1 90 1.7E-11 T 28-03-2018 A6A12_RS12220 fed0938cabb617cd87702adb0db92378 452 Gene3D G3DSA:3.40.1190.10 91 313 7.8E-42 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS12220 fed0938cabb617cd87702adb0db92378 452 SUPERFAMILY SSF53244 311 445 1.96E-38 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A6A12_RS12220 fed0938cabb617cd87702adb0db92378 452 Pfam PF01225 Mur ligase family, catalytic domain 2 101 2.9E-20 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A6A12_RS12220 fed0938cabb617cd87702adb0db92378 452 Pfam PF08245 Mur ligase middle domain 108 291 1.0E-21 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS12220 fed0938cabb617cd87702adb0db92378 452 SUPERFAMILY SSF51984 1 89 1.19E-23 T 28-03-2018 A6A12_RS11285 7945d6d6973e3b4d24bd7a59ceece425 781 Pfam PF07238 PilZ domain 469 553 1.2E-9 T 28-03-2018 IPR009875 PilZ domain GO:0035438 A6A12_RS11285 7945d6d6973e3b4d24bd7a59ceece425 781 Pfam PF07238 PilZ domain 144 232 2.3E-6 T 28-03-2018 IPR009875 PilZ domain GO:0035438 A6A12_RS11285 7945d6d6973e3b4d24bd7a59ceece425 781 SUPERFAMILY SSF141371 465 525 1.39E-6 T 28-03-2018 A6A12_RS11285 7945d6d6973e3b4d24bd7a59ceece425 781 Gene3D G3DSA:2.40.10.220 141 272 7.1E-10 T 28-03-2018 A6A12_RS11285 7945d6d6973e3b4d24bd7a59ceece425 781 Gene3D G3DSA:2.40.10.220 464 591 7.8E-13 T 28-03-2018 A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 Hamap MF_00505 Chaperone protein HtpG [htpG]. 7 632 32.268 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 SMART SM00387 32 189 6.7E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 SUPERFAMILY SSF110942 520 632 4.84E-33 T 28-03-2018 A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 SUPERFAMILY SSF54211 238 493 2.58E-98 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 PIRSF PIRSF002583 1 635 6.6E-214 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 Pfam PF00183 Hsp90 protein 227 632 3.1E-127 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 187 3.6E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 PRINTS PR00775 90kDa heat shock protein signature 195 213 1.6E-62 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 PRINTS PR00775 90kDa heat shock protein signature 125 147 1.6E-62 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 PRINTS PR00775 90kDa heat shock protein signature 31 53 1.6E-62 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 PRINTS PR00775 90kDa heat shock protein signature 98 115 1.6E-62 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 PRINTS PR00775 90kDa heat shock protein signature 10 30 1.6E-62 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 PRINTS PR00775 90kDa heat shock protein signature 80 97 1.6E-62 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 PRINTS PR00775 90kDa heat shock protein signature 177 194 1.6E-62 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 SUPERFAMILY SSF55874 10 218 2.62E-63 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 Gene3D G3DSA:3.30.565.10 1 231 2.0E-50 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 30 39 - T 28-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 A6A12_RS04525 3ad56adbf5edd4be493e035315e91db6 635 Gene3D G3DSA:3.40.50.2300 350 570 7.5E-4 T 28-03-2018 A6A12_RS06920 e7af870d9ca3e22e399da7538b094a59 182 Pfam PF01618 MotA/TolQ/ExbB proton channel family 71 175 4.8E-22 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 A6A12_RS01065 490b0d987b0548b291509dde4e80b633 89 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 80 4.1E-14 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A6A12_RS01065 490b0d987b0548b291509dde4e80b633 89 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A6A12_RS01065 490b0d987b0548b291509dde4e80b633 89 SUPERFAMILY SSF54292 1 87 1.02E-26 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A6A12_RS01065 490b0d987b0548b291509dde4e80b633 89 Gene3D G3DSA:3.10.20.30 1 89 1.1E-21 T 28-03-2018 IPR012675 Beta-grasp domain A6A12_RS02845 639dcdb363fc9bec7aaf81686b7c60b9 556 PIRSF PIRSF002741 4 539 7.4E-69 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A6A12_RS02845 639dcdb363fc9bec7aaf81686b7c60b9 556 Gene3D G3DSA:3.10.105.10 283 513 5.8E-52 T 28-03-2018 A6A12_RS02845 639dcdb363fc9bec7aaf81686b7c60b9 556 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 451 5.6E-76 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain A6A12_RS02845 639dcdb363fc9bec7aaf81686b7c60b9 556 Gene3D G3DSA:3.90.76.10 42 183 5.1E-30 T 28-03-2018 A6A12_RS02845 639dcdb363fc9bec7aaf81686b7c60b9 556 Gene3D G3DSA:3.40.190.10 184 282 4.6E-9 T 28-03-2018 A6A12_RS02845 639dcdb363fc9bec7aaf81686b7c60b9 556 SUPERFAMILY SSF53850 36 540 1.03E-105 T 28-03-2018 A6A12_RS02845 639dcdb363fc9bec7aaf81686b7c60b9 556 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 80 102 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site A6A12_RS03030 c5e654459b651a7ff60f22074c1a6836 167 SUPERFAMILY SSF55729 1 153 2.23E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS03030 c5e654459b651a7ff60f22074c1a6836 167 Gene3D G3DSA:3.40.630.30 1 143 9.7E-16 T 28-03-2018 A6A12_RS03030 c5e654459b651a7ff60f22074c1a6836 167 Pfam PF13527 Acetyltransferase (GNAT) domain 3 124 2.1E-8 T 28-03-2018 A6A12_RS11030 5c0c1d3c2818c82d3d47137334fa0e2f 247 Gene3D G3DSA:1.20.120.20 60 235 2.7E-4 T 28-03-2018 A6A12_RS11030 5c0c1d3c2818c82d3d47137334fa0e2f 247 Pfam PF11101 Protein of unknown function (DUF2884) 21 245 9.0E-70 T 28-03-2018 IPR021307 Protein of unknown function DUF2884 A6A12_RS01325 2f429d81be504cb809da300382c71ccb 75 Hamap MF_00715 Protein SlyX [slyX]. 8 75 17.052 T 28-03-2018 IPR007236 SlyX A6A12_RS01325 2f429d81be504cb809da300382c71ccb 75 Gene3D G3DSA:1.20.5.300 7 52 2.7E-15 T 28-03-2018 A6A12_RS01325 2f429d81be504cb809da300382c71ccb 75 Pfam PF04102 SlyX 9 75 2.4E-23 T 28-03-2018 IPR007236 SlyX A6A12_RS05235 382aeb7ef1dff8f2d917b17ceba8d1c6 91 Pfam PF06305 Lipopolysaccharide assembly protein A domain 22 84 8.5E-19 T 28-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 A6A12_RS05235 382aeb7ef1dff8f2d917b17ceba8d1c6 91 Hamap MF_01948 Lipopolysaccharide assembly protein A [lapA]. 1 90 19.907 T 28-03-2018 IPR032906 Lipopolysaccharide assembly protein A GO:0005886|GO:0008653 A6A12_RS00380 81166bb0943d0b5d0c76c1f9a2725b5c 104 SMART SM01219 1 104 1.2E-52 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 A6A12_RS00380 81166bb0943d0b5d0c76c1f9a2725b5c 104 SUPERFAMILY SSF55387 1 103 2.27E-38 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 A6A12_RS00380 81166bb0943d0b5d0c76c1f9a2725b5c 104 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 2 103 1.3E-41 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 A6A12_RS00380 81166bb0943d0b5d0c76c1f9a2725b5c 104 ProSitePatterns PS01344 Frataxin family signature. 48 62 - T 28-03-2018 IPR020895 Frataxin conserved site Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 A6A12_RS00380 81166bb0943d0b5d0c76c1f9a2725b5c 104 Hamap MF_00142 Protein CyaY [cyaY]. 1 103 26.889 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 A6A12_RS00380 81166bb0943d0b5d0c76c1f9a2725b5c 104 Gene3D G3DSA:3.30.920.10 1 104 1.6E-31 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 A6A12_RS00380 81166bb0943d0b5d0c76c1f9a2725b5c 104 Pfam PF01491 Frataxin-like domain 1 100 2.5E-29 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 694 30.243 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 SUPERFAMILY SSF50249 608 695 1.46E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 Pfam PF01138 3' exoribonuclease family, domain 1 17 145 1.3E-18 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 Pfam PF01138 3' exoribonuclease family, domain 1 325 457 1.9E-20 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 SUPERFAMILY SSF55666 451 550 1.31E-27 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 SUPERFAMILY SSF55666 146 236 1.23E-28 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 PIRSF PIRSF005499 3 707 4.8E-297 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 Gene3D G3DSA:1.10.10.400 254 317 5.1E-19 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 SUPERFAMILY SSF54211 299 493 2.18E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 Gene3D G3DSA:3.30.230.70 15 253 3.8E-52 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 SUPERFAMILY SSF46915 241 321 3.14E-18 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 SMART SM00316 621 691 7.4E-27 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 SMART SM00322 553 618 3.5E-12 T 28-03-2018 IPR004087 K Homology domain GO:0003676 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 Gene3D G3DSA:2.40.50.140 620 697 2.7E-25 T 28-03-2018 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 Pfam PF03725 3' exoribonuclease family, domain 2 148 211 8.5E-13 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 Gene3D G3DSA:3.30.1370.10 555 619 8.7E-15 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 SUPERFAMILY SSF54791 553 630 1.61E-16 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 243 321 1.3E-23 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 11 692 0.0 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 SUPERFAMILY SSF54211 6 145 1.32E-48 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 Pfam PF00575 S1 RNA binding domain 620 691 9.7E-20 T 28-03-2018 IPR003029 S1 domain GO:0003676 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 Pfam PF00013 KH domain 557 615 9.8E-10 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 A6A12_RS02990 791566f427b769b4864d4f987cfc986b 708 Gene3D G3DSA:3.30.230.70 318 545 1.4E-57 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A6A12_RS02745 823dce45f2a26324de9a6a13f9f07b4d 765 Pfam PF07244 Surface antigen variable number repeat 352 423 4.3E-7 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 A6A12_RS02745 823dce45f2a26324de9a6a13f9f07b4d 765 Gene3D G3DSA:2.40.160.50 393 765 1.1E-22 T 28-03-2018 A6A12_RS02745 823dce45f2a26324de9a6a13f9f07b4d 765 Gene3D G3DSA:3.40.1090.10 26 392 6.4E-47 T 28-03-2018 A6A12_RS02745 823dce45f2a26324de9a6a13f9f07b4d 765 SUPERFAMILY SSF52151 139 322 8.11E-57 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A6A12_RS02745 823dce45f2a26324de9a6a13f9f07b4d 765 SUPERFAMILY SSF52151 37 109 8.11E-57 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A6A12_RS02745 823dce45f2a26324de9a6a13f9f07b4d 765 Pfam PF01734 Patatin-like phospholipase 43 233 1.2E-30 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 A6A12_RS04335 bb1f6bdd5d388fb37576718e3a8bb93c 322 SMART SM00729 85 294 2.8E-18 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A6A12_RS04335 bb1f6bdd5d388fb37576718e3a8bb93c 322 TIGRFAM TIGR00510 lipA: lipoyl synthase 21 322 8.2E-148 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A6A12_RS04335 bb1f6bdd5d388fb37576718e3a8bb93c 322 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 18 74 1.0E-8 T 28-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A6A12_RS04335 bb1f6bdd5d388fb37576718e3a8bb93c 322 SUPERFAMILY SSF102114 53 317 5.36E-68 T 28-03-2018 A6A12_RS04335 bb1f6bdd5d388fb37576718e3a8bb93c 322 Gene3D G3DSA:3.20.20.70 26 305 5.3E-27 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS04335 bb1f6bdd5d388fb37576718e3a8bb93c 322 Hamap MF_00206 Lipoyl synthase [lipA]. 1 322 155.104 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A6A12_RS04335 bb1f6bdd5d388fb37576718e3a8bb93c 322 Pfam PF04055 Radical SAM superfamily 92 253 1.5E-18 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A6A12_RS04335 bb1f6bdd5d388fb37576718e3a8bb93c 322 PIRSF PIRSF005963 2 321 3.3E-130 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A6A12_RS05790 3fd42a9b8ac2993d946efea6f4866784 250 Pfam PF04288 MukE-like family 17 242 2.0E-119 T 28-03-2018 IPR007385 Prokaryotic chromosome segregation/condensation protein MukE GO:0005737|GO:0007059|GO:0030261 A6A12_RS05790 3fd42a9b8ac2993d946efea6f4866784 250 Hamap MF_01802 Chromosome partition protein MukE [mukE]. 17 247 49.753 T 28-03-2018 IPR007385 Prokaryotic chromosome segregation/condensation protein MukE GO:0005737|GO:0007059|GO:0030261 A6A12_RS10275 26aad75840c2a0fa8c12efeb410eb2b9 377 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 1.3E-43 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A6A12_RS10275 26aad75840c2a0fa8c12efeb410eb2b9 377 Pfam PF07196 Flagellin hook IN motif 194 246 6.7E-11 T 28-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 A6A12_RS10275 26aad75840c2a0fa8c12efeb410eb2b9 377 SUPERFAMILY SSF64518 1 377 2.88E-95 T 28-03-2018 A6A12_RS10275 26aad75840c2a0fa8c12efeb410eb2b9 377 Pfam PF00700 Bacterial flagellin C-terminal helical region 292 376 4.8E-23 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A6A12_RS10275 26aad75840c2a0fa8c12efeb410eb2b9 377 Gene3D G3DSA:1.20.1330.10 40 349 1.6E-70 T 28-03-2018 A6A12_RS10275 26aad75840c2a0fa8c12efeb410eb2b9 377 PRINTS PR00207 Flagellin signature 37 54 2.0E-25 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A6A12_RS10275 26aad75840c2a0fa8c12efeb410eb2b9 377 PRINTS PR00207 Flagellin signature 111 134 2.0E-25 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A6A12_RS10275 26aad75840c2a0fa8c12efeb410eb2b9 377 PRINTS PR00207 Flagellin signature 76 95 2.0E-25 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A6A12_RS13460 04696edb595824b959f97e2afecde34f 381 TIGRFAM TIGR02379 ECA_wecE: TDP-4-keto-6-deoxy-D-glucose transaminase 3 378 3.4E-216 T 28-03-2018 IPR012749 dTDP-4-amino-4,6-dideoxygalactose transaminase WecE-like MetaCyc: PWY-7315 A6A12_RS13460 04696edb595824b959f97e2afecde34f 381 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 15 371 1.0E-84 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A6A12_RS13460 04696edb595824b959f97e2afecde34f 381 PIRSF PIRSF000390 1 379 1.1E-109 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A6A12_RS13460 04696edb595824b959f97e2afecde34f 381 Gene3D G3DSA:3.40.640.10 2 244 3.7E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS13460 04696edb595824b959f97e2afecde34f 381 SUPERFAMILY SSF53383 3 379 9.32E-102 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS13460 04696edb595824b959f97e2afecde34f 381 Gene3D G3DSA:3.90.1150.10 245 380 3.9E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS12125 6b8a033f10b4336bf805ca94313f236b 265 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS12125 6b8a033f10b4336bf805ca94313f236b 265 SUPERFAMILY SSF52540 6 236 1.13E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12125 6b8a033f10b4336bf805ca94313f236b 265 Gene3D G3DSA:3.40.50.300 3 262 4.7E-63 T 28-03-2018 A6A12_RS12125 6b8a033f10b4336bf805ca94313f236b 265 SMART SM00382 31 228 1.8E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS12125 6b8a033f10b4336bf805ca94313f236b 265 Pfam PF00005 ABC transporter 23 170 5.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS01020 0f6457d926eeedeb8a5fcd49c49ba4d3 90 SMART SM01409 8 61 1.3E-16 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A6A12_RS01020 0f6457d926eeedeb8a5fcd49c49ba4d3 90 Gene3D G3DSA:3.90.940.10 1 90 2.3E-28 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A6A12_RS01020 0f6457d926eeedeb8a5fcd49c49ba4d3 90 SUPERFAMILY SSF63562 1 78 9.81E-26 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A6A12_RS01020 0f6457d926eeedeb8a5fcd49c49ba4d3 90 Pfam PF01192 RNA polymerase Rpb6 10 60 3.7E-18 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 A6A12_RS01020 0f6457d926eeedeb8a5fcd49c49ba4d3 90 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 59 1.8E-29 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01020 0f6457d926eeedeb8a5fcd49c49ba4d3 90 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 16.837 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS05320 ca942b9be799d3f4d233ed3fb40a0ac4 192 Gene3D G3DSA:3.50.70.10 32 173 1.3E-13 T 28-03-2018 IPR016088 Chalcone isomerase, 3-layer sandwich GO:0009813|GO:0045430 A6A12_RS05320 ca942b9be799d3f4d233ed3fb40a0ac4 192 Pfam PF16036 Chalcone isomerase-like 54 189 2.8E-8 T 28-03-2018 IPR016087 Chalcone isomerase GO:0016872 A6A12_RS07110 2bdae53b1cef7b1350d7215778583787 284 PIRSF PIRSF036628 11 279 1.4E-108 T 28-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 A6A12_RS07110 2bdae53b1cef7b1350d7215778583787 284 SUPERFAMILY SSF51182 11 263 4.31E-69 T 28-03-2018 IPR011051 RmlC-like cupin domain A6A12_RS07110 2bdae53b1cef7b1350d7215778583787 284 Gene3D G3DSA:2.60.120.10 133 278 6.3E-57 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS07110 2bdae53b1cef7b1350d7215778583787 284 Gene3D G3DSA:2.60.120.10 27 132 1.9E-34 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS07110 2bdae53b1cef7b1350d7215778583787 284 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 28 274 3.3E-98 T 28-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 A6A12_RS07110 2bdae53b1cef7b1350d7215778583787 284 Pfam PF04962 KduI/IolB family 16 274 1.4E-107 T 28-03-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 A6A12_RS02030 fc5a8377f8d888eb4999c5ae324fd801 621 Pfam PF13426 PAS domain 350 450 1.0E-9 T 28-03-2018 IPR000014 PAS domain A6A12_RS02030 fc5a8377f8d888eb4999c5ae324fd801 621 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 460 613 3.3E-39 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS02030 fc5a8377f8d888eb4999c5ae324fd801 621 SUPERFAMILY SSF103190 38 204 9.42E-32 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A6A12_RS02030 fc5a8377f8d888eb4999c5ae324fd801 621 Gene3D G3DSA:1.20.5.170 27 72 5.5E-18 T 28-03-2018 A6A12_RS02030 fc5a8377f8d888eb4999c5ae324fd801 621 Gene3D G3DSA:3.30.450.20 73 203 3.5E-26 T 28-03-2018 A6A12_RS02030 fc5a8377f8d888eb4999c5ae324fd801 621 SUPERFAMILY SSF103190 208 296 1.41E-15 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A6A12_RS02030 fc5a8377f8d888eb4999c5ae324fd801 621 Gene3D G3DSA:3.30.70.270 474 620 5.4E-43 T 28-03-2018 A6A12_RS02030 fc5a8377f8d888eb4999c5ae324fd801 621 Gene3D G3DSA:3.30.450.20 210 296 7.6E-13 T 28-03-2018 A6A12_RS02030 fc5a8377f8d888eb4999c5ae324fd801 621 SMART SM00267 451 614 2.2E-47 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS02030 fc5a8377f8d888eb4999c5ae324fd801 621 SUPERFAMILY SSF55073 467 614 1.26E-39 T 28-03-2018 IPR029787 Nucleotide cyclase A6A12_RS02030 fc5a8377f8d888eb4999c5ae324fd801 621 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 342 458 3.2E-12 T 28-03-2018 IPR000014 PAS domain A6A12_RS02030 fc5a8377f8d888eb4999c5ae324fd801 621 Pfam PF00990 Diguanylate cyclase, GGDEF domain 464 610 3.5E-37 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS02030 fc5a8377f8d888eb4999c5ae324fd801 621 Gene3D G3DSA:3.30.450.20 333 473 1.8E-18 T 28-03-2018 A6A12_RS02030 fc5a8377f8d888eb4999c5ae324fd801 621 SUPERFAMILY SSF55785 350 460 1.5E-14 T 28-03-2018 IPR000014 PAS domain A6A12_RS08905 96239922b80756d705d1b174cdde4b44 269 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 266 7.6E-103 T 28-03-2018 A6A12_RS08905 96239922b80756d705d1b174cdde4b44 269 Gene3D G3DSA:3.60.10.10 1 269 4.1E-52 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A6A12_RS08905 96239922b80756d705d1b174cdde4b44 269 ProSitePatterns PS00727 AP endonucleases family 1 signature 2. 198 214 - T 28-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 A6A12_RS08905 96239922b80756d705d1b174cdde4b44 269 SUPERFAMILY SSF56219 1 268 4.58E-88 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A6A12_RS08905 96239922b80756d705d1b174cdde4b44 269 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 260 2.1E-22 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A6A12_RS08905 96239922b80756d705d1b174cdde4b44 269 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 28-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 A6A12_RS08905 96239922b80756d705d1b174cdde4b44 269 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 267 1.3E-87 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 A6A12_RS10925 967fbf9639e6a58c5f19b48a29603fe4 127 ProDom PD080106 UPF0325 YAEH STRUCTURAL ECA1027 VV11856 YPTB3007 PBPRA2971 VV2560 VF1965 VC2264 1 126 2.0E-62 T 28-03-2018 IPR020911 Uncharacterised protein family UPF0325 A6A12_RS10925 967fbf9639e6a58c5f19b48a29603fe4 127 Pfam PF11944 Protein of unknown function (DUF3461) 1 126 7.1E-55 T 28-03-2018 IPR020911 Uncharacterised protein family UPF0325 A6A12_RS10925 967fbf9639e6a58c5f19b48a29603fe4 127 Hamap MF_01519 UPF0325 protein YaeH [yaeH]. 1 127 30.663 T 28-03-2018 IPR020911 Uncharacterised protein family UPF0325 A6A12_RS14145 eaaeaf382a6062ac61298992aad8d2be 503 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS14145 eaaeaf382a6062ac61298992aad8d2be 503 Pfam PF00005 ABC transporter 23 172 9.3E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS14145 eaaeaf382a6062ac61298992aad8d2be 503 Pfam PF00005 ABC transporter 275 427 2.5E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS14145 eaaeaf382a6062ac61298992aad8d2be 503 SUPERFAMILY SSF52540 274 489 1.97E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS14145 eaaeaf382a6062ac61298992aad8d2be 503 SUPERFAMILY SSF52540 8 224 1.25E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS14145 eaaeaf382a6062ac61298992aad8d2be 503 Gene3D G3DSA:3.40.50.300 4 236 2.6E-53 T 28-03-2018 A6A12_RS14145 eaaeaf382a6062ac61298992aad8d2be 503 Gene3D G3DSA:3.40.50.300 268 496 2.4E-37 T 28-03-2018 A6A12_RS14145 eaaeaf382a6062ac61298992aad8d2be 503 SMART SM00382 32 220 1.5E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS14145 eaaeaf382a6062ac61298992aad8d2be 503 SMART SM00382 281 476 1.3E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS04080 336fc262282fcbb19116446a6ada1939 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.7E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS04080 336fc262282fcbb19116446a6ada1939 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.7E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS04080 336fc262282fcbb19116446a6ada1939 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.7E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS04080 336fc262282fcbb19116446a6ada1939 303 Gene3D G3DSA:3.40.190.10 177 260 7.2E-22 T 28-03-2018 A6A12_RS04080 336fc262282fcbb19116446a6ada1939 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.3E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS04080 336fc262282fcbb19116446a6ada1939 303 Gene3D G3DSA:1.10.10.10 3 88 9.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS04080 336fc262282fcbb19116446a6ada1939 303 SUPERFAMILY SSF53850 92 295 1.81E-39 T 28-03-2018 A6A12_RS04080 336fc262282fcbb19116446a6ada1939 303 SUPERFAMILY SSF46785 3 85 6.39E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS04080 336fc262282fcbb19116446a6ada1939 303 Gene3D G3DSA:3.40.190.10 91 176 1.5E-17 T 28-03-2018 A6A12_RS04080 336fc262282fcbb19116446a6ada1939 303 Pfam PF03466 LysR substrate binding domain 91 291 2.5E-38 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS07000 2b5bfdc78f9c57a4c1b6dda1ed98817b 516 Gene3D G3DSA:1.10.1370.10 36 513 9.9E-28 T 28-03-2018 A6A12_RS07000 2b5bfdc78f9c57a4c1b6dda1ed98817b 516 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 330 349 2.1E-34 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A6A12_RS07000 2b5bfdc78f9c57a4c1b6dda1ed98817b 516 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 261 280 2.1E-34 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A6A12_RS07000 2b5bfdc78f9c57a4c1b6dda1ed98817b 516 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 241 260 2.1E-34 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A6A12_RS07000 2b5bfdc78f9c57a4c1b6dda1ed98817b 516 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 145 165 2.1E-34 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A6A12_RS07000 2b5bfdc78f9c57a4c1b6dda1ed98817b 516 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 288 304 2.1E-34 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A6A12_RS07000 2b5bfdc78f9c57a4c1b6dda1ed98817b 516 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 376 393 2.1E-34 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A6A12_RS07000 2b5bfdc78f9c57a4c1b6dda1ed98817b 516 SUPERFAMILY SSF55486 2 514 5.5E-90 T 28-03-2018 A6A12_RS07000 2b5bfdc78f9c57a4c1b6dda1ed98817b 516 PIRSF PIRSF006615 1 412 6.4E-158 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A6A12_RS07000 2b5bfdc78f9c57a4c1b6dda1ed98817b 516 PIRSF PIRSF006615 414 516 1.2E-41 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A6A12_RS07000 2b5bfdc78f9c57a4c1b6dda1ed98817b 516 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 9 409 2.3E-79 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A6A12_RS07000 2b5bfdc78f9c57a4c1b6dda1ed98817b 516 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 420 514 1.2E-17 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A6A12_RS05910 7feef8c93a452528344a2ec30b301faf 262 SMART SM00382 39 228 1.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS05910 7feef8c93a452528344a2ec30b301faf 262 Gene3D G3DSA:3.40.50.300 2 260 4.1E-63 T 28-03-2018 A6A12_RS05910 7feef8c93a452528344a2ec30b301faf 262 Pfam PF00005 ABC transporter 31 179 3.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS05910 7feef8c93a452528344a2ec30b301faf 262 SUPERFAMILY SSF52540 5 252 2.85E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 SUPERFAMILY SSF81923 4 156 8.54E-42 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 631 649 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 4.1E-14 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 6.9E-13 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 4.3E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 708 722 4.3E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 675 693 4.3E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 601 619 4.3E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 SUPERFAMILY SSF52540 159 545 1.11E-100 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 845 2.0E-25 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 Gene3D G3DSA:3.40.50.300 157 342 7.5E-27 T 28-03-2018 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 SMART SM00382 597 763 3.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 SMART SM00382 198 343 8.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 854 0.0 T 28-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 Gene3D G3DSA:1.10.8.60 766 858 1.8E-22 T 28-03-2018 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 Pfam PF07724 AAA domain (Cdc48 subfamily) 596 759 4.2E-57 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 SUPERFAMILY SSF52540 546 855 1.01E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 Gene3D G3DSA:1.10.8.60 343 547 1.7E-43 T 28-03-2018 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 Gene3D G3DSA:3.40.50.300 552 765 3.4E-53 T 28-03-2018 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 SMART SM01086 766 855 7.0E-35 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 334 2.9E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A6A12_RS03325 f4280874b315c11d2d73d42283262be8 858 Gene3D G3DSA:1.10.1780.10 1 151 2.1E-31 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 224 253 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 SUPERFAMILY SSF51230 102 189 5.76E-21 T 28-03-2018 IPR011053 Single hybrid motif A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 Gene3D G3DSA:4.10.320.10 313 375 5.2E-17 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 Pfam PF02817 e3 binding domain 320 354 1.3E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 25 54 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 Gene3D G3DSA:2.40.50.100 244 312 5.7E-9 T 28-03-2018 A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 125 154 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 SUPERFAMILY SSF51230 200 293 2.22E-23 T 28-03-2018 IPR011053 Single hybrid motif A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 SUPERFAMILY SSF52777 385 626 4.89E-81 T 28-03-2018 A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 396 626 6.7E-79 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 SUPERFAMILY SSF51230 1 89 1.14E-21 T 28-03-2018 IPR011053 Single hybrid motif A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 Gene3D G3DSA:3.90.1170.30 1 43 1.1E-8 T 28-03-2018 A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 Gene3D G3DSA:3.90.1170.30 44 143 2.1E-20 T 28-03-2018 A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 Gene3D G3DSA:3.90.1170.30 144 243 1.0E-19 T 28-03-2018 A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 SUPERFAMILY SSF47005 313 358 2.22E-12 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 Gene3D G3DSA:3.30.559.10 385 627 9.6E-79 T 28-03-2018 A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 182 627 7.5E-202 T 28-03-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 Pfam PF00364 Biotin-requiring enzyme 4 73 3.8E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 Pfam PF00364 Biotin-requiring enzyme 103 173 4.3E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment A6A12_RS02655 21457e30b79871e262e990c3c1c695f8 627 Pfam PF00364 Biotin-requiring enzyme 202 272 2.1E-21 T 28-03-2018 IPR000089 Biotin/lipoyl attachment A6A12_RS11075 459433f2b7f661b9dede130a5a19dd10 446 Hamap MF_00425 Na(+)-translocating NADH-quinone reductase subunit A [nqrA]. 1 446 46.14 T 28-03-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 A6A12_RS11075 459433f2b7f661b9dede130a5a19dd10 446 Pfam PF11973 NQRA C-terminal domain 261 309 5.6E-21 T 28-03-2018 IPR022615 Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain GO:0016655|GO:0055114 A6A12_RS11075 459433f2b7f661b9dede130a5a19dd10 446 Gene3D G3DSA:2.40.50.100 21 88 0.0018 T 28-03-2018 A6A12_RS11075 459433f2b7f661b9dede130a5a19dd10 446 TIGRFAM TIGR01936 nqrA: NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit 2 446 1.1E-202 T 28-03-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 A6A12_RS11075 459433f2b7f661b9dede130a5a19dd10 446 Pfam PF05896 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) 1 256 3.4E-113 T 28-03-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 A6A12_RS12900 e6b92e4f92883ce8fd07305e4de6d97b 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 A6A12_RS12900 e6b92e4f92883ce8fd07305e4de6d97b 335 Gene3D G3DSA:3.40.50.2300 55 175 3.2E-29 T 28-03-2018 A6A12_RS12900 e6b92e4f92883ce8fd07305e4de6d97b 335 SUPERFAMILY SSF53822 60 332 2.9E-89 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A6A12_RS12900 e6b92e4f92883ce8fd07305e4de6d97b 335 Pfam PF13377 Periplasmic binding protein-like domain 168 328 7.3E-41 T 28-03-2018 A6A12_RS12900 e6b92e4f92883ce8fd07305e4de6d97b 335 Gene3D G3DSA:3.40.50.2300 176 332 7.5E-49 T 28-03-2018 A6A12_RS12900 e6b92e4f92883ce8fd07305e4de6d97b 335 SUPERFAMILY SSF47413 1 59 3.47E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS12900 e6b92e4f92883ce8fd07305e4de6d97b 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 8.0E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS12900 e6b92e4f92883ce8fd07305e4de6d97b 335 Gene3D G3DSA:1.10.260.40 2 54 5.6E-22 T 28-03-2018 A6A12_RS12900 e6b92e4f92883ce8fd07305e4de6d97b 335 SMART SM00354 1 71 1.5E-32 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS09860 d72025a3121db3a96300c2a3b47752e8 250 Pfam PF01578 Cytochrome C assembly protein 31 184 4.8E-33 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A6A12_RS09860 d72025a3121db3a96300c2a3b47752e8 250 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 45 228 1.5E-86 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09860 d72025a3121db3a96300c2a3b47752e8 250 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 45 62 1.3E-65 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09860 d72025a3121db3a96300c2a3b47752e8 250 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 62 82 1.3E-65 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09860 d72025a3121db3a96300c2a3b47752e8 250 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 156 182 1.3E-65 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09860 d72025a3121db3a96300c2a3b47752e8 250 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 204 228 1.3E-65 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09860 d72025a3121db3a96300c2a3b47752e8 250 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 121 141 1.3E-65 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09860 d72025a3121db3a96300c2a3b47752e8 250 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 100 120 1.3E-65 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS13520 bf3a3b8dbcac88ff6b12ab0ca7c10338 224 Pfam PF04002 RadC-like JAB domain 103 222 5.5E-45 T 28-03-2018 IPR025657 RadC-like JAB domain A6A12_RS13520 bf3a3b8dbcac88ff6b12ab0ca7c10338 224 Gene3D G3DSA:1.10.150.20 45 92 0.0014 T 28-03-2018 A6A12_RS13520 bf3a3b8dbcac88ff6b12ab0ca7c10338 224 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 224 4.5E-78 T 28-03-2018 IPR001405 RadC protein A6A12_RS13520 bf3a3b8dbcac88ff6b12ab0ca7c10338 224 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site A6A12_RS13520 bf3a3b8dbcac88ff6b12ab0ca7c10338 224 SUPERFAMILY SSF47781 16 91 6.67E-11 T 28-03-2018 IPR010994 RuvA domain 2-like A6A12_RS13520 bf3a3b8dbcac88ff6b12ab0ca7c10338 224 SUPERFAMILY SSF102712 133 192 3.66E-5 T 28-03-2018 A6A12_RS13520 bf3a3b8dbcac88ff6b12ab0ca7c10338 224 Gene3D G3DSA:3.40.140.10 99 224 6.2E-48 T 28-03-2018 A6A12_RS09975 c0a91578adafcfbcfed96098a8f680b3 1120 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 1085 1100 2.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A6A12_RS09975 c0a91578adafcfbcfed96098a8f680b3 1120 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 1100 1116 2.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A6A12_RS09975 c0a91578adafcfbcfed96098a8f680b3 1120 SUPERFAMILY SSF101898 203 453 4.97E-12 T 28-03-2018 A6A12_RS09975 c0a91578adafcfbcfed96098a8f680b3 1120 Pfam PF12833 Helix-turn-helix domain 1041 1116 2.0E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A6A12_RS09975 c0a91578adafcfbcfed96098a8f680b3 1120 Gene3D G3DSA:1.10.10.60 1067 1119 5.8E-16 T 28-03-2018 A6A12_RS09975 c0a91578adafcfbcfed96098a8f680b3 1120 SUPERFAMILY SSF46689 1070 1117 1.21E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS09975 c0a91578adafcfbcfed96098a8f680b3 1120 SMART SM00342 1034 1116 5.8E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A6A12_RS09975 c0a91578adafcfbcfed96098a8f680b3 1120 SUPERFAMILY SSF101898 369 445 3.66E-7 T 28-03-2018 A6A12_RS09975 c0a91578adafcfbcfed96098a8f680b3 1120 SUPERFAMILY SSF101898 482 620 3.66E-7 T 28-03-2018 A6A12_RS09975 c0a91578adafcfbcfed96098a8f680b3 1120 Gene3D G3DSA:3.30.565.10 858 991 1.3E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09975 c0a91578adafcfbcfed96098a8f680b3 1120 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 1071 1112 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 A6A12_RS09975 c0a91578adafcfbcfed96098a8f680b3 1120 Gene3D G3DSA:1.10.10.60 1014 1066 4.6E-11 T 28-03-2018 A6A12_RS09975 c0a91578adafcfbcfed96098a8f680b3 1120 Gene3D G3DSA:2.130.10.10 240 378 6.1E-14 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A6A12_RS09975 c0a91578adafcfbcfed96098a8f680b3 1120 Gene3D G3DSA:2.130.10.10 49 237 0.11 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A6A12_RS09975 c0a91578adafcfbcfed96098a8f680b3 1120 Gene3D G3DSA:2.130.10.10 379 744 4.9E-11 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A6A12_RS03095 118f88d7724dda016936c8003dfff1c3 221 SUPERFAMILY SSF52980 3 220 4.4E-83 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A6A12_RS03095 118f88d7724dda016936c8003dfff1c3 221 Gene3D G3DSA:3.40.600.10 2 221 1.4E-57 T 28-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 A6A12_RS03095 118f88d7724dda016936c8003dfff1c3 221 TIGRFAM TIGR02248 mutH_TIGR: DNA mismatch repair endonuclease MutH 5 220 1.5E-102 T 28-03-2018 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 A6A12_RS03095 118f88d7724dda016936c8003dfff1c3 221 SMART SM00927 53 151 5.4E-65 T 28-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 A6A12_RS03095 118f88d7724dda016936c8003dfff1c3 221 Hamap MF_00759 DNA mismatch repair protein MutH [mutH]. 1 221 149.223 T 28-03-2018 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 A6A12_RS03095 118f88d7724dda016936c8003dfff1c3 221 Pfam PF02976 DNA mismatch repair enzyme MutH 53 151 4.7E-34 T 28-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 A6A12_RS04795 ce93844be36f214c1c99c7e929b8cb74 138 Pfam PF00571 CBS domain 6 61 3.8E-8 T 28-03-2018 IPR000644 CBS domain A6A12_RS04795 ce93844be36f214c1c99c7e929b8cb74 138 Pfam PF00571 CBS domain 73 126 2.0E-12 T 28-03-2018 IPR000644 CBS domain A6A12_RS04795 ce93844be36f214c1c99c7e929b8cb74 138 SMART SM00116 80 127 5.4E-8 T 28-03-2018 IPR000644 CBS domain A6A12_RS04795 ce93844be36f214c1c99c7e929b8cb74 138 SMART SM00116 13 61 0.013 T 28-03-2018 IPR000644 CBS domain A6A12_RS04795 ce93844be36f214c1c99c7e929b8cb74 138 Gene3D G3DSA:3.10.580.10 1 136 2.3E-28 T 28-03-2018 A6A12_RS04795 ce93844be36f214c1c99c7e929b8cb74 138 SUPERFAMILY SSF54631 2 126 1.52E-30 T 28-03-2018 A6A12_RS01565 b2e6ab21379d9b61e559cddc9bbd5ef5 177 Gene3D G3DSA:2.40.50.140 1 120 2.6E-45 T 28-03-2018 A6A12_RS01565 b2e6ab21379d9b61e559cddc9bbd5ef5 177 Pfam PF00436 Single-strand binding protein family 6 106 1.2E-42 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 A6A12_RS01565 b2e6ab21379d9b61e559cddc9bbd5ef5 177 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 177 7.3E-62 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A6A12_RS01565 b2e6ab21379d9b61e559cddc9bbd5ef5 177 PIRSF PIRSF002070 2 174 1.0E-36 T 28-03-2018 A6A12_RS01565 b2e6ab21379d9b61e559cddc9bbd5ef5 177 Hamap MF_00984 Single-stranded DNA-binding protein. 6 118 39.114 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 A6A12_RS01565 b2e6ab21379d9b61e559cddc9bbd5ef5 177 SUPERFAMILY SSF50249 4 177 7.88E-62 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS07575 0e02854d5366f8d4321b7cd5645157ec 327 SUPERFAMILY SSF52821 94 242 4.39E-31 T 28-03-2018 IPR001763 Rhodanese-like domain A6A12_RS07575 0e02854d5366f8d4321b7cd5645157ec 327 Pfam PF00581 Rhodanese-like domain 120 210 7.8E-8 T 28-03-2018 IPR001763 Rhodanese-like domain A6A12_RS07575 0e02854d5366f8d4321b7cd5645157ec 327 SMART SM00450 113 214 1.1E-22 T 28-03-2018 IPR001763 Rhodanese-like domain A6A12_RS07575 0e02854d5366f8d4321b7cd5645157ec 327 Gene3D G3DSA:3.40.250.10 107 324 3.2E-28 T 28-03-2018 IPR001763 Rhodanese-like domain A6A12_RS07575 0e02854d5366f8d4321b7cd5645157ec 327 Hamap MF_00469 UPF0176 protein YceA [yceA]. 2 254 44.218 T 28-03-2018 IPR020936 Uncharacterised protein family UPF0176 A6A12_RS09200 1ba3743b4657dcee18c27a3ff8fc290d 330 SMART SM00382 46 239 3.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS09200 1ba3743b4657dcee18c27a3ff8fc290d 330 Gene3D G3DSA:3.40.50.300 6 329 4.5E-82 T 28-03-2018 A6A12_RS09200 1ba3743b4657dcee18c27a3ff8fc290d 330 SUPERFAMILY SSF52540 8 261 4.36E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09200 1ba3743b4657dcee18c27a3ff8fc290d 330 Pfam PF00005 ABC transporter 38 189 1.8E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS09200 1ba3743b4657dcee18c27a3ff8fc290d 330 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS09200 1ba3743b4657dcee18c27a3ff8fc290d 330 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 308 3.8E-20 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A6A12_RS09200 1ba3743b4657dcee18c27a3ff8fc290d 330 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 240 326 9.0E-28 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A6A12_RS09495 2676464ca933fd659ccd856d7bc3cc75 153 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 1.2E-17 T 28-03-2018 A6A12_RS09495 2676464ca933fd659ccd856d7bc3cc75 153 Gene3D G3DSA:1.10.10.10 4 55 6.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09495 2676464ca933fd659ccd856d7bc3cc75 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 5.4E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A6A12_RS09495 2676464ca933fd659ccd856d7bc3cc75 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 5.4E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A6A12_RS09495 2676464ca933fd659ccd856d7bc3cc75 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 5.4E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A6A12_RS09495 2676464ca933fd659ccd856d7bc3cc75 153 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A6A12_RS09495 2676464ca933fd659ccd856d7bc3cc75 153 SUPERFAMILY SSF54909 63 152 2.86E-20 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel A6A12_RS09495 2676464ca933fd659ccd856d7bc3cc75 153 Pfam PF01037 Lrp/AsnC ligand binding domain 69 142 2.7E-20 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A6A12_RS09495 2676464ca933fd659ccd856d7bc3cc75 153 SUPERFAMILY SSF46785 2 88 4.45E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09495 2676464ca933fd659ccd856d7bc3cc75 153 Gene3D G3DSA:3.30.70.920 56 149 1.7E-25 T 28-03-2018 A6A12_RS09495 2676464ca933fd659ccd856d7bc3cc75 153 SMART SM00344 3 112 1.0E-44 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A6A12_RS12690 cc5838b3a5925b2fbbdc9c3b632c9e56 173 Pfam PF04351 Pilus assembly protein, PilP 27 172 3.6E-43 T 28-03-2018 IPR007446 Pilus assembly protein PilP A6A12_RS12690 cc5838b3a5925b2fbbdc9c3b632c9e56 173 PIRSF PIRSF016481 1 173 2.6E-58 T 28-03-2018 IPR007446 Pilus assembly protein PilP A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 Pfam PF14520 Helix-hairpin-helix domain 432 486 2.8E-9 T 28-03-2018 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 365 414 1.5E-19 T 28-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 440 489 6.2E-18 T 28-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 Gene3D G3DSA:3.30.300.20 278 348 9.1E-13 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 Gene3D G3DSA:3.30.300.20 199 276 2.2E-32 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 Pfam PF13184 NusA-like KH domain 230 297 7.2E-28 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 SUPERFAMILY SSF47794 429 491 9.73E-17 T 28-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 SMART SM00322 230 293 17.0 T 28-03-2018 IPR004087 K Homology domain GO:0003676 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 SMART SM00322 301 375 0.015 T 28-03-2018 IPR004087 K Homology domain GO:0003676 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 SUPERFAMILY SSF54814 201 278 1.37E-28 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 Gene3D G3DSA:1.10.150.20 428 495 4.2E-15 T 28-03-2018 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 Gene3D G3DSA:1.10.150.20 352 421 1.9E-14 T 28-03-2018 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 SUPERFAMILY SSF54814 279 342 5.04E-15 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 SUPERFAMILY SSF50249 132 199 6.35E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 Pfam PF08529 NusA N-terminal domain 4 123 1.6E-33 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 Gene3D G3DSA:2.40.50.140 135 198 2.4E-12 T 28-03-2018 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 342 9.8E-125 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 SUPERFAMILY SSF47794 349 414 2.2E-15 T 28-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 410 28.784 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 SMART SM00316 133 198 3.6E-7 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 SUPERFAMILY SSF69705 1 126 2.35E-38 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A6A12_RS02965 1752053d6495e4112793f70d3689e115 495 Gene3D G3DSA:3.30.1480.10 1 129 1.4E-42 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 Hamap MF_01498 DNA repair protein RadA [radA]. 21 457 42.75 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 Pfam PF13481 AAA domain 85 224 1.7E-13 T 28-03-2018 A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 PRINTS PR01874 DNA repair protein radA signature 10 34 1.0E-93 T 28-03-2018 A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 PRINTS PR01874 DNA repair protein radA signature 176 200 1.0E-93 T 28-03-2018 A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 PRINTS PR01874 DNA repair protein radA signature 215 243 1.0E-93 T 28-03-2018 A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 PRINTS PR01874 DNA repair protein radA signature 324 347 1.0E-93 T 28-03-2018 A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 PRINTS PR01874 DNA repair protein radA signature 85 113 1.0E-93 T 28-03-2018 A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 PRINTS PR01874 DNA repair protein radA signature 126 143 1.0E-93 T 28-03-2018 A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 PRINTS PR01874 DNA repair protein radA signature 250 276 1.0E-93 T 28-03-2018 A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 SMART SM00382 93 246 5.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 Gene3D G3DSA:3.40.50.300 56 253 7.6E-19 T 28-03-2018 A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 453 3.8E-223 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 SUPERFAMILY SSF52540 70 295 4.46E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 SUPERFAMILY SSF54211 305 456 1.93E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 SUPERFAMILY SSF54211 257 271 1.93E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 Pfam PF13541 Subunit ChlI of Mg-chelatase 347 432 2.8E-9 T 28-03-2018 A6A12_RS11280 e8a3658aafe2bdf7f46462010dcf6437 459 Gene3D G3DSA:3.30.230.10 254 459 2.7E-47 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A6A12_RS12175 331f92a9d70191cd099ec82535ae031f 285 Pfam PF03668 P-loop ATPase protein family 1 284 3.0E-112 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 A6A12_RS12175 331f92a9d70191cd099ec82535ae031f 285 PIRSF PIRSF005052 1 285 8.2E-108 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 A6A12_RS12175 331f92a9d70191cd099ec82535ae031f 285 SUPERFAMILY SSF52540 1 152 3.59E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12175 331f92a9d70191cd099ec82535ae031f 285 Gene3D G3DSA:3.40.50.300 1 155 3.4E-14 T 28-03-2018 A6A12_RS12175 331f92a9d70191cd099ec82535ae031f 285 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 283 41.212 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 Gene3D G3DSA:3.40.50.140 1 170 4.6E-49 T 28-03-2018 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 Gene3D G3DSA:2.20.25.10 814 868 1.3E-25 T 28-03-2018 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 SMART SM00436 140 228 2.7E-46 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 640 2.4E-247 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 Pfam PF08272 Topoisomerase I zinc-ribbon-like 762 798 5.8E-11 T 28-03-2018 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 Pfam PF08272 Topoisomerase I zinc-ribbon-like 831 868 2.7E-16 T 28-03-2018 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 Pfam PF01751 Toprim domain 5 149 3.2E-31 T 28-03-2018 IPR006171 TOPRIM domain A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 Gene3D G3DSA:2.70.20.10 353 470 6.2E-36 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 Gene3D G3DSA:1.10.460.10 171 349 7.0E-45 T 28-03-2018 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 Gene3D G3DSA:1.10.460.10 471 589 1.4E-25 T 28-03-2018 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 728 53.793 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 SUPERFAMILY SSF56712 3 615 3.66E-197 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 713 749 7.2E-9 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 603 628 7.8E-5 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 SUPERFAMILY SSF57783 814 870 1.24E-20 T 28-03-2018 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 Pfam PF01131 DNA topoisomerase 164 571 1.2E-126 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 SUPERFAMILY SSF57783 705 747 1.11E-5 T 28-03-2018 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 316 330 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 SMART SM00437 279 533 2.3E-116 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 198 216 6.0E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 321 330 6.0E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 397 413 6.0E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 113 126 6.0E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 496 510 6.0E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 SMART SM00493 3 139 2.6E-30 T 28-03-2018 IPR006171 TOPRIM domain A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 SUPERFAMILY SSF57783 750 812 1.62E-19 T 28-03-2018 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 Gene3D G3DSA:3.30.65.10 590 650 1.0E-10 T 28-03-2018 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 Gene3D G3DSA:3.30.65.10 700 749 1.5E-8 T 28-03-2018 A6A12_RS05725 969975d37d1b4cfb47bdc9755e42003a 876 Gene3D G3DSA:3.30.65.10 750 812 2.1E-10 T 28-03-2018 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 770 877 6.4E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 Gene3D G3DSA:1.20.120.160 1096 1184 6.4E-5 T 28-03-2018 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 SMART SM00062 60 259 4.6E-4 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 SMART SM00062 274 484 0.0053 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 PRINTS PR00344 Bacterial sensor protein C-terminal signature 823 833 1.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 PRINTS PR00344 Bacterial sensor protein C-terminal signature 840 858 1.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 PRINTS PR00344 Bacterial sensor protein C-terminal signature 805 819 1.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 PRINTS PR00344 Bacterial sensor protein C-terminal signature 864 877 1.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 SUPERFAMILY SSF52172 956 1082 3.42E-29 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 SUPERFAMILY SSF47384 643 723 1.0E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 SMART SM00387 769 880 1.7E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 SUPERFAMILY SSF53850 276 481 5.0E-21 T 28-03-2018 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 Pfam PF00512 His Kinase A (phospho-acceptor) domain 658 721 1.1E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 Pfam PF00072 Response regulator receiver domain 957 1071 1.9E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 Gene3D G3DSA:3.30.565.10 717 880 9.0E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 Gene3D G3DSA:3.40.50.2300 938 1086 2.9E-28 T 28-03-2018 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 Gene3D G3DSA:3.40.190.10 263 411 2.5E-11 T 28-03-2018 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 Gene3D G3DSA:3.40.190.10 30 192 1.7E-12 T 28-03-2018 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 SUPERFAMILY SSF47226 1106 1181 1.19E-6 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 Gene3D G3DSA:1.10.287.130 662 716 1.6E-13 T 28-03-2018 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 SMART SM00448 955 1071 4.3E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 SUPERFAMILY SSF55874 712 878 1.31E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 61 249 2.3E-18 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 278 481 2.0E-12 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 Gene3D G3DSA:3.30.450.20 412 661 1.5E-7 T 28-03-2018 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 SUPERFAMILY SSF53850 7 249 1.16E-22 T 28-03-2018 A6A12_RS09230 c1f850cca66bef018898465ba831ae9e 1188 SMART SM00388 657 722 5.6E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS04545 2cb7b543f25a9b79839e8f21af384d94 166 Pfam PF02357 Transcription termination factor nusG 2 97 1.3E-19 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A6A12_RS04545 2cb7b543f25a9b79839e8f21af384d94 166 SMART SM00738 1 101 4.9E-27 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A6A12_RS04545 2cb7b543f25a9b79839e8f21af384d94 166 Hamap MF_00951 Transcription antitermination protein RfaH [rfaH]. 1 165 44.863 T 28-03-2018 IPR010215 Transcription antitermination protein RfaH GO:0006355 A6A12_RS04545 2cb7b543f25a9b79839e8f21af384d94 166 Gene3D G3DSA:3.30.70.940 1 104 9.8E-20 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A6A12_RS04545 2cb7b543f25a9b79839e8f21af384d94 166 SUPERFAMILY SSF82679 1 99 2.22E-28 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A6A12_RS04545 2cb7b543f25a9b79839e8f21af384d94 166 TIGRFAM TIGR01955 RfaH: transcription elongation factor/antiterminator RfaH 4 162 1.2E-60 T 28-03-2018 IPR010215 Transcription antitermination protein RfaH GO:0006355 A6A12_RS05330 4ea9ad1d5865207c433b5bdb3df24587 768 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 24 636 5.8E-261 T 28-03-2018 IPR022946 Uncharacterised protein family UPF0313 A6A12_RS05330 4ea9ad1d5865207c433b5bdb3df24587 768 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 24 638 48.577 T 28-03-2018 IPR022946 Uncharacterised protein family UPF0313 A6A12_RS05330 4ea9ad1d5865207c433b5bdb3df24587 768 SMART SM00729 367 617 1.0E-4 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A6A12_RS05330 4ea9ad1d5865207c433b5bdb3df24587 768 Pfam PF04055 Radical SAM superfamily 371 576 1.8E-19 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A6A12_RS05330 4ea9ad1d5865207c433b5bdb3df24587 768 Gene3D G3DSA:3.20.20.70 261 739 1.2E-30 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS05330 4ea9ad1d5865207c433b5bdb3df24587 768 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 371 391 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A6A12_RS05330 4ea9ad1d5865207c433b5bdb3df24587 768 Pfam PF08497 Radical SAM N-terminal 24 370 6.8E-141 T 28-03-2018 IPR013704 Uncharacterised protein family UPF0313, N-terminal A6A12_RS05330 4ea9ad1d5865207c433b5bdb3df24587 768 Pfam PF11842 Domain of unknown function (DUF3362) 585 726 3.1E-42 T 28-03-2018 IPR024560 Uncharacterised protein family UPF0313, C-terminal A6A12_RS05330 4ea9ad1d5865207c433b5bdb3df24587 768 SUPERFAMILY SSF102114 370 431 5.23E-11 T 28-03-2018 A6A12_RS05330 4ea9ad1d5865207c433b5bdb3df24587 768 SUPERFAMILY SSF102114 461 642 5.23E-11 T 28-03-2018 A6A12_RS09065 5022ca14bab832b7e221e22d435cf294 289 Pfam PF01636 Phosphotransferase enzyme family 38 237 3.2E-13 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase A6A12_RS09065 5022ca14bab832b7e221e22d435cf294 289 Gene3D G3DSA:3.90.1200.10 64 280 1.0E-18 T 28-03-2018 A6A12_RS09065 5022ca14bab832b7e221e22d435cf294 289 SUPERFAMILY SSF56112 37 276 9.04E-33 T 28-03-2018 IPR011009 Protein kinase-like domain A6A12_RS00110 c5750c81624a511016f77e70948322bd 315 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 5.0E-48 T 28-03-2018 A6A12_RS00110 c5750c81624a511016f77e70948322bd 315 Gene3D G3DSA:3.40.50.300 185 313 2.4E-14 T 28-03-2018 A6A12_RS00110 c5750c81624a511016f77e70948322bd 315 Pfam PF01078 Magnesium chelatase, subunit ChlI 190 308 2.5E-53 T 28-03-2018 IPR000523 Magnesium chelatase ChlI domain A6A12_RS00110 c5750c81624a511016f77e70948322bd 315 Gene3D G3DSA:3.30.230.10 3 184 4.6E-43 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A6A12_RS00110 c5750c81624a511016f77e70948322bd 315 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 307 1.1E-133 T 28-03-2018 IPR004482 Mg chelatase-related protein A6A12_RS00110 c5750c81624a511016f77e70948322bd 315 SUPERFAMILY SSF52540 189 307 1.25E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS00110 c5750c81624a511016f77e70948322bd 315 SUPERFAMILY SSF54211 2 169 6.45E-34 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS05930 16a59de496b5eb0aef368cd1a8fe6b30 539 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 77 455 4.3E-83 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain A6A12_RS05930 16a59de496b5eb0aef368cd1a8fe6b30 539 Gene3D G3DSA:3.90.76.10 41 206 5.0E-34 T 28-03-2018 A6A12_RS05930 16a59de496b5eb0aef368cd1a8fe6b30 539 PIRSF PIRSF002741 1 539 7.5E-91 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A6A12_RS05930 16a59de496b5eb0aef368cd1a8fe6b30 539 SUPERFAMILY SSF53850 34 535 1.57E-129 T 28-03-2018 A6A12_RS05930 16a59de496b5eb0aef368cd1a8fe6b30 539 Gene3D G3DSA:3.40.190.10 207 302 3.2E-20 T 28-03-2018 A6A12_RS05930 16a59de496b5eb0aef368cd1a8fe6b30 539 Gene3D G3DSA:3.10.105.10 303 509 4.1E-53 T 28-03-2018 A6A12_RS06640 f95c7f2023425c65607608435225f72e 638 Pfam PF16326 ABC transporter C-terminal domain 564 632 5.2E-17 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 A6A12_RS06640 f95c7f2023425c65607608435225f72e 638 Gene3D G3DSA:3.40.50.300 285 551 2.5E-57 T 28-03-2018 A6A12_RS06640 f95c7f2023425c65607608435225f72e 638 SUPERFAMILY SSF52540 5 239 5.7E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS06640 f95c7f2023425c65607608435225f72e 638 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS06640 f95c7f2023425c65607608435225f72e 638 Pfam PF00005 ABC transporter 336 469 2.5E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS06640 f95c7f2023425c65607608435225f72e 638 Pfam PF00005 ABC transporter 19 185 4.9E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS06640 f95c7f2023425c65607608435225f72e 638 SMART SM00382 28 230 3.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS06640 f95c7f2023425c65607608435225f72e 638 SMART SM00382 344 514 2.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS06640 f95c7f2023425c65607608435225f72e 638 Gene3D G3DSA:3.40.50.300 1 284 2.4E-51 T 28-03-2018 A6A12_RS06640 f95c7f2023425c65607608435225f72e 638 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS06640 f95c7f2023425c65607608435225f72e 638 SUPERFAMILY SSF52540 311 524 1.43E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS06640 f95c7f2023425c65607608435225f72e 638 Pfam PF12848 ABC transporter 224 296 2.8E-11 T 28-03-2018 IPR032781 ABC-transporter extension domain A6A12_RS06890 2b27f07da4b216b2f86c74732d5c7815 465 PIRSF PIRSF006603 14 460 2.5E-58 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS06890 2b27f07da4b216b2f86c74732d5c7815 465 Pfam PF01554 MatE 26 185 3.2E-33 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS06890 2b27f07da4b216b2f86c74732d5c7815 465 Pfam PF01554 MatE 252 413 4.7E-34 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS06890 2b27f07da4b216b2f86c74732d5c7815 465 TIGRFAM TIGR00797 matE: MATE efflux family protein 26 430 3.3E-114 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS09645 ade6650cae49cc8f85a341af9dc419bb 476 Gene3D G3DSA:3.30.1360.60 397 472 4.4E-26 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A6A12_RS09645 ade6650cae49cc8f85a341af9dc419bb 476 Pfam PF02378 Phosphotransferase system, EIIC 13 318 3.1E-74 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A6A12_RS09645 ade6650cae49cc8f85a341af9dc419bb 476 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 377 458 4.2E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A6A12_RS09645 ade6650cae49cc8f85a341af9dc419bb 476 SUPERFAMILY SSF55604 399 472 3.79E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A6A12_RS09645 ade6650cae49cc8f85a341af9dc419bb 476 Pfam PF00367 phosphotransferase system, EIIB 402 434 2.3E-12 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A6A12_RS09645 ade6650cae49cc8f85a341af9dc419bb 476 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 473 7.6E-199 T 28-03-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0015758|GO:0016021 A6A12_RS12970 ee754d4e4550cbaadf67ca8aa0e7462e 466 Gene3D G3DSA:1.10.287.130 240 308 6.3E-12 T 28-03-2018 A6A12_RS12970 ee754d4e4550cbaadf67ca8aa0e7462e 466 Pfam PF00672 HAMP domain 197 244 3.8E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS12970 ee754d4e4550cbaadf67ca8aa0e7462e 466 SUPERFAMILY SSF47384 236 312 1.45E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS12970 ee754d4e4550cbaadf67ca8aa0e7462e 466 SUPERFAMILY SSF55874 302 464 2.62E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS12970 ee754d4e4550cbaadf67ca8aa0e7462e 466 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 465 6.5E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS12970 ee754d4e4550cbaadf67ca8aa0e7462e 466 Gene3D G3DSA:3.30.565.10 315 466 4.0E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS12970 ee754d4e4550cbaadf67ca8aa0e7462e 466 SMART SM00387 356 466 2.7E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS12970 ee754d4e4550cbaadf67ca8aa0e7462e 466 SMART SM00388 250 312 6.2E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS12970 ee754d4e4550cbaadf67ca8aa0e7462e 466 Pfam PF16527 Two-component sensor protein CpxA, periplasmic domain 36 174 2.4E-60 T 28-03-2018 IPR032404 Two-component sensor protein CpxA, periplasmic domain A6A12_RS12970 ee754d4e4550cbaadf67ca8aa0e7462e 466 Pfam PF00512 His Kinase A (phospho-acceptor) domain 252 311 2.7E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS12970 ee754d4e4550cbaadf67ca8aa0e7462e 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 405 1.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS12970 ee754d4e4550cbaadf67ca8aa0e7462e 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 419 1.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS12970 ee754d4e4550cbaadf67ca8aa0e7462e 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 1.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS12970 ee754d4e4550cbaadf67ca8aa0e7462e 466 SMART SM00304 196 249 6.1E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 5 529 0.0 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 SUPERFAMILY SSF54980 393 468 3.02E-17 T 28-03-2018 IPR035647 EF-G domain III/V-like A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 SUPERFAMILY SSF50447 262 393 2.59E-26 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 Pfam PF16658 Class II release factor RF3, C-terminal domain 387 514 2.1E-46 T 28-03-2018 IPR032090 Peptide chain release factor 3, C-terminal A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 Gene3D G3DSA:3.40.50.300 8 284 1.2E-34 T 28-03-2018 A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 160 1.6E-19 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 Pfam PF03144 Elongation factor Tu domain 2 314 380 1.3E-7 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 Gene3D G3DSA:3.30.70.870 392 465 4.1E-10 T 28-03-2018 A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 4 527 51.88 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 Gene3D G3DSA:2.40.30.10 293 391 3.0E-18 T 28-03-2018 A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 SUPERFAMILY SSF52540 10 277 5.22E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 Pfam PF00009 Elongation factor Tu GTP binding domain 13 277 2.6E-46 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 PRINTS PR00315 GTP-binding elongation factor signature 65 73 3.3E-10 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 PRINTS PR00315 GTP-binding elongation factor signature 15 28 3.3E-10 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 PRINTS PR00315 GTP-binding elongation factor signature 85 95 3.3E-10 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS03050 e6f9a94ba4340b69d2816cc929d425ba 529 PRINTS PR00315 GTP-binding elongation factor signature 137 146 3.3E-10 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS01445 7ebf8db69b0cd4565c421db33edd7ea2 326 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 6 320 1.2E-160 T 28-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 A6A12_RS01445 7ebf8db69b0cd4565c421db33edd7ea2 326 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 87 105 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 A6A12_RS01445 7ebf8db69b0cd4565c421db33edd7ea2 326 Gene3D G3DSA:3.20.20.70 4 244 1.0E-40 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS01445 7ebf8db69b0cd4565c421db33edd7ea2 326 SUPERFAMILY SSF51395 6 318 8.55E-73 T 28-03-2018 A6A12_RS01445 7ebf8db69b0cd4565c421db33edd7ea2 326 PIRSF PIRSF006621 1 324 2.4E-75 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A6A12_RS01445 7ebf8db69b0cd4565c421db33edd7ea2 326 Pfam PF01207 Dihydrouridine synthase (Dus) 9 317 8.0E-94 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A6A12_RS01445 7ebf8db69b0cd4565c421db33edd7ea2 326 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 1 322 53.436 T 28-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 A6A12_RS09420 b42f0a2bae1385f65f781028bc2f9263 470 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 362 457 1.9E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09420 b42f0a2bae1385f65f781028bc2f9263 470 Gene3D G3DSA:1.10.287.130 244 313 5.4E-12 T 28-03-2018 A6A12_RS09420 b42f0a2bae1385f65f781028bc2f9263 470 Gene3D G3DSA:3.30.565.10 314 470 9.7E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09420 b42f0a2bae1385f65f781028bc2f9263 470 SUPERFAMILY SSF55874 325 469 1.96E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09420 b42f0a2bae1385f65f781028bc2f9263 470 Gene3D G3DSA:1.20.5.1040 157 201 5.4E-6 T 28-03-2018 A6A12_RS09420 b42f0a2bae1385f65f781028bc2f9263 470 Gene3D G3DSA:1.20.5.1040 7 62 3.0E-6 T 28-03-2018 A6A12_RS09420 b42f0a2bae1385f65f781028bc2f9263 470 Pfam PF00512 His Kinase A (phospho-acceptor) domain 256 318 3.0E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS09420 b42f0a2bae1385f65f781028bc2f9263 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 9.9E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS09420 b42f0a2bae1385f65f781028bc2f9263 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 449 9.9E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS09420 b42f0a2bae1385f65f781028bc2f9263 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 427 9.9E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS09420 b42f0a2bae1385f65f781028bc2f9263 470 Pfam PF08521 Two-component sensor kinase N-terminal 24 177 5.5E-10 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal A6A12_RS09420 b42f0a2bae1385f65f781028bc2f9263 470 SUPERFAMILY SSF47384 237 318 1.12E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS09420 b42f0a2bae1385f65f781028bc2f9263 470 SMART SM00388 254 319 8.0E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS09420 b42f0a2bae1385f65f781028bc2f9263 470 SMART SM00387 362 470 1.6E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS10865 dfd0caa712a0abd0a61ae62fd1b5037e 169 Gene3D G3DSA:3.30.910.20 15 169 3.4E-21 T 28-03-2018 A6A12_RS10865 dfd0caa712a0abd0a61ae62fd1b5037e 169 SMART SM00935 15 169 2.6E-41 T 28-03-2018 IPR005632 Chaperone protein Skp GO:0051082 A6A12_RS10865 dfd0caa712a0abd0a61ae62fd1b5037e 169 SUPERFAMILY SSF111384 26 169 6.93E-31 T 28-03-2018 IPR024930 Skp domain A6A12_RS10865 dfd0caa712a0abd0a61ae62fd1b5037e 169 PIRSF PIRSF002094 1 169 2.8E-40 T 28-03-2018 IPR005632 Chaperone protein Skp GO:0051082 A6A12_RS10865 dfd0caa712a0abd0a61ae62fd1b5037e 169 Pfam PF03938 Outer membrane protein (OmpH-like) 13 168 1.1E-24 T 28-03-2018 IPR005632 Chaperone protein Skp GO:0051082 A6A12_RS08395 d9969b88aa40913954142caba9b7fa02 970 Pfam PF09718 Lambda phage tail tape-measure protein (Tape_meas_lam_C) 721 794 1.9E-20 T 28-03-2018 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal A6A12_RS08395 d9969b88aa40913954142caba9b7fa02 970 Gene3D G3DSA:1.20.1000.10 38 477 5.7E-4 T 28-03-2018 A6A12_RS08395 d9969b88aa40913954142caba9b7fa02 970 Pfam PF06791 Prophage tail length tape measure protein 116 316 1.9E-79 T 28-03-2018 IPR009628 Bacteriophage lambda, GpH, tail tape measure, N-terminal A6A12_RS08395 d9969b88aa40913954142caba9b7fa02 970 TIGRFAM TIGR01541 tape_meas_lam_C: phage tail tape measure protein, lambda family 570 915 3.7E-46 T 28-03-2018 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal A6A12_RS01650 d69a70638d1e107cf607686e45ab3a7d 1473 SMART SM00560 353 489 3.0E-9 T 28-03-2018 IPR006558 LamG-like jellyroll fold A6A12_RS01650 d69a70638d1e107cf607686e45ab3a7d 1473 SUPERFAMILY SSF49899 687 765 3.17E-21 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain A6A12_RS01650 d69a70638d1e107cf607686e45ab3a7d 1473 SUPERFAMILY SSF49899 511 656 3.17E-21 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain A6A12_RS01650 d69a70638d1e107cf607686e45ab3a7d 1473 SUPERFAMILY SSF49899 270 497 5.02E-33 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain A6A12_RS01650 d69a70638d1e107cf607686e45ab3a7d 1473 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 337 491 1.3E-30 T 28-03-2018 A6A12_RS01650 d69a70638d1e107cf607686e45ab3a7d 1473 Pfam PF04519 Polymer-forming cytoskeletal 119 191 2.0E-6 T 28-03-2018 IPR007607 Protein of unknown function DUF583 A6A12_RS01650 d69a70638d1e107cf607686e45ab3a7d 1473 Gene3D G3DSA:2.60.120.200 502 770 4.0E-34 T 28-03-2018 A6A12_RS01650 d69a70638d1e107cf607686e45ab3a7d 1473 Gene3D G3DSA:2.60.120.200 272 499 5.6E-34 T 28-03-2018 A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.2E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.2E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.2E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.2E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.2E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 Gene3D G3DSA:3.40.50.720 1 49 2.4E-11 T 28-03-2018 A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 Gene3D G3DSA:3.40.50.720 50 245 4.6E-66 T 28-03-2018 A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 216 1.5E-4 T 28-03-2018 A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 9.7E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 9.7E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 9.7E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 SUPERFAMILY SSF51735 5 244 1.35E-86 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 243 3.7E-100 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A6A12_RS09685 4e788eb63da900e7fbecad60e6e9065e 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 5.3E-67 T 28-03-2018 A6A12_RS11630 01a6a737500663b73339ef6075e71510 142 Pfam PF00572 Ribosomal protein L13 15 138 3.3E-56 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A6A12_RS11630 01a6a737500663b73339ef6075e71510 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 28-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 A6A12_RS11630 01a6a737500663b73339ef6075e71510 142 SUPERFAMILY SSF52161 1 140 6.02E-60 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A6A12_RS11630 01a6a737500663b73339ef6075e71510 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 4.7E-64 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS11630 01a6a737500663b73339ef6075e71510 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.522 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A6A12_RS11630 01a6a737500663b73339ef6075e71510 142 PIRSF PIRSF002181 1 142 4.9E-52 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A6A12_RS11630 01a6a737500663b73339ef6075e71510 142 Gene3D G3DSA:3.90.1180.10 1 142 2.9E-62 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A6A12_RS09470 59450c3591b87ef9679ff4fd180d312c 688 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 275 458 5.2E-21 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS09470 59450c3591b87ef9679ff4fd180d312c 688 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 57 239 5.1E-19 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS09470 59450c3591b87ef9679ff4fd180d312c 688 Gene3D G3DSA:3.40.190.10 137 200 6.6E-4 T 28-03-2018 A6A12_RS09470 59450c3591b87ef9679ff4fd180d312c 688 Gene3D G3DSA:3.30.70.270 520 682 5.4E-36 T 28-03-2018 A6A12_RS09470 59450c3591b87ef9679ff4fd180d312c 688 Gene3D G3DSA:3.40.190.10 386 486 8.2E-5 T 28-03-2018 A6A12_RS09470 59450c3591b87ef9679ff4fd180d312c 688 SMART SM00267 514 675 2.4E-20 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS09470 59450c3591b87ef9679ff4fd180d312c 688 SUPERFAMILY SSF53850 275 480 4.8E-24 T 28-03-2018 A6A12_RS09470 59450c3591b87ef9679ff4fd180d312c 688 SMART SM00062 42 243 2.4E-7 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS09470 59450c3591b87ef9679ff4fd180d312c 688 SMART SM00062 262 483 0.0036 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS09470 59450c3591b87ef9679ff4fd180d312c 688 SUPERFAMILY SSF53850 35 239 6.73E-22 T 28-03-2018 A6A12_RS09470 59450c3591b87ef9679ff4fd180d312c 688 SUPERFAMILY SSF55073 530 671 5.18E-30 T 28-03-2018 IPR029787 Nucleotide cyclase A6A12_RS09470 59450c3591b87ef9679ff4fd180d312c 688 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 521 671 7.1E-29 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS09470 59450c3591b87ef9679ff4fd180d312c 688 Pfam PF00990 Diguanylate cyclase, GGDEF domain 526 670 9.0E-28 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS09470 59450c3591b87ef9679ff4fd180d312c 688 Gene3D G3DSA:3.40.190.10 56 136 1.0E-7 T 28-03-2018 A6A12_RS09470 59450c3591b87ef9679ff4fd180d312c 688 Gene3D G3DSA:3.40.190.10 258 385 4.6E-14 T 28-03-2018 A6A12_RS07490 55db8ea88f0a77290fd5deb67f128312 180 Gene3D G3DSA:3.30.1380.10 53 180 3.4E-25 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A6A12_RS07490 55db8ea88f0a77290fd5deb67f128312 180 Pfam PF05951 Bacterial protein of unknown function (DUF882) 31 179 1.2E-67 T 28-03-2018 IPR010275 Protein of unknown function DUF882 A6A12_RS07490 55db8ea88f0a77290fd5deb67f128312 180 SUPERFAMILY SSF55166 62 180 1.23E-34 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A6A12_RS07490 55db8ea88f0a77290fd5deb67f128312 180 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 28 1.5E-4 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal A6A12_RS14015 fd986f0ac3e10465e1b3d53eb1b644c4 494 Gene3D G3DSA:1.10.1040.10 210 490 1.9E-79 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A6A12_RS14015 fd986f0ac3e10465e1b3d53eb1b644c4 494 Gene3D G3DSA:3.40.50.720 58 208 2.0E-49 T 28-03-2018 A6A12_RS14015 fd986f0ac3e10465e1b3d53eb1b644c4 494 Gene3D G3DSA:3.40.50.720 1 42 3.2E-4 T 28-03-2018 A6A12_RS14015 fd986f0ac3e10465e1b3d53eb1b644c4 494 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 352 485 6.4E-16 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A6A12_RS14015 fd986f0ac3e10465e1b3d53eb1b644c4 494 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 210 341 8.9E-26 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A6A12_RS14015 fd986f0ac3e10465e1b3d53eb1b644c4 494 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 35 204 3.6E-60 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A6A12_RS14015 fd986f0ac3e10465e1b3d53eb1b644c4 494 SUPERFAMILY SSF51735 27 209 7.58E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS14015 fd986f0ac3e10465e1b3d53eb1b644c4 494 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 22 488 37.214 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A6A12_RS14015 fd986f0ac3e10465e1b3d53eb1b644c4 494 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 35 367 7.9E-125 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 A6A12_RS14015 fd986f0ac3e10465e1b3d53eb1b644c4 494 SUPERFAMILY SSF48179 348 487 3.06E-41 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A6A12_RS14015 fd986f0ac3e10465e1b3d53eb1b644c4 494 SUPERFAMILY SSF48179 210 341 3.23E-39 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A6A12_RS11175 64264525a1f4f19fdb0fb52246eb64bd 1205 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 12 1186 0.0 T 28-03-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 A6A12_RS11175 64264525a1f4f19fdb0fb52246eb64bd 1205 Pfam PF00580 UvrD/REP helicase N-terminal domain 19 438 8.1E-59 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A6A12_RS11175 64264525a1f4f19fdb0fb52246eb64bd 1205 Gene3D G3DSA:3.40.50.300 599 893 1.3E-28 T 28-03-2018 A6A12_RS11175 64264525a1f4f19fdb0fb52246eb64bd 1205 Gene3D G3DSA:3.40.50.300 445 598 7.2E-18 T 28-03-2018 A6A12_RS11175 64264525a1f4f19fdb0fb52246eb64bd 1205 SUPERFAMILY SSF52540 802 831 9.64E-109 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11175 64264525a1f4f19fdb0fb52246eb64bd 1205 SUPERFAMILY SSF52540 123 207 9.64E-109 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11175 64264525a1f4f19fdb0fb52246eb64bd 1205 SUPERFAMILY SSF52540 326 772 9.64E-109 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11175 64264525a1f4f19fdb0fb52246eb64bd 1205 SUPERFAMILY SSF52540 18 85 9.64E-109 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11175 64264525a1f4f19fdb0fb52246eb64bd 1205 Gene3D G3DSA:3.90.320.10 895 1194 2.3E-81 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 A6A12_RS11175 64264525a1f4f19fdb0fb52246eb64bd 1205 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 10 1187 22.873 T 28-03-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 A6A12_RS11175 64264525a1f4f19fdb0fb52246eb64bd 1205 SUPERFAMILY SSF52980 907 1188 2.52E-85 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A6A12_RS11175 64264525a1f4f19fdb0fb52246eb64bd 1205 Pfam PF12705 PD-(D/E)XK nuclease superfamily 962 1160 3.4E-7 T 28-03-2018 A6A12_RS11175 64264525a1f4f19fdb0fb52246eb64bd 1205 Gene3D G3DSA:3.40.50.300 14 444 6.9E-51 T 28-03-2018 A6A12_RS11175 64264525a1f4f19fdb0fb52246eb64bd 1205 Pfam PF13361 UvrD-like helicase C-terminal domain 442 816 1.4E-17 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A6A12_RS02150 3d43515962b703ce1fcfa28040fa5ffe 375 SUPERFAMILY SSF47413 4 69 5.63E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS02150 3d43515962b703ce1fcfa28040fa5ffe 375 Pfam PF01381 Helix-turn-helix 7 62 9.9E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A6A12_RS02150 3d43515962b703ce1fcfa28040fa5ffe 375 Gene3D G3DSA:1.10.260.40 1 71 6.4E-12 T 28-03-2018 A6A12_RS02150 3d43515962b703ce1fcfa28040fa5ffe 375 Pfam PF06114 IrrE N-terminal-like domain 154 266 4.2E-18 T 28-03-2018 IPR010359 IrrE N-terminal-like domain A6A12_RS02150 3d43515962b703ce1fcfa28040fa5ffe 375 SMART SM00530 6 63 7.9E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 428 706 1.3E-95 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 Gene3D G3DSA:3.20.20.60 416 738 4.8E-85 T 28-03-2018 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 SUPERFAMILY SSF47831 198 311 5.23E-27 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 Gene3D G3DSA:3.30.450.40 1 161 1.6E-29 T 28-03-2018 IPR029016 GAF domain-like A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 172 727 1.2E-133 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 SUPERFAMILY SSF55781 2 159 2.62E-33 T 28-03-2018 IPR029016 GAF domain-like A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 SMART SM00065 17 163 3.7E-22 T 28-03-2018 IPR003018 GAF domain GO:0005515 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 Pfam PF00391 PEP-utilising enzyme, mobile domain 319 391 4.3E-15 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 Pfam PF05524 PEP-utilising enzyme, N-terminal 173 294 3.9E-23 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 SUPERFAMILY SSF52009 293 411 1.31E-25 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 351 362 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 SUPERFAMILY SSF51621 421 714 8.64E-97 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 Pfam PF01590 GAF domain 17 153 1.8E-14 T 28-03-2018 IPR003018 GAF domain GO:0005515 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 Gene3D G3DSA:1.10.274.10 196 310 3.9E-26 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 612 630 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 612 627 4.0E-22 T 28-03-2018 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 459 478 4.0E-22 T 28-03-2018 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 665 677 4.0E-22 T 28-03-2018 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 629 644 4.0E-22 T 28-03-2018 A6A12_RS03105 d14190a21ff607e3212ad9412d104706 748 Gene3D G3DSA:3.50.30.10 311 410 9.1E-19 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A6A12_RS02735 1c7110b142a90d0f62d4592214c61b24 822 Pfam PF00271 Helicase conserved C-terminal domain 208 326 1.0E-12 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS02735 1c7110b142a90d0f62d4592214c61b24 822 SMART SM00847 387 477 8.8E-7 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 A6A12_RS02735 1c7110b142a90d0f62d4592214c61b24 822 Pfam PF00270 DEAD/DEAH box helicase 7 160 1.2E-7 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A6A12_RS02735 1c7110b142a90d0f62d4592214c61b24 822 PIRSF PIRSF005496 1 821 0.0 T 28-03-2018 A6A12_RS02735 1c7110b142a90d0f62d4592214c61b24 822 Gene3D G3DSA:3.40.50.300 180 347 1.1E-43 T 28-03-2018 A6A12_RS02735 1c7110b142a90d0f62d4592214c61b24 822 SUPERFAMILY SSF52540 19 471 6.38E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS02735 1c7110b142a90d0f62d4592214c61b24 822 SMART SM00490 226 327 2.4E-14 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS02735 1c7110b142a90d0f62d4592214c61b24 822 SMART SM00487 4 186 2.1E-8 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS02735 1c7110b142a90d0f62d4592214c61b24 822 Pfam PF08482 ATP-dependent helicase C-terminal 675 807 5.2E-52 T 28-03-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal A6A12_RS02735 1c7110b142a90d0f62d4592214c61b24 822 Pfam PF04408 Helicase associated domain (HA2) 388 476 1.6E-8 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 A6A12_RS02735 1c7110b142a90d0f62d4592214c61b24 822 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 4 819 0.0 T 28-03-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 A6A12_RS02735 1c7110b142a90d0f62d4592214c61b24 822 Gene3D G3DSA:3.40.50.300 3 162 8.7E-20 T 28-03-2018 A6A12_RS06005 8f51a74d6c42556599550fd4208fcad4 379 PIRSF PIRSF029172 1 379 2.6E-172 T 28-03-2018 IPR027020 Protein ynjB A6A12_RS06005 8f51a74d6c42556599550fd4208fcad4 379 Gene3D G3DSA:3.40.190.10 165 328 1.4E-23 T 28-03-2018 A6A12_RS06005 8f51a74d6c42556599550fd4208fcad4 379 SUPERFAMILY SSF53850 31 377 8.26E-45 T 28-03-2018 A6A12_RS06005 8f51a74d6c42556599550fd4208fcad4 379 Pfam PF13416 Bacterial extracellular solute-binding protein 55 328 3.7E-28 T 28-03-2018 A6A12_RS06005 8f51a74d6c42556599550fd4208fcad4 379 Gene3D G3DSA:3.40.190.10 27 164 0.0013 T 28-03-2018 A6A12_RS12635 82fa67f675fad356600dbe0e48cc5c3b 296 Pfam PF03466 LysR substrate binding domain 90 293 5.6E-33 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS12635 82fa67f675fad356600dbe0e48cc5c3b 296 SUPERFAMILY SSF46785 4 112 6.53E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS12635 82fa67f675fad356600dbe0e48cc5c3b 296 Gene3D G3DSA:3.40.190.10 187 264 0.0045 T 28-03-2018 A6A12_RS12635 82fa67f675fad356600dbe0e48cc5c3b 296 SUPERFAMILY SSF53850 90 295 1.99E-35 T 28-03-2018 A6A12_RS12635 82fa67f675fad356600dbe0e48cc5c3b 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.4E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS12635 82fa67f675fad356600dbe0e48cc5c3b 296 Gene3D G3DSA:1.10.10.10 3 87 3.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS12635 82fa67f675fad356600dbe0e48cc5c3b 296 Gene3D G3DSA:3.40.190.10 88 186 7.2E-15 T 28-03-2018 A6A12_RS14220 231f6e4e955cdd90dff14738a07b1a2a 313 SUPERFAMILY SSF46785 7 87 1.84E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS14220 231f6e4e955cdd90dff14738a07b1a2a 313 Gene3D G3DSA:3.40.190.10 192 281 1.8E-15 T 28-03-2018 A6A12_RS14220 231f6e4e955cdd90dff14738a07b1a2a 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 7.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS14220 231f6e4e955cdd90dff14738a07b1a2a 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 7.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS14220 231f6e4e955cdd90dff14738a07b1a2a 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 7.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS14220 231f6e4e955cdd90dff14738a07b1a2a 313 Gene3D G3DSA:3.40.190.10 97 191 5.8E-9 T 28-03-2018 A6A12_RS14220 231f6e4e955cdd90dff14738a07b1a2a 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 8.5E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS14220 231f6e4e955cdd90dff14738a07b1a2a 313 Pfam PF03466 LysR substrate binding domain 96 307 1.2E-29 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS14220 231f6e4e955cdd90dff14738a07b1a2a 313 SUPERFAMILY SSF53850 92 306 1.14E-46 T 28-03-2018 A6A12_RS14220 231f6e4e955cdd90dff14738a07b1a2a 313 Gene3D G3DSA:1.10.10.10 1 91 8.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS08200 bcefffae354ba50029f99dec24532968 188 TIGRFAM TIGR02178 yeiP: elongation factor P-like protein YeiP 3 188 1.7E-94 T 28-03-2018 IPR011897 Translation elongation factor P-like, YeiP A6A12_RS08200 bcefffae354ba50029f99dec24532968 188 ProSitePatterns PS01275 Elongation factor P signature. 153 172 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site A6A12_RS08200 bcefffae354ba50029f99dec24532968 188 PIRSF PIRSF005901 1 188 2.5E-59 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP A6A12_RS08200 bcefffae354ba50029f99dec24532968 188 SMART SM00841 132 187 3.8E-28 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A6A12_RS08200 bcefffae354ba50029f99dec24532968 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 70 123 4.0E-13 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A6A12_RS08200 bcefffae354ba50029f99dec24532968 188 Pfam PF09285 Elongation factor P, C-terminal 132 187 9.3E-21 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 A6A12_RS08200 bcefffae354ba50029f99dec24532968 188 SMART SM01185 69 124 3.0E-14 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 A6A12_RS08200 bcefffae354ba50029f99dec24532968 188 Gene3D G3DSA:2.40.50.140 67 125 4.2E-15 T 28-03-2018 A6A12_RS08200 bcefffae354ba50029f99dec24532968 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 61 3.6E-14 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like A6A12_RS08200 bcefffae354ba50029f99dec24532968 188 SUPERFAMILY SSF50249 67 129 1.63E-10 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS08200 bcefffae354ba50029f99dec24532968 188 SUPERFAMILY SSF50104 1 65 7.82E-10 T 28-03-2018 IPR008991 Translation protein SH3-like domain A6A12_RS08200 bcefffae354ba50029f99dec24532968 188 SUPERFAMILY SSF50249 132 188 2.4E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS08200 bcefffae354ba50029f99dec24532968 188 Gene3D G3DSA:2.40.50.140 132 187 3.3E-22 T 28-03-2018 A6A12_RS08200 bcefffae354ba50029f99dec24532968 188 Gene3D G3DSA:2.30.30.30 2 63 2.2E-11 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 A6A12_RS08200 bcefffae354ba50029f99dec24532968 188 Hamap MF_00646 Elongation factor P-like protein [yeiP]. 2 188 41.765 T 28-03-2018 IPR011897 Translation elongation factor P-like, YeiP A6A12_RS12185 c6b437d5048e2ffdf08424e5d949e639 451 SMART SM00116 212 258 0.029 T 28-03-2018 IPR000644 CBS domain A6A12_RS12185 c6b437d5048e2ffdf08424e5d949e639 451 SMART SM00116 146 199 41.0 T 28-03-2018 IPR000644 CBS domain A6A12_RS12185 c6b437d5048e2ffdf08424e5d949e639 451 Gene3D G3DSA:3.10.580.10 135 262 1.8E-18 T 28-03-2018 A6A12_RS12185 c6b437d5048e2ffdf08424e5d949e639 451 SMART SM00924 36 139 4.6E-37 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain A6A12_RS12185 c6b437d5048e2ffdf08424e5d949e639 451 SUPERFAMILY SSF158791 13 136 2.22E-30 T 28-03-2018 A6A12_RS12185 c6b437d5048e2ffdf08424e5d949e639 451 SUPERFAMILY SSF54631 138 278 1.77E-28 T 28-03-2018 A6A12_RS12185 c6b437d5048e2ffdf08424e5d949e639 451 Gene3D G3DSA:1.10.357.20 279 451 2.1E-32 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A6A12_RS12185 c6b437d5048e2ffdf08424e5d949e639 451 Pfam PF01769 Divalent cation transporter 323 444 2.2E-23 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A6A12_RS12185 c6b437d5048e2ffdf08424e5d949e639 451 SUPERFAMILY SSF161093 280 450 3.66E-44 T 28-03-2018 A6A12_RS12185 c6b437d5048e2ffdf08424e5d949e639 451 TIGRFAM TIGR00400 mgtE: magnesium transporter 17 450 3.1E-89 T 28-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 A6A12_RS12185 c6b437d5048e2ffdf08424e5d949e639 451 Gene3D G3DSA:1.25.60.10 5 134 9.4E-23 T 28-03-2018 A6A12_RS12185 c6b437d5048e2ffdf08424e5d949e639 451 Pfam PF00571 CBS domain 217 257 2.5E-4 T 28-03-2018 IPR000644 CBS domain A6A12_RS12185 c6b437d5048e2ffdf08424e5d949e639 451 Pfam PF00571 CBS domain 140 196 6.1E-5 T 28-03-2018 IPR000644 CBS domain A6A12_RS12185 c6b437d5048e2ffdf08424e5d949e639 451 Pfam PF03448 MgtE intracellular N domain 36 137 1.6E-26 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain A6A12_RS12290 e02d5e221ba9aac19cee1311228caf68 299 TIGRFAM TIGR03899 TIGR03899: TIGR03899 family protein 37 286 9.4E-106 T 28-03-2018 IPR021254 Protein of unknown function DUF2806 A6A12_RS12290 e02d5e221ba9aac19cee1311228caf68 299 Pfam PF10987 Protein of unknown function (DUF2806) 58 276 1.2E-85 T 28-03-2018 IPR021254 Protein of unknown function DUF2806 A6A12_RS03830 9c04d9ecd8418fdfbc231340d2d0f70f 591 Gene3D G3DSA:3.90.220.20 5 191 2.5E-30 T 28-03-2018 A6A12_RS03830 9c04d9ecd8418fdfbc231340d2d0f70f 591 Gene3D G3DSA:3.90.220.20 192 441 4.8E-28 T 28-03-2018 A6A12_RS03830 9c04d9ecd8418fdfbc231340d2d0f70f 591 Pfam PF01420 Type I restriction modification DNA specificity domain 281 452 6.2E-15 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A6A12_RS03830 9c04d9ecd8418fdfbc231340d2d0f70f 591 Pfam PF01420 Type I restriction modification DNA specificity domain 26 184 1.0E-19 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A6A12_RS03830 9c04d9ecd8418fdfbc231340d2d0f70f 591 SUPERFAMILY SSF116734 269 486 8.83E-36 T 28-03-2018 A6A12_RS03830 9c04d9ecd8418fdfbc231340d2d0f70f 591 SUPERFAMILY SSF116734 25 219 2.78E-35 T 28-03-2018 A6A12_RS03830 9c04d9ecd8418fdfbc231340d2d0f70f 591 Gene3D G3DSA:1.10.287.1120 442 574 1.0E-8 T 28-03-2018 A6A12_RS12590 2884aa5d303d0fec4f66a8bb948f3b58 210 Pfam PF00027 Cyclic nucleotide-binding domain 23 109 7.0E-23 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A6A12_RS12590 2884aa5d303d0fec4f66a8bb948f3b58 210 SUPERFAMILY SSF46785 139 207 3.88E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS12590 2884aa5d303d0fec4f66a8bb948f3b58 210 Gene3D G3DSA:1.10.10.10 145 210 7.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS12590 2884aa5d303d0fec4f66a8bb948f3b58 210 SMART SM00419 160 208 4.2E-17 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A6A12_RS12590 2884aa5d303d0fec4f66a8bb948f3b58 210 Gene3D G3DSA:2.60.120.10 4 144 3.4E-33 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS12590 2884aa5d303d0fec4f66a8bb948f3b58 210 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 182 197 5.7E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A6A12_RS12590 2884aa5d303d0fec4f66a8bb948f3b58 210 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 166 182 5.7E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A6A12_RS12590 2884aa5d303d0fec4f66a8bb948f3b58 210 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 71 89 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site A6A12_RS12590 2884aa5d303d0fec4f66a8bb948f3b58 210 ProSitePatterns PS00042 Crp-type HTH domain signature. 168 191 - T 28-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 A6A12_RS12590 2884aa5d303d0fec4f66a8bb948f3b58 210 Pfam PF00325 Bacterial regulatory proteins, crp family 166 197 8.8E-16 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A6A12_RS12590 2884aa5d303d0fec4f66a8bb948f3b58 210 SUPERFAMILY SSF51206 8 137 1.57E-34 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like A6A12_RS12590 2884aa5d303d0fec4f66a8bb948f3b58 210 SMART SM00100 2 122 1.2E-26 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A6A12_RS12590 2884aa5d303d0fec4f66a8bb948f3b58 210 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 30 46 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 Gene3D G3DSA:2.40.37.10 255 407 8.5E-50 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 TIGRFAM TIGR00492 alr: alanine racemase 43 406 2.7E-67 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 Gene3D G3DSA:3.20.20.10 42 254 2.4E-33 T 28-03-2018 IPR029066 PLP-binding barrel A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 Pfam PF00842 Alanine racemase, C-terminal domain 279 405 4.0E-31 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 PRINTS PR00992 Alanine racemase signature 102 120 6.1E-32 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 PRINTS PR00992 Alanine racemase signature 164 176 6.1E-32 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 PRINTS PR00992 Alanine racemase signature 332 349 6.1E-32 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 PRINTS PR00992 Alanine racemase signature 200 211 6.1E-32 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 PRINTS PR00992 Alanine racemase signature 311 326 6.1E-32 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 PRINTS PR00992 Alanine racemase signature 66 82 6.1E-32 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 PRINTS PR00992 Alanine racemase signature 243 270 6.1E-32 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 Pfam PF01168 Alanine racemase, N-terminal domain 47 270 9.8E-50 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 SUPERFAMILY SSF51419 47 281 1.83E-46 T 28-03-2018 IPR029066 PLP-binding barrel A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 SUPERFAMILY SSF50621 271 406 1.53E-38 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 71 81 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 Hamap MF_01201 Alanine racemase. 40 406 25.577 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS07295 80b5cd939de593bbd83d7dc4642ea86e 407 SMART SM01005 278 406 7.7E-45 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS11145 4e9d6364499550d29b034989a41ee019 269 Gene3D G3DSA:3.40.50.720 6 269 1.9E-52 T 28-03-2018 A6A12_RS11145 4e9d6364499550d29b034989a41ee019 269 SUPERFAMILY SSF69572 9 268 4.58E-62 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A6A12_RS11145 4e9d6364499550d29b034989a41ee019 269 Pfam PF00899 ThiF family 23 263 2.7E-36 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A6A12_RS10860 84a549d0cfb8d42751a635ba945dc846 343 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 24 88 4.5E-20 T 28-03-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 A6A12_RS10860 84a549d0cfb8d42751a635ba945dc846 343 Gene3D G3DSA:2.160.10.10 134 309 3.1E-43 T 28-03-2018 A6A12_RS10860 84a549d0cfb8d42751a635ba945dc846 343 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 106 134 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A6A12_RS10860 84a549d0cfb8d42751a635ba945dc846 343 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 201 233 0.15 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS10860 84a549d0cfb8d42751a635ba945dc846 343 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 5 326 34.955 T 28-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 A6A12_RS10860 84a549d0cfb8d42751a635ba945dc846 343 SUPERFAMILY SSF51161 32 316 1.36E-83 T 28-03-2018 IPR011004 Trimeric LpxA-like A6A12_RS10860 84a549d0cfb8d42751a635ba945dc846 343 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 8 329 6.7E-119 T 28-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 A6A12_RS10860 84a549d0cfb8d42751a635ba945dc846 343 Gene3D G3DSA:2.160.10.10 60 133 5.8E-10 T 28-03-2018 A6A12_RS10860 84a549d0cfb8d42751a635ba945dc846 343 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 110 144 8.7E-10 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS10860 84a549d0cfb8d42751a635ba945dc846 343 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 145 179 1.4E-7 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS13110 c29c277774ef8843d8da91a6bdb93118 331 PIRSF PIRSF006621 9 330 2.3E-101 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A6A12_RS13110 c29c277774ef8843d8da91a6bdb93118 331 Gene3D G3DSA:1.10.1200.80 261 331 1.5E-20 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 A6A12_RS13110 c29c277774ef8843d8da91a6bdb93118 331 SUPERFAMILY SSF51395 19 328 2.2E-89 T 28-03-2018 A6A12_RS13110 c29c277774ef8843d8da91a6bdb93118 331 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 12 329 2.3E-131 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 A6A12_RS13110 c29c277774ef8843d8da91a6bdb93118 331 Gene3D G3DSA:3.20.20.70 17 249 1.1E-56 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS13110 c29c277774ef8843d8da91a6bdb93118 331 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 10 330 49.738 T 28-03-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 A6A12_RS13110 c29c277774ef8843d8da91a6bdb93118 331 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 103 121 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 A6A12_RS13110 c29c277774ef8843d8da91a6bdb93118 331 Pfam PF01207 Dihydrouridine synthase (Dus) 22 314 1.7E-109 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 A6A12_RS04480 06c3048c9e0ac9ea2bddb793eb6f989d 130 Pfam PF00376 MerR family regulatory protein 8 30 9.3E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A6A12_RS04480 06c3048c9e0ac9ea2bddb793eb6f989d 130 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 5 118 4.4E-47 T 28-03-2018 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 A6A12_RS04480 06c3048c9e0ac9ea2bddb793eb6f989d 130 SMART SM00422 5 61 9.6E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 A6A12_RS04480 06c3048c9e0ac9ea2bddb793eb6f989d 130 Pfam PF09278 MerR, DNA binding 37 98 2.3E-15 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding A6A12_RS04480 06c3048c9e0ac9ea2bddb793eb6f989d 130 Gene3D G3DSA:1.10.1660.10 5 47 1.4E-13 T 28-03-2018 A6A12_RS04480 06c3048c9e0ac9ea2bddb793eb6f989d 130 SUPERFAMILY SSF46955 6 117 6.59E-27 T 28-03-2018 IPR009061 Putative DNA-binding domain A6A12_RS04480 06c3048c9e0ac9ea2bddb793eb6f989d 130 Gene3D G3DSA:1.10.1660.10 48 128 8.0E-15 T 28-03-2018 A6A12_RS01655 e98755240404e82390ab912b8a163026 347 Gene3D G3DSA:3.90.640.10 198 256 7.3E-28 T 28-03-2018 A6A12_RS01655 e98755240404e82390ab912b8a163026 347 Gene3D G3DSA:3.30.420.40 164 197 4.4E-4 T 28-03-2018 A6A12_RS01655 e98755240404e82390ab912b8a163026 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 339 2.9E-164 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A6A12_RS01655 e98755240404e82390ab912b8a163026 347 SUPERFAMILY SSF53067 9 152 6.31E-38 T 28-03-2018 A6A12_RS01655 e98755240404e82390ab912b8a163026 347 SUPERFAMILY SSF53067 154 340 1.71E-51 T 28-03-2018 A6A12_RS01655 e98755240404e82390ab912b8a163026 347 Pfam PF06723 MreB/Mbl protein 11 338 7.0E-148 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A6A12_RS01655 e98755240404e82390ab912b8a163026 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 52 70 1.6E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A6A12_RS01655 e98755240404e82390ab912b8a163026 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 136 155 1.6E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A6A12_RS01655 e98755240404e82390ab912b8a163026 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 191 211 1.6E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A6A12_RS01655 e98755240404e82390ab912b8a163026 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 304 330 1.6E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A6A12_RS01655 e98755240404e82390ab912b8a163026 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 72 95 1.6E-63 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 A6A12_RS01655 e98755240404e82390ab912b8a163026 347 Gene3D G3DSA:3.30.420.40 257 321 3.4E-9 T 28-03-2018 A6A12_RS01655 e98755240404e82390ab912b8a163026 347 Gene3D G3DSA:3.30.420.40 8 163 3.3E-41 T 28-03-2018 A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 SUPERFAMILY SSF55785 6 115 1.39E-10 T 28-03-2018 IPR000014 PAS domain A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 SUPERFAMILY SSF55073 258 412 1.41E-46 T 28-03-2018 IPR029787 Nucleotide cyclase A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 SMART SM00091 131 198 0.47 T 28-03-2018 IPR000014 PAS domain A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 SMART SM00091 8 74 7.5E-4 T 28-03-2018 IPR000014 PAS domain A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 Gene3D G3DSA:3.30.70.270 251 417 4.4E-54 T 28-03-2018 A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 SUPERFAMILY SSF141868 427 674 7.85E-85 T 28-03-2018 IPR001633 EAL domain A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 254 407 5.0E-37 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 SMART SM00267 242 410 3.8E-56 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 Pfam PF08448 PAS fold 15 119 1.4E-7 T 28-03-2018 IPR013656 PAS fold-4 A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 Gene3D G3DSA:3.30.450.20 10 124 2.6E-12 T 28-03-2018 A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 SUPERFAMILY SSF55785 115 199 3.81E-7 T 28-03-2018 IPR000014 PAS domain A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 SMART SM00052 420 666 3.2E-106 T 28-03-2018 IPR001633 EAL domain A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 Gene3D G3DSA:3.20.20.450 418 680 2.6E-95 T 28-03-2018 IPR001633 EAL domain A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 Pfam PF13188 PAS domain 132 179 5.1E-6 T 28-03-2018 IPR000014 PAS domain A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 Pfam PF00990 Diguanylate cyclase, GGDEF domain 254 406 2.7E-42 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 8 120 2.0E-9 T 28-03-2018 IPR000014 PAS domain A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 Gene3D G3DSA:3.30.450.20 125 250 5.0E-9 T 28-03-2018 A6A12_RS03020 1af2a8fa54cbe2c119789853083fef7f 682 Pfam PF00563 EAL domain 427 661 7.5E-72 T 28-03-2018 IPR001633 EAL domain A6A12_RS08285 bf7d98b59edb02dbfae4e5fd047f7042 760 SUPERFAMILY SSF47203 301 453 6.77E-21 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A6A12_RS08285 bf7d98b59edb02dbfae4e5fd047f7042 760 Gene3D G3DSA:1.10.540.10 17 176 1.0E-27 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A6A12_RS08285 bf7d98b59edb02dbfae4e5fd047f7042 760 Gene3D G3DSA:1.20.140.10 301 449 6.0E-17 T 28-03-2018 A6A12_RS08285 bf7d98b59edb02dbfae4e5fd047f7042 760 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 301 446 4.9E-9 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A6A12_RS08285 bf7d98b59edb02dbfae4e5fd047f7042 760 Pfam PF09317 Domain of unknown function (DUF1974) 455 739 7.3E-113 T 28-03-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 A6A12_RS08285 bf7d98b59edb02dbfae4e5fd047f7042 760 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 178 277 3.6E-9 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 A6A12_RS08285 bf7d98b59edb02dbfae4e5fd047f7042 760 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 66 173 2.6E-13 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A6A12_RS08285 bf7d98b59edb02dbfae4e5fd047f7042 760 SUPERFAMILY SSF56645 61 296 6.54E-44 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A6A12_RS08285 bf7d98b59edb02dbfae4e5fd047f7042 760 Gene3D G3DSA:2.40.110.10 177 299 9.5E-18 T 28-03-2018 A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 SUPERFAMILY SSF116726 148 226 1.57E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 Gene3D G3DSA:3.30.70.1450 141 232 4.1E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 Gene3D G3DSA:3.40.50.720 233 366 1.5E-24 T 28-03-2018 A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 Gene3D G3DSA:3.30.70.1450 367 458 2.3E-14 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 SUPERFAMILY SSF116726 390 437 7.59E-7 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 SUPERFAMILY SSF51735 1 151 1.38E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 Pfam PF02254 TrkA-N domain 3 115 5.0E-30 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 Pfam PF02254 TrkA-N domain 235 350 1.0E-24 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 Gene3D G3DSA:3.40.50.720 1 140 5.3E-26 T 28-03-2018 A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 Pfam PF02080 TrkA-C domain 156 225 4.2E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 Pfam PF02080 TrkA-C domain 391 449 6.4E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 SUPERFAMILY SSF51735 232 376 4.9E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 6.4E-34 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 6.4E-34 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 6.4E-34 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 6.4E-34 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A6A12_RS00250 a47ba2cf6629b5ea45c03e6575a886db 458 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 6.4E-34 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A6A12_RS08220 de8a89ba7ab070ba51cb21de552fa5df 404 Pfam PF01979 Amidohydrolase family 61 377 1.9E-15 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A6A12_RS08220 de8a89ba7ab070ba51cb21de552fa5df 404 TIGRFAM TIGR01224 hutI: imidazolonepropionase 25 400 6.3E-151 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A6A12_RS08220 de8a89ba7ab070ba51cb21de552fa5df 404 SUPERFAMILY SSF51556 63 362 4.44E-79 T 28-03-2018 IPR032466 Metal-dependent hydrolase A6A12_RS08220 de8a89ba7ab070ba51cb21de552fa5df 404 SUPERFAMILY SSF51338 1 63 3.28E-24 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A6A12_RS08220 de8a89ba7ab070ba51cb21de552fa5df 404 SUPERFAMILY SSF51338 364 402 3.28E-24 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A6A12_RS08220 de8a89ba7ab070ba51cb21de552fa5df 404 Hamap MF_00372 Imidazolonepropionase [hutI]. 2 402 40.244 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A6A12_RS08220 de8a89ba7ab070ba51cb21de552fa5df 404 Gene3D G3DSA:2.30.40.10 1 76 7.4E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A6A12_RS08220 de8a89ba7ab070ba51cb21de552fa5df 404 Gene3D G3DSA:3.20.20.140 77 362 2.3E-48 T 28-03-2018 A6A12_RS13100 8195f9f7e359f217d9c3e0dc7d6e5f55 448 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 446 3.5E-243 T 28-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 A6A12_RS13100 8195f9f7e359f217d9c3e0dc7d6e5f55 448 SUPERFAMILY SSF51246 331 444 8.37E-43 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A6A12_RS13100 8195f9f7e359f217d9c3e0dc7d6e5f55 448 Gene3D G3DSA:3.30.470.20 211 444 5.2E-99 T 28-03-2018 A6A12_RS13100 8195f9f7e359f217d9c3e0dc7d6e5f55 448 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A6A12_RS13100 8195f9f7e359f217d9c3e0dc7d6e5f55 448 SMART SM00878 336 441 7.2E-64 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A6A12_RS13100 8195f9f7e359f217d9c3e0dc7d6e5f55 448 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 1.1E-82 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A6A12_RS13100 8195f9f7e359f217d9c3e0dc7d6e5f55 448 SUPERFAMILY SSF56059 83 348 5.66E-70 T 28-03-2018 A6A12_RS13100 8195f9f7e359f217d9c3e0dc7d6e5f55 448 Gene3D G3DSA:3.40.50.20 1 123 1.5E-49 T 28-03-2018 A6A12_RS13100 8195f9f7e359f217d9c3e0dc7d6e5f55 448 Gene3D G3DSA:3.30.1490.20 124 210 1.3E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A6A12_RS13100 8195f9f7e359f217d9c3e0dc7d6e5f55 448 SUPERFAMILY SSF52440 1 113 1.65E-45 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A6A12_RS13100 8195f9f7e359f217d9c3e0dc7d6e5f55 448 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 A6A12_RS13100 8195f9f7e359f217d9c3e0dc7d6e5f55 448 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 8.9E-38 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A6A12_RS13100 8195f9f7e359f217d9c3e0dc7d6e5f55 448 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 7.8E-43 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A6A12_RS10635 61295abf931185a4e0b154f185c39fd7 434 Pfam PF07559 Flagellar basal body protein FlaE 181 314 1.7E-21 T 28-03-2018 IPR011491 Flagellar hook protein FlgE A6A12_RS10635 61295abf931185a4e0b154f185c39fd7 434 SUPERFAMILY SSF117143 78 395 4.45E-68 T 28-03-2018 A6A12_RS10635 61295abf931185a4e0b154f185c39fd7 434 Pfam PF00460 Flagella basal body rod protein 3 32 1.1E-9 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A6A12_RS10635 61295abf931185a4e0b154f185c39fd7 434 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 355 433 3.3E-15 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A6A12_RS10635 61295abf931185a4e0b154f185c39fd7 434 Gene3D G3DSA:2.60.98.20 154 316 1.4E-28 T 28-03-2018 IPR011491 Flagellar hook protein FlgE A6A12_RS10635 61295abf931185a4e0b154f185c39fd7 434 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 2 416 6.7E-91 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G A6A12_RS10635 61295abf931185a4e0b154f185c39fd7 434 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 8 28 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site A6A12_RS12045 2e2b8a252e34ede2073a8be908d020d9 969 Pfam PF00271 Helicase conserved C-terminal domain 494 603 9.5E-16 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS12045 2e2b8a252e34ede2073a8be908d020d9 969 SMART SM00487 150 342 1.5E-15 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS12045 2e2b8a252e34ede2073a8be908d020d9 969 SMART SM00490 519 603 2.7E-17 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS12045 2e2b8a252e34ede2073a8be908d020d9 969 Pfam PF00176 SNF2 family N-terminal domain 174 344 2.6E-16 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A6A12_RS12045 2e2b8a252e34ede2073a8be908d020d9 969 Gene3D G3DSA:3.40.50.300 484 946 1.7E-22 T 28-03-2018 A6A12_RS12045 2e2b8a252e34ede2073a8be908d020d9 969 Gene3D G3DSA:3.40.50.10810 155 411 4.2E-25 T 28-03-2018 A6A12_RS12045 2e2b8a252e34ede2073a8be908d020d9 969 Pfam PF12137 RNA polymerase recycling family C-terminal 607 966 1.0E-146 T 28-03-2018 IPR022737 RNA polymerase recycling, bacterial, C-terminal GO:0016817 A6A12_RS12045 2e2b8a252e34ede2073a8be908d020d9 969 SUPERFAMILY SSF52540 115 377 6.41E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12045 2e2b8a252e34ede2073a8be908d020d9 969 SUPERFAMILY SSF52540 482 651 1.11E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12045 2e2b8a252e34ede2073a8be908d020d9 969 SUPERFAMILY SSF52540 273 337 1.11E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12045 2e2b8a252e34ede2073a8be908d020d9 969 Hamap MF_01821 RNA polymerase-associated protein RapA [rapA]. 1 967 29.143 T 28-03-2018 IPR023949 RNA polymerase-associated protein RapA GO:0006355 A6A12_RS05350 af961283ec2bdb548cb7a27df59b79a0 66 Pfam PF14056 Domain of unknown function (DUF4250) 10 61 1.2E-18 T 28-03-2018 IPR025346 Protein of unknown function DUF4250 A6A12_RS00890 c1a1ed8e728929bc51c5650e98a3babd 217 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS00890 c1a1ed8e728929bc51c5650e98a3babd 217 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 30 7.0E-10 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS00890 c1a1ed8e728929bc51c5650e98a3babd 217 SUPERFAMILY SSF54523 41 203 2.93E-54 T 28-03-2018 A6A12_RS00890 c1a1ed8e728929bc51c5650e98a3babd 217 TIGRFAM TIGR01711 gspJ: type II secretion system protein J 8 199 3.4E-85 T 28-03-2018 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 A6A12_RS00890 c1a1ed8e728929bc51c5650e98a3babd 217 Pfam PF11612 Type II secretion system (T2SS), protein J 60 197 1.0E-38 T 28-03-2018 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 A6A12_RS00890 c1a1ed8e728929bc51c5650e98a3babd 217 Gene3D G3DSA:2.10.70.20 154 203 4.6E-16 T 28-03-2018 A6A12_RS00890 c1a1ed8e728929bc51c5650e98a3babd 217 Gene3D G3DSA:3.10.610.10 40 151 1.9E-35 T 28-03-2018 A6A12_RS00890 c1a1ed8e728929bc51c5650e98a3babd 217 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 30 5.3E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS04530 ca708d0a05dc6dae926dea32f01c9993 214 Pfam PF00406 Adenylate kinase 5 185 4.3E-59 T 28-03-2018 A6A12_RS04530 ca708d0a05dc6dae926dea32f01c9993 214 SUPERFAMILY SSF52540 1 188 7.39E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS04530 ca708d0a05dc6dae926dea32f01c9993 214 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A6A12_RS04530 ca708d0a05dc6dae926dea32f01c9993 214 PRINTS PR00094 Adenylate kinase signature 4 17 3.3E-35 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A6A12_RS04530 ca708d0a05dc6dae926dea32f01c9993 214 PRINTS PR00094 Adenylate kinase signature 32 46 3.3E-35 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A6A12_RS04530 ca708d0a05dc6dae926dea32f01c9993 214 PRINTS PR00094 Adenylate kinase signature 156 171 3.3E-35 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A6A12_RS04530 ca708d0a05dc6dae926dea32f01c9993 214 PRINTS PR00094 Adenylate kinase signature 173 187 3.3E-35 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A6A12_RS04530 ca708d0a05dc6dae926dea32f01c9993 214 PRINTS PR00094 Adenylate kinase signature 81 97 3.3E-35 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A6A12_RS04530 ca708d0a05dc6dae926dea32f01c9993 214 Gene3D G3DSA:3.40.50.300 1 214 1.5E-65 T 28-03-2018 A6A12_RS04530 ca708d0a05dc6dae926dea32f01c9993 214 Hamap MF_00235 Adenylate kinase [adk]. 1 214 52.41 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A6A12_RS04530 ca708d0a05dc6dae926dea32f01c9993 214 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 4.5E-75 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A6A12_RS04530 ca708d0a05dc6dae926dea32f01c9993 214 Pfam PF05191 Adenylate kinase, active site lid 123 158 4.0E-14 T 28-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A6A12_RS04720 8d1cc02506f7b4d9aea5e0c166256870 395 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 111 384 1.6E-80 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 A6A12_RS04720 8d1cc02506f7b4d9aea5e0c166256870 395 Pfam PF00425 chorismate binding enzyme 123 377 3.0E-71 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A6A12_RS04720 8d1cc02506f7b4d9aea5e0c166256870 395 Gene3D G3DSA:3.60.120.10 5 388 5.1E-89 T 28-03-2018 IPR005801 ADC synthase GO:0009058 A6A12_RS04720 8d1cc02506f7b4d9aea5e0c166256870 395 SUPERFAMILY SSF56322 25 387 1.19E-85 T 28-03-2018 IPR005801 ADC synthase GO:0009058 A6A12_RS12465 be01c28f3f3b7d0236a2029618fc83b5 63 SUPERFAMILY SSF46561 1 61 1.44E-22 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12465 be01c28f3f3b7d0236a2029618fc83b5 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 1.1E-23 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12465 be01c28f3f3b7d0236a2029618fc83b5 63 Gene3D G3DSA:1.10.287.310 1 63 7.6E-24 T 28-03-2018 A6A12_RS12465 be01c28f3f3b7d0236a2029618fc83b5 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.685 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12465 be01c28f3f3b7d0236a2029618fc83b5 63 Pfam PF00831 Ribosomal L29 protein 5 60 1.3E-24 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12465 be01c28f3f3b7d0236a2029618fc83b5 63 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 28-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS06540 422b6b8989dd32d5cab4893246bf08d4 353 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 350 1.1E-158 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A6A12_RS06540 422b6b8989dd32d5cab4893246bf08d4 353 SUPERFAMILY SSF51569 8 347 1.61E-130 T 28-03-2018 A6A12_RS06540 422b6b8989dd32d5cab4893246bf08d4 353 PIRSF PIRSF001361 1 353 7.7E-155 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A6A12_RS06540 422b6b8989dd32d5cab4893246bf08d4 353 Pfam PF00793 DAHP synthetase I family 44 338 1.2E-99 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A6A12_RS06540 422b6b8989dd32d5cab4893246bf08d4 353 Gene3D G3DSA:3.20.20.70 8 353 4.5E-123 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS06465 6f235f7d6bb67f9d4dacc1659ba4d292 436 SUPERFAMILY SSF56954 25 430 2.75E-88 T 28-03-2018 A6A12_RS06465 6f235f7d6bb67f9d4dacc1659ba4d292 436 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 24 430 5.5E-124 T 28-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 A6A12_RS06465 6f235f7d6bb67f9d4dacc1659ba4d292 436 Gene3D G3DSA:1.20.1600.10 21 426 2.9E-71 T 28-03-2018 A6A12_RS06465 6f235f7d6bb67f9d4dacc1659ba4d292 436 Pfam PF02321 Outer membrane efflux protein 233 416 2.1E-28 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A6A12_RS06465 6f235f7d6bb67f9d4dacc1659ba4d292 436 Pfam PF02321 Outer membrane efflux protein 26 212 3.2E-24 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A6A12_RS13515 56bee9e52d18e7a058ce7bdc8f1fff5a 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 6.0E-27 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS13515 56bee9e52d18e7a058ce7bdc8f1fff5a 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 21.305 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS13515 56bee9e52d18e7a058ce7bdc8f1fff5a 78 Gene3D G3DSA:2.30.170.40 2 75 3.2E-28 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS13515 56bee9e52d18e7a058ce7bdc8f1fff5a 78 SUPERFAMILY SSF143800 2 76 6.47E-30 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS13515 56bee9e52d18e7a058ce7bdc8f1fff5a 78 Pfam PF00830 Ribosomal L28 family 3 62 6.3E-26 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS04905 3fa12f120d09c363a820d11e88f45c04 181 Gene3D G3DSA:3.40.50.2020 2 180 5.5E-41 T 28-03-2018 A6A12_RS04905 3fa12f120d09c363a820d11e88f45c04 181 SUPERFAMILY SSF53271 12 178 1.99E-51 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A6A12_RS04905 3fa12f120d09c363a820d11e88f45c04 181 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 9 178 38.03 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 A6A12_RS04905 3fa12f120d09c363a820d11e88f45c04 181 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 9 177 2.7E-73 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 A6A12_RS04905 3fa12f120d09c363a820d11e88f45c04 181 Pfam PF00156 Phosphoribosyl transferase domain 30 154 1.9E-14 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A6A12_RS07115 b0aef844e59afa902f609fcee700b844 278 Gene3D G3DSA:1.10.10.10 7 116 4.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS07115 b0aef844e59afa902f609fcee700b844 278 Gene3D G3DSA:3.40.50.10490 117 278 2.7E-20 T 28-03-2018 A6A12_RS07115 b0aef844e59afa902f609fcee700b844 278 SUPERFAMILY SSF46689 9 85 5.55E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS07115 b0aef844e59afa902f609fcee700b844 278 SUPERFAMILY SSF53697 108 272 5.12E-22 T 28-03-2018 A6A12_RS07115 b0aef844e59afa902f609fcee700b844 278 Pfam PF01418 Helix-turn-helix domain, rpiR family 10 75 2.5E-12 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A6A12_RS07115 b0aef844e59afa902f609fcee700b844 278 Pfam PF01380 SIS domain 141 271 1.3E-20 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A6A12_RS13490 940252a817bd342a4f90638131dcac46 344 Gene3D G3DSA:3.40.50.2000 1 150 1.4E-29 T 28-03-2018 A6A12_RS13490 940252a817bd342a4f90638131dcac46 344 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 72 320 2.6E-17 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 A6A12_RS13490 940252a817bd342a4f90638131dcac46 344 Gene3D G3DSA:3.40.50.2000 167 343 1.4E-24 T 28-03-2018 A6A12_RS13490 940252a817bd342a4f90638131dcac46 344 SUPERFAMILY SSF53756 3 338 1.13E-62 T 28-03-2018 A6A12_RS10985 1b196a4720b0e020639927f7efb6ebed 415 Gene3D G3DSA:1.20.1440.110 49 151 6.6E-21 T 28-03-2018 A6A12_RS10985 1b196a4720b0e020639927f7efb6ebed 415 Hamap MF_01063 Esterase FrsA [frsA]. 4 415 55.31 T 28-03-2018 IPR010520 UPF0255 family A6A12_RS10985 1b196a4720b0e020639927f7efb6ebed 415 Gene3D G3DSA:3.40.50.1820 152 396 6.0E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS10985 1b196a4720b0e020639927f7efb6ebed 415 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 6 413 1.6E-226 T 28-03-2018 IPR010520 UPF0255 family A6A12_RS10985 1b196a4720b0e020639927f7efb6ebed 415 SUPERFAMILY SSF53474 48 411 1.03E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 SUPERFAMILY SSF158472 199 246 1.83E-6 T 28-03-2018 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 Gene3D G3DSA:1.20.120.160 811 925 1.1E-17 T 28-03-2018 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 Gene3D G3DSA:3.40.50.2300 658 810 2.1E-37 T 28-03-2018 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 Gene3D G3DSA:3.40.50.2300 528 646 8.4E-5 T 28-03-2018 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 470 2.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 PRINTS PR00344 Bacterial sensor protein C-terminal signature 477 495 2.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 456 2.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 PRINTS PR00344 Bacterial sensor protein C-terminal signature 501 514 2.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 SUPERFAMILY SSF47226 760 773 9.68E-21 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 SUPERFAMILY SSF47226 813 916 9.68E-21 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 SMART SM00448 664 777 2.3E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 Gene3D G3DSA:1.10.287.130 279 350 3.3E-21 T 28-03-2018 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 Pfam PF01627 Hpt domain 833 917 7.1E-12 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 SUPERFAMILY SSF47384 274 355 1.06E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 Pfam PF09984 Uncharacterised signal transduction histidine kinase domain (DUF2222) 31 174 1.6E-53 T 28-03-2018 IPR019247 Histidine kinase BarA, N-terminal A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 SMART SM00388 289 354 1.4E-24 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 Pfam PF00072 Response regulator receiver domain 666 776 3.2E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 SUPERFAMILY SSF52172 533 656 2.13E-7 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 SMART SM00304 197 249 5.1E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 SUPERFAMILY SSF55874 343 515 1.26E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 401 516 7.5E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 SMART SM00073 823 921 7.5E-6 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 SUPERFAMILY SSF52172 663 785 2.42E-36 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 Gene3D G3DSA:3.30.565.10 358 525 6.6E-48 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 SMART SM00387 401 517 7.1E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS11775 3b288726a74a383d966267718e25be0a 926 Pfam PF00512 His Kinase A (phospho-acceptor) domain 290 354 1.1E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS01155 5b23d0e29da1ea2785d539d5e027bfc3 126 PRINTS PR01650 Bacterial translocase SecE signature 110 126 1.3E-40 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 A6A12_RS01155 5b23d0e29da1ea2785d539d5e027bfc3 126 PRINTS PR01650 Bacterial translocase SecE signature 66 86 1.3E-40 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 A6A12_RS01155 5b23d0e29da1ea2785d539d5e027bfc3 126 PRINTS PR01650 Bacterial translocase SecE signature 90 110 1.3E-40 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 A6A12_RS01155 5b23d0e29da1ea2785d539d5e027bfc3 126 PRINTS PR01650 Bacterial translocase SecE signature 45 66 1.3E-40 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 A6A12_RS01155 5b23d0e29da1ea2785d539d5e027bfc3 126 Gene3D G3DSA:1.20.5.1030 69 120 2.0E-19 T 28-03-2018 A6A12_RS01155 5b23d0e29da1ea2785d539d5e027bfc3 126 Hamap MF_00422 Protein translocase subunit SecE [secE]. 67 122 13.338 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A6A12_RS01155 5b23d0e29da1ea2785d539d5e027bfc3 126 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 70 124 8.0E-18 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 A6A12_RS01155 5b23d0e29da1ea2785d539d5e027bfc3 126 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 71 122 8.8E-21 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A6A12_RS01155 5b23d0e29da1ea2785d539d5e027bfc3 126 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 72 100 - T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A6A12_RS05730 eb3739df036a0d6160605d69d727381d 405 Gene3D G3DSA:3.90.550.10 4 305 6.2E-59 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS05730 eb3739df036a0d6160605d69d727381d 405 Pfam PF00483 Nucleotidyl transferase 6 273 1.0E-61 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A6A12_RS05730 eb3739df036a0d6160605d69d727381d 405 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 10 29 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 A6A12_RS05730 eb3739df036a0d6160605d69d727381d 405 SUPERFAMILY SSF51161 293 402 3.01E-20 T 28-03-2018 IPR011004 Trimeric LpxA-like A6A12_RS05730 eb3739df036a0d6160605d69d727381d 405 SUPERFAMILY SSF53448 4 275 5.63E-68 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS05730 eb3739df036a0d6160605d69d727381d 405 SUPERFAMILY SSF53448 341 357 5.63E-68 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS05730 eb3739df036a0d6160605d69d727381d 405 Gene3D G3DSA:2.160.10.10 306 405 6.7E-14 T 28-03-2018 A6A12_RS05730 eb3739df036a0d6160605d69d727381d 405 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 95 103 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 A6A12_RS05730 eb3739df036a0d6160605d69d727381d 405 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 1 403 48.824 T 28-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 A6A12_RS05730 eb3739df036a0d6160605d69d727381d 405 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 193 203 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 A6A12_RS05730 eb3739df036a0d6160605d69d727381d 405 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 335 361 5.8E-4 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS05730 eb3739df036a0d6160605d69d727381d 405 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 4 377 3.6E-150 T 28-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 A6A12_RS10055 415a656e1217f3be6fa3bd0be2399e39 181 Gene3D G3DSA:1.20.1380.10 76 177 3.6E-39 T 28-03-2018 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 A6A12_RS10055 415a656e1217f3be6fa3bd0be2399e39 181 SUPERFAMILY SSF82808 67 180 9.68E-48 T 28-03-2018 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 A6A12_RS10055 415a656e1217f3be6fa3bd0be2399e39 181 PIRSF PIRSF019401 1 181 9.1E-56 T 28-03-2018 IPR005621 Negative modulator of initiation of replication SeqA GO:0003677|GO:0032297 A6A12_RS10055 415a656e1217f3be6fa3bd0be2399e39 181 Pfam PF17206 SeqA protein N-terminal domain 1 36 1.3E-24 T 28-03-2018 IPR033761 Negative modulator of initiation of replication SeqA, N-terminal A6A12_RS10055 415a656e1217f3be6fa3bd0be2399e39 181 Gene3D G3DSA:1.10.1220.10 1 37 1.6E-25 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A6A12_RS10055 415a656e1217f3be6fa3bd0be2399e39 181 Pfam PF03925 SeqA protein C-terminal domain 72 179 1.1E-45 T 28-03-2018 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 A6A12_RS10055 415a656e1217f3be6fa3bd0be2399e39 181 SUPERFAMILY SSF47598 1 34 6.23E-14 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 A6A12_RS10055 415a656e1217f3be6fa3bd0be2399e39 181 Hamap MF_00908 Negative modulator of initiation of replication [seqA]. 1 181 42.282 T 28-03-2018 IPR005621 Negative modulator of initiation of replication SeqA GO:0003677|GO:0032297 A6A12_RS13075 093f8cb24f723b144ee3472ed1b2b578 608 SUPERFAMILY SSF51206 8 129 7.07E-15 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like A6A12_RS13075 093f8cb24f723b144ee3472ed1b2b578 608 Gene3D G3DSA:2.60.120.10 3 141 2.6E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS13075 093f8cb24f723b144ee3472ed1b2b578 608 Gene3D G3DSA:3.10.580.10 145 283 6.2E-15 T 28-03-2018 A6A12_RS13075 093f8cb24f723b144ee3472ed1b2b578 608 SUPERFAMILY SSF54631 144 276 8.79E-18 T 28-03-2018 A6A12_RS13075 093f8cb24f723b144ee3472ed1b2b578 608 SUPERFAMILY SSF81593 500 600 7.69E-5 T 28-03-2018 A6A12_RS13075 093f8cb24f723b144ee3472ed1b2b578 608 Pfam PF00027 Cyclic nucleotide-binding domain 32 112 4.3E-9 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A6A12_RS13075 093f8cb24f723b144ee3472ed1b2b578 608 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 471 604 6.8E-40 T 28-03-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding A6A12_RS13075 093f8cb24f723b144ee3472ed1b2b578 608 Pfam PF03445 Putative nucleotidyltransferase DUF294 302 432 1.2E-40 T 28-03-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 A6A12_RS13075 093f8cb24f723b144ee3472ed1b2b578 608 Gene3D G3DSA:1.20.120.330 496 600 1.4E-5 T 28-03-2018 A6A12_RS03585 ab91a59195a078def71037c83dfb697b 443 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 11 359 5.5E-135 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A6A12_RS03585 ab91a59195a078def71037c83dfb697b 443 Pfam PF13742 OB-fold nucleic acid binding domain 10 103 3.7E-29 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 A6A12_RS03585 ab91a59195a078def71037c83dfb697b 443 Pfam PF02601 Exonuclease VII, large subunit 126 438 6.5E-102 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 A6A12_RS03585 ab91a59195a078def71037c83dfb697b 443 Gene3D G3DSA:2.40.50.140 4 104 3.5E-6 T 28-03-2018 A6A12_RS03585 ab91a59195a078def71037c83dfb697b 443 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 7 443 30.742 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 A6A12_RS02205 7a439abebc2f1947791296b8345ff7f2 455 Gene3D G3DSA:1.10.443.10 233 408 3.6E-23 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS02205 7a439abebc2f1947791296b8345ff7f2 455 Gene3D G3DSA:1.10.150.130 106 232 1.1E-9 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A6A12_RS02205 7a439abebc2f1947791296b8345ff7f2 455 SUPERFAMILY SSF56349 113 406 2.35E-44 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS02205 7a439abebc2f1947791296b8345ff7f2 455 Pfam PF13356 Arm DNA-binding domain 2 93 9.8E-11 T 28-03-2018 IPR025166 Integrase, DNA-binding domain A6A12_RS02205 7a439abebc2f1947791296b8345ff7f2 455 Pfam PF00589 Phage integrase family 241 373 4.8E-14 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 SUPERFAMILY SSF82714 706 788 3.92E-5 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 Pfam PF00873 AcrB/AcrD/AcrF family 5 1021 2.3E-175 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 Gene3D G3DSA:3.30.70.1430 566 655 1.1E-8 T 28-03-2018 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 SUPERFAMILY SSF82693 141 181 3.92E-12 T 28-03-2018 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 SUPERFAMILY SSF82693 267 325 3.92E-12 T 28-03-2018 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 SUPERFAMILY SSF82866 788 1023 1.83E-49 T 28-03-2018 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 SUPERFAMILY SSF82714 184 263 4.58E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 SUPERFAMILY SSF82693 41 133 2.62E-23 T 28-03-2018 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 Gene3D G3DSA:3.30.70.1430 41 143 3.7E-25 T 28-03-2018 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 Gene3D G3DSA:1.20.1640.10 791 1024 1.1E-44 T 28-03-2018 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 Gene3D G3DSA:1.20.1640.10 266 492 3.9E-43 T 28-03-2018 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 Gene3D G3DSA:3.30.2090.10 180 265 2.0E-10 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 Gene3D G3DSA:3.30.2090.10 705 790 1.0E-8 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 5.4E-30 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 5.4E-30 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 5.4E-30 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 5.4E-30 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 PRINTS PR00702 Acriflavin resistance protein family signature 550 567 5.4E-30 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 5.4E-30 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 5.4E-30 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS02880 6faa4da5475e36f49c7ad5f5f99f245a 1032 SUPERFAMILY SSF82866 289 491 2.75E-40 T 28-03-2018 A6A12_RS14380 f5bcf36667b912568ba8c005e2b8aaad 276 Gene3D G3DSA:1.20.120.220 98 274 5.2E-53 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14380 f5bcf36667b912568ba8c005e2b8aaad 276 Pfam PF00119 ATP synthase A chain 50 268 9.7E-58 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14380 f5bcf36667b912568ba8c005e2b8aaad 276 Hamap MF_01393 ATP synthase subunit a [atpB]. 14 274 15.517 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14380 f5bcf36667b912568ba8c005e2b8aaad 276 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 41 269 3.5E-45 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14380 f5bcf36667b912568ba8c005e2b8aaad 276 SUPERFAMILY SSF81336 99 268 6.02E-50 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14380 f5bcf36667b912568ba8c005e2b8aaad 276 ProSitePatterns PS00449 ATP synthase a subunit signature. 209 218 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14380 f5bcf36667b912568ba8c005e2b8aaad 276 PRINTS PR00123 ATP synthase A subunit signature 254 269 3.8E-14 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14380 f5bcf36667b912568ba8c005e2b8aaad 276 PRINTS PR00123 ATP synthase A subunit signature 107 123 3.8E-14 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14380 f5bcf36667b912568ba8c005e2b8aaad 276 PRINTS PR00123 ATP synthase A subunit signature 206 228 3.8E-14 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS13415 9e9c74ca5b1317cd392d3551ebe686a8 354 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 326 3.6E-97 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS13415 9e9c74ca5b1317cd392d3551ebe686a8 354 Gene3D G3DSA:3.40.50.720 1 231 1.3E-56 T 28-03-2018 A6A12_RS13415 9e9c74ca5b1317cd392d3551ebe686a8 354 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 339 1.9E-157 T 28-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 A6A12_RS13415 9e9c74ca5b1317cd392d3551ebe686a8 354 Gene3D G3DSA:3.90.25.10 232 336 4.0E-29 T 28-03-2018 A6A12_RS13415 9e9c74ca5b1317cd392d3551ebe686a8 354 SUPERFAMILY SSF51735 1 337 3.08E-93 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS12715 b91060f83347c856e06b5c257c647aa1 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.7E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS12715 b91060f83347c856e06b5c257c647aa1 296 SUPERFAMILY SSF46785 1 86 1.29E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS12715 b91060f83347c856e06b5c257c647aa1 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS12715 b91060f83347c856e06b5c257c647aa1 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS12715 b91060f83347c856e06b5c257c647aa1 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS12715 b91060f83347c856e06b5c257c647aa1 296 Gene3D G3DSA:3.40.190.10 176 264 7.5E-24 T 28-03-2018 A6A12_RS12715 b91060f83347c856e06b5c257c647aa1 296 Gene3D G3DSA:1.10.10.10 1 86 1.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS12715 b91060f83347c856e06b5c257c647aa1 296 Pfam PF03466 LysR substrate binding domain 88 292 5.3E-43 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS12715 b91060f83347c856e06b5c257c647aa1 296 SUPERFAMILY SSF53850 89 294 2.08E-38 T 28-03-2018 A6A12_RS12715 b91060f83347c856e06b5c257c647aa1 296 Gene3D G3DSA:3.40.190.10 87 175 2.9E-20 T 28-03-2018 A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 350 2.6E-139 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 SUPERFAMILY SSF49493 260 345 7.98E-23 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 Gene3D G3DSA:2.60.260.20 198 255 6.3E-19 T 28-03-2018 A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 Gene3D G3DSA:2.60.260.20 256 367 9.7E-29 T 28-03-2018 A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 28-03-2018 IPR018253 DnaJ domain, conserved site A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 SUPERFAMILY SSF46565 1 108 7.72E-35 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 374 42.496 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 SMART SM00271 4 62 1.3E-29 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 PRINTS PR00625 DnaJ domain signature 7 25 4.6E-32 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 PRINTS PR00625 DnaJ domain signature 62 81 4.6E-32 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 PRINTS PR00625 DnaJ domain signature 25 40 4.6E-32 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 PRINTS PR00625 DnaJ domain signature 42 62 4.6E-32 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 SUPERFAMILY SSF49493 115 139 7.98E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 SUPERFAMILY SSF49493 187 261 7.98E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 Gene3D G3DSA:2.10.230.10 146 197 6.8E-19 T 28-03-2018 A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 Pfam PF00226 DnaJ domain 5 67 3.0E-26 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 SUPERFAMILY SSF57938 135 211 4.84E-22 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 Gene3D G3DSA:1.10.287.110 1 116 7.5E-34 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 Pfam PF01556 DnaJ C terminal domain 122 334 7.0E-46 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal A6A12_RS03905 e654f4d11b91351375af922bdc3db235 380 Pfam PF00684 DnaJ central domain 148 208 9.0E-15 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 A6A12_RS10150 13cd13a9be47d09d8e8b7850841c9d9e 176 Pfam PF01713 Smr domain 97 171 1.0E-18 T 28-03-2018 IPR002625 Smr domain A6A12_RS10150 13cd13a9be47d09d8e8b7850841c9d9e 176 SUPERFAMILY SSF160443 95 171 4.32E-12 T 28-03-2018 IPR002625 Smr domain A6A12_RS10150 13cd13a9be47d09d8e8b7850841c9d9e 176 SMART SM00463 94 172 2.8E-17 T 28-03-2018 IPR002625 Smr domain A6A12_RS10150 13cd13a9be47d09d8e8b7850841c9d9e 176 Hamap MF_01042 UPF0115 protein YfcN [yfcN]. 1 173 38.182 T 28-03-2018 IPR022990 Uncharacterised protein family UPF0115 A6A12_RS10950 747a65ea63afb61671fb971c372d92bd 369 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 198 5.4E-84 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A6A12_RS10950 747a65ea63afb61671fb971c372d92bd 369 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 7 199 2.9E-74 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A6A12_RS10950 747a65ea63afb61671fb971c372d92bd 369 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 38.22 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A6A12_RS10950 747a65ea63afb61671fb971c372d92bd 369 SUPERFAMILY SSF142695 205 367 2.35E-47 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A6A12_RS10950 747a65ea63afb61671fb971c372d92bd 369 Pfam PF00925 GTP cyclohydrolase II 207 367 4.0E-39 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A6A12_RS10950 747a65ea63afb61671fb971c372d92bd 369 PIRSF PIRSF001259 3 369 2.9E-130 T 28-03-2018 A6A12_RS10950 747a65ea63afb61671fb971c372d92bd 369 Gene3D G3DSA:3.90.870.10 2 212 8.8E-94 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain A6A12_RS10950 747a65ea63afb61671fb971c372d92bd 369 SUPERFAMILY SSF55821 3 202 4.35E-86 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain A6A12_RS01040 abd3698369932efbcceb7ab72fb41fd5 436 Gene3D G3DSA:3.40.50.300 238 435 4.9E-44 T 28-03-2018 A6A12_RS01040 abd3698369932efbcceb7ab72fb41fd5 436 Pfam PF00270 DEAD/DEAH box helicase 33 207 5.2E-46 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A6A12_RS01040 abd3698369932efbcceb7ab72fb41fd5 436 SMART SM00490 270 351 1.5E-32 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS01040 abd3698369932efbcceb7ab72fb41fd5 436 SMART SM00487 28 234 3.3E-55 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS01040 abd3698369932efbcceb7ab72fb41fd5 436 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 8 389 50.209 T 28-03-2018 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 A6A12_RS01040 abd3698369932efbcceb7ab72fb41fd5 436 Gene3D G3DSA:3.40.50.300 2 237 8.1E-53 T 28-03-2018 A6A12_RS01040 abd3698369932efbcceb7ab72fb41fd5 436 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 163 171 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A6A12_RS01040 abd3698369932efbcceb7ab72fb41fd5 436 SUPERFAMILY SSF52540 85 365 1.94E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01040 abd3698369932efbcceb7ab72fb41fd5 436 Pfam PF00271 Helicase conserved C-terminal domain 245 351 5.3E-30 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS13185 39a8e34d1387b131a76a2cd87b37d49a 361 Pfam PF00953 Glycosyl transferase family 4 71 227 3.5E-29 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A6A12_RS13185 39a8e34d1387b131a76a2cd87b37d49a 361 TIGRFAM TIGR02380 ECA_wecA: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase 3 345 2.8E-158 T 28-03-2018 IPR012750 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase GO:0000287|GO:0009103|GO:0009276|GO:0016021|GO:0016780|GO:0030145 MetaCyc: PWY-7290|MetaCyc: PWY-7530|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 A6A12_RS13185 39a8e34d1387b131a76a2cd87b37d49a 361 Hamap MF_02030 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase [wecA]. 4 348 27.225 T 28-03-2018 IPR012750 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase GO:0000287|GO:0009103|GO:0009276|GO:0016021|GO:0016780|GO:0030145 MetaCyc: PWY-7290|MetaCyc: PWY-7530|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 A6A12_RS10375 2399c673de0a5bb4433d7efdf9306184 346 Gene3D G3DSA:1.10.10.60 15 44 2.2E-4 T 28-03-2018 A6A12_RS10375 2399c673de0a5bb4433d7efdf9306184 346 SUPERFAMILY SSF53098 160 333 3.13E-38 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS10375 2399c673de0a5bb4433d7efdf9306184 346 Gene3D G3DSA:3.30.420.10 156 341 3.9E-30 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS10375 2399c673de0a5bb4433d7efdf9306184 346 Pfam PF00665 Integrase core domain 161 283 3.7E-21 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A6A12_RS10375 2399c673de0a5bb4433d7efdf9306184 346 Pfam PF13551 Winged helix-turn helix 11 74 6.4E-20 T 28-03-2018 A6A12_RS10375 2399c673de0a5bb4433d7efdf9306184 346 SUPERFAMILY SSF46689 18 113 1.34E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS09425 a244fe754bb3b192660acda45572900d 218 SUPERFAMILY SSF52172 1 118 5.12E-35 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS09425 a244fe754bb3b192660acda45572900d 218 Gene3D G3DSA:1.10.10.10 119 218 1.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09425 a244fe754bb3b192660acda45572900d 218 Pfam PF00072 Response regulator receiver domain 4 112 8.7E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS09425 a244fe754bb3b192660acda45572900d 218 Gene3D G3DSA:3.40.50.2300 1 118 1.4E-31 T 28-03-2018 A6A12_RS09425 a244fe754bb3b192660acda45572900d 218 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 1.1E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS09425 a244fe754bb3b192660acda45572900d 218 SMART SM00448 1 112 1.9E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS09425 a244fe754bb3b192660acda45572900d 218 SUPERFAMILY SSF46894 118 216 1.36E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS09425 a244fe754bb3b192660acda45572900d 218 SMART SM00862 145 216 9.9E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS05810 bd22575eeded7052dbcb56ebcf57e1ae 287 SUPERFAMILY SSF50630 149 283 2.44E-41 T 28-03-2018 IPR021109 Aspartic peptidase domain A6A12_RS05810 bd22575eeded7052dbcb56ebcf57e1ae 287 Pfam PF05618 Putative ATP-dependant zinc protease 149 285 5.7E-47 T 28-03-2018 A6A12_RS05810 bd22575eeded7052dbcb56ebcf57e1ae 287 Gene3D G3DSA:1.20.5.340 58 156 7.9E-4 T 28-03-2018 A6A12_RS05810 bd22575eeded7052dbcb56ebcf57e1ae 287 Gene3D G3DSA:2.40.70.10 157 276 1.6E-44 T 28-03-2018 IPR021109 Aspartic peptidase domain A6A12_RS05700 c5a0b32d2e825708f74c72df09347070 72 SMART SM00316 4 72 5.4E-6 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS05700 c5a0b32d2e825708f74c72df09347070 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 7.8E-39 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A6A12_RS05700 c5a0b32d2e825708f74c72df09347070 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 7.1E-28 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 A6A12_RS05700 c5a0b32d2e825708f74c72df09347070 72 Gene3D G3DSA:2.40.50.140 1 72 2.0E-36 T 28-03-2018 A6A12_RS05700 c5a0b32d2e825708f74c72df09347070 72 SUPERFAMILY SSF50249 1 70 6.86E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS05700 c5a0b32d2e825708f74c72df09347070 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.394 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 A6A12_RS10785 5ca89f23621f8a442926de65205990fe 155 Hamap MF_00042 Ribonuclease H [rnhA]. 2 149 35.966 T 28-03-2018 IPR022892 Ribonuclease HI GO:0004523 A6A12_RS10785 5ca89f23621f8a442926de65205990fe 155 SUPERFAMILY SSF53098 3 143 1.9E-57 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS10785 5ca89f23621f8a442926de65205990fe 155 Gene3D G3DSA:3.30.420.10 1 154 6.9E-52 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS10785 5ca89f23621f8a442926de65205990fe 155 Pfam PF00075 RNase H 3 142 7.5E-53 T 28-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 A6A12_RS04455 7c12384a90648440adf9963b4963f4c3 274 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 137 264 2.6E-46 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 A6A12_RS04455 7c12384a90648440adf9963b4963f4c3 274 Hamap MF_00509 Cell division protein ZipA [zipA]. 2 267 22.658 T 28-03-2018 IPR011919 Cell division protein ZipA GO:0007049|GO:0016021|GO:0090529 A6A12_RS04455 7c12384a90648440adf9963b4963f4c3 274 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 138 269 4.0E-67 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 A6A12_RS04455 7c12384a90648440adf9963b4963f4c3 274 SUPERFAMILY SSF64383 137 270 1.57E-48 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 A6A12_RS04455 7c12384a90648440adf9963b4963f4c3 274 SMART SM00771 135 265 2.4E-71 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 A6A12_RS04455 7c12384a90648440adf9963b4963f4c3 274 TIGRFAM TIGR02205 septum_zipA: cell division protein ZipA 3 265 7.0E-84 T 28-03-2018 IPR011919 Cell division protein ZipA GO:0007049|GO:0016021|GO:0090529 A6A12_RS04455 7c12384a90648440adf9963b4963f4c3 274 Gene3D G3DSA:3.30.1400.10 137 268 3.0E-50 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 SUPERFAMILY SSF53067 19 196 1.75E-50 T 28-03-2018 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 Gene3D G3DSA:2.60.34.10 387 528 4.2E-49 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 SUPERFAMILY SSF100934 504 616 2.75E-34 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 205 218 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 SUPERFAMILY SSF100920 384 537 1.24E-50 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 Pfam PF00012 Hsp70 protein 22 601 7.0E-195 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 PRINTS PR00301 70kDa heat shock protein signature 329 345 9.1E-55 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 PRINTS PR00301 70kDa heat shock protein signature 360 380 9.1E-55 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 PRINTS PR00301 70kDa heat shock protein signature 20 33 9.1E-55 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 PRINTS PR00301 70kDa heat shock protein signature 466 482 9.1E-55 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 PRINTS PR00301 70kDa heat shock protein signature 48 60 9.1E-55 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 PRINTS PR00301 70kDa heat shock protein signature 152 172 9.1E-55 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 PRINTS PR00301 70kDa heat shock protein signature 211 221 9.1E-55 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 PRINTS PR00301 70kDa heat shock protein signature 385 404 9.1E-55 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 Gene3D G3DSA:1.20.1270.10 529 616 7.2E-14 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 Gene3D G3DSA:3.30.420.40 19 208 3.1E-58 T 28-03-2018 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 Gene3D G3DSA:3.30.420.40 209 358 4.0E-39 T 28-03-2018 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 617 45.982 T 28-03-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 SUPERFAMILY SSF53067 200 377 4.18E-51 T 28-03-2018 A6A12_RS03520 7553aa1ab2d553a7e565d8a3bffb10fa 617 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 616 3.7E-266 T 28-03-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 A6A12_RS05040 e6352b87fe52f2a9aae927f8a75ff875 270 Pfam PF13614 AAA domain 3 161 2.6E-19 T 28-03-2018 IPR025669 AAA domain A6A12_RS05040 e6352b87fe52f2a9aae927f8a75ff875 270 SUPERFAMILY SSF52540 1 268 1.46E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05040 e6352b87fe52f2a9aae927f8a75ff875 270 PIRSF PIRSF003092 1 270 1.1E-94 T 28-03-2018 IPR025501 ATP binding protein MinD A6A12_RS05040 e6352b87fe52f2a9aae927f8a75ff875 270 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 268 1.1E-110 T 28-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 A6A12_RS05040 e6352b87fe52f2a9aae927f8a75ff875 270 Gene3D G3DSA:3.40.50.300 1 259 8.1E-55 T 28-03-2018 A6A12_RS14340 7c0f790680353337b89b0617dc3f7134 453 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 451 1.8E-205 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 A6A12_RS14340 7c0f790680353337b89b0617dc3f7134 453 Gene3D G3DSA:3.90.550.10 1 241 1.5E-51 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS14340 7c0f790680353337b89b0617dc3f7134 453 Gene3D G3DSA:2.160.10.10 308 437 1.4E-33 T 28-03-2018 A6A12_RS14340 7c0f790680353337b89b0617dc3f7134 453 SUPERFAMILY SSF51161 253 434 1.68E-48 T 28-03-2018 IPR011004 Trimeric LpxA-like A6A12_RS14340 7c0f790680353337b89b0617dc3f7134 453 Pfam PF12804 MobA-like NTP transferase domain 5 129 3.3E-23 T 28-03-2018 IPR025877 MobA-like NTP transferase A6A12_RS14340 7c0f790680353337b89b0617dc3f7134 453 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 400 428 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A6A12_RS14340 7c0f790680353337b89b0617dc3f7134 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 265 296 2.3E-6 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS14340 7c0f790680353337b89b0617dc3f7134 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 297 330 3.1E-5 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS14340 7c0f790680353337b89b0617dc3f7134 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 392 424 4.4E-7 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS14340 7c0f790680353337b89b0617dc3f7134 453 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 449 42.385 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 A6A12_RS14340 7c0f790680353337b89b0617dc3f7134 453 Gene3D G3DSA:2.160.10.10 242 307 6.9E-17 T 28-03-2018 A6A12_RS14340 7c0f790680353337b89b0617dc3f7134 453 SUPERFAMILY SSF53448 1 249 3.13E-64 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS12250 4d891f2120a780a1023ec780d0794ea9 570 Pfam PF17243 POTRA domain TamA domain 1 25 95 1.3E-18 T 28-03-2018 IPR035243 TamA, POTRA domain 1 A6A12_RS12250 4d891f2120a780a1023ec780d0794ea9 570 Pfam PF01103 Surface antigen 279 567 3.5E-27 T 28-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 A6A12_RS12250 4d891f2120a780a1023ec780d0794ea9 570 Gene3D G3DSA:3.10.20.310 96 184 5.6E-12 T 28-03-2018 A6A12_RS12250 4d891f2120a780a1023ec780d0794ea9 570 Gene3D G3DSA:2.40.160.50 216 569 1.7E-56 T 28-03-2018 A6A12_RS02545 3d08f050e5ac3e3c2f73780218465018 424 SMART SM01091 342 420 7.2E-22 T 28-03-2018 IPR005170 Transporter-associated domain A6A12_RS02545 3d08f050e5ac3e3c2f73780218465018 424 SUPERFAMILY SSF56176 340 421 1.69E-20 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A6A12_RS02545 3d08f050e5ac3e3c2f73780218465018 424 Pfam PF00571 CBS domain 278 326 0.0025 T 28-03-2018 IPR000644 CBS domain A6A12_RS02545 3d08f050e5ac3e3c2f73780218465018 424 Gene3D G3DSA:3.30.465.10 337 419 1.0E-16 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A6A12_RS02545 3d08f050e5ac3e3c2f73780218465018 424 Pfam PF01595 Domain of unknown function DUF21 14 181 2.8E-49 T 28-03-2018 IPR002550 Domain of unknown function DUF21 A6A12_RS02545 3d08f050e5ac3e3c2f73780218465018 424 Gene3D G3DSA:3.10.580.10 185 336 3.0E-20 T 28-03-2018 A6A12_RS02545 3d08f050e5ac3e3c2f73780218465018 424 Pfam PF03471 Transporter associated domain 344 418 4.5E-17 T 28-03-2018 IPR005170 Transporter-associated domain A6A12_RS02545 3d08f050e5ac3e3c2f73780218465018 424 SUPERFAMILY SSF54631 192 329 3.54E-24 T 28-03-2018 A6A12_RS04155 7b1753e5584c5c3f8ce46ffae8094c5a 315 Pfam PF13377 Periplasmic binding protein-like domain 168 309 1.4E-18 T 28-03-2018 A6A12_RS04155 7b1753e5584c5c3f8ce46ffae8094c5a 315 SUPERFAMILY SSF53822 63 308 2.55E-57 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A6A12_RS04155 7b1753e5584c5c3f8ce46ffae8094c5a 315 SMART SM00354 4 74 7.5E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS04155 7b1753e5584c5c3f8ce46ffae8094c5a 315 Gene3D G3DSA:3.40.50.2300 57 173 3.3E-18 T 28-03-2018 A6A12_RS04155 7b1753e5584c5c3f8ce46ffae8094c5a 315 SUPERFAMILY SSF47413 4 60 1.2E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS04155 7b1753e5584c5c3f8ce46ffae8094c5a 315 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 50 1.7E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS04155 7b1753e5584c5c3f8ce46ffae8094c5a 315 TIGRFAM TIGR02405 trehalos_R_Ecol: trehalose operon repressor 4 311 2.0E-133 T 28-03-2018 IPR012771 Trehalose operon repressor GO:0003677|GO:0005991|GO:0045892 A6A12_RS04155 7b1753e5584c5c3f8ce46ffae8094c5a 315 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 28-03-2018 A6A12_RS04155 7b1753e5584c5c3f8ce46ffae8094c5a 315 Gene3D G3DSA:1.10.260.40 5 56 5.7E-17 T 28-03-2018 A6A12_RS04155 7b1753e5584c5c3f8ce46ffae8094c5a 315 Gene3D G3DSA:3.40.50.2300 174 304 2.4E-24 T 28-03-2018 A6A12_RS09960 e32f4d84eee1743ea168c427943cfe72 76 SUPERFAMILY SSF46785 1 54 2.52E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09960 e32f4d84eee1743ea168c427943cfe72 76 Gene3D G3DSA:1.10.10.10 1 73 4.3E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09960 e32f4d84eee1743ea168c427943cfe72 76 Pfam PF09012 FeoC like transcriptional regulator 2 54 3.4E-13 T 28-03-2018 IPR015102 Transcriptional regulator HTH-type, FeoC A6A12_RS10590 6639afcfb11a48301cb5bbdfe15809fc 379 Pfam PF07196 Flagellin hook IN motif 200 248 3.1E-8 T 28-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 A6A12_RS10590 6639afcfb11a48301cb5bbdfe15809fc 379 Pfam PF00700 Bacterial flagellin C-terminal helical region 295 378 5.9E-26 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A6A12_RS10590 6639afcfb11a48301cb5bbdfe15809fc 379 PRINTS PR00207 Flagellin signature 111 134 1.2E-24 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A6A12_RS10590 6639afcfb11a48301cb5bbdfe15809fc 379 PRINTS PR00207 Flagellin signature 37 54 1.2E-24 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A6A12_RS10590 6639afcfb11a48301cb5bbdfe15809fc 379 PRINTS PR00207 Flagellin signature 76 95 1.2E-24 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A6A12_RS10590 6639afcfb11a48301cb5bbdfe15809fc 379 Gene3D G3DSA:1.20.1330.10 40 351 1.7E-70 T 28-03-2018 A6A12_RS10590 6639afcfb11a48301cb5bbdfe15809fc 379 SUPERFAMILY SSF64518 1 379 2.22E-97 T 28-03-2018 A6A12_RS10590 6639afcfb11a48301cb5bbdfe15809fc 379 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 1.3E-41 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A6A12_RS07840 4a7eb25213d0e157faf80c45cc8c6ece 665 SUPERFAMILY SSF69279 208 359 4.25E-21 T 28-03-2018 A6A12_RS07840 4a7eb25213d0e157faf80c45cc8c6ece 665 SUPERFAMILY SSF69349 437 616 1.33E-25 T 28-03-2018 A6A12_RS07840 4a7eb25213d0e157faf80c45cc8c6ece 665 SUPERFAMILY SSF69255 359 447 8.37E-32 T 28-03-2018 A6A12_RS07840 4a7eb25213d0e157faf80c45cc8c6ece 665 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 22 513 5.0E-135 T 28-03-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset A6A12_RS07840 4a7eb25213d0e157faf80c45cc8c6ece 665 Gene3D G3DSA:3.55.50.10 102 193 6.0E-21 T 28-03-2018 A6A12_RS07840 4a7eb25213d0e157faf80c45cc8c6ece 665 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 27 498 2.6E-91 T 28-03-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein A6A12_RS07840 4a7eb25213d0e157faf80c45cc8c6ece 665 Gene3D G3DSA:2.40.50.230 365 447 9.5E-34 T 28-03-2018 IPR006531 Gp5 N-terminal A6A12_RS07840 4a7eb25213d0e157faf80c45cc8c6ece 665 Pfam PF05954 Phage late control gene D protein (GPD) 34 330 2.3E-52 T 28-03-2018 A6A12_RS07840 4a7eb25213d0e157faf80c45cc8c6ece 665 SUPERFAMILY SSF69279 16 189 1.36E-34 T 28-03-2018 A6A12_RS02440 1db4080cab15fd146094fc609d4aa300 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 269 8.7E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS02440 1db4080cab15fd146094fc609d4aa300 287 SUPERFAMILY SSF161098 14 265 3.66E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS02440 1db4080cab15fd146094fc609d4aa300 287 Gene3D G3DSA:1.10.3720.10 15 277 2.8E-39 T 28-03-2018 A6A12_RS02440 1db4080cab15fd146094fc609d4aa300 287 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 15 273 9.9E-127 T 28-03-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 A6A12_RS02440 1db4080cab15fd146094fc609d4aa300 287 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 12 272 3.2E-102 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 A6A12_RS09805 9d580afbd062713fda7de734b0f0f523 110 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 4 100 4.5E-45 T 28-03-2018 IPR004480 Monothiol glutaredoxin-related A6A12_RS09805 9d580afbd062713fda7de734b0f0f523 110 SUPERFAMILY SSF52833 1 103 5.77E-33 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS09805 9d580afbd062713fda7de734b0f0f523 110 Pfam PF00462 Glutaredoxin 16 80 2.7E-16 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A6A12_RS09805 9d580afbd062713fda7de734b0f0f523 110 Gene3D G3DSA:3.40.30.10 1 110 2.4E-28 T 28-03-2018 A6A12_RS09805 9d580afbd062713fda7de734b0f0f523 110 PIRSF PIRSF005894 1 107 7.3E-51 T 28-03-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 A6A12_RS09085 03a8cf9b0810679678fa52a6312681cd 116 SUPERFAMILY SSF54197 2 113 1.19E-35 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 A6A12_RS09085 03a8cf9b0810679678fa52a6312681cd 116 Pfam PF01230 HIT domain 12 109 7.4E-30 T 28-03-2018 IPR001310 Histidine triad (HIT) protein A6A12_RS09085 03a8cf9b0810679678fa52a6312681cd 116 PRINTS PR00332 Histidine triad family signature 6 22 3.0E-19 T 28-03-2018 IPR001310 Histidine triad (HIT) protein A6A12_RS09085 03a8cf9b0810679678fa52a6312681cd 116 PRINTS PR00332 Histidine triad family signature 27 45 3.0E-19 T 28-03-2018 IPR001310 Histidine triad (HIT) protein A6A12_RS09085 03a8cf9b0810679678fa52a6312681cd 116 PRINTS PR00332 Histidine triad family signature 95 105 3.0E-19 T 28-03-2018 IPR001310 Histidine triad (HIT) protein A6A12_RS09085 03a8cf9b0810679678fa52a6312681cd 116 ProSitePatterns PS00892 HIT domain signature. 88 106 - T 28-03-2018 IPR019808 Histidine triad, conserved site A6A12_RS09085 03a8cf9b0810679678fa52a6312681cd 116 Gene3D G3DSA:3.30.428.10 1 111 4.0E-28 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 A6A12_RS00265 2037a8208e3006e17df6391feee160de 194 SUPERFAMILY SSF56420 28 190 1.96E-62 T 28-03-2018 IPR023635 Peptide deformylase A6A12_RS00265 2037a8208e3006e17df6391feee160de 194 Pfam PF01327 Polypeptide deformylase 29 177 2.6E-50 T 28-03-2018 IPR023635 Peptide deformylase A6A12_RS00265 2037a8208e3006e17df6391feee160de 194 PRINTS PR01576 Peptide deformylase signature 126 144 2.8E-37 T 28-03-2018 IPR023635 Peptide deformylase A6A12_RS00265 2037a8208e3006e17df6391feee160de 194 PRINTS PR01576 Peptide deformylase signature 58 87 2.8E-37 T 28-03-2018 IPR023635 Peptide deformylase A6A12_RS00265 2037a8208e3006e17df6391feee160de 194 PRINTS PR01576 Peptide deformylase signature 114 125 2.8E-37 T 28-03-2018 IPR023635 Peptide deformylase A6A12_RS00265 2037a8208e3006e17df6391feee160de 194 PRINTS PR01576 Peptide deformylase signature 145 174 2.8E-37 T 28-03-2018 IPR023635 Peptide deformylase A6A12_RS00265 2037a8208e3006e17df6391feee160de 194 Gene3D G3DSA:3.90.45.10 24 193 2.3E-61 T 28-03-2018 IPR023635 Peptide deformylase A6A12_RS00265 2037a8208e3006e17df6391feee160de 194 Hamap MF_00163 Peptide deformylase [def]. 27 187 31.02 T 28-03-2018 IPR023635 Peptide deformylase A6A12_RS00265 2037a8208e3006e17df6391feee160de 194 PIRSF PIRSF004749 11 194 1.6E-56 T 28-03-2018 IPR023635 Peptide deformylase A6A12_RS00265 2037a8208e3006e17df6391feee160de 194 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 29 185 4.2E-61 T 28-03-2018 IPR023635 Peptide deformylase A6A12_RS09580 1785fce871d60600ff4da4f0202d9e0d 441 SUPERFAMILY SSF109604 19 167 2.83E-83 T 28-03-2018 A6A12_RS09580 1785fce871d60600ff4da4f0202d9e0d 441 SUPERFAMILY SSF109604 232 438 2.83E-83 T 28-03-2018 A6A12_RS09580 1785fce871d60600ff4da4f0202d9e0d 441 Gene3D G3DSA:1.10.3550.10 260 432 2.3E-24 T 28-03-2018 IPR027432 Deoxyguanosinetriphosphate triphosphohydrolase, C-terminal domain A6A12_RS09580 1785fce871d60600ff4da4f0202d9e0d 441 Gene3D G3DSA:1.10.3210.10 2 227 6.1E-62 T 28-03-2018 A6A12_RS09580 1785fce871d60600ff4da4f0202d9e0d 441 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 5 435 34.444 T 28-03-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 A6A12_RS09580 1785fce871d60600ff4da4f0202d9e0d 441 Pfam PF13286 Phosphohydrolase-associated domain 343 433 1.2E-28 T 28-03-2018 IPR026875 Phosphohydrolase-associated domain A6A12_RS09580 1785fce871d60600ff4da4f0202d9e0d 441 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 24 436 9.5E-135 T 28-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 A6A12_RS09580 1785fce871d60600ff4da4f0202d9e0d 441 Pfam PF01966 HD domain 62 143 7.2E-7 T 28-03-2018 IPR006674 HD domain A6A12_RS09580 1785fce871d60600ff4da4f0202d9e0d 441 SMART SM00471 58 264 5.3E-8 T 28-03-2018 IPR003607 HD/PDEase domain A6A12_RS07345 421cc9493a69b3531fce24330e4a6807 463 PRINTS PR00095 Anthranilate synthase component I signature 313 326 2.6E-17 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A6A12_RS07345 421cc9493a69b3531fce24330e4a6807 463 PRINTS PR00095 Anthranilate synthase component I signature 408 422 2.6E-17 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A6A12_RS07345 421cc9493a69b3531fce24330e4a6807 463 PRINTS PR00095 Anthranilate synthase component I signature 299 312 2.6E-17 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A6A12_RS07345 421cc9493a69b3531fce24330e4a6807 463 PRINTS PR00095 Anthranilate synthase component I signature 393 407 2.6E-17 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A6A12_RS07345 421cc9493a69b3531fce24330e4a6807 463 Gene3D G3DSA:3.60.120.10 11 461 3.7E-155 T 28-03-2018 IPR005801 ADC synthase GO:0009058 A6A12_RS07345 421cc9493a69b3531fce24330e4a6807 463 SUPERFAMILY SSF56322 16 460 1.05E-143 T 28-03-2018 IPR005801 ADC synthase GO:0009058 A6A12_RS07345 421cc9493a69b3531fce24330e4a6807 463 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 116 453 4.2E-117 T 28-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 A6A12_RS07345 421cc9493a69b3531fce24330e4a6807 463 Pfam PF04715 Anthranilate synthase component I, N terminal region 29 162 4.2E-29 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A6A12_RS07345 421cc9493a69b3531fce24330e4a6807 463 Pfam PF00425 chorismate binding enzyme 197 451 1.4E-94 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 SMART SM00864 13 205 7.2E-114 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 Gene3D G3DSA:3.30.1330.20 215 325 2.6E-45 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 362 38.306 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 SUPERFAMILY SSF52490 13 208 3.79E-69 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 Pfam PF12327 FtsZ family, C-terminal domain 222 316 2.9E-36 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 Gene3D G3DSA:3.40.50.1440 9 214 5.6E-41 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 328 4.5E-136 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 SMART SM00865 207 325 8.0E-56 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 1.9E-39 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 SUPERFAMILY SSF55307 204 320 9.39E-43 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 PRINTS PR00423 Cell division protein FtsZ signature 212 233 6.0E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 PRINTS PR00423 Cell division protein FtsZ signature 126 147 6.0E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 PRINTS PR00423 Cell division protein FtsZ signature 189 211 6.0E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 PRINTS PR00423 Cell division protein FtsZ signature 98 118 6.0E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A6A12_RS11505 f4affecae5f0fd6cd3edc9103efe1dfc 405 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A6A12_RS02780 5a7d0d8747e6df3b0d63ef3395f784dc 409 Pfam PF00909 Ammonium Transporter Family 18 402 1.9E-100 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 A6A12_RS02780 5a7d0d8747e6df3b0d63ef3395f784dc 409 ProSitePatterns PS01219 Ammonium transporters signature. 163 188 - T 28-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 A6A12_RS02780 5a7d0d8747e6df3b0d63ef3395f784dc 409 TIGRFAM TIGR03644 marine_trans_1: probable ammonium transporter, marine subtype 12 405 3.6E-206 T 28-03-2018 IPR019879 Ammonium transporter, marine subtype A6A12_RS02780 5a7d0d8747e6df3b0d63ef3395f784dc 409 Gene3D G3DSA:1.10.3430.10 7 383 8.3E-107 T 28-03-2018 A6A12_RS02780 5a7d0d8747e6df3b0d63ef3395f784dc 409 SUPERFAMILY SSF111352 12 383 2.88E-106 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 A6A12_RS05585 ecb0a191fe527402b4a9f4f22ba3254c 647 Gene3D G3DSA:2.60.120.10 188 326 8.7E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS05585 ecb0a191fe527402b4a9f4f22ba3254c 647 SUPERFAMILY SSF52172 11 142 4.38E-7 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS05585 ecb0a191fe527402b4a9f4f22ba3254c 647 Gene3D G3DSA:3.40.50.2300 7 148 3.1E-9 T 28-03-2018 A6A12_RS05585 ecb0a191fe527402b4a9f4f22ba3254c 647 Gene3D G3DSA:1.10.287.130 334 478 1.4E-11 T 28-03-2018 A6A12_RS05585 ecb0a191fe527402b4a9f4f22ba3254c 647 SUPERFAMILY SSF47384 341 391 2.35E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS05585 ecb0a191fe527402b4a9f4f22ba3254c 647 SUPERFAMILY SSF55874 487 645 7.2E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS05585 ecb0a191fe527402b4a9f4f22ba3254c 647 SUPERFAMILY SSF51206 208 317 3.01E-19 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like A6A12_RS05585 ecb0a191fe527402b4a9f4f22ba3254c 647 Gene3D G3DSA:3.30.565.10 479 646 8.2E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS05585 ecb0a191fe527402b4a9f4f22ba3254c 647 Pfam PF00027 Cyclic nucleotide-binding domain 208 294 9.4E-16 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A6A12_RS05585 ecb0a191fe527402b4a9f4f22ba3254c 647 SMART SM00387 534 647 5.8E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS05585 ecb0a191fe527402b4a9f4f22ba3254c 647 PRINTS PR00344 Bacterial sensor protein C-terminal signature 631 644 1.9E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS05585 ecb0a191fe527402b4a9f4f22ba3254c 647 PRINTS PR00344 Bacterial sensor protein C-terminal signature 607 625 1.9E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS05585 ecb0a191fe527402b4a9f4f22ba3254c 647 PRINTS PR00344 Bacterial sensor protein C-terminal signature 575 589 1.9E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS05585 ecb0a191fe527402b4a9f4f22ba3254c 647 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 536 645 8.9E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS05585 ecb0a191fe527402b4a9f4f22ba3254c 647 Pfam PF00512 His Kinase A (phospho-acceptor) domain 346 382 4.4E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 SUPERFAMILY SSF47384 341 401 8.63E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 Gene3D G3DSA:1.10.287.560 340 401 1.2E-10 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 SMART SM00073 13 112 6.2E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 Gene3D G3DSA:2.30.30.40 668 714 1.7E-18 T 28-03-2018 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 Gene3D G3DSA:2.30.30.40 586 613 0.16 T 28-03-2018 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 Gene3D G3DSA:1.20.120.160 12 153 2.6E-28 T 28-03-2018 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 SUPERFAMILY SSF50341 585 714 6.15E-33 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 SMART SM01231 340 400 8.0E-14 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 Gene3D G3DSA:3.30.565.10 402 585 8.6E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 341 394 1.3E-7 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 Gene3D G3DSA:2.40.50.180 614 667 1.6E-16 T 28-03-2018 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 SMART SM00387 445 586 5.8E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 Pfam PF01584 CheW-like domain 592 717 2.5E-26 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 Pfam PF01627 Hpt domain 16 104 1.3E-15 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 SUPERFAMILY SSF55874 403 584 1.83E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 SUPERFAMILY SSF47226 13 137 3.27E-23 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 448 585 1.5E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 PRINTS PR00344 Bacterial sensor protein C-terminal signature 490 504 8.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 PRINTS PR00344 Bacterial sensor protein C-terminal signature 570 583 8.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 564 8.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 540 8.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS07420 5044bc057e8d9155e0d5dda1085de92d 731 SMART SM00260 578 715 2.3E-34 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS13475 1cf146c315198e39fa3eb44bba1621e8 251 SUPERFAMILY SSF56112 63 211 7.55E-18 T 28-03-2018 IPR011009 Protein kinase-like domain A6A12_RS13475 1cf146c315198e39fa3eb44bba1621e8 251 Gene3D G3DSA:1.10.510.10 138 227 1.2E-12 T 28-03-2018 A6A12_RS13475 1cf146c315198e39fa3eb44bba1621e8 251 Hamap MF_00521 3-deoxy-D-manno-octulosonic acid kinase [kdkA]. 19 251 41.403 T 28-03-2018 IPR022826 3-deoxy-D-manno-octulosonic acid kinase GO:0016773 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.166|MetaCyc: PWY-7675|MetaCyc: PWY-7676 A6A12_RS13475 1cf146c315198e39fa3eb44bba1621e8 251 Gene3D G3DSA:3.30.200.20 39 137 2.2E-6 T 28-03-2018 A6A12_RS13475 1cf146c315198e39fa3eb44bba1621e8 251 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 47 229 1.2E-64 T 28-03-2018 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 A6A12_RS13360 ee81f2d58f95d081b6b08123dd99ba0b 360 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 5 353 1.8E-157 T 28-03-2018 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 A6A12_RS13360 ee81f2d58f95d081b6b08123dd99ba0b 360 Gene3D G3DSA:3.40.50.720 1 207 5.7E-25 T 28-03-2018 A6A12_RS13360 ee81f2d58f95d081b6b08123dd99ba0b 360 SUPERFAMILY SSF51735 2 347 9.66E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS13360 ee81f2d58f95d081b6b08123dd99ba0b 360 Pfam PF16363 GDP-mannose 4,6 dehydratase 12 242 1.5E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS13360 ee81f2d58f95d081b6b08123dd99ba0b 360 Gene3D G3DSA:3.90.25.10 208 356 8.4E-28 T 28-03-2018 A6A12_RS10960 69378fbbc29d2817cac7d6e006edf287 365 PIRSF PIRSF006769 1 362 2.2E-116 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 A6A12_RS10960 69378fbbc29d2817cac7d6e006edf287 365 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 102 3.5E-17 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A6A12_RS10960 69378fbbc29d2817cac7d6e006edf287 365 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 149 357 5.1E-53 T 28-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 A6A12_RS10960 69378fbbc29d2817cac7d6e006edf287 365 SUPERFAMILY SSF53597 148 357 7.71E-52 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A6A12_RS10960 69378fbbc29d2817cac7d6e006edf287 365 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 91 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A6A12_RS10960 69378fbbc29d2817cac7d6e006edf287 365 Gene3D G3DSA:3.40.430.10 148 365 6.5E-54 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A6A12_RS10960 69378fbbc29d2817cac7d6e006edf287 365 SUPERFAMILY SSF53927 6 147 2.61E-44 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A6A12_RS10960 69378fbbc29d2817cac7d6e006edf287 365 Pfam PF01872 RibD C-terminal domain 150 354 1.2E-47 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 A6A12_RS10960 69378fbbc29d2817cac7d6e006edf287 365 Gene3D G3DSA:3.40.140.10 3 147 2.9E-31 T 28-03-2018 A6A12_RS10960 69378fbbc29d2817cac7d6e006edf287 365 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 10 355 1.6E-120 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 A6A12_RS13080 c2e2d003023cea1cd5e0a1eceb0b2bec 210 Gene3D G3DSA:3.30.420.10 12 201 2.4E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS13080 c2e2d003023cea1cd5e0a1eceb0b2bec 210 SUPERFAMILY SSF53098 25 198 2.23E-35 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS13080 c2e2d003023cea1cd5e0a1eceb0b2bec 210 SMART SM00479 29 202 3.6E-23 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS13080 c2e2d003023cea1cd5e0a1eceb0b2bec 210 Pfam PF00929 Exonuclease 31 193 5.1E-19 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 Gene3D G3DSA:3.90.740.10 205 511 1.7E-95 T 28-03-2018 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 15 855 6.1E-294 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 Gene3D G3DSA:3.40.50.620 42 123 3.7E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 Gene3D G3DSA:3.30.2320.20 817 910 7.9E-22 T 28-03-2018 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 Gene3D G3DSA:1.10.730.10 587 809 1.0E-45 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 2 943 21.439 T 28-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 SUPERFAMILY SSF50677 203 411 1.47E-51 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 SUPERFAMILY SSF52374 411 656 2.38E-137 T 28-03-2018 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 SUPERFAMILY SSF52374 3 202 2.38E-137 T 28-03-2018 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 SUPERFAMILY SSF47323 661 943 9.16E-74 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 Pfam PF06827 Zinc finger found in FPG and IleRS 913 940 5.2E-6 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 241 264 5.4E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 570 579 5.4E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 409 424 5.4E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 535 548 5.4E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 51 62 5.4E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 Pfam PF08264 Anticodon-binding domain of tRNA 694 856 9.4E-28 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 69 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS03195 2e3c720732dbd99c020107150137a7c5 952 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 649 3.4E-216 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS02800 a3d78e35c427c1aa82898577153ceb89 470 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 416 466 9.1E-10 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02800 a3d78e35c427c1aa82898577153ceb89 470 Gene3D G3DSA:3.40.120.10 272 382 2.5E-29 T 28-03-2018 A6A12_RS02800 a3d78e35c427c1aa82898577153ceb89 470 SUPERFAMILY SSF55957 374 466 3.14E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02800 a3d78e35c427c1aa82898577153ceb89 470 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 1.1E-11 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02800 a3d78e35c427c1aa82898577153ceb89 470 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 242 257 1.1E-11 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02800 a3d78e35c427c1aa82898577153ceb89 470 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 180 199 1.1E-11 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02800 a3d78e35c427c1aa82898577153ceb89 470 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 214 227 1.1E-11 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02800 a3d78e35c427c1aa82898577153ceb89 470 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 267 378 2.5E-24 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02800 a3d78e35c427c1aa82898577153ceb89 470 SUPERFAMILY SSF53738 2 187 3.92E-41 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02800 a3d78e35c427c1aa82898577153ceb89 470 Gene3D G3DSA:3.40.120.10 166 271 4.1E-27 T 28-03-2018 A6A12_RS02800 a3d78e35c427c1aa82898577153ceb89 470 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 162 262 4.0E-24 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02800 a3d78e35c427c1aa82898577153ceb89 470 Gene3D G3DSA:3.30.310.50 383 469 2.2E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02800 a3d78e35c427c1aa82898577153ceb89 470 SUPERFAMILY SSF53738 250 379 4.32E-29 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02800 a3d78e35c427c1aa82898577153ceb89 470 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 136 1.0E-38 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A6A12_RS02800 a3d78e35c427c1aa82898577153ceb89 470 Gene3D G3DSA:3.40.120.10 1 165 3.0E-42 T 28-03-2018 A6A12_RS03750 f73b44a0a948a2ac3300f51f0fddda72 66 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 1 52 7.4E-26 T 28-03-2018 IPR010260 DNA-binding transcriptional activator AlpA A6A12_RS03750 f73b44a0a948a2ac3300f51f0fddda72 66 Gene3D G3DSA:1.10.10.10 4 64 7.9E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03750 f73b44a0a948a2ac3300f51f0fddda72 66 SUPERFAMILY SSF46955 2 55 2.38E-5 T 28-03-2018 IPR009061 Putative DNA-binding domain A6A12_RS11200 ef536e9b85519df08e784ff6e18758a7 343 Gene3D G3DSA:3.30.60.70 131 171 2.0E-15 T 28-03-2018 A6A12_RS11200 ef536e9b85519df08e784ff6e18758a7 343 Gene3D G3DSA:2.160.10.10 172 340 5.7E-19 T 28-03-2018 A6A12_RS11200 ef536e9b85519df08e784ff6e18758a7 343 TIGRFAM TIGR03536 DapD_gpp: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 3 343 2.6E-178 T 28-03-2018 IPR019876 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, gammaproteobacteria KEGG: 00300+2.3.1.117 A6A12_RS11200 ef536e9b85519df08e784ff6e18758a7 343 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 2 340 45.966 T 28-03-2018 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 A6A12_RS11200 ef536e9b85519df08e784ff6e18758a7 343 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 253 285 6.9E-13 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS11200 ef536e9b85519df08e784ff6e18758a7 343 SUPERFAMILY SSF51161 90 324 3.19E-36 T 28-03-2018 IPR011004 Trimeric LpxA-like A6A12_RS11200 ef536e9b85519df08e784ff6e18758a7 343 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 131 171 3.3E-16 T 28-03-2018 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 A6A12_RS00295 31c7a2d3cb80e2e4c165a1b32e56ad19 161 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 156 31.908 T 28-03-2018 IPR033747 Class I PurE A6A12_RS00295 31c7a2d3cb80e2e4c165a1b32e56ad19 161 PIRSF PIRSF001338 1 160 2.6E-67 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 A6A12_RS00295 31c7a2d3cb80e2e4c165a1b32e56ad19 161 SUPERFAMILY SSF52255 2 158 1.7E-65 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A6A12_RS00295 31c7a2d3cb80e2e4c165a1b32e56ad19 161 Gene3D G3DSA:3.40.50.7700 1 160 4.1E-65 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A6A12_RS00295 31c7a2d3cb80e2e4c165a1b32e56ad19 161 Pfam PF00731 AIR carboxylase 2 150 7.0E-64 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A6A12_RS00295 31c7a2d3cb80e2e4c165a1b32e56ad19 161 SMART SM01001 1 152 7.2E-103 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A6A12_RS00295 31c7a2d3cb80e2e4c165a1b32e56ad19 161 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 157 3.5E-66 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A6A12_RS03620 7126649ff2f224fbcc4a60b9a57c5edf 419 Pfam PF01266 FAD dependent oxidoreductase 2 398 1.1E-72 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A6A12_RS03620 7126649ff2f224fbcc4a60b9a57c5edf 419 Gene3D G3DSA:3.30.9.10 212 359 3.9E-29 T 28-03-2018 A6A12_RS03620 7126649ff2f224fbcc4a60b9a57c5edf 419 SUPERFAMILY SSF54373 270 360 3.66E-18 T 28-03-2018 A6A12_RS03620 7126649ff2f224fbcc4a60b9a57c5edf 419 Gene3D G3DSA:3.40.50.720 2 88 1.4E-7 T 28-03-2018 A6A12_RS03620 7126649ff2f224fbcc4a60b9a57c5edf 419 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 411 46.522 T 28-03-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 A6A12_RS03620 7126649ff2f224fbcc4a60b9a57c5edf 419 SUPERFAMILY SSF51905 1 54 1.42E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS03620 7126649ff2f224fbcc4a60b9a57c5edf 419 SUPERFAMILY SSF51905 360 416 1.42E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS03620 7126649ff2f224fbcc4a60b9a57c5edf 419 SUPERFAMILY SSF51905 107 270 1.42E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS03620 7126649ff2f224fbcc4a60b9a57c5edf 419 Gene3D G3DSA:3.30.9.10 134 211 1.6E-8 T 28-03-2018 A6A12_RS05335 50980255f2dc90d4a30c4946efd79d85 499 SUPERFAMILY SSF50494 1 230 3.28E-57 T 28-03-2018 IPR009003 Peptidase S1, PA clan A6A12_RS05335 50980255f2dc90d4a30c4946efd79d85 499 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 177 188 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site A6A12_RS05335 50980255f2dc90d4a30c4946efd79d85 499 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 80 94 2.0E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A6A12_RS05335 50980255f2dc90d4a30c4946efd79d85 499 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 15 30 2.0E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A6A12_RS05335 50980255f2dc90d4a30c4946efd79d85 499 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 176 188 2.0E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 A6A12_RS05335 50980255f2dc90d4a30c4946efd79d85 499 Gene3D G3DSA:2.40.10.10 1 25 9.6E-10 T 28-03-2018 A6A12_RS05335 50980255f2dc90d4a30c4946efd79d85 499 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 25 30 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 A6A12_RS05335 50980255f2dc90d4a30c4946efd79d85 499 Gene3D G3DSA:2.40.10.10 26 244 4.2E-53 T 28-03-2018 A6A12_RS05335 50980255f2dc90d4a30c4946efd79d85 499 SMART SM00020 1 226 6.6E-46 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A6A12_RS05335 50980255f2dc90d4a30c4946efd79d85 499 Pfam PF00089 Trypsin 1 226 3.6E-46 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 A6A12_RS00825 b8ee49b5cb9dc010034d205f767faff7 144 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 2 144 4.4E-62 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 A6A12_RS00825 b8ee49b5cb9dc010034d205f767faff7 144 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 3 142 1.2E-50 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 A6A12_RS00825 b8ee49b5cb9dc010034d205f767faff7 144 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 144 32.437 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 A6A12_RS00825 b8ee49b5cb9dc010034d205f767faff7 144 SUPERFAMILY SSF69500 2 143 5.49E-53 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain A6A12_RS00825 b8ee49b5cb9dc010034d205f767faff7 144 Gene3D G3DSA:3.50.80.10 1 144 4.7E-50 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain A6A12_RS10870 aaead304362201593a4e9f6916115eb8 810 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 2 810 25.554 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 A6A12_RS10870 aaead304362201593a4e9f6916115eb8 810 Gene3D G3DSA:2.40.160.50 387 810 3.8E-79 T 28-03-2018 A6A12_RS10870 aaead304362201593a4e9f6916115eb8 810 Pfam PF01103 Surface antigen 448 810 6.4E-87 T 28-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 A6A12_RS10870 aaead304362201593a4e9f6916115eb8 810 Gene3D G3DSA:3.10.20.310 174 265 8.8E-21 T 28-03-2018 A6A12_RS10870 aaead304362201593a4e9f6916115eb8 810 Gene3D G3DSA:3.10.20.310 92 173 1.0E-12 T 28-03-2018 A6A12_RS10870 aaead304362201593a4e9f6916115eb8 810 PIRSF PIRSF006076 1 810 9.2E-244 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 A6A12_RS10870 aaead304362201593a4e9f6916115eb8 810 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 24 810 2.7E-276 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 A6A12_RS10870 aaead304362201593a4e9f6916115eb8 810 Gene3D G3DSA:3.10.20.310 266 346 2.0E-8 T 28-03-2018 A6A12_RS10870 aaead304362201593a4e9f6916115eb8 810 Gene3D G3DSA:3.10.20.310 350 386 0.0082 T 28-03-2018 A6A12_RS10870 aaead304362201593a4e9f6916115eb8 810 Pfam PF07244 Surface antigen variable number repeat 92 172 1.4E-10 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 A6A12_RS10870 aaead304362201593a4e9f6916115eb8 810 Pfam PF07244 Surface antigen variable number repeat 176 263 1.3E-15 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 A6A12_RS10870 aaead304362201593a4e9f6916115eb8 810 Pfam PF07244 Surface antigen variable number repeat 266 344 3.8E-9 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 A6A12_RS10870 aaead304362201593a4e9f6916115eb8 810 Pfam PF07244 Surface antigen variable number repeat 347 420 7.7E-16 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 A6A12_RS10870 aaead304362201593a4e9f6916115eb8 810 Gene3D G3DSA:3.10.20.310 18 91 1.4E-7 T 28-03-2018 A6A12_RS02630 f236a4cb19182c2df69625e8cb5e0294 302 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 10 302 56.052 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD A6A12_RS02630 f236a4cb19182c2df69625e8cb5e0294 302 SUPERFAMILY SSF47823 8 104 4.32E-36 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal A6A12_RS02630 f236a4cb19182c2df69625e8cb5e0294 302 SUPERFAMILY SSF56349 110 300 3.83E-56 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS02630 f236a4cb19182c2df69625e8cb5e0294 302 Gene3D G3DSA:1.10.150.130 8 115 4.3E-23 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A6A12_RS02630 f236a4cb19182c2df69625e8cb5e0294 302 Pfam PF00589 Phage integrase family 117 288 4.3E-54 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS02630 f236a4cb19182c2df69625e8cb5e0294 302 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 13 302 7.5E-117 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 A6A12_RS02630 f236a4cb19182c2df69625e8cb5e0294 302 Gene3D G3DSA:1.10.443.10 116 296 4.2E-48 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS02630 f236a4cb19182c2df69625e8cb5e0294 302 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 12 94 3.9E-20 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A6A12_RS02630 f236a4cb19182c2df69625e8cb5e0294 302 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 8 302 61.831 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 A6A12_RS11265 03b73214262cdb92aedab474344e6a68 562 SUPERFAMILY SSF56801 18 548 1.01E-111 T 28-03-2018 A6A12_RS11265 03b73214262cdb92aedab474344e6a68 562 Gene3D G3DSA:2.30.38.10 362 434 7.7E-19 T 28-03-2018 A6A12_RS11265 03b73214262cdb92aedab474344e6a68 562 Gene3D G3DSA:3.40.50.980 17 187 4.2E-33 T 28-03-2018 A6A12_RS11265 03b73214262cdb92aedab474344e6a68 562 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 28-03-2018 IPR020845 AMP-binding, conserved site A6A12_RS11265 03b73214262cdb92aedab474344e6a68 562 Gene3D G3DSA:3.40.50.980 188 361 4.0E-35 T 28-03-2018 A6A12_RS11265 03b73214262cdb92aedab474344e6a68 562 Pfam PF00501 AMP-binding enzyme 24 441 3.7E-88 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A6A12_RS11265 03b73214262cdb92aedab474344e6a68 562 Gene3D G3DSA:3.30.300.30 436 552 1.6E-10 T 28-03-2018 A6A12_RS05115 17f92b51b992561fd3e9a425b1aab8b3 412 SMART SM00487 20 221 2.1E-64 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS05115 17f92b51b992561fd3e9a425b1aab8b3 412 Pfam PF00271 Helicase conserved C-terminal domain 232 338 6.2E-27 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS05115 17f92b51b992561fd3e9a425b1aab8b3 412 Gene3D G3DSA:3.40.50.300 1 225 2.8E-61 T 28-03-2018 A6A12_RS05115 17f92b51b992561fd3e9a425b1aab8b3 412 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A6A12_RS05115 17f92b51b992561fd3e9a425b1aab8b3 412 SUPERFAMILY SSF52540 73 359 3.52E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05115 17f92b51b992561fd3e9a425b1aab8b3 412 Gene3D G3DSA:3.40.50.300 226 381 2.5E-42 T 28-03-2018 A6A12_RS05115 17f92b51b992561fd3e9a425b1aab8b3 412 Pfam PF00270 DEAD/DEAH box helicase 25 194 2.1E-52 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A6A12_RS05115 17f92b51b992561fd3e9a425b1aab8b3 412 SMART SM00490 257 338 1.9E-31 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS06895 64c3694b5c6e1c4ad34ea424dda382f1 288 Gene3D G3DSA:3.30.1490.70 147 195 3.7E-10 T 28-03-2018 A6A12_RS06895 64c3694b5c6e1c4ad34ea424dda382f1 288 Gene3D G3DSA:3.30.470.30 59 146 9.7E-15 T 28-03-2018 A6A12_RS06895 64c3694b5c6e1c4ad34ea424dda382f1 288 SUPERFAMILY SSF56091 29 206 2.5E-34 T 28-03-2018 A6A12_RS06895 64c3694b5c6e1c4ad34ea424dda382f1 288 Pfam PF14743 DNA ligase OB-like domain 221 285 2.6E-27 T 28-03-2018 IPR029319 DNA ligase, OB-like domain A6A12_RS06895 64c3694b5c6e1c4ad34ea424dda382f1 288 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 183 206 - T 28-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A6A12_RS06895 64c3694b5c6e1c4ad34ea424dda382f1 288 Gene3D G3DSA:2.40.50.140 196 287 2.7E-23 T 28-03-2018 A6A12_RS06895 64c3694b5c6e1c4ad34ea424dda382f1 288 SUPERFAMILY SSF50249 181 285 1.77E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 PIRSF PIRSF000350 2 449 5.5E-83 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 SUPERFAMILY SSF51905 4 370 6.26E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 43 53 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 TIGRFAM TIGR01421 gluta_reduc_1: glutathione-disulfide reductase 8 454 6.0E-210 T 28-03-2018 IPR006322 Glutathione reductase, eukaryote/bacterial GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081|Reactome: R-HSA-2408550|Reactome: R-HSA-3299685|Reactome: R-HSA-499943|Reactome: R-HSA-5628897 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 Gene3D G3DSA:3.50.50.60 5 168 1.0E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 Gene3D G3DSA:3.40.50.720 169 328 2.0E-34 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 344 453 1.7E-32 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 SUPERFAMILY SSF55424 341 454 2.75E-34 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 Gene3D G3DSA:3.30.390.30 329 454 5.5E-36 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 148 1.1E-63 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 1.1E-63 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 1.1E-63 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 309 1.1E-63 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 429 449 1.1E-63 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 1.1E-63 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 1.1E-63 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 1.1E-63 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 340 361 1.1E-63 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 5.7E-29 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 5.7E-29 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 5.7E-29 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 309 5.7E-29 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 5.7E-29 T 28-03-2018 A6A12_RS13795 c3a9338ba47ba2a1ee466bcc8f36c5c6 454 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 323 4.6E-69 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS02825 5187320237e2a07b21bb88549b3982b4 330 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS02825 5187320237e2a07b21bb88549b3982b4 330 SUPERFAMILY SSF52540 10 262 7.19E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS02825 5187320237e2a07b21bb88549b3982b4 330 SMART SM00382 43 241 4.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS02825 5187320237e2a07b21bb88549b3982b4 330 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 308 7.5E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A6A12_RS02825 5187320237e2a07b21bb88549b3982b4 330 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 328 1.3E-24 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A6A12_RS02825 5187320237e2a07b21bb88549b3982b4 330 Gene3D G3DSA:3.40.50.300 7 330 2.0E-62 T 28-03-2018 A6A12_RS02825 5187320237e2a07b21bb88549b3982b4 330 Pfam PF00005 ABC transporter 35 192 2.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS00610 92750bd2ca79d7c5e9e65e0be136eca8 213 Gene3D G3DSA:1.10.357.10 10 209 2.5E-24 T 28-03-2018 A6A12_RS00610 92750bd2ca79d7c5e9e65e0be136eca8 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 61 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A6A12_RS00610 92750bd2ca79d7c5e9e65e0be136eca8 213 SUPERFAMILY SSF46689 5 80 3.07E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS00610 92750bd2ca79d7c5e9e65e0be136eca8 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 61 1.3E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A6A12_RS06105 47e4dc243a306cacc7aee1733665a505 458 PIRSF PIRSF006603 8 458 5.9E-66 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS06105 47e4dc243a306cacc7aee1733665a505 458 Pfam PF01554 MatE 252 413 1.0E-17 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS06105 47e4dc243a306cacc7aee1733665a505 458 Pfam PF01554 MatE 25 185 4.6E-26 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS06105 47e4dc243a306cacc7aee1733665a505 458 TIGRFAM TIGR00797 matE: MATE efflux family protein 25 421 1.5E-61 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS11745 f0aa410f1cb4ab60917e51c7db2e015d 403 SUPERFAMILY SSF81891 120 400 1.09E-55 T 28-03-2018 A6A12_RS11745 f0aa410f1cb4ab60917e51c7db2e015d 403 Hamap MF_01262 CCA-adding enzyme [cca]. 1 401 43.295 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 A6A12_RS11745 f0aa410f1cb4ab60917e51c7db2e015d 403 Hamap MF_01261 Multifunctional CCA protein [cca]. 1 403 52.71 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 A6A12_RS11745 f0aa410f1cb4ab60917e51c7db2e015d 403 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 149 212 6.5E-15 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A6A12_RS11745 f0aa410f1cb4ab60917e51c7db2e015d 403 Pfam PF01743 Poly A polymerase head domain 3 122 7.9E-18 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A6A12_RS11745 f0aa410f1cb4ab60917e51c7db2e015d 403 PIRSF PIRSF000813 1 403 3.5E-201 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 A6A12_RS11745 f0aa410f1cb4ab60917e51c7db2e015d 403 Pfam PF01966 HD domain 231 328 1.9E-8 T 28-03-2018 IPR006674 HD domain A6A12_RS11745 f0aa410f1cb4ab60917e51c7db2e015d 403 SUPERFAMILY SSF81301 2 119 4.14E-31 T 28-03-2018 A6A12_RS11745 f0aa410f1cb4ab60917e51c7db2e015d 403 Gene3D G3DSA:3.30.460.10 1 118 2.6E-28 T 28-03-2018 A6A12_RS11745 f0aa410f1cb4ab60917e51c7db2e015d 403 Gene3D G3DSA:1.10.3090.10 119 402 1.3E-59 T 28-03-2018 A6A12_RS04770 e3fa3a6fa52cb6acf301b60cea1aa020 170 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 12 152 2.3E-36 T 28-03-2018 IPR001453 MoaB/Mog domain A6A12_RS04770 e3fa3a6fa52cb6acf301b60cea1aa020 170 SUPERFAMILY SSF53218 6 168 1.83E-46 T 28-03-2018 IPR001453 MoaB/Mog domain A6A12_RS04770 e3fa3a6fa52cb6acf301b60cea1aa020 170 PIRSF PIRSF006443 1 166 2.1E-65 T 28-03-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 A6A12_RS04770 e3fa3a6fa52cb6acf301b60cea1aa020 170 Pfam PF00994 Probable molybdopterin binding domain 14 156 2.4E-34 T 28-03-2018 IPR001453 MoaB/Mog domain A6A12_RS04770 e3fa3a6fa52cb6acf301b60cea1aa020 170 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 72 85 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 A6A12_RS04770 e3fa3a6fa52cb6acf301b60cea1aa020 170 Gene3D G3DSA:3.40.980.10 3 170 2.9E-34 T 28-03-2018 IPR001453 MoaB/Mog domain A6A12_RS04770 e3fa3a6fa52cb6acf301b60cea1aa020 170 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 8 168 4.4E-84 T 28-03-2018 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 A6A12_RS04770 e3fa3a6fa52cb6acf301b60cea1aa020 170 SMART SM00852 14 158 2.6E-28 T 28-03-2018 IPR001453 MoaB/Mog domain A6A12_RS09715 dc44c3f8da39b9118eed4e979c578bb1 194 Hamap MF_00528 Septum formation protein Maf [maf]. 5 192 29.384 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 A6A12_RS09715 dc44c3f8da39b9118eed4e979c578bb1 194 SUPERFAMILY SSF52972 1 186 5.04E-58 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A6A12_RS09715 dc44c3f8da39b9118eed4e979c578bb1 194 Gene3D G3DSA:3.90.950.10 4 194 2.3E-55 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A6A12_RS09715 dc44c3f8da39b9118eed4e979c578bb1 194 PIRSF PIRSF006305 1 193 5.4E-47 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 A6A12_RS09715 dc44c3f8da39b9118eed4e979c578bb1 194 TIGRFAM TIGR00172 maf: septum formation protein Maf 4 185 4.9E-52 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 A6A12_RS09715 dc44c3f8da39b9118eed4e979c578bb1 194 Pfam PF02545 Maf-like protein 5 187 3.2E-46 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 A6A12_RS08105 90b4d6aa98932a100aea2b8894290217 924 SMART SM00052 662 912 2.2E-94 T 28-03-2018 IPR001633 EAL domain A6A12_RS08105 90b4d6aa98932a100aea2b8894290217 924 Pfam PF00563 EAL domain 668 907 6.8E-70 T 28-03-2018 IPR001633 EAL domain A6A12_RS08105 90b4d6aa98932a100aea2b8894290217 924 SMART SM00267 482 649 8.7E-4 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS08105 90b4d6aa98932a100aea2b8894290217 924 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 368 487 4.2E-10 T 28-03-2018 IPR000014 PAS domain A6A12_RS08105 90b4d6aa98932a100aea2b8894290217 924 Pfam PF13426 PAS domain 383 481 3.1E-8 T 28-03-2018 IPR000014 PAS domain A6A12_RS08105 90b4d6aa98932a100aea2b8894290217 924 SUPERFAMILY SSF55073 499 650 4.71E-11 T 28-03-2018 IPR029787 Nucleotide cyclase A6A12_RS08105 90b4d6aa98932a100aea2b8894290217 924 Gene3D G3DSA:3.30.70.270 485 651 2.4E-17 T 28-03-2018 A6A12_RS08105 90b4d6aa98932a100aea2b8894290217 924 Pfam PF00990 Diguanylate cyclase, GGDEF domain 494 632 8.6E-8 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS08105 90b4d6aa98932a100aea2b8894290217 924 Pfam PF05228 CHASE4 domain 72 226 1.2E-30 T 28-03-2018 IPR007892 CHASE4 A6A12_RS08105 90b4d6aa98932a100aea2b8894290217 924 SUPERFAMILY SSF55785 361 480 6.63E-12 T 28-03-2018 IPR000014 PAS domain A6A12_RS08105 90b4d6aa98932a100aea2b8894290217 924 SUPERFAMILY SSF141868 668 917 1.29E-77 T 28-03-2018 IPR001633 EAL domain A6A12_RS08105 90b4d6aa98932a100aea2b8894290217 924 Gene3D G3DSA:3.20.20.450 652 922 5.4E-83 T 28-03-2018 IPR001633 EAL domain A6A12_RS08105 90b4d6aa98932a100aea2b8894290217 924 Gene3D G3DSA:3.30.450.20 357 484 8.9E-15 T 28-03-2018 A6A12_RS11925 1425339c8a3cceba43e2d7d6d7e9bfa4 355 Pfam PF13528 Glycosyl transferase family 1 9 307 1.1E-36 T 28-03-2018 A6A12_RS11925 1425339c8a3cceba43e2d7d6d7e9bfa4 355 Gene3D G3DSA:3.40.50.2000 3 326 3.6E-10 T 28-03-2018 A6A12_RS11925 1425339c8a3cceba43e2d7d6d7e9bfa4 355 TIGRFAM TIGR00661 MJ1255: conserved hypothetical protein 9 317 1.2E-109 T 28-03-2018 IPR005262 Conserved hypothetical protein CHP00661 A6A12_RS11925 1425339c8a3cceba43e2d7d6d7e9bfa4 355 SUPERFAMILY SSF53756 18 307 3.49E-10 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 520 3.2E-229 T 28-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 PRINTS PR00681 Ribosomal protein S1 signature 21 39 4.8E-97 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 PRINTS PR00681 Ribosomal protein S1 signature 155 175 4.8E-97 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 PRINTS PR00681 Ribosomal protein S1 signature 330 348 4.8E-97 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 PRINTS PR00681 Ribosomal protein S1 signature 126 143 4.8E-97 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 PRINTS PR00681 Ribosomal protein S1 signature 108 124 4.8E-97 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 PRINTS PR00681 Ribosomal protein S1 signature 212 233 4.8E-97 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 PRINTS PR00681 Ribosomal protein S1 signature 290 309 4.8E-97 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 PRINTS PR00681 Ribosomal protein S1 signature 39 53 4.8E-97 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 PRINTS PR00681 Ribosomal protein S1 signature 84 103 4.8E-97 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 SUPERFAMILY SSF50249 88 174 1.79E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 Gene3D G3DSA:2.40.50.140 1 92 1.4E-7 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 PIRSF PIRSF002111 1 534 5.8E-217 T 28-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 Gene3D G3DSA:2.40.50.140 274 348 3.6E-27 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 Gene3D G3DSA:2.40.50.140 361 435 1.7E-20 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 SUPERFAMILY SSF50249 429 538 2.01E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 Gene3D G3DSA:2.40.50.140 441 526 1.6E-18 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 Gene3D G3DSA:2.40.50.140 95 177 2.6E-6 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 Gene3D G3DSA:2.40.50.140 183 266 7.2E-25 T 28-03-2018 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 SUPERFAMILY SSF50249 4 112 8.58E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 SUPERFAMILY SSF50249 190 277 2.09E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 SUPERFAMILY SSF50249 255 364 2.5E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 SUPERFAMILY SSF50249 342 440 3.36E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 Pfam PF00575 S1 RNA binding domain 18 86 5.7E-7 T 28-03-2018 IPR003029 S1 domain GO:0003676 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 Pfam PF00575 S1 RNA binding domain 449 520 3.4E-15 T 28-03-2018 IPR003029 S1 domain GO:0003676 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 Pfam PF00575 S1 RNA binding domain 189 260 1.9E-21 T 28-03-2018 IPR003029 S1 domain GO:0003676 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 Pfam PF00575 S1 RNA binding domain 103 171 1.3E-8 T 28-03-2018 IPR003029 S1 domain GO:0003676 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 Pfam PF00575 S1 RNA binding domain 275 347 7.9E-21 T 28-03-2018 IPR003029 S1 domain GO:0003676 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 Pfam PF00575 S1 RNA binding domain 362 434 1.5E-20 T 28-03-2018 IPR003029 S1 domain GO:0003676 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 SMART SM00316 190 260 1.2E-27 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 SMART SM00316 362 434 8.8E-21 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 SMART SM00316 19 87 9.9E-4 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 SMART SM00316 103 171 3.6E-8 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 SMART SM00316 275 347 8.3E-27 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS05225 069bfcfcb726da557629d505d49febda 556 SMART SM00316 449 520 4.0E-20 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS13925 58abddea92c731999228e8a2d7009c95 298 Pfam PF00072 Response regulator receiver domain 3 115 1.0E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS13925 58abddea92c731999228e8a2d7009c95 298 Gene3D G3DSA:3.40.50.2300 1 257 7.2E-36 T 28-03-2018 A6A12_RS13925 58abddea92c731999228e8a2d7009c95 298 SMART SM00448 1 115 2.2E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS13925 58abddea92c731999228e8a2d7009c95 298 SUPERFAMILY SSF52172 2 120 4.7E-32 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS12135 39c9031b341b8b0f10198f6daa48e854 324 Pfam PF01380 SIS domain 44 173 1.1E-31 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A6A12_RS12135 39c9031b341b8b0f10198f6daa48e854 324 SUPERFAMILY SSF53697 8 319 1.76E-68 T 28-03-2018 A6A12_RS12135 39c9031b341b8b0f10198f6daa48e854 324 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 46 314 2.1E-111 T 28-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 A6A12_RS12135 39c9031b341b8b0f10198f6daa48e854 324 PIRSF PIRSF004692 1 324 6.9E-129 T 28-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 A6A12_RS12135 39c9031b341b8b0f10198f6daa48e854 324 Gene3D G3DSA:3.10.580.10 201 322 1.3E-21 T 28-03-2018 A6A12_RS12135 39c9031b341b8b0f10198f6daa48e854 324 SMART SM00116 276 323 5.7 T 28-03-2018 IPR000644 CBS domain A6A12_RS12135 39c9031b341b8b0f10198f6daa48e854 324 SMART SM00116 211 259 0.0011 T 28-03-2018 IPR000644 CBS domain A6A12_RS12135 39c9031b341b8b0f10198f6daa48e854 324 Pfam PF00571 CBS domain 211 259 8.0E-6 T 28-03-2018 IPR000644 CBS domain A6A12_RS12135 39c9031b341b8b0f10198f6daa48e854 324 Pfam PF00571 CBS domain 269 321 1.8E-5 T 28-03-2018 IPR000644 CBS domain A6A12_RS12135 39c9031b341b8b0f10198f6daa48e854 324 Gene3D G3DSA:3.40.50.10490 1 200 4.0E-57 T 28-03-2018 A6A12_RS11460 84be888329272c2e33caa3e13f64af4d 290 Gene3D G3DSA:1.10.10.10 1 78 1.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS11460 84be888329272c2e33caa3e13f64af4d 290 SUPERFAMILY SSF53850 90 280 8.14E-17 T 28-03-2018 A6A12_RS11460 84be888329272c2e33caa3e13f64af4d 290 Pfam PF03466 LysR substrate binding domain 91 277 1.9E-14 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS11460 84be888329272c2e33caa3e13f64af4d 290 SUPERFAMILY SSF46785 4 78 7.92E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS11460 84be888329272c2e33caa3e13f64af4d 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 8.8E-12 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS11460 84be888329272c2e33caa3e13f64af4d 290 Gene3D G3DSA:3.40.190.10 88 283 1.4E-5 T 28-03-2018 A6A12_RS02555 46dbbe6f4efd00e52a15d0f313552182 460 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 3.3E-21 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A6A12_RS02555 46dbbe6f4efd00e52a15d0f313552182 460 Gene3D G3DSA:1.10.260.30 328 432 1.2E-37 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A6A12_RS02555 46dbbe6f4efd00e52a15d0f313552182 460 SUPERFAMILY SSF47446 298 430 2.09E-45 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A6A12_RS02555 46dbbe6f4efd00e52a15d0f313552182 460 SMART SM00963 1 86 4.1E-35 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A6A12_RS02555 46dbbe6f4efd00e52a15d0f313552182 460 Gene3D G3DSA:1.20.120.140 1 91 1.4E-28 T 28-03-2018 A6A12_RS02555 46dbbe6f4efd00e52a15d0f313552182 460 SMART SM00962 100 296 4.2E-115 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A6A12_RS02555 46dbbe6f4efd00e52a15d0f313552182 460 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A6A12_RS02555 46dbbe6f4efd00e52a15d0f313552182 460 SUPERFAMILY SSF52540 42 352 9.21E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS02555 46dbbe6f4efd00e52a15d0f313552182 460 SMART SM00382 99 247 3.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS02555 46dbbe6f4efd00e52a15d0f313552182 460 Pfam PF00448 SRP54-type protein, GTPase domain 100 296 2.3E-74 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A6A12_RS02555 46dbbe6f4efd00e52a15d0f313552182 460 Pfam PF02978 Signal peptide binding domain 329 427 4.7E-33 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A6A12_RS02555 46dbbe6f4efd00e52a15d0f313552182 460 Gene3D G3DSA:3.40.50.300 99 210 6.4E-17 T 28-03-2018 A6A12_RS02555 46dbbe6f4efd00e52a15d0f313552182 460 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 453 33.866 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 A6A12_RS02555 46dbbe6f4efd00e52a15d0f313552182 460 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 3.1E-177 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 A6A12_RS02555 46dbbe6f4efd00e52a15d0f313552182 460 Gene3D G3DSA:1.20.120.140 211 310 1.7E-32 T 28-03-2018 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 Gene3D G3DSA:3.10.20.30 1 93 2.9E-12 T 28-03-2018 IPR012675 Beta-grasp domain A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 Gene3D G3DSA:2.40.30.10 94 179 5.3E-22 T 28-03-2018 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 PRINTS PR00410 Phenol hydroxylase reductase family signature 197 216 3.5E-25 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 PRINTS PR00410 Phenol hydroxylase reductase family signature 182 191 3.5E-25 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 PRINTS PR00410 Phenol hydroxylase reductase family signature 123 135 3.5E-25 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 PRINTS PR00410 Phenol hydroxylase reductase family signature 222 231 3.5E-25 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 PRINTS PR00410 Phenol hydroxylase reductase family signature 138 145 3.5E-25 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 PRINTS PR00410 Phenol hydroxylase reductase family signature 287 295 3.5E-25 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 72 1.1E-8 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 SUPERFAMILY SSF54292 3 89 1.84E-17 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 SUPERFAMILY SSF52343 190 321 1.83E-29 T 28-03-2018 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 35 43 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 138 145 3.7E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 197 216 3.7E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 222 231 3.7E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 287 295 3.7E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 Gene3D G3DSA:3.40.50.80 180 316 6.8E-26 T 28-03-2018 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 Pfam PF00970 Oxidoreductase FAD-binding domain 96 187 1.4E-21 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 Pfam PF00175 Oxidoreductase NAD-binding domain 198 301 1.2E-20 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A6A12_RS13370 87a1b51c98bf57139a931b74b64206f7 323 SUPERFAMILY SSF63380 93 188 1.6E-23 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A6A12_RS12415 84ce8c61d575a65c708ff6e7bc770eb4 58 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 1.3E-26 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12415 84ce8c61d575a65c708ff6e7bc770eb4 58 SUPERFAMILY SSF55129 1 58 2.35E-23 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A6A12_RS12415 84ce8c61d575a65c708ff6e7bc770eb4 58 PIRSF PIRSF002211 1 58 1.2E-28 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12415 84ce8c61d575a65c708ff6e7bc770eb4 58 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 28-03-2018 IPR018038 Ribosomal protein L30, conserved site A6A12_RS12415 84ce8c61d575a65c708ff6e7bc770eb4 58 Gene3D G3DSA:3.30.1390.20 4 58 4.7E-26 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A6A12_RS12415 84ce8c61d575a65c708ff6e7bc770eb4 58 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 22.117 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12415 84ce8c61d575a65c708ff6e7bc770eb4 58 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 5.0E-21 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A6A12_RS11865 4077e81c1f6c21361af86377d9670f5e 409 SUPERFAMILY SSF51905 268 385 1.11E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS11865 4077e81c1f6c21361af86377d9670f5e 409 SUPERFAMILY SSF51905 5 177 1.11E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS11865 4077e81c1f6c21361af86377d9670f5e 409 Pfam PF01494 FAD binding domain 5 346 4.0E-29 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 A6A12_RS11865 4077e81c1f6c21361af86377d9670f5e 409 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 295 308 - T 28-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 A6A12_RS11865 4077e81c1f6c21361af86377d9670f5e 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 4.1E-20 T 28-03-2018 A6A12_RS11865 4077e81c1f6c21361af86377d9670f5e 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 4.1E-20 T 28-03-2018 A6A12_RS11865 4077e81c1f6c21361af86377d9670f5e 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 4.1E-20 T 28-03-2018 A6A12_RS11865 4077e81c1f6c21361af86377d9670f5e 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 4.1E-20 T 28-03-2018 A6A12_RS11865 4077e81c1f6c21361af86377d9670f5e 409 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 6 391 3.1E-135 T 28-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 A6A12_RS11865 4077e81c1f6c21361af86377d9670f5e 409 Gene3D G3DSA:3.50.50.60 2 365 1.7E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS07530 f40be4012a5de4f3f362bc16a15f2811 716 Gene3D G3DSA:2.40.170.20 164 716 3.2E-71 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A6A12_RS07530 f40be4012a5de4f3f362bc16a15f2811 716 SUPERFAMILY SSF56935 30 716 3.97E-116 T 28-03-2018 A6A12_RS07530 f40be4012a5de4f3f362bc16a15f2811 716 Pfam PF00593 TonB dependent receptor 238 714 1.0E-57 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A6A12_RS07530 f40be4012a5de4f3f362bc16a15f2811 716 TIGRFAM TIGR01785 TonB-hemin: TonB-dependent heme/hemoglobin receptor family protein 27 716 2.4E-152 T 28-03-2018 IPR011276 TonB-dependent haem/haemoglobin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 A6A12_RS07530 f40be4012a5de4f3f362bc16a15f2811 716 Gene3D G3DSA:2.170.130.10 18 163 9.0E-33 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 A6A12_RS07530 f40be4012a5de4f3f362bc16a15f2811 716 Pfam PF07715 TonB-dependent Receptor Plug Domain 42 152 1.5E-26 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 A6A12_RS07530 f40be4012a5de4f3f362bc16a15f2811 716 TIGRFAM TIGR01786 TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein 28 716 1.0E-162 T 28-03-2018 IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 A6A12_RS07530 f40be4012a5de4f3f362bc16a15f2811 716 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 699 716 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site A6A12_RS12655 5e4ab91285bec3fb5e2d9531cef4d49d 228 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 83 194 1.6E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A6A12_RS12655 5e4ab91285bec3fb5e2d9531cef4d49d 228 Gene3D G3DSA:3.40.50.1000 85 227 2.5E-36 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS12655 5e4ab91285bec3fb5e2d9531cef4d49d 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 3.0E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A6A12_RS12655 5e4ab91285bec3fb5e2d9531cef4d49d 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 3.0E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A6A12_RS12655 5e4ab91285bec3fb5e2d9531cef4d49d 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 139 155 3.0E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A6A12_RS12655 5e4ab91285bec3fb5e2d9531cef4d49d 228 Gene3D G3DSA:3.40.50.1000 3 32 0.0062 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS12655 5e4ab91285bec3fb5e2d9531cef4d49d 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 193 7.3E-39 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS12655 5e4ab91285bec3fb5e2d9531cef4d49d 228 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 90 192 8.1E-14 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A6A12_RS12655 5e4ab91285bec3fb5e2d9531cef4d49d 228 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 100 189 3.6E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A6A12_RS12655 5e4ab91285bec3fb5e2d9531cef4d49d 228 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 9 224 1.3E-56 T 28-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 A6A12_RS12655 5e4ab91285bec3fb5e2d9531cef4d49d 228 Gene3D G3DSA:1.10.150.240 33 84 2.1E-15 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 A6A12_RS12655 5e4ab91285bec3fb5e2d9531cef4d49d 228 SUPERFAMILY SSF56784 5 224 2.1E-58 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS12655 5e4ab91285bec3fb5e2d9531cef4d49d 228 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 6 225 34.189 T 28-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 A6A12_RS05825 d37fde60608ad551643b8bbfcca105d4 544 Pfam PF05925 Enterobacterial virulence protein IpgD 125 542 7.9E-120 T 28-03-2018 IPR008108 Phosphatase IpgD/SopB GO:0009405|GO:0016791 A6A12_RS14125 e82e04a778fa6a63388bcdb518100c33 500 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 1 304 7.0E-142 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 A6A12_RS14125 e82e04a778fa6a63388bcdb518100c33 500 Pfam PF02610 L-arabinose isomerase 5 358 3.7E-168 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 A6A12_RS14125 e82e04a778fa6a63388bcdb518100c33 500 PIRSF PIRSF001478 1 498 2.6E-240 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 A6A12_RS14125 e82e04a778fa6a63388bcdb518100c33 500 Pfam PF11762 L-arabinose isomerase C-terminal domain 361 474 1.1E-48 T 28-03-2018 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 A6A12_RS14125 e82e04a778fa6a63388bcdb518100c33 500 SUPERFAMILY SSF50443 329 496 2.88E-67 T 28-03-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal A6A12_RS14125 e82e04a778fa6a63388bcdb518100c33 500 Hamap MF_00519 L-arabinose isomerase [araA]. 1 475 62.249 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 A6A12_RS14125 e82e04a778fa6a63388bcdb518100c33 500 SUPERFAMILY SSF53743 1 325 6.02E-120 T 28-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 A6A12_RS08385 5eca6a0fddf4456aed75bba707418d17 248 Pfam PF05100 Phage minor tail protein L 52 245 1.7E-72 T 28-03-2018 IPR006487 Bacteriophage lambda, GpL, minor tail A6A12_RS08385 5eca6a0fddf4456aed75bba707418d17 248 TIGRFAM TIGR01600 phage_tail_L: phage minor tail protein L 6 244 6.6E-58 T 28-03-2018 IPR006487 Bacteriophage lambda, GpL, minor tail A6A12_RS07255 d03f0cb44eacabbc1070fcd21402345a 815 SUPERFAMILY SSF53706 44 667 1.07E-160 T 28-03-2018 A6A12_RS07255 d03f0cb44eacabbc1070fcd21402345a 815 Gene3D G3DSA:3.40.228.10 180 450 9.0E-58 T 28-03-2018 A6A12_RS07255 d03f0cb44eacabbc1070fcd21402345a 815 Gene3D G3DSA:3.40.228.10 576 658 5.9E-9 T 28-03-2018 A6A12_RS07255 d03f0cb44eacabbc1070fcd21402345a 815 Pfam PF00384 Molybdopterin oxidoreductase 86 555 5.3E-104 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A6A12_RS07255 d03f0cb44eacabbc1070fcd21402345a 815 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 32 8.4E-5 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal A6A12_RS07255 d03f0cb44eacabbc1070fcd21402345a 815 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 498 515 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A6A12_RS07255 d03f0cb44eacabbc1070fcd21402345a 815 Pfam PF01568 Molydopterin dinucleotide binding domain 675 788 3.9E-24 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A6A12_RS07255 d03f0cb44eacabbc1070fcd21402345a 815 TIGRFAM TIGR00509 bisC_fam: molybdopterin guanine dinucleotide-containing S/N-oxide reductases 43 813 0.0 T 28-03-2018 IPR006658 Molybdopterin guanine dinucleotide-containing S/N-oxide reductase GO:0016491|GO:0055114 A6A12_RS07255 d03f0cb44eacabbc1070fcd21402345a 815 Gene3D G3DSA:3.90.55.10 37 123 1.2E-12 T 28-03-2018 A6A12_RS07255 d03f0cb44eacabbc1070fcd21402345a 815 SUPERFAMILY SSF50692 671 813 4.75E-40 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain A6A12_RS07255 d03f0cb44eacabbc1070fcd21402345a 815 Gene3D G3DSA:3.40.228.10 451 557 6.5E-8 T 28-03-2018 A6A12_RS07255 d03f0cb44eacabbc1070fcd21402345a 815 Gene3D G3DSA:2.40.40.20 659 809 1.3E-32 T 28-03-2018 A6A12_RS08380 b243e0a597236cf699019f5664d9f748 248 Pfam PF14464 Prokaryotic homologs of the JAB domain 8 92 3.5E-12 T 28-03-2018 IPR028090 JAB domain, prokaryotic A6A12_RS08380 b243e0a597236cf699019f5664d9f748 248 Gene3D G3DSA:3.40.140.10 3 120 6.0E-13 T 28-03-2018 A6A12_RS08380 b243e0a597236cf699019f5664d9f748 248 SUPERFAMILY SSF54001 120 246 4.66E-14 T 28-03-2018 A6A12_RS08380 b243e0a597236cf699019f5664d9f748 248 Gene3D G3DSA:3.90.1720.10 187 248 1.7E-4 T 28-03-2018 A6A12_RS08380 b243e0a597236cf699019f5664d9f748 248 SUPERFAMILY SSF102712 7 134 5.62E-19 T 28-03-2018 A6A12_RS08380 b243e0a597236cf699019f5664d9f748 248 Pfam PF00877 NlpC/P60 family 123 244 5.4E-15 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain A6A12_RS10270 eddffe1cdd89c10c94c77b30f179c482 377 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 9.3E-42 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A6A12_RS10270 eddffe1cdd89c10c94c77b30f179c482 377 Pfam PF07196 Flagellin hook IN motif 195 248 7.1E-12 T 28-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 A6A12_RS10270 eddffe1cdd89c10c94c77b30f179c482 377 SUPERFAMILY SSF64518 1 376 1.27E-94 T 28-03-2018 A6A12_RS10270 eddffe1cdd89c10c94c77b30f179c482 377 Gene3D G3DSA:1.20.1330.10 40 349 2.6E-69 T 28-03-2018 A6A12_RS10270 eddffe1cdd89c10c94c77b30f179c482 377 PRINTS PR00207 Flagellin signature 37 54 2.5E-27 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A6A12_RS10270 eddffe1cdd89c10c94c77b30f179c482 377 PRINTS PR00207 Flagellin signature 111 134 2.5E-27 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A6A12_RS10270 eddffe1cdd89c10c94c77b30f179c482 377 PRINTS PR00207 Flagellin signature 76 95 2.5E-27 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A6A12_RS10270 eddffe1cdd89c10c94c77b30f179c482 377 Pfam PF00700 Bacterial flagellin C-terminal helical region 292 376 1.9E-25 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A6A12_RS12555 88827112dd3750c0c8807c6887bb1482 599 Gene3D G3DSA:3.40.50.720 396 560 8.9E-19 T 28-03-2018 A6A12_RS12555 88827112dd3750c0c8807c6887bb1482 599 PRINTS PR00335 TrkA potassium uptake protein signature 458 468 7.2E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A6A12_RS12555 88827112dd3750c0c8807c6887bb1482 599 PRINTS PR00335 TrkA potassium uptake protein signature 418 432 7.2E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A6A12_RS12555 88827112dd3750c0c8807c6887bb1482 599 PRINTS PR00335 TrkA potassium uptake protein signature 447 457 7.2E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A6A12_RS12555 88827112dd3750c0c8807c6887bb1482 599 PRINTS PR00335 TrkA potassium uptake protein signature 401 415 7.2E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A6A12_RS12555 88827112dd3750c0c8807c6887bb1482 599 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 15 282 3.8E-80 T 28-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 A6A12_RS12555 88827112dd3750c0c8807c6887bb1482 599 Gene3D G3DSA:1.20.91.10 227 307 1.2E-11 T 28-03-2018 A6A12_RS12555 88827112dd3750c0c8807c6887bb1482 599 Pfam PF02254 TrkA-N domain 402 513 8.1E-24 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A6A12_RS12555 88827112dd3750c0c8807c6887bb1482 599 Pfam PF00999 Sodium/hydrogen exchanger family 12 371 2.2E-66 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A6A12_RS12555 88827112dd3750c0c8807c6887bb1482 599 SUPERFAMILY SSF51735 401 530 5.92E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS12555 88827112dd3750c0c8807c6887bb1482 599 Hamap MF_01412 Glutathione-regulated potassium-efflux system protein KefB [kefB]. 3 598 48.548 T 28-03-2018 IPR020884 Glutathione-regulated potassium-efflux system protein KefB GO:0005886|GO:0006813|GO:0015503 A6A12_RS05850 443935f60ff8ad17353fac1a0e60eabb 276 Gene3D G3DSA:3.40.50.720 2 126 1.4E-8 T 28-03-2018 A6A12_RS05850 443935f60ff8ad17353fac1a0e60eabb 276 SUPERFAMILY SSF51735 8 266 3.1E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS05850 443935f60ff8ad17353fac1a0e60eabb 276 Pfam PF13460 NAD(P)H-binding 9 172 3.6E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS05850 443935f60ff8ad17353fac1a0e60eabb 276 Gene3D G3DSA:3.90.25.10 166 273 5.1E-5 T 28-03-2018 A6A12_RS06740 5de0319e6f70e2cff3e4f8f52e2d2815 315 Gene3D G3DSA:3.40.50.620 2 159 7.7E-19 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS06740 5de0319e6f70e2cff3e4f8f52e2d2815 315 Pfam PF00582 Universal stress protein family 226 301 2.4E-14 T 28-03-2018 IPR006016 UspA GO:0006950 A6A12_RS06740 5de0319e6f70e2cff3e4f8f52e2d2815 315 Pfam PF00582 Universal stress protein family 4 148 2.7E-13 T 28-03-2018 IPR006016 UspA GO:0006950 A6A12_RS06740 5de0319e6f70e2cff3e4f8f52e2d2815 315 Gene3D G3DSA:3.40.50.620 166 304 3.5E-20 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS06740 5de0319e6f70e2cff3e4f8f52e2d2815 315 SUPERFAMILY SSF52402 173 309 6.03E-22 T 28-03-2018 A6A12_RS06740 5de0319e6f70e2cff3e4f8f52e2d2815 315 SUPERFAMILY SSF52402 4 159 1.59E-26 T 28-03-2018 A6A12_RS08465 ae41f3037e38026ab70ad183aca82b15 119 SMART SM00507 56 110 7.2E-10 T 28-03-2018 IPR003615 HNH nuclease A6A12_RS08465 ae41f3037e38026ab70ad183aca82b15 119 Pfam PF01844 HNH endonuclease 69 114 1.9E-13 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 A6A12_RS08465 ae41f3037e38026ab70ad183aca82b15 119 Gene3D G3DSA:3.40.1800.10 49 119 1.1E-16 T 28-03-2018 A6A12_RS04765 e0c2bc7711639ce004732086f07be2f2 329 SMART SM00729 14 219 2.4E-4 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A6A12_RS04765 e0c2bc7711639ce004732086f07be2f2 329 Pfam PF06463 Molybdenum Cofactor Synthesis C 186 312 5.3E-39 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 A6A12_RS04765 e0c2bc7711639ce004732086f07be2f2 329 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 6 329 1.2E-103 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 A6A12_RS04765 e0c2bc7711639ce004732086f07be2f2 329 Pfam PF04055 Radical SAM superfamily 19 181 2.7E-24 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A6A12_RS04765 e0c2bc7711639ce004732086f07be2f2 329 Gene3D G3DSA:3.20.20.70 1 329 9.9E-67 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS04765 e0c2bc7711639ce004732086f07be2f2 329 SUPERFAMILY SSF102114 7 278 1.7E-67 T 28-03-2018 A6A12_RS04765 e0c2bc7711639ce004732086f07be2f2 329 Pfam PF13353 4Fe-4S single cluster domain 23 125 7.7E-8 T 28-03-2018 A6A12_RS04765 e0c2bc7711639ce004732086f07be2f2 329 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 329 36.333 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 A6A12_RS11530 54f8cb26cdecb8f1ea3840f9fbe1662c 391 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 14 381 41.317 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 A6A12_RS11530 54f8cb26cdecb8f1ea3840f9fbe1662c 391 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 16 372 5.6E-130 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 A6A12_RS11530 54f8cb26cdecb8f1ea3840f9fbe1662c 391 Pfam PF01098 Cell cycle protein 18 373 1.7E-114 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 A6A12_RS11530 54f8cb26cdecb8f1ea3840f9fbe1662c 391 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 331 355 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 Gene3D G3DSA:1.10.1420.10 415 542 1.9E-29 T 28-03-2018 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 Pfam PF01624 MutS domain I 16 127 2.1E-42 T 28-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 SMART SM00534 614 801 6.1E-118 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 Gene3D G3DSA:1.10.1420.10 271 414 1.3E-41 T 28-03-2018 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 Gene3D G3DSA:3.30.420.110 140 270 4.4E-27 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 SUPERFAMILY SSF48334 275 572 5.75E-92 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 15 854 25.212 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 Gene3D G3DSA:3.40.1170.10 3 139 3.2E-47 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 Pfam PF05190 MutS family domain IV 435 525 2.0E-29 T 28-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 Gene3D G3DSA:3.40.50.300 574 826 1.9E-43 T 28-03-2018 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 Pfam PF05188 MutS domain II 136 261 9.8E-32 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 PIRSF PIRSF037677 8 836 3.1E-158 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 SUPERFAMILY SSF53150 122 274 1.14E-40 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 15 860 0.0 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 SMART SM00533 291 598 1.1E-107 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 Pfam PF00488 MutS domain V 617 804 1.6E-86 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 SUPERFAMILY SSF55271 11 121 2.88E-42 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 695 711 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 Pfam PF05192 MutS domain III 277 564 4.9E-40 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 A6A12_RS02420 1b5924ed8f6800ab5583b6851d5d68d6 862 SUPERFAMILY SSF52540 574 804 1.13E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01635 c2c82bd90ab85d182fc1e73461d73b1c 199 Pfam PF07963 Prokaryotic N-terminal methylation motif 21 42 1.9E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS01635 c2c82bd90ab85d182fc1e73461d73b1c 199 Gene3D G3DSA:3.30.700.10 23 191 5.6E-5 T 28-03-2018 A6A12_RS01635 c2c82bd90ab85d182fc1e73461d73b1c 199 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 21 42 3.4E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS01635 c2c82bd90ab85d182fc1e73461d73b1c 199 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 21 41 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS09320 d6f739799494782dd4ff269dab57499f 411 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 355 4.1E-28 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A6A12_RS09320 d6f739799494782dd4ff269dab57499f 411 Gene3D G3DSA:3.40.47.10 259 408 7.1E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS09320 d6f739799494782dd4ff269dab57499f 411 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 161 177 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site A6A12_RS09320 d6f739799494782dd4ff269dab57499f 411 SUPERFAMILY SSF53901 13 241 1.18E-37 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS09320 d6f739799494782dd4ff269dab57499f 411 SMART SM00825 Beta-ketoacyl synthase 67 349 2.0E-9 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A6A12_RS09320 d6f739799494782dd4ff269dab57499f 411 Gene3D G3DSA:3.40.47.10 7 254 9.0E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS09320 d6f739799494782dd4ff269dab57499f 411 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 105 240 2.3E-17 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A6A12_RS09320 d6f739799494782dd4ff269dab57499f 411 SUPERFAMILY SSF53901 216 402 4.17E-46 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS06265 0982a074fd5908ced4f53790b0923b2f 505 SUPERFAMILY SSF100950 5 233 1.81E-71 T 28-03-2018 A6A12_RS06265 0982a074fd5908ced4f53790b0923b2f 505 Gene3D G3DSA:3.40.1080.10 235 478 1.3E-34 T 28-03-2018 A6A12_RS06265 0982a074fd5908ced4f53790b0923b2f 505 PIRSF PIRSF009451 6 504 9.2E-248 T 28-03-2018 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 A6A12_RS06265 0982a074fd5908ced4f53790b0923b2f 505 SUPERFAMILY SSF100950 236 502 9.77E-57 T 28-03-2018 A6A12_RS06265 0982a074fd5908ced4f53790b0923b2f 505 Gene3D G3DSA:3.40.1080.10 2 233 1.0E-45 T 28-03-2018 A6A12_RS06265 0982a074fd5908ced4f53790b0923b2f 505 Pfam PF04223 Citrate lyase, alpha subunit (CitF) 38 502 1.6E-241 T 28-03-2018 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 A6A12_RS06265 0982a074fd5908ced4f53790b0923b2f 505 TIGRFAM TIGR01584 citF: citrate lyase, alpha subunit 35 504 5.0E-230 T 28-03-2018 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 A6A12_RS09710 46a135bc388216eb47ec79cd30067cd0 174 Pfam PF02620 Uncharacterized ACR, COG1399 62 173 9.1E-17 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD A6A12_RS12445 c9b33d9f4ece64d65136a5cbb97a0a28 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 28-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12445 c9b33d9f4ece64d65136a5cbb97a0a28 179 PIRSF PIRSF002161 1 179 2.5E-66 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12445 c9b33d9f4ece64d65136a5cbb97a0a28 179 Pfam PF00281 Ribosomal protein L5 24 80 7.6E-29 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12445 c9b33d9f4ece64d65136a5cbb97a0a28 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 44.969 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12445 c9b33d9f4ece64d65136a5cbb97a0a28 179 Gene3D G3DSA:3.30.1440.10 1 179 3.3E-80 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12445 c9b33d9f4ece64d65136a5cbb97a0a28 179 SUPERFAMILY SSF55282 4 179 1.39E-78 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12445 c9b33d9f4ece64d65136a5cbb97a0a28 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 2.5E-41 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS00740 3b021e9daec6e081f14b57e6a758de61 243 SUPERFAMILY SSF52402 14 229 1.35E-48 T 28-03-2018 A6A12_RS00740 3b021e9daec6e081f14b57e6a758de61 243 Gene3D G3DSA:3.90.1490.10 159 238 9.0E-10 T 28-03-2018 A6A12_RS00740 3b021e9daec6e081f14b57e6a758de61 243 Pfam PF01902 Diphthamide synthase 19 209 1.1E-19 T 28-03-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A6A12_RS00740 3b021e9daec6e081f14b57e6a758de61 243 Gene3D G3DSA:3.40.50.620 13 157 8.8E-16 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS11770 0013cf1131c22ad426812c2192ce432c 440 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 370 400 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site A6A12_RS11770 0013cf1131c22ad426812c2192ce432c 440 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 19 439 67.437 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 A6A12_RS11770 0013cf1131c22ad426812c2192ce432c 440 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 421 431 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site A6A12_RS11770 0013cf1131c22ad426812c2192ce432c 440 SUPERFAMILY SSF53335 77 438 4.86E-85 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS11770 0013cf1131c22ad426812c2192ce432c 440 Gene3D G3DSA:3.40.50.150 84 437 1.1E-56 T 28-03-2018 A6A12_RS11770 0013cf1131c22ad426812c2192ce432c 440 SUPERFAMILY SSF50249 17 74 4.91E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS11770 0013cf1131c22ad426812c2192ce432c 440 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 99 436 1.3E-32 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A6A12_RS11770 0013cf1131c22ad426812c2192ce432c 440 Pfam PF01938 TRAM domain 16 68 2.7E-10 T 28-03-2018 IPR002792 TRAM domain A6A12_RS11770 0013cf1131c22ad426812c2192ce432c 440 Gene3D G3DSA:2.40.50.140 1 83 1.4E-26 T 28-03-2018 A6A12_RS11770 0013cf1131c22ad426812c2192ce432c 440 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 25 431 1.8E-127 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 A6A12_RS06835 2e84648dcadef4cad68f45b853706aa1 195 SUPERFAMILY SSF53448 10 187 2.11E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS06835 2e84648dcadef4cad68f45b853706aa1 195 Pfam PF12804 MobA-like NTP transferase domain 10 161 2.6E-35 T 28-03-2018 IPR025877 MobA-like NTP transferase A6A12_RS06835 2e84648dcadef4cad68f45b853706aa1 195 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 8 188 2.9E-74 T 28-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 A6A12_RS06835 2e84648dcadef4cad68f45b853706aa1 195 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 5 190 29.968 T 28-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 A6A12_RS06835 2e84648dcadef4cad68f45b853706aa1 195 Gene3D G3DSA:3.90.550.10 5 194 1.2E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS08825 12288793688402d8d5014dc60d62d2a6 378 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 378 3.7E-172 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A6A12_RS08825 12288793688402d8d5014dc60d62d2a6 378 PIRSF PIRSF000267 2 377 9.9E-125 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A6A12_RS08825 12288793688402d8d5014dc60d62d2a6 378 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 361 1.2E-108 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A6A12_RS12450 90f9c97b4c2183de9d5d15163ac30204 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 8 25 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12450 90f9c97b4c2183de9d5d15163ac30204 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 97 19.855 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12450 90f9c97b4c2183de9d5d15163ac30204 105 Gene3D G3DSA:2.30.30.30 2 93 1.6E-30 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 A6A12_RS12450 90f9c97b4c2183de9d5d15163ac30204 105 SUPERFAMILY SSF50104 4 102 1.69E-34 T 28-03-2018 IPR008991 Translation protein SH3-like domain A6A12_RS12450 90f9c97b4c2183de9d5d15163ac30204 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 39 102 6.9E-24 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12450 90f9c97b4c2183de9d5d15163ac30204 105 SMART SM00739 4 31 6.1E-4 T 28-03-2018 IPR005824 KOW A6A12_RS12450 90f9c97b4c2183de9d5d15163ac30204 105 Pfam PF00467 KOW motif 8 37 3.7E-5 T 28-03-2018 IPR005824 KOW A6A12_RS12450 90f9c97b4c2183de9d5d15163ac30204 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 103 1.1E-39 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS04170 4d1344d0bd3a02c92428a3e16da6fdae 240 SUPERFAMILY SSF52172 5 131 8.11E-35 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS04170 4d1344d0bd3a02c92428a3e16da6fdae 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 231 1.8E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS04170 4d1344d0bd3a02c92428a3e16da6fdae 240 Gene3D G3DSA:1.10.10.10 129 237 1.4E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS04170 4d1344d0bd3a02c92428a3e16da6fdae 240 SMART SM00862 155 231 1.4E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS04170 4d1344d0bd3a02c92428a3e16da6fdae 240 Pfam PF00072 Response regulator receiver domain 11 119 6.5E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS04170 4d1344d0bd3a02c92428a3e16da6fdae 240 SMART SM00448 9 119 4.7E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS04170 4d1344d0bd3a02c92428a3e16da6fdae 240 Gene3D G3DSA:3.40.50.2300 1 128 1.6E-30 T 28-03-2018 A6A12_RS04170 4d1344d0bd3a02c92428a3e16da6fdae 240 SUPERFAMILY SSF46894 129 232 4.25E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS05195 2400cdb83c0a3ea8c40d8a1fd09be796 426 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 319 396 6.9E-16 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A6A12_RS05195 2400cdb83c0a3ea8c40d8a1fd09be796 426 Pfam PF06689 ClpX C4-type zinc finger 14 51 1.2E-20 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A6A12_RS05195 2400cdb83c0a3ea8c40d8a1fd09be796 426 SMART SM00382 113 266 2.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS05195 2400cdb83c0a3ea8c40d8a1fd09be796 426 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 312 2.5E-48 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A6A12_RS05195 2400cdb83c0a3ea8c40d8a1fd09be796 426 SMART SM01086 319 414 1.2E-34 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A6A12_RS05195 2400cdb83c0a3ea8c40d8a1fd09be796 426 SUPERFAMILY SSF52540 63 404 3.53E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05195 2400cdb83c0a3ea8c40d8a1fd09be796 426 SMART SM00994 13 52 1.0E-24 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 A6A12_RS05195 2400cdb83c0a3ea8c40d8a1fd09be796 426 Gene3D G3DSA:3.40.50.300 57 317 2.2E-68 T 28-03-2018 A6A12_RS05195 2400cdb83c0a3ea8c40d8a1fd09be796 426 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 11 414 2.5E-211 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A6A12_RS05195 2400cdb83c0a3ea8c40d8a1fd09be796 426 SUPERFAMILY SSF57716 14 49 5.84E-12 T 28-03-2018 A6A12_RS05195 2400cdb83c0a3ea8c40d8a1fd09be796 426 Gene3D G3DSA:1.10.8.60 319 411 5.0E-33 T 28-03-2018 A6A12_RS05195 2400cdb83c0a3ea8c40d8a1fd09be796 426 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 5 417 53.381 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 A6A12_RS01195 33703771300c5c0312f5f8a9ec388af8 164 PIRSF PIRSF016548 3 164 1.5E-68 T 28-03-2018 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 A6A12_RS01195 33703771300c5c0312f5f8a9ec388af8 164 Pfam PF04353 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ 3 154 3.1E-54 T 28-03-2018 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 A6A12_RS00895 e00fd716ae61e0ff784842eadaea83f7 339 PIRSF PIRSF002786 4 331 3.7E-66 T 28-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 A6A12_RS00895 e00fd716ae61e0ff784842eadaea83f7 339 SUPERFAMILY SSF158544 218 285 3.66E-19 T 28-03-2018 A6A12_RS00895 e00fd716ae61e0ff784842eadaea83f7 339 SUPERFAMILY SSF54523 39 103 5.81E-35 T 28-03-2018 A6A12_RS00895 e00fd716ae61e0ff784842eadaea83f7 339 SUPERFAMILY SSF54523 288 328 5.81E-35 T 28-03-2018 A6A12_RS00895 e00fd716ae61e0ff784842eadaea83f7 339 Pfam PF03934 Type II secretion system (T2SS), protein K 33 320 1.3E-85 T 28-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 A6A12_RS00895 e00fd716ae61e0ff784842eadaea83f7 339 SUPERFAMILY SSF158544 104 216 1.12E-30 T 28-03-2018 A6A12_RS00895 e00fd716ae61e0ff784842eadaea83f7 339 Gene3D G3DSA:1.10.40.60 220 285 3.0E-21 T 28-03-2018 A6A12_RS00895 e00fd716ae61e0ff784842eadaea83f7 339 Gene3D G3DSA:1.10.40.60 102 218 1.0E-29 T 28-03-2018 A6A12_RS06495 8e13499241d37422e043fcdf3fb902cb 109 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 3 109 1.2E-47 T 28-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE A6A12_RS06495 8e13499241d37422e043fcdf3fb902cb 109 PIRSF PIRSF006223 2 109 1.4E-39 T 28-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE A6A12_RS06495 8e13499241d37422e043fcdf3fb902cb 109 Pfam PF04358 DsrC like protein 3 109 5.1E-43 T 28-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE A6A12_RS06495 8e13499241d37422e043fcdf3fb902cb 109 Gene3D G3DSA:3.30.1420.10 2 39 2.3E-16 T 28-03-2018 A6A12_RS06495 8e13499241d37422e043fcdf3fb902cb 109 SUPERFAMILY SSF69721 2 109 1.11E-39 T 28-03-2018 IPR025526 DsrC-like domain A6A12_RS06495 8e13499241d37422e043fcdf3fb902cb 109 Gene3D G3DSA:1.10.10.370 40 108 3.1E-31 T 28-03-2018 A6A12_RS05920 256c9ee28f7fe2c100bc674dbe9ef981 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 294 3.2E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS05920 256c9ee28f7fe2c100bc674dbe9ef981 295 SUPERFAMILY SSF161098 89 276 7.33E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS05920 256c9ee28f7fe2c100bc674dbe9ef981 295 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 14 65 5.1E-13 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A6A12_RS05920 256c9ee28f7fe2c100bc674dbe9ef981 295 Gene3D G3DSA:1.10.3720.10 14 284 5.7E-34 T 28-03-2018 A6A12_RS13920 ba1bd9c853902b7ff34fbde2f9381796 254 Gene3D G3DSA:3.40.190.10 144 249 1.4E-8 T 28-03-2018 A6A12_RS13920 ba1bd9c853902b7ff34fbde2f9381796 254 Gene3D G3DSA:3.40.190.10 29 143 3.6E-8 T 28-03-2018 A6A12_RS13920 ba1bd9c853902b7ff34fbde2f9381796 254 SUPERFAMILY SSF53850 33 246 1.88E-31 T 28-03-2018 A6A12_RS13920 ba1bd9c853902b7ff34fbde2f9381796 254 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 33 245 6.7E-18 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS11070 1b7db56ebd5b241a2a30dab6446bf0c8 414 PIRSF PIRSF016055 1 414 2.8E-200 T 28-03-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 A6A12_RS11070 1b7db56ebd5b241a2a30dab6446bf0c8 414 Hamap MF_00426 Na(+)-translocating NADH-quinone reductase subunit B [nqrB]. 2 412 36.518 T 28-03-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 A6A12_RS11070 1b7db56ebd5b241a2a30dab6446bf0c8 414 TIGRFAM TIGR01937 nqrB: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit 3 408 1.5E-202 T 28-03-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 A6A12_RS11070 1b7db56ebd5b241a2a30dab6446bf0c8 414 Pfam PF03116 NQR2, RnfD, RnfE family 41 405 1.5E-107 T 28-03-2018 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 A6A12_RS10070 dd3982345cc235546a012921c5680f6f 177 TIGRFAM TIGR01752 flav_long: flavodoxin 4 170 1.2E-71 T 28-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 A6A12_RS10070 dd3982345cc235546a012921c5680f6f 177 SUPERFAMILY SSF52218 4 172 4.66E-51 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS10070 dd3982345cc235546a012921c5680f6f 177 Gene3D G3DSA:3.40.50.360 4 172 4.0E-38 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS10070 dd3982345cc235546a012921c5680f6f 177 Pfam PF00258 Flavodoxin 6 162 4.8E-32 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A6A12_RS10070 dd3982345cc235546a012921c5680f6f 177 PIRSF PIRSF038996 1 174 1.0E-66 T 28-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 A6A12_RS10070 dd3982345cc235546a012921c5680f6f 177 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 A6A12_RS01920 38ef84bbe5fd35655b194418bc95fd9e 272 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 99 7.8E-24 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal A6A12_RS01920 38ef84bbe5fd35655b194418bc95fd9e 272 Gene3D G3DSA:1.10.3730.10 165 272 6.8E-31 T 28-03-2018 A6A12_RS01920 38ef84bbe5fd35655b194418bc95fd9e 272 SUPERFAMILY SSF48179 162 270 1.7E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A6A12_RS01920 38ef84bbe5fd35655b194418bc95fd9e 272 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 268 1.3E-29 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 A6A12_RS01920 38ef84bbe5fd35655b194418bc95fd9e 272 Gene3D G3DSA:3.40.50.720 1 164 5.6E-30 T 28-03-2018 A6A12_RS01920 38ef84bbe5fd35655b194418bc95fd9e 272 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 268 8.2E-73 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A6A12_RS01920 38ef84bbe5fd35655b194418bc95fd9e 272 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 268 26.13 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A6A12_RS01920 38ef84bbe5fd35655b194418bc95fd9e 272 SUPERFAMILY SSF51735 4 160 5.39E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS01920 38ef84bbe5fd35655b194418bc95fd9e 272 PIRSF PIRSF000193 3 270 2.6E-76 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A6A12_RS01920 38ef84bbe5fd35655b194418bc95fd9e 272 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 224 246 - T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 A6A12_RS12055 c1d529c3bfa9c9efdbb51f9096d21bf2 458 Pfam PF13638 PIN domain 9 150 2.5E-34 T 28-03-2018 IPR002716 PIN domain A6A12_RS12055 c1d529c3bfa9c9efdbb51f9096d21bf2 458 SUPERFAMILY SSF52540 247 437 1.69E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12055 c1d529c3bfa9c9efdbb51f9096d21bf2 458 Pfam PF02562 PhoH-like protein 248 452 2.1E-54 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 A6A12_RS12055 c1d529c3bfa9c9efdbb51f9096d21bf2 458 SMART SM00670 7 141 9.6E-11 T 28-03-2018 IPR002716 PIN domain A6A12_RS12055 c1d529c3bfa9c9efdbb51f9096d21bf2 458 SUPERFAMILY SSF88723 104 156 4.9E-14 T 28-03-2018 IPR029060 PIN domain-like A6A12_RS12055 c1d529c3bfa9c9efdbb51f9096d21bf2 458 SUPERFAMILY SSF88723 7 68 4.9E-14 T 28-03-2018 IPR029060 PIN domain-like A6A12_RS12055 c1d529c3bfa9c9efdbb51f9096d21bf2 458 Gene3D G3DSA:3.40.50.300 250 453 4.2E-21 T 28-03-2018 A6A12_RS12055 c1d529c3bfa9c9efdbb51f9096d21bf2 458 Gene3D G3DSA:3.40.50.1010 6 249 5.0E-31 T 28-03-2018 IPR029060 PIN domain-like A6A12_RS11355 39cf25dac28f15bfb679761742fbcf07 305 SUPERFAMILY SSF51658 18 295 1.7E-100 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A6A12_RS11355 39cf25dac28f15bfb679761742fbcf07 305 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 86 94 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A6A12_RS11355 39cf25dac28f15bfb679761742fbcf07 305 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 232 248 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A6A12_RS11355 39cf25dac28f15bfb679761742fbcf07 305 Hamap MF_00152 Probable endonuclease 4 [nfo]. 19 296 41.762 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A6A12_RS11355 39cf25dac28f15bfb679761742fbcf07 305 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 192 199 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 A6A12_RS11355 39cf25dac28f15bfb679761742fbcf07 305 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 20 293 1.4E-105 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A6A12_RS11355 39cf25dac28f15bfb679761742fbcf07 305 SMART SM00518 20 296 4.1E-119 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A6A12_RS11355 39cf25dac28f15bfb679761742fbcf07 305 Gene3D G3DSA:3.20.20.150 18 302 1.4E-58 T 28-03-2018 A6A12_RS11355 39cf25dac28f15bfb679761742fbcf07 305 Pfam PF01261 Xylose isomerase-like TIM barrel 37 256 5.1E-41 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A6A12_RS13350 bff950884b3c63244b1f6e37292d0979 565 Gene3D G3DSA:3.40.50.970 1 194 5.2E-40 T 28-03-2018 A6A12_RS13350 bff950884b3c63244b1f6e37292d0979 565 SUPERFAMILY SSF52518 1 184 1.53E-42 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS13350 bff950884b3c63244b1f6e37292d0979 565 Gene3D G3DSA:3.40.50.970 338 543 3.1E-27 T 28-03-2018 A6A12_RS13350 bff950884b3c63244b1f6e37292d0979 565 SUPERFAMILY SSF52467 203 351 1.03E-28 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A6A12_RS13350 bff950884b3c63244b1f6e37292d0979 565 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 176 3.2E-45 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A6A12_RS13350 bff950884b3c63244b1f6e37292d0979 565 Gene3D G3DSA:3.40.50.1220 201 337 1.3E-25 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A6A12_RS13350 bff950884b3c63244b1f6e37292d0979 565 SUPERFAMILY SSF52518 367 563 7.27E-41 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS13350 bff950884b3c63244b1f6e37292d0979 565 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 204 328 3.1E-25 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 A6A12_RS13350 bff950884b3c63244b1f6e37292d0979 565 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 390 538 6.1E-33 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A6A12_RS09270 1a49f294ea96513ba96a9631440257c4 85 SUPERFAMILY SSF47336 4 82 2.09E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A6A12_RS09270 1a49f294ea96513ba96a9631440257c4 85 Hamap MF_01217 Acyl carrier protein [acpP]. 8 82 14.289 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A6A12_RS09270 1a49f294ea96513ba96a9631440257c4 85 Pfam PF00550 Phosphopantetheine attachment site 11 76 2.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A6A12_RS09270 1a49f294ea96513ba96a9631440257c4 85 Gene3D G3DSA:1.10.1200.10 1 85 2.8E-18 T 28-03-2018 A6A12_RS07245 5c265379cf81722f2c0ad25ec2f5b013 478 Gene3D G3DSA:3.20.20.80 3 478 5.8E-150 T 28-03-2018 A6A12_RS07245 5c265379cf81722f2c0ad25ec2f5b013 478 SUPERFAMILY SSF51445 4 476 2.91E-160 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A6A12_RS07245 5c265379cf81722f2c0ad25ec2f5b013 478 Pfam PF00232 Glycosyl hydrolase family 1 4 475 2.2E-131 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A6A12_RS07245 5c265379cf81722f2c0ad25ec2f5b013 478 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 372 380 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site A6A12_RS07245 5c265379cf81722f2c0ad25ec2f5b013 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 393 404 2.5E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A6A12_RS07245 5c265379cf81722f2c0ad25ec2f5b013 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 440 452 2.5E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A6A12_RS07245 5c265379cf81722f2c0ad25ec2f5b013 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 372 380 2.5E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A6A12_RS07245 5c265379cf81722f2c0ad25ec2f5b013 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 415 432 2.5E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A6A12_RS07245 5c265379cf81722f2c0ad25ec2f5b013 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 306 320 2.5E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A6A12_RS07245 5c265379cf81722f2c0ad25ec2f5b013 478 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 10 24 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site A6A12_RS11230 e16f21ff5a97802a7acab87a207835e7 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.5E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS11230 e16f21ff5a97802a7acab87a207835e7 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.5E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS11230 e16f21ff5a97802a7acab87a207835e7 332 SUPERFAMILY SSF47413 1 59 6.27E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS11230 e16f21ff5a97802a7acab87a207835e7 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 A6A12_RS11230 e16f21ff5a97802a7acab87a207835e7 332 Gene3D G3DSA:3.40.50.2300 175 309 1.3E-44 T 28-03-2018 A6A12_RS11230 e16f21ff5a97802a7acab87a207835e7 332 SMART SM00354 1 71 1.6E-33 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS11230 e16f21ff5a97802a7acab87a207835e7 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.8E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS11230 e16f21ff5a97802a7acab87a207835e7 332 Pfam PF13377 Periplasmic binding protein-like domain 168 329 2.7E-36 T 28-03-2018 A6A12_RS11230 e16f21ff5a97802a7acab87a207835e7 332 SUPERFAMILY SSF53822 61 330 2.55E-83 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A6A12_RS11230 e16f21ff5a97802a7acab87a207835e7 332 Gene3D G3DSA:3.40.50.2300 55 174 1.5E-34 T 28-03-2018 A6A12_RS11230 e16f21ff5a97802a7acab87a207835e7 332 Gene3D G3DSA:1.10.260.40 2 54 1.5E-20 T 28-03-2018 A6A12_RS09945 1b5a1156bd38ba8ddc49081642d6695b 198 Gene3D G3DSA:3.10.180.10 9 197 4.1E-66 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A6A12_RS09945 1b5a1156bd38ba8ddc49081642d6695b 198 SUPERFAMILY SSF54593 5 197 4.89E-63 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A6A12_RS09945 1b5a1156bd38ba8ddc49081642d6695b 198 Pfam PF06185 YecM protein 13 196 1.9E-67 T 28-03-2018 IPR010393 Protein of unknown function DUF991 A6A12_RS13095 130151b1ab6994f99d5249beafc52e37 151 Pfam PF00364 Biotin-requiring enzyme 76 150 1.2E-23 T 28-03-2018 IPR000089 Biotin/lipoyl attachment A6A12_RS13095 130151b1ab6994f99d5249beafc52e37 151 Gene3D G3DSA:2.40.50.100 4 151 1.1E-20 T 28-03-2018 A6A12_RS13095 130151b1ab6994f99d5249beafc52e37 151 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 107 124 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A6A12_RS13095 130151b1ab6994f99d5249beafc52e37 151 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 97 111 1.4E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A6A12_RS13095 130151b1ab6994f99d5249beafc52e37 151 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 80 93 1.4E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A6A12_RS13095 130151b1ab6994f99d5249beafc52e37 151 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 112 125 1.4E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A6A12_RS13095 130151b1ab6994f99d5249beafc52e37 151 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 151 2.1E-60 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 A6A12_RS13095 130151b1ab6994f99d5249beafc52e37 151 SUPERFAMILY SSF51230 76 151 2.49E-25 T 28-03-2018 IPR011053 Single hybrid motif A6A12_RS10035 d56d2cd31440e6a6470d78e23fe47610 429 Gene3D G3DSA:1.10.230.10 282 379 3.5E-37 T 28-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain A6A12_RS10035 d56d2cd31440e6a6470d78e23fe47610 429 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 15 421 9.9E-239 T 28-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 A6A12_RS10035 d56d2cd31440e6a6470d78e23fe47610 429 ProSitePatterns PS00480 Citrate synthase signature. 303 315 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A6A12_RS10035 d56d2cd31440e6a6470d78e23fe47610 429 PRINTS PR00143 Citrate synthase signature 241 269 1.6E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS10035 d56d2cd31440e6a6470d78e23fe47610 429 PRINTS PR00143 Citrate synthase signature 296 316 1.6E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS10035 d56d2cd31440e6a6470d78e23fe47610 429 PRINTS PR00143 Citrate synthase signature 219 234 1.6E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS10035 d56d2cd31440e6a6470d78e23fe47610 429 PRINTS PR00143 Citrate synthase signature 165 178 1.6E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS10035 d56d2cd31440e6a6470d78e23fe47610 429 PRINTS PR00143 Citrate synthase signature 359 375 1.6E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS10035 d56d2cd31440e6a6470d78e23fe47610 429 PRINTS PR00143 Citrate synthase signature 379 393 1.6E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS10035 d56d2cd31440e6a6470d78e23fe47610 429 Gene3D G3DSA:1.10.580.10 53 281 1.2E-77 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain A6A12_RS10035 d56d2cd31440e6a6470d78e23fe47610 429 Pfam PF00285 Citrate synthase, C-terminal domain 49 411 2.1E-134 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS10035 d56d2cd31440e6a6470d78e23fe47610 429 PIRSF PIRSF001369 38 429 2.3E-172 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type A6A12_RS10035 d56d2cd31440e6a6470d78e23fe47610 429 SUPERFAMILY SSF48256 4 428 4.45E-169 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS05145 dfabef86df596422adc3e94d14fc2601 417 Gene3D G3DSA:3.40.190.10 154 417 4.3E-29 T 28-03-2018 A6A12_RS05145 dfabef86df596422adc3e94d14fc2601 417 Gene3D G3DSA:3.40.190.10 25 153 2.9E-13 T 28-03-2018 A6A12_RS05145 dfabef86df596422adc3e94d14fc2601 417 Pfam PF01547 Bacterial extracellular solute-binding protein 62 288 6.3E-20 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 A6A12_RS05145 dfabef86df596422adc3e94d14fc2601 417 SUPERFAMILY SSF53850 23 417 2.23E-59 T 28-03-2018 A6A12_RS08835 81eb23a604e7f1e01b4ad146879699af 334 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 16 240 3.2E-115 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 A6A12_RS08835 81eb23a604e7f1e01b4ad146879699af 334 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 255 332 5.0E-37 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A6A12_RS08835 81eb23a604e7f1e01b4ad146879699af 334 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 258 331 2.3E-33 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 A6A12_RS08835 81eb23a604e7f1e01b4ad146879699af 334 Gene3D G3DSA:1.10.10.10 262 332 7.8E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS08835 81eb23a604e7f1e01b4ad146879699af 334 Gene3D G3DSA:1.10.8.60 189 259 1.8E-30 T 28-03-2018 A6A12_RS08835 81eb23a604e7f1e01b4ad146879699af 334 SUPERFAMILY SSF52540 25 256 6.25E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS08835 81eb23a604e7f1e01b4ad146879699af 334 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 28 331 1.3E-144 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A6A12_RS08835 81eb23a604e7f1e01b4ad146879699af 334 Gene3D G3DSA:3.40.50.300 23 186 2.7E-29 T 28-03-2018 A6A12_RS08835 81eb23a604e7f1e01b4ad146879699af 334 SMART SM00382 56 183 1.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS08835 81eb23a604e7f1e01b4ad146879699af 334 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 334 180.8 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 A6A12_RS08835 81eb23a604e7f1e01b4ad146879699af 334 SUPERFAMILY SSF46785 262 332 2.01E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS01250 5efca141e9735d831408f0afb1a01106 353 SUPERFAMILY SSF52540 113 338 3.43E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01250 5efca141e9735d831408f0afb1a01106 353 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 40 340 37.337 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 A6A12_RS01250 5efca141e9735d831408f0afb1a01106 353 Gene3D G3DSA:2.40.50.140 35 101 1.3E-15 T 28-03-2018 A6A12_RS01250 5efca141e9735d831408f0afb1a01106 353 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 74 334 3.3E-87 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 A6A12_RS01250 5efca141e9735d831408f0afb1a01106 353 Pfam PF03193 RsgA GTPase 99 276 7.8E-56 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 A6A12_RS01250 5efca141e9735d831408f0afb1a01106 353 Gene3D G3DSA:1.10.40.50 277 345 2.0E-21 T 28-03-2018 A6A12_RS01250 5efca141e9735d831408f0afb1a01106 353 Gene3D G3DSA:3.40.50.300 112 275 2.3E-24 T 28-03-2018 A6A12_RS14200 54de958117922ebeb51c88a6c5b8e166 154 Pfam PF01037 Lrp/AsnC ligand binding domain 75 145 1.0E-16 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A6A12_RS14200 54de958117922ebeb51c88a6c5b8e166 154 Pfam PF13404 AsnC-type helix-turn-helix domain 8 49 8.8E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A6A12_RS14200 54de958117922ebeb51c88a6c5b8e166 154 SUPERFAMILY SSF54909 69 154 4.83E-19 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel A6A12_RS14200 54de958117922ebeb51c88a6c5b8e166 154 Gene3D G3DSA:1.10.10.10 1 60 3.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS14200 54de958117922ebeb51c88a6c5b8e166 154 Gene3D G3DSA:3.30.70.920 61 153 7.0E-23 T 28-03-2018 A6A12_RS14200 54de958117922ebeb51c88a6c5b8e166 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 6.0E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A6A12_RS14200 54de958117922ebeb51c88a6c5b8e166 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 6.0E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A6A12_RS14200 54de958117922ebeb51c88a6c5b8e166 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 6.0E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A6A12_RS14200 54de958117922ebeb51c88a6c5b8e166 154 SUPERFAMILY SSF46785 7 68 5.64E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS14200 54de958117922ebeb51c88a6c5b8e166 154 SMART SM00344 8 115 1.5E-41 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A6A12_RS11790 24c1868e0bd5ccb2a55d7aa860be5063 246 Pfam PF11967 Recombination protein O N terminal 9 81 2.0E-23 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal A6A12_RS11790 24c1868e0bd5ccb2a55d7aa860be5063 246 TIGRFAM TIGR00613 reco: DNA repair protein RecO 11 232 6.3E-40 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A6A12_RS11790 24c1868e0bd5ccb2a55d7aa860be5063 246 Pfam PF02565 Recombination protein O C terminal 89 230 1.0E-23 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A6A12_RS11790 24c1868e0bd5ccb2a55d7aa860be5063 246 Hamap MF_00201 DNA repair protein RecO [recO]. 6 235 22.686 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 A6A12_RS11790 24c1868e0bd5ccb2a55d7aa860be5063 246 SUPERFAMILY SSF57863 90 169 7.59E-12 T 28-03-2018 A6A12_RS11790 24c1868e0bd5ccb2a55d7aa860be5063 246 Gene3D G3DSA:2.40.50.140 9 81 2.6E-25 T 28-03-2018 A6A12_RS11790 24c1868e0bd5ccb2a55d7aa860be5063 246 SUPERFAMILY SSF50249 10 80 6.51E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS10795 ec5e8412671a50b4ad45350ebc5620a8 252 Pfam PF00753 Metallo-beta-lactamase superfamily 14 166 4.6E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS10795 ec5e8412671a50b4ad45350ebc5620a8 252 SUPERFAMILY SSF56281 2 252 7.73E-68 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS10795 ec5e8412671a50b4ad45350ebc5620a8 252 PIRSF PIRSF005457 1 252 1.7E-100 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 A6A12_RS10795 ec5e8412671a50b4ad45350ebc5620a8 252 Gene3D G3DSA:3.60.15.10 1 252 5.2E-71 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS10795 ec5e8412671a50b4ad45350ebc5620a8 252 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 2 252 44.668 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 A6A12_RS10795 ec5e8412671a50b4ad45350ebc5620a8 252 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 4 252 3.0E-106 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 A6A12_RS10795 ec5e8412671a50b4ad45350ebc5620a8 252 SMART SM00849 12 166 1.7E-30 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS10795 ec5e8412671a50b4ad45350ebc5620a8 252 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 167 252 2.8E-27 T 28-03-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 A6A12_RS14410 0e9cfede34836794f8e1a2847a79c0c5 144 SUPERFAMILY SSF52218 2 143 1.74E-39 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS14410 0e9cfede34836794f8e1a2847a79c0c5 144 Gene3D G3DSA:3.40.50.360 1 144 8.2E-27 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS14410 0e9cfede34836794f8e1a2847a79c0c5 144 Pfam PF00258 Flavodoxin 4 132 4.6E-22 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A6A12_RS10385 886dac262147e386b92a0e381d6f3dfd 136 Gene3D G3DSA:3.40.50.9200 23 131 2.5E-17 T 28-03-2018 A6A12_RS10385 886dac262147e386b92a0e381d6f3dfd 136 SUPERFAMILY SSF52206 50 130 8.11E-8 T 28-03-2018 IPR015032 MTH538 TIR-like domain A6A12_RS10385 886dac262147e386b92a0e381d6f3dfd 136 Pfam PF08937 MTH538 TIR-like domain (DUF1863) 5 103 1.7E-10 T 28-03-2018 IPR015032 MTH538 TIR-like domain A6A12_RS01120 7f5da6a419b13dfafba52d7720dded9c 320 Pfam PF08279 HTH domain 9 59 2.7E-10 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 A6A12_RS01120 7f5da6a419b13dfafba52d7720dded9c 320 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 80 317 3.6E-68 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 A6A12_RS01120 7f5da6a419b13dfafba52d7720dded9c 320 SUPERFAMILY SSF50037 271 317 3.8E-10 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal A6A12_RS01120 7f5da6a419b13dfafba52d7720dded9c 320 SUPERFAMILY SSF55681 71 268 1.39E-58 T 28-03-2018 A6A12_RS01120 7f5da6a419b13dfafba52d7720dded9c 320 Gene3D G3DSA:1.10.10.10 1 64 3.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS01120 7f5da6a419b13dfafba52d7720dded9c 320 Gene3D G3DSA:2.30.30.100 271 317 8.4E-12 T 28-03-2018 A6A12_RS01120 7f5da6a419b13dfafba52d7720dded9c 320 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 7 317 32.84 T 28-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 A6A12_RS01120 7f5da6a419b13dfafba52d7720dded9c 320 Pfam PF03099 Biotin/lipoate A/B protein ligase family 83 207 7.5E-20 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 A6A12_RS01120 7f5da6a419b13dfafba52d7720dded9c 320 Gene3D G3DSA:3.30.930.10 65 270 7.7E-59 T 28-03-2018 A6A12_RS01120 7f5da6a419b13dfafba52d7720dded9c 320 SUPERFAMILY SSF46785 6 60 1.49E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS01120 7f5da6a419b13dfafba52d7720dded9c 320 Pfam PF02237 Biotin protein ligase C terminal domain 271 317 2.9E-10 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 A6A12_RS05480 21cd34126dceadc65ec3179e9a3aac7d 595 ProSitePatterns PS00211 ABC transporters family signature. 484 498 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS05480 21cd34126dceadc65ec3179e9a3aac7d 595 Pfam PF00005 ABC transporter 368 512 9.3E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS05480 21cd34126dceadc65ec3179e9a3aac7d 595 SUPERFAMILY SSF90123 12 330 7.46E-55 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A6A12_RS05480 21cd34126dceadc65ec3179e9a3aac7d 595 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 20 554 1.0E-178 T 28-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 A6A12_RS05480 21cd34126dceadc65ec3179e9a3aac7d 595 Gene3D G3DSA:1.20.1560.10 2 329 8.3E-45 T 28-03-2018 A6A12_RS05480 21cd34126dceadc65ec3179e9a3aac7d 595 Gene3D G3DSA:3.40.50.300 330 588 1.3E-56 T 28-03-2018 A6A12_RS05480 21cd34126dceadc65ec3179e9a3aac7d 595 SUPERFAMILY SSF52540 349 581 1.74E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05480 21cd34126dceadc65ec3179e9a3aac7d 595 SMART SM00382 375 558 5.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS05480 21cd34126dceadc65ec3179e9a3aac7d 595 Pfam PF00664 ABC transporter transmembrane region 25 292 6.7E-43 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A6A12_RS12550 6be58a8e02290dddaf3e0ca9192125f6 66 TIGRFAM TIGR02443 TIGR02443: conserved hypothetical protein 2 60 1.4E-32 T 28-03-2018 IPR012658 Conserved hypothetical protein CHP02443 A6A12_RS12550 6be58a8e02290dddaf3e0ca9192125f6 66 Pfam PF09526 Probable metal-binding protein (DUF2387) 4 52 9.5E-20 T 28-03-2018 IPR012658 Conserved hypothetical protein CHP02443 A6A12_RS11050 b385c9a47768731754b89d32616c18ab 407 Pfam PF00175 Oxidoreductase NAD-binding domain 277 385 2.2E-16 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A6A12_RS11050 b385c9a47768731754b89d32616c18ab 407 Gene3D G3DSA:2.40.30.10 137 256 5.8E-32 T 28-03-2018 A6A12_RS11050 b385c9a47768731754b89d32616c18ab 407 Hamap MF_00430 Na(+)-translocating NADH-quinone reductase subunit F [nqrF]. 1 407 62.516 T 28-03-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 A6A12_RS11050 b385c9a47768731754b89d32616c18ab 407 Gene3D G3DSA:3.40.50.80 257 401 1.6E-26 T 28-03-2018 A6A12_RS11050 b385c9a47768731754b89d32616c18ab 407 PIRSF PIRSF000044 1 407 3.6E-218 T 28-03-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 A6A12_RS11050 b385c9a47768731754b89d32616c18ab 407 SUPERFAMILY SSF54292 36 124 2.0E-21 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A6A12_RS11050 b385c9a47768731754b89d32616c18ab 407 SUPERFAMILY SSF63380 105 272 6.47E-35 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A6A12_RS11050 b385c9a47768731754b89d32616c18ab 407 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 43 115 6.7E-10 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A6A12_RS11050 b385c9a47768731754b89d32616c18ab 407 Pfam PF00970 Oxidoreductase FAD-binding domain 204 266 6.5E-9 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 A6A12_RS11050 b385c9a47768731754b89d32616c18ab 407 Gene3D G3DSA:3.10.20.30 29 136 1.5E-19 T 28-03-2018 IPR012675 Beta-grasp domain A6A12_RS11050 b385c9a47768731754b89d32616c18ab 407 SUPERFAMILY SSF52343 258 402 1.96E-35 T 28-03-2018 A6A12_RS11050 b385c9a47768731754b89d32616c18ab 407 TIGRFAM TIGR01941 nqrF: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit 3 407 3.9E-228 T 28-03-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 TIGRFAM TIGR00593 pola: DNA polymerase I 10 930 1.5E-289 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 Pfam PF01612 3'-5' exonuclease 330 516 1.5E-40 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 Pfam PF00476 DNA polymerase family A 553 927 1.8E-155 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 ProSitePatterns PS00447 DNA polymerase family A signature. 755 774 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 Gene3D G3DSA:3.30.70.370 770 930 1.7E-49 T 28-03-2018 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 SMART SM00474 330 517 1.7E-40 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 SMART SM00279 173 208 7.0E-14 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 SUPERFAMILY SSF47807 171 290 7.48E-32 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 SUPERFAMILY SSF88723 7 170 2.7E-57 T 28-03-2018 IPR029060 PIN domain-like A6A12_RS14055 763d127656fca69e567784df5c43212d 930 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 171 270 2.2E-30 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 SMART SM00475 7 268 2.2E-126 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 Gene3D G3DSA:3.40.50.1010 7 180 2.0E-68 T 28-03-2018 IPR029060 PIN domain-like A6A12_RS14055 763d127656fca69e567784df5c43212d 930 Gene3D G3DSA:3.30.70.370 659 769 4.8E-37 T 28-03-2018 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 846 862 1.6E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 656 678 1.6E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 701 724 1.6E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 731 744 1.6E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 755 780 1.6E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 814 825 1.6E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 679 694 1.6E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 792 803 1.6E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 877 890 1.6E-78 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 Gene3D G3DSA:1.20.1060.10 543 658 3.5E-33 T 28-03-2018 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 SMART SM00482 687 894 8.6E-118 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 SUPERFAMILY SSF53098 333 518 1.58E-54 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 Gene3D G3DSA:1.10.150.20 181 250 4.5E-26 T 28-03-2018 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 Gene3D G3DSA:3.30.420.10 320 542 5.6E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 SUPERFAMILY SSF56672 523 930 1.33E-156 T 28-03-2018 A6A12_RS14055 763d127656fca69e567784df5c43212d 930 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 9 170 4.2E-54 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 A6A12_RS09765 50c8a1d92ee473787770c909e79534e4 74 Pfam PF07208 Protein of unknown function (DUF1414) 26 69 3.2E-20 T 28-03-2018 IPR009857 Uncharacterised protein family UPF0352 A6A12_RS09765 50c8a1d92ee473787770c909e79534e4 74 SUPERFAMILY SSF158651 1 72 4.84E-28 T 28-03-2018 IPR023202 YejL-like domain A6A12_RS09765 50c8a1d92ee473787770c909e79534e4 74 Hamap MF_00816 UPF0352 protein YejL [yejL]. 1 71 22.843 T 28-03-2018 IPR009857 Uncharacterised protein family UPF0352 A6A12_RS09765 50c8a1d92ee473787770c909e79534e4 74 Gene3D G3DSA:1.10.3390.10 2 71 1.5E-30 T 28-03-2018 IPR023202 YejL-like domain A6A12_RS09765 50c8a1d92ee473787770c909e79534e4 74 ProDom PD027794 UPF0352 YEJL NTHI1007 CPS_2611 VF1649 VV1166 HD1515 VP2129 YPO1261/Y2923/YP0880 ECA2748 1 69 2.0E-27 T 28-03-2018 IPR009857 Uncharacterised protein family UPF0352 A6A12_RS09765 50c8a1d92ee473787770c909e79534e4 74 PIRSF PIRSF006188 1 72 6.7E-35 T 28-03-2018 IPR009857 Uncharacterised protein family UPF0352 A6A12_RS03485 deab8d6794f753d38355e56cc1cb4747 267 Pfam PF00459 Inositol monophosphatase family 2 258 6.7E-65 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A6A12_RS03485 deab8d6794f753d38355e56cc1cb4747 267 Gene3D G3DSA:3.30.540.10 1 149 3.9E-46 T 28-03-2018 A6A12_RS03485 deab8d6794f753d38355e56cc1cb4747 267 Gene3D G3DSA:3.40.190.80 150 265 1.2E-29 T 28-03-2018 A6A12_RS03485 deab8d6794f753d38355e56cc1cb4747 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 104 123 2.1E-34 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 A6A12_RS03485 deab8d6794f753d38355e56cc1cb4747 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 198 210 2.1E-34 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 A6A12_RS03485 deab8d6794f753d38355e56cc1cb4747 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 156 182 2.1E-34 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 A6A12_RS03485 deab8d6794f753d38355e56cc1cb4747 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 2.1E-34 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 A6A12_RS03485 deab8d6794f753d38355e56cc1cb4747 267 SUPERFAMILY SSF56655 1 259 4.45E-80 T 28-03-2018 A6A12_RS03485 deab8d6794f753d38355e56cc1cb4747 267 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site A6A12_RS03485 deab8d6794f753d38355e56cc1cb4747 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 2.6E-55 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A6A12_RS03485 deab8d6794f753d38355e56cc1cb4747 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 2.6E-55 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A6A12_RS03485 deab8d6794f753d38355e56cc1cb4747 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 2.6E-55 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A6A12_RS03485 deab8d6794f753d38355e56cc1cb4747 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 2.6E-55 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A6A12_RS03485 deab8d6794f753d38355e56cc1cb4747 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 2.6E-55 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A6A12_RS03485 deab8d6794f753d38355e56cc1cb4747 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 2.6E-55 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A6A12_RS00430 57a997e22b17f9cca9f80972ecc1e097 336 Pfam PF12146 Serine aminopeptidase, S33 54 311 2.2E-57 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 A6A12_RS00430 57a997e22b17f9cca9f80972ecc1e097 336 SUPERFAMILY SSF53474 35 318 9.4E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS00430 57a997e22b17f9cca9f80972ecc1e097 336 Gene3D G3DSA:3.40.50.1820 28 325 6.6E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS08915 ef1bb615882c850f8b229251d84664b7 246 Gene3D G3DSA:1.10.3720.10 3 246 9.7E-37 T 28-03-2018 A6A12_RS08915 ef1bb615882c850f8b229251d84664b7 246 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 241 7.4E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS08915 ef1bb615882c850f8b229251d84664b7 246 SUPERFAMILY SSF161098 11 78 3.01E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS08915 ef1bb615882c850f8b229251d84664b7 246 SUPERFAMILY SSF161098 110 233 3.01E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS08915 ef1bb615882c850f8b229251d84664b7 246 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 73 1.3E-15 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A6A12_RS01225 23aa8ab37969985909c1226454bbd5ad 510 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 5 509 1.2E-227 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS01225 23aa8ab37969985909c1226454bbd5ad 510 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 83 297 4.9E-81 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS01225 23aa8ab37969985909c1226454bbd5ad 510 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 5 510 49.56 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS01225 23aa8ab37969985909c1226454bbd5ad 510 SUPERFAMILY SSF64158 78 308 1.96E-81 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS01225 23aa8ab37969985909c1226454bbd5ad 510 Gene3D G3DSA:3.40.1450.10 78 299 2.0E-92 T 28-03-2018 A6A12_RS01225 23aa8ab37969985909c1226454bbd5ad 510 Pfam PF01676 Metalloenzyme superfamily 5 497 2.9E-82 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A6A12_RS01225 23aa8ab37969985909c1226454bbd5ad 510 PIRSF PIRSF001492 1 510 7.6E-203 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS01225 23aa8ab37969985909c1226454bbd5ad 510 Gene3D G3DSA:3.40.720.10 300 510 2.5E-35 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A6A12_RS01225 23aa8ab37969985909c1226454bbd5ad 510 SUPERFAMILY SSF53649 5 78 7.85E-77 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A6A12_RS01225 23aa8ab37969985909c1226454bbd5ad 510 SUPERFAMILY SSF53649 306 509 7.85E-77 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A6A12_RS05955 ebacf18cdb516a95c1df5e72fb0c4652 196 Gene3D G3DSA:1.10.340.30 16 196 8.0E-77 T 28-03-2018 A6A12_RS05955 ebacf18cdb516a95c1df5e72fb0c4652 196 Pfam PF03352 Methyladenine glycosylase 20 194 6.7E-73 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 A6A12_RS05955 ebacf18cdb516a95c1df5e72fb0c4652 196 SUPERFAMILY SSF48150 17 194 2.35E-72 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A6A12_RS11555 50c01c9310bf624826a8bee0abd002c2 576 Gene3D G3DSA:3.40.710.10 239 575 4.8E-81 T 28-03-2018 A6A12_RS11555 50c01c9310bf624826a8bee0abd002c2 576 Pfam PF00905 Penicillin binding protein transpeptidase domain 264 559 1.9E-75 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A6A12_RS11555 50c01c9310bf624826a8bee0abd002c2 576 Gene3D G3DSA:3.90.1310.10 39 238 4.0E-41 T 28-03-2018 A6A12_RS11555 50c01c9310bf624826a8bee0abd002c2 576 SUPERFAMILY SSF56519 66 237 2.88E-43 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A6A12_RS11555 50c01c9310bf624826a8bee0abd002c2 576 SUPERFAMILY SSF56601 190 569 1.21E-89 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A6A12_RS11555 50c01c9310bf624826a8bee0abd002c2 576 Pfam PF03717 Penicillin-binding Protein dimerisation domain 70 224 1.9E-17 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A6A12_RS07625 fccf211a25dd1ed06befeb0a73edfdf1 934 SUPERFAMILY SSF82171 323 565 3.53E-20 T 28-03-2018 A6A12_RS07625 fccf211a25dd1ed06befeb0a73edfdf1 934 Gene3D G3DSA:2.140.10.30 490 679 7.4E-7 T 28-03-2018 A6A12_RS07625 fccf211a25dd1ed06befeb0a73edfdf1 934 Gene3D G3DSA:2.140.10.30 282 489 1.2E-11 T 28-03-2018 A6A12_RS11765 81f92aa5b73ba0409f79621433341102 740 Gene3D G3DSA:3.30.70.260 661 739 1.2E-5 T 28-03-2018 A6A12_RS11765 81f92aa5b73ba0409f79621433341102 740 Pfam PF04607 Region found in RelA / SpoT proteins 250 359 1.7E-36 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 A6A12_RS11765 81f92aa5b73ba0409f79621433341102 740 SUPERFAMILY SSF81271 396 462 1.55E-20 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A6A12_RS11765 81f92aa5b73ba0409f79621433341102 740 Pfam PF02824 TGS domain 403 462 3.3E-21 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A6A12_RS11765 81f92aa5b73ba0409f79621433341102 740 Gene3D G3DSA:3.10.20.30 397 472 9.7E-23 T 28-03-2018 IPR012675 Beta-grasp domain A6A12_RS11765 81f92aa5b73ba0409f79621433341102 740 SUPERFAMILY SSF81301 195 407 1.57E-59 T 28-03-2018 A6A12_RS11765 81f92aa5b73ba0409f79621433341102 740 SUPERFAMILY SSF55021 663 738 5.5E-9 T 28-03-2018 A6A12_RS11765 81f92aa5b73ba0409f79621433341102 740 SMART SM00954 250 360 4.3E-64 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 A6A12_RS11765 81f92aa5b73ba0409f79621433341102 740 Pfam PF13291 ACT domain 662 738 1.2E-15 T 28-03-2018 IPR002912 ACT domain A6A12_RS11765 81f92aa5b73ba0409f79621433341102 740 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 64 738 6.2E-182 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 A6A12_RS11765 81f92aa5b73ba0409f79621433341102 740 Pfam PF13328 HD domain 57 190 2.9E-36 T 28-03-2018 IPR003607 HD/PDEase domain A6A12_RS11765 81f92aa5b73ba0409f79621433341102 740 Gene3D G3DSA:3.30.460.10 207 340 6.2E-42 T 28-03-2018 A6A12_RS11765 81f92aa5b73ba0409f79621433341102 740 SUPERFAMILY SSF109604 36 205 2.98E-43 T 28-03-2018 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 SUPERFAMILY SSF56719 395 561 1.54E-87 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 SUPERFAMILY SSF56719 731 796 1.54E-87 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 Gene3D G3DSA:3.40.50.670 403 802 3.9E-109 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 734 794 5.6E-30 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 173 3.8E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 SUPERFAMILY SSF55874 4 212 1.31E-74 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 ProSitePatterns PS00177 DNA topoisomerase II signature. 423 431 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR00418 DNA topoisomerase II family signature 35 50 2.8E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR00418 DNA topoisomerase II family signature 113 127 2.8E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR00418 DNA topoisomerase II family signature 737 753 2.8E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR00418 DNA topoisomerase II family signature 488 504 2.8E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR00418 DNA topoisomerase II family signature 70 83 2.8E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR00418 DNA topoisomerase II family signature 506 523 2.8E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR00418 DNA topoisomerase II family signature 526 538 2.8E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR00418 DNA topoisomerase II family signature 269 282 2.8E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR00418 DNA topoisomerase II family signature 421 435 2.8E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 Gene3D G3DSA:3.30.565.10 17 220 8.1E-74 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR01159 DNA gyrase subunit B signature 313 329 4.9E-87 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR01159 DNA gyrase subunit B signature 195 208 4.9E-87 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR01159 DNA gyrase subunit B signature 220 242 4.9E-87 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR01159 DNA gyrase subunit B signature 5 15 4.9E-87 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR01159 DNA gyrase subunit B signature 180 195 4.9E-87 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR01159 DNA gyrase subunit B signature 471 480 4.9E-87 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR01159 DNA gyrase subunit B signature 361 375 4.9E-87 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR01159 DNA gyrase subunit B signature 758 770 4.9E-87 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR01159 DNA gyrase subunit B signature 375 395 4.9E-87 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR01159 DNA gyrase subunit B signature 774 790 4.9E-87 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 PRINTS PR01159 DNA gyrase subunit B signature 243 261 4.9E-87 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 SMART SM00387 31 175 3.8E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 SMART SM00433 35 798 8.5E-263 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 Gene3D G3DSA:3.30.230.10 221 393 1.0E-62 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 Pfam PF00204 DNA gyrase B 221 391 3.0E-59 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 2 805 106.92 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 SUPERFAMILY SSF54211 221 393 1.04E-57 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 Pfam PF01751 Toprim domain 420 532 1.1E-18 T 28-03-2018 IPR006171 TOPRIM domain A6A12_RS00020 219d66e97da22453b4dab65f596dcda4 805 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 5 805 0.0 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 A6A12_RS02750 cfa73360cebe9fb8795c32e5e3caedb9 865 SUPERFAMILY SSF74778 2 160 5.36E-67 T 28-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 A6A12_RS02750 cfa73360cebe9fb8795c32e5e3caedb9 865 Gene3D G3DSA:3.40.1060.10 521 682 1.4E-29 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS02750 cfa73360cebe9fb8795c32e5e3caedb9 865 Pfam PF00330 Aconitase family (aconitate hydratase) 472 818 2.7E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS02750 cfa73360cebe9fb8795c32e5e3caedb9 865 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 853 0.0 T 28-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 A6A12_RS02750 cfa73360cebe9fb8795c32e5e3caedb9 865 Gene3D G3DSA:3.30.499.10 402 520 1.1E-10 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS02750 cfa73360cebe9fb8795c32e5e3caedb9 865 SUPERFAMILY SSF52016 163 372 2.35E-71 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A6A12_RS02750 cfa73360cebe9fb8795c32e5e3caedb9 865 Gene3D G3DSA:3.30.499.10 683 865 4.2E-51 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS02750 cfa73360cebe9fb8795c32e5e3caedb9 865 ProSitePatterns PS00450 Aconitase family signature 1. 702 719 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A6A12_RS02750 cfa73360cebe9fb8795c32e5e3caedb9 865 SUPERFAMILY SSF53732 379 859 1.7E-147 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS02750 cfa73360cebe9fb8795c32e5e3caedb9 865 Gene3D G3DSA:3.20.19.10 162 364 8.5E-35 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A6A12_RS02750 cfa73360cebe9fb8795c32e5e3caedb9 865 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 382 2.0E-99 T 28-03-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 A6A12_RS02750 cfa73360cebe9fb8795c32e5e3caedb9 865 PIRSF PIRSF036687 1 859 0.0 T 28-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 A6A12_RS02750 cfa73360cebe9fb8795c32e5e3caedb9 865 Pfam PF11791 Aconitate B N-terminal domain 4 156 3.7E-65 T 28-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 A6A12_RS02750 cfa73360cebe9fb8795c32e5e3caedb9 865 ProSitePatterns PS01244 Aconitase family signature 2. 761 774 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A6A12_RS09630 7d16af65f4d15f87a523c65785e5ed7b 226 SUPERFAMILY SSF56925 53 226 7.59E-19 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A6A12_RS09630 7d16af65f4d15f87a523c65785e5ed7b 226 Pfam PF13505 Outer membrane protein beta-barrel domain 41 193 6.8E-9 T 28-03-2018 IPR027385 Outer membrane protein beta-barrel A6A12_RS09630 7d16af65f4d15f87a523c65785e5ed7b 226 Gene3D G3DSA:2.40.160.20 46 226 3.4E-15 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A6A12_RS11620 5349014dc701e34e5e851ab43b6e76e8 198 Gene3D G3DSA:2.102.10.10 34 198 4.7E-40 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A6A12_RS11620 5349014dc701e34e5e851ab43b6e76e8 198 Gene3D G3DSA:1.20.5.510 6 33 2.9E-16 T 28-03-2018 A6A12_RS11620 5349014dc701e34e5e851ab43b6e76e8 198 Pfam PF00355 Rieske [2Fe-2S] domain 56 174 4.8E-12 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A6A12_RS11620 5349014dc701e34e5e851ab43b6e76e8 198 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 5 40 1.6E-14 T 28-03-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 A6A12_RS11620 5349014dc701e34e5e851ab43b6e76e8 198 PRINTS PR00162 Rieske 2Fe-2S subunit signature 162 174 9.4E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A6A12_RS11620 5349014dc701e34e5e851ab43b6e76e8 198 PRINTS PR00162 Rieske 2Fe-2S subunit signature 149 161 9.4E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A6A12_RS11620 5349014dc701e34e5e851ab43b6e76e8 198 PRINTS PR00162 Rieske 2Fe-2S subunit signature 119 130 9.4E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 A6A12_RS11620 5349014dc701e34e5e851ab43b6e76e8 198 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 9 190 8.8E-75 T 28-03-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 A6A12_RS11620 5349014dc701e34e5e851ab43b6e76e8 198 SUPERFAMILY SSF50022 30 193 2.91E-45 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 A6A12_RS07435 37fedf14af59a5ddceec1e1fffe42ba5 390 SMART SM00283 86 338 9.3E-13 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS07435 37fedf14af59a5ddceec1e1fffe42ba5 390 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 150 305 2.0E-27 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS07435 37fedf14af59a5ddceec1e1fffe42ba5 390 SUPERFAMILY SSF58104 99 339 3.92E-40 T 28-03-2018 A6A12_RS07435 37fedf14af59a5ddceec1e1fffe42ba5 390 Gene3D G3DSA:1.10.287.950 92 347 3.0E-34 T 28-03-2018 A6A12_RS11110 c66f0e3cecb0471fe26168c0cd0699ce 200 Gene3D G3DSA:1.10.1740.10 11 138 2.7E-21 T 28-03-2018 A6A12_RS11110 c66f0e3cecb0471fe26168c0cd0699ce 200 SUPERFAMILY SSF88946 13 124 3.85E-26 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS11110 c66f0e3cecb0471fe26168c0cd0699ce 200 Pfam PF04545 Sigma-70, region 4 148 193 3.5E-13 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS11110 c66f0e3cecb0471fe26168c0cd0699ce 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 193 8.3E-26 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS11110 c66f0e3cecb0471fe26168c0cd0699ce 200 Pfam PF04542 Sigma-70 region 2 39 105 5.2E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS11110 c66f0e3cecb0471fe26168c0cd0699ce 200 SUPERFAMILY SSF88659 133 195 1.59E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS11110 c66f0e3cecb0471fe26168c0cd0699ce 200 Gene3D G3DSA:1.10.10.10 139 199 2.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS14215 c3eb1c9c134b79e8545534321f3b9a58 418 Pfam PF07690 Major Facilitator Superfamily 36 374 3.0E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A6A12_RS14215 c3eb1c9c134b79e8545534321f3b9a58 418 Gene3D G3DSA:1.20.1250.20 21 219 9.3E-35 T 28-03-2018 A6A12_RS14215 c3eb1c9c134b79e8545534321f3b9a58 418 Gene3D G3DSA:1.20.1250.20 221 416 3.0E-10 T 28-03-2018 A6A12_RS14215 c3eb1c9c134b79e8545534321f3b9a58 418 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 30 380 5.8E-68 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 A6A12_RS14215 c3eb1c9c134b79e8545534321f3b9a58 418 ProSitePatterns PS00216 Sugar transport proteins signature 1. 86 102 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A6A12_RS14215 c3eb1c9c134b79e8545534321f3b9a58 418 SUPERFAMILY SSF103473 28 407 4.32E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain A6A12_RS06435 e10be817745e42a3da55f4056d61e07d 474 Gene3D G3DSA:3.90.79.10 33 199 2.1E-14 T 28-03-2018 A6A12_RS06435 e10be817745e42a3da55f4056d61e07d 474 SUPERFAMILY SSF55811 33 112 1.49E-17 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A6A12_RS06435 e10be817745e42a3da55f4056d61e07d 474 Pfam PF00293 NUDIX domain 36 102 6.7E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A6A12_RS06435 e10be817745e42a3da55f4056d61e07d 474 SUPERFAMILY SSF48317 189 357 1.57E-9 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A6A12_RS06435 e10be817745e42a3da55f4056d61e07d 474 PRINTS PR00502 NUDIX hydrolase family signature 57 71 6.5E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A6A12_RS06435 e10be817745e42a3da55f4056d61e07d 474 PRINTS PR00502 NUDIX hydrolase family signature 71 86 6.5E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A6A12_RS06435 e10be817745e42a3da55f4056d61e07d 474 Pfam PF01569 PAP2 superfamily 246 358 8.3E-8 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A6A12_RS06435 e10be817745e42a3da55f4056d61e07d 474 Gene3D G3DSA:1.20.144.10 200 365 1.3E-7 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A6A12_RS06435 e10be817745e42a3da55f4056d61e07d 474 ProSitePatterns PS00893 Nudix box signature. 62 83 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A6A12_RS02975 249be53b4fe747c6f1762afb21295ad8 138 Pfam PF02033 Ribosome-binding factor A 7 110 1.6E-30 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 A6A12_RS02975 249be53b4fe747c6f1762afb21295ad8 138 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 118 21.06 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 A6A12_RS02975 249be53b4fe747c6f1762afb21295ad8 138 ProSitePatterns PS01319 Ribosome-binding factor A signature. 77 98 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 A6A12_RS02975 249be53b4fe747c6f1762afb21295ad8 138 SUPERFAMILY SSF89919 2 105 1.11E-31 T 28-03-2018 IPR023799 Ribosome-binding factor A domain A6A12_RS02975 249be53b4fe747c6f1762afb21295ad8 138 Gene3D G3DSA:3.30.300.20 5 118 5.6E-33 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A6A12_RS02975 249be53b4fe747c6f1762afb21295ad8 138 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 116 1.2E-35 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 A6A12_RS02975 249be53b4fe747c6f1762afb21295ad8 138 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 98 4.0E-45 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 A6A12_RS09590 2e2279c315214e259f13744dc1a8bc55 197 SUPERFAMILY SSF144091 19 193 5.1E-30 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A6A12_RS09590 2e2279c315214e259f13744dc1a8bc55 197 TIGRFAM TIGR03902 rhom_GG_sort: rhombosortase 39 185 3.6E-51 T 28-03-2018 IPR023826 Rhomboid-like serine protease, proteobacteria A6A12_RS09590 2e2279c315214e259f13744dc1a8bc55 197 Gene3D G3DSA:1.20.1540.10 17 187 3.6E-20 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A6A12_RS09590 2e2279c315214e259f13744dc1a8bc55 197 Pfam PF01694 Rhomboid family 48 186 1.2E-14 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A6A12_RS03670 c6ffc0c9aed8ed85fe988983b0ff5246 258 TIGRFAM TIGR03580 EF_0832: conserved hypothetical protein EF_0832/AHA_3913 2 258 2.0E-147 T 28-03-2018 IPR020042 Protein of unknown function DUF4311 A6A12_RS03670 c6ffc0c9aed8ed85fe988983b0ff5246 258 Pfam PF14188 Domain of unknown function (DUF4311) 25 237 1.1E-118 T 28-03-2018 IPR020042 Protein of unknown function DUF4311 A6A12_RS05375 9dc1da1375a4e882bbcb305c11852cda 133 Pfam PF03061 Thioesterase superfamily 26 98 1.7E-20 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A6A12_RS05375 9dc1da1375a4e882bbcb305c11852cda 133 Gene3D G3DSA:3.10.129.10 1 133 2.2E-34 T 28-03-2018 A6A12_RS05375 9dc1da1375a4e882bbcb305c11852cda 133 SUPERFAMILY SSF54637 9 131 3.6E-38 T 28-03-2018 IPR029069 HotDog domain A6A12_RS06070 cb8bdbd28f95754ca70fed1d5b2f1926 219 Gene3D G3DSA:3.40.50.2300 1 120 8.5E-31 T 28-03-2018 A6A12_RS06070 cb8bdbd28f95754ca70fed1d5b2f1926 219 Pfam PF00072 Response regulator receiver domain 3 113 9.3E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS06070 cb8bdbd28f95754ca70fed1d5b2f1926 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 7.6E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS06070 cb8bdbd28f95754ca70fed1d5b2f1926 219 SMART SM00448 1 112 1.8E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS06070 cb8bdbd28f95754ca70fed1d5b2f1926 219 SMART SM00862 145 216 3.7E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS06070 cb8bdbd28f95754ca70fed1d5b2f1926 219 Gene3D G3DSA:1.10.10.10 121 219 9.5E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS06070 cb8bdbd28f95754ca70fed1d5b2f1926 219 SUPERFAMILY SSF52172 1 133 9.53E-37 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS06070 cb8bdbd28f95754ca70fed1d5b2f1926 219 SUPERFAMILY SSF46894 119 217 3.97E-27 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS11310 0f5863334b5c5c15d850a301163da92a 453 TIGRFAM TIGR02643 T_phosphoryl: thymidine phosphorylase 13 437 3.4E-211 T 28-03-2018 IPR013465 Thymidine phosphorylase GO:0006213|GO:0009032 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 A6A12_RS11310 0f5863334b5c5c15d850a301163da92a 453 SUPERFAMILY SSF54680 349 447 5.36E-28 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS11310 0f5863334b5c5c15d850a301163da92a 453 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 16 434 8.9E-159 T 28-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS11310 0f5863334b5c5c15d850a301163da92a 453 PIRSF PIRSF000478 12 449 4.5E-148 T 28-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS11310 0f5863334b5c5c15d850a301163da92a 453 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 124 139 - T 28-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS11310 0f5863334b5c5c15d850a301163da92a 453 Hamap MF_01628 Thymidine phosphorylase [deoA]. 13 448 45.101 T 28-03-2018 IPR013465 Thymidine phosphorylase GO:0006213|GO:0009032 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 A6A12_RS11310 0f5863334b5c5c15d850a301163da92a 453 Pfam PF00591 Glycosyl transferase family, a/b domain 91 320 1.3E-47 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS11310 0f5863334b5c5c15d850a301163da92a 453 SMART SM00941 361 435 3.2E-29 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS11310 0f5863334b5c5c15d850a301163da92a 453 SUPERFAMILY SSF47648 15 81 5.76E-21 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS11310 0f5863334b5c5c15d850a301163da92a 453 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 361 434 2.4E-24 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS11310 0f5863334b5c5c15d850a301163da92a 453 Gene3D G3DSA:1.20.970.10 14 78 1.2E-22 T 28-03-2018 A6A12_RS11310 0f5863334b5c5c15d850a301163da92a 453 SUPERFAMILY SSF52418 83 345 3.66E-88 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS11310 0f5863334b5c5c15d850a301163da92a 453 Pfam PF02885 Glycosyl transferase family, helical bundle domain 17 78 1.1E-19 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS11310 0f5863334b5c5c15d850a301163da92a 453 Gene3D G3DSA:3.90.1170.30 353 440 3.3E-26 T 28-03-2018 A6A12_RS11310 0f5863334b5c5c15d850a301163da92a 453 Gene3D G3DSA:3.40.1030.10 80 352 9.0E-82 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS09195 86c7560a54ff133ac1a9b3134814b2dd 316 Pfam PF13410 Glutathione S-transferase, C-terminal domain 192 263 3.5E-12 T 28-03-2018 A6A12_RS09195 86c7560a54ff133ac1a9b3134814b2dd 316 Gene3D G3DSA:1.20.1050.10 177 315 2.7E-43 T 28-03-2018 A6A12_RS09195 86c7560a54ff133ac1a9b3134814b2dd 316 Gene3D G3DSA:3.40.30.10 32 176 5.8E-36 T 28-03-2018 A6A12_RS09195 86c7560a54ff133ac1a9b3134814b2dd 316 Pfam PF13409 Glutathione S-transferase, N-terminal domain 56 146 1.9E-21 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 A6A12_RS09195 86c7560a54ff133ac1a9b3134814b2dd 316 SUPERFAMILY SSF52833 31 150 4.47E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS09195 86c7560a54ff133ac1a9b3134814b2dd 316 SUPERFAMILY SSF47616 167 311 1.2E-35 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like A6A12_RS09195 86c7560a54ff133ac1a9b3134814b2dd 316 PIRSF PIRSF015753 4 312 2.9E-134 T 28-03-2018 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 A6A12_RS13330 390bfbe8859353d12ee8593d0a1dbb8a 312 Gene3D G3DSA:3.90.550.10 1 216 4.1E-23 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13330 390bfbe8859353d12ee8593d0a1dbb8a 312 SUPERFAMILY SSF53448 2 205 3.04E-27 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13330 390bfbe8859353d12ee8593d0a1dbb8a 312 Pfam PF00535 Glycosyl transferase family 2 7 138 3.5E-21 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A6A12_RS08990 b44adaf688214fc80ff91d2b4ac47893 250 Pfam PF02348 Cytidylyltransferase 5 221 1.1E-67 T 28-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 A6A12_RS08990 b44adaf688214fc80ff91d2b4ac47893 250 Gene3D G3DSA:3.90.550.10 1 250 2.0E-51 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS08990 b44adaf688214fc80ff91d2b4ac47893 250 SUPERFAMILY SSF53448 3 246 4.51E-66 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS08990 b44adaf688214fc80ff91d2b4ac47893 250 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 1 241 8.2E-116 T 28-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 A6A12_RS08990 b44adaf688214fc80ff91d2b4ac47893 250 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 248 46.801 T 28-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 A6A12_RS03170 99a2702ae54cd155a74380e4283d2058 296 Gene3D G3DSA:3.40.190.10 88 183 4.9E-4 T 28-03-2018 A6A12_RS03170 99a2702ae54cd155a74380e4283d2058 296 Pfam PF03466 LysR substrate binding domain 96 288 2.8E-12 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS03170 99a2702ae54cd155a74380e4283d2058 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.2E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS03170 99a2702ae54cd155a74380e4283d2058 296 SUPERFAMILY SSF46785 2 85 3.35E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03170 99a2702ae54cd155a74380e4283d2058 296 SUPERFAMILY SSF53850 90 288 3.5E-24 T 28-03-2018 A6A12_RS03170 99a2702ae54cd155a74380e4283d2058 296 Gene3D G3DSA:3.40.190.10 184 253 6.2E-4 T 28-03-2018 A6A12_RS03170 99a2702ae54cd155a74380e4283d2058 296 Gene3D G3DSA:1.10.10.10 2 85 2.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09650 838298c3bbc605fafd30d3b28dc58eeb 261 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A6A12_RS09650 838298c3bbc605fafd30d3b28dc58eeb 261 Pfam PF01026 TatD related DNase 3 253 1.8E-75 T 28-03-2018 IPR001130 TatD family GO:0016788 A6A12_RS09650 838298c3bbc605fafd30d3b28dc58eeb 261 Gene3D G3DSA:3.20.20.140 1 259 4.5E-78 T 28-03-2018 A6A12_RS09650 838298c3bbc605fafd30d3b28dc58eeb 261 PIRSF PIRSF005902 1 258 1.3E-79 T 28-03-2018 IPR001130 TatD family GO:0016788 A6A12_RS09650 838298c3bbc605fafd30d3b28dc58eeb 261 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 9.4E-90 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A6A12_RS09650 838298c3bbc605fafd30d3b28dc58eeb 261 SUPERFAMILY SSF51556 1 253 4.84E-86 T 28-03-2018 IPR032466 Metal-dependent hydrolase A6A12_RS09650 838298c3bbc605fafd30d3b28dc58eeb 261 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 190 206 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A6A12_RS09060 c4c628a5c3a4cb55f65b478b80529385 180 SUPERFAMILY SSF53474 2 176 1.24E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS09060 c4c628a5c3a4cb55f65b478b80529385 180 Hamap MF_01047 UPF0227 protein YcfP [ycfP]. 1 178 48.147 T 28-03-2018 IPR022987 Uncharacterised protein family UPF0227 A6A12_RS09060 c4c628a5c3a4cb55f65b478b80529385 180 Pfam PF05728 Uncharacterised protein family (UPF0227) 1 177 6.9E-69 T 28-03-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA A6A12_RS10485 4dd9b5b57167496dd657043159df3557 419 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 3 395 4.7E-112 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A6A12_RS10485 4dd9b5b57167496dd657043159df3557 419 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 319 339 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A6A12_RS10485 4dd9b5b57167496dd657043159df3557 419 Pfam PF00860 Permease family 3 371 2.5E-92 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A6A12_RS03860 52837ccbbcf256934a5ca7fea76e9aba 161 Hamap MF_00023 SsrA-binding protein [smpB]. 1 161 70.096 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 A6A12_RS03860 52837ccbbcf256934a5ca7fea76e9aba 161 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 15 139 4.0E-57 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 A6A12_RS03860 52837ccbbcf256934a5ca7fea76e9aba 161 ProSitePatterns PS01317 SsrA-binding protein. 33 45 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site A6A12_RS03860 52837ccbbcf256934a5ca7fea76e9aba 161 TIGRFAM TIGR00086 smpB: SsrA-binding protein 15 157 5.6E-54 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 A6A12_RS03860 52837ccbbcf256934a5ca7fea76e9aba 161 SUPERFAMILY SSF74982 9 139 6.28E-49 T 28-03-2018 IPR023620 Small protein B A6A12_RS03860 52837ccbbcf256934a5ca7fea76e9aba 161 Pfam PF01668 SmpB protein 15 157 9.2E-57 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 A6A12_RS03860 52837ccbbcf256934a5ca7fea76e9aba 161 Gene3D G3DSA:2.40.280.10 15 134 3.6E-45 T 28-03-2018 IPR023620 Small protein B A6A12_RS03630 7950debb7c34ec8d1ebfece3cc8a5624 628 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 50 502 4.6E-148 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A6A12_RS03630 7950debb7c34ec8d1ebfece3cc8a5624 628 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 13 502 2.4E-158 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A6A12_RS03630 7950debb7c34ec8d1ebfece3cc8a5624 628 ProSitePatterns PS01303 BCCT family of transporters signature. 321 330 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 A6A12_RS02740 356548fb5e6d40cd5183c301c51690ee 782 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 40 762 0.0 T 28-03-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A6A12_RS02740 356548fb5e6d40cd5183c301c51690ee 782 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 185 719 1.9E-153 T 28-03-2018 A6A12_RS02740 356548fb5e6d40cd5183c301c51690ee 782 Pfam PF00905 Penicillin binding protein transpeptidase domain 444 682 1.0E-21 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A6A12_RS02740 356548fb5e6d40cd5183c301c51690ee 782 SUPERFAMILY SSF56601 384 765 9.68E-108 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A6A12_RS02740 356548fb5e6d40cd5183c301c51690ee 782 SUPERFAMILY SSF56601 334 356 9.68E-108 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A6A12_RS02740 356548fb5e6d40cd5183c301c51690ee 782 Pfam PF14814 Bifunctional transglycosylase second domain 85 168 1.1E-24 T 28-03-2018 IPR028166 Bifunctional transglycosylase second domain KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A6A12_RS02740 356548fb5e6d40cd5183c301c51690ee 782 PIRSF PIRSF002799 5 782 0.0 T 28-03-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A6A12_RS02740 356548fb5e6d40cd5183c301c51690ee 782 Gene3D G3DSA:1.10.3810.10 184 377 3.3E-67 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 A6A12_RS02740 356548fb5e6d40cd5183c301c51690ee 782 Gene3D G3DSA:1.20.5.100 16 67 1.7E-12 T 28-03-2018 A6A12_RS02740 356548fb5e6d40cd5183c301c51690ee 782 Pfam PF00912 Transglycosylase 181 352 1.9E-59 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 A6A12_RS02740 356548fb5e6d40cd5183c301c51690ee 782 SUPERFAMILY SSF53955 176 376 4.5E-69 T 28-03-2018 IPR023346 Lysozyme-like domain A6A12_RS02740 356548fb5e6d40cd5183c301c51690ee 782 Gene3D G3DSA:3.40.710.10 378 771 4.0E-93 T 28-03-2018 A6A12_RS02740 356548fb5e6d40cd5183c301c51690ee 782 Gene3D G3DSA:3.30.2060.10 84 171 1.3E-26 T 28-03-2018 A6A12_RS07525 d358bdc57c32b7ff9dc0a936b6bf882c 298 Gene3D G3DSA:3.30.420.40 1 114 2.6E-22 T 28-03-2018 A6A12_RS07525 d358bdc57c32b7ff9dc0a936b6bf882c 298 SUPERFAMILY SSF53067 1 297 9.48E-60 T 28-03-2018 A6A12_RS07525 d358bdc57c32b7ff9dc0a936b6bf882c 298 Pfam PF00480 ROK family 3 295 9.8E-75 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A6A12_RS07525 d358bdc57c32b7ff9dc0a936b6bf882c 298 ProSitePatterns PS01125 ROK family signature. 129 156 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A6A12_RS07525 d358bdc57c32b7ff9dc0a936b6bf882c 298 Gene3D G3DSA:3.30.420.40 115 298 3.9E-46 T 28-03-2018 A6A12_RS09920 c576f7959a6821c1663aa2b1afe3c159 295 PIRSF PIRSF003092 7 288 2.7E-84 T 28-03-2018 IPR025501 ATP binding protein MinD A6A12_RS09920 c576f7959a6821c1663aa2b1afe3c159 295 SUPERFAMILY SSF52540 22 282 1.52E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09920 c576f7959a6821c1663aa2b1afe3c159 295 Gene3D G3DSA:3.40.50.300 21 265 3.9E-48 T 28-03-2018 A6A12_RS09920 c576f7959a6821c1663aa2b1afe3c159 295 Pfam PF13614 AAA domain 22 181 3.7E-18 T 28-03-2018 IPR025669 AAA domain A6A12_RS13545 a11ea6ac8025042865fd45f291fda8b3 213 Gene3D G3DSA:3.40.50.2020 1 193 2.1E-49 T 28-03-2018 A6A12_RS13545 a11ea6ac8025042865fd45f291fda8b3 213 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 10 187 3.5E-70 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS13545 a11ea6ac8025042865fd45f291fda8b3 213 SUPERFAMILY SSF53271 2 212 3.69E-50 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A6A12_RS13545 a11ea6ac8025042865fd45f291fda8b3 213 Pfam PF00156 Phosphoribosyl transferase domain 43 161 2.4E-12 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A6A12_RS13545 a11ea6ac8025042865fd45f291fda8b3 213 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 213 36.376 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS11850 395a93b12baeedf71a32378ea0262d6e 323 Gene3D G3DSA:3.30.70.1400 29 233 1.4E-22 T 28-03-2018 A6A12_RS11850 395a93b12baeedf71a32378ea0262d6e 323 Pfam PF01571 Aminomethyltransferase folate-binding domain 28 136 6.7E-7 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal A6A12_RS11850 395a93b12baeedf71a32378ea0262d6e 323 SUPERFAMILY SSF103025 18 235 3.61E-54 T 28-03-2018 A6A12_RS11850 395a93b12baeedf71a32378ea0262d6e 323 Hamap MF_01175 tRNA-modifying protein YgfZ [ygfZ]. 1 317 41.616 T 28-03-2018 IPR023758 tRNA-modifying protein YgfZ GO:0005542|GO:0009451 A6A12_RS11850 395a93b12baeedf71a32378ea0262d6e 323 PIRSF PIRSF006487 21 144 4.4E-6 T 28-03-2018 A6A12_RS11850 395a93b12baeedf71a32378ea0262d6e 323 PIRSF PIRSF006487 160 267 0.67 T 28-03-2018 A6A12_RS11850 395a93b12baeedf71a32378ea0262d6e 323 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 181 245 1.3E-24 T 28-03-2018 IPR017703 YgfZ/GcvT conserved site A6A12_RS11850 395a93b12baeedf71a32378ea0262d6e 323 SUPERFAMILY SSF101790 237 320 1.83E-17 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain A6A12_RS06650 f565565912427dbff2931be91eb3562d 57 Hamap MF_00919 Ribosome modulation factor [rmf]. 1 55 30.017 T 28-03-2018 IPR007040 Ribosome modulation factor A6A12_RS06650 f565565912427dbff2931be91eb3562d 57 Gene3D G3DSA:1.10.10.620 3 54 1.1E-25 T 28-03-2018 A6A12_RS06650 f565565912427dbff2931be91eb3562d 57 Pfam PF04957 Ribosome modulation factor 1 54 4.6E-28 T 28-03-2018 IPR007040 Ribosome modulation factor A6A12_RS06650 f565565912427dbff2931be91eb3562d 57 ProDom PD051650 RIBOSOME MODULATION FACTOR E FACTOR-RELATED DIMERIZATION BIOGENESIS RIBOSOMES INVOLVED 70S 1 51 6.0E-21 T 28-03-2018 IPR007040 Ribosome modulation factor A6A12_RS05935 8cb6deec2fdaf01c4e98d186703f6a6e 362 SMART SM00382 52 204 4.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS05935 8cb6deec2fdaf01c4e98d186703f6a6e 362 SUPERFAMILY SSF46689 246 355 1.61E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS05935 8cb6deec2fdaf01c4e98d186703f6a6e 362 Pfam PF00158 Sigma-54 interaction domain 33 195 6.7E-57 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A6A12_RS05935 8cb6deec2fdaf01c4e98d186703f6a6e 362 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 118 133 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A6A12_RS05935 8cb6deec2fdaf01c4e98d186703f6a6e 362 SUPERFAMILY SSF52540 33 266 1.05E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05935 8cb6deec2fdaf01c4e98d186703f6a6e 362 Pfam PF02954 Bacterial regulatory protein, Fis family 315 348 1.8E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS05935 8cb6deec2fdaf01c4e98d186703f6a6e 362 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 246 255 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A6A12_RS05935 8cb6deec2fdaf01c4e98d186703f6a6e 362 Gene3D G3DSA:1.10.10.60 327 357 3.0E-5 T 28-03-2018 A6A12_RS05935 8cb6deec2fdaf01c4e98d186703f6a6e 362 TIGRFAM TIGR02974 phageshock_pspF: psp operon transcriptional activator 32 354 1.3E-158 T 28-03-2018 IPR014317 Transcription activator PspF A6A12_RS05935 8cb6deec2fdaf01c4e98d186703f6a6e 362 Gene3D G3DSA:3.40.50.300 25 203 4.4E-27 T 28-03-2018 A6A12_RS05935 8cb6deec2fdaf01c4e98d186703f6a6e 362 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 337 357 1.0E-6 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS05935 8cb6deec2fdaf01c4e98d186703f6a6e 362 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 320 337 1.0E-6 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS05935 8cb6deec2fdaf01c4e98d186703f6a6e 362 Gene3D G3DSA:1.10.8.60 204 326 8.6E-21 T 28-03-2018 A6A12_RS01475 eca57ce5a2d226c3907ac8c86b2bb21c 250 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 53 223 7.7E-48 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 A6A12_RS01475 eca57ce5a2d226c3907ac8c86b2bb21c 250 TIGRFAM TIGR02057 PAPS_reductase: phosphoadenosine phosphosulfate reductase 25 246 3.9E-89 T 28-03-2018 IPR011800 Phosphoadenosine phosphosulphate reductase CysH GO:0004604|GO:0019379 KEGG: 00920+1.8.4.8 A6A12_RS01475 eca57ce5a2d226c3907ac8c86b2bb21c 250 Gene3D G3DSA:3.40.50.620 13 250 6.4E-39 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS01475 eca57ce5a2d226c3907ac8c86b2bb21c 250 PIRSF PIRSF000857 8 250 1.1E-54 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A6A12_RS01475 eca57ce5a2d226c3907ac8c86b2bb21c 250 SUPERFAMILY SSF52402 26 212 5.44E-53 T 28-03-2018 A6A12_RS01475 eca57ce5a2d226c3907ac8c86b2bb21c 250 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 37 247 3.6E-84 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A6A12_RS01475 eca57ce5a2d226c3907ac8c86b2bb21c 250 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 13 247 38.595 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 A6A12_RS11465 2149dd71de1ba231654dc2be9aa2771c 259 Pfam PF01925 Sulfite exporter TauE/SafE 12 246 2.6E-41 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A6A12_RS12485 0942fb583d166800d58f8d5a44dfc979 92 PIRSF PIRSF002144 1 92 5.2E-32 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12485 0942fb583d166800d58f8d5a44dfc979 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.79 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12485 0942fb583d166800d58f8d5a44dfc979 92 Pfam PF00203 Ribosomal protein S19 3 83 1.5E-36 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12485 0942fb583d166800d58f8d5a44dfc979 92 Gene3D G3DSA:3.30.860.10 1 92 7.7E-41 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12485 0942fb583d166800d58f8d5a44dfc979 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 6.6E-25 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12485 0942fb583d166800d58f8d5a44dfc979 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 6.6E-25 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12485 0942fb583d166800d58f8d5a44dfc979 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 6.6E-25 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12485 0942fb583d166800d58f8d5a44dfc979 92 SUPERFAMILY SSF54570 3 84 9.55E-36 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12485 0942fb583d166800d58f8d5a44dfc979 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12485 0942fb583d166800d58f8d5a44dfc979 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 1.2E-46 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 A6A12_RS05450 f479363c8f2b3b1501a20baeaa51279a 501 SUPERFAMILY SSF55073 79 225 2.04E-24 T 28-03-2018 IPR029787 Nucleotide cyclase A6A12_RS05450 f479363c8f2b3b1501a20baeaa51279a 501 Gene3D G3DSA:3.20.20.450 238 499 2.3E-84 T 28-03-2018 IPR001633 EAL domain A6A12_RS05450 f479363c8f2b3b1501a20baeaa51279a 501 Gene3D G3DSA:3.30.70.270 69 237 2.4E-30 T 28-03-2018 A6A12_RS05450 f479363c8f2b3b1501a20baeaa51279a 501 Pfam PF00563 EAL domain 247 481 5.9E-66 T 28-03-2018 IPR001633 EAL domain A6A12_RS05450 f479363c8f2b3b1501a20baeaa51279a 501 SMART SM00267 63 230 3.3E-19 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS05450 f479363c8f2b3b1501a20baeaa51279a 501 SUPERFAMILY SSF141868 247 495 2.75E-78 T 28-03-2018 IPR001633 EAL domain A6A12_RS05450 f479363c8f2b3b1501a20baeaa51279a 501 SMART SM00052 240 486 1.8E-82 T 28-03-2018 IPR001633 EAL domain A6A12_RS05450 f479363c8f2b3b1501a20baeaa51279a 501 Pfam PF00990 Diguanylate cyclase, GGDEF domain 75 225 8.7E-25 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS05450 f479363c8f2b3b1501a20baeaa51279a 501 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 70 225 2.5E-17 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS08005 4fe3d904d19566ca9867ce65753c7ab2 251 SUPERFAMILY SSF52540 16 228 1.66E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS08005 4fe3d904d19566ca9867ce65753c7ab2 251 Gene3D G3DSA:3.40.50.300 11 245 4.2E-43 T 28-03-2018 A6A12_RS08005 4fe3d904d19566ca9867ce65753c7ab2 251 Pfam PF00005 ABC transporter 15 164 1.3E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS08005 4fe3d904d19566ca9867ce65753c7ab2 251 SMART SM00382 22 213 6.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS08005 4fe3d904d19566ca9867ce65753c7ab2 251 Hamap MF_01005 Vitamin B12 import ATP-binding protein BtuD [btuD]. 1 251 44.251 T 28-03-2018 IPR023693 ABC transporter, vitamin B12, BtuD GO:0005524|GO:0015889|GO:0016887 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 2.6E-39 T 28-03-2018 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 2.6E-39 T 28-03-2018 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 2.6E-39 T 28-03-2018 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 2.6E-39 T 28-03-2018 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 2.6E-39 T 28-03-2018 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 313 6.9E-124 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 300 6.1E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 Gene3D G3DSA:3.40.50.720 144 318 4.6E-23 T 28-03-2018 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 Gene3D G3DSA:3.50.50.60 2 137 3.4E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 SUPERFAMILY SSF51905 2 313 1.14E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 2.1E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 2.1E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 2.1E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 2.1E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 2.1E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 2.1E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 2.1E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 2.1E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A6A12_RS05485 c2c9c91531009834306feebbf5cdafcd 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 2.1E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A6A12_RS10180 9fd4d9b49e60178356ad0332724654a4 136 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 56 126 1.8E-24 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) A6A12_RS10180 9fd4d9b49e60178356ad0332724654a4 136 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 54 128 3.2E-33 T 28-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 A6A12_RS10180 9fd4d9b49e60178356ad0332724654a4 136 Gene3D G3DSA:2.30.330.10 44 136 6.0E-30 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) A6A12_RS10180 9fd4d9b49e60178356ad0332724654a4 136 PRINTS PR00956 Flagellar motor switch protein FliN signature 73 89 1.1E-27 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A6A12_RS10180 9fd4d9b49e60178356ad0332724654a4 136 PRINTS PR00956 Flagellar motor switch protein FliN signature 56 72 1.1E-27 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A6A12_RS10180 9fd4d9b49e60178356ad0332724654a4 136 PRINTS PR00956 Flagellar motor switch protein FliN signature 102 117 1.1E-27 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A6A12_RS10180 9fd4d9b49e60178356ad0332724654a4 136 PRINTS PR00956 Flagellar motor switch protein FliN signature 89 102 1.1E-27 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 A6A12_RS10180 9fd4d9b49e60178356ad0332724654a4 136 SUPERFAMILY SSF101801 54 134 6.02E-25 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) A6A12_RS04655 8310e3582f2d8947c680573d7fc994e2 776 Pfam PF12838 4Fe-4S dicluster domain 377 430 9.8E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A6A12_RS04655 8310e3582f2d8947c680573d7fc994e2 776 SUPERFAMILY SSF46548 336 445 1.24E-20 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A6A12_RS04655 8310e3582f2d8947c680573d7fc994e2 776 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 417 428 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A6A12_RS04655 8310e3582f2d8947c680573d7fc994e2 776 Gene3D G3DSA:3.30.70.20 341 383 0.0054 T 28-03-2018 A6A12_RS04655 8310e3582f2d8947c680573d7fc994e2 776 Gene3D G3DSA:3.30.70.20 384 493 7.4E-16 T 28-03-2018 A6A12_RS04655 8310e3582f2d8947c680573d7fc994e2 776 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 774 251.591 T 28-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 A6A12_RS04655 8310e3582f2d8947c680573d7fc994e2 776 SUPERFAMILY SSF142019 95 302 4.71E-61 T 28-03-2018 A6A12_RS04655 8310e3582f2d8947c680573d7fc994e2 776 Gene3D G3DSA:2.40.50.100 26 128 0.0029 T 28-03-2018 A6A12_RS04655 8310e3582f2d8947c680573d7fc994e2 776 Pfam PF10531 SLBB domain 296 345 3.9E-11 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A6A12_RS04655 8310e3582f2d8947c680573d7fc994e2 776 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 140 283 2.1E-48 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A6A12_RS04655 8310e3582f2d8947c680573d7fc994e2 776 Pfam PF13375 RnfC Barrel sandwich hybrid domain 14 116 1.4E-35 T 28-03-2018 IPR026902 RnfC Barrel sandwich hybrid domain A6A12_RS04655 8310e3582f2d8947c680573d7fc994e2 776 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 13 447 4.6E-195 T 28-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 A6A12_RS02315 5f3af6a961a27beaacdc8220e4bb98eb 473 Pfam PF07804 HipA-like C-terminal domain 150 422 5.8E-43 T 28-03-2018 IPR012893 HipA-like, C-terminal A6A12_RS02315 5f3af6a961a27beaacdc8220e4bb98eb 473 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 30 110 4.4E-12 T 28-03-2018 IPR017508 HipA, N-terminal subdomain 1 A6A12_RS02315 5f3af6a961a27beaacdc8220e4bb98eb 473 Pfam PF13657 HipA N-terminal domain 12 111 2.0E-16 T 28-03-2018 IPR017508 HipA, N-terminal subdomain 1 A6A12_RS11300 894721e364af9bb135c464b8437115e2 239 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 5 234 3.4E-119 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 A6A12_RS11300 894721e364af9bb135c464b8437115e2 239 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 2 235 51.457 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 A6A12_RS11300 894721e364af9bb135c464b8437115e2 239 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 62 77 - T 28-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS11300 894721e364af9bb135c464b8437115e2 239 Pfam PF01048 Phosphorylase superfamily 15 222 1.9E-40 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A6A12_RS11300 894721e364af9bb135c464b8437115e2 239 SUPERFAMILY SSF53167 3 235 8.9E-93 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A6A12_RS11300 894721e364af9bb135c464b8437115e2 239 Gene3D G3DSA:3.40.50.1580 9 235 1.2E-54 T 28-03-2018 A6A12_RS10605 ca7ce0b98028f33dfd78bb978d7099b0 624 PRINTS PR01005 Flagellar hook-associated protein signature 125 145 3.7E-9 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A6A12_RS10605 ca7ce0b98028f33dfd78bb978d7099b0 624 PRINTS PR01005 Flagellar hook-associated protein signature 12 35 3.7E-9 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A6A12_RS10605 ca7ce0b98028f33dfd78bb978d7099b0 624 PRINTS PR01005 Flagellar hook-associated protein signature 158 182 3.7E-9 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A6A12_RS10605 ca7ce0b98028f33dfd78bb978d7099b0 624 PRINTS PR01005 Flagellar hook-associated protein signature 406 423 3.7E-9 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A6A12_RS10605 ca7ce0b98028f33dfd78bb978d7099b0 624 PRINTS PR01005 Flagellar hook-associated protein signature 50 72 3.7E-9 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A6A12_RS10605 ca7ce0b98028f33dfd78bb978d7099b0 624 SUPERFAMILY SSF64518 168 360 2.35E-24 T 28-03-2018 A6A12_RS10605 ca7ce0b98028f33dfd78bb978d7099b0 624 SUPERFAMILY SSF64518 433 623 2.35E-24 T 28-03-2018 A6A12_RS10605 ca7ce0b98028f33dfd78bb978d7099b0 624 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 578 623 1.7E-9 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A6A12_RS10605 ca7ce0b98028f33dfd78bb978d7099b0 624 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 5 335 3.1E-60 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 A6A12_RS14255 7c8f3c953f7170b7351d6418b8140792 649 Pfam PF13667 ThiC-associated domain 22 104 2.3E-32 T 28-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A6A12_RS14255 7c8f3c953f7170b7351d6418b8140792 649 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 143 594 1.3E-217 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A6A12_RS14255 7c8f3c953f7170b7351d6418b8140792 649 Pfam PF01964 Radical SAM ThiC family 144 592 3.5E-198 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A6A12_RS14255 7c8f3c953f7170b7351d6418b8140792 649 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 143 597 56.14 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A6A12_RS12075 bd00b5a72b4ba3ea7b3bea9b95b225c8 129 Pfam PF01042 Endoribonuclease L-PSP 8 127 1.8E-43 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family A6A12_RS12075 bd00b5a72b4ba3ea7b3bea9b95b225c8 129 Gene3D G3DSA:3.30.1330.40 1 129 4.0E-45 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A6A12_RS12075 bd00b5a72b4ba3ea7b3bea9b95b225c8 129 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 104 122 - T 28-03-2018 IPR019897 RidA, conserved site A6A12_RS12075 bd00b5a72b4ba3ea7b3bea9b95b225c8 129 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 127 7.5E-52 T 28-03-2018 IPR006056 RidA family A6A12_RS12075 bd00b5a72b4ba3ea7b3bea9b95b225c8 129 SUPERFAMILY SSF55298 2 128 4.24E-43 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A6A12_RS07970 a210d87125594d1c3a7b6c3496b11296 344 SUPERFAMILY SSF53335 62 332 1.94E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS07970 a210d87125594d1c3a7b6c3496b11296 344 Gene3D G3DSA:3.40.50.150 57 332 1.5E-51 T 28-03-2018 A6A12_RS07970 a210d87125594d1c3a7b6c3496b11296 344 Pfam PF05971 Protein of unknown function (DUF890) 22 332 2.2E-133 T 28-03-2018 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 A6A12_RS07970 a210d87125594d1c3a7b6c3496b11296 344 PIRSF PIRSF029038 13 344 1.6E-151 T 28-03-2018 IPR016909 Ribosomal RNA large subunit methyltransferase F GO:0005737|GO:0006364|GO:0008988 A6A12_RS07970 a210d87125594d1c3a7b6c3496b11296 344 Hamap MF_01848 Ribosomal RNA large subunit methyltransferase F [rlmF]. 24 334 54.28 T 28-03-2018 IPR016909 Ribosomal RNA large subunit methyltransferase F GO:0005737|GO:0006364|GO:0008988 A6A12_RS04920 8e33ff03025dea7388a764d30e515344 199 TIGRFAM TIGR00615 recR: recombination protein RecR 3 197 5.7E-78 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A6A12_RS04920 8e33ff03025dea7388a764d30e515344 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 199 103.575 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 A6A12_RS04920 8e33ff03025dea7388a764d30e515344 199 SMART SM00493 81 166 1.9E-16 T 28-03-2018 IPR006171 TOPRIM domain A6A12_RS04920 8e33ff03025dea7388a764d30e515344 199 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 28-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 A6A12_RS04920 8e33ff03025dea7388a764d30e515344 199 SUPERFAMILY SSF111304 2 199 3.53E-72 T 28-03-2018 IPR023627 Recombination protein RecR A6A12_RS04920 8e33ff03025dea7388a764d30e515344 199 Pfam PF13662 Toprim domain 82 172 4.1E-23 T 28-03-2018 IPR006171 TOPRIM domain A6A12_RS04920 8e33ff03025dea7388a764d30e515344 199 Pfam PF02132 RecR protein 41 77 5.7E-16 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger A6A12_RS04920 8e33ff03025dea7388a764d30e515344 199 Gene3D G3DSA:3.40.1360.10 78 171 1.4E-34 T 28-03-2018 A6A12_RS05205 57df9502f0a2ab386f9b8a0bc61a6c17 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 6.3E-21 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS05205 57df9502f0a2ab386f9b8a0bc61a6c17 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 6.3E-21 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS05205 57df9502f0a2ab386f9b8a0bc61a6c17 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 6.3E-21 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS05205 57df9502f0a2ab386f9b8a0bc61a6c17 90 Gene3D G3DSA:4.10.520.10 1 90 2.4E-34 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A6A12_RS05205 57df9502f0a2ab386f9b8a0bc61a6c17 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A6A12_RS05205 57df9502f0a2ab386f9b8a0bc61a6c17 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 9.5E-34 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS05205 57df9502f0a2ab386f9b8a0bc61a6c17 90 SMART SM00411 1 90 3.3E-44 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS05205 57df9502f0a2ab386f9b8a0bc61a6c17 90 SUPERFAMILY SSF47729 1 90 3.97E-32 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A6A12_RS12645 ca10f264f1a6e8fa704a23bed6e587e9 254 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 41 248 8.3E-10 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS12645 ca10f264f1a6e8fa704a23bed6e587e9 254 SUPERFAMILY SSF53850 22 252 5.43E-25 T 28-03-2018 A6A12_RS12645 ca10f264f1a6e8fa704a23bed6e587e9 254 Gene3D G3DSA:3.40.190.10 145 248 0.0097 T 28-03-2018 A6A12_RS12645 ca10f264f1a6e8fa704a23bed6e587e9 254 Gene3D G3DSA:3.40.190.10 13 144 1.2E-10 T 28-03-2018 A6A12_RS02985 54b4e06258e5ab8037ee357a16a3ecf9 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 20.998 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02985 54b4e06258e5ab8037ee357a16a3ecf9 89 Pfam PF00312 Ribosomal protein S15 8 88 2.6E-35 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS02985 54b4e06258e5ab8037ee357a16a3ecf9 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS02985 54b4e06258e5ab8037ee357a16a3ecf9 89 SMART SM01387 8 88 9.3E-51 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS02985 54b4e06258e5ab8037ee357a16a3ecf9 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 4.0E-26 T 28-03-2018 A6A12_RS02985 54b4e06258e5ab8037ee357a16a3ecf9 89 Gene3D G3DSA:1.10.287.10 2 89 1.6E-33 T 28-03-2018 A6A12_RS02985 54b4e06258e5ab8037ee357a16a3ecf9 89 SUPERFAMILY SSF47060 3 89 4.41E-34 T 28-03-2018 IPR009068 S15/NS1, RNA-binding A6A12_RS02985 54b4e06258e5ab8037ee357a16a3ecf9 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 3.1E-37 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01675 534594bfb50ccf95a28c1749f134829f 489 SUPERFAMILY SSF50249 39 128 1.35E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS01675 534594bfb50ccf95a28c1749f134829f 489 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 426 3.9E-172 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 A6A12_RS01675 534594bfb50ccf95a28c1749f134829f 489 Pfam PF10150 Ribonuclease E/G family 124 393 3.1E-102 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 A6A12_RS01675 534594bfb50ccf95a28c1749f134829f 489 Pfam PF00575 S1 RNA binding domain 38 109 5.7E-6 T 28-03-2018 IPR003029 S1 domain GO:0003676 A6A12_RS01675 534594bfb50ccf95a28c1749f134829f 489 Gene3D G3DSA:2.40.50.140 32 127 6.4E-31 T 28-03-2018 A6A12_RS01675 534594bfb50ccf95a28c1749f134829f 489 SMART SM00316 37 122 5.8E-10 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS04630 4db9dd3071b47d7535ec92c0a209db7b 138 Gene3D G3DSA:3.10.180.10 5 138 1.4E-37 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A6A12_RS04630 4db9dd3071b47d7535ec92c0a209db7b 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 126 1.2E-23 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A6A12_RS04630 4db9dd3071b47d7535ec92c0a209db7b 138 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 3 136 5.2E-69 T 28-03-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 A6A12_RS04630 4db9dd3071b47d7535ec92c0a209db7b 138 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 A6A12_RS04630 4db9dd3071b47d7535ec92c0a209db7b 138 SUPERFAMILY SSF54593 3 130 2.55E-36 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A6A12_RS04630 4db9dd3071b47d7535ec92c0a209db7b 138 ProSitePatterns PS00935 Glyoxalase I signature 2. 72 84 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 A6A12_RS06155 ac81ac25471c0217ab67c8e95e551f17 170 PIRSF PIRSF028103 1 170 8.3E-45 T 28-03-2018 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 A6A12_RS06155 ac81ac25471c0217ab67c8e95e551f17 170 SUPERFAMILY SSF55021 88 167 2.54E-12 T 28-03-2018 A6A12_RS06155 ac81ac25471c0217ab67c8e95e551f17 170 Pfam PF13740 ACT domain 4 66 3.0E-9 T 28-03-2018 A6A12_RS06155 ac81ac25471c0217ab67c8e95e551f17 170 Gene3D G3DSA:2.40.30.10 2 97 0.0017 T 28-03-2018 A6A12_RS06155 ac81ac25471c0217ab67c8e95e551f17 170 Gene3D G3DSA:3.30.70.260 98 169 5.1E-12 T 28-03-2018 A6A12_RS05155 828a33e349046b25047aa99577f20272 331 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 33 278 2.5E-79 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 A6A12_RS05155 828a33e349046b25047aa99577f20272 331 PIRSF PIRSF006470 1 331 5.7E-122 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 A6A12_RS05155 828a33e349046b25047aa99577f20272 331 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 33 317 5.1E-103 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 A6A12_RS04410 620c51903177ecc156edb08ec3b21a52 154 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 4 147 24.693 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A6A12_RS04410 620c51903177ecc156edb08ec3b21a52 154 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 39 144 2.5E-38 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A6A12_RS04410 620c51903177ecc156edb08ec3b21a52 154 SUPERFAMILY SSF55486 4 150 1.51E-49 T 28-03-2018 A6A12_RS04410 620c51903177ecc156edb08ec3b21a52 154 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 113 123 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site A6A12_RS04410 620c51903177ecc156edb08ec3b21a52 154 Gene3D G3DSA:3.40.390.30 1 154 1.7E-53 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 A6A12_RS04410 620c51903177ecc156edb08ec3b21a52 154 Pfam PF02130 Uncharacterized protein family UPF0054 23 142 5.4E-39 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 A6A12_RS11895 aec172f3f9a5ddd20251bfccc76f9025 218 Gene3D G3DSA:3.30.70.260 138 196 1.2E-23 T 28-03-2018 A6A12_RS11895 aec172f3f9a5ddd20251bfccc76f9025 218 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 214 3.9E-68 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A6A12_RS11895 aec172f3f9a5ddd20251bfccc76f9025 218 Gene3D G3DSA:3.40.50.1360 1 137 4.6E-40 T 28-03-2018 A6A12_RS11895 aec172f3f9a5ddd20251bfccc76f9025 218 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 217 33.397 T 28-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A6A12_RS11895 aec172f3f9a5ddd20251bfccc76f9025 218 SUPERFAMILY SSF75445 127 198 1.57E-23 T 28-03-2018 A6A12_RS11895 aec172f3f9a5ddd20251bfccc76f9025 218 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 49 213 1.4E-57 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A6A12_RS11895 aec172f3f9a5ddd20251bfccc76f9025 218 SUPERFAMILY SSF100950 1 146 1.16E-47 T 28-03-2018 A6A12_RS04900 cc64e810138fb5feef95cc47491d8357 121 PIRSF PIRSF016789 1 116 1.5E-43 T 28-03-2018 IPR007401 Protein of unknown function DUF454 A6A12_RS04900 cc64e810138fb5feef95cc47491d8357 121 Pfam PF04304 Protein of unknown function (DUF454) 2 110 7.5E-39 T 28-03-2018 IPR007401 Protein of unknown function DUF454 A6A12_RS12170 d165e61bc0f636e79469a7747ca0e9ec 148 SUPERFAMILY SSF55804 1 147 1.57E-40 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A6A12_RS12170 d165e61bc0f636e79469a7747ca0e9ec 148 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 51 67 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain A6A12_RS12170 d165e61bc0f636e79469a7747ca0e9ec 148 TIGRFAM TIGR01419 nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN 2 147 3.9E-53 T 28-03-2018 IPR006320 Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN GO:0008982|GO:0009401 A6A12_RS12170 d165e61bc0f636e79469a7747ca0e9ec 148 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 9 147 2.0E-37 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A6A12_RS12170 d165e61bc0f636e79469a7747ca0e9ec 148 Gene3D G3DSA:3.40.930.10 1 148 1.7E-38 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A6A12_RS11135 a0761a9a7bdee33eec5d4e13e20d034a 403 SUPERFAMILY SSF53383 2 400 4.79E-123 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS11135 a0761a9a7bdee33eec5d4e13e20d034a 403 Gene3D G3DSA:3.90.1150.10 282 399 2.5E-43 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS11135 a0761a9a7bdee33eec5d4e13e20d034a 403 TIGRFAM TIGR03392 FeS_syn_CsdA: cysteine desulfurase, catalytic subunit CsdA 2 403 4.4E-153 T 28-03-2018 IPR022471 Cysteine desulphurase, catalytic subunit, CsdA GO:0016226|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A6A12_RS11135 a0761a9a7bdee33eec5d4e13e20d034a 403 Gene3D G3DSA:3.40.640.10 33 281 5.4E-59 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS11135 a0761a9a7bdee33eec5d4e13e20d034a 403 Pfam PF00266 Aminotransferase class-V 24 392 4.3E-150 T 28-03-2018 IPR000192 Aminotransferase class V domain A6A12_RS11135 a0761a9a7bdee33eec5d4e13e20d034a 403 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 6 401 1.0E-167 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A6A12_RS11135 a0761a9a7bdee33eec5d4e13e20d034a 403 PIRSF PIRSF005572 21 403 1.3E-55 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A6A12_RS02605 c4767942055dc7ce781551b05dcee1da 562 Gene3D G3DSA:3.40.50.300 289 561 9.4E-61 T 28-03-2018 A6A12_RS02605 c4767942055dc7ce781551b05dcee1da 562 SUPERFAMILY SSF160246 1 140 2.88E-32 T 28-03-2018 A6A12_RS02605 c4767942055dc7ce781551b05dcee1da 562 SUPERFAMILY SSF52540 172 559 4.0E-93 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS02605 c4767942055dc7ce781551b05dcee1da 562 Pfam PF00437 Type II/IV secretion system protein 188 455 3.0E-87 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A6A12_RS02605 c4767942055dc7ce781551b05dcee1da 562 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 383 397 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A6A12_RS02605 c4767942055dc7ce781551b05dcee1da 562 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 38 141 1.7E-17 T 28-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 A6A12_RS02605 c4767942055dc7ce781551b05dcee1da 562 Gene3D G3DSA:3.30.450.90 150 288 5.2E-44 T 28-03-2018 A6A12_RS02605 c4767942055dc7ce781551b05dcee1da 562 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 5 559 8.9E-239 T 28-03-2018 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 Gene3D G3DSA:3.30.160.40 222 307 5.9E-24 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 7 298 6.4E-115 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 232 248 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 PRINTS PR00151 Porphobilinogen deaminase signature 46 66 2.1E-47 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 PRINTS PR00151 Porphobilinogen deaminase signature 77 96 2.1E-47 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 PRINTS PR00151 Porphobilinogen deaminase signature 125 142 2.1E-47 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 PRINTS PR00151 Porphobilinogen deaminase signature 144 161 2.1E-47 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 PRINTS PR00151 Porphobilinogen deaminase signature 231 248 2.1E-47 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 Gene3D G3DSA:3.40.190.10 1 107 5.8E-46 T 28-03-2018 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 7 214 9.1E-80 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 SUPERFAMILY SSF53850 6 220 1.52E-85 T 28-03-2018 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 6 298 39.979 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 Gene3D G3DSA:3.40.190.10 108 200 1.5E-38 T 28-03-2018 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 SUPERFAMILY SSF54782 221 310 1.7E-27 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 PIRSF PIRSF001438 1 312 1.2E-122 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A6A12_RS00370 4b62631960eb1db35f0f082f52e712f6 312 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 228 297 4.6E-20 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A6A12_RS13500 51e4b1762c432161eb2423fbf66d3706 269 Gene3D G3DSA:3.20.190.10 1 130 2.8E-35 T 28-03-2018 A6A12_RS13500 51e4b1762c432161eb2423fbf66d3706 269 SUPERFAMILY SSF46946 130 221 1.18E-28 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A6A12_RS13500 51e4b1762c432161eb2423fbf66d3706 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 129 218 9.4E-26 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A6A12_RS13500 51e4b1762c432161eb2423fbf66d3706 269 SUPERFAMILY SSF57716 217 269 1.54E-16 T 28-03-2018 A6A12_RS13500 51e4b1762c432161eb2423fbf66d3706 269 SMART SM01232 129 221 7.5E-42 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 A6A12_RS13500 51e4b1762c432161eb2423fbf66d3706 269 Gene3D G3DSA:1.10.8.50 131 269 3.0E-48 T 28-03-2018 A6A12_RS13500 51e4b1762c432161eb2423fbf66d3706 269 ProSitePatterns PS01242 Zinc finger FPG-type signature. 244 268 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 A6A12_RS13500 51e4b1762c432161eb2423fbf66d3706 269 SMART SM00898 2 115 1.5E-51 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A6A12_RS13500 51e4b1762c432161eb2423fbf66d3706 269 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 268 3.2E-95 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A6A12_RS13500 51e4b1762c432161eb2423fbf66d3706 269 SUPERFAMILY SSF81624 2 138 1.2E-39 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A6A12_RS13500 51e4b1762c432161eb2423fbf66d3706 269 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 269 42.658 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 A6A12_RS13500 51e4b1762c432161eb2423fbf66d3706 269 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 2.0E-30 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 A6A12_RS13500 51e4b1762c432161eb2423fbf66d3706 269 Pfam PF06827 Zinc finger found in FPG and IleRS 242 269 2.4E-8 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 A6A12_RS04060 3b687b62fa43f460c89be69382e0023a 80 PIRSF PIRSF006488 1 78 9.4E-21 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A6A12_RS04060 3b687b62fa43f460c89be69382e0023a 80 Gene3D G3DSA:1.10.287.1040 8 73 2.9E-22 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A6A12_RS04060 3b687b62fa43f460c89be69382e0023a 80 Pfam PF02609 Exonuclease VII small subunit 11 61 2.3E-18 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A6A12_RS04060 3b687b62fa43f460c89be69382e0023a 80 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 10 64 8.0E-21 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A6A12_RS04060 3b687b62fa43f460c89be69382e0023a 80 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 50 7.0E-20 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A6A12_RS04060 3b687b62fa43f460c89be69382e0023a 80 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 10 70 15.287 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 A6A12_RS04060 3b687b62fa43f460c89be69382e0023a 80 SUPERFAMILY SSF116842 2 72 2.35E-20 T 28-03-2018 A6A12_RS10015 eaafe8316c39e7856fab9509fa37040a 237 Pfam PF13534 4Fe-4S dicluster domain 147 220 1.4E-10 T 28-03-2018 A6A12_RS10015 eaafe8316c39e7856fab9509fa37040a 237 Gene3D G3DSA:1.10.1060.10 106 237 6.5E-31 T 28-03-2018 A6A12_RS10015 eaafe8316c39e7856fab9509fa37040a 237 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 148 159 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A6A12_RS10015 eaafe8316c39e7856fab9509fa37040a 237 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 8 229 2.9E-86 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS10015 eaafe8316c39e7856fab9509fa37040a 237 SUPERFAMILY SSF46548 106 234 2.27E-40 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A6A12_RS10015 eaafe8316c39e7856fab9509fa37040a 237 SUPERFAMILY SSF54292 1 105 4.01E-29 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A6A12_RS10015 eaafe8316c39e7856fab9509fa37040a 237 Gene3D G3DSA:3.10.20.30 1 105 5.7E-32 T 28-03-2018 IPR012675 Beta-grasp domain A6A12_RS10015 eaafe8316c39e7856fab9509fa37040a 237 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 5 110 7.8E-29 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS12260 acd6435fe8096e9d9b0a7bdd0e2c8dee 183 Gene3D G3DSA:3.40.30.10 18 182 1.8E-5 T 28-03-2018 A6A12_RS12260 acd6435fe8096e9d9b0a7bdd0e2c8dee 183 TIGRFAM TIGR01626 ytfJ_HI0045: conserved hypothetical protein YtfJ-family, TIGR01626 1 183 3.7E-86 T 28-03-2018 IPR006513 Conserved hypothetical protein CHP01626, YtfJ A6A12_RS12260 acd6435fe8096e9d9b0a7bdd0e2c8dee 183 Pfam PF09695 Bacterial protein of unknown function (YtfJ_HI0045) 23 182 2.5E-75 T 28-03-2018 IPR006513 Conserved hypothetical protein CHP01626, YtfJ A6A12_RS05595 781ac2f4c79a7155141ab63ad04beeda 380 Gene3D G3DSA:3.90.1150.10 278 378 2.7E-36 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS05595 781ac2f4c79a7155141ab63ad04beeda 380 Gene3D G3DSA:3.40.640.10 36 277 1.1E-25 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS05595 781ac2f4c79a7155141ab63ad04beeda 380 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 22 379 51.265 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 A6A12_RS05595 781ac2f4c79a7155141ab63ad04beeda 380 SUPERFAMILY SSF53383 24 377 3.75E-116 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS05595 781ac2f4c79a7155141ab63ad04beeda 380 PIRSF PIRSF000525 18 380 2.5E-152 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 A6A12_RS05595 781ac2f4c79a7155141ab63ad04beeda 380 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 24 379 3.2E-159 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 A6A12_RS05595 781ac2f4c79a7155141ab63ad04beeda 380 Pfam PF00266 Aminotransferase class-V 24 368 5.7E-66 T 28-03-2018 IPR000192 Aminotransferase class V domain A6A12_RS04040 4335dd9d812bc296e7ef8428b612b4e3 106 SUPERFAMILY SSF158452 1 102 2.75E-34 T 28-03-2018 IPR023376 YqcC-like domain A6A12_RS04040 4335dd9d812bc296e7ef8428b612b4e3 106 PIRSF PIRSF006257 1 106 3.7E-37 T 28-03-2018 IPR007384 Protein of unknown function UCP006257 A6A12_RS04040 4335dd9d812bc296e7ef8428b612b4e3 106 Gene3D G3DSA:1.20.1440.40 3 103 3.0E-32 T 28-03-2018 IPR023376 YqcC-like domain A6A12_RS04040 4335dd9d812bc296e7ef8428b612b4e3 106 Pfam PF04287 tRNA pseudouridine synthase C 7 101 8.7E-33 T 28-03-2018 IPR023376 YqcC-like domain A6A12_RS14230 c6c052407482f14d154abddc1849d95d 370 SUPERFAMILY SSF102114 37 332 2.75E-51 T 28-03-2018 A6A12_RS14230 c6c052407482f14d154abddc1849d95d 370 TIGRFAM TIGR02351 thiH: thiazole biosynthesis protein ThiH 3 366 1.1E-169 T 28-03-2018 IPR012726 Thiazole biosynthesis ThiH GO:0005506|GO:0009228|GO:0051539 KEGG: 00730+4.1.99.19|MetaCyc: PWY-6892 A6A12_RS14230 c6c052407482f14d154abddc1849d95d 370 Pfam PF04055 Radical SAM superfamily 81 219 4.0E-9 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A6A12_RS14230 c6c052407482f14d154abddc1849d95d 370 Gene3D G3DSA:3.20.20.70 16 368 2.3E-47 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS14230 c6c052407482f14d154abddc1849d95d 370 SMART SM00876 256 359 1.1E-32 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A6A12_RS14230 c6c052407482f14d154abddc1849d95d 370 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 256 357 4.0E-24 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A6A12_RS01070 6ffba1bc2b7c576e5a9f8b0192fc6105 235 SUPERFAMILY SSF52343 102 233 2.62E-30 T 28-03-2018 A6A12_RS01070 6ffba1bc2b7c576e5a9f8b0192fc6105 235 Pfam PF00970 Oxidoreductase FAD-binding domain 5 97 1.8E-5 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 A6A12_RS01070 6ffba1bc2b7c576e5a9f8b0192fc6105 235 Gene3D G3DSA:2.40.30.10 1 101 1.1E-16 T 28-03-2018 A6A12_RS01070 6ffba1bc2b7c576e5a9f8b0192fc6105 235 Pfam PF00175 Oxidoreductase NAD-binding domain 110 213 6.8E-20 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A6A12_RS01070 6ffba1bc2b7c576e5a9f8b0192fc6105 235 Gene3D G3DSA:3.40.50.80 102 235 1.5E-20 T 28-03-2018 A6A12_RS01070 6ffba1bc2b7c576e5a9f8b0192fc6105 235 SUPERFAMILY SSF63380 2 100 6.45E-19 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A6A12_RS01070 6ffba1bc2b7c576e5a9f8b0192fc6105 235 PRINTS PR00410 Phenol hydroxylase reductase family signature 30 42 1.3E-13 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A6A12_RS01070 6ffba1bc2b7c576e5a9f8b0192fc6105 235 PRINTS PR00410 Phenol hydroxylase reductase family signature 134 143 1.3E-13 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A6A12_RS01070 6ffba1bc2b7c576e5a9f8b0192fc6105 235 PRINTS PR00410 Phenol hydroxylase reductase family signature 94 103 1.3E-13 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A6A12_RS01070 6ffba1bc2b7c576e5a9f8b0192fc6105 235 PRINTS PR00410 Phenol hydroxylase reductase family signature 109 128 1.3E-13 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A6A12_RS01070 6ffba1bc2b7c576e5a9f8b0192fc6105 235 PRINTS PR00410 Phenol hydroxylase reductase family signature 46 53 1.3E-13 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A6A12_RS08860 a9863d923beb9bfe8156d785c0cb249a 244 Gene3D G3DSA:3.60.21.10 1 243 5.9E-26 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A6A12_RS08860 a9863d923beb9bfe8156d785c0cb249a 244 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 3 232 1.1E-108 T 28-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 A6A12_RS08860 a9863d923beb9bfe8156d785c0cb249a 244 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 241 121.884 T 28-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 A6A12_RS08860 a9863d923beb9bfe8156d785c0cb249a 244 Pfam PF00149 Calcineurin-like phosphoesterase 1 199 1.3E-9 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A6A12_RS08860 a9863d923beb9bfe8156d785c0cb249a 244 SUPERFAMILY SSF56300 1 223 1.83E-33 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A6A12_RS02340 fa6e94e8f00b6b7260b60b1bdfca92c5 147 Gene3D G3DSA:1.10.1510.10 1 90 1.8E-28 T 28-03-2018 A6A12_RS02340 fa6e94e8f00b6b7260b60b1bdfca92c5 147 Gene3D G3DSA:1.10.10.410 91 147 1.0E-17 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A6A12_RS02340 fa6e94e8f00b6b7260b60b1bdfca92c5 147 SUPERFAMILY SSF89095 1 146 9.42E-42 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 A6A12_RS02340 fa6e94e8f00b6b7260b60b1bdfca92c5 147 Pfam PF09424 Yqey-like protein 7 146 7.8E-55 T 28-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial A6A12_RS04450 bfae91984537d23ca2bf37baf56d7a63 250 Hamap MF_00468 Sulfate transporter CysZ [cysZ]. 9 249 28.309 T 28-03-2018 IPR022985 Sulfate transporter CysZ GO:0000103|GO:0005887|GO:0015116 A6A12_RS04450 bfae91984537d23ca2bf37baf56d7a63 250 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 15 231 6.1E-39 T 28-03-2018 A6A12_RS05650 d19c96662d73fb8c98375e39384b8415 357 SUPERFAMILY SSF54211 254 344 3.92E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS05650 d19c96662d73fb8c98375e39384b8415 357 Pfam PF08645 Polynucleotide kinase 3 phosphatase 6 133 1.4E-5 T 28-03-2018 IPR013954 Polynucleotide kinase 3 phosphatase Reactome: R-HSA-5649702 A6A12_RS05650 d19c96662d73fb8c98375e39384b8415 357 SUPERFAMILY SSF56784 3 157 7.89E-40 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS05650 d19c96662d73fb8c98375e39384b8415 357 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 321 333 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A6A12_RS05650 d19c96662d73fb8c98375e39384b8415 357 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 169 357 38.179 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A6A12_RS05650 d19c96662d73fb8c98375e39384b8415 357 TIGRFAM TIGR01261 hisB_Nterm: histidinol-phosphatase 5 164 5.3E-79 T 28-03-2018 IPR005954 Histidinol-phosphatase GO:0000105|GO:0004401|GO:0004424|GO:0005737 KEGG: 00340+4.2.1.19+3.1.3.15 A6A12_RS05650 d19c96662d73fb8c98375e39384b8415 357 Gene3D G3DSA:3.30.230.40 169 255 4.3E-35 T 28-03-2018 A6A12_RS05650 d19c96662d73fb8c98375e39384b8415 357 Hamap MF_01022 Histidine biosynthesis bifunctional protein HisB [hisB]. 4 357 51.217 T 28-03-2018 IPR020566 Histidine biosynthesis bifunctional protein HisB GO:0000105|GO:0004401|GO:0004424 KEGG: 00340+4.2.1.19+3.1.3.15 A6A12_RS05650 d19c96662d73fb8c98375e39384b8415 357 SUPERFAMILY SSF54211 169 253 1.26E-32 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS05650 d19c96662d73fb8c98375e39384b8415 357 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 6 147 1.2E-46 T 28-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 A6A12_RS05650 d19c96662d73fb8c98375e39384b8415 357 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 228 241 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A6A12_RS05650 d19c96662d73fb8c98375e39384b8415 357 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 198 339 1.5E-66 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 A6A12_RS05650 d19c96662d73fb8c98375e39384b8415 357 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 6 151 1.2E-27 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A6A12_RS05650 d19c96662d73fb8c98375e39384b8415 357 Gene3D G3DSA:3.30.230.40 257 357 6.7E-32 T 28-03-2018 A6A12_RS05650 d19c96662d73fb8c98375e39384b8415 357 Gene3D G3DSA:3.40.50.1000 2 167 1.2E-24 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS00075 38a0a9514179ebd81e2ee5f7de2b93e9 314 Gene3D G3DSA:3.40.190.10 96 183 5.3E-15 T 28-03-2018 A6A12_RS00075 38a0a9514179ebd81e2ee5f7de2b93e9 314 SUPERFAMILY SSF53850 92 298 4.89E-41 T 28-03-2018 A6A12_RS00075 38a0a9514179ebd81e2ee5f7de2b93e9 314 SUPERFAMILY SSF46785 7 88 4.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS00075 38a0a9514179ebd81e2ee5f7de2b93e9 314 Gene3D G3DSA:1.10.10.10 1 93 4.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS00075 38a0a9514179ebd81e2ee5f7de2b93e9 314 Gene3D G3DSA:3.40.190.10 184 271 2.4E-13 T 28-03-2018 A6A12_RS00075 38a0a9514179ebd81e2ee5f7de2b93e9 314 Pfam PF03466 LysR substrate binding domain 98 299 2.6E-23 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS00075 38a0a9514179ebd81e2ee5f7de2b93e9 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 2.6E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS00075 38a0a9514179ebd81e2ee5f7de2b93e9 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 3.5E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS00075 38a0a9514179ebd81e2ee5f7de2b93e9 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 3.5E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS00075 38a0a9514179ebd81e2ee5f7de2b93e9 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 3.5E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS06965 45174d8b9d7b4bff327a32a4302ae1ad 376 Gene3D G3DSA:2.60.120.10 16 160 2.5E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS06965 45174d8b9d7b4bff327a32a4302ae1ad 376 Gene3D G3DSA:2.60.120.10 161 352 4.0E-43 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS06965 45174d8b9d7b4bff327a32a4302ae1ad 376 SUPERFAMILY SSF51182 63 374 4.45E-91 T 28-03-2018 IPR011051 RmlC-like cupin domain A6A12_RS06965 45174d8b9d7b4bff327a32a4302ae1ad 376 Pfam PF04209 homogentisate 1,2-dioxygenase 90 374 1.6E-23 T 28-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 A6A12_RS05300 0db48c8fc87ebcd9a2fedd0db4096988 426 Pfam PF01593 Flavin containing amine oxidoreductase 12 304 2.2E-23 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 A6A12_RS05300 0db48c8fc87ebcd9a2fedd0db4096988 426 Gene3D G3DSA:3.90.660.20 40 424 2.8E-34 T 28-03-2018 A6A12_RS05300 0db48c8fc87ebcd9a2fedd0db4096988 426 Gene3D G3DSA:3.40.50.720 2 39 8.8E-6 T 28-03-2018 A6A12_RS05300 0db48c8fc87ebcd9a2fedd0db4096988 426 SUPERFAMILY SSF51905 384 414 5.76E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS05300 0db48c8fc87ebcd9a2fedd0db4096988 426 SUPERFAMILY SSF51905 3 301 5.76E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 Hamap MF_00456 Glutamate 5-kinase [proB]. 14 268 35.929 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 Gene3D G3DSA:3.40.1160.10 2 274 8.3E-59 T 28-03-2018 A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 Pfam PF00696 Amino acid kinase family 15 243 2.0E-43 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 SMART SM00359 286 369 9.9E-17 T 28-03-2018 IPR002478 PUA domain GO:0003723 A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 PRINTS PR00474 Glutamate 5-kinase family signature 51 65 1.5E-54 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 PRINTS PR00474 Glutamate 5-kinase family signature 85 113 1.5E-54 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 PRINTS PR00474 Glutamate 5-kinase family signature 218 238 1.5E-54 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 PRINTS PR00474 Glutamate 5-kinase family signature 157 184 1.5E-54 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 PRINTS PR00474 Glutamate 5-kinase family signature 125 146 1.5E-54 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 Pfam PF01472 PUA domain 286 357 6.3E-21 T 28-03-2018 IPR002478 PUA domain GO:0003723 A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 SUPERFAMILY SSF88697 286 376 1.93E-24 T 28-03-2018 IPR015947 PUA-like domain A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 PIRSF PIRSF000729 9 378 6.3E-137 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 ProSitePatterns PS00902 Glutamate 5-kinase signature. 216 233 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 Gene3D G3DSA:2.30.130.10 284 376 1.1E-28 T 28-03-2018 IPR002478 PUA domain GO:0003723 A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 TIGRFAM TIGR01027 proB: glutamate 5-kinase 14 375 3.3E-148 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A6A12_RS10975 1d5bd0312faf74adade18c99019b48ee 379 SUPERFAMILY SSF53633 14 265 1.07E-65 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS07590 23d18f5cc62a7f41cd8afdb341af0770 559 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 452 538 2.6E-14 T 28-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal A6A12_RS07590 23d18f5cc62a7f41cd8afdb341af0770 559 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 112 412 3.7E-93 T 28-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal A6A12_RS07590 23d18f5cc62a7f41cd8afdb341af0770 559 SMART SM00640 112 516 4.0E-125 T 28-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 A6A12_RS07590 23d18f5cc62a7f41cd8afdb341af0770 559 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 112 125 - T 28-03-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 A6A12_RS07590 23d18f5cc62a7f41cd8afdb341af0770 559 SUPERFAMILY SSF49899 413 539 2.06E-18 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain A6A12_RS07590 23d18f5cc62a7f41cd8afdb341af0770 559 Gene3D G3DSA:2.115.10.20 117 436 2.3E-87 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain A6A12_RS07590 23d18f5cc62a7f41cd8afdb341af0770 559 Gene3D G3DSA:2.60.120.560 437 548 2.9E-16 T 28-03-2018 A6A12_RS07590 23d18f5cc62a7f41cd8afdb341af0770 559 SUPERFAMILY SSF75005 105 413 2.98E-95 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain A6A12_RS07590 23d18f5cc62a7f41cd8afdb341af0770 559 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 106 526 8.6E-138 T 28-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 A6A12_RS05060 9830115e42764a9e40f8d0e7b1f5907d 315 Gene3D G3DSA:3.40.190.10 88 178 2.4E-17 T 28-03-2018 A6A12_RS05060 9830115e42764a9e40f8d0e7b1f5907d 315 Gene3D G3DSA:3.40.190.10 179 266 2.1E-26 T 28-03-2018 A6A12_RS05060 9830115e42764a9e40f8d0e7b1f5907d 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 3.0E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS05060 9830115e42764a9e40f8d0e7b1f5907d 315 SUPERFAMILY SSF46785 7 90 1.45E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05060 9830115e42764a9e40f8d0e7b1f5907d 315 Gene3D G3DSA:1.10.10.10 5 86 1.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05060 9830115e42764a9e40f8d0e7b1f5907d 315 SUPERFAMILY SSF53850 90 299 5.61E-47 T 28-03-2018 A6A12_RS05060 9830115e42764a9e40f8d0e7b1f5907d 315 Pfam PF03466 LysR substrate binding domain 90 294 1.6E-44 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS06375 d006e0f5778db1f28286765c1a499144 233 Pfam PF00072 Response regulator receiver domain 8 115 5.6E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS06375 d006e0f5778db1f28286765c1a499144 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 7.8E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS06375 d006e0f5778db1f28286765c1a499144 233 SMART SM00448 5 115 1.3E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS06375 d006e0f5778db1f28286765c1a499144 233 Gene3D G3DSA:1.10.10.10 132 233 1.9E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS06375 d006e0f5778db1f28286765c1a499144 233 SMART SM00862 152 228 7.6E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS06375 d006e0f5778db1f28286765c1a499144 233 SUPERFAMILY SSF46894 128 230 6.52E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS06375 d006e0f5778db1f28286765c1a499144 233 Gene3D G3DSA:3.40.50.2300 1 131 3.0E-30 T 28-03-2018 A6A12_RS06375 d006e0f5778db1f28286765c1a499144 233 SUPERFAMILY SSF52172 3 123 9.39E-34 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS10220 61f328dea09c2c09fb4375cc11197d0e 580 Pfam PF01514 Secretory protein of YscJ/FliF family 63 249 3.0E-56 T 28-03-2018 IPR006182 Secretory protein YscJ/FliF A6A12_RS10220 61f328dea09c2c09fb4375cc11197d0e 580 PRINTS PR01009 Flagellar M-ring protein signature 150 168 9.4E-23 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A6A12_RS10220 61f328dea09c2c09fb4375cc11197d0e 580 PRINTS PR01009 Flagellar M-ring protein signature 225 243 9.4E-23 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A6A12_RS10220 61f328dea09c2c09fb4375cc11197d0e 580 PRINTS PR01009 Flagellar M-ring protein signature 295 313 9.4E-23 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A6A12_RS10220 61f328dea09c2c09fb4375cc11197d0e 580 PRINTS PR01009 Flagellar M-ring protein signature 182 196 9.4E-23 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A6A12_RS10220 61f328dea09c2c09fb4375cc11197d0e 580 PRINTS PR01009 Flagellar M-ring protein signature 375 399 9.4E-23 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A6A12_RS10220 61f328dea09c2c09fb4375cc11197d0e 580 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 53 494 3.1E-73 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A6A12_RS10220 61f328dea09c2c09fb4375cc11197d0e 580 PIRSF PIRSF004862 28 580 1.9E-158 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 A6A12_RS10220 61f328dea09c2c09fb4375cc11197d0e 580 Pfam PF08345 Flagellar M-ring protein C-terminal 282 452 9.9E-39 T 28-03-2018 IPR013556 Flagellar M-ring C-terminal A6A12_RS07030 e8408f969a211e10c8cf8b1e954b7991 841 SUPERFAMILY SSF52540 148 296 3.49E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS07030 e8408f969a211e10c8cf8b1e954b7991 841 SUPERFAMILY SSF52540 432 519 3.49E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS07030 e8408f969a211e10c8cf8b1e954b7991 841 SUPERFAMILY SSF52540 346 400 3.49E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS07030 e8408f969a211e10c8cf8b1e954b7991 841 Pfam PF00270 DEAD/DEAH box helicase 137 286 4.7E-15 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A6A12_RS07030 e8408f969a211e10c8cf8b1e954b7991 841 SMART SM00490 426 508 1.8E-10 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS07030 e8408f969a211e10c8cf8b1e954b7991 841 SMART SM00487 132 318 3.1E-13 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS07030 e8408f969a211e10c8cf8b1e954b7991 841 Gene3D G3DSA:3.40.50.300 355 577 1.0E-15 T 28-03-2018 A6A12_RS07030 e8408f969a211e10c8cf8b1e954b7991 841 Pfam PF00271 Helicase conserved C-terminal domain 406 506 1.1E-6 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS07030 e8408f969a211e10c8cf8b1e954b7991 841 Gene3D G3DSA:3.40.50.300 138 315 3.2E-17 T 28-03-2018 A6A12_RS01895 e8ab74c59c6c76a21b91ac159591aac9 385 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 7 374 6.2E-139 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 A6A12_RS01895 e8ab74c59c6c76a21b91ac159591aac9 385 SMART SM00729 6 227 2.4E-50 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A6A12_RS01895 e8ab74c59c6c76a21b91ac159591aac9 385 Pfam PF06969 HemN C-terminal domain 310 370 1.2E-8 T 28-03-2018 IPR010723 HemN, C-terminal A6A12_RS01895 e8ab74c59c6c76a21b91ac159591aac9 385 Pfam PF04055 Radical SAM superfamily 11 179 6.6E-17 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A6A12_RS01895 e8ab74c59c6c76a21b91ac159591aac9 385 SUPERFAMILY SSF102114 5 382 2.62E-106 T 28-03-2018 A6A12_RS01895 e8ab74c59c6c76a21b91ac159591aac9 385 Gene3D G3DSA:3.20.20.70 3 298 8.3E-44 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS05440 60b974b4b5b9dae6949d824d6c2d0090 206 SUPERFAMILY SSF55821 1 203 4.27E-65 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain A6A12_RS05440 60b974b4b5b9dae6949d824d6c2d0090 206 Pfam PF01300 Telomere recombination 23 198 2.6E-46 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 A6A12_RS05440 60b974b4b5b9dae6949d824d6c2d0090 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 1.6E-70 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 A6A12_RS05440 60b974b4b5b9dae6949d824d6c2d0090 206 Gene3D G3DSA:3.90.870.10 1 204 1.2E-60 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain A6A12_RS08010 25e038da969893049cf7b7d7c339b833 357 Hamap MF_01004 Vitamin B12 import system permease protein BtuC [btuC]. 29 355 29.889 T 28-03-2018 IPR023691 ABC transporter, vitamin B12 import, permease protein BtuC GO:0015889|GO:0016020 A6A12_RS08010 25e038da969893049cf7b7d7c339b833 357 SUPERFAMILY SSF81345 32 352 4.18E-82 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A6A12_RS08010 25e038da969893049cf7b7d7c339b833 357 Gene3D G3DSA:1.10.3470.10 35 357 2.6E-59 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A6A12_RS08010 25e038da969893049cf7b7d7c339b833 357 Pfam PF01032 FecCD transport family 50 352 1.8E-83 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A6A12_RS01305 d9f79af58353e11ac2850d9059cc2841 429 Pfam PF16360 GTP-binding GTPase Middle Region 114 192 1.9E-28 T 28-03-2018 IPR032305 GTP-binding protein, middle domain A6A12_RS01305 d9f79af58353e11ac2850d9059cc2841 429 Gene3D G3DSA:3.40.50.300 157 424 1.8E-30 T 28-03-2018 A6A12_RS01305 d9f79af58353e11ac2850d9059cc2841 429 Pfam PF01926 50S ribosome-binding GTPase 200 318 4.6E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS01305 d9f79af58353e11ac2850d9059cc2841 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 267 285 4.6E-10 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS01305 d9f79af58353e11ac2850d9059cc2841 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 4.6E-10 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS01305 d9f79af58353e11ac2850d9059cc2841 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 221 239 4.6E-10 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS01305 d9f79af58353e11ac2850d9059cc2841 429 SUPERFAMILY SSF54980 366 428 6.47E-15 T 28-03-2018 IPR035647 EF-G domain III/V-like A6A12_RS01305 d9f79af58353e11ac2850d9059cc2841 429 SUPERFAMILY SSF52540 197 375 6.64E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01305 d9f79af58353e11ac2850d9059cc2841 429 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 361 2.8E-156 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 A6A12_RS01305 d9f79af58353e11ac2850d9059cc2841 429 PIRSF PIRSF006809 3 423 5.2E-150 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 A6A12_RS01305 d9f79af58353e11ac2850d9059cc2841 429 Hamap MF_00900 GTPase HflX [hflX]. 27 390 45.693 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 A6A12_RS01305 d9f79af58353e11ac2850d9059cc2841 429 Pfam PF13167 GTP-binding GTPase N-terminal 26 112 4.9E-31 T 28-03-2018 IPR025121 GTPase HflX, N-terminal A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 SUPERFAMILY SSF81665 362 456 3.01E-18 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 SUPERFAMILY SSF81665 214 265 3.01E-18 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 SUPERFAMILY SSF81665 706 745 3.01E-18 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 Gene3D G3DSA:3.40.50.1000 583 729 4.0E-37 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 234 736 5.1E-83 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 Pfam PF00702 haloacid dehalogenase-like hydrolase 459 670 1.3E-38 T 28-03-2018 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 Gene3D G3DSA:3.30.70.100 68 138 1.3E-15 T 28-03-2018 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 SUPERFAMILY SSF55008 71 139 2.88E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 Gene3D G3DSA:1.20.1110.10 214 478 1.7E-34 T 28-03-2018 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 211 514 5.6E-96 T 28-03-2018 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 Pfam PF00122 E1-E2 ATPase 262 442 5.8E-51 T 28-03-2018 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 462 476 3.6E-28 T 28-03-2018 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 657 676 3.6E-28 T 28-03-2018 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 680 692 3.6E-28 T 28-03-2018 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 584 595 3.6E-28 T 28-03-2018 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 311 325 3.6E-28 T 28-03-2018 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 606 616 3.6E-28 T 28-03-2018 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 PRINTS PR00941 Cadmium-transporting ATPase signature 246 266 1.4E-6 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 PRINTS PR00941 Cadmium-transporting ATPase signature 72 81 1.4E-6 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 PRINTS PR00941 Cadmium-transporting ATPase signature 83 104 1.4E-6 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 PRINTS PR00941 Cadmium-transporting ATPase signature 346 360 1.4E-6 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 ProSitePatterns PS01047 Heavy-metal-associated domain. 74 103 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 211 759 7.5E-178 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 ProSitePatterns PS01229 Hypothetical cof family signature 2. 657 679 - T 28-03-2018 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 230 759 1.2E-119 T 28-03-2018 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 464 470 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 Gene3D G3DSA:3.40.1110.10 479 582 3.5E-27 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 SUPERFAMILY SSF81653 264 361 2.48E-22 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 Pfam PF00403 Heavy-metal-associated domain 74 130 5.9E-12 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 SUPERFAMILY SSF56784 556 757 2.42E-51 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS04800 a5719f918a33579dd344169889155ec1 764 SUPERFAMILY SSF56784 461 480 2.42E-51 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 Gene3D G3DSA:3.90.650.10 427 609 5.8E-29 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 Gene3D G3DSA:3.90.650.10 823 997 8.0E-31 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 SUPERFAMILY SSF56042 826 1036 2.39E-52 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 SUPERFAMILY SSF56042 433 616 6.88E-53 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 SUPERFAMILY SSF52317 1038 1296 1.89E-98 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 Pfam PF02769 AIR synthase related protein, C-terminal domain 433 590 2.9E-27 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 Pfam PF02769 AIR synthase related protein, C-terminal domain 835 970 6.2E-14 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1042 1295 2.9E-105 T 28-03-2018 A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1298 21.228 T 28-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 SUPERFAMILY SSF82697 1 150 4.6E-50 T 28-03-2018 A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 Gene3D G3DSA:3.30.1330.10 187 218 0.0034 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 Gene3D G3DSA:3.30.1330.10 219 426 6.1E-48 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 Gene3D G3DSA:3.30.1330.10 613 814 1.9E-23 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 3 1296 0.0 T 28-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 SUPERFAMILY SSF109736 155 221 2.22E-20 T 28-03-2018 A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 SUPERFAMILY SSF55326 619 817 9.68E-70 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 SUPERFAMILY SSF55326 222 429 2.37E-64 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 SMART SM01211 1042 1297 2.0E-156 T 28-03-2018 A6A12_RS03970 f6eb0ea7d846cfb6c23393e9cb2ccc78 1298 Gene3D G3DSA:3.40.50.880 1041 1297 1.7E-32 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS02180 0a28eec1d9584a0c0b21d4cbae597789 400 Pfam PF00589 Phage integrase family 215 381 1.2E-24 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS02180 0a28eec1d9584a0c0b21d4cbae597789 400 Pfam PF13356 Arm DNA-binding domain 15 104 3.0E-11 T 28-03-2018 IPR025166 Integrase, DNA-binding domain A6A12_RS02180 0a28eec1d9584a0c0b21d4cbae597789 400 Gene3D G3DSA:1.10.443.10 226 390 9.5E-37 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS02180 0a28eec1d9584a0c0b21d4cbae597789 400 SUPERFAMILY SSF56349 112 387 2.94E-60 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS02180 0a28eec1d9584a0c0b21d4cbae597789 400 Gene3D G3DSA:1.10.150.130 101 225 3.1E-20 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A6A12_RS01395 6b848ce492164be5567eee969474e13a 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 66 148 2.8E-23 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal A6A12_RS01395 6b848ce492164be5567eee969474e13a 149 SUPERFAMILY SSF55658 1 57 4.01E-19 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal A6A12_RS01395 6b848ce492164be5567eee969474e13a 149 SUPERFAMILY SSF55653 60 149 9.81E-24 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal A6A12_RS01395 6b848ce492164be5567eee969474e13a 149 Gene3D G3DSA:3.40.5.10 1 49 4.3E-22 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01395 6b848ce492164be5567eee969474e13a 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 1.5E-21 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01395 6b848ce492164be5567eee969474e13a 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01395 6b848ce492164be5567eee969474e13a 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 149 2.2E-53 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS01395 6b848ce492164be5567eee969474e13a 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 149 25.584 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS01395 6b848ce492164be5567eee969474e13a 149 Gene3D G3DSA:3.10.430.100 63 148 2.0E-24 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 532 25.817 T 28-03-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 350 529 5.3E-73 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 PRINTS PR01900 YidC translocation/secretion protein signature 336 352 3.2E-26 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 PRINTS PR01900 YidC translocation/secretion protein signature 465 480 3.2E-26 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 PRINTS PR01900 YidC translocation/secretion protein signature 485 509 3.2E-26 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 Pfam PF02096 60Kd inner membrane protein 351 530 2.2E-63 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 PRINTS PR00701 60kDa inner membrane protein signature 459 481 2.4E-99 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 PRINTS PR00701 60kDa inner membrane protein signature 496 519 2.4E-99 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 PRINTS PR00701 60kDa inner membrane protein signature 71 92 2.4E-99 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 PRINTS PR00701 60kDa inner membrane protein signature 321 341 2.4E-99 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 PRINTS PR00701 60kDa inner membrane protein signature 2 23 2.4E-99 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 PRINTS PR00701 60kDa inner membrane protein signature 249 264 2.4E-99 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 PRINTS PR00701 60kDa inner membrane protein signature 214 232 2.4E-99 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 PRINTS PR00701 60kDa inner membrane protein signature 161 181 2.4E-99 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 PRINTS PR00701 60kDa inner membrane protein signature 412 435 2.4E-99 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 Pfam PF14849 YidC periplasmic domain 65 339 3.7E-82 T 28-03-2018 IPR028053 Membrane insertase YidC, N-terminal A6A12_RS14420 93fd5b5cc22773116a027239628cac95 540 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 3 348 2.6E-110 T 28-03-2018 IPR028053 Membrane insertase YidC, N-terminal A6A12_RS10105 afe20223df603ad4057cb6034424d6e1 381 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 257 7.3E-33 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A6A12_RS10105 afe20223df603ad4057cb6034424d6e1 381 Pfam PF11890 Domain of unknown function (DUF3410) 290 370 6.7E-28 T 28-03-2018 IPR024531 Erythronate-4-phosphate dehydrogenase, dimerisation domain GO:0046983 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181 A6A12_RS10105 afe20223df603ad4057cb6034424d6e1 381 Hamap MF_01825 Erythronate-4-phosphate dehydrogenase [pdxB]. 1 358 45.577 T 28-03-2018 IPR020921 Erythronate-4-phosphate dehydrogenase GO:0005737|GO:0008615|GO:0033711|GO:0055114 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181 A6A12_RS10105 afe20223df603ad4057cb6034424d6e1 381 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 198 214 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A6A12_RS10105 afe20223df603ad4057cb6034424d6e1 381 SUPERFAMILY SSF52283 4 102 4.46E-22 T 28-03-2018 A6A12_RS10105 afe20223df603ad4057cb6034424d6e1 381 Gene3D G3DSA:3.40.50.720 106 258 6.6E-31 T 28-03-2018 A6A12_RS10105 afe20223df603ad4057cb6034424d6e1 381 SUPERFAMILY SSF51735 93 257 1.29E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS10105 afe20223df603ad4057cb6034424d6e1 381 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 287 2.5E-22 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A6A12_RS10105 afe20223df603ad4057cb6034424d6e1 381 Gene3D G3DSA:3.40.50.720 1 105 1.0E-25 T 28-03-2018 A6A12_RS10100 8f590e2f738af744508bb21f4cb13c47 337 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 232 246 - T 28-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS10100 8f590e2f738af744508bb21f4cb13c47 337 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 319 4.5E-62 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 A6A12_RS10100 8f590e2f738af744508bb21f4cb13c47 337 SMART SM00859 6 121 1.7E-39 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A6A12_RS10100 8f590e2f738af744508bb21f4cb13c47 337 PIRSF PIRSF000148 4 337 4.3E-133 T 28-03-2018 A6A12_RS10100 8f590e2f738af744508bb21f4cb13c47 337 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 120 2.8E-31 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 A6A12_RS10100 8f590e2f738af744508bb21f4cb13c47 337 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 6 334 6.0E-132 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS10100 8f590e2f738af744508bb21f4cb13c47 337 SUPERFAMILY SSF55347 131 320 4.17E-78 T 28-03-2018 A6A12_RS10100 8f590e2f738af744508bb21f4cb13c47 337 Gene3D G3DSA:3.30.360.10 144 315 3.9E-73 T 28-03-2018 A6A12_RS10100 8f590e2f738af744508bb21f4cb13c47 337 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 4 333 36.487 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS10100 8f590e2f738af744508bb21f4cb13c47 337 Gene3D G3DSA:3.40.50.720 1 143 1.7E-32 T 28-03-2018 A6A12_RS10100 8f590e2f738af744508bb21f4cb13c47 337 SUPERFAMILY SSF51735 5 159 1.48E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS06880 e9c4b7f8f0df970dd0b724579cf032bd 288 PIRSF PIRSF006221 1 288 6.1E-104 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 A6A12_RS06880 e9c4b7f8f0df970dd0b724579cf032bd 288 Pfam PF03881 Fructosamine kinase 1 287 1.3E-120 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 A6A12_RS06880 e9c4b7f8f0df970dd0b724579cf032bd 288 SUPERFAMILY SSF56112 5 282 3.06E-41 T 28-03-2018 IPR011009 Protein kinase-like domain A6A12_RS06880 e9c4b7f8f0df970dd0b724579cf032bd 288 Gene3D G3DSA:3.90.1200.10 86 285 7.4E-14 T 28-03-2018 A6A12_RS06880 e9c4b7f8f0df970dd0b724579cf032bd 288 Gene3D G3DSA:3.30.200.20 1 85 9.2E-18 T 28-03-2018 A6A12_RS04075 bc19175b9d6dbecc36da99b8782c4aa1 482 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 369 1.5E-70 T 28-03-2018 IPR020536 Thil, AANH domain GO:0004810 A6A12_RS04075 bc19175b9d6dbecc36da99b8782c4aa1 482 Gene3D G3DSA:3.40.50.620 175 402 4.4E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS04075 bc19175b9d6dbecc36da99b8782c4aa1 482 SMART SM00981 75 165 2.8E-24 T 28-03-2018 IPR004114 THUMP domain GO:0003723 A6A12_RS04075 bc19175b9d6dbecc36da99b8782c4aa1 482 Gene3D G3DSA:3.40.250.10 403 481 3.4E-12 T 28-03-2018 IPR001763 Rhodanese-like domain A6A12_RS04075 bc19175b9d6dbecc36da99b8782c4aa1 482 SUPERFAMILY SSF52821 403 481 6.02E-12 T 28-03-2018 IPR001763 Rhodanese-like domain A6A12_RS04075 bc19175b9d6dbecc36da99b8782c4aa1 482 SUPERFAMILY SSF143437 1 173 2.96E-48 T 28-03-2018 A6A12_RS04075 bc19175b9d6dbecc36da99b8782c4aa1 482 SUPERFAMILY SSF52402 174 372 2.43E-41 T 28-03-2018 A6A12_RS04075 bc19175b9d6dbecc36da99b8782c4aa1 482 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 4 373 5.6E-114 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 A6A12_RS04075 bc19175b9d6dbecc36da99b8782c4aa1 482 Gene3D G3DSA:3.30.2300.10 83 160 5.9E-23 T 28-03-2018 A6A12_RS04075 bc19175b9d6dbecc36da99b8782c4aa1 482 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 482 222.315 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 A6A12_RS04075 bc19175b9d6dbecc36da99b8782c4aa1 482 TIGRFAM TIGR04271 ThiI_C_thiazole: thiazole biosynthesis domain 382 482 7.6E-42 T 28-03-2018 IPR026340 Thiazole biosynthesis domain GO:0052837 A6A12_RS04075 bc19175b9d6dbecc36da99b8782c4aa1 482 Pfam PF02926 THUMP domain 60 156 9.7E-23 T 28-03-2018 IPR004114 THUMP domain GO:0003723 A6A12_RS04075 bc19175b9d6dbecc36da99b8782c4aa1 482 Gene3D G3DSA:3.30.70.1510 2 82 7.8E-20 T 28-03-2018 A6A12_RS09735 d18a8579b882e8f78ef74da427f08504 890 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 631 659 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A6A12_RS09735 d18a8579b882e8f78ef74da427f08504 890 Pfam PF00171 Aldehyde dehydrogenase family 5 402 2.4E-24 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A6A12_RS09735 d18a8579b882e8f78ef74da427f08504 890 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 719 739 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 A6A12_RS09735 d18a8579b882e8f78ef74da427f08504 890 Gene3D G3DSA:3.40.309.10 228 405 8.2E-25 T 28-03-2018 A6A12_RS09735 d18a8579b882e8f78ef74da427f08504 890 Gene3D G3DSA:3.40.605.10 1 227 6.8E-30 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A6A12_RS09735 d18a8579b882e8f78ef74da427f08504 890 SUPERFAMILY SSF56796 452 863 2.62E-115 T 28-03-2018 A6A12_RS09735 d18a8579b882e8f78ef74da427f08504 890 Gene3D G3DSA:1.20.1090.10 643 867 8.5E-59 T 28-03-2018 A6A12_RS09735 d18a8579b882e8f78ef74da427f08504 890 Pfam PF00465 Iron-containing alcohol dehydrogenase 458 849 1.3E-112 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A6A12_RS09735 d18a8579b882e8f78ef74da427f08504 890 Gene3D G3DSA:3.40.50.1970 431 642 1.4E-49 T 28-03-2018 A6A12_RS09735 d18a8579b882e8f78ef74da427f08504 890 PIRSF PIRSF000111 1 865 0.0 T 28-03-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 A6A12_RS09735 d18a8579b882e8f78ef74da427f08504 890 SUPERFAMILY SSF53720 6 454 5.63E-83 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 Gene3D G3DSA:3.20.20.80 247 637 6.2E-134 T 28-03-2018 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 SUPERFAMILY SSF55545 126 257 3.66E-26 T 28-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 258 605 2.3E-119 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 138 255 3.4E-18 T 28-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 PIRSF PIRSF001093 189 636 5.0E-89 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 PIRSF PIRSF001093 111 189 68.0 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 Gene3D G3DSA:3.30.379.10 130 246 1.2E-20 T 28-03-2018 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 PRINTS PR00738 Glycosyl hydrolase family 20 signature 400 418 4.0E-50 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 PRINTS PR00738 Glycosyl hydrolase family 20 signature 422 435 4.0E-50 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 PRINTS PR00738 Glycosyl hydrolase family 20 signature 217 237 4.0E-50 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 PRINTS PR00738 Glycosyl hydrolase family 20 signature 569 585 4.0E-50 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 PRINTS PR00738 Glycosyl hydrolase family 20 signature 351 368 4.0E-50 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 PRINTS PR00738 Glycosyl hydrolase family 20 signature 587 604 4.0E-50 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 PRINTS PR00738 Glycosyl hydrolase family 20 signature 281 302 4.0E-50 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 PRINTS PR00738 Glycosyl hydrolase family 20 signature 252 269 4.0E-50 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 A6A12_RS02810 8b88bb429b6aaf19a6cfc6730ba33422 637 SUPERFAMILY SSF51445 258 618 6.59E-127 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A6A12_RS00050 38af743b0c99a49a0ff5b95a068525e0 305 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 9 292 4.6E-150 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00050 38af743b0c99a49a0ff5b95a068525e0 305 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 7 301 3.6E-174 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00050 38af743b0c99a49a0ff5b95a068525e0 305 Gene3D G3DSA:3.30.930.10 1 214 3.6E-87 T 28-03-2018 A6A12_RS00050 38af743b0c99a49a0ff5b95a068525e0 305 SUPERFAMILY SSF55681 8 292 4.57E-135 T 28-03-2018 A6A12_RS00050 38af743b0c99a49a0ff5b95a068525e0 305 Gene3D G3DSA:1.20.58.180 216 294 2.6E-33 T 28-03-2018 A6A12_RS00050 38af743b0c99a49a0ff5b95a068525e0 305 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 7 293 62.037 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00050 38af743b0c99a49a0ff5b95a068525e0 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 162 177 4.2E-71 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00050 38af743b0c99a49a0ff5b95a068525e0 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 139 159 4.2E-71 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00050 38af743b0c99a49a0ff5b95a068525e0 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 113 137 4.2E-71 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00050 38af743b0c99a49a0ff5b95a068525e0 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 82 102 4.2E-71 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00050 38af743b0c99a49a0ff5b95a068525e0 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 253 269 4.2E-71 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00050 38af743b0c99a49a0ff5b95a068525e0 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 61 76 4.2E-71 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS12660 a8072f23b0be377bae598bdd05792090 224 Gene3D G3DSA:3.20.20.70 1 220 2.5E-87 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS12660 a8072f23b0be377bae598bdd05792090 224 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 216 9.8E-99 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A6A12_RS12660 a8072f23b0be377bae598bdd05792090 224 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 136 158 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A6A12_RS12660 a8072f23b0be377bae598bdd05792090 224 PIRSF PIRSF001461 1 224 8.0E-105 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A6A12_RS12660 a8072f23b0be377bae598bdd05792090 224 SUPERFAMILY SSF51366 4 218 6.53E-76 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A6A12_RS12660 a8072f23b0be377bae598bdd05792090 224 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 203 1.4E-90 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A6A12_RS12660 a8072f23b0be377bae598bdd05792090 224 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 A6A12_RS02470 41ac5dd856c50a45ea861415b9446d50 395 PIRSF PIRSF000726 307 385 4.4 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS02470 41ac5dd856c50a45ea861415b9446d50 395 PIRSF PIRSF000726 3 63 5.0E-23 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS02470 41ac5dd856c50a45ea861415b9446d50 395 PIRSF PIRSF000726 59 298 5.7E-74 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS02470 41ac5dd856c50a45ea861415b9446d50 395 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 65 379 1.5E-75 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS02470 41ac5dd856c50a45ea861415b9446d50 395 Gene3D G3DSA:3.30.70.260 246 382 1.0E-13 T 28-03-2018 A6A12_RS02470 41ac5dd856c50a45ea861415b9446d50 395 SUPERFAMILY SSF53633 6 243 2.36E-74 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS02470 41ac5dd856c50a45ea861415b9446d50 395 Gene3D G3DSA:3.40.1160.10 4 245 1.0E-73 T 28-03-2018 A6A12_RS02470 41ac5dd856c50a45ea861415b9446d50 395 ProSitePatterns PS00324 Aspartokinase signature. 7 15 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS02470 41ac5dd856c50a45ea861415b9446d50 395 Pfam PF00696 Amino acid kinase family 5 231 1.4E-52 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS04780 919e0f739f6c4f5a3fe646ad09bbe0b2 81 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 81 4.3E-24 T 28-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 A6A12_RS04780 919e0f739f6c4f5a3fe646ad09bbe0b2 81 SUPERFAMILY SSF54285 1 81 2.94E-23 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A6A12_RS04780 919e0f739f6c4f5a3fe646ad09bbe0b2 81 Pfam PF02597 ThiS family 4 81 7.7E-23 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 A6A12_RS04780 919e0f739f6c4f5a3fe646ad09bbe0b2 81 Gene3D G3DSA:3.10.20.30 1 81 1.7E-19 T 28-03-2018 IPR012675 Beta-grasp domain A6A12_RS04780 919e0f739f6c4f5a3fe646ad09bbe0b2 81 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 2 81 6.1E-14 T 28-03-2018 IPR010038 MoaD, archaeal-type A6A12_RS06900 2a8c0bfb440b730fa0f39283bbd883c3 287 Gene3D G3DSA:3.40.1090.10 6 228 7.0E-25 T 28-03-2018 A6A12_RS06900 2a8c0bfb440b730fa0f39283bbd883c3 287 Pfam PF01734 Patatin-like phospholipase 12 176 7.3E-13 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 A6A12_RS06900 2a8c0bfb440b730fa0f39283bbd883c3 287 SUPERFAMILY SSF52151 10 240 8.63E-35 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A6A12_RS01220 9d9f570cde7d8ace23d0bbf70314b85e 383 Gene3D G3DSA:1.20.5.320 34 139 4.7E-8 T 28-03-2018 A6A12_RS01220 9d9f570cde7d8ace23d0bbf70314b85e 383 Gene3D G3DSA:1.20.5.340 143 249 0.23 T 28-03-2018 A6A12_RS01220 9d9f570cde7d8ace23d0bbf70314b85e 383 Gene3D G3DSA:2.70.70.10 250 383 2.8E-31 T 28-03-2018 A6A12_RS01220 9d9f570cde7d8ace23d0bbf70314b85e 383 Pfam PF01551 Peptidase family M23 284 377 9.3E-25 T 28-03-2018 IPR016047 Peptidase M23 A6A12_RS01220 9d9f570cde7d8ace23d0bbf70314b85e 383 SUPERFAMILY SSF51261 167 381 1.73E-47 T 28-03-2018 IPR011055 Duplicated hybrid motif A6A12_RS01315 28dfc477057abdec557bf92b7a71e255 326 PIRSF PIRSF005651 1 325 3.1E-94 T 28-03-2018 IPR010200 HflC GO:0016021|GO:0052547 A6A12_RS01315 28dfc477057abdec557bf92b7a71e255 326 SMART SM00244 18 218 1.9E-46 T 28-03-2018 IPR001107 Band 7 domain A6A12_RS01315 28dfc477057abdec557bf92b7a71e255 326 SUPERFAMILY SSF117892 56 142 6.54E-23 T 28-03-2018 IPR001107 Band 7 domain A6A12_RS01315 28dfc477057abdec557bf92b7a71e255 326 SUPERFAMILY SSF117892 173 223 6.54E-23 T 28-03-2018 IPR001107 Band 7 domain A6A12_RS01315 28dfc477057abdec557bf92b7a71e255 326 TIGRFAM TIGR01932 hflC: HflC protein 1 318 1.2E-134 T 28-03-2018 IPR010200 HflC GO:0016021|GO:0052547 A6A12_RS01315 28dfc477057abdec557bf92b7a71e255 326 Pfam PF01145 SPFH domain / Band 7 family 22 233 2.1E-28 T 28-03-2018 IPR001107 Band 7 domain A6A12_RS00475 030ad66a423e2c290e4ccb94051e6dba 138 Pfam PF01914 MarC family integral membrane protein 3 82 4.8E-21 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A6A12_RS12605 d90c25508f616bf306f5775d73aa139a 339 SUPERFAMILY SSF55729 1 337 1.03E-129 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS12605 d90c25508f616bf306f5775d73aa139a 339 Pfam PF04958 Arginine N-succinyltransferase beta subunit 1 337 9.5E-140 T 28-03-2018 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 A6A12_RS12605 d90c25508f616bf306f5775d73aa139a 339 TIGRFAM TIGR03243 arg_catab_AOST: arginine and ornithine succinyltransferase subunits 3 338 5.0E-133 T 28-03-2018 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 A6A12_RS12605 d90c25508f616bf306f5775d73aa139a 339 TIGRFAM TIGR03244 arg_catab_AstA: arginine N-succinyltransferase 3 338 5.4E-134 T 28-03-2018 IPR017650 Arginine N-succinyltransferase GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 A6A12_RS12605 d90c25508f616bf306f5775d73aa139a 339 Gene3D G3DSA:2.40.40.20 278 338 4.3E-15 T 28-03-2018 A6A12_RS12605 d90c25508f616bf306f5775d73aa139a 339 Gene3D G3DSA:3.40.630.30 1 277 1.2E-19 T 28-03-2018 A6A12_RS05410 382a85073bc0810211800dec483ea6a9 469 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 65 83 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 A6A12_RS05410 382a85073bc0810211800dec483ea6a9 469 SUPERFAMILY SSF51366 16 266 4.94E-82 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A6A12_RS05410 382a85073bc0810211800dec483ea6a9 469 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 270 469 29.908 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 A6A12_RS05410 382a85073bc0810211800dec483ea6a9 469 Gene3D G3DSA:3.20.20.70 18 269 1.5E-60 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS05410 382a85073bc0810211800dec483ea6a9 469 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 18 269 35.079 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A6A12_RS05410 382a85073bc0810211800dec483ea6a9 469 Gene3D G3DSA:3.20.20.70 272 469 2.3E-57 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS05410 382a85073bc0810211800dec483ea6a9 469 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 272 464 2.4E-55 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 A6A12_RS05410 382a85073bc0810211800dec483ea6a9 469 Pfam PF00218 Indole-3-glycerol phosphate synthase 20 266 3.9E-97 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A6A12_RS05410 382a85073bc0810211800dec483ea6a9 469 SUPERFAMILY SSF51366 272 467 7.38E-55 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A6A12_RS05770 76f1cd8d2ccb442bd02c7cd0ba327007 237 Pfam PF00072 Response regulator receiver domain 5 113 1.5E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS05770 76f1cd8d2ccb442bd02c7cd0ba327007 237 SUPERFAMILY SSF52172 2 124 4.13E-36 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS05770 76f1cd8d2ccb442bd02c7cd0ba327007 237 Gene3D G3DSA:3.40.50.2300 1 130 4.0E-33 T 28-03-2018 A6A12_RS05770 76f1cd8d2ccb442bd02c7cd0ba327007 237 Gene3D G3DSA:1.10.10.10 131 237 4.0E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05770 76f1cd8d2ccb442bd02c7cd0ba327007 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 234 2.1E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS05770 76f1cd8d2ccb442bd02c7cd0ba327007 237 SUPERFAMILY SSF46894 134 235 5.39E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS05770 76f1cd8d2ccb442bd02c7cd0ba327007 237 SMART SM00862 158 234 3.4E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS05770 76f1cd8d2ccb442bd02c7cd0ba327007 237 SMART SM00448 3 113 4.1E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 PIRSF PIRSF000106 2 560 2.2E-225 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 ProSitePatterns PS00331 Malic enzymes signature. 264 280 - T 28-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 Gene3D G3DSA:3.40.50.10380 12 265 1.3E-113 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 PRINTS PR00072 Malic enzyme signature 144 173 1.9E-72 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 PRINTS PR00072 Malic enzyme signature 264 280 1.9E-72 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 PRINTS PR00072 Malic enzyme signature 295 311 1.9E-72 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 PRINTS PR00072 Malic enzyme signature 180 202 1.9E-72 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 PRINTS PR00072 Malic enzyme signature 239 257 1.9E-72 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 PRINTS PR00072 Malic enzyme signature 405 421 1.9E-72 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 PRINTS PR00072 Malic enzyme signature 84 108 1.9E-72 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 SMART SM00919 268 528 3.1E-133 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 Pfam PF00390 Malic enzyme, N-terminal domain 78 258 5.3E-78 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 SUPERFAMILY SSF53223 4 267 1.51E-109 T 28-03-2018 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 SMART SM01274 78 258 6.2E-108 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 Pfam PF03949 Malic enzyme, NAD binding domain 268 528 8.5E-103 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 Gene3D G3DSA:3.40.50.720 266 562 4.2E-106 T 28-03-2018 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 Hamap MF_01619 NAD-dependent malic enzyme [maeA]. 1 562 72.202 T 28-03-2018 IPR023667 NAD-dependent malic enzyme, proteobacteria GO:0004471|GO:0055114 KEGG: 00620+1.1.1.38 A6A12_RS05515 c41ff2828f27cc8a009ba73a258b69c6 562 SUPERFAMILY SSF51735 268 559 9.6E-95 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS06190 a204391f2db77475597b8add80ebe5a7 235 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 11 229 1.3E-87 T 28-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 A6A12_RS06190 a204391f2db77475597b8add80ebe5a7 235 SUPERFAMILY SSF53335 15 215 1.24E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS06190 a204391f2db77475597b8add80ebe5a7 235 Gene3D G3DSA:3.40.50.150 1 234 6.9E-45 T 28-03-2018 A6A12_RS06190 a204391f2db77475597b8add80ebe5a7 235 Pfam PF13489 Methyltransferase domain 52 201 9.1E-25 T 28-03-2018 A6A12_RS06190 a204391f2db77475597b8add80ebe5a7 235 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 9 235 38.171 T 28-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 A6A12_RS10520 131eeabbe142809d4af339129212f6ec 362 Pfam PF03462 PCRF domain 13 205 2.2E-76 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 A6A12_RS10520 131eeabbe142809d4af339129212f6ec 362 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 359 9.1E-171 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A6A12_RS10520 131eeabbe142809d4af339129212f6ec 362 Gene3D G3DSA:1.20.58.410 2 97 4.8E-20 T 28-03-2018 A6A12_RS10520 131eeabbe142809d4af339129212f6ec 362 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 230 246 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A6A12_RS10520 131eeabbe142809d4af339129212f6ec 362 SMART SM00937 67 180 1.2E-66 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 A6A12_RS10520 131eeabbe142809d4af339129212f6ec 362 SUPERFAMILY SSF75620 12 355 3.27E-137 T 28-03-2018 A6A12_RS10520 131eeabbe142809d4af339129212f6ec 362 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 359 40.586 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 A6A12_RS10520 131eeabbe142809d4af339129212f6ec 362 Pfam PF00472 RF-1 domain 218 323 3.3E-39 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A6A12_RS10520 131eeabbe142809d4af339129212f6ec 362 Gene3D G3DSA:3.30.160.20 211 293 8.0E-33 T 28-03-2018 A6A12_RS01520 2c8bfeb9c51fe883f4c4b865a0192ab2 450 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 6 449 9.1E-124 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS01520 2c8bfeb9c51fe883f4c4b865a0192ab2 450 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 6 449 4.0E-124 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS01520 2c8bfeb9c51fe883f4c4b865a0192ab2 450 SUPERFAMILY SSF55021 298 393 2.11E-18 T 28-03-2018 A6A12_RS01520 2c8bfeb9c51fe883f4c4b865a0192ab2 450 SUPERFAMILY SSF53633 6 292 2.36E-77 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS01520 2c8bfeb9c51fe883f4c4b865a0192ab2 450 ProSitePatterns PS00324 Aspartokinase signature. 6 14 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS01520 2c8bfeb9c51fe883f4c4b865a0192ab2 450 Gene3D G3DSA:3.30.70.260 375 449 6.0E-17 T 28-03-2018 A6A12_RS01520 2c8bfeb9c51fe883f4c4b865a0192ab2 450 SUPERFAMILY SSF55021 375 449 1.26E-14 T 28-03-2018 A6A12_RS01520 2c8bfeb9c51fe883f4c4b865a0192ab2 450 Gene3D G3DSA:3.30.70.260 285 374 2.5E-20 T 28-03-2018 A6A12_RS01520 2c8bfeb9c51fe883f4c4b865a0192ab2 450 Pfam PF00696 Amino acid kinase family 6 278 2.1E-46 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase A6A12_RS01520 2c8bfeb9c51fe883f4c4b865a0192ab2 450 Gene3D G3DSA:3.40.1160.10 3 284 8.6E-63 T 28-03-2018 A6A12_RS01520 2c8bfeb9c51fe883f4c4b865a0192ab2 450 PIRSF PIRSF000726 2 450 1.0E-128 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 A6A12_RS07615 e8c35d275643cb1e95762a1874fb5539 255 Gene3D G3DSA:1.10.287.70 113 168 2.1E-13 T 28-03-2018 A6A12_RS07615 e8c35d275643cb1e95762a1874fb5539 255 Gene3D G3DSA:1.20.5.110 170 206 5.2E-13 T 28-03-2018 A6A12_RS07615 e8c35d275643cb1e95762a1874fb5539 255 SUPERFAMILY SSF81324 21 206 2.07E-38 T 28-03-2018 A6A12_RS07615 e8c35d275643cb1e95762a1874fb5539 255 Pfam PF07885 Ion channel 128 205 2.0E-19 T 28-03-2018 IPR013099 Potassium channel domain A6A12_RS10315 ee15591eee29a5fdd89ddbfeeb01da8f 227 Gene3D G3DSA:3.30.1380.10 6 182 3.5E-32 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A6A12_RS10315 ee15591eee29a5fdd89ddbfeeb01da8f 227 SUPERFAMILY SSF55166 17 175 8.37E-21 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A6A12_RS10315 ee15591eee29a5fdd89ddbfeeb01da8f 227 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 25 176 3.1E-35 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 A6A12_RS09850 16f1a29aa42f07abd0fd45fe93028bd2 161 Pfam PF03100 CcmE 4 136 3.9E-45 T 28-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 A6A12_RS09850 16f1a29aa42f07abd0fd45fe93028bd2 161 SUPERFAMILY SSF82093 30 142 5.36E-39 T 28-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 A6A12_RS09850 16f1a29aa42f07abd0fd45fe93028bd2 161 Gene3D G3DSA:2.40.50.140 27 130 2.1E-31 T 28-03-2018 A6A12_RS09850 16f1a29aa42f07abd0fd45fe93028bd2 161 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 2 146 32.183 T 28-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 A6A12_RS09030 48487fad5dec974ca7b992f344f40609 402 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 402 2.4E-132 T 28-03-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 A6A12_RS09030 48487fad5dec974ca7b992f344f40609 402 Pfam PF02687 FtsX-like permease family 296 395 9.1E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A6A12_RS09030 48487fad5dec974ca7b992f344f40609 402 Pfam PF12704 MacB-like periplasmic core domain 29 204 1.1E-12 T 28-03-2018 IPR025857 MacB-like periplasmic core domain A6A12_RS08560 80c076f7fd60429d6fe2e884ecc2b56e 231 Pfam PF03374 Phage antirepressor protein KilAC domain 119 221 9.4E-24 T 28-03-2018 IPR005039 Antirepressor protein, C-terminal GO:0003677 A6A12_RS08560 80c076f7fd60429d6fe2e884ecc2b56e 231 Pfam PF09669 Phage regulatory protein Rha (Phage_pRha) 11 90 3.5E-17 T 28-03-2018 IPR014054 Bacteriophage regulatory protein, Rha family A6A12_RS04910 aff01c32e0921eff5bf0152498cc9f7f 709 Gene3D G3DSA:1.10.8.60 167 242 1.5E-18 T 28-03-2018 A6A12_RS04910 aff01c32e0921eff5bf0152498cc9f7f 709 SMART SM00382 37 179 1.1E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS04910 aff01c32e0921eff5bf0152498cc9f7f 709 SUPERFAMILY SSF52540 32 223 1.72E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS04910 aff01c32e0921eff5bf0152498cc9f7f 709 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 355 1.1E-132 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 A6A12_RS04910 aff01c32e0921eff5bf0152498cc9f7f 709 SUPERFAMILY SSF48019 243 362 1.62E-32 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A6A12_RS04910 aff01c32e0921eff5bf0152498cc9f7f 709 Pfam PF12168 DNA polymerase III subunits tau domain IV DnaB-binding 490 566 3.5E-22 T 28-03-2018 IPR022001 DNA polymerase III subunit tau, DnaB-binding domain IV KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS04910 aff01c32e0921eff5bf0152498cc9f7f 709 Gene3D G3DSA:1.20.272.10 243 362 8.0E-18 T 28-03-2018 A6A12_RS04910 aff01c32e0921eff5bf0152498cc9f7f 709 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 568 706 1.8E-49 T 28-03-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS04910 aff01c32e0921eff5bf0152498cc9f7f 709 Gene3D G3DSA:3.40.50.300 1 166 6.9E-38 T 28-03-2018 A6A12_RS04910 aff01c32e0921eff5bf0152498cc9f7f 709 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 358 7.7E-31 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 A6A12_RS04910 aff01c32e0921eff5bf0152498cc9f7f 709 Pfam PF13177 DNA polymerase III, delta subunit 20 178 4.7E-44 T 28-03-2018 A6A12_RS09840 b7c767d372fb8353781efe732a43c0fc 183 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 6 177 7.2E-72 T 28-03-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 A6A12_RS09840 b7c767d372fb8353781efe732a43c0fc 183 Gene3D G3DSA:3.40.30.10 20 181 1.5E-27 T 28-03-2018 A6A12_RS09840 b7c767d372fb8353781efe732a43c0fc 183 Pfam PF08534 Redoxin 42 165 4.1E-25 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 A6A12_RS09840 b7c767d372fb8353781efe732a43c0fc 183 ProSitePatterns PS00194 Thioredoxin family active site. 71 89 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A6A12_RS09840 b7c767d372fb8353781efe732a43c0fc 183 SUPERFAMILY SSF52833 46 177 2.25E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS12440 c18beaba3832e93c2ba60dd0bec1fb5d 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12440 c18beaba3832e93c2ba60dd0bec1fb5d 101 SUPERFAMILY SSF57716 2 101 1.64E-36 T 28-03-2018 A6A12_RS12440 c18beaba3832e93c2ba60dd0bec1fb5d 101 Gene3D G3DSA:4.10.830.10 1 101 3.5E-32 T 28-03-2018 A6A12_RS12440 c18beaba3832e93c2ba60dd0bec1fb5d 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 3.6E-24 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12440 c18beaba3832e93c2ba60dd0bec1fb5d 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 25.564 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid A6A12_RS10470 939454f53dc7a800a4d99a4f081fc43b 190 SUPERFAMILY SSF52218 3 187 2.23E-58 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS10470 939454f53dc7a800a4d99a4f081fc43b 190 Gene3D G3DSA:3.40.50.360 1 190 2.2E-43 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS10470 939454f53dc7a800a4d99a4f081fc43b 190 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 3 186 1.3E-40 T 28-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 A6A12_RS10470 939454f53dc7a800a4d99a4f081fc43b 190 Pfam PF03358 NADPH-dependent FMN reductase 4 134 1.2E-12 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A6A12_RS10470 939454f53dc7a800a4d99a4f081fc43b 190 ProSitePatterns PS00201 Flavodoxin signature. 7 23 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 A6A12_RS12545 859b884e4ec51d0d5ec6b57dcdfd65aa 198 Gene3D G3DSA:3.10.50.40 1 170 1.3E-31 T 28-03-2018 A6A12_RS12545 859b884e4ec51d0d5ec6b57dcdfd65aa 198 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 136 1.3E-12 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A6A12_RS12545 859b884e4ec51d0d5ec6b57dcdfd65aa 198 SUPERFAMILY SSF54534 2 140 1.41E-35 T 28-03-2018 A6A12_RS04855 7be37531b4b6cb917b9e4324e79ea7e9 182 Pfam PF08281 Sigma-70, region 4 114 166 4.7E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS04855 7be37531b4b6cb917b9e4324e79ea7e9 182 Gene3D G3DSA:1.10.10.10 106 182 2.3E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS04855 7be37531b4b6cb917b9e4324e79ea7e9 182 Gene3D G3DSA:1.10.1740.10 11 92 1.7E-18 T 28-03-2018 A6A12_RS04855 7be37531b4b6cb917b9e4324e79ea7e9 182 SUPERFAMILY SSF88946 18 99 8.24E-20 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS04855 7be37531b4b6cb917b9e4324e79ea7e9 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 170 2.5E-21 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS04855 7be37531b4b6cb917b9e4324e79ea7e9 182 SUPERFAMILY SSF88659 111 171 1.7E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS04855 7be37531b4b6cb917b9e4324e79ea7e9 182 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 46 77 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS04855 7be37531b4b6cb917b9e4324e79ea7e9 182 Pfam PF04542 Sigma-70 region 2 24 90 1.9E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS07960 f036a9cc3670a5881d41fe14560db891 237 Gene3D G3DSA:1.25.40.10 119 235 6.1E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS07960 f036a9cc3670a5881d41fe14560db891 237 TIGRFAM TIGR02521 type_IV_pilW: type IV pilus biogenesis/stability protein PilW 6 235 3.6E-77 T 28-03-2018 IPR013360 Pilus biogenesis/stability type IV, PilW A6A12_RS07960 f036a9cc3670a5881d41fe14560db891 237 SUPERFAMILY SSF81901 39 193 3.92E-19 T 28-03-2018 A6A12_RS07960 f036a9cc3670a5881d41fe14560db891 237 SMART SM00028 139 172 34.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS07960 f036a9cc3670a5881d41fe14560db891 237 SMART SM00028 35 68 0.11 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS07960 f036a9cc3670a5881d41fe14560db891 237 SMART SM00028 103 136 20.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS07960 f036a9cc3670a5881d41fe14560db891 237 SMART SM00028 69 102 1.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS07960 f036a9cc3670a5881d41fe14560db891 237 Pfam PF13424 Tetratricopeptide repeat 104 169 6.1E-9 T 28-03-2018 A6A12_RS07960 f036a9cc3670a5881d41fe14560db891 237 Gene3D G3DSA:1.25.40.10 97 118 9.8E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS07960 f036a9cc3670a5881d41fe14560db891 237 Pfam PF13174 Tetratricopeptide repeat 72 101 0.034 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS07960 f036a9cc3670a5881d41fe14560db891 237 Gene3D G3DSA:1.25.40.10 27 96 2.8E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS04550 8b8ac39624f4515fbf48a49138352012 554 SUPERFAMILY SSF56235 1 196 7.63E-56 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A6A12_RS04550 8b8ac39624f4515fbf48a49138352012 554 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 373 1.8E-116 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A6A12_RS04550 8b8ac39624f4515fbf48a49138352012 554 Gene3D G3DSA:3.60.20.10 2 191 3.0E-49 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A6A12_RS04550 8b8ac39624f4515fbf48a49138352012 554 Pfam PF13537 Glutamine amidotransferase domain 48 166 3.4E-39 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain A6A12_RS04550 8b8ac39624f4515fbf48a49138352012 554 PIRSF PIRSF001589 1 382 7.1E-105 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A6A12_RS04550 8b8ac39624f4515fbf48a49138352012 554 PIRSF PIRSF001589 363 506 1.7E-27 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A6A12_RS04550 8b8ac39624f4515fbf48a49138352012 554 SUPERFAMILY SSF52402 209 480 3.93E-74 T 28-03-2018 A6A12_RS04550 8b8ac39624f4515fbf48a49138352012 554 Pfam PF00733 Asparagine synthase 211 366 1.8E-56 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A6A12_RS04550 8b8ac39624f4515fbf48a49138352012 554 Gene3D G3DSA:3.40.50.620 192 514 3.3E-86 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS05880 bceda7a6840c29073ed55e1633aec5da 394 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 16 187 1.7E-71 T 28-03-2018 IPR005126 NapC/NirT cytochrome c, N-terminal A6A12_RS05880 bceda7a6840c29073ed55e1633aec5da 394 PIRSF PIRSF000014 1 394 2.6E-163 T 28-03-2018 IPR009154 Membrane-bound tetrahaem cytochrome TorC/YecK GO:0005506|GO:0009055|GO:0009276|GO:0016021|GO:0020037 A6A12_RS05880 bceda7a6840c29073ed55e1633aec5da 394 SUPERFAMILY SSF46626 334 386 8.04E-5 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS05880 bceda7a6840c29073ed55e1633aec5da 394 TIGRFAM TIGR02162 torC: trimethylamine-N-oxide reductase c-type cytochrome TorC 7 394 5.8E-189 T 28-03-2018 IPR009154 Membrane-bound tetrahaem cytochrome TorC/YecK GO:0005506|GO:0009055|GO:0009276|GO:0016021|GO:0020037 A6A12_RS05880 bceda7a6840c29073ed55e1633aec5da 394 SUPERFAMILY SSF48695 12 187 3.96E-58 T 28-03-2018 IPR011031 Multihaem cytochrome A6A12_RS05880 bceda7a6840c29073ed55e1633aec5da 394 Gene3D G3DSA:3.90.10.10 36 74 0.052 T 28-03-2018 A6A12_RS05880 bceda7a6840c29073ed55e1633aec5da 394 Gene3D G3DSA:1.10.760.10 314 393 0.35 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS05880 bceda7a6840c29073ed55e1633aec5da 394 Gene3D G3DSA:1.10.468.10 75 207 1.2E-26 T 28-03-2018 A6A12_RS01405 8fc1ad0278f0f73629ed7db6e6dda373 468 SUPERFAMILY SSF52540 201 272 2.4E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01405 8fc1ad0278f0f73629ed7db6e6dda373 468 SUPERFAMILY SSF52540 299 452 2.4E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01405 8fc1ad0278f0f73629ed7db6e6dda373 468 Gene3D G3DSA:1.10.860.10 14 166 2.2E-46 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal A6A12_RS01405 8fc1ad0278f0f73629ed7db6e6dda373 468 Pfam PF00772 DnaB-like helicase N terminal domain 24 125 1.6E-36 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A6A12_RS01405 8fc1ad0278f0f73629ed7db6e6dda373 468 SUPERFAMILY SSF48024 22 133 2.62E-38 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 A6A12_RS01405 8fc1ad0278f0f73629ed7db6e6dda373 468 SMART SM00382 220 426 0.006 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS01405 8fc1ad0278f0f73629ed7db6e6dda373 468 Pfam PF03796 DnaB-like helicase C terminal domain 203 459 6.7E-114 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 A6A12_RS01405 8fc1ad0278f0f73629ed7db6e6dda373 468 Gene3D G3DSA:3.40.50.300 184 467 2.9E-66 T 28-03-2018 A6A12_RS01405 8fc1ad0278f0f73629ed7db6e6dda373 468 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 24 461 2.7E-177 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 A6A12_RS02645 0ff0f05699b6a53019b53077279f7d4b 255 Gene3D G3DSA:1.20.120.530 80 245 5.8E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A6A12_RS02645 0ff0f05699b6a53019b53077279f7d4b 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 2.8E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A6A12_RS02645 0ff0f05699b6a53019b53077279f7d4b 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 2.8E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A6A12_RS02645 0ff0f05699b6a53019b53077279f7d4b 255 SMART SM00895 99 227 8.2E-18 T 28-03-2018 IPR011711 GntR, C-terminal A6A12_RS02645 0ff0f05699b6a53019b53077279f7d4b 255 Pfam PF07729 FCD domain 99 226 9.0E-17 T 28-03-2018 IPR011711 GntR, C-terminal A6A12_RS02645 0ff0f05699b6a53019b53077279f7d4b 255 SUPERFAMILY SSF48008 98 235 3.14E-19 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A6A12_RS02645 0ff0f05699b6a53019b53077279f7d4b 255 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.4E-25 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A6A12_RS02645 0ff0f05699b6a53019b53077279f7d4b 255 SMART SM00345 15 74 2.8E-27 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A6A12_RS02645 0ff0f05699b6a53019b53077279f7d4b 255 Gene3D G3DSA:1.10.10.10 1 76 1.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS02645 0ff0f05699b6a53019b53077279f7d4b 255 SUPERFAMILY SSF46785 5 76 7.98E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS10915 c88a10128a8ce79553cc4bd931f40338 280 PRINTS PR00599 Methionine aminopeptidase-1 signature 179 191 4.9E-15 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A6A12_RS10915 c88a10128a8ce79553cc4bd931f40338 280 PRINTS PR00599 Methionine aminopeptidase-1 signature 209 221 4.9E-15 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A6A12_RS10915 c88a10128a8ce79553cc4bd931f40338 280 PRINTS PR00599 Methionine aminopeptidase-1 signature 69 82 4.9E-15 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A6A12_RS10915 c88a10128a8ce79553cc4bd931f40338 280 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 185 203 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A6A12_RS10915 c88a10128a8ce79553cc4bd931f40338 280 SUPERFAMILY SSF55920 4 268 1.57E-86 T 28-03-2018 IPR000994 Peptidase M24 A6A12_RS10915 c88a10128a8ce79553cc4bd931f40338 280 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 267 2.5E-89 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A6A12_RS10915 c88a10128a8ce79553cc4bd931f40338 280 Pfam PF00557 Metallopeptidase family M24 13 259 1.8E-51 T 28-03-2018 IPR000994 Peptidase M24 A6A12_RS10915 c88a10128a8ce79553cc4bd931f40338 280 Gene3D G3DSA:3.90.230.10 2 280 8.6E-87 T 28-03-2018 A6A12_RS10915 c88a10128a8ce79553cc4bd931f40338 280 Hamap MF_01974 Methionine aminopeptidase [map]. 3 268 41.228 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 ProSitePatterns PS00755 Protein secY signature 1. 76 95 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 ProSitePatterns PS00756 Protein secY signature 2. 171 188 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 Pfam PF00344 SecY translocase 76 418 2.0E-117 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 Gene3D G3DSA:1.10.3370.10 10 440 6.7E-157 T 28-03-2018 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 371 389 4.4E-96 T 28-03-2018 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 403 421 4.4E-96 T 28-03-2018 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 152 177 4.4E-96 T 28-03-2018 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 178 201 4.4E-96 T 28-03-2018 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 23 41 4.4E-96 T 28-03-2018 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 316 338 4.4E-96 T 28-03-2018 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 116 139 4.4E-96 T 28-03-2018 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 75 95 4.4E-96 T 28-03-2018 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 PRINTS PR00303 Preprotein translocase SecY subunit signature 270 289 4.4E-96 T 28-03-2018 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 PIRSF PIRSF004557 10 442 1.0E-121 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 Hamap MF_01465 Protein translocase subunit SecY [secY]. 9 434 29.227 T 28-03-2018 IPR026593 Protein translocase subunit SecY A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 20 430 4.4E-134 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A6A12_RS12405 0138013a80321b2080c196c8b846e0f0 444 SUPERFAMILY SSF103491 15 425 3.92E-130 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A6A12_RS12650 36e367e5cfc65e62095e6ca6d84b79a7 338 Pfam PF00579 tRNA synthetases class I (W and Y) 3 289 6.1E-77 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS12650 36e367e5cfc65e62095e6ca6d84b79a7 338 SUPERFAMILY SSF52374 5 334 3.06E-91 T 28-03-2018 A6A12_RS12650 36e367e5cfc65e62095e6ca6d84b79a7 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 66 85 5.1E-26 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A6A12_RS12650 36e367e5cfc65e62095e6ca6d84b79a7 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 198 208 5.1E-26 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A6A12_RS12650 36e367e5cfc65e62095e6ca6d84b79a7 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 142 163 5.1E-26 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A6A12_RS12650 36e367e5cfc65e62095e6ca6d84b79a7 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 5.1E-26 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A6A12_RS12650 36e367e5cfc65e62095e6ca6d84b79a7 338 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 334 4.7E-107 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A6A12_RS12650 36e367e5cfc65e62095e6ca6d84b79a7 338 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 335 40.448 T 28-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 A6A12_RS12650 36e367e5cfc65e62095e6ca6d84b79a7 338 Gene3D G3DSA:1.10.240.10 205 317 7.7E-33 T 28-03-2018 A6A12_RS12650 36e367e5cfc65e62095e6ca6d84b79a7 338 Gene3D G3DSA:3.40.50.620 2 204 9.6E-73 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS07340 0911d3805a4fd8fc3ec77b9e4442d18e 506 Gene3D G3DSA:3.20.130.10 314 489 1.4E-67 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A6A12_RS07340 0911d3805a4fd8fc3ec77b9e4442d18e 506 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 324 487 3.4E-50 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A6A12_RS07340 0911d3805a4fd8fc3ec77b9e4442d18e 506 Pfam PF05681 Fumarate hydratase (Fumerase) 11 284 1.0E-98 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A6A12_RS07340 0911d3805a4fd8fc3ec77b9e4442d18e 506 Pfam PF05683 Fumarase C-terminus 288 489 2.7E-82 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A6A12_RS07340 0911d3805a4fd8fc3ec77b9e4442d18e 506 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 12 283 1.9E-62 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A6A12_RS07340 0911d3805a4fd8fc3ec77b9e4442d18e 506 PIRSF PIRSF001394 1 506 1.6E-215 T 28-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 A6A12_RS07340 0911d3805a4fd8fc3ec77b9e4442d18e 506 SUPERFAMILY SSF117457 319 488 5.1E-63 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A6A12_RS05875 2cdeb037b59f4daf11685d5123b51c2e 58 TIGRFAM TIGR02972 TMAO_torE: trimethylamine N-oxide reductase system, TorE protein 8 57 1.4E-28 T 28-03-2018 IPR014316 Trimethylamine N-oxide reductase system, TorE A6A12_RS05875 2cdeb037b59f4daf11685d5123b51c2e 58 Pfam PF06796 Periplasmic nitrate reductase protein NapE 5 55 7.2E-25 T 28-03-2018 IPR010649 Nitrate/trimethylamine N-oxide reductase NapE/TorE A6A12_RS00885 7301ff846fb831d3cc64948743e9cdb0 120 Pfam PF07963 Prokaryotic N-terminal methylation motif 4 28 2.9E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS00885 7301ff846fb831d3cc64948743e9cdb0 120 SUPERFAMILY SSF54523 40 118 1.57E-22 T 28-03-2018 A6A12_RS00885 7301ff846fb831d3cc64948743e9cdb0 120 TIGRFAM TIGR01707 gspI: type II secretion system protein I 10 106 8.4E-36 T 28-03-2018 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 A6A12_RS00885 7301ff846fb831d3cc64948743e9cdb0 120 Pfam PF02501 Type II secretion system (T2SS), protein I 43 118 5.7E-22 T 28-03-2018 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 A6A12_RS00885 7301ff846fb831d3cc64948743e9cdb0 120 Gene3D G3DSA:3.30.1300.30 34 120 3.6E-24 T 28-03-2018 A6A12_RS00885 7301ff846fb831d3cc64948743e9cdb0 120 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 26 2.1E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS04050 32ad300c5469f2353b86b39183307a09 627 ProSitePatterns PS00801 Transketolase signature 1. 36 55 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A6A12_RS04050 32ad300c5469f2353b86b39183307a09 627 SUPERFAMILY SSF52518 8 199 3.57E-76 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS04050 32ad300c5469f2353b86b39183307a09 627 SUPERFAMILY SSF52518 243 381 3.57E-76 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS04050 32ad300c5469f2353b86b39183307a09 627 Pfam PF02779 Transketolase, pyrimidine binding domain 318 479 8.3E-38 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A6A12_RS04050 32ad300c5469f2353b86b39183307a09 627 Pfam PF02780 Transketolase, C-terminal domain 509 617 1.1E-25 T 28-03-2018 IPR033248 Transketolase, C-terminal domain A6A12_RS04050 32ad300c5469f2353b86b39183307a09 627 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 14 282 1.1E-118 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A6A12_RS04050 32ad300c5469f2353b86b39183307a09 627 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 10 626 45.836 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A6A12_RS04050 32ad300c5469f2353b86b39183307a09 627 Gene3D G3DSA:3.40.50.920 495 627 1.3E-34 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A6A12_RS04050 32ad300c5469f2353b86b39183307a09 627 ProSitePatterns PS00802 Transketolase signature 2. 425 441 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A6A12_RS04050 32ad300c5469f2353b86b39183307a09 627 SUPERFAMILY SSF52518 317 502 2.62E-56 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS04050 32ad300c5469f2353b86b39183307a09 627 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 12 625 1.1E-300 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A6A12_RS04050 32ad300c5469f2353b86b39183307a09 627 SUPERFAMILY SSF52922 492 625 7.98E-29 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A6A12_RS04050 32ad300c5469f2353b86b39183307a09 627 Gene3D G3DSA:3.40.50.970 297 488 1.2E-63 T 28-03-2018 A6A12_RS04050 32ad300c5469f2353b86b39183307a09 627 Gene3D G3DSA:3.40.50.970 2 296 2.4E-75 T 28-03-2018 A6A12_RS04050 32ad300c5469f2353b86b39183307a09 627 SMART SM00861 319 483 7.1E-64 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A6A12_RS03245 bbfcbaee71f75c572f1ee9ed2e279c3f 238 SMART SM00448 2 112 3.0E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS03245 bbfcbaee71f75c572f1ee9ed2e279c3f 238 Gene3D G3DSA:3.40.50.2300 1 128 1.0E-30 T 28-03-2018 A6A12_RS03245 bbfcbaee71f75c572f1ee9ed2e279c3f 238 Pfam PF04397 LytTr DNA-binding domain 143 235 1.2E-21 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A6A12_RS03245 bbfcbaee71f75c572f1ee9ed2e279c3f 238 Pfam PF00072 Response regulator receiver domain 5 112 3.1E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS03245 bbfcbaee71f75c572f1ee9ed2e279c3f 238 Gene3D G3DSA:2.20.25.10 200 236 3.3E-7 T 28-03-2018 A6A12_RS03245 bbfcbaee71f75c572f1ee9ed2e279c3f 238 SUPERFAMILY SSF52172 1 124 5.83E-32 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS03245 bbfcbaee71f75c572f1ee9ed2e279c3f 238 Gene3D G3DSA:2.40.50.40 139 198 8.1E-4 T 28-03-2018 A6A12_RS03245 bbfcbaee71f75c572f1ee9ed2e279c3f 238 SMART SM00850 142 236 4.2E-23 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 A6A12_RS06800 1ebcee8a70a34a8a95a0c1fa6f6ace48 529 SUPERFAMILY SSF52540 298 520 1.75E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS06800 1ebcee8a70a34a8a95a0c1fa6f6ace48 529 Gene3D G3DSA:3.40.50.300 283 529 1.7E-45 T 28-03-2018 A6A12_RS06800 1ebcee8a70a34a8a95a0c1fa6f6ace48 529 SUPERFAMILY SSF52540 7 237 7.08E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS06800 1ebcee8a70a34a8a95a0c1fa6f6ace48 529 Pfam PF12848 ABC transporter 224 309 1.6E-20 T 28-03-2018 IPR032781 ABC-transporter extension domain A6A12_RS06800 1ebcee8a70a34a8a95a0c1fa6f6ace48 529 SMART SM00382 343 511 5.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS06800 1ebcee8a70a34a8a95a0c1fa6f6ace48 529 SMART SM00382 26 238 6.4E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS06800 1ebcee8a70a34a8a95a0c1fa6f6ace48 529 Gene3D G3DSA:3.40.50.300 2 282 1.2E-50 T 28-03-2018 A6A12_RS06800 1ebcee8a70a34a8a95a0c1fa6f6ace48 529 Pfam PF00005 ABC transporter 336 466 3.5E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS06800 1ebcee8a70a34a8a95a0c1fa6f6ace48 529 Pfam PF00005 ABC transporter 18 184 8.0E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS06735 2eea590c28d1ec7888ac41671eaea57e 250 SMART SM00419 187 235 4.3E-15 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A6A12_RS06735 2eea590c28d1ec7888ac41671eaea57e 250 SUPERFAMILY SSF51206 23 162 2.23E-31 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like A6A12_RS06735 2eea590c28d1ec7888ac41671eaea57e 250 Pfam PF13545 Crp-like helix-turn-helix domain 168 241 2.5E-17 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A6A12_RS06735 2eea590c28d1ec7888ac41671eaea57e 250 Pfam PF00027 Cyclic nucleotide-binding domain 51 132 5.7E-15 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A6A12_RS06735 2eea590c28d1ec7888ac41671eaea57e 250 SMART SM00100 30 151 1.9E-20 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A6A12_RS06735 2eea590c28d1ec7888ac41671eaea57e 250 Gene3D G3DSA:1.10.10.10 166 250 4.5E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS06735 2eea590c28d1ec7888ac41671eaea57e 250 ProSitePatterns PS00042 Crp-type HTH domain signature. 195 218 - T 28-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 A6A12_RS06735 2eea590c28d1ec7888ac41671eaea57e 250 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 209 224 2.6E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A6A12_RS06735 2eea590c28d1ec7888ac41671eaea57e 250 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 193 209 2.6E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A6A12_RS06735 2eea590c28d1ec7888ac41671eaea57e 250 Gene3D G3DSA:2.60.120.10 24 165 8.3E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS06735 2eea590c28d1ec7888ac41671eaea57e 250 SUPERFAMILY SSF46785 165 244 4.63E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS13180 7b0919336e9e591c8773a563c93b180e 438 SUPERFAMILY SSF56281 1 431 5.17E-120 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS13180 7b0919336e9e591c8773a563c93b180e 438 Pfam PF10996 Beta-Casp domain 233 363 1.0E-24 T 28-03-2018 IPR022712 Beta-Casp domain A6A12_RS13180 7b0919336e9e591c8773a563c93b180e 438 SMART SM01027 233 363 8.0E-53 T 28-03-2018 IPR022712 Beta-Casp domain A6A12_RS13180 7b0919336e9e591c8773a563c93b180e 438 Pfam PF00753 Metallo-beta-lactamase superfamily 14 116 5.3E-12 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS13180 7b0919336e9e591c8773a563c93b180e 438 Gene3D G3DSA:3.60.15.10 2 246 2.5E-50 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS13180 7b0919336e9e591c8773a563c93b180e 438 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 378 436 3.0E-13 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A6A12_RS13180 7b0919336e9e591c8773a563c93b180e 438 SMART SM00849 13 208 1.5E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 Pfam PF01476 LysM domain 412 454 3.3E-11 T 28-03-2018 IPR018392 LysM domain A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 Pfam PF01476 LysM domain 529 571 5.5E-12 T 28-03-2018 IPR018392 LysM domain A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 Pfam PF01476 LysM domain 476 518 5.3E-11 T 28-03-2018 IPR018392 LysM domain A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 SUPERFAMILY SSF54106 528 571 1.44E-9 T 28-03-2018 IPR018392 LysM domain A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 Gene3D G3DSA:3.10.350.10 404 471 2.1E-13 T 28-03-2018 A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 Gene3D G3DSA:3.10.350.10 472 520 1.0E-10 T 28-03-2018 A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 Gene3D G3DSA:3.10.350.10 526 573 2.1E-11 T 28-03-2018 A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 SMART SM00257 528 571 2.6E-13 T 28-03-2018 IPR018392 LysM domain A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 SMART SM00257 475 518 9.0E-12 T 28-03-2018 IPR018392 LysM domain A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 SMART SM00257 411 454 3.8E-14 T 28-03-2018 IPR018392 LysM domain A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 Gene3D G3DSA:3.40.630.40 166 398 1.5E-51 T 28-03-2018 A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 Pfam PF11741 AMIN domain 35 137 2.9E-19 T 28-03-2018 IPR021731 AMIN domain A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 171 390 5.4E-47 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 SUPERFAMILY SSF53187 317 393 6.59E-51 T 28-03-2018 A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 SUPERFAMILY SSF53187 169 265 6.59E-51 T 28-03-2018 A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 SUPERFAMILY SSF54106 474 518 1.06E-9 T 28-03-2018 IPR018392 LysM domain A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 SUPERFAMILY SSF54106 411 454 7.59E-10 T 28-03-2018 IPR018392 LysM domain A6A12_RS01285 147ba42ac5b5b0af69b6344fc4464eb2 573 SMART SM00646 231 390 1.7E-65 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A6A12_RS11425 74b4b88dc0ccc9208cdf1c4da12e6000 470 Gene3D G3DSA:3.40.50.720 147 242 8.2E-16 T 28-03-2018 A6A12_RS11425 74b4b88dc0ccc9208cdf1c4da12e6000 470 SUPERFAMILY SSF51971 145 399 1.24E-67 T 28-03-2018 A6A12_RS11425 74b4b88dc0ccc9208cdf1c4da12e6000 470 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 6 469 1.3E-250 T 28-03-2018 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 A6A12_RS11425 74b4b88dc0ccc9208cdf1c4da12e6000 470 PRINTS PR00419 Adrenodoxin reductase family signature 148 170 1.2E-36 T 28-03-2018 A6A12_RS11425 74b4b88dc0ccc9208cdf1c4da12e6000 470 PRINTS PR00419 Adrenodoxin reductase family signature 213 223 1.2E-36 T 28-03-2018 A6A12_RS11425 74b4b88dc0ccc9208cdf1c4da12e6000 470 PRINTS PR00419 Adrenodoxin reductase family signature 288 302 1.2E-36 T 28-03-2018 A6A12_RS11425 74b4b88dc0ccc9208cdf1c4da12e6000 470 PRINTS PR00419 Adrenodoxin reductase family signature 322 335 1.2E-36 T 28-03-2018 A6A12_RS11425 74b4b88dc0ccc9208cdf1c4da12e6000 470 PRINTS PR00419 Adrenodoxin reductase family signature 171 184 1.2E-36 T 28-03-2018 A6A12_RS11425 74b4b88dc0ccc9208cdf1c4da12e6000 470 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 25 134 1.5E-38 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A6A12_RS11425 74b4b88dc0ccc9208cdf1c4da12e6000 470 Gene3D G3DSA:1.10.1060.10 2 146 5.2E-40 T 28-03-2018 A6A12_RS11425 74b4b88dc0ccc9208cdf1c4da12e6000 470 SUPERFAMILY SSF46548 6 157 1.15E-40 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A6A12_RS11425 74b4b88dc0ccc9208cdf1c4da12e6000 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 147 457 7.1E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS11425 74b4b88dc0ccc9208cdf1c4da12e6000 470 Gene3D G3DSA:3.50.50.60 400 470 6.6E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS11425 74b4b88dc0ccc9208cdf1c4da12e6000 470 Gene3D G3DSA:3.50.50.60 243 311 2.7E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS11425 74b4b88dc0ccc9208cdf1c4da12e6000 470 Gene3D G3DSA:3.50.50.60 312 399 1.6E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS04095 4509f40e2d66a8e3bb2724ae25d118b0 261 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 165 254 8.3E-23 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A6A12_RS04095 4509f40e2d66a8e3bb2724ae25d118b0 261 SUPERFAMILY SSF88723 4 164 2.08E-39 T 28-03-2018 IPR029060 PIN domain-like A6A12_RS04095 4509f40e2d66a8e3bb2724ae25d118b0 261 Gene3D G3DSA:1.10.150.20 178 255 4.7E-19 T 28-03-2018 A6A12_RS04095 4509f40e2d66a8e3bb2724ae25d118b0 261 Hamap MF_01192 Flap endonuclease Xni [xni]. 2 255 45.942 T 28-03-2018 IPR022895 Flap endonuclease Xni GO:0048256 A6A12_RS04095 4509f40e2d66a8e3bb2724ae25d118b0 261 SUPERFAMILY SSF47807 164 253 1.94E-19 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 A6A12_RS04095 4509f40e2d66a8e3bb2724ae25d118b0 261 SMART SM00279 167 202 1.3E-7 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A6A12_RS04095 4509f40e2d66a8e3bb2724ae25d118b0 261 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 158 1.1E-30 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 A6A12_RS04095 4509f40e2d66a8e3bb2724ae25d118b0 261 Gene3D G3DSA:3.40.50.1010 3 177 1.8E-42 T 28-03-2018 IPR029060 PIN domain-like A6A12_RS04095 4509f40e2d66a8e3bb2724ae25d118b0 261 SMART SM00475 3 254 4.2E-64 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 A6A12_RS04570 2c2e081be83e6890b75675609b3589c6 495 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 3 481 7.8E-216 T 28-03-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 A6A12_RS04570 2c2e081be83e6890b75675609b3589c6 495 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 423 440 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A6A12_RS04570 2c2e081be83e6890b75675609b3589c6 495 SUPERFAMILY SSF55604 409 482 1.16E-19 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A6A12_RS04570 2c2e081be83e6890b75675609b3589c6 495 Pfam PF02378 Phosphotransferase system, EIIC 11 324 8.5E-77 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A6A12_RS04570 2c2e081be83e6890b75675609b3589c6 495 Gene3D G3DSA:3.30.1360.60 408 483 3.5E-25 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A6A12_RS04570 2c2e081be83e6890b75675609b3589c6 495 Pfam PF00367 phosphotransferase system, EIIB 412 445 8.6E-12 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A6A12_RS04570 2c2e081be83e6890b75675609b3589c6 495 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 384 470 1.6E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A6A12_RS04560 8844b8de57e5c456242110b401e81594 404 Pfam PF00480 ROK family 86 390 5.7E-73 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A6A12_RS04560 8844b8de57e5c456242110b401e81594 404 ProSitePatterns PS01125 ROK family signature. 217 244 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A6A12_RS04560 8844b8de57e5c456242110b401e81594 404 Gene3D G3DSA:3.30.420.40 206 400 3.1E-46 T 28-03-2018 A6A12_RS04560 8844b8de57e5c456242110b401e81594 404 Gene3D G3DSA:1.10.10.10 14 70 4.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS04560 8844b8de57e5c456242110b401e81594 404 Gene3D G3DSA:3.30.420.40 71 205 1.6E-20 T 28-03-2018 A6A12_RS04560 8844b8de57e5c456242110b401e81594 404 SUPERFAMILY SSF53067 85 392 4.32E-54 T 28-03-2018 A6A12_RS04560 8844b8de57e5c456242110b401e81594 404 SUPERFAMILY SSF46785 11 75 1.36E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS10475 36308c4f04924b4278ee7988061fb78b 145 Pfam PF09842 Predicted membrane protein (DUF2069) 15 117 8.3E-35 T 28-03-2018 IPR018643 Protein of unknown function DUF2069, membrane A6A12_RS10345 8a9190aa78bf6d2b8069f74a47457b8f 470 Gene3D G3DSA:1.10.150.130 35 196 4.2E-4 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A6A12_RS10345 8a9190aa78bf6d2b8069f74a47457b8f 470 SUPERFAMILY SSF56349 236 449 2.65E-23 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS10345 8a9190aa78bf6d2b8069f74a47457b8f 470 SUPERFAMILY SSF56349 164 202 2.65E-23 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS10345 8a9190aa78bf6d2b8069f74a47457b8f 470 Gene3D G3DSA:1.10.443.10 245 466 8.8E-26 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS10345 8a9190aa78bf6d2b8069f74a47457b8f 470 Pfam PF00589 Phage integrase family 254 446 1.7E-13 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS10120 a97ffc96668c13e37f02eb95260f04df 174 Gene3D G3DSA:3.40.50.360 1 174 7.7E-27 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS10120 a97ffc96668c13e37f02eb95260f04df 174 SUPERFAMILY SSF52218 1 173 5.32E-35 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS10120 a97ffc96668c13e37f02eb95260f04df 174 Pfam PF03358 NADPH-dependent FMN reductase 1 140 5.0E-24 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A6A12_RS11780 4506e7b5532b26c5d48c3ee3fb6a5dfc 126 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 87 1.0E-31 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A6A12_RS11780 4506e7b5532b26c5d48c3ee3fb6a5dfc 126 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 2 126 1.1E-44 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A6A12_RS11780 4506e7b5532b26c5d48c3ee3fb6a5dfc 126 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 122 1.6E-25 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A6A12_RS11780 4506e7b5532b26c5d48c3ee3fb6a5dfc 126 SUPERFAMILY SSF56214 3 125 2.75E-32 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A6A12_RS11780 4506e7b5532b26c5d48c3ee3fb6a5dfc 126 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 126 27.431 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A6A12_RS11780 4506e7b5532b26c5d48c3ee3fb6a5dfc 126 Gene3D G3DSA:3.90.470.20 1 126 1.7E-39 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A6A12_RS11780 4506e7b5532b26c5d48c3ee3fb6a5dfc 126 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 126 3.2E-34 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 A6A12_RS12410 56d99e27b7bbe2304e55fdee4017afeb 144 Gene3D G3DSA:3.100.10.10 40 144 5.2E-24 T 28-03-2018 A6A12_RS12410 56d99e27b7bbe2304e55fdee4017afeb 144 ProSitePatterns PS00475 Ribosomal protein L15 signature. 109 139 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12410 56d99e27b7bbe2304e55fdee4017afeb 144 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 4.7E-50 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12410 56d99e27b7bbe2304e55fdee4017afeb 144 SUPERFAMILY SSF52080 4 143 3.92E-46 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P A6A12_RS12410 56d99e27b7bbe2304e55fdee4017afeb 144 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 144 18.967 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 A6A12_RS12410 56d99e27b7bbe2304e55fdee4017afeb 144 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 143 2.8E-31 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P A6A12_RS12070 2999b6ca3fe611f1de42c06bc5ba63b7 155 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 102 150 6.4E-19 T 28-03-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal A6A12_RS12070 2999b6ca3fe611f1de42c06bc5ba63b7 155 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 9 99 5.0E-43 T 28-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A6A12_RS12070 2999b6ca3fe611f1de42c06bc5ba63b7 155 Gene3D G3DSA:3.30.70.140 5 97 1.4E-33 T 28-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A6A12_RS12070 2999b6ca3fe611f1de42c06bc5ba63b7 155 SUPERFAMILY SSF57825 101 151 6.93E-16 T 28-03-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal A6A12_RS12070 2999b6ca3fe611f1de42c06bc5ba63b7 155 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 4 152 33.35 T 28-03-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A6A12_RS12070 2999b6ca3fe611f1de42c06bc5ba63b7 155 Gene3D G3DSA:2.30.30.20 102 150 1.2E-17 T 28-03-2018 A6A12_RS12070 2999b6ca3fe611f1de42c06bc5ba63b7 155 SUPERFAMILY SSF54893 2 100 1.24E-35 T 28-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A6A12_RS12070 2999b6ca3fe611f1de42c06bc5ba63b7 155 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 5 150 1.4E-60 T 28-03-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A6A12_RS12070 2999b6ca3fe611f1de42c06bc5ba63b7 155 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 7 97 3.7E-30 T 28-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A6A12_RS08455 4065874480a790978350b22fde2b0aa0 572 Pfam PF03354 Phage Terminase 84 551 5.1E-69 T 28-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type A6A12_RS02565 a79616bedf6e1d0bec5f1ddf42974ba4 184 SUPERFAMILY SSF50447 15 102 1.17E-23 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A6A12_RS02565 a79616bedf6e1d0bec5f1ddf42974ba4 184 SUPERFAMILY SSF50346 108 182 1.77E-19 T 28-03-2018 IPR011033 PRC-barrel-like A6A12_RS02565 a79616bedf6e1d0bec5f1ddf42974ba4 184 Gene3D G3DSA:2.40.30.60 14 102 6.6E-26 T 28-03-2018 IPR002676 RimM protein GO:0006364 A6A12_RS02565 a79616bedf6e1d0bec5f1ddf42974ba4 184 Gene3D G3DSA:2.30.30.240 104 179 1.7E-21 T 28-03-2018 A6A12_RS02565 a79616bedf6e1d0bec5f1ddf42974ba4 184 Pfam PF05239 PRC-barrel domain 106 179 4.1E-13 T 28-03-2018 IPR027275 PRC-barrel domain A6A12_RS02565 a79616bedf6e1d0bec5f1ddf42974ba4 184 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 16 183 8.5E-56 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A6A12_RS02565 a79616bedf6e1d0bec5f1ddf42974ba4 184 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 15 184 23.673 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 A6A12_RS02565 a79616bedf6e1d0bec5f1ddf42974ba4 184 Pfam PF01782 RimM N-terminal domain 18 97 3.8E-25 T 28-03-2018 IPR002676 RimM protein GO:0006364 A6A12_RS07170 221b2a5a4996e8668e64d5ee7aff8280 1311 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 24 1309 0.0 T 28-03-2018 IPR010222 RNA helicase HrpA GO:0004004 A6A12_RS07170 221b2a5a4996e8668e64d5ee7aff8280 1311 SMART SM00847 473 572 1.7E-35 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 A6A12_RS07170 221b2a5a4996e8668e64d5ee7aff8280 1311 Pfam PF04408 Helicase associated domain (HA2) 475 570 1.6E-18 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 A6A12_RS07170 221b2a5a4996e8668e64d5ee7aff8280 1311 Gene3D G3DSA:3.40.50.300 86 245 4.6E-31 T 28-03-2018 A6A12_RS07170 221b2a5a4996e8668e64d5ee7aff8280 1311 Pfam PF00270 DEAD/DEAH box helicase 97 243 6.1E-8 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A6A12_RS07170 221b2a5a4996e8668e64d5ee7aff8280 1311 Pfam PF00271 Helicase conserved C-terminal domain 298 412 1.3E-10 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS07170 221b2a5a4996e8668e64d5ee7aff8280 1311 Gene3D G3DSA:3.40.50.300 263 433 3.0E-44 T 28-03-2018 A6A12_RS07170 221b2a5a4996e8668e64d5ee7aff8280 1311 SMART SM00487 82 269 5.2E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS07170 221b2a5a4996e8668e64d5ee7aff8280 1311 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 635 711 1.6E-21 T 28-03-2018 IPR011709 Domain of unknown function DUF1605 A6A12_RS07170 221b2a5a4996e8668e64d5ee7aff8280 1311 SUPERFAMILY SSF52540 84 614 1.28E-111 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS07170 221b2a5a4996e8668e64d5ee7aff8280 1311 Pfam PF11898 Domain of unknown function (DUF3418) 725 1309 7.0E-231 T 28-03-2018 IPR024590 RNA helicase HrpA, C-terminal A6A12_RS07170 221b2a5a4996e8668e64d5ee7aff8280 1311 SMART SM00490 313 413 8.9E-14 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS07170 221b2a5a4996e8668e64d5ee7aff8280 1311 SMART SM00382 102 393 1.3E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS12890 09a9b793c286314d37c732ede38d3d39 188 PIRSF PIRSF039093 1 175 2.5E-87 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 A6A12_RS12890 09a9b793c286314d37c732ede38d3d39 188 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 1 172 41.89 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 A6A12_RS12890 09a9b793c286314d37c732ede38d3d39 188 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 2 172 2.2E-86 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 A6A12_RS12890 09a9b793c286314d37c732ede38d3d39 188 SUPERFAMILY SSF56235 2 172 1.49E-57 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A6A12_RS12890 09a9b793c286314d37c732ede38d3d39 188 Pfam PF00227 Proteasome subunit 2 167 1.2E-23 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A6A12_RS12890 09a9b793c286314d37c732ede38d3d39 188 Gene3D G3DSA:3.60.20.10 2 173 1.2E-30 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 SUPERFAMILY SSF52374 11 146 1.15E-100 T 28-03-2018 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 SUPERFAMILY SSF52374 181 392 1.15E-100 T 28-03-2018 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 Pfam PF09334 tRNA synthetases class I (M) 14 401 3.5E-165 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 Hamap MF_00098 Methionine--tRNA ligase [metG]. 11 550 41.344 T 28-03-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 Gene3D G3DSA:2.170.220.10 186 253 4.2E-14 T 28-03-2018 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 Gene3D G3DSA:1.10.730.10 378 541 7.7E-34 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 20 31 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 548 687 1.4E-46 T 28-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 15 28 5.6E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 296 311 5.6E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 47 61 5.6E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 256 267 5.6E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 389 400 5.6E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 95 106 5.6E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 SUPERFAMILY SSF50249 586 687 3.18E-34 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 Gene3D G3DSA:2.20.28.20 147 180 3.3E-16 T 28-03-2018 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 Pfam PF01588 Putative tRNA binding domain 593 685 2.2E-26 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 Gene3D G3DSA:3.40.50.620 254 373 1.6E-22 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 14 540 5.5E-201 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 SUPERFAMILY SSF47323 394 552 1.25E-44 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 Gene3D G3DSA:2.40.50.140 579 688 4.0E-32 T 28-03-2018 A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 Gene3D G3DSA:3.40.50.620 10 135 5.2E-24 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS04815 43b168dbdf7fa08c36560997c96bd3b1 688 SUPERFAMILY SSF57770 147 181 5.89E-13 T 28-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A6A12_RS03525 2a54925aa5f667ad11df6a41b54cb7ea 112 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 110 1.3E-59 T 28-03-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 A6A12_RS03525 2a54925aa5f667ad11df6a41b54cb7ea 112 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 28-03-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A6A12_RS03525 2a54925aa5f667ad11df6a41b54cb7ea 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 91 1.6E-14 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A6A12_RS03525 2a54925aa5f667ad11df6a41b54cb7ea 112 PRINTS PR00355 Adrenodoxin signature 42 52 3.7E-10 T 28-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A6A12_RS03525 2a54925aa5f667ad11df6a41b54cb7ea 112 PRINTS PR00355 Adrenodoxin signature 83 91 3.7E-10 T 28-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A6A12_RS03525 2a54925aa5f667ad11df6a41b54cb7ea 112 PRINTS PR00355 Adrenodoxin signature 60 74 3.7E-10 T 28-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 A6A12_RS03525 2a54925aa5f667ad11df6a41b54cb7ea 112 Gene3D G3DSA:3.10.20.30 9 112 1.1E-31 T 28-03-2018 IPR012675 Beta-grasp domain A6A12_RS03525 2a54925aa5f667ad11df6a41b54cb7ea 112 SUPERFAMILY SSF54292 4 105 1.57E-32 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A6A12_RS10645 bc0822802053b4eae271b34f04028868 138 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site A6A12_RS10645 bc0822802053b4eae271b34f04028868 138 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 92 136 4.3E-12 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A6A12_RS10645 bc0822802053b4eae271b34f04028868 138 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 138 6.2E-52 T 28-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 A6A12_RS10645 bc0822802053b4eae271b34f04028868 138 Pfam PF00460 Flagella basal body rod protein 7 32 1.8E-7 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A6A12_RS08775 992c3123418abdc8c6b475fb679a0e4d 353 SUPERFAMILY SSF142754 29 341 1.44E-105 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A6A12_RS08775 992c3123418abdc8c6b475fb679a0e4d 353 Pfam PF02445 Quinolinate synthetase A protein 32 340 7.2E-102 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A6A12_RS08775 992c3123418abdc8c6b475fb679a0e4d 353 Gene3D G3DSA:3.40.50.10800 209 323 6.2E-32 T 28-03-2018 A6A12_RS08775 992c3123418abdc8c6b475fb679a0e4d 353 Hamap MF_00567 Quinolinate synthase A [nadA]. 1 347 66.433 T 28-03-2018 IPR023513 Quinolinate synthase A, type 1 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A6A12_RS08775 992c3123418abdc8c6b475fb679a0e4d 353 Gene3D G3DSA:3.40.50.10800 115 208 1.9E-20 T 28-03-2018 A6A12_RS08775 992c3123418abdc8c6b475fb679a0e4d 353 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 28 341 2.2E-114 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A6A12_RS08775 992c3123418abdc8c6b475fb679a0e4d 353 Gene3D G3DSA:3.40.50.10800 25 110 5.5E-19 T 28-03-2018 A6A12_RS02010 3c6ad3438e3728964ebe8bc885229398 287 Pfam PF00924 Mechanosensitive ion channel 77 274 1.6E-62 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A6A12_RS02010 3c6ad3438e3728964ebe8bc885229398 287 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 149 183 - T 28-03-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 A6A12_RS02010 3c6ad3438e3728964ebe8bc885229398 287 Gene3D G3DSA:3.30.70.100 186 279 6.8E-31 T 28-03-2018 A6A12_RS02010 3c6ad3438e3728964ebe8bc885229398 287 SUPERFAMILY SSF50182 120 185 6.87E-19 T 28-03-2018 IPR010920 LSM domain A6A12_RS02010 3c6ad3438e3728964ebe8bc885229398 287 SUPERFAMILY SSF82689 186 284 4.45E-35 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A6A12_RS02010 3c6ad3438e3728964ebe8bc885229398 287 Pfam PF05552 Conserved TM helix 21 69 1.3E-11 T 28-03-2018 IPR008910 Conserved TM helix A6A12_RS02010 3c6ad3438e3728964ebe8bc885229398 287 SUPERFAMILY SSF82861 33 118 7.06E-17 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A6A12_RS02010 3c6ad3438e3728964ebe8bc885229398 287 Gene3D G3DSA:2.30.30.60 135 185 8.5E-19 T 28-03-2018 A6A12_RS08900 d8029b49352f56a1e78f3adbf81e3711 705 Pfam PF02743 Cache domain 49 324 6.7E-16 T 28-03-2018 IPR033479 Double Cache domain 1 A6A12_RS08900 d8029b49352f56a1e78f3adbf81e3711 705 Pfam PF00672 HAMP domain 375 425 3.0E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS08900 d8029b49352f56a1e78f3adbf81e3711 705 Gene3D G3DSA:1.10.287.950 461 676 2.4E-43 T 28-03-2018 A6A12_RS08900 d8029b49352f56a1e78f3adbf81e3711 705 SUPERFAMILY SSF58104 396 705 1.12E-69 T 28-03-2018 A6A12_RS08900 d8029b49352f56a1e78f3adbf81e3711 705 Gene3D G3DSA:3.30.450.20 89 219 1.9E-8 T 28-03-2018 A6A12_RS08900 d8029b49352f56a1e78f3adbf81e3711 705 SMART SM00283 443 704 1.2E-62 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS08900 d8029b49352f56a1e78f3adbf81e3711 705 Gene3D G3DSA:1.10.287.1060 367 460 4.2E-4 T 28-03-2018 A6A12_RS08900 d8029b49352f56a1e78f3adbf81e3711 705 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 515 671 5.7E-41 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS08900 d8029b49352f56a1e78f3adbf81e3711 705 Gene3D G3DSA:3.30.450.20 220 342 8.6E-12 T 28-03-2018 A6A12_RS08900 d8029b49352f56a1e78f3adbf81e3711 705 SMART SM00304 374 428 6.2E-15 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS03255 fa0639153c0d3de0e795ae1aac43fec3 359 SUPERFAMILY SSF51569 8 345 5.4E-139 T 28-03-2018 A6A12_RS03255 fa0639153c0d3de0e795ae1aac43fec3 359 PIRSF PIRSF001361 1 354 5.5E-164 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A6A12_RS03255 fa0639153c0d3de0e795ae1aac43fec3 359 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 10 346 1.0E-162 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A6A12_RS03255 fa0639153c0d3de0e795ae1aac43fec3 359 Pfam PF00793 DAHP synthetase I family 41 340 8.7E-105 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A6A12_RS03255 fa0639153c0d3de0e795ae1aac43fec3 359 Gene3D G3DSA:3.20.20.70 9 354 8.6E-129 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS08215 1e834e916de47931dd132a068827b656 237 SUPERFAMILY SSF64288 96 232 2.04E-37 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A6A12_RS08215 1e834e916de47931dd132a068827b656 237 SMART SM00345 10 69 7.2E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A6A12_RS08215 1e834e916de47931dd132a068827b656 237 Gene3D G3DSA:3.40.1410.10 77 235 2.7E-36 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A6A12_RS08215 1e834e916de47931dd132a068827b656 237 SUPERFAMILY SSF46785 2 73 2.53E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS08215 1e834e916de47931dd132a068827b656 237 Pfam PF07702 UTRA domain 92 229 2.0E-32 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A6A12_RS08215 1e834e916de47931dd132a068827b656 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 69 1.8E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A6A12_RS08215 1e834e916de47931dd132a068827b656 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 3.9E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A6A12_RS08215 1e834e916de47931dd132a068827b656 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 3.9E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A6A12_RS08215 1e834e916de47931dd132a068827b656 237 TIGRFAM TIGR02018 his_ut_repres: histidine utilization repressor 5 234 2.0E-94 T 28-03-2018 IPR010248 Histidine utilization repressor GO:0003677|GO:0006547|GO:0045892 A6A12_RS08215 1e834e916de47931dd132a068827b656 237 Gene3D G3DSA:1.10.10.10 1 76 5.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS08215 1e834e916de47931dd132a068827b656 237 SMART SM00866 92 229 3.5E-32 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 A6A12_RS02120 72b2f0abbb582e05c7e9a7f8ed26a986 303 Pfam PF00476 DNA polymerase family A 84 291 2.3E-18 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS02120 72b2f0abbb582e05c7e9a7f8ed26a986 303 SMART SM00482 83 259 6.8E-7 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS02120 72b2f0abbb582e05c7e9a7f8ed26a986 303 Gene3D G3DSA:1.10.150.20 102 235 6.7E-11 T 28-03-2018 A6A12_RS02120 72b2f0abbb582e05c7e9a7f8ed26a986 303 SUPERFAMILY SSF56672 33 287 1.89E-28 T 28-03-2018 A6A12_RS06120 d2427d036f3c9966ae6b73dbe7012980 377 Gene3D G3DSA:2.40.370.10 255 376 1.2E-20 T 28-03-2018 IPR023374 AttH-like domain A6A12_RS06120 d2427d036f3c9966ae6b73dbe7012980 377 Pfam PF17186 Lipocalin-like domain 255 375 2.2E-23 T 28-03-2018 A6A12_RS06120 d2427d036f3c9966ae6b73dbe7012980 377 SUPERFAMILY SSF159245 57 375 7.06E-77 T 28-03-2018 A6A12_RS06120 d2427d036f3c9966ae6b73dbe7012980 377 Gene3D G3DSA:2.40.370.10 68 254 1.1E-44 T 28-03-2018 IPR023374 AttH-like domain A6A12_RS06120 d2427d036f3c9966ae6b73dbe7012980 377 Pfam PF07143 CrtC N-terminal lipocalin domain 80 251 8.8E-42 T 28-03-2018 IPR010791 AttH domain A6A12_RS05095 8c1726bc0eb003e27c13d12a62a02026 447 SUPERFAMILY SSF52343 316 446 2.88E-19 T 28-03-2018 A6A12_RS05095 8c1726bc0eb003e27c13d12a62a02026 447 Pfam PF01794 Ferric reductase like transmembrane component 47 184 1.2E-18 T 28-03-2018 IPR013130 Ferric reductase transmembrane component-like domain A6A12_RS05095 8c1726bc0eb003e27c13d12a62a02026 447 Pfam PF08022 FAD-binding domain 242 318 5.0E-8 T 28-03-2018 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 A6A12_RS05095 8c1726bc0eb003e27c13d12a62a02026 447 SUPERFAMILY SSF63380 240 320 4.0E-15 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A6A12_RS05095 8c1726bc0eb003e27c13d12a62a02026 447 Gene3D G3DSA:3.40.50.80 321 444 1.1E-12 T 28-03-2018 A6A12_RS05095 8c1726bc0eb003e27c13d12a62a02026 447 Gene3D G3DSA:2.40.30.10 223 319 8.4E-15 T 28-03-2018 A6A12_RS12090 9444da2cd19aa08d9571bfaf8861a558 248 Pfam PF01553 Acyltransferase 57 180 5.5E-29 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A6A12_RS12090 9444da2cd19aa08d9571bfaf8861a558 248 SUPERFAMILY SSF69593 6 236 1.96E-57 T 28-03-2018 A6A12_RS12090 9444da2cd19aa08d9571bfaf8861a558 248 Gene3D G3DSA:3.40.1130.10 30 248 1.3E-40 T 28-03-2018 A6A12_RS12090 9444da2cd19aa08d9571bfaf8861a558 248 SMART SM00563 67 182 3.0E-38 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A6A12_RS12090 9444da2cd19aa08d9571bfaf8861a558 248 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 50 180 1.1E-42 T 28-03-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 A6A12_RS05005 754f20c40d61f8026dd15f6af00f4a36 233 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 5 221 2.7E-67 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 A6A12_RS05005 754f20c40d61f8026dd15f6af00f4a36 233 Pfam PF00814 Glycoprotease family 30 156 3.4E-31 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A6A12_RS05005 754f20c40d61f8026dd15f6af00f4a36 233 SUPERFAMILY SSF53067 4 105 1.29E-31 T 28-03-2018 A6A12_RS05005 754f20c40d61f8026dd15f6af00f4a36 233 Gene3D G3DSA:3.30.420.40 106 190 5.1E-24 T 28-03-2018 A6A12_RS05005 754f20c40d61f8026dd15f6af00f4a36 233 Gene3D G3DSA:3.30.420.40 1 105 1.1E-14 T 28-03-2018 A6A12_RS05005 754f20c40d61f8026dd15f6af00f4a36 233 SUPERFAMILY SSF53067 111 219 4.27E-26 T 28-03-2018 A6A12_RS13040 4254a5418241483f0ed70e67b0c2d6ca 600 Pfam PF13899 Thioredoxin-like 489 552 1.5E-12 T 28-03-2018 A6A12_RS13040 4254a5418241483f0ed70e67b0c2d6ca 600 Pfam PF11412 Disulphide bond corrector protein DsbC 42 152 5.7E-31 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain A6A12_RS13040 4254a5418241483f0ed70e67b0c2d6ca 600 SUPERFAMILY SSF74863 40 154 6.93E-41 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain A6A12_RS13040 4254a5418241483f0ed70e67b0c2d6ca 600 SUPERFAMILY SSF52833 482 595 4.14E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS13040 4254a5418241483f0ed70e67b0c2d6ca 600 Gene3D G3DSA:2.60.40.1250 37 162 3.7E-35 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain A6A12_RS13040 4254a5418241483f0ed70e67b0c2d6ca 600 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 206 406 2.6E-18 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 A6A12_RS13040 4254a5418241483f0ed70e67b0c2d6ca 600 ProSitePatterns PS00194 Thioredoxin family active site. 507 525 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A6A12_RS13040 4254a5418241483f0ed70e67b0c2d6ca 600 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 1 599 38.426 T 28-03-2018 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 A6A12_RS13040 4254a5418241483f0ed70e67b0c2d6ca 600 Gene3D G3DSA:3.40.30.10 469 596 1.8E-18 T 28-03-2018 A6A12_RS05645 c270a140bd095f8615792d8202ed6787 346 Gene3D G3DSA:3.90.1150.10 1 61 0.0029 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS05645 c270a140bd095f8615792d8202ed6787 346 Pfam PF00155 Aminotransferase class I and II 42 338 3.2E-54 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A6A12_RS05645 c270a140bd095f8615792d8202ed6787 346 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 6 343 2.7E-119 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A6A12_RS05645 c270a140bd095f8615792d8202ed6787 346 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 345 53.417 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 A6A12_RS05645 c270a140bd095f8615792d8202ed6787 346 Gene3D G3DSA:3.40.640.10 62 239 3.0E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS05645 c270a140bd095f8615792d8202ed6787 346 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 206 215 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 A6A12_RS05645 c270a140bd095f8615792d8202ed6787 346 SUPERFAMILY SSF53383 14 344 8.94E-74 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS05645 c270a140bd095f8615792d8202ed6787 346 Gene3D G3DSA:3.90.1150.10 240 346 3.5E-12 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS10890 f70ec470f8d68b2d5fc60bd6a4b87ebd 251 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 184 201 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 A6A12_RS10890 f70ec470f8d68b2d5fc60bd6a4b87ebd 251 Gene3D G3DSA:3.40.1180.10 1 241 8.0E-92 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A6A12_RS10890 f70ec470f8d68b2d5fc60bd6a4b87ebd 251 SUPERFAMILY SSF64005 10 234 2.35E-86 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A6A12_RS10890 f70ec470f8d68b2d5fc60bd6a4b87ebd 251 Pfam PF01255 Putative undecaprenyl diphosphate synthase 18 238 3.6E-80 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A6A12_RS10890 f70ec470f8d68b2d5fc60bd6a4b87ebd 251 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 11 238 2.4E-93 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A6A12_RS10890 f70ec470f8d68b2d5fc60bd6a4b87ebd 251 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 11 239 39.197 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A6A12_RS02675 a52be7776754fc9a9fd97b311d8a37cd 222 SUPERFAMILY SSF53056 2 214 2.35E-75 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A6A12_RS02675 a52be7776754fc9a9fd97b311d8a37cd 222 SMART SM00947 30 192 2.9E-65 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A6A12_RS02675 a52be7776754fc9a9fd97b311d8a37cd 222 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A6A12_RS02675 a52be7776754fc9a9fd97b311d8a37cd 222 Gene3D G3DSA:3.40.1050.10 1 220 8.4E-76 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A6A12_RS02675 a52be7776754fc9a9fd97b311d8a37cd 222 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 42 49 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A6A12_RS02675 a52be7776754fc9a9fd97b311d8a37cd 222 Pfam PF00484 Carbonic anhydrase 38 188 8.1E-50 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 A6A12_RS01550 d3a96bf109c411610790bd9a99c8d8ef 940 Gene3D G3DSA:3.40.50.300 425 609 1.1E-21 T 28-03-2018 A6A12_RS01550 d3a96bf109c411610790bd9a99c8d8ef 940 ProSitePatterns PS00211 ABC transporters family signature. 829 843 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS01550 d3a96bf109c411610790bd9a99c8d8ef 940 Pfam PF00005 ABC transporter 622 859 2.1E-8 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS01550 d3a96bf109c411610790bd9a99c8d8ef 940 Gene3D G3DSA:3.30.190.20 138 247 5.0E-42 T 28-03-2018 A6A12_RS01550 d3a96bf109c411610790bd9a99c8d8ef 940 ProSitePatterns PS00211 ABC transporters family signature. 486 500 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS01550 d3a96bf109c411610790bd9a99c8d8ef 940 SUPERFAMILY SSF52540 620 912 2.04E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01550 d3a96bf109c411610790bd9a99c8d8ef 940 Gene3D G3DSA:3.40.50.300 610 938 2.9E-53 T 28-03-2018 A6A12_RS01550 d3a96bf109c411610790bd9a99c8d8ef 940 Gene3D G3DSA:1.10.8.280 284 404 3.8E-38 T 28-03-2018 A6A12_RS01550 d3a96bf109c411610790bd9a99c8d8ef 940 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 939 22.882 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 A6A12_RS01550 d3a96bf109c411610790bd9a99c8d8ef 940 SUPERFAMILY SSF52540 429 568 2.21E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01550 d3a96bf109c411610790bd9a99c8d8ef 940 SUPERFAMILY SSF52540 4 204 2.21E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01550 d3a96bf109c411610790bd9a99c8d8ef 940 Gene3D G3DSA:3.40.50.300 3 34 0.011 T 28-03-2018 A6A12_RS01550 d3a96bf109c411610790bd9a99c8d8ef 940 Gene3D G3DSA:3.40.50.300 35 137 1.6E-4 T 28-03-2018 A6A12_RS01550 d3a96bf109c411610790bd9a99c8d8ef 940 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 3 924 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 656 736 6.5E-24 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 Gene3D G3DSA:1.10.1780.10 1 143 4.4E-27 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 SMART SM00382 209 354 1.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 SMART SM00382 490 657 1.7E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 SUPERFAMILY SSF81923 1 142 1.7E-59 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 62 8.1E-13 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 214 327 6.9E-12 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 Pfam PF07724 AAA domain (Cdc48 subfamily) 489 650 6.5E-47 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 305 317 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 SMART SM01086 656 745 2.7E-36 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 494 512 6.9E-36 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 536 554 6.9E-36 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 565 583 6.9E-36 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 598 612 6.9E-36 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 Gene3D G3DSA:1.10.8.60 656 755 1.7E-22 T 28-03-2018 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 Gene3D G3DSA:3.40.50.300 454 655 3.2E-38 T 28-03-2018 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 Gene3D G3DSA:1.10.8.60 354 453 3.5E-27 T 28-03-2018 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 Gene3D G3DSA:3.40.50.300 168 353 2.3E-25 T 28-03-2018 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 SUPERFAMILY SSF52540 440 744 1.12E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 SUPERFAMILY SSF52540 171 429 4.34E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 737 0.0 T 28-03-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 A6A12_RS05695 ca5b19e37a19f77b6ae38df5a6e21df0 756 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 521 539 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 A6A12_RS11585 fe96479a8e0ea6e3497c3b4daf6510d3 122 Gene3D G3DSA:3.40.1350.10 13 122 1.6E-31 T 28-03-2018 A6A12_RS11585 fe96479a8e0ea6e3497c3b4daf6510d3 122 Pfam PF02021 Uncharacterised protein family UPF0102 13 105 1.5E-25 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 A6A12_RS11585 fe96479a8e0ea6e3497c3b4daf6510d3 122 SUPERFAMILY SSF52980 8 108 1.39E-21 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A6A12_RS11585 fe96479a8e0ea6e3497c3b4daf6510d3 122 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 7 120 2.8E-33 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 A6A12_RS11585 fe96479a8e0ea6e3497c3b4daf6510d3 122 Hamap MF_00048 UPF0102 protein YraN [yraN]. 6 118 22.015 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 20 238 7.9E-84 T 28-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 SUPERFAMILY SSF88659 161 240 2.06E-20 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 Pfam PF04545 Sigma-70, region 4 187 234 3.2E-18 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 SUPERFAMILY SSF88659 92 165 5.23E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 SUPERFAMILY SSF88946 6 91 1.7E-23 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. 5 240 61.805 T 28-03-2018 IPR028617 RNA polymerase sigma factor FliA GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 PRINTS PR00046 Major sigma-70 factor signature 222 233 5.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 PRINTS PR00046 Major sigma-70 factor signature 46 59 5.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 PRINTS PR00046 Major sigma-70 factor signature 190 202 5.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 PRINTS PR00046 Major sigma-70 factor signature 207 222 5.3E-12 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 Pfam PF04539 Sigma-70 region 3 100 171 2.8E-12 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 Pfam PF04542 Sigma-70 region 2 20 91 3.7E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 Gene3D G3DSA:1.10.10.10 92 139 5.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 PIRSF PIRSF000770 3 243 2.4E-35 T 28-03-2018 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 Gene3D G3DSA:1.10.1740.10 3 89 2.1E-20 T 28-03-2018 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 237 3.1E-31 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS09915 12caac431f3c7d03b2c0fe728f198d78 244 Gene3D G3DSA:1.10.10.10 155 240 1.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 PRINTS PR00987 Glutamyl-tRNA synthetase signature 60 73 6.0E-10 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 PRINTS PR00987 Glutamyl-tRNA synthetase signature 31 43 6.0E-10 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 PRINTS PR00987 Glutamyl-tRNA synthetase signature 45 56 6.0E-10 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 220 6.0E-10 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 34 45 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 SUPERFAMILY SSF52374 11 337 5.09E-103 T 28-03-2018 A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 28 337 4.1E-128 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 340 529 1.8E-61 T 28-03-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 Gene3D G3DSA:3.40.50.620 6 41 0.0078 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 Gene3D G3DSA:1.10.1160.10 261 338 7.9E-37 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 550 54.067 T 28-03-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 Gene3D G3DSA:2.40.240.10 344 464 1.7E-47 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 SUPERFAMILY SSF50715 340 548 2.88E-78 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 Gene3D G3DSA:3.40.50.620 155 260 1.9E-21 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 Gene3D G3DSA:3.40.50.620 42 154 4.9E-41 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 Gene3D G3DSA:2.40.240.10 465 548 2.5E-31 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A6A12_RS04575 044b88790d0ca927d94f1458bd32099e 556 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 28 552 1.3E-294 T 28-03-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A6A12_RS11240 5d0e17f778dfb4ef4f0f36916b27a073 350 Gene3D G3DSA:3.30.428.10 167 350 9.6E-55 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 A6A12_RS11240 5d0e17f778dfb4ef4f0f36916b27a073 350 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 4 349 5.1E-183 T 28-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 A6A12_RS11240 5d0e17f778dfb4ef4f0f36916b27a073 350 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 6 178 4.0E-66 T 28-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 A6A12_RS11240 5d0e17f778dfb4ef4f0f36916b27a073 350 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 153 170 - T 28-03-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 A6A12_RS11240 5d0e17f778dfb4ef4f0f36916b27a073 350 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 187 349 1.4E-65 T 28-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 A6A12_RS11240 5d0e17f778dfb4ef4f0f36916b27a073 350 SUPERFAMILY SSF54197 6 179 5.59E-72 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 A6A12_RS11240 5d0e17f778dfb4ef4f0f36916b27a073 350 PIRSF PIRSF000808 2 345 1.0E-123 T 28-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 A6A12_RS11240 5d0e17f778dfb4ef4f0f36916b27a073 350 Gene3D G3DSA:3.30.428.10 47 166 3.0E-48 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 A6A12_RS11240 5d0e17f778dfb4ef4f0f36916b27a073 350 SUPERFAMILY SSF54197 181 349 8.0E-54 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 A6A12_RS10935 0b627799bf0be8e39c473f73c46f5a5c 337 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 15 330 28.922 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A6A12_RS10935 0b627799bf0be8e39c473f73c46f5a5c 337 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 16 333 2.3E-103 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A6A12_RS10935 0b627799bf0be8e39c473f73c46f5a5c 337 SUPERFAMILY SSF56042 156 311 1.3E-32 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A6A12_RS10935 0b627799bf0be8e39c473f73c46f5a5c 337 PIRSF PIRSF005303 10 333 4.7E-84 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A6A12_RS10935 0b627799bf0be8e39c473f73c46f5a5c 337 Pfam PF00586 AIR synthase related protein, N-terminal domain 41 150 8.3E-21 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A6A12_RS10935 0b627799bf0be8e39c473f73c46f5a5c 337 Pfam PF02769 AIR synthase related protein, C-terminal domain 162 312 4.0E-10 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A6A12_RS10935 0b627799bf0be8e39c473f73c46f5a5c 337 Gene3D G3DSA:3.90.650.10 157 334 2.9E-38 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A6A12_RS10935 0b627799bf0be8e39c473f73c46f5a5c 337 SUPERFAMILY SSF55326 16 150 1.57E-32 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A6A12_RS10935 0b627799bf0be8e39c473f73c46f5a5c 337 Gene3D G3DSA:3.30.1330.10 10 154 5.8E-34 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A6A12_RS13900 5783dac96f9d374731f948b0abc65f89 460 Pfam PF04851 Type III restriction enzyme, res subunit 5 157 8.4E-9 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A6A12_RS13900 5783dac96f9d374731f948b0abc65f89 460 Gene3D G3DSA:3.40.50.300 2 166 3.7E-15 T 28-03-2018 A6A12_RS13900 5783dac96f9d374731f948b0abc65f89 460 SMART SM00487 1 182 9.6E-6 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS13900 5783dac96f9d374731f948b0abc65f89 460 SUPERFAMILY SSF52540 227 359 1.9E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13900 5783dac96f9d374731f948b0abc65f89 460 SUPERFAMILY SSF52540 24 160 1.9E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13900 5783dac96f9d374731f948b0abc65f89 460 Pfam PF00271 Helicase conserved C-terminal domain 258 356 1.5E-4 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS13900 5783dac96f9d374731f948b0abc65f89 460 Gene3D G3DSA:3.40.50.300 213 419 5.4E-8 T 28-03-2018 A6A12_RS13345 1c3ea9c276cc73de073919737128cd2a 209 SUPERFAMILY SSF55729 44 178 1.06E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS13345 1c3ea9c276cc73de073919737128cd2a 209 Gene3D G3DSA:3.40.630.30 30 193 4.8E-11 T 28-03-2018 A6A12_RS13345 1c3ea9c276cc73de073919737128cd2a 209 Pfam PF13420 Acetyltransferase (GNAT) domain 65 175 6.7E-9 T 28-03-2018 A6A12_RS00090 a835bb51a9ac8264444b9202d8bae968 613 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 607 3.4E-262 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A6A12_RS00090 a835bb51a9ac8264444b9202d8bae968 613 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A6A12_RS00090 a835bb51a9ac8264444b9202d8bae968 613 Pfam PF00920 Dehydratase family 34 604 9.0E-217 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A6A12_RS00090 a835bb51a9ac8264444b9202d8bae968 613 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 607 44.74 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A6A12_RS00090 a835bb51a9ac8264444b9202d8bae968 613 SUPERFAMILY SSF52016 421 608 5.41E-60 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A6A12_RS00090 a835bb51a9ac8264444b9202d8bae968 613 SUPERFAMILY SSF143975 3 420 2.62E-134 T 28-03-2018 A6A12_RS00090 a835bb51a9ac8264444b9202d8bae968 613 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 509 520 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A6A12_RS00270 1027ed6b26ecabeac03404a5180f5051 376 Pfam PF01476 LysM domain 39 85 7.9E-13 T 28-03-2018 IPR018392 LysM domain A6A12_RS00270 1027ed6b26ecabeac03404a5180f5051 376 SUPERFAMILY SSF54106 37 85 4.05E-7 T 28-03-2018 IPR018392 LysM domain A6A12_RS00270 1027ed6b26ecabeac03404a5180f5051 376 Gene3D G3DSA:3.10.350.10 32 87 3.3E-15 T 28-03-2018 A6A12_RS00270 1027ed6b26ecabeac03404a5180f5051 376 SMART SM00257 38 86 6.1E-5 T 28-03-2018 IPR018392 LysM domain A6A12_RS05425 f07c580538c057107dfec52d2022dde2 523 Pfam PF00425 chorismate binding enzyme 247 507 1.0E-84 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal A6A12_RS05425 f07c580538c057107dfec52d2022dde2 523 TIGRFAM TIGR00565 trpE_proteo: anthranilate synthase component I 22 519 5.1E-231 T 28-03-2018 IPR005257 Anthranilate synthase component I, TrpE-like, bacterial GO:0004049|GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A6A12_RS05425 f07c580538c057107dfec52d2022dde2 523 PRINTS PR00095 Anthranilate synthase component I signature 355 368 8.8E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A6A12_RS05425 f07c580538c057107dfec52d2022dde2 523 PRINTS PR00095 Anthranilate synthase component I signature 369 382 8.8E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A6A12_RS05425 f07c580538c057107dfec52d2022dde2 523 PRINTS PR00095 Anthranilate synthase component I signature 449 463 8.8E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A6A12_RS05425 f07c580538c057107dfec52d2022dde2 523 PRINTS PR00095 Anthranilate synthase component I signature 464 478 8.8E-23 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A6A12_RS05425 f07c580538c057107dfec52d2022dde2 523 Pfam PF04715 Anthranilate synthase component I, N terminal region 24 198 5.3E-14 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A6A12_RS05425 f07c580538c057107dfec52d2022dde2 523 PIRSF PIRSF001373 3 523 8.5E-261 T 28-03-2018 IPR005257 Anthranilate synthase component I, TrpE-like, bacterial GO:0004049|GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A6A12_RS05425 f07c580538c057107dfec52d2022dde2 523 SUPERFAMILY SSF56322 14 519 8.77E-160 T 28-03-2018 IPR005801 ADC synthase GO:0009058 A6A12_RS05425 f07c580538c057107dfec52d2022dde2 523 Gene3D G3DSA:3.60.120.10 6 523 8.7E-161 T 28-03-2018 IPR005801 ADC synthase GO:0009058 A6A12_RS13420 e2e026f148bcd247356c3545ce435c79 313 Gene3D G3DSA:3.40.50.720 1 168 2.5E-12 T 28-03-2018 A6A12_RS13420 e2e026f148bcd247356c3545ce435c79 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 241 4.1E-46 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A6A12_RS13420 e2e026f148bcd247356c3545ce435c79 313 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 313 45.883 T 28-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 A6A12_RS13420 e2e026f148bcd247356c3545ce435c79 313 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 312 1.2E-125 T 28-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 A6A12_RS13420 e2e026f148bcd247356c3545ce435c79 313 SUPERFAMILY SSF51735 1 308 4.34E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS13420 e2e026f148bcd247356c3545ce435c79 313 Gene3D G3DSA:3.90.25.10 169 313 1.4E-23 T 28-03-2018 A6A12_RS09050 e52872c14e92f3470233053088d46126 689 Pfam PF16458 Beta-prism lectin 317 451 1.9E-49 T 28-03-2018 IPR032496 Hemolysin, beta-prism lectin A6A12_RS09050 e52872c14e92f3470233053088d46126 689 SUPERFAMILY SSF69318 61 294 4.05E-20 T 28-03-2018 A6A12_RS09050 e52872c14e92f3470233053088d46126 689 ProSitePatterns PS00018 EF-hand calcium-binding domain. 63 75 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site A6A12_RS09050 e52872c14e92f3470233053088d46126 689 Gene3D G3DSA:2.130.10.130 459 672 6.3E-6 T 28-03-2018 A6A12_RS09050 e52872c14e92f3470233053088d46126 689 Gene3D G3DSA:2.130.10.130 22 203 2.0E-8 T 28-03-2018 A6A12_RS09050 e52872c14e92f3470233053088d46126 689 Gene3D G3DSA:2.130.10.130 204 390 0.054 T 28-03-2018 A6A12_RS09050 e52872c14e92f3470233053088d46126 689 SUPERFAMILY SSF69318 487 667 2.22E-11 T 28-03-2018 A6A12_RS09050 e52872c14e92f3470233053088d46126 689 SUPERFAMILY SSF69318 202 283 2.22E-11 T 28-03-2018 A6A12_RS04715 d1d2bfdee3ab15294fe219d563d1afaf 543 Gene3D G3DSA:3.40.50.980 198 352 1.0E-30 T 28-03-2018 A6A12_RS04715 d1d2bfdee3ab15294fe219d563d1afaf 543 TIGRFAM TIGR02275 DHB_AMP_lig: (2,3-dihydroxybenzoyl)adenylate synthase 9 538 1.6E-241 T 28-03-2018 IPR011963 2,3-dihydroxybenzoate-AMP ligase GO:0008668|GO:0019290 A6A12_RS04715 d1d2bfdee3ab15294fe219d563d1afaf 543 Gene3D G3DSA:3.40.50.980 30 197 1.0E-27 T 28-03-2018 A6A12_RS04715 d1d2bfdee3ab15294fe219d563d1afaf 543 SUPERFAMILY SSF56801 12 541 6.28E-130 T 28-03-2018 A6A12_RS04715 d1d2bfdee3ab15294fe219d563d1afaf 543 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 531 1.7E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A6A12_RS04715 d1d2bfdee3ab15294fe219d563d1afaf 543 Gene3D G3DSA:2.30.38.10 365 440 3.5E-17 T 28-03-2018 A6A12_RS04715 d1d2bfdee3ab15294fe219d563d1afaf 543 ProSitePatterns PS00455 Putative AMP-binding domain signature. 198 209 - T 28-03-2018 IPR020845 AMP-binding, conserved site A6A12_RS04715 d1d2bfdee3ab15294fe219d563d1afaf 543 Gene3D G3DSA:3.30.300.30 441 543 3.5E-25 T 28-03-2018 A6A12_RS04715 d1d2bfdee3ab15294fe219d563d1afaf 543 Pfam PF00501 AMP-binding enzyme 37 446 2.3E-76 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A6A12_RS06310 d9b0906c6e265e9fe8a3e18f45a1fd68 264 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 129 252 3.4E-20 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A6A12_RS06310 d9b0906c6e265e9fe8a3e18f45a1fd68 264 PIRSF PIRSF029195 1 258 4.9E-41 T 28-03-2018 IPR016910 Uncharacterised conserved protein UCP029195, PTS-EIIA 2 A6A12_RS06310 d9b0906c6e265e9fe8a3e18f45a1fd68 264 SUPERFAMILY SSF55804 128 251 3.66E-23 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A6A12_RS06310 d9b0906c6e265e9fe8a3e18f45a1fd68 264 SUPERFAMILY SSF55594 8 87 2.49E-6 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS06310 d9b0906c6e265e9fe8a3e18f45a1fd68 264 Gene3D G3DSA:3.30.1340.10 1 90 9.9E-4 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS06310 d9b0906c6e265e9fe8a3e18f45a1fd68 264 Gene3D G3DSA:3.40.930.10 123 254 1.2E-20 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 SUPERFAMILY SSF81665 300 336 1.27E-9 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 SUPERFAMILY SSF81665 433 528 1.27E-9 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 SUPERFAMILY SSF81665 781 799 1.27E-9 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 Gene3D G3DSA:3.30.70.100 107 197 1.1E-17 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 732 751 1.6E-28 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 657 668 1.6E-28 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 755 767 1.6E-28 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 382 396 1.6E-28 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 548 1.6E-28 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 679 689 1.6E-28 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 SUPERFAMILY SSF81653 335 432 2.75E-24 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 265 841 4.5E-181 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 304 810 7.2E-92 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 536 542 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 SUPERFAMILY SSF56784 532 552 3.04E-60 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 SUPERFAMILY SSF56784 590 838 3.04E-60 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 Gene3D G3DSA:3.40.50.1000 658 797 8.4E-45 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 Gene3D G3DSA:3.30.70.100 5 82 1.1E-5 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 ProSitePatterns PS01047 Heavy-metal-associated domain. 113 142 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 Pfam PF00702 haloacid dehalogenase-like hydrolase 530 746 1.1E-46 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 246 842 8.9E-180 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 Pfam PF00403 Heavy-metal-associated domain 113 171 7.2E-12 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 SUPERFAMILY SSF55008 104 177 1.09E-16 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 Gene3D G3DSA:3.40.1110.10 551 657 9.7E-24 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 Gene3D G3DSA:1.20.1110.10 275 550 1.7E-36 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 PRINTS PR00943 Copper-transporting ATPase signature 709 726 1.1E-13 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 PRINTS PR00943 Copper-transporting ATPase signature 250 269 1.1E-13 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 PRINTS PR00943 Copper-transporting ATPase signature 123 137 1.1E-13 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 PRINTS PR00943 Copper-transporting ATPase signature 322 340 1.1E-13 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 PRINTS PR00943 Copper-transporting ATPase signature 455 469 1.1E-13 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 PRINTS PR00943 Copper-transporting ATPase signature 517 532 1.1E-13 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 PRINTS PR00943 Copper-transporting ATPase signature 805 819 1.1E-13 T 28-03-2018 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 SUPERFAMILY SSF55008 7 73 1.03E-6 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A6A12_RS10715 d0cab7a12b255dc96d2d7f3077b1de77 850 Pfam PF00122 E1-E2 ATPase 333 513 3.3E-49 T 28-03-2018 A6A12_RS09375 36a79993075c3f26e86ba23ade1ca907 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 56 9.6E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS09375 36a79993075c3f26e86ba23ade1ca907 335 Gene3D G3DSA:1.10.10.10 1 24 1.5E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09375 36a79993075c3f26e86ba23ade1ca907 335 SUPERFAMILY SSF47413 9 67 2.17E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS09375 36a79993075c3f26e86ba23ade1ca907 335 Gene3D G3DSA:1.10.260.40 25 61 1.6E-15 T 28-03-2018 A6A12_RS09375 36a79993075c3f26e86ba23ade1ca907 335 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 68 312 1.3E-30 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain A6A12_RS09375 36a79993075c3f26e86ba23ade1ca907 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 12 30 - T 28-03-2018 A6A12_RS09375 36a79993075c3f26e86ba23ade1ca907 335 Gene3D G3DSA:3.40.50.2300 62 182 3.1E-26 T 28-03-2018 A6A12_RS09375 36a79993075c3f26e86ba23ade1ca907 335 SUPERFAMILY SSF53822 67 322 5.57E-58 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A6A12_RS09375 36a79993075c3f26e86ba23ade1ca907 335 SMART SM00354 9 79 2.5E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS09375 36a79993075c3f26e86ba23ade1ca907 335 Gene3D G3DSA:3.40.50.2300 183 318 1.1E-35 T 28-03-2018 A6A12_RS01605 cdb9e2fd3407301ef55e5604f6423203 574 Pfam PF00437 Type II/IV secretion system protein 191 453 4.4E-77 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A6A12_RS01605 cdb9e2fd3407301ef55e5604f6423203 574 Gene3D G3DSA:3.40.50.300 289 566 1.1E-57 T 28-03-2018 A6A12_RS01605 cdb9e2fd3407301ef55e5604f6423203 574 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 42 148 1.8E-21 T 28-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 A6A12_RS01605 cdb9e2fd3407301ef55e5604f6423203 574 SUPERFAMILY SSF160246 4 145 1.75E-38 T 28-03-2018 A6A12_RS01605 cdb9e2fd3407301ef55e5604f6423203 574 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 381 395 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A6A12_RS01605 cdb9e2fd3407301ef55e5604f6423203 574 SUPERFAMILY SSF52540 174 558 9.76E-92 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01605 cdb9e2fd3407301ef55e5604f6423203 574 Gene3D G3DSA:3.30.450.90 147 286 5.8E-44 T 28-03-2018 A6A12_RS01605 cdb9e2fd3407301ef55e5604f6423203 574 SMART SM00382 314 435 0.0088 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS09880 c352298741f2014d7080a8763d28062e 164 SUPERFAMILY SSF50341 14 158 1.2E-41 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS09880 c352298741f2014d7080a8763d28062e 164 Gene3D G3DSA:2.40.50.180 37 100 6.5E-22 T 28-03-2018 A6A12_RS09880 c352298741f2014d7080a8763d28062e 164 Gene3D G3DSA:2.40.50.180 135 162 0.091 T 28-03-2018 A6A12_RS09880 c352298741f2014d7080a8763d28062e 164 Pfam PF01584 CheW-like domain 20 155 5.0E-40 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS09880 c352298741f2014d7080a8763d28062e 164 SMART SM00260 16 153 3.3E-50 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS09880 c352298741f2014d7080a8763d28062e 164 Gene3D G3DSA:2.30.30.40 101 134 1.4E-17 T 28-03-2018 A6A12_RS05745 90cb39831bf699f4d79e6f16b8558258 105 Pfam PF09413 Putative prokaryotic signal transducing protein 1 64 9.4E-6 T 28-03-2018 IPR018551 Domain of unknown function DUF2007 A6A12_RS05745 90cb39831bf699f4d79e6f16b8558258 105 ProSitePatterns PS01358 Zinc finger RanBP2-type signature. 80 99 - T 28-03-2018 IPR001876 Zinc finger, RanBP2-type A6A12_RS05745 90cb39831bf699f4d79e6f16b8558258 105 Gene3D G3DSA:3.30.70.790 1 75 2.0E-12 T 28-03-2018 A6A12_RS00445 05d620ba7d3362832b6ef061bfdca3fd 156 Pfam PF00210 Ferritin-like domain 18 156 2.1E-26 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A6A12_RS00445 05d620ba7d3362832b6ef061bfdca3fd 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 62 78 4.2E-14 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A6A12_RS00445 05d620ba7d3362832b6ef061bfdca3fd 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 38 54 4.2E-14 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A6A12_RS00445 05d620ba7d3362832b6ef061bfdca3fd 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 133 151 4.2E-14 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A6A12_RS00445 05d620ba7d3362832b6ef061bfdca3fd 156 PIRSF PIRSF005900 1 156 3.0E-46 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 A6A12_RS00445 05d620ba7d3362832b6ef061bfdca3fd 156 SUPERFAMILY SSF47240 2 156 3.14E-44 T 28-03-2018 IPR009078 Ferritin-like superfamily A6A12_RS00445 05d620ba7d3362832b6ef061bfdca3fd 156 ProSitePatterns PS00819 Dps protein family signature 2. 64 78 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 A6A12_RS00445 05d620ba7d3362832b6ef061bfdca3fd 156 Gene3D G3DSA:1.20.1260.10 6 156 1.3E-41 T 28-03-2018 IPR012347 Ferritin-related A6A12_RS00445 05d620ba7d3362832b6ef061bfdca3fd 156 ProSitePatterns PS00818 Dps protein family signature 1. 38 54 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 A6A12_RS12850 33f4ccecc9b217abcf57251b02510699 112 Pfam PF11333 Protein of unknown function (DUF3135) 9 88 4.3E-34 T 28-03-2018 IPR021482 Protein of unknown function DUF3135 A6A12_RS11575 e81c9e450153241df5a033fea600a118 288 Gene3D G3DSA:3.40.1010.10 12 121 2.1E-43 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A6A12_RS11575 e81c9e450153241df5a033fea600a118 288 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 13 213 3.7E-30 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A6A12_RS11575 e81c9e450153241df5a033fea600a118 288 SUPERFAMILY SSF53790 12 232 3.01E-85 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A6A12_RS11575 e81c9e450153241df5a033fea600a118 288 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 91 102 - T 28-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS11575 e81c9e450153241df5a033fea600a118 288 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 14 284 2.0E-101 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS11575 e81c9e450153241df5a033fea600a118 288 PIRSF PIRSF005917 1 287 4.6E-107 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS11575 e81c9e450153241df5a033fea600a118 288 Gene3D G3DSA:3.30.950.10 122 237 1.4E-42 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A6A12_RS11575 e81c9e450153241df5a033fea600a118 288 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 13 234 38.293 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS03045 a0f9fbc04b25e1faf4a1f5902ffa8918 683 Gene3D G3DSA:3.20.20.450 406 673 9.7E-96 T 28-03-2018 IPR001633 EAL domain A6A12_RS03045 a0f9fbc04b25e1faf4a1f5902ffa8918 683 Gene3D G3DSA:3.30.70.270 235 405 1.0E-57 T 28-03-2018 A6A12_RS03045 a0f9fbc04b25e1faf4a1f5902ffa8918 683 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 238 400 1.9E-39 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS03045 a0f9fbc04b25e1faf4a1f5902ffa8918 683 SMART SM00052 412 660 1.2E-102 T 28-03-2018 IPR001633 EAL domain A6A12_RS03045 a0f9fbc04b25e1faf4a1f5902ffa8918 683 SUPERFAMILY SSF55073 247 404 5.65E-49 T 28-03-2018 IPR029787 Nucleotide cyclase A6A12_RS03045 a0f9fbc04b25e1faf4a1f5902ffa8918 683 SUPERFAMILY SSF141868 418 667 1.31E-86 T 28-03-2018 IPR001633 EAL domain A6A12_RS03045 a0f9fbc04b25e1faf4a1f5902ffa8918 683 Pfam PF00563 EAL domain 420 655 4.1E-72 T 28-03-2018 IPR001633 EAL domain A6A12_RS03045 a0f9fbc04b25e1faf4a1f5902ffa8918 683 Pfam PF00990 Diguanylate cyclase, GGDEF domain 242 398 2.4E-45 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS03045 a0f9fbc04b25e1faf4a1f5902ffa8918 683 SMART SM00267 231 402 5.1E-61 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS06605 d431daa3e7151d28dc45bc74bd9da921 868 Gene3D G3DSA:2.60.40.1730 15 193 2.7E-31 T 28-03-2018 A6A12_RS06605 d431daa3e7151d28dc45bc74bd9da921 868 SUPERFAMILY SSF63737 3 192 2.88E-46 T 28-03-2018 A6A12_RS06605 d431daa3e7151d28dc45bc74bd9da921 868 SUPERFAMILY SSF55486 203 449 9.16E-75 T 28-03-2018 A6A12_RS06605 d431daa3e7151d28dc45bc74bd9da921 868 Gene3D G3DSA:1.25.50.10 545 867 9.4E-118 T 28-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal A6A12_RS06605 d431daa3e7151d28dc45bc74bd9da921 868 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 312 324 4.3E-9 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A6A12_RS06605 d431daa3e7151d28dc45bc74bd9da921 868 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 175 190 4.3E-9 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A6A12_RS06605 d431daa3e7151d28dc45bc74bd9da921 868 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 293 308 4.3E-9 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A6A12_RS06605 d431daa3e7151d28dc45bc74bd9da921 868 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 257 267 4.3E-9 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A6A12_RS06605 d431daa3e7151d28dc45bc74bd9da921 868 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 125 140 4.3E-9 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A6A12_RS06605 d431daa3e7151d28dc45bc74bd9da921 868 Gene3D G3DSA:1.10.390.10 279 442 1.3E-49 T 28-03-2018 A6A12_RS06605 d431daa3e7151d28dc45bc74bd9da921 868 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 12 866 0.0 T 28-03-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 A6A12_RS06605 d431daa3e7151d28dc45bc74bd9da921 868 Pfam PF01433 Peptidase family M1 domain 207 435 6.2E-58 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A6A12_RS06605 d431daa3e7151d28dc45bc74bd9da921 868 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 443 544 1.1E-33 T 28-03-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold A6A12_RS06605 d431daa3e7151d28dc45bc74bd9da921 868 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 547 867 1.6E-114 T 28-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal A6A12_RS12030 b4e6d5ceb92c045d22e47459942b1a58 320 Gene3D G3DSA:3.40.50.720 116 290 2.4E-51 T 28-03-2018 A6A12_RS12030 b4e6d5ceb92c045d22e47459942b1a58 320 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 35 318 1.7E-22 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A6A12_RS12030 b4e6d5ceb92c045d22e47459942b1a58 320 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 196 218 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A6A12_RS12030 b4e6d5ceb92c045d22e47459942b1a58 320 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 225 241 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A6A12_RS12030 b4e6d5ceb92c045d22e47459942b1a58 320 SUPERFAMILY SSF52283 4 139 5.48E-31 T 28-03-2018 A6A12_RS12030 b4e6d5ceb92c045d22e47459942b1a58 320 Gene3D G3DSA:3.40.50.720 6 115 2.9E-26 T 28-03-2018 A6A12_RS12030 b4e6d5ceb92c045d22e47459942b1a58 320 SUPERFAMILY SSF51735 103 290 4.88E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS12030 b4e6d5ceb92c045d22e47459942b1a58 320 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 289 3.6E-55 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A6A12_RS11825 2b4b4aedf26dc198a60332f9aa78dfce 207 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 1 96 2.0E-34 T 28-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 A6A12_RS11825 2b4b4aedf26dc198a60332f9aa78dfce 207 SUPERFAMILY SSF89069 4 67 4.71E-20 T 28-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 A6A12_RS11825 2b4b4aedf26dc198a60332f9aa78dfce 207 PIRSF PIRSF016938 1 202 3.7E-36 T 28-03-2018 IPR026279 Sigma-E factor negative regulatory protein RseA GO:0006950|GO:0016989 A6A12_RS11825 2b4b4aedf26dc198a60332f9aa78dfce 207 Pfam PF03873 Anti sigma-E protein RseA, C-terminal domain 138 190 1.8E-19 T 28-03-2018 IPR005573 Anti sigma-E protein RseA, C-terminal A6A12_RS10750 06fa872aedbc3977e55e06747686b838 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 178 337 1.6E-38 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A6A12_RS10750 06fa872aedbc3977e55e06747686b838 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 8 345 47.608 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A6A12_RS10750 06fa872aedbc3977e55e06747686b838 346 Gene3D G3DSA:3.90.650.10 172 346 9.6E-65 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A6A12_RS10750 06fa872aedbc3977e55e06747686b838 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 57 165 6.7E-16 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A6A12_RS10750 06fa872aedbc3977e55e06747686b838 346 SUPERFAMILY SSF56042 172 336 3.89E-61 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain A6A12_RS10750 06fa872aedbc3977e55e06747686b838 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 8 335 1.3E-150 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A6A12_RS10750 06fa872aedbc3977e55e06747686b838 346 SUPERFAMILY SSF55326 8 171 1.15E-54 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A6A12_RS10750 06fa872aedbc3977e55e06747686b838 346 Gene3D G3DSA:3.30.1330.10 36 162 5.5E-54 T 28-03-2018 IPR016188 PurM-like, N-terminal domain A6A12_RS06080 011aeb2c03542d946a879dcda1744d27 580 Pfam PF00271 Helicase conserved C-terminal domain 239 342 6.6E-15 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS06080 011aeb2c03542d946a879dcda1744d27 580 Pfam PF04851 Type III restriction enzyme, res subunit 2 154 2.5E-23 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A6A12_RS06080 011aeb2c03542d946a879dcda1744d27 580 SMART SM00490 261 344 1.1E-10 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS06080 011aeb2c03542d946a879dcda1744d27 580 SMART SM00487 1 184 1.7E-13 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS06080 011aeb2c03542d946a879dcda1744d27 580 Gene3D G3DSA:3.40.50.300 220 359 4.2E-21 T 28-03-2018 A6A12_RS06080 011aeb2c03542d946a879dcda1744d27 580 SUPERFAMILY SSF57829 424 465 2.2E-6 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A6A12_RS06080 011aeb2c03542d946a879dcda1744d27 580 SUPERFAMILY SSF52540 48 188 4.88E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS06080 011aeb2c03542d946a879dcda1744d27 580 SUPERFAMILY SSF52540 236 362 4.88E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS06080 011aeb2c03542d946a879dcda1744d27 580 Gene3D G3DSA:3.40.50.300 1 170 1.8E-27 T 28-03-2018 A6A12_RS10065 f869020b1ba7e4520556a26523c9c355 73 Pfam PF10981 Protein of unknown function (DUF2788) 18 67 3.2E-18 T 28-03-2018 IPR021249 Protein of unknown function DUF2788 A6A12_RS11940 b04662899421cbe90ce8b5c992067652 363 SMART SM01329 7 356 3.5E-201 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A6A12_RS11940 b04662899421cbe90ce8b5c992067652 363 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 248 267 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 A6A12_RS11940 b04662899421cbe90ce8b5c992067652 363 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 7 356 1.2E-164 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 A6A12_RS11940 b04662899421cbe90ce8b5c992067652 363 Gene3D G3DSA:3.40.718.10 1 363 1.9E-131 T 28-03-2018 A6A12_RS11940 b04662899421cbe90ce8b5c992067652 363 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 356 7.3E-136 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 A6A12_RS11940 b04662899421cbe90ce8b5c992067652 363 SUPERFAMILY SSF53659 4 360 1.24E-122 T 28-03-2018 A6A12_RS11940 b04662899421cbe90ce8b5c992067652 363 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 6 360 51.248 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 A6A12_RS00440 afff773adeb5c44713f7031504fc05a4 408 SUPERFAMILY SSF141868 5 199 3.27E-26 T 28-03-2018 IPR001633 EAL domain A6A12_RS00440 afff773adeb5c44713f7031504fc05a4 408 SUPERFAMILY SSF109604 185 404 4.08E-41 T 28-03-2018 A6A12_RS00440 afff773adeb5c44713f7031504fc05a4 408 Pfam PF00563 EAL domain 77 194 1.8E-11 T 28-03-2018 IPR001633 EAL domain A6A12_RS00440 afff773adeb5c44713f7031504fc05a4 408 PIRSF PIRSF003180 1 408 2.1E-165 T 28-03-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing A6A12_RS00440 afff773adeb5c44713f7031504fc05a4 408 Gene3D G3DSA:1.10.3210.10 199 396 5.0E-17 T 28-03-2018 A6A12_RS00440 afff773adeb5c44713f7031504fc05a4 408 SMART SM00052 2 199 0.0078 T 28-03-2018 IPR001633 EAL domain A6A12_RS00440 afff773adeb5c44713f7031504fc05a4 408 Gene3D G3DSA:3.20.20.450 4 198 4.2E-19 T 28-03-2018 IPR001633 EAL domain A6A12_RS00440 afff773adeb5c44713f7031504fc05a4 408 Pfam PF08668 HDOD domain 208 324 5.4E-13 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD A6A12_RS06345 6e643c5b27168244d7bc69d0dfaff3c4 502 SUPERFAMILY SSF52540 246 488 3.58E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS06345 6e643c5b27168244d7bc69d0dfaff3c4 502 Gene3D G3DSA:3.40.50.300 6 236 1.1E-47 T 28-03-2018 A6A12_RS06345 6e643c5b27168244d7bc69d0dfaff3c4 502 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS06345 6e643c5b27168244d7bc69d0dfaff3c4 502 SUPERFAMILY SSF52540 8 229 5.84E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS06345 6e643c5b27168244d7bc69d0dfaff3c4 502 Gene3D G3DSA:3.40.50.300 245 500 2.7E-32 T 28-03-2018 A6A12_RS06345 6e643c5b27168244d7bc69d0dfaff3c4 502 Pfam PF00005 ABC transporter 25 174 6.8E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS06345 6e643c5b27168244d7bc69d0dfaff3c4 502 Pfam PF00005 ABC transporter 276 430 3.6E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS06345 6e643c5b27168244d7bc69d0dfaff3c4 502 SMART SM00382 34 221 6.7E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS06345 6e643c5b27168244d7bc69d0dfaff3c4 502 SMART SM00382 284 479 2.0 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS08035 bfb224fc73fc6e75ce8096dc116aa1b6 342 Gene3D G3DSA:3.40.50.10210 66 323 1.3E-95 T 28-03-2018 A6A12_RS08035 bfb224fc73fc6e75ce8096dc116aa1b6 342 Pfam PF02277 Phosphoribosyltransferase 3 340 3.9E-126 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A6A12_RS08035 bfb224fc73fc6e75ce8096dc116aa1b6 342 Gene3D G3DSA:1.10.1610.10 1 65 1.2E-28 T 28-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A6A12_RS08035 bfb224fc73fc6e75ce8096dc116aa1b6 342 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 1 342 35.542 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A6A12_RS08035 bfb224fc73fc6e75ce8096dc116aa1b6 342 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 4 340 7.1E-129 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A6A12_RS08035 bfb224fc73fc6e75ce8096dc116aa1b6 342 SUPERFAMILY SSF52733 3 341 2.35E-109 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A6A12_RS00015 6fbb7dfcb6337617e7069329dcebe1d0 359 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 359 97.047 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A6A12_RS00015 6fbb7dfcb6337617e7069329dcebe1d0 359 ProSitePatterns PS00617 RecF protein signature 1. 118 138 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 A6A12_RS00015 6fbb7dfcb6337617e7069329dcebe1d0 359 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 356 2.8E-117 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 A6A12_RS00015 6fbb7dfcb6337617e7069329dcebe1d0 359 ProSitePatterns PS00618 RecF protein signature 2. 299 317 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 A6A12_RS00015 6fbb7dfcb6337617e7069329dcebe1d0 359 Gene3D G3DSA:3.40.50.300 1 359 1.6E-30 T 28-03-2018 A6A12_RS00015 6fbb7dfcb6337617e7069329dcebe1d0 359 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 356 6.8E-37 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal A6A12_RS00015 6fbb7dfcb6337617e7069329dcebe1d0 359 SUPERFAMILY SSF52540 1 341 2.45E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12385 c8acb1178e9cf68321a7d92fbcd2fd00 206 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 95 1.6E-32 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A6A12_RS12385 c8acb1178e9cf68321a7d92fbcd2fd00 206 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 206 36.126 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A6A12_RS12385 c8acb1178e9cf68321a7d92fbcd2fd00 206 ProSitePatterns PS00632 Ribosomal protein S4 signature. 94 118 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12385 c8acb1178e9cf68321a7d92fbcd2fd00 206 Pfam PF01479 S4 domain 97 143 4.3E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS12385 c8acb1178e9cf68321a7d92fbcd2fd00 206 Gene3D G3DSA:1.10.1050.10 146 206 6.9E-18 T 28-03-2018 A6A12_RS12385 c8acb1178e9cf68321a7d92fbcd2fd00 206 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 206 4.5E-84 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 A6A12_RS12385 c8acb1178e9cf68321a7d92fbcd2fd00 206 Gene3D G3DSA:3.10.290.10 102 145 1.3E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS12385 c8acb1178e9cf68321a7d92fbcd2fd00 206 SMART SM00363 96 160 2.3E-19 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS12385 c8acb1178e9cf68321a7d92fbcd2fd00 206 Gene3D G3DSA:1.10.1050.10 1 101 1.7E-41 T 28-03-2018 A6A12_RS12385 c8acb1178e9cf68321a7d92fbcd2fd00 206 SUPERFAMILY SSF55174 3 206 6.41E-72 T 28-03-2018 A6A12_RS12385 c8acb1178e9cf68321a7d92fbcd2fd00 206 SMART SM01390 3 95 1.0E-49 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A6A12_RS06260 dd7f41dcc357783d47d295d14e22fa15 296 PIRSF PIRSF015582 2 296 1.8E-74 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like A6A12_RS06260 dd7f41dcc357783d47d295d14e22fa15 296 TIGRFAM TIGR01588 citE: citrate (pro-3S)-lyase, beta subunit 8 291 3.1E-136 T 28-03-2018 IPR006475 Citrate lyase, beta subunit, bacteria GO:0005737|GO:0006084|GO:0008816|GO:0009346 KEGG: 00720+4.1.3.34|MetaCyc: PWY-5392|MetaCyc: PWY-6038 A6A12_RS06260 dd7f41dcc357783d47d295d14e22fa15 296 SUPERFAMILY SSF51621 7 240 9.07E-61 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A6A12_RS06260 dd7f41dcc357783d47d295d14e22fa15 296 Gene3D G3DSA:3.20.20.360 4 267 7.6E-47 T 28-03-2018 A6A12_RS06260 dd7f41dcc357783d47d295d14e22fa15 296 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 11 230 5.4E-79 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 A6A12_RS14325 bb649ef7dce23803277b8b23180d08b9 391 SUPERFAMILY SSF53901 266 390 2.64E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS14325 bb649ef7dce23803277b8b23180d08b9 391 PIRSF PIRSF000429 2 391 2.3E-134 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A6A12_RS14325 bb649ef7dce23803277b8b23180d08b9 391 Gene3D G3DSA:3.40.47.10 261 388 1.7E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS14325 bb649ef7dce23803277b8b23180d08b9 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 389 1.5E-143 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 A6A12_RS14325 bb649ef7dce23803277b8b23180d08b9 391 TIGRFAM TIGR02445 fadA: acetyl-CoA C-acyltransferase FadA 7 391 1.4E-236 T 28-03-2018 IPR012805 Acetyl-CoA C-acyltransferase FadA GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 A6A12_RS14325 bb649ef7dce23803277b8b23180d08b9 391 SUPERFAMILY SSF53901 5 262 1.15E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS14325 bb649ef7dce23803277b8b23180d08b9 391 Pfam PF00108 Thiolase, N-terminal domain 8 258 1.2E-84 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 A6A12_RS14325 bb649ef7dce23803277b8b23180d08b9 391 Pfam PF02803 Thiolase, C-terminal domain 266 390 1.2E-49 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 A6A12_RS14325 bb649ef7dce23803277b8b23180d08b9 391 Gene3D G3DSA:3.40.47.10 134 260 1.5E-24 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS14325 bb649ef7dce23803277b8b23180d08b9 391 Gene3D G3DSA:3.40.47.10 1 133 3.7E-26 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS14325 bb649ef7dce23803277b8b23180d08b9 391 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 A6A12_RS14325 bb649ef7dce23803277b8b23180d08b9 391 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 A6A12_RS14325 bb649ef7dce23803277b8b23180d08b9 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 91 109 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 A6A12_RS14325 bb649ef7dce23803277b8b23180d08b9 391 Hamap MF_01620 3-ketoacyl-CoA thiolase [fadA]. 5 391 60.133 T 28-03-2018 IPR012805 Acetyl-CoA C-acyltransferase FadA GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 A6A12_RS06905 08a580c193a60a6f4de3f0036c1c0826 394 Gene3D G3DSA:1.25.40.10 325 393 2.0E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS06905 08a580c193a60a6f4de3f0036c1c0826 394 Gene3D G3DSA:1.25.40.10 154 273 7.7E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS06905 08a580c193a60a6f4de3f0036c1c0826 394 SUPERFAMILY SSF48452 60 170 1.9E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS06905 08a580c193a60a6f4de3f0036c1c0826 394 Gene3D G3DSA:1.25.40.10 18 153 2.8E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS06905 08a580c193a60a6f4de3f0036c1c0826 394 Pfam PF13181 Tetratricopeptide repeat 306 336 0.016 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS06905 08a580c193a60a6f4de3f0036c1c0826 394 Gene3D G3DSA:1.25.40.10 274 324 9.4E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS06905 08a580c193a60a6f4de3f0036c1c0826 394 SUPERFAMILY SSF48452 138 334 5.91E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS11360 95466bdefe7deb7b74d02488a01e9c2a 125 Hamap MF_00806 Autonomous glycyl radical cofactor [grcA]. 1 125 41.06 T 28-03-2018 IPR011140 Autonomous glycyl radical cofactor GrcA A6A12_RS11360 95466bdefe7deb7b74d02488a01e9c2a 125 Gene3D G3DSA:3.20.70.20 14 125 1.2E-29 T 28-03-2018 A6A12_RS11360 95466bdefe7deb7b74d02488a01e9c2a 125 TIGRFAM TIGR04365 spare_glycyl: autonomous glycyl radical cofactor GrcA 2 125 1.5E-68 T 28-03-2018 IPR011140 Autonomous glycyl radical cofactor GrcA A6A12_RS11360 95466bdefe7deb7b74d02488a01e9c2a 125 ProSitePatterns PS00850 Glycine radical domain signature. 95 103 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site A6A12_RS11360 95466bdefe7deb7b74d02488a01e9c2a 125 PIRSF PIRSF000378 2 125 5.1E-54 T 28-03-2018 IPR011140 Autonomous glycyl radical cofactor GrcA A6A12_RS11360 95466bdefe7deb7b74d02488a01e9c2a 125 SUPERFAMILY SSF51998 63 124 1.24E-23 T 28-03-2018 A6A12_RS11360 95466bdefe7deb7b74d02488a01e9c2a 125 Pfam PF01228 Glycine radical 15 106 1.6E-23 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 A6A12_RS09010 41725c09c133ba14589c5e6ce5839743 747 SUPERFAMILY SSF56281 489 730 2.98E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS09010 41725c09c133ba14589c5e6ce5839743 747 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 230 402 2.7E-28 T 28-03-2018 IPR004477 ComEC/Rec2-related protein A6A12_RS09010 41725c09c133ba14589c5e6ce5839743 747 Pfam PF13567 Domain of unknown function (DUF4131) 24 172 8.7E-9 T 28-03-2018 IPR025405 Domain of unknown function DUF4131 A6A12_RS09010 41725c09c133ba14589c5e6ce5839743 747 SMART SM00849 501 684 2.3E-4 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS09010 41725c09c133ba14589c5e6ce5839743 747 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 136 713 1.1E-120 T 28-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 A6A12_RS09010 41725c09c133ba14589c5e6ce5839743 747 Pfam PF00753 Metallo-beta-lactamase superfamily 499 680 9.1E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS09010 41725c09c133ba14589c5e6ce5839743 747 Gene3D G3DSA:3.60.15.10 489 711 5.8E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS09010 41725c09c133ba14589c5e6ce5839743 747 Pfam PF03772 Competence protein 208 462 4.4E-54 T 28-03-2018 IPR004477 ComEC/Rec2-related protein A6A12_RS13305 1fd17199122a16cc3effa962e3da4a01 362 Gene3D G3DSA:3.90.550.10 9 235 6.5E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13305 1fd17199122a16cc3effa962e3da4a01 362 SUPERFAMILY SSF53448 9 232 7.97E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13305 1fd17199122a16cc3effa962e3da4a01 362 Pfam PF00535 Glycosyl transferase family 2 12 168 2.5E-21 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A6A12_RS13105 94450c15c4061f14b45db0c88adfe823 295 Gene3D G3DSA:3.40.50.150 102 295 7.7E-34 T 28-03-2018 A6A12_RS13105 94450c15c4061f14b45db0c88adfe823 295 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 287 8.8E-106 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A6A12_RS13105 94450c15c4061f14b45db0c88adfe823 295 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 293 6.7E-102 T 28-03-2018 A6A12_RS13105 94450c15c4061f14b45db0c88adfe823 295 SUPERFAMILY SSF53335 45 291 1.79E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS13105 94450c15c4061f14b45db0c88adfe823 295 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 293 32.747 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A6A12_RS13105 94450c15c4061f14b45db0c88adfe823 295 PIRSF PIRSF000401 1 295 6.9E-96 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 A6A12_RS11810 1831584882c847f941740c0056d0e464 597 Pfam PF00679 Elongation factor G C-terminus 399 481 2.3E-18 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like A6A12_RS11810 1831584882c847f941740c0056d0e464 597 Hamap MF_00071 Elongation factor 4 [lepA]. 1 597 305.653 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 A6A12_RS11810 1831584882c847f941740c0056d0e464 597 Pfam PF00009 Elongation factor Tu GTP binding domain 2 181 4.4E-53 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS11810 1831584882c847f941740c0056d0e464 597 Pfam PF03144 Elongation factor Tu domain 2 205 275 6.3E-9 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A6A12_RS11810 1831584882c847f941740c0056d0e464 597 Gene3D G3DSA:3.40.50.300 1 185 3.2E-37 T 28-03-2018 A6A12_RS11810 1831584882c847f941740c0056d0e464 597 Gene3D G3DSA:2.40.30.10 188 287 1.3E-22 T 28-03-2018 A6A12_RS11810 1831584882c847f941740c0056d0e464 597 Pfam PF06421 GTP-binding protein LepA C-terminus 487 592 2.2E-49 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal A6A12_RS11810 1831584882c847f941740c0056d0e464 597 Gene3D G3DSA:3.30.70.240 390 549 1.0E-25 T 28-03-2018 A6A12_RS11810 1831584882c847f941740c0056d0e464 597 TIGRFAM TIGR01393 lepA: elongation factor 4 2 594 5.4E-302 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 A6A12_RS11810 1831584882c847f941740c0056d0e464 597 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site A6A12_RS11810 1831584882c847f941740c0056d0e464 597 SUPERFAMILY SSF52540 2 232 1.1E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11810 1831584882c847f941740c0056d0e464 597 SUPERFAMILY SSF54980 399 493 1.44E-23 T 28-03-2018 IPR035647 EF-G domain III/V-like A6A12_RS11810 1831584882c847f941740c0056d0e464 597 Gene3D G3DSA:3.30.70.870 288 367 1.9E-27 T 28-03-2018 A6A12_RS11810 1831584882c847f941740c0056d0e464 597 PRINTS PR00315 GTP-binding elongation factor signature 6 19 3.8E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS11810 1831584882c847f941740c0056d0e464 597 PRINTS PR00315 GTP-binding elongation factor signature 90 101 3.8E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS11810 1831584882c847f941740c0056d0e464 597 PRINTS PR00315 GTP-binding elongation factor signature 126 135 3.8E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS11810 1831584882c847f941740c0056d0e464 597 PRINTS PR00315 GTP-binding elongation factor signature 74 84 3.8E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS11810 1831584882c847f941740c0056d0e464 597 PRINTS PR00315 GTP-binding elongation factor signature 49 57 3.8E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS11810 1831584882c847f941740c0056d0e464 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 176 9.3E-17 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A6A12_RS11810 1831584882c847f941740c0056d0e464 597 SUPERFAMILY SSF54980 292 370 1.62E-18 T 28-03-2018 IPR035647 EF-G domain III/V-like A6A12_RS01700 fa76f7aa13445424d051ac518323669d 141 SUPERFAMILY SSF89946 9 127 6.02E-38 T 28-03-2018 IPR009671 Regulator of ribonuclease activity B domain A6A12_RS01700 fa76f7aa13445424d051ac518323669d 141 PIRSF PIRSF018193 10 141 6.5E-58 T 28-03-2018 IPR016716 Regulator of ribonuclease activity B A6A12_RS01700 fa76f7aa13445424d051ac518323669d 141 Gene3D G3DSA:3.30.70.970 12 125 1.4E-43 T 28-03-2018 IPR009671 Regulator of ribonuclease activity B domain A6A12_RS01700 fa76f7aa13445424d051ac518323669d 141 Hamap MF_01888 Regulator of ribonuclease activity B [rraB]. 13 126 28.867 T 28-03-2018 IPR016716 Regulator of ribonuclease activity B A6A12_RS01700 fa76f7aa13445424d051ac518323669d 141 Pfam PF06877 Regulator of ribonuclease activity B 21 122 4.4E-33 T 28-03-2018 IPR009671 Regulator of ribonuclease activity B domain A6A12_RS05400 d49eac9cd6672f88e144d847698d016a 268 SUPERFAMILY SSF51366 1 266 2.83E-93 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A6A12_RS05400 d49eac9cd6672f88e144d847698d016a 268 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 263 4.8E-104 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A6A12_RS05400 d49eac9cd6672f88e144d847698d016a 268 Pfam PF00290 Tryptophan synthase alpha chain 8 266 5.7E-99 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A6A12_RS05400 d49eac9cd6672f88e144d847698d016a 268 Gene3D G3DSA:3.20.20.70 2 268 2.0E-74 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS05400 d49eac9cd6672f88e144d847698d016a 268 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 265 38.797 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A6A12_RS05400 d49eac9cd6672f88e144d847698d016a 268 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A6A12_RS14360 1938f8fa9c5f8d0df07de95d43fffab1 513 Gene3D G3DSA:2.40.30.20 3 82 4.1E-28 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14360 1938f8fa9c5f8d0df07de95d43fffab1 513 SUPERFAMILY SSF50615 10 94 1.37E-25 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A6A12_RS14360 1938f8fa9c5f8d0df07de95d43fffab1 513 SUPERFAMILY SSF52540 96 381 3.13E-94 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS14360 1938f8fa9c5f8d0df07de95d43fffab1 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 92 1.3E-13 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A6A12_RS14360 1938f8fa9c5f8d0df07de95d43fffab1 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 49.812 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14360 1938f8fa9c5f8d0df07de95d43fffab1 513 Gene3D G3DSA:1.20.150.20 384 510 8.3E-45 T 28-03-2018 A6A12_RS14360 1938f8fa9c5f8d0df07de95d43fffab1 513 SUPERFAMILY SSF47917 383 511 7.59E-46 T 28-03-2018 A6A12_RS14360 1938f8fa9c5f8d0df07de95d43fffab1 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A6A12_RS14360 1938f8fa9c5f8d0df07de95d43fffab1 513 Gene3D G3DSA:3.40.50.300 83 375 2.1E-111 T 28-03-2018 A6A12_RS14360 1938f8fa9c5f8d0df07de95d43fffab1 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 7.7E-72 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A6A12_RS14360 1938f8fa9c5f8d0df07de95d43fffab1 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 2 512 1.3E-251 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14360 1938f8fa9c5f8d0df07de95d43fffab1 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 3.9E-44 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 Gene3D G3DSA:1.10.287.380 879 949 3.9E-26 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 PRINTS PR00986 Valyl-tRNA synthetase signature 369 382 7.0E-34 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 PRINTS PR00986 Valyl-tRNA synthetase signature 469 490 7.0E-34 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 7.0E-34 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 PRINTS PR00986 Valyl-tRNA synthetase signature 500 518 7.0E-34 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 PRINTS PR00986 Valyl-tRNA synthetase signature 35 46 7.0E-34 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 886 946 5.0E-18 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 SUPERFAMILY SSF47323 642 900 1.2E-68 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 Gene3D G3DSA:1.10.730.10 631 818 5.7E-50 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 Hamap MF_02004 Valine--tRNA ligase [valS]. 1 951 15.965 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 SUPERFAMILY SSF46589 886 950 6.8E-17 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 Pfam PF08264 Anticodon-binding domain of tRNA 675 827 3.0E-40 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 SUPERFAMILY SSF52374 364 571 6.66E-135 T 28-03-2018 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 SUPERFAMILY SSF52374 1 192 6.66E-135 T 28-03-2018 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 SUPERFAMILY SSF52374 609 641 6.66E-135 T 28-03-2018 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 TIGRFAM TIGR00422 valS: valine--tRNA ligase 1 933 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 631 3.3E-224 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 SUPERFAMILY SSF50677 191 364 1.7E-57 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A6A12_RS12025 5088426ddaf8ad4d80045dfaa80be78e 953 Gene3D G3DSA:3.40.50.620 2 630 2.4E-134 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 8 305 1.3E-116 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 1.5E-44 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 Gene3D G3DSA:3.40.50.1370 1 146 7.1E-50 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 SUPERFAMILY SSF53671 4 306 1.7E-101 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 1.8E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 1.8E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 1.8E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 1.8E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 7 307 38.741 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 303 6.5E-33 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 Gene3D G3DSA:3.40.50.1370 147 292 5.3E-50 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 226 235 2.8E-37 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 79 88 2.8E-37 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 2.8E-37 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 2.8E-37 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 2.8E-37 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS13025 138767a9e44a1baa04e8bb3c2597ec46 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 2.8E-37 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS13170 44bf36f229d3964a03bc24ebaae7f442 411 Gene3D G3DSA:3.30.70.100 308 399 0.0026 T 28-03-2018 A6A12_RS13170 44bf36f229d3964a03bc24ebaae7f442 411 SUPERFAMILY SSF50182 186 251 5.23E-11 T 28-03-2018 IPR010920 LSM domain A6A12_RS13170 44bf36f229d3964a03bc24ebaae7f442 411 Gene3D G3DSA:2.30.30.60 201 251 9.7E-10 T 28-03-2018 A6A12_RS13170 44bf36f229d3964a03bc24ebaae7f442 411 Pfam PF00924 Mechanosensitive ion channel 143 396 5.9E-50 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A6A12_RS09285 880a011ae386bec5451a90418b812836 122 SUPERFAMILY SSF54637 17 94 4.32E-12 T 28-03-2018 IPR029069 HotDog domain A6A12_RS09285 880a011ae386bec5451a90418b812836 122 Gene3D G3DSA:3.10.129.10 10 120 1.3E-17 T 28-03-2018 A6A12_RS09285 880a011ae386bec5451a90418b812836 122 PIRSF PIRSF030962 1 121 4.3E-49 T 28-03-2018 IPR016962 Dehydrase, ECs4332, predicted KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A6A12_RS04785 f50eaae270b405f1b576cf46d2b2b953 157 Pfam PF02391 MoaE protein 11 120 7.8E-38 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A6A12_RS04785 f50eaae270b405f1b576cf46d2b2b953 157 Gene3D G3DSA:3.90.1170.40 2 151 9.4E-58 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A6A12_RS04785 f50eaae270b405f1b576cf46d2b2b953 157 SUPERFAMILY SSF54690 5 150 1.7E-55 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A6A12_RS02245 6e5551b4e2c864e7cc8927568cbbaec5 112 Gene3D G3DSA:3.20.140.10 1 110 3.4E-5 T 28-03-2018 A6A12_RS02245 6e5551b4e2c864e7cc8927568cbbaec5 112 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 15 103 1.2E-17 T 28-03-2018 IPR009241 Toxin HigB-like A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 5.6E-35 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 SMART SM00838 605 693 1.9E-59 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 Pfam PF14492 Elongation Factor G, domain II 409 483 1.3E-33 T 28-03-2018 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 SMART SM00889 485 603 1.9E-76 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 4.0E-67 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 SUPERFAMILY SSF52540 6 288 1.12E-107 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 Gene3D G3DSA:3.40.50.300 1 293 2.5E-62 T 28-03-2018 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 Pfam PF03764 Elongation factor G, domain IV 484 603 5.3E-49 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 PRINTS PR00315 GTP-binding elongation factor signature 101 112 9.4E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 PRINTS PR00315 GTP-binding elongation factor signature 12 25 9.4E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 PRINTS PR00315 GTP-binding elongation factor signature 85 95 9.4E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 PRINTS PR00315 GTP-binding elongation factor signature 137 146 9.4E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 PRINTS PR00315 GTP-binding elongation factor signature 58 66 9.4E-17 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 SUPERFAMILY SSF54980 407 485 8.99E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 SUPERFAMILY SSF54980 608 695 2.83E-30 T 28-03-2018 IPR035647 EF-G domain III/V-like A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 Pfam PF00679 Elongation factor G C-terminus 605 691 1.8E-31 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 Hamap MF_00054_B Elongation factor G [fusA]. 6 697 111.653 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 SUPERFAMILY SSF50447 271 409 2.21E-36 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 SUPERFAMILY SSF54211 484 604 3.54E-47 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 Gene3D G3DSA:3.30.70.240 614 692 7.5E-33 T 28-03-2018 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 Pfam PF03144 Elongation factor Tu domain 2 329 396 4.8E-18 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 Gene3D G3DSA:2.40.30.10 294 406 9.3E-32 T 28-03-2018 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 Gene3D G3DSA:3.30.230.10 497 613 2.1E-44 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 Gene3D G3DSA:3.30.70.870 407 496 7.9E-36 T 28-03-2018 A6A12_RS01370 ec8249aa70b28a46f19fc4a459e51ead 698 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 697 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS05870 1e38ca23e432d93229b7a804ff3de242 284 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 82 91 - T 28-03-2018 IPR024002 Formate/nitrite transporter, conserved site A6A12_RS05870 1e38ca23e432d93229b7a804ff3de242 284 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 25 279 1.0E-77 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 A6A12_RS05870 1e38ca23e432d93229b7a804ff3de242 284 Gene3D G3DSA:1.20.1080.10 10 284 8.5E-81 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 A6A12_RS05870 1e38ca23e432d93229b7a804ff3de242 284 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 167 177 - T 28-03-2018 IPR024002 Formate/nitrite transporter, conserved site A6A12_RS05870 1e38ca23e432d93229b7a804ff3de242 284 TIGRFAM TIGR04060 formate_focA: formate transporter FocA 13 278 8.5E-115 T 28-03-2018 IPR023999 Formate transporter FocA, putative GO:0015499|GO:0015724|GO:0016021 A6A12_RS05870 1e38ca23e432d93229b7a804ff3de242 284 Pfam PF01226 Formate/nitrite transporter 13 275 9.4E-75 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 A6A12_RS04145 729ce13d919f47bd19ab811c778a2a8f 183 PIRSF PIRSF004682 1 182 2.4E-64 T 28-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 A6A12_RS04145 729ce13d919f47bd19ab811c778a2a8f 183 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 5 154 6.7E-36 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A6A12_RS04145 729ce13d919f47bd19ab811c778a2a8f 183 Gene3D G3DSA:3.40.50.1000 2 182 4.4E-31 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS04145 729ce13d919f47bd19ab811c778a2a8f 183 SUPERFAMILY SSF56784 4 181 3.03E-49 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS04145 729ce13d919f47bd19ab811c778a2a8f 183 Pfam PF13242 HAD-hyrolase-like 107 176 2.5E-13 T 28-03-2018 A6A12_RS04145 729ce13d919f47bd19ab811c778a2a8f 183 TIGRFAM TIGR00213 GmhB_yaeD: D,D-heptose 1,7-bisphosphate phosphatase 4 178 3.2E-80 T 28-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 A6A12_RS04145 729ce13d919f47bd19ab811c778a2a8f 183 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 4 153 1.1E-38 T 28-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 A6A12_RS05840 c700892ead690bc131a5a08de34c572b 192 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 173 186 - T 28-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A6A12_RS05840 c700892ead690bc131a5a08de34c572b 192 SUPERFAMILY SSF52540 2 141 8.86E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05840 c700892ead690bc131a5a08de34c572b 192 Hamap MF_00124 Thymidine kinase [tdk]. 1 189 34.353 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A6A12_RS05840 c700892ead690bc131a5a08de34c572b 192 PIRSF PIRSF035805 1 192 1.6E-57 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A6A12_RS05840 c700892ead690bc131a5a08de34c572b 192 SUPERFAMILY SSF57716 142 190 2.33E-16 T 28-03-2018 A6A12_RS05840 c700892ead690bc131a5a08de34c572b 192 Gene3D G3DSA:3.40.50.300 2 141 2.5E-43 T 28-03-2018 A6A12_RS05840 c700892ead690bc131a5a08de34c572b 192 Gene3D G3DSA:3.30.60.20 142 192 5.4E-18 T 28-03-2018 A6A12_RS05840 c700892ead690bc131a5a08de34c572b 192 Pfam PF00265 Thymidine kinase 2 186 3.5E-61 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A6A12_RS06060 d50d17b8015ace281a2729353bbe23c3 92 Pfam PF01386 Ribosomal L25p family 4 89 1.1E-23 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A6A12_RS06060 d50d17b8015ace281a2729353bbe23c3 92 SUPERFAMILY SSF50715 1 92 1.03E-28 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A6A12_RS06060 d50d17b8015ace281a2729353bbe23c3 92 Gene3D G3DSA:2.40.240.10 1 92 2.8E-28 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A6A12_RS06060 d50d17b8015ace281a2729353bbe23c3 92 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 1 92 26.314 T 28-03-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 A6A12_RS06060 d50d17b8015ace281a2729353bbe23c3 92 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 1 92 2.0E-43 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 A6A12_RS10295 8400da06c93d6b6acd7f152f909dc40d 117 Pfam PF13698 Domain of unknown function (DUF4156) 25 108 1.8E-18 T 28-03-2018 IPR025294 Protein of unknown function DUF4156 A6A12_RS07750 ebba5331f509008286a4135d9d6272cd 1150 Pfam PF06744 Type VI secretion protein IcmF C-terminal 899 1098 1.3E-44 T 28-03-2018 IPR010623 Type VI secretion system IcmF, C-terminal A6A12_RS07750 ebba5331f509008286a4135d9d6272cd 1150 Pfam PF14331 ImcF-related N-terminal domain 167 419 2.0E-58 T 28-03-2018 IPR025743 ImcF-related, N-terminal domain A6A12_RS07750 ebba5331f509008286a4135d9d6272cd 1150 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 26 1148 2.8E-175 T 28-03-2018 IPR017731 Type VI secretion system, IcmF A6A12_RS07750 ebba5331f509008286a4135d9d6272cd 1150 Pfam PF06761 Intracellular multiplication and human macrophage-killing 474 768 1.2E-48 T 28-03-2018 IPR009612 ImcF-related A6A12_RS06620 662b6b86eb1cf045db48efe7f8841b39 336 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 292 312 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A6A12_RS06620 662b6b86eb1cf045db48efe7f8841b39 336 SUPERFAMILY SSF51395 1 336 2.24E-107 T 28-03-2018 A6A12_RS06620 662b6b86eb1cf045db48efe7f8841b39 336 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 2 336 51.194 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A6A12_RS06620 662b6b86eb1cf045db48efe7f8841b39 336 PIRSF PIRSF000164 10 336 8.0E-103 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 A6A12_RS06620 662b6b86eb1cf045db48efe7f8841b39 336 Gene3D G3DSA:3.20.20.70 1 336 2.7E-79 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS06620 662b6b86eb1cf045db48efe7f8841b39 336 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 80 99 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A6A12_RS06620 662b6b86eb1cf045db48efe7f8841b39 336 Pfam PF01180 Dihydroorotate dehydrogenase 47 336 6.6E-91 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A6A12_RS06620 662b6b86eb1cf045db48efe7f8841b39 336 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 3 336 5.7E-149 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 A6A12_RS04380 2c34d8c2461bc1774a2a399fff7bba74 341 Gene3D G3DSA:1.10.8.60 142 219 2.0E-18 T 28-03-2018 A6A12_RS04380 2c34d8c2461bc1774a2a399fff7bba74 341 SUPERFAMILY SSF52540 1 208 7.65E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS04380 2c34d8c2461bc1774a2a399fff7bba74 341 Pfam PF06144 DNA polymerase III, delta subunit 20 189 2.0E-46 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 A6A12_RS04380 2c34d8c2461bc1774a2a399fff7bba74 341 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 214 331 1.0E-33 T 28-03-2018 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS04380 2c34d8c2461bc1774a2a399fff7bba74 341 Gene3D G3DSA:3.40.50.300 1 139 6.2E-22 T 28-03-2018 A6A12_RS04380 2c34d8c2461bc1774a2a399fff7bba74 341 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 17 331 5.2E-103 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 A6A12_RS04380 2c34d8c2461bc1774a2a399fff7bba74 341 SUPERFAMILY SSF48019 211 332 6.63E-32 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A6A12_RS04380 2c34d8c2461bc1774a2a399fff7bba74 341 Gene3D G3DSA:1.20.272.10 220 339 4.2E-24 T 28-03-2018 A6A12_RS12145 6c971a880ec802036b069c9a369428bf 187 Gene3D G3DSA:2.60.450.10 88 185 7.6E-7 T 28-03-2018 A6A12_RS12145 6c971a880ec802036b069c9a369428bf 187 PIRSF PIRSF028513 2 185 4.7E-28 T 28-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 A6A12_RS12145 6c971a880ec802036b069c9a369428bf 187 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 8 183 2.4E-43 T 28-03-2018 IPR010664 Lipopolysaccharide assembly, LptC-related A6A12_RS12145 6c971a880ec802036b069c9a369428bf 187 Hamap MF_01915 Lipopolysaccharide export system protein LptC [lptC]. 3 185 23.89 T 28-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 A6A12_RS12145 6c971a880ec802036b069c9a369428bf 187 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 5 182 2.1E-45 T 28-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 A6A12_RS09925 c07c4be7e3b28f7413a347b27b30a0ac 495 SMART SM00382 281 419 1.7E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS09925 c07c4be7e3b28f7413a347b27b30a0ac 495 SUPERFAMILY SSF52540 278 470 4.46E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09925 c07c4be7e3b28f7413a347b27b30a0ac 495 Pfam PF00448 SRP54-type protein, GTPase domain 284 472 6.0E-39 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A6A12_RS09925 c07c4be7e3b28f7413a347b27b30a0ac 495 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 2 370 2.5E-86 T 28-03-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 A6A12_RS09925 c07c4be7e3b28f7413a347b27b30a0ac 495 Gene3D G3DSA:3.40.50.300 279 476 8.0E-24 T 28-03-2018 A6A12_RS09925 c07c4be7e3b28f7413a347b27b30a0ac 495 SMART SM00962 282 475 1.1E-65 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A6A12_RS12905 f49a1294bfaae3aea0a2592a96352fa6 733 Hamap MF_00983 Probable primosomal protein N' [priA]. 8 732 25.298 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 A6A12_RS12905 f49a1294bfaae3aea0a2592a96352fa6 733 SUPERFAMILY SSF52540 461 614 1.21E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12905 f49a1294bfaae3aea0a2592a96352fa6 733 SUPERFAMILY SSF52540 168 379 1.7E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12905 f49a1294bfaae3aea0a2592a96352fa6 733 Gene3D G3DSA:3.40.50.300 197 361 6.3E-27 T 28-03-2018 A6A12_RS12905 f49a1294bfaae3aea0a2592a96352fa6 733 Pfam PF00271 Helicase conserved C-terminal domain 513 588 5.7E-7 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS12905 f49a1294bfaae3aea0a2592a96352fa6 733 SMART SM00487 196 391 5.4E-17 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS12905 f49a1294bfaae3aea0a2592a96352fa6 733 SMART SM00490 492 589 2.3E-10 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS12905 f49a1294bfaae3aea0a2592a96352fa6 733 Gene3D G3DSA:3.40.50.300 400 630 2.8E-24 T 28-03-2018 A6A12_RS12905 f49a1294bfaae3aea0a2592a96352fa6 733 TIGRFAM TIGR00595 priA: primosomal protein N' 221 729 5.3E-191 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 A6A12_RS12905 f49a1294bfaae3aea0a2592a96352fa6 733 Pfam PF00270 DEAD/DEAH box helicase 204 364 2.9E-14 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A6A12_RS12505 95fd38a5f30045ecfecc026b9f7855cc 209 Gene3D G3DSA:4.10.960.10 57 165 7.0E-37 T 28-03-2018 A6A12_RS12505 95fd38a5f30045ecfecc026b9f7855cc 209 ProSitePatterns PS00474 Ribosomal protein L3 signature. 101 124 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site A6A12_RS12505 95fd38a5f30045ecfecc026b9f7855cc 209 Pfam PF00297 Ribosomal protein L3 64 182 7.4E-16 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12505 95fd38a5f30045ecfecc026b9f7855cc 209 SUPERFAMILY SSF50447 1 208 8.12E-84 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A6A12_RS12505 95fd38a5f30045ecfecc026b9f7855cc 209 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 207 41.23 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12505 95fd38a5f30045ecfecc026b9f7855cc 209 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 204 1.5E-94 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02705 c7e10831fad976167c191e9c1cb81c1c 264 PIRSF PIRSF000388 1 264 4.1E-102 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A6A12_RS02705 c7e10831fad976167c191e9c1cb81c1c 264 Gene3D G3DSA:3.20.20.60 1 263 7.1E-82 T 28-03-2018 A6A12_RS02705 c7e10831fad976167c191e9c1cb81c1c 264 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 263 41.312 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A6A12_RS02705 c7e10831fad976167c191e9c1cb81c1c 264 Pfam PF02548 Ketopantoate hydroxymethyltransferase 3 258 5.2E-108 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A6A12_RS02705 c7e10831fad976167c191e9c1cb81c1c 264 SUPERFAMILY SSF51621 3 262 2.56E-105 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A6A12_RS02705 c7e10831fad976167c191e9c1cb81c1c 264 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 1 262 6.7E-115 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A6A12_RS01900 8cbc37c98f407d332a5ce0e098fa044a 199 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 194 6.0E-66 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 A6A12_RS01900 8cbc37c98f407d332a5ce0e098fa044a 199 Pfam PF01725 Ham1 family 4 192 1.9E-55 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 A6A12_RS01900 8cbc37c98f407d332a5ce0e098fa044a 199 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 196 49.929 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 A6A12_RS01900 8cbc37c98f407d332a5ce0e098fa044a 199 Gene3D G3DSA:3.90.950.10 1 199 1.6E-79 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A6A12_RS01900 8cbc37c98f407d332a5ce0e098fa044a 199 SUPERFAMILY SSF52972 1 195 2.88E-73 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A6A12_RS01045 ab1f8633938440a53fab9866b22abc53 108 PRINTS PR00421 Thioredoxin family signature 24 32 3.3E-10 T 28-03-2018 A6A12_RS01045 ab1f8633938440a53fab9866b22abc53 108 PRINTS PR00421 Thioredoxin family signature 72 83 3.3E-10 T 28-03-2018 A6A12_RS01045 ab1f8633938440a53fab9866b22abc53 108 PRINTS PR00421 Thioredoxin family signature 32 41 3.3E-10 T 28-03-2018 A6A12_RS01045 ab1f8633938440a53fab9866b22abc53 108 SUPERFAMILY SSF52833 3 107 5.03E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS01045 ab1f8633938440a53fab9866b22abc53 108 Gene3D G3DSA:3.40.30.10 1 108 7.4E-32 T 28-03-2018 A6A12_RS01045 ab1f8633938440a53fab9866b22abc53 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A6A12_RS01045 ab1f8633938440a53fab9866b22abc53 108 Pfam PF00085 Thioredoxin 5 106 6.1E-33 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 A6A12_RS01045 ab1f8633938440a53fab9866b22abc53 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 1.8E-37 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A6A12_RS01045 ab1f8633938440a53fab9866b22abc53 108 PIRSF PIRSF000077 2 108 7.3E-43 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 A6A12_RS02805 a04900dc9ce5e5a8b7929e119de0fbfc 801 Pfam PF06165 Glycosyltransferase family 36 21 267 3.8E-83 T 28-03-2018 IPR010383 Glycosyl hydrolase 94 A6A12_RS02805 a04900dc9ce5e5a8b7929e119de0fbfc 801 SUPERFAMILY SSF74650 1 269 1.35E-81 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 A6A12_RS02805 a04900dc9ce5e5a8b7929e119de0fbfc 801 SMART SM01068 1 63 2.6E-19 T 28-03-2018 IPR009342 Putative carbohydrate binding domain A6A12_RS02805 a04900dc9ce5e5a8b7929e119de0fbfc 801 Gene3D G3DSA:1.50.10.10 311 694 6.0E-72 T 28-03-2018 A6A12_RS02805 a04900dc9ce5e5a8b7929e119de0fbfc 801 Gene3D G3DSA:2.70.98.40 1 277 6.5E-83 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 A6A12_RS02805 a04900dc9ce5e5a8b7929e119de0fbfc 801 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 296 727 8.8E-210 T 28-03-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain A6A12_RS02805 a04900dc9ce5e5a8b7929e119de0fbfc 801 Gene3D G3DSA:2.60.420.10 718 801 9.7E-27 T 28-03-2018 A6A12_RS02805 a04900dc9ce5e5a8b7929e119de0fbfc 801 SUPERFAMILY SSF48208 274 800 1.87E-111 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 A6A12_RS05530 b5cc8d23ad7c3c4702544923a538a166 560 Hamap MF_01015 Putative transport protein YbjL [ybjL]. 1 560 58.836 T 28-03-2018 IPR023017 Transport protein YbjL, putative A6A12_RS05530 b5cc8d23ad7c3c4702544923a538a166 560 Gene3D G3DSA:3.30.70.1450 299 378 1.4E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS05530 b5cc8d23ad7c3c4702544923a538a166 560 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 21 172 1.2E-29 T 28-03-2018 IPR006512 YidE/YbjL duplication A6A12_RS05530 b5cc8d23ad7c3c4702544923a538a166 560 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 393 544 2.4E-38 T 28-03-2018 IPR006512 YidE/YbjL duplication A6A12_RS05530 b5cc8d23ad7c3c4702544923a538a166 560 Gene3D G3DSA:3.30.70.1450 221 294 1.7E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS05530 b5cc8d23ad7c3c4702544923a538a166 560 SUPERFAMILY SSF116726 230 285 2.49E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS05530 b5cc8d23ad7c3c4702544923a538a166 560 Pfam PF02080 TrkA-C domain 230 281 7.9E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS05530 b5cc8d23ad7c3c4702544923a538a166 560 Pfam PF02080 TrkA-C domain 309 374 5.0E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS05530 b5cc8d23ad7c3c4702544923a538a166 560 Pfam PF06826 Predicted Permease Membrane Region 17 185 1.5E-36 T 28-03-2018 IPR006512 YidE/YbjL duplication A6A12_RS05530 b5cc8d23ad7c3c4702544923a538a166 560 Pfam PF06826 Predicted Permease Membrane Region 389 557 2.7E-43 T 28-03-2018 IPR006512 YidE/YbjL duplication A6A12_RS05530 b5cc8d23ad7c3c4702544923a538a166 560 SUPERFAMILY SSF116726 294 377 1.7E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS11520 d811635457a8eff1777433fc3f11a862 486 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 25 473 2.1E-186 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS11520 d811635457a8eff1777433fc3f11a862 486 Gene3D G3DSA:3.90.190.20 328 477 9.2E-35 T 28-03-2018 A6A12_RS11520 d811635457a8eff1777433fc3f11a862 486 SUPERFAMILY SSF53244 326 473 1.28E-46 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A6A12_RS11520 d811635457a8eff1777433fc3f11a862 486 Pfam PF02875 Mur ligase family, glutamate ligase domain 329 417 8.1E-21 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A6A12_RS11520 d811635457a8eff1777433fc3f11a862 486 SUPERFAMILY SSF51984 23 109 3.66E-26 T 28-03-2018 A6A12_RS11520 d811635457a8eff1777433fc3f11a862 486 SUPERFAMILY SSF53623 108 323 9.29E-73 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS11520 d811635457a8eff1777433fc3f11a862 486 Pfam PF01225 Mur ligase family, catalytic domain 25 121 5.0E-27 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A6A12_RS11520 d811635457a8eff1777433fc3f11a862 486 Pfam PF08245 Mur ligase middle domain 127 307 8.2E-29 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS11520 d811635457a8eff1777433fc3f11a862 486 Gene3D G3DSA:3.40.1190.10 111 327 5.2E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS11520 d811635457a8eff1777433fc3f11a862 486 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 22 479 43.193 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS11520 d811635457a8eff1777433fc3f11a862 486 Gene3D G3DSA:3.40.50.720 4 110 1.0E-16 T 28-03-2018 A6A12_RS14095 e968eb5c53de629d21fd295864e499ee 201 Gene3D G3DSA:3.30.1050.10 8 120 2.2E-5 T 28-03-2018 IPR003033 SCP2 sterol-binding domain A6A12_RS14095 e968eb5c53de629d21fd295864e499ee 201 SUPERFAMILY SSF55718 15 117 1.51E-7 T 28-03-2018 IPR003033 SCP2 sterol-binding domain A6A12_RS14095 e968eb5c53de629d21fd295864e499ee 201 Pfam PF02036 SCP-2 sterol transfer family 15 111 1.5E-20 T 28-03-2018 IPR003033 SCP2 sterol-binding domain A6A12_RS12380 a6ed928bd72fd3a037d901fc13a0968b 330 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 62 157 1.2E-23 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS12380 a6ed928bd72fd3a037d901fc13a0968b 330 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 5 318 34.681 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS12380 a6ed928bd72fd3a037d901fc13a0968b 330 SUPERFAMILY SSF47789 252 326 1.44E-25 T 28-03-2018 A6A12_RS12380 a6ed928bd72fd3a037d901fc13a0968b 330 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 257 330 2.0E-36 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS12380 a6ed928bd72fd3a037d901fc13a0968b 330 SUPERFAMILY SSF56553 53 179 2.44E-40 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS12380 a6ed928bd72fd3a037d901fc13a0968b 330 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 29 229 2.5E-23 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS12380 a6ed928bd72fd3a037d901fc13a0968b 330 SMART SM00662 23 235 5.7E-103 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS12380 a6ed928bd72fd3a037d901fc13a0968b 330 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 24 317 1.3E-111 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS12380 a6ed928bd72fd3a037d901fc13a0968b 330 Gene3D G3DSA:1.10.150.20 246 329 8.6E-29 T 28-03-2018 A6A12_RS12380 a6ed928bd72fd3a037d901fc13a0968b 330 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 246 309 7.1E-24 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS12380 a6ed928bd72fd3a037d901fc13a0968b 330 Gene3D G3DSA:3.30.1360.10 119 232 1.4E-27 T 28-03-2018 A6A12_RS12380 a6ed928bd72fd3a037d901fc13a0968b 330 Gene3D G3DSA:3.30.1360.10 4 89 1.4E-19 T 28-03-2018 A6A12_RS12380 a6ed928bd72fd3a037d901fc13a0968b 330 SUPERFAMILY SSF55257 7 53 3.93E-30 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS12380 a6ed928bd72fd3a037d901fc13a0968b 330 SUPERFAMILY SSF55257 180 234 3.93E-30 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS11915 e44c3bf6716cfaeda07216c74ddc8afd 649 SUPERFAMILY SSF56801 383 644 2.75E-112 T 28-03-2018 A6A12_RS11915 e44c3bf6716cfaeda07216c74ddc8afd 649 SUPERFAMILY SSF56801 52 332 2.75E-112 T 28-03-2018 A6A12_RS11915 e44c3bf6716cfaeda07216c74ddc8afd 649 Pfam PF00501 AMP-binding enzyme 68 513 9.8E-98 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A6A12_RS11915 e44c3bf6716cfaeda07216c74ddc8afd 649 ProSitePatterns PS00455 Putative AMP-binding domain signature. 230 241 - T 28-03-2018 IPR020845 AMP-binding, conserved site A6A12_RS11915 e44c3bf6716cfaeda07216c74ddc8afd 649 Gene3D G3DSA:3.40.50.980 54 234 3.1E-35 T 28-03-2018 A6A12_RS11915 e44c3bf6716cfaeda07216c74ddc8afd 649 Gene3D G3DSA:3.30.300.30 508 644 6.9E-16 T 28-03-2018 A6A12_RS11915 e44c3bf6716cfaeda07216c74ddc8afd 649 Gene3D G3DSA:2.30.38.10 432 506 5.6E-17 T 28-03-2018 A6A12_RS11915 e44c3bf6716cfaeda07216c74ddc8afd 649 Gene3D G3DSA:3.40.50.980 235 431 9.2E-43 T 28-03-2018 A6A12_RS09570 4fe59d74616d62a275e31777682cd64b 404 Gene3D G3DSA:3.90.1150.10 281 404 1.8E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS09570 4fe59d74616d62a275e31777682cd64b 404 Gene3D G3DSA:3.40.640.10 53 280 1.2E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS09570 4fe59d74616d62a275e31777682cd64b 404 SUPERFAMILY SSF53383 5 400 1.34E-94 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS09570 4fe59d74616d62a275e31777682cd64b 404 Pfam PF00155 Aminotransferase class I and II 61 390 3.7E-47 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A6A12_RS11545 273eee6ad7ba830e8cf34efca056284a 452 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 29 447 1.6E-139 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS11545 273eee6ad7ba830e8cf34efca056284a 452 Pfam PF08245 Mur ligase middle domain 105 293 2.1E-45 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS11545 273eee6ad7ba830e8cf34efca056284a 452 SUPERFAMILY SSF53623 101 310 2.35E-51 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS11545 273eee6ad7ba830e8cf34efca056284a 452 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 448 32.969 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS11545 273eee6ad7ba830e8cf34efca056284a 452 Gene3D G3DSA:3.40.1390.10 2 89 1.9E-26 T 28-03-2018 A6A12_RS11545 273eee6ad7ba830e8cf34efca056284a 452 SUPERFAMILY SSF63418 1 96 1.1E-26 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A6A12_RS11545 273eee6ad7ba830e8cf34efca056284a 452 SUPERFAMILY SSF53244 313 447 6.1E-33 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A6A12_RS11545 273eee6ad7ba830e8cf34efca056284a 452 Gene3D G3DSA:3.40.1190.10 90 309 5.8E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS11545 273eee6ad7ba830e8cf34efca056284a 452 Gene3D G3DSA:3.90.190.20 313 452 5.4E-35 T 28-03-2018 A6A12_RS11545 273eee6ad7ba830e8cf34efca056284a 452 Pfam PF02875 Mur ligase family, glutamate ligase domain 313 389 2.4E-13 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A6A12_RS11545 273eee6ad7ba830e8cf34efca056284a 452 Pfam PF01225 Mur ligase family, catalytic domain 24 89 5.7E-10 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A6A12_RS09825 a4bd68d3af8c0c74e2f14a06264ae0b5 254 Pfam PF04333 MlaA lipoprotein 39 229 2.8E-62 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 A6A12_RS09825 a4bd68d3af8c0c74e2f14a06264ae0b5 254 PRINTS PR01805 VacJ lipoprotein signature 39 52 3.0E-29 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 A6A12_RS09825 a4bd68d3af8c0c74e2f14a06264ae0b5 254 PRINTS PR01805 VacJ lipoprotein signature 57 73 3.0E-29 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 A6A12_RS09825 a4bd68d3af8c0c74e2f14a06264ae0b5 254 PRINTS PR01805 VacJ lipoprotein signature 108 125 3.0E-29 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 A6A12_RS09825 a4bd68d3af8c0c74e2f14a06264ae0b5 254 PRINTS PR01805 VacJ lipoprotein signature 145 162 3.0E-29 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 A6A12_RS08190 0d5709761378afe33a2421e51c03aac4 787 Gene3D G3DSA:3.90.1600.10 391 604 4.2E-50 T 28-03-2018 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS08190 0d5709761378afe33a2421e51c03aac4 787 SMART SM00486 153 558 1.5E-67 T 28-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS08190 0d5709761378afe33a2421e51c03aac4 787 ProSitePatterns PS00116 DNA polymerase family B signature. 546 554 - T 28-03-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS08190 0d5709761378afe33a2421e51c03aac4 787 SUPERFAMILY SSF56672 385 781 1.17E-114 T 28-03-2018 A6A12_RS08190 0d5709761378afe33a2421e51c03aac4 787 Gene3D G3DSA:3.30.420.10 60 347 2.6E-40 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS08190 0d5709761378afe33a2421e51c03aac4 787 Pfam PF03104 DNA polymerase family B, exonuclease domain 183 296 9.1E-14 T 28-03-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS08190 0d5709761378afe33a2421e51c03aac4 787 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 415 428 3.2E-10 T 28-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS08190 0d5709761378afe33a2421e51c03aac4 787 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 544 552 3.2E-10 T 28-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS08190 0d5709761378afe33a2421e51c03aac4 787 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 492 504 3.2E-10 T 28-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS08190 0d5709761378afe33a2421e51c03aac4 787 Pfam PF00136 DNA polymerase family B 376 742 3.4E-43 T 28-03-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS08190 0d5709761378afe33a2421e51c03aac4 787 SUPERFAMILY SSF53098 4 389 2.78E-83 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS06745 ff56d92e89ebe2b09f3b40c9c90ab406 310 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 11 270 57.663 T 28-03-2018 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 A6A12_RS06745 ff56d92e89ebe2b09f3b40c9c90ab406 310 Gene3D G3DSA:3.40.50.620 6 243 2.9E-40 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS06745 ff56d92e89ebe2b09f3b40c9c90ab406 310 PIRSF PIRSF004976 1 272 2.4E-76 T 28-03-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 A6A12_RS06745 ff56d92e89ebe2b09f3b40c9c90ab406 310 Pfam PF01171 PP-loop family 43 204 2.3E-15 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A6A12_RS06745 ff56d92e89ebe2b09f3b40c9c90ab406 310 SUPERFAMILY SSF52402 18 237 9.48E-57 T 28-03-2018 A6A12_RS09145 cafecda7963227fa9b24b2d97ab4121d 449 Gene3D G3DSA:1.10.3710.10 349 449 3.0E-33 T 28-03-2018 A6A12_RS09145 cafecda7963227fa9b24b2d97ab4121d 449 SUPERFAMILY SSF48019 253 435 1.98E-71 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A6A12_RS09145 cafecda7963227fa9b24b2d97ab4121d 449 Pfam PF12002 MgsA AAA+ ATPase C terminal 269 435 3.0E-66 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal A6A12_RS09145 cafecda7963227fa9b24b2d97ab4121d 449 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 54 159 7.9E-17 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A6A12_RS09145 cafecda7963227fa9b24b2d97ab4121d 449 Gene3D G3DSA:1.10.8.60 155 244 3.4E-17 T 28-03-2018 A6A12_RS09145 cafecda7963227fa9b24b2d97ab4121d 449 SUPERFAMILY SSF52540 11 235 1.07E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09145 cafecda7963227fa9b24b2d97ab4121d 449 SMART SM00382 50 166 1.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS09145 cafecda7963227fa9b24b2d97ab4121d 449 Gene3D G3DSA:3.40.50.300 8 154 3.9E-31 T 28-03-2018 A6A12_RS09145 cafecda7963227fa9b24b2d97ab4121d 449 Gene3D G3DSA:1.20.272.10 253 347 7.6E-37 T 28-03-2018 A6A12_RS09145 cafecda7963227fa9b24b2d97ab4121d 449 Pfam PF16193 AAA C-terminal domain 191 268 9.0E-21 T 28-03-2018 IPR032423 AAA C-terminal domain A6A12_RS04735 80e63dae34c3410142428bc35b54f037 761 Gene3D G3DSA:2.60.40.10 167 256 3.6E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS04735 80e63dae34c3410142428bc35b54f037 761 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 728 746 - T 28-03-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A6A12_RS04735 80e63dae34c3410142428bc35b54f037 761 Pfam PF00759 Glycosyl hydrolase family 9 260 751 7.1E-100 T 28-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A6A12_RS04735 80e63dae34c3410142428bc35b54f037 761 Gene3D G3DSA:2.60.120.260 19 159 6.3E-22 T 28-03-2018 IPR008979 Galactose-binding domain-like A6A12_RS04735 80e63dae34c3410142428bc35b54f037 761 Gene3D G3DSA:1.50.10.10 258 759 1.7E-118 T 28-03-2018 A6A12_RS04735 80e63dae34c3410142428bc35b54f037 761 Pfam PF02927 Cellulase N-terminal ig-like domain 170 237 6.0E-12 T 28-03-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 A6A12_RS04735 80e63dae34c3410142428bc35b54f037 761 Pfam PF02018 Carbohydrate binding domain 22 144 1.7E-14 T 28-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 A6A12_RS04735 80e63dae34c3410142428bc35b54f037 761 SUPERFAMILY SSF49785 21 158 1.68E-29 T 28-03-2018 IPR008979 Galactose-binding domain-like A6A12_RS04735 80e63dae34c3410142428bc35b54f037 761 SUPERFAMILY SSF48208 257 756 1.87E-116 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 A6A12_RS04735 80e63dae34c3410142428bc35b54f037 761 ProSitePatterns PS00592 Glycosyl hydrolases family 9 active sites signature 1. 667 683 - T 28-03-2018 IPR018221 Glycoside hydrolase family 9, His active site KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A6A12_RS04735 80e63dae34c3410142428bc35b54f037 761 SUPERFAMILY SSF81296 170 256 1.05E-12 T 28-03-2018 IPR014756 Immunoglobulin E-set A6A12_RS04750 aeea7352e1ad5a2affcdff0569b8d934 468 Gene3D G3DSA:3.40.50.300 142 319 3.0E-26 T 28-03-2018 A6A12_RS04750 aeea7352e1ad5a2affcdff0569b8d934 468 SUPERFAMILY SSF52172 13 191 1.41E-40 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS04750 aeea7352e1ad5a2affcdff0569b8d934 468 Pfam PF00158 Sigma-54 interaction domain 148 313 8.1E-69 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 A6A12_RS04750 aeea7352e1ad5a2affcdff0569b8d934 468 Gene3D G3DSA:1.10.8.60 320 387 2.0E-19 T 28-03-2018 A6A12_RS04750 aeea7352e1ad5a2affcdff0569b8d934 468 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 360 369 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site A6A12_RS04750 aeea7352e1ad5a2affcdff0569b8d934 468 Gene3D G3DSA:1.10.10.60 388 463 7.1E-13 T 28-03-2018 A6A12_RS04750 aeea7352e1ad5a2affcdff0569b8d934 468 SUPERFAMILY SSF52540 147 390 2.59E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS04750 aeea7352e1ad5a2affcdff0569b8d934 468 Gene3D G3DSA:3.40.50.2300 5 131 1.4E-31 T 28-03-2018 A6A12_RS04750 aeea7352e1ad5a2affcdff0569b8d934 468 Pfam PF00072 Response regulator receiver domain 14 122 5.1E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS04750 aeea7352e1ad5a2affcdff0569b8d934 468 SMART SM00448 11 122 3.1E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS04750 aeea7352e1ad5a2affcdff0569b8d934 468 SMART SM00382 167 310 4.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS04750 aeea7352e1ad5a2affcdff0569b8d934 468 SUPERFAMILY SSF46689 419 463 2.0E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS04750 aeea7352e1ad5a2affcdff0569b8d934 468 Pfam PF02954 Bacterial regulatory protein, Fis family 422 462 4.4E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 A6A12_RS04750 aeea7352e1ad5a2affcdff0569b8d934 468 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 233 248 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 A6A12_RS07180 4c25e553483948b8e53c5afe3a0a11eb 168 Gene3D G3DSA:1.10.3680.10 27 168 3.1E-29 T 28-03-2018 IPR029024 TerB-like A6A12_RS07180 4c25e553483948b8e53c5afe3a0a11eb 168 Pfam PF05099 Tellurite resistance protein TerB 28 164 1.2E-35 T 28-03-2018 IPR007791 Co-chaperone DjlA, N-terminal A6A12_RS07180 4c25e553483948b8e53c5afe3a0a11eb 168 SUPERFAMILY SSF158682 19 166 2.22E-29 T 28-03-2018 A6A12_RS12475 8d8426e66f417d387b043734771d00d5 232 Gene3D G3DSA:3.30.300.20 17 107 1.0E-26 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A6A12_RS12475 8d8426e66f417d387b043734771d00d5 232 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 2.3E-98 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A6A12_RS12475 8d8426e66f417d387b043734771d00d5 232 SUPERFAMILY SSF54821 108 206 1.7E-40 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12475 8d8426e66f417d387b043734771d00d5 232 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.846 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 A6A12_RS12475 8d8426e66f417d387b043734771d00d5 232 Pfam PF07650 KH domain 38 111 5.3E-19 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12475 8d8426e66f417d387b043734771d00d5 232 SUPERFAMILY SSF54814 2 106 1.78E-36 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 A6A12_RS12475 8d8426e66f417d387b043734771d00d5 232 SMART SM00322 60 125 1.8E-7 T 28-03-2018 IPR004087 K Homology domain GO:0003676 A6A12_RS12475 8d8426e66f417d387b043734771d00d5 232 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 8.4E-42 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12475 8d8426e66f417d387b043734771d00d5 232 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12475 8d8426e66f417d387b043734771d00d5 232 Gene3D G3DSA:3.30.1140.32 108 207 1.3E-39 T 28-03-2018 A6A12_RS10535 d6a4f9b21b1e98117e5149c54baa990f 290 Gene3D G3DSA:3.30.70.890 162 280 1.0E-24 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A6A12_RS10535 d6a4f9b21b1e98117e5149c54baa990f 290 Pfam PF00288 GHMP kinases N terminal domain 89 145 2.7E-9 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A6A12_RS10535 d6a4f9b21b1e98117e5149c54baa990f 290 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 6 265 31.534 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A6A12_RS10535 d6a4f9b21b1e98117e5149c54baa990f 290 PIRSF PIRSF010376 5 280 7.8E-87 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A6A12_RS10535 d6a4f9b21b1e98117e5149c54baa990f 290 SUPERFAMILY SSF54211 6 158 1.9E-45 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS10535 d6a4f9b21b1e98117e5149c54baa990f 290 Gene3D G3DSA:3.30.230.10 6 161 1.2E-42 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A6A12_RS10535 d6a4f9b21b1e98117e5149c54baa990f 290 Pfam PF08544 GHMP kinases C terminal 197 258 2.4E-6 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A6A12_RS10535 d6a4f9b21b1e98117e5149c54baa990f 290 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 6 279 4.9E-96 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 A6A12_RS10535 d6a4f9b21b1e98117e5149c54baa990f 290 SUPERFAMILY SSF55060 162 277 1.73E-35 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain A6A12_RS07690 520b6246c2ae7ba52a90371fbc5adc16 117 Pfam PF05717 IS66 Orf2 like protein 9 103 1.8E-32 T 28-03-2018 IPR008878 Transposase IS66, Orf2 A6A12_RS01425 520b6246c2ae7ba52a90371fbc5adc16 117 Pfam PF05717 IS66 Orf2 like protein 9 103 1.8E-32 T 28-03-2018 IPR008878 Transposase IS66, Orf2 A6A12_RS13675 520b6246c2ae7ba52a90371fbc5adc16 117 Pfam PF05717 IS66 Orf2 like protein 9 103 1.8E-32 T 28-03-2018 IPR008878 Transposase IS66, Orf2 A6A12_RS13640 520b6246c2ae7ba52a90371fbc5adc16 117 Pfam PF05717 IS66 Orf2 like protein 9 103 1.8E-32 T 28-03-2018 IPR008878 Transposase IS66, Orf2 A6A12_RS13850 520b6246c2ae7ba52a90371fbc5adc16 117 Pfam PF05717 IS66 Orf2 like protein 9 103 1.8E-32 T 28-03-2018 IPR008878 Transposase IS66, Orf2 A6A12_RS08765 520b6246c2ae7ba52a90371fbc5adc16 117 Pfam PF05717 IS66 Orf2 like protein 9 103 1.8E-32 T 28-03-2018 IPR008878 Transposase IS66, Orf2 A6A12_RS00495 520b6246c2ae7ba52a90371fbc5adc16 117 Pfam PF05717 IS66 Orf2 like protein 9 103 1.8E-32 T 28-03-2018 IPR008878 Transposase IS66, Orf2 A6A12_RS07015 520b6246c2ae7ba52a90371fbc5adc16 117 Pfam PF05717 IS66 Orf2 like protein 9 103 1.8E-32 T 28-03-2018 IPR008878 Transposase IS66, Orf2 A6A12_RS00180 520b6246c2ae7ba52a90371fbc5adc16 117 Pfam PF05717 IS66 Orf2 like protein 9 103 1.8E-32 T 28-03-2018 IPR008878 Transposase IS66, Orf2 A6A12_RS13880 520b6246c2ae7ba52a90371fbc5adc16 117 Pfam PF05717 IS66 Orf2 like protein 9 103 1.8E-32 T 28-03-2018 IPR008878 Transposase IS66, Orf2 A6A12_RS00215 039171b95930b6cedd6aa640d09eacd5 472 Gene3D G3DSA:2.60.40.10 360 472 7.2E-28 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS00215 039171b95930b6cedd6aa640d09eacd5 472 SUPERFAMILY SSF54862 176 335 1.67E-30 T 28-03-2018 A6A12_RS00215 039171b95930b6cedd6aa640d09eacd5 472 SUPERFAMILY SSF54862 107 129 1.67E-30 T 28-03-2018 A6A12_RS00215 039171b95930b6cedd6aa640d09eacd5 472 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 43 470 5.3E-172 T 28-03-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 A6A12_RS00215 039171b95930b6cedd6aa640d09eacd5 472 Gene3D G3DSA:3.30.70.20 280 305 8.0E-5 T 28-03-2018 A6A12_RS00215 039171b95930b6cedd6aa640d09eacd5 472 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 274 285 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A6A12_RS00215 039171b95930b6cedd6aa640d09eacd5 472 Gene3D G3DSA:3.30.70.20 224 279 4.7E-11 T 28-03-2018 A6A12_RS00215 039171b95930b6cedd6aa640d09eacd5 472 Pfam PF13746 4Fe-4S dicluster domain 222 326 9.3E-42 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A6A12_RS00215 039171b95930b6cedd6aa640d09eacd5 472 Pfam PF12801 4Fe-4S binding domain 97 136 1.1E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A6A12_RS00215 039171b95930b6cedd6aa640d09eacd5 472 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 356 469 1.7E-29 T 28-03-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain A6A12_RS00215 039171b95930b6cedd6aa640d09eacd5 472 Gene3D G3DSA:3.30.70.20 306 359 0.0016 T 28-03-2018 A6A12_RS11105 31e3991708ccc8aaef21edf77cdc74a0 227 Gene3D G3DSA:2.60.120.10 36 220 2.0E-11 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS11105 31e3991708ccc8aaef21edf77cdc74a0 227 Pfam PF12973 ChrR Cupin-like domain 136 201 2.5E-13 T 28-03-2018 IPR025979 ChrR-like cupin domain A6A12_RS11105 31e3991708ccc8aaef21edf77cdc74a0 227 SUPERFAMILY SSF51182 117 210 4.69E-13 T 28-03-2018 IPR011051 RmlC-like cupin domain A6A12_RS11105 31e3991708ccc8aaef21edf77cdc74a0 227 TIGRFAM TIGR02451 anti_sig_ChrR: anti-sigma factor, putative, ChrR family 3 224 1.9E-74 T 28-03-2018 IPR012807 Anti-sigma factor ChrR, putative A6A12_RS12190 3f0bdcbb1f61a97a23995c3ad0c988ad 447 Gene3D G3DSA:3.30.2290.10 1 233 1.9E-53 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain A6A12_RS12190 3f0bdcbb1f61a97a23995c3ad0c988ad 447 SUPERFAMILY SSF111283 13 447 2.75E-127 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A6A12_RS12190 3f0bdcbb1f61a97a23995c3ad0c988ad 447 Pfam PF01523 Putative modulator of DNA gyrase 32 324 1.5E-61 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A6A12_RS08815 a4f6a63cee270e06b68966ca44fe7dd5 100 TIGRFAM TIGR02112 cyd_oper_ybgE: cyd operon protein YbgE 9 99 4.6E-38 T 28-03-2018 IPR011846 Cyd operon protein YbgE A6A12_RS08815 a4f6a63cee270e06b68966ca44fe7dd5 100 Pfam PF09600 Cyd operon protein YbgE (Cyd_oper_YbgE) 20 97 1.4E-30 T 28-03-2018 IPR011846 Cyd operon protein YbgE A6A12_RS11260 95be36d82c0b8c07ec28053f0dc7e3dc 382 Gene3D G3DSA:3.30.450.40 19 148 6.8E-8 T 28-03-2018 IPR029016 GAF domain-like A6A12_RS11260 95be36d82c0b8c07ec28053f0dc7e3dc 382 Pfam PF13487 HD domain 243 313 2.2E-12 T 28-03-2018 A6A12_RS11260 95be36d82c0b8c07ec28053f0dc7e3dc 382 SUPERFAMILY SSF109604 188 358 5.97E-23 T 28-03-2018 A6A12_RS11260 95be36d82c0b8c07ec28053f0dc7e3dc 382 SUPERFAMILY SSF55781 34 149 3.36E-12 T 28-03-2018 IPR029016 GAF domain-like A6A12_RS11260 95be36d82c0b8c07ec28053f0dc7e3dc 382 Gene3D G3DSA:1.10.3210.10 149 371 1.5E-25 T 28-03-2018 A6A12_RS04350 d7e08bd36310cb01ddd397d2add37651 392 Gene3D G3DSA:2.60.410.10 303 373 1.2E-20 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A6A12_RS04350 d7e08bd36310cb01ddd397d2add37651 392 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 283 373 1.3E-26 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A6A12_RS04350 d7e08bd36310cb01ddd397d2add37651 392 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 149 162 7.2E-16 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A6A12_RS04350 d7e08bd36310cb01ddd397d2add37651 392 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 122 139 7.2E-16 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A6A12_RS04350 d7e08bd36310cb01ddd397d2add37651 392 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 66 77 7.2E-16 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 A6A12_RS04350 d7e08bd36310cb01ddd397d2add37651 392 SMART SM00936 283 373 1.6E-37 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A6A12_RS04350 d7e08bd36310cb01ddd397d2add37651 392 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 34 263 8.0E-93 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 A6A12_RS04350 d7e08bd36310cb01ddd397d2add37651 392 Gene3D G3DSA:3.40.710.10 10 302 2.0E-53 T 28-03-2018 A6A12_RS04350 d7e08bd36310cb01ddd397d2add37651 392 SUPERFAMILY SSF69189 283 375 1.04E-27 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A6A12_RS04350 d7e08bd36310cb01ddd397d2add37651 392 SUPERFAMILY SSF56601 13 283 5.64E-85 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A6A12_RS00925 c6405dbd00da6307dc1d0e49177a13e0 195 TIGRFAM TIGR03341 YhgI_GntY: IscR-regulated protein YhgI 5 195 9.5E-96 T 28-03-2018 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 A6A12_RS00925 c6405dbd00da6307dc1d0e49177a13e0 195 SUPERFAMILY SSF117916 98 187 1.2E-22 T 28-03-2018 IPR034904 Fe-S cluster assembly domain A6A12_RS00925 c6405dbd00da6307dc1d0e49177a13e0 195 Pfam PF01521 Iron-sulphur cluster biosynthesis 4 101 4.1E-11 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A6A12_RS00925 c6405dbd00da6307dc1d0e49177a13e0 195 Gene3D G3DSA:3.30.300.130 105 191 2.9E-24 T 28-03-2018 IPR034904 Fe-S cluster assembly domain A6A12_RS00925 c6405dbd00da6307dc1d0e49177a13e0 195 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 122 183 4.0E-25 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 A6A12_RS00925 c6405dbd00da6307dc1d0e49177a13e0 195 SUPERFAMILY SSF89360 5 100 3.92E-21 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A6A12_RS00925 c6405dbd00da6307dc1d0e49177a13e0 195 Pfam PF01106 NifU-like domain 114 180 1.8E-19 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 A6A12_RS00925 c6405dbd00da6307dc1d0e49177a13e0 195 Hamap MF_01637 Fe/S biogenesis protein NfuA [nfuA]. 4 195 44.724 T 28-03-2018 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 A6A12_RS00925 c6405dbd00da6307dc1d0e49177a13e0 195 Gene3D G3DSA:2.60.300.12 4 101 1.3E-16 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A6A12_RS00880 ab4e2ada3a309be5ec6b0ff2e66a17ce 192 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 4 183 3.6E-17 T 28-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 A6A12_RS00880 ab4e2ada3a309be5ec6b0ff2e66a17ce 192 PRINTS PR00885 Bacterial general secretion pathway protein H signature 2 16 1.0E-21 T 28-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 A6A12_RS00880 ab4e2ada3a309be5ec6b0ff2e66a17ce 192 PRINTS PR00885 Bacterial general secretion pathway protein H signature 143 158 1.0E-21 T 28-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 A6A12_RS00880 ab4e2ada3a309be5ec6b0ff2e66a17ce 192 PRINTS PR00885 Bacterial general secretion pathway protein H signature 17 31 1.0E-21 T 28-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 A6A12_RS00880 ab4e2ada3a309be5ec6b0ff2e66a17ce 192 Gene3D G3DSA:3.55.40.10 33 191 3.9E-39 T 28-03-2018 A6A12_RS00880 ab4e2ada3a309be5ec6b0ff2e66a17ce 192 Pfam PF12019 Type II transport protein GspH 42 179 6.4E-11 T 28-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 A6A12_RS00880 ab4e2ada3a309be5ec6b0ff2e66a17ce 192 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 26 9.0E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS00880 ab4e2ada3a309be5ec6b0ff2e66a17ce 192 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS00880 ab4e2ada3a309be5ec6b0ff2e66a17ce 192 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 27 2.5E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS00880 ab4e2ada3a309be5ec6b0ff2e66a17ce 192 SUPERFAMILY SSF54523 7 75 8.63E-7 T 28-03-2018 A6A12_RS12200 3aa726947b29099f935c167cf2c20fc4 234 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS12200 3aa726947b29099f935c167cf2c20fc4 234 TIGRFAM TIGR01277 thiQ: thiamine ABC transporter, ATP-binding protein 2 210 4.6E-99 T 28-03-2018 IPR005968 Thiamine ABC transporter, ATP-binding protein ThiQ GO:0005524|GO:0006810|GO:0016021|GO:0042626 A6A12_RS12200 3aa726947b29099f935c167cf2c20fc4 234 Pfam PF00005 ABC transporter 18 157 5.4E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS12200 3aa726947b29099f935c167cf2c20fc4 234 Gene3D G3DSA:3.40.50.300 1 234 3.5E-54 T 28-03-2018 A6A12_RS12200 3aa726947b29099f935c167cf2c20fc4 234 SUPERFAMILY SSF52540 1 230 1.02E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12200 3aa726947b29099f935c167cf2c20fc4 234 SMART SM00382 24 215 8.4E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS14365 44bf653e4fd821e334f7737cf34b8c88 177 SUPERFAMILY SSF47928 3 105 9.02E-29 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14365 44bf653e4fd821e334f7737cf34b8c88 177 PRINTS PR00125 ATP synthase delta subunit signature 74 85 4.2E-28 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14365 44bf653e4fd821e334f7737cf34b8c88 177 PRINTS PR00125 ATP synthase delta subunit signature 150 168 4.2E-28 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14365 44bf653e4fd821e334f7737cf34b8c88 177 PRINTS PR00125 ATP synthase delta subunit signature 135 150 4.2E-28 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14365 44bf653e4fd821e334f7737cf34b8c88 177 PRINTS PR00125 ATP synthase delta subunit signature 7 26 4.2E-28 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14365 44bf653e4fd821e334f7737cf34b8c88 177 PRINTS PR00125 ATP synthase delta subunit signature 85 99 4.2E-28 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14365 44bf653e4fd821e334f7737cf34b8c88 177 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 175 4.8E-64 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14365 44bf653e4fd821e334f7737cf34b8c88 177 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 175 1.8E-53 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14365 44bf653e4fd821e334f7737cf34b8c88 177 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 177 19.098 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14365 44bf653e4fd821e334f7737cf34b8c88 177 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 137 156 - T 28-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14365 44bf653e4fd821e334f7737cf34b8c88 177 Gene3D G3DSA:1.10.520.20 2 106 7.8E-32 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS05365 8d5d7452d1324ca88453635ad2b421f3 129 PIRSF PIRSF007010 1 129 2.9E-49 T 28-03-2018 IPR016502 Type II secretion system (T2SS) pilotin, S protein A6A12_RS05365 8d5d7452d1324ca88453635ad2b421f3 129 Pfam PF16549 Type II secretion system (T2SS) pilotin, S protein 13 127 2.6E-49 T 28-03-2018 IPR016502 Type II secretion system (T2SS) pilotin, S protein A6A12_RS01160 7d987b5eecbbbb59f61f241ff27e56de 182 Gene3D G3DSA:3.30.70.940 6 119 2.9E-40 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A6A12_RS01160 7d987b5eecbbbb59f61f241ff27e56de 182 SUPERFAMILY SSF50104 125 181 4.21E-19 T 28-03-2018 IPR008991 Translation protein SH3-like domain A6A12_RS01160 7d987b5eecbbbb59f61f241ff27e56de 182 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 6 181 25.456 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A6A12_RS01160 7d987b5eecbbbb59f61f241ff27e56de 182 Gene3D G3DSA:2.30.30.30 122 181 4.2E-20 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 A6A12_RS01160 7d987b5eecbbbb59f61f241ff27e56de 182 SMART SM00739 127 154 4.8E-5 T 28-03-2018 IPR005824 KOW A6A12_RS01160 7d987b5eecbbbb59f61f241ff27e56de 182 SMART SM00738 6 115 5.0E-48 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A6A12_RS01160 7d987b5eecbbbb59f61f241ff27e56de 182 PRINTS PR00338 Transcription termination factor NUSG signature 139 154 9.4E-22 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A6A12_RS01160 7d987b5eecbbbb59f61f241ff27e56de 182 PRINTS PR00338 Transcription termination factor NUSG signature 61 73 9.4E-22 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A6A12_RS01160 7d987b5eecbbbb59f61f241ff27e56de 182 PRINTS PR00338 Transcription termination factor NUSG signature 157 173 9.4E-22 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A6A12_RS01160 7d987b5eecbbbb59f61f241ff27e56de 182 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 9 180 9.2E-70 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 A6A12_RS01160 7d987b5eecbbbb59f61f241ff27e56de 182 Pfam PF00467 KOW motif 131 160 3.7E-7 T 28-03-2018 IPR005824 KOW A6A12_RS01160 7d987b5eecbbbb59f61f241ff27e56de 182 SUPERFAMILY SSF82679 6 116 2.88E-39 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A6A12_RS01160 7d987b5eecbbbb59f61f241ff27e56de 182 Pfam PF02357 Transcription termination factor nusG 7 112 4.9E-26 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A6A12_RS01160 7d987b5eecbbbb59f61f241ff27e56de 182 ProSitePatterns PS01014 Transcription termination factor nusG signature. 164 173 - T 28-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 Gene3D G3DSA:3.50.30.20 2 151 4.4E-63 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 236 245 3.9E-11 T 28-03-2018 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 264 275 3.9E-11 T 28-03-2018 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 349 362 3.9E-11 T 28-03-2018 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 378 48.381 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 Pfam PF00117 Glutamine amidotransferase class-I 197 372 7.5E-46 T 28-03-2018 IPR017926 Glutamine amidotransferase A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 SUPERFAMILY SSF52317 153 377 9.63E-61 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 376 8.8E-148 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 281 298 2.3E-39 T 28-03-2018 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 264 280 2.3E-39 T 28-03-2018 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 233 247 2.3E-39 T 28-03-2018 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 306 317 2.3E-39 T 28-03-2018 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 194 208 2.3E-39 T 28-03-2018 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 PRINTS PR00097 Anthranilate synthase component II signature 349 362 1.2E-5 T 28-03-2018 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 PRINTS PR00097 Anthranilate synthase component II signature 264 275 1.2E-5 T 28-03-2018 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 PRINTS PR00097 Anthranilate synthase component II signature 236 245 1.2E-5 T 28-03-2018 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 SUPERFAMILY SSF52021 4 142 4.18E-58 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 Gene3D G3DSA:3.40.50.880 152 379 1.2E-65 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 SMART SM01097 3 133 2.7E-93 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS11475 cd6a02e079836a33c1c66f14e412d987 379 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 132 2.0E-52 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A6A12_RS01800 862d226dcab39944c74cc88a2816e317 268 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 9 264 54.796 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A6A12_RS01800 862d226dcab39944c74cc88a2816e317 268 SUPERFAMILY SSF53335 8 265 1.33E-79 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS01800 862d226dcab39944c74cc88a2816e317 268 SMART SM00650 25 197 1.9E-88 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A6A12_RS01800 862d226dcab39944c74cc88a2816e317 268 Pfam PF00398 Ribosomal RNA adenine dimethylase 9 264 7.8E-76 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A6A12_RS01800 862d226dcab39944c74cc88a2816e317 268 Gene3D G3DSA:3.40.50.150 2 208 2.6E-57 T 28-03-2018 A6A12_RS01800 862d226dcab39944c74cc88a2816e317 268 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 41 68 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A6A12_RS01800 862d226dcab39944c74cc88a2816e317 268 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 10 263 2.3E-86 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A6A12_RS01800 862d226dcab39944c74cc88a2816e317 268 Gene3D G3DSA:1.10.8.100 209 263 4.3E-18 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 A6A12_RS05355 03ae4e5b9b00fb09884bc598ab68df3d 303 Gene3D G3DSA:3.40.190.10 178 265 1.7E-17 T 28-03-2018 A6A12_RS05355 03ae4e5b9b00fb09884bc598ab68df3d 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS05355 03ae4e5b9b00fb09884bc598ab68df3d 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS05355 03ae4e5b9b00fb09884bc598ab68df3d 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS05355 03ae4e5b9b00fb09884bc598ab68df3d 303 SUPERFAMILY SSF53850 89 296 2.9E-39 T 28-03-2018 A6A12_RS05355 03ae4e5b9b00fb09884bc598ab68df3d 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 4.4E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS05355 03ae4e5b9b00fb09884bc598ab68df3d 303 Gene3D G3DSA:3.40.190.10 89 177 9.5E-17 T 28-03-2018 A6A12_RS05355 03ae4e5b9b00fb09884bc598ab68df3d 303 SUPERFAMILY SSF46785 1 112 1.31E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05355 03ae4e5b9b00fb09884bc598ab68df3d 303 Pfam PF03466 LysR substrate binding domain 89 293 5.3E-41 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS05355 03ae4e5b9b00fb09884bc598ab68df3d 303 Gene3D G3DSA:1.10.10.10 1 84 8.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05785 a1e11f7e2e4713f3660aca6577679c73 445 Pfam PF03882 MukF winged-helix domain 10 122 8.6E-54 T 28-03-2018 IPR033439 Chromosome partition protein MukF, winged-helix domain A6A12_RS05785 a1e11f7e2e4713f3660aca6577679c73 445 Pfam PF17193 MukF C-terminal domain 288 445 1.1E-76 T 28-03-2018 IPR033441 Chromosome partition protein MukF, C-terminal domain A6A12_RS05785 a1e11f7e2e4713f3660aca6577679c73 445 SUPERFAMILY SSF46785 13 123 2.99E-44 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05785 a1e11f7e2e4713f3660aca6577679c73 445 Hamap MF_01803 Chromosome partition protein MukF [mukF]. 6 445 54.314 T 28-03-2018 IPR005582 Chromosome partition protein MukF GO:0005509|GO:0006260|GO:0007059 A6A12_RS05785 a1e11f7e2e4713f3660aca6577679c73 445 Pfam PF17192 MukF middle domain 126 286 9.4E-80 T 28-03-2018 IPR033440 Chromosome partition protein MukF, middle domain A6A12_RS05785 a1e11f7e2e4713f3660aca6577679c73 445 PIRSF PIRSF018282 1 445 1.6E-245 T 28-03-2018 IPR005582 Chromosome partition protein MukF GO:0005509|GO:0006260|GO:0007059 A6A12_RS05785 a1e11f7e2e4713f3660aca6577679c73 445 SUPERFAMILY SSF140570 124 286 1.22E-76 T 28-03-2018 IPR033440 Chromosome partition protein MukF, middle domain A6A12_RS05785 a1e11f7e2e4713f3660aca6577679c73 445 Gene3D G3DSA:1.10.10.10 29 121 2.1E-38 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS07480 5cb2dcdfbf91890708c7528d6209aba0 221 Pfam PF11201 Protein of unknown function (DUF2982) 67 216 1.5E-60 T 28-03-2018 IPR021367 Protein of unknown function DUF2982 A6A12_RS13235 98c7020178be29a06649d7f2522f46db 723 SUPERFAMILY SSF52540 529 706 3.75E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13235 98c7020178be29a06649d7f2522f46db 723 Gene3D G3DSA:3.30.1890.10 45 427 7.0E-76 T 28-03-2018 A6A12_RS13235 98c7020178be29a06649d7f2522f46db 723 Pfam PF13807 G-rich domain on putative tyrosine kinase 371 451 8.9E-33 T 28-03-2018 IPR032807 Tyrosine kinase, G-rich domain A6A12_RS13235 98c7020178be29a06649d7f2522f46db 723 Pfam PF13614 AAA domain 539 653 1.8E-12 T 28-03-2018 IPR025669 AAA domain A6A12_RS13235 98c7020178be29a06649d7f2522f46db 723 Gene3D G3DSA:3.40.50.300 528 716 1.9E-30 T 28-03-2018 A6A12_RS13235 98c7020178be29a06649d7f2522f46db 723 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 511 714 7.6E-52 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 A6A12_RS13235 98c7020178be29a06649d7f2522f46db 723 Pfam PF02706 Chain length determinant protein 15 107 3.4E-20 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 A6A12_RS12020 20392257518e147e9716c8b6ba9dd420 149 Gene3D G3DSA:3.40.50.10110 1 147 3.8E-40 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 A6A12_RS12020 20392257518e147e9716c8b6ba9dd420 149 SUPERFAMILY SSF102400 1 145 6.8E-43 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 A6A12_RS12020 20392257518e147e9716c8b6ba9dd420 149 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 142 4.8E-34 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 Pfam PF09371 Tex-like protein N-terminal domain 9 192 1.3E-69 T 28-03-2018 IPR018974 Tex-like protein, N-terminal A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 Pfam PF16921 Tex protein YqgF-like domain 327 451 8.6E-56 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 Gene3D G3DSA:1.10.3500.10 102 354 9.4E-78 T 28-03-2018 IPR023323 Tex-like domain A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 Gene3D G3DSA:2.40.50.140 652 760 4.4E-26 T 28-03-2018 A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 Gene3D G3DSA:1.10.3500.10 355 498 1.0E-41 T 28-03-2018 IPR023323 Tex-like domain A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 Pfam PF12836 Helix-hairpin-helix motif 491 555 2.0E-28 T 28-03-2018 A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 Gene3D G3DSA:1.10.150.310 499 630 1.2E-43 T 28-03-2018 A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 Pfam PF00575 S1 RNA binding domain 648 720 9.7E-21 T 28-03-2018 IPR003029 S1 domain GO:0003676 A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 SUPERFAMILY SSF47781 560 632 6.67E-19 T 28-03-2018 IPR010994 RuvA domain 2-like A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 SUPERFAMILY SSF47781 470 557 1.67E-27 T 28-03-2018 IPR010994 RuvA domain 2-like A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 Gene3D G3DSA:1.10.10.650 2 101 1.0E-34 T 28-03-2018 IPR023319 Tex-like protein, HTH domain A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 SMART SM00316 649 720 3.7E-25 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 SUPERFAMILY SSF158832 3 321 2.09E-119 T 28-03-2018 A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 SUPERFAMILY SSF50249 637 723 2.16E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 SUPERFAMILY SSF53098 322 469 1.82E-50 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS00945 593b47821fee02f18ca3a839d0319fb9 776 SMART SM00732 326 424 6.0E-35 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 Gene3D G3DSA:1.10.601.10 2 163 8.8E-60 T 28-03-2018 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 Pfam PF00140 Sigma-70 factor, region 1.2 56 89 1.4E-11 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 118 131 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 9 328 39.736 T 28-03-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 Pfam PF04542 Sigma-70 region 2 94 163 8.0E-20 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 287 313 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 Gene3D G3DSA:1.10.10.10 164 214 3.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 90 317 5.6E-37 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 SUPERFAMILY SSF88946 56 164 1.7E-44 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 Pfam PF04545 Sigma-70, region 4 262 315 1.3E-17 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 Pfam PF04539 Sigma-70 region 3 174 247 7.3E-22 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 PRINTS PR00046 Major sigma-70 factor signature 142 150 1.5E-27 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 PRINTS PR00046 Major sigma-70 factor signature 302 313 1.5E-27 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 PRINTS PR00046 Major sigma-70 factor signature 266 278 1.5E-27 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 PRINTS PR00046 Major sigma-70 factor signature 118 131 1.5E-27 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 PRINTS PR00046 Major sigma-70 factor signature 287 302 1.5E-27 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 Gene3D G3DSA:1.10.10.10 256 325 1.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 SUPERFAMILY SSF88659 224 323 1.74E-25 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 SUPERFAMILY SSF88659 167 240 2.18E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02415 0000e7af678ffd9601fc35072a06b3b0 333 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 50 328 1.5E-139 T 28-03-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS04320 79ab3f63aed0f3ae57e8e3d78158cba2 199 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 11 185 1.1E-32 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT A6A12_RS12305 a9300e4d597a9e32b2b167c76606c36b 304 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 6 304 57.498 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A6A12_RS12305 a9300e4d597a9e32b2b167c76606c36b 304 Gene3D G3DSA:3.40.50.620 2 302 1.9E-41 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS12305 a9300e4d597a9e32b2b167c76606c36b 304 PIRSF PIRSF002936 1 304 1.3E-156 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A6A12_RS12305 a9300e4d597a9e32b2b167c76606c36b 304 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 31 259 4.1E-64 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 A6A12_RS12305 a9300e4d597a9e32b2b167c76606c36b 304 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 11 304 1.3E-162 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A6A12_RS12305 a9300e4d597a9e32b2b167c76606c36b 304 SUPERFAMILY SSF52402 8 211 2.87E-74 T 28-03-2018 A6A12_RS12310 f54fedcdbbedb5345b1f2e50f5aad2c2 292 Gene3D G3DSA:3.40.1010.10 39 164 8.2E-34 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A6A12_RS12310 f54fedcdbbedb5345b1f2e50f5aad2c2 292 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 120 153 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A6A12_RS12310 f54fedcdbbedb5345b1f2e50f5aad2c2 292 Gene3D G3DSA:3.30.950.10 165 292 2.1E-38 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A6A12_RS12310 f54fedcdbbedb5345b1f2e50f5aad2c2 292 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 45 59 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A6A12_RS12310 f54fedcdbbedb5345b1f2e50f5aad2c2 292 SUPERFAMILY SSF53790 36 280 3.01E-77 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A6A12_RS12310 f54fedcdbbedb5345b1f2e50f5aad2c2 292 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 40 273 1.2E-91 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 A6A12_RS12310 f54fedcdbbedb5345b1f2e50f5aad2c2 292 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 42 251 5.9E-45 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 1.7E-36 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 226 235 1.7E-36 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 79 88 1.7E-36 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 1.7E-36 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 1.7E-36 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 1.7E-36 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 Gene3D G3DSA:3.40.50.1370 1 147 4.8E-51 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 303 1.3E-32 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 7 307 38.102 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 4.3E-45 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 8 305 1.6E-115 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 Gene3D G3DSA:3.40.50.1370 148 308 4.4E-50 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 4.3E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 4.3E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 4.3E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 4.3E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS12065 0a72eaee998147f8487e353d1a0b7a72 309 SUPERFAMILY SSF53671 3 307 8.25E-101 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS06700 ee6ed0f5a060de2a37ecdd6fe64269ff 204 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 7 185 8.5E-82 T 28-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO A6A12_RS06700 ee6ed0f5a060de2a37ecdd6fe64269ff 204 Gene3D G3DSA:1.10.760.10 38 204 2.6E-26 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS06700 ee6ed0f5a060de2a37ecdd6fe64269ff 204 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 7 185 2.5E-81 T 28-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO A6A12_RS06700 ee6ed0f5a060de2a37ecdd6fe64269ff 204 SUPERFAMILY SSF46626 19 200 1.55E-27 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS13230 151f588e72292ba6b780ffb235793eb3 148 PIRSF PIRSF000441 6 148 6.0E-29 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 A6A12_RS13230 151f588e72292ba6b780ffb235793eb3 148 SUPERFAMILY SSF51161 14 146 3.19E-19 T 28-03-2018 IPR011004 Trimeric LpxA-like A6A12_RS13230 151f588e72292ba6b780ffb235793eb3 148 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 106 134 0.0028 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS13230 151f588e72292ba6b780ffb235793eb3 148 Gene3D G3DSA:2.160.10.10 9 147 5.7E-16 T 28-03-2018 A6A12_RS00410 b4d437e2049a2c5a278119e0c7806861 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 4.5E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A6A12_RS00410 b4d437e2049a2c5a278119e0c7806861 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 166 4.5E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A6A12_RS00410 b4d437e2049a2c5a278119e0c7806861 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 196 209 4.5E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A6A12_RS00410 b4d437e2049a2c5a278119e0c7806861 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 15 206 2.0E-10 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS00410 b4d437e2049a2c5a278119e0c7806861 237 Gene3D G3DSA:3.40.50.1000 5 227 2.1E-21 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS00410 b4d437e2049a2c5a278119e0c7806861 237 SUPERFAMILY SSF56784 9 236 6.46E-36 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS00410 b4d437e2049a2c5a278119e0c7806861 237 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 114 199 5.8E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 A6A12_RS07905 ce3da6bf6566648cf1b2e86f026d7fc9 327 Pfam PF01584 CheW-like domain 40 165 1.8E-30 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS07905 ce3da6bf6566648cf1b2e86f026d7fc9 327 Gene3D G3DSA:2.40.50.180 47 111 9.6E-16 T 28-03-2018 A6A12_RS07905 ce3da6bf6566648cf1b2e86f026d7fc9 327 PIRSF PIRSF002867 2 327 1.0E-100 T 28-03-2018 IPR024181 Chemotaxis response regulator CheV A6A12_RS07905 ce3da6bf6566648cf1b2e86f026d7fc9 327 Gene3D G3DSA:2.30.30.40 112 157 5.3E-12 T 28-03-2018 A6A12_RS07905 ce3da6bf6566648cf1b2e86f026d7fc9 327 SUPERFAMILY SSF50341 10 168 3.79E-33 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS07905 ce3da6bf6566648cf1b2e86f026d7fc9 327 SUPERFAMILY SSF52172 196 312 7.83E-28 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS07905 ce3da6bf6566648cf1b2e86f026d7fc9 327 Pfam PF00072 Response regulator receiver domain 198 318 1.1E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS07905 ce3da6bf6566648cf1b2e86f026d7fc9 327 SMART SM00448 196 321 4.1E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS07905 ce3da6bf6566648cf1b2e86f026d7fc9 327 SMART SM00260 17 163 4.6E-28 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS07905 ce3da6bf6566648cf1b2e86f026d7fc9 327 Gene3D G3DSA:3.40.50.2300 189 323 2.6E-28 T 28-03-2018 A6A12_RS03415 a80e621e595a7d8b5d633d060fd4f7fc 548 Gene3D G3DSA:1.10.3720.10 8 532 3.0E-39 T 28-03-2018 A6A12_RS03415 a80e621e595a7d8b5d633d060fd4f7fc 548 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 279 539 1.5E-75 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 A6A12_RS03415 a80e621e595a7d8b5d633d060fd4f7fc 548 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 315 467 3.9E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS03415 a80e621e595a7d8b5d633d060fd4f7fc 548 SUPERFAMILY SSF161098 260 529 1.7E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS10205 65597d3cdd32e5b9cc51e412ae97fea5 440 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 24 435 1.3E-193 T 28-03-2018 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A6A12_RS10205 65597d3cdd32e5b9cc51e412ae97fea5 440 SMART SM00382 158 342 2.2E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS10205 65597d3cdd32e5b9cc51e412ae97fea5 440 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 348 357 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A6A12_RS10205 65597d3cdd32e5b9cc51e412ae97fea5 440 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 22 437 1.5E-172 T 28-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A6A12_RS10205 65597d3cdd32e5b9cc51e412ae97fea5 440 Gene3D G3DSA:3.40.50.300 92 364 3.4E-84 T 28-03-2018 A6A12_RS10205 65597d3cdd32e5b9cc51e412ae97fea5 440 SUPERFAMILY SSF52540 93 362 4.16E-95 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS10205 65597d3cdd32e5b9cc51e412ae97fea5 440 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 146 357 5.0E-72 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A6A12_RS07360 ce835431078bf4bc13154b2fceb60c4e 453 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 2 451 5.2E-229 T 28-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A6A12_RS07360 ce835431078bf4bc13154b2fceb60c4e 453 Pfam PF03315 Serine dehydratase beta chain 3 155 2.1E-54 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 A6A12_RS07360 ce835431078bf4bc13154b2fceb60c4e 453 SUPERFAMILY SSF143548 16 157 3.14E-44 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A6A12_RS07360 ce835431078bf4bc13154b2fceb60c4e 453 Pfam PF03313 Serine dehydratase alpha chain 184 448 2.2E-98 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit A6A12_RS07360 ce835431078bf4bc13154b2fceb60c4e 453 Gene3D G3DSA:3.30.1330.90 10 158 1.1E-49 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 A6A12_RS07360 ce835431078bf4bc13154b2fceb60c4e 453 Gene3D G3DSA:1.10.4100.10 253 444 1.0E-37 T 28-03-2018 A6A12_RS14315 595609aaaba39990969b2a4fafaa4b7b 207 SUPERFAMILY SSF54980 139 204 1.41E-8 T 28-03-2018 IPR035647 EF-G domain III/V-like A6A12_RS14315 595609aaaba39990969b2a4fafaa4b7b 207 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 5 204 3.1E-66 T 28-03-2018 IPR015796 Impact family, bacterial/archaeal A6A12_RS14315 595609aaaba39990969b2a4fafaa4b7b 207 Pfam PF09186 Domain of unknown function (DUF1949) 143 196 1.9E-9 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal A6A12_RS14315 595609aaaba39990969b2a4fafaa4b7b 207 SUPERFAMILY SSF54211 5 134 1.82E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS14315 595609aaaba39990969b2a4fafaa4b7b 207 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 82 111 - T 28-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site A6A12_RS14315 595609aaaba39990969b2a4fafaa4b7b 207 Gene3D G3DSA:3.30.230.30 10 136 3.2E-36 T 28-03-2018 IPR001498 Impact, N-terminal A6A12_RS14315 595609aaaba39990969b2a4fafaa4b7b 207 Pfam PF01205 Uncharacterized protein family UPF0029 20 127 2.4E-25 T 28-03-2018 IPR001498 Impact, N-terminal A6A12_RS14315 595609aaaba39990969b2a4fafaa4b7b 207 Gene3D G3DSA:3.30.70.240 138 201 5.4E-8 T 28-03-2018 A6A12_RS10840 ee5378fae44c2491f4fb0b9fd30b8e45 203 Gene3D G3DSA:3.30.420.10 2 203 1.8E-70 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS10840 ee5378fae44c2491f4fb0b9fd30b8e45 203 SUPERFAMILY SSF53098 11 201 1.67E-69 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS10840 ee5378fae44c2491f4fb0b9fd30b8e45 203 Hamap MF_00052_B Ribonuclease HII [rnhB]. 17 196 37.496 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 A6A12_RS10840 ee5378fae44c2491f4fb0b9fd30b8e45 203 Pfam PF01351 Ribonuclease HII 19 195 5.2E-37 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain A6A12_RS06805 5e365a74d80436d177d13a54df277df9 211 SUPERFAMILY SSF46894 138 205 1.56E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS06805 5e365a74d80436d177d13a54df277df9 211 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS06805 5e365a74d80436d177d13a54df277df9 211 SMART SM00421 143 200 2.6E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS06805 5e365a74d80436d177d13a54df277df9 211 Gene3D G3DSA:3.40.50.2300 1 126 1.1E-29 T 28-03-2018 A6A12_RS06805 5e365a74d80436d177d13a54df277df9 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 200 3.7E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS06805 5e365a74d80436d177d13a54df277df9 211 SMART SM00448 2 115 1.8E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS06805 5e365a74d80436d177d13a54df277df9 211 SUPERFAMILY SSF52172 1 125 1.34E-28 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS06805 5e365a74d80436d177d13a54df277df9 211 Pfam PF00072 Response regulator receiver domain 4 116 3.4E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS06805 5e365a74d80436d177d13a54df277df9 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 4.4E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS06805 5e365a74d80436d177d13a54df277df9 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 4.4E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS06805 5e365a74d80436d177d13a54df277df9 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 4.4E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS06805 5e365a74d80436d177d13a54df277df9 211 Gene3D G3DSA:1.10.10.10 127 210 1.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03890 96d052f9e88c4143c3658549a1d78077 294 Pfam PF01513 ATP-NAD kinase 8 273 8.4E-70 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A6A12_RS03890 96d052f9e88c4143c3658549a1d78077 294 SUPERFAMILY SSF111331 8 290 7.85E-92 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain A6A12_RS03890 96d052f9e88c4143c3658549a1d78077 294 Hamap MF_00361 NAD kinase [nadK]. 6 289 33.67 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A6A12_RS03890 96d052f9e88c4143c3658549a1d78077 294 Gene3D G3DSA:3.40.50.10330 1 142 4.2E-34 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 A6A12_RS03890 96d052f9e88c4143c3658549a1d78077 294 Gene3D G3DSA:2.60.200.30 143 266 8.3E-40 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A6A12_RS05210 c34027a9952963f8a790ef41aab1eb63 621 Pfam PF13616 PPIC-type PPIASE domain 262 362 1.0E-24 T 28-03-2018 A6A12_RS05210 c34027a9952963f8a790ef41aab1eb63 621 Gene3D G3DSA:3.10.50.40 260 386 2.1E-37 T 28-03-2018 A6A12_RS05210 c34027a9952963f8a790ef41aab1eb63 621 Gene3D G3DSA:3.10.50.40 387 498 0.021 T 28-03-2018 A6A12_RS05210 c34027a9952963f8a790ef41aab1eb63 621 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 299 320 - T 28-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 A6A12_RS05210 c34027a9952963f8a790ef41aab1eb63 621 Gene3D G3DSA:1.10.4030.10 38 172 4.6E-25 T 28-03-2018 A6A12_RS05210 c34027a9952963f8a790ef41aab1eb63 621 Gene3D G3DSA:1.10.4030.10 200 247 0.016 T 28-03-2018 A6A12_RS05210 c34027a9952963f8a790ef41aab1eb63 621 SUPERFAMILY SSF109998 203 241 4.24E-36 T 28-03-2018 IPR027304 Trigger factor/SurA domain A6A12_RS05210 c34027a9952963f8a790ef41aab1eb63 621 SUPERFAMILY SSF109998 39 169 4.24E-36 T 28-03-2018 IPR027304 Trigger factor/SurA domain A6A12_RS05210 c34027a9952963f8a790ef41aab1eb63 621 SUPERFAMILY SSF54534 225 361 7.2E-28 T 28-03-2018 A6A12_RS05210 c34027a9952963f8a790ef41aab1eb63 621 Pfam PF13624 SurA N-terminal domain 1 166 8.3E-50 T 28-03-2018 A6A12_RS00820 18e854188d7858e25cad1a4735cfe649 304 PIRSF PIRSF035875 2 289 2.2E-52 T 28-03-2018 IPR017039 Virulence factor BrkB A6A12_RS00820 18e854188d7858e25cad1a4735cfe649 304 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 13 270 7.7E-81 T 28-03-2018 IPR017039 Virulence factor BrkB A6A12_RS00820 18e854188d7858e25cad1a4735cfe649 304 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 12 287 23.717 T 28-03-2018 IPR023679 Uncharacterised protein family UPF0761, bacterial A6A12_RS00820 18e854188d7858e25cad1a4735cfe649 304 Pfam PF03631 Virulence factor BrkB 24 270 1.3E-59 T 28-03-2018 IPR017039 Virulence factor BrkB A6A12_RS14400 00b394473657eabc275d4cd589f1a75b 210 Pfam PF02527 rRNA small subunit methyltransferase G 24 204 2.0E-62 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A6A12_RS14400 00b394473657eabc275d4cd589f1a75b 210 PIRSF PIRSF003078 1 209 2.9E-61 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A6A12_RS14400 00b394473657eabc275d4cd589f1a75b 210 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 29 207 1.9E-58 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A6A12_RS14400 00b394473657eabc275d4cd589f1a75b 210 Gene3D G3DSA:3.40.50.150 4 210 1.7E-36 T 28-03-2018 A6A12_RS14400 00b394473657eabc275d4cd589f1a75b 210 SUPERFAMILY SSF53335 12 208 2.05E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS14400 00b394473657eabc275d4cd589f1a75b 210 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 16 205 28.49 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 A6A12_RS01670 a31b921af65add14ac75d5aa864e4521 188 SUPERFAMILY SSF52972 1 186 2.22E-62 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A6A12_RS01670 a31b921af65add14ac75d5aa864e4521 188 Pfam PF02545 Maf-like protein 5 186 3.8E-61 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 A6A12_RS01670 a31b921af65add14ac75d5aa864e4521 188 Hamap MF_00528 Septum formation protein Maf [maf]. 5 188 29.143 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 A6A12_RS01670 a31b921af65add14ac75d5aa864e4521 188 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 184 9.3E-57 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 A6A12_RS01670 a31b921af65add14ac75d5aa864e4521 188 PIRSF PIRSF006305 1 188 4.9E-58 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 A6A12_RS01670 a31b921af65add14ac75d5aa864e4521 188 Gene3D G3DSA:3.90.950.10 2 188 5.6E-70 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A6A12_RS05740 3e65911d2d0d59b33deb345d2c27cc4f 266 Gene3D G3DSA:3.40.50.1820 6 195 2.7E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS05740 3e65911d2d0d59b33deb345d2c27cc4f 266 Pfam PF00561 alpha/beta hydrolase fold 19 121 1.0E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A6A12_RS05740 3e65911d2d0d59b33deb345d2c27cc4f 266 SUPERFAMILY SSF53474 11 263 1.45E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS05740 3e65911d2d0d59b33deb345d2c27cc4f 266 Gene3D G3DSA:3.40.50.1820 196 265 1.5E-8 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS00970 5379173bffe52208ccffdf8c55ada35f 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 6.5E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS00970 5379173bffe52208ccffdf8c55ada35f 310 Gene3D G3DSA:3.40.190.10 178 265 4.8E-25 T 28-03-2018 A6A12_RS00970 5379173bffe52208ccffdf8c55ada35f 310 Gene3D G3DSA:3.40.190.10 89 177 7.3E-14 T 28-03-2018 A6A12_RS00970 5379173bffe52208ccffdf8c55ada35f 310 SUPERFAMILY SSF46785 4 112 3.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS00970 5379173bffe52208ccffdf8c55ada35f 310 Pfam PF03466 LysR substrate binding domain 88 291 1.6E-40 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS00970 5379173bffe52208ccffdf8c55ada35f 310 SUPERFAMILY SSF53850 89 293 1.57E-41 T 28-03-2018 A6A12_RS00970 5379173bffe52208ccffdf8c55ada35f 310 Gene3D G3DSA:1.10.10.10 3 87 5.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS12925 dd80169a546c11b9356ee5272cb7b408 388 Gene3D G3DSA:3.90.1150.10 249 387 2.5E-50 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS12925 dd80169a546c11b9356ee5272cb7b408 388 Gene3D G3DSA:3.40.640.10 2 248 5.5E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS12925 dd80169a546c11b9356ee5272cb7b408 388 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 381 3.2E-134 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A6A12_RS12925 dd80169a546c11b9356ee5272cb7b408 388 TIGRFAM TIGR02080 O_succ_thio_ly: O-succinylhomoserine (thiol)-lyase 4 383 3.6E-200 T 28-03-2018 IPR011821 O-succinylhomoserine (thiol)-lyase KEGG: 00270+2.5.1.48|KEGG: 00450+2.5.1.48|KEGG: 00920+2.5.1.48|MetaCyc: PWY-801 A6A12_RS12925 dd80169a546c11b9356ee5272cb7b408 388 PIRSF PIRSF001434 1 385 1.1E-128 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A6A12_RS12925 dd80169a546c11b9356ee5272cb7b408 388 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 191 205 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A6A12_RS12925 dd80169a546c11b9356ee5272cb7b408 388 SUPERFAMILY SSF53383 9 383 2.13E-116 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS03615 79afaa0a30fb112fe32e6bf32a0e52b0 514 Pfam PF01235 Sodium:alanine symporter family 51 471 1.3E-148 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS03615 79afaa0a30fb112fe32e6bf32a0e52b0 514 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 462 4.0E-135 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS03615 79afaa0a30fb112fe32e6bf32a0e52b0 514 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 86 101 - T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS03615 79afaa0a30fb112fe32e6bf32a0e52b0 514 PRINTS PR00175 Sodium/alanine symporter signature 189 207 1.1E-56 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS03615 79afaa0a30fb112fe32e6bf32a0e52b0 514 PRINTS PR00175 Sodium/alanine symporter signature 217 236 1.1E-56 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS03615 79afaa0a30fb112fe32e6bf32a0e52b0 514 PRINTS PR00175 Sodium/alanine symporter signature 304 322 1.1E-56 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS03615 79afaa0a30fb112fe32e6bf32a0e52b0 514 PRINTS PR00175 Sodium/alanine symporter signature 86 108 1.1E-56 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS03615 79afaa0a30fb112fe32e6bf32a0e52b0 514 PRINTS PR00175 Sodium/alanine symporter signature 365 387 1.1E-56 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS03615 79afaa0a30fb112fe32e6bf32a0e52b0 514 PRINTS PR00175 Sodium/alanine symporter signature 428 448 1.1E-56 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS13720 a086b14d8f57b55ca5d3e97ab6c75498 261 SMART SM00382 26 214 5.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS13720 a086b14d8f57b55ca5d3e97ab6c75498 261 Pfam PF00005 ABC transporter 21 166 8.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS13720 a086b14d8f57b55ca5d3e97ab6c75498 261 SUPERFAMILY SSF52540 3 227 2.01E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13720 a086b14d8f57b55ca5d3e97ab6c75498 261 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS13720 a086b14d8f57b55ca5d3e97ab6c75498 261 Gene3D G3DSA:3.40.50.300 1 240 1.8E-52 T 28-03-2018 A6A12_RS05655 5e4059ca31462b7fa1eaefea7764b82d 220 PIRSF PIRSF000495 16 220 5.5E-64 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A6A12_RS05655 5e4059ca31462b7fa1eaefea7764b82d 220 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 18 219 5.8E-67 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A6A12_RS05655 5e4059ca31462b7fa1eaefea7764b82d 220 SUPERFAMILY SSF52317 16 219 1.58E-53 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS05655 5e4059ca31462b7fa1eaefea7764b82d 220 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 17 220 33.874 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 A6A12_RS05655 5e4059ca31462b7fa1eaefea7764b82d 220 Gene3D G3DSA:3.40.50.880 14 220 3.6E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS05655 5e4059ca31462b7fa1eaefea7764b82d 220 Pfam PF00117 Glutamine amidotransferase class-I 20 218 9.0E-18 T 28-03-2018 IPR017926 Glutamine amidotransferase A6A12_RS03655 422920437dd653bb56e6e3712a356a0d 374 Gene3D G3DSA:3.40.640.10 31 275 6.1E-19 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS03655 422920437dd653bb56e6e3712a356a0d 374 TIGRFAM TIGR01437 selA_rel: uncharacterized pyridoxal phosphate-dependent enzyme 4 365 3.6E-175 T 28-03-2018 IPR006337 Pyridoxal phosphate-dependent enzyme, SelA-like KEGG: 00030+4.3.1.29|MetaCyc: PWY-7310 A6A12_RS03655 422920437dd653bb56e6e3712a356a0d 374 Pfam PF03841 L-seryl-tRNA selenium transferase 13 268 1.3E-13 T 28-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 A6A12_RS03655 422920437dd653bb56e6e3712a356a0d 374 SUPERFAMILY SSF53383 6 366 1.28E-33 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS05835 305bb564b9e91a706f0a34e603ad72ad 591 Gene3D G3DSA:2.40.50.140 1 107 6.1E-26 T 28-03-2018 A6A12_RS05835 305bb564b9e91a706f0a34e603ad72ad 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 518 532 2.7E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS05835 305bb564b9e91a706f0a34e603ad72ad 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 474 490 2.7E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS05835 305bb564b9e91a706f0a34e603ad72ad 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 190 202 2.7E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS05835 305bb564b9e91a706f0a34e603ad72ad 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 2.7E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS05835 305bb564b9e91a706f0a34e603ad72ad 591 Pfam PF00152 tRNA synthetases class II (D, K and N) 117 558 4.3E-106 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS05835 305bb564b9e91a706f0a34e603ad72ad 591 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 583 6.1E-265 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 A6A12_RS05835 305bb564b9e91a706f0a34e603ad72ad 591 SUPERFAMILY SSF55261 288 418 1.34E-45 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A6A12_RS05835 305bb564b9e91a706f0a34e603ad72ad 591 SUPERFAMILY SSF55681 108 287 1.38E-101 T 28-03-2018 A6A12_RS05835 305bb564b9e91a706f0a34e603ad72ad 591 SUPERFAMILY SSF55681 420 582 1.38E-101 T 28-03-2018 A6A12_RS05835 305bb564b9e91a706f0a34e603ad72ad 591 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 584 33.388 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 A6A12_RS05835 305bb564b9e91a706f0a34e603ad72ad 591 Pfam PF02938 GAD domain 307 406 1.4E-29 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 A6A12_RS05835 305bb564b9e91a706f0a34e603ad72ad 591 Pfam PF01336 OB-fold nucleic acid binding domain 18 102 5.1E-16 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A6A12_RS05835 305bb564b9e91a706f0a34e603ad72ad 591 Gene3D G3DSA:3.30.930.10 131 586 1.8E-100 T 28-03-2018 A6A12_RS05835 305bb564b9e91a706f0a34e603ad72ad 591 SUPERFAMILY SSF50249 1 105 1.35E-33 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS02995 9d5be87597703e9aa9b57af2f2e38ed6 327 SUPERFAMILY SSF48452 56 306 1.58E-60 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS02995 9d5be87597703e9aa9b57af2f2e38ed6 327 Gene3D G3DSA:1.25.40.10 44 325 3.8E-29 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS02995 9d5be87597703e9aa9b57af2f2e38ed6 327 PIRSF PIRSF004654 20 315 7.8E-84 T 28-03-2018 IPR023605 Lipoprotein NlpI A6A12_RS02995 9d5be87597703e9aa9b57af2f2e38ed6 327 SMART SM00028 156 189 190.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS02995 9d5be87597703e9aa9b57af2f2e38ed6 327 SMART SM00028 88 121 8.4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS02995 9d5be87597703e9aa9b57af2f2e38ed6 327 SMART SM00028 259 292 23.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS02995 9d5be87597703e9aa9b57af2f2e38ed6 327 SMART SM00028 122 155 0.019 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS13940 db16752ed7a9f667959a882b25bd0429 312 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 18 69 1.5E-8 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A6A12_RS13940 db16752ed7a9f667959a882b25bd0429 312 SUPERFAMILY SSF161098 93 294 3.66E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS13940 db16752ed7a9f667959a882b25bd0429 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 309 4.8E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS13940 db16752ed7a9f667959a882b25bd0429 312 Gene3D G3DSA:1.10.3720.10 20 299 1.9E-46 T 28-03-2018 A6A12_RS08055 ce40dee9620be1aae339156f09736448 702 SUPERFAMILY SSF52540 447 692 2.07E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS08055 ce40dee9620be1aae339156f09736448 702 Pfam PF00664 ABC transporter transmembrane region 146 409 1.3E-48 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A6A12_RS08055 ce40dee9620be1aae339156f09736448 702 Gene3D G3DSA:3.90.70.10 24 120 1.7E-5 T 28-03-2018 A6A12_RS08055 ce40dee9620be1aae339156f09736448 702 Gene3D G3DSA:3.40.50.300 443 698 1.3E-74 T 28-03-2018 A6A12_RS08055 ce40dee9620be1aae339156f09736448 702 TIGRFAM TIGR01846 type_I_sec_HlyB: type I secretion system ATPase 55 692 3.8E-232 T 28-03-2018 IPR010132 ATPase, type I secretion system, HlyB GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 A6A12_RS08055 ce40dee9620be1aae339156f09736448 702 ProSitePatterns PS00211 ABC transporters family signature. 594 608 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS08055 ce40dee9620be1aae339156f09736448 702 Gene3D G3DSA:1.20.1560.10 121 442 4.8E-48 T 28-03-2018 A6A12_RS08055 ce40dee9620be1aae339156f09736448 702 Pfam PF00005 ABC transporter 474 622 1.5E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS08055 ce40dee9620be1aae339156f09736448 702 SUPERFAMILY SSF90123 130 442 1.03E-63 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A6A12_RS08055 ce40dee9620be1aae339156f09736448 702 SMART SM00382 482 668 1.2E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS02460 ddc6a26d2c1b1efdfb627d0748e8cfad 167 Pfam PF02631 RecX family 47 164 1.5E-29 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 A6A12_RS02460 ddc6a26d2c1b1efdfb627d0748e8cfad 167 Hamap MF_01114 Regulatory protein RecX [recX]. 3 167 13.583 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 A6A12_RS02460 ddc6a26d2c1b1efdfb627d0748e8cfad 167 Gene3D G3DSA:1.10.10.10 117 167 3.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS02460 ddc6a26d2c1b1efdfb627d0748e8cfad 167 Gene3D G3DSA:1.10.10.10 17 70 1.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS02460 ddc6a26d2c1b1efdfb627d0748e8cfad 167 Gene3D G3DSA:1.10.10.10 71 113 4.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09875 c1460427a5e7a7883cf876b583436c4e 162 Pfam PF10975 Protein of unknown function (DUF2802) 65 132 1.3E-22 T 28-03-2018 IPR021244 Protein of unknown function DUF2802 A6A12_RS05705 7606631ce977ae917b04eca7e6cf1706 232 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 107 225 1.4E-31 T 28-03-2018 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 A6A12_RS05705 7606631ce977ae917b04eca7e6cf1706 232 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 1 232 35.302 T 28-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 A6A12_RS05705 7606631ce977ae917b04eca7e6cf1706 232 PIRSF PIRSF037208 1 232 1.9E-80 T 28-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 A6A12_RS05705 7606631ce977ae917b04eca7e6cf1706 232 Gene3D G3DSA:3.40.630.30 78 222 3.3E-7 T 28-03-2018 A6A12_RS05705 7606631ce977ae917b04eca7e6cf1706 232 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 16 86 2.7E-17 T 28-03-2018 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 A6A12_RS05705 7606631ce977ae917b04eca7e6cf1706 232 SUPERFAMILY SSF55729 80 231 1.7E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS11020 77b64039bfbbba94d04ffa140e5ef57a 451 SUPERFAMILY SSF161070 7 450 1.27E-114 T 28-03-2018 A6A12_RS11020 77b64039bfbbba94d04ffa140e5ef57a 451 Gene3D G3DSA:1.20.58.390 43 195 0.34 T 28-03-2018 A6A12_RS11020 77b64039bfbbba94d04ffa140e5ef57a 451 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 15 36 1.8E-9 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS11020 77b64039bfbbba94d04ffa140e5ef57a 451 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 311 330 1.8E-9 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS11020 77b64039bfbbba94d04ffa140e5ef57a 451 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 44 63 1.8E-9 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS11020 77b64039bfbbba94d04ffa140e5ef57a 451 Pfam PF00209 Sodium:neurotransmitter symporter family 151 449 9.0E-26 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS11020 77b64039bfbbba94d04ffa140e5ef57a 451 Pfam PF00209 Sodium:neurotransmitter symporter family 7 133 7.0E-23 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS03265 f1d60d4f64a6b25fbc4f594a84266ee2 125 Pfam PF07238 PilZ domain 3 100 4.2E-14 T 28-03-2018 IPR009875 PilZ domain GO:0035438 A6A12_RS03265 f1d60d4f64a6b25fbc4f594a84266ee2 125 Gene3D G3DSA:2.40.10.220 1 123 1.7E-19 T 28-03-2018 A6A12_RS03265 f1d60d4f64a6b25fbc4f594a84266ee2 125 PIRSF PIRSF028141 1 120 1.9E-40 T 28-03-2018 IPR027021 Cyclic di-GMP binding protein, PA4608 type A6A12_RS03265 f1d60d4f64a6b25fbc4f594a84266ee2 125 SUPERFAMILY SSF141371 1 120 3.92E-32 T 28-03-2018 A6A12_RS14050 08af7604351c7ddf49ef3475e7c8041b 232 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 11 194 2.3E-71 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A6A12_RS14050 08af7604351c7ddf49ef3475e7c8041b 232 SUPERFAMILY SSF52540 15 205 1.04E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS14050 08af7604351c7ddf49ef3475e7c8041b 232 Gene3D G3DSA:3.40.50.300 3 212 2.0E-28 T 28-03-2018 A6A12_RS14050 08af7604351c7ddf49ef3475e7c8041b 232 Pfam PF01926 50S ribosome-binding GTPase 29 147 9.3E-20 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS14050 08af7604351c7ddf49ef3475e7c8041b 232 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 15 198 27.222 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A6A12_RS05460 d2cf3c5841a6acd45e80ad47dcff8eb1 171 Gene3D G3DSA:1.10.1740.10 4 95 4.9E-19 T 28-03-2018 A6A12_RS05460 d2cf3c5841a6acd45e80ad47dcff8eb1 171 Gene3D G3DSA:1.10.10.10 96 171 1.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05460 d2cf3c5841a6acd45e80ad47dcff8eb1 171 Pfam PF08281 Sigma-70, region 4 113 165 4.2E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS05460 d2cf3c5841a6acd45e80ad47dcff8eb1 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 169 8.6E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS05460 d2cf3c5841a6acd45e80ad47dcff8eb1 171 SUPERFAMILY SSF88946 4 105 9.42E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS05460 d2cf3c5841a6acd45e80ad47dcff8eb1 171 SUPERFAMILY SSF88659 112 170 6.11E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS05460 d2cf3c5841a6acd45e80ad47dcff8eb1 171 Pfam PF04542 Sigma-70 region 2 27 92 3.3E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS10370 567f37977e872cd39402f901792d63e4 217 Pfam PF00239 Resolvase, N terminal domain 2 144 1.0E-17 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A6A12_RS10370 567f37977e872cd39402f901792d63e4 217 SMART SM00857 1 146 2.0E-17 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A6A12_RS10370 567f37977e872cd39402f901792d63e4 217 SUPERFAMILY SSF53041 2 145 4.32E-15 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A6A12_RS10370 567f37977e872cd39402f901792d63e4 217 Gene3D G3DSA:3.40.50.1390 1 156 2.4E-20 T 28-03-2018 A6A12_RS07075 757b058f7cff1c6786c9cc93562f19f7 391 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 154 276 5.8E-11 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 A6A12_RS07075 757b058f7cff1c6786c9cc93562f19f7 391 SUPERFAMILY SSF51735 11 173 2.14E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS07075 757b058f7cff1c6786c9cc93562f19f7 391 Gene3D G3DSA:3.40.50.720 7 157 3.3E-31 T 28-03-2018 A6A12_RS07075 757b058f7cff1c6786c9cc93562f19f7 391 SUPERFAMILY SSF55347 148 311 3.27E-34 T 28-03-2018 A6A12_RS07075 757b058f7cff1c6786c9cc93562f19f7 391 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 12 142 1.3E-26 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A6A12_RS07075 757b058f7cff1c6786c9cc93562f19f7 391 Gene3D G3DSA:3.30.360.10 158 391 2.2E-40 T 28-03-2018 A6A12_RS00510 b212f67edd2c625e7ec3c1843ff16d0c 101 SUPERFAMILY SSF56349 2 77 5.0E-8 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS00510 b212f67edd2c625e7ec3c1843ff16d0c 101 Gene3D G3DSA:1.10.443.10 2 87 5.4E-12 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS00510 b212f67edd2c625e7ec3c1843ff16d0c 101 Pfam PF00589 Phage integrase family 2 66 2.6E-6 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS14115 4c78cd89509ba6e8f1809cfad669f3bd 279 Pfam PF02311 AraC-like ligand binding domain 37 135 8.8E-18 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A6A12_RS14115 4c78cd89509ba6e8f1809cfad669f3bd 279 SUPERFAMILY SSF46689 228 277 1.57E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS14115 4c78cd89509ba6e8f1809cfad669f3bd 279 Gene3D G3DSA:2.60.120.280 4 165 9.5E-24 T 28-03-2018 A6A12_RS14115 4c78cd89509ba6e8f1809cfad669f3bd 279 Gene3D G3DSA:1.10.10.60 228 279 1.2E-12 T 28-03-2018 A6A12_RS14115 4c78cd89509ba6e8f1809cfad669f3bd 279 SMART SM00342 191 274 3.7E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A6A12_RS14115 4c78cd89509ba6e8f1809cfad669f3bd 279 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 258 274 5.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A6A12_RS14115 4c78cd89509ba6e8f1809cfad669f3bd 279 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 243 258 5.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 A6A12_RS14115 4c78cd89509ba6e8f1809cfad669f3bd 279 Pfam PF12833 Helix-turn-helix domain 198 275 7.3E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A6A12_RS14115 4c78cd89509ba6e8f1809cfad669f3bd 279 Gene3D G3DSA:1.10.10.60 174 227 7.5E-12 T 28-03-2018 A6A12_RS14115 4c78cd89509ba6e8f1809cfad669f3bd 279 SUPERFAMILY SSF46689 174 224 8.51E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS14115 4c78cd89509ba6e8f1809cfad669f3bd 279 SUPERFAMILY SSF51215 5 161 5.75E-27 T 28-03-2018 A6A12_RS14350 cfcdb902dc70949ae7402b766649209c 467 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 340 349 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A6A12_RS14350 cfcdb902dc70949ae7402b766649209c 467 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 467 3.5E-246 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 A6A12_RS14350 cfcdb902dc70949ae7402b766649209c 467 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 130 349 2.9E-60 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A6A12_RS14350 cfcdb902dc70949ae7402b766649209c 467 SUPERFAMILY SSF47917 352 466 5.23E-51 T 28-03-2018 A6A12_RS14350 cfcdb902dc70949ae7402b766649209c 467 SMART SM00382 142 334 2.5E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS14350 cfcdb902dc70949ae7402b766649209c 467 SUPERFAMILY SSF52540 77 355 9.41E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS14350 cfcdb902dc70949ae7402b766649209c 467 Gene3D G3DSA:1.10.1140.10 355 465 4.1E-40 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A6A12_RS14350 cfcdb902dc70949ae7402b766649209c 467 SUPERFAMILY SSF50615 1 75 4.45E-24 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A6A12_RS14350 cfcdb902dc70949ae7402b766649209c 467 Gene3D G3DSA:3.40.50.300 76 354 1.4E-84 T 28-03-2018 A6A12_RS14350 cfcdb902dc70949ae7402b766649209c 467 Gene3D G3DSA:2.40.10.170 1 75 6.8E-29 T 28-03-2018 A6A12_RS14350 cfcdb902dc70949ae7402b766649209c 467 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 73 6.6E-19 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 A6A12_RS14350 cfcdb902dc70949ae7402b766649209c 467 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 467 55.812 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 A6A12_RS00560 a686ebd9a9bc768d4b2d866f3af21a66 106 Pfam PF00581 Rhodanese-like domain 10 98 1.0E-12 T 28-03-2018 IPR001763 Rhodanese-like domain A6A12_RS00560 a686ebd9a9bc768d4b2d866f3af21a66 106 Gene3D G3DSA:3.40.250.10 2 106 2.4E-25 T 28-03-2018 IPR001763 Rhodanese-like domain A6A12_RS00560 a686ebd9a9bc768d4b2d866f3af21a66 106 SMART SM00450 7 102 1.2E-17 T 28-03-2018 IPR001763 Rhodanese-like domain A6A12_RS00560 a686ebd9a9bc768d4b2d866f3af21a66 106 SUPERFAMILY SSF52821 1 105 1.83E-29 T 28-03-2018 IPR001763 Rhodanese-like domain A6A12_RS00560 a686ebd9a9bc768d4b2d866f3af21a66 106 Hamap MF_01009 Thiosulfate sulfurtransferase GlpE [glpE]. 2 105 32.233 T 28-03-2018 IPR023695 Thiosulfate sulfurtransferase, bacterial GO:0004792|GO:0005737 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 A6A12_RS09305 6e4704646bad5101f9d8f748deed3b46 203 Gene3D G3DSA:2.50.20.10 21 194 1.6E-17 T 28-03-2018 A6A12_RS09305 6e4704646bad5101f9d8f748deed3b46 203 SUPERFAMILY SSF89392 24 189 8.24E-18 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX A6A12_RS09305 6e4704646bad5101f9d8f748deed3b46 203 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 36 189 8.1E-9 T 28-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like A6A12_RS06000 9d4c155b67b4931d481eb23f9a7b8619 573 SUPERFAMILY SSF161098 299 538 4.39E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS06000 9d4c155b67b4931d481eb23f9a7b8619 573 Gene3D G3DSA:1.10.3720.10 284 538 3.3E-19 T 28-03-2018 A6A12_RS06000 9d4c155b67b4931d481eb23f9a7b8619 573 SUPERFAMILY SSF161098 6 274 1.31E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS06000 9d4c155b67b4931d481eb23f9a7b8619 573 Gene3D G3DSA:1.10.3720.10 2 283 1.2E-21 T 28-03-2018 A6A12_RS06460 636e03cb66d3cc5ab3580963276a4993 211 SUPERFAMILY SSF103088 62 191 8.37E-28 T 28-03-2018 IPR006665 OmpA-like domain A6A12_RS06460 636e03cb66d3cc5ab3580963276a4993 211 PRINTS PR01021 OMPA domain signature 122 137 5.7E-7 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A6A12_RS06460 636e03cb66d3cc5ab3580963276a4993 211 PRINTS PR01021 OMPA domain signature 137 153 5.7E-7 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A6A12_RS06460 636e03cb66d3cc5ab3580963276a4993 211 PRINTS PR01021 OMPA domain signature 92 114 5.7E-7 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A6A12_RS06460 636e03cb66d3cc5ab3580963276a4993 211 Gene3D G3DSA:3.30.1330.60 41 210 3.2E-27 T 28-03-2018 IPR006665 OmpA-like domain A6A12_RS06460 636e03cb66d3cc5ab3580963276a4993 211 Pfam PF00691 OmpA family 91 186 5.9E-15 T 28-03-2018 IPR006665 OmpA-like domain A6A12_RS10910 3ce487bce43b49f3ebb23ada2bf24a78 243 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 2.2E-107 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS10910 3ce487bce43b49f3ebb23ada2bf24a78 243 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A6A12_RS10910 3ce487bce43b49f3ebb23ada2bf24a78 243 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 41.332 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS10910 3ce487bce43b49f3ebb23ada2bf24a78 243 PRINTS PR00395 Ribosomal protein S2 signature 175 186 1.4E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS10910 3ce487bce43b49f3ebb23ada2bf24a78 243 PRINTS PR00395 Ribosomal protein S2 signature 196 210 1.4E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS10910 3ce487bce43b49f3ebb23ada2bf24a78 243 PRINTS PR00395 Ribosomal protein S2 signature 37 46 1.4E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS10910 3ce487bce43b49f3ebb23ada2bf24a78 243 PRINTS PR00395 Ribosomal protein S2 signature 6 24 1.4E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS10910 3ce487bce43b49f3ebb23ada2bf24a78 243 PRINTS PR00395 Ribosomal protein S2 signature 158 175 1.4E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS10910 3ce487bce43b49f3ebb23ada2bf24a78 243 PRINTS PR00395 Ribosomal protein S2 signature 87 104 1.4E-37 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS10910 3ce487bce43b49f3ebb23ada2bf24a78 243 SUPERFAMILY SSF52313 6 229 2.09E-95 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain A6A12_RS10910 3ce487bce43b49f3ebb23ada2bf24a78 243 Gene3D G3DSA:3.40.50.10490 5 241 2.5E-95 T 28-03-2018 A6A12_RS10910 3ce487bce43b49f3ebb23ada2bf24a78 243 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A6A12_RS10910 3ce487bce43b49f3ebb23ada2bf24a78 243 Pfam PF00318 Ribosomal protein S2 9 224 3.5E-94 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS10260 fa217f3380f5acfa3b9db2db3c55841a 142 Pfam PF03646 FlaG protein 39 140 3.4E-25 T 28-03-2018 IPR005186 FlaG protein A6A12_RS10260 fa217f3380f5acfa3b9db2db3c55841a 142 SUPERFAMILY SSF160214 49 139 3.14E-22 T 28-03-2018 IPR005186 FlaG protein A6A12_RS10260 fa217f3380f5acfa3b9db2db3c55841a 142 Gene3D G3DSA:3.30.160.170 22 139 1.7E-22 T 28-03-2018 IPR005186 FlaG protein A6A12_RS03040 4159e0d295a3e2299f36dbd5d55947db 148 Pfam PF00583 Acetyltransferase (GNAT) family 25 121 6.5E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A6A12_RS03040 4159e0d295a3e2299f36dbd5d55947db 148 Gene3D G3DSA:3.40.630.30 3 147 1.5E-28 T 28-03-2018 A6A12_RS03040 4159e0d295a3e2299f36dbd5d55947db 148 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 13 143 4.4E-38 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 A6A12_RS03040 4159e0d295a3e2299f36dbd5d55947db 148 SUPERFAMILY SSF55729 1 145 7.09E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS02625 f3d4f4aa78d4d21d26cec8fbce8e29c3 172 SUPERFAMILY SSF52218 1 165 3.67E-50 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS02625 f3d4f4aa78d4d21d26cec8fbce8e29c3 172 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 A6A12_RS02625 f3d4f4aa78d4d21d26cec8fbce8e29c3 172 Pfam PF00258 Flavodoxin 5 160 2.7E-26 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 A6A12_RS02625 f3d4f4aa78d4d21d26cec8fbce8e29c3 172 TIGRFAM TIGR01752 flav_long: flavodoxin 2 167 5.0E-68 T 28-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 A6A12_RS02625 f3d4f4aa78d4d21d26cec8fbce8e29c3 172 PIRSF PIRSF038996 1 171 3.2E-57 T 28-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 A6A12_RS02625 f3d4f4aa78d4d21d26cec8fbce8e29c3 172 Gene3D G3DSA:3.40.50.360 77 172 2.2E-18 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS02625 f3d4f4aa78d4d21d26cec8fbce8e29c3 172 Gene3D G3DSA:3.40.50.360 1 76 1.5E-14 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS01350 6498c882ff02ad56d3fe0d49fddbc562 118 Gene3D G3DSA:3.40.1260.10 2 118 2.4E-22 T 28-03-2018 A6A12_RS01350 6498c882ff02ad56d3fe0d49fddbc562 118 TIGRFAM TIGR03010 sulf_tusC_dsrF: sulfur relay protein TusC/DsrF 3 118 1.4E-42 T 28-03-2018 IPR017462 Sulphur relay, TusC/DsrF A6A12_RS01350 6498c882ff02ad56d3fe0d49fddbc562 118 SUPERFAMILY SSF75169 1 118 1.61E-33 T 28-03-2018 IPR027396 DsrEFH-like A6A12_RS01350 6498c882ff02ad56d3fe0d49fddbc562 118 Pfam PF02635 DsrE/DsrF-like family 2 118 8.1E-26 T 28-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein A6A12_RS04115 7f6488c60de0132eaaf5568466c23f63 281 Gene3D G3DSA:3.30.1130.10 143 281 8.7E-53 T 28-03-2018 A6A12_RS04115 7f6488c60de0132eaaf5568466c23f63 281 Gene3D G3DSA:3.30.1130.10 21 135 8.6E-42 T 28-03-2018 A6A12_RS04115 7f6488c60de0132eaaf5568466c23f63 281 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 21 130 2.6E-48 T 28-03-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A6A12_RS04115 7f6488c60de0132eaaf5568466c23f63 281 PIRSF PIRSF004750 6 281 6.1E-130 T 28-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A6A12_RS04115 7f6488c60de0132eaaf5568466c23f63 281 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 281 161.749 T 28-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A6A12_RS04115 7f6488c60de0132eaaf5568466c23f63 281 TIGRFAM TIGR03138 QueF: queuine synthase 11 281 7.4E-130 T 28-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A6A12_RS04115 7f6488c60de0132eaaf5568466c23f63 281 Pfam PF14489 QueF-like protein 194 270 3.5E-28 T 28-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 A6A12_RS04115 7f6488c60de0132eaaf5568466c23f63 281 SUPERFAMILY SSF55620 184 267 2.22E-9 T 28-03-2018 A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 SMART SM00421 523 580 9.4E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 SUPERFAMILY SSF46894 517 580 7.48E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 SUPERFAMILY SSF141868 140 384 4.71E-71 T 28-03-2018 IPR001633 EAL domain A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 ProSitePatterns PS00622 LuxR-type HTH domain signature. 540 567 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 Pfam PF00563 EAL domain 141 370 1.7E-64 T 28-03-2018 IPR001633 EAL domain A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 526 540 1.8E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 556 568 1.8E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 540 556 1.8E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 Gene3D G3DSA:1.10.10.10 517 589 1.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 SMART SM00448 1 118 9.6E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 Gene3D G3DSA:3.20.20.450 131 382 2.4E-72 T 28-03-2018 IPR001633 EAL domain A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 SUPERFAMILY SSF52172 399 490 7.26E-6 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 Pfam PF00072 Response regulator receiver domain 3 118 2.5E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 Gene3D G3DSA:3.40.50.2300 1 130 1.7E-26 T 28-03-2018 A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 SUPERFAMILY SSF52172 1 122 1.57E-25 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 Pfam PF00196 Bacterial regulatory proteins, luxR family 525 579 6.4E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 SMART SM00052 134 375 7.3E-67 T 28-03-2018 IPR001633 EAL domain A6A12_RS09225 f3c6bcffbbfa23a10898a3039262af0f 592 Gene3D G3DSA:3.40.50.2300 383 503 5.2E-7 T 28-03-2018 A6A12_RS02690 340a504a85e61ae9bd7a58755fe2757e 256 Pfam PF01061 ABC-2 type transporter 8 218 5.5E-40 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A6A12_RS02690 340a504a85e61ae9bd7a58755fe2757e 256 PIRSF PIRSF006648 7 253 8.7E-26 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A6A12_RS02690 340a504a85e61ae9bd7a58755fe2757e 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 58 80 3.4E-8 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A6A12_RS02690 340a504a85e61ae9bd7a58755fe2757e 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 196 215 3.4E-8 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A6A12_RS02690 340a504a85e61ae9bd7a58755fe2757e 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 102 127 3.4E-8 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A6A12_RS02690 340a504a85e61ae9bd7a58755fe2757e 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 176 195 3.4E-8 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 A6A12_RS02930 1e57c2904985f48f270921f69de158bd 649 Pfam PF01434 Peptidase family M41 386 595 7.0E-81 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 A6A12_RS02930 1e57c2904985f48f270921f69de158bd 649 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 105 597 5.0E-241 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 A6A12_RS02930 1e57c2904985f48f270921f69de158bd 649 SMART SM00382 188 327 3.1E-26 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS02930 1e57c2904985f48f270921f69de158bd 649 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 624 37.17 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 A6A12_RS02930 1e57c2904985f48f270921f69de158bd 649 Pfam PF06480 FtsH Extracellular 8 96 1.1E-12 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 A6A12_RS02930 1e57c2904985f48f270921f69de158bd 649 SUPERFAMILY SSF52540 147 395 3.27E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS02930 1e57c2904985f48f270921f69de158bd 649 Gene3D G3DSA:3.40.50.300 132 335 2.1E-62 T 28-03-2018 A6A12_RS02930 1e57c2904985f48f270921f69de158bd 649 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 192 324 3.0E-46 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A6A12_RS02930 1e57c2904985f48f270921f69de158bd 649 SUPERFAMILY SSF140990 406 601 6.15E-75 T 28-03-2018 A6A12_RS02930 1e57c2904985f48f270921f69de158bd 649 Gene3D G3DSA:1.10.8.60 336 418 5.8E-23 T 28-03-2018 A6A12_RS02930 1e57c2904985f48f270921f69de158bd 649 ProSitePatterns PS00674 AAA-protein family signature. 295 313 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A6A12_RS13355 928ab11c349c4af971b31180c6dbd5b3 437 Gene3D G3DSA:3.40.640.10 1 298 2.7E-55 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS13355 928ab11c349c4af971b31180c6dbd5b3 437 SUPERFAMILY SSF53383 38 433 3.38E-103 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS13355 928ab11c349c4af971b31180c6dbd5b3 437 Gene3D G3DSA:3.90.1150.10 299 436 3.3E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS13355 928ab11c349c4af971b31180c6dbd5b3 437 PIRSF PIRSF000390 20 437 5.0E-123 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A6A12_RS13355 928ab11c349c4af971b31180c6dbd5b3 437 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 44 429 2.3E-113 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A6A12_RS09130 d243d243fb0ea5746a3b4164bf2ffdc5 350 SUPERFAMILY SSF102114 5 310 1.1E-89 T 28-03-2018 A6A12_RS09130 d243d243fb0ea5746a3b4164bf2ffdc5 350 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 220 310 9.6E-21 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A6A12_RS09130 d243d243fb0ea5746a3b4164bf2ffdc5 350 Pfam PF04055 Radical SAM superfamily 50 199 2.8E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A6A12_RS09130 d243d243fb0ea5746a3b4164bf2ffdc5 350 SMART SM00876 220 312 3.9E-46 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A6A12_RS09130 d243d243fb0ea5746a3b4164bf2ffdc5 350 Hamap MF_01694 Biotin synthase [bioB]. 5 313 41.523 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A6A12_RS09130 d243d243fb0ea5746a3b4164bf2ffdc5 350 SMART SM00729 43 255 2.3E-39 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A6A12_RS09130 d243d243fb0ea5746a3b4164bf2ffdc5 350 Gene3D G3DSA:3.20.20.70 4 315 2.3E-58 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS09130 d243d243fb0ea5746a3b4164bf2ffdc5 350 TIGRFAM TIGR00433 bioB: biotin synthase 15 310 4.0E-125 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A6A12_RS09130 d243d243fb0ea5746a3b4164bf2ffdc5 350 PIRSF PIRSF001619 1 319 1.2E-137 T 28-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 5.5E-10 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 72 90 5.5E-10 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 Gene3D G3DSA:3.30.300.20 381 463 4.0E-26 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 SUPERFAMILY SSF52540 139 168 3.28E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 SUPERFAMILY SSF52540 204 468 3.28E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 SUPERFAMILY SSF52540 4 168 2.72E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 462 1.1E-177 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 382 461 3.1E-24 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 SMART SM00382 205 348 0.18 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 SMART SM00382 1 173 1.8 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 Gene3D G3DSA:1.20.120.430 2 66 5.7E-15 T 28-03-2018 A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 Pfam PF01926 50S ribosome-binding GTPase 209 326 4.3E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 Pfam PF01926 50S ribosome-binding GTPase 5 119 5.2E-27 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 154 2.7E-20 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 205 371 9.0E-25 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 PIRSF PIRSF006485 1 470 1.1E-178 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 Gene3D G3DSA:3.40.50.300 254 380 7.4E-23 T 28-03-2018 A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 Hamap MF_00195 GTPase Der [der]. 2 465 38.75 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 A6A12_RS03575 c066e5cec67d6f16e9fe5ef1d7c69622 495 Gene3D G3DSA:1.20.120.430 67 253 5.6E-40 T 28-03-2018 A6A12_RS13575 cb99ff71596331b4e999aa48dd10e21b 658 Gene3D G3DSA:3.40.50.300 137 579 2.1E-46 T 28-03-2018 A6A12_RS13575 cb99ff71596331b4e999aa48dd10e21b 658 SUPERFAMILY SSF52540 175 575 6.13E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13575 cb99ff71596331b4e999aa48dd10e21b 658 Pfam PF10412 Type IV secretion-system coupling protein DNA-binding domain 174 563 2.5E-116 T 28-03-2018 IPR019476 Type IV secretion system coupling protein TraD, DNA-binding domain A6A12_RS07595 c0375d71cdc91348718c7a7fb0e3f5d2 328 Pfam PF13377 Periplasmic binding protein-like domain 170 327 1.3E-26 T 28-03-2018 A6A12_RS07595 c0375d71cdc91348718c7a7fb0e3f5d2 328 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 A6A12_RS07595 c0375d71cdc91348718c7a7fb0e3f5d2 328 Gene3D G3DSA:3.40.50.2300 175 327 3.2E-32 T 28-03-2018 A6A12_RS07595 c0375d71cdc91348718c7a7fb0e3f5d2 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 3.6E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS07595 c0375d71cdc91348718c7a7fb0e3f5d2 328 Gene3D G3DSA:1.10.260.40 3 57 2.9E-19 T 28-03-2018 A6A12_RS07595 c0375d71cdc91348718c7a7fb0e3f5d2 328 SUPERFAMILY SSF47413 2 60 8.04E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS07595 c0375d71cdc91348718c7a7fb0e3f5d2 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 5.3E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS07595 c0375d71cdc91348718c7a7fb0e3f5d2 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 5.3E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS07595 c0375d71cdc91348718c7a7fb0e3f5d2 328 Gene3D G3DSA:3.40.50.2300 58 174 4.0E-29 T 28-03-2018 A6A12_RS07595 c0375d71cdc91348718c7a7fb0e3f5d2 328 SMART SM00354 1 71 6.6E-31 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS07595 c0375d71cdc91348718c7a7fb0e3f5d2 328 SUPERFAMILY SSF53822 58 318 5.5E-58 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A6A12_RS11125 3b04c43ae06414e531c0b997fbaaa139 296 SUPERFAMILY SSF51735 1 166 2.63E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS11125 3b04c43ae06414e531c0b997fbaaa139 296 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 142 3.1E-28 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 A6A12_RS11125 3b04c43ae06414e531c0b997fbaaa139 296 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 168 290 1.5E-35 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 A6A12_RS11125 3b04c43ae06414e531c0b997fbaaa139 296 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 291 5.1E-81 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 A6A12_RS11125 3b04c43ae06414e531c0b997fbaaa139 296 SUPERFAMILY SSF48179 168 290 6.12E-33 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A6A12_RS11125 3b04c43ae06414e531c0b997fbaaa139 296 Gene3D G3DSA:1.10.1040.10 167 296 1.2E-34 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A6A12_RS11125 3b04c43ae06414e531c0b997fbaaa139 296 Gene3D G3DSA:3.40.50.720 1 166 3.4E-23 T 28-03-2018 A6A12_RS11640 c5a6ece0fad7f13ddda87f8d3794d1cb 368 SUPERFAMILY SSF52540 62 201 2.48E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11640 c5a6ece0fad7f13ddda87f8d3794d1cb 368 Gene3D G3DSA:3.40.50.300 18 364 9.5E-14 T 28-03-2018 A6A12_RS11640 c5a6ece0fad7f13ddda87f8d3794d1cb 368 Hamap MF_01919 Cell division protein ZapE [zapE]. 1 368 53.274 T 28-03-2018 IPR030870 Cell division protein ZapE GO:0016887|GO:0051301 A6A12_RS11640 c5a6ece0fad7f13ddda87f8d3794d1cb 368 Pfam PF03969 AFG1-like ATPase 1 365 1.8E-158 T 28-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 SUPERFAMILY SSF55424 354 472 8.08E-25 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 Gene3D G3DSA:3.30.390.30 353 471 9.0E-23 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 283 3.5E-19 T 28-03-2018 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 319 3.5E-19 T 28-03-2018 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.5E-19 T 28-03-2018 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 3.5E-19 T 28-03-2018 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 3.5E-19 T 28-03-2018 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 PIRSF PIRSF000350 1 472 1.5E-60 T 28-03-2018 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 Gene3D G3DSA:3.50.50.60 1 163 1.6E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 355 464 4.2E-16 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 SUPERFAMILY SSF51905 1 56 4.36E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 SUPERFAMILY SSF51905 103 191 4.36E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 SUPERFAMILY SSF51905 225 371 4.36E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 Gene3D G3DSA:3.50.50.60 167 351 7.2E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 1.5E-40 T 28-03-2018 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 1.5E-40 T 28-03-2018 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 349 370 1.5E-40 T 28-03-2018 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 439 459 1.5E-40 T 28-03-2018 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 282 1.5E-40 T 28-03-2018 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 432 1.5E-40 T 28-03-2018 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.5E-40 T 28-03-2018 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 312 319 1.5E-40 T 28-03-2018 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.5E-40 T 28-03-2018 A6A12_RS12725 abf49ca754767916dddf819a22551609 489 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 332 1.5E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS12675 a25f81b0db2aeab767f19bede869d582 362 Pfam PF01761 3-dehydroquinate synthase 68 325 1.1E-112 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A6A12_RS12675 a25f81b0db2aeab767f19bede869d582 362 Gene3D G3DSA:1.20.1090.10 173 362 1.1E-69 T 28-03-2018 A6A12_RS12675 a25f81b0db2aeab767f19bede869d582 362 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 358 43.198 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A6A12_RS12675 a25f81b0db2aeab767f19bede869d582 362 PIRSF PIRSF001455 9 359 1.0E-109 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A6A12_RS12675 a25f81b0db2aeab767f19bede869d582 362 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 354 2.0E-120 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 A6A12_RS12675 a25f81b0db2aeab767f19bede869d582 362 SUPERFAMILY SSF56796 4 356 3.53E-116 T 28-03-2018 A6A12_RS12675 a25f81b0db2aeab767f19bede869d582 362 Gene3D G3DSA:3.40.50.1970 3 172 3.9E-49 T 28-03-2018 A6A12_RS06785 879c60c2b5cefc3e41a519643e2eb330 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 146 160 7.2E-85 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06785 879c60c2b5cefc3e41a519643e2eb330 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 290 316 7.2E-85 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06785 879c60c2b5cefc3e41a519643e2eb330 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 201 220 7.2E-85 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06785 879c60c2b5cefc3e41a519643e2eb330 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 245 264 7.2E-85 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06785 879c60c2b5cefc3e41a519643e2eb330 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 46 67 7.2E-85 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06785 879c60c2b5cefc3e41a519643e2eb330 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 120 136 7.2E-85 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06785 879c60c2b5cefc3e41a519643e2eb330 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 89 102 7.2E-85 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06785 879c60c2b5cefc3e41a519643e2eb330 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 73 87 7.2E-85 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06785 879c60c2b5cefc3e41a519643e2eb330 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 30 46 7.2E-85 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06785 879c60c2b5cefc3e41a519643e2eb330 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 164 183 7.2E-85 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06785 879c60c2b5cefc3e41a519643e2eb330 345 Gene3D G3DSA:3.40.190.10 143 297 1.7E-39 T 28-03-2018 A6A12_RS06785 879c60c2b5cefc3e41a519643e2eb330 345 Gene3D G3DSA:3.40.190.10 23 142 1.4E-14 T 28-03-2018 A6A12_RS06785 879c60c2b5cefc3e41a519643e2eb330 345 SUPERFAMILY SSF53850 24 342 5.43E-94 T 28-03-2018 A6A12_RS06785 879c60c2b5cefc3e41a519643e2eb330 345 PIRSF PIRSF019574 1 345 1.8E-123 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06785 879c60c2b5cefc3e41a519643e2eb330 345 Pfam PF13416 Bacterial extracellular solute-binding protein 40 311 5.7E-43 T 28-03-2018 A6A12_RS07280 d92a34db06c29fde56c385fd8e8e17fa 445 SMART SM00387 329 440 1.6E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS07280 d92a34db06c29fde56c385fd8e8e17fa 445 Pfam PF00027 Cyclic nucleotide-binding domain 22 100 3.2E-8 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A6A12_RS07280 d92a34db06c29fde56c385fd8e8e17fa 445 SUPERFAMILY SSF55874 293 440 1.7E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS07280 d92a34db06c29fde56c385fd8e8e17fa 445 Gene3D G3DSA:3.30.565.10 290 445 1.5E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS07280 d92a34db06c29fde56c385fd8e8e17fa 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 382 2.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS07280 d92a34db06c29fde56c385fd8e8e17fa 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 396 2.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS07280 d92a34db06c29fde56c385fd8e8e17fa 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 437 2.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS07280 d92a34db06c29fde56c385fd8e8e17fa 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 419 2.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS07280 d92a34db06c29fde56c385fd8e8e17fa 445 Gene3D G3DSA:2.60.120.10 10 134 5.9E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS07280 d92a34db06c29fde56c385fd8e8e17fa 445 SUPERFAMILY SSF51206 20 131 3.93E-13 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like A6A12_RS07280 d92a34db06c29fde56c385fd8e8e17fa 445 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 330 439 2.6E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 SUPERFAMILY SSF50677 226 414 3.14E-56 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 Gene3D G3DSA:3.40.50.620 1 228 3.0E-80 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 5.0E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 PRINTS PR00985 Leucyl-tRNA synthetase signature 484 502 5.0E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 5.0E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 PRINTS PR00985 Leucyl-tRNA synthetase signature 522 544 5.0E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 PRINTS PR00985 Leucyl-tRNA synthetase signature 555 565 5.0E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 5.0E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 5.0E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 Pfam PF08264 Anticodon-binding domain of tRNA 699 819 1.7E-15 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 856 0.0 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 Gene3D G3DSA:3.90.740.10 229 415 1.1E-53 T 28-03-2018 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 403 1.6E-76 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 SUPERFAMILY SSF52374 4 226 1.15E-146 T 28-03-2018 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 SUPERFAMILY SSF52374 415 666 1.15E-146 T 28-03-2018 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 SUPERFAMILY SSF47323 660 856 5.05E-35 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 617 649 1.7E-7 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 172 2.5E-26 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 417 570 8.2E-9 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 856 23.303 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 A6A12_RS04390 2531a5cb7f9f290cc98968936afcd490 857 Gene3D G3DSA:1.10.730.10 550 856 3.0E-55 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS03075 121121087f94eeac35f4bfa420f3923b 510 Pfam PF01336 OB-fold nucleic acid binding domain 73 145 4.3E-8 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A6A12_RS03075 121121087f94eeac35f4bfa420f3923b 510 SUPERFAMILY SSF50249 16 154 1.05E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS03075 121121087f94eeac35f4bfa420f3923b 510 Gene3D G3DSA:3.30.930.10 155 506 6.3E-98 T 28-03-2018 A6A12_RS03075 121121087f94eeac35f4bfa420f3923b 510 SUPERFAMILY SSF55681 161 507 1.53E-116 T 28-03-2018 A6A12_RS03075 121121087f94eeac35f4bfa420f3923b 510 PRINTS PR00982 Lysyl-tRNA synthetase signature 391 407 8.1E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A6A12_RS03075 121121087f94eeac35f4bfa420f3923b 510 PRINTS PR00982 Lysyl-tRNA synthetase signature 243 256 8.1E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A6A12_RS03075 121121087f94eeac35f4bfa420f3923b 510 PRINTS PR00982 Lysyl-tRNA synthetase signature 214 230 8.1E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A6A12_RS03075 121121087f94eeac35f4bfa420f3923b 510 PRINTS PR00982 Lysyl-tRNA synthetase signature 198 208 8.1E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A6A12_RS03075 121121087f94eeac35f4bfa420f3923b 510 PRINTS PR00982 Lysyl-tRNA synthetase signature 261 278 8.1E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A6A12_RS03075 121121087f94eeac35f4bfa420f3923b 510 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 24 509 43.145 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A6A12_RS03075 121121087f94eeac35f4bfa420f3923b 510 Gene3D G3DSA:2.40.50.140 18 153 3.8E-27 T 28-03-2018 A6A12_RS03075 121121087f94eeac35f4bfa420f3923b 510 Pfam PF00152 tRNA synthetases class II (D, K and N) 161 506 1.4E-79 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS03075 121121087f94eeac35f4bfa420f3923b 510 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 19 509 3.3E-201 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A6A12_RS03115 a4f7eed582bc97c904196ad9bd97cb08 267 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 257 7.0E-84 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A6A12_RS03115 a4f7eed582bc97c904196ad9bd97cb08 267 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 10 262 20.494 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A6A12_RS03115 a4f7eed582bc97c904196ad9bd97cb08 267 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 6 265 1.9E-94 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A6A12_RS03115 a4f7eed582bc97c904196ad9bd97cb08 267 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 142 154 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 A6A12_RS12325 38133063d6546d0952184eb9383c2f57 377 Gene3D G3DSA:3.30.470.20 84 353 1.0E-8 T 28-03-2018 A6A12_RS12325 38133063d6546d0952184eb9383c2f57 377 SUPERFAMILY SSF56059 118 202 7.63E-8 T 28-03-2018 A6A12_RS12565 d7e3f7025411379cc6ee4cc1f3d9c360 639 SUPERFAMILY SSF52540 119 255 3.48E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12565 d7e3f7025411379cc6ee4cc1f3d9c360 639 SUPERFAMILY SSF52540 2 92 3.48E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12565 d7e3f7025411379cc6ee4cc1f3d9c360 639 SUPERFAMILY SSF52540 277 494 3.28E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12565 d7e3f7025411379cc6ee4cc1f3d9c360 639 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS12565 d7e3f7025411379cc6ee4cc1f3d9c360 639 Pfam PF12848 ABC transporter 217 295 7.2E-27 T 28-03-2018 IPR032781 ABC-transporter extension domain A6A12_RS12565 d7e3f7025411379cc6ee4cc1f3d9c360 639 Gene3D G3DSA:3.40.50.300 308 630 1.8E-48 T 28-03-2018 A6A12_RS12565 d7e3f7025411379cc6ee4cc1f3d9c360 639 Pfam PF00005 ABC transporter 17 178 2.7E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS12565 d7e3f7025411379cc6ee4cc1f3d9c360 639 Pfam PF00005 ABC transporter 328 459 7.0E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS12565 d7e3f7025411379cc6ee4cc1f3d9c360 639 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS12565 d7e3f7025411379cc6ee4cc1f3d9c360 639 Gene3D G3DSA:3.40.50.300 2 279 2.9E-48 T 28-03-2018 A6A12_RS12565 d7e3f7025411379cc6ee4cc1f3d9c360 639 SMART SM00382 26 223 4.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS12565 d7e3f7025411379cc6ee4cc1f3d9c360 639 SMART SM00382 337 503 3.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS00085 a62dab97ce81e553a01ac281d9b4e524 512 SUPERFAMILY SSF55021 335 421 3.51E-27 T 28-03-2018 A6A12_RS00085 a62dab97ce81e553a01ac281d9b4e524 512 Gene3D G3DSA:3.40.50.1100 147 327 2.8E-51 T 28-03-2018 A6A12_RS00085 a62dab97ce81e553a01ac281d9b4e524 512 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 327 417 3.1E-25 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A6A12_RS00085 a62dab97ce81e553a01ac281d9b4e524 512 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 425 511 2.8E-26 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A6A12_RS00085 a62dab97ce81e553a01ac281d9b4e524 512 Gene3D G3DSA:3.40.50.1100 36 146 4.4E-32 T 28-03-2018 A6A12_RS00085 a62dab97ce81e553a01ac281d9b4e524 512 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 13 511 3.1E-249 T 28-03-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 A6A12_RS00085 a62dab97ce81e553a01ac281d9b4e524 512 SUPERFAMILY SSF55021 418 511 2.75E-26 T 28-03-2018 A6A12_RS00085 a62dab97ce81e553a01ac281d9b4e524 512 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 314 4.2E-81 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A6A12_RS00085 a62dab97ce81e553a01ac281d9b4e524 512 Gene3D G3DSA:3.40.1020.10 336 512 7.1E-73 T 28-03-2018 A6A12_RS00085 a62dab97ce81e553a01ac281d9b4e524 512 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 51 64 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A6A12_RS00085 a62dab97ce81e553a01ac281d9b4e524 512 SUPERFAMILY SSF53686 12 363 4.58E-104 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A6A12_RS03300 e9de8bb7f00d96cb2f759ce81433605f 392 SUPERFAMILY SSF48600 7 95 1.03E-18 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A6A12_RS03300 e9de8bb7f00d96cb2f759ce81433605f 392 SMART SM00830 12 93 2.8E-21 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A6A12_RS03300 e9de8bb7f00d96cb2f759ce81433605f 392 PIRSF PIRSF001500 1 384 8.7E-141 T 28-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A6A12_RS03300 e9de8bb7f00d96cb2f759ce81433605f 392 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 329 336 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A6A12_RS03300 e9de8bb7f00d96cb2f759ce81433605f 392 Pfam PF01817 Chorismate mutase type II 12 91 3.6E-16 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A6A12_RS03300 e9de8bb7f00d96cb2f759ce81433605f 392 Pfam PF00800 Prephenate dehydratase 110 291 1.0E-59 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A6A12_RS03300 e9de8bb7f00d96cb2f759ce81433605f 392 SUPERFAMILY SSF53850 109 295 8.79E-55 T 28-03-2018 A6A12_RS03300 e9de8bb7f00d96cb2f759ce81433605f 392 Gene3D G3DSA:1.20.59.10 1 116 6.1E-26 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A6A12_RS03300 e9de8bb7f00d96cb2f759ce81433605f 392 Gene3D G3DSA:3.40.190.10 202 278 1.8E-22 T 28-03-2018 A6A12_RS03300 e9de8bb7f00d96cb2f759ce81433605f 392 SUPERFAMILY SSF55021 284 381 5.3E-26 T 28-03-2018 A6A12_RS03300 e9de8bb7f00d96cb2f759ce81433605f 392 TIGRFAM TIGR01797 CM_P_1: chorismate mutase 9 91 1.8E-27 T 28-03-2018 IPR010952 Chorismate mutase, gammaproteobacteria GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 A6A12_RS03300 e9de8bb7f00d96cb2f759ce81433605f 392 Gene3D G3DSA:3.30.70.260 293 388 1.8E-26 T 28-03-2018 A6A12_RS03300 e9de8bb7f00d96cb2f759ce81433605f 392 Gene3D G3DSA:3.40.190.10 117 201 6.9E-31 T 28-03-2018 A6A12_RS03300 e9de8bb7f00d96cb2f759ce81433605f 392 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 265 287 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 A6A12_RS05680 62c2b4bccfed0f6a643edf2709db1516 741 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 1 740 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 A6A12_RS05680 62c2b4bccfed0f6a643edf2709db1516 741 Gene3D G3DSA:3.40.718.10 56 367 3.4E-43 T 28-03-2018 A6A12_RS05680 62c2b4bccfed0f6a643edf2709db1516 741 Gene3D G3DSA:3.40.718.10 442 713 8.4E-41 T 28-03-2018 A6A12_RS05680 62c2b4bccfed0f6a643edf2709db1516 741 SUPERFAMILY SSF53659 5 740 0.0 T 28-03-2018 A6A12_RS05680 62c2b4bccfed0f6a643edf2709db1516 741 PIRSF PIRSF009407 1 741 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 A6A12_RS05680 62c2b4bccfed0f6a643edf2709db1516 741 Pfam PF03971 Monomeric isocitrate dehydrogenase 7 739 0.0 T 28-03-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 A6A12_RS10025 a38fdcde6dfbcf168e08e077beaa4164 115 SUPERFAMILY SSF81343 4 114 1.54E-26 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS10025 a38fdcde6dfbcf168e08e077beaa4164 115 Gene3D G3DSA:1.20.1300.10 1 115 2.7E-17 T 28-03-2018 A6A12_RS10025 a38fdcde6dfbcf168e08e077beaa4164 115 PIRSF PIRSF000169 1 115 2.7E-38 T 28-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 A6A12_RS10025 a38fdcde6dfbcf168e08e077beaa4164 115 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 10 113 1.9E-34 T 28-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 A6A12_RS10025 a38fdcde6dfbcf168e08e077beaa4164 115 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 10 102 2.0E-6 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS04505 316afe5cb631200400b3acbddf4f1ef3 201 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 17 178 7.7E-31 T 28-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A6A12_RS04505 316afe5cb631200400b3acbddf4f1ef3 201 Gene3D G3DSA:3.60.21.10 16 179 3.3E-28 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A6A12_RS04505 316afe5cb631200400b3acbddf4f1ef3 201 ProSitePatterns PS01269 Uncharacterized protein family UPF0025 signature. 137 161 - T 28-03-2018 IPR020935 Phosphodiesterase YfcE, conserved site A6A12_RS04505 316afe5cb631200400b3acbddf4f1ef3 201 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 17 177 2.9E-26 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A6A12_RS04505 316afe5cb631200400b3acbddf4f1ef3 201 SUPERFAMILY SSF56300 15 178 3.04E-39 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 122 133 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 Gene3D G3DSA:1.10.730.10 442 578 2.1E-47 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 3 578 1.0E-200 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 578 27.934 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 SMART SM01016 5 87 1.0E-27 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 7 87 1.6E-19 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 SUPERFAMILY SSF55190 2 106 7.06E-22 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 Pfam PF00750 tRNA synthetases class I (R) 100 448 8.6E-161 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 Gene3D G3DSA:3.40.50.620 107 441 2.3E-59 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 PRINTS PR01038 Arginyl-tRNA synthetase signature 153 166 3.6E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 PRINTS PR01038 Arginyl-tRNA synthetase signature 305 326 3.6E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 PRINTS PR01038 Arginyl-tRNA synthetase signature 129 145 3.6E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 PRINTS PR01038 Arginyl-tRNA synthetase signature 114 129 3.6E-25 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 Pfam PF05746 DALR anticodon binding domain 462 578 1.9E-36 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 Gene3D G3DSA:3.30.1360.70 1 106 2.7E-26 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 SUPERFAMILY SSF52374 110 455 1.32E-94 T 28-03-2018 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 SMART SM00836 462 578 5.7E-40 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A6A12_RS09950 5710bd15047eab074c942b4130c6bda6 578 SUPERFAMILY SSF47323 456 578 2.81E-35 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS09670 2cf3305ab52a1963e225dfd5694ec373 265 TIGRFAM TIGR03461 pabC_Proteo: aminodeoxychorismate lyase 3 261 4.8E-103 T 28-03-2018 IPR017824 Aminodeoxychorismate lyase, class IV GO:0008696|GO:0030170|GO:0046656 KEGG: 00790+4.1.3.38|MetaCyc: PWY-6543 A6A12_RS09670 2cf3305ab52a1963e225dfd5694ec373 265 SUPERFAMILY SSF56752 1 260 2.09E-68 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A6A12_RS09670 2cf3305ab52a1963e225dfd5694ec373 265 ProSitePatterns PS00770 Aminotransferases class-IV signature. 173 202 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 A6A12_RS09670 2cf3305ab52a1963e225dfd5694ec373 265 Gene3D G3DSA:3.30.470.10 1 110 1.2E-23 T 28-03-2018 A6A12_RS09670 2cf3305ab52a1963e225dfd5694ec373 265 Pfam PF01063 Amino-transferase class IV 24 245 1.3E-42 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A6A12_RS09670 2cf3305ab52a1963e225dfd5694ec373 265 Gene3D G3DSA:3.20.10.10 121 263 2.1E-35 T 28-03-2018 A6A12_RS13780 890ce234ca7432ab4efcaf0be766ed76 724 SUPERFAMILY SSF52540 8 643 1.42E-178 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13780 890ce234ca7432ab4efcaf0be766ed76 724 Gene3D G3DSA:3.40.50.300 386 672 1.7E-52 T 28-03-2018 A6A12_RS13780 890ce234ca7432ab4efcaf0be766ed76 724 Gene3D G3DSA:3.40.50.300 6 144 1.9E-26 T 28-03-2018 A6A12_RS13780 890ce234ca7432ab4efcaf0be766ed76 724 Gene3D G3DSA:3.40.50.300 151 283 2.1E-31 T 28-03-2018 A6A12_RS13780 890ce234ca7432ab4efcaf0be766ed76 724 Gene3D G3DSA:3.40.50.300 284 385 5.3E-26 T 28-03-2018 A6A12_RS13780 890ce234ca7432ab4efcaf0be766ed76 724 TIGRFAM TIGR01075 uvrD: DNA helicase II 7 722 0.0 T 28-03-2018 IPR005753 DNA helicase, ATP-dependent, UvrD type GO:0004003|GO:0005737|GO:0006268 A6A12_RS13780 890ce234ca7432ab4efcaf0be766ed76 724 Pfam PF13361 UvrD-like helicase C-terminal domain 278 616 5.4E-78 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A6A12_RS13780 890ce234ca7432ab4efcaf0be766ed76 724 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 272 1.3E-75 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A6A12_RS10010 a21e8fdaae2ea4063ae02333ed43b5a1 936 Pfam PF00676 Dehydrogenase E1 component 221 517 7.0E-49 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 A6A12_RS10010 a21e8fdaae2ea4063ae02333ed43b5a1 936 Gene3D G3DSA:3.40.50.970 590 799 7.8E-57 T 28-03-2018 A6A12_RS10010 a21e8fdaae2ea4063ae02333ed43b5a1 936 SMART SM00861 594 787 8.5E-64 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A6A12_RS10010 a21e8fdaae2ea4063ae02333ed43b5a1 936 Pfam PF02779 Transketolase, pyrimidine binding domain 594 788 3.8E-66 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A6A12_RS10010 a21e8fdaae2ea4063ae02333ed43b5a1 936 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 12 51 5.9E-14 T 28-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A6A12_RS10010 a21e8fdaae2ea4063ae02333ed43b5a1 936 Gene3D G3DSA:3.40.50.970 168 523 3.0E-90 T 28-03-2018 A6A12_RS10010 a21e8fdaae2ea4063ae02333ed43b5a1 936 SUPERFAMILY SSF52518 123 530 1.99E-88 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS10010 a21e8fdaae2ea4063ae02333ed43b5a1 936 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 792 933 1.0E-51 T 28-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A6A12_RS10010 a21e8fdaae2ea4063ae02333ed43b5a1 936 SUPERFAMILY SSF52518 577 794 4.12E-52 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS10010 a21e8fdaae2ea4063ae02333ed43b5a1 936 Gene3D G3DSA:1.10.287.1150 84 167 2.9E-24 T 28-03-2018 A6A12_RS10010 a21e8fdaae2ea4063ae02333ed43b5a1 936 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 15 933 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A6A12_RS10010 a21e8fdaae2ea4063ae02333ed43b5a1 936 PIRSF PIRSF000157 1 935 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 A6A12_RS03455 869254d855d841523a1b098c09f14111 148 SMART SM00116 84 131 7.4E-9 T 28-03-2018 IPR000644 CBS domain A6A12_RS03455 869254d855d841523a1b098c09f14111 148 SMART SM00116 11 59 6.2E-8 T 28-03-2018 IPR000644 CBS domain A6A12_RS03455 869254d855d841523a1b098c09f14111 148 SUPERFAMILY SSF54631 1 131 6.7E-34 T 28-03-2018 A6A12_RS03455 869254d855d841523a1b098c09f14111 148 Gene3D G3DSA:3.10.580.10 1 148 8.9E-32 T 28-03-2018 A6A12_RS03455 869254d855d841523a1b098c09f14111 148 Pfam PF00571 CBS domain 4 58 3.6E-12 T 28-03-2018 IPR000644 CBS domain A6A12_RS03455 869254d855d841523a1b098c09f14111 148 Pfam PF00571 CBS domain 79 128 4.3E-11 T 28-03-2018 IPR000644 CBS domain A6A12_RS12430 de99eb59cb03140bf9a59f6d17c050ba 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12430 de99eb59cb03140bf9a59f6d17c050ba 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 36.215 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A6A12_RS12430 de99eb59cb03140bf9a59f6d17c050ba 177 Pfam PF00347 Ribosomal protein L6 91 164 9.8E-19 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12430 de99eb59cb03140bf9a59f6d17c050ba 177 Pfam PF00347 Ribosomal protein L6 11 82 5.4E-20 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12430 de99eb59cb03140bf9a59f6d17c050ba 177 Gene3D G3DSA:3.90.930.12 86 177 1.2E-38 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12430 de99eb59cb03140bf9a59f6d17c050ba 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 4.2E-73 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A6A12_RS12430 de99eb59cb03140bf9a59f6d17c050ba 177 Gene3D G3DSA:3.90.930.12 5 85 3.2E-25 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12430 de99eb59cb03140bf9a59f6d17c050ba 177 PIRSF PIRSF002162 1 177 7.6E-43 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12430 de99eb59cb03140bf9a59f6d17c050ba 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 6.1E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A6A12_RS12430 de99eb59cb03140bf9a59f6d17c050ba 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 6.1E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A6A12_RS12430 de99eb59cb03140bf9a59f6d17c050ba 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 6.1E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 A6A12_RS12430 de99eb59cb03140bf9a59f6d17c050ba 177 SUPERFAMILY SSF56053 83 177 2.5E-35 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12430 de99eb59cb03140bf9a59f6d17c050ba 177 SUPERFAMILY SSF56053 1 82 2.75E-24 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS02475 6678d3b8c4a68162c38627a39be85c9b 65 SUPERFAMILY SSF117130 1 54 6.93E-21 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A6A12_RS02475 6678d3b8c4a68162c38627a39be85c9b 65 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 58 3.9E-30 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A6A12_RS02475 6678d3b8c4a68162c38627a39be85c9b 65 Pfam PF02599 Global regulator protein family 1 52 2.0E-26 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A6A12_RS02475 6678d3b8c4a68162c38627a39be85c9b 65 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 4.0E-20 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A6A12_RS02475 6678d3b8c4a68162c38627a39be85c9b 65 Hamap MF_00167 Carbon storage regulator [csrA]. 1 63 20.442 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 A6A12_RS01330 b1e7b8d67995e70c8bd5a2fe0997fc01 326 Gene3D G3DSA:2.80.10.50 116 189 1.6E-14 T 28-03-2018 A6A12_RS01330 b1e7b8d67995e70c8bd5a2fe0997fc01 326 SUPERFAMILY SSF50998 24 324 2.2E-44 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A6A12_RS01330 b1e7b8d67995e70c8bd5a2fe0997fc01 326 Gene3D G3DSA:2.90.10.10 22 115 4.2E-9 T 28-03-2018 IPR001480 Bulb-type lectin domain A6A12_RS01330 b1e7b8d67995e70c8bd5a2fe0997fc01 326 SMART SM00320 285 323 6.5 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 A6A12_RS01330 b1e7b8d67995e70c8bd5a2fe0997fc01 326 SMART SM00320 65 106 110.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 A6A12_RS01330 b1e7b8d67995e70c8bd5a2fe0997fc01 326 SMART SM00320 151 189 1.0E-4 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 A6A12_RS01330 b1e7b8d67995e70c8bd5a2fe0997fc01 326 SMART SM00320 192 230 0.44 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 A6A12_RS01330 b1e7b8d67995e70c8bd5a2fe0997fc01 326 SMART SM00320 236 274 1.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 A6A12_RS01330 b1e7b8d67995e70c8bd5a2fe0997fc01 326 Gene3D G3DSA:2.130.10.10 238 326 8.9E-11 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A6A12_RS01330 b1e7b8d67995e70c8bd5a2fe0997fc01 326 Gene3D G3DSA:1.10.10.670 190 237 1.6E-10 T 28-03-2018 A6A12_RS01330 b1e7b8d67995e70c8bd5a2fe0997fc01 326 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 176 190 - T 28-03-2018 IPR019775 WD40 repeat, conserved site A6A12_RS01330 b1e7b8d67995e70c8bd5a2fe0997fc01 326 Pfam PF00400 WD domain, G-beta repeat 157 189 0.0026 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 A6A12_RS09480 5721adfe611cd440bf7ca81bb4fe8357 100 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 4 83 1.2E-23 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A6A12_RS09480 5721adfe611cd440bf7ca81bb4fe8357 100 SUPERFAMILY SSF46767 2 84 9.94E-25 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A6A12_RS09480 5721adfe611cd440bf7ca81bb4fe8357 100 Gene3D G3DSA:1.10.10.10 1 100 4.2E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS01310 b17274400d2233c17898ab9ae462a770 397 Pfam PF01145 SPFH domain / Band 7 family 90 261 5.4E-29 T 28-03-2018 IPR001107 Band 7 domain A6A12_RS01310 b17274400d2233c17898ab9ae462a770 397 PRINTS PR00721 Stomatin signature 93 115 5.7E-7 T 28-03-2018 IPR001972 Stomatin family GO:0016020 A6A12_RS01310 b17274400d2233c17898ab9ae462a770 397 PRINTS PR00721 Stomatin signature 196 219 5.7E-7 T 28-03-2018 IPR001972 Stomatin family GO:0016020 A6A12_RS01310 b17274400d2233c17898ab9ae462a770 397 PRINTS PR00721 Stomatin signature 140 161 5.7E-7 T 28-03-2018 IPR001972 Stomatin family GO:0016020 A6A12_RS01310 b17274400d2233c17898ab9ae462a770 397 Pfam PF12221 Bacterial membrane protein N terminal 1 57 7.7E-15 T 28-03-2018 IPR020980 Menbrane protein HflK, N-terminal A6A12_RS01310 b17274400d2233c17898ab9ae462a770 397 TIGRFAM TIGR01933 hflK: HflK protein 88 348 1.7E-123 T 28-03-2018 IPR010201 HflK GO:0016021 A6A12_RS01310 b17274400d2233c17898ab9ae462a770 397 SMART SM00244 86 246 7.7E-50 T 28-03-2018 IPR001107 Band 7 domain A6A12_RS01310 b17274400d2233c17898ab9ae462a770 397 SUPERFAMILY SSF117892 120 251 8.37E-22 T 28-03-2018 IPR001107 Band 7 domain A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 PIRSF PIRSF001535 1 571 1.2E-267 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 Pfam PF04073 Aminoacyl-tRNA editing domain 257 378 4.8E-26 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 459 8.5E-42 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 2.4E-16 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 2.4E-16 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 2.4E-16 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 2.4E-16 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 SUPERFAMILY SSF55681 407 478 1.17E-97 T 28-03-2018 A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 SUPERFAMILY SSF55681 10 237 1.17E-97 T 28-03-2018 A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 Gene3D G3DSA:3.30.930.10 1 479 3.3E-100 T 28-03-2018 A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 Gene3D G3DSA:3.40.50.800 480 567 7.0E-28 T 28-03-2018 IPR004154 Anticodon-binding A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 569 8.0E-247 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 Pfam PF03129 Anticodon binding domain 475 568 3.3E-23 T 28-03-2018 IPR004154 Anticodon-binding A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 571 41.204 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 SUPERFAMILY SSF52954 463 570 5.56E-33 T 28-03-2018 IPR004154 Anticodon-binding A6A12_RS03995 77a5c7068f5c4f8ba75dd8831f90f633 571 SUPERFAMILY SSF55826 218 390 2.62E-31 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A6A12_RS13770 518ccd3ed1f7a93a1c6095594bdbc5b9 271 SUPERFAMILY SSF51215 27 146 4.84E-16 T 28-03-2018 A6A12_RS13770 518ccd3ed1f7a93a1c6095594bdbc5b9 271 SUPERFAMILY SSF46689 170 219 2.08E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS13770 518ccd3ed1f7a93a1c6095594bdbc5b9 271 Pfam PF12833 Helix-turn-helix domain 191 267 8.7E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A6A12_RS13770 518ccd3ed1f7a93a1c6095594bdbc5b9 271 Gene3D G3DSA:1.10.10.60 169 229 8.9E-15 T 28-03-2018 A6A12_RS13770 518ccd3ed1f7a93a1c6095594bdbc5b9 271 Gene3D G3DSA:1.10.10.60 230 270 1.5E-11 T 28-03-2018 A6A12_RS13770 518ccd3ed1f7a93a1c6095594bdbc5b9 271 Gene3D G3DSA:2.60.120.10 7 98 6.5E-5 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS13770 518ccd3ed1f7a93a1c6095594bdbc5b9 271 SUPERFAMILY SSF46689 221 268 1.15E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS13770 518ccd3ed1f7a93a1c6095594bdbc5b9 271 Pfam PF02311 AraC-like ligand binding domain 16 146 8.4E-23 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 A6A12_RS13770 518ccd3ed1f7a93a1c6095594bdbc5b9 271 SMART SM00342 185 267 1.0E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 A6A12_RS11695 d2dc415980e33503b8aac15dd4c15e40 476 SUPERFAMILY SSF53613 12 305 1.87E-58 T 28-03-2018 IPR029056 Ribokinase-like A6A12_RS11695 d2dc415980e33503b8aac15dd4c15e40 476 SUPERFAMILY SSF52374 340 471 1.3E-23 T 28-03-2018 A6A12_RS11695 d2dc415980e33503b8aac15dd4c15e40 476 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 51 74 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A6A12_RS11695 d2dc415980e33503b8aac15dd4c15e40 476 Pfam PF01467 Cytidylyltransferase-like 345 469 5.9E-15 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A6A12_RS11695 d2dc415980e33503b8aac15dd4c15e40 476 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 7 312 8.0E-127 T 28-03-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 A6A12_RS11695 d2dc415980e33503b8aac15dd4c15e40 476 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 332 472 8.9E-62 T 28-03-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 A6A12_RS11695 d2dc415980e33503b8aac15dd4c15e40 476 Gene3D G3DSA:3.40.1190.20 7 310 2.3E-55 T 28-03-2018 IPR029056 Ribokinase-like A6A12_RS11695 d2dc415980e33503b8aac15dd4c15e40 476 Gene3D G3DSA:3.40.50.620 324 476 4.7E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS11695 d2dc415980e33503b8aac15dd4c15e40 476 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 342 408 2.4E-18 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A6A12_RS11695 d2dc415980e33503b8aac15dd4c15e40 476 Pfam PF00294 pfkB family carbohydrate kinase 13 302 5.4E-47 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB A6A12_RS11695 d2dc415980e33503b8aac15dd4c15e40 476 Hamap MF_01603 Bifunctional protein HldE [hldE]. 4 474 42.881 T 28-03-2018 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 A6A12_RS06065 5b0ec66d1726218b0682185ed2827260 446 SMART SM00387 340 446 1.9E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS06065 5b0ec66d1726218b0682185ed2827260 446 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 441 4.4E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS06065 5b0ec66d1726218b0682185ed2827260 446 SUPERFAMILY SSF55874 306 443 2.36E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS06065 5b0ec66d1726218b0682185ed2827260 446 Gene3D G3DSA:3.30.565.10 302 445 2.2E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS06065 5b0ec66d1726218b0682185ed2827260 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 390 5.2E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS06065 5b0ec66d1726218b0682185ed2827260 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 425 5.2E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS02295 781eda20595d1aef72bd4a80f48e5aa2 548 Gene3D G3DSA:3.40.50.300 223 547 4.4E-35 T 28-03-2018 A6A12_RS02295 781eda20595d1aef72bd4a80f48e5aa2 548 Gene3D G3DSA:3.40.50.300 16 222 2.3E-34 T 28-03-2018 A6A12_RS02295 781eda20595d1aef72bd4a80f48e5aa2 548 Pfam PF13245 AAA domain 25 201 2.3E-20 T 28-03-2018 A6A12_RS02295 781eda20595d1aef72bd4a80f48e5aa2 548 SUPERFAMILY SSF52540 21 524 3.46E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS02295 781eda20595d1aef72bd4a80f48e5aa2 548 Pfam PF13361 UvrD-like helicase C-terminal domain 225 370 1.2E-8 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A6A12_RS02295 781eda20595d1aef72bd4a80f48e5aa2 548 Pfam PF13361 UvrD-like helicase C-terminal domain 418 518 1.1E-13 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A6A12_RS05630 03393721e6bac2bcd572fc0e68feb33e 533 Pfam PF03553 Na+/H+ antiporter family 165 497 7.9E-104 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A6A12_RS03680 eae647a016d6795c69b3b890990074cd 122 TIGRFAM TIGR03577 EF_0830: conserved hypothetical protein EF_0830/AHA_3911 4 118 3.8E-64 T 28-03-2018 IPR020034 Conserved hypothetical protein CHP03577, EF0830/AHA3911 A6A12_RS03680 eae647a016d6795c69b3b890990074cd 122 Gene3D G3DSA:3.40.1400.10 18 121 8.5E-4 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 A6A12_RS03680 eae647a016d6795c69b3b890990074cd 122 Pfam PF14272 Glycine-rich SFCGS 4 116 9.2E-59 T 28-03-2018 IPR020034 Conserved hypothetical protein CHP03577, EF0830/AHA3911 A6A12_RS12180 68ffcf24058f83b31b035c0bc468356a 92 PRINTS PR00107 Phosphocarrier protein signature 41 56 4.8E-12 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS12180 68ffcf24058f83b31b035c0bc468356a 92 PRINTS PR00107 Phosphocarrier protein signature 56 73 4.8E-12 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS12180 68ffcf24058f83b31b035c0bc468356a 92 PRINTS PR00107 Phosphocarrier protein signature 15 31 4.8E-12 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS12180 68ffcf24058f83b31b035c0bc468356a 92 SUPERFAMILY SSF55594 5 91 1.96E-23 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS12180 68ffcf24058f83b31b035c0bc468356a 92 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 42 57 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site A6A12_RS12180 68ffcf24058f83b31b035c0bc468356a 92 Pfam PF00381 PTS HPr component phosphorylation site 5 85 2.8E-22 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS12180 68ffcf24058f83b31b035c0bc468356a 92 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 15 22 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site A6A12_RS12180 68ffcf24058f83b31b035c0bc468356a 92 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 4 85 3.5E-22 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS12180 68ffcf24058f83b31b035c0bc468356a 92 Gene3D G3DSA:3.30.1340.10 3 90 1.9E-23 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS06245 32552bad545250633fd071bf180a543e 543 Gene3D G3DSA:3.30.450.20 214 322 6.7E-4 T 28-03-2018 A6A12_RS06245 32552bad545250633fd071bf180a543e 543 Gene3D G3DSA:3.30.565.10 379 543 1.8E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS06245 32552bad545250633fd071bf180a543e 543 Gene3D G3DSA:3.30.450.20 43 174 3.3E-21 T 28-03-2018 A6A12_RS06245 32552bad545250633fd071bf180a543e 543 SUPERFAMILY SSF103190 47 175 2.67E-34 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A6A12_RS06245 32552bad545250633fd071bf180a543e 543 SUPERFAMILY SSF55874 425 539 1.83E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS06245 32552bad545250633fd071bf180a543e 543 Pfam PF17203 Single cache domain 3 61 175 1.0E-18 T 28-03-2018 IPR033463 Single cache domain 3 A6A12_RS06245 32552bad545250633fd071bf180a543e 543 SMART SM00387 430 542 2.7E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS06245 32552bad545250633fd071bf180a543e 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 499 6.0E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS06245 32552bad545250633fd071bf180a543e 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 485 6.0E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS06245 32552bad545250633fd071bf180a543e 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 520 6.0E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS06245 32552bad545250633fd071bf180a543e 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 539 6.0E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS06245 32552bad545250633fd071bf180a543e 543 SUPERFAMILY SSF55785 224 321 9.42E-5 T 28-03-2018 IPR000014 PAS domain A6A12_RS06245 32552bad545250633fd071bf180a543e 543 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 433 540 7.5E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS06245 32552bad545250633fd071bf180a543e 543 Gene3D G3DSA:1.10.287.130 323 378 7.0E-14 T 28-03-2018 A6A12_RS06245 32552bad545250633fd071bf180a543e 543 SUPERFAMILY SSF55890 333 407 1.7E-7 T 28-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 A6A12_RS11245 55aee0dcfd052d5c12bb7aa69694df80 337 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 336 2.2E-139 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 A6A12_RS11245 55aee0dcfd052d5c12bb7aa69694df80 337 Gene3D G3DSA:3.40.50.720 2 208 7.1E-38 T 28-03-2018 A6A12_RS11245 55aee0dcfd052d5c12bb7aa69694df80 337 SUPERFAMILY SSF51735 2 336 4.21E-96 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS11245 55aee0dcfd052d5c12bb7aa69694df80 337 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 325 7.7E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS11245 55aee0dcfd052d5c12bb7aa69694df80 337 Gene3D G3DSA:3.90.25.10 209 254 1.6E-11 T 28-03-2018 A6A12_RS11245 55aee0dcfd052d5c12bb7aa69694df80 337 Gene3D G3DSA:3.90.25.10 255 337 4.6E-23 T 28-03-2018 A6A12_RS07800 16b515185e2f8ec70df32d80606ad1ec 327 Pfam PF06996 Type VI secretion, TssG 30 310 1.8E-43 T 28-03-2018 IPR010732 Type VI secretion, TssG-like A6A12_RS02790 38291ba03a4126ba58517e503592bf9f 541 Gene3D G3DSA:1.10.3720.10 39 264 2.0E-32 T 28-03-2018 A6A12_RS02790 38291ba03a4126ba58517e503592bf9f 541 SUPERFAMILY SSF161098 282 535 9.38E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS02790 38291ba03a4126ba58517e503592bf9f 541 SUPERFAMILY SSF161098 7 258 3.27E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS02790 38291ba03a4126ba58517e503592bf9f 541 Gene3D G3DSA:1.10.3720.10 316 540 2.9E-26 T 28-03-2018 A6A12_RS02790 38291ba03a4126ba58517e503592bf9f 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 360 533 5.1E-6 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS02790 38291ba03a4126ba58517e503592bf9f 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 253 1.9E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS06090 1d29cf60c50af74b051b10fe158a8a0c 402 Gene3D G3DSA:1.20.1250.20 207 402 1.0E-14 T 28-03-2018 A6A12_RS06090 1d29cf60c50af74b051b10fe158a8a0c 402 SUPERFAMILY SSF103473 9 400 1.31E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain A6A12_RS06090 1d29cf60c50af74b051b10fe158a8a0c 402 Gene3D G3DSA:1.20.1250.20 5 205 1.9E-32 T 28-03-2018 A6A12_RS06090 1d29cf60c50af74b051b10fe158a8a0c 402 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 15 397 9.3E-117 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 A6A12_RS06090 1d29cf60c50af74b051b10fe158a8a0c 402 Pfam PF07690 Major Facilitator Superfamily 26 364 9.6E-51 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A6A12_RS00400 7cf974f535089c2976e07161ccdf55d2 234 Gene3D G3DSA:3.30.450.40 43 219 0.013 T 28-03-2018 IPR029016 GAF domain-like A6A12_RS00400 7cf974f535089c2976e07161ccdf55d2 234 Pfam PF04340 Protein of unknown function, DUF484 6 222 2.2E-72 T 28-03-2018 IPR007435 Protein of unknown function DUF484 A6A12_RS09905 d6f7ad4a88a0378fe902af40a499d39d 238 PIRSF PIRSF002884 13 238 1.2E-93 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 A6A12_RS09905 d6f7ad4a88a0378fe902af40a499d39d 238 Gene3D G3DSA:1.10.287.500 56 189 5.0E-19 T 28-03-2018 A6A12_RS09905 d6f7ad4a88a0378fe902af40a499d39d 238 Gene3D G3DSA:1.20.5.590 31 53 8.2E-4 T 28-03-2018 A6A12_RS09905 d6f7ad4a88a0378fe902af40a499d39d 238 SUPERFAMILY SSF75708 26 237 3.01E-67 T 28-03-2018 A6A12_RS09905 d6f7ad4a88a0378fe902af40a499d39d 238 Pfam PF04344 Chemotaxis phosphatase, CheZ 37 238 3.3E-78 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 A6A12_RS08125 67bd719339496c057cc612a61a0bf3a5 257 Gene3D G3DSA:3.30.460.10 65 190 1.1E-9 T 28-03-2018 A6A12_RS08125 67bd719339496c057cc612a61a0bf3a5 257 SUPERFAMILY SSF81301 63 214 3.43E-14 T 28-03-2018 A6A12_RS13190 1f1e7c75e9f24c86879b9c94b8458d6d 388 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 301 371 2.7E-7 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A6A12_RS13190 1f1e7c75e9f24c86879b9c94b8458d6d 388 Gene3D G3DSA:3.40.50.720 288 388 3.0E-17 T 28-03-2018 A6A12_RS13190 1f1e7c75e9f24c86879b9c94b8458d6d 388 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 192 281 7.6E-27 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A6A12_RS13190 1f1e7c75e9f24c86879b9c94b8458d6d 388 Gene3D G3DSA:3.40.50.720 1 193 2.1E-51 T 28-03-2018 A6A12_RS13190 1f1e7c75e9f24c86879b9c94b8458d6d 388 PIRSF PIRSF500134 338 388 0.046 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 A6A12_RS13190 1f1e7c75e9f24c86879b9c94b8458d6d 388 PIRSF PIRSF500134 1 343 2.0E-123 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 A6A12_RS13190 1f1e7c75e9f24c86879b9c94b8458d6d 388 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 377 2.1E-105 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A6A12_RS13190 1f1e7c75e9f24c86879b9c94b8458d6d 388 Gene3D G3DSA:1.20.5.100 194 211 2.8E-14 T 28-03-2018 A6A12_RS13190 1f1e7c75e9f24c86879b9c94b8458d6d 388 SUPERFAMILY SSF52413 283 387 9.02E-28 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A6A12_RS13190 1f1e7c75e9f24c86879b9c94b8458d6d 388 SMART SM00984 300 387 1.6E-13 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A6A12_RS13190 1f1e7c75e9f24c86879b9c94b8458d6d 388 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 168 1.4E-33 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A6A12_RS13190 1f1e7c75e9f24c86879b9c94b8458d6d 388 Gene3D G3DSA:1.10.1040.10 212 287 1.1E-27 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A6A12_RS13190 1f1e7c75e9f24c86879b9c94b8458d6d 388 SUPERFAMILY SSF51735 1 194 4.71E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS13190 1f1e7c75e9f24c86879b9c94b8458d6d 388 PIRSF PIRSF000124 1 388 4.5E-138 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A6A12_RS13190 1f1e7c75e9f24c86879b9c94b8458d6d 388 SUPERFAMILY SSF48179 191 287 1.02E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A6A12_RS09190 598934a2965537fd1baec8b64055bec2 714 SUPERFAMILY SSF52540 1 240 1.95E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09190 598934a2965537fd1baec8b64055bec2 714 SUPERFAMILY SSF75138 229 353 2.35E-24 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A6A12_RS09190 598934a2965537fd1baec8b64055bec2 714 Gene3D G3DSA:3.40.1390.20 230 366 3.2E-29 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like A6A12_RS09190 598934a2965537fd1baec8b64055bec2 714 PIRSF PIRSF006107 1 714 0.0 T 28-03-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A6A12_RS09190 598934a2965537fd1baec8b64055bec2 714 SUPERFAMILY SSF53659 392 709 2.34E-95 T 28-03-2018 A6A12_RS09190 598934a2965537fd1baec8b64055bec2 714 Pfam PF13500 AAA domain 3 229 9.8E-51 T 28-03-2018 A6A12_RS09190 598934a2965537fd1baec8b64055bec2 714 Pfam PF07085 DRTGG domain 233 344 6.3E-28 T 28-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A6A12_RS09190 598934a2965537fd1baec8b64055bec2 714 Pfam PF01515 Phosphate acetyl/butaryl transferase 391 706 1.1E-124 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A6A12_RS09190 598934a2965537fd1baec8b64055bec2 714 Gene3D G3DSA:3.40.50.300 1 229 3.8E-24 T 28-03-2018 A6A12_RS09190 598934a2965537fd1baec8b64055bec2 714 Gene3D G3DSA:3.40.50.10750 529 682 1.0E-64 T 28-03-2018 A6A12_RS09190 598934a2965537fd1baec8b64055bec2 714 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 406 706 3.7E-132 T 28-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 Gene3D G3DSA:3.50.50.60 3 162 1.8E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 PIRSF PIRSF000350 1 463 1.1E-70 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 263 277 2.5E-52 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 2.5E-52 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 2.5E-52 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 313 2.5E-52 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 2.5E-52 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 2.5E-52 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 151 2.5E-52 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 2.5E-52 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 2.5E-52 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 Hamap MF_00247 Soluble pyridine nucleotide transhydrogenase [sthA]. 2 466 64.346 T 28-03-2018 IPR022962 Soluble pyridine nucleotide transhydrogenase GO:0003957|GO:0055114 KEGG: 00760+1.6.1.1|MetaCyc: PWY-5083 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 Gene3D G3DSA:3.30.390.30 335 463 3.0E-34 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 SUPERFAMILY SSF51905 1 319 2.21E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 326 4.3E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 7.5E-29 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 139 157 7.5E-29 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 7.5E-29 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 291 313 7.5E-29 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 278 7.5E-29 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 Gene3D G3DSA:3.40.50.720 163 334 2.7E-28 T 28-03-2018 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 SUPERFAMILY SSF55424 344 463 8.76E-31 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 A6A12_RS00605 e3f16941f54f2247e390ccd8563cb553 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 457 5.7E-30 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A6A12_RS00990 5e0f0737c098d4c5338b79fa191c7b5a 1092 Gene3D G3DSA:2.60.40.10 256 327 3.2E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS00990 5e0f0737c098d4c5338b79fa191c7b5a 1092 Gene3D G3DSA:1.10.530.10 708 1092 2.5E-60 T 28-03-2018 A6A12_RS00990 5e0f0737c098d4c5338b79fa191c7b5a 1092 SUPERFAMILY SSF51055 342 392 7.85E-13 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A6A12_RS00990 5e0f0737c098d4c5338b79fa191c7b5a 1092 SMART SM00495 347 388 5.1E-5 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A6A12_RS00990 5e0f0737c098d4c5338b79fa191c7b5a 1092 SMART SM00495 76 121 4.6 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A6A12_RS00990 5e0f0737c098d4c5338b79fa191c7b5a 1092 SMART SM00495 14 59 2.2 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A6A12_RS00990 5e0f0737c098d4c5338b79fa191c7b5a 1092 Gene3D G3DSA:2.40.50.70 209 255 1.4E-4 T 28-03-2018 A6A12_RS00990 5e0f0737c098d4c5338b79fa191c7b5a 1092 Gene3D G3DSA:2.60.40.10 130 208 0.14 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS00990 5e0f0737c098d4c5338b79fa191c7b5a 1092 Gene3D G3DSA:2.10.10.20 336 392 6.9E-9 T 28-03-2018 A6A12_RS00990 5e0f0737c098d4c5338b79fa191c7b5a 1092 Pfam PF14600 Cellulose-binding domain 340 392 1.6E-13 T 28-03-2018 IPR032798 Endoglucanase Z, cellulose-binding domain KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 A6A12_RS03800 b8466e021ffb2b22aa66ab92abbdbcd8 147 Pfam PF10980 Protein of unknown function (DUF2787) 16 141 3.4E-40 T 28-03-2018 IPR021248 Protein of unknown function DUF2787 A6A12_RS01290 52d3cceeeee7465db9c661b8c972dedd 660 SUPERFAMILY SSF118116 475 657 3.79E-37 T 28-03-2018 A6A12_RS01290 52d3cceeeee7465db9c661b8c972dedd 660 SMART SM01340 214 332 1.2E-58 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 A6A12_RS01290 52d3cceeeee7465db9c661b8c972dedd 660 Gene3D G3DSA:3.30.565.10 3 218 3.3E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS01290 52d3cceeeee7465db9c661b8c972dedd 660 Pfam PF08676 MutL C terminal dimerisation domain 475 617 3.5E-28 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 A6A12_RS01290 52d3cceeeee7465db9c661b8c972dedd 660 SUPERFAMILY SSF55874 2 205 4.71E-53 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS01290 52d3cceeeee7465db9c661b8c972dedd 660 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 121 1.7E-11 T 28-03-2018 A6A12_RS01290 52d3cceeeee7465db9c661b8c972dedd 660 Gene3D G3DSA:3.30.230.10 219 331 8.5E-32 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A6A12_RS01290 52d3cceeeee7465db9c661b8c972dedd 660 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 214 331 7.2E-40 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 A6A12_RS01290 52d3cceeeee7465db9c661b8c972dedd 660 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 3 658 25.298 T 28-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 A6A12_RS01290 52d3cceeeee7465db9c661b8c972dedd 660 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 312 1.3E-101 T 28-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 A6A12_RS01290 52d3cceeeee7465db9c661b8c972dedd 660 SUPERFAMILY SSF54211 193 332 1.52E-37 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS01290 52d3cceeeee7465db9c661b8c972dedd 660 SMART SM00853 478 619 5.3E-13 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 A6A12_RS01290 52d3cceeeee7465db9c661b8c972dedd 660 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 95 101 - T 28-03-2018 IPR014762 DNA mismatch repair, conserved site A6A12_RS05475 2bf29eb68cbc6faad679ebd2f28ad5ce 573 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 7 533 1.1E-136 T 28-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 A6A12_RS05475 2bf29eb68cbc6faad679ebd2f28ad5ce 573 Gene3D G3DSA:3.40.50.300 324 572 2.9E-69 T 28-03-2018 A6A12_RS05475 2bf29eb68cbc6faad679ebd2f28ad5ce 573 Gene3D G3DSA:1.20.1560.10 2 323 1.3E-27 T 28-03-2018 A6A12_RS05475 2bf29eb68cbc6faad679ebd2f28ad5ce 573 Pfam PF00664 ABC transporter transmembrane region 23 287 2.8E-7 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A6A12_RS05475 2bf29eb68cbc6faad679ebd2f28ad5ce 573 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS05475 2bf29eb68cbc6faad679ebd2f28ad5ce 573 SUPERFAMILY SSF52540 334 571 2.25E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05475 2bf29eb68cbc6faad679ebd2f28ad5ce 573 SMART SM00382 365 549 1.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS05475 2bf29eb68cbc6faad679ebd2f28ad5ce 573 Pfam PF00005 ABC transporter 356 502 2.9E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS05475 2bf29eb68cbc6faad679ebd2f28ad5ce 573 SUPERFAMILY SSF90123 7 323 1.96E-36 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 A6A12_RS11420 92ef3f642041cd14b6020a354e9185a3 1487 Gene3D G3DSA:2.160.20.60 1212 1485 1.9E-92 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A6A12_RS11420 92ef3f642041cd14b6020a354e9185a3 1487 Gene3D G3DSA:3.60.20.10 13 438 9.5E-145 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A6A12_RS11420 92ef3f642041cd14b6020a354e9185a3 1487 Gene3D G3DSA:3.20.20.70 781 1208 3.1E-143 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS11420 92ef3f642041cd14b6020a354e9185a3 1487 Pfam PF00310 Glutamine amidotransferases class-II 13 426 1.5E-176 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain A6A12_RS11420 92ef3f642041cd14b6020a354e9185a3 1487 Pfam PF01493 GXGXG motif 1236 1420 2.2E-72 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A6A12_RS11420 92ef3f642041cd14b6020a354e9185a3 1487 Pfam PF04898 Glutamate synthase central domain 458 738 1.4E-104 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 A6A12_RS11420 92ef3f642041cd14b6020a354e9185a3 1487 SUPERFAMILY SSF51395 434 1191 1.34E-250 T 28-03-2018 A6A12_RS11420 92ef3f642041cd14b6020a354e9185a3 1487 Gene3D G3DSA:3.20.20.70 440 780 2.0E-80 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS11420 92ef3f642041cd14b6020a354e9185a3 1487 SUPERFAMILY SSF69336 1212 1464 1.06E-85 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A6A12_RS11420 92ef3f642041cd14b6020a354e9185a3 1487 SUPERFAMILY SSF56235 13 429 6.18E-147 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A6A12_RS11420 92ef3f642041cd14b6020a354e9185a3 1487 Pfam PF01645 Conserved region in glutamate synthase 794 1157 3.3E-151 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 SMART SM00495 323 372 1.9E-6 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 SMART SM00495 74 120 3.0E-8 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 SUPERFAMILY SSF51055 65 123 1.65E-11 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 Gene3D G3DSA:2.60.40.10 250 309 6.9E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 Gene3D G3DSA:2.60.40.10 155 205 0.0038 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 Gene3D G3DSA:2.60.40.10 501 567 0.0057 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 Gene3D G3DSA:2.40.50.70 456 500 1.5E-9 T 28-03-2018 A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 Gene3D G3DSA:2.40.50.70 377 416 1.9E-13 T 28-03-2018 A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 Gene3D G3DSA:2.40.50.70 206 249 1.9E-15 T 28-03-2018 A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 Gene3D G3DSA:2.40.50.70 123 154 6.3E-15 T 28-03-2018 A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 SMART SM00636 568 870 1.4E-4 T 28-03-2018 IPR011583 Chitinase II GO:0008061 A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 Gene3D G3DSA:3.20.20.80 568 892 5.5E-41 T 28-03-2018 A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 SUPERFAMILY SSF51445 566 878 1.76E-48 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 Gene3D G3DSA:2.60.40.10 417 455 0.022 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 Pfam PF00704 Glycosyl hydrolases family 18 570 870 4.3E-26 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 Gene3D G3DSA:2.10.10.20 60 122 2.3E-10 T 28-03-2018 A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 Gene3D G3DSA:2.10.10.20 310 376 1.3E-7 T 28-03-2018 A6A12_RS05070 24d507b9fce68194a0e62d940051383c 892 ProSitePatterns PS01095 Chitinases family 18 active site. 682 690 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A6A12_RS03155 cf18c5963cfbf7b11853a13a0a3231b9 283 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 282 8.6E-40 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A6A12_RS03155 cf18c5963cfbf7b11853a13a0a3231b9 283 Gene3D G3DSA:3.30.572.10 1 283 1.2E-77 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A6A12_RS03155 cf18c5963cfbf7b11853a13a0a3231b9 283 Hamap MF_00008 Thymidylate synthase [thyA]. 1 283 31.611 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A6A12_RS03155 cf18c5963cfbf7b11853a13a0a3231b9 283 SUPERFAMILY SSF55831 2 283 7.46E-88 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A6A12_RS03155 cf18c5963cfbf7b11853a13a0a3231b9 283 Pfam PF00303 Thymidylate synthase 2 283 7.8E-73 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A6A12_RS03155 cf18c5963cfbf7b11853a13a0a3231b9 283 PRINTS PR00108 Thymidylate synthase family signature 173 199 6.4E-13 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A6A12_RS03155 cf18c5963cfbf7b11853a13a0a3231b9 283 PRINTS PR00108 Thymidylate synthase family signature 44 65 6.4E-13 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A6A12_RS03155 cf18c5963cfbf7b11853a13a0a3231b9 283 PRINTS PR00108 Thymidylate synthase family signature 129 148 6.4E-13 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A6A12_RS03155 cf18c5963cfbf7b11853a13a0a3231b9 283 PRINTS PR00108 Thymidylate synthase family signature 211 228 6.4E-13 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A6A12_RS11675 303f460500b3d6795a799ffc1f073386 273 Gene3D G3DSA:3.60.21.10 2 268 1.7E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A6A12_RS11675 303f460500b3d6795a799ffc1f073386 273 Pfam PF00149 Calcineurin-like phosphoesterase 14 204 1.5E-14 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A6A12_RS11675 303f460500b3d6795a799ffc1f073386 273 SUPERFAMILY SSF56300 13 269 2.63E-56 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A6A12_RS11675 303f460500b3d6795a799ffc1f073386 273 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 204 259 1.0E-20 T 28-03-2018 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 A6A12_RS11675 303f460500b3d6795a799ffc1f073386 273 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 13 259 40.832 T 28-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 A6A12_RS00255 154ac3b7b306118a53808771aa7ef601 426 Gene3D G3DSA:1.10.287.730 143 168 7.6E-12 T 28-03-2018 A6A12_RS00255 154ac3b7b306118a53808771aa7ef601 426 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 313 324 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS00255 154ac3b7b306118a53808771aa7ef601 426 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 4 426 9.9E-148 T 28-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS00255 154ac3b7b306118a53808771aa7ef601 426 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 364 380 1.7E-30 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS00255 154ac3b7b306118a53808771aa7ef601 426 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 314 326 1.7E-30 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS00255 154ac3b7b306118a53808771aa7ef601 426 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 407 424 1.7E-30 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS00255 154ac3b7b306118a53808771aa7ef601 426 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 219 233 1.7E-30 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS00255 154ac3b7b306118a53808771aa7ef601 426 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 248 258 1.7E-30 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS00255 154ac3b7b306118a53808771aa7ef601 426 Gene3D G3DSA:3.30.70.1170 170 227 2.0E-16 T 28-03-2018 A6A12_RS00255 154ac3b7b306118a53808771aa7ef601 426 SUPERFAMILY SSF53335 139 424 1.48E-75 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS00255 154ac3b7b306118a53808771aa7ef601 426 SUPERFAMILY SSF48013 1 146 2.22E-35 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A6A12_RS00255 154ac3b7b306118a53808771aa7ef601 426 Pfam PF01029 NusB family 1 123 1.9E-25 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A6A12_RS00255 154ac3b7b306118a53808771aa7ef601 426 Gene3D G3DSA:1.10.940.10 1 142 1.9E-30 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A6A12_RS00255 154ac3b7b306118a53808771aa7ef601 426 Gene3D G3DSA:3.40.50.150 228 426 2.5E-55 T 28-03-2018 A6A12_RS00255 154ac3b7b306118a53808771aa7ef601 426 Pfam PF01189 16S rRNA methyltransferase RsmB/F 238 422 2.0E-67 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS00870 bbd1bf8103e577b0ad9ef0374a7fb641 406 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 403 8.0E-156 T 28-03-2018 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 A6A12_RS00870 bbd1bf8103e577b0ad9ef0374a7fb641 406 Pfam PF00482 Type II secretion system (T2SS), protein F 274 396 1.2E-24 T 28-03-2018 IPR018076 Type II secretion system F domain A6A12_RS00870 bbd1bf8103e577b0ad9ef0374a7fb641 406 Pfam PF00482 Type II secretion system (T2SS), protein F 72 194 1.3E-34 T 28-03-2018 IPR018076 Type II secretion system F domain A6A12_RS00870 bbd1bf8103e577b0ad9ef0374a7fb641 406 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 166 194 - T 28-03-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 A6A12_RS00870 bbd1bf8103e577b0ad9ef0374a7fb641 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 166 194 1.2E-37 T 28-03-2018 IPR003004 GspF/PilC family A6A12_RS00870 bbd1bf8103e577b0ad9ef0374a7fb641 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 369 383 1.2E-37 T 28-03-2018 IPR003004 GspF/PilC family A6A12_RS00870 bbd1bf8103e577b0ad9ef0374a7fb641 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 385 404 1.2E-37 T 28-03-2018 IPR003004 GspF/PilC family A6A12_RS00870 bbd1bf8103e577b0ad9ef0374a7fb641 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 67 79 1.2E-37 T 28-03-2018 IPR003004 GspF/PilC family A6A12_RS00870 bbd1bf8103e577b0ad9ef0374a7fb641 406 Gene3D G3DSA:1.20.1180.10 60 119 0.0054 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 Gene3D G3DSA:3.30.390.10 3 127 7.2E-51 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 SMART SM01192 143 431 1.0E-210 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 PIRSF PIRSF001400 1 430 4.4E-191 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 Hamap MF_00318 Enolase [eno]. 2 417 44.261 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 SMART SM01193 4 134 7.7E-93 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 Gene3D G3DSA:3.20.20.120 128 432 1.7E-99 T 28-03-2018 IPR029065 Enolase C-terminal domain-like A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 Pfam PF03952 Enolase, N-terminal domain 4 134 5.1E-58 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 Pfam PF00113 Enolase, C-terminal TIM barrel domain 144 430 1.0E-135 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 SUPERFAMILY SSF51604 143 428 1.7E-125 T 28-03-2018 IPR029065 Enolase C-terminal domain-like A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 429 8.1E-206 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 ProSitePatterns PS00164 Enolase signature. 340 353 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 SUPERFAMILY SSF54826 3 138 1.27E-56 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 PRINTS PR00148 Enolase signature 369 386 4.0E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 PRINTS PR00148 Enolase signature 317 328 4.0E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 PRINTS PR00148 Enolase signature 165 178 4.0E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 PRINTS PR00148 Enolase signature 340 354 4.0E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 PRINTS PR00148 Enolase signature 37 51 4.0E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS11750 c242d19f7776ab3f5d2ae2bbf23fa684 433 PRINTS PR00148 Enolase signature 107 123 4.0E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS08240 52285bdacd1df4ab2c6d8c6787f813f7 241 Gene3D G3DSA:3.10.129.10 8 212 0.0013 T 28-03-2018 A6A12_RS08240 52285bdacd1df4ab2c6d8c6787f813f7 241 Pfam PF12119 Protein of unknown function (DUF3581) 1 217 4.4E-97 T 28-03-2018 IPR021974 Protein of unknown function DUF3581 A6A12_RS02405 4686ce65ff88344840547a280050eff7 208 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 5 206 1.2E-83 T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A6A12_RS02405 4686ce65ff88344840547a280050eff7 208 SUPERFAMILY SSF53335 13 204 8.91E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS02405 4686ce65ff88344840547a280050eff7 208 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 7 204 5.6E-72 T 28-03-2018 A6A12_RS02405 4686ce65ff88344840547a280050eff7 208 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 130 145 - T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A6A12_RS02405 4686ce65ff88344840547a280050eff7 208 Gene3D G3DSA:3.40.50.150 11 206 3.9E-33 T 28-03-2018 A6A12_RS02405 4686ce65ff88344840547a280050eff7 208 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 1 208 38.955 T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A6A12_RS01255 ac616b94470135c110a39c842be6129f 181 SUPERFAMILY SSF53098 3 179 3.92E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS01255 ac616b94470135c110a39c842be6129f 181 Pfam PF00929 Exonuclease 9 170 8.7E-36 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS01255 ac616b94470135c110a39c842be6129f 181 SMART SM00479 7 180 4.4E-22 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS01255 ac616b94470135c110a39c842be6129f 181 Gene3D G3DSA:3.30.420.10 2 181 1.3E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS01255 ac616b94470135c110a39c842be6129f 181 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 43.122 T 28-03-2018 IPR022894 Oligoribonuclease GO:0000175 A6A12_RS05675 cba0d7e1510366e0bf840e32b6e82c31 261 Gene3D G3DSA:3.30.2350.10 81 261 2.3E-38 T 28-03-2018 A6A12_RS05675 cba0d7e1510366e0bf840e32b6e82c31 261 Pfam PF00849 RNA pseudouridylate synthase 86 230 1.5E-14 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS05675 cba0d7e1510366e0bf840e32b6e82c31 261 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 121 135 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A6A12_RS05675 cba0d7e1510366e0bf840e32b6e82c31 261 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 90 260 8.4E-58 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A6A12_RS05675 cba0d7e1510366e0bf840e32b6e82c31 261 SUPERFAMILY SSF55120 75 260 1.14E-44 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS05380 797f87e094743156d8971f6faafa6c93 188 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 1 176 3.9E-64 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 A6A12_RS05380 797f87e094743156d8971f6faafa6c93 188 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 175 18.554 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 A6A12_RS05380 797f87e094743156d8971f6faafa6c93 188 Pfam PF04279 Intracellular septation protein A 1 174 3.0E-67 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 A6A12_RS10620 ce04eb11d7c3a29327a1e752bfb77f22 259 PRINTS PR01008 Flagellar L-ring protein signature 222 236 4.9E-22 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 A6A12_RS10620 ce04eb11d7c3a29327a1e752bfb77f22 259 PRINTS PR01008 Flagellar L-ring protein signature 201 217 4.9E-22 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 A6A12_RS10620 ce04eb11d7c3a29327a1e752bfb77f22 259 PRINTS PR01008 Flagellar L-ring protein signature 238 252 4.9E-22 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 A6A12_RS10620 ce04eb11d7c3a29327a1e752bfb77f22 259 PRINTS PR01008 Flagellar L-ring protein signature 103 115 4.9E-22 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 A6A12_RS10620 ce04eb11d7c3a29327a1e752bfb77f22 259 PRINTS PR01008 Flagellar L-ring protein signature 175 190 4.9E-22 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 A6A12_RS10620 ce04eb11d7c3a29327a1e752bfb77f22 259 Pfam PF02107 Flagellar L-ring protein 81 256 4.4E-58 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 A6A12_RS10620 ce04eb11d7c3a29327a1e752bfb77f22 259 Hamap MF_00415 Flagellar L-ring protein [flgH]. 1 259 28.279 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 A6A12_RS09545 95b8ac33178291c7db4e2db5d7668a85 288 Gene3D G3DSA:3.90.226.10 10 227 3.0E-63 T 28-03-2018 A6A12_RS09545 95b8ac33178291c7db4e2db5d7668a85 288 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 126 146 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 A6A12_RS09545 95b8ac33178291c7db4e2db5d7668a85 288 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 18 287 56.227 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 A6A12_RS09545 95b8ac33178291c7db4e2db5d7668a85 288 SUPERFAMILY SSF52096 17 284 3.24E-79 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS09545 95b8ac33178291c7db4e2db5d7668a85 288 Pfam PF00378 Enoyl-CoA hydratase/isomerase 34 282 3.9E-78 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 A6A12_RS09545 95b8ac33178291c7db4e2db5d7668a85 288 Gene3D G3DSA:1.10.12.10 228 276 6.3E-14 T 28-03-2018 IPR014748 Crontonase, C-terminal A6A12_RS09545 95b8ac33178291c7db4e2db5d7668a85 288 TIGRFAM TIGR01929 menB: naphthoate synthase 25 284 2.7E-146 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 A6A12_RS06815 df09617b8e5391ee01403d5bf7294c76 443 Gene3D G3DSA:1.20.1250.20 235 438 8.0E-27 T 28-03-2018 A6A12_RS06815 df09617b8e5391ee01403d5bf7294c76 443 Gene3D G3DSA:1.20.1250.20 18 213 4.7E-30 T 28-03-2018 A6A12_RS06815 df09617b8e5391ee01403d5bf7294c76 443 Pfam PF07690 Major Facilitator Superfamily 36 395 4.4E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A6A12_RS06815 df09617b8e5391ee01403d5bf7294c76 443 PIRSF PIRSF002808 6 442 2.0E-135 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 A6A12_RS06815 df09617b8e5391ee01403d5bf7294c76 443 SUPERFAMILY SSF103473 13 433 7.32E-80 T 28-03-2018 IPR020846 Major facilitator superfamily domain A6A12_RS06815 df09617b8e5391ee01403d5bf7294c76 443 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 35 412 8.8E-135 T 28-03-2018 A6A12_RS08580 6ba0387e40ea0895d8f3b16841740070 187 Pfam PF05869 DNA N-6-adenine-methyltransferase (Dam) 8 182 3.2E-42 T 28-03-2018 IPR008593 DNA N-6-adenine-methyltransferase GO:0003677|GO:0009007|GO:0032775 A6A12_RS08580 6ba0387e40ea0895d8f3b16841740070 187 TIGRFAM TIGR01712 phage_N6A_met: phage N-6-adenine-methyltransferase 10 179 1.2E-39 T 28-03-2018 IPR008593 DNA N-6-adenine-methyltransferase GO:0003677|GO:0009007|GO:0032775 A6A12_RS03560 6a00d02fe2d2c14a41647fe96d6b8c27 422 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 420 33.776 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A6A12_RS03560 6a00d02fe2d2c14a41647fe96d6b8c27 422 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 410 6.5E-159 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A6A12_RS03560 6a00d02fe2d2c14a41647fe96d6b8c27 422 SUPERFAMILY SSF52954 327 420 1.6E-26 T 28-03-2018 IPR004154 Anticodon-binding A6A12_RS03560 6a00d02fe2d2c14a41647fe96d6b8c27 422 Gene3D G3DSA:3.40.50.800 325 422 1.1E-17 T 28-03-2018 IPR004154 Anticodon-binding A6A12_RS03560 6a00d02fe2d2c14a41647fe96d6b8c27 422 PIRSF PIRSF001549 2 422 3.2E-124 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A6A12_RS03560 6a00d02fe2d2c14a41647fe96d6b8c27 422 Pfam PF13393 Histidyl-tRNA synthetase 10 312 4.3E-46 T 28-03-2018 A6A12_RS03560 6a00d02fe2d2c14a41647fe96d6b8c27 422 Gene3D G3DSA:3.30.930.10 2 324 2.3E-73 T 28-03-2018 A6A12_RS03560 6a00d02fe2d2c14a41647fe96d6b8c27 422 Pfam PF03129 Anticodon binding domain 333 419 8.9E-11 T 28-03-2018 IPR004154 Anticodon-binding A6A12_RS03560 6a00d02fe2d2c14a41647fe96d6b8c27 422 SUPERFAMILY SSF55681 5 319 3.19E-104 T 28-03-2018 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 Gene3D G3DSA:3.40.50.1980 26 222 1.7E-86 T 28-03-2018 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 PIRSF PIRSF000099 1 427 5.4E-169 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 4 424 41.925 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 SUPERFAMILY SSF53720 4 424 3.14E-92 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 Pfam PF00815 Histidinol dehydrogenase 26 424 1.3E-169 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 PRINTS PR00083 Histidinol dehydrogenase signature 249 268 1.6E-100 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 PRINTS PR00083 Histidinol dehydrogenase signature 358 376 1.6E-100 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 1.6E-100 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 PRINTS PR00083 Histidinol dehydrogenase signature 134 160 1.6E-100 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 PRINTS PR00083 Histidinol dehydrogenase signature 165 191 1.6E-100 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 PRINTS PR00083 Histidinol dehydrogenase signature 227 248 1.6E-100 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 PRINTS PR00083 Histidinol dehydrogenase signature 317 342 1.6E-100 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 PRINTS PR00083 Histidinol dehydrogenase signature 195 220 1.6E-100 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 Gene3D G3DSA:3.40.50.1980 223 368 4.3E-69 T 28-03-2018 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 227 259 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 A6A12_RS05640 5ebae3e3c6ba17f5ae6377ed815ff913 432 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 423 1.1E-164 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 A6A12_RS04295 4d7d03ad0644226d39f5c33362684574 233 Gene3D G3DSA:1.25.40.10 19 140 0.0014 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS06780 8f9f4b4faef6e5cb8e7c734c80a497e3 344 Pfam PF13416 Bacterial extracellular solute-binding protein 43 310 7.4E-38 T 28-03-2018 A6A12_RS06780 8f9f4b4faef6e5cb8e7c734c80a497e3 344 Gene3D G3DSA:3.40.190.10 21 191 1.7E-30 T 28-03-2018 A6A12_RS06780 8f9f4b4faef6e5cb8e7c734c80a497e3 344 Gene3D G3DSA:3.40.190.10 192 312 3.1E-17 T 28-03-2018 A6A12_RS06780 8f9f4b4faef6e5cb8e7c734c80a497e3 344 SUPERFAMILY SSF53850 28 331 7.41E-86 T 28-03-2018 A6A12_RS06780 8f9f4b4faef6e5cb8e7c734c80a497e3 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 167 186 6.7E-71 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06780 8f9f4b4faef6e5cb8e7c734c80a497e3 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 49 70 6.7E-71 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06780 8f9f4b4faef6e5cb8e7c734c80a497e3 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 204 223 6.7E-71 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06780 8f9f4b4faef6e5cb8e7c734c80a497e3 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 248 267 6.7E-71 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06780 8f9f4b4faef6e5cb8e7c734c80a497e3 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 33 49 6.7E-71 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06780 8f9f4b4faef6e5cb8e7c734c80a497e3 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 76 90 6.7E-71 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06780 8f9f4b4faef6e5cb8e7c734c80a497e3 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 92 105 6.7E-71 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06780 8f9f4b4faef6e5cb8e7c734c80a497e3 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 123 139 6.7E-71 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06780 8f9f4b4faef6e5cb8e7c734c80a497e3 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 149 163 6.7E-71 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06780 8f9f4b4faef6e5cb8e7c734c80a497e3 344 PIRSF PIRSF019574 1 344 2.6E-110 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 A6A12_RS06655 5fe09546935cb05c0aa84cf041a70a44 172 SUPERFAMILY SSF54637 4 169 4.97E-57 T 28-03-2018 IPR029069 HotDog domain A6A12_RS06655 5fe09546935cb05c0aa84cf041a70a44 172 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 4 172 3.3E-92 T 28-03-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A6A12_RS06655 5fe09546935cb05c0aa84cf041a70a44 172 Gene3D G3DSA:3.10.129.10 1 172 1.9E-49 T 28-03-2018 A6A12_RS06655 5fe09546935cb05c0aa84cf041a70a44 172 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 2 172 51.612 T 28-03-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A6A12_RS06655 5fe09546935cb05c0aa84cf041a70a44 172 Pfam PF07977 FabA-like domain 29 158 3.4E-54 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A6A12_RS10775 cb01fb5a2b4f1bf81cefacbd380f42d9 423 TIGRFAM TIGR03503 TIGR03503: TIGR03503 family protein 31 407 7.6E-137 T 28-03-2018 IPR020010 Conserved hypothetical protein CHP03503 A6A12_RS01880 cc180c53aaa0eabf205185f00d18c223 351 SMART SM00478 37 188 8.8E-50 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A6A12_RS01880 cc180c53aaa0eabf205185f00d18c223 351 SMART SM00525 189 209 1.9E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A6A12_RS01880 cc180c53aaa0eabf205185f00d18c223 351 SUPERFAMILY SSF55811 218 345 4.61E-27 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A6A12_RS01880 cc180c53aaa0eabf205185f00d18c223 351 SUPERFAMILY SSF48150 3 223 9.58E-76 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A6A12_RS01880 cc180c53aaa0eabf205185f00d18c223 351 Gene3D G3DSA:1.10.340.30 19 117 3.0E-32 T 28-03-2018 A6A12_RS01880 cc180c53aaa0eabf205185f00d18c223 351 Pfam PF14815 NUDIX domain 231 343 5.7E-24 T 28-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A6A12_RS01880 cc180c53aaa0eabf205185f00d18c223 351 ProSitePatterns PS01155 Endonuclease III family signature. 100 129 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 A6A12_RS01880 cc180c53aaa0eabf205185f00d18c223 351 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 165 9.2E-22 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A6A12_RS01880 cc180c53aaa0eabf205185f00d18c223 351 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 4 263 7.5E-128 T 28-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 A6A12_RS01880 cc180c53aaa0eabf205185f00d18c223 351 Pfam PF00633 Helix-hairpin-helix motif 97 125 2.6E-6 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A6A12_RS01880 cc180c53aaa0eabf205185f00d18c223 351 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 190 206 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A6A12_RS01880 cc180c53aaa0eabf205185f00d18c223 351 Gene3D G3DSA:1.10.1670.10 118 223 6.9E-34 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A6A12_RS01880 cc180c53aaa0eabf205185f00d18c223 351 Gene3D G3DSA:3.90.79.10 226 348 2.6E-8 T 28-03-2018 A6A12_RS07715 297c94a19152e20debfeabfa46d65e35 262 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 93 4.8E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS07715 297c94a19152e20debfeabfa46d65e35 262 SUPERFAMILY SSF46894 16 93 9.07E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS07715 297c94a19152e20debfeabfa46d65e35 262 SMART SM00862 18 93 1.0E-11 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS07715 297c94a19152e20debfeabfa46d65e35 262 Gene3D G3DSA:1.10.10.10 1 98 3.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS12965 a30e1397b14ca1affb5c0106f0309212 228 SUPERFAMILY SSF52172 1 123 1.2E-39 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS12965 a30e1397b14ca1affb5c0106f0309212 228 SUPERFAMILY SSF46894 124 225 1.28E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS12965 a30e1397b14ca1affb5c0106f0309212 228 SMART SM00448 2 111 1.3E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS12965 a30e1397b14ca1affb5c0106f0309212 228 Pfam PF00072 Response regulator receiver domain 4 112 2.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS12965 a30e1397b14ca1affb5c0106f0309212 228 Gene3D G3DSA:3.40.50.2300 1 124 1.1E-35 T 28-03-2018 A6A12_RS12965 a30e1397b14ca1affb5c0106f0309212 228 SMART SM00862 148 224 5.1E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS12965 a30e1397b14ca1affb5c0106f0309212 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 3.8E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS12965 a30e1397b14ca1affb5c0106f0309212 228 Gene3D G3DSA:1.10.10.10 125 228 8.1E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05940 36685ee5a86c8f7e1d80dcc64864ff5e 222 Gene3D G3DSA:1.20.1170.10 4 222 3.4E-5 T 28-03-2018 A6A12_RS05940 36685ee5a86c8f7e1d80dcc64864ff5e 222 Pfam PF04012 PspA/IM30 family 2 217 2.1E-58 T 28-03-2018 IPR007157 PspA/IM30 A6A12_RS05940 36685ee5a86c8f7e1d80dcc64864ff5e 222 TIGRFAM TIGR02977 phageshock_pspA: phage shock protein A 1 219 2.1E-93 T 28-03-2018 IPR014319 Phage shock protein, PspA A6A12_RS07155 c2ec87be4353bb750bb0e1b1df49fcb7 467 Gene3D G3DSA:1.20.1250.20 246 465 1.2E-27 T 28-03-2018 A6A12_RS07155 c2ec87be4353bb750bb0e1b1df49fcb7 467 Gene3D G3DSA:1.20.1250.20 7 199 2.9E-27 T 28-03-2018 A6A12_RS07155 c2ec87be4353bb750bb0e1b1df49fcb7 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 389 408 1.2E-7 T 28-03-2018 A6A12_RS07155 c2ec87be4353bb750bb0e1b1df49fcb7 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 107 127 1.2E-7 T 28-03-2018 A6A12_RS07155 c2ec87be4353bb750bb0e1b1df49fcb7 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 1.2E-7 T 28-03-2018 A6A12_RS07155 c2ec87be4353bb750bb0e1b1df49fcb7 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 203 221 1.2E-7 T 28-03-2018 A6A12_RS07155 c2ec87be4353bb750bb0e1b1df49fcb7 467 Pfam PF07690 Major Facilitator Superfamily 19 398 3.7E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A6A12_RS07155 c2ec87be4353bb750bb0e1b1df49fcb7 467 SUPERFAMILY SSF103473 12 200 1.27E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain A6A12_RS07155 c2ec87be4353bb750bb0e1b1df49fcb7 467 SUPERFAMILY SSF103473 243 459 1.27E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain A6A12_RS13445 28673fe2482e792faf95df21c24556c8 260 SUPERFAMILY SSF53448 14 257 1.33E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13445 28673fe2482e792faf95df21c24556c8 260 Pfam PF04488 Glycosyltransferase sugar-binding region containing DXD motif 73 148 5.5E-13 T 28-03-2018 IPR007577 Glycosyltransferase, DXD sugar-binding motif A6A12_RS14260 45c18f61de979d9917411f825486976c 127 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 7 125 18.81 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A6A12_RS14260 45c18f61de979d9917411f825486976c 127 TIGRFAM TIGR00494 crcB: protein CrcB 10 123 4.6E-29 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A6A12_RS14260 45c18f61de979d9917411f825486976c 127 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 9 120 2.9E-23 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1063 1075 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 Gene3D G3DSA:3.90.1800.10 1266 1308 7.6E-12 T 28-03-2018 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 Pfam PF04565 RNA polymerase Rpb2, domain 3 513 580 7.3E-29 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 Gene3D G3DSA:1.20.5.400 942 1025 2.3E-4 T 28-03-2018 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 Gene3D G3DSA:3.90.1100.10 648 713 2.4E-14 T 28-03-2018 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 Gene3D G3DSA:3.90.1100.10 19 647 5.8E-115 T 28-03-2018 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 Gene3D G3DSA:2.40.50.100 715 795 2.3E-27 T 28-03-2018 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 Pfam PF04560 RNA polymerase Rpb2, domain 7 1265 1339 3.0E-27 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 Pfam PF10385 RNA polymerase beta subunit external 1 domain 591 656 6.9E-23 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 SUPERFAMILY SSF64484 343 939 0.0 T 28-03-2018 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 SUPERFAMILY SSF64484 11 226 0.0 T 28-03-2018 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 SUPERFAMILY SSF64484 1039 1341 0.0 T 28-03-2018 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 Gene3D G3DSA:2.40.50.150 814 941 1.0E-29 T 28-03-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1338 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 Pfam PF04561 RNA polymerase Rpb2, domain 2 340 454 2.9E-14 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 Pfam PF04561 RNA polymerase Rpb2, domain 2 151 225 5.3E-8 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 Gene3D G3DSA:2.40.270.10 1026 1241 6.4E-77 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 Pfam PF00562 RNA polymerase Rpb2, domain 6 717 1263 1.8E-157 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1341 12.325 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS01185 58a1385d6d994f1308945969615758ea 1342 Pfam PF04563 RNA polymerase beta subunit 26 500 2.0E-57 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A6A12_RS12435 b0f41beed04e1068af4875f08c0ff325 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12435 b0f41beed04e1068af4875f08c0ff325 130 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 130 30.91 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12435 b0f41beed04e1068af4875f08c0ff325 130 Pfam PF00410 Ribosomal protein S8 5 129 1.4E-46 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12435 b0f41beed04e1068af4875f08c0ff325 130 Gene3D G3DSA:3.30.1490.10 74 129 6.9E-21 T 28-03-2018 A6A12_RS12435 b0f41beed04e1068af4875f08c0ff325 130 Gene3D G3DSA:3.30.1370.30 1 66 7.4E-23 T 28-03-2018 A6A12_RS12435 b0f41beed04e1068af4875f08c0ff325 130 SUPERFAMILY SSF56047 2 129 5.1E-44 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS13550 0e4d0a2edf8931fa5a5466c49c2b8bfb 238 SUPERFAMILY SSF54211 1 181 2.23E-45 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS13550 0e4d0a2edf8931fa5a5466c49c2b8bfb 238 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 28-03-2018 IPR018336 Ribonuclease PH, conserved site A6A12_RS13550 0e4d0a2edf8931fa5a5466c49c2b8bfb 238 Pfam PF03725 3' exoribonuclease family, domain 2 159 224 1.6E-11 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A6A12_RS13550 0e4d0a2edf8931fa5a5466c49c2b8bfb 238 Hamap MF_00564 Ribonuclease PH [rph]. 1 237 48.107 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 A6A12_RS13550 0e4d0a2edf8931fa5a5466c49c2b8bfb 238 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 3.0E-111 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 A6A12_RS13550 0e4d0a2edf8931fa5a5466c49c2b8bfb 238 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 2.5E-26 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A6A12_RS13550 0e4d0a2edf8931fa5a5466c49c2b8bfb 238 SUPERFAMILY SSF55666 153 234 4.06E-26 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A6A12_RS13550 0e4d0a2edf8931fa5a5466c49c2b8bfb 238 Gene3D G3DSA:3.30.230.70 1 238 2.7E-62 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A6A12_RS09110 48b65a08389363e35bab80bcc56f6e0c 179 Gene3D G3DSA:1.20.1550.10 5 178 4.8E-49 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain A6A12_RS09110 48b65a08389363e35bab80bcc56f6e0c 179 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 11 172 21.958 T 28-03-2018 IPR022920 Disulphide bond formation protein DsbB A6A12_RS09110 48b65a08389363e35bab80bcc56f6e0c 179 SUPERFAMILY SSF158442 19 165 3.27E-43 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain A6A12_RS09110 48b65a08389363e35bab80bcc56f6e0c 179 Pfam PF02600 Disulfide bond formation protein DsbB 16 164 3.7E-43 T 28-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 A6A12_RS05140 2cd506e6c5199b795b168abfdf95ac56 484 Gene3D G3DSA:3.30.565.10 355 482 1.2E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS05140 2cd506e6c5199b795b168abfdf95ac56 484 SUPERFAMILY SSF55874 347 481 1.2E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS05140 2cd506e6c5199b795b168abfdf95ac56 484 SMART SM00387 377 482 6.2E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS05140 2cd506e6c5199b795b168abfdf95ac56 484 SMART SM00304 227 279 1.3E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS05140 2cd506e6c5199b795b168abfdf95ac56 484 Gene3D G3DSA:1.10.287.130 270 354 7.3E-8 T 28-03-2018 A6A12_RS05140 2cd506e6c5199b795b168abfdf95ac56 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 460 1.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS05140 2cd506e6c5199b795b168abfdf95ac56 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 425 1.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS05140 2cd506e6c5199b795b168abfdf95ac56 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 439 1.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS05140 2cd506e6c5199b795b168abfdf95ac56 484 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 380 480 7.7E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS05140 2cd506e6c5199b795b168abfdf95ac56 484 SUPERFAMILY SSF47384 264 328 1.92E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS05140 2cd506e6c5199b795b168abfdf95ac56 484 Pfam PF00672 HAMP domain 227 276 1.6E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS02410 7204d32b024e03135e4bfd9245f35c25 312 Pfam PF01476 LysM domain 50 92 6.5E-11 T 28-03-2018 IPR018392 LysM domain A6A12_RS02410 7204d32b024e03135e4bfd9245f35c25 312 Gene3D G3DSA:2.70.70.10 134 312 5.2E-40 T 28-03-2018 A6A12_RS02410 7204d32b024e03135e4bfd9245f35c25 312 SUPERFAMILY SSF54106 49 93 8.5E-10 T 28-03-2018 IPR018392 LysM domain A6A12_RS02410 7204d32b024e03135e4bfd9245f35c25 312 SUPERFAMILY SSF51261 167 311 6.8E-49 T 28-03-2018 IPR011055 Duplicated hybrid motif A6A12_RS02410 7204d32b024e03135e4bfd9245f35c25 312 SMART SM00257 49 93 1.8E-10 T 28-03-2018 IPR018392 LysM domain A6A12_RS02410 7204d32b024e03135e4bfd9245f35c25 312 Gene3D G3DSA:3.10.350.10 43 121 4.1E-11 T 28-03-2018 A6A12_RS02410 7204d32b024e03135e4bfd9245f35c25 312 Pfam PF01551 Peptidase family M23 213 307 1.5E-31 T 28-03-2018 IPR016047 Peptidase M23 A6A12_RS11220 34d73f5963734c75306fc886445d1121 313 Gene3D G3DSA:3.30.460.20 4 126 1.5E-9 T 28-03-2018 A6A12_RS11220 34d73f5963734c75306fc886445d1121 313 Gene3D G3DSA:1.20.58.340 127 244 1.2E-7 T 28-03-2018 A6A12_RS11220 34d73f5963734c75306fc886445d1121 313 SUPERFAMILY SSF144083 244 306 1.96E-13 T 28-03-2018 A6A12_RS11220 34d73f5963734c75306fc886445d1121 313 Gene3D G3DSA:1.20.58.340 245 309 1.9E-13 T 28-03-2018 A6A12_RS11220 34d73f5963734c75306fc886445d1121 313 SUPERFAMILY SSF143865 6 231 1.83E-29 T 28-03-2018 A6A12_RS11220 34d73f5963734c75306fc886445d1121 313 Pfam PF01544 CorA-like Mg2+ transporter protein 29 305 1.0E-51 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A6A12_RS13050 8501a80e5ea7059ffa9e0965aee97390 581 Pfam PF00999 Sodium/hydrogen exchanger family 15 384 3.7E-54 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A6A12_RS13050 8501a80e5ea7059ffa9e0965aee97390 581 Pfam PF03471 Transporter associated domain 495 569 1.2E-5 T 28-03-2018 IPR005170 Transporter-associated domain A6A12_RS13050 8501a80e5ea7059ffa9e0965aee97390 581 Gene3D G3DSA:3.30.70.1450 414 488 9.4E-14 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS13050 8501a80e5ea7059ffa9e0965aee97390 581 Pfam PF02080 TrkA-C domain 420 484 1.2E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS13050 8501a80e5ea7059ffa9e0965aee97390 581 SMART SM01091 493 572 6.5E-7 T 28-03-2018 IPR005170 Transporter-associated domain A6A12_RS13050 8501a80e5ea7059ffa9e0965aee97390 581 Gene3D G3DSA:3.30.465.10 489 574 2.0E-5 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A6A12_RS13050 8501a80e5ea7059ffa9e0965aee97390 581 Hamap MF_01075 K(+)/H(+) antiporter NhaP2 [nhaP2]. 1 575 50.133 T 28-03-2018 IPR023729 K(+)/H(+) antiporter NhaP2 GO:0005451|GO:0006812|GO:0006813|GO:0006884|GO:0016021 A6A12_RS13050 8501a80e5ea7059ffa9e0965aee97390 581 SUPERFAMILY SSF56176 498 569 2.18E-5 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A6A12_RS13050 8501a80e5ea7059ffa9e0965aee97390 581 SUPERFAMILY SSF116726 413 484 1.29E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS07005 4f2952459d0356154f63ae90da91c85b 210 Pfam PF11523 Protein of unknown function (DUF3223) 65 141 2.1E-14 T 28-03-2018 A6A12_RS07005 4f2952459d0356154f63ae90da91c85b 210 Gene3D G3DSA:3.10.450.40 41 148 4.7E-21 T 28-03-2018 A6A12_RS02240 4fee828094dc5d838b40b1e411fc67c2 106 SMART SM00530 31 87 4.8E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A6A12_RS02240 4fee828094dc5d838b40b1e411fc67c2 106 SUPERFAMILY SSF47413 20 86 9.65E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS02240 4fee828094dc5d838b40b1e411fc67c2 106 Gene3D G3DSA:1.10.260.40 10 87 5.7E-10 T 28-03-2018 A6A12_RS02240 4fee828094dc5d838b40b1e411fc67c2 106 Pfam PF13744 Helix-turn-helix domain 19 86 1.2E-15 T 28-03-2018 A6A12_RS03675 6ffdd5268e2e5017829cefa305dbd137 97 TIGRFAM TIGR03578 EF_0831: conserved hypothetical protein EF_0831/AHA_3912 2 96 8.3E-42 T 28-03-2018 IPR020037 Protein of unknown function DUF4312 A6A12_RS03675 6ffdd5268e2e5017829cefa305dbd137 97 Pfam PF14189 Domain of unknown function (DUF4312) 6 88 1.0E-35 T 28-03-2018 IPR020037 Protein of unknown function DUF4312 A6A12_RS03870 a51687fb31918101199e83085b71a357 100 SUPERFAMILY SSF54285 6 82 1.01E-25 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A6A12_RS03870 a51687fb31918101199e83085b71a357 100 Pfam PF03658 RnfH family Ubiquitin 8 90 3.9E-34 T 28-03-2018 IPR005346 RnfH protein A6A12_RS03870 a51687fb31918101199e83085b71a357 100 Gene3D G3DSA:3.10.20.280 2 91 6.1E-35 T 28-03-2018 IPR005346 RnfH protein A6A12_RS03870 a51687fb31918101199e83085b71a357 100 Hamap MF_00460 Protein RnfH [rnfH]. 8 98 25.045 T 28-03-2018 IPR005346 RnfH protein A6A12_RS06045 7f39a105a51ba54b7e1c96385f00e478 428 SUPERFAMILY SSF52540 21 98 1.17E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS06045 7f39a105a51ba54b7e1c96385f00e478 428 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 153 161 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A6A12_RS06045 7f39a105a51ba54b7e1c96385f00e478 428 SMART SM00487 20 229 1.3E-55 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS06045 7f39a105a51ba54b7e1c96385f00e478 428 Gene3D G3DSA:3.40.50.300 7 222 2.7E-57 T 28-03-2018 A6A12_RS06045 7f39a105a51ba54b7e1c96385f00e478 428 Pfam PF00270 DEAD/DEAH box helicase 25 194 6.0E-50 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A6A12_RS06045 7f39a105a51ba54b7e1c96385f00e478 428 Pfam PF00271 Helicase conserved C-terminal domain 231 339 1.0E-28 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS06045 7f39a105a51ba54b7e1c96385f00e478 428 Gene3D G3DSA:3.40.50.300 223 428 1.8E-44 T 28-03-2018 A6A12_RS06045 7f39a105a51ba54b7e1c96385f00e478 428 SUPERFAMILY SSF52540 76 356 7.94E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS06045 7f39a105a51ba54b7e1c96385f00e478 428 SMART SM00490 258 339 3.2E-31 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS03320 a18b7ae4ba39729c11652b053e38973d 241 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 25 239 9.8E-65 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase A6A12_RS03320 a18b7ae4ba39729c11652b053e38973d 241 Gene3D G3DSA:3.60.140.10 1 241 4.1E-94 T 28-03-2018 A6A12_RS03320 a18b7ae4ba39729c11652b053e38973d 241 SUPERFAMILY SSF64438 3 240 1.78E-83 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic A6A12_RS03320 a18b7ae4ba39729c11652b053e38973d 241 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 19 238 1.0E-75 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase A6A12_RS03820 f44826bed2ab8a0f13528c9569aaba2b 306 SUPERFAMILY SSF52980 163 284 2.52E-14 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A6A12_RS03820 f44826bed2ab8a0f13528c9569aaba2b 306 Gene3D G3DSA:3.40.1350.10 149 289 6.9E-23 T 28-03-2018 A6A12_RS03820 f44826bed2ab8a0f13528c9569aaba2b 306 Pfam PF04471 Restriction endonuclease 159 280 3.5E-32 T 28-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 A6A12_RS03820 f44826bed2ab8a0f13528c9569aaba2b 306 Pfam PF14338 Mrr N-terminal domain 5 91 6.4E-31 T 28-03-2018 IPR025745 Restriction system protein Mrr-like N-terminal domain A6A12_RS04375 0eb7a1f16dcdaaeddda01f1e6d18e770 105 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 9.2E-37 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A6A12_RS04375 0eb7a1f16dcdaaeddda01f1e6d18e770 105 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 23.95 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS A6A12_RS04375 0eb7a1f16dcdaaeddda01f1e6d18e770 105 SUPERFAMILY SSF81301 2 105 1.8E-36 T 28-03-2018 A6A12_RS04375 0eb7a1f16dcdaaeddda01f1e6d18e770 105 Gene3D G3DSA:3.30.460.10 1 105 5.4E-33 T 28-03-2018 A6A12_RS04375 0eb7a1f16dcdaaeddda01f1e6d18e770 105 Pfam PF02410 Ribosomal silencing factor during starvation 11 104 3.9E-26 T 28-03-2018 A6A12_RS06630 fe6970913d063947a11b7b42844a998d 709 SUPERFAMILY SSF53335 399 705 4.51E-70 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS06630 fe6970913d063947a11b7b42844a998d 709 Gene3D G3DSA:3.40.50.150 93 366 2.8E-32 T 28-03-2018 A6A12_RS06630 fe6970913d063947a11b7b42844a998d 709 Gene3D G3DSA:3.40.50.150 496 706 2.7E-42 T 28-03-2018 A6A12_RS06630 fe6970913d063947a11b7b42844a998d 709 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 195 206 - T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS06630 fe6970913d063947a11b7b42844a998d 709 Gene3D G3DSA:3.30.750.80 395 495 3.2E-7 T 28-03-2018 A6A12_RS06630 fe6970913d063947a11b7b42844a998d 709 Hamap MF_01858 Ribosomal RNA large subunit methyltransferase K/L [rlmL]. 4 706 31.385 T 28-03-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS06630 fe6970913d063947a11b7b42844a998d 709 PIRSF PIRSF037618 1 707 7.7E-295 T 28-03-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS06630 fe6970913d063947a11b7b42844a998d 709 Pfam PF01170 Putative RNA methylase family UPF0020 162 374 2.1E-57 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS06630 fe6970913d063947a11b7b42844a998d 709 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 305 311 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A6A12_RS06630 fe6970913d063947a11b7b42844a998d 709 SMART SM00981 56 154 5.7E-19 T 28-03-2018 IPR004114 THUMP domain GO:0003723 A6A12_RS06630 fe6970913d063947a11b7b42844a998d 709 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 441 662 1.6E-26 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 A6A12_RS06630 fe6970913d063947a11b7b42844a998d 709 SUPERFAMILY SSF53335 140 217 1.88E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS06630 fe6970913d063947a11b7b42844a998d 709 SUPERFAMILY SSF53335 258 371 1.88E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS06630 fe6970913d063947a11b7b42844a998d 709 Pfam PF02926 THUMP domain 31 153 2.4E-13 T 28-03-2018 IPR004114 THUMP domain GO:0003723 A6A12_RS13045 a15d013e9c01fc18df924a0c4805d101 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 3.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS13045 a15d013e9c01fc18df924a0c4805d101 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 3.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS13045 a15d013e9c01fc18df924a0c4805d101 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 3.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS13045 a15d013e9c01fc18df924a0c4805d101 209 Gene3D G3DSA:1.10.10.10 122 208 1.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS13045 a15d013e9c01fc18df924a0c4805d101 209 Pfam PF00072 Response regulator receiver domain 7 119 4.6E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS13045 a15d013e9c01fc18df924a0c4805d101 209 SMART SM00448 5 119 3.1E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS13045 a15d013e9c01fc18df924a0c4805d101 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS13045 a15d013e9c01fc18df924a0c4805d101 209 SUPERFAMILY SSF52172 4 178 8.02E-25 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS13045 a15d013e9c01fc18df924a0c4805d101 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 6.9E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS13045 a15d013e9c01fc18df924a0c4805d101 209 Gene3D G3DSA:3.40.50.2300 1 121 2.2E-25 T 28-03-2018 A6A12_RS13045 a15d013e9c01fc18df924a0c4805d101 209 SMART SM00421 147 204 7.3E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS03565 c95e8d195e8a8082d23c3b0a0ba856fc 204 Gene3D G3DSA:1.25.40.10 141 203 0.0041 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS03565 c95e8d195e8a8082d23c3b0a0ba856fc 204 SUPERFAMILY SSF48452 90 189 3.37E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS03565 c95e8d195e8a8082d23c3b0a0ba856fc 204 Gene3D G3DSA:1.25.40.10 90 140 2.1E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS03565 c95e8d195e8a8082d23c3b0a0ba856fc 204 Pfam PF09976 Tetratricopeptide repeat-like domain 15 204 4.9E-58 T 28-03-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 A6A12_RS03565 c95e8d195e8a8082d23c3b0a0ba856fc 204 PIRSF PIRSF006170 1 204 1.6E-52 T 28-03-2018 IPR026039 Uncharacterised protein family UPF0070 A6A12_RS06235 88ed6e4cbed42fbf6e3c66914598cedc 598 SUPERFAMILY SSF89000 300 455 1.33E-47 T 28-03-2018 A6A12_RS06235 88ed6e4cbed42fbf6e3c66914598cedc 598 Gene3D G3DSA:2.40.50.100 526 598 1.3E-21 T 28-03-2018 A6A12_RS06235 88ed6e4cbed42fbf6e3c66914598cedc 598 SUPERFAMILY SSF51230 522 597 1.7E-22 T 28-03-2018 IPR011053 Single hybrid motif A6A12_RS06235 88ed6e4cbed42fbf6e3c66914598cedc 598 Pfam PF00682 HMGL-like 10 273 9.5E-65 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A6A12_RS06235 88ed6e4cbed42fbf6e3c66914598cedc 598 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 554 571 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A6A12_RS06235 88ed6e4cbed42fbf6e3c66914598cedc 598 SUPERFAMILY SSF51569 4 303 3.66E-91 T 28-03-2018 A6A12_RS06235 88ed6e4cbed42fbf6e3c66914598cedc 598 Pfam PF00364 Biotin-requiring enzyme 535 597 1.4E-18 T 28-03-2018 IPR000089 Biotin/lipoyl attachment A6A12_RS06235 88ed6e4cbed42fbf6e3c66914598cedc 598 Gene3D G3DSA:1.10.10.60 402 456 2.3E-8 T 28-03-2018 A6A12_RS06235 88ed6e4cbed42fbf6e3c66914598cedc 598 Pfam PF02436 Conserved carboxylase domain 295 494 7.0E-56 T 28-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A6A12_RS06235 88ed6e4cbed42fbf6e3c66914598cedc 598 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 10 594 4.6E-275 T 28-03-2018 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 A6A12_RS06235 88ed6e4cbed42fbf6e3c66914598cedc 598 Gene3D G3DSA:3.20.20.70 1 287 6.9E-78 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS08360 ecd890a79cebc2bc62b3d33a7cfd1c82 1176 Gene3D G3DSA:2.60.40.10 622 818 2.6E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS08360 ecd890a79cebc2bc62b3d33a7cfd1c82 1176 SUPERFAMILY SSF49265 638 708 2.29E-5 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 A6A12_RS08360 ecd890a79cebc2bc62b3d33a7cfd1c82 1176 Pfam PF09327 Domain of unknown function (DUF1983) 1019 1093 6.8E-17 T 28-03-2018 IPR015406 Domain of unknown function DUF1983 A6A12_RS08360 ecd890a79cebc2bc62b3d33a7cfd1c82 1176 Pfam PF13550 Putative phage tail protein 340 498 6.8E-18 T 28-03-2018 IPR032876 Tip attachment protein J A6A12_RS00995 24cd53cc22dbcf2b03ff0d9bb1b18d16 239 SMART SM00862 156 232 3.8E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS00995 24cd53cc22dbcf2b03ff0d9bb1b18d16 239 Gene3D G3DSA:1.10.10.10 129 239 3.1E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS00995 24cd53cc22dbcf2b03ff0d9bb1b18d16 239 SMART SM00448 5 116 5.9E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS00995 24cd53cc22dbcf2b03ff0d9bb1b18d16 239 SUPERFAMILY SSF52172 3 127 1.1E-40 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS00995 24cd53cc22dbcf2b03ff0d9bb1b18d16 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 232 6.4E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS00995 24cd53cc22dbcf2b03ff0d9bb1b18d16 239 SUPERFAMILY SSF46894 132 234 5.67E-27 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS00995 24cd53cc22dbcf2b03ff0d9bb1b18d16 239 Gene3D G3DSA:3.40.50.2300 1 128 5.3E-36 T 28-03-2018 A6A12_RS00995 24cd53cc22dbcf2b03ff0d9bb1b18d16 239 Pfam PF00072 Response regulator receiver domain 7 117 2.3E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS12315 27b067ea485cff95a784dbea5c92b6fd 653 Gene3D G3DSA:3.60.21.10 21 351 8.7E-76 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A6A12_RS12315 27b067ea485cff95a784dbea5c92b6fd 653 ProSitePatterns PS00786 5'-nucleotidase signature 2. 115 126 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS12315 27b067ea485cff95a784dbea5c92b6fd 653 Pfam PF00149 Calcineurin-like phosphoesterase 30 265 6.7E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A6A12_RS12315 27b067ea485cff95a784dbea5c92b6fd 653 SUPERFAMILY SSF56300 23 360 1.21E-85 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A6A12_RS12315 27b067ea485cff95a784dbea5c92b6fd 653 Gene3D G3DSA:3.90.780.10 352 611 2.6E-50 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS12315 27b067ea485cff95a784dbea5c92b6fd 653 PRINTS PR01607 Apyrase family signature 434 457 7.2E-30 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS12315 27b067ea485cff95a784dbea5c92b6fd 653 PRINTS PR01607 Apyrase family signature 536 555 7.2E-30 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS12315 27b067ea485cff95a784dbea5c92b6fd 653 PRINTS PR01607 Apyrase family signature 289 309 7.2E-30 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS12315 27b067ea485cff95a784dbea5c92b6fd 653 PRINTS PR01607 Apyrase family signature 221 238 7.2E-30 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS12315 27b067ea485cff95a784dbea5c92b6fd 653 PRINTS PR01607 Apyrase family signature 28 46 7.2E-30 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS12315 27b067ea485cff95a784dbea5c92b6fd 653 PRINTS PR01607 Apyrase family signature 249 272 7.2E-30 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS12315 27b067ea485cff95a784dbea5c92b6fd 653 Pfam PF02872 5'-nucleotidase, C-terminal domain 362 554 3.4E-19 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS12315 27b067ea485cff95a784dbea5c92b6fd 653 TIGRFAM TIGR01390 CycNucDiestase: 2',3'-cyclic-nucleotide 2'-phosphodiesterase 29 652 0.0 T 28-03-2018 IPR006294 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase GO:0008663|GO:0009117 KEGG: 00230+3.1.4.16+3.1.3.6|KEGG: 00240+3.1.4.16+3.1.3.6 A6A12_RS12315 27b067ea485cff95a784dbea5c92b6fd 653 SUPERFAMILY SSF55816 361 603 3.66E-37 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 A6A12_RS06645 31803e03dcc78ecd6173fd23e9219bae 629 Pfam PF11949 Protein of unknown function (DUF3466) 4 629 6.1E-141 T 28-03-2018 IPR022562 Protein of unknown function DUF3466 A6A12_RS06645 31803e03dcc78ecd6173fd23e9219bae 629 TIGRFAM TIGR03501 GlyGly_CTERM: GlyGly-CTERM domain 610 629 2.1E-5 T 28-03-2018 IPR020008 GlyGly-CTERM domain A6A12_RS01575 9de3482822d56fc1ffaef2e9d39a88a1 480 Gene3D G3DSA:1.20.5.170 321 411 8.6E-5 T 28-03-2018 A6A12_RS01575 9de3482822d56fc1ffaef2e9d39a88a1 480 SUPERFAMILY SSF53067 37 154 1.81E-11 T 28-03-2018 A6A12_RS01575 9de3482822d56fc1ffaef2e9d39a88a1 480 PIRSF PIRSF028153 1 480 1.4E-188 T 28-03-2018 IPR016871 MSHA biogenesis protein, MshI A6A12_RS03570 0e1e4b9ff75129f20d5b3cc2a54cd4aa 386 Gene3D G3DSA:2.140.10.10 185 278 2.5E-11 T 28-03-2018 A6A12_RS03570 0e1e4b9ff75129f20d5b3cc2a54cd4aa 386 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 8 382 5.4E-137 T 28-03-2018 IPR017687 Outer membrane protein assembly factor BamB A6A12_RS03570 0e1e4b9ff75129f20d5b3cc2a54cd4aa 386 SMART SM00564 192 223 87.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A6A12_RS03570 0e1e4b9ff75129f20d5b3cc2a54cd4aa 386 SMART SM00564 242 274 17.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A6A12_RS03570 0e1e4b9ff75129f20d5b3cc2a54cd4aa 386 SMART SM00564 108 138 0.0079 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A6A12_RS03570 0e1e4b9ff75129f20d5b3cc2a54cd4aa 386 SMART SM00564 63 94 2.1E-5 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A6A12_RS03570 0e1e4b9ff75129f20d5b3cc2a54cd4aa 386 SMART SM00564 281 312 10.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A6A12_RS03570 0e1e4b9ff75129f20d5b3cc2a54cd4aa 386 SMART SM00564 147 178 0.014 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A6A12_RS03570 0e1e4b9ff75129f20d5b3cc2a54cd4aa 386 SMART SM00564 322 353 13.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A6A12_RS03570 0e1e4b9ff75129f20d5b3cc2a54cd4aa 386 SUPERFAMILY SSF50998 40 375 1.26E-82 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A6A12_RS03570 0e1e4b9ff75129f20d5b3cc2a54cd4aa 386 Pfam PF13360 PQQ-like domain 76 310 3.0E-55 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat A6A12_RS03570 0e1e4b9ff75129f20d5b3cc2a54cd4aa 386 Gene3D G3DSA:2.140.10.10 279 383 8.3E-15 T 28-03-2018 A6A12_RS03570 0e1e4b9ff75129f20d5b3cc2a54cd4aa 386 Gene3D G3DSA:2.140.10.10 31 184 6.0E-29 T 28-03-2018 A6A12_RS03570 0e1e4b9ff75129f20d5b3cc2a54cd4aa 386 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 3 384 40.895 T 28-03-2018 IPR017687 Outer membrane protein assembly factor BamB A6A12_RS09780 d98790d639874da4fd588e056fcff940 769 Pfam PF00384 Molybdopterin oxidoreductase 106 488 5.4E-23 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A6A12_RS09780 d98790d639874da4fd588e056fcff940 769 Gene3D G3DSA:3.40.50.740 107 284 1.3E-35 T 28-03-2018 A6A12_RS09780 d98790d639874da4fd588e056fcff940 769 Gene3D G3DSA:2.40.40.20 633 762 2.1E-21 T 28-03-2018 A6A12_RS09780 d98790d639874da4fd588e056fcff940 769 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 10 758 7.5E-282 T 28-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 A6A12_RS09780 d98790d639874da4fd588e056fcff940 769 Gene3D G3DSA:3.40.50.740 340 599 3.3E-40 T 28-03-2018 A6A12_RS09780 d98790d639874da4fd588e056fcff940 769 Pfam PF01568 Molydopterin dinucleotide binding domain 645 751 4.1E-11 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A6A12_RS09780 d98790d639874da4fd588e056fcff940 769 SUPERFAMILY SSF50692 635 762 2.26E-17 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain A6A12_RS09780 d98790d639874da4fd588e056fcff940 769 SUPERFAMILY SSF53706 44 628 1.14E-135 T 28-03-2018 A6A12_RS09780 d98790d639874da4fd588e056fcff940 769 PIRSF PIRSF000144 1 762 0.0 T 28-03-2018 A6A12_RS08950 89f83829c7dc8787d3eec5b3ee7edd79 625 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 384 413 2.4E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS08950 89f83829c7dc8787d3eec5b3ee7edd79 625 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 490 519 2.4E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS08950 89f83829c7dc8787d3eec5b3ee7edd79 625 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 461 488 2.4E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS08950 89f83829c7dc8787d3eec5b3ee7edd79 625 SUPERFAMILY SSF58104 314 623 4.97E-60 T 28-03-2018 A6A12_RS08950 89f83829c7dc8787d3eec5b3ee7edd79 625 SMART SM00304 294 348 0.0086 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS08950 89f83829c7dc8787d3eec5b3ee7edd79 625 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 408 590 3.0E-38 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS08950 89f83829c7dc8787d3eec5b3ee7edd79 625 SMART SM00283 360 624 5.1E-46 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS08950 89f83829c7dc8787d3eec5b3ee7edd79 625 Gene3D G3DSA:1.10.287.950 323 410 4.9E-6 T 28-03-2018 A6A12_RS08950 89f83829c7dc8787d3eec5b3ee7edd79 625 Gene3D G3DSA:1.10.287.950 411 610 3.3E-41 T 28-03-2018 A6A12_RS03190 ee576f84e6ccf85a4d56aaef7fd4f58f 311 Pfam PF01687 Riboflavin kinase 184 306 3.4E-37 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 A6A12_RS03190 ee576f84e6ccf85a4d56aaef7fd4f58f 311 SMART SM00904 183 307 3.0E-60 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 A6A12_RS03190 ee576f84e6ccf85a4d56aaef7fd4f58f 311 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 18 55 2.4E-7 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A6A12_RS03190 ee576f84e6ccf85a4d56aaef7fd4f58f 311 Gene3D G3DSA:3.40.50.620 1 179 4.6E-49 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS03190 ee576f84e6ccf85a4d56aaef7fd4f58f 311 Pfam PF06574 FAD synthetase 12 167 1.9E-58 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A6A12_RS03190 ee576f84e6ccf85a4d56aaef7fd4f58f 311 SUPERFAMILY SSF52374 15 175 2.25E-36 T 28-03-2018 A6A12_RS03190 ee576f84e6ccf85a4d56aaef7fd4f58f 311 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 306 7.8E-108 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A6A12_RS03190 ee576f84e6ccf85a4d56aaef7fd4f58f 311 Gene3D G3DSA:2.40.30.30 180 310 2.4E-37 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 A6A12_RS03190 ee576f84e6ccf85a4d56aaef7fd4f58f 311 SUPERFAMILY SSF82114 174 309 1.13E-43 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 A6A12_RS03190 ee576f84e6ccf85a4d56aaef7fd4f58f 311 PIRSF PIRSF004491 1 311 1.6E-106 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 A6A12_RS03125 0707c42a7cf8942da034ca0598f615c4 739 Gene3D G3DSA:1.10.443.10 333 604 0.0018 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS06370 7f75bcb75af24bf32cd4a2d507f56c1f 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 429 2.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS06370 7f75bcb75af24bf32cd4a2d507f56c1f 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 2.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS06370 7f75bcb75af24bf32cd4a2d507f56c1f 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 410 2.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS06370 7f75bcb75af24bf32cd4a2d507f56c1f 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 385 2.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS06370 7f75bcb75af24bf32cd4a2d507f56c1f 433 SMART SM00388 212 277 1.9E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS06370 7f75bcb75af24bf32cd4a2d507f56c1f 433 SUPERFAMILY SSF158472 159 207 3.01E-6 T 28-03-2018 A6A12_RS06370 7f75bcb75af24bf32cd4a2d507f56c1f 433 SMART SM00387 320 432 2.1E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS06370 7f75bcb75af24bf32cd4a2d507f56c1f 433 SMART SM00304 159 211 3.1E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS06370 7f75bcb75af24bf32cd4a2d507f56c1f 433 SUPERFAMILY SSF47384 196 276 6.47E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS06370 7f75bcb75af24bf32cd4a2d507f56c1f 433 Pfam PF00512 His Kinase A (phospho-acceptor) domain 216 275 5.7E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS06370 7f75bcb75af24bf32cd4a2d507f56c1f 433 Gene3D G3DSA:1.10.287.130 202 268 2.9E-10 T 28-03-2018 A6A12_RS06370 7f75bcb75af24bf32cd4a2d507f56c1f 433 Gene3D G3DSA:3.30.565.10 269 432 1.1E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS06370 7f75bcb75af24bf32cd4a2d507f56c1f 433 Pfam PF00672 HAMP domain 161 206 1.2E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS06370 7f75bcb75af24bf32cd4a2d507f56c1f 433 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 324 429 7.5E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS06370 7f75bcb75af24bf32cd4a2d507f56c1f 433 SUPERFAMILY SSF55874 266 430 1.44E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS06970 c6a35ff63517db07ef3cd175393fc3af 357 SUPERFAMILY SSF54593 5 341 1.21E-78 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A6A12_RS06970 c6a35ff63517db07ef3cd175393fc3af 357 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 12 354 9.0E-131 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 A6A12_RS06970 c6a35ff63517db07ef3cd175393fc3af 357 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 6 144 1.0E-55 T 28-03-2018 A6A12_RS06970 c6a35ff63517db07ef3cd175393fc3af 357 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 163 275 4.4E-14 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A6A12_RS06970 c6a35ff63517db07ef3cd175393fc3af 357 Gene3D G3DSA:3.10.180.10 158 355 9.5E-60 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A6A12_RS06970 c6a35ff63517db07ef3cd175393fc3af 357 PIRSF PIRSF009283 1 355 3.6E-125 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 A6A12_RS06970 c6a35ff63517db07ef3cd175393fc3af 357 Gene3D G3DSA:3.10.180.10 2 155 9.8E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A6A12_RS04160 1abffb6f908b958f51cce0b3085a7f8c 472 SUPERFAMILY SSF55604 10 81 5.89E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A6A12_RS04160 1abffb6f908b958f51cce0b3085a7f8c 472 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 6 459 4.8E-203 T 28-03-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00230+2.7.1.20|KEGG: 00500+2.7.1.201|MetaCyc: PWY-6619 A6A12_RS04160 1abffb6f908b958f51cce0b3085a7f8c 472 Pfam PF02378 Phosphotransferase system, EIIC 112 404 5.1E-33 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A6A12_RS04160 1abffb6f908b958f51cce0b3085a7f8c 472 Pfam PF00367 phosphotransferase system, EIIB 12 43 1.5E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A6A12_RS04160 1abffb6f908b958f51cce0b3085a7f8c 472 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A6A12_RS04160 1abffb6f908b958f51cce0b3085a7f8c 472 Gene3D G3DSA:3.30.1360.60 5 78 2.5E-25 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A6A12_RS04160 1abffb6f908b958f51cce0b3085a7f8c 472 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 30 111 4.6E-16 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A6A12_RS03260 e1d172cd77cddaef119679d13608c95c 375 SMART SM00830 9 89 8.3E-29 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A6A12_RS03260 e1d172cd77cddaef119679d13608c95c 375 Gene3D G3DSA:1.10.3660.10 249 372 3.8E-29 T 28-03-2018 A6A12_RS03260 e1d172cd77cddaef119679d13608c95c 375 SUPERFAMILY SSF48179 241 366 1.81E-38 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 A6A12_RS03260 e1d172cd77cddaef119679d13608c95c 375 SUPERFAMILY SSF51735 91 237 2.01E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS03260 e1d172cd77cddaef119679d13608c95c 375 TIGRFAM TIGR01799 CM_T: chorismate mutase 5 87 8.1E-41 T 28-03-2018 IPR011277 Chorismate mutase, T-protein GO:0004106|GO:0005737|GO:0006571|GO:0055114 KEGG: 00400+5.4.99.5+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7303|MetaCyc: PWY-7626 A6A12_RS03260 e1d172cd77cddaef119679d13608c95c 375 Gene3D G3DSA:1.20.59.10 2 91 2.0E-26 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A6A12_RS03260 e1d172cd77cddaef119679d13608c95c 375 Gene3D G3DSA:3.40.50.720 92 247 4.6E-22 T 28-03-2018 A6A12_RS03260 e1d172cd77cddaef119679d13608c95c 375 Pfam PF01817 Chorismate mutase type II 9 87 6.7E-21 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A6A12_RS03260 e1d172cd77cddaef119679d13608c95c 375 PIRSF PIRSF001499 1 374 1.8E-178 T 28-03-2018 IPR008244 Bifunctional chorismate mutase/prephenate dehydrogenase T-protein GO:0004106|GO:0005737|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+5.4.99.5+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7303|MetaCyc: PWY-7626 A6A12_RS03260 e1d172cd77cddaef119679d13608c95c 375 SUPERFAMILY SSF48600 3 87 1.04E-23 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 A6A12_RS03260 e1d172cd77cddaef119679d13608c95c 375 Pfam PF02153 Prephenate dehydrogenase 130 343 9.4E-28 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 SUPERFAMILY SSF81301 27 172 1.38E-19 T 28-03-2018 A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 Pfam PF08335 GlnD PII-uridylyltransferase 176 314 8.5E-35 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 Gene3D G3DSA:3.30.460.10 39 169 1.7E-24 T 28-03-2018 A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 PIRSF PIRSF006288 7 874 0.0 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 Pfam PF01909 Nucleotidyltransferase domain 67 107 1.8E-7 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 SUPERFAMILY SSF55021 689 747 2.89E-8 T 28-03-2018 A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 Gene3D G3DSA:1.20.120.330 174 316 6.4E-23 T 28-03-2018 A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 SUPERFAMILY SSF55021 796 852 2.11E-9 T 28-03-2018 A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 SUPERFAMILY SSF109604 416 583 1.69E-13 T 28-03-2018 A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 874 333.27 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 Gene3D G3DSA:3.30.70.260 681 778 5.5E-8 T 28-03-2018 A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 Gene3D G3DSA:3.30.70.260 793 871 4.5E-10 T 28-03-2018 A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 SMART SM00471 447 594 6.2E-7 T 28-03-2018 IPR003607 HD/PDEase domain A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 Pfam PF01966 HD domain 452 584 7.0E-11 T 28-03-2018 IPR006674 HD domain A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 SUPERFAMILY SSF81593 200 310 1.1E-8 T 28-03-2018 A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 Gene3D G3DSA:1.10.3090.10 373 635 5.2E-41 T 28-03-2018 A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 Pfam PF01842 ACT domain 804 844 2.1E-6 T 28-03-2018 IPR002912 ACT domain A6A12_RS10920 ebcc629f7d2e5f890c0478bf0817e06a 874 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 28 868 0.0 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 A6A12_RS07375 6749b88d3faad1f0b66e5e32327c4ff9 119 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 4 96 1.3E-33 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 A6A12_RS07375 6749b88d3faad1f0b66e5e32327c4ff9 119 PIRSF PIRSF006113 1 119 2.3E-53 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 A6A12_RS07375 6749b88d3faad1f0b66e5e32327c4ff9 119 SUPERFAMILY SSF55620 1 118 4.45E-42 T 28-03-2018 A6A12_RS07375 6749b88d3faad1f0b66e5e32327c4ff9 119 Gene3D G3DSA:3.30.479.10 1 119 3.2E-42 T 28-03-2018 A6A12_RS07375 6749b88d3faad1f0b66e5e32327c4ff9 119 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 5 118 1.1E-35 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 A6A12_RS12490 0f96894dad346c7176afd5fc11d36f8b 274 PIRSF PIRSF002158 13 274 9.0E-100 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12490 0f96894dad346c7176afd5fc11d36f8b 274 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 3.6E-56 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A6A12_RS12490 0f96894dad346c7176afd5fc11d36f8b 274 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 1.6E-129 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 A6A12_RS12490 0f96894dad346c7176afd5fc11d36f8b 274 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.102 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 A6A12_RS12490 0f96894dad346c7176afd5fc11d36f8b 274 Gene3D G3DSA:4.10.950.10 197 273 1.8E-36 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 A6A12_RS12490 0f96894dad346c7176afd5fc11d36f8b 274 SMART SM01383 42 118 1.6E-46 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12490 0f96894dad346c7176afd5fc11d36f8b 274 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12490 0f96894dad346c7176afd5fc11d36f8b 274 Gene3D G3DSA:2.40.50.140 1 114 2.3E-47 T 28-03-2018 A6A12_RS12490 0f96894dad346c7176afd5fc11d36f8b 274 SMART SM01382 124 252 5.2E-92 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A6A12_RS12490 0f96894dad346c7176afd5fc11d36f8b 274 SUPERFAMILY SSF50249 2 125 6.51E-50 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS12490 0f96894dad346c7176afd5fc11d36f8b 274 SUPERFAMILY SSF50104 127 272 7.22E-61 T 28-03-2018 IPR008991 Translation protein SH3-like domain A6A12_RS12490 0f96894dad346c7176afd5fc11d36f8b 274 Gene3D G3DSA:2.30.30.30 119 195 1.2E-30 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 A6A12_RS12490 0f96894dad346c7176afd5fc11d36f8b 274 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 9.4E-34 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS06100 9c4b396e663c98f6a46f0f0c2fc82704 497 Gene3D G3DSA:3.30.530.20 345 495 7.4E-4 T 28-03-2018 IPR023393 START-like domain A6A12_RS06100 9c4b396e663c98f6a46f0f0c2fc82704 497 Pfam PF13460 NAD(P)H-binding 28 167 1.3E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS06100 9c4b396e663c98f6a46f0f0c2fc82704 497 SUPERFAMILY SSF51735 21 311 2.25E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS06100 9c4b396e663c98f6a46f0f0c2fc82704 497 Pfam PF11066 Protein of unknown function (DUF2867) 352 485 9.3E-14 T 28-03-2018 IPR021295 Protein of unknown function DUF2867 A6A12_RS06100 9c4b396e663c98f6a46f0f0c2fc82704 497 Gene3D G3DSA:3.40.50.720 20 327 4.0E-23 T 28-03-2018 A6A12_RS11815 69447507f9651b27a9430610d4f56625 156 PIRSF PIRSF004923 1 156 2.9E-39 T 28-03-2018 IPR026268 Protein RseC A6A12_RS11815 69447507f9651b27a9430610d4f56625 156 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 16 149 3.0E-33 T 28-03-2018 IPR007359 Positive regulator of sigma(E), RseC/MucC A6A12_RS11905 fe8d7a629b7b9be5211f639615faba87 164 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 159 1.4E-62 T 28-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A6A12_RS11905 fe8d7a629b7b9be5211f639615faba87 164 Pfam PF10369 Small subunit of acetolactate synthase 84 158 1.3E-25 T 28-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 A6A12_RS11905 fe8d7a629b7b9be5211f639615faba87 164 Gene3D G3DSA:3.30.70.1150 88 161 6.3E-27 T 28-03-2018 A6A12_RS11905 fe8d7a629b7b9be5211f639615faba87 164 SUPERFAMILY SSF55021 79 162 6.99E-27 T 28-03-2018 A6A12_RS11905 fe8d7a629b7b9be5211f639615faba87 164 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 75 3.0E-35 T 28-03-2018 A6A12_RS11905 fe8d7a629b7b9be5211f639615faba87 164 Pfam PF13710 ACT domain 12 73 3.5E-16 T 28-03-2018 A6A12_RS11905 fe8d7a629b7b9be5211f639615faba87 164 SUPERFAMILY SSF55021 1 75 4.97E-22 T 28-03-2018 A6A12_RS11905 fe8d7a629b7b9be5211f639615faba87 164 Gene3D G3DSA:3.30.70.260 1 87 4.2E-24 T 28-03-2018 A6A12_RS14180 e6250ad0ba78d44785fd281430df65e4 141 PIRSF PIRSF006276 1 141 4.2E-52 T 28-03-2018 IPR006015 Universal stress protein A A6A12_RS14180 e6250ad0ba78d44785fd281430df65e4 141 Gene3D G3DSA:3.40.50.620 2 141 2.7E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS14180 e6250ad0ba78d44785fd281430df65e4 141 SUPERFAMILY SSF52402 3 139 4.69E-32 T 28-03-2018 A6A12_RS14180 e6250ad0ba78d44785fd281430df65e4 141 Pfam PF00582 Universal stress protein family 3 138 6.2E-21 T 28-03-2018 IPR006016 UspA GO:0006950 A6A12_RS06220 a353e30363652acfe3d40c51ad5d5fe1 363 Pfam PF08218 Citrate lyase ligase C-terminal domain 147 333 5.2E-82 T 28-03-2018 IPR013166 Citrate lyase ligase, C-terminal GO:0008771 A6A12_RS06220 a353e30363652acfe3d40c51ad5d5fe1 363 SUPERFAMILY SSF52374 146 334 2.6E-25 T 28-03-2018 A6A12_RS06220 a353e30363652acfe3d40c51ad5d5fe1 363 Gene3D G3DSA:3.40.630.30 14 114 1.8E-9 T 28-03-2018 A6A12_RS06220 a353e30363652acfe3d40c51ad5d5fe1 363 Pfam PF13673 Acetyltransferase (GNAT) domain 36 111 7.0E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A6A12_RS06220 a353e30363652acfe3d40c51ad5d5fe1 363 SMART SM00764 147 333 3.3E-129 T 28-03-2018 IPR013166 Citrate lyase ligase, C-terminal GO:0008771 A6A12_RS06220 a353e30363652acfe3d40c51ad5d5fe1 363 TIGRFAM TIGR00124 cit_ly_ligase: [citrate (pro-3S)-lyase] ligase 7 335 1.1E-141 T 28-03-2018 IPR005216 Citrate lyase ligase GO:0008771 A6A12_RS06220 a353e30363652acfe3d40c51ad5d5fe1 363 PIRSF PIRSF005751 1 350 4.4E-135 T 28-03-2018 IPR005216 Citrate lyase ligase GO:0008771 A6A12_RS06220 a353e30363652acfe3d40c51ad5d5fe1 363 Gene3D G3DSA:3.40.50.620 125 337 2.4E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS06220 a353e30363652acfe3d40c51ad5d5fe1 363 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 147 204 1.8E-12 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A6A12_RS06220 a353e30363652acfe3d40c51ad5d5fe1 363 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 113 338 2.0E-74 T 28-03-2018 A6A12_RS06220 a353e30363652acfe3d40c51ad5d5fe1 363 SUPERFAMILY SSF55729 35 115 2.84E-11 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS06955 474f135d9d1e0b45e33d7490007b3c60 216 Gene3D G3DSA:1.20.1050.10 102 216 5.3E-24 T 28-03-2018 A6A12_RS06955 474f135d9d1e0b45e33d7490007b3c60 216 Pfam PF13417 Glutathione S-transferase, N-terminal domain 6 83 1.3E-15 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 A6A12_RS06955 474f135d9d1e0b45e33d7490007b3c60 216 SUPERFAMILY SSF52833 2 88 9.24E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS06955 474f135d9d1e0b45e33d7490007b3c60 216 SUPERFAMILY SSF47616 86 214 1.99E-29 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like A6A12_RS06955 474f135d9d1e0b45e33d7490007b3c60 216 Gene3D G3DSA:3.40.30.10 1 101 9.8E-26 T 28-03-2018 A6A12_RS06955 474f135d9d1e0b45e33d7490007b3c60 216 Pfam PF14497 Glutathione S-transferase, C-terminal domain 133 202 8.3E-6 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal A6A12_RS06955 474f135d9d1e0b45e33d7490007b3c60 216 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 5 214 9.9E-88 T 28-03-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 A6A12_RS10745 11237aa317cd75bf49b7478a98030893 214 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 8 214 4.2E-91 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A6A12_RS10745 11237aa317cd75bf49b7478a98030893 214 Gene3D G3DSA:3.40.50.2020 7 212 7.3E-58 T 28-03-2018 A6A12_RS10745 11237aa317cd75bf49b7478a98030893 214 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 8 214 44.451 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A6A12_RS10745 11237aa317cd75bf49b7478a98030893 214 Pfam PF14681 Uracil phosphoribosyltransferase 13 213 3.5E-64 T 28-03-2018 A6A12_RS10745 11237aa317cd75bf49b7478a98030893 214 SUPERFAMILY SSF53271 9 212 1.66E-66 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A6A12_RS01360 bfd9ea52df7b36e6da15eae98db719ec 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 2.6E-70 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01360 bfd9ea52df7b36e6da15eae98db719ec 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 6.8E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS01360 bfd9ea52df7b36e6da15eae98db719ec 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 6.8E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS01360 bfd9ea52df7b36e6da15eae98db719ec 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 6.8E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS01360 bfd9ea52df7b36e6da15eae98db719ec 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 6.8E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS01360 bfd9ea52df7b36e6da15eae98db719ec 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 6.8E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS01360 bfd9ea52df7b36e6da15eae98db719ec 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 6.8E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS01360 bfd9ea52df7b36e6da15eae98db719ec 124 PIRSF PIRSF002133 1 124 3.1E-54 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS01360 bfd9ea52df7b36e6da15eae98db719ec 124 Gene3D G3DSA:2.40.50.140 1 124 1.3E-63 T 28-03-2018 A6A12_RS01360 bfd9ea52df7b36e6da15eae98db719ec 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS01360 bfd9ea52df7b36e6da15eae98db719ec 124 Pfam PF00164 Ribosomal protein S12/S23 14 123 2.2E-42 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS01360 bfd9ea52df7b36e6da15eae98db719ec 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.514 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01360 bfd9ea52df7b36e6da15eae98db719ec 124 SUPERFAMILY SSF50249 3 123 5.48E-52 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS06755 e58c8712b832a75dae6b4a7c1c8891d9 268 Gene3D G3DSA:1.10.530.10 86 265 6.5E-24 T 28-03-2018 A6A12_RS06755 e58c8712b832a75dae6b4a7c1c8891d9 268 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 126 263 1.4E-17 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 A6A12_RS12820 852d392c2627e5b92b7ecd73276c6825 340 Pfam PF04055 Radical SAM superfamily 117 247 3.1E-9 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A6A12_RS12820 852d392c2627e5b92b7ecd73276c6825 340 Pfam PF13353 4Fe-4S single cluster domain 114 182 4.9E-7 T 28-03-2018 A6A12_RS12820 852d392c2627e5b92b7ecd73276c6825 340 TIGRFAM TIGR00238 TIGR00238: KamA family protein 13 328 2.7E-126 T 28-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase A6A12_RS12820 852d392c2627e5b92b7ecd73276c6825 340 TIGRFAM TIGR03821 EFP_modif_epmB: EF-P beta-lysylation protein EpmB 16 335 6.8E-156 T 28-03-2018 IPR022462 Lysine-2,3-aminomutase-like A6A12_RS12820 852d392c2627e5b92b7ecd73276c6825 340 Gene3D G3DSA:3.20.20.70 98 329 3.9E-16 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS12820 852d392c2627e5b92b7ecd73276c6825 340 SUPERFAMILY SSF102114 102 324 4.84E-26 T 28-03-2018 A6A12_RS12820 852d392c2627e5b92b7ecd73276c6825 340 PIRSF PIRSF004911 3 340 4.4E-114 T 28-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 SUPERFAMILY SSF81923 14 121 4.71E-10 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 13 857 0.0 T 28-03-2018 IPR017729 Type VI secretion system, ATPase ClpV1 A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 Gene3D G3DSA:1.10.8.60 774 868 5.0E-12 T 28-03-2018 A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 SMART SM00382 603 750 1.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 SMART SM00382 214 359 6.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 Gene3D G3DSA:3.40.50.300 173 358 7.4E-21 T 28-03-2018 A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 SMART SM01086 773 865 2.6E-9 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 Pfam PF07724 AAA domain (Cdc48 subfamily) 602 767 7.2E-39 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 607 625 8.4E-29 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 670 8.4E-29 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 681 699 8.4E-29 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 714 728 8.4E-29 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 351 9.2E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 773 847 8.1E-12 T 28-03-2018 IPR019489 Clp ATPase, C-terminal A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 Gene3D G3DSA:3.40.50.300 569 773 3.0E-28 T 28-03-2018 A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 SUPERFAMILY SSF52540 552 843 1.99E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 SUPERFAMILY SSF52540 175 500 1.93E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 Gene3D G3DSA:1.10.8.60 360 553 6.4E-36 T 28-03-2018 A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 Gene3D G3DSA:1.10.1780.10 2 161 2.0E-12 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 A6A12_RS07795 bc3d56aab37dfef9b7343afff6f2594d 868 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 310 322 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 SUPERFAMILY SSF49373 566 642 1.57E-6 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 SUPERFAMILY SSF49373 306 387 1.33E-7 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 SUPERFAMILY SSF49373 480 562 1.02E-7 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 SMART SM00635 480 561 8.5E-12 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 SMART SM00635 393 474 2.2E-12 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 SMART SM00635 306 387 1.3E-12 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 SMART SM00635 219 300 2.7E-7 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 SMART SM00635 566 646 3.2E-10 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 SMART SM00635 132 213 1.7E-9 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 SUPERFAMILY SSF49373 393 467 6.2E-7 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 Pfam PF02368 Bacterial Ig-like domain (group 2) 567 638 7.2E-12 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 Pfam PF02368 Bacterial Ig-like domain (group 2) 133 207 1.1E-9 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 Pfam PF02368 Bacterial Ig-like domain (group 2) 307 379 1.3E-13 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 Pfam PF02368 Bacterial Ig-like domain (group 2) 220 298 1.7E-10 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 Pfam PF02368 Bacterial Ig-like domain (group 2) 481 562 1.9E-12 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 Pfam PF02368 Bacterial Ig-like domain (group 2) 394 475 3.8E-13 T 28-03-2018 IPR003343 Bacterial Ig-like, group 2 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 SUPERFAMILY SSF49373 220 302 2.35E-6 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 Gene3D G3DSA:2.60.40.1080 130 216 4.4E-14 T 28-03-2018 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 Gene3D G3DSA:2.60.40.1080 217 303 5.0E-15 T 28-03-2018 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 Gene3D G3DSA:2.60.40.1080 33 129 1.7E-10 T 28-03-2018 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 Gene3D G3DSA:2.60.40.1080 304 390 1.1E-15 T 28-03-2018 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 Gene3D G3DSA:2.60.40.1080 391 477 2.4E-15 T 28-03-2018 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 Gene3D G3DSA:2.60.40.1080 478 563 6.7E-17 T 28-03-2018 A6A12_RS02050 dcec2002bb531174725e6284771acdd2 800 Gene3D G3DSA:2.60.40.1080 564 651 6.9E-14 T 28-03-2018 A6A12_RS07370 c25b549c3ea4a784f25bfb1fc1d15903 399 Pfam PF04231 Endonuclease I 155 391 3.3E-100 T 28-03-2018 IPR007346 Endonuclease I GO:0004518 A6A12_RS07370 c25b549c3ea4a784f25bfb1fc1d15903 399 SUPERFAMILY SSF54060 153 391 2.59E-51 T 28-03-2018 A6A12_RS03315 dc1bd881eaa8fdc055d99f52dce7e210 324 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS03315 dc1bd881eaa8fdc055d99f52dce7e210 324 SMART SM00363 18 83 1.8E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS03315 dc1bd881eaa8fdc055d99f52dce7e210 324 SUPERFAMILY SSF55120 77 317 1.97E-79 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS03315 dc1bd881eaa8fdc055d99f52dce7e210 324 Gene3D G3DSA:3.30.2350.10 83 316 2.0E-68 T 28-03-2018 A6A12_RS03315 dc1bd881eaa8fdc055d99f52dce7e210 324 Pfam PF00849 RNA pseudouridylate synthase 93 241 1.8E-31 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS03315 dc1bd881eaa8fdc055d99f52dce7e210 324 Gene3D G3DSA:3.10.290.10 2 76 5.4E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS03315 dc1bd881eaa8fdc055d99f52dce7e210 324 SUPERFAMILY SSF55174 17 69 2.86E-11 T 28-03-2018 A6A12_RS03315 dc1bd881eaa8fdc055d99f52dce7e210 324 Pfam PF01479 S4 domain 18 65 2.7E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS03315 dc1bd881eaa8fdc055d99f52dce7e210 324 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 15 313 1.2E-106 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS07935 19c4a6c08c2558b0b383d3f56a668b23 324 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 34 270 7.5E-12 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A6A12_RS07935 19c4a6c08c2558b0b383d3f56a668b23 324 SUPERFAMILY SSF111369 41 123 3.92E-7 T 28-03-2018 A6A12_RS07935 19c4a6c08c2558b0b383d3f56a668b23 324 Gene3D G3DSA:2.40.50.100 42 140 7.5E-12 T 28-03-2018 A6A12_RS07935 19c4a6c08c2558b0b383d3f56a668b23 324 Gene3D G3DSA:2.40.50.100 162 241 9.4E-6 T 28-03-2018 A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 285 293 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 264 280 2.1E-86 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 229 258 2.1E-86 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 100 127 2.1E-86 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 59 81 2.1E-86 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 281 299 2.1E-86 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 180 200 2.1E-86 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 135 156 2.1E-86 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 31 146 2.9E-38 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 SUPERFAMILY SSF51735 148 307 1.11E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 Hamap MF_01576 Bifunctional protein FolD [folD]. 28 308 37.502 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 101 126 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 SUPERFAMILY SSF53223 26 147 3.64E-39 T 28-03-2018 A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 149 306 1.3E-67 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 Gene3D G3DSA:3.40.50.10860 36 165 4.3E-48 T 28-03-2018 A6A12_RS05075 b02cdac796e2b27f6eb8fa6e0a16f6cf 311 Gene3D G3DSA:3.40.50.720 166 289 7.4E-39 T 28-03-2018 A6A12_RS06280 367ffbcfb6df60241cfdef88416eca1f 257 Gene3D G3DSA:3.90.850.10 1 111 0.033 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A6A12_RS07415 b978728ff6093daf8b21c95b0c282b74 539 Gene3D G3DSA:1.10.287.1060 235 320 1.7E-5 T 28-03-2018 A6A12_RS07415 b978728ff6093daf8b21c95b0c282b74 539 SUPERFAMILY SSF58104 232 499 1.23E-65 T 28-03-2018 A6A12_RS07415 b978728ff6093daf8b21c95b0c282b74 539 Gene3D G3DSA:1.10.287.950 321 502 2.3E-46 T 28-03-2018 A6A12_RS07415 b978728ff6093daf8b21c95b0c282b74 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 356 383 5.9E-32 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07415 b978728ff6093daf8b21c95b0c282b74 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 279 308 5.9E-32 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07415 b978728ff6093daf8b21c95b0c282b74 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 385 414 5.9E-32 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07415 b978728ff6093daf8b21c95b0c282b74 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 5.9E-32 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07415 b978728ff6093daf8b21c95b0c282b74 539 SMART SM00283 265 498 2.6E-69 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS07415 b978728ff6093daf8b21c95b0c282b74 539 SMART SM00304 212 264 2.0E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS07415 b978728ff6093daf8b21c95b0c282b74 539 Gene3D G3DSA:1.20.120.30 23 186 1.0E-26 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain A6A12_RS07415 b978728ff6093daf8b21c95b0c282b74 539 Pfam PF02203 Tar ligand binding domain homologue 1 174 3.1E-36 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 A6A12_RS07415 b978728ff6093daf8b21c95b0c282b74 539 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 484 2.6E-32 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS08100 89adc01bac51f1bd3b3ea42058aafca4 295 PIRSF PIRSF006334 14 295 1.7E-104 T 28-03-2018 A6A12_RS08100 89adc01bac51f1bd3b3ea42058aafca4 295 SUPERFAMILY SSF53927 152 282 3.01E-35 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A6A12_RS08100 89adc01bac51f1bd3b3ea42058aafca4 295 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 60 141 3.8E-13 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A6A12_RS08100 89adc01bac51f1bd3b3ea42058aafca4 295 TIGRFAM TIGR01355 cyt_deam_dimer: cytidine deaminase 29 293 2.0E-100 T 28-03-2018 IPR006263 Cytidine deaminase, homodimeric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 A6A12_RS08100 89adc01bac51f1bd3b3ea42058aafca4 295 Gene3D G3DSA:3.40.140.10 181 288 5.5E-14 T 28-03-2018 A6A12_RS08100 89adc01bac51f1bd3b3ea42058aafca4 295 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 102 136 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A6A12_RS08100 89adc01bac51f1bd3b3ea42058aafca4 295 SUPERFAMILY SSF53927 1 146 6.69E-41 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A6A12_RS08100 89adc01bac51f1bd3b3ea42058aafca4 295 Gene3D G3DSA:3.40.140.10 40 171 4.6E-28 T 28-03-2018 A6A12_RS08100 89adc01bac51f1bd3b3ea42058aafca4 295 Pfam PF08211 Cytidine and deoxycytidylate deaminase zinc-binding region 157 277 4.4E-41 T 28-03-2018 IPR013171 Cytidine/deoxycytidylate deaminase, zinc-binding domain GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 A6A12_RS08100 89adc01bac51f1bd3b3ea42058aafca4 295 Hamap MF_01558 Cytidine deaminase [cdd]. 1 293 48.427 T 28-03-2018 IPR020797 Cytidine deaminase, bacteria GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 A6A12_RS00545 22dd3c565ebbafd16f4cadddcce13332 224 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 3.7E-90 T 28-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 A6A12_RS00545 22dd3c565ebbafd16f4cadddcce13332 224 SMART SM00382 27 215 5.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS00545 22dd3c565ebbafd16f4cadddcce13332 224 Pfam PF00005 ABC transporter 18 165 3.0E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS00545 22dd3c565ebbafd16f4cadddcce13332 224 SUPERFAMILY SSF52540 1 220 6.28E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS00545 22dd3c565ebbafd16f4cadddcce13332 224 Gene3D G3DSA:3.40.50.300 1 223 1.2E-60 T 28-03-2018 A6A12_RS00545 22dd3c565ebbafd16f4cadddcce13332 224 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS13985 82f1b58f93d37730a663d9aad292a3fd 135 SUPERFAMILY SSF46626 58 131 5.18E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS13985 82f1b58f93d37730a663d9aad292a3fd 135 Gene3D G3DSA:1.10.760.10 56 133 6.4E-10 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS13985 82f1b58f93d37730a663d9aad292a3fd 135 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 57 131 1.2E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS13985 82f1b58f93d37730a663d9aad292a3fd 135 PRINTS PR00607 Class IE cytochrome C signature 121 132 1.0E-15 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 A6A12_RS13985 82f1b58f93d37730a663d9aad292a3fd 135 PRINTS PR00607 Class IE cytochrome C signature 78 88 1.0E-15 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 A6A12_RS13985 82f1b58f93d37730a663d9aad292a3fd 135 PRINTS PR00607 Class IE cytochrome C signature 67 78 1.0E-15 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 A6A12_RS13985 82f1b58f93d37730a663d9aad292a3fd 135 PRINTS PR00607 Class IE cytochrome C signature 106 118 1.0E-15 T 28-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 A6A12_RS02065 1c88b52d81ea5ae6265ac3125fb7a3c1 172 SUPERFAMILY SSF141452 3 169 1.57E-37 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp A6A12_RS02065 1c88b52d81ea5ae6265ac3125fb7a3c1 172 Gene3D G3DSA:2.30.110.20 2 172 2.7E-49 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp A6A12_RS02065 1c88b52d81ea5ae6265ac3125fb7a3c1 172 Pfam PF05638 Type VI secretion system effector, Hcp 6 155 1.8E-31 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp A6A12_RS02065 1c88b52d81ea5ae6265ac3125fb7a3c1 172 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 1 168 6.1E-63 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp A6A12_RS06490 d09e687313b4649d18f1b937153a1c8b 104 ProSitePatterns PS00150 Acylphosphatase signature 1. 22 32 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A6A12_RS06490 d09e687313b4649d18f1b937153a1c8b 104 Pfam PF00708 Acylphosphatase 19 103 1.5E-24 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A6A12_RS06490 d09e687313b4649d18f1b937153a1c8b 104 Gene3D G3DSA:3.30.70.100 10 104 6.7E-27 T 28-03-2018 A6A12_RS06490 d09e687313b4649d18f1b937153a1c8b 104 SUPERFAMILY SSF54975 14 103 1.77E-25 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A6A12_RS06490 d09e687313b4649d18f1b937153a1c8b 104 ProSitePatterns PS00151 Acylphosphatase signature 2. 46 62 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A6A12_RS01215 aa0b994b88121e5e732e1e723bb6261a 320 SUPERFAMILY SSF64182 4 318 1.1E-40 T 28-03-2018 A6A12_RS13035 13c2dfbf4d0cfdb06380c6ed963a347f 152 Pfam PF01316 Arginine repressor, DNA binding domain 10 71 2.9E-14 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 A6A12_RS13035 13c2dfbf4d0cfdb06380c6ed963a347f 152 Pfam PF02863 Arginine repressor, C-terminal domain 84 141 9.8E-17 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A6A12_RS13035 13c2dfbf4d0cfdb06380c6ed963a347f 152 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 127 9.0E-14 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A6A12_RS13035 13c2dfbf4d0cfdb06380c6ed963a347f 152 Hamap MF_00173 Arginine repressor [argR]. 1 152 42.617 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A6A12_RS13035 13c2dfbf4d0cfdb06380c6ed963a347f 152 SUPERFAMILY SSF55252 82 145 4.32E-16 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A6A12_RS13035 13c2dfbf4d0cfdb06380c6ed963a347f 152 SUPERFAMILY SSF46785 4 72 6.17E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS13035 13c2dfbf4d0cfdb06380c6ed963a347f 152 PRINTS PR01467 Bacterial arginine repressor signature 23 36 1.3E-17 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A6A12_RS13035 13c2dfbf4d0cfdb06380c6ed963a347f 152 PRINTS PR01467 Bacterial arginine repressor signature 88 101 1.3E-17 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A6A12_RS13035 13c2dfbf4d0cfdb06380c6ed963a347f 152 PRINTS PR01467 Bacterial arginine repressor signature 40 55 1.3E-17 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A6A12_RS13035 13c2dfbf4d0cfdb06380c6ed963a347f 152 PRINTS PR01467 Bacterial arginine repressor signature 118 133 1.3E-17 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A6A12_RS13035 13c2dfbf4d0cfdb06380c6ed963a347f 152 Gene3D G3DSA:3.30.1360.40 74 152 1.2E-19 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 A6A12_RS13035 13c2dfbf4d0cfdb06380c6ed963a347f 152 Gene3D G3DSA:1.10.10.10 6 67 3.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03760 6129f53017c8d5fb039b36465fec2a51 867 Gene3D G3DSA:3.10.350.10 342 456 4.2E-9 T 28-03-2018 A6A12_RS03760 6129f53017c8d5fb039b36465fec2a51 867 SMART SM00257 375 427 2.1E-4 T 28-03-2018 IPR018392 LysM domain A6A12_RS05340 5384d5f9c2b9a54e973b1ca855853e9e 824 SMART SM00091 132 198 5.9E-4 T 28-03-2018 IPR000014 PAS domain A6A12_RS05340 5384d5f9c2b9a54e973b1ca855853e9e 824 Gene3D G3DSA:3.20.20.450 416 669 5.6E-74 T 28-03-2018 IPR001633 EAL domain A6A12_RS05340 5384d5f9c2b9a54e973b1ca855853e9e 824 Pfam PF00571 CBS domain 770 821 3.6E-4 T 28-03-2018 IPR000644 CBS domain A6A12_RS05340 5384d5f9c2b9a54e973b1ca855853e9e 824 Gene3D G3DSA:3.40.50.10600 126 235 1.2E-13 T 28-03-2018 A6A12_RS05340 5384d5f9c2b9a54e973b1ca855853e9e 824 SUPERFAMILY SSF141868 424 669 5.49E-68 T 28-03-2018 IPR001633 EAL domain A6A12_RS05340 5384d5f9c2b9a54e973b1ca855853e9e 824 SUPERFAMILY SSF54631 703 822 3.92E-13 T 28-03-2018 A6A12_RS05340 5384d5f9c2b9a54e973b1ca855853e9e 824 SMART SM00052 419 666 1.0E-57 T 28-03-2018 IPR001633 EAL domain A6A12_RS05340 5384d5f9c2b9a54e973b1ca855853e9e 824 Pfam PF00989 PAS fold 134 238 2.6E-6 T 28-03-2018 IPR013767 PAS fold GO:0006355 A6A12_RS05340 5384d5f9c2b9a54e973b1ca855853e9e 824 Pfam PF00563 EAL domain 426 661 2.3E-58 T 28-03-2018 IPR001633 EAL domain A6A12_RS05340 5384d5f9c2b9a54e973b1ca855853e9e 824 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 129 242 1.6E-10 T 28-03-2018 IPR000014 PAS domain A6A12_RS05340 5384d5f9c2b9a54e973b1ca855853e9e 824 Gene3D G3DSA:3.10.580.10 701 824 8.4E-15 T 28-03-2018 A6A12_RS05340 5384d5f9c2b9a54e973b1ca855853e9e 824 SUPERFAMILY SSF55785 125 241 4.95E-16 T 28-03-2018 IPR000014 PAS domain A6A12_RS05340 5384d5f9c2b9a54e973b1ca855853e9e 824 Gene3D G3DSA:3.30.70.270 252 415 7.0E-8 T 28-03-2018 A6A12_RS02005 4623529978ea703b8b1eb2ce253356c0 358 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 14 356 5.3E-111 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A6A12_RS02005 4623529978ea703b8b1eb2ce253356c0 358 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 4 357 3.8E-177 T 28-03-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A6A12_RS02005 4623529978ea703b8b1eb2ce253356c0 358 SUPERFAMILY SSF51569 4 356 2.64E-129 T 28-03-2018 A6A12_RS02005 4623529978ea703b8b1eb2ce253356c0 358 Pfam PF01116 Fructose-bisphosphate aldolase class-II 17 354 6.8E-90 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A6A12_RS02005 4623529978ea703b8b1eb2ce253356c0 358 PIRSF PIRSF001359 13 358 1.3E-95 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A6A12_RS02005 4623529978ea703b8b1eb2ce253356c0 358 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 171 182 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A6A12_RS02005 4623529978ea703b8b1eb2ce253356c0 358 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 99 111 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 A6A12_RS02005 4623529978ea703b8b1eb2ce253356c0 358 Gene3D G3DSA:3.20.20.70 4 357 2.3E-100 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS04565 6bf1c7804c9da3ac86b2f4057a96176e 378 SUPERFAMILY SSF51338 1 53 5.98E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A6A12_RS04565 6bf1c7804c9da3ac86b2f4057a96176e 378 PIRSF PIRSF038994 1 378 2.7E-119 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A6A12_RS04565 6bf1c7804c9da3ac86b2f4057a96176e 378 Gene3D G3DSA:3.20.20.140 68 347 3.3E-95 T 28-03-2018 A6A12_RS04565 6bf1c7804c9da3ac86b2f4057a96176e 378 Gene3D G3DSA:2.30.40.10 2 67 1.5E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A6A12_RS04565 6bf1c7804c9da3ac86b2f4057a96176e 378 SUPERFAMILY SSF51556 54 347 4.87E-101 T 28-03-2018 IPR032466 Metal-dependent hydrolase A6A12_RS04565 6bf1c7804c9da3ac86b2f4057a96176e 378 Pfam PF01979 Amidohydrolase family 51 374 3.5E-36 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A6A12_RS04565 6bf1c7804c9da3ac86b2f4057a96176e 378 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 1 374 1.0E-153 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 A6A12_RS06670 1e526ffb3aad25df33c164bcde43374f 105 Pfam PF12321 Protein of unknown function (DUF3634) 2 103 6.9E-43 T 28-03-2018 IPR022090 Protein of unknown function DUF3634 A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 Gene3D G3DSA:1.10.560.10 1 185 3.5E-45 T 28-03-2018 IPR027413 GroEL-like equatorial domain A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 5.1E-252 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 Hamap MF_00600 60 kDa chaperonin [groL]. 2 543 41.283 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 SUPERFAMILY SSF52029 185 376 1.41E-82 T 28-03-2018 IPR027409 GroEL-like apical domain A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 SUPERFAMILY SSF54849 137 203 1.24E-24 T 28-03-2018 A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 PRINTS PR00298 60kDa chaperonin signature 350 375 2.5E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 PRINTS PR00298 60kDa chaperonin signature 27 53 2.5E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 PRINTS PR00298 60kDa chaperonin signature 83 110 2.5E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 PRINTS PR00298 60kDa chaperonin signature 398 419 2.5E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 PRINTS PR00298 60kDa chaperonin signature 268 291 2.5E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 SUPERFAMILY SSF48592 406 521 2.29E-77 T 28-03-2018 A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 SUPERFAMILY SSF48592 7 134 2.29E-77 T 28-03-2018 A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 Gene3D G3DSA:3.50.7.10 186 373 3.0E-97 T 28-03-2018 IPR027409 GroEL-like apical domain A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 522 2.2E-97 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A6A12_RS12835 3c3625111f29f9ee087d6d455d4e22bb 544 Gene3D G3DSA:1.10.560.10 374 516 4.1E-25 T 28-03-2018 IPR027413 GroEL-like equatorial domain A6A12_RS06995 a124dab0b9cf12468670dfe820ea64e5 210 PIRSF PIRSF006324 1 210 9.9E-55 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A6A12_RS06995 a124dab0b9cf12468670dfe820ea64e5 210 Pfam PF01810 LysE type translocator 15 208 4.2E-33 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A6A12_RS05045 fa07658a2f076eea2acff6ae37cf233f 220 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 115 215 5.0E-31 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 A6A12_RS05045 fa07658a2f076eea2acff6ae37cf233f 220 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 4 219 27.843 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 A6A12_RS05045 fa07658a2f076eea2acff6ae37cf233f 220 SUPERFAMILY SSF63848 113 218 3.01E-30 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 A6A12_RS05045 fa07658a2f076eea2acff6ae37cf233f 220 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 5 218 1.6E-75 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 A6A12_RS05045 fa07658a2f076eea2acff6ae37cf233f 220 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 1 102 6.9E-31 T 28-03-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 A6A12_RS05045 fa07658a2f076eea2acff6ae37cf233f 220 Gene3D G3DSA:2.160.20.70 96 220 2.6E-33 T 28-03-2018 A6A12_RS02920 cc96764d4cf9628233d6d736bcdd5804 98 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 86 5.3E-20 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A6A12_RS02920 cc96764d4cf9628233d6d736bcdd5804 98 Gene3D G3DSA:3.30.110.60 2 97 4.8E-25 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A6A12_RS02920 cc96764d4cf9628233d6d736bcdd5804 98 SUPERFAMILY SSF75471 1 93 9.55E-29 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A6A12_RS02920 cc96764d4cf9628233d6d736bcdd5804 98 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 98 2.0E-43 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A6A12_RS02920 cc96764d4cf9628233d6d736bcdd5804 98 SMART SM01103 3 86 8.8E-41 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A6A12_RS02920 cc96764d4cf9628233d6d736bcdd5804 98 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 3 97 4.6E-36 T 28-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 A6A12_RS02320 5264d1c5ff7bfb51a60342594bf9316a 111 Pfam PF01381 Helix-turn-helix 28 81 3.4E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A6A12_RS02320 5264d1c5ff7bfb51a60342594bf9316a 111 SUPERFAMILY SSF47413 17 80 5.63E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS02320 5264d1c5ff7bfb51a60342594bf9316a 111 SMART SM00530 27 82 5.9E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A6A12_RS02320 5264d1c5ff7bfb51a60342594bf9316a 111 Gene3D G3DSA:1.10.10.60 1 47 2.3E-7 T 28-03-2018 A6A12_RS02320 5264d1c5ff7bfb51a60342594bf9316a 111 Gene3D G3DSA:3.30.1190.10 48 107 1.4E-4 T 28-03-2018 A6A12_RS10850 220662d32f477458eec9aa2b12b229fc 262 Gene3D G3DSA:1.20.1180.10 197 262 6.4E-20 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 A6A12_RS10850 220662d32f477458eec9aa2b12b229fc 262 Gene3D G3DSA:2.160.10.10 1 196 4.2E-43 T 28-03-2018 A6A12_RS10850 220662d32f477458eec9aa2b12b229fc 262 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 5 262 42.123 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 A6A12_RS10850 220662d32f477458eec9aa2b12b229fc 262 PIRSF PIRSF000456 4 262 8.0E-95 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 A6A12_RS10850 220662d32f477458eec9aa2b12b229fc 262 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 8 260 1.3E-93 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 A6A12_RS10850 220662d32f477458eec9aa2b12b229fc 262 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 180 261 5.1E-25 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 A6A12_RS10850 220662d32f477458eec9aa2b12b229fc 262 SUPERFAMILY SSF51161 1 262 1.63E-73 T 28-03-2018 IPR011004 Trimeric LpxA-like A6A12_RS10850 220662d32f477458eec9aa2b12b229fc 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 2 33 1.0E-6 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS10850 220662d32f477458eec9aa2b12b229fc 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 36 69 2.5E-4 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS10850 220662d32f477458eec9aa2b12b229fc 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 143 3.9E-6 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS04200 a3554a96415b82656b04dad1806ab773 350 Gene3D G3DSA:1.10.287.470 103 147 2.5E-10 T 28-03-2018 A6A12_RS04200 a3554a96415b82656b04dad1806ab773 350 Gene3D G3DSA:2.40.50.100 148 309 1.0E-5 T 28-03-2018 A6A12_RS04200 a3554a96415b82656b04dad1806ab773 350 Gene3D G3DSA:3.90.1170.30 23 102 6.4E-6 T 28-03-2018 A6A12_RS04200 a3554a96415b82656b04dad1806ab773 350 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 32 337 1.2E-87 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A6A12_RS04200 a3554a96415b82656b04dad1806ab773 350 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 43 256 1.5E-31 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A6A12_RS04200 a3554a96415b82656b04dad1806ab773 350 SUPERFAMILY SSF111369 46 262 3.27E-39 T 28-03-2018 A6A12_RS05625 8ed4427988d7d418be9baa3725b4ee64 137 SUPERFAMILY SSF81273 2 58 1.84E-16 T 28-03-2018 A6A12_RS05625 8ed4427988d7d418be9baa3725b4ee64 137 Pfam PF00816 H-NS histone family 38 131 4.1E-18 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 A6A12_RS05625 8ed4427988d7d418be9baa3725b4ee64 137 SMART SM00528 90 137 8.8E-23 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 A6A12_RS05625 8ed4427988d7d418be9baa3725b4ee64 137 SUPERFAMILY SSF81273 95 137 6.28E-12 T 28-03-2018 A6A12_RS05625 8ed4427988d7d418be9baa3725b4ee64 137 Gene3D G3DSA:1.10.287.1050 1 57 3.1E-24 T 28-03-2018 IPR027454 Histone-like protein H-NS family, oligomerisation domain GO:0046983 A6A12_RS05625 8ed4427988d7d418be9baa3725b4ee64 137 Gene3D G3DSA:4.10.430.10 96 137 3.0E-19 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 A6A12_RS05625 8ed4427988d7d418be9baa3725b4ee64 137 PIRSF PIRSF002096 1 137 1.0E-52 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 A6A12_RS12355 6a361297426a1026ca239716d6b6c52f 461 Gene3D G3DSA:3.40.50.300 222 458 1.1E-41 T 28-03-2018 A6A12_RS12355 6a361297426a1026ca239716d6b6c52f 461 Pfam PF00270 DEAD/DEAH box helicase 28 194 1.8E-46 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A6A12_RS12355 6a361297426a1026ca239716d6b6c52f 461 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A6A12_RS12355 6a361297426a1026ca239716d6b6c52f 461 SMART SM00487 23 220 7.9E-57 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS12355 6a361297426a1026ca239716d6b6c52f 461 Pfam PF03880 DbpA RNA binding domain 388 458 1.6E-22 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain A6A12_RS12355 6a361297426a1026ca239716d6b6c52f 461 Pfam PF00271 Helicase conserved C-terminal domain 233 338 5.3E-27 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS12355 6a361297426a1026ca239716d6b6c52f 461 SUPERFAMILY SSF52540 73 358 1.84E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12355 6a361297426a1026ca239716d6b6c52f 461 Gene3D G3DSA:3.40.50.300 10 221 3.2E-59 T 28-03-2018 A6A12_RS12355 6a361297426a1026ca239716d6b6c52f 461 SMART SM00490 257 338 2.8E-28 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS01000 e15207f7005705770e60701996c43899 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 327 432 3.2E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS01000 e15207f7005705770e60701996c43899 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 390 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS01000 e15207f7005705770e60701996c43899 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 413 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS01000 e15207f7005705770e60701996c43899 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 376 1.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS01000 e15207f7005705770e60701996c43899 434 Gene3D G3DSA:3.30.565.10 287 434 2.5E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS01000 e15207f7005705770e60701996c43899 434 SUPERFAMILY SSF47384 220 281 3.92E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS01000 e15207f7005705770e60701996c43899 434 SMART SM00388 226 286 5.3E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS01000 e15207f7005705770e60701996c43899 434 SMART SM00387 325 434 5.2E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS01000 e15207f7005705770e60701996c43899 434 SUPERFAMILY SSF55874 288 433 2.62E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS01000 e15207f7005705770e60701996c43899 434 Gene3D G3DSA:1.10.287.130 216 282 1.6E-12 T 28-03-2018 A6A12_RS01000 e15207f7005705770e60701996c43899 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 227 280 2.0E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS01000 e15207f7005705770e60701996c43899 434 SMART SM00304 173 225 2.7E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS01000 e15207f7005705770e60701996c43899 434 Pfam PF00672 HAMP domain 173 221 4.1E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS08315 8e26829e6b0d574cbfbac612e5d54de7 344 Pfam PF09084 NMT1/THI5 like 61 267 2.6E-19 T 28-03-2018 IPR015168 SsuA/THI5-like A6A12_RS08315 8e26829e6b0d574cbfbac612e5d54de7 344 SUPERFAMILY SSF53850 47 267 1.12E-29 T 28-03-2018 A6A12_RS08315 8e26829e6b0d574cbfbac612e5d54de7 344 Gene3D G3DSA:3.40.190.10 144 335 9.3E-25 T 28-03-2018 A6A12_RS08315 8e26829e6b0d574cbfbac612e5d54de7 344 Gene3D G3DSA:3.40.190.10 44 133 1.7E-10 T 28-03-2018 A6A12_RS08185 16d1d0a1ed71a5d486a881cefac7d1d7 214 Pfam PF00072 Response regulator receiver domain 4 116 2.4E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS08185 16d1d0a1ed71a5d486a881cefac7d1d7 214 SUPERFAMILY SSF46894 135 210 8.16E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS08185 16d1d0a1ed71a5d486a881cefac7d1d7 214 Gene3D G3DSA:1.10.10.10 127 213 9.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS08185 16d1d0a1ed71a5d486a881cefac7d1d7 214 SUPERFAMILY SSF52172 3 132 9.11E-35 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS08185 16d1d0a1ed71a5d486a881cefac7d1d7 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 1.3E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS08185 16d1d0a1ed71a5d486a881cefac7d1d7 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 1.3E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS08185 16d1d0a1ed71a5d486a881cefac7d1d7 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 1.3E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS08185 16d1d0a1ed71a5d486a881cefac7d1d7 214 Gene3D G3DSA:3.40.50.2300 1 126 2.2E-36 T 28-03-2018 A6A12_RS08185 16d1d0a1ed71a5d486a881cefac7d1d7 214 SMART SM00421 146 203 1.1E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS08185 16d1d0a1ed71a5d486a881cefac7d1d7 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS08185 16d1d0a1ed71a5d486a881cefac7d1d7 214 SMART SM00448 2 115 2.9E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS08185 16d1d0a1ed71a5d486a881cefac7d1d7 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 3.4E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS07745 3cbe15a59b205900c808515bb4ef2946 212 SUPERFAMILY SSF56112 40 207 7.82E-21 T 28-03-2018 IPR011009 Protein kinase-like domain A6A12_RS07745 3cbe15a59b205900c808515bb4ef2946 212 Pfam PF00069 Protein kinase domain 43 182 1.1E-15 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A6A12_RS07745 3cbe15a59b205900c808515bb4ef2946 212 Gene3D G3DSA:1.10.510.10 39 190 1.6E-17 T 28-03-2018 A6A12_RS07745 3cbe15a59b205900c808515bb4ef2946 212 SMART SM00220 8 196 0.0015 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A6A12_RS02885 2de2b1efb944302693fec32cc7207578 430 SUPERFAMILY SSF51261 144 390 5.75E-72 T 28-03-2018 IPR011055 Duplicated hybrid motif A6A12_RS02885 2de2b1efb944302693fec32cc7207578 430 Pfam PF01551 Peptidase family M23 295 389 2.2E-31 T 28-03-2018 IPR016047 Peptidase M23 A6A12_RS02885 2de2b1efb944302693fec32cc7207578 430 Pfam PF04225 Opacity-associated protein A LysM-like domain 72 134 6.0E-5 T 28-03-2018 IPR007340 Opacity-associated protein A A6A12_RS02885 2de2b1efb944302693fec32cc7207578 430 Gene3D G3DSA:2.70.70.10 263 424 5.7E-40 T 28-03-2018 A6A12_RS02885 2de2b1efb944302693fec32cc7207578 430 Pfam PF08525 Opacity-associated protein A N-terminal motif 4 31 2.8E-5 T 28-03-2018 IPR013731 Opacity-associated protein A, N-terminal A6A12_RS05800 ae0bda132ee7db5ac306b9a5be7d7276 325 Pfam PF14397 Sugar-transfer associated ATP-grasp 24 296 4.3E-116 T 28-03-2018 A6A12_RS05800 ae0bda132ee7db5ac306b9a5be7d7276 325 TIGRFAM TIGR02291 rimK_rel_E_lig: alpha-L-glutamate ligase homolog 7 320 6.5E-168 T 28-03-2018 IPR011758 Alpha-L-glutamate ligase-related protein A6A12_RS05800 ae0bda132ee7db5ac306b9a5be7d7276 325 Gene3D G3DSA:3.30.1490.20 38 149 1.4E-6 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A6A12_RS05800 ae0bda132ee7db5ac306b9a5be7d7276 325 Gene3D G3DSA:3.30.470.20 150 288 1.6E-18 T 28-03-2018 A6A12_RS05800 ae0bda132ee7db5ac306b9a5be7d7276 325 SUPERFAMILY SSF56059 48 204 1.02E-19 T 28-03-2018 A6A12_RS05800 ae0bda132ee7db5ac306b9a5be7d7276 325 SUPERFAMILY SSF56059 234 282 1.02E-19 T 28-03-2018 A6A12_RS10540 cb6bdbb337ab572a9715cbe3acd3a092 314 SUPERFAMILY SSF53271 69 306 9.88E-67 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A6A12_RS10540 cb6bdbb337ab572a9715cbe3acd3a092 314 SMART SM01400 4 121 5.7E-78 T 28-03-2018 A6A12_RS10540 cb6bdbb337ab572a9715cbe3acd3a092 314 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 4 314 49.609 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A6A12_RS10540 cb6bdbb337ab572a9715cbe3acd3a092 314 Pfam PF14572 Phosphoribosyl synthetase-associated domain 204 313 1.7E-30 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A6A12_RS10540 cb6bdbb337ab572a9715cbe3acd3a092 314 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 129 144 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 A6A12_RS10540 cb6bdbb337ab572a9715cbe3acd3a092 314 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 4 314 6.3E-125 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A6A12_RS10540 cb6bdbb337ab572a9715cbe3acd3a092 314 Gene3D G3DSA:3.40.50.2020 1 155 7.7E-67 T 28-03-2018 A6A12_RS10540 cb6bdbb337ab572a9715cbe3acd3a092 314 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 4 121 1.4E-50 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A6A12_RS10540 cb6bdbb337ab572a9715cbe3acd3a092 314 Gene3D G3DSA:3.40.50.2020 156 290 5.7E-41 T 28-03-2018 A6A12_RS01885 4d5fe9a67dde08a4499e9c929d078baf 239 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 49 238 1.9E-67 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A6A12_RS01885 4d5fe9a67dde08a4499e9c929d078baf 239 Pfam PF02390 Putative methyltransferase 62 232 4.3E-59 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A6A12_RS01885 4d5fe9a67dde08a4499e9c929d078baf 239 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 23 238 30.102 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 A6A12_RS01885 4d5fe9a67dde08a4499e9c929d078baf 239 Gene3D G3DSA:3.40.50.150 29 239 8.2E-30 T 28-03-2018 A6A12_RS01885 4d5fe9a67dde08a4499e9c929d078baf 239 SUPERFAMILY SSF53335 15 236 1.72E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS04135 00221c44e23792286072208962a9c94d 225 Gene3D G3DSA:1.10.3720.10 13 225 1.0E-41 T 28-03-2018 A6A12_RS04135 00221c44e23792286072208962a9c94d 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 223 2.1E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS04135 00221c44e23792286072208962a9c94d 225 SUPERFAMILY SSF161098 15 212 5.1E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS14305 f1e85c5f1bdda35ed9c60af2aadbbe1b 175 Pfam PF12724 Flavodoxin domain 5 153 5.0E-49 T 28-03-2018 IPR026816 Flavodoxin domain A6A12_RS14305 f1e85c5f1bdda35ed9c60af2aadbbe1b 175 SUPERFAMILY SSF52218 3 158 6.55E-27 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS14305 f1e85c5f1bdda35ed9c60af2aadbbe1b 175 Gene3D G3DSA:3.40.50.360 1 173 3.2E-17 T 28-03-2018 IPR029039 Flavoprotein-like domain A6A12_RS09365 ef514dbca96cf9bab3ed4578113d6495 177 Gene3D G3DSA:3.40.50.300 4 171 6.3E-31 T 28-03-2018 A6A12_RS09365 ef514dbca96cf9bab3ed4578113d6495 177 SUPERFAMILY SSF52540 3 165 1.81E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09365 ef514dbca96cf9bab3ed4578113d6495 177 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 6 162 6.6E-66 T 28-03-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 A6A12_RS09365 ef514dbca96cf9bab3ed4578113d6495 177 Pfam PF01202 Shikimate kinase 13 162 8.9E-15 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A6A12_RS06250 ca4f1fdb5f51f0b23f49e5e22eb939a4 229 Pfam PF00072 Response regulator receiver domain 6 119 1.5E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS06250 ca4f1fdb5f51f0b23f49e5e22eb939a4 229 Gene3D G3DSA:1.10.10.10 173 227 1.8E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS06250 ca4f1fdb5f51f0b23f49e5e22eb939a4 229 SUPERFAMILY SSF52172 1 173 6.12E-31 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS06250 ca4f1fdb5f51f0b23f49e5e22eb939a4 229 PIRSF PIRSF006171 2 229 2.4E-73 T 28-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 A6A12_RS06250 ca4f1fdb5f51f0b23f49e5e22eb939a4 229 Pfam PF12431 Transcriptional regulator 135 163 4.5E-9 T 28-03-2018 IPR028141 Transcriptional regulator A6A12_RS06250 ca4f1fdb5f51f0b23f49e5e22eb939a4 229 SMART SM00448 4 119 6.6E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS06250 ca4f1fdb5f51f0b23f49e5e22eb939a4 229 Gene3D G3DSA:3.40.50.2300 1 172 6.2E-24 T 28-03-2018 A6A12_RS10110 fbea20585d8bd3712d0fe3a21a35f2c0 403 Gene3D G3DSA:3.40.47.10 4 257 4.7E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS10110 fbea20585d8bd3712d0fe3a21a35f2c0 403 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 358 3.5E-28 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal A6A12_RS10110 fbea20585d8bd3712d0fe3a21a35f2c0 403 Gene3D G3DSA:3.40.47.10 258 401 8.0E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS10110 fbea20585d8bd3712d0fe3a21a35f2c0 403 SUPERFAMILY SSF53901 213 401 4.03E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS10110 fbea20585d8bd3712d0fe3a21a35f2c0 403 SMART SM00825 Beta-ketoacyl synthase 4 403 1.4E-15 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain A6A12_RS10110 fbea20585d8bd3712d0fe3a21a35f2c0 403 SUPERFAMILY SSF53901 1 251 5.11E-68 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS10110 fbea20585d8bd3712d0fe3a21a35f2c0 403 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 244 2.1E-45 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A6A12_RS10110 fbea20585d8bd3712d0fe3a21a35f2c0 403 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 152 168 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site A6A12_RS05295 3b7ea61de89cb4e822802caa55af2719 240 Gene3D G3DSA:3.40.50.720 2 230 9.7E-42 T 28-03-2018 A6A12_RS05295 3b7ea61de89cb4e822802caa55af2719 240 Pfam PF00106 short chain dehydrogenase 2 182 1.2E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS05295 3b7ea61de89cb4e822802caa55af2719 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 2.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS05295 3b7ea61de89cb4e822802caa55af2719 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 2.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS05295 3b7ea61de89cb4e822802caa55af2719 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS05295 3b7ea61de89cb4e822802caa55af2719 240 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 128 156 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A6A12_RS05295 3b7ea61de89cb4e822802caa55af2719 240 SUPERFAMILY SSF51735 2 234 7.57E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS12015 2608925d376dff213ccccb9e71ddd6a1 502 SUPERFAMILY SSF52949 1 184 6.47E-52 T 28-03-2018 A6A12_RS12015 2608925d376dff213ccccb9e71ddd6a1 502 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 147 6.6E-34 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A6A12_RS12015 2608925d376dff213ccccb9e71ddd6a1 502 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 349 356 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A6A12_RS12015 2608925d376dff213ccccb9e71ddd6a1 502 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 187 489 3.2E-124 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A6A12_RS12015 2608925d376dff213ccccb9e71ddd6a1 502 PRINTS PR00481 Cytosol aminopeptidase signature 345 365 4.0E-55 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A6A12_RS12015 2608925d376dff213ccccb9e71ddd6a1 502 PRINTS PR00481 Cytosol aminopeptidase signature 323 344 4.0E-55 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A6A12_RS12015 2608925d376dff213ccccb9e71ddd6a1 502 PRINTS PR00481 Cytosol aminopeptidase signature 286 307 4.0E-55 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A6A12_RS12015 2608925d376dff213ccccb9e71ddd6a1 502 PRINTS PR00481 Cytosol aminopeptidase signature 264 281 4.0E-55 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A6A12_RS12015 2608925d376dff213ccccb9e71ddd6a1 502 PRINTS PR00481 Cytosol aminopeptidase signature 373 388 4.0E-55 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A6A12_RS12015 2608925d376dff213ccccb9e71ddd6a1 502 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 497 41.052 T 28-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 A6A12_RS12015 2608925d376dff213ccccb9e71ddd6a1 502 Gene3D G3DSA:3.40.220.10 1 166 2.1E-31 T 28-03-2018 A6A12_RS12015 2608925d376dff213ccccb9e71ddd6a1 502 Gene3D G3DSA:3.40.630.10 170 501 5.3E-136 T 28-03-2018 A6A12_RS12015 2608925d376dff213ccccb9e71ddd6a1 502 SUPERFAMILY SSF53187 179 496 1.72E-125 T 28-03-2018 A6A12_RS01820 6dfe5e4539e4a28f2b94724471455f70 284 Pfam PF05099 Tellurite resistance protein TerB 47 177 1.7E-18 T 28-03-2018 IPR007791 Co-chaperone DjlA, N-terminal A6A12_RS01820 6dfe5e4539e4a28f2b94724471455f70 284 SUPERFAMILY SSF46565 138 280 2.51E-34 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS01820 6dfe5e4539e4a28f2b94724471455f70 284 Gene3D G3DSA:1.10.287.110 184 282 2.7E-20 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS01820 6dfe5e4539e4a28f2b94724471455f70 284 Pfam PF00226 DnaJ domain 218 280 5.1E-15 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS01820 6dfe5e4539e4a28f2b94724471455f70 284 SMART SM00271 217 282 4.2E-23 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS01820 6dfe5e4539e4a28f2b94724471455f70 284 PRINTS PR00625 DnaJ domain signature 262 282 1.8E-12 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS01820 6dfe5e4539e4a28f2b94724471455f70 284 PRINTS PR00625 DnaJ domain signature 220 238 1.8E-12 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS01820 6dfe5e4539e4a28f2b94724471455f70 284 PRINTS PR00625 DnaJ domain signature 238 253 1.8E-12 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS01820 6dfe5e4539e4a28f2b94724471455f70 284 Gene3D G3DSA:1.10.3680.10 31 183 2.5E-32 T 28-03-2018 IPR029024 TerB-like A6A12_RS01820 6dfe5e4539e4a28f2b94724471455f70 284 SUPERFAMILY SSF158682 48 181 8.63E-24 T 28-03-2018 A6A12_RS01820 6dfe5e4539e4a28f2b94724471455f70 284 Hamap MF_01153 Co-chaperone protein DjlA [djlA]. 3 283 39.602 T 28-03-2018 IPR023749 Co-chaperone DjlA GO:0051087 A6A12_RS01105 716acb8ff4fc7f1c0ff932e141d2f987 446 SUPERFAMILY SSF56024 9 187 3.66E-27 T 28-03-2018 A6A12_RS01105 716acb8ff4fc7f1c0ff932e141d2f987 446 SMART SM00155 347 374 0.0081 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A6A12_RS01105 716acb8ff4fc7f1c0ff932e141d2f987 446 SMART SM00155 126 152 0.0012 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A6A12_RS01105 716acb8ff4fc7f1c0ff932e141d2f987 446 Gene3D G3DSA:3.30.870.10 11 233 2.6E-18 T 28-03-2018 A6A12_RS01105 716acb8ff4fc7f1c0ff932e141d2f987 446 Pfam PF13091 PLD-like domain 251 402 1.7E-25 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A6A12_RS01105 716acb8ff4fc7f1c0ff932e141d2f987 446 Gene3D G3DSA:3.30.870.10 241 413 4.4E-23 T 28-03-2018 A6A12_RS01105 716acb8ff4fc7f1c0ff932e141d2f987 446 PIRSF PIRSF000850 1 446 1.7E-222 T 28-03-2018 A6A12_RS01105 716acb8ff4fc7f1c0ff932e141d2f987 446 SUPERFAMILY SSF56024 248 422 9.16E-26 T 28-03-2018 A6A12_RS04120 7174d519f1578ef9c2523e8de8cf554f 185 Hamap MF_01104 Protein Syd [syd]. 7 185 36.481 T 28-03-2018 IPR009948 Syd GO:0009898 A6A12_RS04120 7174d519f1578ef9c2523e8de8cf554f 185 Pfam PF07348 Syd protein (SUKH-2) 11 183 1.9E-69 T 28-03-2018 IPR009948 Syd GO:0009898 A6A12_RS13740 645adbe1271cc527867adf7b15459bb0 300 Pfam PF13580 SIS domain 39 167 6.8E-9 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A6A12_RS13740 645adbe1271cc527867adf7b15459bb0 300 SUPERFAMILY SSF53697 7 251 6.67E-68 T 28-03-2018 A6A12_RS13740 645adbe1271cc527867adf7b15459bb0 300 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 4 297 42.814 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 A6A12_RS13740 645adbe1271cc527867adf7b15459bb0 300 Gene3D G3DSA:1.10.8.10 245 270 1.7E-11 T 28-03-2018 A6A12_RS13740 645adbe1271cc527867adf7b15459bb0 300 Gene3D G3DSA:1.10.8.10 271 297 2.9E-6 T 28-03-2018 A6A12_RS13740 645adbe1271cc527867adf7b15459bb0 300 Gene3D G3DSA:3.40.50.10490 12 244 4.0E-49 T 28-03-2018 A6A12_RS13740 645adbe1271cc527867adf7b15459bb0 300 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 187 204 - T 28-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 A6A12_RS13740 645adbe1271cc527867adf7b15459bb0 300 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 8 297 7.6E-131 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 A6A12_RS03475 a8ebf565fd63a6bc8e1740e6e26c2d3a 618 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 348 597 1.8E-82 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial A6A12_RS03475 a8ebf565fd63a6bc8e1740e6e26c2d3a 618 PRINTS PR00702 Acriflavin resistance protein family signature 581 604 3.6E-5 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS03475 a8ebf565fd63a6bc8e1740e6e26c2d3a 618 PRINTS PR00702 Acriflavin resistance protein family signature 452 475 3.6E-5 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS03475 a8ebf565fd63a6bc8e1740e6e26c2d3a 618 PRINTS PR00702 Acriflavin resistance protein family signature 506 530 3.6E-5 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS03475 a8ebf565fd63a6bc8e1740e6e26c2d3a 618 Pfam PF07549 SecD/SecF GG Motif 115 141 3.6E-7 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site A6A12_RS03475 a8ebf565fd63a6bc8e1740e6e26c2d3a 618 Pfam PF13721 SecD export protein N-terminal TM region 2 103 5.6E-37 T 28-03-2018 IPR027398 SecD export protein N-terminal TM domain A6A12_RS03475 a8ebf565fd63a6bc8e1740e6e26c2d3a 618 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 123 604 1.4E-150 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A6A12_RS03475 a8ebf565fd63a6bc8e1740e6e26c2d3a 618 Gene3D G3DSA:1.20.1640.10 392 609 2.4E-29 T 28-03-2018 A6A12_RS03475 a8ebf565fd63a6bc8e1740e6e26c2d3a 618 SUPERFAMILY SSF82866 413 609 1.44E-44 T 28-03-2018 A6A12_RS03475 a8ebf565fd63a6bc8e1740e6e26c2d3a 618 Pfam PF02355 Protein export membrane protein 436 597 2.2E-18 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A6A12_RS03475 a8ebf565fd63a6bc8e1740e6e26c2d3a 618 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 3 618 49.743 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 A6A12_RS04955 db1346240a52268338bf52aa4e5a9671 331 Gene3D G3DSA:3.40.50.720 1 159 1.4E-78 T 28-03-2018 A6A12_RS04955 db1346240a52268338bf52aa4e5a9671 331 Gene3D G3DSA:3.30.360.10 160 314 8.7E-76 T 28-03-2018 A6A12_RS04955 db1346240a52268338bf52aa4e5a9671 331 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 155 312 2.2E-67 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS04955 db1346240a52268338bf52aa4e5a9671 331 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 148 155 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS04955 db1346240a52268338bf52aa4e5a9671 331 PIRSF PIRSF000149 1 331 4.6E-132 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS04955 db1346240a52268338bf52aa4e5a9671 331 SUPERFAMILY SSF51735 3 166 2.72E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS04955 db1346240a52268338bf52aa4e5a9671 331 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 3.2E-40 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS04955 db1346240a52268338bf52aa4e5a9671 331 SUPERFAMILY SSF55347 149 312 6.55E-75 T 28-03-2018 A6A12_RS04955 db1346240a52268338bf52aa4e5a9671 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 1.0E-44 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS04955 db1346240a52268338bf52aa4e5a9671 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 144 162 1.0E-44 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS04955 db1346240a52268338bf52aa4e5a9671 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 171 187 1.0E-44 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS04955 db1346240a52268338bf52aa4e5a9671 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 1.0E-44 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS04955 db1346240a52268338bf52aa4e5a9671 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 1.0E-44 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS04955 db1346240a52268338bf52aa4e5a9671 331 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 1.5E-134 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS04955 db1346240a52268338bf52aa4e5a9671 331 SMART SM00846 3 150 1.5E-94 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS14415 7fa9317c43a5919841169ac4543f6583 453 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 10 453 1.2E-101 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 A6A12_RS14415 7fa9317c43a5919841169ac4543f6583 453 Pfam PF12631 MnmE helical domain 122 450 5.4E-62 T 28-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 A6A12_RS14415 7fa9317c43a5919841169ac4543f6583 453 Pfam PF01926 50S ribosome-binding GTPase 217 306 1.1E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS14415 7fa9317c43a5919841169ac4543f6583 453 Gene3D G3DSA:3.30.1360.120 1 120 5.6E-41 T 28-03-2018 A6A12_RS14415 7fa9317c43a5919841169ac4543f6583 453 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 453 32.925 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 A6A12_RS14415 7fa9317c43a5919841169ac4543f6583 453 Gene3D G3DSA:1.20.120.430 121 280 9.6E-28 T 28-03-2018 A6A12_RS14415 7fa9317c43a5919841169ac4543f6583 453 SUPERFAMILY SSF52540 187 371 3.45E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS14415 7fa9317c43a5919841169ac4543f6583 453 SUPERFAMILY SSF52540 70 151 3.45E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS14415 7fa9317c43a5919841169ac4543f6583 453 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 119 1.0E-35 T 28-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 A6A12_RS14415 7fa9317c43a5919841169ac4543f6583 453 Gene3D G3DSA:1.20.120.430 281 453 1.3E-32 T 28-03-2018 A6A12_RS14415 7fa9317c43a5919841169ac4543f6583 453 SUPERFAMILY SSF116878 120 219 8.89E-53 T 28-03-2018 A6A12_RS14415 7fa9317c43a5919841169ac4543f6583 453 SUPERFAMILY SSF116878 378 453 8.89E-53 T 28-03-2018 A6A12_RS14415 7fa9317c43a5919841169ac4543f6583 453 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 215 368 5.3E-23 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A6A12_RS04130 d19f745e3e2f0af1bb189662ba5d020a 269 Gene3D G3DSA:3.40.190.10 32 147 1.1E-40 T 28-03-2018 A6A12_RS04130 d19f745e3e2f0af1bb189662ba5d020a 269 PIRSF PIRSF002854 1 269 1.9E-97 T 28-03-2018 IPR004872 Lipoprotein NlpA family A6A12_RS04130 d19f745e3e2f0af1bb189662ba5d020a 269 Gene3D G3DSA:3.40.190.10 148 269 6.5E-38 T 28-03-2018 A6A12_RS04130 d19f745e3e2f0af1bb189662ba5d020a 269 SUPERFAMILY SSF53850 32 269 2.46E-78 T 28-03-2018 A6A12_RS04130 d19f745e3e2f0af1bb189662ba5d020a 269 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 15 269 1.4E-125 T 28-03-2018 IPR004872 Lipoprotein NlpA family A6A12_RS04130 d19f745e3e2f0af1bb189662ba5d020a 269 Pfam PF03180 NLPA lipoprotein 33 269 4.2E-97 T 28-03-2018 IPR004872 Lipoprotein NlpA family A6A12_RS00300 96418fbe54772ea7e1cfc887320c411e 185 SUPERFAMILY SSF55821 3 181 2.26E-56 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain A6A12_RS00300 96418fbe54772ea7e1cfc887320c411e 185 Pfam PF01300 Telomere recombination 9 185 6.3E-49 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 A6A12_RS00300 96418fbe54772ea7e1cfc887320c411e 185 Gene3D G3DSA:3.90.870.10 2 185 4.1E-54 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain A6A12_RS00300 96418fbe54772ea7e1cfc887320c411e 185 Hamap MF_01852 Threonylcarbamoyl-AMP synthase [tsaC]. 1 183 40.988 T 28-03-2018 IPR023535 Threonylcarbamoyl-AMP synthase GO:0002949|GO:0005524 A6A12_RS00300 96418fbe54772ea7e1cfc887320c411e 185 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 5 185 8.1E-37 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 A6A12_RS00385 244a94c619449f04a7360c80dac3a270 72 Pfam PF13627 Prokaryotic lipoprotein-attachment site 40 61 1.9E-9 T 28-03-2018 IPR032831 Prokaryotic lipoprotein-attachment site A6A12_RS12990 4c13107dcd090eed2b238d6861f07668 484 SUPERFAMILY SSF48557 15 468 7.81E-141 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 A6A12_RS12990 4c13107dcd090eed2b238d6861f07668 484 Pfam PF00206 Lyase 24 356 1.8E-99 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal A6A12_RS12990 4c13107dcd090eed2b238d6861f07668 484 Gene3D G3DSA:1.10.275.10 14 152 1.6E-51 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal A6A12_RS12990 4c13107dcd090eed2b238d6861f07668 484 ProSitePatterns PS00163 Fumarate lyases signature. 331 340 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A6A12_RS12990 4c13107dcd090eed2b238d6861f07668 484 Gene3D G3DSA:1.20.200.10 153 429 3.2E-71 T 28-03-2018 A6A12_RS12990 4c13107dcd090eed2b238d6861f07668 484 PRINTS PR00149 Fumarate lyase superfamily signature 149 167 1.6E-25 T 28-03-2018 IPR000362 Fumarate lyase family A6A12_RS12990 4c13107dcd090eed2b238d6861f07668 484 PRINTS PR00149 Fumarate lyase superfamily signature 194 212 1.6E-25 T 28-03-2018 IPR000362 Fumarate lyase family A6A12_RS12990 4c13107dcd090eed2b238d6861f07668 484 PRINTS PR00149 Fumarate lyase superfamily signature 285 312 1.6E-25 T 28-03-2018 IPR000362 Fumarate lyase family A6A12_RS12990 4c13107dcd090eed2b238d6861f07668 484 PRINTS PR00149 Fumarate lyase superfamily signature 331 347 1.6E-25 T 28-03-2018 IPR000362 Fumarate lyase family A6A12_RS12990 4c13107dcd090eed2b238d6861f07668 484 Pfam PF10415 Fumarase C C-terminus 422 474 1.8E-17 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A6A12_RS12990 4c13107dcd090eed2b238d6861f07668 484 Gene3D G3DSA:1.10.40.30 430 479 6.1E-19 T 28-03-2018 A6A12_RS12990 4c13107dcd090eed2b238d6861f07668 484 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 17 483 9.0E-252 T 28-03-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 A6A12_RS02275 36340f069c4b11e7a7fe20b213c35bd1 591 SUPERFAMILY SSF116734 95 286 2.45E-34 T 28-03-2018 A6A12_RS02275 36340f069c4b11e7a7fe20b213c35bd1 591 SUPERFAMILY SSF116734 332 356 2.45E-34 T 28-03-2018 A6A12_RS02275 36340f069c4b11e7a7fe20b213c35bd1 591 SUPERFAMILY SSF116734 385 574 4.58E-29 T 28-03-2018 A6A12_RS02275 36340f069c4b11e7a7fe20b213c35bd1 591 Gene3D G3DSA:3.90.220.20 73 270 1.7E-32 T 28-03-2018 A6A12_RS02275 36340f069c4b11e7a7fe20b213c35bd1 591 Gene3D G3DSA:3.90.220.20 385 551 1.3E-20 T 28-03-2018 A6A12_RS02275 36340f069c4b11e7a7fe20b213c35bd1 591 Pfam PF01420 Type I restriction modification DNA specificity domain 397 563 2.1E-7 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A6A12_RS02275 36340f069c4b11e7a7fe20b213c35bd1 591 Pfam PF01420 Type I restriction modification DNA specificity domain 101 288 1.0E-12 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A6A12_RS02275 36340f069c4b11e7a7fe20b213c35bd1 591 Gene3D G3DSA:1.10.287.1120 271 384 4.4E-16 T 28-03-2018 A6A12_RS07955 015872c80420bfcabe581a5373abd558 313 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 302 1.6E-163 T 28-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 A6A12_RS07955 015872c80420bfcabe581a5373abd558 313 PIRSF PIRSF000450 1 309 5.1E-148 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 A6A12_RS07955 015872c80420bfcabe581a5373abd558 313 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 2.0E-127 T 28-03-2018 A6A12_RS07955 015872c80420bfcabe581a5373abd558 313 Pfam PF04204 Homoserine O-succinyltransferase 2 299 2.6E-135 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 A6A12_RS07955 015872c80420bfcabe581a5373abd558 313 Hamap MF_00295 Homoserine O-succinyltransferase [metA]. 1 301 53.341 T 28-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 A6A12_RS07955 015872c80420bfcabe581a5373abd558 313 SUPERFAMILY SSF52317 18 297 3.4E-102 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS07955 015872c80420bfcabe581a5373abd558 313 Gene3D G3DSA:3.40.50.880 34 301 1.8E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS08730 9f3734908f030ceba932b735469e9199 65 Gene3D G3DSA:1.10.10.10 4 63 9.0E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS08730 9f3734908f030ceba932b735469e9199 65 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 2 51 6.9E-23 T 28-03-2018 IPR010260 DNA-binding transcriptional activator AlpA A6A12_RS02045 7de831a6ccd13a1cf0e8e118f21f44e5 610 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 610 40.379 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A6A12_RS02045 7de831a6ccd13a1cf0e8e118f21f44e5 610 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 610 4.8E-261 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A6A12_RS02045 7de831a6ccd13a1cf0e8e118f21f44e5 610 Gene3D G3DSA:3.60.20.10 2 239 1.7E-68 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A6A12_RS02045 7de831a6ccd13a1cf0e8e118f21f44e5 610 SUPERFAMILY SSF56235 2 233 7.21E-75 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A6A12_RS02045 7de831a6ccd13a1cf0e8e118f21f44e5 610 Pfam PF01380 SIS domain 290 419 6.1E-32 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A6A12_RS02045 7de831a6ccd13a1cf0e8e118f21f44e5 610 Pfam PF01380 SIS domain 463 592 8.2E-26 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A6A12_RS02045 7de831a6ccd13a1cf0e8e118f21f44e5 610 Gene3D G3DSA:3.40.50.10490 240 458 6.0E-61 T 28-03-2018 A6A12_RS02045 7de831a6ccd13a1cf0e8e118f21f44e5 610 Pfam PF13522 Glutamine amidotransferase domain 62 174 7.7E-21 T 28-03-2018 A6A12_RS02045 7de831a6ccd13a1cf0e8e118f21f44e5 610 SUPERFAMILY SSF53697 245 610 2.32E-113 T 28-03-2018 A6A12_RS02045 7de831a6ccd13a1cf0e8e118f21f44e5 610 Gene3D G3DSA:3.40.50.10490 459 608 2.9E-49 T 28-03-2018 A6A12_RS02375 93cbb0f5d6940d9f15986f1b1baafc33 267 Pfam PF02673 Bacitracin resistance protein BacA 6 257 1.0E-81 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A6A12_RS02375 93cbb0f5d6940d9f15986f1b1baafc33 267 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 257 8.1E-74 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A6A12_RS02375 93cbb0f5d6940d9f15986f1b1baafc33 267 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 264 17.261 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A6A12_RS04615 242711746d6ebe57e2e4787b5325b6e2 441 PRINTS PR00173 Glutamate-aspartate symporter signature 20 40 1.5E-6 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS04615 242711746d6ebe57e2e4787b5325b6e2 441 PRINTS PR00173 Glutamate-aspartate symporter signature 374 393 1.5E-6 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS04615 242711746d6ebe57e2e4787b5325b6e2 441 Pfam PF13726 Na+-H+ antiporter family 2 88 4.1E-35 T 28-03-2018 IPR032813 Putative Na+/H+ antiporter, N-terminal A6A12_RS04615 242711746d6ebe57e2e4787b5325b6e2 441 Pfam PF03553 Na+/H+ antiporter family 150 435 5.4E-74 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A6A12_RS03365 8c9cb552ce29fe7d4152cb1bc0ac202f 240 PIRSF PIRSF005426 1 240 7.9E-83 T 28-03-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 A6A12_RS03365 8c9cb552ce29fe7d4152cb1bc0ac202f 240 Gene3D G3DSA:3.40.109.10 1 240 6.6E-61 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A6A12_RS03365 8c9cb552ce29fe7d4152cb1bc0ac202f 240 SUPERFAMILY SSF55469 1 238 3.14E-71 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A6A12_RS03365 8c9cb552ce29fe7d4152cb1bc0ac202f 240 Pfam PF00881 Nitroreductase family 8 159 1.1E-21 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A6A12_RS08790 f34c8d299968f35d1d9d0575da9d1534 445 SUPERFAMILY SSF69304 170 443 1.2E-57 T 28-03-2018 A6A12_RS08790 f34c8d299968f35d1d9d0575da9d1534 445 Pfam PF04052 TolB amino-terminal domain 19 121 8.7E-36 T 28-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 A6A12_RS08790 f34c8d299968f35d1d9d0575da9d1534 445 SUPERFAMILY SSF52964 24 176 1.31E-40 T 28-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 A6A12_RS08790 f34c8d299968f35d1d9d0575da9d1534 445 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 12 442 3.5E-169 T 28-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 A6A12_RS08790 f34c8d299968f35d1d9d0575da9d1534 445 Gene3D G3DSA:3.40.50.10070 18 179 4.8E-41 T 28-03-2018 A6A12_RS08790 f34c8d299968f35d1d9d0575da9d1534 445 Hamap MF_00671 Protein TolB [tolB]. 5 441 35.597 T 28-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 A6A12_RS08790 f34c8d299968f35d1d9d0575da9d1534 445 Gene3D G3DSA:2.130.10.150 274 444 1.5E-31 T 28-03-2018 A6A12_RS08790 f34c8d299968f35d1d9d0575da9d1534 445 Pfam PF07676 WD40-like Beta Propeller Repeat 252 287 1.5E-7 T 28-03-2018 IPR011659 WD40-like Beta Propeller A6A12_RS08790 f34c8d299968f35d1d9d0575da9d1534 445 Pfam PF07676 WD40-like Beta Propeller Repeat 217 243 3.2E-8 T 28-03-2018 IPR011659 WD40-like Beta Propeller A6A12_RS08790 f34c8d299968f35d1d9d0575da9d1534 445 Pfam PF07676 WD40-like Beta Propeller Repeat 295 331 7.5E-15 T 28-03-2018 IPR011659 WD40-like Beta Propeller A6A12_RS08790 f34c8d299968f35d1d9d0575da9d1534 445 Gene3D G3DSA:2.130.10.10 213 273 6.5E-10 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A6A12_RS00405 b0d26dfb378162e5ed687eabffbefbfb 310 Gene3D G3DSA:1.10.443.10 121 297 3.2E-43 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS00405 b0d26dfb378162e5ed687eabffbefbfb 310 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 16 99 1.4E-20 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A6A12_RS00405 b0d26dfb378162e5ed687eabffbefbfb 310 Gene3D G3DSA:1.10.150.130 10 120 9.9E-20 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A6A12_RS00405 b0d26dfb378162e5ed687eabffbefbfb 310 SUPERFAMILY SSF56349 16 297 5.89E-53 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS00405 b0d26dfb378162e5ed687eabffbefbfb 310 Pfam PF00589 Phage integrase family 121 289 1.5E-49 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS00405 b0d26dfb378162e5ed687eabffbefbfb 310 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 18 305 1.8E-108 T 28-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 A6A12_RS00405 b0d26dfb378162e5ed687eabffbefbfb 310 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 14 303 55.011 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD A6A12_RS08025 6fb0ef086e19fba1b25c43449df9a449 189 Gene3D G3DSA:3.40.50.300 2 181 4.7E-59 T 28-03-2018 A6A12_RS08025 6fb0ef086e19fba1b25c43449df9a449 189 SUPERFAMILY SSF52540 2 181 4.43E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS08025 6fb0ef086e19fba1b25c43449df9a449 189 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 4 179 1.6E-56 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A6A12_RS08025 6fb0ef086e19fba1b25c43449df9a449 189 PIRSF PIRSF006135 1 182 1.2E-51 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A6A12_RS12270 1ec72b7bfd18771a78fe043690c94b9e 240 Pfam PF10986 Protein of unknown function (DUF2796) 153 236 2.5E-18 T 28-03-2018 IPR021253 Protein of unknown function DUF2796 A6A12_RS12270 1ec72b7bfd18771a78fe043690c94b9e 240 Pfam PF10986 Protein of unknown function (DUF2796) 48 162 5.8E-30 T 28-03-2018 IPR021253 Protein of unknown function DUF2796 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 Gene3D G3DSA:3.30.70.1430 40 141 1.9E-28 T 28-03-2018 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 SUPERFAMILY SSF82714 704 788 9.55E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 SUPERFAMILY SSF82866 794 1008 1.11E-48 T 28-03-2018 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 Gene3D G3DSA:3.30.2090.10 181 266 1.2E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 Gene3D G3DSA:3.30.70.1430 556 655 2.3E-8 T 28-03-2018 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 Pfam PF00873 AcrB/AcrD/AcrF family 4 1008 1.1E-280 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 SUPERFAMILY SSF82693 554 657 2.93E-15 T 28-03-2018 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 Gene3D G3DSA:1.20.1640.10 267 491 1.1E-42 T 28-03-2018 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 Gene3D G3DSA:1.20.1640.10 790 1010 6.4E-44 T 28-03-2018 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 Gene3D G3DSA:3.30.2090.10 703 789 4.1E-20 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 SUPERFAMILY SSF82866 290 489 1.05E-45 T 28-03-2018 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.0E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.0E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.0E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.0E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.0E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 PRINTS PR00702 Acriflavin resistance protein family signature 611 625 1.0E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.0E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.0E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 PRINTS PR00702 Acriflavin resistance protein family signature 541 558 1.0E-72 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 SUPERFAMILY SSF82693 139 181 2.2E-18 T 28-03-2018 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 SUPERFAMILY SSF82693 268 324 2.2E-18 T 28-03-2018 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 SUPERFAMILY SSF82693 40 134 3.14E-25 T 28-03-2018 A6A12_RS04205 43893254414a878647a08b24070c4e11 1036 SUPERFAMILY SSF82714 183 266 3.01E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains A6A12_RS05570 559e5189d7d53c2c6d618d4c19738c90 197 PIRSF PIRSF028788 10 197 1.7E-37 T 28-03-2018 IPR026256 Transcriptional regulator, TfoX/Sxy-type A6A12_RS05570 559e5189d7d53c2c6d618d4c19738c90 197 SUPERFAMILY SSF159894 3 103 6.02E-24 T 28-03-2018 A6A12_RS05570 559e5189d7d53c2c6d618d4c19738c90 197 Pfam PF04993 TfoX N-terminal domain 13 100 3.2E-22 T 28-03-2018 IPR007076 TfoX, N-terminal A6A12_RS05570 559e5189d7d53c2c6d618d4c19738c90 197 Gene3D G3DSA:3.30.1460.30 5 103 4.5E-13 T 28-03-2018 A6A12_RS05570 559e5189d7d53c2c6d618d4c19738c90 197 Pfam PF04994 TfoX C-terminal domain 114 192 3.4E-27 T 28-03-2018 IPR007077 TfoX, C-terminal A6A12_RS05570 559e5189d7d53c2c6d618d4c19738c90 197 Gene3D G3DSA:1.10.150.20 115 194 9.3E-19 T 28-03-2018 A6A12_RS10770 18caa3d10cb293ebd52db3326d2e3df3 814 SUPERFAMILY SSF56645 122 356 2.75E-42 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 A6A12_RS10770 18caa3d10cb293ebd52db3326d2e3df3 814 SUPERFAMILY SSF47203 361 508 4.67E-23 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A6A12_RS10770 18caa3d10cb293ebd52db3326d2e3df3 814 Gene3D G3DSA:2.40.110.10 237 359 1.4E-15 T 28-03-2018 A6A12_RS10770 18caa3d10cb293ebd52db3326d2e3df3 814 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 148 234 2.9E-16 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A6A12_RS10770 18caa3d10cb293ebd52db3326d2e3df3 814 Gene3D G3DSA:1.20.140.10 361 509 4.3E-20 T 28-03-2018 A6A12_RS10770 18caa3d10cb293ebd52db3326d2e3df3 814 Pfam PF09317 Domain of unknown function (DUF1974) 515 796 3.6E-112 T 28-03-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 A6A12_RS10770 18caa3d10cb293ebd52db3326d2e3df3 814 Gene3D G3DSA:1.10.540.10 77 236 6.4E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 A6A12_RS10770 18caa3d10cb293ebd52db3326d2e3df3 814 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 361 508 1.4E-13 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 A6A12_RS10085 55bea7eed1e8550a55d093135b0f6b7b 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 7.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS10085 55bea7eed1e8550a55d093135b0f6b7b 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 7.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS10085 55bea7eed1e8550a55d093135b0f6b7b 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 7.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS10085 55bea7eed1e8550a55d093135b0f6b7b 300 SUPERFAMILY SSF53850 96 295 2.72E-39 T 28-03-2018 A6A12_RS10085 55bea7eed1e8550a55d093135b0f6b7b 300 Gene3D G3DSA:3.40.190.10 95 184 1.0E-16 T 28-03-2018 A6A12_RS10085 55bea7eed1e8550a55d093135b0f6b7b 300 Gene3D G3DSA:1.10.10.10 2 89 8.9E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS10085 55bea7eed1e8550a55d093135b0f6b7b 300 Pfam PF03466 LysR substrate binding domain 94 294 4.4E-43 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS10085 55bea7eed1e8550a55d093135b0f6b7b 300 Gene3D G3DSA:3.40.190.10 185 268 7.1E-21 T 28-03-2018 A6A12_RS10085 55bea7eed1e8550a55d093135b0f6b7b 300 SUPERFAMILY SSF46785 7 92 2.59E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS10085 55bea7eed1e8550a55d093135b0f6b7b 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 3.3E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS00315 c6faebc979ad2bf9c5c9b073dfae1794 88 Pfam PF07369 Protein of unknown function (DUF1488) 5 85 5.5E-24 T 28-03-2018 IPR009962 Protein of unknown function DUF1488 A6A12_RS00315 c6faebc979ad2bf9c5c9b073dfae1794 88 Gene3D G3DSA:3.30.160.140 5 85 3.6E-26 T 28-03-2018 IPR009962 Protein of unknown function DUF1488 A6A12_RS00315 c6faebc979ad2bf9c5c9b073dfae1794 88 SUPERFAMILY SSF160272 1 86 5.36E-28 T 28-03-2018 IPR009962 Protein of unknown function DUF1488 A6A12_RS07160 0b5dba5299156332ca5bcf0f511559c8 303 SUPERFAMILY SSF53850 91 297 1.99E-37 T 28-03-2018 A6A12_RS07160 0b5dba5299156332ca5bcf0f511559c8 303 Gene3D G3DSA:1.10.10.10 2 91 1.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS07160 0b5dba5299156332ca5bcf0f511559c8 303 Gene3D G3DSA:3.40.190.10 181 264 4.2E-16 T 28-03-2018 A6A12_RS07160 0b5dba5299156332ca5bcf0f511559c8 303 Pfam PF03466 LysR substrate binding domain 91 292 9.0E-38 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS07160 0b5dba5299156332ca5bcf0f511559c8 303 Gene3D G3DSA:3.40.190.10 97 180 5.9E-11 T 28-03-2018 A6A12_RS07160 0b5dba5299156332ca5bcf0f511559c8 303 SUPERFAMILY SSF46785 3 112 1.03E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS07160 0b5dba5299156332ca5bcf0f511559c8 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 7.4E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS07440 d3f5a66e00e79d4693b1027388a895a5 484 SUPERFAMILY SSF109604 270 469 5.65E-32 T 28-03-2018 A6A12_RS07440 d3f5a66e00e79d4693b1027388a895a5 484 Pfam PF13487 HD domain 353 422 7.3E-18 T 28-03-2018 A6A12_RS07440 d3f5a66e00e79d4693b1027388a895a5 484 Gene3D G3DSA:1.10.3210.10 118 481 5.1E-46 T 28-03-2018 A6A12_RS07440 d3f5a66e00e79d4693b1027388a895a5 484 SMART SM00471 290 440 1.2E-8 T 28-03-2018 IPR003607 HD/PDEase domain A6A12_RS00685 587ee1eef535c760d8e5e3c09165d82a 115 Gene3D G3DSA:1.10.10.10 39 111 4.6E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS00375 1c7fecb8f91370747e15ed680c238592 842 Pfam PF01295 Adenylate cyclase, class-I 226 828 6.3E-255 T 28-03-2018 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 A6A12_RS00375 1c7fecb8f91370747e15ed680c238592 842 PIRSF PIRSF001444 1 842 0.0 T 28-03-2018 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 A6A12_RS00375 1c7fecb8f91370747e15ed680c238592 842 Pfam PF12633 Adenylate cyclase NT domain 5 198 8.0E-77 T 28-03-2018 IPR024685 Adenylate cyclase class-I, N-terminal domain KEGG: 00230+4.6.1.1 A6A12_RS09970 b8c8c35139b0b51d135181ec65d33680 75 SUPERFAMILY SSF50037 4 74 2.13E-17 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal A6A12_RS09970 b8c8c35139b0b51d135181ec65d33680 75 SMART SM00899 1 74 3.4E-20 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A6A12_RS09970 b8c8c35139b0b51d135181ec65d33680 75 Gene3D G3DSA:2.30.30.90 4 75 1.5E-17 T 28-03-2018 A6A12_RS09970 b8c8c35139b0b51d135181ec65d33680 75 Pfam PF04023 FeoA domain 1 74 6.3E-15 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A6A12_RS08780 1d18015e7ac090b67423414f138ebcfc 258 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 141 257 6.6E-37 T 28-03-2018 IPR014162 Cell division coordinator CpoB, C-terminal A6A12_RS08780 1d18015e7ac090b67423414f138ebcfc 258 Gene3D G3DSA:1.25.40.10 211 258 1.3E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS08780 1d18015e7ac090b67423414f138ebcfc 258 Pfam PF13174 Tetratricopeptide repeat 215 247 3.4E-6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS08780 1d18015e7ac090b67423414f138ebcfc 258 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 5 258 17.151 T 28-03-2018 IPR034706 Cell division coordinator CpoB GO:0051301 A6A12_RS08780 1d18015e7ac090b67423414f138ebcfc 258 SMART SM00028 214 247 12.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS08780 1d18015e7ac090b67423414f138ebcfc 258 SMART SM00028 178 211 26.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS08780 1d18015e7ac090b67423414f138ebcfc 258 Pfam PF13432 Tetratricopeptide repeat 152 205 7.9E-7 T 28-03-2018 A6A12_RS08780 1d18015e7ac090b67423414f138ebcfc 258 SUPERFAMILY SSF48452 140 254 2.4E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS08780 1d18015e7ac090b67423414f138ebcfc 258 Gene3D G3DSA:1.25.40.10 160 210 1.3E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS08780 1d18015e7ac090b67423414f138ebcfc 258 Pfam PF16331 TolA binding protein trimerisation 47 120 4.3E-23 T 28-03-2018 IPR032519 YbgF, trimerisation domain GO:0070206 A6A12_RS08780 1d18015e7ac090b67423414f138ebcfc 258 Gene3D G3DSA:1.25.40.10 54 159 0.38 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS00735 a1f41f53567c004673a5bb71ed2dbc7e 609 Gene3D G3DSA:2.170.130.10 19 157 2.1E-36 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 A6A12_RS00735 a1f41f53567c004673a5bb71ed2dbc7e 609 Pfam PF00593 TonB dependent receptor 210 607 3.6E-37 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A6A12_RS00735 a1f41f53567c004673a5bb71ed2dbc7e 609 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 35 - T 28-03-2018 IPR010916 TonB box, conserved site A6A12_RS00735 a1f41f53567c004673a5bb71ed2dbc7e 609 Pfam PF07715 TonB-dependent Receptor Plug Domain 43 146 3.8E-30 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 A6A12_RS00735 a1f41f53567c004673a5bb71ed2dbc7e 609 SUPERFAMILY SSF56935 29 609 1.47E-105 T 28-03-2018 A6A12_RS00735 a1f41f53567c004673a5bb71ed2dbc7e 609 Gene3D G3DSA:2.40.170.20 160 609 1.9E-55 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A6A12_RS00735 a1f41f53567c004673a5bb71ed2dbc7e 609 Hamap MF_01531 Vitamin B12 transporter BtuB [btuB]. 1 609 34.141 T 28-03-2018 IPR010101 TonB-dependent vitamin B12 transporter BtuB GO:0004872|GO:0015235|GO:0015889|GO:0016020 A6A12_RS04835 58410bf0828ff06dfa22fbf1b9f9f667 201 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 29 201 2.1E-69 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 A6A12_RS04835 58410bf0828ff06dfa22fbf1b9f9f667 201 PIRSF PIRSF015617 6 201 1.3E-66 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 A6A12_RS04835 58410bf0828ff06dfa22fbf1b9f9f667 201 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 32 201 2.4E-59 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 A6A12_RS04835 58410bf0828ff06dfa22fbf1b9f9f667 201 Gene3D G3DSA:3.40.50.300 11 201 1.7E-69 T 28-03-2018 A6A12_RS04835 58410bf0828ff06dfa22fbf1b9f9f667 201 Pfam PF12557 Cob(I)alamin adenosyltransferase N terminal 3 26 5.4E-8 T 28-03-2018 IPR025826 Cob(I)alamin adenosyltransferase N-terminal domain KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 A6A12_RS04835 58410bf0828ff06dfa22fbf1b9f9f667 201 SUPERFAMILY SSF52540 12 201 2.77E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12105 73bd5ef29a846ec19a01e0230d559965 102 Pfam PF13466 STAS domain 16 93 1.0E-17 T 28-03-2018 IPR002645 STAS domain A6A12_RS12105 73bd5ef29a846ec19a01e0230d559965 102 SUPERFAMILY SSF52091 4 96 2.75E-17 T 28-03-2018 IPR002645 STAS domain A6A12_RS12105 73bd5ef29a846ec19a01e0230d559965 102 Gene3D G3DSA:3.30.750.24 5 101 1.3E-9 T 28-03-2018 IPR002645 STAS domain A6A12_RS02395 efb1f9b15d595f7756e9cc886d78ad02 365 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 24 360 28.539 T 28-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS02395 efb1f9b15d595f7756e9cc886d78ad02 365 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 27 189 1.2E-41 T 28-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS02395 efb1f9b15d595f7756e9cc886d78ad02 365 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 202 355 6.5E-22 T 28-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS02395 efb1f9b15d595f7756e9cc886d78ad02 365 SUPERFAMILY SSF55120 24 356 3.74E-97 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS02395 efb1f9b15d595f7756e9cc886d78ad02 365 Gene3D G3DSA:3.30.2340.10 188 321 9.8E-26 T 28-03-2018 A6A12_RS02395 efb1f9b15d595f7756e9cc886d78ad02 365 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 96 109 - T 28-03-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 A6A12_RS02395 efb1f9b15d595f7756e9cc886d78ad02 365 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 30 260 5.7E-55 T 28-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS12225 8432ae56bb9f40d977e5c87eb4b7de78 336 Gene3D G3DSA:3.40.190.80 199 333 4.1E-57 T 28-03-2018 A6A12_RS12225 8432ae56bb9f40d977e5c87eb4b7de78 336 PIRSF PIRSF000904 1 336 2.1E-124 T 28-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A6A12_RS12225 8432ae56bb9f40d977e5c87eb4b7de78 336 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 5 333 42.454 T 28-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A6A12_RS12225 8432ae56bb9f40d977e5c87eb4b7de78 336 SUPERFAMILY SSF56655 3 331 2.11E-113 T 28-03-2018 A6A12_RS12225 8432ae56bb9f40d977e5c87eb4b7de78 336 PIRSF PIRSF500210 1 336 2.0E-127 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A6A12_RS12225 8432ae56bb9f40d977e5c87eb4b7de78 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 67 93 6.9E-73 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A6A12_RS12225 8432ae56bb9f40d977e5c87eb4b7de78 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 208 235 6.9E-73 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A6A12_RS12225 8432ae56bb9f40d977e5c87eb4b7de78 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 182 205 6.9E-73 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A6A12_RS12225 8432ae56bb9f40d977e5c87eb4b7de78 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 307 332 6.9E-73 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A6A12_RS12225 8432ae56bb9f40d977e5c87eb4b7de78 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 30 57 6.9E-73 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A6A12_RS12225 8432ae56bb9f40d977e5c87eb4b7de78 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 151 174 6.9E-73 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A6A12_RS12225 8432ae56bb9f40d977e5c87eb4b7de78 336 Gene3D G3DSA:3.30.540.10 4 198 1.2E-64 T 28-03-2018 A6A12_RS12225 8432ae56bb9f40d977e5c87eb4b7de78 336 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 6 196 3.6E-77 T 28-03-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A6A12_RS12225 8432ae56bb9f40d977e5c87eb4b7de78 336 ProSitePatterns PS00124 Fructose-1-6-bisphosphatase active site. 273 285 - T 28-03-2018 IPR020548 Fructose-1,6-bisphosphatase, active site GO:0005975|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 A6A12_RS06685 49aa7342ec221a7e3781a637d18a21d2 111 Gene3D G3DSA:1.10.10.60 4 36 0.0027 T 28-03-2018 A6A12_RS06685 49aa7342ec221a7e3781a637d18a21d2 111 Gene3D G3DSA:1.10.10.10 44 104 2.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05470 cf2a88e92b14a7792c443b8e099c7043 265 Pfam PF13531 Bacterial extracellular solute-binding protein 38 263 5.0E-26 T 28-03-2018 A6A12_RS05470 cf2a88e92b14a7792c443b8e099c7043 265 Gene3D G3DSA:3.40.190.10 38 129 5.2E-12 T 28-03-2018 A6A12_RS05470 cf2a88e92b14a7792c443b8e099c7043 265 Gene3D G3DSA:3.40.190.10 130 265 2.2E-8 T 28-03-2018 A6A12_RS05470 cf2a88e92b14a7792c443b8e099c7043 265 SUPERFAMILY SSF53850 35 263 2.02E-29 T 28-03-2018 A6A12_RS07135 e76c68ba49899a6ab4208f5cf98fa8b4 328 TIGRFAM TIGR04380 myo_inos_iolG: inositol 2-dehydrogenase 1 326 1.3E-136 T 28-03-2018 IPR030827 Inositol 2-dehydrogenase A6A12_RS07135 e76c68ba49899a6ab4208f5cf98fa8b4 328 Gene3D G3DSA:3.30.360.10 131 328 2.8E-44 T 28-03-2018 A6A12_RS07135 e76c68ba49899a6ab4208f5cf98fa8b4 328 SUPERFAMILY SSF51735 2 142 2.88E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS07135 e76c68ba49899a6ab4208f5cf98fa8b4 328 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 119 2.5E-21 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 A6A12_RS07135 e76c68ba49899a6ab4208f5cf98fa8b4 328 SUPERFAMILY SSF55347 124 287 7.46E-37 T 28-03-2018 A6A12_RS07135 e76c68ba49899a6ab4208f5cf98fa8b4 328 Gene3D G3DSA:3.40.50.720 1 130 3.5E-35 T 28-03-2018 A6A12_RS07135 e76c68ba49899a6ab4208f5cf98fa8b4 328 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 132 238 4.2E-8 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 A6A12_RS01765 da0cf5d8fe006f932076377a3ebebca8 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 82 4.4E-43 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01765 da0cf5d8fe006f932076377a3ebebca8 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 3.6E-39 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01765 da0cf5d8fe006f932076377a3ebebca8 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 3.6E-39 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01765 da0cf5d8fe006f932076377a3ebebca8 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 3.6E-39 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01765 da0cf5d8fe006f932076377a3ebebca8 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 29.422 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01765 da0cf5d8fe006f932076377a3ebebca8 85 SUPERFAMILY SSF110324 2 80 1.46E-34 T 28-03-2018 A6A12_RS01765 da0cf5d8fe006f932076377a3ebebca8 85 Pfam PF01016 Ribosomal L27 protein 2 82 1.2E-39 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01765 da0cf5d8fe006f932076377a3ebebca8 85 Gene3D G3DSA:2.40.50.100 20 84 4.2E-31 T 28-03-2018 A6A12_RS01765 da0cf5d8fe006f932076377a3ebebca8 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS01765 da0cf5d8fe006f932076377a3ebebca8 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 6.0E-18 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS10905 3d871fc6c499da0a6fa9d2ffadcadc5f 281 Gene3D G3DSA:3.30.479.20 110 146 0.0016 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS10905 3d871fc6c499da0a6fa9d2ffadcadc5f 281 Gene3D G3DSA:3.30.479.20 58 109 4.4E-8 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS10905 3d871fc6c499da0a6fa9d2ffadcadc5f 281 Pfam PF00889 Elongation factor TS 71 261 4.5E-61 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS10905 3d871fc6c499da0a6fa9d2ffadcadc5f 281 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS10905 3d871fc6c499da0a6fa9d2ffadcadc5f 281 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS10905 3d871fc6c499da0a6fa9d2ffadcadc5f 281 Gene3D G3DSA:1.10.8.10 1 56 4.1E-22 T 28-03-2018 A6A12_RS10905 3d871fc6c499da0a6fa9d2ffadcadc5f 281 Gene3D G3DSA:3.30.479.20 147 278 8.1E-44 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS10905 3d871fc6c499da0a6fa9d2ffadcadc5f 281 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 280 2.2E-102 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS10905 3d871fc6c499da0a6fa9d2ffadcadc5f 281 SUPERFAMILY SSF46934 4 54 1.63E-17 T 28-03-2018 IPR009060 UBA-like GO:0005515 A6A12_RS10905 3d871fc6c499da0a6fa9d2ffadcadc5f 281 SUPERFAMILY SSF54713 142 279 3.92E-47 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS10905 3d871fc6c499da0a6fa9d2ffadcadc5f 281 Hamap MF_00050 Elongation factor Ts [tsf]. 1 280 76.333 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS10905 3d871fc6c499da0a6fa9d2ffadcadc5f 281 SUPERFAMILY SSF54713 56 138 1.22E-17 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 A6A12_RS07645 45126af99c053fd35819dc128da9ea22 287 Gene3D G3DSA:3.20.20.150 4 276 4.7E-71 T 28-03-2018 A6A12_RS07645 45126af99c053fd35819dc128da9ea22 287 SUPERFAMILY SSF51658 30 209 6.39E-12 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A6A12_RS07645 45126af99c053fd35819dc128da9ea22 287 Pfam PF05114 Protein of unknown function (DUF692) 10 268 2.3E-91 T 28-03-2018 IPR007801 Uncharacterised protein family UPF0276 A6A12_RS02785 9daaac616ef19a59caa9bb9fa616a560 337 PIRSF PIRSF002825 3 337 1.1E-97 T 28-03-2018 IPR026045 Ferric binding protein A6A12_RS02785 9daaac616ef19a59caa9bb9fa616a560 337 SUPERFAMILY SSF53850 24 332 2.78E-72 T 28-03-2018 A6A12_RS02785 9daaac616ef19a59caa9bb9fa616a560 337 Pfam PF13343 Bacterial extracellular solute-binding protein 73 295 1.6E-18 T 28-03-2018 A6A12_RS02785 9daaac616ef19a59caa9bb9fa616a560 337 Gene3D G3DSA:3.40.190.10 153 294 3.0E-23 T 28-03-2018 A6A12_RS02785 9daaac616ef19a59caa9bb9fa616a560 337 Gene3D G3DSA:3.40.190.10 22 152 4.5E-18 T 28-03-2018 A6A12_RS12720 75894a22c936c69c38934895e3c85044 242 Pfam PF08534 Redoxin 5 160 7.1E-34 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 A6A12_RS12720 75894a22c936c69c38934895e3c85044 242 Gene3D G3DSA:3.40.30.10 3 159 3.8E-29 T 28-03-2018 A6A12_RS12720 75894a22c936c69c38934895e3c85044 242 TIGRFAM TIGR02190 GlrX-dom: glutaredoxin-family domain 164 242 2.4E-41 T 28-03-2018 IPR011906 Glutaredoxin domain KEGG: 00480+1.11.1.15 A6A12_RS12720 75894a22c936c69c38934895e3c85044 242 SUPERFAMILY SSF52833 4 241 4.7E-49 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS12720 75894a22c936c69c38934895e3c85044 242 ProSitePatterns PS00195 Glutaredoxin active site. 175 191 - T 28-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 A6A12_RS12720 75894a22c936c69c38934895e3c85044 242 Gene3D G3DSA:3.40.30.10 160 241 1.9E-22 T 28-03-2018 A6A12_RS12720 75894a22c936c69c38934895e3c85044 242 Pfam PF00462 Glutaredoxin 173 231 8.7E-20 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A6A12_RS12720 75894a22c936c69c38934895e3c85044 242 PRINTS PR00160 Glutaredoxin signature 228 241 1.5E-15 T 28-03-2018 IPR014025 Glutaredoxin subgroup A6A12_RS12720 75894a22c936c69c38934895e3c85044 242 PRINTS PR00160 Glutaredoxin signature 173 191 1.5E-15 T 28-03-2018 IPR014025 Glutaredoxin subgroup A6A12_RS12720 75894a22c936c69c38934895e3c85044 242 PRINTS PR00160 Glutaredoxin signature 214 227 1.5E-15 T 28-03-2018 IPR014025 Glutaredoxin subgroup A6A12_RS03500 883e62c501ec8055696bf2b97dee7fb8 404 Gene3D G3DSA:3.40.640.10 1 232 6.3E-53 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS03500 883e62c501ec8055696bf2b97dee7fb8 404 PIRSF PIRSF005572 2 384 2.6E-138 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 A6A12_RS03500 883e62c501ec8055696bf2b97dee7fb8 404 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 197 216 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A6A12_RS03500 883e62c501ec8055696bf2b97dee7fb8 404 Gene3D G3DSA:3.90.1150.10 233 404 5.1E-55 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS03500 883e62c501ec8055696bf2b97dee7fb8 404 Pfam PF00266 Aminotransferase class-V 5 368 1.2E-90 T 28-03-2018 IPR000192 Aminotransferase class V domain A6A12_RS03500 883e62c501ec8055696bf2b97dee7fb8 404 SUPERFAMILY SSF53383 5 391 2.55E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS03500 883e62c501ec8055696bf2b97dee7fb8 404 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 1 395 54.049 T 28-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 A6A12_RS03500 883e62c501ec8055696bf2b97dee7fb8 404 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 1 404 3.0E-229 T 28-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 A6A12_RS05990 92857d11bac5e85afc9c17c20167c83e 212 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 89 4.7E-8 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A6A12_RS05990 92857d11bac5e85afc9c17c20167c83e 212 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 89 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A6A12_RS11920 a57806f156c57a7164fe481689cec3b7 319 SUPERFAMILY SSF46785 22 99 3.89E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS11920 a57806f156c57a7164fe481689cec3b7 319 Pfam PF03466 LysR substrate binding domain 124 308 1.2E-20 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS11920 a57806f156c57a7164fe481689cec3b7 319 SUPERFAMILY SSF53850 106 309 7.24E-38 T 28-03-2018 A6A12_RS11920 a57806f156c57a7164fe481689cec3b7 319 Gene3D G3DSA:3.40.190.10 201 282 9.8E-11 T 28-03-2018 A6A12_RS11920 a57806f156c57a7164fe481689cec3b7 319 Gene3D G3DSA:1.10.10.10 19 101 1.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS11920 a57806f156c57a7164fe481689cec3b7 319 Gene3D G3DSA:3.40.190.10 112 200 9.9E-11 T 28-03-2018 A6A12_RS11920 a57806f156c57a7164fe481689cec3b7 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 25 84 1.3E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS11920 a57806f156c57a7164fe481689cec3b7 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 61 1.4E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS11920 a57806f156c57a7164fe481689cec3b7 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 61 72 1.4E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS11920 a57806f156c57a7164fe481689cec3b7 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.4E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS05685 49b9c40613d08e3ea1cd753e2a7f75db 73 SUPERFAMILY SSF50249 1 67 2.36E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS05685 49b9c40613d08e3ea1cd753e2a7f75db 73 PIRSF PIRSF002599 1 73 3.2E-23 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 A6A12_RS05685 49b9c40613d08e3ea1cd753e2a7f75db 73 PRINTS PR00050 Cold shock protein signature 4 19 4.0E-15 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A6A12_RS05685 49b9c40613d08e3ea1cd753e2a7f75db 73 PRINTS PR00050 Cold shock protein signature 25 34 4.0E-15 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A6A12_RS05685 49b9c40613d08e3ea1cd753e2a7f75db 73 PRINTS PR00050 Cold shock protein signature 40 58 4.0E-15 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A6A12_RS05685 49b9c40613d08e3ea1cd753e2a7f75db 73 TIGRFAM TIGR02381 cspD: cold shock domain protein CspD 1 68 4.3E-42 T 28-03-2018 IPR012751 CspD, cold shock GO:0003676|GO:0005737|GO:0006355|GO:0006950 A6A12_RS05685 49b9c40613d08e3ea1cd753e2a7f75db 73 SMART SM00357 3 67 2.6E-27 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 A6A12_RS05685 49b9c40613d08e3ea1cd753e2a7f75db 73 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site A6A12_RS05685 49b9c40613d08e3ea1cd753e2a7f75db 73 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.9E-28 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A6A12_RS05685 49b9c40613d08e3ea1cd753e2a7f75db 73 Gene3D G3DSA:2.40.50.140 1 73 1.5E-25 T 28-03-2018 A6A12_RS05035 778e124212bbe26ab2c9999c4926abaf 88 Pfam PF03776 Septum formation topological specificity factor MinE 15 84 1.8E-23 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 A6A12_RS05035 778e124212bbe26ab2c9999c4926abaf 88 Gene3D G3DSA:3.30.1070.10 1 85 1.7E-27 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 A6A12_RS05035 778e124212bbe26ab2c9999c4926abaf 88 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 85 1.1E-32 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 A6A12_RS05035 778e124212bbe26ab2c9999c4926abaf 88 SUPERFAMILY SSF55229 34 87 7.06E-17 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 A6A12_RS05035 778e124212bbe26ab2c9999c4926abaf 88 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 86 19.141 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 A6A12_RS03000 d66671a1b4b357e35306e326d94fe207 136 Pfam PF12802 MarR family 29 88 7.9E-11 T 28-03-2018 A6A12_RS03000 d66671a1b4b357e35306e326d94fe207 136 SUPERFAMILY SSF46785 10 134 3.97E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03000 d66671a1b4b357e35306e326d94fe207 136 Gene3D G3DSA:1.10.10.10 1 134 1.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03000 d66671a1b4b357e35306e326d94fe207 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 2.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A6A12_RS03000 d66671a1b4b357e35306e326d94fe207 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 2.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A6A12_RS03000 d66671a1b4b357e35306e326d94fe207 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 2.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A6A12_RS03000 d66671a1b4b357e35306e326d94fe207 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 2.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A6A12_RS03000 d66671a1b4b357e35306e326d94fe207 136 SMART SM00347 23 124 6.0E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A6A12_RS12540 9f9ecbec53b0e3609d47de3fca7d850c 313 SUPERFAMILY SSF56235 5 309 6.08E-98 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A6A12_RS12540 9f9ecbec53b0e3609d47de3fca7d850c 313 Gene3D G3DSA:3.60.20.30 178 313 3.2E-48 T 28-03-2018 A6A12_RS12540 9f9ecbec53b0e3609d47de3fca7d850c 313 Pfam PF01112 Asparaginase 6 307 1.1E-110 T 28-03-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 A6A12_RS06085 77f88d93f1c161846cc3c919f23875b5 231 SMART SM00363 1 59 1.0E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS06085 77f88d93f1c161846cc3c919f23875b5 231 SUPERFAMILY SSF55174 1 80 7.51E-14 T 28-03-2018 A6A12_RS06085 77f88d93f1c161846cc3c919f23875b5 231 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 98 112 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A6A12_RS06085 77f88d93f1c161846cc3c919f23875b5 231 Pfam PF01479 S4 domain 1 42 9.8E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS06085 77f88d93f1c161846cc3c919f23875b5 231 SUPERFAMILY SSF55120 60 226 5.12E-46 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS06085 77f88d93f1c161846cc3c919f23875b5 231 Gene3D G3DSA:3.30.2350.10 69 231 1.4E-33 T 28-03-2018 A6A12_RS06085 77f88d93f1c161846cc3c919f23875b5 231 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 65 223 1.1E-47 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A6A12_RS06085 77f88d93f1c161846cc3c919f23875b5 231 Gene3D G3DSA:3.10.290.10 1 68 6.2E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS06085 77f88d93f1c161846cc3c919f23875b5 231 Pfam PF00849 RNA pseudouridylate synthase 61 191 8.3E-17 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS01525 2391a21ca17b5b2a699b7be5d310f44f 373 Pfam PF00266 Aminotransferase class-V 13 350 3.2E-39 T 28-03-2018 IPR000192 Aminotransferase class V domain A6A12_RS01525 2391a21ca17b5b2a699b7be5d310f44f 373 PIRSF PIRSF000524 5 373 8.6E-112 T 28-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 A6A12_RS01525 2391a21ca17b5b2a699b7be5d310f44f 373 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 189 209 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A6A12_RS01525 2391a21ca17b5b2a699b7be5d310f44f 373 Gene3D G3DSA:3.40.640.10 20 264 7.0E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS01525 2391a21ca17b5b2a699b7be5d310f44f 373 Gene3D G3DSA:3.90.1150.10 265 373 1.3E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS01525 2391a21ca17b5b2a699b7be5d310f44f 373 SUPERFAMILY SSF53383 9 371 3.13E-101 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS03845 be19f3e11eb7ea494994c4d576859c9d 512 Gene3D G3DSA:3.40.50.150 144 467 1.7E-53 T 28-03-2018 A6A12_RS03845 be19f3e11eb7ea494994c4d576859c9d 512 SUPERFAMILY SSF53335 6 509 3.4E-119 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS03845 be19f3e11eb7ea494994c4d576859c9d 512 Pfam PF12161 HsdM N-terminal domain 6 113 1.9E-11 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain A6A12_RS03845 be19f3e11eb7ea494994c4d576859c9d 512 Pfam PF02384 N-6 DNA Methylase 123 442 4.0E-67 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A6A12_RS03845 be19f3e11eb7ea494994c4d576859c9d 512 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 320 344 4.9E-22 T 28-03-2018 A6A12_RS03845 be19f3e11eb7ea494994c4d576859c9d 512 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 170 184 4.9E-22 T 28-03-2018 A6A12_RS03845 be19f3e11eb7ea494994c4d576859c9d 512 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 146 162 4.9E-22 T 28-03-2018 A6A12_RS03845 be19f3e11eb7ea494994c4d576859c9d 512 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 278 290 4.9E-22 T 28-03-2018 A6A12_RS03845 be19f3e11eb7ea494994c4d576859c9d 512 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 281 287 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A6A12_RS13130 76bc676e7b9236d89c1dbf9427502ca3 530 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 7 530 45.685 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A6A12_RS13130 76bc676e7b9236d89c1dbf9427502ca3 530 PIRSF PIRSF000414 1 530 4.1E-227 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A6A12_RS13130 76bc676e7b9236d89c1dbf9427502ca3 530 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 9 530 1.2E-259 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A6A12_RS13130 76bc676e7b9236d89c1dbf9427502ca3 530 SUPERFAMILY SSF52335 7 197 4.06E-71 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A6A12_RS13130 76bc676e7b9236d89c1dbf9427502ca3 530 SMART SM00851 19 132 8.8E-61 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A6A12_RS13130 76bc676e7b9236d89c1dbf9427502ca3 530 Pfam PF01808 AICARFT/IMPCHase bienzyme 137 461 1.7E-118 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A6A12_RS13130 76bc676e7b9236d89c1dbf9427502ca3 530 Gene3D G3DSA:3.40.50.1380 1 196 1.0E-77 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A6A12_RS13130 76bc676e7b9236d89c1dbf9427502ca3 530 Gene3D G3DSA:3.40.140.20 376 520 1.1E-53 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A6A12_RS13130 76bc676e7b9236d89c1dbf9427502ca3 530 Gene3D G3DSA:3.40.140.20 227 375 6.5E-55 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A6A12_RS13130 76bc676e7b9236d89c1dbf9427502ca3 530 Pfam PF02142 MGS-like domain 19 132 1.9E-30 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain A6A12_RS13130 76bc676e7b9236d89c1dbf9427502ca3 530 SMART SM00798 137 462 6.9E-215 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A6A12_RS13130 76bc676e7b9236d89c1dbf9427502ca3 530 SUPERFAMILY SSF53927 222 530 5.11E-130 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A6A12_RS13715 cbf3d8302b3f727120b3b1bd061785f8 308 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 62 80 3.7E-7 T 28-03-2018 IPR008091 Ferrichrome-binding periplasmic protein A6A12_RS13715 cbf3d8302b3f727120b3b1bd061785f8 308 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 93 108 3.7E-7 T 28-03-2018 IPR008091 Ferrichrome-binding periplasmic protein A6A12_RS13715 cbf3d8302b3f727120b3b1bd061785f8 308 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 282 295 3.7E-7 T 28-03-2018 IPR008091 Ferrichrome-binding periplasmic protein A6A12_RS13715 cbf3d8302b3f727120b3b1bd061785f8 308 Gene3D G3DSA:3.40.50.1980 146 305 4.6E-22 T 28-03-2018 A6A12_RS13715 cbf3d8302b3f727120b3b1bd061785f8 308 Pfam PF01497 Periplasmic binding protein 45 228 7.8E-19 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A6A12_RS13715 cbf3d8302b3f727120b3b1bd061785f8 308 SUPERFAMILY SSF53807 40 301 6.28E-51 T 28-03-2018 A6A12_RS13715 cbf3d8302b3f727120b3b1bd061785f8 308 Gene3D G3DSA:3.40.50.1980 25 145 5.4E-28 T 28-03-2018 A6A12_RS11565 bfc974bd16b98f66bf5527031459ec9e 316 PIRSF PIRSF004486 1 316 4.9E-101 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS11565 bfc974bd16b98f66bf5527031459ec9e 316 SUPERFAMILY SSF53335 7 113 1.41E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS11565 bfc974bd16b98f66bf5527031459ec9e 316 SUPERFAMILY SSF53335 217 316 1.41E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS11565 bfc974bd16b98f66bf5527031459ec9e 316 Pfam PF01795 MraW methylase family 5 315 5.0E-110 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS11565 bfc974bd16b98f66bf5527031459ec9e 316 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 315 5.0E-119 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS11565 bfc974bd16b98f66bf5527031459ec9e 316 Gene3D G3DSA:1.10.150.170 122 219 3.4E-34 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS11565 bfc974bd16b98f66bf5527031459ec9e 316 SUPERFAMILY SSF81799 113 216 5.49E-31 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS11565 bfc974bd16b98f66bf5527031459ec9e 316 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 316 38.209 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 A6A12_RS11565 bfc974bd16b98f66bf5527031459ec9e 316 Gene3D G3DSA:3.40.50.150 7 121 9.2E-15 T 28-03-2018 A6A12_RS11550 1b6b07ba3a1aa5098725bd3492a8d1d1 495 Gene3D G3DSA:3.40.1390.10 4 100 1.9E-18 T 28-03-2018 A6A12_RS11550 1b6b07ba3a1aa5098725bd3492a8d1d1 495 Gene3D G3DSA:3.90.190.20 344 495 2.9E-47 T 28-03-2018 A6A12_RS11550 1b6b07ba3a1aa5098725bd3492a8d1d1 495 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 26 491 3.0E-170 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A6A12_RS11550 1b6b07ba3a1aa5098725bd3492a8d1d1 495 Pfam PF02875 Mur ligase family, glutamate ligase domain 341 423 2.0E-22 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A6A12_RS11550 1b6b07ba3a1aa5098725bd3492a8d1d1 495 Gene3D G3DSA:3.40.1190.10 101 337 1.4E-51 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS11550 1b6b07ba3a1aa5098725bd3492a8d1d1 495 SUPERFAMILY SSF53623 112 338 3.14E-73 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS11550 1b6b07ba3a1aa5098725bd3492a8d1d1 495 SUPERFAMILY SSF63418 5 107 1.7E-21 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A6A12_RS11550 1b6b07ba3a1aa5098725bd3492a8d1d1 495 SUPERFAMILY SSF53244 340 491 2.49E-48 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A6A12_RS11550 1b6b07ba3a1aa5098725bd3492a8d1d1 495 Pfam PF01225 Mur ligase family, catalytic domain 27 105 7.4E-10 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 A6A12_RS11550 1b6b07ba3a1aa5098725bd3492a8d1d1 495 Pfam PF08245 Mur ligase middle domain 117 318 4.3E-51 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS11550 1b6b07ba3a1aa5098725bd3492a8d1d1 495 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 5 491 33.324 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 A6A12_RS12515 8cbb2835ba0217c858705c64c319c5ee 246 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 243 1.9E-86 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 A6A12_RS12515 8cbb2835ba0217c858705c64c319c5ee 246 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 3 244 43.439 T 28-03-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB A6A12_RS12515 8cbb2835ba0217c858705c64c319c5ee 246 Gene3D G3DSA:3.40.1280.10 77 246 6.4E-50 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A6A12_RS12515 8cbb2835ba0217c858705c64c319c5ee 246 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 6 79 2.2E-18 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A6A12_RS12515 8cbb2835ba0217c858705c64c319c5ee 246 SUPERFAMILY SSF55315 3 77 8.0E-19 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like A6A12_RS12515 8cbb2835ba0217c858705c64c319c5ee 246 Pfam PF00588 SpoU rRNA Methylase family 97 237 1.9E-39 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A6A12_RS12515 8cbb2835ba0217c858705c64c319c5ee 246 SMART SM00967 5 81 4.1E-18 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 A6A12_RS12515 8cbb2835ba0217c858705c64c319c5ee 246 Gene3D G3DSA:3.30.1330.30 1 76 8.5E-16 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like A6A12_RS12515 8cbb2835ba0217c858705c64c319c5ee 246 SUPERFAMILY SSF75217 69 244 5.82E-49 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases A6A12_RS12500 fc988a83ec24646bf55f6026bb6eff44 200 Pfam PF00573 Ribosomal protein L4/L1 family 12 197 1.5E-65 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 A6A12_RS12500 fc988a83ec24646bf55f6026bb6eff44 200 SUPERFAMILY SSF52166 8 199 1.83E-73 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 A6A12_RS12500 fc988a83ec24646bf55f6026bb6eff44 200 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 12 197 5.8E-76 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12500 fc988a83ec24646bf55f6026bb6eff44 200 Gene3D G3DSA:3.40.1370.10 2 137 1.9E-48 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 A6A12_RS12500 fc988a83ec24646bf55f6026bb6eff44 200 Gene3D G3DSA:3.40.1370.10 138 198 5.9E-11 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 A6A12_RS12500 fc988a83ec24646bf55f6026bb6eff44 200 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 3 200 33.88 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS09935 265bba65c7788f33e1b89979bf40d4d2 154 SUPERFAMILY SSF53254 1 153 4.52E-21 T 28-03-2018 IPR029033 Histidine phosphatase superfamily A6A12_RS09935 265bba65c7788f33e1b89979bf40d4d2 154 SMART SM00855 2 116 5.2E-6 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A6A12_RS09935 265bba65c7788f33e1b89979bf40d4d2 154 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 75 1.8E-9 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 A6A12_RS09935 265bba65c7788f33e1b89979bf40d4d2 154 PIRSF PIRSF000709 1 87 0.0055 T 28-03-2018 A6A12_RS09935 265bba65c7788f33e1b89979bf40d4d2 154 Gene3D G3DSA:3.40.50.1240 1 154 7.2E-21 T 28-03-2018 IPR029033 Histidine phosphatase superfamily A6A12_RS09935 265bba65c7788f33e1b89979bf40d4d2 154 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 1 154 1.3E-35 T 28-03-2018 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0008969 A6A12_RS10095 054b997aec7ec5b1f6a8133644948cd0 149 SUPERFAMILY SSF46785 5 135 8.86E-44 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS10095 054b997aec7ec5b1f6a8133644948cd0 149 Gene3D G3DSA:1.10.10.10 4 88 4.8E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS10095 054b997aec7ec5b1f6a8133644948cd0 149 Pfam PF01475 Ferric uptake regulator family 11 130 1.2E-46 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A6A12_RS02915 e190e9fa0e10f244efd645456abb424f 157 Pfam PF03449 Transcription elongation factor, N-terminal 4 73 5.1E-24 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A6A12_RS02915 e190e9fa0e10f244efd645456abb424f 157 PIRSF PIRSF006092 1 157 1.8E-44 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 A6A12_RS02915 e190e9fa0e10f244efd645456abb424f 157 Gene3D G3DSA:1.10.287.180 3 75 9.9E-26 T 28-03-2018 A6A12_RS02915 e190e9fa0e10f244efd645456abb424f 157 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 47 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A6A12_RS02915 e190e9fa0e10f244efd645456abb424f 157 SUPERFAMILY SSF54534 81 156 1.31E-22 T 28-03-2018 A6A12_RS02915 e190e9fa0e10f244efd645456abb424f 157 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 120 136 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 A6A12_RS02915 e190e9fa0e10f244efd645456abb424f 157 SUPERFAMILY SSF46557 2 75 9.29E-25 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 A6A12_RS02915 e190e9fa0e10f244efd645456abb424f 157 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 155 7.9E-51 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 A6A12_RS02915 e190e9fa0e10f244efd645456abb424f 157 Gene3D G3DSA:3.10.50.30 76 157 4.4E-26 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A6A12_RS02915 e190e9fa0e10f244efd645456abb424f 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 82 156 1.1E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A6A12_RS02915 e190e9fa0e10f244efd645456abb424f 157 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 155 31.068 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 A6A12_RS03535 5fc6a8ff29f231ba69b1c485528ed496 431 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 276 283 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A6A12_RS03535 5fc6a8ff29f231ba69b1c485528ed496 431 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 110 422 3.2E-102 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 A6A12_RS03535 5fc6a8ff29f231ba69b1c485528ed496 431 PIRSF PIRSF036388 1 431 2.6E-223 T 28-03-2018 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 A6A12_RS03535 5fc6a8ff29f231ba69b1c485528ed496 431 SUPERFAMILY SSF53187 105 428 3.11E-100 T 28-03-2018 A6A12_RS03535 5fc6a8ff29f231ba69b1c485528ed496 431 Gene3D G3DSA:3.40.630.10 94 431 1.9E-110 T 28-03-2018 A6A12_RS03535 5fc6a8ff29f231ba69b1c485528ed496 431 PRINTS PR00481 Cytosol aminopeptidase signature 272 292 1.4E-45 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A6A12_RS03535 5fc6a8ff29f231ba69b1c485528ed496 431 PRINTS PR00481 Cytosol aminopeptidase signature 191 208 1.4E-45 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A6A12_RS03535 5fc6a8ff29f231ba69b1c485528ed496 431 PRINTS PR00481 Cytosol aminopeptidase signature 250 271 1.4E-45 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A6A12_RS03535 5fc6a8ff29f231ba69b1c485528ed496 431 PRINTS PR00481 Cytosol aminopeptidase signature 213 234 1.4E-45 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A6A12_RS03535 5fc6a8ff29f231ba69b1c485528ed496 431 PRINTS PR00481 Cytosol aminopeptidase signature 300 315 1.4E-45 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 A6A12_RS03535 5fc6a8ff29f231ba69b1c485528ed496 431 Pfam PF12404 Peptidase 5 82 3.5E-32 T 28-03-2018 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 A6A12_RS06505 19dfa4756483299928dbdd78e4147fc7 255 SUPERFAMILY SSF52540 14 248 1.9E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS06505 19dfa4756483299928dbdd78e4147fc7 255 PIRSF PIRSF039085 11 254 2.6E-111 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A6A12_RS06505 19dfa4756483299928dbdd78e4147fc7 255 Pfam PF00005 ABC transporter 30 178 1.0E-39 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS06505 19dfa4756483299928dbdd78e4147fc7 255 SMART SM00382 39 226 2.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS06505 19dfa4756483299928dbdd78e4147fc7 255 Gene3D G3DSA:3.40.50.300 11 254 5.8E-76 T 28-03-2018 A6A12_RS06505 19dfa4756483299928dbdd78e4147fc7 255 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS00080 76d925086a222ae1b3e1f6154b2d2509 326 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 3 326 4.4E-138 T 28-03-2018 IPR014188 Acrylyl-CoA reductase AcuI A6A12_RS00080 76d925086a222ae1b3e1f6154b2d2509 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 87 4.2E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A6A12_RS00080 76d925086a222ae1b3e1f6154b2d2509 326 Pfam PF00107 Zinc-binding dehydrogenase 159 275 1.6E-12 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A6A12_RS00080 76d925086a222ae1b3e1f6154b2d2509 326 Gene3D G3DSA:3.90.180.10 1 139 1.2E-26 T 28-03-2018 A6A12_RS00080 76d925086a222ae1b3e1f6154b2d2509 326 SUPERFAMILY SSF51735 116 292 5.51E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS00080 76d925086a222ae1b3e1f6154b2d2509 326 Gene3D G3DSA:3.40.50.720 140 318 7.6E-21 T 28-03-2018 A6A12_RS00080 76d925086a222ae1b3e1f6154b2d2509 326 SMART SM00829 13 324 2.5E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A6A12_RS00080 76d925086a222ae1b3e1f6154b2d2509 326 SUPERFAMILY SSF50129 2 145 4.87E-43 T 28-03-2018 IPR011032 GroES-like A6A12_RS00540 d36044febfea31f5fee2e3aaed8241ea 392 SMART SM00963 93 173 2.4E-26 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A6A12_RS00540 d36044febfea31f5fee2e3aaed8241ea 392 Gene3D G3DSA:3.40.50.300 187 390 1.1E-40 T 28-03-2018 A6A12_RS00540 d36044febfea31f5fee2e3aaed8241ea 392 SMART SM00962 188 389 8.7E-122 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A6A12_RS00540 d36044febfea31f5fee2e3aaed8241ea 392 Pfam PF00448 SRP54-type protein, GTPase domain 189 388 4.7E-78 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A6A12_RS00540 d36044febfea31f5fee2e3aaed8241ea 392 Pfam PF02881 SRP54-type protein, helical bundle domain 108 169 1.8E-13 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A6A12_RS00540 d36044febfea31f5fee2e3aaed8241ea 392 SMART SM00382 187 388 1.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS00540 d36044febfea31f5fee2e3aaed8241ea 392 Gene3D G3DSA:1.20.120.140 87 186 1.5E-23 T 28-03-2018 A6A12_RS00540 d36044febfea31f5fee2e3aaed8241ea 392 SUPERFAMILY SSF52540 185 389 1.12E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS00540 d36044febfea31f5fee2e3aaed8241ea 392 SUPERFAMILY SSF47364 88 167 5.1E-22 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A6A12_RS00540 d36044febfea31f5fee2e3aaed8241ea 392 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 116 388 1.9E-115 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A6A12_RS00540 d36044febfea31f5fee2e3aaed8241ea 392 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 116 389 64.535 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A6A12_RS00540 d36044febfea31f5fee2e3aaed8241ea 392 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 362 375 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A6A12_RS04960 bdcc8504cb1da0e58710da09fdda4e08 134 Gene3D G3DSA:2.170.150.20 1 134 1.0E-55 T 28-03-2018 A6A12_RS04960 bdcc8504cb1da0e58710da09fdda4e08 134 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 11 131 9.9E-53 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A6A12_RS04960 bdcc8504cb1da0e58710da09fdda4e08 134 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 11 134 36.373 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A6A12_RS04960 bdcc8504cb1da0e58710da09fdda4e08 134 SUPERFAMILY SSF51316 10 133 5.75E-55 T 28-03-2018 IPR011057 Mss4-like A6A12_RS04960 bdcc8504cb1da0e58710da09fdda4e08 134 Pfam PF01641 SelR domain 15 132 8.7E-51 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 Gene3D G3DSA:3.30.420.40 4 194 1.7E-68 T 28-03-2018 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 TIGRFAM TIGR00016 ackA: acetate kinase 2 396 6.5E-172 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 SUPERFAMILY SSF53067 3 195 3.11E-63 T 28-03-2018 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 PIRSF PIRSF000722 1 397 2.8E-147 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 Pfam PF00871 Acetokinase family 5 390 1.4E-165 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 Hamap MF_00020 Acetate kinase [ackA]. 1 398 187.099 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 PRINTS PR00471 Acetate kinase family signature 172 185 1.3E-45 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 PRINTS PR00471 Acetate kinase family signature 377 389 1.3E-45 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 PRINTS PR00471 Acetate kinase family signature 298 311 1.3E-45 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 PRINTS PR00471 Acetate kinase family signature 321 337 1.3E-45 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 PRINTS PR00471 Acetate kinase family signature 5 16 1.3E-45 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 PRINTS PR00471 Acetate kinase family signature 202 223 1.3E-45 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 SUPERFAMILY SSF53067 157 395 4.49E-85 T 28-03-2018 A6A12_RS09185 4855f6fe943c4ac23101d47bfb0ad148 398 Gene3D G3DSA:3.30.420.40 195 397 1.7E-80 T 28-03-2018 A6A12_RS01060 a6edf678fd04575cf3004db134c235a0 618 SUPERFAMILY SSF50475 3 322 1.33E-121 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A6A12_RS01060 a6edf678fd04575cf3004db134c235a0 618 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 472 566 2.6E-19 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A6A12_RS01060 a6edf678fd04575cf3004db134c235a0 618 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 431 1.1E-161 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A6A12_RS01060 a6edf678fd04575cf3004db134c235a0 618 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 454 1.3E-164 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A6A12_RS01060 a6edf678fd04575cf3004db134c235a0 618 Gene3D G3DSA:1.20.5.570 590 617 4.6E-15 T 28-03-2018 A6A12_RS01060 a6edf678fd04575cf3004db134c235a0 618 SUPERFAMILY SSF143968 473 616 3.01E-34 T 28-03-2018 A6A12_RS01060 a6edf678fd04575cf3004db134c235a0 618 SUPERFAMILY SSF143968 323 463 4.84E-54 T 28-03-2018 A6A12_RS01060 a6edf678fd04575cf3004db134c235a0 618 Gene3D G3DSA:3.40.1670.10 323 469 3.1E-45 T 28-03-2018 A6A12_RS01060 a6edf678fd04575cf3004db134c235a0 618 Gene3D G3DSA:3.40.1670.10 470 589 3.1E-27 T 28-03-2018 A6A12_RS01735 9aaa78371abfcdc266f45bafc64f71bd 157 Hamap MF_00173 Arginine repressor [argR]. 1 156 57.887 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A6A12_RS01735 9aaa78371abfcdc266f45bafc64f71bd 157 Pfam PF01316 Arginine repressor, DNA binding domain 8 75 1.9E-22 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 A6A12_RS01735 9aaa78371abfcdc266f45bafc64f71bd 157 Gene3D G3DSA:3.30.1360.40 77 152 2.4E-26 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 A6A12_RS01735 9aaa78371abfcdc266f45bafc64f71bd 157 Pfam PF02863 Arginine repressor, C-terminal domain 83 148 4.5E-21 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A6A12_RS01735 9aaa78371abfcdc266f45bafc64f71bd 157 TIGRFAM TIGR01529 argR_whole: arginine repressor 11 152 2.3E-42 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A6A12_RS01735 9aaa78371abfcdc266f45bafc64f71bd 157 PRINTS PR01467 Bacterial arginine repressor signature 26 39 2.1E-23 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A6A12_RS01735 9aaa78371abfcdc266f45bafc64f71bd 157 PRINTS PR01467 Bacterial arginine repressor signature 91 104 2.1E-23 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A6A12_RS01735 9aaa78371abfcdc266f45bafc64f71bd 157 PRINTS PR01467 Bacterial arginine repressor signature 43 58 2.1E-23 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A6A12_RS01735 9aaa78371abfcdc266f45bafc64f71bd 157 PRINTS PR01467 Bacterial arginine repressor signature 122 137 2.1E-23 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 A6A12_RS01735 9aaa78371abfcdc266f45bafc64f71bd 157 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 90 147 2.0E-21 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A6A12_RS01735 9aaa78371abfcdc266f45bafc64f71bd 157 SUPERFAMILY SSF55252 83 152 4.19E-19 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 A6A12_RS01735 9aaa78371abfcdc266f45bafc64f71bd 157 SUPERFAMILY SSF46785 6 78 7.98E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS01735 9aaa78371abfcdc266f45bafc64f71bd 157 Gene3D G3DSA:1.10.10.10 9 70 2.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS07725 b86ff89fdc7fcf22a3a6be653f0ad076 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 93 9.6E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS07725 b86ff89fdc7fcf22a3a6be653f0ad076 236 SUPERFAMILY SSF46894 17 94 3.97E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS07725 b86ff89fdc7fcf22a3a6be653f0ad076 236 Gene3D G3DSA:1.10.10.10 4 98 1.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS07725 b86ff89fdc7fcf22a3a6be653f0ad076 236 SMART SM00862 20 93 3.8E-12 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS13790 0d9049eacadb29d4b41bb103692d9a7d 279 SUPERFAMILY SSF53335 9 273 1.54E-95 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS13790 0d9049eacadb29d4b41bb103692d9a7d 279 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 266 41.928 T 28-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 A6A12_RS13790 0d9049eacadb29d4b41bb103692d9a7d 279 Gene3D G3DSA:3.40.50.150 1 279 1.5E-91 T 28-03-2018 A6A12_RS13790 0d9049eacadb29d4b41bb103692d9a7d 279 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 277 1.0E-113 T 28-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 A6A12_RS11320 73ee300a4a45dda781a3fbf55cb48d5d 419 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 1.9E-25 T 28-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 A6A12_RS11320 73ee300a4a45dda781a3fbf55cb48d5d 419 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 5 416 5.8E-150 T 28-03-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 A6A12_RS11320 73ee300a4a45dda781a3fbf55cb48d5d 419 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 197 416 5.9E-72 T 28-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 A6A12_RS11320 73ee300a4a45dda781a3fbf55cb48d5d 419 Pfam PF07670 Nucleoside recognition 95 191 3.1E-7 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A6A12_RS06300 bb8f3baac8f49ffab502a24352e12e34 632 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 165 253 6.3E-15 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A6A12_RS06300 bb8f3baac8f49ffab502a24352e12e34 632 SUPERFAMILY SSF55804 1 146 1.07E-38 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A6A12_RS06300 bb8f3baac8f49ffab502a24352e12e34 632 SUPERFAMILY SSF52794 162 257 4.71E-34 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A6A12_RS06300 bb8f3baac8f49ffab502a24352e12e34 632 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 163 245 1.3E-30 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 A6A12_RS06300 bb8f3baac8f49ffab502a24352e12e34 632 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 276 617 1.2E-86 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 A6A12_RS06300 bb8f3baac8f49ffab502a24352e12e34 632 Gene3D G3DSA:3.40.930.10 1 149 3.8E-38 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 A6A12_RS06300 bb8f3baac8f49ffab502a24352e12e34 632 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 147 2.5E-35 T 28-03-2018 IPR002178 PTS EIIA type-2 domain A6A12_RS06300 bb8f3baac8f49ffab502a24352e12e34 632 Gene3D G3DSA:3.40.50.2300 161 257 1.8E-36 T 28-03-2018 A6A12_RS06300 bb8f3baac8f49ffab502a24352e12e34 632 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 5 131 1.8E-39 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 A6A12_RS06300 bb8f3baac8f49ffab502a24352e12e34 632 Pfam PF02378 Phosphotransferase system, EIIC 289 565 4.5E-15 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 102 297 2.9E-82 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 274 286 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 226 241 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 170 184 1.8E-16 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 98 107 1.8E-16 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 158 170 1.8E-16 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 287 297 1.8E-16 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 198 210 1.8E-16 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 219 231 1.8E-16 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 119 139 1.2E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 226 246 1.2E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 139 158 1.2E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 100 119 1.2E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 271 296 1.2E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 247 268 1.2E-65 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A6A12_RS10170 56066f9bc0a5da41793adbc1574e51a6 299 Pfam PF00813 FliP family 102 293 9.4E-80 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 A6A12_RS05550 f7f410fbef2af629645bdc22a9a1b73a 547 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 60 442 3.0E-53 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A6A12_RS05550 f7f410fbef2af629645bdc22a9a1b73a 547 Gene3D G3DSA:3.90.1150.10 401 531 2.3E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS05550 f7f410fbef2af629645bdc22a9a1b73a 547 SUPERFAMILY SSF53383 29 527 4.75E-110 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS05550 f7f410fbef2af629645bdc22a9a1b73a 547 TIGRFAM TIGR03799 NOD_PanD_pyr: putative pyridoxal-dependent aspartate 1-decarboxylase 6 527 1.9E-294 T 28-03-2018 IPR022517 Aspartate 1-decarboxylase, pyridoxal-dependent A6A12_RS05550 f7f410fbef2af629645bdc22a9a1b73a 547 Gene3D G3DSA:3.40.640.10 112 400 6.5E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS10625 db9df1570a0636d96f5400cf6f3aac88 262 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 261 8.2E-116 T 28-03-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 A6A12_RS10625 db9df1570a0636d96f5400cf6f3aac88 262 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 184 260 3.8E-24 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A6A12_RS10625 db9df1570a0636d96f5400cf6f3aac88 262 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site A6A12_RS10625 db9df1570a0636d96f5400cf6f3aac88 262 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 137 9.9E-40 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G A6A12_RS10625 db9df1570a0636d96f5400cf6f3aac88 262 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 149 244 5.6E-30 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G A6A12_RS10625 db9df1570a0636d96f5400cf6f3aac88 262 Pfam PF00460 Flagella basal body rod protein 5 35 6.9E-11 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A6A12_RS10625 db9df1570a0636d96f5400cf6f3aac88 262 SUPERFAMILY SSF117143 92 223 4.18E-34 T 28-03-2018 A6A12_RS03710 64fdcc243dafd72a3b1996be1951daaf 136 SUPERFAMILY SSF55021 75 134 6.41E-20 T 28-03-2018 A6A12_RS03710 64fdcc243dafd72a3b1996be1951daaf 136 Gene3D G3DSA:3.30.2130.10 5 136 2.6E-28 T 28-03-2018 A6A12_RS03710 64fdcc243dafd72a3b1996be1951daaf 136 Pfam PF10000 ACT domain 8 75 4.5E-26 T 28-03-2018 IPR018717 Domain of unknown function DUF2241 A6A12_RS03710 64fdcc243dafd72a3b1996be1951daaf 136 SUPERFAMILY SSF55021 8 71 2.52E-18 T 28-03-2018 A6A12_RS03710 64fdcc243dafd72a3b1996be1951daaf 136 Pfam PF13840 ACT domain 77 133 6.3E-13 T 28-03-2018 IPR027795 GATS-like ACT domain A6A12_RS02875 4ff18f0dd30c5077eb5cc9b8e4eaa7fd 368 SUPERFAMILY SSF111369 70 283 9.81E-31 T 28-03-2018 A6A12_RS02875 4ff18f0dd30c5077eb5cc9b8e4eaa7fd 368 Gene3D G3DSA:2.40.50.100 171 362 1.1E-8 T 28-03-2018 A6A12_RS02875 4ff18f0dd30c5077eb5cc9b8e4eaa7fd 368 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 63 357 2.6E-46 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A6A12_RS02875 4ff18f0dd30c5077eb5cc9b8e4eaa7fd 368 Gene3D G3DSA:2.40.50.100 75 170 3.6E-9 T 28-03-2018 A6A12_RS02875 4ff18f0dd30c5077eb5cc9b8e4eaa7fd 368 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 78 277 9.4E-24 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A6A12_RS00395 3243be7401dea2ff62fbf9f66abb48b2 276 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 274 6.9E-101 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A6A12_RS00395 3243be7401dea2ff62fbf9f66abb48b2 276 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 276 39.375 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A6A12_RS00395 3243be7401dea2ff62fbf9f66abb48b2 276 Gene3D G3DSA:3.10.310.10 127 263 2.9E-48 T 28-03-2018 A6A12_RS00395 3243be7401dea2ff62fbf9f66abb48b2 276 Gene3D G3DSA:3.10.310.10 1 126 5.6E-48 T 28-03-2018 A6A12_RS00395 3243be7401dea2ff62fbf9f66abb48b2 276 SUPERFAMILY SSF54506 4 132 5.89E-48 T 28-03-2018 A6A12_RS00395 3243be7401dea2ff62fbf9f66abb48b2 276 SUPERFAMILY SSF54506 138 274 2.98E-50 T 28-03-2018 A6A12_RS00395 3243be7401dea2ff62fbf9f66abb48b2 276 Pfam PF01678 Diaminopimelate epimerase 5 124 2.4E-33 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A6A12_RS00395 3243be7401dea2ff62fbf9f66abb48b2 276 Pfam PF01678 Diaminopimelate epimerase 154 269 3.1E-30 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A6A12_RS00395 3243be7401dea2ff62fbf9f66abb48b2 276 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 A6A12_RS14100 eb7cad39193108a434af3ff5690f8295 260 SUPERFAMILY SSF53335 28 258 1.21E-50 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS14100 eb7cad39193108a434af3ff5690f8295 260 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 25 259 37.84 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A6A12_RS14100 eb7cad39193108a434af3ff5690f8295 260 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 45 60 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A6A12_RS14100 eb7cad39193108a434af3ff5690f8295 260 Pfam PF01209 ubiE/COQ5 methyltransferase family 26 259 1.3E-101 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A6A12_RS14100 eb7cad39193108a434af3ff5690f8295 260 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 167 181 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A6A12_RS14100 eb7cad39193108a434af3ff5690f8295 260 Gene3D G3DSA:3.40.50.150 1 259 1.6E-46 T 28-03-2018 A6A12_RS14100 eb7cad39193108a434af3ff5690f8295 260 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 34 259 4.4E-83 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A6A12_RS04805 fdc48a22eecd3e4a2ef75d085735dd7f 252 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 65 80 - T 28-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS04805 fdc48a22eecd3e4a2ef75d085735dd7f 252 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 5 251 2.3E-109 T 28-03-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 A6A12_RS04805 fdc48a22eecd3e4a2ef75d085735dd7f 252 Pfam PF01048 Phosphorylase superfamily 20 246 1.4E-39 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A6A12_RS04805 fdc48a22eecd3e4a2ef75d085735dd7f 252 SUPERFAMILY SSF53167 4 251 1.44E-71 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A6A12_RS04805 fdc48a22eecd3e4a2ef75d085735dd7f 252 Gene3D G3DSA:3.40.50.1580 2 252 2.3E-55 T 28-03-2018 A6A12_RS06765 938dc54bd678c5928a3d3e51dbad75dd 378 SMART SM00382 42 225 1.4E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS06765 938dc54bd678c5928a3d3e51dbad75dd 378 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS06765 938dc54bd678c5928a3d3e51dbad75dd 378 SUPERFAMILY SSF50331 250 373 3.17E-9 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A6A12_RS06765 938dc54bd678c5928a3d3e51dbad75dd 378 Gene3D G3DSA:3.40.50.300 13 272 9.0E-76 T 28-03-2018 A6A12_RS06765 938dc54bd678c5928a3d3e51dbad75dd 378 Pfam PF00005 ABC transporter 35 174 1.0E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS06765 938dc54bd678c5928a3d3e51dbad75dd 378 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 48 372 3.4E-156 T 28-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 A6A12_RS06765 938dc54bd678c5928a3d3e51dbad75dd 378 SUPERFAMILY SSF52540 18 257 4.23E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS06765 938dc54bd678c5928a3d3e51dbad75dd 378 Pfam PF08402 TOBE domain 292 372 1.6E-10 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A6A12_RS02870 e62230bdf490f7bc4a05709487b2c614 113 Gene3D G3DSA:2.60.300.12 8 113 2.0E-36 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A6A12_RS02870 e62230bdf490f7bc4a05709487b2c614 113 Pfam PF01521 Iron-sulphur cluster biosynthesis 8 108 1.2E-17 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A6A12_RS02870 e62230bdf490f7bc4a05709487b2c614 113 SUPERFAMILY SSF89360 7 99 3.53E-29 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A6A12_RS02870 e62230bdf490f7bc4a05709487b2c614 113 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 94 111 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 A6A12_RS02870 e62230bdf490f7bc4a05709487b2c614 113 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 9 113 3.4E-36 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 A6A12_RS02870 e62230bdf490f7bc4a05709487b2c614 113 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 113 35.507 T 28-03-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 A6A12_RS12525 5ba9ce36d2dcc001589e8720f1b6ba55 211 Pfam PF08238 Sel1 repeat 108 143 1.7E-5 T 28-03-2018 IPR006597 Sel1-like repeat A6A12_RS12525 5ba9ce36d2dcc001589e8720f1b6ba55 211 Pfam PF08238 Sel1 repeat 76 106 0.025 T 28-03-2018 IPR006597 Sel1-like repeat A6A12_RS12525 5ba9ce36d2dcc001589e8720f1b6ba55 211 SUPERFAMILY SSF81901 64 179 5.36E-22 T 28-03-2018 A6A12_RS12525 5ba9ce36d2dcc001589e8720f1b6ba55 211 SMART SM00671 144 179 34.0 T 28-03-2018 IPR006597 Sel1-like repeat A6A12_RS12525 5ba9ce36d2dcc001589e8720f1b6ba55 211 SMART SM00671 72 107 0.015 T 28-03-2018 IPR006597 Sel1-like repeat A6A12_RS12525 5ba9ce36d2dcc001589e8720f1b6ba55 211 SMART SM00671 108 143 2.9E-6 T 28-03-2018 IPR006597 Sel1-like repeat A6A12_RS12525 5ba9ce36d2dcc001589e8720f1b6ba55 211 Gene3D G3DSA:2.60.40.1180 121 211 5.3E-14 T 28-03-2018 A6A12_RS12525 5ba9ce36d2dcc001589e8720f1b6ba55 211 Gene3D G3DSA:2.60.40.1180 43 120 4.0E-11 T 28-03-2018 A6A12_RS07980 22e8ed11ae20195d52f63eb74652789e 75 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 28-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 A6A12_RS07980 22e8ed11ae20195d52f63eb74652789e 75 Gene3D G3DSA:3.40.30.10 1 75 8.3E-14 T 28-03-2018 A6A12_RS07980 22e8ed11ae20195d52f63eb74652789e 75 Pfam PF00462 Glutaredoxin 4 59 1.5E-10 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A6A12_RS07980 22e8ed11ae20195d52f63eb74652789e 75 SUPERFAMILY SSF52833 3 69 5.55E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS01560 75674de07f72c7cdf8519ff0872ab88f 217 SUPERFAMILY SSF46894 142 213 9.52E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS01560 75674de07f72c7cdf8519ff0872ab88f 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 211 9.0E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS01560 75674de07f72c7cdf8519ff0872ab88f 217 Gene3D G3DSA:1.10.10.10 119 217 4.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS01560 75674de07f72c7cdf8519ff0872ab88f 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 6.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS01560 75674de07f72c7cdf8519ff0872ab88f 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 6.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS01560 75674de07f72c7cdf8519ff0872ab88f 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 6.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS01560 75674de07f72c7cdf8519ff0872ab88f 217 SMART SM00421 154 211 4.9E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A6A12_RS10825 e75b71d30bce28601b3d9f7f66c84922 436 Pfam PF01171 PP-loop family 22 199 1.2E-56 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A6A12_RS10825 e75b71d30bce28601b3d9f7f66c84922 436 SUPERFAMILY SSF52402 18 233 1.01E-58 T 28-03-2018 A6A12_RS10825 e75b71d30bce28601b3d9f7f66c84922 436 Pfam PF11734 TilS substrate C-terminal domain 365 434 5.2E-21 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A6A12_RS10825 e75b71d30bce28601b3d9f7f66c84922 436 SUPERFAMILY SSF82829 234 318 1.29E-23 T 28-03-2018 A6A12_RS10825 e75b71d30bce28601b3d9f7f66c84922 436 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 8 307 22.532 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A6A12_RS10825 e75b71d30bce28601b3d9f7f66c84922 436 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 22 203 1.5E-52 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A6A12_RS10825 e75b71d30bce28601b3d9f7f66c84922 436 SUPERFAMILY SSF56037 322 434 2.62E-26 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 A6A12_RS10825 e75b71d30bce28601b3d9f7f66c84922 436 Pfam PF09179 TilS substrate binding domain 248 315 7.7E-19 T 28-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A6A12_RS10825 e75b71d30bce28601b3d9f7f66c84922 436 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 365 408 8.3E-15 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A6A12_RS10825 e75b71d30bce28601b3d9f7f66c84922 436 SMART SM00977 365 434 2.8E-22 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 A6A12_RS10825 e75b71d30bce28601b3d9f7f66c84922 436 Gene3D G3DSA:3.40.50.620 18 247 9.5E-38 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS11035 7c08aa23eb4967f53a7135b7870afca5 354 SUPERFAMILY SSF100879 245 353 2.35E-20 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A6A12_RS11035 7c08aa23eb4967f53a7135b7870afca5 354 Pfam PF00817 impB/mucB/samB family 11 158 8.4E-47 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A6A12_RS11035 7c08aa23eb4967f53a7135b7870afca5 354 Hamap MF_01113 DNA polymerase IV [dinB]. 5 353 36.188 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 A6A12_RS11035 7c08aa23eb4967f53a7135b7870afca5 354 Pfam PF11799 impB/mucB/samB family C-terminal domain 240 340 3.3E-5 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A6A12_RS11035 7c08aa23eb4967f53a7135b7870afca5 354 SUPERFAMILY SSF56672 5 238 1.33E-90 T 28-03-2018 A6A12_RS11035 7c08aa23eb4967f53a7135b7870afca5 354 Gene3D G3DSA:1.10.150.20 175 246 1.5E-17 T 28-03-2018 A6A12_RS11035 7c08aa23eb4967f53a7135b7870afca5 354 Gene3D G3DSA:3.30.1490.100 247 353 1.7E-18 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 A6A12_RS11035 7c08aa23eb4967f53a7135b7870afca5 354 Gene3D G3DSA:3.30.70.270 45 115 1.0E-24 T 28-03-2018 A6A12_RS11035 7c08aa23eb4967f53a7135b7870afca5 354 Gene3D G3DSA:3.30.70.270 116 174 8.5E-21 T 28-03-2018 A6A12_RS09120 bca6c7fd44094000bceab8f6f719a91a 267 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 13 267 31.574 T 28-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 A6A12_RS09120 bca6c7fd44094000bceab8f6f719a91a 267 Pfam PF08241 Methyltransferase domain 58 150 3.6E-26 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A6A12_RS09120 bca6c7fd44094000bceab8f6f719a91a 267 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 21 266 2.5E-67 T 28-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 A6A12_RS09120 bca6c7fd44094000bceab8f6f719a91a 267 SUPERFAMILY SSF53335 19 198 2.74E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS09120 bca6c7fd44094000bceab8f6f719a91a 267 Gene3D G3DSA:3.40.50.150 5 266 3.9E-35 T 28-03-2018 A6A12_RS13200 4bc54c554c5aa27245a3d8787ba160df 372 Gene3D G3DSA:3.40.50.2000 20 183 4.8E-11 T 28-03-2018 A6A12_RS13200 4bc54c554c5aa27245a3d8787ba160df 372 Gene3D G3DSA:3.40.50.2000 184 353 1.7E-27 T 28-03-2018 A6A12_RS13200 4bc54c554c5aa27245a3d8787ba160df 372 Pfam PF13477 Glycosyl transferase 4-like 3 147 1.9E-17 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A6A12_RS13200 4bc54c554c5aa27245a3d8787ba160df 372 Pfam PF00534 Glycosyl transferases group 1 186 342 6.2E-20 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 A6A12_RS13200 4bc54c554c5aa27245a3d8787ba160df 372 SUPERFAMILY SSF53756 20 370 4.13E-51 T 28-03-2018 A6A12_RS11190 e4d9cc8812de746d3b200e7b04a7f8db 297 Gene3D G3DSA:3.40.190.10 179 269 2.8E-18 T 28-03-2018 A6A12_RS11190 e4d9cc8812de746d3b200e7b04a7f8db 297 SUPERFAMILY SSF46785 5 113 1.72E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS11190 e4d9cc8812de746d3b200e7b04a7f8db 297 SUPERFAMILY SSF53850 92 294 1.41E-42 T 28-03-2018 A6A12_RS11190 e4d9cc8812de746d3b200e7b04a7f8db 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 5.6E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS11190 e4d9cc8812de746d3b200e7b04a7f8db 297 Gene3D G3DSA:1.10.10.10 1 86 4.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS11190 e4d9cc8812de746d3b200e7b04a7f8db 297 Gene3D G3DSA:3.40.190.10 91 178 2.3E-20 T 28-03-2018 A6A12_RS11190 e4d9cc8812de746d3b200e7b04a7f8db 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 8.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS11190 e4d9cc8812de746d3b200e7b04a7f8db 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 8.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS11190 e4d9cc8812de746d3b200e7b04a7f8db 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 8.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS11190 e4d9cc8812de746d3b200e7b04a7f8db 297 Pfam PF03466 LysR substrate binding domain 90 293 8.9E-48 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS07205 1564845bf1f54666ed9adf1b0a393cd6 632 SUPERFAMILY SSF53067 8 201 2.91E-27 T 28-03-2018 A6A12_RS07205 1564845bf1f54666ed9adf1b0a393cd6 632 Pfam PF00012 Hsp70 protein 10 340 4.8E-17 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS07205 1564845bf1f54666ed9adf1b0a393cd6 632 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 12 19 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A6A12_RS07205 1564845bf1f54666ed9adf1b0a393cd6 632 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 220 233 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 A6A12_RS07205 1564845bf1f54666ed9adf1b0a393cd6 632 PRINTS PR00301 70kDa heat shock protein signature 159 179 8.3E-7 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS07205 1564845bf1f54666ed9adf1b0a393cd6 632 PRINTS PR00301 70kDa heat shock protein signature 226 236 8.3E-7 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS07205 1564845bf1f54666ed9adf1b0a393cd6 632 PRINTS PR00301 70kDa heat shock protein signature 8 21 8.3E-7 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 A6A12_RS07205 1564845bf1f54666ed9adf1b0a393cd6 632 Gene3D G3DSA:3.30.420.40 8 224 1.6E-33 T 28-03-2018 A6A12_RS07205 1564845bf1f54666ed9adf1b0a393cd6 632 SUPERFAMILY SSF53067 215 365 3.99E-26 T 28-03-2018 A6A12_RS07205 1564845bf1f54666ed9adf1b0a393cd6 632 SUPERFAMILY SSF53067 418 477 3.99E-26 T 28-03-2018 A6A12_RS07205 1564845bf1f54666ed9adf1b0a393cd6 632 Gene3D G3DSA:3.30.420.40 225 450 6.5E-17 T 28-03-2018 A6A12_RS07325 7ff67e565ddc1a3ab402dbc17cf921be 341 Pfam PF05128 Domain of unknown function (DUF697) 177 335 2.0E-50 T 28-03-2018 IPR021147 Protein of unknown function DUF697 A6A12_RS07325 7ff67e565ddc1a3ab402dbc17cf921be 341 TIGRFAM TIGR01620 hyp_HI0043: TIGR01620 family protein 68 334 7.7E-71 T 28-03-2018 IPR006507 Uncharacterised protein family UPF0283 A6A12_RS09165 bb29c8a1cc47de72536271485f816066 264 Gene3D G3DSA:3.40.50.300 1 254 1.8E-48 T 28-03-2018 A6A12_RS09165 bb29c8a1cc47de72536271485f816066 264 SUPERFAMILY SSF52540 2 235 3.06E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09165 bb29c8a1cc47de72536271485f816066 264 Pfam PF00005 ABC transporter 22 177 9.3E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS09165 bb29c8a1cc47de72536271485f816066 264 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS09165 bb29c8a1cc47de72536271485f816066 264 SMART SM00382 31 226 8.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS04175 697047c0ac46a7d1ff7f419a8ba33a92 544 SMART SM00304 254 306 1.0E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS04175 697047c0ac46a7d1ff7f419a8ba33a92 544 Gene3D G3DSA:1.10.287.130 297 369 1.1E-10 T 28-03-2018 A6A12_RS04175 697047c0ac46a7d1ff7f419a8ba33a92 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 468 3.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS04175 697047c0ac46a7d1ff7f419a8ba33a92 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 482 3.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS04175 697047c0ac46a7d1ff7f419a8ba33a92 544 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 507 3.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A6A12_RS04175 697047c0ac46a7d1ff7f419a8ba33a92 544 Gene3D G3DSA:3.30.565.10 388 543 2.2E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS04175 697047c0ac46a7d1ff7f419a8ba33a92 544 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 420 529 6.6E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS04175 697047c0ac46a7d1ff7f419a8ba33a92 544 Pfam PF00512 His Kinase A (phospho-acceptor) domain 307 369 2.6E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS04175 697047c0ac46a7d1ff7f419a8ba33a92 544 SMART SM00388 307 373 3.7E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS04175 697047c0ac46a7d1ff7f419a8ba33a92 544 SUPERFAMILY SSF47384 290 371 2.35E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 A6A12_RS04175 697047c0ac46a7d1ff7f419a8ba33a92 544 SUPERFAMILY SSF55874 379 531 1.96E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS04175 697047c0ac46a7d1ff7f419a8ba33a92 544 SMART SM00387 419 531 7.0E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS05970 309ddf6b3d3a64f93595734130ba362d 447 SUPERFAMILY SSF161070 6 447 2.48E-117 T 28-03-2018 A6A12_RS05970 309ddf6b3d3a64f93595734130ba362d 447 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 43 62 3.0E-8 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS05970 309ddf6b3d3a64f93595734130ba362d 447 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 14 35 3.0E-8 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS05970 309ddf6b3d3a64f93595734130ba362d 447 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 427 447 3.0E-8 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS05970 309ddf6b3d3a64f93595734130ba362d 447 Pfam PF00209 Sodium:neurotransmitter symporter family 146 447 2.4E-28 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS05970 309ddf6b3d3a64f93595734130ba362d 447 Pfam PF00209 Sodium:neurotransmitter symporter family 6 117 1.4E-18 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 Gene3D G3DSA:3.40.1060.10 156 290 7.3E-44 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 SUPERFAMILY SSF53732 4 467 1.96E-166 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 Pfam PF00330 Aconitase family (aconitate hydratase) 9 459 4.2E-161 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 ProSitePatterns PS00450 Aconitase family signature 1. 341 357 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 3 468 60.808 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 Gene3D G3DSA:3.30.499.10 305 472 3.6E-54 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 ProSitePatterns PS01244 Aconitase family signature 2. 401 414 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 PRINTS PR00415 Aconitase family signature 197 210 1.2E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 PRINTS PR00415 Aconitase family signature 211 224 1.2E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 PRINTS PR00415 Aconitase family signature 345 356 1.2E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 PRINTS PR00415 Aconitase family signature 121 134 1.2E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 PRINTS PR00415 Aconitase family signature 135 150 1.2E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 PRINTS PR00415 Aconitase family signature 110 118 1.2E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 PRINTS PR00415 Aconitase family signature 401 414 1.2E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 PRINTS PR00415 Aconitase family signature 84 97 1.2E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 PRINTS PR00415 Aconitase family signature 288 302 1.2E-49 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 Gene3D G3DSA:3.30.499.10 1 155 5.5E-39 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11945 d21e4a4ba979eae45a912149add8b2c1 473 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 467 1.6E-265 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 A6A12_RS07940 226e1d8d16264e4f341d3715d6060d77 382 Gene3D G3DSA:3.40.1710.10 40 198 3.7E-24 T 28-03-2018 A6A12_RS07940 226e1d8d16264e4f341d3715d6060d77 382 Pfam PF12698 ABC-2 family transporter protein 19 354 1.4E-42 T 28-03-2018 A6A12_RS08785 6015c746ac467efbc3cf7585302bc03f 179 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 76 179 2.2E-44 T 28-03-2018 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 A6A12_RS08785 6015c746ac467efbc3cf7585302bc03f 179 SUPERFAMILY SSF103088 70 179 2.22E-33 T 28-03-2018 IPR006665 OmpA-like domain A6A12_RS08785 6015c746ac467efbc3cf7585302bc03f 179 Pfam PF00691 OmpA family 78 173 7.1E-22 T 28-03-2018 IPR006665 OmpA-like domain A6A12_RS08785 6015c746ac467efbc3cf7585302bc03f 179 ProSitePatterns PS01068 OmpA-like domain. 111 155 - T 28-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 A6A12_RS08785 6015c746ac467efbc3cf7585302bc03f 179 Gene3D G3DSA:3.30.1330.60 23 179 9.3E-34 T 28-03-2018 IPR006665 OmpA-like domain A6A12_RS08785 6015c746ac467efbc3cf7585302bc03f 179 PRINTS PR01021 OMPA domain signature 109 124 8.4E-16 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A6A12_RS08785 6015c746ac467efbc3cf7585302bc03f 179 PRINTS PR01021 OMPA domain signature 79 101 8.4E-16 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A6A12_RS08785 6015c746ac467efbc3cf7585302bc03f 179 PRINTS PR01021 OMPA domain signature 124 140 8.4E-16 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A6A12_RS03210 b25614400c37701a1ccbc95995951c55 316 Gene3D G3DSA:3.40.50.1220 63 302 2.8E-4 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A6A12_RS03210 b25614400c37701a1ccbc95995951c55 316 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 38.069 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 A6A12_RS03210 b25614400c37701a1ccbc95995951c55 316 Pfam PF02401 LytB protein 3 284 8.9E-92 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 A6A12_RS03210 b25614400c37701a1ccbc95995951c55 316 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 286 5.7E-97 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 A6A12_RS10165 ab53ce4cbfecd489b4e3196176c5c37f 89 PIRSF PIRSF004669 1 89 2.0E-29 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A6A12_RS10165 ab53ce4cbfecd489b4e3196176c5c37f 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 4.5E-16 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A6A12_RS10165 ab53ce4cbfecd489b4e3196176c5c37f 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 4.5E-16 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A6A12_RS10165 ab53ce4cbfecd489b4e3196176c5c37f 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 4.5E-16 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A6A12_RS10165 ab53ce4cbfecd489b4e3196176c5c37f 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 1.2E-27 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 A6A12_RS10165 ab53ce4cbfecd489b4e3196176c5c37f 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 2.3E-32 T 28-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 Pfam PF01464 Transglycosylase SLT domain 124 223 1.8E-21 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 SUPERFAMILY SSF54106 414 458 1.26E-11 T 28-03-2018 IPR018392 LysM domain A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 SMART SM00257 414 458 2.5E-14 T 28-03-2018 IPR018392 LysM domain A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 SMART SM00257 471 515 2.1E-11 T 28-03-2018 IPR018392 LysM domain A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 SMART SM00257 340 383 2.1E-13 T 28-03-2018 IPR018392 LysM domain A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 130 158 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 Gene3D G3DSA:3.10.350.10 338 385 1.1E-12 T 28-03-2018 A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 SUPERFAMILY SSF54106 339 383 2.35E-11 T 28-03-2018 IPR018392 LysM domain A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 SUPERFAMILY SSF54106 470 515 5.36E-10 T 28-03-2018 IPR018392 LysM domain A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 Pfam PF01476 LysM domain 472 514 7.0E-13 T 28-03-2018 IPR018392 LysM domain A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 Pfam PF01476 LysM domain 415 458 3.4E-13 T 28-03-2018 IPR018392 LysM domain A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 Pfam PF01476 LysM domain 341 383 7.8E-11 T 28-03-2018 IPR018392 LysM domain A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 SUPERFAMILY SSF53955 109 260 9.0E-40 T 28-03-2018 IPR023346 Lysozyme-like domain A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 Gene3D G3DSA:1.10.530.10 17 255 3.5E-34 T 28-03-2018 A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 Gene3D G3DSA:3.10.350.10 410 463 6.2E-15 T 28-03-2018 A6A12_RS10800 a93e4bd9c9d0ba0fceaaf56e828107f5 523 Gene3D G3DSA:3.10.350.10 467 520 9.1E-13 T 28-03-2018 A6A12_RS13580 5c511e57c0b06f7ac7ff9dd66897848a 118 Pfam PF07878 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 8 44 1.1E-7 T 28-03-2018 IPR012869 CopG-like ribbon-helix-helix domain A6A12_RS13580 5c511e57c0b06f7ac7ff9dd66897848a 118 Gene3D G3DSA:1.10.1220.10 4 115 1.6E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A6A12_RS08085 29c3babb1b8fe97569ba0ab989a31385 474 PIRSF PIRSF000977 1 474 1.4E-195 T 28-03-2018 IPR023607 Exodeoxyribonuclease I GO:0004529 A6A12_RS08085 29c3babb1b8fe97569ba0ab989a31385 474 Pfam PF00929 Exonuclease 11 191 2.0E-24 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS08085 29c3babb1b8fe97569ba0ab989a31385 474 Pfam PF08411 Exonuclease C-terminal 210 470 1.9E-100 T 28-03-2018 IPR013620 Exodeoxyribonuclease I, C-terminal GO:0006281|GO:0008852 A6A12_RS08085 29c3babb1b8fe97569ba0ab989a31385 474 SUPERFAMILY SSF53098 6 472 1.93E-136 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS08085 29c3babb1b8fe97569ba0ab989a31385 474 Gene3D G3DSA:3.30.420.10 1 199 6.1E-27 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS08085 29c3babb1b8fe97569ba0ab989a31385 474 SMART SM00479 8 201 0.0026 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS10755 6309c4e99ef550d918bea8148594d955 213 Pfam PF00551 Formyl transferase 3 181 2.5E-60 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A6A12_RS10755 6309c4e99ef550d918bea8148594d955 213 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 192 2.8E-74 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A6A12_RS10755 6309c4e99ef550d918bea8148594d955 213 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A6A12_RS10755 6309c4e99ef550d918bea8148594d955 213 SUPERFAMILY SSF53328 4 200 1.3E-63 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A6A12_RS10755 6309c4e99ef550d918bea8148594d955 213 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 30.589 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 A6A12_RS10755 6309c4e99ef550d918bea8148594d955 213 Gene3D G3DSA:3.40.50.170 2 204 2.2E-66 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A6A12_RS13910 ee51cd5b7280b88bb69f58d62712dae0 104 Gene3D G3DSA:1.10.260.40 7 103 9.2E-20 T 28-03-2018 A6A12_RS13910 ee51cd5b7280b88bb69f58d62712dae0 104 SMART SM00530 10 69 1.2E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A6A12_RS13910 ee51cd5b7280b88bb69f58d62712dae0 104 Pfam PF12844 Helix-turn-helix domain 10 70 1.6E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A6A12_RS13910 ee51cd5b7280b88bb69f58d62712dae0 104 SUPERFAMILY SSF47413 6 74 5.35E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS03590 f9267c891e079eb10ccae8178a9e9fec 487 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 8 473 1.2E-161 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A6A12_RS03590 f9267c891e079eb10ccae8178a9e9fec 487 SUPERFAMILY SSF51412 217 477 1.83E-123 T 28-03-2018 A6A12_RS03590 f9267c891e079eb10ccae8178a9e9fec 487 SUPERFAMILY SSF51412 1 90 1.83E-123 T 28-03-2018 A6A12_RS03590 f9267c891e079eb10ccae8178a9e9fec 487 Gene3D G3DSA:3.20.20.70 1 484 6.0E-117 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS03590 f9267c891e079eb10ccae8178a9e9fec 487 SUPERFAMILY SSF54631 95 203 4.42E-26 T 28-03-2018 A6A12_RS03590 f9267c891e079eb10ccae8178a9e9fec 487 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 8 486 83.868 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A6A12_RS03590 f9267c891e079eb10ccae8178a9e9fec 487 SMART SM00116 96 144 7.7E-12 T 28-03-2018 IPR000644 CBS domain A6A12_RS03590 f9267c891e079eb10ccae8178a9e9fec 487 SMART SM00116 158 206 5.1E-5 T 28-03-2018 IPR000644 CBS domain A6A12_RS03590 f9267c891e079eb10ccae8178a9e9fec 487 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 295 307 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A6A12_RS03590 f9267c891e079eb10ccae8178a9e9fec 487 Pfam PF00571 CBS domain 96 140 9.8E-10 T 28-03-2018 IPR000644 CBS domain A6A12_RS03590 f9267c891e079eb10ccae8178a9e9fec 487 Pfam PF00571 CBS domain 149 201 1.3E-4 T 28-03-2018 IPR000644 CBS domain A6A12_RS03590 f9267c891e079eb10ccae8178a9e9fec 487 SMART SM01240 7 473 0.0 T 28-03-2018 A6A12_RS03590 f9267c891e079eb10ccae8178a9e9fec 487 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 8 454 1.5E-195 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A6A12_RS03590 f9267c891e079eb10ccae8178a9e9fec 487 PIRSF PIRSF000130 1 487 1.7E-200 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A6A12_RS04365 f99f6770b2ade0594c5745fa258df81e 626 Gene3D G3DSA:3.90.1310.10 34 250 7.9E-57 T 28-03-2018 A6A12_RS04365 f99f6770b2ade0594c5745fa258df81e 626 Pfam PF03717 Penicillin-binding Protein dimerisation domain 65 240 3.8E-51 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A6A12_RS04365 f99f6770b2ade0594c5745fa258df81e 626 Gene3D G3DSA:3.40.710.10 251 625 5.2E-84 T 28-03-2018 A6A12_RS04365 f99f6770b2ade0594c5745fa258df81e 626 Pfam PF00905 Penicillin binding protein transpeptidase domain 272 616 2.5E-72 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A6A12_RS04365 f99f6770b2ade0594c5745fa258df81e 626 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 21 619 1.8E-235 T 28-03-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0016020 A6A12_RS04365 f99f6770b2ade0594c5745fa258df81e 626 SUPERFAMILY SSF56601 255 619 5.27E-94 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A6A12_RS04365 f99f6770b2ade0594c5745fa258df81e 626 SUPERFAMILY SSF56519 57 254 5.23E-57 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 A6A12_RS09895 d13677bbcd991ef40c70bed2232dc796 371 PIRSF PIRSF000876 1 369 3.4E-127 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A6A12_RS09895 d13677bbcd991ef40c70bed2232dc796 371 Gene3D G3DSA:3.40.50.180 173 368 3.4E-68 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A6A12_RS09895 d13677bbcd991ef40c70bed2232dc796 371 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 3 369 38.831 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A6A12_RS09895 d13677bbcd991ef40c70bed2232dc796 371 Gene3D G3DSA:3.40.50.2300 2 148 3.1E-29 T 28-03-2018 A6A12_RS09895 d13677bbcd991ef40c70bed2232dc796 371 SMART SM00448 3 122 3.7E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS09895 d13677bbcd991ef40c70bed2232dc796 371 SUPERFAMILY SSF52738 180 364 1.7E-62 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A6A12_RS09895 d13677bbcd991ef40c70bed2232dc796 371 Pfam PF01339 CheB methylesterase 186 363 3.9E-58 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A6A12_RS09895 d13677bbcd991ef40c70bed2232dc796 371 Pfam PF00072 Response regulator receiver domain 5 109 6.1E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS09895 d13677bbcd991ef40c70bed2232dc796 371 SUPERFAMILY SSF52172 2 109 3.84E-26 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS04755 7d4f5d4a8ec46e9f22022179e82e3c3a 112 SUPERFAMILY SSF47226 2 109 3.01E-19 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS04755 7d4f5d4a8ec46e9f22022179e82e3c3a 112 Gene3D G3DSA:1.20.120.160 1 112 2.2E-12 T 28-03-2018 A6A12_RS04755 7d4f5d4a8ec46e9f22022179e82e3c3a 112 Pfam PF01627 Hpt domain 24 102 2.4E-8 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS13070 82f614ea726068f75c0e44fef5d550db 396 PIRSF PIRSF004925 1 388 7.3E-104 T 28-03-2018 IPR026032 Probable 3-phenylpropionic acid transporter A6A12_RS13070 82f614ea726068f75c0e44fef5d550db 396 SUPERFAMILY SSF103473 8 373 2.09E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain A6A12_RS13070 82f614ea726068f75c0e44fef5d550db 396 Gene3D G3DSA:1.20.1250.20 190 373 6.3E-8 T 28-03-2018 A6A12_RS13070 82f614ea726068f75c0e44fef5d550db 396 Pfam PF12832 MFS_1 like family 13 361 5.5E-40 T 28-03-2018 IPR024989 Major facilitator superfamily associated domain A6A12_RS13070 82f614ea726068f75c0e44fef5d550db 396 Gene3D G3DSA:1.20.1250.20 5 187 1.2E-8 T 28-03-2018 A6A12_RS09325 034fa6bcba62af0af5de2e2166237a64 154 Gene3D G3DSA:3.10.129.10 2 141 8.5E-24 T 28-03-2018 A6A12_RS09325 034fa6bcba62af0af5de2e2166237a64 154 SUPERFAMILY SSF54637 5 142 2.24E-28 T 28-03-2018 IPR029069 HotDog domain A6A12_RS09325 034fa6bcba62af0af5de2e2166237a64 154 PIRSF PIRSF020565 1 154 5.2E-59 T 28-03-2018 IPR016776 3-hydroxylacyl-(acyl carrier protein) dehydratase, predicted A6A12_RS00640 46021b3817ceb3fce99c312137ba37a6 469 Gene3D G3DSA:1.10.150.130 69 213 6.7E-4 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A6A12_RS00640 46021b3817ceb3fce99c312137ba37a6 469 SUPERFAMILY SSF56349 232 450 1.32E-20 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS00640 46021b3817ceb3fce99c312137ba37a6 469 Gene3D G3DSA:1.10.443.10 249 450 4.8E-22 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS00640 46021b3817ceb3fce99c312137ba37a6 469 Pfam PF00589 Phage integrase family 254 444 3.5E-11 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS13995 07a1c1b4f15653af957299116c4eaa15 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 67 1.5E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A6A12_RS13995 07a1c1b4f15653af957299116c4eaa15 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A6A12_RS13995 07a1c1b4f15653af957299116c4eaa15 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A6A12_RS13995 07a1c1b4f15653af957299116c4eaa15 203 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 66 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A6A12_RS13995 07a1c1b4f15653af957299116c4eaa15 203 Gene3D G3DSA:1.10.260.40 52 78 1.8E-4 T 28-03-2018 A6A12_RS13995 07a1c1b4f15653af957299116c4eaa15 203 Gene3D G3DSA:1.10.357.10 79 202 3.3E-5 T 28-03-2018 A6A12_RS13995 07a1c1b4f15653af957299116c4eaa15 203 Pfam PF16295 Tetracycline repressor, C-terminal all-alpha domain 74 201 1.3E-7 T 28-03-2018 IPR032551 HTH-type transcriptional repressor, C-terminal A6A12_RS13995 07a1c1b4f15653af957299116c4eaa15 203 SUPERFAMILY SSF46689 17 94 1.5E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS13995 07a1c1b4f15653af957299116c4eaa15 203 Gene3D G3DSA:1.10.10.60 18 51 1.2E-16 T 28-03-2018 A6A12_RS06660 65227f79a894b0b089d7b342ca1c5723 547 Gene3D G3DSA:3.30.230.10 291 533 1.2E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A6A12_RS06660 65227f79a894b0b089d7b342ca1c5723 547 Pfam PF13654 AAA domain 88 288 1.2E-22 T 28-03-2018 A6A12_RS06660 65227f79a894b0b089d7b342ca1c5723 547 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 397 416 2.0E-11 T 28-03-2018 A6A12_RS06660 65227f79a894b0b089d7b342ca1c5723 547 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 427 446 2.0E-11 T 28-03-2018 A6A12_RS06660 65227f79a894b0b089d7b342ca1c5723 547 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 457 475 2.0E-11 T 28-03-2018 A6A12_RS06660 65227f79a894b0b089d7b342ca1c5723 547 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 314 330 2.0E-11 T 28-03-2018 A6A12_RS06660 65227f79a894b0b089d7b342ca1c5723 547 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 400 502 2.6E-10 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A6A12_RS06660 65227f79a894b0b089d7b342ca1c5723 547 SUPERFAMILY SSF54211 314 506 5.69E-35 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS01705 b75092229cf72ab0fe35a898c5d4625e 267 SUPERFAMILY SSF49785 2 156 1.87E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like A6A12_RS01705 b75092229cf72ab0fe35a898c5d4625e 267 Gene3D G3DSA:2.60.120.260 1 158 3.1E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like A6A12_RS14250 9c10fbc03743c093c1189a86d1fab8f8 431 Gene3D G3DSA:3.20.20.70 175 416 4.5E-34 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS14250 9c10fbc03743c093c1189a86d1fab8f8 431 Pfam PF02581 Thiamine monophosphate synthase 215 398 8.0E-49 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A6A12_RS14250 9c10fbc03743c093c1189a86d1fab8f8 431 SUPERFAMILY SSF51391 204 415 2.62E-56 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A6A12_RS03665 1a883291279956d529852cef7d75163a 215 Pfam PF14187 Domain of unknown function (DUF4310) 6 213 2.0E-102 T 28-03-2018 IPR025456 Protein of unknown function DUF4310 A6A12_RS03665 1a883291279956d529852cef7d75163a 215 TIGRFAM TIGR03579 EF_0833: conserved hypothetical protein EF_0833/AHA_3914 8 215 5.0E-117 T 28-03-2018 IPR025456 Protein of unknown function DUF4310 A6A12_RS05540 44d0f392289e2f0e9d5718b1e87af2ef 413 SUPERFAMILY SSF56796 1 380 1.96E-88 T 28-03-2018 A6A12_RS05540 44d0f392289e2f0e9d5718b1e87af2ef 413 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 372 2.5E-90 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A6A12_RS05540 44d0f392289e2f0e9d5718b1e87af2ef 413 Gene3D G3DSA:3.40.50.1970 8 179 5.2E-38 T 28-03-2018 A6A12_RS05540 44d0f392289e2f0e9d5718b1e87af2ef 413 Gene3D G3DSA:1.20.1090.10 183 388 4.5E-41 T 28-03-2018 A6A12_RS04790 9f8875dccfe9cc683550bf05b2f17be5 321 Gene3D G3DSA:3.30.70.270 151 321 4.1E-43 T 28-03-2018 A6A12_RS04790 9f8875dccfe9cc683550bf05b2f17be5 321 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 149 316 1.1E-42 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS04790 9f8875dccfe9cc683550bf05b2f17be5 321 SUPERFAMILY SSF55785 9 133 4.61E-8 T 28-03-2018 IPR000014 PAS domain A6A12_RS04790 9f8875dccfe9cc683550bf05b2f17be5 321 Pfam PF08448 PAS fold 21 135 8.9E-8 T 28-03-2018 IPR013656 PAS fold-4 A6A12_RS04790 9f8875dccfe9cc683550bf05b2f17be5 321 Pfam PF00990 Diguanylate cyclase, GGDEF domain 154 313 2.7E-41 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS04790 9f8875dccfe9cc683550bf05b2f17be5 321 SUPERFAMILY SSF55073 158 318 3.45E-41 T 28-03-2018 IPR029787 Nucleotide cyclase A6A12_RS04790 9f8875dccfe9cc683550bf05b2f17be5 321 Gene3D G3DSA:3.30.450.20 12 150 5.2E-13 T 28-03-2018 A6A12_RS04790 9f8875dccfe9cc683550bf05b2f17be5 321 SMART SM00267 142 318 3.8E-49 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS09460 99e37ce890c9924a1da54f4fdb090668 299 SUPERFAMILY SSF53850 90 292 2.35E-21 T 28-03-2018 A6A12_RS09460 99e37ce890c9924a1da54f4fdb090668 299 Gene3D G3DSA:1.10.10.10 2 87 2.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09460 99e37ce890c9924a1da54f4fdb090668 299 Pfam PF03466 LysR substrate binding domain 90 295 5.7E-20 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS09460 99e37ce890c9924a1da54f4fdb090668 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 65 1.1E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS09460 99e37ce890c9924a1da54f4fdb090668 299 Gene3D G3DSA:3.40.190.10 88 220 2.0E-11 T 28-03-2018 A6A12_RS09460 99e37ce890c9924a1da54f4fdb090668 299 SUPERFAMILY SSF46785 3 112 2.65E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09460 99e37ce890c9924a1da54f4fdb090668 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS09460 99e37ce890c9924a1da54f4fdb090668 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS09460 99e37ce890c9924a1da54f4fdb090668 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS09525 dff2d5c8176c62e7249f2f6eb2bbace9 132 Pfam PF04134 Protein of unknown function, DUF393 8 116 1.4E-22 T 28-03-2018 IPR007263 Protein of unknown function DUF393 A6A12_RS09555 4ca24569ee351fe2d02371b99d185cd2 572 SUPERFAMILY SSF52518 9 185 4.02E-32 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS09555 4ca24569ee351fe2d02371b99d185cd2 572 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 6 569 32.645 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 A6A12_RS09555 4ca24569ee351fe2d02371b99d185cd2 572 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 12 173 3.4E-30 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 A6A12_RS09555 4ca24569ee351fe2d02371b99d185cd2 572 PIRSF PIRSF004983 3 572 2.2E-182 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 A6A12_RS09555 4ca24569ee351fe2d02371b99d185cd2 572 Pfam PF16582 Middle domain of thiamine pyrophosphate 190 404 1.0E-39 T 28-03-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 A6A12_RS09555 4ca24569ee351fe2d02371b99d185cd2 572 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 415 550 1.2E-6 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A6A12_RS09555 4ca24569ee351fe2d02371b99d185cd2 572 Gene3D G3DSA:3.40.50.1220 221 368 2.5E-20 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A6A12_RS09555 4ca24569ee351fe2d02371b99d185cd2 572 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 12 445 5.1E-136 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 A6A12_RS09555 4ca24569ee351fe2d02371b99d185cd2 572 Gene3D G3DSA:3.40.50.970 369 572 9.2E-17 T 28-03-2018 A6A12_RS09555 4ca24569ee351fe2d02371b99d185cd2 572 Gene3D G3DSA:3.40.50.970 4 210 2.7E-49 T 28-03-2018 A6A12_RS09555 4ca24569ee351fe2d02371b99d185cd2 572 SUPERFAMILY SSF52518 398 556 1.38E-24 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS09555 4ca24569ee351fe2d02371b99d185cd2 572 SUPERFAMILY SSF52467 224 371 1.82E-7 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A6A12_RS05670 13a293981dcb88234d9090c5a01f4894 211 SUPERFAMILY SSF101386 123 210 9.81E-25 T 28-03-2018 A6A12_RS05670 13a293981dcb88234d9090c5a01f4894 211 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 123 210 7.2E-18 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 A6A12_RS05670 13a293981dcb88234d9090c5a01f4894 211 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 120 206 19.619 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A6A12_RS05670 13a293981dcb88234d9090c5a01f4894 211 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 123 206 2.5E-31 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 A6A12_RS05670 13a293981dcb88234d9090c5a01f4894 211 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 38 110 3.9E-33 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A6A12_RS05670 13a293981dcb88234d9090c5a01f4894 211 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 13 211 38.097 T 28-03-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 A6A12_RS05670 13a293981dcb88234d9090c5a01f4894 211 Gene3D G3DSA:1.10.287.1080 119 211 1.3E-20 T 28-03-2018 A6A12_RS05670 13a293981dcb88234d9090c5a01f4894 211 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 61 110 1.0E-22 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 A6A12_RS05670 13a293981dcb88234d9090c5a01f4894 211 SUPERFAMILY SSF141734 14 124 6.15E-47 T 28-03-2018 A6A12_RS13650 0f66cda33fc42e6fde87c04335f00b14 244 SUPERFAMILY SSF52096 25 135 2.15E-8 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS05915 36942425e270dd7906c2fa28002367ac 331 Gene3D G3DSA:3.40.50.300 1 331 4.9E-55 T 28-03-2018 A6A12_RS05915 36942425e270dd7906c2fa28002367ac 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 305 5.2E-16 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A6A12_RS05915 36942425e270dd7906c2fa28002367ac 331 Pfam PF00005 ABC transporter 24 187 1.9E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS05915 36942425e270dd7906c2fa28002367ac 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 323 2.2E-20 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A6A12_RS05915 36942425e270dd7906c2fa28002367ac 331 SUPERFAMILY SSF52540 3 268 1.6E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05915 36942425e270dd7906c2fa28002367ac 331 SMART SM00382 32 238 2.0E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS05185 c6a90eaf6928c68af2329f284ec8883f 433 PIRSF PIRSF003095 1 433 6.4E-129 T 28-03-2018 IPR005215 Trigger factor GO:0015031 A6A12_RS05185 c6a90eaf6928c68af2329f284ec8883f 433 Gene3D G3DSA:1.10.3120.10 211 389 7.2E-48 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 A6A12_RS05185 c6a90eaf6928c68af2329f284ec8883f 433 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 158 233 8.2E-12 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A6A12_RS05185 c6a90eaf6928c68af2329f284ec8883f 433 SUPERFAMILY SSF109998 248 429 3.14E-49 T 28-03-2018 IPR027304 Trigger factor/SurA domain A6A12_RS05185 c6a90eaf6928c68af2329f284ec8883f 433 SUPERFAMILY SSF102735 1 131 4.97E-42 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A6A12_RS05185 c6a90eaf6928c68af2329f284ec8883f 433 SUPERFAMILY SSF54534 89 240 1.51E-36 T 28-03-2018 A6A12_RS05185 c6a90eaf6928c68af2329f284ec8883f 433 TIGRFAM TIGR00115 tig: trigger factor 11 412 1.6E-143 T 28-03-2018 IPR005215 Trigger factor GO:0015031 A6A12_RS05185 c6a90eaf6928c68af2329f284ec8883f 433 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 263 412 1.8E-39 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 A6A12_RS05185 c6a90eaf6928c68af2329f284ec8883f 433 Hamap MF_00303 Trigger factor [tig]. 1 418 21.827 T 28-03-2018 IPR005215 Trigger factor GO:0015031 A6A12_RS05185 c6a90eaf6928c68af2329f284ec8883f 433 Gene3D G3DSA:3.30.70.1050 1 118 5.0E-37 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A6A12_RS05185 c6a90eaf6928c68af2329f284ec8883f 433 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 3.7E-43 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 A6A12_RS02040 22716bef49ef4fa69654c886fa0af8e4 253 Gene3D G3DSA:3.40.50.1360 67 242 8.4E-34 T 28-03-2018 A6A12_RS02040 22716bef49ef4fa69654c886fa0af8e4 253 SUPERFAMILY SSF46785 9 65 5.57E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS02040 22716bef49ef4fa69654c886fa0af8e4 253 Pfam PF00455 DeoR C terminal sensor domain 77 233 1.9E-45 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain A6A12_RS02040 22716bef49ef4fa69654c886fa0af8e4 253 ProSitePatterns PS00894 DeoR-type HTH domain signature. 9 43 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 A6A12_RS02040 22716bef49ef4fa69654c886fa0af8e4 253 SMART SM00420 9 61 2.3E-14 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A6A12_RS02040 22716bef49ef4fa69654c886fa0af8e4 253 SMART SM01134 73 234 5.5E-57 T 28-03-2018 A6A12_RS02040 22716bef49ef4fa69654c886fa0af8e4 253 Gene3D G3DSA:1.10.10.10 1 66 6.1E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS02040 22716bef49ef4fa69654c886fa0af8e4 253 SUPERFAMILY SSF100950 77 233 4.67E-32 T 28-03-2018 A6A12_RS02040 22716bef49ef4fa69654c886fa0af8e4 253 Pfam PF08220 DeoR-like helix-turn-helix domain 9 61 3.3E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 A6A12_RS08845 e99602fcba61d096ed4aceac88389808 173 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 155 8.0E-75 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A6A12_RS08845 e99602fcba61d096ed4aceac88389808 173 SUPERFAMILY SSF53098 3 156 6.83E-55 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS08845 e99602fcba61d096ed4aceac88389808 173 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 147 - T 28-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 A6A12_RS08845 e99602fcba61d096ed4aceac88389808 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 1.1E-42 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A6A12_RS08845 e99602fcba61d096ed4aceac88389808 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 1.1E-42 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A6A12_RS08845 e99602fcba61d096ed4aceac88389808 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 1.1E-42 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A6A12_RS08845 e99602fcba61d096ed4aceac88389808 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 1.1E-42 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A6A12_RS08845 e99602fcba61d096ed4aceac88389808 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 5 18 1.1E-42 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A6A12_RS08845 e99602fcba61d096ed4aceac88389808 173 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 2 153 47.012 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A6A12_RS08845 e99602fcba61d096ed4aceac88389808 173 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 4 150 6.7E-62 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 A6A12_RS08845 e99602fcba61d096ed4aceac88389808 173 Gene3D G3DSA:3.30.420.10 2 159 2.6E-51 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS12335 957d2656f2b16aaa658d4b9cd1e6993c 255 Pfam PF05742 Transport and Golgi organisation 2 10 195 3.4E-13 T 28-03-2018 IPR008551 Transport and Golgi organisation protein 2 A6A12_RS02610 386be3ceb1e2cc6ee466076a1b51e066 141 Gene3D G3DSA:3.30.700.10 12 141 5.5E-27 T 28-03-2018 A6A12_RS02610 386be3ceb1e2cc6ee466076a1b51e066 141 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 32 9.6E-10 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS02610 386be3ceb1e2cc6ee466076a1b51e066 141 SUPERFAMILY SSF54523 12 140 4.71E-26 T 28-03-2018 A6A12_RS02610 386be3ceb1e2cc6ee466076a1b51e066 141 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS02610 386be3ceb1e2cc6ee466076a1b51e066 141 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 31 3.1E-10 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS02610 386be3ceb1e2cc6ee466076a1b51e066 141 Pfam PF00114 Pilin (bacterial filament) 40 140 2.6E-17 T 28-03-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 A6A12_RS08370 df0250877af8ab1cc4e1ddfe461dee46 109 Pfam PF10571 Uncharacterised protein family UPF0547 5 30 7.8E-8 T 28-03-2018 IPR018886 Uncharacterised domain UPF0547 A6A12_RS09665 e21dd33b1e82fcca0e41e1128eb409a5 338 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 5 333 32.923 T 28-03-2018 IPR003770 Endolytic murein transglycosylase A6A12_RS09665 e21dd33b1e82fcca0e41e1128eb409a5 338 Gene3D G3DSA:3.30.160.60 303 337 5.3E-16 T 28-03-2018 A6A12_RS09665 e21dd33b1e82fcca0e41e1128eb409a5 338 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 7 335 3.6E-95 T 28-03-2018 IPR003770 Endolytic murein transglycosylase A6A12_RS09665 e21dd33b1e82fcca0e41e1128eb409a5 338 Gene3D G3DSA:3.30.160.60 75 109 6.9E-10 T 28-03-2018 A6A12_RS09665 e21dd33b1e82fcca0e41e1128eb409a5 338 Pfam PF02618 YceG-like family 43 328 3.3E-81 T 28-03-2018 IPR003770 Endolytic murein transglycosylase A6A12_RS01680 a65a966d7f50ffeb3987de4e83383bfd 1294 Pfam PF13116 Protein of unknown function 503 789 1.4E-94 T 28-03-2018 IPR025263 Domain of unknown function DUF3971 A6A12_RS01680 a65a966d7f50ffeb3987de4e83383bfd 1294 Pfam PF13502 AsmA-like C-terminal region 1026 1270 9.5E-56 T 28-03-2018 IPR032712 AsmA-like, C-terminal A6A12_RS01680 a65a966d7f50ffeb3987de4e83383bfd 1294 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 7 1281 0.0 T 28-03-2018 IPR011836 Conserved hypothetical protein CHP02099 A6A12_RS09820 10fa77e923a1aa4cafe2c42fb7ec3d14 255 SUPERFAMILY SSF51735 32 218 2.73E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS09820 10fa77e923a1aa4cafe2c42fb7ec3d14 255 Gene3D G3DSA:3.40.50.720 9 218 4.3E-19 T 28-03-2018 A6A12_RS09820 10fa77e923a1aa4cafe2c42fb7ec3d14 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 125 7.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09820 10fa77e923a1aa4cafe2c42fb7ec3d14 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 205 7.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09820 10fa77e923a1aa4cafe2c42fb7ec3d14 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 179 7.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09820 10fa77e923a1aa4cafe2c42fb7ec3d14 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 39 56 7.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09820 10fa77e923a1aa4cafe2c42fb7ec3d14 255 Pfam PF00106 short chain dehydrogenase 39 217 7.2E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS06270 67d75bfd9c59cdc451af2752f4d6afdd 173 Pfam PF03802 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase 7 171 1.1E-52 T 28-03-2018 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 A6A12_RS06270 67d75bfd9c59cdc451af2752f4d6afdd 173 TIGRFAM TIGR03124 citrate_citX: holo-ACP synthase CitX 7 171 1.8E-50 T 28-03-2018 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 A6A12_RS01365 9f6bcf3ac72656f8e23757b8187751e6 156 PIRSF PIRSF002122 3 156 7.2E-62 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 A6A12_RS01365 9f6bcf3ac72656f8e23757b8187751e6 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 3.4E-70 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A6A12_RS01365 9f6bcf3ac72656f8e23757b8187751e6 156 SUPERFAMILY SSF47973 6 149 8.11E-59 T 28-03-2018 IPR023798 Ribosomal protein S7 domain A6A12_RS01365 9f6bcf3ac72656f8e23757b8187751e6 156 Gene3D G3DSA:1.10.455.10 6 156 3.8E-62 T 28-03-2018 IPR023798 Ribosomal protein S7 domain A6A12_RS01365 9f6bcf3ac72656f8e23757b8187751e6 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS01365 9f6bcf3ac72656f8e23757b8187751e6 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.508 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 A6A12_RS01365 9f6bcf3ac72656f8e23757b8187751e6 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.3E-64 T 28-03-2018 IPR023798 Ribosomal protein S7 domain A6A12_RS08595 796933a00422ab62b2a894c8d6897054 223 SUPERFAMILY SSF47413 2 59 2.69E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS08595 796933a00422ab62b2a894c8d6897054 223 Gene3D G3DSA:1.10.260.40 2 66 9.5E-13 T 28-03-2018 A6A12_RS08595 796933a00422ab62b2a894c8d6897054 223 Pfam PF00717 Peptidase S24-like 135 208 3.7E-15 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A6A12_RS08595 796933a00422ab62b2a894c8d6897054 223 SMART SM00530 8 63 2.0E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A6A12_RS08595 796933a00422ab62b2a894c8d6897054 223 Gene3D G3DSA:2.10.109.10 96 222 6.5E-19 T 28-03-2018 A6A12_RS08595 796933a00422ab62b2a894c8d6897054 223 SUPERFAMILY SSF51306 128 218 5.58E-27 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A6A12_RS08595 796933a00422ab62b2a894c8d6897054 223 Pfam PF01381 Helix-turn-helix 10 57 1.7E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A6A12_RS06115 111f8c68cc2ed68c4b544e649d5b0ef5 817 Pfam PF02687 FtsX-like permease family 715 809 8.1E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A6A12_RS13210 55d6d2396268c8a59e37ca6c2ec6bb4b 180 SUPERFAMILY SSF52540 3 150 1.69E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13210 55d6d2396268c8a59e37ca6c2ec6bb4b 180 Gene3D G3DSA:3.40.50.300 1 171 4.0E-5 T 28-03-2018 A6A12_RS00290 6090530c48742cb10f4260a03975b960 379 SUPERFAMILY SSF56059 92 295 3.54E-54 T 28-03-2018 A6A12_RS00290 6090530c48742cb10f4260a03975b960 379 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 2 346 36.675 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A6A12_RS00290 6090530c48742cb10f4260a03975b960 379 Pfam PF02222 ATP-grasp domain 101 274 1.5E-48 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A6A12_RS00290 6090530c48742cb10f4260a03975b960 379 SUPERFAMILY SSF52440 1 88 4.6E-16 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A6A12_RS00290 6090530c48742cb10f4260a03975b960 379 Gene3D G3DSA:3.30.470.20 177 362 1.0E-31 T 28-03-2018 A6A12_RS00290 6090530c48742cb10f4260a03975b960 379 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 2 350 2.6E-105 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 A6A12_RS00290 6090530c48742cb10f4260a03975b960 379 SUPERFAMILY SSF51246 298 371 2.28E-18 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A6A12_RS00290 6090530c48742cb10f4260a03975b960 379 Gene3D G3DSA:3.40.50.20 1 81 1.1E-16 T 28-03-2018 A6A12_RS00290 6090530c48742cb10f4260a03975b960 379 Gene3D G3DSA:3.30.1490.20 107 176 3.7E-13 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A6A12_RS06340 220042e265e26be28a39ac507cc1fc44 324 Pfam PF13407 Periplasmic binding protein domain 26 296 1.5E-60 T 28-03-2018 IPR025997 Periplasmic binding protein A6A12_RS06340 220042e265e26be28a39ac507cc1fc44 324 Gene3D G3DSA:3.40.50.2300 24 134 2.0E-14 T 28-03-2018 A6A12_RS06340 220042e265e26be28a39ac507cc1fc44 324 SUPERFAMILY SSF53822 23 323 3.26E-79 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A6A12_RS06340 220042e265e26be28a39ac507cc1fc44 324 Gene3D G3DSA:3.40.50.2300 135 324 8.4E-37 T 28-03-2018 A6A12_RS04400 1dc6b849abd48b4cf65221009fe7ff3f 506 Gene3D G3DSA:3.60.110.10 206 483 3.5E-41 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A6A12_RS04400 1dc6b849abd48b4cf65221009fe7ff3f 506 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 8 490 23.4 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 A6A12_RS04400 1dc6b849abd48b4cf65221009fe7ff3f 506 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 61 453 2.3E-97 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 A6A12_RS04400 1dc6b849abd48b4cf65221009fe7ff3f 506 SUPERFAMILY SSF56317 215 485 4.19E-41 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A6A12_RS04400 1dc6b849abd48b4cf65221009fe7ff3f 506 Pfam PF00795 Carbon-nitrogen hydrolase 221 473 5.8E-39 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A6A12_RS12420 6241bb7b1b6fcd6e232ec9abfa8fbd5c 166 SUPERFAMILY SSF54768 8 75 6.91E-24 T 28-03-2018 A6A12_RS12420 6241bb7b1b6fcd6e232ec9abfa8fbd5c 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 34.429 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A6A12_RS12420 6241bb7b1b6fcd6e232ec9abfa8fbd5c 166 Gene3D G3DSA:3.30.160.20 10 72 7.9E-28 T 28-03-2018 A6A12_RS12420 6241bb7b1b6fcd6e232ec9abfa8fbd5c 166 Gene3D G3DSA:3.30.230.10 76 166 6.7E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A6A12_RS12420 6241bb7b1b6fcd6e232ec9abfa8fbd5c 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 162 7.6E-68 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 A6A12_RS12420 6241bb7b1b6fcd6e232ec9abfa8fbd5c 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 74 2.7E-29 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 A6A12_RS12420 6241bb7b1b6fcd6e232ec9abfa8fbd5c 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site A6A12_RS12420 6241bb7b1b6fcd6e232ec9abfa8fbd5c 166 SUPERFAMILY SSF54211 79 158 2.53E-26 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS12420 6241bb7b1b6fcd6e232ec9abfa8fbd5c 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 7.3E-29 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 A6A12_RS07510 b33cf5b4d822b91d931ac94107f03be3 460 Pfam PF06537 Di-haem oxidoreductase, putative peroxidase 18 460 7.6E-143 T 28-03-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase A6A12_RS07510 b33cf5b4d822b91d931ac94107f03be3 460 Gene3D G3DSA:1.10.760.10 303 460 1.4E-26 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS07510 b33cf5b4d822b91d931ac94107f03be3 460 PIRSF PIRSF028099 4 460 2.6E-186 T 28-03-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase A6A12_RS07510 b33cf5b4d822b91d931ac94107f03be3 460 Gene3D G3DSA:1.10.760.10 59 302 0.0015 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS07510 b33cf5b4d822b91d931ac94107f03be3 460 SUPERFAMILY SSF46626 318 460 1.02E-24 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS04520 b752db7b752f0094ecbfa64819bce684 288 SUPERFAMILY SSF46894 6 109 8.22E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS04520 b752db7b752f0094ecbfa64819bce684 288 SMART SM00862 30 107 4.4E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS04520 b752db7b752f0094ecbfa64819bce684 288 Pfam PF00486 Transcriptional regulatory protein, C terminal 31 107 5.6E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS04520 b752db7b752f0094ecbfa64819bce684 288 Gene3D G3DSA:1.10.10.10 5 114 4.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS06590 8004815c2024ce461105abac029c9916 209 Pfam PF04352 ProQ/FINO family 8 115 2.6E-43 T 28-03-2018 IPR016103 ProQ/FinO domain A6A12_RS06590 8004815c2024ce461105abac029c9916 209 Pfam PF17516 ProQ C-terminal domain 160 208 4.1E-20 T 28-03-2018 IPR035236 RNA chaperone ProQ, C-terminal A6A12_RS06590 8004815c2024ce461105abac029c9916 209 SUPERFAMILY SSF48657 5 117 3.53E-39 T 28-03-2018 IPR016103 ProQ/FinO domain A6A12_RS06590 8004815c2024ce461105abac029c9916 209 Hamap MF_00749 RNA chaperone ProQ [proQ]. 3 209 30.175 T 28-03-2018 IPR023529 RNA chaperone ProQ GO:0003723|GO:0010608|GO:0033592|GO:0034057 A6A12_RS06590 8004815c2024ce461105abac029c9916 209 SMART SM00945 5 119 9.1E-62 T 28-03-2018 IPR016103 ProQ/FinO domain A6A12_RS06590 8004815c2024ce461105abac029c9916 209 Gene3D G3DSA:1.10.1710.10 1 119 1.5E-40 T 28-03-2018 IPR016103 ProQ/FinO domain A6A12_RS12875 cbb3e9e3c6c826610d72af4a9c05db3d 173 TIGRFAM TIGR02998 RraA_entero: regulator of ribonuclease activity A 1 160 7.8E-84 T 28-03-2018 IPR014339 Regulator of ribonuclease activity A, gammaproteobacteria GO:0008428|GO:0051252 A6A12_RS12875 cbb3e9e3c6c826610d72af4a9c05db3d 173 Pfam PF03737 Aldolase/RraA 6 152 7.4E-39 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein A6A12_RS12875 cbb3e9e3c6c826610d72af4a9c05db3d 173 Hamap MF_00471 Regulator of ribonuclease activity A [rraA]. 1 161 48.123 T 28-03-2018 IPR014339 Regulator of ribonuclease activity A, gammaproteobacteria GO:0008428|GO:0051252 A6A12_RS12875 cbb3e9e3c6c826610d72af4a9c05db3d 173 TIGRFAM TIGR01935 NOT-MenG: RraA family 5 154 4.1E-68 T 28-03-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 A6A12_RS12875 cbb3e9e3c6c826610d72af4a9c05db3d 173 Gene3D G3DSA:3.50.30.40 1 162 3.8E-40 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein A6A12_RS12875 cbb3e9e3c6c826610d72af4a9c05db3d 173 SUPERFAMILY SSF89562 2 158 5.76E-47 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein A6A12_RS11610 8d7bbb0539d27af5729f8ed0d4f64070 245 Gene3D G3DSA:1.20.5.100 214 245 6.0E-14 T 28-03-2018 A6A12_RS11610 8d7bbb0539d27af5729f8ed0d4f64070 245 Gene3D G3DSA:1.10.760.10 24 210 2.2E-55 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS11610 8d7bbb0539d27af5729f8ed0d4f64070 245 Pfam PF02167 Cytochrome C1 family 34 244 2.3E-18 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 A6A12_RS11610 8d7bbb0539d27af5729f8ed0d4f64070 245 SUPERFAMILY SSF46626 16 209 1.09E-48 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS04010 9417f627fcfc62f79245eaa67dd525ac 41 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 3.9E-8 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS04010 9417f627fcfc62f79245eaa67dd525ac 41 ProSitePatterns PS00828 Ribosomal protein L36 signature. 14 40 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS04010 9417f627fcfc62f79245eaa67dd525ac 41 SUPERFAMILY SSF57840 1 40 7.72E-14 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS04010 9417f627fcfc62f79245eaa67dd525ac 41 Pfam PF00444 Ribosomal protein L36 1 40 4.0E-17 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS04010 9417f627fcfc62f79245eaa67dd525ac 41 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 41 16.252 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS05890 464f06b6401fc4e258dd0ee5c208899f 578 SUPERFAMILY SSF51445 191 524 3.71E-75 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A6A12_RS05890 464f06b6401fc4e258dd0ee5c208899f 578 Gene3D G3DSA:3.20.20.70 183 499 2.5E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS05890 464f06b6401fc4e258dd0ee5c208899f 578 Pfam PF02065 Melibiase 161 350 2.7E-21 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 A6A12_RS13540 0f71f7e951351464f9e0756d81bf49f1 325 TIGRFAM TIGR02208 lipid_A_msbB: lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 14 316 6.9E-118 T 28-03-2018 IPR011921 Lipid A biosynthesis myristoyltransferase GO:0009103|GO:0009276|GO:0016021|GO:0016747 KEGG: 00540+2.3.1.243|KEGG: 00600+2.3.1.24 A6A12_RS13540 0f71f7e951351464f9e0756d81bf49f1 325 PIRSF PIRSF026649 13 316 5.0E-87 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 A6A12_RS13540 0f71f7e951351464f9e0756d81bf49f1 325 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 15 308 6.6E-76 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 A6A12_RS13540 0f71f7e951351464f9e0756d81bf49f1 325 Hamap MF_01944 Lipid A biosynthesis myristoyltransferase [lpxM]. 7 313 49.432 T 28-03-2018 IPR011921 Lipid A biosynthesis myristoyltransferase GO:0009103|GO:0009276|GO:0016021|GO:0016747 KEGG: 00540+2.3.1.243|KEGG: 00600+2.3.1.24 A6A12_RS07485 4d5ddd7a6bf6ce09fa70ada20a8c85cb 218 SMART SM00849 14 195 4.3E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS07485 4d5ddd7a6bf6ce09fa70ada20a8c85cb 218 Pfam PF00753 Metallo-beta-lactamase superfamily 14 195 4.4E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS07485 4d5ddd7a6bf6ce09fa70ada20a8c85cb 218 Gene3D G3DSA:3.60.15.10 3 215 2.5E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS07485 4d5ddd7a6bf6ce09fa70ada20a8c85cb 218 SUPERFAMILY SSF56281 5 211 3.93E-54 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS05665 b1deee2db7747c1837c36d1f530bc6c5 257 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 256 7.2E-113 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A6A12_RS05665 b1deee2db7747c1837c36d1f530bc6c5 257 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 256 43.997 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 A6A12_RS05665 b1deee2db7747c1837c36d1f530bc6c5 257 Pfam PF00977 Histidine biosynthesis protein 5 239 2.5E-78 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 A6A12_RS05665 b1deee2db7747c1837c36d1f530bc6c5 257 Gene3D G3DSA:3.20.20.70 4 252 3.9E-59 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS05665 b1deee2db7747c1837c36d1f530bc6c5 257 SUPERFAMILY SSF51366 1 256 4.63E-73 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A6A12_RS11390 ac0659efda5fc1ed9b41912796eeb500 238 Gene3D G3DSA:1.10.10.10 131 238 2.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS11390 ac0659efda5fc1ed9b41912796eeb500 238 SUPERFAMILY SSF46894 137 233 3.97E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS11390 ac0659efda5fc1ed9b41912796eeb500 238 SMART SM00448 4 114 1.7E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS11390 ac0659efda5fc1ed9b41912796eeb500 238 SUPERFAMILY SSF52172 2 130 4.27E-36 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS11390 ac0659efda5fc1ed9b41912796eeb500 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 232 2.9E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS11390 ac0659efda5fc1ed9b41912796eeb500 238 Pfam PF00072 Response regulator receiver domain 6 113 5.2E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS11390 ac0659efda5fc1ed9b41912796eeb500 238 Gene3D G3DSA:3.40.50.2300 1 130 8.7E-33 T 28-03-2018 A6A12_RS11390 ac0659efda5fc1ed9b41912796eeb500 238 SMART SM00862 156 232 2.4E-14 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS09155 41106db7c69b99b59b3e683ada541076 218 SUPERFAMILY SSF103642 198 217 1.8E-7 T 28-03-2018 A6A12_RS09155 41106db7c69b99b59b3e683ada541076 218 Gene3D G3DSA:3.10.450.50 62 218 1.1E-13 T 28-03-2018 A6A12_RS09155 41106db7c69b99b59b3e683ada541076 218 Pfam PF02810 SEC-C motif 200 218 1.3E-9 T 28-03-2018 IPR004027 SEC-C motif A6A12_RS09155 41106db7c69b99b59b3e683ada541076 218 Pfam PF03695 Uncharacterised protein family (UPF0149) 29 173 1.2E-5 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 A6A12_RS14140 c5ff854ff7d07bbc3968caf3da908d8f 330 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 30 323 1.2E-72 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain A6A12_RS14140 c5ff854ff7d07bbc3968caf3da908d8f 330 Gene3D G3DSA:3.40.50.2300 28 153 2.4E-11 T 28-03-2018 A6A12_RS14140 c5ff854ff7d07bbc3968caf3da908d8f 330 PIRSF PIRSF002816 1 330 1.8E-146 T 28-03-2018 IPR026266 L-arabinose-binding periplasmic protein GO:0042882 A6A12_RS14140 c5ff854ff7d07bbc3968caf3da908d8f 330 Gene3D G3DSA:3.40.50.2300 154 279 1.2E-12 T 28-03-2018 A6A12_RS14140 c5ff854ff7d07bbc3968caf3da908d8f 330 SUPERFAMILY SSF53822 30 327 3.53E-66 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A6A12_RS11065 d714346381540e51c6ed0f0181acf187 255 Hamap MF_00427 Na(+)-translocating NADH-quinone reductase subunit C [nqrC]. 6 252 35.771 T 28-03-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 A6A12_RS11065 d714346381540e51c6ed0f0181acf187 255 TIGRFAM TIGR01938 nqrC: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit 5 248 1.8E-94 T 28-03-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 A6A12_RS11065 d714346381540e51c6ed0f0181acf187 255 Pfam PF04205 FMN-binding domain 142 237 1.3E-15 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 A6A12_RS11065 d714346381540e51c6ed0f0181acf187 255 PIRSF PIRSF009437 1 255 2.7E-105 T 28-03-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 A6A12_RS11065 d714346381540e51c6ed0f0181acf187 255 SMART SM00900 142 240 1.2E-33 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 A6A12_RS10820 b903bffbdfc0ec7f0c550561092a73d9 103 PRINTS PR00605 Class IC cytochrome C signature 32 43 8.5E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 A6A12_RS10820 b903bffbdfc0ec7f0c550561092a73d9 103 PRINTS PR00605 Class IC cytochrome C signature 77 99 8.5E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 A6A12_RS10820 b903bffbdfc0ec7f0c550561092a73d9 103 Pfam PF00034 Cytochrome c 32 103 1.7E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS10820 b903bffbdfc0ec7f0c550561092a73d9 103 Gene3D G3DSA:1.10.760.10 12 102 1.1E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS10820 b903bffbdfc0ec7f0c550561092a73d9 103 SUPERFAMILY SSF46626 14 102 6.06E-22 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS13935 f5a459fbd1dee876304c699eb00af2c8 308 SUPERFAMILY SSF110997 67 139 3.14E-6 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A6A12_RS13935 f5a459fbd1dee876304c699eb00af2c8 308 Pfam PF05036 Sporulation related domain 68 133 1.4E-5 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A6A12_RS13390 6da5331e04c261d6249cb46fd4b60ae8 446 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS13390 6da5331e04c261d6249cb46fd4b60ae8 446 Pfam PF14524 Wzt C-terminal domain 295 425 5.6E-31 T 28-03-2018 IPR029439 Wzt, C-terminal A6A12_RS13390 6da5331e04c261d6249cb46fd4b60ae8 446 SMART SM00382 52 226 9.8E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS13390 6da5331e04c261d6249cb46fd4b60ae8 446 Pfam PF00005 ABC transporter 43 175 5.4E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS13390 6da5331e04c261d6249cb46fd4b60ae8 446 Gene3D G3DSA:2.70.50.60 297 431 1.0E-24 T 28-03-2018 A6A12_RS13390 6da5331e04c261d6249cb46fd4b60ae8 446 SUPERFAMILY SSF52540 35 241 1.08E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13390 6da5331e04c261d6249cb46fd4b60ae8 446 Gene3D G3DSA:3.40.50.300 2 296 1.3E-51 T 28-03-2018 A6A12_RS08145 0068d50445cf340370ec3ba197a580c3 160 SUPERFAMILY SSF55729 1 159 1.49E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS08145 0068d50445cf340370ec3ba197a580c3 160 Pfam PF00583 Acetyltransferase (GNAT) family 39 137 2.9E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A6A12_RS08145 0068d50445cf340370ec3ba197a580c3 160 Gene3D G3DSA:3.40.630.30 1 160 2.1E-27 T 28-03-2018 A6A12_RS06200 723a3925ce85201c401494077e56b496 548 SUPERFAMILY SSF58104 240 548 1.06E-72 T 28-03-2018 A6A12_RS06200 723a3925ce85201c401494077e56b496 548 Gene3D G3DSA:1.10.287.950 332 548 9.3E-53 T 28-03-2018 A6A12_RS06200 723a3925ce85201c401494077e56b496 548 Gene3D G3DSA:1.20.120.30 24 192 8.6E-19 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain A6A12_RS06200 723a3925ce85201c401494077e56b496 548 SMART SM00283 286 547 2.1E-86 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS06200 723a3925ce85201c401494077e56b496 548 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 330 515 2.8E-41 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS06200 723a3925ce85201c401494077e56b496 548 Gene3D G3DSA:1.10.287.1060 249 331 0.015 T 28-03-2018 A6A12_RS06200 723a3925ce85201c401494077e56b496 548 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 191 4.4E-20 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain A6A12_RS09510 feb9b1fcbad35b6919d150a2ba1bc3fc 198 SUPERFAMILY SSF48498 83 195 7.19E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A6A12_RS09510 feb9b1fcbad35b6919d150a2ba1bc3fc 198 Pfam PF13305 WHG domain 93 172 2.0E-10 T 28-03-2018 IPR025996 WHG domain A6A12_RS09510 feb9b1fcbad35b6919d150a2ba1bc3fc 198 SUPERFAMILY SSF46689 2 75 1.7E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS09510 feb9b1fcbad35b6919d150a2ba1bc3fc 198 Gene3D G3DSA:1.10.10.60 2 64 6.1E-9 T 28-03-2018 A6A12_RS09510 feb9b1fcbad35b6919d150a2ba1bc3fc 198 Gene3D G3DSA:1.10.357.10 65 197 3.2E-17 T 28-03-2018 A6A12_RS03805 ad828af42765278d8ee28b14e376bc08 157 TIGRFAM TIGR00608 radc: DNA repair protein RadC 23 157 5.5E-43 T 28-03-2018 IPR001405 RadC protein A6A12_RS03805 ad828af42765278d8ee28b14e376bc08 157 SUPERFAMILY SSF102712 52 126 4.58E-6 T 28-03-2018 A6A12_RS03805 ad828af42765278d8ee28b14e376bc08 157 Gene3D G3DSA:3.40.140.10 33 157 5.4E-45 T 28-03-2018 A6A12_RS03805 ad828af42765278d8ee28b14e376bc08 157 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 107 112 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site A6A12_RS03805 ad828af42765278d8ee28b14e376bc08 157 Pfam PF04002 RadC-like JAB domain 38 155 2.8E-43 T 28-03-2018 IPR025657 RadC-like JAB domain A6A12_RS10955 9e50961182b1102e70f314d1573ce0c5 218 Pfam PF00677 Lumazine binding domain 3 87 1.5E-21 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A6A12_RS10955 9e50961182b1102e70f314d1573ce0c5 218 Pfam PF00677 Lumazine binding domain 100 184 4.6E-23 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A6A12_RS10955 9e50961182b1102e70f314d1573ce0c5 218 SUPERFAMILY SSF63380 1 89 2.13E-25 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A6A12_RS10955 9e50961182b1102e70f314d1573ce0c5 218 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 201 1.2E-65 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A6A12_RS10955 9e50961182b1102e70f314d1573ce0c5 218 Gene3D G3DSA:2.40.30.20 94 191 2.1E-32 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS10955 9e50961182b1102e70f314d1573ce0c5 218 PIRSF PIRSF000498 1 212 8.0E-80 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A6A12_RS10955 9e50961182b1102e70f314d1573ce0c5 218 SUPERFAMILY SSF63380 93 198 4.17E-32 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 A6A12_RS10955 9e50961182b1102e70f314d1573ce0c5 218 Gene3D G3DSA:2.40.30.20 1 89 3.8E-26 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS03635 b113add18912f835ddd5bde40adcf131 106 SUPERFAMILY SSF143410 1 104 1.44E-29 T 28-03-2018 IPR023389 DOPA-like domain A6A12_RS03635 b113add18912f835ddd5bde40adcf131 106 PIRSF PIRSF028139 1 106 2.2E-37 T 28-03-2018 IPR014980 Dopa 4,5-dioxygenase A6A12_RS03635 b113add18912f835ddd5bde40adcf131 106 Gene3D G3DSA:3.30.70.1240 1 105 2.3E-27 T 28-03-2018 IPR023389 DOPA-like domain A6A12_RS03635 b113add18912f835ddd5bde40adcf131 106 Pfam PF08883 Dopa 4,5-dioxygenase family 2 102 2.3E-24 T 28-03-2018 IPR014980 Dopa 4,5-dioxygenase A6A12_RS00660 22613ae68da65231eb8b7bd6791c0e34 193 SUPERFAMILY SSF53041 1 135 5.49E-46 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A6A12_RS00660 22613ae68da65231eb8b7bd6791c0e34 193 SUPERFAMILY SSF46689 138 182 5.38E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS00660 22613ae68da65231eb8b7bd6791c0e34 193 Gene3D G3DSA:1.20.5.40 105 123 2.0E-19 T 28-03-2018 A6A12_RS00660 22613ae68da65231eb8b7bd6791c0e34 193 SMART SM00857 2 136 1.1E-61 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A6A12_RS00660 22613ae68da65231eb8b7bd6791c0e34 193 Gene3D G3DSA:1.10.10.60 124 187 3.6E-6 T 28-03-2018 A6A12_RS00660 22613ae68da65231eb8b7bd6791c0e34 193 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A6A12_RS00660 22613ae68da65231eb8b7bd6791c0e34 193 Gene3D G3DSA:3.40.50.1390 1 104 9.5E-34 T 28-03-2018 A6A12_RS00660 22613ae68da65231eb8b7bd6791c0e34 193 Pfam PF00239 Resolvase, N terminal domain 3 135 3.2E-46 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A6A12_RS00660 22613ae68da65231eb8b7bd6791c0e34 193 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A6A12_RS03370 8a73c289e2f96f80a0c6b84f43853db0 84 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A6A12_RS03370 8a73c289e2f96f80a0c6b84f43853db0 84 SUPERFAMILY SSF54862 5 71 9.07E-17 T 28-03-2018 A6A12_RS03370 8a73c289e2f96f80a0c6b84f43853db0 84 Gene3D G3DSA:3.30.70.20 2 83 5.5E-15 T 28-03-2018 A6A12_RS03370 8a73c289e2f96f80a0c6b84f43853db0 84 Pfam PF00037 4Fe-4S binding domain 5 25 1.1E-5 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A6A12_RS05820 d9d06807cc98b3696fce5559dbc73a4d 247 Hamap MF_01589 Carboxy-S-adenosyl-L-methionine synthase [cmoA]. 8 247 42.962 T 28-03-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 A6A12_RS05820 d9d06807cc98b3696fce5559dbc73a4d 247 TIGRFAM TIGR00740 TIGR00740: tRNA (cmo5U34)-methyltransferase 9 247 8.0E-119 T 28-03-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 A6A12_RS05820 d9d06807cc98b3696fce5559dbc73a4d 247 SUPERFAMILY SSF53335 25 247 5.27E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS05820 d9d06807cc98b3696fce5559dbc73a4d 247 PIRSF PIRSF006325 6 247 1.1E-125 T 28-03-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 A6A12_RS05820 d9d06807cc98b3696fce5559dbc73a4d 247 Gene3D G3DSA:3.40.50.150 23 247 1.2E-39 T 28-03-2018 A6A12_RS05820 d9d06807cc98b3696fce5559dbc73a4d 247 Pfam PF13649 Methyltransferase domain 65 163 2.1E-13 T 28-03-2018 A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 3 465 3.8E-196 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 SUPERFAMILY SSF52374 3 301 5.09E-109 T 28-03-2018 A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 Gene3D G3DSA:1.10.10.350 369 475 6.2E-28 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 2 464 32.703 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 Gene3D G3DSA:3.40.50.620 125 234 2.7E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 Gene3D G3DSA:1.10.8.70 320 364 2.2E-11 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 SUPERFAMILY SSF48163 302 464 9.02E-50 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 PRINTS PR00987 Glutamyl-tRNA synthetase signature 182 192 1.4E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 1.4E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 1.4E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 1.4E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 PRINTS PR00987 Glutamyl-tRNA synthetase signature 198 206 1.4E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 308 1.9E-114 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 Gene3D G3DSA:3.40.50.620 3 122 8.1E-39 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS10710 21bb5d45723cbccfb150d154e77225d0 475 Gene3D G3DSA:1.10.1160.10 235 316 1.1E-33 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 A6A12_RS00275 9506b48e59ebf6318a72a0f28c0cfd0f 369 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 74 286 3.2E-77 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 A6A12_RS00275 9506b48e59ebf6318a72a0f28c0cfd0f 369 Gene3D G3DSA:1.10.10.10 291 365 6.6E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS00275 9506b48e59ebf6318a72a0f28c0cfd0f 369 Gene3D G3DSA:3.40.50.450 113 262 1.2E-41 T 28-03-2018 A6A12_RS00275 9506b48e59ebf6318a72a0f28c0cfd0f 369 SUPERFAMILY SSF102405 86 287 1.68E-40 T 28-03-2018 A6A12_RS00275 9506b48e59ebf6318a72a0f28c0cfd0f 369 Pfam PF02481 DNA recombination-mediator protein A 75 278 9.4E-79 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 A6A12_RS11670 c7d873f9ba2d44c0f857f2a95f89f04f 198 Gene3D G3DSA:3.40.50.1820 8 197 4.0E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS11670 c7d873f9ba2d44c0f857f2a95f89f04f 198 SUPERFAMILY SSF53474 6 197 1.11E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS11670 c7d873f9ba2d44c0f857f2a95f89f04f 198 Pfam PF05728 Uncharacterised protein family (UPF0227) 11 196 2.7E-65 T 28-03-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA A6A12_RS05600 42d8c90a46633cca380e6347761141a9 456 Gene3D G3DSA:1.10.275.10 1 117 5.9E-43 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal A6A12_RS05600 42d8c90a46633cca380e6347761141a9 456 ProSitePatterns PS00163 Fumarate lyases signature. 295 304 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A6A12_RS05600 42d8c90a46633cca380e6347761141a9 456 Gene3D G3DSA:1.20.200.10 118 391 4.3E-84 T 28-03-2018 A6A12_RS05600 42d8c90a46633cca380e6347761141a9 456 SUPERFAMILY SSF48557 4 448 1.13E-108 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 A6A12_RS05600 42d8c90a46633cca380e6347761141a9 456 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 456 2.5E-149 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A6A12_RS05600 42d8c90a46633cca380e6347761141a9 456 Pfam PF00206 Lyase 14 313 4.9E-72 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal A6A12_RS05600 42d8c90a46633cca380e6347761141a9 456 Pfam PF08328 Adenylosuccinate lyase C-terminal 332 446 1.0E-51 T 28-03-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 A6A12_RS05600 42d8c90a46633cca380e6347761141a9 456 PRINTS PR00149 Fumarate lyase superfamily signature 163 181 5.2E-19 T 28-03-2018 IPR000362 Fumarate lyase family A6A12_RS05600 42d8c90a46633cca380e6347761141a9 456 PRINTS PR00149 Fumarate lyase superfamily signature 252 279 5.2E-19 T 28-03-2018 IPR000362 Fumarate lyase family A6A12_RS05600 42d8c90a46633cca380e6347761141a9 456 PRINTS PR00149 Fumarate lyase superfamily signature 295 311 5.2E-19 T 28-03-2018 IPR000362 Fumarate lyase family A6A12_RS05600 42d8c90a46633cca380e6347761141a9 456 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 5.2E-19 T 28-03-2018 IPR000362 Fumarate lyase family A6A12_RS05600 42d8c90a46633cca380e6347761141a9 456 Gene3D G3DSA:1.10.40.30 392 446 1.1E-31 T 28-03-2018 A6A12_RS07760 d64431aea3e87d79942b1718e3eef2a8 438 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 18 437 7.3E-108 T 28-03-2018 IPR010263 Type VI secretion protein, VC_A0114 A6A12_RS07760 d64431aea3e87d79942b1718e3eef2a8 438 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 4 438 1.5E-97 T 28-03-2018 IPR010263 Type VI secretion protein, VC_A0114 A6A12_RS06365 f157fa1bbc5c74c68f9a31ca2b730f5c 122 Gene3D G3DSA:1.10.3830.10 7 119 9.1E-41 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 A6A12_RS06365 f157fa1bbc5c74c68f9a31ca2b730f5c 122 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 70 81 - T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 A6A12_RS06365 f157fa1bbc5c74c68f9a31ca2b730f5c 122 Pfam PF01219 Prokaryotic diacylglycerol kinase 16 117 2.6E-34 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 A6A12_RS06515 7bbf3861161866a8f2f79f16c0e8acfc 401 Gene3D G3DSA:1.10.3720.10 85 188 4.7E-14 T 28-03-2018 A6A12_RS06515 7bbf3861161866a8f2f79f16c0e8acfc 401 Gene3D G3DSA:1.10.3720.10 189 397 1.6E-34 T 28-03-2018 A6A12_RS06515 7bbf3861161866a8f2f79f16c0e8acfc 401 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 92 155 9.0E-16 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A6A12_RS06515 7bbf3861161866a8f2f79f16c0e8acfc 401 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 396 5.5E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS06515 7bbf3861161866a8f2f79f16c0e8acfc 401 SUPERFAMILY SSF161098 91 159 2.7E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS06515 7bbf3861161866a8f2f79f16c0e8acfc 401 SUPERFAMILY SSF161098 264 382 2.7E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS00710 fe23a8c37d3d0863ff5730032e6d7d41 69 Pfam PF01381 Helix-turn-helix 13 67 2.3E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A6A12_RS00710 fe23a8c37d3d0863ff5730032e6d7d41 69 SMART SM00530 12 67 3.1E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A6A12_RS00710 fe23a8c37d3d0863ff5730032e6d7d41 69 Gene3D G3DSA:1.10.260.40 1 69 3.9E-19 T 28-03-2018 A6A12_RS00710 fe23a8c37d3d0863ff5730032e6d7d41 69 SUPERFAMILY SSF47413 6 68 3.38E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS07240 5242aa65eeceb2ce1baf0721d10614e5 334 Gene3D G3DSA:3.40.50.2300 55 175 5.5E-30 T 28-03-2018 A6A12_RS07240 5242aa65eeceb2ce1baf0721d10614e5 334 Gene3D G3DSA:3.40.50.2300 176 313 1.2E-41 T 28-03-2018 A6A12_RS07240 5242aa65eeceb2ce1baf0721d10614e5 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 7.8E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS07240 5242aa65eeceb2ce1baf0721d10614e5 334 SUPERFAMILY SSF47413 1 57 6.83E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS07240 5242aa65eeceb2ce1baf0721d10614e5 334 SUPERFAMILY SSF53822 61 333 2.95E-68 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A6A12_RS07240 5242aa65eeceb2ce1baf0721d10614e5 334 Gene3D G3DSA:1.10.10.60 1 15 0.019 T 28-03-2018 A6A12_RS07240 5242aa65eeceb2ce1baf0721d10614e5 334 Pfam PF13377 Periplasmic binding protein-like domain 170 331 2.5E-35 T 28-03-2018 A6A12_RS07240 5242aa65eeceb2ce1baf0721d10614e5 334 SMART SM00354 1 71 1.9E-32 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS07240 5242aa65eeceb2ce1baf0721d10614e5 334 Gene3D G3DSA:1.10.260.40 16 54 9.5E-21 T 28-03-2018 A6A12_RS07240 5242aa65eeceb2ce1baf0721d10614e5 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 9.2E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS07240 5242aa65eeceb2ce1baf0721d10614e5 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 9.2E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS02350 831b0ef914f0bf44a5135666830f63d2 338 Gene3D G3DSA:3.30.420.40 145 289 8.6E-18 T 28-03-2018 A6A12_RS02350 831b0ef914f0bf44a5135666830f63d2 338 SUPERFAMILY SSF53067 3 123 1.94E-30 T 28-03-2018 A6A12_RS02350 831b0ef914f0bf44a5135666830f63d2 338 Gene3D G3DSA:3.30.420.40 1 144 2.6E-39 T 28-03-2018 A6A12_RS02350 831b0ef914f0bf44a5135666830f63d2 338 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 331 62.766 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A6A12_RS02350 831b0ef914f0bf44a5135666830f63d2 338 Pfam PF00814 Glycoprotease family 24 307 3.2E-103 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A6A12_RS02350 831b0ef914f0bf44a5135666830f63d2 338 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 5 306 1.4E-123 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A6A12_RS02350 831b0ef914f0bf44a5135666830f63d2 338 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 313 4.4E-134 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A6A12_RS02350 831b0ef914f0bf44a5135666830f63d2 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.6E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A6A12_RS02350 831b0ef914f0bf44a5135666830f63d2 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 1.6E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A6A12_RS02350 831b0ef914f0bf44a5135666830f63d2 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 263 272 1.6E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A6A12_RS02350 831b0ef914f0bf44a5135666830f63d2 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 1.6E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A6A12_RS02350 831b0ef914f0bf44a5135666830f63d2 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 1.6E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A6A12_RS02350 831b0ef914f0bf44a5135666830f63d2 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 1.6E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 A6A12_RS02350 831b0ef914f0bf44a5135666830f63d2 338 SUPERFAMILY SSF53067 101 309 2.37E-44 T 28-03-2018 A6A12_RS02350 831b0ef914f0bf44a5135666830f63d2 338 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 A6A12_RS02765 9a8513c614e5ce3805b210c8b89358ea 381 Gene3D G3DSA:1.10.10.60 304 358 2.2E-8 T 28-03-2018 A6A12_RS02765 9a8513c614e5ce3805b210c8b89358ea 381 Pfam PF05651 Putative sugar diacid recognition 4 136 5.5E-52 T 28-03-2018 IPR008599 Putative sugar diacid recognition A6A12_RS02765 9a8513c614e5ce3805b210c8b89358ea 381 Pfam PF13556 PucR C-terminal helix-turn-helix domain 321 377 6.5E-20 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain A6A12_RS14060 3423ef60d6a0c4fe695eef21d557233a 348 SUPERFAMILY SSF51569 7 335 5.27E-144 T 28-03-2018 A6A12_RS14060 3423ef60d6a0c4fe695eef21d557233a 348 SMART SM01004 9 333 4.9E-243 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A6A12_RS14060 3423ef60d6a0c4fe695eef21d557233a 348 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 198 217 7.1E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A6A12_RS14060 3423ef60d6a0c4fe695eef21d557233a 348 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 252 268 7.1E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A6A12_RS14060 3423ef60d6a0c4fe695eef21d557233a 348 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 129 143 7.1E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A6A12_RS14060 3423ef60d6a0c4fe695eef21d557233a 348 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 307 326 7.1E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A6A12_RS14060 3423ef60d6a0c4fe695eef21d557233a 348 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 160 179 7.1E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A6A12_RS14060 3423ef60d6a0c4fe695eef21d557233a 348 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 277 292 7.1E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A6A12_RS14060 3423ef60d6a0c4fe695eef21d557233a 348 PIRSF PIRSF001415 2 336 2.2E-151 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A6A12_RS14060 3423ef60d6a0c4fe695eef21d557233a 348 Pfam PF00490 Delta-aminolevulinic acid dehydratase 12 332 8.2E-141 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A6A12_RS14060 3423ef60d6a0c4fe695eef21d557233a 348 Gene3D G3DSA:3.20.20.70 1 337 1.2E-153 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS14060 3423ef60d6a0c4fe695eef21d557233a 348 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 252 264 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 A6A12_RS05360 d03c78f25ce4643ddb658e5c648aef49 764 SUPERFAMILY SSF51726 396 758 2.35E-112 T 28-03-2018 A6A12_RS05360 d03c78f25ce4643ddb658e5c648aef49 764 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 431 753 6.8E-150 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A6A12_RS05360 d03c78f25ce4643ddb658e5c648aef49 764 Gene3D G3DSA:3.20.20.210 390 759 2.2E-121 T 28-03-2018 A6A12_RS05360 d03c78f25ce4643ddb658e5c648aef49 764 Gene3D G3DSA:3.20.20.210 3 389 5.9E-138 T 28-03-2018 A6A12_RS05360 d03c78f25ce4643ddb658e5c648aef49 764 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 3 758 35.81 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A6A12_RS05360 d03c78f25ce4643ddb658e5c648aef49 764 SUPERFAMILY SSF51726 5 393 1.2E-107 T 28-03-2018 A6A12_RS05360 d03c78f25ce4643ddb658e5c648aef49 764 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 8 757 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A6A12_RS05360 d03c78f25ce4643ddb658e5c648aef49 764 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 316 3.3E-120 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A6A12_RS05360 d03c78f25ce4643ddb658e5c648aef49 764 PIRSF PIRSF000382 2 763 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 A6A12_RS08995 297abf7812aed9643415dd62e9fb319c 59 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 27.084 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 A6A12_RS08995 297abf7812aed9643415dd62e9fb319c 59 Gene3D G3DSA:2.20.25.10 8 59 4.6E-20 T 28-03-2018 A6A12_RS08995 297abf7812aed9643415dd62e9fb319c 59 Pfam PF03966 Trm112p-like protein 2 41 7.2E-11 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 A6A12_RS08995 297abf7812aed9643415dd62e9fb319c 59 SUPERFAMILY SSF158997 1 54 2.49E-20 T 28-03-2018 A6A12_RS11540 45533c8945cbf7be8b3cafa8e4c00420 360 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 358 25.597 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A6A12_RS11540 45533c8945cbf7be8b3cafa8e4c00420 360 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A6A12_RS11540 45533c8945cbf7be8b3cafa8e4c00420 360 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 5.2E-6 T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A6A12_RS11540 45533c8945cbf7be8b3cafa8e4c00420 360 ProSitePatterns PS01348 MraY family signature 2. 189 200 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A6A12_RS11540 45533c8945cbf7be8b3cafa8e4c00420 360 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 37 360 1.3E-156 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 A6A12_RS11540 45533c8945cbf7be8b3cafa8e4c00420 360 Pfam PF00953 Glycosyl transferase family 4 99 283 5.7E-37 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 A6A12_RS07620 1563e626b3c7a0efd1b61cdef2de6825 543 SMART SM00304 212 266 1.2E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS07620 1563e626b3c7a0efd1b61cdef2de6825 543 Gene3D G3DSA:1.10.287.950 321 543 9.5E-50 T 28-03-2018 A6A12_RS07620 1563e626b3c7a0efd1b61cdef2de6825 543 SUPERFAMILY SSF58104 241 543 3.79E-70 T 28-03-2018 A6A12_RS07620 1563e626b3c7a0efd1b61cdef2de6825 543 Pfam PF12729 Four helix bundle sensory module for signal transduction 7 172 2.1E-17 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain A6A12_RS07620 1563e626b3c7a0efd1b61cdef2de6825 543 Gene3D G3DSA:1.10.287.1060 241 320 1.8E-4 T 28-03-2018 A6A12_RS07620 1563e626b3c7a0efd1b61cdef2de6825 543 Gene3D G3DSA:1.20.120.30 25 180 2.1E-9 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain A6A12_RS07620 1563e626b3c7a0efd1b61cdef2de6825 543 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 353 508 2.2E-38 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS07620 1563e626b3c7a0efd1b61cdef2de6825 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 1.2E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07620 1563e626b3c7a0efd1b61cdef2de6825 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 408 437 1.2E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07620 1563e626b3c7a0efd1b61cdef2de6825 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 379 406 1.2E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07620 1563e626b3c7a0efd1b61cdef2de6825 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 302 331 1.2E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07620 1563e626b3c7a0efd1b61cdef2de6825 543 SMART SM00283 281 542 1.7E-67 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS05535 393c70fd938e4cb32e9a5b0702c09c7d 88 SUPERFAMILY SSF52833 3 81 3.12E-21 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS05535 393c70fd938e4cb32e9a5b0702c09c7d 88 TIGRFAM TIGR02183 GRXA: glutaredoxin, GrxA family 2 85 1.4E-48 T 28-03-2018 IPR011902 Glutaredoxin, GrxA GO:0009055|GO:0015035|GO:0045454 A6A12_RS05535 393c70fd938e4cb32e9a5b0702c09c7d 88 PRINTS PR00160 Glutaredoxin signature 3 21 1.7E-11 T 28-03-2018 IPR014025 Glutaredoxin subgroup A6A12_RS05535 393c70fd938e4cb32e9a5b0702c09c7d 88 PRINTS PR00160 Glutaredoxin signature 66 79 1.7E-11 T 28-03-2018 IPR014025 Glutaredoxin subgroup A6A12_RS05535 393c70fd938e4cb32e9a5b0702c09c7d 88 PRINTS PR00160 Glutaredoxin signature 52 65 1.7E-11 T 28-03-2018 IPR014025 Glutaredoxin subgroup A6A12_RS05535 393c70fd938e4cb32e9a5b0702c09c7d 88 Gene3D G3DSA:3.40.30.10 2 80 2.3E-21 T 28-03-2018 A6A12_RS05535 393c70fd938e4cb32e9a5b0702c09c7d 88 Pfam PF00462 Glutaredoxin 3 69 1.1E-16 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 A6A12_RS13480 a3407ebd8c5bd78f9ece056412ca3100 356 Gene3D G3DSA:3.40.50.2000 160 348 5.9E-39 T 28-03-2018 A6A12_RS13480 a3407ebd8c5bd78f9ece056412ca3100 356 Gene3D G3DSA:3.40.50.2000 3 158 1.7E-30 T 28-03-2018 A6A12_RS13480 a3407ebd8c5bd78f9ece056412ca3100 356 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 75 306 5.9E-52 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 A6A12_RS13480 a3407ebd8c5bd78f9ece056412ca3100 356 SUPERFAMILY SSF53756 9 345 4.39E-81 T 28-03-2018 A6A12_RS09100 9ee9d65da5eb80c59a02093c5b78fe84 279 Pfam PF07840 FadR C-terminal domain 72 274 3.1E-67 T 28-03-2018 IPR028374 FadR, C-terminal domain GO:0000062|GO:0019217 A6A12_RS09100 9ee9d65da5eb80c59a02093c5b78fe84 279 SUPERFAMILY SSF46785 12 74 1.32E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09100 9ee9d65da5eb80c59a02093c5b78fe84 279 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 3.5E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A6A12_RS09100 9ee9d65da5eb80c59a02093c5b78fe84 279 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 3.5E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A6A12_RS09100 9ee9d65da5eb80c59a02093c5b78fe84 279 Hamap MF_00696 Fatty acid metabolism regulator protein [fadR]. 1 279 137.526 T 28-03-2018 IPR014178 Fatty acid response transcription factor FadR GO:0000062|GO:0003677|GO:0003700|GO:0019217 A6A12_RS09100 9ee9d65da5eb80c59a02093c5b78fe84 279 Gene3D G3DSA:1.20.120.530 80 279 7.6E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A6A12_RS09100 9ee9d65da5eb80c59a02093c5b78fe84 279 TIGRFAM TIGR02812 fadR_gamma: fatty acid metabolism transcriptional regulator FadR 2 276 9.4E-116 T 28-03-2018 IPR014178 Fatty acid response transcription factor FadR GO:0000062|GO:0003677|GO:0003700|GO:0019217 A6A12_RS09100 9ee9d65da5eb80c59a02093c5b78fe84 279 Gene3D G3DSA:1.10.10.10 1 79 2.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09100 9ee9d65da5eb80c59a02093c5b78fe84 279 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 71 1.6E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A6A12_RS09100 9ee9d65da5eb80c59a02093c5b78fe84 279 SUPERFAMILY SSF48008 178 270 4.84E-57 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A6A12_RS09100 9ee9d65da5eb80c59a02093c5b78fe84 279 SUPERFAMILY SSF48008 79 137 4.84E-57 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A6A12_RS09100 9ee9d65da5eb80c59a02093c5b78fe84 279 SMART SM00345 12 71 1.7E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A6A12_RS04730 b86a0c65664e4f840f5c3133a2ab2c11 357 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 18 346 4.7E-132 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A6A12_RS04730 b86a0c65664e4f840f5c3133a2ab2c11 357 Pfam PF00793 DAHP synthetase I family 44 334 5.0E-88 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A6A12_RS04730 b86a0c65664e4f840f5c3133a2ab2c11 357 SUPERFAMILY SSF51569 9 345 5.5E-115 T 28-03-2018 A6A12_RS04730 b86a0c65664e4f840f5c3133a2ab2c11 357 PIRSF PIRSF001361 1 351 1.0E-140 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 A6A12_RS04730 b86a0c65664e4f840f5c3133a2ab2c11 357 Gene3D G3DSA:3.20.20.70 8 353 3.1E-109 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS02720 1af07025252f9daff39bff380378fd89 289 SUPERFAMILY SSF52374 3 283 9.85E-83 T 28-03-2018 A6A12_RS02720 1af07025252f9daff39bff380378fd89 289 Gene3D G3DSA:3.40.50.620 109 220 2.8E-20 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS02720 1af07025252f9daff39bff380378fd89 289 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 3 268 1.5E-112 T 28-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 A6A12_RS02720 1af07025252f9daff39bff380378fd89 289 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 6 240 1.2E-42 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 A6A12_RS02720 1af07025252f9daff39bff380378fd89 289 PRINTS PR00987 Glutamyl-tRNA synthetase signature 184 192 6.1E-14 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A6A12_RS02720 1af07025252f9daff39bff380378fd89 289 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 6.1E-14 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A6A12_RS02720 1af07025252f9daff39bff380378fd89 289 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 6.1E-14 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A6A12_RS02720 1af07025252f9daff39bff380378fd89 289 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 6.1E-14 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A6A12_RS02720 1af07025252f9daff39bff380378fd89 289 PRINTS PR00987 Glutamyl-tRNA synthetase signature 168 178 6.1E-14 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 A6A12_RS02720 1af07025252f9daff39bff380378fd89 289 Gene3D G3DSA:3.40.50.620 3 108 8.6E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS02720 1af07025252f9daff39bff380378fd89 289 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 3 288 40.215 T 28-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 A6A12_RS03185 d7b7717c05b3d78c2409e81eae255335 520 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 5 511 1.7E-141 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A6A12_RS03185 d7b7717c05b3d78c2409e81eae255335 520 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 5 476 19.757 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A6A12_RS03185 d7b7717c05b3d78c2409e81eae255335 520 PIRSF PIRSF002869 1 518 1.1E-151 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A6A12_RS03185 d7b7717c05b3d78c2409e81eae255335 520 Pfam PF03023 MviN-like protein 30 483 1.7E-145 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A6A12_RS03185 d7b7717c05b3d78c2409e81eae255335 520 PRINTS PR01806 Virulence factor MviN signature 54 70 1.8E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A6A12_RS03185 d7b7717c05b3d78c2409e81eae255335 520 PRINTS PR01806 Virulence factor MviN signature 166 187 1.8E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A6A12_RS03185 d7b7717c05b3d78c2409e81eae255335 520 PRINTS PR01806 Virulence factor MviN signature 35 54 1.8E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A6A12_RS03185 d7b7717c05b3d78c2409e81eae255335 520 PRINTS PR01806 Virulence factor MviN signature 142 166 1.8E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A6A12_RS03185 d7b7717c05b3d78c2409e81eae255335 520 PRINTS PR01806 Virulence factor MviN signature 268 294 1.8E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A6A12_RS03185 d7b7717c05b3d78c2409e81eae255335 520 PRINTS PR01806 Virulence factor MviN signature 366 385 1.8E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A6A12_RS03185 d7b7717c05b3d78c2409e81eae255335 520 PRINTS PR01806 Virulence factor MviN signature 418 435 1.8E-77 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ A6A12_RS02840 83e11f10ee4687b0e97971709589ecb0 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 325 1.1E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS02840 83e11f10ee4687b0e97971709589ecb0 328 SUPERFAMILY SSF161098 93 324 3.53E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS02840 83e11f10ee4687b0e97971709589ecb0 328 Gene3D G3DSA:1.10.3720.10 2 314 4.4E-32 T 28-03-2018 A6A12_RS02715 d4cb2faf316c146e4af968779e78dc4d 455 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 7 449 37.32 T 28-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 A6A12_RS02715 d4cb2faf316c146e4af968779e78dc4d 455 Pfam PF01743 Poly A polymerase head domain 54 183 3.6E-39 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A6A12_RS02715 d4cb2faf316c146e4af968779e78dc4d 455 Gene3D G3DSA:3.30.460.10 20 180 1.4E-52 T 28-03-2018 A6A12_RS02715 d4cb2faf316c146e4af968779e78dc4d 455 Pfam PF12626 Polymerase A arginine-rich C-terminus 329 447 8.3E-38 T 28-03-2018 IPR025866 Polymerase A arginine-rich C-terminal domain A6A12_RS02715 d4cb2faf316c146e4af968779e78dc4d 455 SUPERFAMILY SSF81301 26 180 8.61E-41 T 28-03-2018 A6A12_RS02715 d4cb2faf316c146e4af968779e78dc4d 455 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 210 271 3.7E-21 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 A6A12_RS02715 d4cb2faf316c146e4af968779e78dc4d 455 SUPERFAMILY SSF81891 181 393 1.57E-48 T 28-03-2018 A6A12_RS02715 d4cb2faf316c146e4af968779e78dc4d 455 Gene3D G3DSA:1.10.3090.10 181 426 1.0E-43 T 28-03-2018 A6A12_RS02715 d4cb2faf316c146e4af968779e78dc4d 455 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 23 450 2.2E-158 T 28-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 A6A12_RS04580 7f99ac53256ab6fae119d98d9711a10c 1245 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 1199 1241 1.0E-15 T 28-03-2018 IPR020011 Motility protein FimV, C-terminal A6A12_RS04580 7f99ac53256ab6fae119d98d9711a10c 1245 Gene3D G3DSA:3.10.350.10 54 162 1.6E-6 T 28-03-2018 A6A12_RS04580 7f99ac53256ab6fae119d98d9711a10c 1245 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 71 143 3.8E-26 T 28-03-2018 IPR020012 Motility protein FimV, N-terminal A6A12_RS06570 3bebaf8907cd26fde1f8960788d78809 879 Pfam PF02470 MlaD protein 47 138 5.7E-13 T 28-03-2018 IPR003399 Mce/MlaD A6A12_RS06570 3bebaf8907cd26fde1f8960788d78809 879 Pfam PF02470 MlaD protein 400 463 6.9E-7 T 28-03-2018 IPR003399 Mce/MlaD A6A12_RS06570 3bebaf8907cd26fde1f8960788d78809 879 Pfam PF02470 MlaD protein 168 225 9.4E-6 T 28-03-2018 IPR003399 Mce/MlaD A6A12_RS06570 3bebaf8907cd26fde1f8960788d78809 879 Pfam PF02470 MlaD protein 639 713 4.7E-8 T 28-03-2018 IPR003399 Mce/MlaD A6A12_RS06570 3bebaf8907cd26fde1f8960788d78809 879 Pfam PF02470 MlaD protein 286 376 3.5E-7 T 28-03-2018 IPR003399 Mce/MlaD A6A12_RS11365 b3aa3c019fed09834b2b84005ea0bc21 427 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 85 367 4.5E-25 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A6A12_RS11365 b3aa3c019fed09834b2b84005ea0bc21 427 SUPERFAMILY SSF53686 1 424 3.01E-131 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A6A12_RS11365 b3aa3c019fed09834b2b84005ea0bc21 427 TIGRFAM TIGR00260 thrC: threonine synthase 51 391 1.3E-114 T 28-03-2018 IPR004450 Threonine synthase-like A6A12_RS11365 b3aa3c019fed09834b2b84005ea0bc21 427 Pfam PF14821 Threonine synthase N terminus 8 78 1.5E-8 T 28-03-2018 IPR029144 Threonine synthase, N-terminal A6A12_RS11365 b3aa3c019fed09834b2b84005ea0bc21 427 Gene3D G3DSA:3.90.1380.10 1 79 3.0E-15 T 28-03-2018 IPR029144 Threonine synthase, N-terminal A6A12_RS11365 b3aa3c019fed09834b2b84005ea0bc21 427 Gene3D G3DSA:3.40.50.1100 99 194 9.0E-20 T 28-03-2018 A6A12_RS11365 b3aa3c019fed09834b2b84005ea0bc21 427 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 95 109 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 A6A12_RS11365 b3aa3c019fed09834b2b84005ea0bc21 427 Gene3D G3DSA:3.40.50.1100 321 394 7.7E-13 T 28-03-2018 A6A12_RS11365 b3aa3c019fed09834b2b84005ea0bc21 427 Gene3D G3DSA:3.40.50.1100 195 318 1.0E-41 T 28-03-2018 A6A12_RS01110 a1f80a3f6390a544d3eb3dfd8d45d01d 160 SUPERFAMILY SSF55729 12 143 3.16E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS01110 a1f80a3f6390a544d3eb3dfd8d45d01d 160 Gene3D G3DSA:3.40.630.30 1 154 2.1E-10 T 28-03-2018 A6A12_RS01110 a1f80a3f6390a544d3eb3dfd8d45d01d 160 Pfam PF13508 Acetyltransferase (GNAT) domain 63 128 1.7E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A6A12_RS06150 cea6daf6f91443bdc8ee6a41017022f7 536 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 323 501 3.4E-41 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS06150 cea6daf6f91443bdc8ee6a41017022f7 536 SUPERFAMILY SSF58104 227 536 4.05E-70 T 28-03-2018 A6A12_RS06150 cea6daf6f91443bdc8ee6a41017022f7 536 SMART SM01049 36 126 3.9E-19 T 28-03-2018 IPR033480 Single Cache domain 2 A6A12_RS06150 cea6daf6f91443bdc8ee6a41017022f7 536 Gene3D G3DSA:1.10.287.950 179 311 3.1E-6 T 28-03-2018 A6A12_RS06150 cea6daf6f91443bdc8ee6a41017022f7 536 Gene3D G3DSA:1.10.287.950 312 536 2.3E-50 T 28-03-2018 A6A12_RS06150 cea6daf6f91443bdc8ee6a41017022f7 536 Pfam PF17200 Single Cache domain 2 42 183 2.4E-25 T 28-03-2018 IPR033480 Single Cache domain 2 A6A12_RS06150 cea6daf6f91443bdc8ee6a41017022f7 536 Gene3D G3DSA:3.30.450.20 31 178 7.8E-33 T 28-03-2018 A6A12_RS06150 cea6daf6f91443bdc8ee6a41017022f7 536 SMART SM00283 274 535 6.6E-69 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS06150 cea6daf6f91443bdc8ee6a41017022f7 536 SMART SM00304 260 312 37.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS06150 cea6daf6f91443bdc8ee6a41017022f7 536 SMART SM00304 207 259 6.9E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS06150 cea6daf6f91443bdc8ee6a41017022f7 536 Pfam PF00672 HAMP domain 207 250 2.2E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS02535 4c686e7c85eaafbcd04992bcda1f2009 521 SUPERFAMILY SSF55931 8 513 4.77E-204 T 28-03-2018 A6A12_RS02535 4c686e7c85eaafbcd04992bcda1f2009 521 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 8 515 9.1E-216 T 28-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A6A12_RS02535 4c686e7c85eaafbcd04992bcda1f2009 521 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 521 223.24 T 28-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A6A12_RS02535 4c686e7c85eaafbcd04992bcda1f2009 521 Pfam PF04262 Glutamate-cysteine ligase 12 378 4.5E-169 T 28-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 A6A12_RS10405 36f1ad90bc4810364629361712ea4b14 570 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 249 321 6.7E-9 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A6A12_RS10405 36f1ad90bc4810364629361712ea4b14 570 Gene3D G3DSA:3.40.50.300 1 337 2.3E-23 T 28-03-2018 A6A12_RS10405 36f1ad90bc4810364629361712ea4b14 570 SUPERFAMILY SSF52540 4 112 1.59E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS10405 36f1ad90bc4810364629361712ea4b14 570 SUPERFAMILY SSF52540 159 335 1.59E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS10405 36f1ad90bc4810364629361712ea4b14 570 Pfam PF13476 AAA domain 7 61 1.3E-9 T 28-03-2018 A6A12_RS11405 95958f6e22685fb32ad0a1ed904b054c 311 SMART SM00729 23 247 2.5E-42 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A6A12_RS11405 95958f6e22685fb32ad0a1ed904b054c 311 Gene3D G3DSA:3.20.20.70 2 295 3.8E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS11405 95958f6e22685fb32ad0a1ed904b054c 311 SUPERFAMILY SSF102114 13 268 1.29E-48 T 28-03-2018 A6A12_RS11405 95958f6e22685fb32ad0a1ed904b054c 311 Pfam PF16199 Radical_SAM C-terminal domain 209 279 2.7E-18 T 28-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 A6A12_RS11405 95958f6e22685fb32ad0a1ed904b054c 311 Pfam PF04055 Radical SAM superfamily 43 201 5.2E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A6A12_RS11405 95958f6e22685fb32ad0a1ed904b054c 311 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 6 301 3.1E-135 T 28-03-2018 IPR005911 Protein YhcC-like GO:0051536 A6A12_RS07475 cf5f6a6efcb98b0847fa610aacc20750 129 Gene3D G3DSA:1.10.10.10 57 129 2.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS10640 3eea6ef1913cc7ca10ff178fa3519836 235 Pfam PF03963 Flagellar hook capping protein - N-terminal region 22 85 1.6E-21 T 28-03-2018 IPR005648 Flagellar hook capping protein A6A12_RS10640 3eea6ef1913cc7ca10ff178fa3519836 235 Pfam PF13860 FlgD Ig-like domain 117 184 5.3E-20 T 28-03-2018 IPR025965 FlgD Ig-like domain A6A12_RS10640 3eea6ef1913cc7ca10ff178fa3519836 235 Pfam PF13861 FlgD Tudor-like domain 93 229 2.8E-15 T 28-03-2018 IPR025963 FlgD Tudor-like domain A6A12_RS07635 e7c8e77fded9abe440ac6d224cecc46d 318 Gene3D G3DSA:3.60.15.10 33 317 2.6E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS07635 e7c8e77fded9abe440ac6d224cecc46d 318 SUPERFAMILY SSF56281 35 306 1.27E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS07635 e7c8e77fded9abe440ac6d224cecc46d 318 Pfam PF12706 Beta-lactamase superfamily domain 64 274 4.8E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS06140 4149b65ffe5d757269cc7ad6173a3398 414 Gene3D G3DSA:3.40.50.720 1 128 2.7E-9 T 28-03-2018 A6A12_RS06140 4149b65ffe5d757269cc7ad6173a3398 414 Gene3D G3DSA:3.30.360.10 150 343 1.0E-52 T 28-03-2018 A6A12_RS06140 4149b65ffe5d757269cc7ad6173a3398 414 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 149 393 5.0E-28 T 28-03-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 A6A12_RS06140 4149b65ffe5d757269cc7ad6173a3398 414 SUPERFAMILY SSF51735 1 179 2.34E-17 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS06140 4149b65ffe5d757269cc7ad6173a3398 414 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 145 2.1E-32 T 28-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 A6A12_RS09135 2d7c70a2a004a9c25899ecc7b7631d05 429 Gene3D G3DSA:3.90.1150.10 4 170 2.5E-45 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS09135 2d7c70a2a004a9c25899ecc7b7631d05 429 SUPERFAMILY SSF53383 3 419 9.11E-134 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS09135 2d7c70a2a004a9c25899ecc7b7631d05 429 PIRSF PIRSF000521 21 419 9.9E-32 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A6A12_RS09135 2d7c70a2a004a9c25899ecc7b7631d05 429 Pfam PF00202 Aminotransferase class-III 24 416 1.2E-127 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A6A12_RS09135 2d7c70a2a004a9c25899ecc7b7631d05 429 Gene3D G3DSA:3.40.640.10 180 329 2.3E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS09135 2d7c70a2a004a9c25899ecc7b7631d05 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A6A12_RS09135 2d7c70a2a004a9c25899ecc7b7631d05 429 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 1 421 48.415 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 A6A12_RS09135 2d7c70a2a004a9c25899ecc7b7631d05 429 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 10 418 4.2E-178 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 A6A12_RS02355 6524b8a5e6ba402a40023143b7b890c2 282 SUPERFAMILY SSF53474 3 279 5.22E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS02355 6524b8a5e6ba402a40023143b7b890c2 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 223 237 1.8E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A6A12_RS02355 6524b8a5e6ba402a40023143b7b890c2 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 56 71 1.8E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A6A12_RS02355 6524b8a5e6ba402a40023143b7b890c2 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 1.8E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A6A12_RS02355 6524b8a5e6ba402a40023143b7b890c2 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 1.8E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A6A12_RS02355 6524b8a5e6ba402a40023143b7b890c2 282 Gene3D G3DSA:3.40.50.1820 6 282 4.1E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS02355 6524b8a5e6ba402a40023143b7b890c2 282 Pfam PF00561 alpha/beta hydrolase fold 32 141 2.5E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A6A12_RS02355 6524b8a5e6ba402a40023143b7b890c2 282 PRINTS PR00412 Epoxide hydrolase signature 254 276 5.3E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A6A12_RS02355 6524b8a5e6ba402a40023143b7b890c2 282 PRINTS PR00412 Epoxide hydrolase signature 115 128 5.3E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A6A12_RS02355 6524b8a5e6ba402a40023143b7b890c2 282 PRINTS PR00412 Epoxide hydrolase signature 56 71 5.3E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A6A12_RS13435 30c0dfe060c3d1f23b029b06c9e72e57 354 SUPERFAMILY SSF53756 13 353 3.45E-99 T 28-03-2018 A6A12_RS13435 30c0dfe060c3d1f23b029b06c9e72e57 354 Gene3D G3DSA:3.40.50.2000 5 154 6.6E-36 T 28-03-2018 A6A12_RS13435 30c0dfe060c3d1f23b029b06c9e72e57 354 TIGRFAM TIGR02195 heptsyl_trn_II: lipopolysaccharide heptosyltransferase II 14 352 2.1E-145 T 28-03-2018 IPR011910 ADP-heptose--LPS heptosyltransferase 2 GO:0009103|GO:0016757 A6A12_RS13435 30c0dfe060c3d1f23b029b06c9e72e57 354 Gene3D G3DSA:3.40.50.2000 171 354 4.3E-47 T 28-03-2018 A6A12_RS13435 30c0dfe060c3d1f23b029b06c9e72e57 354 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 81 333 8.5E-72 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 A6A12_RS04100 4a954c56f170fa03f1a45950eea55efb 455 SUPERFAMILY SSF102405 121 326 1.13E-41 T 28-03-2018 A6A12_RS04100 4a954c56f170fa03f1a45950eea55efb 455 Pfam PF03641 Possible lysine decarboxylase 187 326 1.0E-35 T 28-03-2018 IPR031100 LOG family A6A12_RS04100 4a954c56f170fa03f1a45950eea55efb 455 Pfam PF14793 Domain of unknown function (DUF4478) 4 109 8.2E-51 T 28-03-2018 IPR027820 Domain of unknown function DUF4478 A6A12_RS04100 4a954c56f170fa03f1a45950eea55efb 455 Pfam PF11892 Domain of unknown function (DUF3412) 330 450 4.9E-57 T 28-03-2018 IPR021826 Domain of unknown function DUF3412 A6A12_RS04100 4a954c56f170fa03f1a45950eea55efb 455 Gene3D G3DSA:3.40.50.450 121 450 3.4E-101 T 28-03-2018 A6A12_RS04100 4a954c56f170fa03f1a45950eea55efb 455 Gene3D G3DSA:3.30.1850.10 3 111 5.1E-52 T 28-03-2018 IPR027820 Domain of unknown function DUF4478 A6A12_RS09245 841349f63d0d1a301c51f86f77d28e9a 245 Gene3D G3DSA:3.40.47.10 15 207 1.2E-4 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS09245 841349f63d0d1a301c51f86f77d28e9a 245 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 32 242 2.2E-75 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal A6A12_RS09245 841349f63d0d1a301c51f86f77d28e9a 245 SUPERFAMILY SSF53901 37 161 1.46E-7 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 A6A12_RS12625 95d9dcf4e2392c601c0c3e819ae3c1a9 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 3.7E-39 T 28-03-2018 A6A12_RS12625 95d9dcf4e2392c601c0c3e819ae3c1a9 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 325 3.7E-39 T 28-03-2018 A6A12_RS12625 95d9dcf4e2392c601c0c3e819ae3c1a9 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 3.7E-39 T 28-03-2018 A6A12_RS12625 95d9dcf4e2392c601c0c3e819ae3c1a9 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 305 3.7E-39 T 28-03-2018 A6A12_RS12625 95d9dcf4e2392c601c0c3e819ae3c1a9 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 289 3.7E-39 T 28-03-2018 A6A12_RS12625 95d9dcf4e2392c601c0c3e819ae3c1a9 478 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 325 341 3.7E-39 T 28-03-2018 A6A12_RS12625 95d9dcf4e2392c601c0c3e819ae3c1a9 478 Pfam PF01494 FAD binding domain 6 339 2.3E-70 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 A6A12_RS12625 95d9dcf4e2392c601c0c3e819ae3c1a9 478 Gene3D G3DSA:3.30.9.10 283 371 5.3E-18 T 28-03-2018 A6A12_RS12625 95d9dcf4e2392c601c0c3e819ae3c1a9 478 Gene3D G3DSA:3.30.9.10 173 282 3.3E-19 T 28-03-2018 A6A12_RS12625 95d9dcf4e2392c601c0c3e819ae3c1a9 478 SUPERFAMILY SSF51905 5 174 2.21E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS12625 95d9dcf4e2392c601c0c3e819ae3c1a9 478 SUPERFAMILY SSF51905 260 347 2.21E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS12625 95d9dcf4e2392c601c0c3e819ae3c1a9 478 SUPERFAMILY SSF54373 180 265 3.61E-22 T 28-03-2018 A6A12_RS12625 95d9dcf4e2392c601c0c3e819ae3c1a9 478 Gene3D G3DSA:3.50.50.60 6 172 7.6E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS02865 589ff2f7f8c58497a690a3e8800d2756 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A6A12_RS02865 589ff2f7f8c58497a690a3e8800d2756 431 Gene3D G3DSA:3.90.1150.10 1 182 3.1E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS02865 589ff2f7f8c58497a690a3e8800d2756 431 Pfam PF00202 Aminotransferase class-III 33 395 6.3E-75 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A6A12_RS02865 589ff2f7f8c58497a690a3e8800d2756 431 SUPERFAMILY SSF53383 1 423 3.8E-133 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS02865 589ff2f7f8c58497a690a3e8800d2756 431 Gene3D G3DSA:3.90.1150.10 310 431 4.2E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS02865 589ff2f7f8c58497a690a3e8800d2756 431 Gene3D G3DSA:3.40.640.10 183 309 2.9E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS02865 589ff2f7f8c58497a690a3e8800d2756 431 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 426 104.891 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A6A12_RS02865 589ff2f7f8c58497a690a3e8800d2756 431 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 3 424 3.9E-194 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 A6A12_RS10265 bc732a29610c44eca7dcf6951c2f8ba5 376 PRINTS PR00207 Flagellin signature 37 54 5.4E-27 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A6A12_RS10265 bc732a29610c44eca7dcf6951c2f8ba5 376 PRINTS PR00207 Flagellin signature 76 95 5.4E-27 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A6A12_RS10265 bc732a29610c44eca7dcf6951c2f8ba5 376 PRINTS PR00207 Flagellin signature 111 134 5.4E-27 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 A6A12_RS10265 bc732a29610c44eca7dcf6951c2f8ba5 376 SUPERFAMILY SSF64518 1 375 6.93E-99 T 28-03-2018 A6A12_RS10265 bc732a29610c44eca7dcf6951c2f8ba5 376 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 3.3E-43 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A6A12_RS10265 bc732a29610c44eca7dcf6951c2f8ba5 376 Gene3D G3DSA:1.20.1330.10 192 348 3.4E-26 T 28-03-2018 A6A12_RS10265 bc732a29610c44eca7dcf6951c2f8ba5 376 Gene3D G3DSA:1.20.1330.10 40 191 4.3E-47 T 28-03-2018 A6A12_RS10265 bc732a29610c44eca7dcf6951c2f8ba5 376 Pfam PF07196 Flagellin hook IN motif 193 248 3.2E-12 T 28-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 A6A12_RS10265 bc732a29610c44eca7dcf6951c2f8ba5 376 Pfam PF00700 Bacterial flagellin C-terminal helical region 291 375 5.6E-26 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A6A12_RS00900 489e681faa2b2560165fd562f948ae1b 403 SUPERFAMILY SSF53067 2 143 4.66E-40 T 28-03-2018 A6A12_RS00900 489e681faa2b2560165fd562f948ae1b 403 TIGRFAM TIGR01709 typeII_sec_gspL: type II secretion system protein L 5 402 1.8E-99 T 28-03-2018 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 A6A12_RS00900 489e681faa2b2560165fd562f948ae1b 403 PIRSF PIRSF015761 4 160 8.4E-12 T 28-03-2018 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 A6A12_RS00900 489e681faa2b2560165fd562f948ae1b 403 PIRSF PIRSF015761 202 403 3.8E-19 T 28-03-2018 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 A6A12_RS00900 489e681faa2b2560165fd562f948ae1b 403 Pfam PF05134 Type II secretion system (T2SS), protein L 5 239 1.6E-68 T 28-03-2018 IPR024230 GspL, cytoplasmic actin-ATPase-like domain A6A12_RS00900 489e681faa2b2560165fd562f948ae1b 403 SUPERFAMILY SSF53067 146 238 9.71E-21 T 28-03-2018 A6A12_RS00900 489e681faa2b2560165fd562f948ae1b 403 Pfam PF12693 GspL periplasmic domain 245 402 3.3E-48 T 28-03-2018 IPR025691 GspL periplasmic domain A6A12_RS11510 dad92e218196befc8cc364068113e4be 420 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 385 7.2E-151 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 A6A12_RS11510 dad92e218196befc8cc364068113e4be 420 Hamap MF_02033 Cell division protein FtsA [ftsA]. 6 420 29.236 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 A6A12_RS11510 dad92e218196befc8cc364068113e4be 420 Gene3D G3DSA:3.30.420.40 1 188 7.8E-34 T 28-03-2018 A6A12_RS11510 dad92e218196befc8cc364068113e4be 420 SUPERFAMILY SSF53067 8 221 1.09E-58 T 28-03-2018 A6A12_RS11510 dad92e218196befc8cc364068113e4be 420 Gene3D G3DSA:3.30.420.40 197 244 1.8E-4 T 28-03-2018 A6A12_RS11510 dad92e218196befc8cc364068113e4be 420 SMART SM00842 10 196 4.7E-95 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 A6A12_RS11510 dad92e218196befc8cc364068113e4be 420 PIRSF PIRSF003101 1 420 2.8E-146 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 A6A12_RS11510 dad92e218196befc8cc364068113e4be 420 SUPERFAMILY SSF53067 198 384 1.68E-44 T 28-03-2018 A6A12_RS11510 dad92e218196befc8cc364068113e4be 420 Pfam PF02491 SHS2 domain inserted in FTSA 85 161 4.8E-28 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 A6A12_RS11510 dad92e218196befc8cc364068113e4be 420 Gene3D G3DSA:3.30.420.40 293 386 0.0046 T 28-03-2018 A6A12_RS11510 dad92e218196befc8cc364068113e4be 420 Gene3D G3DSA:3.90.640.10 245 292 2.7E-20 T 28-03-2018 A6A12_RS11510 dad92e218196befc8cc364068113e4be 420 Pfam PF14450 Cell division protein FtsA 207 381 2.2E-24 T 28-03-2018 A6A12_RS02665 8fc4ce0d03f9dcdc3ca899fae3542a34 205 SUPERFAMILY SSF46689 9 85 8.48E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS02665 8fc4ce0d03f9dcdc3ca899fae3542a34 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A6A12_RS02665 8fc4ce0d03f9dcdc3ca899fae3542a34 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A6A12_RS02665 8fc4ce0d03f9dcdc3ca899fae3542a34 205 SUPERFAMILY SSF48498 108 198 1.01E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A6A12_RS02665 8fc4ce0d03f9dcdc3ca899fae3542a34 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 5.5E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A6A12_RS02665 8fc4ce0d03f9dcdc3ca899fae3542a34 205 Gene3D G3DSA:1.10.357.10 2 205 1.6E-28 T 28-03-2018 A6A12_RS03705 c1e1d37db6a3157a2edc195069396c02 195 SUPERFAMILY SSF53335 4 181 1.28E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS03705 c1e1d37db6a3157a2edc195069396c02 195 Pfam PF13649 Methyltransferase domain 39 125 3.5E-11 T 28-03-2018 A6A12_RS03705 c1e1d37db6a3157a2edc195069396c02 195 Gene3D G3DSA:3.40.50.150 2 195 6.4E-27 T 28-03-2018 A6A12_RS01690 5e496ac5cbe0c040cf1380667027bc23 481 Pfam PF01523 Putative modulator of DNA gyrase 35 332 1.4E-64 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A6A12_RS01690 5e496ac5cbe0c040cf1380667027bc23 481 PIRSF PIRSF004919 15 481 3.0E-143 T 28-03-2018 IPR025502 TldD A6A12_RS01690 5e496ac5cbe0c040cf1380667027bc23 481 SUPERFAMILY SSF111283 18 480 3.01E-129 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A6A12_RS01690 5e496ac5cbe0c040cf1380667027bc23 481 Gene3D G3DSA:3.30.2290.10 16 240 9.6E-56 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain A6A12_RS02635 e1e8cc89754b77567f3b61b6468ec5a7 257 SUPERFAMILY SSF52833 113 255 4.5E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS02635 e1e8cc89754b77567f3b61b6468ec5a7 257 Pfam PF13098 Thioredoxin-like domain 125 253 7.1E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS02635 e1e8cc89754b77567f3b61b6468ec5a7 257 Gene3D G3DSA:3.10.450.70 35 95 1.3E-12 T 28-03-2018 A6A12_RS02635 e1e8cc89754b77567f3b61b6468ec5a7 257 SUPERFAMILY SSF54423 41 94 4.71E-11 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal A6A12_RS02635 e1e8cc89754b77567f3b61b6468ec5a7 257 Pfam PF10411 Disulfide bond isomerase protein N-terminus 44 93 4.4E-12 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal A6A12_RS02635 e1e8cc89754b77567f3b61b6468ec5a7 257 ProSitePatterns PS00194 Thioredoxin family active site. 132 150 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A6A12_RS02635 e1e8cc89754b77567f3b61b6468ec5a7 257 Gene3D G3DSA:3.40.30.10 116 257 1.1E-23 T 28-03-2018 A6A12_RS09830 6694d25be02e3c08c76802e6880bf620 405 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 4 115 3.4E-28 T 28-03-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI A6A12_RS09830 6694d25be02e3c08c76802e6880bf620 405 SUPERFAMILY SSF48452 162 267 1.71E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS09830 6694d25be02e3c08c76802e6880bf620 405 Gene3D G3DSA:1.25.40.10 153 298 3.2E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS09830 6694d25be02e3c08c76802e6880bf620 405 Pfam PF14559 Tetratricopeptide repeat 178 245 5.1E-8 T 28-03-2018 A6A12_RS14020 c55fb00274f3b70d89cac5d14c596ae8 296 Pfam PF03466 LysR substrate binding domain 89 290 1.2E-36 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS14020 c55fb00274f3b70d89cac5d14c596ae8 296 Gene3D G3DSA:3.40.190.10 193 268 4.7E-10 T 28-03-2018 A6A12_RS14020 c55fb00274f3b70d89cac5d14c596ae8 296 Gene3D G3DSA:3.40.190.10 83 192 4.0E-17 T 28-03-2018 A6A12_RS14020 c55fb00274f3b70d89cac5d14c596ae8 296 Gene3D G3DSA:1.10.10.10 1 82 1.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS14020 c55fb00274f3b70d89cac5d14c596ae8 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 6.0E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS14020 c55fb00274f3b70d89cac5d14c596ae8 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS14020 c55fb00274f3b70d89cac5d14c596ae8 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS14020 c55fb00274f3b70d89cac5d14c596ae8 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.5E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS14020 c55fb00274f3b70d89cac5d14c596ae8 296 SUPERFAMILY SSF53850 89 291 2.65E-32 T 28-03-2018 A6A12_RS14020 c55fb00274f3b70d89cac5d14c596ae8 296 SUPERFAMILY SSF46785 1 85 7.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS04825 84545a1c16bb9b71805c5b06577070c6 213 Hamap MF_00551 Uridine kinase [udk]. 4 212 39.199 T 28-03-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 A6A12_RS04825 84545a1c16bb9b71805c5b06577070c6 213 SUPERFAMILY SSF52540 6 204 2.82E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS04825 84545a1c16bb9b71805c5b06577070c6 213 TIGRFAM TIGR00235 udk: uridine kinase 3 211 2.3E-90 T 28-03-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 A6A12_RS04825 84545a1c16bb9b71805c5b06577070c6 213 Gene3D G3DSA:3.40.50.300 3 213 2.0E-55 T 28-03-2018 A6A12_RS04825 84545a1c16bb9b71805c5b06577070c6 213 PRINTS PR00988 Uridine kinase signature 178 191 1.3E-36 T 28-03-2018 A6A12_RS04825 84545a1c16bb9b71805c5b06577070c6 213 PRINTS PR00988 Uridine kinase signature 156 167 1.3E-36 T 28-03-2018 A6A12_RS04825 84545a1c16bb9b71805c5b06577070c6 213 PRINTS PR00988 Uridine kinase signature 142 152 1.3E-36 T 28-03-2018 A6A12_RS04825 84545a1c16bb9b71805c5b06577070c6 213 PRINTS PR00988 Uridine kinase signature 41 52 1.3E-36 T 28-03-2018 A6A12_RS04825 84545a1c16bb9b71805c5b06577070c6 213 PRINTS PR00988 Uridine kinase signature 7 24 1.3E-36 T 28-03-2018 A6A12_RS04825 84545a1c16bb9b71805c5b06577070c6 213 PRINTS PR00988 Uridine kinase signature 86 101 1.3E-36 T 28-03-2018 A6A12_RS04825 84545a1c16bb9b71805c5b06577070c6 213 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 9 198 3.6E-42 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 A6A12_RS11095 1d7b9d961324e394608ba59f059917c3 181 PIRSF PIRSF001467 7 180 3.1E-25 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 A6A12_RS11095 1d7b9d961324e394608ba59f059917c3 181 Gene3D G3DSA:2.40.100.10 13 181 8.8E-47 T 28-03-2018 IPR029000 Cyclophilin-like domain A6A12_RS11095 1d7b9d961324e394608ba59f059917c3 181 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 56 73 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 A6A12_RS11095 1d7b9d961324e394608ba59f059917c3 181 SUPERFAMILY SSF50891 19 179 2.19E-54 T 28-03-2018 IPR029000 Cyclophilin-like domain A6A12_RS11095 1d7b9d961324e394608ba59f059917c3 181 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 35 50 3.7E-11 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A6A12_RS11095 1d7b9d961324e394608ba59f059917c3 181 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 135 150 3.7E-11 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A6A12_RS11095 1d7b9d961324e394608ba59f059917c3 181 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 61 73 3.7E-11 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A6A12_RS11095 1d7b9d961324e394608ba59f059917c3 181 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 22 177 2.6E-43 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A6A12_RS03510 58f5fc6c33db8cfa77130a78792fc607 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 2.2E-58 T 28-03-2018 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0051536|GO:0097428 A6A12_RS03510 58f5fc6c33db8cfa77130a78792fc607 107 TIGRFAM TIGR01997 sufA_proteo: FeS assembly scaffold SufA 2 107 1.5E-41 T 28-03-2018 IPR011298 FeS assembly scaffold SufA GO:0097428 A6A12_RS03510 58f5fc6c33db8cfa77130a78792fc607 107 SUPERFAMILY SSF89360 1 96 1.14E-34 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A6A12_RS03510 58f5fc6c33db8cfa77130a78792fc607 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 5.8E-27 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A6A12_RS03510 58f5fc6c33db8cfa77130a78792fc607 107 Gene3D G3DSA:2.60.300.12 2 107 5.6E-40 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 A6A12_RS03510 58f5fc6c33db8cfa77130a78792fc607 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 A6A12_RS03510 58f5fc6c33db8cfa77130a78792fc607 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 7.7E-39 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 A6A12_RS02620 a111221c6b60ac0ce475a7845a12b002 190 Gene3D G3DSA:3.40.80.10 8 190 3.7E-51 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A6A12_RS02620 a111221c6b60ac0ce475a7845a12b002 190 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 33 174 5.4E-30 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A6A12_RS02620 a111221c6b60ac0ce475a7845a12b002 190 SUPERFAMILY SSF55846 9 186 3.8E-66 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A6A12_RS02620 a111221c6b60ac0ce475a7845a12b002 190 SMART SM00644 23 174 2.9E-56 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 A6A12_RS04370 f70f33e371dfa86a41b86a7db2b43627 156 Pfam PF02590 Predicted SPOUT methyltransferase 1 154 2.6E-49 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS04370 f70f33e371dfa86a41b86a7db2b43627 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 27.687 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS04370 f70f33e371dfa86a41b86a7db2b43627 156 SUPERFAMILY SSF75217 1 154 1.83E-50 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases A6A12_RS04370 f70f33e371dfa86a41b86a7db2b43627 156 PIRSF PIRSF004505 1 155 1.5E-44 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS04370 f70f33e371dfa86a41b86a7db2b43627 156 Gene3D G3DSA:3.40.1280.10 1 155 1.6E-52 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A6A12_RS04370 f70f33e371dfa86a41b86a7db2b43627 156 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 156 1.4E-77 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS09485 7986f2fdd8ad81a2476f13b7cb947125 143 Pfam PF09619 Type III secretion system lipoprotein chaperone (YscW) 32 136 1.9E-42 T 28-03-2018 A6A12_RS06520 3962918a992b6eff00176d14ec334253 342 SMART SM00062 38 267 1.2E-54 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS06520 3962918a992b6eff00176d14ec334253 342 SUPERFAMILY SSF53850 29 259 7.43E-50 T 28-03-2018 A6A12_RS06520 3962918a992b6eff00176d14ec334253 342 Gene3D G3DSA:3.40.190.10 28 140 2.9E-19 T 28-03-2018 A6A12_RS06520 3962918a992b6eff00176d14ec334253 342 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 257 4.9E-31 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS06520 3962918a992b6eff00176d14ec334253 342 Gene3D G3DSA:3.40.190.10 141 270 1.0E-16 T 28-03-2018 A6A12_RS08225 348d24e3efabb0f584d3b6822007544c 337 Hamap MF_00737 Formimidoylglutamase [hutG]. 10 332 41.72 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 A6A12_RS08225 348d24e3efabb0f584d3b6822007544c 337 Pfam PF00491 Arginase family 52 330 2.6E-62 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 A6A12_RS08225 348d24e3efabb0f584d3b6822007544c 337 PRINTS PR00116 Arginase signature 131 146 1.4E-5 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 A6A12_RS08225 348d24e3efabb0f584d3b6822007544c 337 PRINTS PR00116 Arginase signature 257 286 1.4E-5 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 A6A12_RS08225 348d24e3efabb0f584d3b6822007544c 337 PIRSF PIRSF036979 28 337 3.1E-30 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 A6A12_RS08225 348d24e3efabb0f584d3b6822007544c 337 Gene3D G3DSA:3.40.800.10 5 337 8.8E-86 T 28-03-2018 A6A12_RS08225 348d24e3efabb0f584d3b6822007544c 337 ProSitePatterns PS01053 Arginase family signature. 260 281 - T 28-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 A6A12_RS08225 348d24e3efabb0f584d3b6822007544c 337 SUPERFAMILY SSF52768 15 334 4.68E-85 T 28-03-2018 A6A12_RS08225 348d24e3efabb0f584d3b6822007544c 337 TIGRFAM TIGR01227 hutG: formimidoylglutamase 15 332 2.8E-114 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 A6A12_RS08205 3f2b15d1f452e2df064a76bef56eef00 106 ProDom PD020447 UPF0263 YCIU HD0986 VV1228 UNCHARACTERIZED 3D-STRUCTURE VV13059 BCR PM0536 VC1208 18 104 7.0E-33 T 28-03-2018 IPR007376 dsDNA mimic, putative A6A12_RS08205 3f2b15d1f452e2df064a76bef56eef00 106 Hamap MF_00680 UPF0263 protein YciU [yciU]. 1 106 36.477 T 28-03-2018 IPR007376 dsDNA mimic, putative A6A12_RS08205 3f2b15d1f452e2df064a76bef56eef00 106 PIRSF PIRSF004916 1 105 4.3E-51 T 28-03-2018 IPR007376 dsDNA mimic, putative A6A12_RS08205 3f2b15d1f452e2df064a76bef56eef00 106 Pfam PF04269 Protein of unknown function, DUF440 5 105 5.1E-45 T 28-03-2018 IPR007376 dsDNA mimic, putative A6A12_RS08205 3f2b15d1f452e2df064a76bef56eef00 106 SUPERFAMILY SSF102816 3 105 1.31E-47 T 28-03-2018 IPR007376 dsDNA mimic, putative A6A12_RS08205 3f2b15d1f452e2df064a76bef56eef00 106 Gene3D G3DSA:3.10.450.140 6 104 2.8E-44 T 28-03-2018 IPR007376 dsDNA mimic, putative A6A12_RS03055 f023cb806e57eebb6cfaffc7e71df0e4 411 Pfam PF00271 Helicase conserved C-terminal domain 234 341 3.1E-32 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS03055 f023cb806e57eebb6cfaffc7e71df0e4 411 SUPERFAMILY SSF52540 76 357 7.71E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03055 f023cb806e57eebb6cfaffc7e71df0e4 411 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A6A12_RS03055 f023cb806e57eebb6cfaffc7e71df0e4 411 SMART SM00487 22 224 7.8E-57 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS03055 f023cb806e57eebb6cfaffc7e71df0e4 411 Pfam PF00270 DEAD/DEAH box helicase 27 194 1.0E-45 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A6A12_RS03055 f023cb806e57eebb6cfaffc7e71df0e4 411 SMART SM00490 257 341 3.7E-32 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS03055 f023cb806e57eebb6cfaffc7e71df0e4 411 Gene3D G3DSA:3.40.50.300 229 386 4.2E-45 T 28-03-2018 A6A12_RS03055 f023cb806e57eebb6cfaffc7e71df0e4 411 Hamap MF_00967 ATP-dependent RNA helicase SrmB [srmB]. 3 411 49.923 T 28-03-2018 IPR028621 ATP-dependent RNA helicase SrmB GO:0000027|GO:0004004 A6A12_RS03055 f023cb806e57eebb6cfaffc7e71df0e4 411 Gene3D G3DSA:3.40.50.300 1 228 8.4E-58 T 28-03-2018 A6A12_RS07785 63a24563287796dd6474337bd7df07d3 731 PRINTS PR01035 Tetracycline resistance protein signature 604 625 1.6E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A6A12_RS07785 63a24563287796dd6474337bd7df07d3 731 PRINTS PR01035 Tetracycline resistance protein signature 458 480 1.6E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A6A12_RS07785 63a24563287796dd6474337bd7df07d3 731 PRINTS PR01035 Tetracycline resistance protein signature 339 355 1.6E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A6A12_RS07785 63a24563287796dd6474337bd7df07d3 731 Pfam PF07690 Major Facilitator Superfamily 552 727 1.9E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A6A12_RS07785 63a24563287796dd6474337bd7df07d3 731 Pfam PF07690 Major Facilitator Superfamily 338 520 4.5E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A6A12_RS07785 63a24563287796dd6474337bd7df07d3 731 SUPERFAMILY SSF103473 337 724 6.41E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain A6A12_RS07785 63a24563287796dd6474337bd7df07d3 731 Gene3D G3DSA:1.20.1250.20 528 726 4.5E-14 T 28-03-2018 A6A12_RS07785 63a24563287796dd6474337bd7df07d3 731 Gene3D G3DSA:1.20.1250.20 288 522 3.8E-24 T 28-03-2018 A6A12_RS02730 c58b7191ee8a5676d6f81679476aaeaa 246 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 246 55.79 T 28-03-2018 IPR005224 Sugar fermentation stimulation protein A6A12_RS02730 c58b7191ee8a5676d6f81679476aaeaa 246 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 2 240 2.0E-74 T 28-03-2018 IPR005224 Sugar fermentation stimulation protein A6A12_RS02730 c58b7191ee8a5676d6f81679476aaeaa 246 Pfam PF03749 Sugar fermentation stimulation protein 13 238 2.2E-75 T 28-03-2018 IPR005224 Sugar fermentation stimulation protein A6A12_RS10365 906de046a93631c07204d7429c3a7323 154 Pfam PF00578 AhpC/TSA family 6 133 3.9E-37 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A6A12_RS10365 906de046a93631c07204d7429c3a7323 154 SUPERFAMILY SSF52833 3 153 1.11E-47 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS10365 906de046a93631c07204d7429c3a7323 154 Gene3D G3DSA:3.40.30.10 1 151 3.4E-40 T 28-03-2018 A6A12_RS10365 906de046a93631c07204d7429c3a7323 154 PIRSF PIRSF000239 1 146 8.1E-18 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A6A12_RS09025 75e507bb5fdfb08a35ae8cb8351c5693 228 SMART SM00382 33 221 8.7E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS09025 75e507bb5fdfb08a35ae8cb8351c5693 228 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 4 223 3.5E-109 T 28-03-2018 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0006810|GO:0016020 A6A12_RS09025 75e507bb5fdfb08a35ae8cb8351c5693 228 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS09025 75e507bb5fdfb08a35ae8cb8351c5693 228 Gene3D G3DSA:3.40.50.300 1 228 1.1E-61 T 28-03-2018 A6A12_RS09025 75e507bb5fdfb08a35ae8cb8351c5693 228 SUPERFAMILY SSF52540 4 226 3.19E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09025 75e507bb5fdfb08a35ae8cb8351c5693 228 Pfam PF00005 ABC transporter 24 172 1.2E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS01570 312813876b19c89216b4692aa78bac74 669 SMART SM00052 404 650 1.3E-20 T 28-03-2018 IPR001633 EAL domain A6A12_RS01570 312813876b19c89216b4692aa78bac74 669 SMART SM00267 223 393 1.9E-7 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS01570 312813876b19c89216b4692aa78bac74 669 Pfam PF17157 Gammaproteobacterial periplasmic sensor domain 46 141 3.9E-25 T 28-03-2018 IPR033423 Gammaproteobacterial periplasmic sensor domain GAPES4 A6A12_RS01570 312813876b19c89216b4692aa78bac74 669 Pfam PF00990 Diguanylate cyclase, GGDEF domain 236 388 1.1E-16 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS01570 312813876b19c89216b4692aa78bac74 669 Gene3D G3DSA:3.20.20.450 400 654 7.4E-42 T 28-03-2018 IPR001633 EAL domain A6A12_RS01570 312813876b19c89216b4692aa78bac74 669 SUPERFAMILY SSF141868 414 645 1.83E-39 T 28-03-2018 IPR001633 EAL domain A6A12_RS01570 312813876b19c89216b4692aa78bac74 669 Gene3D G3DSA:3.30.70.270 229 399 1.7E-18 T 28-03-2018 A6A12_RS01570 312813876b19c89216b4692aa78bac74 669 Pfam PF00563 EAL domain 440 644 6.0E-43 T 28-03-2018 IPR001633 EAL domain A6A12_RS01570 312813876b19c89216b4692aa78bac74 669 SUPERFAMILY SSF55073 240 393 1.96E-14 T 28-03-2018 IPR029787 Nucleotide cyclase A6A12_RS04670 2c2b0987e2a1f34985a9cacfee21c4ee 235 Gene3D G3DSA:3.90.470.20 28 120 1.1E-12 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A6A12_RS04670 2c2b0987e2a1f34985a9cacfee21c4ee 235 SUPERFAMILY SSF56214 110 225 7.98E-14 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A6A12_RS04670 2c2b0987e2a1f34985a9cacfee21c4ee 235 Gene3D G3DSA:3.90.470.20 121 222 2.6E-10 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A6A12_RS04670 2c2b0987e2a1f34985a9cacfee21c4ee 235 PRINTS PR01399 Enterobactin synthetase component D signature 152 168 2.7E-10 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 A6A12_RS04670 2c2b0987e2a1f34985a9cacfee21c4ee 235 PRINTS PR01399 Enterobactin synthetase component D signature 44 64 2.7E-10 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 A6A12_RS04670 2c2b0987e2a1f34985a9cacfee21c4ee 235 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 111 191 3.3E-12 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 A6A12_RS03430 1642e6514308162d6b6859b28e8c2a15 278 Hamap MF_00795 Copper homeostasis protein CutC [cutC]. 36 278 38.12 T 28-03-2018 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 A6A12_RS03430 1642e6514308162d6b6859b28e8c2a15 278 Pfam PF03932 CutC family 37 236 1.2E-78 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 A6A12_RS03430 1642e6514308162d6b6859b28e8c2a15 278 Gene3D G3DSA:3.20.20.380 35 278 2.6E-85 T 28-03-2018 A6A12_RS03430 1642e6514308162d6b6859b28e8c2a15 278 SUPERFAMILY SSF110395 36 277 3.4E-71 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 A6A12_RS01455 03f6dfaa6d7c123d84ec9fcd9773f8b6 218 Pfam PF13505 Outer membrane protein beta-barrel domain 10 218 5.4E-12 T 28-03-2018 IPR027385 Outer membrane protein beta-barrel A6A12_RS01455 03f6dfaa6d7c123d84ec9fcd9773f8b6 218 TIGRFAM TIGR04219 OMP_w_GlyGly: outer membrane protein 9 218 1.6E-57 T 28-03-2018 IPR026387 Outer membrane protein A6A12_RS03550 d13a99c5dc658921ad177a0ba8fded9f 314 SUPERFAMILY SSF47413 24 95 1.61E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS03550 d13a99c5dc658921ad177a0ba8fded9f 314 Pfam PF13464 Domain of unknown function (DUF4115) 240 313 1.2E-24 T 28-03-2018 IPR025194 Domain of unknown function DUF4115 A6A12_RS03550 d13a99c5dc658921ad177a0ba8fded9f 314 Gene3D G3DSA:1.10.260.40 13 96 6.3E-10 T 28-03-2018 A6A12_RS03550 d13a99c5dc658921ad177a0ba8fded9f 314 Pfam PF13413 Helix-turn-helix domain 29 86 6.6E-18 T 28-03-2018 A6A12_RS12095 cae2285c5291a37a1c1dde921685174f 421 SUPERFAMILY SSF55205 6 417 1.13E-141 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A6A12_RS12095 cae2285c5291a37a1c1dde921685174f 421 Gene3D G3DSA:3.65.10.10 221 419 1.2E-44 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A6A12_RS12095 cae2285c5291a37a1c1dde921685174f 421 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 416 1.3E-182 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS12095 cae2285c5291a37a1c1dde921685174f 421 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 407 2.8E-122 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A6A12_RS12095 cae2285c5291a37a1c1dde921685174f 421 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 43.591 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS12095 cae2285c5291a37a1c1dde921685174f 421 Gene3D G3DSA:3.65.10.10 22 220 1.1E-50 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A6A12_RS08000 a6d53277cb9a9b06289e16d2e929523a 191 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 19 82 1.4E-8 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 A6A12_RS08000 a6d53277cb9a9b06289e16d2e929523a 191 Gene3D G3DSA:1.10.3420.10 8 52 8.3E-4 T 28-03-2018 A6A12_RS08000 a6d53277cb9a9b06289e16d2e929523a 191 Gene3D G3DSA:1.10.3420.10 53 140 2.7E-17 T 28-03-2018 A6A12_RS07585 fe341a39184524aa72ee3a8668611524 512 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 274 303 1.6E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07585 fe341a39184524aa72ee3a8668611524 512 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 377 406 1.6E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07585 fe341a39184524aa72ee3a8668611524 512 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 348 375 1.6E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07585 fe341a39184524aa72ee3a8668611524 512 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 309 477 2.0E-37 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS07585 fe341a39184524aa72ee3a8668611524 512 SMART SM00283 250 511 1.0E-59 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS07585 fe341a39184524aa72ee3a8668611524 512 Gene3D G3DSA:1.10.287.950 279 475 1.6E-51 T 28-03-2018 A6A12_RS07585 fe341a39184524aa72ee3a8668611524 512 Gene3D G3DSA:1.10.287.950 114 278 2.4E-6 T 28-03-2018 A6A12_RS07585 fe341a39184524aa72ee3a8668611524 512 SUPERFAMILY SSF58104 203 512 2.22E-66 T 28-03-2018 A6A12_RS07585 fe341a39184524aa72ee3a8668611524 512 SMART SM00304 181 235 8.0E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS00745 c13926a9ffeee45d232b35541738599d 270 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 77 85 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS00745 c13926a9ffeee45d232b35541738599d 270 SUPERFAMILY SSF53681 114 263 2.4E-34 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS00745 c13926a9ffeee45d232b35541738599d 270 TIGRFAM TIGR00067 glut_race: glutamate racemase 12 228 1.8E-69 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS00745 c13926a9ffeee45d232b35541738599d 270 Gene3D G3DSA:3.40.50.1860 8 130 1.2E-25 T 28-03-2018 A6A12_RS00745 c13926a9ffeee45d232b35541738599d 270 SUPERFAMILY SSF53681 11 111 1.7E-29 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS00745 c13926a9ffeee45d232b35541738599d 270 Pfam PF01177 Asp/Glu/Hydantoin racemase 14 218 4.2E-25 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS00745 c13926a9ffeee45d232b35541738599d 270 Hamap MF_00258 Glutamate racemase [murI]. 10 258 32.43 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS00745 c13926a9ffeee45d232b35541738599d 270 Gene3D G3DSA:3.40.50.1860 131 257 1.3E-25 T 28-03-2018 A6A12_RS05445 2bf1a171eeebb2bcb4999bb47b176696 347 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 72 232 2.3E-54 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 A6A12_RS05445 2bf1a171eeebb2bcb4999bb47b176696 347 Gene3D G3DSA:3.10.290.10 1 64 9.8E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS05445 2bf1a171eeebb2bcb4999bb47b176696 347 Gene3D G3DSA:3.30.70.580 66 148 6.0E-19 T 28-03-2018 A6A12_RS05445 2bf1a171eeebb2bcb4999bb47b176696 347 Gene3D G3DSA:3.30.70.1560 149 218 2.0E-16 T 28-03-2018 A6A12_RS05445 2bf1a171eeebb2bcb4999bb47b176696 347 Pfam PF00849 RNA pseudouridylate synthase 68 185 6.6E-17 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS05445 2bf1a171eeebb2bcb4999bb47b176696 347 SMART SM00363 3 73 1.9E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS05445 2bf1a171eeebb2bcb4999bb47b176696 347 SUPERFAMILY SSF55174 4 96 3.53E-12 T 28-03-2018 A6A12_RS05445 2bf1a171eeebb2bcb4999bb47b176696 347 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 106 120 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 A6A12_RS05445 2bf1a171eeebb2bcb4999bb47b176696 347 Pfam PF01479 S4 domain 4 38 6.2E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS05445 2bf1a171eeebb2bcb4999bb47b176696 347 SUPERFAMILY SSF55120 68 236 1.52E-41 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS11315 a387de57ad82f9abbadfa6f5a87e578d 258 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 11 230 5.6E-81 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A6A12_RS11315 a387de57ad82f9abbadfa6f5a87e578d 258 Hamap MF_00592 Deoxyribose-phosphate aldolase [deoC]. 1 258 52.509 T 28-03-2018 IPR023649 Deoxyribose-phosphate aldolase type II GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 A6A12_RS11315 a387de57ad82f9abbadfa6f5a87e578d 258 PIRSF PIRSF001357 5 253 6.7E-75 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A6A12_RS11315 a387de57ad82f9abbadfa6f5a87e578d 258 Pfam PF01791 DeoC/LacD family aldolase 11 239 2.4E-47 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A6A12_RS11315 a387de57ad82f9abbadfa6f5a87e578d 258 SMART SM01133 10 244 1.4E-74 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A6A12_RS11315 a387de57ad82f9abbadfa6f5a87e578d 258 SUPERFAMILY SSF51569 6 245 4.08E-80 T 28-03-2018 A6A12_RS11315 a387de57ad82f9abbadfa6f5a87e578d 258 Gene3D G3DSA:3.20.20.70 1 257 3.1E-80 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 878 17.422 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 Gene3D G3DSA:3.40.50.300 38 175 0.075 T 28-03-2018 A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 384 538 4.5E-32 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 SUPERFAMILY SSF50447 553 635 1.5E-24 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 SUPERFAMILY SSF52540 374 548 1.06E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 Gene3D G3DSA:3.40.50.300 377 551 9.1E-37 T 28-03-2018 A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 Pfam PF00009 Elongation factor Tu GTP binding domain 385 541 2.3E-32 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 62 100 7.0E-16 T 28-03-2018 IPR013575 Initiation factor 2 associated domain, bacterial A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 50 5.7E-8 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 Pfam PF03144 Elongation factor Tu domain 2 801 867 1.6E-7 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 Gene3D G3DSA:3.30.56.50 4 37 7.1E-10 T 28-03-2018 A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 Pfam PF11987 Translation-initiation factor 2 665 770 1.2E-36 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 SUPERFAMILY SSF52156 658 787 1.44E-38 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 ProSitePatterns PS01176 Initiation factor 2 signature. 831 853 - T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 Gene3D G3DSA:2.40.30.10 781 879 7.4E-31 T 28-03-2018 A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 Gene3D G3DSA:2.40.30.10 553 683 8.1E-32 T 28-03-2018 A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 SUPERFAMILY SSF50447 782 878 1.41E-34 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 SUPERFAMILY SSF46955 3 50 6.77E-12 T 28-03-2018 IPR009061 Putative DNA-binding domain A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 321 880 3.3E-271 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 A6A12_RS02970 1e1c2977c2e442e6c36a136b27a948fd 881 Gene3D G3DSA:3.40.50.10050 684 759 5.6E-26 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A6A12_RS11215 2e490de37a9c6547a5f9b7cff9bbacd2 483 Gene3D G3DSA:3.30.1490.20 281 349 4.7E-13 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A6A12_RS11215 2e490de37a9c6547a5f9b7cff9bbacd2 483 Gene3D G3DSA:3.30.470.20 350 462 3.0E-23 T 28-03-2018 A6A12_RS11215 2e490de37a9c6547a5f9b7cff9bbacd2 483 Pfam PF08443 RimK-like ATP-grasp domain 277 455 3.0E-12 T 28-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 A6A12_RS11215 2e490de37a9c6547a5f9b7cff9bbacd2 483 SUPERFAMILY SSF56059 268 476 8.49E-40 T 28-03-2018 A6A12_RS11215 2e490de37a9c6547a5f9b7cff9bbacd2 483 Pfam PF14401 RimK-like ATPgrasp N-terminal domain 27 167 2.2E-44 T 28-03-2018 IPR025839 RimK-like ATPgrasp N-terminal domain A6A12_RS11215 2e490de37a9c6547a5f9b7cff9bbacd2 483 Gene3D G3DSA:3.40.50.20 170 280 1.3E-24 T 28-03-2018 A6A12_RS01925 d93e2c9da25178bfc5119fb79f3f793e 233 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 80 94 - T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein A6A12_RS01925 d93e2c9da25178bfc5119fb79f3f793e 233 PIRSF PIRSF004848 1 233 8.2E-77 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein A6A12_RS01925 d93e2c9da25178bfc5119fb79f3f793e 233 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 230 1.8E-83 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein A6A12_RS01925 d93e2c9da25178bfc5119fb79f3f793e 233 SUPERFAMILY SSF51419 1 228 9.42E-80 T 28-03-2018 IPR029066 PLP-binding barrel A6A12_RS01925 d93e2c9da25178bfc5119fb79f3f793e 233 Pfam PF01168 Alanine racemase, N-terminal domain 8 230 1.2E-30 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 A6A12_RS01925 d93e2c9da25178bfc5119fb79f3f793e 233 Gene3D G3DSA:3.20.20.10 1 233 8.2E-69 T 28-03-2018 IPR029066 PLP-binding barrel A6A12_RS09490 054e433c3ef797d05dea5bde594ee16b 286 SUPERFAMILY SSF54637 116 283 5.9E-57 T 28-03-2018 IPR029069 HotDog domain A6A12_RS09490 054e433c3ef797d05dea5bde594ee16b 286 Gene3D G3DSA:3.10.129.10 2 116 1.7E-41 T 28-03-2018 A6A12_RS09490 054e433c3ef797d05dea5bde594ee16b 286 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 12 283 5.2E-95 T 28-03-2018 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247 A6A12_RS09490 054e433c3ef797d05dea5bde594ee16b 286 Gene3D G3DSA:3.10.129.10 131 286 4.5E-54 T 28-03-2018 A6A12_RS09490 054e433c3ef797d05dea5bde594ee16b 286 Pfam PF13622 Thioesterase-like superfamily 33 282 6.0E-61 T 28-03-2018 A6A12_RS09490 054e433c3ef797d05dea5bde594ee16b 286 SUPERFAMILY SSF54637 6 114 1.97E-40 T 28-03-2018 IPR029069 HotDog domain A6A12_RS02890 54d41ab5c9d45e59471ff8744312daad 395 SUPERFAMILY SSF52374 6 316 3.5E-97 T 28-03-2018 A6A12_RS02890 54d41ab5c9d45e59471ff8744312daad 395 Pfam PF00579 tRNA synthetases class I (W and Y) 30 317 2.2E-80 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS02890 54d41ab5c9d45e59471ff8744312daad 395 SUPERFAMILY SSF55174 320 394 9.42E-15 T 28-03-2018 A6A12_RS02890 54d41ab5c9d45e59471ff8744312daad 395 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS02890 54d41ab5c9d45e59471ff8744312daad 395 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 9.3E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A6A12_RS02890 54d41ab5c9d45e59471ff8744312daad 395 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 46 68 9.3E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A6A12_RS02890 54d41ab5c9d45e59471ff8744312daad 395 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 178 200 9.3E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A6A12_RS02890 54d41ab5c9d45e59471ff8744312daad 395 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 211 223 9.3E-26 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A6A12_RS02890 54d41ab5c9d45e59471ff8744312daad 395 Gene3D G3DSA:1.10.240.10 219 309 2.8E-27 T 28-03-2018 A6A12_RS02890 54d41ab5c9d45e59471ff8744312daad 395 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 2 394 48.113 T 28-03-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 A6A12_RS02890 54d41ab5c9d45e59471ff8744312daad 395 Gene3D G3DSA:3.40.50.620 1 218 1.6E-60 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS02890 54d41ab5c9d45e59471ff8744312daad 395 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 4 395 1.4E-125 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A6A12_RS02890 54d41ab5c9d45e59471ff8744312daad 395 Gene3D G3DSA:3.10.290.10 310 395 5.3E-19 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS10835 27ae53904f304df3072ee652ca7dd7ce 1159 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1030 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS10835 27ae53904f304df3072ee652ca7dd7ce 1159 Pfam PF14579 Helix-hairpin-helix motif 809 897 6.9E-26 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS10835 27ae53904f304df3072ee652ca7dd7ce 1159 Gene3D G3DSA:3.20.20.140 2 246 1.8E-32 T 28-03-2018 A6A12_RS10835 27ae53904f304df3072ee652ca7dd7ce 1159 SUPERFAMILY SSF89550 5 263 2.75E-11 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A6A12_RS10835 27ae53904f304df3072ee652ca7dd7ce 1159 Gene3D G3DSA:2.40.50.140 972 1073 1.1E-18 T 28-03-2018 A6A12_RS10835 27ae53904f304df3072ee652ca7dd7ce 1159 Gene3D G3DSA:1.10.150.280 777 894 1.5E-9 T 28-03-2018 A6A12_RS10835 27ae53904f304df3072ee652ca7dd7ce 1159 SUPERFAMILY SSF50249 976 1064 5.36E-5 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS10835 27ae53904f304df3072ee652ca7dd7ce 1159 Pfam PF02811 PHP domain 8 172 2.8E-40 T 28-03-2018 IPR004013 PHP domain GO:0003824 A6A12_RS10835 27ae53904f304df3072ee652ca7dd7ce 1159 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 290 735 3.4E-173 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS10835 27ae53904f304df3072ee652ca7dd7ce 1159 SMART SM00481 7 74 3.5E-24 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A6A12_RS10835 27ae53904f304df3072ee652ca7dd7ce 1159 Pfam PF01336 OB-fold nucleic acid binding domain 993 1071 8.1E-10 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A6A12_RS11860 02f17e882fa3359de08286752d058ec2 68 Gene3D G3DSA:3.30.1910.10 1 62 2.9E-30 T 28-03-2018 A6A12_RS11860 02f17e882fa3359de08286752d058ec2 68 Pfam PF06526 Protein of unknown function (DUF1107) 1 63 1.2E-29 T 28-03-2018 IPR009491 Protein of unknown function DUF1107 A6A12_RS11860 02f17e882fa3359de08286752d058ec2 68 ProDom PD055267 YTFK Y0656 CYTOPLASMIC VP2585 VV0426 ESCHERICHIA S4534 VC2473 YPO3527 COLI 1 63 2.0E-28 T 28-03-2018 IPR009491 Protein of unknown function DUF1107 A6A12_RS03515 9c3b5cac4bb78d7cef5286eb9865620a 171 SMART SM00271 1 66 2.3E-7 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS03515 9c3b5cac4bb78d7cef5286eb9865620a 171 SUPERFAMILY SSF46565 1 73 4.97E-16 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS03515 9c3b5cac4bb78d7cef5286eb9865620a 171 Gene3D G3DSA:1.20.1280.20 80 169 1.3E-24 T 28-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 A6A12_RS03515 9c3b5cac4bb78d7cef5286eb9865620a 171 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 1 170 25.383 T 28-03-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 A6A12_RS03515 9c3b5cac4bb78d7cef5286eb9865620a 171 Pfam PF07743 HSCB C-terminal oligomerisation domain 87 163 3.5E-17 T 28-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 A6A12_RS03515 9c3b5cac4bb78d7cef5286eb9865620a 171 Gene3D G3DSA:1.10.287.110 1 76 3.1E-9 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS03515 9c3b5cac4bb78d7cef5286eb9865620a 171 SUPERFAMILY SSF47144 78 170 6.8E-24 T 28-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 A6A12_RS03515 9c3b5cac4bb78d7cef5286eb9865620a 171 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 13 169 1.3E-42 T 28-03-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 A6A12_RS08920 7f8b7192fc5cb888add3f4190a1ed8f6 258 Gene3D G3DSA:3.40.190.10 8 141 1.1E-37 T 28-03-2018 A6A12_RS08920 7f8b7192fc5cb888add3f4190a1ed8f6 258 SUPERFAMILY SSF53850 1 255 1.04E-70 T 28-03-2018 A6A12_RS08920 7f8b7192fc5cb888add3f4190a1ed8f6 258 SMART SM00079 26 253 1.7E-4 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 A6A12_RS08920 7f8b7192fc5cb888add3f4190a1ed8f6 258 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 27 252 6.5E-61 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS08920 7f8b7192fc5cb888add3f4190a1ed8f6 258 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 49 62 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 A6A12_RS08920 7f8b7192fc5cb888add3f4190a1ed8f6 258 SMART SM00062 26 254 1.4E-65 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS08920 7f8b7192fc5cb888add3f4190a1ed8f6 258 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 6 251 2.5E-85 T 28-03-2018 IPR005768 Specific amino acids and opine-binding periplasmic protein, ABC transporter GO:0006810|GO:0030288 A6A12_RS08920 7f8b7192fc5cb888add3f4190a1ed8f6 258 Gene3D G3DSA:3.40.190.10 142 258 1.2E-17 T 28-03-2018 A6A12_RS11500 45139cdb772725b9b830d21e864a272e 305 SUPERFAMILY SSF54211 3 125 1.82E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS11500 45139cdb772725b9b830d21e864a272e 305 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 280 46.109 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A6A12_RS11500 45139cdb772725b9b830d21e864a272e 305 Gene3D G3DSA:3.30.1700.10 129 299 4.0E-69 T 28-03-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A6A12_RS11500 45139cdb772725b9b830d21e864a272e 305 SUPERFAMILY SSF54211 134 278 4.93E-52 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS11500 45139cdb772725b9b830d21e864a272e 305 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 276 2.3E-108 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A6A12_RS11500 45139cdb772725b9b830d21e864a272e 305 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 298 3.9E-142 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A6A12_RS11500 45139cdb772725b9b830d21e864a272e 305 Gene3D G3DSA:3.30.230.20 1 128 9.9E-50 T 28-03-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A6A12_RS04445 b70a20a5964bfb7353a087bbc62bc5e3 322 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 311 3.6E-141 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A6A12_RS04445 b70a20a5964bfb7353a087bbc62bc5e3 322 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 299 2.0E-66 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A6A12_RS04445 b70a20a5964bfb7353a087bbc62bc5e3 322 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 31 49 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A6A12_RS04445 b70a20a5964bfb7353a087bbc62bc5e3 322 TIGRFAM TIGR01136 cysKM: cysteine synthase 10 311 2.4E-134 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A6A12_RS04445 b70a20a5964bfb7353a087bbc62bc5e3 322 Gene3D G3DSA:3.40.50.1100 138 322 4.0E-58 T 28-03-2018 A6A12_RS04445 b70a20a5964bfb7353a087bbc62bc5e3 322 Gene3D G3DSA:3.40.50.1100 40 137 1.5E-31 T 28-03-2018 A6A12_RS04445 b70a20a5964bfb7353a087bbc62bc5e3 322 SUPERFAMILY SSF53686 4 309 1.96E-95 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A6A12_RS08590 c9bc768d1b6f4e1d201ffca6ff53c805 69 SUPERFAMILY SSF47413 3 52 1.66E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS08590 c9bc768d1b6f4e1d201ffca6ff53c805 69 Pfam PF01381 Helix-turn-helix 4 52 3.4E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A6A12_RS08590 c9bc768d1b6f4e1d201ffca6ff53c805 69 SMART SM00530 3 61 1.5E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A6A12_RS08590 c9bc768d1b6f4e1d201ffca6ff53c805 69 Gene3D G3DSA:1.10.260.40 1 69 1.7E-13 T 28-03-2018 A6A12_RS06990 6390a02ae54fed8b977d77140120e787 459 Pfam PF01235 Sodium:alanine symporter family 54 448 1.7E-138 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS06990 6390a02ae54fed8b977d77140120e787 459 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 92 107 - T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS06990 6390a02ae54fed8b977d77140120e787 459 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 441 2.7E-154 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS06990 6390a02ae54fed8b977d77140120e787 459 PRINTS PR00175 Sodium/alanine symporter signature 212 231 1.6E-52 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS06990 6390a02ae54fed8b977d77140120e787 459 PRINTS PR00175 Sodium/alanine symporter signature 184 202 1.6E-52 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS06990 6390a02ae54fed8b977d77140120e787 459 PRINTS PR00175 Sodium/alanine symporter signature 412 432 1.6E-52 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS06990 6390a02ae54fed8b977d77140120e787 459 PRINTS PR00175 Sodium/alanine symporter signature 353 375 1.6E-52 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS06990 6390a02ae54fed8b977d77140120e787 459 PRINTS PR00175 Sodium/alanine symporter signature 92 114 1.6E-52 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS06990 6390a02ae54fed8b977d77140120e787 459 PRINTS PR00175 Sodium/alanine symporter signature 307 325 1.6E-52 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS11805 b882a9fb96b6d05e7c6ce79b211d3417 298 ProSitePatterns PS00501 Signal peptidases I serine active site. 88 95 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 A6A12_RS11805 b882a9fb96b6d05e7c6ce79b211d3417 298 SUPERFAMILY SSF51306 77 296 5.58E-70 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A6A12_RS11805 b882a9fb96b6d05e7c6ce79b211d3417 298 Pfam PF10502 Signal peptidase, peptidase S26 208 268 6.1E-8 T 28-03-2018 IPR019533 Peptidase S26 A6A12_RS11805 b882a9fb96b6d05e7c6ce79b211d3417 298 Gene3D G3DSA:2.10.109.10 75 294 4.1E-55 T 28-03-2018 A6A12_RS11805 b882a9fb96b6d05e7c6ce79b211d3417 298 Pfam PF00717 Peptidase S24-like 85 161 8.9E-22 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A6A12_RS11805 b882a9fb96b6d05e7c6ce79b211d3417 298 ProSitePatterns PS00761 Signal peptidases I signature 3. 236 249 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 A6A12_RS11805 b882a9fb96b6d05e7c6ce79b211d3417 298 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 143 155 9.2E-27 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A6A12_RS11805 b882a9fb96b6d05e7c6ce79b211d3417 298 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 231 250 9.2E-27 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A6A12_RS11805 b882a9fb96b6d05e7c6ce79b211d3417 298 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 79 95 9.2E-27 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A6A12_RS11805 b882a9fb96b6d05e7c6ce79b211d3417 298 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 65 271 1.4E-47 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 A6A12_RS11805 b882a9fb96b6d05e7c6ce79b211d3417 298 ProSitePatterns PS00760 Signal peptidases I lysine active site. 145 157 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 A6A12_RS00845 c8f9ba32ac3d24b16ed109c8e9d65cde 291 Hamap MF_00117 33 kDa chaperonin [hslO]. 3 283 32.241 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A6A12_RS00845 c8f9ba32ac3d24b16ed109c8e9d65cde 291 Gene3D G3DSA:1.10.287.480 180 224 2.5E-18 T 28-03-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain A6A12_RS00845 c8f9ba32ac3d24b16ed109c8e9d65cde 291 PIRSF PIRSF005261 1 284 2.1E-70 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A6A12_RS00845 c8f9ba32ac3d24b16ed109c8e9d65cde 291 Pfam PF01430 Hsp33 protein 6 271 2.2E-79 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 A6A12_RS00845 c8f9ba32ac3d24b16ed109c8e9d65cde 291 Gene3D G3DSA:3.90.1280.10 225 280 3.9E-20 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 A6A12_RS00845 c8f9ba32ac3d24b16ed109c8e9d65cde 291 Gene3D G3DSA:3.55.30.10 1 175 1.7E-58 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 A6A12_RS00845 c8f9ba32ac3d24b16ed109c8e9d65cde 291 SUPERFAMILY SSF64397 4 231 1.7E-75 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 A6A12_RS00845 c8f9ba32ac3d24b16ed109c8e9d65cde 291 SUPERFAMILY SSF118352 223 281 3.92E-18 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 A6A12_RS05050 6b75c92e951d91c9c73f0929728c0bb9 93 Hamap MF_01866 Protein YcgL [ycgL]. 1 87 27.032 T 28-03-2018 IPR027354 YcgL domain A6A12_RS05050 6b75c92e951d91c9c73f0929728c0bb9 93 SUPERFAMILY SSF160191 1 92 1.07E-36 T 28-03-2018 A6A12_RS05050 6b75c92e951d91c9c73f0929728c0bb9 93 Pfam PF05166 YcgL domain 3 74 4.8E-31 T 28-03-2018 IPR027354 YcgL domain A6A12_RS05050 6b75c92e951d91c9c73f0929728c0bb9 93 ProDom PD030374 YCGL UNCHARACTERIZED SIMILAR BACTERIA HI1446 Y2231 HYDROLASE CYTOPLASMIC YPO2080 SO2575 1 69 2.0E-29 T 28-03-2018 IPR027354 YcgL domain A6A12_RS12575 bad301a1e2e726e85c7a9c2fbfecc3d4 335 Gene3D G3DSA:3.40.50.1820 26 317 8.7E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS12575 bad301a1e2e726e85c7a9c2fbfecc3d4 335 Pfam PF00561 alpha/beta hydrolase fold 63 302 7.0E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A6A12_RS12575 bad301a1e2e726e85c7a9c2fbfecc3d4 335 PIRSF PIRSF005211 1 335 9.8E-105 T 28-03-2018 IPR012020 AB hydrolase 4 family A6A12_RS12575 bad301a1e2e726e85c7a9c2fbfecc3d4 335 SUPERFAMILY SSF53474 32 190 1.8E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS12575 bad301a1e2e726e85c7a9c2fbfecc3d4 335 SUPERFAMILY SSF53474 223 301 1.8E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS11415 af078fad8c88b7a976779ad1e263b0b1 489 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 146 459 1.5E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS11415 af078fad8c88b7a976779ad1e263b0b1 489 SUPERFAMILY SSF46548 2 155 7.85E-35 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A6A12_RS11415 af078fad8c88b7a976779ad1e263b0b1 489 Gene3D G3DSA:3.50.50.60 242 327 7.1E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS11415 af078fad8c88b7a976779ad1e263b0b1 489 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 1.8E-23 T 28-03-2018 A6A12_RS11415 af078fad8c88b7a976779ad1e263b0b1 489 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 1.8E-23 T 28-03-2018 A6A12_RS11415 af078fad8c88b7a976779ad1e263b0b1 489 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 1.8E-23 T 28-03-2018 A6A12_RS11415 af078fad8c88b7a976779ad1e263b0b1 489 PRINTS PR00419 Adrenodoxin reductase family signature 286 300 1.8E-23 T 28-03-2018 A6A12_RS11415 af078fad8c88b7a976779ad1e263b0b1 489 Gene3D G3DSA:1.10.1060.10 7 138 1.7E-37 T 28-03-2018 A6A12_RS11415 af078fad8c88b7a976779ad1e263b0b1 489 Gene3D G3DSA:3.40.50.720 139 241 2.2E-18 T 28-03-2018 A6A12_RS11415 af078fad8c88b7a976779ad1e263b0b1 489 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 478 3.7E-194 T 28-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 A6A12_RS11415 af078fad8c88b7a976779ad1e263b0b1 489 SUPERFAMILY SSF51971 143 407 1.65E-63 T 28-03-2018 A6A12_RS11415 af078fad8c88b7a976779ad1e263b0b1 489 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 38 131 3.0E-24 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A6A12_RS11415 af078fad8c88b7a976779ad1e263b0b1 489 SUPERFAMILY SSF51971 389 479 3.88E-8 T 28-03-2018 A6A12_RS11415 af078fad8c88b7a976779ad1e263b0b1 489 Gene3D G3DSA:3.50.50.60 333 474 2.8E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS13955 75bdc45ac92aed066c10872fed32730e 571 SMART SM00382 32 231 4.2E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS13955 75bdc45ac92aed066c10872fed32730e 571 SMART SM00382 338 534 1.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS13955 75bdc45ac92aed066c10872fed32730e 571 Gene3D G3DSA:3.40.50.300 299 567 2.6E-72 T 28-03-2018 A6A12_RS13955 75bdc45ac92aed066c10872fed32730e 571 Gene3D G3DSA:3.40.50.300 1 286 2.2E-69 T 28-03-2018 A6A12_RS13955 75bdc45ac92aed066c10872fed32730e 571 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS13955 75bdc45ac92aed066c10872fed32730e 571 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 270 9.3E-6 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A6A12_RS13955 75bdc45ac92aed066c10872fed32730e 571 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 534 563 9.0E-4 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A6A12_RS13955 75bdc45ac92aed066c10872fed32730e 571 ProSitePatterns PS00211 ABC transporters family signature. 455 469 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS13955 75bdc45ac92aed066c10872fed32730e 571 SUPERFAMILY SSF52540 303 553 6.58E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13955 75bdc45ac92aed066c10872fed32730e 571 SUPERFAMILY SSF52540 3 253 1.33E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13955 75bdc45ac92aed066c10872fed32730e 571 Pfam PF00005 ABC transporter 24 181 4.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS13955 75bdc45ac92aed066c10872fed32730e 571 Pfam PF00005 ABC transporter 330 483 1.1E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS01540 42ae45cc958ac55b251f1a974deafd7f 458 SUPERFAMILY SSF158791 15 136 3.92E-19 T 28-03-2018 A6A12_RS01540 42ae45cc958ac55b251f1a974deafd7f 458 TIGRFAM TIGR00400 mgtE: magnesium transporter 28 452 4.5E-110 T 28-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 A6A12_RS01540 42ae45cc958ac55b251f1a974deafd7f 458 SMART SM00924 31 140 6.5E-18 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain A6A12_RS01540 42ae45cc958ac55b251f1a974deafd7f 458 Pfam PF01769 Divalent cation transporter 326 445 1.2E-26 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A6A12_RS01540 42ae45cc958ac55b251f1a974deafd7f 458 SMART SM00116 211 259 0.016 T 28-03-2018 IPR000644 CBS domain A6A12_RS01540 42ae45cc958ac55b251f1a974deafd7f 458 SMART SM00116 147 200 0.0021 T 28-03-2018 IPR000644 CBS domain A6A12_RS01540 42ae45cc958ac55b251f1a974deafd7f 458 SUPERFAMILY SSF161093 282 452 3.01E-49 T 28-03-2018 A6A12_RS01540 42ae45cc958ac55b251f1a974deafd7f 458 SUPERFAMILY SSF54631 139 270 4.3E-31 T 28-03-2018 A6A12_RS01540 42ae45cc958ac55b251f1a974deafd7f 458 Gene3D G3DSA:1.25.60.10 4 128 1.7E-10 T 28-03-2018 A6A12_RS01540 42ae45cc958ac55b251f1a974deafd7f 458 Pfam PF03448 MgtE intracellular N domain 33 137 3.1E-17 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain A6A12_RS01540 42ae45cc958ac55b251f1a974deafd7f 458 Gene3D G3DSA:3.10.580.10 129 201 1.1E-10 T 28-03-2018 A6A12_RS01540 42ae45cc958ac55b251f1a974deafd7f 458 Gene3D G3DSA:3.10.580.10 202 282 7.2E-10 T 28-03-2018 A6A12_RS01540 42ae45cc958ac55b251f1a974deafd7f 458 Pfam PF00571 CBS domain 140 198 2.5E-9 T 28-03-2018 IPR000644 CBS domain A6A12_RS01540 42ae45cc958ac55b251f1a974deafd7f 458 Pfam PF00571 CBS domain 204 256 3.2E-7 T 28-03-2018 IPR000644 CBS domain A6A12_RS01540 42ae45cc958ac55b251f1a974deafd7f 458 Gene3D G3DSA:1.10.357.20 283 454 1.8E-38 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A6A12_RS08880 9fc1221a5cd3fab92f0ad6c4962cbb12 691 SUPERFAMILY SSF52540 507 610 6.02E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS08880 9fc1221a5cd3fab92f0ad6c4962cbb12 691 SUPERFAMILY SSF52540 243 265 6.02E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS08880 9fc1221a5cd3fab92f0ad6c4962cbb12 691 SUPERFAMILY SSF52540 641 665 6.02E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS08880 9fc1221a5cd3fab92f0ad6c4962cbb12 691 Pfam PF13307 Helicase C-terminal domain 526 684 3.4E-34 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A6A12_RS08880 9fc1221a5cd3fab92f0ad6c4962cbb12 691 SMART SM00491 535 671 1.1E-25 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A6A12_RS08880 9fc1221a5cd3fab92f0ad6c4962cbb12 691 Pfam PF06733 DEAD_2 198 263 6.1E-6 T 28-03-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 A6A12_RS08880 9fc1221a5cd3fab92f0ad6c4962cbb12 691 SUPERFAMILY SSF52540 207 263 2.37E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS08880 9fc1221a5cd3fab92f0ad6c4962cbb12 691 SUPERFAMILY SSF52540 630 666 2.37E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS08880 9fc1221a5cd3fab92f0ad6c4962cbb12 691 SUPERFAMILY SSF52540 18 123 2.37E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS08880 9fc1221a5cd3fab92f0ad6c4962cbb12 691 Gene3D G3DSA:3.40.50.300 498 681 6.2E-10 T 28-03-2018 A6A12_RS08880 9fc1221a5cd3fab92f0ad6c4962cbb12 691 Gene3D G3DSA:3.40.50.300 23 480 2.3E-21 T 28-03-2018 A6A12_RS08935 cb565a422008d41139254f4cae10fdbf 513 Pfam PF11840 Protein of unknown function (DUF3360) 9 513 2.9E-264 T 28-03-2018 IPR021794 Protein of unknown function DUF3360 A6A12_RS03035 0e9e56997692e550e08095cca0b5b892 134 Pfam PF03603 DNA polymerase III psi subunit 3 131 4.5E-37 T 28-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS03035 0e9e56997692e550e08095cca0b5b892 134 SUPERFAMILY SSF102220 33 133 2.62E-25 T 28-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS03035 0e9e56997692e550e08095cca0b5b892 134 ProDom PD032475 DNA POLYMERASE PSI SUBUNIT III TRANSFERASE NUCLEOTIDYLTRANSFERASE III 3D-STRUCTURE DNA-DIRECTED 36 129 8.0E-4 T 28-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS03035 0e9e56997692e550e08095cca0b5b892 134 Gene3D G3DSA:3.40.50.10220 37 133 1.9E-26 T 28-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS03035 0e9e56997692e550e08095cca0b5b892 134 PIRSF PIRSF029225 2 134 3.5E-39 T 28-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS09690 4f161f9caee4c9a6aa0c78ec6cb69fd4 307 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 290 7.0E-123 T 28-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A6A12_RS09690 4f161f9caee4c9a6aa0c78ec6cb69fd4 307 Gene3D G3DSA:3.40.366.10 1 184 3.7E-53 T 28-03-2018 A6A12_RS09690 4f161f9caee4c9a6aa0c78ec6cb69fd4 307 SUPERFAMILY SSF55048 130 197 1.83E-17 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 A6A12_RS09690 4f161f9caee4c9a6aa0c78ec6cb69fd4 307 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 306 1.0E-46 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain A6A12_RS09690 4f161f9caee4c9a6aa0c78ec6cb69fd4 307 Pfam PF00698 Acyl transferase domain 7 298 9.2E-41 T 28-03-2018 IPR014043 Acyl transferase A6A12_RS09690 4f161f9caee4c9a6aa0c78ec6cb69fd4 307 SUPERFAMILY SSF52151 190 305 3.66E-82 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A6A12_RS09690 4f161f9caee4c9a6aa0c78ec6cb69fd4 307 SUPERFAMILY SSF52151 4 122 3.66E-82 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A6A12_RS09690 4f161f9caee4c9a6aa0c78ec6cb69fd4 307 Gene3D G3DSA:3.40.366.10 185 307 3.0E-30 T 28-03-2018 A6A12_RS09690 4f161f9caee4c9a6aa0c78ec6cb69fd4 307 PIRSF PIRSF000446 1 307 3.9E-134 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 A6A12_RS11615 d6d942d1b335119c19f6a7d315b4c0c1 421 SUPERFAMILY SSF81342 248 296 2.04E-92 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A6A12_RS11615 d6d942d1b335119c19f6a7d315b4c0c1 421 SUPERFAMILY SSF81342 6 221 2.04E-92 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A6A12_RS11615 d6d942d1b335119c19f6a7d315b4c0c1 421 PIRSF PIRSF038885 1 421 7.5E-153 T 28-03-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 A6A12_RS11615 d6d942d1b335119c19f6a7d315b4c0c1 421 Pfam PF00033 Cytochrome b/b6/petB 23 211 6.7E-66 T 28-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A6A12_RS11615 d6d942d1b335119c19f6a7d315b4c0c1 421 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 295 396 9.8E-40 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A6A12_RS11615 d6d942d1b335119c19f6a7d315b4c0c1 421 SUPERFAMILY SSF81648 297 412 3.71E-33 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 A6A12_RS11615 d6d942d1b335119c19f6a7d315b4c0c1 421 Gene3D G3DSA:1.20.810.10 6 416 1.1E-158 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 A6A12_RS06430 00b1f2702d5116a8487bcfeb048ef681 160 Pfam PF00583 Acetyltransferase (GNAT) family 24 146 8.5E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A6A12_RS06430 00b1f2702d5116a8487bcfeb048ef681 160 Gene3D G3DSA:3.40.630.30 1 153 2.2E-27 T 28-03-2018 A6A12_RS06430 00b1f2702d5116a8487bcfeb048ef681 160 SUPERFAMILY SSF55729 4 147 2.29E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS08855 7aa60537b7899d4a0af0f6b9951494e0 164 Gene3D G3DSA:2.40.100.10 1 164 1.5E-48 T 28-03-2018 IPR029000 Cyclophilin-like domain A6A12_RS08855 7aa60537b7899d4a0af0f6b9951494e0 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 41 53 1.2E-10 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A6A12_RS08855 7aa60537b7899d4a0af0f6b9951494e0 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 15 30 1.2E-10 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A6A12_RS08855 7aa60537b7899d4a0af0f6b9951494e0 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 118 133 1.2E-10 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A6A12_RS08855 7aa60537b7899d4a0af0f6b9951494e0 164 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 36 53 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 A6A12_RS08855 7aa60537b7899d4a0af0f6b9951494e0 164 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 2 155 5.8E-46 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 A6A12_RS08855 7aa60537b7899d4a0af0f6b9951494e0 164 SUPERFAMILY SSF50891 1 162 9.79E-57 T 28-03-2018 IPR029000 Cyclophilin-like domain A6A12_RS08855 7aa60537b7899d4a0af0f6b9951494e0 164 PIRSF PIRSF001467 1 161 6.1E-28 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 A6A12_RS11835 94ec4b9c8381042fa17a3fe603f6d6fc 535 SUPERFAMILY SSF56425 238 353 2.39E-41 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS11835 94ec4b9c8381042fa17a3fe603f6d6fc 535 Pfam PF00890 FAD binding domain 10 392 1.4E-102 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS11835 94ec4b9c8381042fa17a3fe603f6d6fc 535 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 9 520 1.2E-210 T 28-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 A6A12_RS11835 94ec4b9c8381042fa17a3fe603f6d6fc 535 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 1.5E-5 T 28-03-2018 A6A12_RS11835 94ec4b9c8381042fa17a3fe603f6d6fc 535 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 370 377 1.5E-5 T 28-03-2018 A6A12_RS11835 94ec4b9c8381042fa17a3fe603f6d6fc 535 Gene3D G3DSA:1.20.58.100 438 522 1.1E-28 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS11835 94ec4b9c8381042fa17a3fe603f6d6fc 535 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 7.1E-9 T 28-03-2018 A6A12_RS11835 94ec4b9c8381042fa17a3fe603f6d6fc 535 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 7.1E-9 T 28-03-2018 A6A12_RS11835 94ec4b9c8381042fa17a3fe603f6d6fc 535 SUPERFAMILY SSF46977 425 525 1.96E-32 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS11835 94ec4b9c8381042fa17a3fe603f6d6fc 535 SUPERFAMILY SSF51905 9 255 5.58E-74 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS11835 94ec4b9c8381042fa17a3fe603f6d6fc 535 SUPERFAMILY SSF51905 356 447 5.58E-74 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS11835 94ec4b9c8381042fa17a3fe603f6d6fc 535 Gene3D G3DSA:3.50.50.60 2 437 1.6E-69 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS11835 94ec4b9c8381042fa17a3fe603f6d6fc 535 Pfam PF02910 Fumarate reductase flavoprotein C-term 441 521 4.6E-14 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS11835 94ec4b9c8381042fa17a3fe603f6d6fc 535 PIRSF PIRSF000171 336 532 5.8E-12 T 28-03-2018 A6A12_RS11835 94ec4b9c8381042fa17a3fe603f6d6fc 535 PIRSF PIRSF000171 1 248 1.7E-27 T 28-03-2018 A6A12_RS09400 a7aa650eeae164b2505656a0b962d33c 552 Gene3D G3DSA:3.30.70.1450 190 279 8.9E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS09400 a7aa650eeae164b2505656a0b962d33c 552 Pfam PF02080 TrkA-C domain 294 355 1.5E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS09400 a7aa650eeae164b2505656a0b962d33c 552 Hamap MF_01016 Putative transport protein YidE [yidE]. 1 552 54.878 T 28-03-2018 IPR023018 Transport protein YidE, putative A6A12_RS09400 a7aa650eeae164b2505656a0b962d33c 552 Pfam PF06826 Predicted Permease Membrane Region 11 179 2.1E-42 T 28-03-2018 IPR006512 YidE/YbjL duplication A6A12_RS09400 a7aa650eeae164b2505656a0b962d33c 552 Pfam PF06826 Predicted Permease Membrane Region 374 546 7.8E-47 T 28-03-2018 IPR006512 YidE/YbjL duplication A6A12_RS09400 a7aa650eeae164b2505656a0b962d33c 552 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 16 166 4.3E-37 T 28-03-2018 IPR006512 YidE/YbjL duplication A6A12_RS09400 a7aa650eeae164b2505656a0b962d33c 552 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 379 533 2.9E-47 T 28-03-2018 IPR006512 YidE/YbjL duplication A6A12_RS09400 a7aa650eeae164b2505656a0b962d33c 552 Gene3D G3DSA:3.30.70.1450 280 366 4.5E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS09400 a7aa650eeae164b2505656a0b962d33c 552 SUPERFAMILY SSF116726 204 271 3.4E-7 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS09400 a7aa650eeae164b2505656a0b962d33c 552 SUPERFAMILY SSF116726 278 358 3.79E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A6A12_RS04850 6d9b1e07652388ca7c8239f91f70ef1d 241 Pfam PF11859 Protein of unknown function (DUF3379) 1 236 3.2E-85 T 28-03-2018 IPR021806 Protein of unknown function DUF3379 A6A12_RS12080 5c20108cbd1274945bb78cf895b5a3d2 183 SMART SM00989 118 178 7.3E-6 T 28-03-2018 IPR004096 4-vinyl reductase, 4VR A6A12_RS12080 5c20108cbd1274945bb78cf895b5a3d2 183 Gene3D G3DSA:3.90.1520.10 1 183 1.4E-38 T 28-03-2018 A6A12_RS12080 5c20108cbd1274945bb78cf895b5a3d2 183 Pfam PF07700 Haem-NO-binding 3 161 1.4E-37 T 28-03-2018 IPR011644 Heme-NO binding GO:0020037 KEGG: 00230+4.6.1.2|Reactome: R-HSA-392154 A6A12_RS12080 5c20108cbd1274945bb78cf895b5a3d2 183 SUPERFAMILY SSF111126 1 181 2.07E-50 T 28-03-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain A6A12_RS13470 9d6bd92008d3ddb9e8ca4d368e0db9fa 291 Pfam PF00535 Glycosyl transferase family 2 26 152 1.4E-14 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A6A12_RS13470 9d6bd92008d3ddb9e8ca4d368e0db9fa 291 Gene3D G3DSA:3.90.550.10 18 291 1.3E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13470 9d6bd92008d3ddb9e8ca4d368e0db9fa 291 SUPERFAMILY SSF53448 196 289 5.25E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13470 9d6bd92008d3ddb9e8ca4d368e0db9fa 291 SUPERFAMILY SSF53448 21 144 5.25E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13470 9d6bd92008d3ddb9e8ca4d368e0db9fa 291 Pfam PF02709 N-terminal domain of galactosyltransferase 192 255 1.6E-11 T 28-03-2018 IPR027791 Galactosyltransferase, C-terminal Reactome: R-HSA-2022854|Reactome: R-HSA-975577 A6A12_RS13145 0511c18c2641e19dd18c134d9f6bb5ab 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 7.1E-33 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS13145 0511c18c2641e19dd18c134d9f6bb5ab 90 Gene3D G3DSA:4.10.520.10 1 90 7.9E-34 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A6A12_RS13145 0511c18c2641e19dd18c134d9f6bb5ab 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 4.6E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS13145 0511c18c2641e19dd18c134d9f6bb5ab 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 4.6E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS13145 0511c18c2641e19dd18c134d9f6bb5ab 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 4.6E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS13145 0511c18c2641e19dd18c134d9f6bb5ab 90 SUPERFAMILY SSF47729 1 90 2.06E-32 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A6A12_RS13145 0511c18c2641e19dd18c134d9f6bb5ab 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A6A12_RS13145 0511c18c2641e19dd18c134d9f6bb5ab 90 SMART SM00411 1 90 1.7E-44 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS06545 4180f3f33427a7a691d3dc8786ed7d5e 296 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 83 280 6.6E-21 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A6A12_RS06545 4180f3f33427a7a691d3dc8786ed7d5e 296 SUPERFAMILY SSF51621 80 273 1.71E-35 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A6A12_RS06545 4180f3f33427a7a691d3dc8786ed7d5e 296 Gene3D G3DSA:3.20.20.60 38 294 6.1E-39 T 28-03-2018 A6A12_RS13150 ac9fb1f85b20a402c25cd7b999d92006 351 Pfam PF00571 CBS domain 263 313 1.9E-6 T 28-03-2018 IPR000644 CBS domain A6A12_RS13150 ac9fb1f85b20a402c25cd7b999d92006 351 Gene3D G3DSA:3.20.20.70 138 340 9.5E-27 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS13150 ac9fb1f85b20a402c25cd7b999d92006 351 SUPERFAMILY SSF54631 181 315 6.42E-23 T 28-03-2018 A6A12_RS13150 ac9fb1f85b20a402c25cd7b999d92006 351 Pfam PF01595 Domain of unknown function DUF21 8 175 8.6E-30 T 28-03-2018 IPR002550 Domain of unknown function DUF21 A6A12_RS09660 2590eaae4696841572350c64f24277ce 214 ProSitePatterns PS01331 Thymidylate kinase signature. 95 107 - T 28-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A6A12_RS09660 2590eaae4696841572350c64f24277ce 214 SUPERFAMILY SSF52540 1 210 5.57E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09660 2590eaae4696841572350c64f24277ce 214 Pfam PF02223 Thymidylate kinase 8 195 1.1E-52 T 28-03-2018 A6A12_RS09660 2590eaae4696841572350c64f24277ce 214 Hamap MF_00165 Thymidylate kinase [tmk]. 4 206 26.853 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A6A12_RS09660 2590eaae4696841572350c64f24277ce 214 Gene3D G3DSA:3.40.50.300 1 213 1.6E-47 T 28-03-2018 A6A12_RS09660 2590eaae4696841572350c64f24277ce 214 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 195 1.3E-58 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A6A12_RS14335 dfaafa4cd46b9b2e256544a945f9658c 401 Pfam PF07690 Major Facilitator Superfamily 13 340 3.8E-39 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A6A12_RS14335 dfaafa4cd46b9b2e256544a945f9658c 401 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 4 369 2.8E-86 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 A6A12_RS14335 dfaafa4cd46b9b2e256544a945f9658c 401 SUPERFAMILY SSF103473 5 377 3.4E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain A6A12_RS14335 dfaafa4cd46b9b2e256544a945f9658c 401 Gene3D G3DSA:1.20.1250.20 5 193 2.2E-26 T 28-03-2018 A6A12_RS14335 dfaafa4cd46b9b2e256544a945f9658c 401 Gene3D G3DSA:1.20.1250.20 194 383 2.9E-16 T 28-03-2018 A6A12_RS02055 06c8c1823435035a6f104391218c6688 585 Pfam PF13444 Acetyltransferase (GNAT) domain 330 431 4.8E-21 T 28-03-2018 A6A12_RS02055 06c8c1823435035a6f104391218c6688 585 SMART SM00563 75 199 6.3E-7 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A6A12_RS02055 06c8c1823435035a6f104391218c6688 585 Pfam PF01553 Acyltransferase 67 196 1.1E-4 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A6A12_RS02055 06c8c1823435035a6f104391218c6688 585 SUPERFAMILY SSF55729 313 480 1.96E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS02055 06c8c1823435035a6f104391218c6688 585 Gene3D G3DSA:3.40.630.30 311 485 2.2E-20 T 28-03-2018 A6A12_RS02055 06c8c1823435035a6f104391218c6688 585 Gene3D G3DSA:3.40.1130.10 28 276 1.1E-21 T 28-03-2018 A6A12_RS02055 06c8c1823435035a6f104391218c6688 585 SUPERFAMILY SSF69593 56 248 9.55E-7 T 28-03-2018 A6A12_RS01015 ef3ca1ada607745c8fa12d9f10314b95 706 Pfam PF13291 ACT domain 627 703 2.1E-13 T 28-03-2018 IPR002912 ACT domain A6A12_RS01015 ef3ca1ada607745c8fa12d9f10314b95 706 Pfam PF04607 Region found in RelA / SpoT proteins 235 345 2.8E-34 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 A6A12_RS01015 ef3ca1ada607745c8fa12d9f10314b95 706 SUPERFAMILY SSF109604 3 190 5.02E-74 T 28-03-2018 A6A12_RS01015 ef3ca1ada607745c8fa12d9f10314b95 706 SUPERFAMILY SSF81271 376 448 3.43E-20 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A6A12_RS01015 ef3ca1ada607745c8fa12d9f10314b95 706 Pfam PF13328 HD domain 28 175 1.0E-52 T 28-03-2018 IPR003607 HD/PDEase domain A6A12_RS01015 ef3ca1ada607745c8fa12d9f10314b95 706 Gene3D G3DSA:3.10.20.30 383 458 2.3E-20 T 28-03-2018 IPR012675 Beta-grasp domain A6A12_RS01015 ef3ca1ada607745c8fa12d9f10314b95 706 SUPERFAMILY SSF55021 631 703 9.92E-8 T 28-03-2018 A6A12_RS01015 ef3ca1ada607745c8fa12d9f10314b95 706 Gene3D G3DSA:3.30.460.10 192 325 4.3E-39 T 28-03-2018 A6A12_RS01015 ef3ca1ada607745c8fa12d9f10314b95 706 SMART SM00471 41 153 1.1E-9 T 28-03-2018 IPR003607 HD/PDEase domain A6A12_RS01015 ef3ca1ada607745c8fa12d9f10314b95 706 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 27 703 1.9E-267 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 A6A12_RS01015 ef3ca1ada607745c8fa12d9f10314b95 706 SUPERFAMILY SSF81301 180 393 6.21E-59 T 28-03-2018 A6A12_RS01015 ef3ca1ada607745c8fa12d9f10314b95 706 Gene3D G3DSA:3.30.70.260 626 706 1.7E-9 T 28-03-2018 A6A12_RS01015 ef3ca1ada607745c8fa12d9f10314b95 706 Pfam PF02824 TGS domain 389 447 2.5E-18 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A6A12_RS01015 ef3ca1ada607745c8fa12d9f10314b95 706 SMART SM00954 235 345 1.7E-58 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 SUPERFAMILY SSF50465 332 434 2.73E-27 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 SUPERFAMILY SSF50447 243 324 4.2E-23 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 Pfam PF00009 Elongation factor Tu GTP binding domain 26 231 1.5E-45 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 PRINTS PR00315 GTP-binding elongation factor signature 125 136 6.8E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 PRINTS PR00315 GTP-binding elongation factor signature 162 171 6.8E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 PRINTS PR00315 GTP-binding elongation factor signature 109 119 6.8E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 PRINTS PR00315 GTP-binding elongation factor signature 89 97 6.8E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 PRINTS PR00315 GTP-binding elongation factor signature 28 41 6.8E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 Gene3D G3DSA:2.40.30.10 331 435 2.0E-15 T 28-03-2018 A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 Gene3D G3DSA:2.40.30.10 239 327 6.5E-22 T 28-03-2018 A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 Gene3D G3DSA:3.40.50.300 4 238 2.9E-43 T 28-03-2018 A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 82 97 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 SUPERFAMILY SSF52540 19 235 1.06E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 18 474 53.899 T 28-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 27 433 1.2E-199 T 28-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A6A12_RS12300 35194c2c1ebf85adb399ae86702b1dd0 476 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 33 217 1.0E-13 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A6A12_RS06850 cbe161813aa9ac077072678226cfd6f0 303 SUPERFAMILY SSF53067 1 300 6.49E-57 T 28-03-2018 A6A12_RS06850 cbe161813aa9ac077072678226cfd6f0 303 Hamap MF_01271 N-acetyl-D-glucosamine kinase [nagK]. 1 303 63.466 T 28-03-2018 IPR023505 N-acetyl-D-glucosamine kinase GO:0045127 KEGG: 00520+2.7.1.59|MetaCyc: PWY-6517|MetaCyc: PWY-6906 A6A12_RS06850 cbe161813aa9ac077072678226cfd6f0 303 Pfam PF00480 ROK family 2 300 5.0E-72 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A6A12_RS06850 cbe161813aa9ac077072678226cfd6f0 303 Gene3D G3DSA:3.30.420.40 115 303 8.5E-44 T 28-03-2018 A6A12_RS06850 cbe161813aa9ac077072678226cfd6f0 303 Gene3D G3DSA:3.30.420.40 1 114 9.9E-22 T 28-03-2018 A6A12_RS06850 cbe161813aa9ac077072678226cfd6f0 303 ProSitePatterns PS01125 ROK family signature. 130 157 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 A6A12_RS03540 2fd5e0dccf366a54d97f8b2d8de30ffb 141 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 28-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A6A12_RS03540 2fd5e0dccf366a54d97f8b2d8de30ffb 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 36.305 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A6A12_RS03540 2fd5e0dccf366a54d97f8b2d8de30ffb 141 SMART SM00562 3 140 1.8E-90 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A6A12_RS03540 2fd5e0dccf366a54d97f8b2d8de30ffb 141 Gene3D G3DSA:3.30.70.141 57 140 2.5E-35 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A6A12_RS03540 2fd5e0dccf366a54d97f8b2d8de30ffb 141 Gene3D G3DSA:3.30.70.141 1 56 2.8E-19 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A6A12_RS03540 2fd5e0dccf366a54d97f8b2d8de30ffb 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 5.7E-39 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A6A12_RS03540 2fd5e0dccf366a54d97f8b2d8de30ffb 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 5.7E-39 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A6A12_RS03540 2fd5e0dccf366a54d97f8b2d8de30ffb 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 5.7E-39 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A6A12_RS03540 2fd5e0dccf366a54d97f8b2d8de30ffb 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 5.7E-39 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A6A12_RS03540 2fd5e0dccf366a54d97f8b2d8de30ffb 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 5.7E-39 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A6A12_RS03540 2fd5e0dccf366a54d97f8b2d8de30ffb 141 SUPERFAMILY SSF54919 1 140 3.4E-61 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A6A12_RS03540 2fd5e0dccf366a54d97f8b2d8de30ffb 141 Pfam PF00334 Nucleoside diphosphate kinase 4 138 1.2E-58 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A6A12_RS13310 768a63c16d33874db8f33ee1e4a282e1 371 Gene3D G3DSA:3.40.640.10 1 245 1.7E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS13310 768a63c16d33874db8f33ee1e4a282e1 371 Gene3D G3DSA:3.90.1150.10 246 371 1.7E-38 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS13310 768a63c16d33874db8f33ee1e4a282e1 371 PIRSF PIRSF000390 1 371 2.4E-99 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A6A12_RS13310 768a63c16d33874db8f33ee1e4a282e1 371 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 14 366 2.1E-125 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase A6A12_RS13310 768a63c16d33874db8f33ee1e4a282e1 371 SUPERFAMILY SSF53383 13 370 2.09E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS09020 242673e91e37eb6dacf559d75aac6855 414 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 5 413 8.7E-153 T 28-03-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 A6A12_RS09020 242673e91e37eb6dacf559d75aac6855 414 Pfam PF12704 MacB-like periplasmic core domain 29 241 1.7E-14 T 28-03-2018 IPR025857 MacB-like periplasmic core domain A6A12_RS09020 242673e91e37eb6dacf559d75aac6855 414 TIGRFAM TIGR02213 lolE_release: lipoprotein releasing system, transmembrane protein LolE 4 414 7.5E-204 T 28-03-2018 IPR011926 Lipoprotein-releasing system transmembrane protein LolC/E, gammaproteobacteria type GO:0006810|GO:0009276|GO:0016021 A6A12_RS09020 242673e91e37eb6dacf559d75aac6855 414 Pfam PF02687 FtsX-like permease family 301 407 3.1E-13 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A6A12_RS01380 955ec5cdbd2772c8e560d78c9067f2d2 122 Pfam PF01250 Ribosomal protein S6 3 91 5.7E-28 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01380 955ec5cdbd2772c8e560d78c9067f2d2 122 Gene3D G3DSA:3.30.70.60 1 100 1.6E-30 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A6A12_RS01380 955ec5cdbd2772c8e560d78c9067f2d2 122 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 3.2E-38 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01380 955ec5cdbd2772c8e560d78c9067f2d2 122 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.867 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 A6A12_RS01380 955ec5cdbd2772c8e560d78c9067f2d2 122 SUPERFAMILY SSF54995 1 103 2.62E-38 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02925 d4b1979d4b349bf3c5a180daf3480714 209 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 15 208 28.697 T 28-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 A6A12_RS02925 d4b1979d4b349bf3c5a180daf3480714 209 SUPERFAMILY SSF53335 30 209 1.08E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS02925 d4b1979d4b349bf3c5a180daf3480714 209 Pfam PF01728 FtsJ-like methyltransferase 31 207 1.6E-55 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 A6A12_RS02925 d4b1979d4b349bf3c5a180daf3480714 209 PIRSF PIRSF005461 1 209 1.2E-80 T 28-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 A6A12_RS02925 d4b1979d4b349bf3c5a180daf3480714 209 Gene3D G3DSA:3.40.50.150 1 209 4.1E-57 T 28-03-2018 A6A12_RS00305 375fe634a89c291c342558e855f0607e 304 PIRSF PIRSF000166 2 304 2.1E-127 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A6A12_RS00305 375fe634a89c291c342558e855f0607e 304 Pfam PF01218 Coproporphyrinogen III oxidase 9 304 2.1E-129 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A6A12_RS00305 375fe634a89c291c342558e855f0607e 304 Gene3D G3DSA:3.40.1500.10 2 304 4.5E-137 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A6A12_RS00305 375fe634a89c291c342558e855f0607e 304 SUPERFAMILY SSF102886 5 304 2.09E-133 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A6A12_RS00305 375fe634a89c291c342558e855f0607e 304 PRINTS PR00073 Coprogen oxidase signature 166 195 1.7E-67 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A6A12_RS00305 375fe634a89c291c342558e855f0607e 304 PRINTS PR00073 Coprogen oxidase signature 31 47 1.7E-67 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A6A12_RS00305 375fe634a89c291c342558e855f0607e 304 PRINTS PR00073 Coprogen oxidase signature 266 292 1.7E-67 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A6A12_RS00305 375fe634a89c291c342558e855f0607e 304 PRINTS PR00073 Coprogen oxidase signature 238 265 1.7E-67 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A6A12_RS00305 375fe634a89c291c342558e855f0607e 304 PRINTS PR00073 Coprogen oxidase signature 129 151 1.7E-67 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A6A12_RS00305 375fe634a89c291c342558e855f0607e 304 PRINTS PR00073 Coprogen oxidase signature 94 118 1.7E-67 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A6A12_RS00305 375fe634a89c291c342558e855f0607e 304 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 3 281 56.512 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A6A12_RS00305 375fe634a89c291c342558e855f0607e 304 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 170 194 - T 28-03-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 A6A12_RS12295 a62850c4b9fff16a7ac1c88c777fe987 205 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 14 196 1.9E-82 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A6A12_RS12295 a62850c4b9fff16a7ac1c88c777fe987 205 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 30 202 37.98 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A6A12_RS12295 a62850c4b9fff16a7ac1c88c777fe987 205 Pfam PF01583 Adenylylsulphate kinase 31 185 8.6E-72 T 28-03-2018 A6A12_RS12295 a62850c4b9fff16a7ac1c88c777fe987 205 Gene3D G3DSA:3.40.50.300 27 205 1.5E-50 T 28-03-2018 A6A12_RS12295 a62850c4b9fff16a7ac1c88c777fe987 205 SUPERFAMILY SSF52540 24 198 1.23E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12600 f1583df60a1d697a682b4a675b40792c 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 242 249 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A6A12_RS12600 f1583df60a1d697a682b4a675b40792c 485 TIGRFAM TIGR03240 arg_catab_astD: succinylglutamate-semialdehyde dehydrogenase 3 484 6.4E-224 T 28-03-2018 IPR017649 Succinylglutamate-semialdehyde dehydrogenase GO:0006527|GO:0043824|GO:0055114 KEGG: 00330+1.2.1.71 A6A12_RS12600 f1583df60a1d697a682b4a675b40792c 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 271 282 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A6A12_RS12600 f1583df60a1d697a682b4a675b40792c 485 Gene3D G3DSA:3.40.605.10 1 258 7.0E-73 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A6A12_RS12600 f1583df60a1d697a682b4a675b40792c 485 SUPERFAMILY SSF53720 3 449 4.06E-122 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A6A12_RS12600 f1583df60a1d697a682b4a675b40792c 485 Hamap MF_01174 N-succinylglutamate 5-semialdehyde dehydrogenase [astD]. 1 485 55.767 T 28-03-2018 IPR017649 Succinylglutamate-semialdehyde dehydrogenase GO:0006527|GO:0043824|GO:0055114 KEGG: 00330+1.2.1.71 A6A12_RS12600 f1583df60a1d697a682b4a675b40792c 485 Pfam PF00171 Aldehyde dehydrogenase family 9 458 2.7E-120 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A6A12_RS12600 f1583df60a1d697a682b4a675b40792c 485 Gene3D G3DSA:3.40.309.10 259 442 2.7E-44 T 28-03-2018 A6A12_RS05760 1058b0fa9c03d0ef1a8e7c1827d364d7 335 Hamap MF_01277 HTH-type transcriptional repressor PurR [purR]. 1 334 63.809 T 28-03-2018 IPR023588 Transcription regulator HTH, PurR GO:0006355 A6A12_RS05760 1058b0fa9c03d0ef1a8e7c1827d364d7 335 Gene3D G3DSA:3.40.50.2300 176 313 1.3E-47 T 28-03-2018 A6A12_RS05760 1058b0fa9c03d0ef1a8e7c1827d364d7 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 A6A12_RS05760 1058b0fa9c03d0ef1a8e7c1827d364d7 335 SUPERFAMILY SSF53822 60 332 1.73E-94 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A6A12_RS05760 1058b0fa9c03d0ef1a8e7c1827d364d7 335 Pfam PF13377 Periplasmic binding protein-like domain 170 330 1.8E-43 T 28-03-2018 A6A12_RS05760 1058b0fa9c03d0ef1a8e7c1827d364d7 335 Gene3D G3DSA:1.10.260.40 2 54 2.2E-21 T 28-03-2018 A6A12_RS05760 1058b0fa9c03d0ef1a8e7c1827d364d7 335 SMART SM00354 1 71 1.9E-37 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS05760 1058b0fa9c03d0ef1a8e7c1827d364d7 335 SUPERFAMILY SSF47413 1 59 1.65E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS05760 1058b0fa9c03d0ef1a8e7c1827d364d7 335 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.0E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS05760 1058b0fa9c03d0ef1a8e7c1827d364d7 335 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.0E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS05760 1058b0fa9c03d0ef1a8e7c1827d364d7 335 Gene3D G3DSA:3.40.50.2300 55 175 1.4E-32 T 28-03-2018 A6A12_RS05760 1058b0fa9c03d0ef1a8e7c1827d364d7 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 8.3E-21 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 A6A12_RS03685 4bb0a48ed1a2ec118a8b305f4d28411c 112 TIGRFAM TIGR03582 EF_0829: PRD domain protein, EF_0829/AHA_3910 family 12 100 7.7E-36 T 28-03-2018 IPR020044 PRD domain protein, EF0829/AHA3910 A6A12_RS03685 4bb0a48ed1a2ec118a8b305f4d28411c 112 Gene3D G3DSA:1.10.1790.10 1 101 1.7E-7 T 28-03-2018 IPR011608 PRD domain GO:0006355 A6A12_RS03685 4bb0a48ed1a2ec118a8b305f4d28411c 112 SUPERFAMILY SSF63520 21 100 1.03E-7 T 28-03-2018 IPR011608 PRD domain GO:0006355 A6A12_RS09940 0dd8e985b33ed25a627d2296cf113c8b 925 Pfam PF00675 Insulinase (Peptidase family M16) 23 158 2.1E-37 T 28-03-2018 IPR011765 Peptidase M16, N-terminal A6A12_RS09940 0dd8e985b33ed25a627d2296cf113c8b 925 SUPERFAMILY SSF63411 232 458 1.05E-71 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A6A12_RS09940 0dd8e985b33ed25a627d2296cf113c8b 925 Gene3D G3DSA:3.30.830.10 694 923 1.0E-30 T 28-03-2018 A6A12_RS09940 0dd8e985b33ed25a627d2296cf113c8b 925 Gene3D G3DSA:3.30.830.10 1 228 7.0E-85 T 28-03-2018 A6A12_RS09940 0dd8e985b33ed25a627d2296cf113c8b 925 SUPERFAMILY SSF63411 469 694 2.2E-57 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A6A12_RS09940 0dd8e985b33ed25a627d2296cf113c8b 925 Pfam PF05193 Peptidase M16 inactive domain 182 354 1.4E-23 T 28-03-2018 IPR007863 Peptidase M16, C-terminal A6A12_RS09940 0dd8e985b33ed25a627d2296cf113c8b 925 Pfam PF05193 Peptidase M16 inactive domain 648 824 2.4E-10 T 28-03-2018 IPR007863 Peptidase M16, C-terminal A6A12_RS09940 0dd8e985b33ed25a627d2296cf113c8b 925 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 42 65 - T 28-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 A6A12_RS09940 0dd8e985b33ed25a627d2296cf113c8b 925 SUPERFAMILY SSF63411 703 916 8.17E-45 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A6A12_RS09940 0dd8e985b33ed25a627d2296cf113c8b 925 Gene3D G3DSA:3.30.830.10 468 693 6.6E-32 T 28-03-2018 A6A12_RS09940 0dd8e985b33ed25a627d2296cf113c8b 925 SUPERFAMILY SSF63411 4 227 6.46E-61 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 A6A12_RS09940 0dd8e985b33ed25a627d2296cf113c8b 925 Gene3D G3DSA:3.30.830.10 230 457 8.5E-67 T 28-03-2018 A6A12_RS09940 0dd8e985b33ed25a627d2296cf113c8b 925 Pfam PF16187 Middle or third domain of peptidase_M16 366 642 5.5E-81 T 28-03-2018 IPR032632 Peptidase M16, middle/third domain A6A12_RS13400 2a98ad550795ca8f876a1b455d00e7b8 181 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 177 1.0E-100 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A6A12_RS13400 2a98ad550795ca8f876a1b455d00e7b8 181 Gene3D G3DSA:2.60.120.10 1 180 5.4E-83 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS13400 2a98ad550795ca8f876a1b455d00e7b8 181 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 176 3.8E-77 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A6A12_RS13400 2a98ad550795ca8f876a1b455d00e7b8 181 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 177 3.0E-86 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A6A12_RS13400 2a98ad550795ca8f876a1b455d00e7b8 181 SUPERFAMILY SSF51182 1 179 2.14E-81 T 28-03-2018 IPR011051 RmlC-like cupin domain A6A12_RS14185 cfe09507a23b6392f69a944e874c995b 291 TIGRFAM TIGR00950 2A78: carboxylate/amino acid/amine transporter 11 274 3.3E-70 T 28-03-2018 IPR004779 Carboxylate/Amino Acid/Amine Transporter GO:0016021 A6A12_RS14185 cfe09507a23b6392f69a944e874c995b 291 Pfam PF00892 EamA-like transporter family 138 276 3.2E-6 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A6A12_RS14185 cfe09507a23b6392f69a944e874c995b 291 SUPERFAMILY SSF103481 183 275 1.29E-5 T 28-03-2018 A6A12_RS13315 ee93238e49f3f1961820f12db8dfe835 151 Gene3D G3DSA:2.160.10.10 1 86 8.2E-19 T 28-03-2018 A6A12_RS13315 ee93238e49f3f1961820f12db8dfe835 151 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 107 135 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A6A12_RS13315 ee93238e49f3f1961820f12db8dfe835 151 Gene3D G3DSA:2.160.10.10 90 151 1.9E-22 T 28-03-2018 A6A12_RS13315 ee93238e49f3f1961820f12db8dfe835 151 SUPERFAMILY SSF51161 14 151 1.96E-43 T 28-03-2018 IPR011004 Trimeric LpxA-like A6A12_RS13315 ee93238e49f3f1961820f12db8dfe835 151 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 48 82 1.0E-7 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS13315 ee93238e49f3f1961820f12db8dfe835 151 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 99 133 8.6E-9 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS13315 ee93238e49f3f1961820f12db8dfe835 151 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 13 46 1.0E-7 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS09445 54328ad5fda278640bdfa33a560bbc48 499 Gene3D G3DSA:3.40.50.980 144 152 0.0068 T 28-03-2018 A6A12_RS09445 54328ad5fda278640bdfa33a560bbc48 499 Gene3D G3DSA:3.40.50.980 1 143 1.7E-20 T 28-03-2018 A6A12_RS09445 54328ad5fda278640bdfa33a560bbc48 499 Gene3D G3DSA:3.30.300.30 372 478 1.3E-5 T 28-03-2018 A6A12_RS09445 54328ad5fda278640bdfa33a560bbc48 499 Gene3D G3DSA:3.40.50.980 153 308 2.8E-28 T 28-03-2018 A6A12_RS09445 54328ad5fda278640bdfa33a560bbc48 499 Gene3D G3DSA:2.30.38.10 309 370 1.9E-8 T 28-03-2018 A6A12_RS09445 54328ad5fda278640bdfa33a560bbc48 499 SUPERFAMILY SSF56801 3 472 1.83E-76 T 28-03-2018 A6A12_RS09445 54328ad5fda278640bdfa33a560bbc48 499 ProSitePatterns PS00455 Putative AMP-binding domain signature. 142 153 - T 28-03-2018 IPR020845 AMP-binding, conserved site A6A12_RS09445 54328ad5fda278640bdfa33a560bbc48 499 Pfam PF00501 AMP-binding enzyme 9 377 1.4E-54 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A6A12_RS00205 202dba6fa8ec787b73622416ea4fe244 199 PIRSF PIRSF001488 1 199 1.5E-70 T 28-03-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL A6A12_RS00205 202dba6fa8ec787b73622416ea4fe244 199 ProSitePatterns PS00194 Thioredoxin family active site. 41 59 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A6A12_RS00205 202dba6fa8ec787b73622416ea4fe244 199 Gene3D G3DSA:3.40.30.10 17 199 1.0E-41 T 28-03-2018 A6A12_RS00205 202dba6fa8ec787b73622416ea4fe244 199 Pfam PF01323 DSBA-like thioredoxin domain 40 180 2.4E-29 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 A6A12_RS00205 202dba6fa8ec787b73622416ea4fe244 199 SUPERFAMILY SSF52833 21 197 1.28E-43 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS00320 8ed5568871fdf3da4163b7edc063274b 182 Gene3D G3DSA:2.160.10.10 1 182 1.1E-39 T 28-03-2018 A6A12_RS00320 8ed5568871fdf3da4163b7edc063274b 182 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 96 129 1.5E-6 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS00320 8ed5568871fdf3da4163b7edc063274b 182 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 40 8.5E-5 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS00320 8ed5568871fdf3da4163b7edc063274b 182 SUPERFAMILY SSF51161 4 174 1.8E-44 T 28-03-2018 IPR011004 Trimeric LpxA-like A6A12_RS01795 f8cbead23ac1f7534ae0fbe675aba208 126 SUPERFAMILY SSF110069 6 126 1.19E-47 T 28-03-2018 IPR007474 ApaG domain A6A12_RS01795 f8cbead23ac1f7534ae0fbe675aba208 126 Pfam PF04379 ApaG domain 18 102 5.5E-33 T 28-03-2018 IPR007474 ApaG domain A6A12_RS01795 f8cbead23ac1f7534ae0fbe675aba208 126 Hamap MF_00791 Protein ApaG [apaG]. 1 126 31.502 T 28-03-2018 IPR023065 Uncharacterised protein family ApaG A6A12_RS01795 f8cbead23ac1f7534ae0fbe675aba208 126 Gene3D G3DSA:2.60.40.1470 2 126 4.5E-43 T 28-03-2018 IPR007474 ApaG domain A6A12_RS06935 8cf1be4d97ef4676f156face1fc96ce4 258 Gene3D G3DSA:3.60.15.10 1 238 4.2E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS06935 8cf1be4d97ef4676f156face1fc96ce4 258 SUPERFAMILY SSF56281 8 227 1.83E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS06935 8cf1be4d97ef4676f156face1fc96ce4 258 SMART SM00849 10 209 1.3E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS06935 8cf1be4d97ef4676f156face1fc96ce4 258 Pfam PF00753 Metallo-beta-lactamase superfamily 9 209 6.5E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS03060 cc0cd29d3843494abe12eeaa8c8e0da5 240 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 142 166 1.6E-6 T 28-03-2018 A6A12_RS03060 cc0cd29d3843494abe12eeaa8c8e0da5 240 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 47 61 1.6E-6 T 28-03-2018 A6A12_RS03060 cc0cd29d3843494abe12eeaa8c8e0da5 240 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 112 124 1.6E-6 T 28-03-2018 A6A12_RS03060 cc0cd29d3843494abe12eeaa8c8e0da5 240 Pfam PF05175 Methyltransferase small domain 43 160 9.0E-18 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 A6A12_RS03060 cc0cd29d3843494abe12eeaa8c8e0da5 240 Gene3D G3DSA:3.40.50.150 31 234 1.6E-34 T 28-03-2018 A6A12_RS03060 cc0cd29d3843494abe12eeaa8c8e0da5 240 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 115 121 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A6A12_RS03060 cc0cd29d3843494abe12eeaa8c8e0da5 240 Hamap MF_01872 tRNA1(Val) (adenine(37)-N6)-methyltransferase [yfiC]. 10 240 53.461 T 28-03-2018 IPR022882 tRNA1(Val) (adenine(37)-N6)-methyltransferase GO:0016430 KEGG: 00340+2.1.1.22 A6A12_RS03060 cc0cd29d3843494abe12eeaa8c8e0da5 240 SUPERFAMILY SSF53335 11 171 2.99E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS09785 a91d9c5924d3d7d7be966828a9d41887 296 Pfam PF02634 FdhD/NarQ family 41 291 1.9E-63 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A6A12_RS09785 a91d9c5924d3d7d7be966828a9d41887 296 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 15 292 27.21 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A6A12_RS09785 a91d9c5924d3d7d7be966828a9d41887 296 Gene3D G3DSA:3.10.20.10 42 141 1.3E-17 T 28-03-2018 A6A12_RS09785 a91d9c5924d3d7d7be966828a9d41887 296 PIRSF PIRSF015626 5 295 2.1E-64 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 A6A12_RS09785 a91d9c5924d3d7d7be966828a9d41887 296 Gene3D G3DSA:3.40.140.10 158 296 2.3E-48 T 28-03-2018 A6A12_RS09785 a91d9c5924d3d7d7be966828a9d41887 296 SUPERFAMILY SSF53927 32 291 1.8E-62 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A6A12_RS12680 5644ed5833240ee5372c04b0acb12612 173 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A6A12_RS12680 5644ed5833240ee5372c04b0acb12612 173 Gene3D G3DSA:3.40.50.300 1 172 1.4E-34 T 28-03-2018 A6A12_RS12680 5644ed5833240ee5372c04b0acb12612 173 SUPERFAMILY SSF52540 4 169 2.1E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12680 5644ed5833240ee5372c04b0acb12612 173 PRINTS PR01100 Shikimate kinase family signature 31 44 5.3E-29 T 28-03-2018 A6A12_RS12680 5644ed5833240ee5372c04b0acb12612 173 PRINTS PR01100 Shikimate kinase family signature 59 67 5.3E-29 T 28-03-2018 A6A12_RS12680 5644ed5833240ee5372c04b0acb12612 173 PRINTS PR01100 Shikimate kinase family signature 7 22 5.3E-29 T 28-03-2018 A6A12_RS12680 5644ed5833240ee5372c04b0acb12612 173 PRINTS PR01100 Shikimate kinase family signature 98 115 5.3E-29 T 28-03-2018 A6A12_RS12680 5644ed5833240ee5372c04b0acb12612 173 PRINTS PR01100 Shikimate kinase family signature 77 86 5.3E-29 T 28-03-2018 A6A12_RS12680 5644ed5833240ee5372c04b0acb12612 173 Hamap MF_00109 Shikimate kinase [aroK]. 4 170 28.899 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A6A12_RS12680 5644ed5833240ee5372c04b0acb12612 173 Pfam PF01202 Shikimate kinase 13 169 3.2E-55 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 A6A12_RS12740 9545ee3e8fbb7054992a9d9ce87e0916 407 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 12 20 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS12740 9545ee3e8fbb7054992a9d9ce87e0916 407 Gene3D G3DSA:3.40.50.620 2 167 1.5E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS12740 9545ee3e8fbb7054992a9d9ce87e0916 407 Pfam PF00764 Arginosuccinate synthase 10 396 2.6E-143 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS12740 9545ee3e8fbb7054992a9d9ce87e0916 407 Gene3D G3DSA:3.90.1260.10 168 358 9.8E-80 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS12740 9545ee3e8fbb7054992a9d9ce87e0916 407 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 121 132 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS12740 9545ee3e8fbb7054992a9d9ce87e0916 407 Gene3D G3DSA:1.20.5.470 368 401 1.6E-12 T 28-03-2018 A6A12_RS12740 9545ee3e8fbb7054992a9d9ce87e0916 407 SUPERFAMILY SSF52402 7 170 3.31E-47 T 28-03-2018 A6A12_RS12740 9545ee3e8fbb7054992a9d9ce87e0916 407 Hamap MF_00005 Argininosuccinate synthase [argG]. 6 402 51.426 T 28-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS12740 9545ee3e8fbb7054992a9d9ce87e0916 407 TIGRFAM TIGR00032 argG: argininosuccinate synthase 8 395 3.4E-134 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS12740 9545ee3e8fbb7054992a9d9ce87e0916 407 SUPERFAMILY SSF69864 177 401 3.14E-85 T 28-03-2018 A6A12_RS05000 589aca097ceff46a07cd55fe6135b400 647 Gene3D G3DSA:3.40.50.300 18 422 2.6E-30 T 28-03-2018 A6A12_RS05000 589aca097ceff46a07cd55fe6135b400 647 SUPERFAMILY SSF52540 15 235 5.62E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05000 589aca097ceff46a07cd55fe6135b400 647 Gene3D G3DSA:3.40.50.300 446 637 3.1E-12 T 28-03-2018 A6A12_RS05000 589aca097ceff46a07cd55fe6135b400 647 SMART SM00487 17 299 0.0065 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS05000 589aca097ceff46a07cd55fe6135b400 647 Pfam PF13307 Helicase C-terminal domain 462 619 7.2E-35 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A6A12_RS05000 589aca097ceff46a07cd55fe6135b400 647 Pfam PF00270 DEAD/DEAH box helicase 29 82 2.2E-5 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A6A12_RS05000 589aca097ceff46a07cd55fe6135b400 647 SUPERFAMILY SSF52540 42 89 1.38E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05000 589aca097ceff46a07cd55fe6135b400 647 SUPERFAMILY SSF52540 480 545 1.38E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05000 589aca097ceff46a07cd55fe6135b400 647 SUPERFAMILY SSF52540 576 602 1.38E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05000 589aca097ceff46a07cd55fe6135b400 647 SMART SM00491 477 606 1.0E-45 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A6A12_RS03150 7e3c62a89f6baaa58ce52007bb3b92db 487 Gene3D G3DSA:1.20.58.60 172 327 1.6E-4 T 28-03-2018 A6A12_RS03150 7e3c62a89f6baaa58ce52007bb3b92db 487 Gene3D G3DSA:1.20.120.330 4 149 0.063 T 28-03-2018 A6A12_RS07775 2da20796f5038243d120a46487587473 231 SUPERFAMILY SSF53850 25 229 1.74E-23 T 28-03-2018 A6A12_RS07775 2da20796f5038243d120a46487587473 231 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 30 229 9.8E-9 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS07775 2da20796f5038243d120a46487587473 231 Gene3D G3DSA:3.40.190.10 130 230 1.3E-4 T 28-03-2018 A6A12_RS07775 2da20796f5038243d120a46487587473 231 Gene3D G3DSA:3.40.190.10 17 129 1.7E-8 T 28-03-2018 A6A12_RS05285 4f74b81bd7ccc6d4d24b4d80ca50ffa1 287 Pfam PF01435 Peptidase family M48 78 286 4.5E-40 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A6A12_RS05285 4f74b81bd7ccc6d4d24b4d80ca50ffa1 287 Hamap MF_00188 Protease HtpX [htpX]. 1 287 25.226 T 28-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 A6A12_RS05285 4f74b81bd7ccc6d4d24b4d80ca50ffa1 287 Gene3D G3DSA:1.20.1250.20 156 242 0.19 T 28-03-2018 A6A12_RS05285 4f74b81bd7ccc6d4d24b4d80ca50ffa1 287 Gene3D G3DSA:1.20.1250.20 2 79 0.13 T 28-03-2018 A6A12_RS05285 4f74b81bd7ccc6d4d24b4d80ca50ffa1 287 Gene3D G3DSA:3.30.2010.10 80 155 4.1E-22 T 28-03-2018 A6A12_RS11820 f6f3ce6b283a5bf73f7efe8a4cdcec12 326 Pfam PF17188 MucB/RseB C-terminal domain 218 311 2.5E-27 T 28-03-2018 IPR033436 MucB/RseB, C-terminal A6A12_RS11820 f6f3ce6b283a5bf73f7efe8a4cdcec12 326 Pfam PF03888 MucB/RseB N-terminal domain 26 196 9.7E-59 T 28-03-2018 IPR033434 MucB/RseB, N-terminal A6A12_RS11820 f6f3ce6b283a5bf73f7efe8a4cdcec12 326 Gene3D G3DSA:2.50.20.10 19 258 6.1E-21 T 28-03-2018 A6A12_RS11820 f6f3ce6b283a5bf73f7efe8a4cdcec12 326 PIRSF PIRSF005427 1 318 2.9E-81 T 28-03-2018 IPR005588 MucB/RseB A6A12_RS11590 d405f37a959754875310890677557064 196 Pfam PF13580 SIS domain 9 144 4.1E-34 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A6A12_RS11590 d405f37a959754875310890677557064 196 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 190 34.311 T 28-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 A6A12_RS11590 d405f37a959754875310890677557064 196 Gene3D G3DSA:3.40.50.10490 1 196 1.0E-38 T 28-03-2018 A6A12_RS11590 d405f37a959754875310890677557064 196 SUPERFAMILY SSF53697 1 191 1.72E-57 T 28-03-2018 A6A12_RS04210 cc94fc3b777a5be1911d32a45fd8070c 175 SUPERFAMILY SSF52788 10 160 2.35E-45 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A6A12_RS04210 cc94fc3b777a5be1911d32a45fd8070c 175 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 15 154 7.0E-37 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A6A12_RS04210 cc94fc3b777a5be1911d32a45fd8070c 175 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 131 146 3.9E-23 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A6A12_RS04210 cc94fc3b777a5be1911d32a45fd8070c 175 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 90 105 3.9E-23 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A6A12_RS04210 cc94fc3b777a5be1911d32a45fd8070c 175 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 15 32 3.9E-23 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A6A12_RS04210 cc94fc3b777a5be1911d32a45fd8070c 175 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 56 72 3.9E-23 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 A6A12_RS04210 cc94fc3b777a5be1911d32a45fd8070c 175 SMART SM00226 13 159 1.8E-39 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily A6A12_RS04210 cc94fc3b777a5be1911d32a45fd8070c 175 Gene3D G3DSA:3.40.50.2300 7 168 1.6E-46 T 28-03-2018 A6A12_RS05260 4fc47bf50bc4fc639bf79168ff0c31fe 398 Pfam PF13679 Methyltransferase domain 108 231 2.5E-15 T 28-03-2018 IPR025714 Methyltransferase domain A6A12_RS05260 4fc47bf50bc4fc639bf79168ff0c31fe 398 Gene3D G3DSA:3.40.50.150 75 357 5.5E-6 T 28-03-2018 A6A12_RS05260 4fc47bf50bc4fc639bf79168ff0c31fe 398 SUPERFAMILY SSF53335 97 183 5.43E-7 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS03490 9854c2dfd8f3cb43268f83efcdef006f 242 Pfam PF00588 SpoU rRNA Methylase family 5 153 3.4E-33 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A6A12_RS03490 9854c2dfd8f3cb43268f83efcdef006f 242 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 238 1.1E-80 T 28-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 A6A12_RS03490 9854c2dfd8f3cb43268f83efcdef006f 242 SUPERFAMILY SSF75217 4 166 1.05E-35 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases A6A12_RS03490 9854c2dfd8f3cb43268f83efcdef006f 242 PIRSF PIRSF004808 1 242 1.9E-72 T 28-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 A6A12_RS03490 9854c2dfd8f3cb43268f83efcdef006f 242 Gene3D G3DSA:3.40.1280.10 1 165 1.3E-40 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A6A12_RS08275 35b69102c0f73297da78eb53f4d6cafe 132 Gene3D G3DSA:3.40.50.300 16 126 2.2E-6 T 28-03-2018 A6A12_RS08275 35b69102c0f73297da78eb53f4d6cafe 132 SUPERFAMILY SSF52540 27 124 1.86E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS14425 f6fdd60d6800fe4d6d0c757c265930f1 86 Pfam PF01809 Haemolytic domain 11 75 1.2E-28 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor A6A12_RS14425 f6fdd60d6800fe4d6d0c757c265930f1 86 SMART SM01234 8 75 4.8E-42 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor A6A12_RS14425 f6fdd60d6800fe4d6d0c757c265930f1 86 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 14 83 6.5E-32 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor A6A12_RS14425 f6fdd60d6800fe4d6d0c757c265930f1 86 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 8 76 24.533 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor A6A12_RS14425 f6fdd60d6800fe4d6d0c757c265930f1 86 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 23 75 1.0E-23 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor A6A12_RS13285 f085c3262fb6fd56aae8ca3c1cf10272 628 Pfam PF02719 Polysaccharide biosynthesis protein 284 578 1.7E-127 T 28-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain A6A12_RS13285 f085c3262fb6fd56aae8ca3c1cf10272 628 SUPERFAMILY SSF53335 110 330 4.48E-16 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS13285 f085c3262fb6fd56aae8ca3c1cf10272 628 SUPERFAMILY SSF51735 282 594 3.31E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS13285 f085c3262fb6fd56aae8ca3c1cf10272 628 Gene3D G3DSA:3.40.50.720 277 615 6.3E-60 T 28-03-2018 A6A12_RS13285 f085c3262fb6fd56aae8ca3c1cf10272 628 Gene3D G3DSA:3.40.50.720 141 265 3.4E-16 T 28-03-2018 A6A12_RS04405 319501378531a8bfeee02a8daa2a8072 291 Gene3D G3DSA:3.10.580.10 48 197 2.2E-35 T 28-03-2018 A6A12_RS04405 319501378531a8bfeee02a8daa2a8072 291 SMART SM01091 203 281 7.1E-31 T 28-03-2018 IPR005170 Transporter-associated domain A6A12_RS04405 319501378531a8bfeee02a8daa2a8072 291 SUPERFAMILY SSF56176 198 280 5.73E-23 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A6A12_RS04405 319501378531a8bfeee02a8daa2a8072 291 SMART SM00116 76 125 0.0015 T 28-03-2018 IPR000644 CBS domain A6A12_RS04405 319501378531a8bfeee02a8daa2a8072 291 SMART SM00116 139 187 0.028 T 28-03-2018 IPR000644 CBS domain A6A12_RS04405 319501378531a8bfeee02a8daa2a8072 291 Pfam PF03471 Transporter associated domain 204 279 2.2E-23 T 28-03-2018 IPR005170 Transporter-associated domain A6A12_RS04405 319501378531a8bfeee02a8daa2a8072 291 Gene3D G3DSA:3.30.465.10 198 279 5.3E-27 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A6A12_RS04405 319501378531a8bfeee02a8daa2a8072 291 Pfam PF00571 CBS domain 138 187 2.1E-6 T 28-03-2018 IPR000644 CBS domain A6A12_RS04405 319501378531a8bfeee02a8daa2a8072 291 Pfam PF00571 CBS domain 67 124 5.0E-9 T 28-03-2018 IPR000644 CBS domain A6A12_RS04405 319501378531a8bfeee02a8daa2a8072 291 SUPERFAMILY SSF54631 63 200 9.91E-34 T 28-03-2018 A6A12_RS10655 5da5a7fe303855a897ca23c95acddfa4 275 Gene3D G3DSA:1.10.155.10 1 74 1.8E-12 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal A6A12_RS10655 5da5a7fe303855a897ca23c95acddfa4 275 SMART SM00138 8 272 5.4E-138 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A6A12_RS10655 5da5a7fe303855a897ca23c95acddfa4 275 SUPERFAMILY SSF47757 3 75 8.5E-15 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal A6A12_RS10655 5da5a7fe303855a897ca23c95acddfa4 275 SUPERFAMILY SSF53335 76 269 1.23E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS10655 5da5a7fe303855a897ca23c95acddfa4 275 Pfam PF03705 CheR methyltransferase, all-alpha domain 9 57 5.1E-10 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal A6A12_RS10655 5da5a7fe303855a897ca23c95acddfa4 275 Pfam PF01739 CheR methyltransferase, SAM binding domain 76 269 2.3E-68 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal A6A12_RS10655 5da5a7fe303855a897ca23c95acddfa4 275 PRINTS PR00996 Glutamate methyltransferase family signature 143 159 3.6E-43 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A6A12_RS10655 5da5a7fe303855a897ca23c95acddfa4 275 PRINTS PR00996 Glutamate methyltransferase family signature 30 43 3.6E-43 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A6A12_RS10655 5da5a7fe303855a897ca23c95acddfa4 275 PRINTS PR00996 Glutamate methyltransferase family signature 106 126 3.6E-43 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A6A12_RS10655 5da5a7fe303855a897ca23c95acddfa4 275 PRINTS PR00996 Glutamate methyltransferase family signature 231 254 3.6E-43 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A6A12_RS10655 5da5a7fe303855a897ca23c95acddfa4 275 PRINTS PR00996 Glutamate methyltransferase family signature 212 226 3.6E-43 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A6A12_RS10655 5da5a7fe303855a897ca23c95acddfa4 275 PRINTS PR00996 Glutamate methyltransferase family signature 69 81 3.6E-43 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A6A12_RS10655 5da5a7fe303855a897ca23c95acddfa4 275 Gene3D G3DSA:3.40.50.150 75 274 1.3E-45 T 28-03-2018 A6A12_RS04230 b04535699a23a3375fb0686be3420f35 306 SUPERFAMILY SSF53448 3 253 9.64E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS04230 b04535699a23a3375fb0686be3420f35 306 Gene3D G3DSA:3.90.550.10 7 255 3.1E-25 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS04230 b04535699a23a3375fb0686be3420f35 306 Pfam PF00535 Glycosyl transferase family 2 10 163 1.3E-13 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A6A12_RS10610 28840459fc477c7798b41385d59a90f4 307 SMART SM00047 146 304 6.2E-48 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 A6A12_RS10610 28840459fc477c7798b41385d59a90f4 307 PRINTS PR01002 Flagellar protein FlgJ signature 221 242 1.7E-30 T 28-03-2018 A6A12_RS10610 28840459fc477c7798b41385d59a90f4 307 PRINTS PR01002 Flagellar protein FlgJ signature 79 101 1.7E-30 T 28-03-2018 A6A12_RS10610 28840459fc477c7798b41385d59a90f4 307 PRINTS PR01002 Flagellar protein FlgJ signature 31 54 1.7E-30 T 28-03-2018 A6A12_RS10610 28840459fc477c7798b41385d59a90f4 307 PRINTS PR01002 Flagellar protein FlgJ signature 156 179 1.7E-30 T 28-03-2018 A6A12_RS10610 28840459fc477c7798b41385d59a90f4 307 PRINTS PR01002 Flagellar protein FlgJ signature 286 304 1.7E-30 T 28-03-2018 A6A12_RS10610 28840459fc477c7798b41385d59a90f4 307 PRINTS PR01002 Flagellar protein FlgJ signature 180 198 1.7E-30 T 28-03-2018 A6A12_RS10610 28840459fc477c7798b41385d59a90f4 307 PRINTS PR01002 Flagellar protein FlgJ signature 243 264 1.7E-30 T 28-03-2018 A6A12_RS10610 28840459fc477c7798b41385d59a90f4 307 SUPERFAMILY SSF53955 127 198 7.31E-5 T 28-03-2018 IPR023346 Lysozyme-like domain A6A12_RS10610 28840459fc477c7798b41385d59a90f4 307 Pfam PF10135 Rod binding protein 53 102 2.3E-15 T 28-03-2018 IPR019301 Flagellar protein FlgJ, N-terminal A6A12_RS10610 28840459fc477c7798b41385d59a90f4 307 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 167 303 8.3E-20 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 A6A12_RS10610 28840459fc477c7798b41385d59a90f4 307 Gene3D G3DSA:1.10.530.10 150 306 2.6E-32 T 28-03-2018 A6A12_RS10610 28840459fc477c7798b41385d59a90f4 307 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 10 303 3.2E-105 T 28-03-2018 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 A6A12_RS12160 d6050924a0bd69c700ccae845923fd6b 486 PRINTS PR00045 Sigma-54 factor signature 459 477 3.4E-30 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A6A12_RS12160 d6050924a0bd69c700ccae845923fd6b 486 PRINTS PR00045 Sigma-54 factor signature 385 397 3.4E-30 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A6A12_RS12160 d6050924a0bd69c700ccae845923fd6b 486 PRINTS PR00045 Sigma-54 factor signature 401 412 3.4E-30 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A6A12_RS12160 d6050924a0bd69c700ccae845923fd6b 486 PRINTS PR00045 Sigma-54 factor signature 197 214 3.4E-30 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A6A12_RS12160 d6050924a0bd69c700ccae845923fd6b 486 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 4 49 4.0E-17 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A6A12_RS12160 d6050924a0bd69c700ccae845923fd6b 486 Pfam PF04552 Sigma-54, DNA binding domain 326 484 7.8E-73 T 28-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding A6A12_RS12160 d6050924a0bd69c700ccae845923fd6b 486 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 483 9.7E-156 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A6A12_RS12160 d6050924a0bd69c700ccae845923fd6b 486 Pfam PF04963 Sigma-54 factor, core binding domain 125 314 5.9E-60 T 28-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 A6A12_RS12160 d6050924a0bd69c700ccae845923fd6b 486 PIRSF PIRSF000774 1 486 1.9E-153 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A6A12_RS12160 d6050924a0bd69c700ccae845923fd6b 486 Gene3D G3DSA:1.10.10.10 332 419 1.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS12160 d6050924a0bd69c700ccae845923fd6b 486 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 373 392 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A6A12_RS12160 d6050924a0bd69c700ccae845923fd6b 486 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 464 471 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 A6A12_RS02265 5bb2f8b011b92a4b6a88735715c38730 480 Pfam PF06054 Competence protein CoiA-like family 31 72 5.9E-6 T 28-03-2018 IPR010330 Competence-induced protein CoiA-like A6A12_RS10830 30bf2c08e8123c1dc1342d141e96af4b 319 Gene3D G3DSA:3.90.226.10 1 289 8.4E-67 T 28-03-2018 A6A12_RS10830 30bf2c08e8123c1dc1342d141e96af4b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 172 185 3.9E-48 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS10830 30bf2c08e8123c1dc1342d141e96af4b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 116 134 3.9E-48 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS10830 30bf2c08e8123c1dc1342d141e96af4b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 200 209 3.9E-48 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS10830 30bf2c08e8123c1dc1342d141e96af4b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 137 153 3.9E-48 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS10830 30bf2c08e8123c1dc1342d141e96af4b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 156 169 3.9E-48 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS10830 30bf2c08e8123c1dc1342d141e96af4b 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 91 102 3.9E-48 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS10830 30bf2c08e8123c1dc1342d141e96af4b 319 SUPERFAMILY SSF52096 5 318 9.57E-104 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS10830 30bf2c08e8123c1dc1342d141e96af4b 319 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 6 151 9.3E-65 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS10830 30bf2c08e8123c1dc1342d141e96af4b 319 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 319 6.5E-163 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS10830 30bf2c08e8123c1dc1342d141e96af4b 319 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 319 50.612 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 A6A12_RS07565 0fd73b3f65a2b8dcd6aa289d56119e9d 344 SUPERFAMILY SSF81345 7 338 3.4E-85 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A6A12_RS07565 0fd73b3f65a2b8dcd6aa289d56119e9d 344 Gene3D G3DSA:1.10.3470.10 2 344 2.0E-76 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A6A12_RS07565 0fd73b3f65a2b8dcd6aa289d56119e9d 344 Pfam PF01032 FecCD transport family 17 337 2.2E-91 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A6A12_RS01625 0968c49ce789d7421c909a432ccced01 157 SUPERFAMILY SSF54523 7 135 3.14E-14 T 28-03-2018 A6A12_RS01625 0968c49ce789d7421c909a432ccced01 157 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 26 4.8E-10 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS01625 0968c49ce789d7421c909a432ccced01 157 Gene3D G3DSA:3.30.700.10 7 155 2.5E-19 T 28-03-2018 A6A12_RS01625 0968c49ce789d7421c909a432ccced01 157 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 26 6.1E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS14175 177588ae47da42adb68fd0156d01e23a 175 Gene3D G3DSA:1.20.1260.10 1 162 3.8E-42 T 28-03-2018 IPR012347 Ferritin-related A6A12_RS14175 177588ae47da42adb68fd0156d01e23a 175 SUPERFAMILY SSF47240 1 159 1.72E-58 T 28-03-2018 IPR009078 Ferritin-like superfamily A6A12_RS14175 177588ae47da42adb68fd0156d01e23a 175 Pfam PF00210 Ferritin-like domain 8 143 7.9E-39 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A6A12_RS10895 b232733e5e0efc21bf59aca2b536ec86 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 3.9E-76 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A6A12_RS10895 b232733e5e0efc21bf59aca2b536ec86 185 SUPERFAMILY SSF55194 2 184 3.92E-71 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 A6A12_RS10895 b232733e5e0efc21bf59aca2b536ec86 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.413 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 A6A12_RS10895 b232733e5e0efc21bf59aca2b536ec86 185 Pfam PF01765 Ribosome recycling factor 20 183 5.5E-62 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 A6A12_RS10895 b232733e5e0efc21bf59aca2b536ec86 185 Gene3D G3DSA:1.10.132.20 75 184 7.0E-37 T 28-03-2018 A6A12_RS10895 b232733e5e0efc21bf59aca2b536ec86 185 Gene3D G3DSA:1.10.132.20 2 74 4.8E-12 T 28-03-2018 A6A12_RS04275 002b19d7738fe590491ae6159eda0566 956 SUPERFAMILY SSF69318 250 491 7.67E-20 T 28-03-2018 A6A12_RS04275 002b19d7738fe590491ae6159eda0566 956 SUPERFAMILY SSF69318 679 751 7.67E-20 T 28-03-2018 A6A12_RS04275 002b19d7738fe590491ae6159eda0566 956 ProSitePatterns PS00018 EF-hand calcium-binding domain. 253 265 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site A6A12_RS04275 002b19d7738fe590491ae6159eda0566 956 Gene3D G3DSA:2.130.10.130 163 433 1.1E-8 T 28-03-2018 A6A12_RS04275 002b19d7738fe590491ae6159eda0566 956 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 315 374 4.0E-7 T 28-03-2018 A6A12_RS04275 002b19d7738fe590491ae6159eda0566 956 Gene3D G3DSA:2.100.10.30 542 646 1.8E-4 T 28-03-2018 A6A12_RS04275 002b19d7738fe590491ae6159eda0566 956 Gene3D G3DSA:2.100.10.30 861 956 3.8E-5 T 28-03-2018 A6A12_RS04275 002b19d7738fe590491ae6159eda0566 956 Pfam PF16458 Beta-prism lectin 820 953 2.8E-55 T 28-03-2018 IPR032496 Hemolysin, beta-prism lectin A6A12_RS04275 002b19d7738fe590491ae6159eda0566 956 Pfam PF16458 Beta-prism lectin 506 635 2.3E-57 T 28-03-2018 IPR032496 Hemolysin, beta-prism lectin A6A12_RS05715 60afade2c2b5648cb968371c5819ed25 426 Gene3D G3DSA:3.65.10.10 20 222 3.2E-62 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A6A12_RS05715 60afade2c2b5648cb968371c5819ed25 426 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 14 425 2.0E-140 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A6A12_RS05715 60afade2c2b5648cb968371c5819ed25 426 ProSitePatterns PS00104 EPSP synthase signature 1. 90 104 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A6A12_RS05715 60afade2c2b5648cb968371c5819ed25 426 PIRSF PIRSF000505 1 426 9.8E-155 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A6A12_RS05715 60afade2c2b5648cb968371c5819ed25 426 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 421 8.1E-152 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A6A12_RS05715 60afade2c2b5648cb968371c5819ed25 426 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 10 426 34.356 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A6A12_RS05715 60afade2c2b5648cb968371c5819ed25 426 Gene3D G3DSA:3.65.10.10 223 426 4.1E-69 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 A6A12_RS05715 60afade2c2b5648cb968371c5819ed25 426 ProSitePatterns PS00885 EPSP synthase signature 2. 339 357 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 A6A12_RS05715 60afade2c2b5648cb968371c5819ed25 426 SUPERFAMILY SSF55205 1 424 2.88E-143 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A6A12_RS00850 0839932f6152e6dfaa5ad550c98585df 128 SMART SM00363 8 72 2.1E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS00850 0839932f6152e6dfaa5ad550c98585df 128 PIRSF PIRSF016821 5 128 5.2E-41 T 28-03-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 A6A12_RS00850 0839932f6152e6dfaa5ad550c98585df 128 SUPERFAMILY SSF55174 7 105 8.15E-32 T 28-03-2018 A6A12_RS00850 0839932f6152e6dfaa5ad550c98585df 128 Pfam PF01479 S4 domain 9 54 8.7E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS00850 0839932f6152e6dfaa5ad550c98585df 128 Gene3D G3DSA:3.10.290.10 1 104 2.8E-25 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 A6A12_RS06930 fd34808b03692899f2017b5976d23539 257 PIRSF PIRSF028069 1 255 2.2E-95 T 28-03-2018 IPR016866 Uncharacterised conserved protein UCP028069 A6A12_RS06930 fd34808b03692899f2017b5976d23539 257 Pfam PF11932 Protein of unknown function (DUF3450) 10 248 3.1E-80 T 28-03-2018 IPR016866 Uncharacterised conserved protein UCP028069 A6A12_RS06710 4e1ae797941e10d985ef5c641d8d124f 325 PRINTS PR00605 Class IC cytochrome C signature 295 317 5.8E-6 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 A6A12_RS06710 4e1ae797941e10d985ef5c641d8d124f 325 PRINTS PR00605 Class IC cytochrome C signature 166 177 5.8E-6 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 A6A12_RS06710 4e1ae797941e10d985ef5c641d8d124f 325 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 115 323 8.2E-57 T 28-03-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III A6A12_RS06710 4e1ae797941e10d985ef5c641d8d124f 325 SUPERFAMILY SSF46626 243 322 1.4E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS06710 4e1ae797941e10d985ef5c641d8d124f 325 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 156 229 2.4E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS06710 4e1ae797941e10d985ef5c641d8d124f 325 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 243 317 1.4E-10 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS06710 4e1ae797941e10d985ef5c641d8d124f 325 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 37 83 2.4E-23 T 28-03-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal A6A12_RS06710 4e1ae797941e10d985ef5c641d8d124f 325 Gene3D G3DSA:1.10.760.10 142 244 6.8E-23 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS06710 4e1ae797941e10d985ef5c641d8d124f 325 Gene3D G3DSA:1.10.760.10 245 325 6.8E-17 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS06710 4e1ae797941e10d985ef5c641d8d124f 325 SUPERFAMILY SSF46626 55 78 4.22E-30 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS06710 4e1ae797941e10d985ef5c641d8d124f 325 SUPERFAMILY SSF46626 147 237 4.22E-30 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS06710 4e1ae797941e10d985ef5c641d8d124f 325 PIRSF PIRSF000006 1 324 4.5E-107 T 28-03-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III A6A12_RS01760 5d95ab04cc84c964599ab6b4f28fd3aa 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 6.6E-44 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01760 5d95ab04cc84c964599ab6b4f28fd3aa 103 SUPERFAMILY SSF141091 1 102 1.06E-38 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01760 5d95ab04cc84c964599ab6b4f28fd3aa 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.34 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01760 5d95ab04cc84c964599ab6b4f28fd3aa 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 3.0E-40 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01760 5d95ab04cc84c964599ab6b4f28fd3aa 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS14080 9403781d3021592037cc5323270e07d2 135 Pfam PF02416 mttA/Hcf106 family 4 34 1.4E-5 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A6A12_RS14080 9403781d3021592037cc5323270e07d2 135 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 4.7E-26 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A6A12_RS14080 9403781d3021592037cc5323270e07d2 135 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 4.7E-26 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A6A12_RS14080 9403781d3021592037cc5323270e07d2 135 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 4.7E-26 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 A6A12_RS14080 9403781d3021592037cc5323270e07d2 135 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 133 18.508 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 A6A12_RS14080 9403781d3021592037cc5323270e07d2 135 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 80 9.2E-34 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 A6A12_RS14080 9403781d3021592037cc5323270e07d2 135 Gene3D G3DSA:1.10.287.880 39 74 0.0011 T 28-03-2018 A6A12_RS06355 ce0a2844a43b6ad7968891dab5f9116b 310 SUPERFAMILY SSF46785 7 112 2.49E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS06355 ce0a2844a43b6ad7968891dab5f9116b 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 4.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS06355 ce0a2844a43b6ad7968891dab5f9116b 310 Gene3D G3DSA:3.40.190.10 89 176 1.5E-14 T 28-03-2018 A6A12_RS06355 ce0a2844a43b6ad7968891dab5f9116b 310 Pfam PF03466 LysR substrate binding domain 89 299 2.2E-40 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS06355 ce0a2844a43b6ad7968891dab5f9116b 310 SUPERFAMILY SSF53850 90 304 1.61E-38 T 28-03-2018 A6A12_RS06355 ce0a2844a43b6ad7968891dab5f9116b 310 Gene3D G3DSA:1.10.10.10 3 84 2.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS06355 ce0a2844a43b6ad7968891dab5f9116b 310 Gene3D G3DSA:3.40.190.10 177 264 5.1E-26 T 28-03-2018 A6A12_RS08910 6d490a41fac11728c06756687416aa65 225 SUPERFAMILY SSF161098 12 203 5.76E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS08910 6d490a41fac11728c06756687416aa65 225 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 112 3.9E-24 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A6A12_RS08910 6d490a41fac11728c06756687416aa65 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 216 1.6E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS08910 6d490a41fac11728c06756687416aa65 225 Gene3D G3DSA:1.10.3720.10 2 222 5.5E-41 T 28-03-2018 A6A12_RS01345 ee9ace90e8182bc283143de1e6f9e0fb 134 Gene3D G3DSA:3.40.1260.10 7 134 9.5E-25 T 28-03-2018 A6A12_RS01345 ee9ace90e8182bc283143de1e6f9e0fb 134 SUPERFAMILY SSF75169 9 134 3.14E-36 T 28-03-2018 IPR027396 DsrEFH-like A6A12_RS01345 ee9ace90e8182bc283143de1e6f9e0fb 134 Pfam PF02635 DsrE/DsrF-like family 8 134 3.0E-26 T 28-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein A6A12_RS01345 ee9ace90e8182bc283143de1e6f9e0fb 134 TIGRFAM TIGR03012 sulf_tusD_dsrE: sulfur relay protein TusD/DsrE 9 134 2.1E-53 T 28-03-2018 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 A6A12_RS04975 61ba47b9820a31c9152b92e9c4cf47e9 337 SUPERFAMILY SSF53774 3 336 1.7E-112 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A6A12_RS04975 61ba47b9820a31c9152b92e9c4cf47e9 337 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 4 336 3.6E-116 T 28-03-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 A6A12_RS04975 61ba47b9820a31c9152b92e9c4cf47e9 337 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 84 94 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A6A12_RS04975 61ba47b9820a31c9152b92e9c4cf47e9 337 PIRSF PIRSF500176 2 333 6.2E-108 T 28-03-2018 A6A12_RS04975 61ba47b9820a31c9152b92e9c4cf47e9 337 Pfam PF00710 Asparaginase, N-terminal 5 192 2.2E-66 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A6A12_RS04975 61ba47b9820a31c9152b92e9c4cf47e9 337 Gene3D G3DSA:3.40.50.1170 1 211 2.3E-84 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A6A12_RS04975 61ba47b9820a31c9152b92e9c4cf47e9 337 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 8 16 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A6A12_RS04975 61ba47b9820a31c9152b92e9c4cf47e9 337 PIRSF PIRSF001220 1 335 3.1E-93 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A6A12_RS04975 61ba47b9820a31c9152b92e9c4cf47e9 337 PRINTS PR00139 Asparaginase/glutaminase family signature 261 279 5.4E-16 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A6A12_RS04975 61ba47b9820a31c9152b92e9c4cf47e9 337 PRINTS PR00139 Asparaginase/glutaminase family signature 6 17 5.4E-16 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A6A12_RS04975 61ba47b9820a31c9152b92e9c4cf47e9 337 PRINTS PR00139 Asparaginase/glutaminase family signature 83 101 5.4E-16 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A6A12_RS04975 61ba47b9820a31c9152b92e9c4cf47e9 337 Gene3D G3DSA:3.40.50.40 212 337 2.6E-38 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 A6A12_RS04975 61ba47b9820a31c9152b92e9c4cf47e9 337 SMART SM00870 5 324 2.2E-137 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A6A12_RS10305 2b6fea3cc05ea1c1e24c9c48ead948d1 115 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 112 9.0E-32 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR A6A12_RS10305 2b6fea3cc05ea1c1e24c9c48ead948d1 115 Gene3D G3DSA:3.40.30.10 2 115 4.0E-38 T 28-03-2018 A6A12_RS10305 2b6fea3cc05ea1c1e24c9c48ead948d1 115 Pfam PF03960 ArsC family 6 113 5.3E-17 T 28-03-2018 IPR006660 Arsenate reductase-like A6A12_RS10305 2b6fea3cc05ea1c1e24c9c48ead948d1 115 SUPERFAMILY SSF52833 2 114 2.71E-35 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS06810 8c4909d4344e050759ac5ccb2afad72b 539 Gene3D G3DSA:3.30.565.10 360 532 6.8E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS06810 8c4909d4344e050759ac5ccb2afad72b 539 SMART SM00387 439 533 1.1E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS06810 8c4909d4344e050759ac5ccb2afad72b 539 Pfam PF07730 Histidine kinase 336 400 1.3E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 A6A12_RS06810 8c4909d4344e050759ac5ccb2afad72b 539 Pfam PF05231 MASE1 24 300 3.4E-30 T 28-03-2018 IPR007895 MASE1 A6A12_RS06810 8c4909d4344e050759ac5ccb2afad72b 539 SUPERFAMILY SSF55874 415 530 3.41E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS09855 b490cb77e41f3aeb1b34f324d43629f7 68 Pfam PF04995 Heme exporter protein D (CcmD) 13 55 2.5E-14 T 28-03-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 A6A12_RS09855 b490cb77e41f3aeb1b34f324d43629f7 68 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 10 56 2.1E-16 T 28-03-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 A6A12_RS05605 3294361b71e934ef487781034f3e3cad 205 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 9 194 5.0E-95 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 A6A12_RS05605 3294361b71e934ef487781034f3e3cad 205 Pfam PF04356 Protein of unknown function (DUF489) 7 195 1.7E-77 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 A6A12_RS05605 3294361b71e934ef487781034f3e3cad 205 SUPERFAMILY SSF101322 2 204 2.88E-80 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 A6A12_RS05605 3294361b71e934ef487781034f3e3cad 205 Gene3D G3DSA:1.10.3890.10 4 203 3.1E-81 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 A6A12_RS05605 3294361b71e934ef487781034f3e3cad 205 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 1 203 36.145 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 A6A12_RS01770 97940531aabdeb56decc4769c0a416b5 390 Pfam PF01926 50S ribosome-binding GTPase 161 284 7.4E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS01770 97940531aabdeb56decc4769c0a416b5 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 1.0E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS01770 97940531aabdeb56decc4769c0a416b5 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 1.0E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS01770 97940531aabdeb56decc4769c0a416b5 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 1.0E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS01770 97940531aabdeb56decc4769c0a416b5 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 1.0E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 A6A12_RS01770 97940531aabdeb56decc4769c0a416b5 390 Hamap MF_01454 GTPase Obg [obg]. 2 333 46.324 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A6A12_RS01770 97940531aabdeb56decc4769c0a416b5 390 PIRSF PIRSF002401 1 374 5.6E-135 T 28-03-2018 IPR035101 GTP-binding protein, Obg-type A6A12_RS01770 97940531aabdeb56decc4769c0a416b5 390 SUPERFAMILY SSF52540 151 344 2.12E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01770 97940531aabdeb56decc4769c0a416b5 390 SUPERFAMILY SSF82051 2 157 1.44E-54 T 28-03-2018 IPR006169 GTP1/OBG domain A6A12_RS01770 97940531aabdeb56decc4769c0a416b5 390 Pfam PF01018 GTP1/OBG 4 156 2.2E-55 T 28-03-2018 IPR006169 GTP1/OBG domain A6A12_RS01770 97940531aabdeb56decc4769c0a416b5 390 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 332 9.9E-141 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 A6A12_RS01770 97940531aabdeb56decc4769c0a416b5 390 Gene3D G3DSA:2.70.210.12 2 156 7.0E-54 T 28-03-2018 IPR006169 GTP1/OBG domain A6A12_RS01770 97940531aabdeb56decc4769c0a416b5 390 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 A6A12_RS01770 97940531aabdeb56decc4769c0a416b5 390 Gene3D G3DSA:3.40.50.300 159 344 4.3E-31 T 28-03-2018 A6A12_RS13625 1167f7927879b3633103f08915a00170 82 Pfam PF12728 Helix-turn-helix domain 24 73 5.5E-11 T 28-03-2018 A6A12_RS13625 1167f7927879b3633103f08915a00170 82 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 24 70 1.3E-11 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A6A12_RS13625 1167f7927879b3633103f08915a00170 82 Gene3D G3DSA:1.10.10.10 23 79 1.5E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS04705 6e7c85280a27c50b721a89ffd0c15639 437 Gene3D G3DSA:1.20.1250.20 210 405 6.0E-10 T 28-03-2018 A6A12_RS04705 6e7c85280a27c50b721a89ffd0c15639 437 Gene3D G3DSA:1.20.1250.20 9 209 4.8E-29 T 28-03-2018 A6A12_RS04705 6e7c85280a27c50b721a89ffd0c15639 437 Pfam PF05977 Transmembrane secretion effector 16 394 2.1E-29 T 28-03-2018 IPR010290 Transmembrane secretion effector A6A12_RS04705 6e7c85280a27c50b721a89ffd0c15639 437 SUPERFAMILY SSF103473 15 405 1.57E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain A6A12_RS07315 484095af814e16e61691bd963290765f 193 Pfam PF13302 Acetyltransferase (GNAT) domain 18 162 3.8E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A6A12_RS07315 484095af814e16e61691bd963290765f 193 Gene3D G3DSA:3.40.630.30 3 193 1.2E-23 T 28-03-2018 A6A12_RS07315 484095af814e16e61691bd963290765f 193 SUPERFAMILY SSF55729 15 186 3.54E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS04760 24f0dda3ed3be077ccdd310b6734eaeb 296 SUPERFAMILY SSF142338 7 291 1.96E-84 T 28-03-2018 A6A12_RS04760 24f0dda3ed3be077ccdd310b6734eaeb 296 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 9 271 6.9E-104 T 28-03-2018 IPR010119 Gluconeogenesis factor A6A12_RS04760 24f0dda3ed3be077ccdd310b6734eaeb 296 Hamap MF_00973 Gluconeogenesis factor. 5 296 30.399 T 28-03-2018 IPR010119 Gluconeogenesis factor A6A12_RS04760 24f0dda3ed3be077ccdd310b6734eaeb 296 Gene3D G3DSA:3.40.50.10680 86 296 9.1E-41 T 28-03-2018 A6A12_RS04760 24f0dda3ed3be077ccdd310b6734eaeb 296 Pfam PF01933 Uncharacterised protein family UPF0052 9 285 1.7E-75 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 A6A12_RS03290 f59c207e2344900fe075039d13634734 783 Pfam PF00990 Diguanylate cyclase, GGDEF domain 339 503 9.0E-42 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS03290 f59c207e2344900fe075039d13634734 783 SMART SM00052 517 760 3.6E-68 T 28-03-2018 IPR001633 EAL domain A6A12_RS03290 f59c207e2344900fe075039d13634734 783 SMART SM00267 328 507 5.8E-44 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS03290 f59c207e2344900fe075039d13634734 783 Gene3D G3DSA:3.20.20.450 515 774 9.6E-75 T 28-03-2018 IPR001633 EAL domain A6A12_RS03290 f59c207e2344900fe075039d13634734 783 SUPERFAMILY SSF141868 522 769 1.57E-68 T 28-03-2018 IPR001633 EAL domain A6A12_RS03290 f59c207e2344900fe075039d13634734 783 Pfam PF00563 EAL domain 523 755 6.6E-61 T 28-03-2018 IPR001633 EAL domain A6A12_RS03290 f59c207e2344900fe075039d13634734 783 SUPERFAMILY SSF55073 344 509 4.39E-38 T 28-03-2018 IPR029787 Nucleotide cyclase A6A12_RS03290 f59c207e2344900fe075039d13634734 783 SUPERFAMILY SSF158472 281 330 6.93E-5 T 28-03-2018 A6A12_RS03290 f59c207e2344900fe075039d13634734 783 Gene3D G3DSA:3.30.70.270 333 514 8.6E-48 T 28-03-2018 A6A12_RS03290 f59c207e2344900fe075039d13634734 783 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 338 506 2.8E-34 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS04595 f83a13337030bc130b5ea239792a2358 421 Gene3D G3DSA:3.40.1190.10 2 288 5.5E-72 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS04595 f83a13337030bc130b5ea239792a2358 421 SUPERFAMILY SSF53623 13 286 3.01E-84 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS04595 f83a13337030bc130b5ea239792a2358 421 SUPERFAMILY SSF53244 289 418 7.69E-32 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A6A12_RS04595 f83a13337030bc130b5ea239792a2358 421 Gene3D G3DSA:3.90.190.20 289 420 3.1E-29 T 28-03-2018 A6A12_RS04595 f83a13337030bc130b5ea239792a2358 421 PIRSF PIRSF001563 7 420 4.3E-104 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A6A12_RS04595 f83a13337030bc130b5ea239792a2358 421 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 144 159 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 A6A12_RS04595 f83a13337030bc130b5ea239792a2358 421 TIGRFAM TIGR01499 folC: bifunctional protein FolC 32 415 1.8E-102 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 A6A12_RS04595 f83a13337030bc130b5ea239792a2358 421 Pfam PF08245 Mur ligase middle domain 54 193 2.2E-7 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 A6A12_RS04595 f83a13337030bc130b5ea239792a2358 421 Pfam PF02875 Mur ligase family, glutamate ligase domain 288 348 6.9E-8 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 A6A12_RS13425 1a49592699ba2f8f39dce3f30a49d617 589 Gene3D G3DSA:3.20.20.370 309 583 5.6E-45 T 28-03-2018 A6A12_RS13425 1a49592699ba2f8f39dce3f30a49d617 589 Gene3D G3DSA:3.40.50.2000 162 303 6.2E-8 T 28-03-2018 A6A12_RS13425 1a49592699ba2f8f39dce3f30a49d617 589 Pfam PF13439 Glycosyltransferase Family 4 13 158 9.5E-21 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A6A12_RS13425 1a49592699ba2f8f39dce3f30a49d617 589 Gene3D G3DSA:3.40.50.2000 1 161 1.9E-10 T 28-03-2018 A6A12_RS13425 1a49592699ba2f8f39dce3f30a49d617 589 SUPERFAMILY SSF53756 3 337 3.86E-30 T 28-03-2018 A6A12_RS13425 1a49592699ba2f8f39dce3f30a49d617 589 SUPERFAMILY SSF88713 366 549 2.67E-38 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A6A12_RS13425 1a49592699ba2f8f39dce3f30a49d617 589 Pfam PF01522 Polysaccharide deacetylase 405 542 1.1E-31 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A6A12_RS12865 03309e71822f16b64c1174c724e5c84d 257 SUPERFAMILY SSF51351 2 251 3.4E-88 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS12865 03309e71822f16b64c1174c724e5c84d 257 ProSitePatterns PS00171 Triosephosphate isomerase active site. 167 177 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS12865 03309e71822f16b64c1174c724e5c84d 257 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 251 39.239 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS12865 03309e71822f16b64c1174c724e5c84d 257 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 241 2.4E-78 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS12865 03309e71822f16b64c1174c724e5c84d 257 Gene3D G3DSA:3.20.20.70 1 257 3.6E-95 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS12865 03309e71822f16b64c1174c724e5c84d 257 Pfam PF00121 Triosephosphate isomerase 5 247 2.6E-85 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS13220 0d7f4864742db3a4de46111eb6a1cd83 396 Gene3D G3DSA:1.10.287.70 1 371 0.0019 T 28-03-2018 A6A12_RS03450 44a73e5b07a1fe6bc0c2935dd16c2806 436 Pfam PF00463 Isocitrate lyase family 14 257 2.8E-61 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A6A12_RS03450 44a73e5b07a1fe6bc0c2935dd16c2806 436 Pfam PF00463 Isocitrate lyase family 258 436 3.7E-52 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A6A12_RS03450 44a73e5b07a1fe6bc0c2935dd16c2806 436 SUPERFAMILY SSF51621 6 436 8.52E-151 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A6A12_RS03450 44a73e5b07a1fe6bc0c2935dd16c2806 436 PIRSF PIRSF001362 1 436 4.2E-223 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A6A12_RS03450 44a73e5b07a1fe6bc0c2935dd16c2806 436 ProSitePatterns PS00161 Isocitrate lyase signature. 195 200 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 A6A12_RS03450 44a73e5b07a1fe6bc0c2935dd16c2806 436 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 258 436 3.1E-89 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A6A12_RS03450 44a73e5b07a1fe6bc0c2935dd16c2806 436 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 10 257 2.9E-113 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 A6A12_RS03450 44a73e5b07a1fe6bc0c2935dd16c2806 436 Gene3D G3DSA:3.20.20.60 1 419 1.0E-148 T 28-03-2018 A6A12_RS08110 30d8f1833b5956d583643fc9ea691b04 391 Gene3D G3DSA:3.40.50.20 1 120 6.0E-21 T 28-03-2018 A6A12_RS08110 30d8f1833b5956d583643fc9ea691b04 391 Pfam PF02222 ATP-grasp domain 121 293 9.1E-56 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A6A12_RS08110 30d8f1833b5956d583643fc9ea691b04 391 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 12 389 2.3E-191 T 28-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A6A12_RS08110 30d8f1833b5956d583643fc9ea691b04 391 Pfam PF01370 NAD dependent epimerase/dehydratase family 17 79 8.9E-5 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A6A12_RS08110 30d8f1833b5956d583643fc9ea691b04 391 SUPERFAMILY SSF51246 317 389 2.35E-17 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A6A12_RS08110 30d8f1833b5956d583643fc9ea691b04 391 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 6 390 51.396 T 28-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A6A12_RS08110 30d8f1833b5956d583643fc9ea691b04 391 Gene3D G3DSA:3.30.470.20 195 389 1.0E-35 T 28-03-2018 A6A12_RS08110 30d8f1833b5956d583643fc9ea691b04 391 SUPERFAMILY SSF56059 111 313 1.41E-55 T 28-03-2018 A6A12_RS08110 30d8f1833b5956d583643fc9ea691b04 391 SUPERFAMILY SSF52440 2 110 4.75E-35 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A6A12_RS08110 30d8f1833b5956d583643fc9ea691b04 391 Gene3D G3DSA:3.30.1490.20 127 194 3.9E-18 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A6A12_RS12155 5142a3fa770e7278c8fc370300b4e1c5 241 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 4 241 2.8E-126 T 28-03-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 A6A12_RS12155 5142a3fa770e7278c8fc370300b4e1c5 241 SMART SM00382 28 202 1.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS12155 5142a3fa770e7278c8fc370300b4e1c5 241 SUPERFAMILY SSF52540 3 237 1.09E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS12155 5142a3fa770e7278c8fc370300b4e1c5 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 214 236 1.3E-8 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal A6A12_RS12155 5142a3fa770e7278c8fc370300b4e1c5 241 Gene3D G3DSA:3.40.50.300 1 238 8.7E-63 T 28-03-2018 A6A12_RS12155 5142a3fa770e7278c8fc370300b4e1c5 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS12155 5142a3fa770e7278c8fc370300b4e1c5 241 Pfam PF00005 ABC transporter 20 166 2.1E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS10650 943f8cd7c58e0beda01ebcda2600de57 131 PIRSF PIRSF002889 1 131 1.1E-33 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 A6A12_RS10650 943f8cd7c58e0beda01ebcda2600de57 131 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 5 129 1.7E-28 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 A6A12_RS01510 abadf6a1dd5e1f862ce73b0f1a8fa286 426 Pfam PF00999 Sodium/hydrogen exchanger family 31 415 3.1E-54 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A6A12_RS01975 98f723ef297503d2d80aeeb2280f9f61 669 SUPERFAMILY SSF52518 10 324 2.07E-120 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS01975 98f723ef297503d2d80aeeb2280f9f61 669 Pfam PF02779 Transketolase, pyrimidine binding domain 359 529 6.9E-48 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A6A12_RS01975 98f723ef297503d2d80aeeb2280f9f61 669 Pfam PF02780 Transketolase, C-terminal domain 549 660 2.8E-20 T 28-03-2018 IPR033248 Transketolase, C-terminal domain A6A12_RS01975 98f723ef297503d2d80aeeb2280f9f61 669 SMART SM00861 359 530 1.9E-67 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain A6A12_RS01975 98f723ef297503d2d80aeeb2280f9f61 669 Gene3D G3DSA:3.40.50.920 546 669 3.0E-32 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A6A12_RS01975 98f723ef297503d2d80aeeb2280f9f61 669 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 9 338 1.2E-166 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A6A12_RS01975 98f723ef297503d2d80aeeb2280f9f61 669 ProSitePatterns PS00802 Transketolase signature 2. 472 488 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A6A12_RS01975 98f723ef297503d2d80aeeb2280f9f61 669 SUPERFAMILY SSF52922 537 669 1.57E-44 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 A6A12_RS01975 98f723ef297503d2d80aeeb2280f9f61 669 ProSitePatterns PS00801 Transketolase signature 1. 17 37 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 A6A12_RS01975 98f723ef297503d2d80aeeb2280f9f61 669 Gene3D G3DSA:3.40.50.970 369 545 9.4E-43 T 28-03-2018 A6A12_RS01975 98f723ef297503d2d80aeeb2280f9f61 669 SUPERFAMILY SSF52518 339 531 1.77E-68 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold A6A12_RS01975 98f723ef297503d2d80aeeb2280f9f61 669 TIGRFAM TIGR00232 tktlase_bact: transketolase 10 668 0.0 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 A6A12_RS01975 98f723ef297503d2d80aeeb2280f9f61 669 Gene3D G3DSA:3.40.50.970 1 368 3.8E-127 T 28-03-2018 A6A12_RS04465 e1d05a899c160d8749e039b6223a2301 370 Gene3D G3DSA:2.40.160.10 12 370 1.1E-36 T 28-03-2018 A6A12_RS04465 e1d05a899c160d8749e039b6223a2301 370 SUPERFAMILY SSF56935 27 370 1.63E-36 T 28-03-2018 A6A12_RS04465 e1d05a899c160d8749e039b6223a2301 370 Pfam PF00267 Gram-negative porin 29 370 1.1E-5 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 A6A12_RS03815 0e002ce5f1103f4f4d23c34094a3ad93 58 Gene3D G3DSA:1.10.10.10 5 58 3.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03815 0e002ce5f1103f4f4d23c34094a3ad93 58 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 51 2.3E-14 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A6A12_RS03815 0e002ce5f1103f4f4d23c34094a3ad93 58 SUPERFAMILY SSF46955 5 54 7.69E-8 T 28-03-2018 IPR009061 Putative DNA-binding domain A6A12_RS03815 0e002ce5f1103f4f4d23c34094a3ad93 58 Pfam PF12728 Helix-turn-helix domain 6 54 3.5E-19 T 28-03-2018 A6A12_RS08175 ade730a150bfa43691d8f9143585146f 185 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A6A12_RS08175 ade730a150bfa43691d8f9143585146f 185 PIRSF PIRSF000847 1 183 1.1E-44 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A6A12_RS08175 ade730a150bfa43691d8f9143585146f 185 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 71 1.4E-17 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A6A12_RS08175 ade730a150bfa43691d8f9143585146f 185 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 180 3.9E-53 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A6A12_RS12785 d539b3582565b78756d4abd41a4ef3e2 144 Pfam PF00581 Rhodanese-like domain 47 135 5.8E-18 T 28-03-2018 IPR001763 Rhodanese-like domain A6A12_RS12785 d539b3582565b78756d4abd41a4ef3e2 144 Gene3D G3DSA:3.40.250.10 21 144 8.5E-25 T 28-03-2018 IPR001763 Rhodanese-like domain A6A12_RS12785 d539b3582565b78756d4abd41a4ef3e2 144 SMART SM00450 40 138 1.6E-20 T 28-03-2018 IPR001763 Rhodanese-like domain A6A12_RS12785 d539b3582565b78756d4abd41a4ef3e2 144 SUPERFAMILY SSF52821 16 142 5.5E-30 T 28-03-2018 IPR001763 Rhodanese-like domain A6A12_RS07250 190c9776d09f58e1035d6aacb0babc44 485 Gene3D G3DSA:3.40.50.300 243 484 1.7E-46 T 28-03-2018 A6A12_RS07250 190c9776d09f58e1035d6aacb0babc44 485 SMART SM00490 278 359 1.5E-30 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS07250 190c9776d09f58e1035d6aacb0babc44 485 Hamap MF_00968 ATP-dependent RNA helicase RhlE [rhlE]. 22 479 50.066 T 28-03-2018 IPR028622 ATP-dependent RNA helicase RhlE GO:0004004|GO:0042255 A6A12_RS07250 190c9776d09f58e1035d6aacb0babc44 485 SUPERFAMILY SSF52540 94 380 9.07E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS07250 190c9776d09f58e1035d6aacb0babc44 485 Gene3D G3DSA:3.40.50.300 30 242 2.2E-61 T 28-03-2018 A6A12_RS07250 190c9776d09f58e1035d6aacb0babc44 485 Pfam PF00271 Helicase conserved C-terminal domain 251 359 3.8E-27 T 28-03-2018 IPR001650 Helicase, C-terminal A6A12_RS07250 190c9776d09f58e1035d6aacb0babc44 485 Pfam PF00270 DEAD/DEAH box helicase 47 215 1.6E-49 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A6A12_RS07250 190c9776d09f58e1035d6aacb0babc44 485 SMART SM00487 41 242 2.0E-64 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS07250 190c9776d09f58e1035d6aacb0babc44 485 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 173 181 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A6A12_RS07665 3183b2e6cc8c89413b4c887fc59719d0 378 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 378 3.8E-139 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A6A12_RS07665 3183b2e6cc8c89413b4c887fc59719d0 378 PIRSF PIRSF000267 2 377 1.0E-110 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A6A12_RS07665 3183b2e6cc8c89413b4c887fc59719d0 378 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 361 7.4E-94 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 Pfam PF00009 Elongation factor Tu GTP binding domain 8 199 6.2E-57 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 Pfam PF03144 Elongation factor Tu domain 2 223 293 1.0E-9 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 SUPERFAMILY SSF54980 306 391 1.22E-15 T 28-03-2018 IPR035647 EF-G domain III/V-like A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 Gene3D G3DSA:3.30.70.240 405 485 9.5E-19 T 28-03-2018 A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 Gene3D G3DSA:2.40.30.10 192 304 1.6E-23 T 28-03-2018 A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 Gene3D G3DSA:3.40.50.300 72 191 3.0E-30 T 28-03-2018 A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 9 603 2.7E-289 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 SUPERFAMILY SSF52540 5 211 1.91E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 SUPERFAMILY SSF54980 402 516 6.71E-27 T 28-03-2018 IPR035647 EF-G domain III/V-like A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 Gene3D G3DSA:2.40.50.250 487 577 1.2E-38 T 28-03-2018 A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 154 5.2E-24 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 SUPERFAMILY SSF50447 155 301 2.08E-32 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 PRINTS PR00315 GTP-binding elongation factor signature 75 85 1.7E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 PRINTS PR00315 GTP-binding elongation factor signature 91 102 1.7E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 PRINTS PR00315 GTP-binding elongation factor signature 55 63 1.7E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 PRINTS PR00315 GTP-binding elongation factor signature 11 24 1.7E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 PRINTS PR00315 GTP-binding elongation factor signature 127 136 1.7E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 Pfam PF00679 Elongation factor G C-terminus 400 477 6.1E-21 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 Gene3D G3DSA:3.40.50.300 3 71 1.7E-10 T 28-03-2018 A6A12_RS00815 077e23e1a13993b09f1f36a71f941a92 607 Gene3D G3DSA:3.30.70.870 306 404 1.5E-33 T 28-03-2018 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 311 330 5.7E-95 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 275 295 5.7E-95 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 160 182 5.7E-95 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 245 265 5.7E-95 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 295 311 5.7E-95 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 5.7E-95 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 211 237 5.7E-95 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 5.7E-95 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 642 1.9E-261 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 316 639 1.2E-125 T 28-03-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 Pfam PF01578 Cytochrome C assembly protein 89 297 2.5E-54 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 190 205 6.4E-61 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 6.4E-61 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 395 414 6.4E-61 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 352 369 6.4E-61 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 6.4E-61 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 314 329 6.4E-61 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09845 b565692e83fe2a0ae773e336862f154f 651 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 632 645 6.4E-61 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS10670 fbe60bf30abcb5d28cf05dbb6bdd9c01 106 SUPERFAMILY SSF101498 2 99 5.62E-21 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 A6A12_RS10670 fbe60bf30abcb5d28cf05dbb6bdd9c01 106 Gene3D G3DSA:1.10.287.1160 69 97 1.5E-13 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 A6A12_RS10670 fbe60bf30abcb5d28cf05dbb6bdd9c01 106 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 4 100 3.3E-24 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 A6A12_RS10670 fbe60bf30abcb5d28cf05dbb6bdd9c01 106 Pfam PF04316 Anti-sigma-28 factor, FlgM 43 96 2.5E-17 T 28-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal A6A12_RS12825 a0dc5da1f7b2c259448670db8182ad31 157 Pfam PF02308 MgtC family 18 140 8.5E-30 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A6A12_RS12825 a0dc5da1f7b2c259448670db8182ad31 157 PRINTS PR01837 MgtC/SapB protein signature 21 40 7.9E-32 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A6A12_RS12825 a0dc5da1f7b2c259448670db8182ad31 157 PRINTS PR01837 MgtC/SapB protein signature 67 89 7.9E-32 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A6A12_RS12825 a0dc5da1f7b2c259448670db8182ad31 157 PRINTS PR01837 MgtC/SapB protein signature 94 118 7.9E-32 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A6A12_RS12825 a0dc5da1f7b2c259448670db8182ad31 157 PRINTS PR01837 MgtC/SapB protein signature 40 58 7.9E-32 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 A6A12_RS12665 bfef502d514fb69a1739d7c0bf897754 276 Gene3D G3DSA:1.10.1020.10 57 153 6.2E-33 T 28-03-2018 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 A6A12_RS12665 bfef502d514fb69a1739d7c0bf897754 276 PIRSF PIRSF000398 1 273 3.5E-74 T 28-03-2018 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 A6A12_RS12665 bfef502d514fb69a1739d7c0bf897754 276 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 10 252 8.0E-71 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 A6A12_RS12665 bfef502d514fb69a1739d7c0bf897754 276 Gene3D G3DSA:3.40.50.150 154 271 3.5E-16 T 28-03-2018 A6A12_RS12665 bfef502d514fb69a1739d7c0bf897754 276 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 178 184 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A6A12_RS12665 bfef502d514fb69a1739d7c0bf897754 276 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 10 26 6.5E-18 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 A6A12_RS12665 bfef502d514fb69a1739d7c0bf897754 276 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 175 187 6.5E-18 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 A6A12_RS12665 bfef502d514fb69a1739d7c0bf897754 276 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 31 45 6.5E-18 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 A6A12_RS12665 bfef502d514fb69a1739d7c0bf897754 276 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 50 63 6.5E-18 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 A6A12_RS12665 bfef502d514fb69a1739d7c0bf897754 276 SUPERFAMILY SSF53335 5 268 7.2E-76 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS12665 bfef502d514fb69a1739d7c0bf897754 276 TIGRFAM TIGR00571 dam: DNA adenine methylase 5 268 1.6E-94 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 A6A12_RS10680 25a49f5a63df839006975f9f23214837 143 Pfam PF02169 LPP20 lipoprotein 22 118 1.4E-8 T 28-03-2018 IPR024952 Lipoprotein LPP20-like A6A12_RS10680 25a49f5a63df839006975f9f23214837 143 PIRSF PIRSF028687 1 143 1.9E-59 T 28-03-2018 IPR007293 Flagellar protein FlgP A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 SMART SM00760 366 435 3.4E-45 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 SUPERFAMILY SSF48295 354 457 6.54E-38 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 Gene3D G3DSA:1.10.1750.10 361 457 3.2E-36 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 Gene3D G3DSA:3.40.50.300 120 287 7.7E-23 T 28-03-2018 A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 Pfam PF11638 DnaA N-terminal domain 1 56 1.0E-15 T 28-03-2018 IPR024633 DnaA N-terminal domain A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 1 456 2.3E-185 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 SMART SM00382 155 368 3.3E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 Gene3D G3DSA:1.10.8.60 289 360 4.4E-29 T 28-03-2018 A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 2 457 33.035 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 ProSitePatterns PS01008 DnaA protein signature. 416 435 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 SUPERFAMILY SSF52540 123 334 8.63E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 188 202 1.3E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 156 176 1.3E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 220 234 1.3E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 254 281 1.3E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 416 435 1.3E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 367 435 1.7E-32 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 A6A12_RS00005 6c8db62f4337eecd5568ebfa057f5c08 458 Pfam PF00308 Bacterial dnaA protein 124 340 1.7E-97 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA A6A12_RS04845 2bbe9904a0e66439ec8ba4c22fbce0e1 431 Gene3D G3DSA:2.40.160.60 33 431 6.7E-73 T 28-03-2018 A6A12_RS04845 2bbe9904a0e66439ec8ba4c22fbce0e1 431 SUPERFAMILY SSF56935 34 431 5.49E-88 T 28-03-2018 A6A12_RS04845 2bbe9904a0e66439ec8ba4c22fbce0e1 431 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 25 431 2.9E-124 T 28-03-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) A6A12_RS03250 b9168e487ba8c4f4c1191610c0361db1 559 Pfam PF06580 Histidine kinase 366 444 1.3E-26 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 A6A12_RS03250 b9168e487ba8c4f4c1191610c0361db1 559 SUPERFAMILY SSF55781 231 351 5.15E-8 T 28-03-2018 IPR029016 GAF domain-like A6A12_RS03250 b9168e487ba8c4f4c1191610c0361db1 559 Pfam PF07694 5TMR of 5TMR-LYT 25 194 4.5E-59 T 28-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 A6A12_RS03250 b9168e487ba8c4f4c1191610c0361db1 559 Gene3D G3DSA:3.30.450.40 164 378 4.3E-6 T 28-03-2018 IPR029016 GAF domain-like A6A12_RS03250 b9168e487ba8c4f4c1191610c0361db1 559 SUPERFAMILY SSF55874 420 533 1.31E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS03250 b9168e487ba8c4f4c1191610c0361db1 559 Gene3D G3DSA:3.30.565.10 380 555 1.2E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain A6A12_RS03250 b9168e487ba8c4f4c1191610c0361db1 559 Pfam PF13492 GAF domain 243 351 1.9E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 A6A12_RS07165 d154da3719b31b1b7d07f6b95fcd9922 160 SUPERFAMILY SSF56925 17 159 4.71E-21 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A6A12_RS07165 d154da3719b31b1b7d07f6b95fcd9922 160 Gene3D G3DSA:2.40.160.20 5 160 1.7E-14 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A6A12_RS07165 d154da3719b31b1b7d07f6b95fcd9922 160 Pfam PF13505 Outer membrane protein beta-barrel domain 5 159 4.3E-16 T 28-03-2018 IPR027385 Outer membrane protein beta-barrel A6A12_RS02815 5080d084153a083686eb3b97b3eba1e2 291 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 6 283 1.8E-41 T 28-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 A6A12_RS02815 5080d084153a083686eb3b97b3eba1e2 291 Gene3D G3DSA:3.30.420.40 128 270 5.4E-27 T 28-03-2018 A6A12_RS02815 5080d084153a083686eb3b97b3eba1e2 291 SUPERFAMILY SSF53067 1 111 2.25E-25 T 28-03-2018 A6A12_RS02815 5080d084153a083686eb3b97b3eba1e2 291 Gene3D G3DSA:3.30.420.40 2 127 3.8E-19 T 28-03-2018 A6A12_RS02815 5080d084153a083686eb3b97b3eba1e2 291 SUPERFAMILY SSF53067 114 283 5.38E-44 T 28-03-2018 A6A12_RS09315 3f7c755439e27f78e4e14c2e28b9c855 206 Pfam PF11659 Protein of unknown function (DUF3261) 52 196 5.4E-33 T 28-03-2018 IPR021675 Protein of unknown function DUF3261 A6A12_RS12780 515713e6cf57dc9753a82edf7d59dd96 155 Gene3D G3DSA:3.10.420.10 3 155 7.7E-53 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A6A12_RS12780 515713e6cf57dc9753a82edf7d59dd96 155 Pfam PF02556 Preprotein translocase subunit SecB 7 146 1.7E-54 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A6A12_RS12780 515713e6cf57dc9753a82edf7d59dd96 155 Hamap MF_00821 Protein-export protein SecB [secB]. 1 147 31.738 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A6A12_RS12780 515713e6cf57dc9753a82edf7d59dd96 155 SUPERFAMILY SSF54611 3 143 5.23E-51 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A6A12_RS12780 515713e6cf57dc9753a82edf7d59dd96 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 125 143 1.9E-38 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A6A12_RS12780 515713e6cf57dc9753a82edf7d59dd96 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 75 95 1.9E-38 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A6A12_RS12780 515713e6cf57dc9753a82edf7d59dd96 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 15 32 1.9E-38 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A6A12_RS12780 515713e6cf57dc9753a82edf7d59dd96 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 99 121 1.9E-38 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A6A12_RS12780 515713e6cf57dc9753a82edf7d59dd96 155 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 9 146 2.0E-57 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 A6A12_RS12000 c0935ef0c78546fde24ba52fd4d7c3d8 173 Pfam PF06271 RDD family 23 163 5.4E-17 T 28-03-2018 IPR010432 RDD A6A12_RS09415 cbf4270c5c5b072863f6c9c39c54a168 545 Pfam PF00884 Sulfatase 241 529 5.4E-50 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 A6A12_RS09415 cbf4270c5c5b072863f6c9c39c54a168 545 Pfam PF08019 Domain of unknown function (DUF1705) 58 209 6.0E-46 T 28-03-2018 IPR012549 Phosphoethanolamine transferase, N-terminal GO:0016021 A6A12_RS09415 cbf4270c5c5b072863f6c9c39c54a168 545 SUPERFAMILY SSF53649 241 533 2.13E-20 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 A6A12_RS09415 cbf4270c5c5b072863f6c9c39c54a168 545 Gene3D G3DSA:3.40.720.10 239 540 4.8E-25 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 A6A12_RS08745 23f4813310d4626edeac0760f7e5b7eb 149 ProDom PD090021 MEMBRANE YGAW TRANSMEMBRANE INNER VV2263 Y3636 VC1828 VP1070 15 142 6.0E-62 T 28-03-2018 IPR010574 L-alanine exporter AlaE GO:0016021|GO:0034639 A6A12_RS08745 23f4813310d4626edeac0760f7e5b7eb 149 Hamap MF_00914 L-alanine exporter AlaE [alaE]. 2 145 30.547 T 28-03-2018 IPR010574 L-alanine exporter AlaE GO:0016021|GO:0034639 A6A12_RS08745 23f4813310d4626edeac0760f7e5b7eb 149 Pfam PF06610 L-alanine exporter 8 142 8.5E-67 T 28-03-2018 IPR010574 L-alanine exporter AlaE GO:0016021|GO:0034639 A6A12_RS02680 c18291600bc56c2e03de679ffa26370c 555 Pfam PF01740 STAS domain 445 537 1.3E-10 T 28-03-2018 IPR002645 STAS domain A6A12_RS02680 c18291600bc56c2e03de679ffa26370c 555 Gene3D G3DSA:3.30.750.24 432 555 1.0E-12 T 28-03-2018 IPR002645 STAS domain A6A12_RS02680 c18291600bc56c2e03de679ffa26370c 555 Pfam PF00916 Sulfate permease family 16 381 1.1E-80 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 A6A12_RS02680 c18291600bc56c2e03de679ffa26370c 555 SUPERFAMILY SSF52091 444 545 5.49E-10 T 28-03-2018 IPR002645 STAS domain A6A12_RS06145 2761191b7bf672fc0da0e6dd28c52c46 377 SUPERFAMILY SSF50621 212 357 5.23E-22 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A6A12_RS06145 2761191b7bf672fc0da0e6dd28c52c46 377 SUPERFAMILY SSF51419 14 243 2.83E-41 T 28-03-2018 IPR029066 PLP-binding barrel A6A12_RS06145 2761191b7bf672fc0da0e6dd28c52c46 377 PIRSF PIRSF038941 1 372 1.8E-128 T 28-03-2018 IPR005730 Carboxynorspermidine decarboxylase GO:0016831|GO:0045312 KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 A6A12_RS06145 2761191b7bf672fc0da0e6dd28c52c46 377 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 244 327 2.5E-4 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 A6A12_RS06145 2761191b7bf672fc0da0e6dd28c52c46 377 Gene3D G3DSA:2.40.37.10 239 370 1.3E-19 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 A6A12_RS06145 2761191b7bf672fc0da0e6dd28c52c46 377 TIGRFAM TIGR01047 nspC: carboxynorspermidine decarboxylase 6 370 8.1E-163 T 28-03-2018 IPR005730 Carboxynorspermidine decarboxylase GO:0016831|GO:0045312 KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 A6A12_RS06145 2761191b7bf672fc0da0e6dd28c52c46 377 Gene3D G3DSA:3.20.20.10 15 238 1.4E-36 T 28-03-2018 IPR029066 PLP-binding barrel A6A12_RS10970 8f1415a6c5383b2994839d47a343ac58 416 Gene3D G3DSA:3.40.605.10 238 416 2.4E-31 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A6A12_RS10970 8f1415a6c5383b2994839d47a343ac58 416 PIRSF PIRSF000151 2 416 1.4E-166 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 A6A12_RS10970 8f1415a6c5383b2994839d47a343ac58 416 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 322 343 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A6A12_RS10970 8f1415a6c5383b2994839d47a343ac58 416 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 2 415 39.221 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A6A12_RS10970 8f1415a6c5383b2994839d47a343ac58 416 SUPERFAMILY SSF53720 5 408 7.59E-112 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A6A12_RS10970 8f1415a6c5383b2994839d47a343ac58 416 Pfam PF00171 Aldehyde dehydrogenase family 8 279 8.7E-16 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A6A12_RS10970 8f1415a6c5383b2994839d47a343ac58 416 Gene3D G3DSA:3.40.605.10 2 237 2.6E-42 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A6A12_RS10970 8f1415a6c5383b2994839d47a343ac58 416 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 10 405 5.7E-168 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 A6A12_RS01965 d33deb178cd132afd299a6ad9a0c642e 166 Pfam PF10263 SprT-like family 15 115 2.1E-19 T 28-03-2018 IPR006640 SprT-like A6A12_RS01965 d33deb178cd132afd299a6ad9a0c642e 166 Pfam PF17283 SprT-like zinc ribbon domain 121 161 1.1E-9 T 28-03-2018 IPR035240 SprT-like, zinc ribbon domain A6A12_RS01965 d33deb178cd132afd299a6ad9a0c642e 166 SMART SM00731 12 161 2.6E-52 T 28-03-2018 IPR006640 SprT-like A6A12_RS01965 d33deb178cd132afd299a6ad9a0c642e 166 Hamap MF_00746 Protein SprT [sprT]. 8 161 41.309 T 28-03-2018 IPR023483 Uncharacterised protein family SprT A6A12_RS01965 d33deb178cd132afd299a6ad9a0c642e 166 Gene3D G3DSA:2.60.120.10 6 127 0.0012 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS13605 6ffc242b412f1498e1b6f4443333fe84 189 SUPERFAMILY SSF160930 18 159 3.53E-5 T 28-03-2018 A6A12_RS00725 49677fbbce42affe04e2027fe2a6601c 357 Pfam PF14350 Beta protein 6 346 1.1E-68 T 28-03-2018 IPR025683 Protein beta A6A12_RS05885 96a6bb89984acc7bfa7763035dc7f467 820 Pfam PF00384 Molybdopterin oxidoreductase 87 560 8.2E-80 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A6A12_RS05885 96a6bb89984acc7bfa7763035dc7f467 820 SUPERFAMILY SSF53706 44 660 3.53E-167 T 28-03-2018 A6A12_RS05885 96a6bb89984acc7bfa7763035dc7f467 820 TIGRFAM TIGR02164 torA: trimethylamine-N-oxide reductase TorA 1 819 0.0 T 28-03-2018 IPR011887 Trimethylamine-N-oxide reductase TorA GO:0030151|GO:0042597|GO:0050626 A6A12_RS05885 96a6bb89984acc7bfa7763035dc7f467 820 Pfam PF01568 Molydopterin dinucleotide binding domain 676 796 1.3E-22 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 A6A12_RS05885 96a6bb89984acc7bfa7763035dc7f467 820 Gene3D G3DSA:3.40.228.10 455 517 0.0012 T 28-03-2018 A6A12_RS05885 96a6bb89984acc7bfa7763035dc7f467 820 SUPERFAMILY SSF50692 669 817 5.2E-41 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain A6A12_RS05885 96a6bb89984acc7bfa7763035dc7f467 820 Gene3D G3DSA:2.40.40.20 657 813 1.3E-28 T 28-03-2018 A6A12_RS05885 96a6bb89984acc7bfa7763035dc7f467 820 Gene3D G3DSA:3.40.228.10 182 437 1.2E-52 T 28-03-2018 A6A12_RS05885 96a6bb89984acc7bfa7763035dc7f467 820 Gene3D G3DSA:3.40.228.10 603 656 2.8E-6 T 28-03-2018 A6A12_RS05885 96a6bb89984acc7bfa7763035dc7f467 820 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 503 520 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A6A12_RS05885 96a6bb89984acc7bfa7763035dc7f467 820 Gene3D G3DSA:3.90.55.10 525 602 1.1E-21 T 28-03-2018 A6A12_RS05885 96a6bb89984acc7bfa7763035dc7f467 820 Gene3D G3DSA:3.90.55.10 38 123 1.0E-13 T 28-03-2018 A6A12_RS05885 96a6bb89984acc7bfa7763035dc7f467 820 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 32 3.9E-5 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal A6A12_RS06165 ba88478cab91972ce8f13adef5d577f9 412 SUPERFAMILY SSF53218 2 205 7.72E-32 T 28-03-2018 IPR001453 MoaB/Mog domain A6A12_RS06165 ba88478cab91972ce8f13adef5d577f9 412 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 412 95.912 T 28-03-2018 IPR008135 Competence-induced protein CinA A6A12_RS06165 ba88478cab91972ce8f13adef5d577f9 412 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 398 6.4E-78 T 28-03-2018 IPR008135 Competence-induced protein CinA A6A12_RS06165 ba88478cab91972ce8f13adef5d577f9 412 Gene3D G3DSA:3.40.980.10 1 202 4.6E-33 T 28-03-2018 IPR001453 MoaB/Mog domain A6A12_RS06165 ba88478cab91972ce8f13adef5d577f9 412 PIRSF PIRSF006728 1 392 4.7E-106 T 28-03-2018 IPR008135 Competence-induced protein CinA A6A12_RS06165 ba88478cab91972ce8f13adef5d577f9 412 SMART SM00852 5 172 4.9E-29 T 28-03-2018 IPR001453 MoaB/Mog domain A6A12_RS06165 ba88478cab91972ce8f13adef5d577f9 412 Pfam PF00994 Probable molybdopterin binding domain 5 169 3.2E-28 T 28-03-2018 IPR001453 MoaB/Mog domain A6A12_RS06165 ba88478cab91972ce8f13adef5d577f9 412 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 165 2.8E-25 T 28-03-2018 IPR001453 MoaB/Mog domain A6A12_RS03825 cca3d722b1367342bf54a558cc14041f 946 Gene3D G3DSA:3.40.50.300 131 365 2.3E-28 T 28-03-2018 A6A12_RS03825 cca3d722b1367342bf54a558cc14041f 946 SUPERFAMILY SSF52540 183 221 9.61E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03825 cca3d722b1367342bf54a558cc14041f 946 SUPERFAMILY SSF52540 468 554 9.61E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03825 cca3d722b1367342bf54a558cc14041f 946 Gene3D G3DSA:3.40.50.300 417 593 6.8E-8 T 28-03-2018 A6A12_RS03825 cca3d722b1367342bf54a558cc14041f 946 Pfam PF04851 Type III restriction enzyme, res subunit 160 348 2.8E-36 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A6A12_RS03825 cca3d722b1367342bf54a558cc14041f 946 SUPERFAMILY SSF52540 305 383 5.05E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03825 cca3d722b1367342bf54a558cc14041f 946 SUPERFAMILY SSF52540 138 274 5.05E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03825 cca3d722b1367342bf54a558cc14041f 946 Pfam PF08463 EcoEI R protein C-terminal 747 944 1.8E-60 T 28-03-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 A6A12_RS03825 cca3d722b1367342bf54a558cc14041f 946 SMART SM00487 158 376 1.9E-17 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A6A12_RS07290 f2d99102956a32e9be8df6de36defe7c 565 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 348 527 6.1E-38 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS07290 f2d99102956a32e9be8df6de36defe7c 565 Gene3D G3DSA:1.10.287.950 342 565 6.4E-54 T 28-03-2018 A6A12_RS07290 f2d99102956a32e9be8df6de36defe7c 565 SMART SM00283 302 563 7.7E-71 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS07290 f2d99102956a32e9be8df6de36defe7c 565 SMART SM00304 233 287 3.1E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS07290 f2d99102956a32e9be8df6de36defe7c 565 Gene3D G3DSA:1.10.287.500 253 341 0.001 T 28-03-2018 A6A12_RS07290 f2d99102956a32e9be8df6de36defe7c 565 Gene3D G3DSA:1.20.120.30 46 199 1.5E-10 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain A6A12_RS07290 f2d99102956a32e9be8df6de36defe7c 565 SUPERFAMILY SSF58104 261 564 2.09E-70 T 28-03-2018 A6A12_RS07290 f2d99102956a32e9be8df6de36defe7c 565 Pfam PF12729 Four helix bundle sensory module for signal transduction 27 193 3.6E-19 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain A6A12_RS01240 bbce918a8adc3999bc6961eb56d93329 471 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 36 468 6.7E-82 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A6A12_RS01240 bbce918a8adc3999bc6961eb56d93329 471 Pfam PF00939 Sodium:sulfate symporter transmembrane region 22 467 4.9E-48 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A6A12_RS09535 a54f9da9cf044ab89edbd0c335fbac1a 503 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 33 468 4.9E-122 T 28-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 A6A12_RS09535 a54f9da9cf044ab89edbd0c335fbac1a 503 SUPERFAMILY SSF56801 10 472 4.58E-82 T 28-03-2018 A6A12_RS09535 a54f9da9cf044ab89edbd0c335fbac1a 503 Gene3D G3DSA:3.40.50.980 5 169 7.4E-24 T 28-03-2018 A6A12_RS09535 a54f9da9cf044ab89edbd0c335fbac1a 503 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 28-03-2018 IPR020845 AMP-binding, conserved site A6A12_RS09535 a54f9da9cf044ab89edbd0c335fbac1a 503 Pfam PF00501 AMP-binding enzyme 13 380 1.3E-48 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 A6A12_RS09535 a54f9da9cf044ab89edbd0c335fbac1a 503 Gene3D G3DSA:2.30.38.10 305 373 1.8E-4 T 28-03-2018 A6A12_RS09535 a54f9da9cf044ab89edbd0c335fbac1a 503 Gene3D G3DSA:3.30.300.30 374 476 4.8E-17 T 28-03-2018 A6A12_RS09535 a54f9da9cf044ab89edbd0c335fbac1a 503 Pfam PF13193 AMP-binding enzyme C-terminal domain 389 452 5.1E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain A6A12_RS09535 a54f9da9cf044ab89edbd0c335fbac1a 503 Gene3D G3DSA:3.40.50.980 170 304 1.4E-26 T 28-03-2018 A6A12_RS01300 1e5ef3b01e78ff6a37d1fb9215b1b9e2 88 Gene3D G3DSA:2.30.30.100 4 73 9.2E-34 T 28-03-2018 A6A12_RS01300 1e5ef3b01e78ff6a37d1fb9215b1b9e2 88 SUPERFAMILY SSF50182 7 69 1.62E-24 T 28-03-2018 IPR010920 LSM domain A6A12_RS01300 1e5ef3b01e78ff6a37d1fb9215b1b9e2 88 Pfam PF17209 Hfq protein 7 68 4.3E-31 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A6A12_RS01300 1e5ef3b01e78ff6a37d1fb9215b1b9e2 88 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 3 64 27.727 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A6A12_RS01300 1e5ef3b01e78ff6a37d1fb9215b1b9e2 88 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 7.0E-30 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 A6A12_RS14390 731055e593cd464714a7cb464f051077 293 SMART SM00470 40 130 3.9E-36 T 28-03-2018 IPR003115 ParB/Sulfiredoxin A6A12_RS14390 731055e593cd464714a7cb464f051077 293 SUPERFAMILY SSF110849 42 175 4.92E-33 T 28-03-2018 IPR003115 ParB/Sulfiredoxin A6A12_RS14390 731055e593cd464714a7cb464f051077 293 Gene3D G3DSA:1.10.10.730 131 178 6.2E-18 T 28-03-2018 A6A12_RS14390 731055e593cd464714a7cb464f051077 293 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 38 213 1.8E-56 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 A6A12_RS14390 731055e593cd464714a7cb464f051077 293 Pfam PF02195 ParB-like nuclease domain 42 130 2.2E-28 T 28-03-2018 IPR003115 ParB/Sulfiredoxin A6A12_RS14390 731055e593cd464714a7cb464f051077 293 Gene3D G3DSA:3.90.1530.10 27 130 5.3E-37 T 28-03-2018 A6A12_RS00550 5b2b3f3cd37db24a6b4bc5faa9f652f9 322 PIRSF PIRSF003097 23 318 2.1E-63 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 A6A12_RS02435 45780a826c9f2181a3b072c8267bdefb 285 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 17 280 1.1E-120 T 28-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 A6A12_RS02435 45780a826c9f2181a3b072c8267bdefb 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 282 3.6E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS02435 45780a826c9f2181a3b072c8267bdefb 285 Gene3D G3DSA:1.10.3720.10 16 283 5.1E-42 T 28-03-2018 A6A12_RS02435 45780a826c9f2181a3b072c8267bdefb 285 SUPERFAMILY SSF161098 25 274 1.4E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS02435 45780a826c9f2181a3b072c8267bdefb 285 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 9 275 6.5E-101 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 A6A12_RS09300 3a735408a646e1f6d75d62646dac1694 146 Pfam PF13279 Thioesterase-like superfamily 18 122 3.1E-13 T 28-03-2018 A6A12_RS09300 3a735408a646e1f6d75d62646dac1694 146 Gene3D G3DSA:3.10.129.10 8 142 7.9E-26 T 28-03-2018 A6A12_RS09300 3a735408a646e1f6d75d62646dac1694 146 SUPERFAMILY SSF54637 8 133 3.28E-30 T 28-03-2018 IPR029069 HotDog domain A6A12_RS04930 702c518b0cd38ef034371d5157c99b2f 146 Pfam PF03692 Putative zinc- or iron-chelating domain 23 91 3.9E-8 T 28-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A6A12_RS04930 702c518b0cd38ef034371d5157c99b2f 146 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 1 144 41.334 T 28-03-2018 IPR008228 Uncharacterised conserved protein UCP006173 A6A12_RS04930 702c518b0cd38ef034371d5157c99b2f 146 PIRSF PIRSF006173 1 144 4.7E-65 T 28-03-2018 IPR008228 Uncharacterised conserved protein UCP006173 A6A12_RS11195 f4a68cb9948ee8e6196e07e3eb071ff5 99 Pfam PF07130 YebG protein 1 72 4.6E-31 T 28-03-2018 IPR009813 Uncharacterised protein family YebG A6A12_RS11195 f4a68cb9948ee8e6196e07e3eb071ff5 99 Gene3D G3DSA:1.10.10.710 22 83 5.4E-22 T 28-03-2018 A6A12_RS08265 20dc270a901e0834295556c1e87ae6e3 325 Gene3D G3DSA:1.10.287.110 210 324 5.5E-8 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS08265 20dc270a901e0834295556c1e87ae6e3 325 Pfam PF08238 Sel1 repeat 27 61 1.3E-7 T 28-03-2018 IPR006597 Sel1-like repeat A6A12_RS08265 20dc270a901e0834295556c1e87ae6e3 325 Pfam PF08238 Sel1 repeat 118 131 110.0 T 28-03-2018 IPR006597 Sel1-like repeat A6A12_RS08265 20dc270a901e0834295556c1e87ae6e3 325 Pfam PF08238 Sel1 repeat 64 90 0.004 T 28-03-2018 IPR006597 Sel1-like repeat A6A12_RS08265 20dc270a901e0834295556c1e87ae6e3 325 SMART SM00671 62 97 2.3E-5 T 28-03-2018 IPR006597 Sel1-like repeat A6A12_RS08265 20dc270a901e0834295556c1e87ae6e3 325 SMART SM00671 98 133 61.0 T 28-03-2018 IPR006597 Sel1-like repeat A6A12_RS08265 20dc270a901e0834295556c1e87ae6e3 325 SMART SM00671 26 61 1.1E-7 T 28-03-2018 IPR006597 Sel1-like repeat A6A12_RS08265 20dc270a901e0834295556c1e87ae6e3 325 Gene3D G3DSA:2.60.40.1180 12 188 7.5E-23 T 28-03-2018 A6A12_RS08265 20dc270a901e0834295556c1e87ae6e3 325 SUPERFAMILY SSF46565 271 322 2.22E-11 T 28-03-2018 IPR001623 DnaJ domain A6A12_RS08265 20dc270a901e0834295556c1e87ae6e3 325 SUPERFAMILY SSF81901 21 141 2.35E-22 T 28-03-2018 A6A12_RS01320 866e348e8f154deb02d863e97cece916 62 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 5 59 4.2E-22 T 28-03-2018 IPR019201 Protein of unknown function DUF2065 A6A12_RS11600 04f96d6cec48a07232ee6e844b9600da 160 SUPERFAMILY SSF101738 5 117 1.27E-48 T 28-03-2018 IPR007481 Stringent starvation protein B A6A12_RS11600 04f96d6cec48a07232ee6e844b9600da 160 Pfam PF04386 Stringent starvation protein B 10 160 4.7E-40 T 28-03-2018 IPR007481 Stringent starvation protein B A6A12_RS11600 04f96d6cec48a07232ee6e844b9600da 160 Gene3D G3DSA:2.30.30.220 11 108 6.6E-40 T 28-03-2018 IPR007481 Stringent starvation protein B A6A12_RS11600 04f96d6cec48a07232ee6e844b9600da 160 PIRSF PIRSF005276 4 160 5.1E-61 T 28-03-2018 IPR007481 Stringent starvation protein B A6A12_RS09355 13d95a9ce631ac46b0ae850725715155 202 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 124 137 - T 28-03-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A6A12_RS09355 13d95a9ce631ac46b0ae850725715155 202 Pfam PF01081 KDPG and KHG aldolase 5 197 1.9E-73 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A6A12_RS09355 13d95a9ce631ac46b0ae850725715155 202 SUPERFAMILY SSF51569 3 201 4.21E-65 T 28-03-2018 A6A12_RS09355 13d95a9ce631ac46b0ae850725715155 202 Gene3D G3DSA:3.20.20.70 1 202 3.9E-32 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS09355 13d95a9ce631ac46b0ae850725715155 202 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 5 201 4.0E-82 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A6A12_RS09355 13d95a9ce631ac46b0ae850725715155 202 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 36 45 - T 28-03-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A6A12_RS12510 987e2811ffae0c9aeeddf6e4e23fbe37 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 8.5E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain A6A12_RS12510 987e2811ffae0c9aeeddf6e4e23fbe37 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.898 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12510 987e2811ffae0c9aeeddf6e4e23fbe37 103 SMART SM01403 7 101 8.0E-56 T 28-03-2018 IPR027486 Ribosomal protein S10 domain A6A12_RS12510 987e2811ffae0c9aeeddf6e4e23fbe37 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 3.3E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12510 987e2811ffae0c9aeeddf6e4e23fbe37 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 3.3E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12510 987e2811ffae0c9aeeddf6e4e23fbe37 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 3.3E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12510 987e2811ffae0c9aeeddf6e4e23fbe37 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12510 987e2811ffae0c9aeeddf6e4e23fbe37 103 Gene3D G3DSA:3.30.70.600 3 102 1.2E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain A6A12_RS12510 987e2811ffae0c9aeeddf6e4e23fbe37 103 SUPERFAMILY SSF54999 5 101 1.7E-36 T 28-03-2018 IPR027486 Ribosomal protein S10 domain A6A12_RS12510 987e2811ffae0c9aeeddf6e4e23fbe37 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.1E-45 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS10675 1538b575e8658d4188e3bf8addcf7b9a 141 SUPERFAMILY SSF140566 2 113 4.32E-22 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 A6A12_RS10675 1538b575e8658d4188e3bf8addcf7b9a 141 Gene3D G3DSA:1.20.58.300 1 113 2.0E-13 T 28-03-2018 A6A12_RS10675 1538b575e8658d4188e3bf8addcf7b9a 141 Pfam PF05130 FlgN protein 3 131 3.8E-25 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 A6A12_RS04685 6fd408436680e6ac528810d8f1e7a5c7 64 SMART SM00923 7 57 2.5E-22 T 28-03-2018 IPR005153 MbtH-like protein A6A12_RS04685 6fd408436680e6ac528810d8f1e7a5c7 64 Pfam PF03621 MbtH-like protein 5 56 2.3E-25 T 28-03-2018 IPR005153 MbtH-like protein A6A12_RS04685 6fd408436680e6ac528810d8f1e7a5c7 64 SUPERFAMILY SSF160582 5 63 1.44E-23 T 28-03-2018 A6A12_RS04685 6fd408436680e6ac528810d8f1e7a5c7 64 Gene3D G3DSA:3.90.820.10 6 64 2.3E-26 T 28-03-2018 A6A12_RS07675 df6b55c05eedfb7a102ba8f193896210 120 Pfam PF01042 Endoribonuclease L-PSP 33 114 1.1E-19 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family A6A12_RS07675 df6b55c05eedfb7a102ba8f193896210 120 Gene3D G3DSA:3.30.1330.40 2 120 4.0E-22 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A6A12_RS07675 df6b55c05eedfb7a102ba8f193896210 120 SUPERFAMILY SSF55298 1 115 7.38E-27 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like A6A12_RS03220 a666d5a1425b7b1cc708a5a89c5ab7fc 113 Pfam PF10973 Protein of unknown function (DUF2799) 28 108 8.0E-22 T 28-03-2018 IPR021242 Protein of unknown function DUF2799 A6A12_RS07085 ef5cf4d937c1fe278e090cd43dc15cff 503 SUPERFAMILY SSF53720 3 485 1.03E-147 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A6A12_RS07085 ef5cf4d937c1fe278e090cd43dc15cff 503 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 6 484 2.6E-206 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 A6A12_RS07085 ef5cf4d937c1fe278e090cd43dc15cff 503 Gene3D G3DSA:3.40.309.10 265 462 2.8E-65 T 28-03-2018 A6A12_RS07085 ef5cf4d937c1fe278e090cd43dc15cff 503 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A6A12_RS07085 ef5cf4d937c1fe278e090cd43dc15cff 503 Pfam PF00171 Aldehyde dehydrogenase family 15 480 1.2E-140 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A6A12_RS07085 ef5cf4d937c1fe278e090cd43dc15cff 503 Gene3D G3DSA:3.40.605.10 1 264 1.6E-83 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A6A12_RS08965 79734fa99b0fe3531a919197e8170285 166 SUPERFAMILY SSF116960 1 166 7.32E-64 T 28-03-2018 A6A12_RS08965 79734fa99b0fe3531a919197e8170285 166 Pfam PF03887 YfbU domain 1 166 2.4E-69 T 28-03-2018 IPR005587 Uncharacterised protein family UPF0304, YfbU A6A12_RS08965 79734fa99b0fe3531a919197e8170285 166 Hamap MF_00762 UPF0304 protein YfbU [yfbU]. 1 166 37.442 T 28-03-2018 IPR005587 Uncharacterised protein family UPF0304, YfbU A6A12_RS08965 79734fa99b0fe3531a919197e8170285 166 PIRSF PIRSF006272 1 166 5.3E-78 T 28-03-2018 IPR005587 Uncharacterised protein family UPF0304, YfbU A6A12_RS08965 79734fa99b0fe3531a919197e8170285 166 ProDom PD035118 UPF0304 YFBU PLASMID YPO2563/Y1624/YP2374 YBFU PM1500 OXYGEN ECA3037 VV12093 PROTEIN 1 166 2.0E-79 T 28-03-2018 IPR005587 Uncharacterised protein family UPF0304, YfbU A6A12_RS08965 79734fa99b0fe3531a919197e8170285 166 Gene3D G3DSA:1.10.287.680 2 51 1.0E-24 T 28-03-2018 IPR023145 YfbU, helix-hairpin domain A6A12_RS08965 79734fa99b0fe3531a919197e8170285 166 Gene3D G3DSA:1.10.3190.10 54 166 5.4E-41 T 28-03-2018 IPR023146 YfbU, alpha-helical bundle domain A6A12_RS11875 b3c90e02281a123b54b8db4b4f6c5c68 191 SUPERFAMILY SSF101327 7 178 8.89E-44 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 A6A12_RS11875 b3c90e02281a123b54b8db4b4f6c5c68 191 Pfam PF03695 Uncharacterised protein family (UPF0149) 12 178 7.9E-37 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 A6A12_RS11875 b3c90e02281a123b54b8db4b4f6c5c68 191 Hamap MF_00346 UPF0149 protein YgfB [ygfB]. 5 189 32.884 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 A6A12_RS11875 b3c90e02281a123b54b8db4b4f6c5c68 191 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 12 176 1.6E-10 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 A6A12_RS00425 c9643973ff0067bdaa89854ddb0cacdd 275 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 12 241 2.2E-32 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A6A12_RS00425 c9643973ff0067bdaa89854ddb0cacdd 275 SUPERFAMILY SSF56784 9 274 4.14E-69 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS00425 c9643973ff0067bdaa89854ddb0cacdd 275 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 12 270 5.4E-62 T 28-03-2018 IPR000150 Cof family GO:0016787 A6A12_RS00425 c9643973ff0067bdaa89854ddb0cacdd 275 Gene3D G3DSA:3.40.50.1000 1 275 1.2E-36 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS00425 c9643973ff0067bdaa89854ddb0cacdd 275 ProSitePatterns PS01229 Hypothetical cof family signature 2. 222 244 - T 28-03-2018 A6A12_RS00425 c9643973ff0067bdaa89854ddb0cacdd 275 ProSitePatterns PS01228 Hypothetical cof family signature 1. 12 23 - T 28-03-2018 A6A12_RS00425 c9643973ff0067bdaa89854ddb0cacdd 275 Pfam PF08282 haloacid dehalogenase-like hydrolase 13 270 1.3E-66 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS09330 91655ca53e39480ea4aed80fb2e495ff 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09330 91655ca53e39480ea4aed80fb2e495ff 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09330 91655ca53e39480ea4aed80fb2e495ff 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09330 91655ca53e39480ea4aed80fb2e495ff 241 TIGRFAM TIGR01831 fabG_rel: putative 3-oxoacyl-(acyl-carrier-protein) reductase 5 241 2.0E-125 T 28-03-2018 IPR011285 3-oxoacyl-(acyl-carrier-protein) reductase, putative KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A6A12_RS09330 91655ca53e39480ea4aed80fb2e495ff 241 SUPERFAMILY SSF51735 3 240 3.21E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS09330 91655ca53e39480ea4aed80fb2e495ff 241 Gene3D G3DSA:3.40.50.720 37 241 3.0E-55 T 28-03-2018 A6A12_RS09330 91655ca53e39480ea4aed80fb2e495ff 241 Gene3D G3DSA:3.40.50.720 1 36 1.1E-5 T 28-03-2018 A6A12_RS09330 91655ca53e39480ea4aed80fb2e495ff 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 5.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09330 91655ca53e39480ea4aed80fb2e495ff 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09330 91655ca53e39480ea4aed80fb2e495ff 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 5.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09330 91655ca53e39480ea4aed80fb2e495ff 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 5.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09330 91655ca53e39480ea4aed80fb2e495ff 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 5.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09330 91655ca53e39480ea4aed80fb2e495ff 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.8E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09330 91655ca53e39480ea4aed80fb2e495ff 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 240 1.4E-56 T 28-03-2018 A6A12_RS09330 91655ca53e39480ea4aed80fb2e495ff 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 194 0.0024 T 28-03-2018 A6A12_RS04950 f8af7f5d075b77f1ff2c15c04cba503a 294 SUPERFAMILY SSF74650 6 289 8.79E-74 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 A6A12_RS04950 f8af7f5d075b77f1ff2c15c04cba503a 294 PIRSF PIRSF016020 3 294 3.5E-64 T 28-03-2018 IPR025532 Glucose-6-phosphate 1-epimerase KEGG: 00010+5.1.3.15 A6A12_RS04950 f8af7f5d075b77f1ff2c15c04cba503a 294 Gene3D G3DSA:2.70.98.10 4 292 1.8E-62 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A6A12_RS04950 f8af7f5d075b77f1ff2c15c04cba503a 294 Pfam PF01263 Aldose 1-epimerase 27 289 1.5E-49 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 A6A12_RS04270 f787f299607b1186f650ff7d475a26d3 242 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 60 225 4.1E-58 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 A6A12_RS04270 f787f299607b1186f650ff7d475a26d3 242 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 56 229 5.4E-48 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 A6A12_RS09180 41e4272cc92634d43a1a14d3aca64e64 150 Pfam PF04217 Protein of unknown function, DUF412 8 146 4.4E-57 T 28-03-2018 IPR007334 Uncharacterised protein family UPF0208 A6A12_RS09180 41e4272cc92634d43a1a14d3aca64e64 150 Hamap MF_01101 UPF0208 membrane protein YfbV [yfbV]. 5 150 35.614 T 28-03-2018 IPR007334 Uncharacterised protein family UPF0208 A6A12_RS13530 33006e07faf55adf09c61abbeedf09ac 196 Gene3D G3DSA:1.10.357.10 59 196 9.2E-21 T 28-03-2018 A6A12_RS13530 33006e07faf55adf09c61abbeedf09ac 196 SUPERFAMILY SSF48498 81 191 3.56E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal A6A12_RS13530 33006e07faf55adf09c61abbeedf09ac 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 58 4.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A6A12_RS13530 33006e07faf55adf09c61abbeedf09ac 196 SUPERFAMILY SSF46689 6 78 2.74E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS13530 33006e07faf55adf09c61abbeedf09ac 196 Gene3D G3DSA:1.10.10.60 7 58 1.3E-12 T 28-03-2018 A6A12_RS13530 33006e07faf55adf09c61abbeedf09ac 196 Hamap MF_01839 Nucleoid occlusion factor SlmA [slmA]. 1 196 41.092 T 28-03-2018 IPR023769 Nucleoid occlusion factor SlmA GO:0010974 A6A12_RS10545 ffeb111796e0c27a888912c76203e526 196 SUPERFAMILY SSF53178 5 194 6.8E-70 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A6A12_RS10545 ffeb111796e0c27a888912c76203e526 196 Pfam PF01195 Peptidyl-tRNA hydrolase 7 190 1.2E-53 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A6A12_RS10545 ffeb111796e0c27a888912c76203e526 196 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 18 31 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 A6A12_RS10545 ffeb111796e0c27a888912c76203e526 196 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 5 191 2.4E-69 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A6A12_RS10545 ffeb111796e0c27a888912c76203e526 196 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 112 122 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 A6A12_RS10545 ffeb111796e0c27a888912c76203e526 196 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 5 184 35.965 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A6A12_RS10545 ffeb111796e0c27a888912c76203e526 196 Gene3D G3DSA:3.40.50.1470 1 196 2.7E-69 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 A6A12_RS08255 929cb2123804621a9fcad660f0fc45cb 229 Gene3D G3DSA:3.40.1550.10 4 174 6.4E-28 T 28-03-2018 IPR028976 CheC-like domain A6A12_RS08255 929cb2123804621a9fcad660f0fc45cb 229 SUPERFAMILY SSF103039 10 173 5.36E-25 T 28-03-2018 IPR028976 CheC-like domain A6A12_RS08255 929cb2123804621a9fcad660f0fc45cb 229 Pfam PF11813 Protein of unknown function (DUF3334) 3 229 2.7E-116 T 28-03-2018 IPR024513 Protein of unknown function DUF3334 A6A12_RS12280 a33ce0a49483ee1da94c8d9918c124eb 419 Pfam PF02687 FtsX-like permease family 317 410 2.6E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A6A12_RS12280 a33ce0a49483ee1da94c8d9918c124eb 419 Pfam PF12704 MacB-like periplasmic core domain 20 207 8.2E-10 T 28-03-2018 IPR025857 MacB-like periplasmic core domain A6A12_RS04495 f1167fe580700e73a9f622adf9275425 284 Gene3D G3DSA:1.25.40.10 119 196 2.3E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS04495 f1167fe580700e73a9f622adf9275425 284 Pfam PF14559 Tetratricopeptide repeat 124 190 2.7E-11 T 28-03-2018 A6A12_RS04495 f1167fe580700e73a9f622adf9275425 284 Pfam PF00085 Thioredoxin 7 109 1.4E-13 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 A6A12_RS04495 f1167fe580700e73a9f622adf9275425 284 SUPERFAMILY SSF48452 111 246 4.91E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS04495 f1167fe580700e73a9f622adf9275425 284 SUPERFAMILY SSF52833 3 112 1.75E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS04495 f1167fe580700e73a9f622adf9275425 284 Gene3D G3DSA:1.25.40.10 197 284 9.0E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS04495 f1167fe580700e73a9f622adf9275425 284 Pfam PF14561 Tetratricopeptide repeat 195 284 1.7E-24 T 28-03-2018 A6A12_RS04495 f1167fe580700e73a9f622adf9275425 284 Gene3D G3DSA:3.40.30.10 5 118 9.0E-21 T 28-03-2018 A6A12_RS10630 156f43e07759cb330622270270a5a2ed 249 Pfam PF00460 Flagella basal body rod protein 8 35 2.1E-5 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 A6A12_RS10630 156f43e07759cb330622270270a5a2ed 249 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 6 226 3.0E-53 T 28-03-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 A6A12_RS10630 156f43e07759cb330622270270a5a2ed 249 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 172 242 8.1E-24 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain A6A12_RS10630 156f43e07759cb330622270270a5a2ed 249 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 121 1.8E-32 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G A6A12_RS10630 156f43e07759cb330622270270a5a2ed 249 SUPERFAMILY SSF117143 77 207 9.15E-18 T 28-03-2018 A6A12_RS04415 3d4c87512dabb82cf978aec052875e6f 366 Gene3D G3DSA:3.40.50.300 116 343 9.2E-27 T 28-03-2018 A6A12_RS04415 3d4c87512dabb82cf978aec052875e6f 366 Pfam PF02562 PhoH-like protein 120 323 2.1E-93 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 A6A12_RS04415 3d4c87512dabb82cf978aec052875e6f 366 SUPERFAMILY SSF52540 119 320 7.94E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS04415 3d4c87512dabb82cf978aec052875e6f 366 Gene3D G3DSA:3.30.1370.10 2 70 0.0019 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 A6A12_RS04415 3d4c87512dabb82cf978aec052875e6f 366 SUPERFAMILY SSF54791 17 77 5.77E-5 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 A6A12_RS14330 758d541d9a7bb542cba184b8a95de9a2 301 Gene3D G3DSA:1.10.10.10 2 84 7.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS14330 758d541d9a7bb542cba184b8a95de9a2 301 Gene3D G3DSA:3.40.190.10 89 179 5.8E-8 T 28-03-2018 A6A12_RS14330 758d541d9a7bb542cba184b8a95de9a2 301 SUPERFAMILY SSF53850 88 287 1.41E-22 T 28-03-2018 A6A12_RS14330 758d541d9a7bb542cba184b8a95de9a2 301 Pfam PF03466 LysR substrate binding domain 89 288 2.8E-19 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS14330 758d541d9a7bb542cba184b8a95de9a2 301 Gene3D G3DSA:3.40.190.10 180 283 6.8E-6 T 28-03-2018 A6A12_RS14330 758d541d9a7bb542cba184b8a95de9a2 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 1.5E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS14330 758d541d9a7bb542cba184b8a95de9a2 301 SUPERFAMILY SSF46785 5 86 2.94E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS14105 ea5e711b39c79e8b995a3dc032f6af4c 514 Pfam PF02646 RmuC family 181 477 1.5E-103 T 28-03-2018 IPR003798 DNA recombination RmuC A6A12_RS14105 ea5e711b39c79e8b995a3dc032f6af4c 514 Gene3D G3DSA:1.20.5.340 192 343 3.4E-21 T 28-03-2018 A6A12_RS03200 7fa78717aefe9c9337c1c73ced299287 169 Pfam PF01252 Signal peptidase (SPase) II 19 161 3.5E-38 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A6A12_RS03200 7fa78717aefe9c9337c1c73ced299287 169 ProSitePatterns PS00855 Signal peptidases II signature. 109 121 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A6A12_RS03200 7fa78717aefe9c9337c1c73ced299287 169 TIGRFAM TIGR00077 lspA: signal peptidase II 10 164 1.0E-47 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A6A12_RS03200 7fa78717aefe9c9337c1c73ced299287 169 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 10 167 16.9 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A6A12_RS03200 7fa78717aefe9c9337c1c73ced299287 169 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 142 158 2.0E-18 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A6A12_RS03200 7fa78717aefe9c9337c1c73ced299287 169 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 106 121 2.0E-18 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A6A12_RS03200 7fa78717aefe9c9337c1c73ced299287 169 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 58 66 2.0E-18 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 A6A12_RS08235 d20140fb2cbd43245b8a0d4fd5809f72 510 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 3 504 44.012 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A6A12_RS08235 d20140fb2cbd43245b8a0d4fd5809f72 510 Gene3D G3DSA:1.20.200.10 199 506 1.1E-120 T 28-03-2018 A6A12_RS08235 d20140fb2cbd43245b8a0d4fd5809f72 510 Gene3D G3DSA:1.10.275.10 2 197 1.1E-72 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal A6A12_RS08235 d20140fb2cbd43245b8a0d4fd5809f72 510 Pfam PF00221 Aromatic amino acid lyase 11 470 9.2E-186 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 A6A12_RS08235 d20140fb2cbd43245b8a0d4fd5809f72 510 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 A6A12_RS08235 d20140fb2cbd43245b8a0d4fd5809f72 510 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 5 505 3.4E-213 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 A6A12_RS08235 d20140fb2cbd43245b8a0d4fd5809f72 510 SUPERFAMILY SSF48557 4 507 7.69E-192 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 A6A12_RS04055 66fbaf7c3cd92630d596050dec9cf55b 294 Gene3D G3DSA:1.10.600.10 2 294 1.3E-82 T 28-03-2018 IPR008949 Isoprenoid synthase domain A6A12_RS04055 66fbaf7c3cd92630d596050dec9cf55b 294 SUPERFAMILY SSF48576 4 288 1.06E-84 T 28-03-2018 IPR008949 Isoprenoid synthase domain A6A12_RS04055 66fbaf7c3cd92630d596050dec9cf55b 294 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 213 225 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site A6A12_RS04055 66fbaf7c3cd92630d596050dec9cf55b 294 Pfam PF00348 Polyprenyl synthetase 30 270 3.0E-57 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 A6A12_RS04055 66fbaf7c3cd92630d596050dec9cf55b 294 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 79 95 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site A6A12_RS07580 722f941e8d037e79e799e8c7d4e2db8c 243 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 27 241 4.2E-30 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS07580 722f941e8d037e79e799e8c7d4e2db8c 243 Gene3D G3DSA:3.40.190.10 20 162 6.5E-21 T 28-03-2018 A6A12_RS07580 722f941e8d037e79e799e8c7d4e2db8c 243 Gene3D G3DSA:3.40.190.10 163 243 8.8E-6 T 28-03-2018 A6A12_RS07580 722f941e8d037e79e799e8c7d4e2db8c 243 SUPERFAMILY SSF53850 24 241 4.77E-41 T 28-03-2018 A6A12_RS07580 722f941e8d037e79e799e8c7d4e2db8c 243 SMART SM00062 22 242 5.4E-8 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF A6A12_RS10600 be056a961c33a2c636e6696a319a78ec 397 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 142 6.7E-11 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A6A12_RS10600 be056a961c33a2c636e6696a319a78ec 397 Gene3D G3DSA:1.20.1330.10 40 372 1.3E-20 T 28-03-2018 A6A12_RS10600 be056a961c33a2c636e6696a319a78ec 397 Pfam PF00700 Bacterial flagellin C-terminal helical region 320 397 1.6E-5 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 A6A12_RS10600 be056a961c33a2c636e6696a319a78ec 397 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 4 397 9.7E-97 T 28-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 A6A12_RS10600 be056a961c33a2c636e6696a319a78ec 397 SUPERFAMILY SSF64518 1 397 1.05E-66 T 28-03-2018 A6A12_RS07215 dc4a8c2bfb3c055f49e8144583ed6511 400 Gene3D G3DSA:1.20.1090.10 204 382 2.0E-56 T 28-03-2018 A6A12_RS07215 dc4a8c2bfb3c055f49e8144583ed6511 400 SUPERFAMILY SSF56796 29 399 8.24E-112 T 28-03-2018 A6A12_RS07215 dc4a8c2bfb3c055f49e8144583ed6511 400 Pfam PF00465 Iron-containing alcohol dehydrogenase 30 388 9.5E-112 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A6A12_RS07215 dc4a8c2bfb3c055f49e8144583ed6511 400 Gene3D G3DSA:3.40.50.1970 29 202 2.0E-44 T 28-03-2018 A6A12_RS07095 9137a1b5215ab4b0f78afbad8cca9916 296 SUPERFAMILY SSF51658 5 288 1.8E-57 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A6A12_RS07095 9137a1b5215ab4b0f78afbad8cca9916 296 TIGRFAM TIGR04379 myo_inos_iolE: myo-inosose-2 dehydratase 3 289 1.6E-129 T 28-03-2018 IPR030823 IolE/MocC family KEGG: 00562+4.2.1.44 A6A12_RS07095 9137a1b5215ab4b0f78afbad8cca9916 296 Pfam PF01261 Xylose isomerase-like TIM barrel 32 243 3.3E-28 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A6A12_RS07095 9137a1b5215ab4b0f78afbad8cca9916 296 Gene3D G3DSA:3.20.20.150 1 293 9.7E-53 T 28-03-2018 A6A12_RS10525 88366e6a5d495c04324d69102329f342 419 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 154 9.8E-53 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A6A12_RS10525 88366e6a5d495c04324d69102329f342 419 Gene3D G3DSA:3.40.50.720 159 311 3.4E-21 T 28-03-2018 A6A12_RS10525 88366e6a5d495c04324d69102329f342 419 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 97 120 - T 28-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A6A12_RS10525 88366e6a5d495c04324d69102329f342 419 PIRSF PIRSF000445 1 419 1.2E-156 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A6A12_RS10525 88366e6a5d495c04324d69102329f342 419 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 318 412 1.1E-21 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A6A12_RS10525 88366e6a5d495c04324d69102329f342 419 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 415 3.9E-146 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A6A12_RS10525 88366e6a5d495c04324d69102329f342 419 SUPERFAMILY SSF69075 315 416 7.06E-27 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A6A12_RS10525 88366e6a5d495c04324d69102329f342 419 Gene3D G3DSA:1.10.1200.70 330 416 3.3E-21 T 28-03-2018 A6A12_RS10525 88366e6a5d495c04324d69102329f342 419 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 170 304 2.5E-49 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase A6A12_RS10525 88366e6a5d495c04324d69102329f342 419 SUPERFAMILY SSF69742 1 156 1.44E-49 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A6A12_RS10525 88366e6a5d495c04324d69102329f342 419 SUPERFAMILY SSF51735 161 313 7.56E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS10525 88366e6a5d495c04324d69102329f342 419 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 416 30.835 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 A6A12_RS07450 32cdd3080741eb5e712f88e667c2c62e 629 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 479 622 9.4E-48 T 28-03-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding A6A12_RS07450 32cdd3080741eb5e712f88e667c2c62e 629 Pfam PF03445 Putative nucleotidyltransferase DUF294 305 442 7.3E-47 T 28-03-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 A6A12_RS07450 32cdd3080741eb5e712f88e667c2c62e 629 Gene3D G3DSA:2.60.120.10 2 140 3.3E-27 T 28-03-2018 IPR014710 RmlC-like jelly roll fold A6A12_RS07450 32cdd3080741eb5e712f88e667c2c62e 629 Gene3D G3DSA:3.10.580.10 141 285 6.9E-23 T 28-03-2018 A6A12_RS07450 32cdd3080741eb5e712f88e667c2c62e 629 SUPERFAMILY SSF51206 7 129 1.96E-28 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like A6A12_RS07450 32cdd3080741eb5e712f88e667c2c62e 629 SUPERFAMILY SSF54631 145 279 3.94E-26 T 28-03-2018 A6A12_RS07450 32cdd3080741eb5e712f88e667c2c62e 629 Pfam PF00027 Cyclic nucleotide-binding domain 37 119 4.0E-15 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A6A12_RS07450 32cdd3080741eb5e712f88e667c2c62e 629 Pfam PF00571 CBS domain 152 214 2.8E-6 T 28-03-2018 IPR000644 CBS domain A6A12_RS07450 32cdd3080741eb5e712f88e667c2c62e 629 Pfam PF00571 CBS domain 226 278 7.1E-11 T 28-03-2018 IPR000644 CBS domain A6A12_RS07450 32cdd3080741eb5e712f88e667c2c62e 629 SMART SM00100 17 134 8.7E-8 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain A6A12_RS07450 32cdd3080741eb5e712f88e667c2c62e 629 SMART SM00116 233 280 2.4E-7 T 28-03-2018 IPR000644 CBS domain A6A12_RS07450 32cdd3080741eb5e712f88e667c2c62e 629 SMART SM00116 159 216 0.6 T 28-03-2018 IPR000644 CBS domain A6A12_RS08150 f5000b1912d7915d403a9a0692dfb908 325 SUPERFAMILY SSF56935 35 325 2.32E-11 T 28-03-2018 A6A12_RS08150 f5000b1912d7915d403a9a0692dfb908 325 Gene3D G3DSA:2.40.160.10 15 325 1.7E-10 T 28-03-2018 A6A12_RS08150 f5000b1912d7915d403a9a0692dfb908 325 Pfam PF16966 Porin-like glycoporin RafY 48 325 1.7E-57 T 28-03-2018 IPR016963 Glycoporin RafY A6A12_RS03660 6663f61f5e548d3fdffff0e1eda2f6d4 387 Gene3D G3DSA:3.20.20.140 71 315 5.2E-39 T 28-03-2018 A6A12_RS03660 6663f61f5e548d3fdffff0e1eda2f6d4 387 Pfam PF01979 Amidohydrolase family 86 374 1.8E-5 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 A6A12_RS03660 6663f61f5e548d3fdffff0e1eda2f6d4 387 PIRSF PIRSF039004 6 386 1.1E-127 T 28-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative A6A12_RS03660 6663f61f5e548d3fdffff0e1eda2f6d4 387 SUPERFAMILY SSF51338 10 61 9.94E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A6A12_RS03660 6663f61f5e548d3fdffff0e1eda2f6d4 387 SUPERFAMILY SSF51338 327 374 9.94E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A6A12_RS03660 6663f61f5e548d3fdffff0e1eda2f6d4 387 SUPERFAMILY SSF51556 61 326 9.21E-65 T 28-03-2018 IPR032466 Metal-dependent hydrolase A6A12_RS03660 6663f61f5e548d3fdffff0e1eda2f6d4 387 TIGRFAM TIGR03583 EF_0837: putative amidohydrolase, EF_0837/AHA_3915 family 11 374 1.1E-157 T 28-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative A6A12_RS03660 6663f61f5e548d3fdffff0e1eda2f6d4 387 Gene3D G3DSA:2.30.40.10 6 70 9.0E-6 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A6A12_RS03660 6663f61f5e548d3fdffff0e1eda2f6d4 387 Gene3D G3DSA:2.30.40.10 316 383 0.0042 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 A6A12_RS06775 9a792b8bfe0bd6a635fd1a908ef9381c 256 Gene3D G3DSA:1.10.3720.10 5 256 4.1E-39 T 28-03-2018 A6A12_RS06775 9a792b8bfe0bd6a635fd1a908ef9381c 256 SUPERFAMILY SSF161098 5 254 4.39E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS06775 9a792b8bfe0bd6a635fd1a908ef9381c 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 249 2.8E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS04005 2905edbe3a872cccbd06ba5f1c125052 84 PRINTS PR01249 Ribosomal protein L31 signature 45 60 1.5E-15 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS04005 2905edbe3a872cccbd06ba5f1c125052 84 PRINTS PR01249 Ribosomal protein L31 signature 60 78 1.5E-15 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS04005 2905edbe3a872cccbd06ba5f1c125052 84 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.5E-15 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS04005 2905edbe3a872cccbd06ba5f1c125052 84 Pfam PF01197 Ribosomal protein L31 1 79 2.9E-26 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS04005 2905edbe3a872cccbd06ba5f1c125052 84 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 27.558 T 28-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS04005 2905edbe3a872cccbd06ba5f1c125052 84 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 3.4E-18 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS04005 2905edbe3a872cccbd06ba5f1c125052 84 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS04005 2905edbe3a872cccbd06ba5f1c125052 84 SUPERFAMILY SSF143800 1 81 2.71E-22 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS06360 719fb1c10826c1997077735f5103ad88 364 Gene3D G3DSA:3.20.20.70 4 364 7.6E-127 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS06360 719fb1c10826c1997077735f5103ad88 364 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 340 7.7E-99 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 A6A12_RS06360 719fb1c10826c1997077735f5103ad88 364 SUPERFAMILY SSF51395 2 363 3.36E-127 T 28-03-2018 A6A12_RS08045 8b1822dd8e6d7e735d5745bf301c2219 153 PRINTS PR01489 Gram-negative bacterial RTX toxin-activating protein C signature 85 107 2.0E-5 T 28-03-2018 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 A6A12_RS08045 8b1822dd8e6d7e735d5745bf301c2219 153 PRINTS PR01489 Gram-negative bacterial RTX toxin-activating protein C signature 63 81 2.0E-5 T 28-03-2018 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 A6A12_RS08045 8b1822dd8e6d7e735d5745bf301c2219 153 PRINTS PR01489 Gram-negative bacterial RTX toxin-activating protein C signature 20 36 2.0E-5 T 28-03-2018 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 A6A12_RS08045 8b1822dd8e6d7e735d5745bf301c2219 153 Pfam PF02794 RTX toxin acyltransferase family 18 150 1.9E-45 T 28-03-2018 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 A6A12_RS04035 5d89498d0d0893694ccb6f8a18fb596c 347 Pfam PF12069 Protein of unknown function (DUF3549) 3 341 6.9E-136 T 28-03-2018 IPR021936 Protein of unknown function DUF3549 A6A12_RS10135 9027b3551355672cba2531feecacfb98 207 Pfam PF03458 UPF0126 domain 92 163 5.0E-19 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 A6A12_RS10135 9027b3551355672cba2531feecacfb98 207 Pfam PF03458 UPF0126 domain 5 76 4.3E-19 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 A6A12_RS04340 ac98355efaea23f1624f6118f0b867a3 217 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 74 127 2.0E-21 T 28-03-2018 A6A12_RS04340 ac98355efaea23f1624f6118f0b867a3 217 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 25 202 3.1E-71 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A6A12_RS04340 ac98355efaea23f1624f6118f0b867a3 217 Hamap MF_00013 Octanoyltransferase [lipB]. 4 205 38.086 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A6A12_RS04340 ac98355efaea23f1624f6118f0b867a3 217 Pfam PF03099 Biotin/lipoate A/B protein ligase family 58 158 1.2E-8 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 A6A12_RS04340 ac98355efaea23f1624f6118f0b867a3 217 Gene3D G3DSA:3.30.930.10 1 203 1.6E-63 T 28-03-2018 A6A12_RS04340 ac98355efaea23f1624f6118f0b867a3 217 PIRSF PIRSF016262 1 216 5.2E-61 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 A6A12_RS04340 ac98355efaea23f1624f6118f0b867a3 217 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 70 85 - T 28-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A6A12_RS04340 ac98355efaea23f1624f6118f0b867a3 217 SUPERFAMILY SSF55681 3 203 1.74E-68 T 28-03-2018 A6A12_RS13485 ce18667ad1acb022e7dd49c754b56057 261 Gene3D G3DSA:3.90.550.10 3 223 2.0E-20 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13485 ce18667ad1acb022e7dd49c754b56057 261 SUPERFAMILY SSF53448 4 144 1.19E-23 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13485 ce18667ad1acb022e7dd49c754b56057 261 Pfam PF00535 Glycosyl transferase family 2 10 127 1.0E-14 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A6A12_RS05750 283c4467ce9aced40978abd146395fba 226 Pfam PF09335 SNARE associated Golgi protein 65 181 2.4E-21 T 28-03-2018 IPR032816 SNARE associated Golgi protein A6A12_RS01115 eeb8867eeee5ff6e143bc4c8f0e68c0c 348 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 210 331 2.9E-31 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS01115 eeb8867eeee5ff6e143bc4c8f0e68c0c 348 SUPERFAMILY SSF56176 8 201 1.24E-39 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 A6A12_RS01115 eeb8867eeee5ff6e143bc4c8f0e68c0c 348 Gene3D G3DSA:3.30.43.10 1 71 1.1E-17 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 A6A12_RS01115 eeb8867eeee5ff6e143bc4c8f0e68c0c 348 Gene3D G3DSA:3.90.78.10 225 337 8.0E-36 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS01115 eeb8867eeee5ff6e143bc4c8f0e68c0c 348 Gene3D G3DSA:3.30.465.10 73 222 7.7E-43 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 A6A12_RS01115 eeb8867eeee5ff6e143bc4c8f0e68c0c 348 Pfam PF01565 FAD binding domain 24 142 1.3E-19 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 A6A12_RS01115 eeb8867eeee5ff6e143bc4c8f0e68c0c 348 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 348 79.955 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS01115 eeb8867eeee5ff6e143bc4c8f0e68c0c 348 SUPERFAMILY SSF56194 207 341 6.28E-46 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS01115 eeb8867eeee5ff6e143bc4c8f0e68c0c 348 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 332 1.6E-91 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A6A12_RS13745 efa0a9346e4719be31d0a7df74e1e6e5 282 Gene3D G3DSA:1.10.10.10 1 97 1.4E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS13745 efa0a9346e4719be31d0a7df74e1e6e5 282 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 75 2.4E-23 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A6A12_RS13745 efa0a9346e4719be31d0a7df74e1e6e5 282 SUPERFAMILY SSF53697 99 276 3.93E-37 T 28-03-2018 A6A12_RS13745 efa0a9346e4719be31d0a7df74e1e6e5 282 Pfam PF01380 SIS domain 132 257 1.2E-17 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A6A12_RS13745 efa0a9346e4719be31d0a7df74e1e6e5 282 SUPERFAMILY SSF46689 1 77 2.87E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS13745 efa0a9346e4719be31d0a7df74e1e6e5 282 Gene3D G3DSA:3.40.50.10490 98 282 3.5E-34 T 28-03-2018 A6A12_RS14195 a8006eede1a0d284dba664b32780a00a 259 Gene3D G3DSA:3.40.50.150 57 258 6.8E-36 T 28-03-2018 A6A12_RS14195 a8006eede1a0d284dba664b32780a00a 259 Pfam PF04445 Putative SAM-dependent methyltransferase 19 255 2.6E-105 T 28-03-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 A6A12_RS14195 a8006eede1a0d284dba664b32780a00a 259 Gene3D G3DSA:3.40.1630.10 3 56 1.2E-23 T 28-03-2018 A6A12_RS14195 a8006eede1a0d284dba664b32780a00a 259 SUPERFAMILY SSF53335 7 255 3.45E-72 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS14195 a8006eede1a0d284dba664b32780a00a 259 Hamap MF_01523 Ribosomal RNA small subunit methyltransferase J [rsmJ]. 3 256 38.836 T 28-03-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 A6A12_RS10200 6b21144b0e74dd4b6ed91f00386cd28d 150 PIRSF PIRSF019404 1 146 5.7E-29 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 A6A12_RS10200 6b21144b0e74dd4b6ed91f00386cd28d 150 Pfam PF02050 Flagellar FliJ protein 17 140 1.2E-30 T 28-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 A6A12_RS10200 6b21144b0e74dd4b6ed91f00386cd28d 150 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 3 142 3.7E-36 T 28-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 A6A12_RS09550 85fa561e268e977ef2f005de48a23ae7 261 SUPERFAMILY SSF53474 7 260 1.09E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS09550 85fa561e268e977ef2f005de48a23ae7 261 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 17 258 6.5E-82 T 28-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 A6A12_RS09550 85fa561e268e977ef2f005de48a23ae7 261 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 14 259 34.766 T 28-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 A6A12_RS09550 85fa561e268e977ef2f005de48a23ae7 261 Gene3D G3DSA:3.40.50.1820 5 260 2.2E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS09550 85fa561e268e977ef2f005de48a23ae7 261 Pfam PF12697 Alpha/beta hydrolase family 20 252 3.1E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A6A12_RS07350 184f2e6d206b6e8411c6c52f90c94bc0 209 Gene3D G3DSA:3.90.79.10 13 207 1.5E-37 T 28-03-2018 A6A12_RS07350 184f2e6d206b6e8411c6c52f90c94bc0 209 Pfam PF00293 NUDIX domain 50 160 2.5E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A6A12_RS07350 184f2e6d206b6e8411c6c52f90c94bc0 209 SUPERFAMILY SSF55811 40 199 1.49E-32 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A6A12_RS11560 2ba37b761ad1d8cc176dc1a27f219c74 105 Pfam PF04999 Cell division protein FtsL 8 103 1.1E-36 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 A6A12_RS11560 2ba37b761ad1d8cc176dc1a27f219c74 105 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 20 102 2.3E-27 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 A6A12_RS11560 2ba37b761ad1d8cc176dc1a27f219c74 105 Hamap MF_00910 Cell division protein FtsL [ftsL]. 19 102 16.544 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 A6A12_RS12205 9bfc23033c8c6e13dbac826a60ef7a99 531 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 64 253 3.9E-8 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS12205 9bfc23033c8c6e13dbac826a60ef7a99 531 SUPERFAMILY SSF161098 18 256 6.41E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS12205 9bfc23033c8c6e13dbac826a60ef7a99 531 TIGRFAM TIGR01253 thiP: thiamine/thiamine pyrophosphate ABC transporter, permease protein 8 518 6.1E-165 T 28-03-2018 IPR005947 Thiamine ABC transporter, permease protein GO:0005215|GO:0015888|GO:0016021 A6A12_RS12205 9bfc23033c8c6e13dbac826a60ef7a99 531 Gene3D G3DSA:1.10.3720.10 40 259 2.4E-25 T 28-03-2018 A6A12_RS12205 9bfc23033c8c6e13dbac826a60ef7a99 531 Gene3D G3DSA:1.10.3720.10 315 526 2.4E-24 T 28-03-2018 A6A12_RS12205 9bfc23033c8c6e13dbac826a60ef7a99 531 SUPERFAMILY SSF161098 283 522 4.67E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS10410 5b6c8731f9e53be312156641ad687f77 472 Pfam PF13245 AAA domain 6 163 2.3E-12 T 28-03-2018 A6A12_RS10410 5b6c8731f9e53be312156641ad687f77 472 SUPERFAMILY SSF52540 285 468 3.78E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS10410 5b6c8731f9e53be312156641ad687f77 472 SUPERFAMILY SSF52540 11 219 3.78E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS10410 5b6c8731f9e53be312156641ad687f77 472 Gene3D G3DSA:3.40.50.300 3 183 1.8E-20 T 28-03-2018 A6A12_RS06050 970f104652423c054ad324c3bea3dd80 118 Gene3D G3DSA:2.40.10.220 2 109 8.1E-8 T 28-03-2018 A6A12_RS06050 970f104652423c054ad324c3bea3dd80 118 Pfam PF07238 PilZ domain 8 88 3.3E-6 T 28-03-2018 IPR009875 PilZ domain GO:0035438 A6A12_RS00680 c7715afa07dc22911de13aeea18c271a 834 SUPERFAMILY SSF69369 548 703 7.59E-9 T 28-03-2018 IPR016128 Pyosin/cloacin translocation domain GO:0009405 A6A12_RS00680 c7715afa07dc22911de13aeea18c271a 834 Pfam PF06958 S-type Pyocin 568 698 2.0E-26 T 28-03-2018 IPR016128 Pyosin/cloacin translocation domain GO:0009405 A6A12_RS00680 c7715afa07dc22911de13aeea18c271a 834 Gene3D G3DSA:3.10.350.10 360 447 6.8E-7 T 28-03-2018 A6A12_RS00310 2751dd6f56f384ea1c9f66efc7022c89 276 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 5 273 31.426 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A6A12_RS00310 2751dd6f56f384ea1c9f66efc7022c89 276 SUPERFAMILY SSF51735 106 273 1.42E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS00310 2751dd6f56f384ea1c9f66efc7022c89 276 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 120 195 5.0E-13 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase A6A12_RS00310 2751dd6f56f384ea1c9f66efc7022c89 276 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 7 274 8.9E-88 T 28-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A6A12_RS00310 2751dd6f56f384ea1c9f66efc7022c89 276 SUPERFAMILY SSF53223 6 105 2.07E-32 T 28-03-2018 A6A12_RS00310 2751dd6f56f384ea1c9f66efc7022c89 276 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 10 92 2.9E-25 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 A6A12_RS00310 2751dd6f56f384ea1c9f66efc7022c89 276 Gene3D G3DSA:3.40.50.10860 1 115 6.5E-37 T 28-03-2018 A6A12_RS00310 2751dd6f56f384ea1c9f66efc7022c89 276 Gene3D G3DSA:3.40.50.720 116 276 1.4E-28 T 28-03-2018 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 PRINTS PR00477 Phosphoglycerate kinase family signature 303 328 4.4E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 PRINTS PR00477 Phosphoglycerate kinase family signature 186 205 4.4E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 4.4E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 4.4E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 PRINTS PR00477 Phosphoglycerate kinase family signature 336 347 4.4E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 PRINTS PR00477 Phosphoglycerate kinase family signature 359 376 4.4E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 4.4E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 PRINTS PR00477 Phosphoglycerate kinase family signature 163 185 4.4E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 PRINTS PR00477 Phosphoglycerate kinase family signature 104 119 4.4E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 SUPERFAMILY SSF53748 3 382 3.65E-143 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 28-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 PIRSF PIRSF000724 1 387 5.5E-133 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 383 38.155 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 Gene3D G3DSA:3.40.50.1260 3 174 5.6E-60 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 Gene3D G3DSA:3.40.50.1260 175 371 1.2E-74 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS01995 a5c9703be68d50b63f2a2d5c23b13b42 387 Pfam PF00162 Phosphoglycerate kinase 6 373 9.9E-138 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A6A12_RS03610 a6a1151cfb66322cf578c80628be5a22 202 ProSitePatterns PS01114 GPR1/FUN34/yaaH family signature. 7 16 - T 28-03-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 A6A12_RS03610 a6a1151cfb66322cf578c80628be5a22 202 Pfam PF01184 GPR1/FUN34/yaaH family 3 180 2.4E-35 T 28-03-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 A6A12_RS10940 d31324622c6d7ef58b301b3fcf94983f 155 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 10 150 1.8E-41 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 A6A12_RS10940 d31324622c6d7ef58b301b3fcf94983f 155 SUPERFAMILY SSF48013 7 153 1.18E-38 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A6A12_RS10940 d31324622c6d7ef58b301b3fcf94983f 155 Pfam PF01029 NusB family 11 149 3.4E-35 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A6A12_RS10940 d31324622c6d7ef58b301b3fcf94983f 155 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 8 153 22.647 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 A6A12_RS10940 d31324622c6d7ef58b301b3fcf94983f 155 Gene3D G3DSA:1.10.940.10 5 155 3.3E-40 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A6A12_RS02860 8e841e6e346365650a9f54f8bf6a20b6 361 Pfam PF01594 AI-2E family transporter 14 347 1.4E-51 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like A6A12_RS01785 62fbfbdde9a4fd67aa15f418bcbe8f8a 160 PIRSF PIRSF000194 1 160 6.3E-64 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A6A12_RS01785 62fbfbdde9a4fd67aa15f418bcbe8f8a 160 Pfam PF00186 Dihydrofolate reductase 3 158 8.9E-62 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A6A12_RS01785 62fbfbdde9a4fd67aa15f418bcbe8f8a 160 PRINTS PR00070 Dihydrofolate reductase signature 41 52 8.5E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A6A12_RS01785 62fbfbdde9a4fd67aa15f418bcbe8f8a 160 PRINTS PR00070 Dihydrofolate reductase signature 14 24 8.5E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A6A12_RS01785 62fbfbdde9a4fd67aa15f418bcbe8f8a 160 PRINTS PR00070 Dihydrofolate reductase signature 28 36 8.5E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A6A12_RS01785 62fbfbdde9a4fd67aa15f418bcbe8f8a 160 PRINTS PR00070 Dihydrofolate reductase signature 92 106 8.5E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 A6A12_RS01785 62fbfbdde9a4fd67aa15f418bcbe8f8a 160 SUPERFAMILY SSF53597 1 159 1.96E-58 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A6A12_RS01785 62fbfbdde9a4fd67aa15f418bcbe8f8a 160 Gene3D G3DSA:3.40.430.10 1 160 7.8E-54 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 A6A12_RS02095 d2d9724b1d2f7f77f6ef157b4871bc7e 98 SUPERFAMILY SSF54909 1 97 1.13E-27 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel A6A12_RS02095 d2d9724b1d2f7f77f6ef157b4871bc7e 98 SMART SM00886 2 98 3.6E-33 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel A6A12_RS02095 d2d9724b1d2f7f77f6ef157b4871bc7e 98 Gene3D G3DSA:3.30.70.100 1 98 1.5E-30 T 28-03-2018 A6A12_RS02095 d2d9724b1d2f7f77f6ef157b4871bc7e 98 Pfam PF07876 Stress responsive A/B Barrel Domain 2 97 1.1E-27 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel A6A12_RS13555 d36c0c3f4e719bdff50f4574f4302da6 288 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 288 6.1E-117 T 28-03-2018 IPR005229 Conserved hypothetical protein CHP00255 A6A12_RS13555 d36c0c3f4e719bdff50f4574f4302da6 288 Pfam PF03755 YicC-like family, N-terminal region 2 154 3.3E-42 T 28-03-2018 IPR013527 YicC-like, N-terminal A6A12_RS13555 d36c0c3f4e719bdff50f4574f4302da6 288 Pfam PF08340 Domain of unknown function (DUF1732) 204 288 6.6E-35 T 28-03-2018 IPR013551 Domain of unknown function DUF1732 A6A12_RS07465 09a609a2ce32de9b72605f9a8928ef1d 525 ProSitePatterns PS01303 BCCT family of transporters signature. 336 345 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 A6A12_RS07465 09a609a2ce32de9b72605f9a8928ef1d 525 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 73 520 1.1E-138 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A6A12_RS07465 09a609a2ce32de9b72605f9a8928ef1d 525 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 33 520 1.1E-175 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A6A12_RS10530 7b9e3f0cb665a228578f3628745711d7 210 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 6 207 2.3E-38 T 28-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 A6A12_RS10530 7b9e3f0cb665a228578f3628745711d7 210 Hamap MF_00233 Outer-membrane lipoprotein LolB [lolB]. 3 208 26.679 T 28-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 A6A12_RS10530 7b9e3f0cb665a228578f3628745711d7 210 Gene3D G3DSA:2.50.20.10 24 209 1.2E-48 T 28-03-2018 A6A12_RS10530 7b9e3f0cb665a228578f3628745711d7 210 Pfam PF03550 Outer membrane lipoprotein LolB 46 206 4.2E-44 T 28-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 A6A12_RS10530 7b9e3f0cb665a228578f3628745711d7 210 SUPERFAMILY SSF89392 19 208 3.92E-47 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX A6A12_RS14165 2c571def14ce0d19d537541a3ba4fa92 288 SUPERFAMILY SSF109604 20 264 2.89E-54 T 28-03-2018 A6A12_RS14165 2c571def14ce0d19d537541a3ba4fa92 288 Pfam PF08668 HDOD domain 28 219 4.6E-51 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD A6A12_RS14165 2c571def14ce0d19d537541a3ba4fa92 288 Gene3D G3DSA:1.10.3210.10 7 283 8.6E-36 T 28-03-2018 A6A12_RS06975 a9da1e997a27b8ceb0cd51c41c1cd59d 368 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 8 365 2.2E-159 T 28-03-2018 IPR010162 Peptidase M20B, peptidase T-like A6A12_RS06975 a9da1e997a27b8ceb0cd51c41c1cd59d 368 SUPERFAMILY SSF55031 177 289 3.53E-21 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A6A12_RS06975 a9da1e997a27b8ceb0cd51c41c1cd59d 368 Pfam PF01546 Peptidase family M20/M25/M40 73 367 1.4E-20 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 A6A12_RS06975 a9da1e997a27b8ceb0cd51c41c1cd59d 368 Gene3D G3DSA:3.40.630.10 1 368 8.5E-62 T 28-03-2018 A6A12_RS06975 a9da1e997a27b8ceb0cd51c41c1cd59d 368 PIRSF PIRSF001123 6 105 0.015 T 28-03-2018 IPR008007 Peptidase M42 A6A12_RS06975 a9da1e997a27b8ceb0cd51c41c1cd59d 368 PIRSF PIRSF001123 101 182 1.4E-5 T 28-03-2018 IPR008007 Peptidase M42 A6A12_RS06975 a9da1e997a27b8ceb0cd51c41c1cd59d 368 PIRSF PIRSF001123 224 368 0.0015 T 28-03-2018 IPR008007 Peptidase M42 A6A12_RS06975 a9da1e997a27b8ceb0cd51c41c1cd59d 368 Pfam PF07687 Peptidase dimerisation domain 182 258 3.0E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain A6A12_RS06975 a9da1e997a27b8ceb0cd51c41c1cd59d 368 SUPERFAMILY SSF53187 7 175 1.76E-58 T 28-03-2018 A6A12_RS06975 a9da1e997a27b8ceb0cd51c41c1cd59d 368 SUPERFAMILY SSF53187 287 367 1.76E-58 T 28-03-2018 A6A12_RS08660 1058d061a92b892070217fe182c6c6ee 120 Gene3D G3DSA:1.10.10.10 60 116 3.6E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS08660 1058d061a92b892070217fe182c6c6ee 120 Gene3D G3DSA:1.10.10.10 1 58 0.0019 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS08735 d76ce7f2f1d31b1743b285bbe23a42ab 412 Gene3D G3DSA:1.10.443.10 211 392 9.8E-26 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS08735 d76ce7f2f1d31b1743b285bbe23a42ab 412 SUPERFAMILY SSF56349 106 386 1.85E-60 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS08735 d76ce7f2f1d31b1743b285bbe23a42ab 412 Pfam PF00589 Phage integrase family 214 377 8.5E-22 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS08735 d76ce7f2f1d31b1743b285bbe23a42ab 412 Gene3D G3DSA:1.10.150.130 95 210 2.2E-21 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A6A12_RS08735 d76ce7f2f1d31b1743b285bbe23a42ab 412 Pfam PF13356 Arm DNA-binding domain 8 92 1.8E-15 T 28-03-2018 IPR025166 Integrase, DNA-binding domain A6A12_RS08735 d76ce7f2f1d31b1743b285bbe23a42ab 412 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 106 153 4.9E-7 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A6A12_RS03270 71c9f6c76b9f83184adb6397c058c3fd 555 Gene3D G3DSA:3.40.50.300 290 553 3.7E-58 T 28-03-2018 A6A12_RS03270 71c9f6c76b9f83184adb6397c058c3fd 555 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 553 1.4E-290 T 28-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD A6A12_RS03270 71c9f6c76b9f83184adb6397c058c3fd 555 Pfam PF00005 ABC transporter 340 473 4.2E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS03270 71c9f6c76b9f83184adb6397c058c3fd 555 Pfam PF00005 ABC transporter 22 191 8.3E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS03270 71c9f6c76b9f83184adb6397c058c3fd 555 SUPERFAMILY SSF52540 9 243 4.57E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03270 71c9f6c76b9f83184adb6397c058c3fd 555 Gene3D G3DSA:3.40.50.300 8 289 4.0E-56 T 28-03-2018 A6A12_RS03270 71c9f6c76b9f83184adb6397c058c3fd 555 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS03270 71c9f6c76b9f83184adb6397c058c3fd 555 SUPERFAMILY SSF52540 302 530 2.48E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS03270 71c9f6c76b9f83184adb6397c058c3fd 555 SMART SM00382 348 522 1.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS03270 71c9f6c76b9f83184adb6397c058c3fd 555 SMART SM00382 31 236 2.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS03270 71c9f6c76b9f83184adb6397c058c3fd 555 Pfam PF12848 ABC transporter 230 306 1.7E-13 T 28-03-2018 IPR032781 ABC-transporter extension domain A6A12_RS12880 b23336427ecf9fe46fd4adf53bfb77cf 305 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 13 296 3.2E-100 T 28-03-2018 A6A12_RS12880 b23336427ecf9fe46fd4adf53bfb77cf 305 Pfam PF01040 UbiA prenyltransferase family 21 274 9.8E-38 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A6A12_RS12880 b23336427ecf9fe46fd4adf53bfb77cf 305 PIRSF PIRSF005355 1 303 3.0E-84 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 A6A12_RS12880 b23336427ecf9fe46fd4adf53bfb77cf 305 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 4 298 20.765 T 28-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A6A12_RS13710 934b6d75ab23bc054c2f653d24b09cab 655 SUPERFAMILY SSF81345 7 323 2.62E-54 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A6A12_RS13710 934b6d75ab23bc054c2f653d24b09cab 655 SUPERFAMILY SSF81345 344 650 8.37E-62 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A6A12_RS13710 934b6d75ab23bc054c2f653d24b09cab 655 Pfam PF01032 FecCD transport family 13 323 2.3E-59 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A6A12_RS13710 934b6d75ab23bc054c2f653d24b09cab 655 Pfam PF01032 FecCD transport family 370 650 6.6E-67 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 A6A12_RS13710 934b6d75ab23bc054c2f653d24b09cab 655 Gene3D G3DSA:1.10.3470.10 2 331 1.1E-39 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A6A12_RS13710 934b6d75ab23bc054c2f653d24b09cab 655 Gene3D G3DSA:1.10.3470.10 336 655 6.1E-46 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A6A12_RS04515 c3e339794336cf9164a48df36b84b418 183 Pfam PF17323 Trans-membrane regulatory protein ToxS 33 181 3.7E-71 T 28-03-2018 IPR035288 Trans-membrane regulatory protein ToxS GO:0016021 A6A12_RS04515 c3e339794336cf9164a48df36b84b418 183 ProDom PD016359 TRANSMEMBRANE TOXS REGULATORY MEMBRANE PERIPLASMIC 13 183 8.0E-86 T 28-03-2018 IPR035288 Trans-membrane regulatory protein ToxS GO:0016021 A6A12_RS04980 2fc584daaec2d88634c73825cd1bbea1 616 Gene3D G3DSA:3.90.226.10 319 611 3.1E-52 T 28-03-2018 A6A12_RS04980 2fc584daaec2d88634c73825cd1bbea1 616 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 16 608 3.6E-190 T 28-03-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 A6A12_RS04980 2fc584daaec2d88634c73825cd1bbea1 616 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 327 540 3.4E-53 T 28-03-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 A6A12_RS04980 2fc584daaec2d88634c73825cd1bbea1 616 Pfam PF01343 Peptidase family S49 391 541 5.9E-47 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 A6A12_RS04980 2fc584daaec2d88634c73825cd1bbea1 616 Pfam PF01343 Peptidase family S49 138 292 2.3E-29 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 A6A12_RS04980 2fc584daaec2d88634c73825cd1bbea1 616 PIRSF PIRSF001217 8 616 4.8E-225 T 28-03-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 A6A12_RS04980 2fc584daaec2d88634c73825cd1bbea1 616 SUPERFAMILY SSF52096 209 284 1.49E-26 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS04980 2fc584daaec2d88634c73825cd1bbea1 616 SUPERFAMILY SSF52096 47 178 1.49E-26 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS04980 2fc584daaec2d88634c73825cd1bbea1 616 SUPERFAMILY SSF52096 319 439 3.44E-42 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS04980 2fc584daaec2d88634c73825cd1bbea1 616 SUPERFAMILY SSF52096 467 529 3.44E-42 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS04980 2fc584daaec2d88634c73825cd1bbea1 616 Gene3D G3DSA:3.40.1750.10 186 291 8.8E-21 T 28-03-2018 A6A12_RS11115 d765b951101cf6d07687dff961be1ad9 192 Gene3D G3DSA:1.10.4060.10 117 191 7.0E-6 T 28-03-2018 A6A12_RS11115 d765b951101cf6d07687dff961be1ad9 192 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 4 134 4.8E-13 T 28-03-2018 IPR003111 Lon, substrate-binding domain A6A12_RS11115 d765b951101cf6d07687dff961be1ad9 192 SUPERFAMILY SSF88697 4 189 6.46E-43 T 28-03-2018 IPR015947 PUA-like domain A6A12_RS11115 d765b951101cf6d07687dff961be1ad9 192 Gene3D G3DSA:2.30.130.40 2 111 1.1E-22 T 28-03-2018 A6A12_RS11115 d765b951101cf6d07687dff961be1ad9 192 SMART SM00464 4 190 4.9E-4 T 28-03-2018 IPR003111 Lon, substrate-binding domain A6A12_RS10355 684207c7d437babdcfdaf396f0f96dbd 730 Gene3D G3DSA:1.10.443.10 187 544 4.1E-13 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS10355 684207c7d437babdcfdaf396f0f96dbd 730 Pfam PF00589 Phage integrase family 350 538 5.2E-7 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS10355 684207c7d437babdcfdaf396f0f96dbd 730 SUPERFAMILY SSF56349 350 541 2.59E-9 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS04820 580a37a612545f28c07a49e0faf6e1ac 358 ProSitePatterns PS01215 Mrp family signature. 201 217 - T 28-03-2018 IPR000808 Mrp, conserved site GO:0005524 A6A12_RS04820 580a37a612545f28c07a49e0faf6e1ac 358 Gene3D G3DSA:3.40.50.300 79 316 1.2E-63 T 28-03-2018 A6A12_RS04820 580a37a612545f28c07a49e0faf6e1ac 358 SUPERFAMILY SSF52540 96 342 4.22E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS04820 580a37a612545f28c07a49e0faf6e1ac 358 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 94 337 1.2E-99 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A6A12_RS04820 580a37a612545f28c07a49e0faf6e1ac 358 Hamap MF_02040 Iron-sulfur cluster carrier protein. 89 338 36.144 T 28-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein A6A12_RS03495 cb72d69b7255b01fad0f3ed3a9a91122 173 Hamap MF_01176 HTH-type transcriptional regulator IscR [iscR]. 1 173 49.656 T 28-03-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 A6A12_RS03495 cb72d69b7255b01fad0f3ed3a9a91122 173 SUPERFAMILY SSF46785 2 130 1.69E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03495 cb72d69b7255b01fad0f3ed3a9a91122 173 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 9.5E-47 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type A6A12_RS03495 cb72d69b7255b01fad0f3ed3a9a91122 173 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site A6A12_RS03495 cb72d69b7255b01fad0f3ed3a9a91122 173 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 134 9.2E-65 T 28-03-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 A6A12_RS03495 cb72d69b7255b01fad0f3ed3a9a91122 173 Pfam PF02082 Transcriptional regulator 1 83 1.2E-27 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type A6A12_RS03495 cb72d69b7255b01fad0f3ed3a9a91122 173 Gene3D G3DSA:1.10.10.10 1 139 1.9E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05660 fd0a3ddc29f5abeebef1be44822a8bfa 245 Gene3D G3DSA:3.20.20.70 1 245 3.6E-52 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS05660 fd0a3ddc29f5abeebef1be44822a8bfa 245 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 2 238 1.0E-76 T 28-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A6A12_RS05660 fd0a3ddc29f5abeebef1be44822a8bfa 245 Pfam PF00977 Histidine biosynthesis protein 1 234 2.9E-75 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 A6A12_RS05660 fd0a3ddc29f5abeebef1be44822a8bfa 245 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 1 241 34.637 T 28-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 A6A12_RS05660 fd0a3ddc29f5abeebef1be44822a8bfa 245 SUPERFAMILY SSF51366 1 243 8.07E-64 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 A6A12_RS08060 4926c602a702d488fe48654ebd128209 450 Gene3D G3DSA:1.20.1600.10 128 404 3.8E-11 T 28-03-2018 A6A12_RS08060 4926c602a702d488fe48654ebd128209 450 Gene3D G3DSA:3.90.1170.30 36 127 0.0029 T 28-03-2018 A6A12_RS08060 4926c602a702d488fe48654ebd128209 450 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 34 450 2.1E-119 T 28-03-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 A6A12_RS08060 4926c602a702d488fe48654ebd128209 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 314 335 1.3E-54 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A6A12_RS08060 4926c602a702d488fe48654ebd128209 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 371 394 1.3E-54 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A6A12_RS08060 4926c602a702d488fe48654ebd128209 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 347 371 1.3E-54 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A6A12_RS08060 4926c602a702d488fe48654ebd128209 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 414 429 1.3E-54 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A6A12_RS08060 4926c602a702d488fe48654ebd128209 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 45 68 1.3E-54 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A6A12_RS08060 4926c602a702d488fe48654ebd128209 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 87 107 1.3E-54 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A6A12_RS08060 4926c602a702d488fe48654ebd128209 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 429 449 1.3E-54 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 A6A12_RS08060 4926c602a702d488fe48654ebd128209 450 Pfam PF13437 HlyD family secretion protein 301 417 1.1E-17 T 28-03-2018 A6A12_RS02220 d21c597fa00c2e8f12a1af4afa525a09 246 PIRSF PIRSF003073 1 246 9.4E-64 T 28-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein A6A12_RS02220 d21c597fa00c2e8f12a1af4afa525a09 246 Pfam PF01695 IstB-like ATP binding protein 54 229 4.0E-57 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 A6A12_RS02220 d21c597fa00c2e8f12a1af4afa525a09 246 SUPERFAMILY SSF52540 72 241 5.2E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS02220 d21c597fa00c2e8f12a1af4afa525a09 246 SMART SM00382 97 228 0.0012 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS02220 d21c597fa00c2e8f12a1af4afa525a09 246 Pfam PF08483 IstB-like ATP binding N-terminal 23 50 1.3E-9 T 28-03-2018 IPR013690 IstB-like ATP binding N-terminal A6A12_RS02220 d21c597fa00c2e8f12a1af4afa525a09 246 Gene3D G3DSA:3.40.50.300 3 232 9.4E-16 T 28-03-2018 A6A12_RS05275 16ec8f962ac461c0373cd982e160387d 961 SUPERFAMILY SSF46785 893 957 3.67E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05275 16ec8f962ac461c0373cd982e160387d 961 Pfam PF09397 Ftsk gamma domain 895 954 6.9E-26 T 28-03-2018 IPR018541 FtsK gamma domain A6A12_RS05275 16ec8f962ac461c0373cd982e160387d 961 SMART SM00843 893 958 2.1E-38 T 28-03-2018 IPR018541 FtsK gamma domain A6A12_RS05275 16ec8f962ac461c0373cd982e160387d 961 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 28 199 1.5E-41 T 28-03-2018 IPR025199 DNA translocase FtsK, 4TM region A6A12_RS05275 16ec8f962ac461c0373cd982e160387d 961 Gene3D G3DSA:3.40.50.300 346 827 7.9E-54 T 28-03-2018 A6A12_RS05275 16ec8f962ac461c0373cd982e160387d 961 SUPERFAMILY SSF52540 550 862 9.29E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05275 16ec8f962ac461c0373cd982e160387d 961 Gene3D G3DSA:1.10.10.10 895 949 3.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05275 16ec8f962ac461c0373cd982e160387d 961 Pfam PF01580 FtsK/SpoIIIE family 576 789 2.1E-71 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 A6A12_RS02060 8afd7ff901c0dda74cf2b49373129bf5 137 SUPERFAMILY SSF75620 7 118 1.18E-11 T 28-03-2018 A6A12_RS02060 8afd7ff901c0dda74cf2b49373129bf5 137 Pfam PF00472 RF-1 domain 7 126 2.4E-22 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A6A12_RS02060 8afd7ff901c0dda74cf2b49373129bf5 137 Gene3D G3DSA:3.30.160.20 1 137 5.1E-36 T 28-03-2018 A6A12_RS02060 8afd7ff901c0dda74cf2b49373129bf5 137 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 Gene3D G3DSA:3.30.230.10 584 771 3.2E-70 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 Gene3D G3DSA:2.30.130.40 1 117 8.3E-31 T 28-03-2018 A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 SUPERFAMILY SSF88697 10 200 6.71E-48 T 28-03-2018 IPR015947 PUA-like domain A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 570 771 7.3E-97 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 675 683 - T 28-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 SUPERFAMILY SSF52540 312 584 6.27E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 SUPERFAMILY SSF54211 594 769 1.25E-58 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 Gene3D G3DSA:1.10.8.60 505 583 1.1E-31 T 28-03-2018 A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 10 196 1.3E-41 T 28-03-2018 IPR003111 Lon, substrate-binding domain A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 Hamap MF_01973 Lon protease [lon]. 11 771 71.261 T 28-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 TIGRFAM TIGR00763 lon: endopeptidase La 12 770 9.5E-304 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 702 721 6.5E-56 T 28-03-2018 A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 355 374 6.5E-56 T 28-03-2018 A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 672 691 6.5E-56 T 28-03-2018 A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 725 743 6.5E-56 T 28-03-2018 A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 594 610 6.5E-56 T 28-03-2018 A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 351 488 2.1E-16 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 Gene3D G3DSA:3.40.50.300 286 504 1.4E-28 T 28-03-2018 A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 SMART SM00464 10 201 9.2E-76 T 28-03-2018 IPR003111 Lon, substrate-binding domain A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 SMART SM00382 347 491 4.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 PIRSF PIRSF001174 1 774 0.0 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 A6A12_RS05200 1635cf576770af3aa96494593eec9501 783 Gene3D G3DSA:1.10.4060.10 121 210 2.1E-28 T 28-03-2018 A6A12_RS03580 ba66ebe71964c1503473db991fbfed4a 84 Pfam PF07191 zinc-ribbons 15 78 3.8E-25 T 28-03-2018 IPR010807 Protein of unknown function DUF1407 A6A12_RS03580 ba66ebe71964c1503473db991fbfed4a 84 ProDom PD060428 YFGJ CYTOPLASMIC VP0614 ECS3372 VC0765 YPO2873 Y1359 STY2763A VV0773 16 78 6.0E-22 T 28-03-2018 IPR010807 Protein of unknown function DUF1407 A6A12_RS03580 ba66ebe71964c1503473db991fbfed4a 84 SUPERFAMILY SSF161187 13 80 3.92E-24 T 28-03-2018 IPR029037 YfgJ-like A6A12_RS03580 ba66ebe71964c1503473db991fbfed4a 84 Gene3D G3DSA:2.10.290.10 4 81 0.0019 T 28-03-2018 A6A12_RS01210 9a7e0f49861c716a388b7366af7c6921 212 Pfam PF13972 Bacterial transcriptional repressor 57 199 2.9E-42 T 28-03-2018 IPR025722 Bacterial transcriptional repressor TetR A6A12_RS01210 9a7e0f49861c716a388b7366af7c6921 212 Gene3D G3DSA:1.10.357.10 2 211 8.6E-26 T 28-03-2018 A6A12_RS01210 9a7e0f49861c716a388b7366af7c6921 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 5.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A6A12_RS01210 9a7e0f49861c716a388b7366af7c6921 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 5.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A6A12_RS01210 9a7e0f49861c716a388b7366af7c6921 212 SUPERFAMILY SSF46689 3 73 4.51E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS01210 9a7e0f49861c716a388b7366af7c6921 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 52 2.3E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A6A12_RS11005 ca2bb2bc034ff882c95741ec2d596a25 146 Gene3D G3DSA:2.40.70.10 3 133 2.2E-37 T 28-03-2018 IPR021109 Aspartic peptidase domain A6A12_RS11005 ca2bb2bc034ff882c95741ec2d596a25 146 Pfam PF05618 Putative ATP-dependant zinc protease 6 140 4.3E-45 T 28-03-2018 A6A12_RS11005 ca2bb2bc034ff882c95741ec2d596a25 146 SUPERFAMILY SSF50630 6 140 6.75E-44 T 28-03-2018 IPR021109 Aspartic peptidase domain A6A12_RS11290 d88d24fcae7efe9e160d6d0eb0d2b78d 326 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 102 310 1.1E-83 T 28-03-2018 A6A12_RS11290 d88d24fcae7efe9e160d6d0eb0d2b78d 326 Gene3D G3DSA:3.40.50.1000 165 310 3.0E-27 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS11290 d88d24fcae7efe9e160d6d0eb0d2b78d 326 Gene3D G3DSA:1.10.150.210 130 164 1.6E-24 T 28-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 A6A12_RS11290 d88d24fcae7efe9e160d6d0eb0d2b78d 326 SUPERFAMILY SSF56784 103 310 2.44E-48 T 28-03-2018 IPR023214 HAD-like domain A6A12_RS11290 d88d24fcae7efe9e160d6d0eb0d2b78d 326 Gene3D G3DSA:3.30.70.260 86 129 3.5E-5 T 28-03-2018 A6A12_RS11290 d88d24fcae7efe9e160d6d0eb0d2b78d 326 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 107 277 1.8E-25 T 28-03-2018 A6A12_RS11290 d88d24fcae7efe9e160d6d0eb0d2b78d 326 Pfam PF00702 haloacid dehalogenase-like hydrolase 107 279 1.5E-15 T 28-03-2018 A6A12_RS07540 f5c1dfab76730abd7436f709c948759d 169 Pfam PF06228 Haem utilisation ChuX/HutX 24 161 4.9E-36 T 28-03-2018 IPR010413 Heme utilization carrier protein HutX-like A6A12_RS07540 f5c1dfab76730abd7436f709c948759d 169 Gene3D G3DSA:3.40.1570.10 4 169 1.1E-46 T 28-03-2018 A6A12_RS07540 f5c1dfab76730abd7436f709c948759d 169 SUPERFAMILY SSF144064 2 164 1.02E-57 T 28-03-2018 A6A12_RS07540 f5c1dfab76730abd7436f709c948759d 169 PIRSF PIRSF030840 2 167 2.4E-64 T 28-03-2018 IPR010413 Heme utilization carrier protein HutX-like A6A12_RS07540 f5c1dfab76730abd7436f709c948759d 169 TIGRFAM TIGR04108 HutX: putative heme utilization carrier protein HutX 8 161 1.7E-65 T 28-03-2018 IPR010413 Heme utilization carrier protein HutX-like A6A12_RS13090 3ee633c7771bdf924266317bec63e646 149 Gene3D G3DSA:3.40.50.9100 2 149 1.0E-67 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A6A12_RS13090 3ee633c7771bdf924266317bec63e646 149 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 149 74.024 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A6A12_RS13090 3ee633c7771bdf924266317bec63e646 149 PIRSF PIRSF001399 3 149 3.0E-59 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A6A12_RS13090 3ee633c7771bdf924266317bec63e646 149 Pfam PF01220 Dehydroquinase class II 6 142 1.5E-61 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A6A12_RS13090 3ee633c7771bdf924266317bec63e646 149 SUPERFAMILY SSF52304 4 145 1.7E-61 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A6A12_RS13090 3ee633c7771bdf924266317bec63e646 149 ProSitePatterns PS01029 Dehydroquinase class II signature. 10 27 - T 28-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A6A12_RS13090 3ee633c7771bdf924266317bec63e646 149 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 21 137 5.0E-58 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A6A12_RS13090 3ee633c7771bdf924266317bec63e646 149 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 6 145 9.3E-65 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 A6A12_RS09140 b4cbda8997e85e6c67b6aa31876f596a 435 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 228 411 6.6E-34 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS09140 b4cbda8997e85e6c67b6aa31876f596a 435 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 1.2E-28 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 A6A12_RS09140 b4cbda8997e85e6c67b6aa31876f596a 435 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 433 40.157 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A6A12_RS09140 b4cbda8997e85e6c67b6aa31876f596a 435 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 428 1.9E-168 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A6A12_RS09140 b4cbda8997e85e6c67b6aa31876f596a 435 Gene3D G3DSA:3.30.930.10 107 435 3.8E-95 T 28-03-2018 A6A12_RS09140 b4cbda8997e85e6c67b6aa31876f596a 435 PRINTS PR00981 Seryl-tRNA synthetase signature 327 340 3.7E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A6A12_RS09140 b4cbda8997e85e6c67b6aa31876f596a 435 PRINTS PR00981 Seryl-tRNA synthetase signature 275 287 3.7E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A6A12_RS09140 b4cbda8997e85e6c67b6aa31876f596a 435 PRINTS PR00981 Seryl-tRNA synthetase signature 344 360 3.7E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A6A12_RS09140 b4cbda8997e85e6c67b6aa31876f596a 435 PRINTS PR00981 Seryl-tRNA synthetase signature 287 300 3.7E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A6A12_RS09140 b4cbda8997e85e6c67b6aa31876f596a 435 PRINTS PR00981 Seryl-tRNA synthetase signature 362 378 3.7E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A6A12_RS09140 b4cbda8997e85e6c67b6aa31876f596a 435 SUPERFAMILY SSF55681 118 429 4.23E-99 T 28-03-2018 A6A12_RS09140 b4cbda8997e85e6c67b6aa31876f596a 435 Gene3D G3DSA:1.10.287.40 2 106 4.8E-23 T 28-03-2018 A6A12_RS09140 b4cbda8997e85e6c67b6aa31876f596a 435 PIRSF PIRSF001529 1 435 5.2E-184 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A6A12_RS09140 b4cbda8997e85e6c67b6aa31876f596a 435 SUPERFAMILY SSF46589 1 114 3.77E-27 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 A6A12_RS13590 7412509e1d45a68b2014aea9c45171f2 235 Pfam PF06992 Replication protein P 40 122 3.1E-14 T 28-03-2018 IPR009731 Replication P GO:0006270 A6A12_RS09965 8b720c44fea8c3ef110ced305d306b52 757 Pfam PF02421 Ferrous iron transport protein B 4 161 1.2E-56 T 28-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 A6A12_RS09965 8b720c44fea8c3ef110ced305d306b52 757 Pfam PF07664 Ferrous iron transport protein B C terminus 452 504 1.1E-18 T 28-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 A6A12_RS09965 8b720c44fea8c3ef110ced305d306b52 757 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 154 2.3E-12 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A6A12_RS09965 8b720c44fea8c3ef110ced305d306b52 757 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 9 686 4.6E-178 T 28-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 A6A12_RS09965 8b720c44fea8c3ef110ced305d306b52 757 Pfam PF07670 Nucleoside recognition 349 440 1.6E-13 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A6A12_RS09965 8b720c44fea8c3ef110ced305d306b52 757 Pfam PF07670 Nucleoside recognition 509 689 5.1E-38 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A6A12_RS09965 8b720c44fea8c3ef110ced305d306b52 757 Gene3D G3DSA:3.40.50.300 2 293 3.4E-33 T 28-03-2018 A6A12_RS09965 8b720c44fea8c3ef110ced305d306b52 757 SUPERFAMILY SSF52540 4 176 1.0E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS02945 4c298b5ec8df0289736cc846e23f8cf1 111 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 73 2.4E-26 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A6A12_RS02945 4c298b5ec8df0289736cc846e23f8cf1 111 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 3.7E-45 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A6A12_RS02945 4c298b5ec8df0289736cc846e23f8cf1 111 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 3.7E-45 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A6A12_RS02945 4c298b5ec8df0289736cc846e23f8cf1 111 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 3.7E-45 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A6A12_RS02945 4c298b5ec8df0289736cc846e23f8cf1 111 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 3.7E-45 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A6A12_RS02945 4c298b5ec8df0289736cc846e23f8cf1 111 Pfam PF03840 Preprotein translocase SecG subunit 4 72 2.0E-22 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 A6A12_RS09170 1f1447013778b50c7deb338ee71c508c 314 Gene3D G3DSA:1.10.3470.10 3 288 2.8E-30 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A6A12_RS09170 1f1447013778b50c7deb338ee71c508c 314 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 272 7.4E-26 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A6A12_RS12595 37ea951219b7657c0c69052c3440d5ce 264 SMART SM01150 3 262 5.1E-117 T 28-03-2018 IPR009770 Domain of unknown function DUF1338 A6A12_RS12595 37ea951219b7657c0c69052c3440d5ce 264 Pfam PF07063 Domain of unknown function (DUF1338) 134 261 6.9E-29 T 28-03-2018 IPR009770 Domain of unknown function DUF1338 A6A12_RS12595 37ea951219b7657c0c69052c3440d5ce 264 Pfam PF07063 Domain of unknown function (DUF1338) 30 116 2.6E-20 T 28-03-2018 IPR009770 Domain of unknown function DUF1338 A6A12_RS13385 36af2896367f62f28fe0eaf7ca3dc813 371 TIGRFAM TIGR04371 methyltran_NanM: putative sugar O-methyltransferase 108 244 2.5E-24 T 28-03-2018 IPR030807 Putative sugar O-methyltransferase A6A12_RS13385 36af2896367f62f28fe0eaf7ca3dc813 371 Pfam PF13489 Methyltransferase domain 115 276 4.4E-7 T 28-03-2018 A6A12_RS13385 36af2896367f62f28fe0eaf7ca3dc813 371 SUPERFAMILY SSF53335 67 245 1.59E-9 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS13385 36af2896367f62f28fe0eaf7ca3dc813 371 Gene3D G3DSA:3.40.50.150 38 369 1.1E-8 T 28-03-2018 A6A12_RS01745 3fb8f2659e88102d1a1e8f0235c79571 468 Pfam PF13520 Amino acid permease 5 411 1.6E-68 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A6A12_RS01745 3fb8f2659e88102d1a1e8f0235c79571 468 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 3 466 2.1E-166 T 28-03-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 A6A12_RS01745 3fb8f2659e88102d1a1e8f0235c79571 468 PIRSF PIRSF006060 1 467 3.1E-45 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 A6A12_RS00805 e9dca57020d0f0bb1987b4e9284d7b1f 193 Pfam PF13511 Domain of unknown function (DUF4124) 24 68 2.3E-10 T 28-03-2018 IPR025392 Domain of unknown function DUF4124 A6A12_RS01435 336090e3471b262dcee821f7cfe9d021 153 Gene3D G3DSA:3.40.1550.10 1 153 2.1E-31 T 28-03-2018 IPR028976 CheC-like domain A6A12_RS01435 336090e3471b262dcee821f7cfe9d021 153 SUPERFAMILY SSF103039 1 153 3.01E-36 T 28-03-2018 IPR028976 CheC-like domain A6A12_RS01435 336090e3471b262dcee821f7cfe9d021 153 Pfam PF13690 Chemotaxis phosphatase CheX 42 140 1.2E-20 T 28-03-2018 IPR028051 Chemotaxis phosphatase CheX-like domain A6A12_RS14045 8b47125e59aeda7e0c7c7b5bfa128deb 205 SUPERFAMILY SSF46626 115 203 7.35E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS14045 8b47125e59aeda7e0c7c7b5bfa128deb 205 Gene3D G3DSA:1.10.760.10 15 103 5.9E-22 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS14045 8b47125e59aeda7e0c7c7b5bfa128deb 205 Gene3D G3DSA:1.10.760.10 104 202 1.2E-23 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS14045 8b47125e59aeda7e0c7c7b5bfa128deb 205 PIRSF PIRSF000005 1 205 6.3E-62 T 28-03-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 A6A12_RS14045 8b47125e59aeda7e0c7c7b5bfa128deb 205 Pfam PF00034 Cytochrome c 25 104 4.6E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS14045 8b47125e59aeda7e0c7c7b5bfa128deb 205 Pfam PF00034 Cytochrome c 117 201 2.1E-8 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS14045 8b47125e59aeda7e0c7c7b5bfa128deb 205 SUPERFAMILY SSF46626 6 104 6.8E-21 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 A6A12_RS14045 8b47125e59aeda7e0c7c7b5bfa128deb 205 PRINTS PR00605 Class IC cytochrome C signature 30 41 4.5E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 A6A12_RS14045 8b47125e59aeda7e0c7c7b5bfa128deb 205 PRINTS PR00605 Class IC cytochrome C signature 79 101 4.5E-5 T 28-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 A6A12_RS08130 622b13c4482773853fa0eeb211cc182e 98 Gene3D G3DSA:4.10.520.10 1 98 7.1E-34 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A6A12_RS08130 622b13c4482773853fa0eeb211cc182e 98 SUPERFAMILY SSF47729 3 95 1.06E-32 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 A6A12_RS08130 622b13c4482773853fa0eeb211cc182e 98 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 1 97 30.347 T 28-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 A6A12_RS08130 622b13c4482773853fa0eeb211cc182e 98 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 A6A12_RS08130 622b13c4482773853fa0eeb211cc182e 98 Pfam PF00216 Bacterial DNA-binding protein 3 91 4.9E-32 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS08130 622b13c4482773853fa0eeb211cc182e 98 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 2 95 1.3E-50 T 28-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 A6A12_RS08130 622b13c4482773853fa0eeb211cc182e 98 SMART SM00411 3 92 6.8E-42 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS08130 622b13c4482773853fa0eeb211cc182e 98 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 5.9E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS08130 622b13c4482773853fa0eeb211cc182e 98 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 5.9E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS08130 622b13c4482773853fa0eeb211cc182e 98 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 5.9E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 A6A12_RS02910 c10218a9d790d379ddb7c4d3db2a9710 330 SUPERFAMILY SSF56935 23 330 2.09E-57 T 28-03-2018 A6A12_RS02910 c10218a9d790d379ddb7c4d3db2a9710 330 Pfam PF13609 Gram-negative porin 9 305 6.3E-30 T 28-03-2018 A6A12_RS02910 c10218a9d790d379ddb7c4d3db2a9710 330 Gene3D G3DSA:2.40.160.10 5 330 5.0E-42 T 28-03-2018 A6A12_RS13430 7b369d039f229f2dec1c0e06b1090bdc 412 Pfam PF04932 O-Antigen ligase 182 341 6.1E-15 T 28-03-2018 IPR007016 O-antigen ligase-related A6A12_RS06410 6d6bfd960d24eaca6b9198acd5f8d4bd 375 ProSitePatterns PS00480 Citrate synthase signature. 258 270 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 A6A12_RS06410 6d6bfd960d24eaca6b9198acd5f8d4bd 375 PIRSF PIRSF001369 6 375 2.2E-112 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type A6A12_RS06410 6d6bfd960d24eaca6b9198acd5f8d4bd 375 Gene3D G3DSA:1.10.580.10 15 263 3.6E-75 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain A6A12_RS06410 6d6bfd960d24eaca6b9198acd5f8d4bd 375 Pfam PF00285 Citrate synthase, C-terminal domain 10 357 2.8E-112 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS06410 6d6bfd960d24eaca6b9198acd5f8d4bd 375 PRINTS PR00143 Citrate synthase signature 176 191 2.5E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS06410 6d6bfd960d24eaca6b9198acd5f8d4bd 375 PRINTS PR00143 Citrate synthase signature 328 342 2.5E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS06410 6d6bfd960d24eaca6b9198acd5f8d4bd 375 PRINTS PR00143 Citrate synthase signature 198 226 2.5E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS06410 6d6bfd960d24eaca6b9198acd5f8d4bd 375 PRINTS PR00143 Citrate synthase signature 125 138 2.5E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS06410 6d6bfd960d24eaca6b9198acd5f8d4bd 375 PRINTS PR00143 Citrate synthase signature 308 324 2.5E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS06410 6d6bfd960d24eaca6b9198acd5f8d4bd 375 PRINTS PR00143 Citrate synthase signature 251 271 2.5E-36 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS06410 6d6bfd960d24eaca6b9198acd5f8d4bd 375 Gene3D G3DSA:1.10.580.10 303 355 4.0E-9 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain A6A12_RS06410 6d6bfd960d24eaca6b9198acd5f8d4bd 375 SUPERFAMILY SSF48256 9 375 6.54E-122 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 A6A12_RS06410 6d6bfd960d24eaca6b9198acd5f8d4bd 375 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 10 375 5.7E-160 T 28-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 A6A12_RS08305 64bf8e738d9266026c7e6a46d8b231da 505 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 276 283 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 A6A12_RS08305 64bf8e738d9266026c7e6a46d8b231da 505 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 52 497 8.4E-205 T 28-03-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 A6A12_RS08305 64bf8e738d9266026c7e6a46d8b231da 505 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 304 315 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 A6A12_RS08305 64bf8e738d9266026c7e6a46d8b231da 505 Gene3D G3DSA:3.40.309.10 295 485 4.5E-66 T 28-03-2018 A6A12_RS08305 64bf8e738d9266026c7e6a46d8b231da 505 SUPERFAMILY SSF53720 15 501 5.11E-164 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 A6A12_RS08305 64bf8e738d9266026c7e6a46d8b231da 505 Gene3D G3DSA:3.40.605.10 28 294 4.4E-100 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 A6A12_RS08305 64bf8e738d9266026c7e6a46d8b231da 505 Pfam PF00171 Aldehyde dehydrogenase family 45 498 1.2E-163 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 3.4E-6 T 28-03-2018 A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 91 108 3.4E-6 T 28-03-2018 A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 3.4E-6 T 28-03-2018 A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 Gene3D G3DSA:3.40.50.880 1 192 6.4E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 4.2E-13 T 28-03-2018 A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 4.2E-13 T 28-03-2018 A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 4.2E-13 T 28-03-2018 A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 PRINTS PR00097 Anthranilate synthase component II signature 99 107 3.4E-36 T 28-03-2018 A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 PRINTS PR00097 Anthranilate synthase component II signature 119 131 3.4E-36 T 28-03-2018 A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 PRINTS PR00097 Anthranilate synthase component II signature 2 16 3.4E-36 T 28-03-2018 A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 PRINTS PR00097 Anthranilate synthase component II signature 74 85 3.4E-36 T 28-03-2018 A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 PRINTS PR00097 Anthranilate synthase component II signature 47 56 3.4E-36 T 28-03-2018 A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 PRINTS PR00097 Anthranilate synthase component II signature 169 182 3.4E-36 T 28-03-2018 A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 192 1.4E-86 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 SUPERFAMILY SSF52317 1 191 2.57E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS12615 0b6f1b4bd9ffaefe11308ba2029519a7 192 Pfam PF00117 Glutamine amidotransferase class-I 4 190 7.0E-55 T 28-03-2018 IPR017926 Glutamine amidotransferase A6A12_RS04990 9ad9a8da2d563b8d84a3b1f5898b27f0 277 Pfam PF00551 Formyl transferase 82 259 4.0E-48 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A6A12_RS04990 9ad9a8da2d563b8d84a3b1f5898b27f0 277 Gene3D G3DSA:3.30.70.260 1 82 2.9E-10 T 28-03-2018 A6A12_RS04990 9ad9a8da2d563b8d84a3b1f5898b27f0 277 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 277 44.678 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A6A12_RS04990 9ad9a8da2d563b8d84a3b1f5898b27f0 277 Pfam PF01842 ACT domain 5 66 8.8E-7 T 28-03-2018 IPR002912 ACT domain A6A12_RS04990 9ad9a8da2d563b8d84a3b1f5898b27f0 277 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 6 32 1.4E-63 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A6A12_RS04990 9ad9a8da2d563b8d84a3b1f5898b27f0 277 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 251 276 1.4E-63 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A6A12_RS04990 9ad9a8da2d563b8d84a3b1f5898b27f0 277 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 83 105 1.4E-63 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A6A12_RS04990 9ad9a8da2d563b8d84a3b1f5898b27f0 277 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 38 50 1.4E-63 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A6A12_RS04990 9ad9a8da2d563b8d84a3b1f5898b27f0 277 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 229 251 1.4E-63 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A6A12_RS04990 9ad9a8da2d563b8d84a3b1f5898b27f0 277 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 105 132 1.4E-63 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A6A12_RS04990 9ad9a8da2d563b8d84a3b1f5898b27f0 277 SUPERFAMILY SSF55021 4 55 3.16E-8 T 28-03-2018 A6A12_RS04990 9ad9a8da2d563b8d84a3b1f5898b27f0 277 PIRSF PIRSF036480 1 277 1.1E-111 T 28-03-2018 A6A12_RS04990 9ad9a8da2d563b8d84a3b1f5898b27f0 277 SUPERFAMILY SSF53328 82 276 3.4E-59 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A6A12_RS04990 9ad9a8da2d563b8d84a3b1f5898b27f0 277 Gene3D G3DSA:3.40.50.170 83 277 1.8E-52 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 A6A12_RS04990 9ad9a8da2d563b8d84a3b1f5898b27f0 277 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 5 277 1.1E-121 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 A6A12_RS12765 b27f3ed6dffaad86cfa4a5e6b977958f 194 Gene3D G3DSA:1.10.10.10 10 107 4.7E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS12765 b27f3ed6dffaad86cfa4a5e6b977958f 194 Pfam PF03551 Transcriptional regulator PadR-like family 22 95 7.2E-16 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal A6A12_RS12765 b27f3ed6dffaad86cfa4a5e6b977958f 194 SUPERFAMILY SSF46785 18 193 1.23E-44 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS12765 b27f3ed6dffaad86cfa4a5e6b977958f 194 Pfam PF10400 Virulence activator alpha C-term 107 191 8.9E-13 T 28-03-2018 IPR018309 Transcription regulator PadR, C-terminal A6A12_RS07055 a61c67823a26484897f07ead1335eb6e 379 SUPERFAMILY SSF56672 42 289 1.78E-9 T 28-03-2018 A6A12_RS07055 a61c67823a26484897f07ead1335eb6e 379 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 80 288 3.7E-24 T 28-03-2018 IPR000477 Reverse transcriptase domain A6A12_RS07055 a61c67823a26484897f07ead1335eb6e 379 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 242 253 2.2E-21 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A6A12_RS07055 a61c67823a26484897f07ead1335eb6e 379 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 296 302 2.2E-21 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A6A12_RS07055 a61c67823a26484897f07ead1335eb6e 379 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 209 222 2.2E-21 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A6A12_RS07055 a61c67823a26484897f07ead1335eb6e 379 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 75 88 2.2E-21 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A6A12_RS07055 a61c67823a26484897f07ead1335eb6e 379 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 89 101 2.2E-21 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 A6A12_RS07055 a61c67823a26484897f07ead1335eb6e 379 Gene3D G3DSA:3.30.70.270 99 300 3.1E-26 T 28-03-2018 A6A12_RS01390 172c44b6db02fe4c0a08641ec7d7996e 75 ProSitePatterns PS00057 Ribosomal protein S18 signature. 21 44 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01390 172c44b6db02fe4c0a08641ec7d7996e 75 Gene3D G3DSA:4.10.640.10 1 75 2.8E-32 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01390 172c44b6db02fe4c0a08641ec7d7996e 75 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 73 21.42 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01390 172c44b6db02fe4c0a08641ec7d7996e 75 PRINTS PR00974 Ribosomal protein S18 family signature 46 60 1.6E-18 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01390 172c44b6db02fe4c0a08641ec7d7996e 75 PRINTS PR00974 Ribosomal protein S18 family signature 38 45 1.6E-18 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01390 172c44b6db02fe4c0a08641ec7d7996e 75 PRINTS PR00974 Ribosomal protein S18 family signature 60 70 1.6E-18 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01390 172c44b6db02fe4c0a08641ec7d7996e 75 PRINTS PR00974 Ribosomal protein S18 family signature 28 38 1.6E-18 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01390 172c44b6db02fe4c0a08641ec7d7996e 75 SUPERFAMILY SSF46911 3 74 2.49E-29 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01390 172c44b6db02fe4c0a08641ec7d7996e 75 Pfam PF01084 Ribosomal protein S18 19 68 2.8E-25 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01390 172c44b6db02fe4c0a08641ec7d7996e 75 TIGRFAM TIGR00165 S18: ribosomal protein bS18 4 73 6.2E-38 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS01390 172c44b6db02fe4c0a08641ec7d7996e 75 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 21 73 9.0E-24 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS03090 1bd54c3c1963e1296324f4777db4b986 344 SUPERFAMILY SSF51430 1 344 2.1E-108 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain A6A12_RS03090 1bd54c3c1963e1296324f4777db4b986 344 Pfam PF00248 Aldo/keto reductase family 15 335 1.3E-72 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain A6A12_RS03090 1bd54c3c1963e1296324f4777db4b986 344 Gene3D G3DSA:3.20.20.100 1 344 8.0E-94 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain A6A12_RS05895 d34cb7c59e81d06274328fadc2b1adec 301 SUPERFAMILY SSF64182 1 298 1.44E-66 T 28-03-2018 A6A12_RS05895 d34cb7c59e81d06274328fadc2b1adec 301 Pfam PF02833 DHHA2 domain 180 297 1.5E-15 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A6A12_RS05895 d34cb7c59e81d06274328fadc2b1adec 301 Gene3D G3DSA:3.90.1640.10 1 184 3.4E-53 T 28-03-2018 A6A12_RS05895 d34cb7c59e81d06274328fadc2b1adec 301 SMART SM01131 178 300 8.5E-35 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A6A12_RS05895 d34cb7c59e81d06274328fadc2b1adec 301 Pfam PF01368 DHH family 2 142 5.4E-21 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A6A12_RS07425 b5efa0a0dbe3c7ca91a1c99ac7213262 103 Gene3D G3DSA:3.30.750.24 2 102 1.9E-8 T 28-03-2018 IPR002645 STAS domain A6A12_RS07425 b5efa0a0dbe3c7ca91a1c99ac7213262 103 Pfam PF13466 STAS domain 13 89 1.6E-12 T 28-03-2018 IPR002645 STAS domain A6A12_RS07425 b5efa0a0dbe3c7ca91a1c99ac7213262 103 SUPERFAMILY SSF52091 5 94 8.44E-13 T 28-03-2018 IPR002645 STAS domain A6A12_RS05390 9b58060a828935f73baf3b56c64af815 433 PRINTS PR00173 Glutamate-aspartate symporter signature 346 365 1.5E-54 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS05390 9b58060a828935f73baf3b56c64af815 433 PRINTS PR00173 Glutamate-aspartate symporter signature 21 41 1.5E-54 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS05390 9b58060a828935f73baf3b56c64af815 433 PRINTS PR00173 Glutamate-aspartate symporter signature 92 117 1.5E-54 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS05390 9b58060a828935f73baf3b56c64af815 433 PRINTS PR00173 Glutamate-aspartate symporter signature 209 228 1.5E-54 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS05390 9b58060a828935f73baf3b56c64af815 433 PRINTS PR00173 Glutamate-aspartate symporter signature 244 263 1.5E-54 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS05390 9b58060a828935f73baf3b56c64af815 433 PRINTS PR00173 Glutamate-aspartate symporter signature 372 392 1.5E-54 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS05390 9b58060a828935f73baf3b56c64af815 433 PRINTS PR00173 Glutamate-aspartate symporter signature 62 82 1.5E-54 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS05390 9b58060a828935f73baf3b56c64af815 433 PRINTS PR00173 Glutamate-aspartate symporter signature 311 337 1.5E-54 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS05390 9b58060a828935f73baf3b56c64af815 433 PRINTS PR00173 Glutamate-aspartate symporter signature 161 183 1.5E-54 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS05390 9b58060a828935f73baf3b56c64af815 433 Gene3D G3DSA:1.10.3860.10 12 425 1.4E-112 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS05390 9b58060a828935f73baf3b56c64af815 433 Pfam PF00375 Sodium:dicarboxylate symporter family 29 417 2.6E-117 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS05390 9b58060a828935f73baf3b56c64af815 433 SUPERFAMILY SSF118215 29 417 4.05E-107 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A6A12_RS01950 908dc452357d05f57e4001aa9e805877 317 SUPERFAMILY SSF56059 123 313 2.91E-59 T 28-03-2018 A6A12_RS01950 908dc452357d05f57e4001aa9e805877 317 TIGRFAM TIGR01380 glut_syn: glutathione synthase 2 311 3.6E-139 T 28-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 A6A12_RS01950 908dc452357d05f57e4001aa9e805877 317 Gene3D G3DSA:3.30.470.20 191 300 1.4E-17 T 28-03-2018 A6A12_RS01950 908dc452357d05f57e4001aa9e805877 317 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 124 296 9.7E-81 T 28-03-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 A6A12_RS01950 908dc452357d05f57e4001aa9e805877 317 Hamap MF_00162 Glutathione synthetase [gshB]. 1 316 179.403 T 28-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 A6A12_RS01950 908dc452357d05f57e4001aa9e805877 317 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 2 120 5.7E-47 T 28-03-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 A6A12_RS01950 908dc452357d05f57e4001aa9e805877 317 Gene3D G3DSA:3.40.50.20 2 129 5.6E-52 T 28-03-2018 A6A12_RS01950 908dc452357d05f57e4001aa9e805877 317 Gene3D G3DSA:3.30.1490.20 138 190 9.3E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A6A12_RS01950 908dc452357d05f57e4001aa9e805877 317 SUPERFAMILY SSF52440 2 122 2.76E-46 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A6A12_RS14375 a909fcd6bbd97c2a817942ce1a3b8a03 84 Gene3D G3DSA:1.20.20.10 4 78 1.6E-15 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A6A12_RS14375 a909fcd6bbd97c2a817942ce1a3b8a03 84 PRINTS PR00124 ATP synthase C subunit signature 11 30 1.7E-6 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14375 a909fcd6bbd97c2a817942ce1a3b8a03 84 PRINTS PR00124 ATP synthase C subunit signature 32 47 1.7E-6 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14375 a909fcd6bbd97c2a817942ce1a3b8a03 84 PRINTS PR00124 ATP synthase C subunit signature 49 74 1.7E-6 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14375 a909fcd6bbd97c2a817942ce1a3b8a03 84 ProSitePatterns PS00605 ATP synthase c subunit signature. 39 60 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14375 a909fcd6bbd97c2a817942ce1a3b8a03 84 SUPERFAMILY SSF81333 3 78 1.7E-19 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A6A12_RS14375 a909fcd6bbd97c2a817942ce1a3b8a03 84 Hamap MF_01396 ATP synthase subunit c [atpH]. 9 74 13.874 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 A6A12_RS14375 a909fcd6bbd97c2a817942ce1a3b8a03 84 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 19 76 1.2E-30 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 A6A12_RS14375 a909fcd6bbd97c2a817942ce1a3b8a03 84 Pfam PF00137 ATP synthase subunit C 10 72 1.3E-10 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A6A12_RS09515 39a2dc73aadc1ae5e4b449d72cf0d045 623 Pfam PF01553 Acyltransferase 441 566 6.8E-23 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A6A12_RS09515 39a2dc73aadc1ae5e4b449d72cf0d045 623 SUPERFAMILY SSF69593 398 602 1.44E-27 T 28-03-2018 A6A12_RS09515 39a2dc73aadc1ae5e4b449d72cf0d045 623 Pfam PF07690 Major Facilitator Superfamily 18 310 2.7E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A6A12_RS09515 39a2dc73aadc1ae5e4b449d72cf0d045 623 Gene3D G3DSA:1.20.1250.20 215 419 6.6E-14 T 28-03-2018 A6A12_RS09515 39a2dc73aadc1ae5e4b449d72cf0d045 623 Gene3D G3DSA:1.20.1250.20 2 201 8.0E-10 T 28-03-2018 A6A12_RS09515 39a2dc73aadc1ae5e4b449d72cf0d045 623 SMART SM00563 455 569 2.5E-32 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A6A12_RS09515 39a2dc73aadc1ae5e4b449d72cf0d045 623 SUPERFAMILY SSF103473 14 419 4.97E-26 T 28-03-2018 IPR020846 Major facilitator superfamily domain A6A12_RS09515 39a2dc73aadc1ae5e4b449d72cf0d045 623 Gene3D G3DSA:3.40.1130.10 420 620 2.9E-38 T 28-03-2018 A6A12_RS02595 0b895f37ca4422ebcd5c6ac1e4ec53c4 293 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 17 124 7.0E-33 T 28-03-2018 IPR010627 Peptidase A24A, N-terminal A6A12_RS02595 0b895f37ca4422ebcd5c6ac1e4ec53c4 293 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 212 223 3.7E-29 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial A6A12_RS02595 0b895f37ca4422ebcd5c6ac1e4ec53c4 293 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 143 160 3.7E-29 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial A6A12_RS02595 0b895f37ca4422ebcd5c6ac1e4ec53c4 293 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 201 211 3.7E-29 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial A6A12_RS02595 0b895f37ca4422ebcd5c6ac1e4ec53c4 293 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 224 239 3.7E-29 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial A6A12_RS02595 0b895f37ca4422ebcd5c6ac1e4ec53c4 293 Pfam PF01478 Type IV leader peptidase family 135 244 5.5E-27 T 28-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 A6A12_RS05865 3dc32b1d5efa67ba0b254ed5596b730b 77 TIGRFAM TIGR02647 DNA: TIGR02647 family protein 1 76 5.0E-36 T 28-03-2018 IPR013468 Conserved hypothetical protein CHP02647 A6A12_RS05865 3dc32b1d5efa67ba0b254ed5596b730b 77 Pfam PF06146 Phosphate-starvation-inducible E 9 68 1.4E-8 T 28-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like A6A12_RS06625 e68a35b0a59e868c5cddf3d6cbba48f6 180 PIRSF PIRSF010252 1 175 6.9E-66 T 28-03-2018 IPR009809 Cell division protein ZapC A6A12_RS06625 e68a35b0a59e868c5cddf3d6cbba48f6 180 Hamap MF_00906 Cell division protein ZapC [zapC]. 1 177 35.193 T 28-03-2018 IPR009809 Cell division protein ZapC A6A12_RS06625 e68a35b0a59e868c5cddf3d6cbba48f6 180 Pfam PF07126 Cell-division protein ZapC 1 168 6.3E-63 T 28-03-2018 IPR009809 Cell division protein ZapC A6A12_RS04045 fbb7a2d7c5b0392c905704351496d74e 240 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 50 64 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS04045 fbb7a2d7c5b0392c905704351496d74e 240 SUPERFAMILY SSF55120 2 237 1.47E-63 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS04045 fbb7a2d7c5b0392c905704351496d74e 240 Pfam PF00849 RNA pseudouridylate synthase 10 170 2.2E-31 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS04045 fbb7a2d7c5b0392c905704351496d74e 240 Gene3D G3DSA:3.30.2350.10 1 238 3.2E-61 T 28-03-2018 A6A12_RS09865 1d193b4e8ca0f71c78cdead753b91cec 222 Pfam PF03379 CcmB protein 7 219 3.1E-89 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09865 1d193b4e8ca0f71c78cdead753b91cec 222 PIRSF PIRSF002764 1 222 4.3E-81 T 28-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria A6A12_RS09865 1d193b4e8ca0f71c78cdead753b91cec 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 158 177 5.5E-70 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09865 1d193b4e8ca0f71c78cdead753b91cec 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 103 121 5.5E-70 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09865 1d193b4e8ca0f71c78cdead753b91cec 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 195 218 5.5E-70 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09865 1d193b4e8ca0f71c78cdead753b91cec 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 55 72 5.5E-70 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09865 1d193b4e8ca0f71c78cdead753b91cec 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 78 101 5.5E-70 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09865 1d193b4e8ca0f71c78cdead753b91cec 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 29 50 5.5E-70 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 A6A12_RS09865 1d193b4e8ca0f71c78cdead753b91cec 222 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 8 218 2.7E-91 T 28-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria A6A12_RS08870 f569bbd354105695aee9e9dbc3e20f9e 162 Gene3D G3DSA:3.10.450.50 9 136 2.7E-39 T 28-03-2018 A6A12_RS08870 f569bbd354105695aee9e9dbc3e20f9e 162 SUPERFAMILY SSF103642 142 162 1.8E-7 T 28-03-2018 A6A12_RS08870 f569bbd354105695aee9e9dbc3e20f9e 162 Pfam PF02810 SEC-C motif 145 162 4.8E-9 T 28-03-2018 IPR004027 SEC-C motif A6A12_RS08870 f569bbd354105695aee9e9dbc3e20f9e 162 SUPERFAMILY SSF54427 31 134 3.5E-32 T 28-03-2018 IPR032710 NTF2-like domain A6A12_RS08870 f569bbd354105695aee9e9dbc3e20f9e 162 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 7 133 25.44 T 28-03-2018 IPR023006 Uncharacterised protein family UPF0225 A6A12_RS12710 5e2b21f22bbce88a335bfad9c37d68fc 832 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 65 764 5.7E-173 T 28-03-2018 A6A12_RS12710 5e2b21f22bbce88a335bfad9c37d68fc 832 Pfam PF00905 Penicillin binding protein transpeptidase domain 440 712 8.0E-30 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 A6A12_RS12710 5e2b21f22bbce88a335bfad9c37d68fc 832 Gene3D G3DSA:2.40.50.140 349 426 3.7E-21 T 28-03-2018 A6A12_RS12710 5e2b21f22bbce88a335bfad9c37d68fc 832 Gene3D G3DSA:1.10.3810.10 47 246 2.2E-80 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 A6A12_RS12710 5e2b21f22bbce88a335bfad9c37d68fc 832 Gene3D G3DSA:3.40.710.10 427 782 1.6E-93 T 28-03-2018 A6A12_RS12710 5e2b21f22bbce88a335bfad9c37d68fc 832 SUPERFAMILY SSF53955 43 256 1.8E-78 T 28-03-2018 IPR023346 Lysozyme-like domain A6A12_RS12710 5e2b21f22bbce88a335bfad9c37d68fc 832 Pfam PF00912 Transglycosylase 55 229 2.6E-64 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 A6A12_RS12710 5e2b21f22bbce88a335bfad9c37d68fc 832 Pfam PF17092 Penicillin-binding protein OB-like domain 317 437 1.9E-27 T 28-03-2018 IPR031376 Penicillin-binding protein, OB-like domain A6A12_RS12710 5e2b21f22bbce88a335bfad9c37d68fc 832 SUPERFAMILY SSF56601 434 815 3.38E-116 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A6A12_RS12710 5e2b21f22bbce88a335bfad9c37d68fc 832 SUPERFAMILY SSF56601 211 233 3.38E-116 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A6A12_RS12710 5e2b21f22bbce88a335bfad9c37d68fc 832 SUPERFAMILY SSF56601 262 314 3.38E-116 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A6A12_RS04840 bead04197e5efdd3cf51519365a15582 424 SUPERFAMILY SSF56935 26 424 1.16E-95 T 28-03-2018 A6A12_RS04840 bead04197e5efdd3cf51519365a15582 424 Gene3D G3DSA:2.40.160.60 26 424 4.5E-81 T 28-03-2018 A6A12_RS04840 bead04197e5efdd3cf51519365a15582 424 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 18 424 8.9E-124 T 28-03-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) A6A12_RS13270 52c39559c403e8f35120359ae08e79b4 242 SUPERFAMILY SSF50494 52 215 7.54E-19 T 28-03-2018 IPR009003 Peptidase S1, PA clan A6A12_RS13270 52c39559c403e8f35120359ae08e79b4 242 Pfam PF13365 Trypsin-like peptidase domain 79 178 3.9E-6 T 28-03-2018 A6A12_RS13270 52c39559c403e8f35120359ae08e79b4 242 Gene3D G3DSA:2.40.10.10 71 210 3.1E-12 T 28-03-2018 A6A12_RS12570 3b5c94eadb64aa20c638900c46977ed6 159 Pfam PF09523 Protein of unknown function (DUF2390) 15 115 4.0E-28 T 28-03-2018 IPR012659 Conserved hypothetical protein CHP02444 A6A12_RS12570 3b5c94eadb64aa20c638900c46977ed6 159 TIGRFAM TIGR02444 TIGR02444: TIGR02444 family protein 13 119 7.4E-36 T 28-03-2018 IPR012659 Conserved hypothetical protein CHP02444 A6A12_RS12210 4b417bed43b2398094aa8e4c147e3a07 330 Gene3D G3DSA:3.40.190.10 168 316 2.7E-12 T 28-03-2018 A6A12_RS12210 4b417bed43b2398094aa8e4c147e3a07 330 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 21 324 3.7E-145 T 28-03-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030288|GO:0030975 A6A12_RS12210 4b417bed43b2398094aa8e4c147e3a07 330 Pfam PF13343 Bacterial extracellular solute-binding protein 76 294 9.7E-20 T 28-03-2018 A6A12_RS12210 4b417bed43b2398094aa8e4c147e3a07 330 Gene3D G3DSA:3.40.190.10 23 167 1.9E-18 T 28-03-2018 A6A12_RS12210 4b417bed43b2398094aa8e4c147e3a07 330 TIGRFAM TIGR01276 thiB: thiamin/thiamin pyrophosphate ABC transporter, thiamin/thiamin pyrophospate-binding protein 16 329 1.8E-147 T 28-03-2018 IPR005967 Thiamin/thiamin pyrophosphate ABC transporter, substrate-binding protein, Proteobacteria GO:0015888|GO:0030288|GO:0030975 A6A12_RS12210 4b417bed43b2398094aa8e4c147e3a07 330 SUPERFAMILY SSF53850 25 325 4.56E-63 T 28-03-2018 A6A12_RS13365 bca948197ef629cc006934558c8951d8 257 Pfam PF00483 Nucleotidyl transferase 2 200 3.8E-18 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A6A12_RS13365 bca948197ef629cc006934558c8951d8 257 Gene3D G3DSA:3.90.550.10 1 257 8.6E-50 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13365 bca948197ef629cc006934558c8951d8 257 SUPERFAMILY SSF53448 1 256 3.34E-68 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13365 bca948197ef629cc006934558c8951d8 257 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 256 8.9E-145 T 28-03-2018 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 A6A12_RS02365 9d97b81bdbb1cb0ec7d8105f5d71cb54 117 SMART SM00905 4 114 4.7E-49 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A6A12_RS02365 9d97b81bdbb1cb0ec7d8105f5d71cb54 117 TIGRFAM TIGR00526 folB_dom: FolB domain 1 115 3.8E-38 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A6A12_RS02365 9d97b81bdbb1cb0ec7d8105f5d71cb54 117 Gene3D G3DSA:3.30.1130.10 1 117 2.3E-36 T 28-03-2018 A6A12_RS02365 9d97b81bdbb1cb0ec7d8105f5d71cb54 117 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 114 8.3E-30 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A6A12_RS02365 9d97b81bdbb1cb0ec7d8105f5d71cb54 117 SUPERFAMILY SSF55620 1 114 2.28E-37 T 28-03-2018 A6A12_RS02365 9d97b81bdbb1cb0ec7d8105f5d71cb54 117 Pfam PF02152 Dihydroneopterin aldolase 4 113 2.9E-32 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 A6A12_RS05135 ce7361881d3a9f60dabe961c5e3d16a9 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 234 3.1E-14 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS05135 ce7361881d3a9f60dabe961c5e3d16a9 242 SMART SM00448 5 116 3.3E-44 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS05135 ce7361881d3a9f60dabe961c5e3d16a9 242 Pfam PF00072 Response regulator receiver domain 7 117 7.7E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS05135 ce7361881d3a9f60dabe961c5e3d16a9 242 Gene3D G3DSA:3.40.50.2300 4 131 5.4E-41 T 28-03-2018 A6A12_RS05135 ce7361881d3a9f60dabe961c5e3d16a9 242 SUPERFAMILY SSF46894 135 235 2.1E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 A6A12_RS05135 ce7361881d3a9f60dabe961c5e3d16a9 242 SUPERFAMILY SSF52172 3 129 3.27E-43 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS05135 ce7361881d3a9f60dabe961c5e3d16a9 242 SMART SM00862 158 234 2.8E-10 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 A6A12_RS05135 ce7361881d3a9f60dabe961c5e3d16a9 242 Gene3D G3DSA:1.10.10.10 132 240 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS11450 75a38ced06f177aa5b26711b72458873 274 SUPERFAMILY SSF53807 22 267 1.06E-57 T 28-03-2018 A6A12_RS11450 75a38ced06f177aa5b26711b72458873 274 Hamap MF_01000 Vitamin B12-binding protein [btuF]. 1 271 48.601 T 28-03-2018 IPR023544 ABC transporter, vitamin B12-binding protein GO:0015889|GO:0031419|GO:0042597 A6A12_RS11450 75a38ced06f177aa5b26711b72458873 274 Pfam PF01497 Periplasmic binding protein 25 246 2.1E-29 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A6A12_RS11450 75a38ced06f177aa5b26711b72458873 274 Gene3D G3DSA:3.40.50.1980 21 126 5.2E-27 T 28-03-2018 A6A12_RS11450 75a38ced06f177aa5b26711b72458873 274 Gene3D G3DSA:3.40.50.1980 127 271 9.0E-26 T 28-03-2018 A6A12_RS14235 58f3e9a271c4010731d7335ef61680bb 254 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 247 8.8E-108 T 28-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A6A12_RS14235 58f3e9a271c4010731d7335ef61680bb 254 Gene3D G3DSA:3.20.20.70 1 254 6.1E-51 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS14235 58f3e9a271c4010731d7335ef61680bb 254 Hamap MF_00443 Thiazole synthase [thiG]. 1 253 42.566 T 28-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A6A12_RS14235 58f3e9a271c4010731d7335ef61680bb 254 SUPERFAMILY SSF110399 1 236 1.44E-83 T 28-03-2018 A6A12_RS03435 9b5207f69c8d58d5e49d7deb50eee344 203 Pfam PF00578 AhpC/TSA family 4 139 9.0E-34 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A6A12_RS03435 9b5207f69c8d58d5e49d7deb50eee344 203 SUPERFAMILY SSF52833 1 196 8.41E-67 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS03435 9b5207f69c8d58d5e49d7deb50eee344 203 Gene3D G3DSA:3.40.30.10 3 161 3.4E-40 T 28-03-2018 A6A12_RS03435 9b5207f69c8d58d5e49d7deb50eee344 203 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 192 1.6E-7 T 28-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A6A12_RS03435 9b5207f69c8d58d5e49d7deb50eee344 203 Gene3D G3DSA:3.30.1020.10 162 199 2.5E-12 T 28-03-2018 A6A12_RS03435 9b5207f69c8d58d5e49d7deb50eee344 203 PIRSF PIRSF000239 1 202 1.1E-59 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A6A12_RS01935 1993eb7dc6f2c418d0b4caf952fc93b2 368 Pfam PF00437 Type II/IV secretion system protein 26 267 2.7E-37 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 A6A12_RS01935 1993eb7dc6f2c418d0b4caf952fc93b2 368 SUPERFAMILY SSF52540 4 334 1.66E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01935 1993eb7dc6f2c418d0b4caf952fc93b2 368 Gene3D G3DSA:3.30.450.90 1 97 2.8E-18 T 28-03-2018 A6A12_RS01935 1993eb7dc6f2c418d0b4caf952fc93b2 368 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 342 7.9E-128 T 28-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 A6A12_RS01935 1993eb7dc6f2c418d0b4caf952fc93b2 368 Gene3D G3DSA:3.40.50.300 113 269 4.1E-27 T 28-03-2018 A6A12_RS01935 1993eb7dc6f2c418d0b4caf952fc93b2 368 Gene3D G3DSA:3.40.50.300 270 345 8.8E-12 T 28-03-2018 A6A12_RS07430 d659a793f6f7be71b130dca342586021 127 Gene3D G3DSA:3.40.50.2300 3 127 9.4E-38 T 28-03-2018 A6A12_RS07430 d659a793f6f7be71b130dca342586021 127 SMART SM00448 8 121 2.2E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS07430 d659a793f6f7be71b130dca342586021 127 SUPERFAMILY SSF52172 8 126 1.71E-37 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS07430 d659a793f6f7be71b130dca342586021 127 Pfam PF00072 Response regulator receiver domain 10 121 1.2E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS13765 0db166930abd49957cc0dcc1fab7ee7f 305 SUPERFAMILY SSF103481 189 291 5.36E-9 T 28-03-2018 A6A12_RS13765 0db166930abd49957cc0dcc1fab7ee7f 305 SUPERFAMILY SSF103481 50 146 1.83E-13 T 28-03-2018 A6A12_RS13765 0db166930abd49957cc0dcc1fab7ee7f 305 Pfam PF00892 EamA-like transporter family 12 145 5.3E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A6A12_RS13765 0db166930abd49957cc0dcc1fab7ee7f 305 TIGRFAM TIGR00688 rarD: protein RarD 11 264 1.9E-84 T 28-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 A6A12_RS00985 db08926b80b250edf4920483ab2ca2b9 328 SUPERFAMILY SSF56935 75 320 1.95E-5 T 28-03-2018 A6A12_RS00985 db08926b80b250edf4920483ab2ca2b9 328 Gene3D G3DSA:2.40.160.10 31 142 0.06 T 28-03-2018 A6A12_RS00985 db08926b80b250edf4920483ab2ca2b9 328 Gene3D G3DSA:2.40.160.10 145 320 3.5E-4 T 28-03-2018 A6A12_RS00985 db08926b80b250edf4920483ab2ca2b9 328 Pfam PF11383 Protein of unknown function (DUF3187) 10 320 2.6E-100 T 28-03-2018 IPR021523 Protein of unknown function DUF3187 A6A12_RS06550 62eea7eb231c5630f47d38e66128fee8 159 SUPERFAMILY SSF54637 12 156 1.12E-14 T 28-03-2018 IPR029069 HotDog domain A6A12_RS06550 62eea7eb231c5630f47d38e66128fee8 159 Gene3D G3DSA:3.10.129.10 4 157 1.6E-12 T 28-03-2018 A6A12_RS06550 62eea7eb231c5630f47d38e66128fee8 159 Pfam PF14539 Domain of unknown function (DUF4442) 18 110 4.3E-9 T 28-03-2018 IPR027961 Protein of unknown function DUF4442 A6A12_RS10965 612b8820403838a9789b144ad396832d 149 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 149 89.429 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A6A12_RS10965 612b8820403838a9789b144ad396832d 149 Pfam PF03477 ATP cone domain 50 136 6.0E-16 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A6A12_RS10965 612b8820403838a9789b144ad396832d 149 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 7.3E-73 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 A6A12_RS01205 899e57ba20bf35783cc86914c447dfdd 355 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 9 347 6.6E-139 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A6A12_RS01205 899e57ba20bf35783cc86914c447dfdd 355 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 350 50.28 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A6A12_RS01205 899e57ba20bf35783cc86914c447dfdd 355 Gene3D G3DSA:3.20.20.210 1 355 7.4E-110 T 28-03-2018 A6A12_RS01205 899e57ba20bf35783cc86914c447dfdd 355 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 142 158 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A6A12_RS01205 899e57ba20bf35783cc86914c447dfdd 355 SUPERFAMILY SSF51726 1 354 1.7E-120 T 28-03-2018 A6A12_RS01205 899e57ba20bf35783cc86914c447dfdd 355 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 22 31 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A6A12_RS01205 899e57ba20bf35783cc86914c447dfdd 355 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 5 348 3.0E-140 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 A6A12_RS03625 c7ff379aba4ddff518816010ac3ee375 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 65 6.9E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS03625 c7ff379aba4ddff518816010ac3ee375 296 Gene3D G3DSA:3.40.190.10 174 270 2.6E-16 T 28-03-2018 A6A12_RS03625 c7ff379aba4ddff518816010ac3ee375 296 Gene3D G3DSA:3.40.190.10 92 173 9.6E-17 T 28-03-2018 A6A12_RS03625 c7ff379aba4ddff518816010ac3ee375 296 SUPERFAMILY SSF53850 93 295 2.17E-26 T 28-03-2018 A6A12_RS03625 c7ff379aba4ddff518816010ac3ee375 296 SUPERFAMILY SSF46785 6 88 1.09E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03625 c7ff379aba4ddff518816010ac3ee375 296 Gene3D G3DSA:1.10.10.10 2 89 3.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03625 c7ff379aba4ddff518816010ac3ee375 296 Pfam PF03466 LysR substrate binding domain 93 294 3.6E-25 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS03625 c7ff379aba4ddff518816010ac3ee375 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS03625 c7ff379aba4ddff518816010ac3ee375 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS03625 c7ff379aba4ddff518816010ac3ee375 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.7E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS07830 c6e485e7422223e897d31065be651741 176 Pfam PF05638 Type VI secretion system effector, Hcp 5 148 8.5E-27 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp A6A12_RS07830 c6e485e7422223e897d31065be651741 176 Gene3D G3DSA:2.30.110.20 1 169 8.3E-35 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp A6A12_RS07830 c6e485e7422223e897d31065be651741 176 SUPERFAMILY SSF141452 1 171 2.35E-30 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp A6A12_RS00160 a038b1c07c45ed4a1176105d268bb169 596 SUPERFAMILY SSF69572 348 509 1.09E-17 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A6A12_RS00160 a038b1c07c45ed4a1176105d268bb169 596 Gene3D G3DSA:3.40.50.720 340 557 4.5E-18 T 28-03-2018 A6A12_RS00160 a038b1c07c45ed4a1176105d268bb169 596 Pfam PF00899 ThiF family 336 462 7.0E-17 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A6A12_RS03470 792584b24aa259d58df4779c6e7678b7 110 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 22 102 4.8E-29 T 28-03-2018 IPR003849 Preprotein translocase YajC A6A12_RS03470 792584b24aa259d58df4779c6e7678b7 110 SMART SM01323 18 102 6.1E-37 T 28-03-2018 IPR003849 Preprotein translocase YajC A6A12_RS03470 792584b24aa259d58df4779c6e7678b7 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 58 76 1.5E-15 T 28-03-2018 IPR003849 Preprotein translocase YajC A6A12_RS03470 792584b24aa259d58df4779c6e7678b7 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 20 40 1.5E-15 T 28-03-2018 IPR003849 Preprotein translocase YajC A6A12_RS03470 792584b24aa259d58df4779c6e7678b7 110 Pfam PF02699 Preprotein translocase subunit 22 99 1.5E-25 T 28-03-2018 IPR003849 Preprotein translocase YajC A6A12_RS02935 87abc1e95736eb122d2e9c93eb50b209 276 SUPERFAMILY SSF51717 3 274 3.66E-106 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS02935 87abc1e95736eb122d2e9c93eb50b209 276 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 51 64 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS02935 87abc1e95736eb122d2e9c93eb50b209 276 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 17 271 1.1E-102 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 A6A12_RS02935 87abc1e95736eb122d2e9c93eb50b209 276 Gene3D G3DSA:3.20.20.20 2 276 4.2E-110 T 28-03-2018 A6A12_RS02935 87abc1e95736eb122d2e9c93eb50b209 276 Pfam PF00809 Pterin binding enzyme 18 257 6.1E-90 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS02935 87abc1e95736eb122d2e9c93eb50b209 276 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 17 32 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A6A12_RS11515 52f5fda5036951916f3607400cd5780b 257 Pfam PF03799 Cell division protein FtsQ 124 236 1.3E-23 T 28-03-2018 IPR005548 Cell division protein FtsQ/DivIB A6A12_RS11515 52f5fda5036951916f3607400cd5780b 257 Pfam PF08478 POTRA domain, FtsQ-type 51 120 3.6E-16 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type A6A12_RS11515 52f5fda5036951916f3607400cd5780b 257 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 20 244 21.137 T 28-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 A6A12_RS00280 845836d794448bb42eccc64d929151c0 158 Pfam PF04361 Protein of unknown function (DUF494) 2 158 2.8E-59 T 28-03-2018 IPR007456 Smg A6A12_RS00280 845836d794448bb42eccc64d929151c0 158 Hamap MF_00598 Protein Smg [smg]. 2 158 32.713 T 28-03-2018 IPR007456 Smg A6A12_RS13450 d0a76300c282f3b97dcf5a376e7a141a 422 Gene3D G3DSA:3.40.50.2000 231 420 3.1E-12 T 28-03-2018 A6A12_RS13450 d0a76300c282f3b97dcf5a376e7a141a 422 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 35 212 4.7E-63 T 28-03-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 A6A12_RS13450 d0a76300c282f3b97dcf5a376e7a141a 422 Gene3D G3DSA:3.20.20.20 56 230 1.5E-4 T 28-03-2018 A6A12_RS13450 d0a76300c282f3b97dcf5a376e7a141a 422 SUPERFAMILY SSF53756 55 406 2.2E-15 T 28-03-2018 A6A12_RS08435 3878945c4a304e0000f1793aec6be929 395 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 7 391 1.9E-60 T 28-03-2018 IPR024455 Phage capsid A6A12_RS08435 3878945c4a304e0000f1793aec6be929 395 SUPERFAMILY SSF56563 116 393 4.32E-78 T 28-03-2018 A6A12_RS08435 3878945c4a304e0000f1793aec6be929 395 Gene3D G3DSA:3.30.2400.10 142 288 9.7E-29 T 28-03-2018 A6A12_RS08435 3878945c4a304e0000f1793aec6be929 395 Gene3D G3DSA:3.30.2400.10 299 382 1.2E-7 T 28-03-2018 A6A12_RS08435 3878945c4a304e0000f1793aec6be929 395 Pfam PF05065 Phage capsid family 121 390 4.0E-57 T 28-03-2018 IPR024455 Phage capsid A6A12_RS09345 9e28bd396007eda1638ff4ec44085249 591 Pfam PF13175 AAA ATPase domain 15 364 7.3E-20 T 28-03-2018 A6A12_RS09345 9e28bd396007eda1638ff4ec44085249 591 SUPERFAMILY SSF52540 15 367 2.06E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09345 9e28bd396007eda1638ff4ec44085249 591 Gene3D G3DSA:3.40.50.300 14 407 2.7E-18 T 28-03-2018 A6A12_RS05995 a9963fbf816b053638c880dd828f4e64 215 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS05995 a9963fbf816b053638c880dd828f4e64 215 Gene3D G3DSA:3.40.50.300 1 207 4.8E-50 T 28-03-2018 A6A12_RS05995 a9963fbf816b053638c880dd828f4e64 215 SMART SM00382 28 212 4.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS05995 a9963fbf816b053638c880dd828f4e64 215 SUPERFAMILY SSF52540 9 199 1.19E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05995 a9963fbf816b053638c880dd828f4e64 215 Pfam PF00005 ABC transporter 19 163 7.7E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS09985 a687057f8442754cbebed0453c829c52 260 Gene3D G3DSA:3.40.50.300 1 242 2.5E-53 T 28-03-2018 A6A12_RS09985 a687057f8442754cbebed0453c829c52 260 SMART SM00382 29 199 1.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS09985 a687057f8442754cbebed0453c829c52 260 SUPERFAMILY SSF52540 3 222 1.96E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09985 a687057f8442754cbebed0453c829c52 260 Pfam PF00005 ABC transporter 20 148 1.4E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS06350 c726f8666c05d987d38d41bbefd6e822 335 Gene3D G3DSA:1.10.3470.10 34 330 1.4E-31 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A6A12_RS06350 c726f8666c05d987d38d41bbefd6e822 335 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 324 9.1E-49 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A6A12_RS13510 764d303ed2c72fdfd167716a073ea109 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS13510 764d303ed2c72fdfd167716a073ea109 55 SUPERFAMILY SSF57829 1 53 1.04E-18 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A6A12_RS13510 764d303ed2c72fdfd167716a073ea109 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 5.3E-25 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS13510 764d303ed2c72fdfd167716a073ea109 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 14.441 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS13510 764d303ed2c72fdfd167716a073ea109 55 Pfam PF00471 Ribosomal protein L33 7 53 4.0E-16 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS10855 4c4a7d600b5708d6c66239e671af2ced 150 SUPERFAMILY SSF54637 7 146 4.79E-49 T 28-03-2018 IPR029069 HotDog domain A6A12_RS10855 4c4a7d600b5708d6c66239e671af2ced 150 Pfam PF07977 FabA-like domain 17 141 1.3E-39 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A6A12_RS10855 4c4a7d600b5708d6c66239e671af2ced 150 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 8 149 36.511 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A6A12_RS10855 4c4a7d600b5708d6c66239e671af2ced 150 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 8 146 3.5E-59 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 A6A12_RS10855 4c4a7d600b5708d6c66239e671af2ced 150 Gene3D G3DSA:3.10.129.10 1 149 3.8E-52 T 28-03-2018 A6A12_RS11325 de3094abde1f6580222c4b2142791cee 262 PIRSF PIRSF005902 2 261 1.9E-70 T 28-03-2018 IPR001130 TatD family GO:0016788 A6A12_RS11325 de3094abde1f6580222c4b2142791cee 262 Pfam PF01026 TatD related DNase 10 259 4.5E-66 T 28-03-2018 IPR001130 TatD family GO:0016788 A6A12_RS11325 de3094abde1f6580222c4b2142791cee 262 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 9 259 6.4E-62 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A6A12_RS11325 de3094abde1f6580222c4b2142791cee 262 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 9 17 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A6A12_RS11325 de3094abde1f6580222c4b2142791cee 262 SUPERFAMILY SSF51556 9 260 5.68E-76 T 28-03-2018 IPR032466 Metal-dependent hydrolase A6A12_RS11325 de3094abde1f6580222c4b2142791cee 262 Gene3D G3DSA:3.20.20.140 7 261 4.4E-75 T 28-03-2018 A6A12_RS11325 de3094abde1f6580222c4b2142791cee 262 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 196 212 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A6A12_RS12495 3412f7c8f85d290945104b2a0c3cd676 100 ProSitePatterns PS00050 Ribosomal protein L23 signature. 81 96 - T 28-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12495 3412f7c8f85d290945104b2a0c3cd676 100 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 8 98 22.479 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A6A12_RS12495 3412f7c8f85d290945104b2a0c3cd676 100 SUPERFAMILY SSF54189 6 97 2.34E-32 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS12495 3412f7c8f85d290945104b2a0c3cd676 100 Gene3D G3DSA:3.30.70.330 6 100 7.9E-33 T 28-03-2018 A6A12_RS12495 3412f7c8f85d290945104b2a0c3cd676 100 Pfam PF00276 Ribosomal protein L23 9 95 2.4E-31 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A6A12_RS13950 11d6c4f5e3f7941f6244a6e4a85c83f7 518 SUPERFAMILY SSF53850 25 514 5.61E-127 T 28-03-2018 A6A12_RS13950 11d6c4f5e3f7941f6244a6e4a85c83f7 518 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 67 425 2.4E-83 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain A6A12_RS13950 11d6c4f5e3f7941f6244a6e4a85c83f7 518 Gene3D G3DSA:3.10.105.10 282 488 3.3E-51 T 28-03-2018 A6A12_RS13950 11d6c4f5e3f7941f6244a6e4a85c83f7 518 Gene3D G3DSA:3.90.76.10 33 176 1.1E-33 T 28-03-2018 A6A12_RS13950 11d6c4f5e3f7941f6244a6e4a85c83f7 518 Gene3D G3DSA:3.40.190.10 179 281 3.7E-24 T 28-03-2018 A6A12_RS13950 11d6c4f5e3f7941f6244a6e4a85c83f7 518 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 72 93 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site A6A12_RS13950 11d6c4f5e3f7941f6244a6e4a85c83f7 518 PIRSF PIRSF002741 18 502 1.1E-94 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A6A12_RS07770 42bd838f0fca9c7f3c0d2c1dc38aaaf9 315 Gene3D G3DSA:2.60.200.20 14 135 2.5E-15 T 28-03-2018 A6A12_RS07770 42bd838f0fca9c7f3c0d2c1dc38aaaf9 315 Pfam PF00498 FHA domain 29 97 3.4E-12 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A6A12_RS07770 42bd838f0fca9c7f3c0d2c1dc38aaaf9 315 SUPERFAMILY SSF49879 16 114 1.26E-17 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 A6A12_RS07770 42bd838f0fca9c7f3c0d2c1dc38aaaf9 315 SMART SM00240 27 78 0.0027 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 A6A12_RS06950 80ecd40001a5125a79f402d793ff81f9 503 PIRSF PIRSF036685 4 503 2.4E-246 T 28-03-2018 IPR012189 Peptidase M28E, aminopeptidase AP1 A6A12_RS06950 80ecd40001a5125a79f402d793ff81f9 503 SUPERFAMILY SSF53187 110 395 1.37E-68 T 28-03-2018 A6A12_RS06950 80ecd40001a5125a79f402d793ff81f9 503 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 422 485 2.6E-13 T 28-03-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial A6A12_RS06950 80ecd40001a5125a79f402d793ff81f9 503 Gene3D G3DSA:3.40.630.10 107 404 5.2E-53 T 28-03-2018 A6A12_RS06950 80ecd40001a5125a79f402d793ff81f9 503 Pfam PF04389 Peptidase family M28 184 381 7.3E-38 T 28-03-2018 IPR007484 Peptidase M28 A6A12_RS06950 80ecd40001a5125a79f402d793ff81f9 503 SUPERFAMILY SSF89260 394 498 2.62E-11 T 28-03-2018 A6A12_RS06950 80ecd40001a5125a79f402d793ff81f9 503 Gene3D G3DSA:2.60.120.380 407 503 9.6E-15 T 28-03-2018 A6A12_RS01235 2a3ffd330ddd4c959cfcfc63307a1487 626 Gene3D G3DSA:3.30.450.20 24 155 1.1E-20 T 28-03-2018 A6A12_RS01235 2a3ffd330ddd4c959cfcfc63307a1487 626 Pfam PF02743 Cache domain 40 257 2.7E-27 T 28-03-2018 IPR033479 Double Cache domain 1 A6A12_RS01235 2a3ffd330ddd4c959cfcfc63307a1487 626 SMART SM00304 295 349 2.2E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS01235 2a3ffd330ddd4c959cfcfc63307a1487 626 SMART SM00304 384 451 45.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS01235 2a3ffd330ddd4c959cfcfc63307a1487 626 Gene3D G3DSA:3.30.450.20 156 272 2.6E-18 T 28-03-2018 A6A12_RS01235 2a3ffd330ddd4c959cfcfc63307a1487 626 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 434 590 3.0E-40 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS01235 2a3ffd330ddd4c959cfcfc63307a1487 626 SMART SM00283 364 625 5.6E-69 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS01235 2a3ffd330ddd4c959cfcfc63307a1487 626 SUPERFAMILY SSF58104 317 626 4.32E-76 T 28-03-2018 A6A12_RS01235 2a3ffd330ddd4c959cfcfc63307a1487 626 SUPERFAMILY SSF103190 70 175 3.14E-10 T 28-03-2018 IPR029151 Periplasmic sensor domain-like A6A12_RS01235 2a3ffd330ddd4c959cfcfc63307a1487 626 Pfam PF00672 HAMP domain 296 345 2.2E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS01235 2a3ffd330ddd4c959cfcfc63307a1487 626 Gene3D G3DSA:1.10.287.950 293 397 8.3E-7 T 28-03-2018 A6A12_RS01235 2a3ffd330ddd4c959cfcfc63307a1487 626 Gene3D G3DSA:1.10.287.950 398 626 9.1E-53 T 28-03-2018 A6A12_RS13915 e2890cf76f02545ca13b50b51fa9074a 505 Gene3D G3DSA:3.40.140.10 237 447 9.7E-35 T 28-03-2018 A6A12_RS13915 e2890cf76f02545ca13b50b51fa9074a 505 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 356 391 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A6A12_RS13915 e2890cf76f02545ca13b50b51fa9074a 505 SUPERFAMILY SSF53927 346 454 2.86E-32 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A6A12_RS13915 e2890cf76f02545ca13b50b51fa9074a 505 SUPERFAMILY SSF53927 232 275 2.86E-32 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 A6A12_RS13915 e2890cf76f02545ca13b50b51fa9074a 505 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 238 402 5.8E-21 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A6A12_RS06790 7db6eb76dad8d54c3fbbd67f4b26ce8e 245 Pfam PF02146 Sir2 family 13 186 2.0E-50 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 A6A12_RS06790 7db6eb76dad8d54c3fbbd67f4b26ce8e 245 SUPERFAMILY SSF52467 6 234 1.89E-72 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A6A12_RS06790 7db6eb76dad8d54c3fbbd67f4b26ce8e 245 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 6 236 55.273 T 28-03-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 A6A12_RS06790 7db6eb76dad8d54c3fbbd67f4b26ce8e 245 Gene3D G3DSA:3.40.50.1220 4 244 1.0E-50 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain A6A12_RS13135 bd5966b3f17d9c066563f4c5771fe87f 431 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 332 421 2.2E-29 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A6A12_RS13135 bd5966b3f17d9c066563f4c5771fe87f 431 Gene3D G3DSA:3.30.470.20 191 329 1.9E-63 T 28-03-2018 A6A12_RS13135 bd5966b3f17d9c066563f4c5771fe87f 431 SMART SM01209 103 296 9.2E-141 T 28-03-2018 A6A12_RS13135 bd5966b3f17d9c066563f4c5771fe87f 431 Gene3D G3DSA:3.40.50.20 2 95 2.2E-37 T 28-03-2018 A6A12_RS13135 bd5966b3f17d9c066563f4c5771fe87f 431 SUPERFAMILY SSF56059 104 323 9.37E-68 T 28-03-2018 A6A12_RS13135 bd5966b3f17d9c066563f4c5771fe87f 431 Gene3D G3DSA:3.90.600.10 330 423 1.7E-34 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A6A12_RS13135 bd5966b3f17d9c066563f4c5771fe87f 431 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 423 2.3E-183 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A6A12_RS13135 bd5966b3f17d9c066563f4c5771fe87f 431 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 102 8.1E-35 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A6A12_RS13135 bd5966b3f17d9c066563f4c5771fe87f 431 SMART SM01210 330 423 4.0E-54 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A6A12_RS13135 bd5966b3f17d9c066563f4c5771fe87f 431 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 296 5.3E-81 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A6A12_RS13135 bd5966b3f17d9c066563f4c5771fe87f 431 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A6A12_RS13135 bd5966b3f17d9c066563f4c5771fe87f 431 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 423 43.42 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A6A12_RS13135 bd5966b3f17d9c066563f4c5771fe87f 431 SUPERFAMILY SSF51246 329 424 1.88E-32 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A6A12_RS13135 bd5966b3f17d9c066563f4c5771fe87f 431 Gene3D G3DSA:3.30.1490.20 135 189 1.1E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A6A12_RS13135 bd5966b3f17d9c066563f4c5771fe87f 431 SUPERFAMILY SSF52440 1 103 7.63E-36 T 28-03-2018 IPR016185 Pre-ATP-grasp domain A6A12_RS13155 5a14da558162d85760b94d76694e2d76 118 Pfam PF04480 Protein of unknown function (DUF559) 8 114 9.6E-31 T 28-03-2018 IPR007569 Domain of unknown function DUF559 A6A12_RS13155 5a14da558162d85760b94d76694e2d76 118 Gene3D G3DSA:3.40.960.10 19 117 5.2E-24 T 28-03-2018 A6A12_RS13155 5a14da558162d85760b94d76694e2d76 118 SUPERFAMILY SSF52980 4 115 1.61E-17 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A6A12_RS13440 388f52b0749b59689c689770e77efef8 346 Gene3D G3DSA:3.40.50.2000 23 181 4.4E-19 T 28-03-2018 A6A12_RS13440 388f52b0749b59689c689770e77efef8 346 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 106 329 3.4E-15 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 A6A12_RS13440 388f52b0749b59689c689770e77efef8 346 Gene3D G3DSA:3.40.50.2000 187 345 9.0E-18 T 28-03-2018 A6A12_RS13440 388f52b0749b59689c689770e77efef8 346 SUPERFAMILY SSF53756 31 323 1.81E-40 T 28-03-2018 A6A12_RS05415 5065b0e3f4ca4f2c6deae5b84a5d5156 332 SUPERFAMILY SSF52418 70 329 4.19E-93 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS05415 5065b0e3f4ca4f2c6deae5b84a5d5156 332 Gene3D G3DSA:1.20.970.10 3 67 1.6E-16 T 28-03-2018 A6A12_RS05415 5065b0e3f4ca4f2c6deae5b84a5d5156 332 Gene3D G3DSA:3.40.1030.10 68 331 5.4E-94 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS05415 5065b0e3f4ca4f2c6deae5b84a5d5156 332 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 63 2.4E-15 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS05415 5065b0e3f4ca4f2c6deae5b84a5d5156 332 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 3 331 39.478 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A6A12_RS05415 5065b0e3f4ca4f2c6deae5b84a5d5156 332 Pfam PF00591 Glycosyl transferase family, a/b domain 72 322 4.8E-102 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS05415 5065b0e3f4ca4f2c6deae5b84a5d5156 332 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 5 330 2.4E-126 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 A6A12_RS05415 5065b0e3f4ca4f2c6deae5b84a5d5156 332 SUPERFAMILY SSF47648 1 67 1.57E-18 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A6A12_RS09370 f67acf166452c61162e7838a4d22f39b 603 SUPERFAMILY SSF143975 5 419 1.02E-126 T 28-03-2018 A6A12_RS09370 f67acf166452c61162e7838a4d22f39b 603 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 507 518 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A6A12_RS09370 f67acf166452c61162e7838a4d22f39b 603 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 7 599 7.4E-246 T 28-03-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 A6A12_RS09370 f67acf166452c61162e7838a4d22f39b 603 SUPERFAMILY SSF52016 421 600 1.26E-52 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A6A12_RS09370 f67acf166452c61162e7838a4d22f39b 603 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 158 168 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A6A12_RS09370 f67acf166452c61162e7838a4d22f39b 603 Pfam PF00920 Dehydratase family 70 597 7.4E-145 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 A6A12_RS00285 254bd813b64baeb21195cb81781c794b 193 SUPERFAMILY SSF57783 69 103 1.87E-12 T 28-03-2018 A6A12_RS00285 254bd813b64baeb21195cb81781c794b 193 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 70 102 2.2E-15 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A6A12_RS00285 254bd813b64baeb21195cb81781c794b 193 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 116 153 6.3E-14 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A6A12_RS00285 254bd813b64baeb21195cb81781c794b 193 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 24 60 2.3E-16 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A6A12_RS00285 254bd813b64baeb21195cb81781c794b 193 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 157 173 0.37 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A6A12_RS00285 254bd813b64baeb21195cb81781c794b 193 SUPERFAMILY SSF57783 20 67 4.25E-14 T 28-03-2018 A6A12_RS00285 254bd813b64baeb21195cb81781c794b 193 Gene3D G3DSA:3.30.65.10 153 193 0.066 T 28-03-2018 A6A12_RS00285 254bd813b64baeb21195cb81781c794b 193 Gene3D G3DSA:3.30.65.10 65 105 5.7E-16 T 28-03-2018 A6A12_RS00285 254bd813b64baeb21195cb81781c794b 193 Gene3D G3DSA:3.30.65.10 7 64 1.7E-16 T 28-03-2018 A6A12_RS00285 254bd813b64baeb21195cb81781c794b 193 Gene3D G3DSA:3.30.65.10 106 152 4.4E-11 T 28-03-2018 A6A12_RS01610 a05ea3db4563bb9c6e7af8e99d961a9a 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 368 382 1.1E-8 T 28-03-2018 IPR003004 GspF/PilC family A6A12_RS01610 a05ea3db4563bb9c6e7af8e99d961a9a 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 66 78 1.1E-8 T 28-03-2018 IPR003004 GspF/PilC family A6A12_RS01610 a05ea3db4563bb9c6e7af8e99d961a9a 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 165 193 1.1E-8 T 28-03-2018 IPR003004 GspF/PilC family A6A12_RS01610 a05ea3db4563bb9c6e7af8e99d961a9a 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 384 403 1.1E-8 T 28-03-2018 IPR003004 GspF/PilC family A6A12_RS01610 a05ea3db4563bb9c6e7af8e99d961a9a 405 Gene3D G3DSA:3.30.70.1120 93 169 1.7E-4 T 28-03-2018 A6A12_RS01610 a05ea3db4563bb9c6e7af8e99d961a9a 405 Gene3D G3DSA:3.30.70.1120 303 373 7.2E-4 T 28-03-2018 A6A12_RS01610 a05ea3db4563bb9c6e7af8e99d961a9a 405 Pfam PF00482 Type II secretion system (T2SS), protein F 273 395 1.4E-26 T 28-03-2018 IPR018076 Type II secretion system F domain A6A12_RS01610 a05ea3db4563bb9c6e7af8e99d961a9a 405 Pfam PF00482 Type II secretion system (T2SS), protein F 70 193 7.0E-30 T 28-03-2018 IPR018076 Type II secretion system F domain A6A12_RS07185 4c207f9a31830f0aadd64bbb73566fc0 176 Pfam PF00929 Exonuclease 7 171 2.8E-13 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS07185 4c207f9a31830f0aadd64bbb73566fc0 176 SMART SM00479 5 176 1.0E-4 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS07185 4c207f9a31830f0aadd64bbb73566fc0 176 SUPERFAMILY SSF53098 3 175 6.83E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS07185 4c207f9a31830f0aadd64bbb73566fc0 176 Gene3D G3DSA:3.30.420.10 1 176 9.9E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS09540 2c1b0c9c38354730e3c1353eaadc6623 332 TIGRFAM TIGR01927 menC_gamma/gm+: o-succinylbenzoate synthase 7 313 2.9E-113 T 28-03-2018 A6A12_RS09540 2c1b0c9c38354730e3c1353eaadc6623 332 Gene3D G3DSA:3.30.390.10 1 111 6.3E-14 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS09540 2c1b0c9c38354730e3c1353eaadc6623 332 SUPERFAMILY SSF51604 105 308 7.86E-47 T 28-03-2018 IPR029065 Enolase C-terminal domain-like A6A12_RS09540 2c1b0c9c38354730e3c1353eaadc6623 332 Pfam PF13378 Enolase C-terminal domain-like 130 285 3.0E-13 T 28-03-2018 IPR029065 Enolase C-terminal domain-like A6A12_RS09540 2c1b0c9c38354730e3c1353eaadc6623 332 Gene3D G3DSA:3.20.20.120 112 301 2.3E-32 T 28-03-2018 IPR029065 Enolase C-terminal domain-like A6A12_RS09540 2c1b0c9c38354730e3c1353eaadc6623 332 SUPERFAMILY SSF54826 1 100 1.62E-24 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS09540 2c1b0c9c38354730e3c1353eaadc6623 332 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 4 321 23.383 T 28-03-2018 IPR010196 o-Succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A6A12_RS09540 2c1b0c9c38354730e3c1353eaadc6623 332 SMART SM00922 116 212 1.1E-8 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal A6A12_RS09700 eca58b366cf189f23fba4d458802f066 341 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 340 133.167 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 A6A12_RS09700 eca58b366cf189f23fba4d458802f066 341 PIRSF PIRSF002465 2 339 6.1E-120 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 A6A12_RS09700 eca58b366cf189f23fba4d458802f066 341 Pfam PF02504 Fatty acid synthesis protein 5 327 7.7E-99 T 28-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 A6A12_RS09700 eca58b366cf189f23fba4d458802f066 341 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 6 335 5.5E-104 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 A6A12_RS09700 eca58b366cf189f23fba4d458802f066 341 Gene3D G3DSA:3.40.718.10 1 337 3.0E-98 T 28-03-2018 A6A12_RS09700 eca58b366cf189f23fba4d458802f066 341 SUPERFAMILY SSF53659 4 336 6.58E-99 T 28-03-2018 A6A12_RS05815 7c1a62af11be3dc0212a7526e03a530f 323 TIGRFAM TIGR00452 TIGR00452: tRNA (mo5U34)-methyltransferase 12 321 1.0E-147 T 28-03-2018 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 A6A12_RS05815 7c1a62af11be3dc0212a7526e03a530f 323 SUPERFAMILY SSF53335 91 321 1.51E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS05815 7c1a62af11be3dc0212a7526e03a530f 323 Gene3D G3DSA:3.40.50.150 80 308 1.1E-22 T 28-03-2018 A6A12_RS05815 7c1a62af11be3dc0212a7526e03a530f 323 Pfam PF08003 Protein of unknown function (DUF1698) 7 322 3.4E-172 T 28-03-2018 IPR027555 tRNA (mo5U34)-methyltransferase-like A6A12_RS05815 7c1a62af11be3dc0212a7526e03a530f 323 Hamap MF_01590 tRNA U34 carboxymethyltransferase [cmoB]. 13 322 54.434 T 28-03-2018 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 A6A12_RS06820 e2887487b6d5c10a0a133ccf4187a353 344 SUPERFAMILY SSF53850 26 326 2.67E-66 T 28-03-2018 A6A12_RS06820 e2887487b6d5c10a0a133ccf4187a353 344 Gene3D G3DSA:3.40.190.10 26 145 1.3E-7 T 28-03-2018 A6A12_RS06820 e2887487b6d5c10a0a133ccf4187a353 344 Pfam PF13343 Bacterial extracellular solute-binding protein 90 319 2.4E-31 T 28-03-2018 A6A12_RS06820 e2887487b6d5c10a0a133ccf4187a353 344 Gene3D G3DSA:3.40.190.10 146 295 6.1E-34 T 28-03-2018 A6A12_RS06820 e2887487b6d5c10a0a133ccf4187a353 344 PIRSF PIRSF002825 7 340 7.7E-66 T 28-03-2018 IPR026045 Ferric binding protein A6A12_RS03795 7a58278776c98d95bb355154dfc858ae 147 Pfam PF10980 Protein of unknown function (DUF2787) 15 145 7.6E-52 T 28-03-2018 IPR021248 Protein of unknown function DUF2787 A6A12_RS10045 a4da491ef6142ec61dcaa77d928df522 252 Pfam PF08907 Domain of unknown function (DUF1853) 45 217 3.6E-37 T 28-03-2018 IPR015003 Protein of unknown function DUF1853 A6A12_RS06910 eb82a6d9c04a74b141ce372fa1b1bf0f 206 Gene3D G3DSA:3.30.1150.10 28 206 5.3E-21 T 28-03-2018 A6A12_RS06910 eb82a6d9c04a74b141ce372fa1b1bf0f 206 SUPERFAMILY SSF74653 118 196 3.66E-25 T 28-03-2018 A6A12_RS06910 eb82a6d9c04a74b141ce372fa1b1bf0f 206 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 127 204 6.8E-20 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 A6A12_RS06910 eb82a6d9c04a74b141ce372fa1b1bf0f 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 62 72 2.0E-16 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 A6A12_RS06910 eb82a6d9c04a74b141ce372fa1b1bf0f 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 121 142 2.0E-16 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 A6A12_RS06910 eb82a6d9c04a74b141ce372fa1b1bf0f 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 142 160 2.0E-16 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 A6A12_RS06910 eb82a6d9c04a74b141ce372fa1b1bf0f 206 PRINTS PR01374 Gram-negative bacterial tonB protein signature 161 178 2.0E-16 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 A6A12_RS06910 eb82a6d9c04a74b141ce372fa1b1bf0f 206 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 126 204 1.3E-20 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 A6A12_RS13325 8b42971131fdc9fcd383420ce8a2c82f 448 Pfam PF04577 Protein of unknown function (DUF563) 191 414 6.1E-44 T 28-03-2018 IPR007657 Glycosyltransferase 61 GO:0016757 A6A12_RS11690 c797f57a3d474fc8fee1589d85ebbb90 435 SUPERFAMILY SSF56954 1 423 7.72E-92 T 28-03-2018 A6A12_RS11690 c797f57a3d474fc8fee1589d85ebbb90 435 Pfam PF02321 Outer membrane efflux protein 231 417 5.1E-33 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A6A12_RS11690 c797f57a3d474fc8fee1589d85ebbb90 435 Pfam PF02321 Outer membrane efflux protein 26 207 3.1E-27 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A6A12_RS11690 c797f57a3d474fc8fee1589d85ebbb90 435 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 22 431 2.8E-110 T 28-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 A6A12_RS11690 c797f57a3d474fc8fee1589d85ebbb90 435 Gene3D G3DSA:1.20.1600.10 10 426 2.4E-77 T 28-03-2018 A6A12_RS14405 b74775c60889e4bb9ca3b7a3ee34da45 632 SUPERFAMILY SSF51905 97 261 8.15E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS14405 b74775c60889e4bb9ca3b7a3ee34da45 632 SUPERFAMILY SSF51905 5 66 8.15E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS14405 b74775c60889e4bb9ca3b7a3ee34da45 632 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 A6A12_RS14405 b74775c60889e4bb9ca3b7a3ee34da45 632 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 624 42.368 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 A6A12_RS14405 b74775c60889e4bb9ca3b7a3ee34da45 632 SMART SM01228 546 617 1.3E-41 T 28-03-2018 A6A12_RS14405 b74775c60889e4bb9ca3b7a3ee34da45 632 Pfam PF01134 Glucose inhibited division protein A 8 399 1.2E-168 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 A6A12_RS14405 b74775c60889e4bb9ca3b7a3ee34da45 632 Gene3D G3DSA:3.50.50.60 5 264 3.0E-77 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS14405 b74775c60889e4bb9ca3b7a3ee34da45 632 Pfam PF13932 GidA associated domain 403 616 2.9E-75 T 28-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 A6A12_RS14405 b74775c60889e4bb9ca3b7a3ee34da45 632 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 A6A12_RS14405 b74775c60889e4bb9ca3b7a3ee34da45 632 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 622 2.6E-292 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 A6A12_RS13005 ea6816cb9b0f6f8d28b68012413135d3 407 TIGRFAM TIGR01078 arcA: arginine deiminase 4 407 4.4E-160 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS13005 ea6816cb9b0f6f8d28b68012413135d3 407 Gene3D G3DSA:3.75.10.10 3 405 1.4E-97 T 28-03-2018 A6A12_RS13005 ea6816cb9b0f6f8d28b68012413135d3 407 PRINTS PR01466 Bacterial arginine deiminase signature 363 377 8.0E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS13005 ea6816cb9b0f6f8d28b68012413135d3 407 PRINTS PR01466 Bacterial arginine deiminase signature 343 360 8.0E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS13005 ea6816cb9b0f6f8d28b68012413135d3 407 PRINTS PR01466 Bacterial arginine deiminase signature 177 192 8.0E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS13005 ea6816cb9b0f6f8d28b68012413135d3 407 PRINTS PR01466 Bacterial arginine deiminase signature 386 404 8.0E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS13005 ea6816cb9b0f6f8d28b68012413135d3 407 PRINTS PR01466 Bacterial arginine deiminase signature 2 22 8.0E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS13005 ea6816cb9b0f6f8d28b68012413135d3 407 PRINTS PR01466 Bacterial arginine deiminase signature 149 167 8.0E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS13005 ea6816cb9b0f6f8d28b68012413135d3 407 Pfam PF02274 Amidinotransferase 18 404 2.1E-108 T 28-03-2018 A6A12_RS13005 ea6816cb9b0f6f8d28b68012413135d3 407 Hamap MF_00242 Arginine deiminase [arcA]. 1 407 43.368 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS13005 ea6816cb9b0f6f8d28b68012413135d3 407 SUPERFAMILY SSF55909 3 407 3.53E-126 T 28-03-2018 A6A12_RS13005 ea6816cb9b0f6f8d28b68012413135d3 407 PIRSF PIRSF006356 1 407 7.2E-150 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 A6A12_RS10155 699021a57e972999c39680d3ac9f7750 376 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 7 353 4.6E-133 T 28-03-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 A6A12_RS10155 699021a57e972999c39680d3ac9f7750 376 Pfam PF01312 FlhB HrpN YscU SpaS Family 7 347 3.9E-121 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A6A12_RS10155 699021a57e972999c39680d3ac9f7750 376 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 302 323 1.3E-38 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A6A12_RS10155 699021a57e972999c39680d3ac9f7750 376 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 228 245 1.3E-38 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A6A12_RS10155 699021a57e972999c39680d3ac9f7750 376 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 272 287 1.3E-38 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A6A12_RS10155 699021a57e972999c39680d3ac9f7750 376 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 10 32 1.3E-38 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A6A12_RS10155 699021a57e972999c39680d3ac9f7750 376 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 208 226 1.3E-38 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 A6A12_RS10155 699021a57e972999c39680d3ac9f7750 376 Gene3D G3DSA:3.40.1690.10 218 353 4.9E-55 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal A6A12_RS10155 699021a57e972999c39680d3ac9f7750 376 SUPERFAMILY SSF160544 250 355 5.49E-39 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal A6A12_RS10145 f0d4802201b4267e98f937749f032622 310 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 204 210 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A6A12_RS10145 f0d4802201b4267e98f937749f032622 310 PIRSF PIRSF037167 2 307 2.0E-150 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 A6A12_RS10145 f0d4802201b4267e98f937749f032622 310 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 13 295 2.1E-138 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 A6A12_RS10145 f0d4802201b4267e98f937749f032622 310 Gene3D G3DSA:1.10.8.10 14 101 3.5E-10 T 28-03-2018 A6A12_RS10145 f0d4802201b4267e98f937749f032622 310 Pfam PF05175 Methyltransferase small domain 135 216 4.2E-18 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 A6A12_RS10145 f0d4802201b4267e98f937749f032622 310 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 6 300 53.928 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 A6A12_RS10145 f0d4802201b4267e98f937749f032622 310 SUPERFAMILY SSF53335 16 293 2.54E-50 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS10145 f0d4802201b4267e98f937749f032622 310 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 15 301 4.6E-98 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 A6A12_RS10145 f0d4802201b4267e98f937749f032622 310 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 72 267 1.6E-60 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 A6A12_RS10145 f0d4802201b4267e98f937749f032622 310 Gene3D G3DSA:3.40.50.150 102 273 1.6E-37 T 28-03-2018 A6A12_RS05560 631336ed59bef6cf4a0490492b78f72f 301 Pfam PF03956 Lysine exporter LysO 112 297 2.3E-52 T 28-03-2018 IPR005642 Lysine exporter LysO A6A12_RS05560 631336ed59bef6cf4a0490492b78f72f 301 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 134 299 6.0E-79 T 28-03-2018 IPR005642 Lysine exporter LysO A6A12_RS09070 7cb48b83fe04e5670d09c76d6b156ab7 196 TIGRFAM TIGR02722 lp_: uncharacterized lipoprotein 5 187 8.1E-74 T 28-03-2018 IPR014094 Penicillin-binding protein activator LpoB A6A12_RS09070 7cb48b83fe04e5670d09c76d6b156ab7 196 Pfam PF13036 Peptidoglycan-synthase activator LpoB 41 185 1.3E-54 T 28-03-2018 IPR014094 Penicillin-binding protein activator LpoB A6A12_RS09070 7cb48b83fe04e5670d09c76d6b156ab7 196 Gene3D G3DSA:3.40.50.10070 58 194 2.0E-17 T 28-03-2018 A6A12_RS14240 60382ad0f1b3695a3c6d1d35c9413c71 69 Gene3D G3DSA:3.10.20.30 4 69 2.2E-17 T 28-03-2018 IPR012675 Beta-grasp domain A6A12_RS14240 60382ad0f1b3695a3c6d1d35c9413c71 69 Pfam PF02597 ThiS family 7 69 4.3E-11 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 A6A12_RS14240 60382ad0f1b3695a3c6d1d35c9413c71 69 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 6 69 1.4E-15 T 28-03-2018 IPR010035 ThiS, thiamine-biosynthesis A6A12_RS14240 60382ad0f1b3695a3c6d1d35c9413c71 69 SUPERFAMILY SSF54285 4 69 3.63E-15 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A6A12_RS06390 742a2e01a57284119c270ba594d57942 323 PIRSF PIRSF017082 5 323 4.6E-83 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 A6A12_RS06390 742a2e01a57284119c270ba594d57942 323 SUPERFAMILY SSF53850 36 275 2.17E-9 T 28-03-2018 A6A12_RS06390 742a2e01a57284119c270ba594d57942 323 Gene3D G3DSA:3.40.190.10 120 228 7.1E-14 T 28-03-2018 A6A12_RS06390 742a2e01a57284119c270ba594d57942 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 70 320 1.3E-24 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 Gene3D G3DSA:3.30.499.10 5 232 6.3E-60 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 Pfam PF00694 Aconitase C-terminal domain 662 791 2.6E-29 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 Pfam PF00330 Aconitase family (aconitate hydratase) 75 538 4.3E-145 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 Gene3D G3DSA:3.40.1060.10 233 363 9.5E-40 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 Gene3D G3DSA:3.20.19.10 625 867 1.9E-66 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 SUPERFAMILY SSF53732 27 598 8.63E-187 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 SUPERFAMILY SSF52016 603 865 1.57E-66 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 TIGRFAM TIGR02333 2met_isocit_dHY: 2-methylisocitrate dehydratase, Fe/S-dependent 7 867 0.0 T 28-03-2018 IPR012708 2-methylisocitrate dehydratase AcnD, Fe/S-dependent GO:0019679 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 Gene3D G3DSA:3.30.499.10 364 552 1.0E-55 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 PRINTS PR00415 Aconitase family signature 167 175 4.1E-25 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 PRINTS PR00415 Aconitase family signature 210 225 4.1E-25 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 PRINTS PR00415 Aconitase family signature 365 379 4.1E-25 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 PRINTS PR00415 Aconitase family signature 272 285 4.1E-25 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 PRINTS PR00415 Aconitase family signature 286 299 4.1E-25 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 PRINTS PR00415 Aconitase family signature 469 482 4.1E-25 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 PRINTS PR00415 Aconitase family signature 196 209 4.1E-25 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 PRINTS PR00415 Aconitase family signature 407 418 4.1E-25 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS06415 f8ad9e4b9ca6cb1ec57832c06dcc5792 868 PRINTS PR00415 Aconitase family signature 143 156 4.1E-25 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11015 cd08fa4527c214b5e618763345d2cd36 365 Gene3D G3DSA:3.40.630.10 52 302 9.1E-25 T 28-03-2018 A6A12_RS11015 cd08fa4527c214b5e618763345d2cd36 365 SUPERFAMILY SSF53187 33 327 1.39E-73 T 28-03-2018 A6A12_RS11015 cd08fa4527c214b5e618763345d2cd36 365 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 60 326 7.2E-67 T 28-03-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 A6A12_RS11015 cd08fa4527c214b5e618763345d2cd36 365 PIRSF PIRSF039012 14 334 1.4E-93 T 28-03-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 A6A12_RS01665 b7ea8fcf1a758ffe7577181a52a39932 162 Pfam PF04093 rod shape-determining protein MreD 9 154 1.5E-39 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 A6A12_RS01665 b7ea8fcf1a758ffe7577181a52a39932 162 PIRSF PIRSF018472 1 162 6.5E-41 T 28-03-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type A6A12_RS01665 b7ea8fcf1a758ffe7577181a52a39932 162 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 10 154 4.1E-36 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 A6A12_RS11430 e11aafaee1ae0b22c90bc82749772eac 158 PIRSF PIRSF026426 8 158 2.6E-45 T 28-03-2018 IPR010865 Protein of unknown function DUF1499 A6A12_RS11430 e11aafaee1ae0b22c90bc82749772eac 158 Pfam PF07386 Protein of unknown function (DUF1499) 46 151 2.5E-22 T 28-03-2018 IPR010865 Protein of unknown function DUF1499 A6A12_RS06925 52e8f4038422dff7a59e682e1b1c02e9 446 Gene3D G3DSA:1.20.5.110 26 401 6.8E-5 T 28-03-2018 A6A12_RS06925 52e8f4038422dff7a59e682e1b1c02e9 446 Pfam PF01618 MotA/TolQ/ExbB proton channel family 304 423 2.9E-31 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 A6A12_RS06925 52e8f4038422dff7a59e682e1b1c02e9 446 PIRSF PIRSF037714 1 446 3.6E-150 T 28-03-2018 IPR017270 Putative MotA/TolQ/ExbB family protein A6A12_RS01450 38fcbe0d9d1ef2195b61b3f8b906a840 69 Pfam PF09583 Phage shock protein G (Phageshock_PspG) 1 64 5.9E-23 T 28-03-2018 IPR014318 Phage shock protein, PspG A6A12_RS01450 38fcbe0d9d1ef2195b61b3f8b906a840 69 TIGRFAM TIGR02975 phageshock_pspG: phage shock protein G 3 64 8.0E-16 T 28-03-2018 IPR014318 Phage shock protein, PspG A6A12_RS10080 5c2fbb2e429025c4a270e0dfe08228d4 148 Pfam PF03788 LrgA family 27 120 1.2E-27 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 A6A12_RS10875 c8a1b9c6126e2d837cc59a03669c9dfd 452 Pfam PF13180 PDZ domain 225 289 8.8E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS10875 c8a1b9c6126e2d837cc59a03669c9dfd 452 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 4 452 1.3E-136 T 28-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 A6A12_RS10875 c8a1b9c6126e2d837cc59a03669c9dfd 452 Gene3D G3DSA:2.30.42.10 28 196 9.8E-12 T 28-03-2018 A6A12_RS10875 c8a1b9c6126e2d837cc59a03669c9dfd 452 SUPERFAMILY SSF50156 195 291 2.76E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS10875 c8a1b9c6126e2d837cc59a03669c9dfd 452 Gene3D G3DSA:2.30.42.10 223 311 5.5E-18 T 28-03-2018 A6A12_RS10875 c8a1b9c6126e2d837cc59a03669c9dfd 452 Pfam PF02163 Peptidase family M50 11 440 8.7E-86 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 A6A12_RS10875 c8a1b9c6126e2d837cc59a03669c9dfd 452 SUPERFAMILY SSF50156 91 186 1.45E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS10875 c8a1b9c6126e2d837cc59a03669c9dfd 452 SMART SM00228 212 281 8.5E-7 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS10875 c8a1b9c6126e2d837cc59a03669c9dfd 452 SMART SM00228 115 186 0.0012 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS13560 752fd0f055b5f0e58039aed0b9a23284 405 Pfam PF13356 Arm DNA-binding domain 5 89 1.8E-16 T 28-03-2018 IPR025166 Integrase, DNA-binding domain A6A12_RS13560 752fd0f055b5f0e58039aed0b9a23284 405 Gene3D G3DSA:1.10.150.130 86 201 4.2E-11 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A6A12_RS13560 752fd0f055b5f0e58039aed0b9a23284 405 Pfam PF00589 Phage integrase family 205 374 4.3E-14 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS13560 752fd0f055b5f0e58039aed0b9a23284 405 SUPERFAMILY SSF56349 97 394 9.42E-51 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS13560 752fd0f055b5f0e58039aed0b9a23284 405 Gene3D G3DSA:1.10.443.10 202 399 1.4E-25 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS07265 91ef8e48369e89cb6550fdab0bad6c08 70 Pfam PF00313 'Cold-shock' DNA-binding domain 6 68 4.7E-30 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A6A12_RS07265 91ef8e48369e89cb6550fdab0bad6c08 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 28-03-2018 IPR019844 Cold-shock conserved site A6A12_RS07265 91ef8e48369e89cb6550fdab0bad6c08 70 PIRSF PIRSF002599 1 70 5.7E-25 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 A6A12_RS07265 91ef8e48369e89cb6550fdab0bad6c08 70 Gene3D G3DSA:2.40.50.140 1 70 8.7E-28 T 28-03-2018 A6A12_RS07265 91ef8e48369e89cb6550fdab0bad6c08 70 PRINTS PR00050 Cold shock protein signature 7 22 8.8E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A6A12_RS07265 91ef8e48369e89cb6550fdab0bad6c08 70 PRINTS PR00050 Cold shock protein signature 28 37 8.8E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A6A12_RS07265 91ef8e48369e89cb6550fdab0bad6c08 70 PRINTS PR00050 Cold shock protein signature 43 61 8.8E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A6A12_RS07265 91ef8e48369e89cb6550fdab0bad6c08 70 SUPERFAMILY SSF50249 4 68 4.07E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS07265 91ef8e48369e89cb6550fdab0bad6c08 70 SMART SM00357 6 70 1.6E-30 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 332 2.3E-132 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 158 330 4.9E-55 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 SUPERFAMILY SSF53671 4 333 3.27E-96 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 1.2E-44 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 277 1.9E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 297 320 1.9E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 1.9E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 1.9E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 333 82.451 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 2.3E-31 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 311 322 2.3E-31 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 2.3E-31 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 2.3E-31 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 230 240 2.3E-31 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 Gene3D G3DSA:3.40.50.1370 1 144 5.8E-51 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS12060 68651fe9b4c512c635e3abe67466dae6 334 Gene3D G3DSA:3.40.50.1370 145 319 1.0E-51 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A6A12_RS06315 728221f4b73ebe7a0c3d769dd7b1611c 98 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 87 5.1E-34 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 A6A12_RS06315 728221f4b73ebe7a0c3d769dd7b1611c 98 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 95 9.9E-21 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A6A12_RS06315 728221f4b73ebe7a0c3d769dd7b1611c 98 SUPERFAMILY SSF52794 2 97 2.96E-35 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 A6A12_RS06315 728221f4b73ebe7a0c3d769dd7b1611c 98 Gene3D G3DSA:3.40.50.2300 2 98 9.8E-40 T 28-03-2018 A6A12_RS11950 e2ed14f22e27374ab2181adf1a4bd9a0 200 Gene3D G3DSA:3.20.19.10 1 176 9.0E-50 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A6A12_RS11950 e2ed14f22e27374ab2181adf1a4bd9a0 200 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 199 44.059 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A6A12_RS11950 e2ed14f22e27374ab2181adf1a4bd9a0 200 Pfam PF00694 Aconitase C-terminal domain 1 125 1.4E-38 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 A6A12_RS11950 e2ed14f22e27374ab2181adf1a4bd9a0 200 SUPERFAMILY SSF52016 1 196 1.45E-60 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel A6A12_RS11950 e2ed14f22e27374ab2181adf1a4bd9a0 200 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 188 4.2E-99 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 A6A12_RS00635 5f44d9e3f8b3be40b275f036058b2ded 369 SUPERFAMILY SSF53335 9 367 6.69E-56 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS00635 5f44d9e3f8b3be40b275f036058b2ded 369 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 11 367 1.3E-189 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A6A12_RS00635 5f44d9e3f8b3be40b275f036058b2ded 369 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 350 360 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site A6A12_RS00635 5f44d9e3f8b3be40b275f036058b2ded 369 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 301 330 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site A6A12_RS00635 5f44d9e3f8b3be40b275f036058b2ded 369 TIGRFAM TIGR02143 trmA_only: tRNA (uracil(54)-C(5))-methyltransferase 11 367 6.8E-186 T 28-03-2018 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 A6A12_RS00635 5f44d9e3f8b3be40b275f036058b2ded 369 Gene3D G3DSA:3.40.50.150 122 368 1.4E-33 T 28-03-2018 A6A12_RS00635 5f44d9e3f8b3be40b275f036058b2ded 369 Hamap MF_01011 tRNA/tmRNA (uracil-C(5))-methyltransferase [trmA]. 4 368 44.408 T 28-03-2018 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 A6A12_RS13725 6f3f702bad50afde27a3ac6578c7bb38 698 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 50 - T 28-03-2018 IPR010916 TonB box, conserved site A6A12_RS13725 6f3f702bad50afde27a3ac6578c7bb38 698 Gene3D G3DSA:2.40.170.20 170 698 3.0E-69 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A6A12_RS13725 6f3f702bad50afde27a3ac6578c7bb38 698 Gene3D G3DSA:2.170.130.10 33 169 1.4E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 A6A12_RS13725 6f3f702bad50afde27a3ac6578c7bb38 698 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 60 697 2.7E-92 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 A6A12_RS13725 6f3f702bad50afde27a3ac6578c7bb38 698 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 157 1.7E-16 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 A6A12_RS13725 6f3f702bad50afde27a3ac6578c7bb38 698 Pfam PF00593 TonB dependent receptor 247 697 1.2E-50 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 A6A12_RS13725 6f3f702bad50afde27a3ac6578c7bb38 698 SUPERFAMILY SSF56935 31 698 3.4E-112 T 28-03-2018 A6A12_RS01905 0ff69228c94d8ef4ab2ba6370ce2e0b7 143 Pfam PF14467 Domain of unknown function (DUF4426) 23 142 2.8E-48 T 28-03-2018 IPR025218 Domain of unknown function DUF4426 A6A12_RS10000 b69770253b24eed01a3e6e8556403adf 388 SUPERFAMILY SSF56059 1 238 1.04E-79 T 28-03-2018 A6A12_RS10000 b69770253b24eed01a3e6e8556403adf 388 PIRSF PIRSF001554 1 388 8.0E-154 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A6A12_RS10000 b69770253b24eed01a3e6e8556403adf 388 Pfam PF08442 ATP-grasp domain 2 203 1.7E-78 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A6A12_RS10000 b69770253b24eed01a3e6e8556403adf 388 Gene3D G3DSA:3.40.50.261 240 385 4.1E-42 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A6A12_RS10000 b69770253b24eed01a3e6e8556403adf 388 SUPERFAMILY SSF52210 239 385 4.71E-54 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A6A12_RS10000 b69770253b24eed01a3e6e8556403adf 388 Gene3D G3DSA:3.30.470.20 96 239 2.9E-53 T 28-03-2018 A6A12_RS10000 b69770253b24eed01a3e6e8556403adf 388 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 43.138 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A6A12_RS10000 b69770253b24eed01a3e6e8556403adf 388 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A6A12_RS10000 b69770253b24eed01a3e6e8556403adf 388 Gene3D G3DSA:3.30.1490.20 21 95 6.4E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A6A12_RS10000 b69770253b24eed01a3e6e8556403adf 388 Pfam PF00549 CoA-ligase 262 382 9.2E-25 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A6A12_RS10000 b69770253b24eed01a3e6e8556403adf 388 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 2.4E-172 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 A6A12_RS09350 3a637ca668b2f3cf3ed7852191835b4c 287 SUPERFAMILY SSF103481 185 283 7.45E-15 T 28-03-2018 A6A12_RS09350 3a637ca668b2f3cf3ed7852191835b4c 287 Pfam PF00892 EamA-like transporter family 7 137 2.1E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A6A12_RS09350 3a637ca668b2f3cf3ed7852191835b4c 287 Pfam PF00892 EamA-like transporter family 148 278 5.5E-19 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A6A12_RS09350 3a637ca668b2f3cf3ed7852191835b4c 287 SUPERFAMILY SSF103481 41 140 5.36E-11 T 28-03-2018 A6A12_RS14110 7b9de3904099430cfb051356ad2e6b73 297 Pfam PF00892 EamA-like transporter family 9 141 1.3E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A6A12_RS14110 7b9de3904099430cfb051356ad2e6b73 297 Pfam PF00892 EamA-like transporter family 155 286 5.0E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A6A12_RS14110 7b9de3904099430cfb051356ad2e6b73 297 SUPERFAMILY SSF103481 44 144 9.81E-13 T 28-03-2018 A6A12_RS14110 7b9de3904099430cfb051356ad2e6b73 297 SUPERFAMILY SSF103481 189 289 1.83E-8 T 28-03-2018 A6A12_RS04650 50c8ca959fd9cfbb6173762c46be86bb 348 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 8 348 2.6E-140 T 28-03-2018 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 A6A12_RS04650 50c8ca959fd9cfbb6173762c46be86bb 348 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 3 348 27.298 T 28-03-2018 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 A6A12_RS04650 50c8ca959fd9cfbb6173762c46be86bb 348 Pfam PF03116 NQR2, RnfD, RnfE family 6 347 3.2E-105 T 28-03-2018 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 A6A12_RS08800 800d8c191133d97297c919ce703fb55e 147 Pfam PF02472 Biopolymer transport protein ExbD/TolR 9 144 3.7E-26 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 A6A12_RS08800 800d8c191133d97297c919ce703fb55e 147 TIGRFAM TIGR02801 tolR: protein TolR 12 144 2.1E-38 T 28-03-2018 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 A6A12_RS02520 08c2bf0489423ddb43e47c92d1f22132 316 SUPERFAMILY SSF50129 4 154 6.7E-36 T 28-03-2018 IPR011032 GroES-like A6A12_RS02520 08c2bf0489423ddb43e47c92d1f22132 316 Gene3D G3DSA:3.90.180.10 157 314 2.1E-16 T 28-03-2018 A6A12_RS02520 08c2bf0489423ddb43e47c92d1f22132 316 SMART SM00829 12 312 4.7E-14 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A6A12_RS02520 08c2bf0489423ddb43e47c92d1f22132 316 Gene3D G3DSA:3.90.180.10 2 156 3.7E-48 T 28-03-2018 A6A12_RS02520 08c2bf0489423ddb43e47c92d1f22132 316 SUPERFAMILY SSF51735 122 246 6.93E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS02520 08c2bf0489423ddb43e47c92d1f22132 316 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 92 2.4E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A6A12_RS02520 08c2bf0489423ddb43e47c92d1f22132 316 Pfam PF13602 Zinc-binding dehydrogenase 191 312 4.4E-21 T 28-03-2018 A6A12_RS06405 18256e8d0fd7937e3a3c900db73ac0d4 298 Gene3D G3DSA:3.20.20.60 3 298 2.4E-84 T 28-03-2018 A6A12_RS06405 18256e8d0fd7937e3a3c900db73ac0d4 298 SUPERFAMILY SSF51621 6 294 2.06E-96 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A6A12_RS06405 18256e8d0fd7937e3a3c900db73ac0d4 298 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 3 296 49.895 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 A6A12_RS06405 18256e8d0fd7937e3a3c900db73ac0d4 298 ProSitePatterns PS00161 Isocitrate lyase signature. 119 124 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 A6A12_RS06405 18256e8d0fd7937e3a3c900db73ac0d4 298 Pfam PF13714 Phosphoenolpyruvate phosphomutase 15 259 8.6E-44 T 28-03-2018 A6A12_RS06405 18256e8d0fd7937e3a3c900db73ac0d4 298 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 6 295 5.2E-127 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 A6A12_RS08460 d29e83b01b2ed3e65ad6c4d02e681258 157 Pfam PF05119 Phage terminase, small subunit 53 144 3.0E-24 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family A6A12_RS08460 d29e83b01b2ed3e65ad6c4d02e681258 157 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 44 149 1.7E-29 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family A6A12_RS04215 0add6e0f002230a3a30bfe99b3bdf1cc 372 SUPERFAMILY SSF53756 2 371 5.76E-134 T 28-03-2018 A6A12_RS04215 0add6e0f002230a3a30bfe99b3bdf1cc 372 Gene3D G3DSA:3.40.50.2000 212 357 5.7E-36 T 28-03-2018 A6A12_RS04215 0add6e0f002230a3a30bfe99b3bdf1cc 372 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 23 370 8.9E-120 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 A6A12_RS04215 0add6e0f002230a3a30bfe99b3bdf1cc 372 Gene3D G3DSA:3.40.50.2000 2 211 6.4E-75 T 28-03-2018 A6A12_RS04215 0add6e0f002230a3a30bfe99b3bdf1cc 372 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 370 4.8E-158 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 A6A12_RS02670 02bc8414cacb0bc14a6ef2b5da9a69b1 176 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 7 172 8.7E-73 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 A6A12_RS02670 02bc8414cacb0bc14a6ef2b5da9a69b1 176 SUPERFAMILY SSF53271 3 175 1.44E-55 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A6A12_RS02670 02bc8414cacb0bc14a6ef2b5da9a69b1 176 Pfam PF00156 Phosphoribosyl transferase domain 15 159 7.5E-27 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A6A12_RS02670 02bc8414cacb0bc14a6ef2b5da9a69b1 176 Gene3D G3DSA:3.40.50.2020 2 176 2.1E-47 T 28-03-2018 A6A12_RS04360 0ac085627ba48e93c22d1134e814f072 373 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 324 348 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 A6A12_RS04360 0ac085627ba48e93c22d1134e814f072 373 Pfam PF01098 Cell cycle protein 24 367 1.8E-111 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 A6A12_RS04360 0ac085627ba48e93c22d1134e814f072 373 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 20 367 1.6E-134 T 28-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 A6A12_RS03015 4531231eca630a58d7f0fb9c6a6a9e4d 337 Gene3D G3DSA:3.20.20.150 10 334 3.5E-16 T 28-03-2018 A6A12_RS03015 4531231eca630a58d7f0fb9c6a6a9e4d 337 ProSitePatterns PS01276 Peptidase family U32 signature. 163 181 - T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A6A12_RS03015 4531231eca630a58d7f0fb9c6a6a9e4d 337 Pfam PF01136 Peptidase family U32 75 336 2.0E-67 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A6A12_RS03915 9c035bdae3e5a78ab01f2054db201733 166 Gene3D G3DSA:3.30.700.10 5 155 2.7E-10 T 28-03-2018 A6A12_RS03915 9c035bdae3e5a78ab01f2054db201733 166 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 25 8.6E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS03915 9c035bdae3e5a78ab01f2054db201733 166 SUPERFAMILY SSF54523 5 89 1.33E-13 T 28-03-2018 A6A12_RS03915 9c035bdae3e5a78ab01f2054db201733 166 PIRSF PIRSF024622 1 166 9.7E-57 T 28-03-2018 IPR016824 Tfp pilus assembly protein FimT A6A12_RS03915 9c035bdae3e5a78ab01f2054db201733 166 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 24 3.5E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS03915 9c035bdae3e5a78ab01f2054db201733 166 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 3 23 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS03915 9c035bdae3e5a78ab01f2054db201733 166 Pfam PF12019 Type II transport protein GspH 41 155 2.5E-11 T 28-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 A6A12_RS02345 8962dbe716c915639c08fade83ea80e8 71 Pfam PF01165 Ribosomal protein S21 4 56 5.3E-23 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02345 8962dbe716c915639c08fade83ea80e8 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 44 2.0E-10 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02345 8962dbe716c915639c08fade83ea80e8 71 Gene3D G3DSA:1.20.5.1150 16 52 1.3E-18 T 28-03-2018 A6A12_RS02345 8962dbe716c915639c08fade83ea80e8 71 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 28-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS02345 8962dbe716c915639c08fade83ea80e8 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.344 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02345 8962dbe716c915639c08fade83ea80e8 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.6E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02345 8962dbe716c915639c08fade83ea80e8 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.6E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02345 8962dbe716c915639c08fade83ea80e8 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.6E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02345 8962dbe716c915639c08fade83ea80e8 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.6E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS02345 8962dbe716c915639c08fade83ea80e8 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 4.9E-25 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS05240 3df022d12a25cb2332a48ae87a413432 389 Pfam PF13181 Tetratricopeptide repeat 180 213 0.028 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS05240 3df022d12a25cb2332a48ae87a413432 389 Gene3D G3DSA:1.25.40.10 204 279 6.7E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS05240 3df022d12a25cb2332a48ae87a413432 389 Gene3D G3DSA:1.25.40.10 119 203 1.2E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS05240 3df022d12a25cb2332a48ae87a413432 389 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 4 387 37.27 T 28-03-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 A6A12_RS05240 3df022d12a25cb2332a48ae87a413432 389 SMART SM00028 180 213 0.06 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS05240 3df022d12a25cb2332a48ae87a413432 389 SMART SM00028 69 102 69.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS05240 3df022d12a25cb2332a48ae87a413432 389 SMART SM00028 214 247 43.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS05240 3df022d12a25cb2332a48ae87a413432 389 SUPERFAMILY SSF81901 39 246 7.32E-17 T 28-03-2018 A6A12_RS05240 3df022d12a25cb2332a48ae87a413432 389 Gene3D G3DSA:1.25.40.10 18 118 3.9E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS05240 3df022d12a25cb2332a48ae87a413432 389 Pfam PF13176 Tetratricopeptide repeat 71 94 0.017 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS04640 b5b2ef850ee31a566c52a156b15deceb 230 PIRSF PIRSF006102 1 219 7.5E-77 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 A6A12_RS04640 b5b2ef850ee31a566c52a156b15deceb 230 Pfam PF02508 Rnf-Nqr subunit, membrane protein 6 200 1.8E-64 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 A6A12_RS04640 b5b2ef850ee31a566c52a156b15deceb 230 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 6 208 6.5E-86 T 28-03-2018 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 A6A12_RS04640 b5b2ef850ee31a566c52a156b15deceb 230 Hamap MF_00478 Electron transport complex subunit RsxE [rsxE]. 1 210 27.796 T 28-03-2018 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 A6A12_RS04140 ab8143ccf418c86a5989d4281331cb02 344 Pfam PF00005 ABC transporter 21 169 4.6E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS04140 ab8143ccf418c86a5989d4281331cb02 344 SMART SM00382 30 235 1.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS04140 ab8143ccf418c86a5989d4281331cb02 344 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS04140 ab8143ccf418c86a5989d4281331cb02 344 Pfam PF09383 NIL domain 268 339 1.1E-20 T 28-03-2018 IPR018449 NIL domain A6A12_RS04140 ab8143ccf418c86a5989d4281331cb02 344 SMART SM00930 265 340 6.5E-27 T 28-03-2018 IPR018449 NIL domain A6A12_RS04140 ab8143ccf418c86a5989d4281331cb02 344 TIGRFAM TIGR02314 ABC_MetN: D-methionine ABC transporter, ATP-binding protein 1 343 5.8E-198 T 28-03-2018 IPR012692 ABC transporter, methionine import, ATP-binding protein MetN, proteobacteria GO:0005524|GO:0009276|GO:0048473|GO:0048474 A6A12_RS04140 ab8143ccf418c86a5989d4281331cb02 344 SUPERFAMILY SSF52540 1 239 1.09E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS04140 ab8143ccf418c86a5989d4281331cb02 344 Gene3D G3DSA:3.30.70.260 255 344 1.1E-26 T 28-03-2018 A6A12_RS04140 ab8143ccf418c86a5989d4281331cb02 344 Gene3D G3DSA:3.40.50.300 1 254 1.6E-74 T 28-03-2018 A6A12_RS04140 ab8143ccf418c86a5989d4281331cb02 344 SUPERFAMILY SSF55021 248 343 2.52E-25 T 28-03-2018 A6A12_RS02225 09d7033e37d1744fcdb02369521be00a 510 Gene3D G3DSA:1.10.10.60 1 51 0.0011 T 28-03-2018 A6A12_RS02225 09d7033e37d1744fcdb02369521be00a 510 SUPERFAMILY SSF53098 167 301 4.05E-6 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS02225 09d7033e37d1744fcdb02369521be00a 510 Gene3D G3DSA:3.30.420.10 129 352 9.8E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS02225 09d7033e37d1744fcdb02369521be00a 510 Pfam PF00665 Integrase core domain 140 267 3.3E-16 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 A6A12_RS12920 1d08040951afc3e496fb5d25c987b2a3 108 ProDom PD020365 REPRESSOR MET BIOSYNTHESIS TRANSCRIPTION METJ METHIONINE REGULON DNA-BINDING REGULATORY AMINO-ACID 10 101 3.0E-49 T 28-03-2018 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 A6A12_RS12920 1d08040951afc3e496fb5d25c987b2a3 108 Pfam PF01340 Met Apo-repressor, MetJ 3 99 3.8E-59 T 28-03-2018 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 A6A12_RS12920 1d08040951afc3e496fb5d25c987b2a3 108 Hamap MF_00744 Met repressor [metJ]. 1 105 34.879 T 28-03-2018 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 A6A12_RS12920 1d08040951afc3e496fb5d25c987b2a3 108 Gene3D G3DSA:1.10.140.10 3 103 8.5E-59 T 28-03-2018 IPR023453 Methionine repressor MetJ domain A6A12_RS12920 1d08040951afc3e496fb5d25c987b2a3 108 SUPERFAMILY SSF47598 3 103 9.12E-57 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 A6A12_RS14170 00652787ea05c0520b0d216aac369ab3 107 Hamap MF_01088 Universal stress protein B [uspB]. 1 107 34.986 T 28-03-2018 IPR019598 Universal stress protein B A6A12_RS14170 00652787ea05c0520b0d216aac369ab3 107 Pfam PF10625 Universal stress protein B (UspB) 1 104 5.8E-48 T 28-03-2018 IPR019598 Universal stress protein B A6A12_RS13735 a060a7ba85b21d84d0e697f07e89820f 482 Pfam PF02378 Phosphotransferase system, EIIC 128 409 7.6E-30 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 A6A12_RS13735 a060a7ba85b21d84d0e697f07e89820f 482 Pfam PF00367 phosphotransferase system, EIIB 11 43 1.8E-10 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A6A12_RS13735 a060a7ba85b21d84d0e697f07e89820f 482 SUPERFAMILY SSF55604 8 80 6.28E-18 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A6A12_RS13735 a060a7ba85b21d84d0e697f07e89820f 482 Gene3D G3DSA:3.30.1360.60 6 83 8.8E-24 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 A6A12_RS13735 a060a7ba85b21d84d0e697f07e89820f 482 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 A6A12_RS13690 dff903309f270e1cbb4708cddb342858 962 SUPERFAMILY SSF51445 626 734 1.79E-31 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A6A12_RS13690 dff903309f270e1cbb4708cddb342858 962 SUPERFAMILY SSF51445 772 821 1.79E-31 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A6A12_RS13690 dff903309f270e1cbb4708cddb342858 962 SUPERFAMILY SSF51445 849 945 1.79E-31 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A6A12_RS13690 dff903309f270e1cbb4708cddb342858 962 Pfam PF00704 Glycosyl hydrolases family 18 629 939 1.5E-14 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 A6A12_RS13690 dff903309f270e1cbb4708cddb342858 962 Gene3D G3DSA:2.60.40.10 551 613 0.01 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS13690 dff903309f270e1cbb4708cddb342858 962 Gene3D G3DSA:2.60.40.10 454 507 0.001 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS13690 dff903309f270e1cbb4708cddb342858 962 Gene3D G3DSA:2.60.40.10 291 355 1.5E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS13690 dff903309f270e1cbb4708cddb342858 962 Gene3D G3DSA:3.20.20.80 621 951 9.3E-37 T 28-03-2018 A6A12_RS13690 dff903309f270e1cbb4708cddb342858 962 Gene3D G3DSA:2.10.10.20 356 421 1.5E-8 T 28-03-2018 A6A12_RS13690 dff903309f270e1cbb4708cddb342858 962 Gene3D G3DSA:2.40.50.70 508 550 3.4E-7 T 28-03-2018 A6A12_RS13690 dff903309f270e1cbb4708cddb342858 962 Gene3D G3DSA:2.40.50.70 232 290 4.3E-9 T 28-03-2018 A6A12_RS13690 dff903309f270e1cbb4708cddb342858 962 Gene3D G3DSA:2.40.50.70 422 453 0.0051 T 28-03-2018 A6A12_RS13690 dff903309f270e1cbb4708cddb342858 962 SMART SM00636 626 941 0.0076 T 28-03-2018 IPR011583 Chitinase II GO:0008061 A6A12_RS11955 03bda75ea0540731e1ee250fcb409f35 261 Pfam PF04784 Protein of unknown function, DUF547 88 198 3.5E-23 T 28-03-2018 IPR006869 Domain of unknown function DUF547 A6A12_RS14090 9f82312905379c72f1c73d6df2d90915 544 Pfam PF03109 ABC1 family 112 230 6.5E-36 T 28-03-2018 IPR004147 UbiB domain A6A12_RS14090 9f82312905379c72f1c73d6df2d90915 544 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 3 539 56.504 T 28-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 A6A12_RS14090 9f82312905379c72f1c73d6df2d90915 544 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 6 445 3.9E-176 T 28-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 A6A12_RS14090 9f82312905379c72f1c73d6df2d90915 544 SUPERFAMILY SSF56112 94 158 5.11E-42 T 28-03-2018 IPR011009 Protein kinase-like domain A6A12_RS14090 9f82312905379c72f1c73d6df2d90915 544 SUPERFAMILY SSF56112 193 436 5.11E-42 T 28-03-2018 IPR011009 Protein kinase-like domain A6A12_RS14090 9f82312905379c72f1c73d6df2d90915 544 Gene3D G3DSA:3.30.200.20 104 244 2.1E-18 T 28-03-2018 A6A12_RS07895 5e231a823b0c881f35f64cb81783080e 223 Gene3D G3DSA:3.30.65.10 163 221 7.2E-11 T 28-03-2018 A6A12_RS07895 5e231a823b0c881f35f64cb81783080e 223 PIRSF PIRSF028063 1 221 1.2E-133 T 28-03-2018 IPR014538 Uncharacterised conserved protein, topoisomerase zinc finger A6A12_RS07895 5e231a823b0c881f35f64cb81783080e 223 Pfam PF10881 Protein of unknown function (DUF2726) 38 160 1.6E-37 T 28-03-2018 IPR024402 Domain of unknown function DUF2726 A6A12_RS11120 0594faccbe71be16b02cfe523fc90952 263 Gene3D G3DSA:2.40.230.20 25 263 7.3E-86 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 A6A12_RS11120 0594faccbe71be16b02cfe523fc90952 263 SUPERFAMILY SSF111364 30 263 6.02E-85 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 A6A12_RS11120 0594faccbe71be16b02cfe523fc90952 263 Pfam PF03502 Nucleoside-specific channel-forming protein, Tsx 30 263 1.5E-104 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 A6A12_RS07395 b2f4a97738b2c95e4273282366425b37 357 Pfam PF01339 CheB methylesterase 170 348 7.1E-62 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A6A12_RS07395 b2f4a97738b2c95e4273282366425b37 357 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 353 40.33 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A6A12_RS07395 b2f4a97738b2c95e4273282366425b37 357 SUPERFAMILY SSF52172 1 109 6.83E-27 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS07395 b2f4a97738b2c95e4273282366425b37 357 Gene3D G3DSA:3.40.50.180 159 357 7.4E-78 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A6A12_RS07395 b2f4a97738b2c95e4273282366425b37 357 Gene3D G3DSA:3.40.50.2300 3 158 8.6E-28 T 28-03-2018 A6A12_RS07395 b2f4a97738b2c95e4273282366425b37 357 Pfam PF00072 Response regulator receiver domain 6 109 1.2E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS07395 b2f4a97738b2c95e4273282366425b37 357 SMART SM00448 4 119 1.2E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS07395 b2f4a97738b2c95e4273282366425b37 357 SUPERFAMILY SSF52738 165 354 1.31E-71 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A6A12_RS07395 b2f4a97738b2c95e4273282366425b37 357 PIRSF PIRSF000876 1 356 1.1E-135 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A6A12_RS11155 0900a05cdece58a4daf0bd7db82826dd 155 Pfam PF11012 Protein of unknown function (DUF2850) 68 146 1.0E-31 T 28-03-2018 IPR021271 Protein of unknown function DUF2850 A6A12_RS11705 f99988742087039afefec90ae8ab0be2 418 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 283 312 1.6E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS11705 f99988742087039afefec90ae8ab0be2 418 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 68 88 1.6E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS11705 f99988742087039afefec90ae8ab0be2 418 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 254 281 1.6E-21 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS11705 f99988742087039afefec90ae8ab0be2 418 SUPERFAMILY SSF58104 109 418 3.14E-75 T 28-03-2018 A6A12_RS11705 f99988742087039afefec90ae8ab0be2 418 Gene3D G3DSA:1.10.287.950 194 418 5.2E-51 T 28-03-2018 A6A12_RS11705 f99988742087039afefec90ae8ab0be2 418 Gene3D G3DSA:1.10.287.950 50 193 7.9E-5 T 28-03-2018 A6A12_RS11705 f99988742087039afefec90ae8ab0be2 418 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 202 384 1.9E-41 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS11705 f99988742087039afefec90ae8ab0be2 418 SMART SM00283 156 417 2.7E-70 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS14025 d744e4d3fb1b162c69d77d684066e023 462 SMART SM00729 57 277 2.9E-53 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 A6A12_RS14025 d744e4d3fb1b162c69d77d684066e023 462 SUPERFAMILY SSF102114 11 449 1.11E-143 T 28-03-2018 A6A12_RS14025 d744e4d3fb1b162c69d77d684066e023 462 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 13 462 1.7E-207 T 28-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 A6A12_RS14025 d744e4d3fb1b162c69d77d684066e023 462 PIRSF PIRSF000167 8 459 1.9E-171 T 28-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 A6A12_RS14025 d744e4d3fb1b162c69d77d684066e023 462 Pfam PF06969 HemN C-terminal domain 368 436 7.9E-12 T 28-03-2018 IPR010723 HemN, C-terminal A6A12_RS14025 d744e4d3fb1b162c69d77d684066e023 462 Pfam PF04055 Radical SAM superfamily 62 231 6.3E-18 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A6A12_RS14025 d744e4d3fb1b162c69d77d684066e023 462 Gene3D G3DSA:3.20.20.70 38 358 5.6E-45 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS01815 6b36c7b06e8e221654fe76f4e5aa95c5 789 Pfam PF04453 Organic solvent tolerance protein 297 690 2.5E-114 T 28-03-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 A6A12_RS01815 6b36c7b06e8e221654fe76f4e5aa95c5 789 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 4 761 20.631 T 28-03-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 A6A12_RS01815 6b36c7b06e8e221654fe76f4e5aa95c5 789 Pfam PF03968 OstA-like protein 57 189 2.2E-17 T 28-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal A6A12_RS01815 6b36c7b06e8e221654fe76f4e5aa95c5 789 Gene3D G3DSA:2.60.450.10 47 202 5.7E-22 T 28-03-2018 A6A12_RS04490 17a7b723dbdff64709234bc60b430e4b 307 SUPERFAMILY SSF117892 53 187 1.29E-41 T 28-03-2018 IPR001107 Band 7 domain A6A12_RS04490 17a7b723dbdff64709234bc60b430e4b 307 SMART SM00244 22 180 3.3E-57 T 28-03-2018 IPR001107 Band 7 domain A6A12_RS04490 17a7b723dbdff64709234bc60b430e4b 307 ProSitePatterns PS01270 Band 7 protein family signature. 136 164 - T 28-03-2018 IPR018080 Band 7/stomatin-like, conserved site A6A12_RS04490 17a7b723dbdff64709234bc60b430e4b 307 PRINTS PR00721 Stomatin signature 175 196 9.5E-29 T 28-03-2018 IPR001972 Stomatin family GO:0016020 A6A12_RS04490 17a7b723dbdff64709234bc60b430e4b 307 PRINTS PR00721 Stomatin signature 132 155 9.5E-29 T 28-03-2018 IPR001972 Stomatin family GO:0016020 A6A12_RS04490 17a7b723dbdff64709234bc60b430e4b 307 PRINTS PR00721 Stomatin signature 77 98 9.5E-29 T 28-03-2018 IPR001972 Stomatin family GO:0016020 A6A12_RS04490 17a7b723dbdff64709234bc60b430e4b 307 PRINTS PR00721 Stomatin signature 112 129 9.5E-29 T 28-03-2018 IPR001972 Stomatin family GO:0016020 A6A12_RS04490 17a7b723dbdff64709234bc60b430e4b 307 PRINTS PR00721 Stomatin signature 156 174 9.5E-29 T 28-03-2018 IPR001972 Stomatin family GO:0016020 A6A12_RS04490 17a7b723dbdff64709234bc60b430e4b 307 Pfam PF01145 SPFH domain / Band 7 family 26 195 3.6E-33 T 28-03-2018 IPR001107 Band 7 domain A6A12_RS00785 c5e8e848d2ea96292847f73575165c65 334 Hamap MF_00540 Adenosine deaminase [add]. 1 331 54.168 T 28-03-2018 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 A6A12_RS00785 c5e8e848d2ea96292847f73575165c65 334 Gene3D G3DSA:3.20.20.140 1 333 6.3E-72 T 28-03-2018 A6A12_RS00785 c5e8e848d2ea96292847f73575165c65 334 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 6 329 8.3E-120 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 A6A12_RS00785 c5e8e848d2ea96292847f73575165c65 334 Pfam PF00962 Adenosine/AMP deaminase 5 326 1.4E-89 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 A6A12_RS00785 c5e8e848d2ea96292847f73575165c65 334 SUPERFAMILY SSF51556 4 329 2.08E-74 T 28-03-2018 IPR032466 Metal-dependent hydrolase A6A12_RS07495 e7c56e373a190c686d63b9c6592f2b80 517 SUPERFAMILY SSF47090 197 270 8.63E-11 T 28-03-2018 IPR002477 Peptidoglycan binding-like A6A12_RS07495 e7c56e373a190c686d63b9c6592f2b80 517 Pfam PF03734 L,D-transpeptidase catalytic domain 291 458 1.1E-28 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 A6A12_RS07495 e7c56e373a190c686d63b9c6592f2b80 517 Gene3D G3DSA:2.40.440.10 289 459 1.8E-23 T 28-03-2018 A6A12_RS07495 e7c56e373a190c686d63b9c6592f2b80 517 Gene3D G3DSA:1.10.101.10 93 269 2.5E-11 T 28-03-2018 IPR002477 Peptidoglycan binding-like A6A12_RS07495 e7c56e373a190c686d63b9c6592f2b80 517 SUPERFAMILY SSF141523 288 343 6.67E-18 T 28-03-2018 A6A12_RS07495 e7c56e373a190c686d63b9c6592f2b80 517 SUPERFAMILY SSF141523 399 450 6.67E-18 T 28-03-2018 A6A12_RS07495 e7c56e373a190c686d63b9c6592f2b80 517 Pfam PF01471 Putative peptidoglycan binding domain 230 263 1.0E-7 T 28-03-2018 IPR002477 Peptidoglycan binding-like A6A12_RS02020 e0c7505f3a65030c70d4e102781db518 298 Hamap MF_00513 HTH-type transcriptional regulator ArgP [argP]. 1 298 54.494 T 28-03-2018 IPR023490 HTH-type transcriptional regulator ArgP, Gammaproteobacteria A6A12_RS02020 e0c7505f3a65030c70d4e102781db518 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 9.0E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS02020 e0c7505f3a65030c70d4e102781db518 298 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 4 296 1.2E-104 T 28-03-2018 IPR017685 HTH-type transcriptional regulator ArgP A6A12_RS02020 e0c7505f3a65030c70d4e102781db518 298 Pfam PF03466 LysR substrate binding domain 97 257 7.7E-12 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS02020 e0c7505f3a65030c70d4e102781db518 298 Gene3D G3DSA:3.40.190.10 180 265 5.7E-9 T 28-03-2018 A6A12_RS02020 e0c7505f3a65030c70d4e102781db518 298 Gene3D G3DSA:1.10.10.10 1 88 2.9E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS02020 e0c7505f3a65030c70d4e102781db518 298 SUPERFAMILY SSF46785 4 112 2.56E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS02020 e0c7505f3a65030c70d4e102781db518 298 SUPERFAMILY SSF53850 95 295 8.32E-21 T 28-03-2018 A6A12_RS02020 e0c7505f3a65030c70d4e102781db518 298 Gene3D G3DSA:3.40.190.10 94 179 1.3E-33 T 28-03-2018 A6A12_RS02020 e0c7505f3a65030c70d4e102781db518 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS02020 e0c7505f3a65030c70d4e102781db518 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS02020 e0c7505f3a65030c70d4e102781db518 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS04965 4c628e91d01c6fafe383dfa8172437e3 274 Pfam PF11207 Protein of unknown function (DUF2989) 16 218 1.0E-74 T 28-03-2018 IPR021372 Protein of unknown function DUF2989 A6A12_RS04965 4c628e91d01c6fafe383dfa8172437e3 274 Gene3D G3DSA:1.25.40.10 75 215 6.5E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS03180 279b53fc511dcd438a9b6d3d59362a1f 86 Pfam PF01649 Ribosomal protein S20 2 84 2.9E-26 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS03180 279b53fc511dcd438a9b6d3d59362a1f 86 Gene3D G3DSA:1.20.58.110 1 86 1.4E-28 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS03180 279b53fc511dcd438a9b6d3d59362a1f 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.323 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS03180 279b53fc511dcd438a9b6d3d59362a1f 86 SUPERFAMILY SSF46992 3 86 4.19E-31 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS03180 279b53fc511dcd438a9b6d3d59362a1f 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 1.7E-30 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS03180 279b53fc511dcd438a9b6d3d59362a1f 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 13 86 8.0E-22 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A6A12_RS13990 f298757a231ed30485dd6d35afdcc673 672 Gene3D G3DSA:1.10.486.10 377 553 1.5E-40 T 28-03-2018 A6A12_RS13990 f298757a231ed30485dd6d35afdcc673 672 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 1 670 40.498 T 28-03-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 A6A12_RS13990 f298757a231ed30485dd6d35afdcc673 672 Pfam PF00580 UvrD/REP helicase N-terminal domain 3 265 5.4E-76 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 A6A12_RS13990 f298757a231ed30485dd6d35afdcc673 672 SUPERFAMILY SSF52540 1 639 1.09E-161 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13990 f298757a231ed30485dd6d35afdcc673 672 Gene3D G3DSA:3.40.50.300 276 376 5.8E-21 T 28-03-2018 A6A12_RS13990 f298757a231ed30485dd6d35afdcc673 672 Pfam PF13361 UvrD-like helicase C-terminal domain 271 615 2.2E-73 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A6A12_RS13990 f298757a231ed30485dd6d35afdcc673 672 TIGRFAM TIGR01074 rep: ATP-dependent DNA helicase Rep 2 668 0.0 T 28-03-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 A6A12_RS13990 f298757a231ed30485dd6d35afdcc673 672 Gene3D G3DSA:3.40.50.300 136 275 3.3E-29 T 28-03-2018 A6A12_RS13990 f298757a231ed30485dd6d35afdcc673 672 Gene3D G3DSA:3.40.50.300 1 135 3.9E-23 T 28-03-2018 A6A12_RS13455 65d2caf2b7b1971aaa330dc41034f8fe 186 Gene3D G3DSA:2.160.10.10 1 170 8.5E-33 T 28-03-2018 A6A12_RS13455 65d2caf2b7b1971aaa330dc41034f8fe 186 SUPERFAMILY SSF51161 99 175 2.36E-30 T 28-03-2018 IPR011004 Trimeric LpxA-like A6A12_RS13455 65d2caf2b7b1971aaa330dc41034f8fe 186 SUPERFAMILY SSF51161 12 70 2.36E-30 T 28-03-2018 IPR011004 Trimeric LpxA-like A6A12_RS13455 65d2caf2b7b1971aaa330dc41034f8fe 186 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 35 69 1.2E-5 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS04600 ecabed16dfbf361dfb83cd2eac11ff26 181 SUPERFAMILY SSF110997 104 177 7.19E-14 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A6A12_RS04600 ecabed16dfbf361dfb83cd2eac11ff26 181 Gene3D G3DSA:3.30.70.1070 101 170 1.1E-8 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A6A12_RS04600 ecabed16dfbf361dfb83cd2eac11ff26 181 Pfam PF05036 Sporulation related domain 105 170 1.9E-10 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A6A12_RS01030 0961d3e9600794fa4cbadb718265efbd 241 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 30 221 2.1E-61 T 28-03-2018 IPR003744 Queuosine precursor transporter A6A12_RS01030 0961d3e9600794fa4cbadb718265efbd 241 Pfam PF02592 Putative vitamin uptake transporter 60 216 9.8E-38 T 28-03-2018 IPR003744 Queuosine precursor transporter A6A12_RS12010 b710ffa7b7ab57034a09e721e0fb5088 366 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 2 345 1.5E-117 T 28-03-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 A6A12_RS12010 b710ffa7b7ab57034a09e721e0fb5088 366 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 343 1.8E-70 T 28-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 A6A12_RS11130 ca8efd18e7f2006af8afc70e3391cec2 199 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 4 183 1.1E-59 T 28-03-2018 IPR006287 Protein DJ-1 A6A12_RS11130 ca8efd18e7f2006af8afc70e3391cec2 199 Pfam PF01965 DJ-1/PfpI family 3 169 1.0E-39 T 28-03-2018 IPR002818 DJ-1/PfpI A6A12_RS11130 ca8efd18e7f2006af8afc70e3391cec2 199 SUPERFAMILY SSF52317 3 188 3.85E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS11130 ca8efd18e7f2006af8afc70e3391cec2 199 Gene3D G3DSA:3.40.50.880 1 192 4.6E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS06610 bad48792e3eec07cdc21e989312c7591 72 Pfam PF11197 Protein of unknown function (DUF2835) 4 70 7.3E-29 T 28-03-2018 IPR021363 Protein of unknown function DUF2835 A6A12_RS07930 1e440215475826f659e256d2cc8af5d8 478 SUPERFAMILY SSF56954 107 447 1.83E-66 T 28-03-2018 A6A12_RS07930 1e440215475826f659e256d2cc8af5d8 478 SUPERFAMILY SSF56954 2 77 1.83E-66 T 28-03-2018 A6A12_RS07930 1e440215475826f659e256d2cc8af5d8 478 Pfam PF02321 Outer membrane efflux protein 267 447 1.2E-24 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A6A12_RS07930 1e440215475826f659e256d2cc8af5d8 478 Pfam PF02321 Outer membrane efflux protein 26 244 5.6E-21 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 A6A12_RS07930 1e440215475826f659e256d2cc8af5d8 478 Gene3D G3DSA:1.20.1600.10 16 452 2.5E-54 T 28-03-2018 A6A12_RS10160 2a5b3c1ae5e45dec26c3b431ac23b767 260 Pfam PF01311 Bacterial export proteins, family 1 13 243 5.2E-58 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A6A12_RS10160 2a5b3c1ae5e45dec26c3b431ac23b767 260 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 13 256 6.1E-76 T 28-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 A6A12_RS10160 2a5b3c1ae5e45dec26c3b431ac23b767 260 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 181 203 1.6E-16 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A6A12_RS10160 2a5b3c1ae5e45dec26c3b431ac23b767 260 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 21 42 1.6E-16 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A6A12_RS10160 2a5b3c1ae5e45dec26c3b431ac23b767 260 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 203 222 1.6E-16 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A6A12_RS10160 2a5b3c1ae5e45dec26c3b431ac23b767 260 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 1.6E-16 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 A6A12_RS01335 dccd30d76d56bec36382b4c2f5b4106d 262 SUPERFAMILY SSF54534 48 254 5.64E-62 T 28-03-2018 A6A12_RS01335 dccd30d76d56bec36382b4c2f5b4106d 262 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 38 158 3.0E-33 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 A6A12_RS01335 dccd30d76d56bec36382b4c2f5b4106d 262 Gene3D G3DSA:3.10.50.40 140 256 1.3E-45 T 28-03-2018 A6A12_RS01335 dccd30d76d56bec36382b4c2f5b4106d 262 Gene3D G3DSA:1.10.287.460 32 139 1.2E-26 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 A6A12_RS01335 dccd30d76d56bec36382b4c2f5b4106d 262 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 165 252 1.9E-30 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A6A12_RS00065 9afb69b98ab9f98c760ab0e065d6d275 82 Pfam PF01206 Sulfurtransferase TusA 12 79 4.7E-21 T 28-03-2018 IPR001455 TusA-like domain A6A12_RS00065 9afb69b98ab9f98c760ab0e065d6d275 82 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 12 36 - T 28-03-2018 IPR001455 TusA-like domain A6A12_RS00065 9afb69b98ab9f98c760ab0e065d6d275 82 SUPERFAMILY SSF64307 9 80 9.94E-24 T 28-03-2018 IPR001455 TusA-like domain A6A12_RS00065 9afb69b98ab9f98c760ab0e065d6d275 82 Hamap MF_00413 Sulfurtransferase TusA [tusA]. 3 81 27.998 T 28-03-2018 IPR022931 Sulfur carrier protein TusA GO:0002143|GO:0097163 A6A12_RS00065 9afb69b98ab9f98c760ab0e065d6d275 82 Gene3D G3DSA:3.30.110.40 6 81 2.9E-24 T 28-03-2018 IPR001455 TusA-like domain A6A12_RS11785 0980a3335be2f653c8f08282a6e9695d 243 Gene3D G3DSA:3.20.20.70 4 238 2.5E-106 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS11785 0980a3335be2f653c8f08282a6e9695d 243 SUPERFAMILY SSF63892 4 242 3.27E-102 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 A6A12_RS11785 0980a3335be2f653c8f08282a6e9695d 243 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 6 238 1.1E-105 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 A6A12_RS11785 0980a3335be2f653c8f08282a6e9695d 243 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 6 239 2.3E-100 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 A6A12_RS11785 0980a3335be2f653c8f08282a6e9695d 243 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 243 132.089 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 A6A12_RS09725 159f3d7d5fac6120256a3d9589d539e1 1028 Gene3D G3DSA:2.40.50.140 33 124 1.6E-30 T 28-03-2018 A6A12_RS09725 159f3d7d5fac6120256a3d9589d539e1 1028 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 424 2.1E-170 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 A6A12_RS09725 159f3d7d5fac6120256a3d9589d539e1 1028 Pfam PF00575 S1 RNA binding domain 37 118 9.4E-14 T 28-03-2018 IPR003029 S1 domain GO:0003676 A6A12_RS09725 159f3d7d5fac6120256a3d9589d539e1 1028 Pfam PF10150 Ribonuclease E/G family 121 390 1.3E-93 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 A6A12_RS09725 159f3d7d5fac6120256a3d9589d539e1 1028 Hamap MF_00970 Ribonuclease E [rne]. 1 1016 34.842 T 28-03-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 A6A12_RS09725 159f3d7d5fac6120256a3d9589d539e1 1028 SMART SM00316 37 119 2.6E-11 T 28-03-2018 IPR022967 RNA-binding domain, S1 A6A12_RS09725 159f3d7d5fac6120256a3d9589d539e1 1028 SUPERFAMILY SSF50249 40 124 2.14E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS12165 011289a010acece6b98e4730bf98dcae 95 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 95 3.8E-31 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A6A12_RS12165 011289a010acece6b98e4730bf98dcae 95 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 92 1.5E-26 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A6A12_RS12165 011289a010acece6b98e4730bf98dcae 95 SUPERFAMILY SSF69754 1 95 4.19E-33 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A6A12_RS12165 011289a010acece6b98e4730bf98dcae 95 Gene3D G3DSA:3.30.160.100 1 95 1.4E-31 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 A6A12_RS09310 d7f3e1a58c264bd0ad8822b00e454e83 782 Gene3D G3DSA:1.20.1640.10 193 405 5.2E-22 T 28-03-2018 A6A12_RS09310 d7f3e1a58c264bd0ad8822b00e454e83 782 Pfam PF03176 MMPL family 202 405 9.5E-12 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A6A12_RS09310 d7f3e1a58c264bd0ad8822b00e454e83 782 SUPERFAMILY SSF82866 193 403 2.09E-19 T 28-03-2018 A6A12_RS09310 d7f3e1a58c264bd0ad8822b00e454e83 782 SUPERFAMILY SSF82866 643 765 4.45E-22 T 28-03-2018 A6A12_RS09310 d7f3e1a58c264bd0ad8822b00e454e83 782 Gene3D G3DSA:1.20.1640.10 591 768 1.5E-19 T 28-03-2018 A6A12_RS12805 cfca4eda5a45d09e89707508b3990700 127 SUPERFAMILY SSF81343 1 127 1.59E-53 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A6A12_RS12805 cfca4eda5a45d09e89707508b3990700 127 Gene3D G3DSA:1.20.1300.10 2 127 4.8E-52 T 28-03-2018 A6A12_RS12805 cfca4eda5a45d09e89707508b3990700 127 PIRSF PIRSF000180 1 127 1.3E-57 T 28-03-2018 IPR003510 Fumarate reductase, subunit C GO:0016020 A6A12_RS12805 cfca4eda5a45d09e89707508b3990700 127 Hamap MF_00708 Fumarate reductase subunit C [frdC]. 1 127 27.302 T 28-03-2018 IPR003510 Fumarate reductase, subunit C GO:0016020 A6A12_RS12805 cfca4eda5a45d09e89707508b3990700 127 ProDom PD015900 FUMARATE MEMBRANE REDUCTASE C SUBUNIT TRANSMEMBRANE INNER HYDROPHOBIC REDUCTASE POLYPEPTIDE 7 127 1.0E-47 T 28-03-2018 IPR003510 Fumarate reductase, subunit C GO:0016020 A6A12_RS12805 cfca4eda5a45d09e89707508b3990700 127 Pfam PF02300 Fumarate reductase subunit C 2 127 5.8E-50 T 28-03-2018 IPR003510 Fumarate reductase, subunit C GO:0016020 A6A12_RS02235 9b6b3e896e33ea49ed9bf676e64663c4 128 Gene3D G3DSA:1.10.10.10 36 108 4.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS02235 9b6b3e896e33ea49ed9bf676e64663c4 128 SUPERFAMILY SSF46785 53 106 3.57E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS12320 b9a3cb12e0f1f18fc91d0109a3d1e97a 195 Pfam PF09335 SNARE associated Golgi protein 44 151 2.1E-12 T 28-03-2018 IPR032816 SNARE associated Golgi protein A6A12_RS12035 838de791d205bacb4f5856e37a1f81cd 245 Pfam PF00849 RNA pseudouridylate synthase 23 169 9.2E-29 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS12035 838de791d205bacb4f5856e37a1f81cd 245 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 60 74 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS12035 838de791d205bacb4f5856e37a1f81cd 245 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 9 206 3.8E-59 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS12035 838de791d205bacb4f5856e37a1f81cd 245 Gene3D G3DSA:3.30.2350.10 13 234 2.7E-59 T 28-03-2018 A6A12_RS12035 838de791d205bacb4f5856e37a1f81cd 245 SUPERFAMILY SSF55120 7 214 2.88E-63 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS01125 afbdb5b419feff425f136405c9dfcfb5 370 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 66 370 1.1E-146 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A6A12_RS01125 afbdb5b419feff425f136405c9dfcfb5 370 Hamap MF_00215 Pantothenate kinase [coaA]. 1 370 167.271 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 A6A12_RS01125 afbdb5b419feff425f136405c9dfcfb5 370 Gene3D G3DSA:3.40.50.300 64 370 1.3E-55 T 28-03-2018 A6A12_RS01125 afbdb5b419feff425f136405c9dfcfb5 370 SUPERFAMILY SSF52540 66 370 2.43E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01125 afbdb5b419feff425f136405c9dfcfb5 370 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 145 302 2.7E-13 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 A6A12_RS09410 7e4e572cc14c2762ae2b279d3fb61352 147 Pfam PF01037 Lrp/AsnC ligand binding domain 68 140 2.4E-15 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A6A12_RS09410 7e4e572cc14c2762ae2b279d3fb61352 147 Gene3D G3DSA:3.30.70.920 53 147 2.9E-18 T 28-03-2018 A6A12_RS09410 7e4e572cc14c2762ae2b279d3fb61352 147 Gene3D G3DSA:1.10.10.10 1 52 5.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09410 7e4e572cc14c2762ae2b279d3fb61352 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 3.3E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A6A12_RS09410 7e4e572cc14c2762ae2b279d3fb61352 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 3.3E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A6A12_RS09410 7e4e572cc14c2762ae2b279d3fb61352 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 3.3E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A6A12_RS09410 7e4e572cc14c2762ae2b279d3fb61352 147 SMART SM00344 1 110 2.2E-32 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A6A12_RS09410 7e4e572cc14c2762ae2b279d3fb61352 147 SUPERFAMILY SSF46785 1 59 9.11E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09410 7e4e572cc14c2762ae2b279d3fb61352 147 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 1.9E-16 T 28-03-2018 A6A12_RS09410 7e4e572cc14c2762ae2b279d3fb61352 147 SUPERFAMILY SSF54909 63 146 4.29E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel A6A12_RS03940 aed9182d36d04febbb5e0ac8fcc37881 280 Pfam PF00756 Putative esterase 23 272 5.1E-63 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A6A12_RS03940 aed9182d36d04febbb5e0ac8fcc37881 280 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 5 278 6.0E-124 T 28-03-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 A6A12_RS03940 aed9182d36d04febbb5e0ac8fcc37881 280 SUPERFAMILY SSF53474 3 279 1.09E-92 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS03940 aed9182d36d04febbb5e0ac8fcc37881 280 Gene3D G3DSA:3.40.50.1820 1 279 4.3E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS06135 36332637321958570324070321c9566f 962 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 780 801 - T 28-03-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 A6A12_RS06135 36332637321958570324070321c9566f 962 Pfam PF00202 Aminotransferase class-III 51 464 1.4E-91 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A6A12_RS06135 36332637321958570324070321c9566f 962 Gene3D G3DSA:1.20.1650.10 478 560 3.2E-34 T 28-03-2018 A6A12_RS06135 36332637321958570324070321c9566f 962 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 531 892 2.1E-63 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A6A12_RS06135 36332637321958570324070321c9566f 962 Gene3D G3DSA:3.40.640.10 571 846 3.9E-53 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS06135 36332637321958570324070321c9566f 962 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 35 465 9.8E-157 T 28-03-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 A6A12_RS06135 36332637321958570324070321c9566f 962 SUPERFAMILY SSF53383 41 464 1.95E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS06135 36332637321958570324070321c9566f 962 Gene3D G3DSA:3.90.1150.10 342 468 8.5E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS06135 36332637321958570324070321c9566f 962 SUPERFAMILY SSF53383 509 959 7.58E-114 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS06135 36332637321958570324070321c9566f 962 Gene3D G3DSA:3.90.1150.10 847 960 5.8E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS06135 36332637321958570324070321c9566f 962 Gene3D G3DSA:3.40.640.10 78 341 3.9E-68 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS14000 85877f7bd8d6350b4607dee208b5988b 368 SUPERFAMILY SSF111369 58 273 8.11E-40 T 28-03-2018 A6A12_RS14000 85877f7bd8d6350b4607dee208b5988b 368 Pfam PF00529 HlyD membrane-fusion protein of T1SS 65 339 2.2E-7 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A6A12_RS14000 85877f7bd8d6350b4607dee208b5988b 368 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 353 5.0E-73 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 A6A12_RS14000 85877f7bd8d6350b4607dee208b5988b 368 Gene3D G3DSA:2.40.50.100 26 100 4.6E-5 T 28-03-2018 A6A12_RS14000 85877f7bd8d6350b4607dee208b5988b 368 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 64 269 2.3E-27 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain A6A12_RS14000 85877f7bd8d6350b4607dee208b5988b 368 Gene3D G3DSA:1.20.1600.10 101 292 2.7E-27 T 28-03-2018 A6A12_RS09755 025919b15e97f753cb52c73d357ae847 398 Pfam PF01627 Hpt domain 308 387 4.1E-11 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS09755 025919b15e97f753cb52c73d357ae847 398 Gene3D G3DSA:1.20.120.160 163 398 5.2E-21 T 28-03-2018 A6A12_RS09755 025919b15e97f753cb52c73d357ae847 398 SUPERFAMILY SSF47226 286 395 9.94E-16 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 A6A12_RS00035 a9faadeb7913f928d87c527915fd0359 145 Pfam PF00011 Hsp20/alpha crystallin family 43 137 1.9E-21 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain A6A12_RS00035 a9faadeb7913f928d87c527915fd0359 145 Gene3D G3DSA:2.60.40.790 11 137 7.6E-25 T 28-03-2018 IPR008978 HSP20-like chaperone A6A12_RS00035 a9faadeb7913f928d87c527915fd0359 145 SUPERFAMILY SSF49764 6 138 5.58E-25 T 28-03-2018 IPR008978 HSP20-like chaperone A6A12_RS09955 eab4492865233cf8783680aabb7059d1 142 Pfam PF01230 HIT domain 11 99 3.0E-18 T 28-03-2018 IPR001310 Histidine triad (HIT) protein A6A12_RS09955 eab4492865233cf8783680aabb7059d1 142 Gene3D G3DSA:3.30.428.10 1 135 1.5E-21 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 A6A12_RS09955 eab4492865233cf8783680aabb7059d1 142 SUPERFAMILY SSF54197 3 133 4.89E-34 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 A6A12_RS09955 eab4492865233cf8783680aabb7059d1 142 PIRSF PIRSF000714 2 139 2.4E-52 T 28-03-2018 IPR026026 Histidine triad hydrolase, Hint-type A6A12_RS02580 0a550d5a0490be8adb52e0f726db86f9 65 SUPERFAMILY SSF57716 5 63 4.28E-21 T 28-03-2018 A6A12_RS02580 0a550d5a0490be8adb52e0f726db86f9 65 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 4 60 18.254 T 28-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 A6A12_RS02580 0a550d5a0490be8adb52e0f726db86f9 65 Gene3D G3DSA:3.30.50.10 3 61 7.7E-25 T 28-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 A6A12_RS02580 0a550d5a0490be8adb52e0f726db86f9 65 Pfam PF03884 DNA gyrase inhibitor YacG 8 58 1.4E-24 T 28-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 A6A12_RS03420 eeaa974d650b4f40b71c228a93f848e3 272 Pfam PF00005 ABC transporter 41 197 2.9E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS03420 eeaa974d650b4f40b71c228a93f848e3 272 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 26 272 8.8E-122 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 A6A12_RS03420 eeaa974d650b4f40b71c228a93f848e3 272 Gene3D G3DSA:3.40.50.300 13 270 2.0E-61 T 28-03-2018 A6A12_RS03420 eeaa974d650b4f40b71c228a93f848e3 272 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS03420 eeaa974d650b4f40b71c228a93f848e3 272 SMART SM00382 50 253 1.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS03420 eeaa974d650b4f40b71c228a93f848e3 272 SUPERFAMILY SSF52540 23 258 2.01E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS08570 c4a18330a3227e4e864b4db2ced7da0c 322 Pfam PF13730 Helix-turn-helix domain 19 66 2.8E-9 T 28-03-2018 A6A12_RS06015 befa1406a6a410cb2a2f8c81c811eb8a 83 Pfam PF06945 Protein of unknown function (DUF1289) 11 56 7.6E-19 T 28-03-2018 IPR010710 Protein of unknown function DUF1289 A6A12_RS00590 97028cf9a9336203a9f302c32e22f53c 207 SUPERFAMILY SSF46785 3 69 8.84E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS00590 97028cf9a9336203a9f302c32e22f53c 207 Pfam PF00717 Peptidase S24-like 119 185 8.2E-16 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A6A12_RS00590 97028cf9a9336203a9f302c32e22f53c 207 Pfam PF01726 LexA DNA binding domain 1 65 3.4E-29 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 A6A12_RS00590 97028cf9a9336203a9f302c32e22f53c 207 Gene3D G3DSA:2.10.109.10 85 204 7.2E-27 T 28-03-2018 A6A12_RS00590 97028cf9a9336203a9f302c32e22f53c 207 Hamap MF_00015 LexA repressor [lexA]. 3 204 32.031 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A6A12_RS00590 97028cf9a9336203a9f302c32e22f53c 207 Gene3D G3DSA:1.10.10.10 1 70 3.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS00590 97028cf9a9336203a9f302c32e22f53c 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 116 126 4.9E-13 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A6A12_RS00590 97028cf9a9336203a9f302c32e22f53c 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 127 138 4.9E-13 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A6A12_RS00590 97028cf9a9336203a9f302c32e22f53c 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 155 167 4.9E-13 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 A6A12_RS00590 97028cf9a9336203a9f302c32e22f53c 207 SUPERFAMILY SSF51306 81 203 1.46E-37 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A6A12_RS00590 97028cf9a9336203a9f302c32e22f53c 207 TIGRFAM TIGR00498 lexA: repressor LexA 1 204 6.2E-81 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 A6A12_RS03530 faebe738461791341b26b91fc345bb7a 64 SUPERFAMILY SSF140319 1 62 7.06E-28 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 A6A12_RS03530 faebe738461791341b26b91fc345bb7a 64 PIRSF PIRSF039003 1 64 4.2E-34 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 A6A12_RS03530 faebe738461791341b26b91fc345bb7a 64 Gene3D G3DSA:1.10.10.600 1 62 8.9E-34 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 A6A12_RS03530 faebe738461791341b26b91fc345bb7a 64 Pfam PF04384 Iron-sulphur cluster assembly 1 63 2.3E-33 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 A6A12_RS03530 faebe738461791341b26b91fc345bb7a 64 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 2 64 1.0E-34 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 A6A12_RS01940 09055b3f5c7c89239d5e97a13c542f37 142 SUPERFAMILY SSF53098 4 137 8.04E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS01940 09055b3f5c7c89239d5e97a13c542f37 142 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 140 23.227 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A6A12_RS01940 09055b3f5c7c89239d5e97a13c542f37 142 SMART SM00732 4 105 2.7E-34 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 A6A12_RS01940 09055b3f5c7c89239d5e97a13c542f37 142 Pfam PF03652 Holliday junction resolvase 5 137 7.3E-35 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A6A12_RS01940 09055b3f5c7c89239d5e97a13c542f37 142 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 7 137 8.9E-46 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 A6A12_RS01940 09055b3f5c7c89239d5e97a13c542f37 142 Gene3D G3DSA:3.30.420.140 2 140 3.2E-36 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 A6A12_RS03865 f25b5ea5db6dc92e5772d8936a8cd24f 143 SUPERFAMILY SSF55961 1 142 2.96E-32 T 28-03-2018 A6A12_RS03865 f25b5ea5db6dc92e5772d8936a8cd24f 143 Gene3D G3DSA:3.30.530.20 1 143 4.4E-28 T 28-03-2018 IPR023393 START-like domain A6A12_RS03865 f25b5ea5db6dc92e5772d8936a8cd24f 143 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 135 3.6E-29 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 A6A12_RS03375 360a113ad4b217dbf7305f860838e1b2 466 Pfam PF01136 Peptidase family U32 80 355 1.9E-96 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A6A12_RS03375 360a113ad4b217dbf7305f860838e1b2 466 Gene3D G3DSA:3.20.20.70 7 177 2.4E-4 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS03375 360a113ad4b217dbf7305f860838e1b2 466 ProSitePatterns PS01276 Peptidase family U32 signature. 167 185 - T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 A6A12_RS03375 360a113ad4b217dbf7305f860838e1b2 466 Pfam PF16325 Peptidase family U32 C-terminal domain 371 444 1.6E-20 T 28-03-2018 IPR032525 Peptidase family U32, C-terminal A6A12_RS04620 8bd44b252b4c4cfc8f1302397d2feb54 219 SUPERFAMILY SSF53098 10 208 1.01E-55 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS04620 8bd44b252b4c4cfc8f1302397d2feb54 219 Pfam PF00929 Exonuclease 20 195 5.9E-44 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS04620 8bd44b252b4c4cfc8f1302397d2feb54 219 SMART SM00479 18 204 6.4E-30 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS04620 8bd44b252b4c4cfc8f1302397d2feb54 219 Hamap MF_00157 Ribonuclease T [rnt]. 1 219 115.878 T 28-03-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 A6A12_RS04620 8bd44b252b4c4cfc8f1302397d2feb54 219 Gene3D G3DSA:3.30.420.10 9 215 1.7E-30 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS04620 8bd44b252b4c4cfc8f1302397d2feb54 219 TIGRFAM TIGR01298 RNaseT: ribonuclease T 10 209 3.0E-99 T 28-03-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 A6A12_RS01440 6a61100b330bb3677aa017b463afc924 154 Pfam PF01475 Ferric uptake regulator family 22 140 5.6E-21 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A6A12_RS01440 6a61100b330bb3677aa017b463afc924 154 Gene3D G3DSA:1.10.10.10 5 92 1.9E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS01440 6a61100b330bb3677aa017b463afc924 154 SUPERFAMILY SSF46785 14 146 7.37E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS06960 ef058e41de73d55b258234d7890be6ca 337 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 82 333 8.0E-40 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A6A12_RS06960 ef058e41de73d55b258234d7890be6ca 337 Gene3D G3DSA:3.90.850.10 26 325 7.8E-53 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A6A12_RS06960 ef058e41de73d55b258234d7890be6ca 337 SUPERFAMILY SSF56529 77 334 1.7E-55 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 A6A12_RS12365 5b224a35eb85b66e61ece2109bb4686a 202 Gene3D G3DSA:3.10.350.10 116 172 0.0011 T 28-03-2018 A6A12_RS12365 5b224a35eb85b66e61ece2109bb4686a 202 Pfam PF08525 Opacity-associated protein A N-terminal motif 51 78 7.7E-7 T 28-03-2018 IPR013731 Opacity-associated protein A, N-terminal A6A12_RS12365 5b224a35eb85b66e61ece2109bb4686a 202 Pfam PF04225 Opacity-associated protein A LysM-like domain 119 202 6.2E-38 T 28-03-2018 IPR007340 Opacity-associated protein A A6A12_RS06275 4141404a1d5abd5cd8de001f991129da 319 Hamap MF_00397 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase [citG]. 1 319 149.068 T 28-03-2018 IPR017551 Triphosphoribosyl-dephospho-CoA synthase CitG GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 A6A12_RS06275 4141404a1d5abd5cd8de001f991129da 319 TIGRFAM TIGR03125 citrate_citG: triphosphoribosyl-dephospho-CoA synthase CitG 34 304 9.4E-103 T 28-03-2018 IPR017551 Triphosphoribosyl-dephospho-CoA synthase CitG GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 A6A12_RS06275 4141404a1d5abd5cd8de001f991129da 319 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 35 303 4.1E-80 T 28-03-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 A6A12_RS11605 fc6eeed47c3938dbd62f3757b61a6c15 211 Gene3D G3DSA:1.20.1050.10 89 209 3.7E-14 T 28-03-2018 A6A12_RS11605 fc6eeed47c3938dbd62f3757b61a6c15 211 SUPERFAMILY SSF47616 82 208 8.67E-23 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like A6A12_RS11605 fc6eeed47c3938dbd62f3757b61a6c15 211 Pfam PF00043 Glutathione S-transferase, C-terminal domain 117 194 9.1E-8 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal A6A12_RS11605 fc6eeed47c3938dbd62f3757b61a6c15 211 Gene3D G3DSA:3.40.30.10 1 88 3.8E-23 T 28-03-2018 A6A12_RS11605 fc6eeed47c3938dbd62f3757b61a6c15 211 Pfam PF13417 Glutathione S-transferase, N-terminal domain 13 87 4.2E-17 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 A6A12_RS11605 fc6eeed47c3938dbd62f3757b61a6c15 211 SUPERFAMILY SSF52833 11 110 3.09E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS00245 a3bf5a8b3ec14443272c86aa2dc0b775 481 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 85 464 3.4E-113 T 28-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 A6A12_RS00245 a3bf5a8b3ec14443272c86aa2dc0b775 481 PIRSF PIRSF006247 1 481 3.4E-165 T 28-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 A6A12_RS00245 a3bf5a8b3ec14443272c86aa2dc0b775 481 Pfam PF02386 Cation transport protein 44 475 1.5E-50 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A6A12_RS08300 600f1f9aada32a13dcf6090ad76feeb1 84 Pfam PF07383 Protein of unknown function (DUF1496) 29 80 2.8E-23 T 28-03-2018 IPR009971 Protein of unknown function DUF1496 A6A12_RS02725 605d647d76e328cf522668f2f4717c5c 148 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 25 147 29.821 T 28-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 A6A12_RS02725 605d647d76e328cf522668f2f4717c5c 148 SUPERFAMILY SSF57716 108 146 5.99E-10 T 28-03-2018 A6A12_RS02725 605d647d76e328cf522668f2f4717c5c 148 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 108 140 3.2E-10 T 28-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 A6A12_RS02725 605d647d76e328cf522668f2f4717c5c 148 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 29 137 5.4E-51 T 28-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 A6A12_RS02725 605d647d76e328cf522668f2f4717c5c 148 PRINTS PR00618 DksA/TraR zinc finger signature 111 122 8.9E-5 T 28-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria A6A12_RS02725 605d647d76e328cf522668f2f4717c5c 148 PRINTS PR00618 DksA/TraR zinc finger signature 123 135 8.9E-5 T 28-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria A6A12_RS02725 605d647d76e328cf522668f2f4717c5c 148 SUPERFAMILY SSF109635 9 107 8.63E-37 T 28-03-2018 A6A12_RS02725 605d647d76e328cf522668f2f4717c5c 148 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 111 135 - T 28-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site A6A12_RS05405 7b0cbd433f17979947c94835defac1e4 396 SUPERFAMILY SSF53686 5 388 1.57E-140 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A6A12_RS05405 7b0cbd433f17979947c94835defac1e4 396 Gene3D G3DSA:3.40.50.1100 196 396 2.1E-38 T 28-03-2018 A6A12_RS05405 7b0cbd433f17979947c94835defac1e4 396 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 6 389 6.0E-195 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A6A12_RS05405 7b0cbd433f17979947c94835defac1e4 396 PIRSF PIRSF001413 1 395 4.8E-167 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A6A12_RS05405 7b0cbd433f17979947c94835defac1e4 396 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 51 376 7.8E-49 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A6A12_RS05405 7b0cbd433f17979947c94835defac1e4 396 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 79 93 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A6A12_RS05405 7b0cbd433f17979947c94835defac1e4 396 Gene3D G3DSA:3.40.50.1100 8 195 7.9E-46 T 28-03-2018 A6A12_RS05405 7b0cbd433f17979947c94835defac1e4 396 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 390 49.733 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A6A12_RS01600 6e53a638c03602fdd7e7406ed6a7606b 371 SMART SM00028 214 247 330.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS01600 6e53a638c03602fdd7e7406ed6a7606b 371 SMART SM00028 180 213 60.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS01600 6e53a638c03602fdd7e7406ed6a7606b 371 SMART SM00028 280 313 13.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS01600 6e53a638c03602fdd7e7406ed6a7606b 371 SMART SM00028 314 347 43.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A6A12_RS01600 6e53a638c03602fdd7e7406ed6a7606b 371 Gene3D G3DSA:1.25.40.10 272 369 8.2E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS01600 6e53a638c03602fdd7e7406ed6a7606b 371 Gene3D G3DSA:1.25.40.10 157 271 3.9E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS01600 6e53a638c03602fdd7e7406ed6a7606b 371 SUPERFAMILY SSF81901 187 342 1.2E-12 T 28-03-2018 A6A12_RS11755 138ef1c2421683bf3812e57d9fe27a64 546 Pfam PF06418 CTP synthase N-terminus 5 265 3.7E-125 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A6A12_RS11755 138ef1c2421683bf3812e57d9fe27a64 546 TIGRFAM TIGR00337 PyrG: CTP synthase 2 535 8.5E-261 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A6A12_RS11755 138ef1c2421683bf3812e57d9fe27a64 546 SUPERFAMILY SSF52317 289 539 1.49E-87 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS11755 138ef1c2421683bf3812e57d9fe27a64 546 Hamap MF_01227 CTP synthase [pyrG]. 3 540 51.291 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A6A12_RS11755 138ef1c2421683bf3812e57d9fe27a64 546 Gene3D G3DSA:3.40.50.300 1 285 6.8E-128 T 28-03-2018 A6A12_RS11755 138ef1c2421683bf3812e57d9fe27a64 546 SUPERFAMILY SSF52540 3 269 1.51E-121 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS11755 138ef1c2421683bf3812e57d9fe27a64 546 Gene3D G3DSA:3.40.50.880 286 542 4.3E-74 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like A6A12_RS11755 138ef1c2421683bf3812e57d9fe27a64 546 Pfam PF00117 Glutamine amidotransferase class-I 301 535 7.3E-63 T 28-03-2018 IPR017926 Glutamine amidotransferase A6A12_RS03175 20cd58216bf387ae5afae2e168256768 97 Gene3D G3DSA:1.10.10.10 1 90 2.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03175 20cd58216bf387ae5afae2e168256768 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 17 32 9.0E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A6A12_RS03175 20cd58216bf387ae5afae2e168256768 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 47 9.0E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A6A12_RS03175 20cd58216bf387ae5afae2e168256768 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 9.0E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A6A12_RS03175 20cd58216bf387ae5afae2e168256768 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 9.0E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A6A12_RS03175 20cd58216bf387ae5afae2e168256768 97 SMART SM00418 15 93 4.0E-29 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A6A12_RS03175 20cd58216bf387ae5afae2e168256768 97 SUPERFAMILY SSF46785 9 96 4.79E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS03175 20cd58216bf387ae5afae2e168256768 97 Pfam PF01022 Bacterial regulatory protein, arsR family 23 67 5.0E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A6A12_RS09045 283237f9df59ce90d0447750b9b9cee5 256 Pfam PF10972 Peptidoglycan-binding protein, CsiV 6 254 3.3E-64 T 28-03-2018 IPR021241 Peptidoglycan-binding protein, CsiV A6A12_RS05635 01fa46f1b1e982d189b0a108f6b1ffec 298 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 155 176 - T 28-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 A6A12_RS05635 01fa46f1b1e982d189b0a108f6b1ffec 298 Gene3D G3DSA:3.40.190.10 112 191 1.9E-29 T 28-03-2018 A6A12_RS05635 01fa46f1b1e982d189b0a108f6b1ffec 298 SUPERFAMILY SSF54913 225 297 1.22E-20 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A6A12_RS05635 01fa46f1b1e982d189b0a108f6b1ffec 298 Pfam PF01634 ATP phosphoribosyltransferase 53 218 2.2E-46 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A6A12_RS05635 01fa46f1b1e982d189b0a108f6b1ffec 298 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 200 297 2.0E-30 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A6A12_RS05635 01fa46f1b1e982d189b0a108f6b1ffec 298 Pfam PF08029 HisG, C-terminal domain 222 295 1.6E-23 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A6A12_RS05635 01fa46f1b1e982d189b0a108f6b1ffec 298 SUPERFAMILY SSF53850 5 222 1.18E-66 T 28-03-2018 A6A12_RS05635 01fa46f1b1e982d189b0a108f6b1ffec 298 Gene3D G3DSA:3.30.70.120 226 297 2.7E-23 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A6A12_RS05635 01fa46f1b1e982d189b0a108f6b1ffec 298 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 5 298 35.224 T 28-03-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 A6A12_RS05635 01fa46f1b1e982d189b0a108f6b1ffec 298 Gene3D G3DSA:3.40.190.10 1 111 2.3E-26 T 28-03-2018 A6A12_RS05635 01fa46f1b1e982d189b0a108f6b1ffec 298 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 6 196 7.9E-55 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 A6A12_RS05565 953f152a75e912d59cf4e4da94d5a14f 316 Gene3D G3DSA:1.10.3210.10 22 276 8.6E-28 T 28-03-2018 A6A12_RS05565 953f152a75e912d59cf4e4da94d5a14f 316 SUPERFAMILY SSF109604 42 310 2.23E-37 T 28-03-2018 A6A12_RS05565 953f152a75e912d59cf4e4da94d5a14f 316 Pfam PF08668 HDOD domain 49 245 3.4E-36 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD A6A12_RS14395 8bab989b49af91e64c022116bd0cec2d 257 PIRSF PIRSF009320 2 85 1.0E-13 T 28-03-2018 A6A12_RS14395 8bab989b49af91e64c022116bd0cec2d 257 PIRSF PIRSF009320 86 252 6.2E-9 T 28-03-2018 A6A12_RS14395 8bab989b49af91e64c022116bd0cec2d 257 SUPERFAMILY SSF52540 2 253 9.69E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS14395 8bab989b49af91e64c022116bd0cec2d 257 Pfam PF13614 AAA domain 2 178 9.0E-63 T 28-03-2018 IPR025669 AAA domain A6A12_RS14395 8bab989b49af91e64c022116bd0cec2d 257 Gene3D G3DSA:3.40.50.300 1 255 9.2E-60 T 28-03-2018 A6A12_RS12640 5f03fcebecac43907f4d1db4d42d5dcc 871 SUPERFAMILY SSF74853 30 133 9.42E-6 T 28-03-2018 IPR001322 Lamin Tail Domain A6A12_RS12640 5f03fcebecac43907f4d1db4d42d5dcc 871 Pfam PF00932 Lamin Tail Domain 25 135 1.4E-13 T 28-03-2018 IPR001322 Lamin Tail Domain A6A12_RS12640 5f03fcebecac43907f4d1db4d42d5dcc 871 Gene3D G3DSA:2.40.50.200 193 302 4.0E-5 T 28-03-2018 A6A12_RS12640 5f03fcebecac43907f4d1db4d42d5dcc 871 Gene3D G3DSA:2.60.40.1260 10 136 1.1E-10 T 28-03-2018 IPR001322 Lamin Tail Domain A6A12_RS12640 5f03fcebecac43907f4d1db4d42d5dcc 871 SUPERFAMILY SSF56219 475 847 1.87E-28 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A6A12_RS12640 5f03fcebecac43907f4d1db4d42d5dcc 871 Gene3D G3DSA:3.60.10.10 477 847 5.9E-29 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase A6A12_RS04695 951a4d9f4f9d6416bbc762f042d24297 415 Pfam PF14319 Transposase zinc-binding domain 30 135 5.7E-28 T 28-03-2018 IPR026889 Transposase zinc-binding domain A6A12_RS04695 951a4d9f4f9d6416bbc762f042d24297 415 Pfam PF04986 Putative transposase 158 336 2.4E-51 T 28-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 A6A12_RS06480 951a4d9f4f9d6416bbc762f042d24297 415 Pfam PF14319 Transposase zinc-binding domain 30 135 5.7E-28 T 28-03-2018 IPR026889 Transposase zinc-binding domain A6A12_RS06480 951a4d9f4f9d6416bbc762f042d24297 415 Pfam PF04986 Putative transposase 158 336 2.4E-51 T 28-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 A6A12_RS07850 6d046c6fc1d5cf9dcf3b1e1806a6b623 98 Pfam PF05488 PAAR motif 24 88 9.5E-22 T 28-03-2018 IPR008727 PAAR motif A6A12_RS04250 895628264da0805b96b048eb1ceb9615 440 Gene3D G3DSA:3.40.50.980 110 277 3.6E-8 T 28-03-2018 A6A12_RS04250 895628264da0805b96b048eb1ceb9615 440 SUPERFAMILY SSF56801 115 286 4.84E-8 T 28-03-2018 A6A12_RS00535 1e1ecb5abc8ab3eadd88d1f689993899 199 Pfam PF03602 Conserved hypothetical protein 95 19 194 2.4E-61 T 28-03-2018 A6A12_RS00535 1e1ecb5abc8ab3eadd88d1f689993899 199 PIRSF PIRSF004553 18 198 1.7E-56 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 A6A12_RS00535 1e1ecb5abc8ab3eadd88d1f689993899 199 Gene3D G3DSA:3.40.50.150 5 199 4.5E-38 T 28-03-2018 A6A12_RS00535 1e1ecb5abc8ab3eadd88d1f689993899 199 SUPERFAMILY SSF53335 19 195 2.43E-53 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS00535 1e1ecb5abc8ab3eadd88d1f689993899 199 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 16 196 2.2E-62 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 A6A12_RS01280 cd6ea22ea1e710c93e9dc3bf12eccfe5 154 SUPERFAMILY SSF52540 28 127 5.09E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01280 cd6ea22ea1e710c93e9dc3bf12eccfe5 154 Gene3D G3DSA:3.40.50.300 1 153 2.2E-51 T 28-03-2018 A6A12_RS01280 cd6ea22ea1e710c93e9dc3bf12eccfe5 154 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 8 139 1.6E-50 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A6A12_RS01280 cd6ea22ea1e710c93e9dc3bf12eccfe5 154 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 134 9.1E-42 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 A6A12_RS08075 fcbf4a874003f0a0d91890fa828a2059 227 SUPERFAMILY SSF51735 4 214 5.51E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS08075 fcbf4a874003f0a0d91890fa828a2059 227 Pfam PF08732 HIM1 75 166 3.9E-11 T 28-03-2018 IPR014843 Protein Him1/Fmp52 A6A12_RS08075 fcbf4a874003f0a0d91890fa828a2059 227 Gene3D G3DSA:3.40.50.720 2 225 4.4E-17 T 28-03-2018 A6A12_RS09080 78a9522c29fa6aabc86f96b12a61865d 463 Gene3D G3DSA:1.25.40.10 27 184 0.0065 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS09080 78a9522c29fa6aabc86f96b12a61865d 463 Gene3D G3DSA:1.25.40.10 187 300 1.1E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS09080 78a9522c29fa6aabc86f96b12a61865d 463 SUPERFAMILY SSF48452 128 263 2.53E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS09290 89ffe2c90d2c89c0352ae2151ee6c2d4 576 SUPERFAMILY SSF53448 10 242 3.0E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS09290 89ffe2c90d2c89c0352ae2151ee6c2d4 576 Pfam PF00535 Glycosyl transferase family 2 11 130 3.0E-22 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A6A12_RS09290 89ffe2c90d2c89c0352ae2151ee6c2d4 576 Gene3D G3DSA:3.90.550.10 9 340 1.8E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS09290 89ffe2c90d2c89c0352ae2151ee6c2d4 576 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 350 564 2.1E-12 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 A6A12_RS03980 f48c1cafd5d07c71608b74f6c29ae10d 63 Pfam PF14056 Domain of unknown function (DUF4250) 8 62 5.7E-21 T 28-03-2018 IPR025346 Protein of unknown function DUF4250 A6A12_RS09910 604cd92573c95198cc98b13c0819746b 122 Gene3D G3DSA:3.40.50.2300 1 122 2.6E-36 T 28-03-2018 A6A12_RS09910 604cd92573c95198cc98b13c0819746b 122 SMART SM00448 1 115 1.8E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS09910 604cd92573c95198cc98b13c0819746b 122 Pfam PF00072 Response regulator receiver domain 3 115 1.5E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS09910 604cd92573c95198cc98b13c0819746b 122 SUPERFAMILY SSF52172 1 120 3.98E-36 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS11080 f218974c12005a5f6d8d57d93515570a 115 Pfam PF01722 BolA-like protein 23 96 1.5E-31 T 28-03-2018 IPR002634 BolA protein A6A12_RS11080 f218974c12005a5f6d8d57d93515570a 115 SUPERFAMILY SSF82657 10 99 8.63E-33 T 28-03-2018 IPR002634 BolA protein A6A12_RS11080 f218974c12005a5f6d8d57d93515570a 115 Gene3D G3DSA:3.30.300.90 11 103 1.9E-30 T 28-03-2018 A6A12_RS11080 f218974c12005a5f6d8d57d93515570a 115 PIRSF PIRSF003113 2 112 5.7E-39 T 28-03-2018 IPR002634 BolA protein A6A12_RS04645 4835c293221863259c224b086bb1dc6d 212 PIRSF PIRSF006091 1 204 7.2E-80 T 28-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 A6A12_RS04645 4835c293221863259c224b086bb1dc6d 212 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 2 194 26.015 T 28-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 A6A12_RS04645 4835c293221863259c224b086bb1dc6d 212 SMART SM00900 100 192 1.4E-33 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 A6A12_RS04645 4835c293221863259c224b086bb1dc6d 212 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 9 193 2.0E-65 T 28-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 A6A12_RS04645 4835c293221863259c224b086bb1dc6d 212 Pfam PF04205 FMN-binding domain 100 188 6.8E-21 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 A6A12_RS01640 d08e5b388a6c891ef786a70a9e857c94 256 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 22 2.1E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS01640 d08e5b388a6c891ef786a70a9e857c94 256 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 2 22 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS01640 d08e5b388a6c891ef786a70a9e857c94 256 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 22 7.9E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS02515 9b37d184b169a8d8c4f39cbf1f6d7123 376 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 20 374 4.7E-161 T 28-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 A6A12_RS02515 9b37d184b169a8d8c4f39cbf1f6d7123 376 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 19 370 1.3E-173 T 28-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 A6A12_RS02515 9b37d184b169a8d8c4f39cbf1f6d7123 376 PIRSF PIRSF015658 1 376 2.2E-180 T 28-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 A6A12_RS07310 a65c0657ace9bf60c309e6321139ad59 157 Pfam PF11163 Protein of unknown function (DUF2947) 3 154 1.4E-71 T 28-03-2018 IPR021334 Protein of unknown function DUF2947 A6A12_RS11900 ec25edd44a14bee6be82706a972dc7df 409 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 154 181 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A6A12_RS11900 ec25edd44a14bee6be82706a972dc7df 409 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 294 1.3E-53 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A6A12_RS11900 ec25edd44a14bee6be82706a972dc7df 409 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 13 326 2.5E-37 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 A6A12_RS11900 ec25edd44a14bee6be82706a972dc7df 409 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 200 222 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A6A12_RS11900 ec25edd44a14bee6be82706a972dc7df 409 SUPERFAMILY SSF51735 108 295 2.46E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS11900 ec25edd44a14bee6be82706a972dc7df 409 Gene3D G3DSA:3.30.70.260 328 408 6.8E-16 T 28-03-2018 A6A12_RS11900 ec25edd44a14bee6be82706a972dc7df 409 Gene3D G3DSA:3.40.50.720 1 137 2.8E-42 T 28-03-2018 A6A12_RS11900 ec25edd44a14bee6be82706a972dc7df 409 Gene3D G3DSA:3.40.50.720 138 295 1.1E-43 T 28-03-2018 A6A12_RS11900 ec25edd44a14bee6be82706a972dc7df 409 SUPERFAMILY SSF52283 7 136 2.98E-48 T 28-03-2018 A6A12_RS11900 ec25edd44a14bee6be82706a972dc7df 409 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 229 245 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A6A12_RS11900 ec25edd44a14bee6be82706a972dc7df 409 SUPERFAMILY SSF55021 334 408 7.63E-18 T 28-03-2018 A6A12_RS03910 219e7b0a6830e8d798e94cc2d42f015d 144 Gene3D G3DSA:3.30.700.10 19 143 8.3E-20 T 28-03-2018 A6A12_RS03910 219e7b0a6830e8d798e94cc2d42f015d 144 Pfam PF07963 Prokaryotic N-terminal methylation motif 13 38 2.8E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS03910 219e7b0a6830e8d798e94cc2d42f015d 144 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 39 124 4.9E-16 T 28-03-2018 IPR031982 Type IV minor pilin ComP A6A12_RS03910 219e7b0a6830e8d798e94cc2d42f015d 144 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 17 38 1.6E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS03910 219e7b0a6830e8d798e94cc2d42f015d 144 SUPERFAMILY SSF54523 18 124 3.71E-18 T 28-03-2018 A6A12_RS04025 5ea36af71223af9eed13672856c48b46 170 Pfam PF13302 Acetyltransferase (GNAT) domain 10 141 6.6E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A6A12_RS04025 5ea36af71223af9eed13672856c48b46 170 SUPERFAMILY SSF55729 3 149 2.05E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS04025 5ea36af71223af9eed13672856c48b46 170 Gene3D G3DSA:3.40.630.30 4 170 9.1E-15 T 28-03-2018 A6A12_RS12375 3b1e92cac1bfcb91a1b48103e283c324 128 Pfam PF01196 Ribosomal protein L17 20 116 6.4E-35 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12375 3b1e92cac1bfcb91a1b48103e283c324 128 Gene3D G3DSA:3.90.1030.10 1 117 2.1E-50 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12375 3b1e92cac1bfcb91a1b48103e283c324 128 SUPERFAMILY SSF64263 1 119 3.01E-51 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12375 3b1e92cac1bfcb91a1b48103e283c324 128 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12375 3b1e92cac1bfcb91a1b48103e283c324 128 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 2.5E-49 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12375 3b1e92cac1bfcb91a1b48103e283c324 128 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.772 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS05980 a49e7c3f5a8b98f4fed12f5c61bd4285 321 SUPERFAMILY SSF53335 20 298 1.56E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS05980 a49e7c3f5a8b98f4fed12f5c61bd4285 321 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 36 321 9.4E-162 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 A6A12_RS05980 a49e7c3f5a8b98f4fed12f5c61bd4285 321 Gene3D G3DSA:3.40.50.150 146 315 4.5E-22 T 28-03-2018 A6A12_RS01715 0f51b600f4183ae50c9a405165a78e37 145 Pfam PF00582 Universal stress protein family 1 142 2.2E-33 T 28-03-2018 IPR006016 UspA GO:0006950 A6A12_RS01715 0f51b600f4183ae50c9a405165a78e37 145 PRINTS PR01438 Universal stress protein signature 120 142 5.3E-12 T 28-03-2018 IPR006015 Universal stress protein A A6A12_RS01715 0f51b600f4183ae50c9a405165a78e37 145 PRINTS PR01438 Universal stress protein signature 2 20 5.3E-12 T 28-03-2018 IPR006015 Universal stress protein A A6A12_RS01715 0f51b600f4183ae50c9a405165a78e37 145 PRINTS PR01438 Universal stress protein signature 102 114 5.3E-12 T 28-03-2018 IPR006015 Universal stress protein A A6A12_RS01715 0f51b600f4183ae50c9a405165a78e37 145 PIRSF PIRSF006276 1 145 2.9E-21 T 28-03-2018 IPR006015 Universal stress protein A A6A12_RS01715 0f51b600f4183ae50c9a405165a78e37 145 SUPERFAMILY SSF52402 2 143 6.45E-36 T 28-03-2018 A6A12_RS01715 0f51b600f4183ae50c9a405165a78e37 145 Gene3D G3DSA:3.40.50.620 1 145 1.2E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS05310 a6727c454ca03dc802e1e5b0c44b5c9e 415 PIRSF PIRSF003085 22 415 2.2E-121 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 A6A12_RS05310 a6727c454ca03dc802e1e5b0c44b5c9e 415 Pfam PF02353 Mycolic acid cyclopropane synthetase 139 407 1.7E-79 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS05310 a6727c454ca03dc802e1e5b0c44b5c9e 415 SUPERFAMILY SSF53335 20 367 6.09E-91 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS05310 a6727c454ca03dc802e1e5b0c44b5c9e 415 Gene3D G3DSA:3.40.50.150 134 413 8.5E-56 T 28-03-2018 A6A12_RS12760 bb10eeafc1d1a5ba203afdb0b1759ef0 877 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 1 877 17.833 T 28-03-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A6A12_RS12760 bb10eeafc1d1a5ba203afdb0b1759ef0 877 SUPERFAMILY SSF51621 6 877 0.0 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A6A12_RS12760 bb10eeafc1d1a5ba203afdb0b1759ef0 877 Pfam PF00311 Phosphoenolpyruvate carboxylase 129 877 1.7E-287 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A6A12_RS12760 bb10eeafc1d1a5ba203afdb0b1759ef0 877 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 535 547 - T 28-03-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A6A12_RS12760 bb10eeafc1d1a5ba203afdb0b1759ef0 877 Gene3D G3DSA:1.20.1440.90 274 386 8.6E-24 T 28-03-2018 A6A12_RS12760 bb10eeafc1d1a5ba203afdb0b1759ef0 877 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 134 145 - T 28-03-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A6A12_RS12760 bb10eeafc1d1a5ba203afdb0b1759ef0 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 245 260 1.8E-67 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A6A12_RS12760 bb10eeafc1d1a5ba203afdb0b1759ef0 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 707 733 1.8E-67 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A6A12_RS12760 bb10eeafc1d1a5ba203afdb0b1759ef0 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 533 553 1.8E-67 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A6A12_RS12760 bb10eeafc1d1a5ba203afdb0b1759ef0 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 575 604 1.8E-67 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A6A12_RS12760 bb10eeafc1d1a5ba203afdb0b1759ef0 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 186 202 1.8E-67 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A6A12_RS12760 bb10eeafc1d1a5ba203afdb0b1759ef0 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 133 146 1.8E-67 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A6A12_RS12760 bb10eeafc1d1a5ba203afdb0b1759ef0 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 384 404 1.8E-67 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 A6A12_RS02695 65fc2049f65881608ca0c3f396df561e 180 Pfam PF13505 Outer membrane protein beta-barrel domain 6 180 6.3E-14 T 28-03-2018 IPR027385 Outer membrane protein beta-barrel A6A12_RS02695 65fc2049f65881608ca0c3f396df561e 180 Gene3D G3DSA:2.40.160.20 17 180 4.7E-15 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A6A12_RS02695 65fc2049f65881608ca0c3f396df561e 180 SUPERFAMILY SSF56925 23 180 1.12E-17 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A6A12_RS00045 a2749fbe19372d146be8a3a05f97ccf1 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 245 260 9.7E-37 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00045 a2749fbe19372d146be8a3a05f97ccf1 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 49 61 9.7E-37 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00045 a2749fbe19372d146be8a3a05f97ccf1 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 398 417 9.7E-37 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00045 a2749fbe19372d146be8a3a05f97ccf1 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 9.7E-37 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00045 a2749fbe19372d146be8a3a05f97ccf1 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 322 338 9.7E-37 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00045 a2749fbe19372d146be8a3a05f97ccf1 693 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 554 1.1E-204 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00045 a2749fbe19372d146be8a3a05f97ccf1 693 SUPERFAMILY SSF109604 355 494 1.0E-12 T 28-03-2018 A6A12_RS00045 a2749fbe19372d146be8a3a05f97ccf1 693 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 3 692 9.6E-294 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00045 a2749fbe19372d146be8a3a05f97ccf1 693 Gene3D G3DSA:1.10.730.10 578 688 1.7E-13 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS00045 a2749fbe19372d146be8a3a05f97ccf1 693 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 691 25.944 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 A6A12_RS00045 a2749fbe19372d146be8a3a05f97ccf1 693 Pfam PF05746 DALR anticodon binding domain 585 682 3.4E-9 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A6A12_RS09075 e6769f282cb8c94ed78bbec21d83057f 129 Pfam PF07233 Protein of unknown function (DUF1425) 35 125 4.5E-28 T 28-03-2018 IPR010824 Protein of unknown function DUF1425 A6A12_RS04065 8d179a4303a5a13e47ceabeb1311a09d 254 Pfam PF01618 MotA/TolQ/ExbB proton channel family 99 212 2.8E-21 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 A6A12_RS04065 8d179a4303a5a13e47ceabeb1311a09d 254 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 182 199 - T 28-03-2018 IPR000540 Flagellar motor protein MotA, conserved site A6A12_RS04440 058ae16b695a8f697c21e04e86f9d81b 85 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site A6A12_RS04440 058ae16b695a8f697c21e04e86f9d81b 85 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site A6A12_RS04440 058ae16b695a8f697c21e04e86f9d81b 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 4.1E-27 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS04440 058ae16b695a8f697c21e04e86f9d81b 85 SUPERFAMILY SSF55594 1 82 9.16E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS04440 058ae16b695a8f697c21e04e86f9d81b 85 Gene3D G3DSA:3.30.1340.10 1 85 1.1E-30 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS04440 058ae16b695a8f697c21e04e86f9d81b 85 Pfam PF00381 PTS HPr component phosphorylation site 3 82 1.9E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS04440 058ae16b695a8f697c21e04e86f9d81b 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.3E-17 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS04440 058ae16b695a8f697c21e04e86f9d81b 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.3E-17 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS04440 058ae16b695a8f697c21e04e86f9d81b 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.3E-17 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like A6A12_RS07535 049ae12073f6c6fc483c51a5534bad05 176 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 14 105 2.5E-17 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 A6A12_RS07535 049ae12073f6c6fc483c51a5534bad05 176 SUPERFAMILY SSF50475 12 162 3.07E-33 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A6A12_RS07535 049ae12073f6c6fc483c51a5534bad05 176 Gene3D G3DSA:2.30.110.10 9 175 1.8E-26 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 A6A12_RS07535 049ae12073f6c6fc483c51a5534bad05 176 TIGRFAM TIGR04110 heme_HutZ: heme utilization protein HutZ 5 171 1.8E-86 T 28-03-2018 IPR014419 Heme utilization protein with pyridoxamine 5'-phosphate domain A6A12_RS07535 049ae12073f6c6fc483c51a5534bad05 176 PIRSF PIRSF004633 1 176 1.4E-75 T 28-03-2018 IPR014419 Heme utilization protein with pyridoxamine 5'-phosphate domain A6A12_RS14155 4c10d6d85fe19e57b1b11c0ef24fd8dc 320 SUPERFAMILY SSF52540 85 228 1.54E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS14155 4c10d6d85fe19e57b1b11c0ef24fd8dc 320 Pfam PF06414 Zeta toxin 79 272 1.2E-33 T 28-03-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 A6A12_RS14155 4c10d6d85fe19e57b1b11c0ef24fd8dc 320 Gene3D G3DSA:3.40.50.300 46 303 6.6E-8 T 28-03-2018 A6A12_RS01810 3d50839d3624adfafd133c0fb37aafb4 431 SUPERFAMILY SSF54534 281 383 7.2E-29 T 28-03-2018 A6A12_RS01810 3d50839d3624adfafd133c0fb37aafb4 431 Gene3D G3DSA:3.10.50.40 169 278 1.7E-23 T 28-03-2018 A6A12_RS01810 3d50839d3624adfafd133c0fb37aafb4 431 Pfam PF13616 PPIC-type PPIASE domain 166 272 6.4E-22 T 28-03-2018 A6A12_RS01810 3d50839d3624adfafd133c0fb37aafb4 431 Hamap MF_01183 Chaperone SurA [surA]. 11 426 31.66 T 28-03-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 A6A12_RS01810 3d50839d3624adfafd133c0fb37aafb4 431 Pfam PF00639 PPIC-type PPIASE domain 287 378 1.8E-21 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 A6A12_RS01810 3d50839d3624adfafd133c0fb37aafb4 431 Gene3D G3DSA:1.10.4030.10 25 150 4.7E-18 T 28-03-2018 A6A12_RS01810 3d50839d3624adfafd133c0fb37aafb4 431 SUPERFAMILY SSF109998 27 199 1.31E-34 T 28-03-2018 IPR027304 Trigger factor/SurA domain A6A12_RS01810 3d50839d3624adfafd133c0fb37aafb4 431 Pfam PF09312 SurA N-terminal domain 27 144 5.1E-41 T 28-03-2018 IPR015391 SurA N-terminal A6A12_RS01810 3d50839d3624adfafd133c0fb37aafb4 431 Gene3D G3DSA:3.10.50.40 279 384 4.5E-28 T 28-03-2018 A6A12_RS01810 3d50839d3624adfafd133c0fb37aafb4 431 SUPERFAMILY SSF54534 175 273 8.5E-25 T 28-03-2018 A6A12_RS06725 810142acd6c82383a2560ca5c5af9251 56 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 45 4.8E-21 T 28-03-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type A6A12_RS06725 810142acd6c82383a2560ca5c5af9251 56 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 48 1.7E-17 T 28-03-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type A6A12_RS02585 e41e1e766bf16fc56f431671e9260a51 246 Pfam PF07072 Cell division protein 18 224 2.5E-75 T 28-03-2018 IPR009777 Cell division protein ZapD A6A12_RS02585 e41e1e766bf16fc56f431671e9260a51 246 Hamap MF_01092 Cell division protein ZapD [zapD]. 3 245 32.7 T 28-03-2018 IPR009777 Cell division protein ZapD A6A12_RS02585 e41e1e766bf16fc56f431671e9260a51 246 SUPERFAMILY SSF160950 1 245 1.44E-91 T 28-03-2018 IPR009777 Cell division protein ZapD A6A12_RS02585 e41e1e766bf16fc56f431671e9260a51 246 Gene3D G3DSA:1.10.3900.10 12 173 4.5E-61 T 28-03-2018 A6A12_RS02585 e41e1e766bf16fc56f431671e9260a51 246 Gene3D G3DSA:2.60.440.10 174 245 2.0E-25 T 28-03-2018 IPR027462 Z ring-associated protein D, C-terminal domain A6A12_RS10450 47d2f2ab3fea43066ef0d26a90d4b1fb 358 Pfam PF01594 AI-2E family transporter 20 344 1.4E-75 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like A6A12_RS02390 7a4246d80b0439895814cc925ef7bc2a 161 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 35.908 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A6A12_RS02390 7a4246d80b0439895814cc925ef7bc2a 161 Gene3D G3DSA:3.30.1330.50 1 159 6.3E-72 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A6A12_RS02390 7a4246d80b0439895814cc925ef7bc2a 161 SUPERFAMILY SSF69765 1 158 2.09E-65 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A6A12_RS02390 7a4246d80b0439895814cc925ef7bc2a 161 Pfam PF02542 YgbB family 2 155 2.0E-65 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A6A12_RS02390 7a4246d80b0439895814cc925ef7bc2a 161 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 157 2.7E-69 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A6A12_RS02390 7a4246d80b0439895814cc925ef7bc2a 161 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 28-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 A6A12_RS05620 2b7f3b372b1b6ecf2fd9c8e60e2fc234 434 Gene3D G3DSA:3.40.1190.20 32 431 1.4E-43 T 28-03-2018 IPR029056 Ribokinase-like A6A12_RS05620 2b7f3b372b1b6ecf2fd9c8e60e2fc234 434 SUPERFAMILY SSF53613 338 417 3.74E-44 T 28-03-2018 IPR029056 Ribokinase-like A6A12_RS05620 2b7f3b372b1b6ecf2fd9c8e60e2fc234 434 SUPERFAMILY SSF53613 31 305 3.74E-44 T 28-03-2018 IPR029056 Ribokinase-like A6A12_RS05620 2b7f3b372b1b6ecf2fd9c8e60e2fc234 434 Pfam PF00294 pfkB family carbohydrate kinase 77 292 7.7E-12 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB A6A12_RS00920 637709c0709f3dcb41a724678d4b253f 181 Pfam PF00293 NUDIX domain 47 155 1.5E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A6A12_RS00920 637709c0709f3dcb41a724678d4b253f 181 Gene3D G3DSA:3.90.79.10 7 181 5.7E-35 T 28-03-2018 A6A12_RS00920 637709c0709f3dcb41a724678d4b253f 181 SUPERFAMILY SSF55811 8 178 1.62E-38 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 A6A12_RS00920 637709c0709f3dcb41a724678d4b253f 181 ProSitePatterns PS00893 Nudix box signature. 80 101 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A6A12_RS10060 21fab98ec69135bdf117ee0ecdb5949a 256 SUPERFAMILY SSF53474 5 254 5.32E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS10060 21fab98ec69135bdf117ee0ecdb5949a 256 Pfam PF12697 Alpha/beta hydrolase family 16 248 1.4E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A6A12_RS10060 21fab98ec69135bdf117ee0ecdb5949a 256 Gene3D G3DSA:3.40.50.1820 7 256 6.2E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS10060 21fab98ec69135bdf117ee0ecdb5949a 256 PRINTS PR00412 Epoxide hydrolase signature 82 95 4.6E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A6A12_RS10060 21fab98ec69135bdf117ee0ecdb5949a 256 PRINTS PR00412 Epoxide hydrolase signature 39 54 4.6E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A6A12_RS10060 21fab98ec69135bdf117ee0ecdb5949a 256 PRINTS PR00412 Epoxide hydrolase signature 231 253 4.6E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 A6A12_RS09740 dbbfe0f9f0c7ca858eb431092a00aa13 212 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 2 204 2.3E-66 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A6A12_RS09740 dbbfe0f9f0c7ca858eb431092a00aa13 212 Pfam PF01914 MarC family integral membrane protein 8 208 2.4E-64 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A6A12_RS07200 2beb67f25f50c0dc82ab0278ca2b5861 210 Pfam PF10816 Domain of unknown function (DUF2760) 87 209 6.7E-54 T 28-03-2018 IPR021212 Domain of unknown function DUF2760 A6A12_RS08865 f3e2fc27fc217d6cd411d3e3037d74c4 404 SUPERFAMILY SSF109604 181 399 9.42E-42 T 28-03-2018 A6A12_RS08865 f3e2fc27fc217d6cd411d3e3037d74c4 404 PIRSF PIRSF003180 1 403 1.0E-159 T 28-03-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing A6A12_RS08865 f3e2fc27fc217d6cd411d3e3037d74c4 404 SUPERFAMILY SSF141868 5 193 8.5E-28 T 28-03-2018 IPR001633 EAL domain A6A12_RS08865 f3e2fc27fc217d6cd411d3e3037d74c4 404 Pfam PF08668 HDOD domain 205 319 1.4E-13 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD A6A12_RS08865 f3e2fc27fc217d6cd411d3e3037d74c4 404 Gene3D G3DSA:1.10.3210.10 194 334 1.3E-16 T 28-03-2018 A6A12_RS08865 f3e2fc27fc217d6cd411d3e3037d74c4 404 Pfam PF00563 EAL domain 74 190 2.5E-14 T 28-03-2018 IPR001633 EAL domain A6A12_RS08865 f3e2fc27fc217d6cd411d3e3037d74c4 404 Gene3D G3DSA:3.20.20.450 4 193 2.3E-21 T 28-03-2018 IPR001633 EAL domain A6A12_RS08865 f3e2fc27fc217d6cd411d3e3037d74c4 404 SMART SM00052 2 195 1.8E-4 T 28-03-2018 IPR001633 EAL domain A6A12_RS07445 5826629d56ea0e04cc069a3716b6189a 396 SUPERFAMILY SSF53383 1 395 1.86E-109 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS07445 5826629d56ea0e04cc069a3716b6189a 396 Gene3D G3DSA:3.90.1150.10 241 396 5.7E-49 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS07445 5826629d56ea0e04cc069a3716b6189a 396 Gene3D G3DSA:3.90.1150.10 1 155 2.8E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS07445 5826629d56ea0e04cc069a3716b6189a 396 PRINTS PR00799 Aspartate aminotransferase signature 273 298 1.7E-38 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 A6A12_RS07445 5826629d56ea0e04cc069a3716b6189a 396 PRINTS PR00799 Aspartate aminotransferase signature 206 218 1.7E-38 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 A6A12_RS07445 5826629d56ea0e04cc069a3716b6189a 396 PRINTS PR00799 Aspartate aminotransferase signature 175 194 1.7E-38 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 A6A12_RS07445 5826629d56ea0e04cc069a3716b6189a 396 PRINTS PR00799 Aspartate aminotransferase signature 341 359 1.7E-38 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 A6A12_RS07445 5826629d56ea0e04cc069a3716b6189a 396 Pfam PF00155 Aminotransferase class I and II 26 391 8.4E-81 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A6A12_RS07445 5826629d56ea0e04cc069a3716b6189a 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 243 256 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A6A12_RS11580 52cc30fc80cd13cc79ea02d635181219 601 SUPERFAMILY SSF53822 454 597 1.81E-73 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A6A12_RS11580 52cc30fc80cd13cc79ea02d635181219 601 SUPERFAMILY SSF53822 260 426 1.81E-73 T 28-03-2018 IPR028082 Periplasmic binding protein-like I A6A12_RS11580 52cc30fc80cd13cc79ea02d635181219 601 Gene3D G3DSA:3.40.50.2300 257 415 2.4E-22 T 28-03-2018 A6A12_RS11580 52cc30fc80cd13cc79ea02d635181219 601 Gene3D G3DSA:3.40.50.2300 424 594 6.9E-9 T 28-03-2018 A6A12_RS11580 52cc30fc80cd13cc79ea02d635181219 601 Hamap MF_01890 Penicillin-binding protein activator LpoA [lpoA]. 1 601 29.104 T 28-03-2018 IPR007443 Penicillin-binding protein activator LpoA A6A12_RS11580 52cc30fc80cd13cc79ea02d635181219 601 Pfam PF04348 LppC putative lipoprotein 39 599 3.8E-184 T 28-03-2018 IPR007443 Penicillin-binding protein activator LpoA A6A12_RS01890 cec953e11405d6c517725494d9f40ece 306 Pfam PF04960 Glutaminase 22 306 9.0E-112 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A6A12_RS01890 cec953e11405d6c517725494d9f40ece 306 Gene3D G3DSA:3.40.710.10 1 306 2.6E-120 T 28-03-2018 A6A12_RS01890 cec953e11405d6c517725494d9f40ece 306 SUPERFAMILY SSF56601 5 306 1.88E-112 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A6A12_RS01890 cec953e11405d6c517725494d9f40ece 306 Hamap MF_00313 Glutaminase [glsA]. 4 306 46.408 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A6A12_RS01890 cec953e11405d6c517725494d9f40ece 306 TIGRFAM TIGR03814 Gln_ase: glutaminase A 8 306 4.0E-129 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 A6A12_RS08940 98d79dd1ba2e55fddecf6972a6b6f80b 758 SUPERFAMILY SSF51998 4 757 4.58E-289 T 28-03-2018 A6A12_RS08940 98d79dd1ba2e55fddecf6972a6b6f80b 758 Pfam PF01228 Glycine radical 628 739 2.3E-43 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 A6A12_RS08940 98d79dd1ba2e55fddecf6972a6b6f80b 758 Gene3D G3DSA:3.20.70.20 1 758 9.7E-294 T 28-03-2018 A6A12_RS08940 98d79dd1ba2e55fddecf6972a6b6f80b 758 PIRSF PIRSF000379 5 758 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 A6A12_RS08940 98d79dd1ba2e55fddecf6972a6b6f80b 758 Pfam PF02901 Pyruvate formate lyase-like 20 612 3.7E-205 T 28-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 A6A12_RS08940 98d79dd1ba2e55fddecf6972a6b6f80b 758 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 8 758 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 A6A12_RS08940 98d79dd1ba2e55fddecf6972a6b6f80b 758 ProSitePatterns PS00850 Glycine radical domain signature. 728 736 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site A6A12_RS01780 7335af271252315ffd1ed4c5e6f89fee 162 Pfam PF12821 Threonine/Serine exporter, ThrE 18 152 1.1E-34 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE A6A12_RS01875 d3a8e42a4233c7d2d980249c44bb20d7 90 PIRSF PIRSF029827 1 90 2.4E-44 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 A6A12_RS01875 d3a8e42a4233c7d2d980249c44bb20d7 90 SUPERFAMILY SSF111148 1 89 4.32E-41 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 A6A12_RS01875 d3a8e42a4233c7d2d980249c44bb20d7 90 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 28.614 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 A6A12_RS01875 d3a8e42a4233c7d2d980249c44bb20d7 90 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 76 6.0E-39 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 A6A12_RS01875 d3a8e42a4233c7d2d980249c44bb20d7 90 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 3.7E-43 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 A6A12_RS01875 d3a8e42a4233c7d2d980249c44bb20d7 90 Gene3D G3DSA:1.10.3880.10 2 89 2.4E-42 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 A6A12_RS07950 54fd7b13f9dfaed1954e97f02138b0dc 135 SUPERFAMILY SSF52540 15 133 1.42E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS07950 54fd7b13f9dfaed1954e97f02138b0dc 135 Pfam PF13671 AAA domain 16 114 7.8E-13 T 28-03-2018 A6A12_RS07950 54fd7b13f9dfaed1954e97f02138b0dc 135 Gene3D G3DSA:3.40.50.300 15 134 5.9E-13 T 28-03-2018 A6A12_RS06400 30ff6972a94abe84d16f6f65724ada46 236 SUPERFAMILY SSF48008 94 226 8.63E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A6A12_RS06400 30ff6972a94abe84d16f6f65724ada46 236 Gene3D G3DSA:1.20.120.530 83 236 2.3E-32 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal A6A12_RS06400 30ff6972a94abe84d16f6f65724ada46 236 Gene3D G3DSA:1.10.10.10 3 82 2.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS06400 30ff6972a94abe84d16f6f65724ada46 236 Pfam PF07729 FCD domain 97 222 5.3E-28 T 28-03-2018 IPR011711 GntR, C-terminal A6A12_RS06400 30ff6972a94abe84d16f6f65724ada46 236 SMART SM00895 97 224 5.0E-25 T 28-03-2018 IPR011711 GntR, C-terminal A6A12_RS06400 30ff6972a94abe84d16f6f65724ada46 236 SUPERFAMILY SSF46785 22 113 3.02E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS06400 30ff6972a94abe84d16f6f65724ada46 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 87 1.3E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A6A12_RS06400 30ff6972a94abe84d16f6f65724ada46 236 SMART SM00345 29 87 4.9E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A6A12_RS05055 00cf7a80a293ba53ed7e6c2aea653c54 322 Gene3D G3DSA:1.10.530.10 198 322 3.4E-35 T 28-03-2018 A6A12_RS05055 00cf7a80a293ba53ed7e6c2aea653c54 322 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 23 321 1.1E-109 T 28-03-2018 IPR011970 Lytic murein transglycosylase A6A12_RS05055 00cf7a80a293ba53ed7e6c2aea653c54 322 SUPERFAMILY SSF53955 8 321 2.01E-101 T 28-03-2018 IPR023346 Lysozyme-like domain A6A12_RS05055 00cf7a80a293ba53ed7e6c2aea653c54 322 Pfam PF13406 Transglycosylase SLT domain 23 318 1.1E-109 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 A6A12_RS05055 00cf7a80a293ba53ed7e6c2aea653c54 322 Gene3D G3DSA:1.10.8.350 87 192 4.4E-36 T 28-03-2018 A6A12_RS08640 ae23f9dfb32e683ab3fd336ac29f3fed 280 SUPERFAMILY SSF64182 1 271 4.19E-22 T 28-03-2018 A6A12_RS08640 ae23f9dfb32e683ab3fd336ac29f3fed 280 Pfam PF02272 DHHA1 domain 223 272 4.3E-10 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A6A12_RS08640 ae23f9dfb32e683ab3fd336ac29f3fed 280 Gene3D G3DSA:3.90.1640.10 9 114 5.9E-5 T 28-03-2018 A6A12_RS09605 6a918c8f8fbe0a64d6c78b4896edc84c 314 Gene3D G3DSA:2.40.50.180 39 103 1.3E-16 T 28-03-2018 A6A12_RS09605 6a918c8f8fbe0a64d6c78b4896edc84c 314 Pfam PF01584 CheW-like domain 21 160 1.0E-33 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS09605 6a918c8f8fbe0a64d6c78b4896edc84c 314 Gene3D G3DSA:3.40.50.2300 179 314 1.5E-21 T 28-03-2018 A6A12_RS09605 6a918c8f8fbe0a64d6c78b4896edc84c 314 PIRSF PIRSF002867 1 312 1.2E-103 T 28-03-2018 IPR024181 Chemotaxis response regulator CheV A6A12_RS09605 6a918c8f8fbe0a64d6c78b4896edc84c 314 SMART SM00448 184 305 1.7E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS09605 6a918c8f8fbe0a64d6c78b4896edc84c 314 SUPERFAMILY SSF52172 183 310 4.41E-22 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS09605 6a918c8f8fbe0a64d6c78b4896edc84c 314 SMART SM00260 17 158 1.0E-24 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS09605 6a918c8f8fbe0a64d6c78b4896edc84c 314 Pfam PF00072 Response regulator receiver domain 186 303 1.4E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS09605 6a918c8f8fbe0a64d6c78b4896edc84c 314 Gene3D G3DSA:2.30.30.40 104 158 4.2E-9 T 28-03-2018 A6A12_RS09605 6a918c8f8fbe0a64d6c78b4896edc84c 314 SUPERFAMILY SSF50341 16 161 6.41E-33 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS04680 32163481aec7a28f51da69a2076493e3 446 Pfam PF00756 Putative esterase 208 438 2.7E-35 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A6A12_RS04680 32163481aec7a28f51da69a2076493e3 446 SUPERFAMILY SSF53474 196 442 1.8E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS04680 32163481aec7a28f51da69a2076493e3 446 SUPERFAMILY SSF81296 30 180 6.3E-38 T 28-03-2018 IPR014756 Immunoglobulin E-set A6A12_RS04680 32163481aec7a28f51da69a2076493e3 446 Pfam PF11806 Domain of unknown function (DUF3327) 58 186 7.3E-35 T 28-03-2018 IPR021764 Enterochelin esterase, N-terminal GO:0005506|GO:0005737|GO:0006826|GO:0008849 A6A12_RS04680 32163481aec7a28f51da69a2076493e3 446 Gene3D G3DSA:2.60.40.10 31 173 9.1E-29 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS04680 32163481aec7a28f51da69a2076493e3 446 Gene3D G3DSA:3.40.50.1820 176 445 4.2E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS07380 9b8b8c37f25155618f820a851cb5705b 543 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 323 497 2.3E-37 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS07380 9b8b8c37f25155618f820a851cb5705b 543 SMART SM00283 271 532 2.6E-47 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS07380 9b8b8c37f25155618f820a851cb5705b 543 SMART SM00304 203 256 2.2E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 A6A12_RS07380 9b8b8c37f25155618f820a851cb5705b 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 369 396 9.8E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07380 9b8b8c37f25155618f820a851cb5705b 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 398 427 9.8E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07380 9b8b8c37f25155618f820a851cb5705b 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 4 29 9.8E-22 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 A6A12_RS07380 9b8b8c37f25155618f820a851cb5705b 543 SUPERFAMILY SSF58104 224 536 7.98E-61 T 28-03-2018 A6A12_RS07380 9b8b8c37f25155618f820a851cb5705b 543 Gene3D G3DSA:1.10.287.950 304 536 2.8E-45 T 28-03-2018 A6A12_RS07380 9b8b8c37f25155618f820a851cb5705b 543 Gene3D G3DSA:1.10.287.950 167 303 0.0035 T 28-03-2018 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 SUPERFAMILY SSF52935 323 469 1.44E-34 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 Gene3D G3DSA:3.40.1380.20 322 470 5.5E-45 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 469 5.9E-185 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 SUPERFAMILY SSF51621 1 74 3.45E-103 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 SUPERFAMILY SSF51621 156 339 3.45E-103 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 Pfam PF00224 Pyruvate kinase, barrel domain 1 340 6.4E-154 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 SUPERFAMILY SSF50800 70 167 4.71E-28 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 Gene3D G3DSA:3.20.20.60 160 321 9.1E-70 T 28-03-2018 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 Gene3D G3DSA:3.20.20.60 2 159 1.3E-35 T 28-03-2018 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 PRINTS PR01050 Pyruvate kinase family signature 186 200 1.2E-79 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 PRINTS PR01050 Pyruvate kinase family signature 244 268 1.2E-79 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.2E-79 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 PRINTS PR01050 Pyruvate kinase family signature 313 329 1.2E-79 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 PRINTS PR01050 Pyruvate kinase family signature 217 243 1.2E-79 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 PRINTS PR01050 Pyruvate kinase family signature 269 293 1.2E-79 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 PRINTS PR01050 Pyruvate kinase family signature 294 312 1.2E-79 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS02035 dea91f0e711d69cb27134086701ba1ae 470 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 468 7.7E-28 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A6A12_RS08415 d60c00ed208dc60222f1c19263ee1734 155 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 11 148 1.7E-23 T 28-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component A6A12_RS08415 d60c00ed208dc60222f1c19263ee1734 155 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 13 116 1.1E-11 T 28-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component A6A12_RS04255 e8ccd554511b569199f695b18a146046 497 SUPERFAMILY SSF52402 402 457 1.95E-5 T 28-03-2018 A6A12_RS04255 e8ccd554511b569199f695b18a146046 497 SUPERFAMILY SSF52402 190 342 1.95E-5 T 28-03-2018 A6A12_RS03225 e22af58db63764ad92d1368b0e8a2789 598 Gene3D G3DSA:3.40.50.720 395 552 0.0013 T 28-03-2018 A6A12_RS03225 e22af58db63764ad92d1368b0e8a2789 598 Pfam PF00999 Sodium/hydrogen exchanger family 12 386 5.9E-32 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A6A12_RS03225 e22af58db63764ad92d1368b0e8a2789 598 SUPERFAMILY SSF51735 399 494 3.26E-8 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS03225 e22af58db63764ad92d1368b0e8a2789 598 Pfam PF02254 TrkA-N domain 399 491 1.3E-5 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A6A12_RS02380 29c54ff9afd13c9a345e9bf4045e7051 98 Hamap MF_00599 Cell division protein FtsB [ftsB]. 6 95 34.487 T 28-03-2018 IPR023081 Cell division protein FtsB A6A12_RS02380 29c54ff9afd13c9a345e9bf4045e7051 98 Pfam PF04977 Septum formation initiator 16 94 2.9E-24 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 A6A12_RS11335 faeeadd436c28d151d1ee8e7aacef82b 474 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 441 2.0E-163 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS11335 faeeadd436c28d151d1ee8e7aacef82b 474 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 87 102 - T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS11335 faeeadd436c28d151d1ee8e7aacef82b 474 PRINTS PR00175 Sodium/alanine symporter signature 87 109 8.7E-57 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS11335 faeeadd436c28d151d1ee8e7aacef82b 474 PRINTS PR00175 Sodium/alanine symporter signature 410 430 8.7E-57 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS11335 faeeadd436c28d151d1ee8e7aacef82b 474 PRINTS PR00175 Sodium/alanine symporter signature 178 196 8.7E-57 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS11335 faeeadd436c28d151d1ee8e7aacef82b 474 PRINTS PR00175 Sodium/alanine symporter signature 206 225 8.7E-57 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS11335 faeeadd436c28d151d1ee8e7aacef82b 474 PRINTS PR00175 Sodium/alanine symporter signature 349 371 8.7E-57 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS11335 faeeadd436c28d151d1ee8e7aacef82b 474 PRINTS PR00175 Sodium/alanine symporter signature 303 321 8.7E-57 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS11335 faeeadd436c28d151d1ee8e7aacef82b 474 Pfam PF01235 Sodium:alanine symporter family 48 452 4.6E-162 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A6A12_RS07330 7a22517befd8861eca20ef014b193bd4 459 SUPERFAMILY SSF52540 246 354 5.87E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS07330 7a22517befd8861eca20ef014b193bd4 459 SUPERFAMILY SSF52540 87 137 5.87E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS07330 7a22517befd8861eca20ef014b193bd4 459 SUPERFAMILY SSF52540 21 40 5.87E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS07330 7a22517befd8861eca20ef014b193bd4 459 Gene3D G3DSA:3.40.50.300 15 416 1.1E-17 T 28-03-2018 A6A12_RS07330 7a22517befd8861eca20ef014b193bd4 459 PIRSF PIRSF019381 1 459 4.5E-198 T 28-03-2018 IPR007413 Protein of unknown function DUF463, YcjX-like protein A6A12_RS07330 7a22517befd8861eca20ef014b193bd4 459 Pfam PF04317 YcjX-like family, DUF463 20 458 2.4E-186 T 28-03-2018 IPR007413 Protein of unknown function DUF463, YcjX-like protein A6A12_RS09125 cf3b8c48b69f6ad3f405affa2fa8ad76 387 Gene3D G3DSA:3.90.1150.10 283 387 2.6E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS09125 cf3b8c48b69f6ad3f405affa2fa8ad76 387 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 26 381 4.2E-133 T 28-03-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 A6A12_RS09125 cf3b8c48b69f6ad3f405affa2fa8ad76 387 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 236 245 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 A6A12_RS09125 cf3b8c48b69f6ad3f405affa2fa8ad76 387 Pfam PF00155 Aminotransferase class I and II 46 378 1.4E-44 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A6A12_RS09125 cf3b8c48b69f6ad3f405affa2fa8ad76 387 SUPERFAMILY SSF53383 9 386 3.7E-90 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS09125 cf3b8c48b69f6ad3f405affa2fa8ad76 387 Gene3D G3DSA:3.40.640.10 59 282 6.0E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS04085 30efd4d664bab794dad5533df999d5f2 132 Pfam PF04241 Protein of unknown function (DUF423) 20 110 3.0E-30 T 28-03-2018 IPR006696 Protein of unknown function DUF423 A6A12_RS11410 dede3aab9339e44c7ae2e2221474c80e 1515 Pfam PF01493 GXGXG motif 1267 1451 3.3E-82 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A6A12_RS11410 dede3aab9339e44c7ae2e2221474c80e 1515 SUPERFAMILY SSF56235 21 447 2.74E-151 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A6A12_RS11410 dede3aab9339e44c7ae2e2221474c80e 1515 Gene3D G3DSA:3.20.20.70 801 1241 2.5E-158 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS11410 dede3aab9339e44c7ae2e2221474c80e 1515 SUPERFAMILY SSF51395 454 1221 6.51E-266 T 28-03-2018 A6A12_RS11410 dede3aab9339e44c7ae2e2221474c80e 1515 Pfam PF04898 Glutamate synthase central domain 472 756 2.7E-114 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 A6A12_RS11410 dede3aab9339e44c7ae2e2221474c80e 1515 Pfam PF01645 Conserved region in glutamate synthase 817 1187 1.0E-150 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 A6A12_RS11410 dede3aab9339e44c7ae2e2221474c80e 1515 Gene3D G3DSA:2.160.20.60 1242 1514 1.3E-107 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A6A12_RS11410 dede3aab9339e44c7ae2e2221474c80e 1515 SUPERFAMILY SSF69336 1235 1498 6.15E-94 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 A6A12_RS11410 dede3aab9339e44c7ae2e2221474c80e 1515 Pfam PF00310 Glutamine amidotransferases class-II 21 443 1.4E-184 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain A6A12_RS11410 dede3aab9339e44c7ae2e2221474c80e 1515 Gene3D G3DSA:3.20.20.70 453 800 2.2E-92 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS11410 dede3aab9339e44c7ae2e2221474c80e 1515 Gene3D G3DSA:3.60.20.10 21 452 7.6E-154 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A6A12_RS12685 0a9d731caa504cd8de39dfec1754eb9c 571 Pfam PF03958 Bacterial type II/III secretion system short domain 255 320 1.5E-10 T 28-03-2018 IPR005644 NolW-like A6A12_RS12685 0a9d731caa504cd8de39dfec1754eb9c 571 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 156 569 1.1E-160 T 28-03-2018 IPR013355 Type IV pilus secretin PilQ A6A12_RS12685 0a9d731caa504cd8de39dfec1754eb9c 571 SMART SM00965 181 229 2.3E-9 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 A6A12_RS12685 0a9d731caa504cd8de39dfec1754eb9c 571 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 515 548 - T 28-03-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 A6A12_RS12685 0a9d731caa504cd8de39dfec1754eb9c 571 Pfam PF00263 Bacterial type II and III secretion system protein 411 569 1.2E-45 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 A6A12_RS12685 0a9d731caa504cd8de39dfec1754eb9c 571 PRINTS PR00811 Bacterial general secretion pathway protein D signature 442 452 7.6E-20 T 28-03-2018 IPR001775 GspD/PilQ family A6A12_RS12685 0a9d731caa504cd8de39dfec1754eb9c 571 PRINTS PR00811 Bacterial general secretion pathway protein D signature 534 552 7.6E-20 T 28-03-2018 IPR001775 GspD/PilQ family A6A12_RS12685 0a9d731caa504cd8de39dfec1754eb9c 571 PRINTS PR00811 Bacterial general secretion pathway protein D signature 557 571 7.6E-20 T 28-03-2018 IPR001775 GspD/PilQ family A6A12_RS12685 0a9d731caa504cd8de39dfec1754eb9c 571 PRINTS PR00811 Bacterial general secretion pathway protein D signature 407 431 7.6E-20 T 28-03-2018 IPR001775 GspD/PilQ family A6A12_RS12685 0a9d731caa504cd8de39dfec1754eb9c 571 PRINTS PR00811 Bacterial general secretion pathway protein D signature 320 330 7.6E-20 T 28-03-2018 IPR001775 GspD/PilQ family A6A12_RS03930 9d56b6c10756b9622d1442150869d48e 137 Pfam PF07963 Prokaryotic N-terminal methylation motif 3 27 1.8E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS03930 9d56b6c10756b9622d1442150869d48e 137 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 27 3.3E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS03930 9d56b6c10756b9622d1442150869d48e 137 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site A6A12_RS05735 91c298d5bbf307a797c84b6714204baf 484 Gene3D G3DSA:3.40.50.2000 6 259 1.5E-5 T 28-03-2018 A6A12_RS05735 91c298d5bbf307a797c84b6714204baf 484 Gene3D G3DSA:3.40.50.2000 260 477 9.6E-39 T 28-03-2018 A6A12_RS05735 91c298d5bbf307a797c84b6714204baf 484 SUPERFAMILY SSF53756 7 483 4.89E-111 T 28-03-2018 A6A12_RS05735 91c298d5bbf307a797c84b6714204baf 484 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 6 479 3.5E-154 T 28-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 A6A12_RS05735 91c298d5bbf307a797c84b6714204baf 484 Pfam PF08323 Starch synthase catalytic domain 6 236 5.3E-66 T 28-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 A6A12_RS05735 91c298d5bbf307a797c84b6714204baf 484 Pfam PF00534 Glycosyl transferases group 1 298 442 1.9E-14 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 A6A12_RS05735 91c298d5bbf307a797c84b6714204baf 484 Hamap MF_00484 Glycogen synthase [glgA]. 4 481 40.22 T 28-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 A6A12_RS09680 999106e20a17a0ee7caf460bdd26bda1 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 76 2.0E-37 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A6A12_RS09680 999106e20a17a0ee7caf460bdd26bda1 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site A6A12_RS09680 999106e20a17a0ee7caf460bdd26bda1 77 Gene3D G3DSA:1.10.1200.10 1 77 6.0E-28 T 28-03-2018 A6A12_RS09680 999106e20a17a0ee7caf460bdd26bda1 77 Pfam PF00550 Phosphopantetheine attachment site 6 73 2.2E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A6A12_RS09680 999106e20a17a0ee7caf460bdd26bda1 77 SUPERFAMILY SSF47336 2 76 5.23E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A6A12_RS09680 999106e20a17a0ee7caf460bdd26bda1 77 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.891 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 A6A12_RS02835 f57b17430c627149835b2405d6a58c24 341 SUPERFAMILY SSF161098 96 287 1.57E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS02835 f57b17430c627149835b2405d6a58c24 341 Gene3D G3DSA:1.10.3720.10 3 296 7.5E-39 T 28-03-2018 A6A12_RS02835 f57b17430c627149835b2405d6a58c24 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 306 6.4E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS02835 f57b17430c627149835b2405d6a58c24 341 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 8 39 4.8E-6 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A6A12_RS05270 efa28f7e4c475bdcbd93c0470d878d2e 164 Gene3D G3DSA:1.10.10.10 7 63 2.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05270 efa28f7e4c475bdcbd93c0470d878d2e 164 SUPERFAMILY SSF46785 12 70 3.07E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05270 efa28f7e4c475bdcbd93c0470d878d2e 164 Pfam PF13412 Winged helix-turn-helix DNA-binding 12 59 2.2E-21 T 28-03-2018 A6A12_RS05270 efa28f7e4c475bdcbd93c0470d878d2e 164 Gene3D G3DSA:3.30.70.920 64 158 9.5E-27 T 28-03-2018 A6A12_RS05270 efa28f7e4c475bdcbd93c0470d878d2e 164 ProSitePatterns PS00519 AsnC-type HTH domain signature. 30 56 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A6A12_RS05270 efa28f7e4c475bdcbd93c0470d878d2e 164 SMART SM00344 12 121 2.3E-54 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A6A12_RS05270 efa28f7e4c475bdcbd93c0470d878d2e 164 Pfam PF01037 Lrp/AsnC ligand binding domain 78 152 2.7E-23 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A6A12_RS05270 efa28f7e4c475bdcbd93c0470d878d2e 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 6.2E-23 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A6A12_RS05270 efa28f7e4c475bdcbd93c0470d878d2e 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 6.2E-23 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A6A12_RS05270 efa28f7e4c475bdcbd93c0470d878d2e 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 6.2E-23 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 A6A12_RS05270 efa28f7e4c475bdcbd93c0470d878d2e 164 SUPERFAMILY SSF54909 74 157 1.88E-21 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel A6A12_RS09500 4b194f2108bc1c9d0f3e72f3054497c5 355 SUPERFAMILY SSF53686 22 335 4.71E-71 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A6A12_RS09500 4b194f2108bc1c9d0f3e72f3054497c5 355 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 36 316 2.8E-42 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A6A12_RS09500 4b194f2108bc1c9d0f3e72f3054497c5 355 Gene3D G3DSA:3.40.50.1100 34 140 4.9E-24 T 28-03-2018 A6A12_RS09500 4b194f2108bc1c9d0f3e72f3054497c5 355 Gene3D G3DSA:3.40.50.1100 141 331 1.8E-37 T 28-03-2018 A6A12_RS05795 81912e0ff4787ff38032d38561dbd721 1485 PIRSF PIRSF005246 1 1485 0.0 T 28-03-2018 IPR012090 Chromosome partition protein MukB GO:0003677|GO:0005524|GO:0007059|GO:0009295|GO:0030261 A6A12_RS05795 81912e0ff4787ff38032d38561dbd721 1485 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1337 1425 9.4E-15 T 28-03-2018 A6A12_RS05795 81912e0ff4787ff38032d38561dbd721 1485 Gene3D G3DSA:3.40.1140.10 1 227 5.9E-15 T 28-03-2018 A6A12_RS05795 81912e0ff4787ff38032d38561dbd721 1485 SUPERFAMILY SSF52540 26 224 2.8E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05795 81912e0ff4787ff38032d38561dbd721 1485 Pfam PF16330 MukB hinge domain 647 811 4.6E-72 T 28-03-2018 IPR032520 MukB, hinge domain A6A12_RS05795 81912e0ff4787ff38032d38561dbd721 1485 Pfam PF04310 MukB N-terminal 2 227 9.1E-122 T 28-03-2018 IPR007406 MukB, N-terminal domain GO:0003677|GO:0005524|GO:0007059|GO:0009295|GO:0030261 A6A12_RS05795 81912e0ff4787ff38032d38561dbd721 1485 Gene3D G3DSA:3.40.50.300 1139 1437 0.0033 T 28-03-2018 A6A12_RS05795 81912e0ff4787ff38032d38561dbd721 1485 Gene3D G3DSA:1.10.287.620 826 969 0.3 T 28-03-2018 A6A12_RS05795 81912e0ff4787ff38032d38561dbd721 1485 Gene3D G3DSA:1.10.287.620 976 1116 7.9E-4 T 28-03-2018 A6A12_RS02175 4affacd98f5660e79d5e6b15edf4c324 121 Pfam PF15933 Antitoxin to bacterial toxin RNase LS or RnlA 15 112 5.9E-31 T 28-03-2018 IPR031834 Antitoxin RnlB/LsoB A6A12_RS07805 fa9f77aeecf7dbf35ad65f71461e9661 593 PIRSF PIRSF028304 1 593 5.7E-124 T 28-03-2018 IPR010272 Type VI secretion system, TssF-like A6A12_RS07805 fa9f77aeecf7dbf35ad65f71461e9661 593 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 5 593 1.8E-136 T 28-03-2018 IPR010272 Type VI secretion system, TssF-like A6A12_RS07805 fa9f77aeecf7dbf35ad65f71461e9661 593 Pfam PF05947 Type VI secretion system, TssF 6 590 4.0E-136 T 28-03-2018 IPR010272 Type VI secretion system, TssF-like A6A12_RS11625 f9f22a5dac237531f2d9859d0e6ced9c 130 Gene3D G3DSA:3.30.230.10 3 130 2.8E-51 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A6A12_RS11625 f9f22a5dac237531f2d9859d0e6ced9c 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 33.602 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid A6A12_RS11625 f9f22a5dac237531f2d9859d0e6ced9c 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 A6A12_RS11625 f9f22a5dac237531f2d9859d0e6ced9c 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 9.4E-46 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 A6A12_RS11625 f9f22a5dac237531f2d9859d0e6ced9c 130 SUPERFAMILY SSF54211 5 130 5.31E-48 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A6A12_RS04385 b36ac171e1fd162b7022f8eb36e9d0f6 208 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 9 166 23.741 T 28-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 A6A12_RS04385 b36ac171e1fd162b7022f8eb36e9d0f6 208 Pfam PF04390 Lipopolysaccharide-assembly 39 161 1.2E-10 T 28-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 A6A12_RS04385 b36ac171e1fd162b7022f8eb36e9d0f6 208 Gene3D G3DSA:3.30.160.150 24 175 1.1E-41 T 28-03-2018 A6A12_RS07410 157bdfa8c86f3ec367d10e5de13c4068 184 Gene3D G3DSA:2.40.50.180 47 105 7.0E-20 T 28-03-2018 A6A12_RS07410 157bdfa8c86f3ec367d10e5de13c4068 184 SMART SM00260 24 165 4.0E-36 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS07410 157bdfa8c86f3ec367d10e5de13c4068 184 SUPERFAMILY SSF50341 27 169 8.76E-36 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS07410 157bdfa8c86f3ec367d10e5de13c4068 184 Pfam PF01584 CheW-like domain 28 166 1.2E-34 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 A6A12_RS07410 157bdfa8c86f3ec367d10e5de13c4068 184 Gene3D G3DSA:2.30.30.40 106 159 1.9E-15 T 28-03-2018 A6A12_RS08975 99eef5b9c522b14316badd67c199e8d4 423 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 423 40.504 T 28-03-2018 IPR006698 Uncharacterised protein family UPF0229 A6A12_RS08975 99eef5b9c522b14316badd67c199e8d4 423 Pfam PF04285 Protein of unknown function (DUF444) 3 421 2.3E-186 T 28-03-2018 IPR006698 Uncharacterised protein family UPF0229 A6A12_RS06225 c004d1850eac4c2fed1d1eb457481847 176 Pfam PF03802 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase 13 171 1.1E-45 T 28-03-2018 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 A6A12_RS06225 c004d1850eac4c2fed1d1eb457481847 176 TIGRFAM TIGR03124 citrate_citX: holo-ACP synthase CitX 13 170 3.3E-37 T 28-03-2018 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 A6A12_RS02600 a5b966638ad3a4aa618b2fdb64f0b824 408 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 168 196 - T 28-03-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 A6A12_RS02600 a5b966638ad3a4aa618b2fdb64f0b824 408 Pfam PF00482 Type II secretion system (T2SS), protein F 277 399 1.5E-27 T 28-03-2018 IPR018076 Type II secretion system F domain A6A12_RS02600 a5b966638ad3a4aa618b2fdb64f0b824 408 Pfam PF00482 Type II secretion system (T2SS), protein F 74 196 5.1E-32 T 28-03-2018 IPR018076 Type II secretion system F domain A6A12_RS02600 a5b966638ad3a4aa618b2fdb64f0b824 408 Gene3D G3DSA:3.30.70.1120 321 372 0.28 T 28-03-2018 A6A12_RS02600 a5b966638ad3a4aa618b2fdb64f0b824 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 168 196 4.1E-20 T 28-03-2018 IPR003004 GspF/PilC family A6A12_RS02600 a5b966638ad3a4aa618b2fdb64f0b824 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 372 386 4.1E-20 T 28-03-2018 IPR003004 GspF/PilC family A6A12_RS02600 a5b966638ad3a4aa618b2fdb64f0b824 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 388 407 4.1E-20 T 28-03-2018 IPR003004 GspF/PilC family A6A12_RS02600 a5b966638ad3a4aa618b2fdb64f0b824 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 69 81 4.1E-20 T 28-03-2018 IPR003004 GspF/PilC family A6A12_RS08820 3cd22e08fd674eb53e4dbf06352a574e 35 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 30 1.1E-20 T 28-03-2018 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 A6A12_RS08820 3cd22e08fd674eb53e4dbf06352a574e 35 Pfam PF08173 Membrane bound YbgT-like protein 1 27 1.3E-17 T 28-03-2018 IPR012994 Membrane bound YbgT-like A6A12_RS14245 832b95cb5dd779b81c6571b622ae2dbd 262 SUPERFAMILY SSF69572 3 249 6.02E-78 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A6A12_RS14245 832b95cb5dd779b81c6571b622ae2dbd 262 Gene3D G3DSA:3.40.50.720 1 248 1.3E-67 T 28-03-2018 A6A12_RS14245 832b95cb5dd779b81c6571b622ae2dbd 262 Pfam PF00899 ThiF family 10 243 2.1E-61 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A6A12_RS10665 9b1b57e89d64dd38779c7b2ba4f2cf1c 248 Gene3D G3DSA:3.90.1210.10 127 187 5.1E-4 T 28-03-2018 A6A12_RS10665 9b1b57e89d64dd38779c7b2ba4f2cf1c 248 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 114 247 3.3E-36 T 28-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal A6A12_RS10665 9b1b57e89d64dd38779c7b2ba4f2cf1c 248 SMART SM00858 126 188 3.1E-6 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 A6A12_RS10665 9b1b57e89d64dd38779c7b2ba4f2cf1c 248 Pfam PF13144 Chaperone for flagella basal body P-ring formation 49 246 1.1E-49 T 28-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal A6A12_RS13205 831ec50ad48a0d1405148adaa1332aff 476 SUPERFAMILY SSF52540 245 474 4.39E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13205 831ec50ad48a0d1405148adaa1332aff 476 Gene3D G3DSA:3.40.50.300 246 476 6.3E-11 T 28-03-2018 A6A12_RS00935 317f030af144f2993062aaf07abcdee1 254 SUPERFAMILY SSF53474 5 252 4.32E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS00935 317f030af144f2993062aaf07abcdee1 254 Gene3D G3DSA:3.40.50.1820 2 254 2.4E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold A6A12_RS00935 317f030af144f2993062aaf07abcdee1 254 Pfam PF00561 alpha/beta hydrolase fold 16 241 4.2E-26 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 A6A12_RS00935 317f030af144f2993062aaf07abcdee1 254 Hamap MF_01260 Pimeloyl-[acyl-carrier protein] methyl ester esterase [bioH]. 5 254 44.919 T 28-03-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 A6A12_RS00935 317f030af144f2993062aaf07abcdee1 254 TIGRFAM TIGR01738 bioH: pimelyl-[acyl-carrier protein] methyl ester esterase 12 252 2.4E-105 T 28-03-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 A6A12_RS00025 0de9344e186cf63bb5699d019dae1122 90 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 8 80 1.4E-7 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A6A12_RS00025 0de9344e186cf63bb5699d019dae1122 90 Gene3D G3DSA:3.10.50.30 2 81 3.0E-9 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 A6A12_RS00025 0de9344e186cf63bb5699d019dae1122 90 SUPERFAMILY SSF54534 7 81 7.46E-8 T 28-03-2018 A6A12_RS14440 70f6b17e907102331ffabd196d282cb4 249 SMART SM00382 26 223 2.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS14440 70f6b17e907102331ffabd196d282cb4 249 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS14440 70f6b17e907102331ffabd196d282cb4 249 Pfam PF00005 ABC transporter 17 168 9.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS14440 70f6b17e907102331ffabd196d282cb4 249 Gene3D G3DSA:3.40.50.300 1 248 1.3E-75 T 28-03-2018 A6A12_RS14440 70f6b17e907102331ffabd196d282cb4 249 SUPERFAMILY SSF52540 1 238 4.26E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS14440 70f6b17e907102331ffabd196d282cb4 249 PIRSF PIRSF039085 1 244 4.1E-105 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 A6A12_RS01945 72c2e7d8a4f57f5287ca163dc5aa0385 187 SUPERFAMILY SSF143456 1 187 9.16E-68 T 28-03-2018 A6A12_RS01945 72c2e7d8a4f57f5287ca163dc5aa0385 187 Gene3D G3DSA:3.40.1740.10 111 179 4.9E-13 T 28-03-2018 A6A12_RS01945 72c2e7d8a4f57f5287ca163dc5aa0385 187 Gene3D G3DSA:3.40.1740.10 1 95 1.8E-28 T 28-03-2018 A6A12_RS01945 72c2e7d8a4f57f5287ca163dc5aa0385 187 Pfam PF02622 Uncharacterized ACR, COG1678 12 174 3.5E-50 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 A6A12_RS01945 72c2e7d8a4f57f5287ca163dc5aa0385 187 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 1 187 39.31 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 A6A12_RS09600 8c4c53e7da627f9934e15f224a609f4f 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A6A12_RS09600 8c4c53e7da627f9934e15f224a609f4f 247 Pfam PF00106 short chain dehydrogenase 14 208 1.7E-49 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09600 8c4c53e7da627f9934e15f224a609f4f 247 SUPERFAMILY SSF51735 10 242 1.28E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS09600 8c4c53e7da627f9934e15f224a609f4f 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 2.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09600 8c4c53e7da627f9934e15f224a609f4f 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 2.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09600 8c4c53e7da627f9934e15f224a609f4f 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 2.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09600 8c4c53e7da627f9934e15f224a609f4f 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 2.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09600 8c4c53e7da627f9934e15f224a609f4f 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 2.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09600 8c4c53e7da627f9934e15f224a609f4f 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09600 8c4c53e7da627f9934e15f224a609f4f 247 Gene3D G3DSA:3.40.50.720 7 247 4.1E-58 T 28-03-2018 A6A12_RS10300 39934935ab0bb4cecbd1a0edd0107dcd 95 PIRSF PIRSF037266 1 94 8.0E-41 T 28-03-2018 IPR017162 Uncharacterised conserved protein UCP037266 A6A12_RS10300 39934935ab0bb4cecbd1a0edd0107dcd 95 Pfam PF09904 Winged helix-turn helix 4 90 1.9E-37 T 28-03-2018 IPR017162 Uncharacterised conserved protein UCP037266 A6A12_RS04345 4bd663523840febcd0b1467beb1c0496 92 SUPERFAMILY SSF117991 7 92 6.15E-30 T 28-03-2018 IPR027471 YbeD-like domain A6A12_RS04345 4bd663523840febcd0b1467beb1c0496 92 Gene3D G3DSA:3.30.70.260 10 92 1.9E-29 T 28-03-2018 A6A12_RS04345 4bd663523840febcd0b1467beb1c0496 92 Pfam PF04359 Protein of unknown function (DUF493) 12 92 3.0E-28 T 28-03-2018 IPR007454 Uncharacterised protein family UPF0250 A6A12_RS04345 4bd663523840febcd0b1467beb1c0496 92 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 6 92 25.583 T 28-03-2018 IPR007454 Uncharacterised protein family UPF0250 A6A12_RS04725 3840e14645c8c59a6507d1020f9fe04f 258 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 234 253 1.0E-52 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A6A12_RS04725 3840e14645c8c59a6507d1020f9fe04f 258 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 12 29 1.0E-52 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A6A12_RS04725 3840e14645c8c59a6507d1020f9fe04f 258 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 208 227 1.0E-52 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A6A12_RS04725 3840e14645c8c59a6507d1020f9fe04f 258 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 104 124 1.0E-52 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A6A12_RS04725 3840e14645c8c59a6507d1020f9fe04f 258 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 84 101 1.0E-52 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A6A12_RS04725 3840e14645c8c59a6507d1020f9fe04f 258 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 169 192 1.0E-52 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A6A12_RS04725 3840e14645c8c59a6507d1020f9fe04f 258 SUPERFAMILY SSF51735 6 256 6.54E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS04725 3840e14645c8c59a6507d1020f9fe04f 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A6A12_RS04725 3840e14645c8c59a6507d1020f9fe04f 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 255 8.1E-48 T 28-03-2018 A6A12_RS04725 3840e14645c8c59a6507d1020f9fe04f 258 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 8 257 3.4E-111 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 A6A12_RS04725 3840e14645c8c59a6507d1020f9fe04f 258 Gene3D G3DSA:3.40.50.720 5 258 5.8E-59 T 28-03-2018 A6A12_RS12860 3186725c3875d05dde7d217493382143 115 SUPERFAMILY SSF55331 2 115 2.5E-34 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily A6A12_RS12860 3186725c3875d05dde7d217493382143 115 Pfam PF02962 5-carboxymethyl-2-hydroxymuconate isomerase 2 91 3.5E-6 T 28-03-2018 IPR004220 5-carboxymethyl-2-hydroxymuconate isomerase GO:0008704|GO:0019439 KEGG: 00350+5.3.3.10 A6A12_RS12860 3186725c3875d05dde7d217493382143 115 Gene3D G3DSA:3.30.429.10 1 115 5.6E-32 T 28-03-2018 A6A12_RS09150 c17c1b587cf155a3c689885d7a7ab131 200 Gene3D G3DSA:2.50.20.10 18 199 6.6E-37 T 28-03-2018 A6A12_RS09150 c17c1b587cf155a3c689885d7a7ab131 200 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 7 199 7.7E-64 T 28-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 A6A12_RS09150 c17c1b587cf155a3c689885d7a7ab131 200 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 33 188 7.5E-53 T 28-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like A6A12_RS09150 c17c1b587cf155a3c689885d7a7ab131 200 SUPERFAMILY SSF89392 22 199 4.32E-52 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX A6A12_RS09150 c17c1b587cf155a3c689885d7a7ab131 200 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 5 198 31.795 T 28-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 A6A12_RS12265 decc6dc03387c5618851d1bef540f34f 97 Pfam PF10795 Protein of unknown function (DUF2607) 3 96 7.0E-41 T 28-03-2018 IPR019731 Protein of unknown function DUF2607 A6A12_RS08015 7d68fd638cd8babb930ceb148ba38d2b 342 SUPERFAMILY SSF53187 9 329 1.03E-76 T 28-03-2018 A6A12_RS08015 7d68fd638cd8babb930ceb148ba38d2b 342 Gene3D G3DSA:3.40.630.10 47 310 2.0E-23 T 28-03-2018 A6A12_RS08015 7d68fd638cd8babb930ceb148ba38d2b 342 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 54 330 8.7E-71 T 28-03-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 A6A12_RS08015 7d68fd638cd8babb930ceb148ba38d2b 342 Hamap MF_00767 Succinylglutamate desuccinylase [astE]. 1 342 129.435 T 28-03-2018 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96 A6A12_RS08015 7d68fd638cd8babb930ceb148ba38d2b 342 PIRSF PIRSF017020 4 336 6.1E-121 T 28-03-2018 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96 A6A12_RS00665 29eddc0cffc8ff7dd82ef50e6241e4fa 145 Pfam PF10008 Uncharacterized protein conserved in bacteria (DUF2251) 35 124 1.2E-31 T 28-03-2018 IPR014449 Uncharacterised conserved protein UCP007050, HI0931 A6A12_RS02960 b8e8811461102505b639556e286d8329 151 SUPERFAMILY SSF75420 2 83 4.97E-26 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal A6A12_RS02960 b8e8811461102505b639556e286d8329 151 Gene3D G3DSA:3.30.300.70 1 80 3.5E-28 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal A6A12_RS02960 b8e8811461102505b639556e286d8329 151 Gene3D G3DSA:2.30.30.180 88 148 2.8E-16 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal A6A12_RS02960 b8e8811461102505b639556e286d8329 151 Pfam PF02576 RimP N-terminal domain 13 83 1.3E-29 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal A6A12_RS02960 b8e8811461102505b639556e286d8329 151 SUPERFAMILY SSF74942 84 151 4.84E-17 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal A6A12_RS02960 b8e8811461102505b639556e286d8329 151 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 151 24.589 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 A6A12_RS02960 b8e8811461102505b639556e286d8329 151 Pfam PF17384 RimP C-terminal SH3 domain 86 151 9.9E-20 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal A6A12_RS07890 e6ee2ada7f6306d642a3ba67a09a7e1c 353 Gene3D G3DSA:3.30.70.270 163 337 2.3E-48 T 28-03-2018 A6A12_RS07890 e6ee2ada7f6306d642a3ba67a09a7e1c 353 SUPERFAMILY SSF55073 184 335 1.8E-40 T 28-03-2018 IPR029787 Nucleotide cyclase A6A12_RS07890 e6ee2ada7f6306d642a3ba67a09a7e1c 353 SMART SM00267 168 336 2.8E-49 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS07890 e6ee2ada7f6306d642a3ba67a09a7e1c 353 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 177 334 4.2E-38 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS07890 e6ee2ada7f6306d642a3ba67a09a7e1c 353 Pfam PF00990 Diguanylate cyclase, GGDEF domain 179 332 1.0E-34 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS07915 9400101a078e19299c2ffecf12f06832 226 Pfam PF00072 Response regulator receiver domain 5 116 1.3E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS07915 9400101a078e19299c2ffecf12f06832 226 Pfam PF12431 Transcriptional regulator 132 160 1.7E-7 T 28-03-2018 IPR028141 Transcriptional regulator A6A12_RS07915 9400101a078e19299c2ffecf12f06832 226 SMART SM00448 3 116 1.6E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS07915 9400101a078e19299c2ffecf12f06832 226 Gene3D G3DSA:3.40.50.2300 2 140 3.4E-28 T 28-03-2018 A6A12_RS07915 9400101a078e19299c2ffecf12f06832 226 SUPERFAMILY SSF52172 3 123 1.29E-31 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS07915 9400101a078e19299c2ffecf12f06832 226 Gene3D G3DSA:1.10.10.10 141 223 1.8E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS07915 9400101a078e19299c2ffecf12f06832 226 PIRSF PIRSF006171 1 226 3.8E-80 T 28-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 A6A12_RS12110 d9732978fc4abad353bf8a4b83434058 212 Pfam PF05494 MlaC protein 33 199 2.5E-48 T 28-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC A6A12_RS12110 d9732978fc4abad353bf8a4b83434058 212 PIRSF PIRSF004649 1 211 5.2E-56 T 28-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC A6A12_RS12110 d9732978fc4abad353bf8a4b83434058 212 Gene3D G3DSA:3.10.450.50 27 87 4.2E-6 T 28-03-2018 A6A12_RS12110 d9732978fc4abad353bf8a4b83434058 212 Gene3D G3DSA:3.10.450.50 88 172 1.0E-19 T 28-03-2018 A6A12_RS01910 2dadfec9d3492b4675cfc433b2d7f0f5 96 Gene3D G3DSA:3.30.1200.10 2 96 1.4E-29 T 28-03-2018 IPR003746 Protein of unknown function DUF167 A6A12_RS01910 2dadfec9d3492b4675cfc433b2d7f0f5 96 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 12 82 6.1E-26 T 28-03-2018 IPR003746 Protein of unknown function DUF167 A6A12_RS01910 2dadfec9d3492b4675cfc433b2d7f0f5 96 SMART SM01152 8 84 1.0E-38 T 28-03-2018 IPR003746 Protein of unknown function DUF167 A6A12_RS01910 2dadfec9d3492b4675cfc433b2d7f0f5 96 Hamap MF_00634 UPF0235 protein YggU [yggU]. 8 94 20.187 T 28-03-2018 IPR003746 Protein of unknown function DUF167 A6A12_RS01910 2dadfec9d3492b4675cfc433b2d7f0f5 96 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 8 89 7.2E-27 T 28-03-2018 IPR005228 Conserved hypothetical protein CHP00251 A6A12_RS01910 2dadfec9d3492b4675cfc433b2d7f0f5 96 SUPERFAMILY SSF69786 3 95 1.12E-31 T 28-03-2018 IPR003746 Protein of unknown function DUF167 A6A12_RS09835 910ec6651b80c24e3812356f9ab8cd47 165 Pfam PF03918 Cytochrome C biogenesis protein 10 151 1.7E-53 T 28-03-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family A6A12_RS00100 a0be918f5327b4f8af8cea161adc1e94 94 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 3 70 0.003 T 28-03-2018 A6A12_RS00100 a0be918f5327b4f8af8cea161adc1e94 94 Gene3D G3DSA:3.30.70.260 1 90 8.1E-9 T 28-03-2018 A6A12_RS00100 a0be918f5327b4f8af8cea161adc1e94 94 SUPERFAMILY SSF55021 3 74 3.46E-10 T 28-03-2018 A6A12_RS00100 a0be918f5327b4f8af8cea161adc1e94 94 Pfam PF13710 ACT domain 12 73 5.5E-21 T 28-03-2018 A6A12_RS13295 b8223d764fd689b500e07d63f9cca30e 294 TIGRFAM TIGR01556 rhamnosyltran: rhamnosyltransferase 8 289 4.8E-65 T 28-03-2018 IPR006446 Rhamnosyltransferase A6A12_RS13295 b8223d764fd689b500e07d63f9cca30e 294 Pfam PF00535 Glycosyl transferase family 2 6 174 1.9E-25 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A6A12_RS13295 b8223d764fd689b500e07d63f9cca30e 294 Gene3D G3DSA:3.90.550.10 2 242 3.9E-20 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13295 b8223d764fd689b500e07d63f9cca30e 294 SUPERFAMILY SSF53448 6 271 3.84E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS00580 dd8e007ff3803ca93814c9de58d11fcf 284 Pfam PF01040 UbiA prenyltransferase family 24 266 1.1E-65 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A6A12_RS00580 dd8e007ff3803ca93814c9de58d11fcf 284 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 8 283 5.4E-105 T 28-03-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 A6A12_RS00580 dd8e007ff3803ca93814c9de58d11fcf 284 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 1 284 29.273 T 28-03-2018 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 A6A12_RS10720 3a6163ed77ad8ae731248d794d9b8126 149 Pfam PF04214 Protein of unknown function, DUF 51 120 1.3E-32 T 28-03-2018 IPR007332 Protein of unknown function DUF411 A6A12_RS10720 3a6163ed77ad8ae731248d794d9b8126 149 SUPERFAMILY SSF52833 26 100 8.95E-5 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS10880 431633f83524191b6b178cfdc6815033 402 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 132 1.1E-46 T 28-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A6A12_RS10880 431633f83524191b6b178cfdc6815033 402 SUPERFAMILY SSF51735 2 150 1.98E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS10880 431633f83524191b6b178cfdc6815033 402 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 396 45.985 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A6A12_RS10880 431633f83524191b6b178cfdc6815033 402 SUPERFAMILY SSF55347 126 274 6.54E-62 T 28-03-2018 A6A12_RS10880 431633f83524191b6b178cfdc6815033 402 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 395 2.3E-161 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A6A12_RS10880 431633f83524191b6b178cfdc6815033 402 SUPERFAMILY SSF69055 301 399 4.19E-30 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A6A12_RS10880 431633f83524191b6b178cfdc6815033 402 Pfam PF13288 DXP reductoisomerase C-terminal domain 271 391 2.7E-38 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A6A12_RS10880 431633f83524191b6b178cfdc6815033 402 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 146 239 1.7E-36 T 28-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A6A12_RS10880 431633f83524191b6b178cfdc6815033 402 Gene3D G3DSA:1.10.1740.10 312 400 1.8E-28 T 28-03-2018 A6A12_RS10880 431633f83524191b6b178cfdc6815033 402 Gene3D G3DSA:3.40.50.720 1 150 3.6E-49 T 28-03-2018 A6A12_RS10880 431633f83524191b6b178cfdc6815033 402 PIRSF PIRSF006205 1 402 1.6E-153 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 A6A12_RS06010 082c247de5e840647d836327daf259aa 147 Pfam PF03724 META domain 33 139 3.3E-29 T 28-03-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ A6A12_RS01025 21d119152e3688a8ba016f7c0716961b 207 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 4 184 6.1E-75 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 A6A12_RS01025 21d119152e3688a8ba016f7c0716961b 207 Hamap MF_00328 Guanylate kinase [gmk]. 2 187 37.285 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 A6A12_RS01025 21d119152e3688a8ba016f7c0716961b 207 SUPERFAMILY SSF52540 3 189 1.75E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS01025 21d119152e3688a8ba016f7c0716961b 207 Pfam PF00625 Guanylate kinase 5 185 3.2E-60 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit A6A12_RS01025 21d119152e3688a8ba016f7c0716961b 207 Gene3D G3DSA:3.40.50.300 1 204 2.0E-63 T 28-03-2018 A6A12_RS01025 21d119152e3688a8ba016f7c0716961b 207 SMART SM00072 3 187 3.8E-72 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit A6A12_RS01025 21d119152e3688a8ba016f7c0716961b 207 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 A6A12_RS07560 6196117ae0c14d78bbaa8d6bc3149a5c 282 Pfam PF01497 Periplasmic binding protein 28 257 2.1E-38 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 A6A12_RS07560 6196117ae0c14d78bbaa8d6bc3149a5c 282 Gene3D G3DSA:3.40.50.1980 25 138 1.2E-19 T 28-03-2018 A6A12_RS07560 6196117ae0c14d78bbaa8d6bc3149a5c 282 SUPERFAMILY SSF53807 26 282 5.49E-49 T 28-03-2018 A6A12_RS07560 6196117ae0c14d78bbaa8d6bc3149a5c 282 Gene3D G3DSA:3.40.50.1980 139 282 9.7E-25 T 28-03-2018 A6A12_RS10115 fbd9ec695456252edbdc0eb68125b552 675 Pfam PF01266 FAD dependent oxidoreductase 265 636 2.0E-42 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A6A12_RS10115 fbd9ec695456252edbdc0eb68125b552 675 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 5 661 27.171 T 28-03-2018 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 A6A12_RS10115 fbd9ec695456252edbdc0eb68125b552 675 SUPERFAMILY SSF51905 264 481 3.04E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS10115 fbd9ec695456252edbdc0eb68125b552 675 SUPERFAMILY SSF51905 574 662 3.04E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS10115 fbd9ec695456252edbdc0eb68125b552 675 Gene3D G3DSA:3.50.50.60 253 675 1.7E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS10115 fbd9ec695456252edbdc0eb68125b552 675 Gene3D G3DSA:3.40.50.150 7 252 2.7E-80 T 28-03-2018 A6A12_RS10115 fbd9ec695456252edbdc0eb68125b552 675 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 265 666 1.0E-151 T 28-03-2018 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 A6A12_RS10115 fbd9ec695456252edbdc0eb68125b552 675 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 116 242 6.4E-47 T 28-03-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 A6A12_RS06875 16a1a826fd1f8a510d3b512d8dfe42d5 113 Pfam PF12290 Protein of unknown function (DUF3802) 2 109 2.0E-41 T 28-03-2018 IPR020979 Uncharacterised protein family A0KLC6 A6A12_RS08195 d923ed3a72f4a29f5b7c41f9f8681187 255 SUPERFAMILY SSF81301 13 80 4.73E-8 T 28-03-2018 A6A12_RS08195 d923ed3a72f4a29f5b7c41f9f8681187 255 Gene3D G3DSA:3.30.460.10 6 134 1.3E-12 T 28-03-2018 A6A12_RS05435 38b44d909fa918caf01946d698680b45 289 Gene3D G3DSA:3.20.20.140 1 261 1.3E-44 T 28-03-2018 A6A12_RS05435 38b44d909fa918caf01946d698680b45 289 SMART SM00481 3 70 1.3E-13 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A6A12_RS05435 38b44d909fa918caf01946d698680b45 289 Pfam PF02811 PHP domain 4 173 2.3E-7 T 28-03-2018 IPR004013 PHP domain GO:0003824 A6A12_RS05435 38b44d909fa918caf01946d698680b45 289 SUPERFAMILY SSF89550 165 275 1.2E-52 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A6A12_RS05435 38b44d909fa918caf01946d698680b45 289 SUPERFAMILY SSF89550 1 83 1.2E-52 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A6A12_RS06205 9aacbab6738797ba14732c1edba007ef 330 PIRSF PIRSF017082 1 330 7.7E-99 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 A6A12_RS06205 9aacbab6738797ba14732c1edba007ef 330 SUPERFAMILY SSF53850 31 234 9.77E-7 T 28-03-2018 A6A12_RS06205 9aacbab6738797ba14732c1edba007ef 330 Gene3D G3DSA:3.40.190.10 125 234 5.0E-11 T 28-03-2018 A6A12_RS06205 9aacbab6738797ba14732c1edba007ef 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 66 325 2.7E-25 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 A6A12_RS03215 16622dde26ff9098d0f5696518206f86 494 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 328 436 4.0E-21 T 28-03-2018 IPR025299 CstA, C-terminal domain A6A12_RS03215 16622dde26ff9098d0f5696518206f86 494 Pfam PF02554 Carbon starvation protein CstA 4 144 3.8E-34 T 28-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 A6A12_RS03215 16622dde26ff9098d0f5696518206f86 494 Pfam PF02554 Carbon starvation protein CstA 149 293 1.1E-19 T 28-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 A6A12_RS11870 1c77e4cc3abf8bbc186a8a288baa9935 395 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 298 311 - T 28-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 A6A12_RS11870 1c77e4cc3abf8bbc186a8a288baa9935 395 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 7 390 2.9E-123 T 28-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 A6A12_RS11870 1c77e4cc3abf8bbc186a8a288baa9935 395 Gene3D G3DSA:3.50.50.60 4 355 2.3E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS11870 1c77e4cc3abf8bbc186a8a288baa9935 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 4.8E-11 T 28-03-2018 A6A12_RS11870 1c77e4cc3abf8bbc186a8a288baa9935 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 4.8E-11 T 28-03-2018 A6A12_RS11870 1c77e4cc3abf8bbc186a8a288baa9935 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 160 175 4.8E-11 T 28-03-2018 A6A12_RS11870 1c77e4cc3abf8bbc186a8a288baa9935 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 4.8E-11 T 28-03-2018 A6A12_RS11870 1c77e4cc3abf8bbc186a8a288baa9935 395 SUPERFAMILY SSF51905 5 181 1.02E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS11870 1c77e4cc3abf8bbc186a8a288baa9935 395 SUPERFAMILY SSF51905 271 385 1.02E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A6A12_RS11870 1c77e4cc3abf8bbc186a8a288baa9935 395 TIGRFAM TIGR01984 UbiH: 2-polyprenyl-6-methoxyphenol 4-hydroxylase 7 391 1.3E-151 T 28-03-2018 IPR011295 2-polyprenyl-6-methoxyphenol 4-hydroxylase GO:0006744|GO:0008681 A6A12_RS11870 1c77e4cc3abf8bbc186a8a288baa9935 395 Pfam PF01494 FAD binding domain 6 341 4.3E-24 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 A6A12_RS07385 ca5278e9ad3cb4acbda47e93ccf0af94 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 220 1.6E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS07385 ca5278e9ad3cb4acbda47e93ccf0af94 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 421 435 1.6E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS07385 ca5278e9ad3cb4acbda47e93ccf0af94 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 381 397 1.6E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS07385 ca5278e9ad3cb4acbda47e93ccf0af94 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 224 237 1.6E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS07385 ca5278e9ad3cb4acbda47e93ccf0af94 466 Gene3D G3DSA:2.40.50.140 8 109 3.8E-18 T 28-03-2018 A6A12_RS07385 ca5278e9ad3cb4acbda47e93ccf0af94 466 Pfam PF01336 OB-fold nucleic acid binding domain 20 99 6.9E-11 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A6A12_RS07385 ca5278e9ad3cb4acbda47e93ccf0af94 466 Gene3D G3DSA:3.30.930.10 128 462 3.0E-92 T 28-03-2018 A6A12_RS07385 ca5278e9ad3cb4acbda47e93ccf0af94 466 SUPERFAMILY SSF55681 96 464 8.23E-95 T 28-03-2018 A6A12_RS07385 ca5278e9ad3cb4acbda47e93ccf0af94 466 SUPERFAMILY SSF50249 15 101 1.24E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS07385 ca5278e9ad3cb4acbda47e93ccf0af94 466 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 5 466 7.1E-206 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A6A12_RS07385 ca5278e9ad3cb4acbda47e93ccf0af94 466 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 460 8.6E-80 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A6A12_RS07385 ca5278e9ad3cb4acbda47e93ccf0af94 466 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 6 466 45.919 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A6A12_RS07765 c269882a85b3062147335ce75d55a7ac 155 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 12 135 8.3E-31 T 28-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN A6A12_RS07765 c269882a85b3062147335ce75d55a7ac 155 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 7 142 7.6E-31 T 28-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN A6A12_RS06705 025f6fbd3f6b456699879b133051fbd7 58 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 6 45 3.7E-14 T 28-03-2018 IPR008621 Cbb3-type cytochrome oxidase component A6A12_RS04245 745e8a5a77464f78249a2c61b9111f72 383 Pfam PF00534 Glycosyl transferases group 1 194 356 2.8E-17 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 A6A12_RS04245 745e8a5a77464f78249a2c61b9111f72 383 SUPERFAMILY SSF53756 30 368 7.46E-41 T 28-03-2018 A6A12_RS04245 745e8a5a77464f78249a2c61b9111f72 383 Gene3D G3DSA:3.40.50.2000 154 364 5.5E-25 T 28-03-2018 A6A12_RS04245 745e8a5a77464f78249a2c61b9111f72 383 Pfam PF13439 Glycosyltransferase Family 4 61 179 5.3E-9 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A6A12_RS03380 d7bdf07f22397c8c7bc128663019abd8 304 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 301 39.535 T 28-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 A6A12_RS03380 d7bdf07f22397c8c7bc128663019abd8 304 Pfam PF04381 Putative exonuclease, RdgC 1 298 4.8E-125 T 28-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 A6A12_RS09890 6be948ca7478f6ca94a90cffe07a07cd 258 Pfam PF13614 AAA domain 3 180 2.4E-50 T 28-03-2018 IPR025669 AAA domain A6A12_RS09890 6be948ca7478f6ca94a90cffe07a07cd 258 PIRSF PIRSF009320 1 74 9.1E-14 T 28-03-2018 A6A12_RS09890 6be948ca7478f6ca94a90cffe07a07cd 258 PIRSF PIRSF009320 102 240 1.4E-7 T 28-03-2018 A6A12_RS09890 6be948ca7478f6ca94a90cffe07a07cd 258 Gene3D G3DSA:3.40.50.300 3 256 2.1E-51 T 28-03-2018 A6A12_RS09890 6be948ca7478f6ca94a90cffe07a07cd 258 SUPERFAMILY SSF52540 1 252 7.96E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS04280 be6c3d1fd9de6525b5359aaf82316a40 438 Pfam PF04932 O-Antigen ligase 217 356 2.1E-17 T 28-03-2018 IPR007016 O-antigen ligase-related A6A12_RS12845 f540dc3bb20544b3dfc7e02b92f7936d 205 Gene3D G3DSA:1.10.10.10 1 72 9.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS12845 f540dc3bb20544b3dfc7e02b92f7936d 205 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 46 2.3E-7 T 28-03-2018 A6A12_RS12845 f540dc3bb20544b3dfc7e02b92f7936d 205 SUPERFAMILY SSF46785 6 183 1.59E-36 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS10690 6b3c704903a638c280c66c5a8b3910e2 377 Pfam PF16538 Flagellar assembly protein T, C-terminal domain 299 375 1.1E-28 T 28-03-2018 IPR032388 Flagellar assembly protein T, C-terminal A6A12_RS10690 6b3c704903a638c280c66c5a8b3910e2 377 Pfam PF16548 Flagellar assembly protein T, N-terminal domain 24 110 8.8E-24 T 28-03-2018 IPR032370 Flagellar assembly protein T, N-terminal A6A12_RS10690 6b3c704903a638c280c66c5a8b3910e2 377 Gene3D G3DSA:3.40.50.10070 116 266 5.0E-6 T 28-03-2018 A6A12_RS10690 6b3c704903a638c280c66c5a8b3910e2 377 Pfam PF16539 Flagellar assembly protein T, middle domain 115 256 1.5E-42 T 28-03-2018 IPR032386 Flagellar assembly protein T, middle domain A6A12_RS05900 e17702ed781694e0ebf4fe3fd7784a7b 130 Pfam PF11042 Protein of unknown function (DUF2750) 23 122 3.1E-36 T 28-03-2018 IPR021284 Protein of unknown function DUF2750 A6A12_RS07285 322b5a7b61061e09788ae7ce8a15b72d 473 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 35 463 2.2E-79 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A6A12_RS07285 322b5a7b61061e09788ae7ce8a15b72d 473 Pfam PF00939 Sodium:sulfate symporter transmembrane region 6 463 2.4E-48 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 A6A12_RS07285 322b5a7b61061e09788ae7ce8a15b72d 473 PIRSF PIRSF002457 2 473 1.6E-114 T 28-03-2018 IPR030676 Citrate carrier CitT-related A6A12_RS09455 5de88cdbea872ecdcd97740a3fdbae34 161 SUPERFAMILY SSF54593 1 153 2.01E-26 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A6A12_RS09455 5de88cdbea872ecdcd97740a3fdbae34 161 Gene3D G3DSA:3.10.180.10 1 153 3.6E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A6A12_RS09455 5de88cdbea872ecdcd97740a3fdbae34 161 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 147 3.1E-16 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain A6A12_RS09455 5de88cdbea872ecdcd97740a3fdbae34 161 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 A6A12_RS06075 98e8ab5ed26696ff3eb89a4d61abf9a9 158 Gene3D G3DSA:3.10.450.40 93 147 8.0E-8 T 28-03-2018 A6A12_RS13255 8c8e03294748c113a37fc9751a63e8b6 232 Pfam PF11102 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF 17 220 8.6E-58 T 28-03-2018 IPR021308 Group 4 capsule polysaccharide formation lipoprotein GfcB A6A12_RS13255 8c8e03294748c113a37fc9751a63e8b6 232 SUPERFAMILY SSF159270 21 227 1.57E-58 T 28-03-2018 IPR023373 YmcC-like domain A6A12_RS13255 8c8e03294748c113a37fc9751a63e8b6 232 Gene3D G3DSA:2.40.360.10 20 231 7.8E-59 T 28-03-2018 IPR023373 YmcC-like domain A6A12_RS00415 6ccc8bbb1b32b0c116ec3b027ab3c5a3 201 Gene3D G3DSA:3.40.1710.10 23 144 3.7E-4 T 28-03-2018 A6A12_RS00415 6ccc8bbb1b32b0c116ec3b027ab3c5a3 201 Pfam PF03942 DTW domain 7 186 3.0E-46 T 28-03-2018 IPR005636 DTW A6A12_RS00415 6ccc8bbb1b32b0c116ec3b027ab3c5a3 201 SMART SM01144 3 194 2.7E-50 T 28-03-2018 IPR005636 DTW A6A12_RS14085 52d51041dcb62045efc134de835c97ed 78 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 47 1.6E-21 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A6A12_RS14085 52d51041dcb62045efc134de835c97ed 78 Pfam PF02416 mttA/Hcf106 family 4 50 7.7E-13 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 A6A12_RS14085 52d51041dcb62045efc134de835c97ed 78 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 73 25.558 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 A6A12_RS06585 0da535570fe21247cf4160d58e64baf5 157 SUPERFAMILY SSF55781 5 144 6.38E-39 T 28-03-2018 IPR029016 GAF domain-like A6A12_RS06585 0da535570fe21247cf4160d58e64baf5 157 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 89 106 - T 28-03-2018 IPR000614 Free Met sulfoxide reductase conserved site A6A12_RS06585 0da535570fe21247cf4160d58e64baf5 157 Gene3D G3DSA:3.30.450.40 2 151 1.3E-21 T 28-03-2018 IPR029016 GAF domain-like A6A12_RS06585 0da535570fe21247cf4160d58e64baf5 157 Pfam PF13185 GAF domain 44 137 2.0E-9 T 28-03-2018 IPR003018 GAF domain GO:0005515 A6A12_RS07470 b9aa150ef45c390c3ecb513600f8b07a 158 SUPERFAMILY SSF46785 5 140 2.5E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS07470 b9aa150ef45c390c3ecb513600f8b07a 158 Gene3D G3DSA:1.10.10.10 1 145 1.8E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS07470 b9aa150ef45c390c3ecb513600f8b07a 158 SMART SM00347 24 124 2.1E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A6A12_RS07470 b9aa150ef45c390c3ecb513600f8b07a 158 Pfam PF01047 MarR family 31 89 4.9E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A6A12_RS06185 e139cc740428369b914cddafdf8dcfea 760 SUPERFAMILY SSF51998 222 738 3.05E-165 T 28-03-2018 A6A12_RS06185 e139cc740428369b914cddafdf8dcfea 760 SUPERFAMILY SSF48168 10 221 1.24E-72 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A6A12_RS06185 e139cc740428369b914cddafdf8dcfea 760 Gene3D G3DSA:3.20.70.20 122 739 3.6E-147 T 28-03-2018 A6A12_RS06185 e139cc740428369b914cddafdf8dcfea 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 610 637 1.8E-37 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A6A12_RS06185 e139cc740428369b914cddafdf8dcfea 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 433 444 1.8E-37 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A6A12_RS06185 e139cc740428369b914cddafdf8dcfea 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 298 317 1.8E-37 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A6A12_RS06185 e139cc740428369b914cddafdf8dcfea 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 473 496 1.8E-37 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A6A12_RS06185 e139cc740428369b914cddafdf8dcfea 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 539 562 1.8E-37 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A6A12_RS06185 e139cc740428369b914cddafdf8dcfea 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 511 533 1.8E-37 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A6A12_RS06185 e139cc740428369b914cddafdf8dcfea 760 Pfam PF03477 ATP cone domain 6 92 1.8E-18 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A6A12_RS06185 e139cc740428369b914cddafdf8dcfea 760 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 145 735 3.7E-174 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A6A12_RS06185 e139cc740428369b914cddafdf8dcfea 760 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 142 219 4.2E-11 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A6A12_RS06185 e139cc740428369b914cddafdf8dcfea 760 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 599 621 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A6A12_RS06185 e139cc740428369b914cddafdf8dcfea 760 Pfam PF02867 Ribonucleotide reductase, barrel domain 223 731 4.2E-120 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A6A12_RS01980 37988c88aa83cdc64686aa77e19be525 300 Gene3D G3DSA:1.10.10.10 2 91 3.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS01980 37988c88aa83cdc64686aa77e19be525 300 Gene3D G3DSA:3.40.190.10 176 265 6.6E-15 T 28-03-2018 A6A12_RS01980 37988c88aa83cdc64686aa77e19be525 300 SUPERFAMILY SSF46785 3 88 5.05E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS01980 37988c88aa83cdc64686aa77e19be525 300 SUPERFAMILY SSF53850 89 296 4.16E-29 T 28-03-2018 A6A12_RS01980 37988c88aa83cdc64686aa77e19be525 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.7E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 A6A12_RS01980 37988c88aa83cdc64686aa77e19be525 300 Pfam PF03466 LysR substrate binding domain 88 293 4.0E-26 T 28-03-2018 IPR005119 LysR, substrate-binding A6A12_RS01980 37988c88aa83cdc64686aa77e19be525 300 Gene3D G3DSA:3.40.190.10 94 175 8.4E-9 T 28-03-2018 A6A12_RS06770 bbe13335ae6d02bc7274fc1471f8a806 286 Gene3D G3DSA:1.10.3720.10 10 285 4.8E-46 T 28-03-2018 A6A12_RS06770 bbe13335ae6d02bc7274fc1471f8a806 286 SUPERFAMILY SSF161098 10 275 2.62E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS06770 bbe13335ae6d02bc7274fc1471f8a806 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 283 3.9E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS11930 c4738abc983e4422f1c416d8443b59b7 177 Gene3D G3DSA:1.20.144.10 19 175 4.0E-27 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A6A12_RS11930 c4738abc983e4422f1c416d8443b59b7 177 SUPERFAMILY SSF48317 7 175 1.83E-36 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A6A12_RS11930 c4738abc983e4422f1c416d8443b59b7 177 Pfam PF01569 PAP2 superfamily 66 174 9.0E-20 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A6A12_RS11930 c4738abc983e4422f1c416d8443b59b7 177 SMART SM00014 64 170 3.6E-8 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A6A12_RS11760 8a08592cab5b2b79504df0f594e14553 265 SUPERFAMILY SSF101386 139 238 1.8E-24 T 28-03-2018 A6A12_RS11760 8a08592cab5b2b79504df0f594e14553 265 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 172 230 2.6E-7 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A6A12_RS11760 8a08592cab5b2b79504df0f594e14553 265 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 28 101 2.2E-28 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A6A12_RS11760 8a08592cab5b2b79504df0f594e14553 265 TIGRFAM TIGR00444 mazG: MazG family protein 11 260 7.1E-105 T 28-03-2018 IPR011551 NTP pyrophosphohydrolase MazG A6A12_RS11760 8a08592cab5b2b79504df0f594e14553 265 SUPERFAMILY SSF101386 3 105 8.83E-26 T 28-03-2018 A6A12_RS11760 8a08592cab5b2b79504df0f594e14553 265 Gene3D G3DSA:1.10.287.1080 140 265 1.3E-25 T 28-03-2018 A6A12_RS11760 8a08592cab5b2b79504df0f594e14553 265 Gene3D G3DSA:1.10.287.1080 2 126 1.5E-39 T 28-03-2018 A6A12_RS10505 c9dad3c4ecd9f8d5417dfde1ec94d46a 269 Pfam PF13371 Tetratricopeptide repeat 187 259 1.1E-23 T 28-03-2018 A6A12_RS10505 c9dad3c4ecd9f8d5417dfde1ec94d46a 269 SUPERFAMILY SSF48452 190 252 8.43E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS10505 c9dad3c4ecd9f8d5417dfde1ec94d46a 269 Gene3D G3DSA:1.25.40.10 10 263 1.2E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS10505 c9dad3c4ecd9f8d5417dfde1ec94d46a 269 Pfam PF13369 Transglutaminase-like superfamily 33 184 2.0E-44 T 28-03-2018 IPR032698 Protein SirB1, N-terminal Reactome: R-HSA-8951664|Reactome: R-HSA-983168 A6A12_RS10990 4f4dedcf73ec6071b45183f6b132049e 154 Pfam PF00156 Phosphoribosyl transferase domain 32 145 6.3E-13 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A6A12_RS10990 4f4dedcf73ec6071b45183f6b132049e 154 Gene3D G3DSA:3.40.50.2020 1 152 1.9E-25 T 28-03-2018 A6A12_RS10990 4f4dedcf73ec6071b45183f6b132049e 154 SUPERFAMILY SSF53271 5 147 2.56E-27 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like A6A12_RS10990 4f4dedcf73ec6071b45183f6b132049e 154 Hamap MF_01903 Xanthine phosphoribosyltransferase [gpt]. 1 153 37.3 T 28-03-2018 IPR023747 Xanthine-guanine phosphoribosyltransferase GO:0000310 KEGG: 00230+2.4.2.22 A6A12_RS03650 7612f71c018f1b1b26a024eb12f47b9f 248 Pfam PF07071 KDGP aldolase 8 224 8.3E-102 T 28-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A6A12_RS03650 7612f71c018f1b1b26a024eb12f47b9f 248 Gene3D G3DSA:3.20.20.70 4 245 1.5E-112 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS03650 7612f71c018f1b1b26a024eb12f47b9f 248 SUPERFAMILY SSF51569 61 204 1.15E-5 T 28-03-2018 A6A12_RS03650 7612f71c018f1b1b26a024eb12f47b9f 248 TIGRFAM TIGR03581 EF_0839: conserved hypothetical protein EF_0839/AHA_3917 8 243 1.4E-112 T 28-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 A6A12_RS10465 3502dde3c9e5cd3f0484b86f59240fcc 116 SUPERFAMILY SSF52833 2 116 1.6E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS10465 3502dde3c9e5cd3f0484b86f59240fcc 116 Pfam PF03960 ArsC family 6 115 7.3E-22 T 28-03-2018 IPR006660 Arsenate reductase-like A6A12_RS10465 3502dde3c9e5cd3f0484b86f59240fcc 116 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 3 116 6.9E-46 T 28-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 A6A12_RS10465 3502dde3c9e5cd3f0484b86f59240fcc 116 Gene3D G3DSA:3.40.30.10 1 116 2.2E-35 T 28-03-2018 A6A12_RS10930 d7431eba182b10c6faaf6ece0696078b 167 PIRSF PIRSF006162 6 166 2.4E-53 T 28-03-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 A6A12_RS10930 d7431eba182b10c6faaf6ece0696078b 167 Gene3D G3DSA:1.10.3760.10 45 161 4.9E-39 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A6A12_RS10930 d7431eba182b10c6faaf6ece0696078b 167 SUPERFAMILY SSF101307 9 159 7.06E-48 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A6A12_RS10930 d7431eba182b10c6faaf6ece0696078b 167 Pfam PF04608 Phosphatidylglycerophosphatase A 15 158 2.1E-51 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A6A12_RS12240 56707dd1f87ec8e6deec1fef07072b5a 123 SUPERFAMILY SSF110857 9 122 1.02E-31 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like A6A12_RS12240 56707dd1f87ec8e6deec1fef07072b5a 123 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 13 120 4.6E-24 T 28-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like A6A12_RS12240 56707dd1f87ec8e6deec1fef07072b5a 123 Gene3D G3DSA:3.10.490.10 5 122 3.3E-33 T 28-03-2018 A6A12_RS08945 5940cf1d12edad0d32ec0ad66087bcef 336 Gene3D G3DSA:2.40.128.140 22 333 1.4E-84 T 28-03-2018 IPR018707 Protein of unknown function DUF2219 A6A12_RS08945 5940cf1d12edad0d32ec0ad66087bcef 336 Pfam PF09982 Uncharacterized protein conserved in bacteria (DUF2219) 36 333 4.5E-84 T 28-03-2018 IPR018707 Protein of unknown function DUF2219 A6A12_RS00505 0470e80c0b2b000150143e403d219743 380 Gene3D G3DSA:3.30.30.60 127 164 0.0096 T 28-03-2018 IPR028991 D-lysine 5,6-aminomutase beta subunit KamE, N-terminal GO:0046983 A6A12_RS00505 0470e80c0b2b000150143e403d219743 380 Pfam PF14882 Phage-integrase repeat unit 32 78 3.2E-12 T 28-03-2018 IPR028229 Phage-integrase repeat unit A6A12_RS00505 0470e80c0b2b000150143e403d219743 380 Pfam PF14882 Phage-integrase repeat unit 95 144 1.9E-17 T 28-03-2018 IPR028229 Phage-integrase repeat unit A6A12_RS00505 0470e80c0b2b000150143e403d219743 380 Pfam PF14882 Phage-integrase repeat unit 221 270 1.6E-18 T 28-03-2018 IPR028229 Phage-integrase repeat unit A6A12_RS00505 0470e80c0b2b000150143e403d219743 380 Pfam PF14882 Phage-integrase repeat unit 283 331 1.2E-17 T 28-03-2018 IPR028229 Phage-integrase repeat unit A6A12_RS00505 0470e80c0b2b000150143e403d219743 380 Pfam PF14882 Phage-integrase repeat unit 348 368 0.013 T 28-03-2018 IPR028229 Phage-integrase repeat unit A6A12_RS00505 0470e80c0b2b000150143e403d219743 380 Pfam PF14882 Phage-integrase repeat unit 158 207 7.3E-18 T 28-03-2018 IPR028229 Phage-integrase repeat unit A6A12_RS12150 228080dfae4ee46c5e77291d43d1cc4e 166 Pfam PF03968 OstA-like protein 30 141 3.8E-29 T 28-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal A6A12_RS12150 228080dfae4ee46c5e77291d43d1cc4e 166 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 20 160 4.0E-46 T 28-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 A6A12_RS12150 228080dfae4ee46c5e77291d43d1cc4e 166 Gene3D G3DSA:2.60.450.10 20 157 1.5E-26 T 28-03-2018 A6A12_RS12150 228080dfae4ee46c5e77291d43d1cc4e 166 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 1 160 23.565 T 28-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 A6A12_RS01685 08117ad35c2a651f54b81e9345558b72 277 Gene3D G3DSA:3.60.110.10 2 271 3.5E-76 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A6A12_RS01685 08117ad35c2a651f54b81e9345558b72 277 Pfam PF00795 Carbon-nitrogen hydrolase 3 256 2.7E-54 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A6A12_RS01685 08117ad35c2a651f54b81e9345558b72 277 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 149 169 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site A6A12_RS01685 08117ad35c2a651f54b81e9345558b72 277 SUPERFAMILY SSF56317 3 263 1.07E-78 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 A6A12_RS06865 ebacc7b7151f24ea2428a65e8d29cb49 691 Gene3D G3DSA:1.20.120.570 41 182 0.17 T 28-03-2018 A6A12_RS06865 ebacc7b7151f24ea2428a65e8d29cb49 691 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 502 655 1.8E-40 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS06865 ebacc7b7151f24ea2428a65e8d29cb49 691 SMART SM00283 414 689 6.3E-41 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 A6A12_RS06865 ebacc7b7151f24ea2428a65e8d29cb49 691 SUPERFAMILY SSF58104 381 689 1.07E-59 T 28-03-2018 A6A12_RS06865 ebacc7b7151f24ea2428a65e8d29cb49 691 Gene3D G3DSA:1.10.287.950 454 691 1.0E-45 T 28-03-2018 A6A12_RS12980 fbe58449b05934ada1da08f3dea92e78 70 Gene3D G3DSA:2.40.50.140 1 70 5.9E-27 T 28-03-2018 A6A12_RS12980 fbe58449b05934ada1da08f3dea92e78 70 SUPERFAMILY SSF50249 4 69 2.14E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold A6A12_RS12980 fbe58449b05934ada1da08f3dea92e78 70 PRINTS PR00050 Cold shock protein signature 28 37 1.5E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A6A12_RS12980 fbe58449b05934ada1da08f3dea92e78 70 PRINTS PR00050 Cold shock protein signature 7 22 1.5E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A6A12_RS12980 fbe58449b05934ada1da08f3dea92e78 70 PRINTS PR00050 Cold shock protein signature 43 61 1.5E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A6A12_RS12980 fbe58449b05934ada1da08f3dea92e78 70 SMART SM00357 6 70 2.2E-29 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 A6A12_RS12980 fbe58449b05934ada1da08f3dea92e78 70 Pfam PF00313 'Cold-shock' DNA-binding domain 6 69 5.0E-28 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 A6A12_RS12980 fbe58449b05934ada1da08f3dea92e78 70 PIRSF PIRSF002599 1 70 2.0E-24 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 A6A12_RS10435 01805aa693be57d45cb693b5cba7e5b7 563 Pfam PF10088 Uncharacterised protein conserved in bacteria (DUF2326) 444 561 4.3E-15 T 28-03-2018 IPR018760 Protein of unknown function DUF2326 A6A12_RS10435 01805aa693be57d45cb693b5cba7e5b7 563 Gene3D G3DSA:3.40.50.300 1 305 1.0E-5 T 28-03-2018 A6A12_RS06825 c5a2db5e96c67828548f4b76354f6781 698 SUPERFAMILY SSF161098 150 411 1.03E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS06825 c5a2db5e96c67828548f4b76354f6781 698 Gene3D G3DSA:1.10.3720.10 432 692 4.0E-32 T 28-03-2018 A6A12_RS06825 c5a2db5e96c67828548f4b76354f6781 698 Gene3D G3DSA:1.10.3720.10 146 413 1.8E-35 T 28-03-2018 A6A12_RS06825 c5a2db5e96c67828548f4b76354f6781 698 ProSitePatterns PS00210 Arthropod hemocyanins / insect LSPs signature 2. 16 24 - T 28-03-2018 IPR013788 Hemocyanin/hexamerin A6A12_RS06825 c5a2db5e96c67828548f4b76354f6781 698 SUPERFAMILY SSF161098 440 680 9.35E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS06825 c5a2db5e96c67828548f4b76354f6781 698 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 506 684 9.2E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS06825 c5a2db5e96c67828548f4b76354f6781 698 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 214 405 2.4E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS01400 070ea7a9e7d0a7a6e505bd40a72fbc4b 254 Pfam PF04338 Protein of unknown function, DUF481 39 254 7.7E-49 T 28-03-2018 IPR007433 Protein of unknown function DUF481 A6A12_RS11185 cae43cbd6faa21e1714ae98d5d272347 338 Pfam PF03595 Voltage-dependent anion channel 19 308 7.2E-30 T 28-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 A6A12_RS07870 e8fa964c672d485843af0f984eab9f4b 78 Gene3D G3DSA:1.10.10.10 5 66 2.9E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS02795 2242c454b2ea15900e36c12c428a326d 342 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS02795 2242c454b2ea15900e36c12c428a326d 342 Pfam PF00005 ABC transporter 20 164 2.3E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS02795 2242c454b2ea15900e36c12c428a326d 342 SUPERFAMILY SSF52540 5 242 3.55E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS02795 2242c454b2ea15900e36c12c428a326d 342 Gene3D G3DSA:3.40.50.300 1 306 1.3E-74 T 28-03-2018 A6A12_RS02795 2242c454b2ea15900e36c12c428a326d 342 SUPERFAMILY SSF50331 263 342 1.53E-8 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal A6A12_RS02795 2242c454b2ea15900e36c12c428a326d 342 SMART SM00382 29 214 8.3E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS02795 2242c454b2ea15900e36c12c428a326d 342 Pfam PF08402 TOBE domain 276 342 3.0E-7 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 A6A12_RS12580 e0bc05dfabdf87a678918659a3033675 68 Gene3D G3DSA:1.10.10.610 1 68 8.8E-33 T 28-03-2018 IPR010648 Uncharacterised protein family UPF0270 A6A12_RS12580 e0bc05dfabdf87a678918659a3033675 68 SUPERFAMILY SSF118001 1 67 8.5E-27 T 28-03-2018 IPR010648 Uncharacterised protein family UPF0270 A6A12_RS12580 e0bc05dfabdf87a678918659a3033675 68 ProDom PD026997 UPF0270 YHEU SO0879 3D-STRUCTURE LYASE PLU0398 YPO0179/Y3960/YP0178 ENOLASE HD0737 PSPTO1630 1 68 3.0E-17 T 28-03-2018 IPR010648 Uncharacterised protein family UPF0270 A6A12_RS12580 e0bc05dfabdf87a678918659a3033675 68 Pfam PF06794 Uncharacterised protein family (UPF0270) 1 67 9.2E-34 T 28-03-2018 IPR010648 Uncharacterised protein family UPF0270 A6A12_RS12580 e0bc05dfabdf87a678918659a3033675 68 PIRSF PIRSF006169 1 68 1.2E-34 T 28-03-2018 IPR010648 Uncharacterised protein family UPF0270 A6A12_RS05945 25370ebc40a0f5556fc1176578e236dd 77 Pfam PF06667 Phage shock protein B 3 74 1.3E-32 T 28-03-2018 IPR009554 Phage shock protein B GO:0006355|GO:0009271 A6A12_RS05945 25370ebc40a0f5556fc1176578e236dd 77 TIGRFAM TIGR02976 phageshock_pspB: phage shock protein B 1 74 1.1E-33 T 28-03-2018 IPR009554 Phage shock protein B GO:0006355|GO:0009271 A6A12_RS03310 77a3bc691e17a7dbb7583c90191883fd 241 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 1 240 36.985 T 28-03-2018 IPR017689 Outer membrane protein assembly factor BamD A6A12_RS03310 77a3bc691e17a7dbb7583c90191883fd 241 Pfam PF13525 Outer membrane lipoprotein 26 234 1.7E-79 T 28-03-2018 A6A12_RS03310 77a3bc691e17a7dbb7583c90191883fd 241 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 8 239 2.6E-78 T 28-03-2018 IPR017689 Outer membrane protein assembly factor BamD A6A12_RS03310 77a3bc691e17a7dbb7583c90191883fd 241 SUPERFAMILY SSF48452 30 119 1.52E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS03310 77a3bc691e17a7dbb7583c90191883fd 241 Gene3D G3DSA:1.25.40.10 24 241 1.1E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS06665 23ae1171f093ae6fb01e91288de0049f 149 Pfam PF17414 MatP C-terminal ribbon-helix-helix domain 88 147 5.8E-27 T 28-03-2018 IPR035375 MatP, C-terminal ribbon-helix-helix domain A6A12_RS06665 23ae1171f093ae6fb01e91288de0049f 149 Pfam PF06303 MatP N-terminal domain 2 85 5.8E-40 T 28-03-2018 IPR035087 MatP, N-terminal A6A12_RS06665 23ae1171f093ae6fb01e91288de0049f 149 Hamap MF_01073 Macrodomain Ter protein [matP]. 1 148 28.632 T 28-03-2018 IPR009390 Macrodomain Ter protein, MatP GO:0043565 A6A12_RS06665 23ae1171f093ae6fb01e91288de0049f 149 ProDom PD033720 UPF0268 YCBG DEHYDROGENASE PM0482 PBPRA1775 PLU1774 YPO1433/Y2737/YP0877 VV1664 HI1323 HD0178 1 134 6.0E-61 T 28-03-2018 IPR009390 Macrodomain Ter protein, MatP GO:0043565 A6A12_RS12215 8986045788aba7ec84907225346a56af 209 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 8 201 1.8E-57 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 A6A12_RS12215 8986045788aba7ec84907225346a56af 209 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 6 203 35.222 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 A6A12_RS12215 8986045788aba7ec84907225346a56af 209 Pfam PF02441 Flavoprotein 7 182 2.2E-25 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A6A12_RS12215 8986045788aba7ec84907225346a56af 209 SUPERFAMILY SSF52507 6 202 2.62E-56 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A6A12_RS12215 8986045788aba7ec84907225346a56af 209 Gene3D G3DSA:3.40.50.1950 6 208 1.1E-49 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A6A12_RS02400 c2d5294b42ce1c0d1c0f3345928c258c 248 Pfam PF01975 Survival protein SurE 3 181 1.1E-59 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A6A12_RS02400 c2d5294b42ce1c0d1c0f3345928c258c 248 Gene3D G3DSA:3.40.1210.10 1 247 2.5E-85 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A6A12_RS02400 c2d5294b42ce1c0d1c0f3345928c258c 248 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 247 41.073 T 28-03-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A6A12_RS02400 c2d5294b42ce1c0d1c0f3345928c258c 248 SUPERFAMILY SSF64167 1 246 1.28E-84 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A6A12_RS02400 c2d5294b42ce1c0d1c0f3345928c258c 248 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 232 6.6E-70 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A6A12_RS00575 756655cee95c1fab713e7736dcd9c1cb 184 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 19 178 23.752 T 28-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 A6A12_RS00575 756655cee95c1fab713e7736dcd9c1cb 184 Gene3D G3DSA:3.40.1410.10 10 178 1.2E-43 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A6A12_RS00575 756655cee95c1fab713e7736dcd9c1cb 184 SUPERFAMILY SSF64288 13 178 1.2E-45 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain A6A12_RS00575 756655cee95c1fab713e7736dcd9c1cb 184 Pfam PF04345 Chorismate lyase 16 183 1.7E-55 T 28-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 A6A12_RS02905 52f91049274150b5cc072f3c8427e22b 480 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 340 354 2.4E-27 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A6A12_RS02905 52f91049274150b5cc072f3c8427e22b 480 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 59 78 2.4E-27 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A6A12_RS02905 52f91049274150b5cc072f3c8427e22b 480 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 281 303 2.4E-27 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A6A12_RS02905 52f91049274150b5cc072f3c8427e22b 480 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 355 369 2.4E-27 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A6A12_RS02905 52f91049274150b5cc072f3c8427e22b 480 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 419 432 2.4E-27 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A6A12_RS02905 52f91049274150b5cc072f3c8427e22b 480 Gene3D G3DSA:3.40.710.10 26 474 1.6E-32 T 28-03-2018 A6A12_RS02905 52f91049274150b5cc072f3c8427e22b 480 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 32 463 1.8E-105 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A6A12_RS02905 52f91049274150b5cc072f3c8427e22b 480 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 56 441 4.6E-104 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 A6A12_RS02905 52f91049274150b5cc072f3c8427e22b 480 SUPERFAMILY SSF56601 27 461 6.19E-85 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like A6A12_RS04605 c3ff89eeab1cb24ade8ebde6395dbfc4 163 Pfam PF02674 Colicin V production protein 4 142 1.2E-36 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 A6A12_RS00435 719be34c36620364d449620ae28a230f 205 PIRSF PIRSF006324 1 205 5.1E-57 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A6A12_RS00435 719be34c36620364d449620ae28a230f 205 Pfam PF01810 LysE type translocator 15 202 7.8E-38 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A6A12_RS06500 841b3fc04a75d25258e4f47baa6a8e57 222 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 19 216 1.4E-44 T 28-03-2018 IPR006214 Bax inhibitor 1-related A6A12_RS00365 9056796fc5d4bc5c4d678ced0d2578b1 253 Gene3D G3DSA:3.40.50.10090 1 116 6.0E-18 T 28-03-2018 A6A12_RS00365 9056796fc5d4bc5c4d678ced0d2578b1 253 SUPERFAMILY SSF69618 1 241 2.09E-49 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A6A12_RS00365 9056796fc5d4bc5c4d678ced0d2578b1 253 Gene3D G3DSA:3.40.50.10090 117 244 1.1E-13 T 28-03-2018 A6A12_RS00365 9056796fc5d4bc5c4d678ced0d2578b1 253 Pfam PF02602 Uroporphyrinogen-III synthase HemD 14 223 1.6E-30 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 A6A12_RS11010 5d69406066a68e37ca689fbc4bd47f2e 301 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 286 6.6E-87 T 28-03-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 A6A12_RS11010 5d69406066a68e37ca689fbc4bd47f2e 301 Hamap MF_01552 Ribosomal protein S6--L-glutamate ligase [rimK]. 1 295 53.446 T 28-03-2018 IPR023533 Ribosomal protein S6--L-glutamate ligase RimK A6A12_RS11010 5d69406066a68e37ca689fbc4bd47f2e 301 Gene3D G3DSA:3.30.1490.20 115 170 6.7E-11 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 A6A12_RS11010 5d69406066a68e37ca689fbc4bd47f2e 301 Gene3D G3DSA:3.40.50.20 1 114 4.4E-36 T 28-03-2018 A6A12_RS11010 5d69406066a68e37ca689fbc4bd47f2e 301 SUPERFAMILY SSF56059 98 288 5.77E-49 T 28-03-2018 A6A12_RS11010 5d69406066a68e37ca689fbc4bd47f2e 301 Pfam PF08443 RimK-like ATP-grasp domain 98 286 2.0E-67 T 28-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 A6A12_RS11010 5d69406066a68e37ca689fbc4bd47f2e 301 Gene3D G3DSA:3.30.470.20 171 277 3.4E-34 T 28-03-2018 A6A12_RS01545 d0ada71fbb02cf6749acb29000b84961 597 Pfam PF11846 Virulence factor membrane-bound polymerase, C-terminal 399 587 1.9E-66 T 28-03-2018 IPR021797 Virulence factor membrane-bound polymerase, C-terminal A6A12_RS01545 d0ada71fbb02cf6749acb29000b84961 597 Pfam PF15864 Protein glycosylation ligase 185 210 2.0E-11 T 28-03-2018 IPR031726 Protein glycosylation ligase domain A6A12_RS01545 d0ada71fbb02cf6749acb29000b84961 597 Pfam PF04932 O-Antigen ligase 232 377 6.9E-16 T 28-03-2018 IPR007016 O-antigen ligase-related A6A12_RS11340 f78a930a43b2ee14cbb32e3f7596a5f8 61 Pfam PF12065 Protein of unknown function (DUF3545) 3 59 3.7E-24 T 28-03-2018 IPR021932 Protein of unknown function DUF3545 A6A12_RS05505 1541c3a6ea804888ad417b9a756ac367 240 Gene3D G3DSA:3.40.50.620 51 188 6.0E-19 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS05505 1541c3a6ea804888ad417b9a756ac367 240 Pfam PF02698 DUF218 domain 63 200 3.4E-19 T 28-03-2018 IPR003848 Domain of unknown function DUF218 A6A12_RS01555 09ef063a0937b7adab607bcc60eb0272 289 Pfam PF00483 Nucleotidyl transferase 9 265 4.0E-32 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A6A12_RS01555 09ef063a0937b7adab607bcc60eb0272 289 SUPERFAMILY SSF53448 2 271 5.42E-65 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS01555 09ef063a0937b7adab607bcc60eb0272 289 Gene3D G3DSA:3.90.550.10 3 275 1.4E-56 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS01555 09ef063a0937b7adab607bcc60eb0272 289 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 2 263 6.0E-125 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 A6A12_RS03205 c4f0c3a1383f465f3fbd8158dcdce68c 143 SUPERFAMILY SSF54534 4 142 2.36E-36 T 28-03-2018 A6A12_RS03205 c4f0c3a1383f465f3fbd8158dcdce68c 143 Gene3D G3DSA:3.10.50.40 1 143 3.0E-19 T 28-03-2018 A6A12_RS03205 c4f0c3a1383f465f3fbd8158dcdce68c 143 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 4 139 2.0E-12 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A6A12_RS04880 0ec5282038a579e655d5a4b7e9c61dbe 182 PIRSF PIRSF000232 1 182 9.2E-60 T 28-03-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like A6A12_RS04880 0ec5282038a579e655d5a4b7e9c61dbe 182 SUPERFAMILY SSF55469 1 181 4.58E-40 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A6A12_RS04880 0ec5282038a579e655d5a4b7e9c61dbe 182 Pfam PF00881 Nitroreductase family 8 161 3.8E-23 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A6A12_RS04880 0ec5282038a579e655d5a4b7e9c61dbe 182 Gene3D G3DSA:3.40.109.10 1 182 4.1E-32 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A6A12_RS05545 4f3bae312c0b6e969d0a0d68c49bf4c1 284 Gene3D G3DSA:3.40.50.10490 99 279 3.8E-34 T 28-03-2018 A6A12_RS05545 4f3bae312c0b6e969d0a0d68c49bf4c1 284 Pfam PF01380 SIS domain 124 252 1.7E-24 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A6A12_RS05545 4f3bae312c0b6e969d0a0d68c49bf4c1 284 SUPERFAMILY SSF46689 1 80 1.58E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 A6A12_RS05545 4f3bae312c0b6e969d0a0d68c49bf4c1 284 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 1.7E-29 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 A6A12_RS05545 4f3bae312c0b6e969d0a0d68c49bf4c1 284 Gene3D G3DSA:1.10.10.10 1 98 3.7E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS05545 4f3bae312c0b6e969d0a0d68c49bf4c1 284 SUPERFAMILY SSF53697 93 278 1.19E-39 T 28-03-2018 A6A12_RS10290 b4c35c2c6e82fa01d26344d50a43c434 113 Pfam PF11169 Protein of unknown function (DUF2956) 8 109 2.0E-41 T 28-03-2018 IPR021339 Protein of unknown function DUF2956 A6A12_RS09980 4a202e5a234b8561ba57c4db0a754180 292 SUPERFAMILY SSF53807 23 290 1.18E-71 T 28-03-2018 A6A12_RS09980 4a202e5a234b8561ba57c4db0a754180 292 Pfam PF01297 Zinc-uptake complex component A periplasmic 23 289 9.1E-56 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A6A12_RS09980 4a202e5a234b8561ba57c4db0a754180 292 Gene3D G3DSA:3.40.50.1980 18 173 6.5E-41 T 28-03-2018 A6A12_RS09980 4a202e5a234b8561ba57c4db0a754180 292 Gene3D G3DSA:3.40.50.1980 174 291 1.2E-25 T 28-03-2018 A6A12_RS09980 4a202e5a234b8561ba57c4db0a754180 292 PRINTS PR00690 Adhesin family signature 51 64 1.4E-5 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A6A12_RS09980 4a202e5a234b8561ba57c4db0a754180 292 PRINTS PR00690 Adhesin family signature 179 200 1.4E-5 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A6A12_RS09980 4a202e5a234b8561ba57c4db0a754180 292 PRINTS PR00690 Adhesin family signature 64 81 1.4E-5 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 A6A12_RS01535 76f0bafbab13c1ceb4f06f731478d55e 131 Gene3D G3DSA:3.10.580.10 23 131 4.8E-7 T 28-03-2018 A6A12_RS01535 76f0bafbab13c1ceb4f06f731478d55e 131 SUPERFAMILY SSF54631 22 129 3.29E-14 T 28-03-2018 A6A12_RS00980 28cee4da8f62a5b73ee56c9aeaf7a34c 217 Gene3D G3DSA:3.40.109.10 1 215 2.8E-37 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A6A12_RS00980 28cee4da8f62a5b73ee56c9aeaf7a34c 217 SUPERFAMILY SSF55469 1 216 2.09E-62 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A6A12_RS00980 28cee4da8f62a5b73ee56c9aeaf7a34c 217 Pfam PF00881 Nitroreductase family 9 193 1.3E-27 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A6A12_RS07225 4a2493746eeb03cd628aec2d07ab82ee 125 Pfam PF04320 Protein with unknown function (DUF469) 24 124 7.9E-33 T 28-03-2018 IPR007416 Protein of unknown function DUF469 A6A12_RS13630 f264debd57b2a1be53898b43da2e1e64 77 Gene3D G3DSA:1.10.10.10 31 77 1.1E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS13630 f264debd57b2a1be53898b43da2e1e64 77 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 26 75 8.7E-10 T 28-03-2018 IPR010260 DNA-binding transcriptional activator AlpA A6A12_RS03740 55e0855a74f631668363b9ab9b15ce48 224 Pfam PF11726 Inovirus Gp2 40 220 1.4E-40 T 28-03-2018 A6A12_RS14310 c21d40f0f5a9982245e112fc2e35e36a 485 PIRSF PIRSF006247 1 485 2.5E-176 T 28-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 A6A12_RS14310 c21d40f0f5a9982245e112fc2e35e36a 485 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 85 468 1.7E-117 T 28-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 A6A12_RS14310 c21d40f0f5a9982245e112fc2e35e36a 485 Pfam PF02386 Cation transport protein 39 477 8.0E-89 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A6A12_RS13195 3cf991fa5eb3ddecd25a27e7bbb2aee3 334 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 233 2.9E-56 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A6A12_RS13195 3cf991fa5eb3ddecd25a27e7bbb2aee3 334 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 5.9E-30 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A6A12_RS13195 3cf991fa5eb3ddecd25a27e7bbb2aee3 334 PRINTS PR01713 Nucleotide sugar epimerase signature 215 230 5.9E-30 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A6A12_RS13195 3cf991fa5eb3ddecd25a27e7bbb2aee3 334 PRINTS PR01713 Nucleotide sugar epimerase signature 255 270 5.9E-30 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A6A12_RS13195 3cf991fa5eb3ddecd25a27e7bbb2aee3 334 PRINTS PR01713 Nucleotide sugar epimerase signature 294 311 5.9E-30 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 A6A12_RS13195 3cf991fa5eb3ddecd25a27e7bbb2aee3 334 SUPERFAMILY SSF51735 1 333 4.3E-91 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS13195 3cf991fa5eb3ddecd25a27e7bbb2aee3 334 Gene3D G3DSA:3.90.25.10 190 334 4.1E-35 T 28-03-2018 A6A12_RS13195 3cf991fa5eb3ddecd25a27e7bbb2aee3 334 Gene3D G3DSA:3.40.50.720 2 189 1.3E-39 T 28-03-2018 A6A12_RS07305 da3fa7e5e46213b96b4feddc868bcc71 328 SUPERFAMILY SSF55073 150 307 5.96E-40 T 28-03-2018 IPR029787 Nucleotide cyclase A6A12_RS07305 da3fa7e5e46213b96b4feddc868bcc71 328 Pfam PF00990 Diguanylate cyclase, GGDEF domain 147 302 1.3E-36 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS07305 da3fa7e5e46213b96b4feddc868bcc71 328 SMART SM00267 134 306 1.1E-42 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS07305 da3fa7e5e46213b96b4feddc868bcc71 328 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 145 305 5.3E-38 T 28-03-2018 IPR000160 GGDEF domain A6A12_RS07305 da3fa7e5e46213b96b4feddc868bcc71 328 Gene3D G3DSA:3.30.70.270 140 313 6.8E-44 T 28-03-2018 A6A12_RS14445 8b3d6023b71b66d9ac02d5cfd654308d 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 217 7.7E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS14445 8b3d6023b71b66d9ac02d5cfd654308d 223 Gene3D G3DSA:1.10.3720.10 1 222 2.9E-41 T 28-03-2018 A6A12_RS14445 8b3d6023b71b66d9ac02d5cfd654308d 223 SUPERFAMILY SSF161098 13 206 2.49E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS14445 8b3d6023b71b66d9ac02d5cfd654308d 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 112 3.6E-23 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 A6A12_RS12960 8e249c86f22e5ec8a2658300ea90b2f6 165 PIRSF PIRSF034445 1 156 1.0E-18 T 28-03-2018 IPR012899 LTXXQ motif family protein GO:0042597 A6A12_RS12960 8e249c86f22e5ec8a2658300ea90b2f6 165 Pfam PF07813 LTXXQ motif family protein 43 146 3.0E-21 T 28-03-2018 IPR012899 LTXXQ motif family protein GO:0042597 A6A12_RS10390 b96fea1fbee009ddcf563d7e9ca4cf55 315 Gene3D G3DSA:3.40.50.1460 1 221 1.7E-40 T 28-03-2018 A6A12_RS10390 b96fea1fbee009ddcf563d7e9ca4cf55 315 SUPERFAMILY SSF52129 2 179 8.02E-18 T 28-03-2018 IPR029030 Caspase-like domain A6A12_RS10390 b96fea1fbee009ddcf563d7e9ca4cf55 315 Pfam PF00656 Caspase domain 2 144 5.5E-22 T 28-03-2018 A6A12_RS11595 77a37652a071cf92a7caa4e60292cbf1 189 SMART SM00749 127 189 4.2E-4 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria A6A12_RS11595 77a37652a071cf92a7caa4e60292cbf1 189 SMART SM00749 50 113 20.0 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria A6A12_RS11595 77a37652a071cf92a7caa4e60292cbf1 189 Pfam PF04972 BON domain 45 112 7.7E-10 T 28-03-2018 IPR007055 BON domain A6A12_RS11595 77a37652a071cf92a7caa4e60292cbf1 189 Pfam PF04972 BON domain 122 187 2.9E-18 T 28-03-2018 IPR007055 BON domain A6A12_RS05845 3f261652332e46591d9391e014388be0 210 Gene3D G3DSA:3.40.50.620 15 151 8.6E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS05845 3f261652332e46591d9391e014388be0 210 Pfam PF02698 DUF218 domain 26 142 6.7E-21 T 28-03-2018 IPR003848 Domain of unknown function DUF218 A6A12_RS00855 45badb0e5c48c8f05d6ed6a8e82cb6f5 306 TIGRFAM TIGR01713 typeII_sec_gspC: type II secretion system protein C 34 306 4.1E-85 T 28-03-2018 IPR001639 Type II secretion system protein C GO:0008565|GO:0015627|GO:0015628 A6A12_RS00855 45badb0e5c48c8f05d6ed6a8e82cb6f5 306 Gene3D G3DSA:2.30.42.10 133 305 2.1E-11 T 28-03-2018 A6A12_RS00855 45badb0e5c48c8f05d6ed6a8e82cb6f5 306 SUPERFAMILY SSF50156 211 305 8.22E-18 T 28-03-2018 IPR001478 PDZ domain GO:0005515 A6A12_RS00855 45badb0e5c48c8f05d6ed6a8e82cb6f5 306 Pfam PF11356 Type II secretion system protein C 36 175 5.3E-43 T 28-03-2018 IPR024961 Type II secretion system protein C, N-terminal A6A12_RS00855 45badb0e5c48c8f05d6ed6a8e82cb6f5 306 ProSitePatterns PS01141 Bacterial type II secretion system protein C signature. 244 270 - T 28-03-2018 IPR001639 Type II secretion system protein C GO:0008565|GO:0015627|GO:0015628 A6A12_RS10765 cfbd4313a215da996f7c778b3509a378 191 Pfam PF13580 SIS domain 24 146 6.6E-31 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A6A12_RS10765 cfbd4313a215da996f7c778b3509a378 191 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 190 38.089 T 28-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 A6A12_RS10765 cfbd4313a215da996f7c778b3509a378 191 Gene3D G3DSA:3.40.50.10490 1 191 1.1E-41 T 28-03-2018 A6A12_RS10765 cfbd4313a215da996f7c778b3509a378 191 SUPERFAMILY SSF53697 1 188 1.66E-52 T 28-03-2018 A6A12_RS10765 cfbd4313a215da996f7c778b3509a378 191 TIGRFAM TIGR00441 gmhA: phosphoheptose isomerase 34 187 1.8E-82 T 28-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 A6A12_RS06320 e9c0b7f8e33e249906916688811b8d99 135 SUPERFAMILY SSF54637 8 131 4.17E-26 T 28-03-2018 IPR029069 HotDog domain A6A12_RS06320 e9c0b7f8e33e249906916688811b8d99 135 Pfam PF03061 Thioesterase superfamily 50 111 1.4E-7 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A6A12_RS06320 e9c0b7f8e33e249906916688811b8d99 135 Gene3D G3DSA:3.10.129.10 5 132 2.1E-18 T 28-03-2018 A6A12_RS09585 72c47203fecd05a19b5d480c11bc07e4 202 SMART SM01144 1 191 1.9E-67 T 28-03-2018 IPR005636 DTW A6A12_RS09585 72c47203fecd05a19b5d480c11bc07e4 202 Pfam PF03942 DTW domain 3 186 3.1E-50 T 28-03-2018 IPR005636 DTW A6A12_RS03920 8c896c493ef7812f5d338c477e639e84 222 PIRSF PIRSF004525 14 222 7.1E-11 T 28-03-2018 IPR016419 Prepilin peptidase-dependent protein B, predicted A6A12_RS11890 c1e4bafe76065ecfe47baa49201fe2f2 196 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 6 188 6.8E-53 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A6A12_RS11890 c1e4bafe76065ecfe47baa49201fe2f2 196 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 6 188 7.3E-45 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A6A12_RS11890 c1e4bafe76065ecfe47baa49201fe2f2 196 PIRSF PIRSF006806 1 191 3.9E-37 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase A6A12_RS11890 c1e4bafe76065ecfe47baa49201fe2f2 196 Gene3D G3DSA:3.40.50.10420 1 196 3.5E-58 T 28-03-2018 A6A12_RS11890 c1e4bafe76065ecfe47baa49201fe2f2 196 SUPERFAMILY SSF100950 4 194 7.95E-56 T 28-03-2018 A6A12_RS03425 255cbd5daeb6cd234cafddad0a0dfcee 232 PIRSF PIRSF003107 4 224 2.7E-70 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 A6A12_RS03425 255cbd5daeb6cd234cafddad0a0dfcee 232 Gene3D G3DSA:1.20.58.220 3 115 8.1E-29 T 28-03-2018 A6A12_RS03425 255cbd5daeb6cd234cafddad0a0dfcee 232 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 10 219 1.4E-76 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 A6A12_RS03425 255cbd5daeb6cd234cafddad0a0dfcee 232 SUPERFAMILY SSF109755 10 225 5.23E-70 T 28-03-2018 A6A12_RS03425 255cbd5daeb6cd234cafddad0a0dfcee 232 Gene3D G3DSA:1.20.58.220 116 231 2.7E-26 T 28-03-2018 A6A12_RS03425 255cbd5daeb6cd234cafddad0a0dfcee 232 Pfam PF01895 PhoU domain 23 108 1.8E-22 T 28-03-2018 IPR026022 PhoU domain A6A12_RS03425 255cbd5daeb6cd234cafddad0a0dfcee 232 Pfam PF01895 PhoU domain 128 210 7.2E-16 T 28-03-2018 IPR026022 PhoU domain A6A12_RS11990 63a938904529b1852e6247e1e1442b8b 416 Pfam PF11871 Domain of unknown function (DUF3391) 4 135 9.4E-34 T 28-03-2018 IPR021812 Protein of unknown function DUF3391 A6A12_RS11990 63a938904529b1852e6247e1e1442b8b 416 Pfam PF01966 HD domain 169 289 6.8E-15 T 28-03-2018 IPR006674 HD domain A6A12_RS11990 63a938904529b1852e6247e1e1442b8b 416 SMART SM00471 163 299 1.6E-8 T 28-03-2018 IPR003607 HD/PDEase domain A6A12_RS11990 63a938904529b1852e6247e1e1442b8b 416 Gene3D G3DSA:1.10.3210.10 114 312 1.8E-30 T 28-03-2018 A6A12_RS11990 63a938904529b1852e6247e1e1442b8b 416 TIGRFAM TIGR00277 HDIG: HDIG domain 165 258 3.2E-8 T 28-03-2018 IPR006675 HDIG domain A6A12_RS11990 63a938904529b1852e6247e1e1442b8b 416 SUPERFAMILY SSF109604 158 329 2.47E-27 T 28-03-2018 A6A12_RS13495 4a935ced96aebf9fdfd5246bfa9e050a 163 Gene3D G3DSA:3.40.50.620 2 162 2.0E-33 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS13495 4a935ced96aebf9fdfd5246bfa9e050a 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 90 106 9.7E-48 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A6A12_RS13495 4a935ced96aebf9fdfd5246bfa9e050a 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 25 46 9.7E-48 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A6A12_RS13495 4a935ced96aebf9fdfd5246bfa9e050a 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 54 78 9.7E-48 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A6A12_RS13495 4a935ced96aebf9fdfd5246bfa9e050a 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 117 139 9.7E-48 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A6A12_RS13495 4a935ced96aebf9fdfd5246bfa9e050a 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 7 25 9.7E-48 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A6A12_RS13495 4a935ced96aebf9fdfd5246bfa9e050a 163 Pfam PF01467 Cytidylyltransferase-like 10 138 3.0E-19 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A6A12_RS13495 4a935ced96aebf9fdfd5246bfa9e050a 163 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 68 2.5E-19 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A6A12_RS13495 4a935ced96aebf9fdfd5246bfa9e050a 163 SUPERFAMILY SSF52374 8 162 1.66E-43 T 28-03-2018 A6A12_RS13495 4a935ced96aebf9fdfd5246bfa9e050a 163 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 7 163 34.203 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A6A12_RS13495 4a935ced96aebf9fdfd5246bfa9e050a 163 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 9 161 4.4E-58 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A6A12_RS12480 e66432f985a9955f8849b78c7d51e32f 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS12480 e66432f985a9955f8849b78c7d51e32f 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 5.3E-50 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12480 e66432f985a9955f8849b78c7d51e32f 110 SUPERFAMILY SSF54843 1 109 1.05E-44 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A6A12_RS12480 e66432f985a9955f8849b78c7d51e32f 110 Gene3D G3DSA:3.90.470.10 1 110 1.2E-45 T 28-03-2018 A6A12_RS12480 e66432f985a9955f8849b78c7d51e32f 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 29.606 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 A6A12_RS12480 e66432f985a9955f8849b78c7d51e32f 110 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 2.6E-39 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A6A12_RS08610 7083b7bda935503928c5f5b969376651 331 Hamap MF_00730 Nucleoid-associated protein YejK [yejK]. 3 330 40.015 T 28-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 A6A12_RS08610 7083b7bda935503928c5f5b969376651 331 Pfam PF04245 37-kD nucleoid-associated bacterial protein 10 324 1.4E-84 T 28-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 A6A12_RS06095 64f4f094be37215ac7f55dc5d73a34d5 219 Pfam PF11140 Protein of unknown function (DUF2913) 3 213 1.4E-84 T 28-03-2018 IPR021316 Protein of unknown function DUF2913 A6A12_RS05830 92adac74d75329699cc36d15bf22cccf 288 Gene3D G3DSA:3.20.20.410 2 268 4.3E-70 T 28-03-2018 IPR002763 Protein of unknown function DUF72 A6A12_RS05830 92adac74d75329699cc36d15bf22cccf 288 SUPERFAMILY SSF117396 3 265 2.09E-71 T 28-03-2018 IPR002763 Protein of unknown function DUF72 A6A12_RS05830 92adac74d75329699cc36d15bf22cccf 288 Pfam PF01904 Protein of unknown function DUF72 23 262 4.2E-55 T 28-03-2018 IPR002763 Protein of unknown function DUF72 A6A12_RS07820 be872d366fd62f93ee13594ea8da6a01 493 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 22 492 6.7E-175 T 28-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath A6A12_RS07820 be872d366fd62f93ee13594ea8da6a01 493 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 65 492 1.2E-163 T 28-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath A6A12_RS04430 e7722180ac7b593e9bd5adbc7d815058 169 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 85 97 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A6A12_RS04430 e7722180ac7b593e9bd5adbc7d815058 169 SUPERFAMILY SSF51261 18 166 3.66E-55 T 28-03-2018 IPR011055 Duplicated hybrid motif A6A12_RS04430 e7722180ac7b593e9bd5adbc7d815058 169 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 23 143 1.9E-50 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A6A12_RS04430 e7722180ac7b593e9bd5adbc7d815058 169 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 22 146 2.1E-49 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 A6A12_RS04430 e7722180ac7b593e9bd5adbc7d815058 169 Gene3D G3DSA:2.70.70.10 9 169 1.6E-57 T 28-03-2018 A6A12_RS05110 a0722db5118740144b538641e47d654b 593 Gene3D G3DSA:3.20.20.80 1 489 4.0E-67 T 28-03-2018 A6A12_RS05110 a0722db5118740144b538641e47d654b 593 SMART SM00642 10 457 1.3E-7 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A6A12_RS05110 a0722db5118740144b538641e47d654b 593 Pfam PF00128 Alpha amylase, catalytic domain 43 157 8.0E-12 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A6A12_RS05110 a0722db5118740144b538641e47d654b 593 Pfam PF00128 Alpha amylase, catalytic domain 269 427 1.8E-11 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A6A12_RS05110 a0722db5118740144b538641e47d654b 593 SUPERFAMILY SSF51445 3 487 9.11E-87 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A6A12_RS05110 a0722db5118740144b538641e47d654b 593 Gene3D G3DSA:2.60.40.1180 498 579 8.3E-7 T 28-03-2018 A6A12_RS07835 5c4ace3737a57112ec491e6af66e2ab2 463 Pfam PF06812 ImpA, N-terminal, type VI secretion system 13 158 4.3E-20 T 28-03-2018 IPR010657 ImpA, N-terminal A6A12_RS08335 2ea5c7308d7f947491d36e2e2839a99c 203 Gene3D G3DSA:2.60.120.200 10 165 7.4E-4 T 28-03-2018 A6A12_RS05580 ead605402a9c5e10a9a19f84b6c9aea6 165 SUPERFAMILY SSF52172 1 144 3.56E-20 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS05580 ead605402a9c5e10a9a19f84b6c9aea6 165 SMART SM00448 4 125 3.6E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS05580 ead605402a9c5e10a9a19f84b6c9aea6 165 Pfam PF00072 Response regulator receiver domain 6 125 2.3E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS05580 ead605402a9c5e10a9a19f84b6c9aea6 165 Gene3D G3DSA:3.40.50.2300 1 160 1.1E-16 T 28-03-2018 A6A12_RS06635 512e06eef19a7213a243a6ef55bebd6b 80 Pfam PF05768 Glutaredoxin-like domain (DUF836) 3 72 2.7E-19 T 28-03-2018 IPR008554 Glutaredoxin-like A6A12_RS06635 512e06eef19a7213a243a6ef55bebd6b 80 SUPERFAMILY SSF52833 2 73 1.57E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold A6A12_RS06635 512e06eef19a7213a243a6ef55bebd6b 80 Gene3D G3DSA:3.40.30.10 2 73 5.4E-10 T 28-03-2018 A6A12_RS02425 5c6e6156cb1688c56e40ba22286b0db9 296 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 295 1.2E-123 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A6A12_RS02425 5c6e6156cb1688c56e40ba22286b0db9 296 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 284 7.7E-63 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A6A12_RS02425 5c6e6156cb1688c56e40ba22286b0db9 296 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A6A12_RS02425 5c6e6156cb1688c56e40ba22286b0db9 296 Gene3D G3DSA:3.40.50.1100 137 296 1.2E-41 T 28-03-2018 A6A12_RS02425 5c6e6156cb1688c56e40ba22286b0db9 296 TIGRFAM TIGR01138 cysM: cysteine synthase B 6 295 2.2E-150 T 28-03-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 A6A12_RS02425 5c6e6156cb1688c56e40ba22286b0db9 296 SUPERFAMILY SSF53686 4 293 6.55E-88 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme A6A12_RS02425 5c6e6156cb1688c56e40ba22286b0db9 296 Gene3D G3DSA:3.40.50.1100 41 136 5.0E-34 T 28-03-2018 A6A12_RS14065 b574aa5136d3b7653db30b35e090b158 258 Gene3D G3DSA:3.20.20.140 1 257 3.3E-69 T 28-03-2018 A6A12_RS14065 b574aa5136d3b7653db30b35e090b158 258 Pfam PF01026 TatD related DNase 2 252 3.9E-63 T 28-03-2018 IPR001130 TatD family GO:0016788 A6A12_RS14065 b574aa5136d3b7653db30b35e090b158 258 PIRSF PIRSF005902 1 256 4.8E-69 T 28-03-2018 IPR001130 TatD family GO:0016788 A6A12_RS14065 b574aa5136d3b7653db30b35e090b158 258 SUPERFAMILY SSF51556 1 253 2.84E-77 T 28-03-2018 IPR032466 Metal-dependent hydrolase A6A12_RS14065 b574aa5136d3b7653db30b35e090b158 258 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 252 4.9E-70 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A6A12_RS09295 96afc0e778488842b1294df3ea533d3b 514 Gene3D G3DSA:1.10.275.10 1 203 1.2E-62 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal A6A12_RS09295 96afc0e778488842b1294df3ea533d3b 514 SUPERFAMILY SSF48557 3 512 5.34E-171 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 A6A12_RS09295 96afc0e778488842b1294df3ea533d3b 514 Gene3D G3DSA:1.20.200.10 204 513 5.6E-98 T 28-03-2018 A6A12_RS09295 96afc0e778488842b1294df3ea533d3b 514 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 145 161 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 A6A12_RS09295 96afc0e778488842b1294df3ea533d3b 514 Pfam PF00221 Aromatic amino acid lyase 16 465 8.6E-163 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 A6A12_RS10460 b885227f6471d8a82b2f3e27979d7fe4 485 Gene3D G3DSA:1.25.40.10 368 474 1.3E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS10460 b885227f6471d8a82b2f3e27979d7fe4 485 Hamap MF_00997 Beta-barrel assembly-enhancing protease [bepA]. 2 484 40.369 T 28-03-2018 IPR030873 Beta-barrel assembly-enhancing protease GO:0006508|GO:0008237|GO:0016020|GO:0061077 A6A12_RS10460 b885227f6471d8a82b2f3e27979d7fe4 485 Pfam PF14559 Tetratricopeptide repeat 353 416 3.5E-10 T 28-03-2018 A6A12_RS10460 b885227f6471d8a82b2f3e27979d7fe4 485 Gene3D G3DSA:1.25.40.10 237 367 1.4E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS10460 b885227f6471d8a82b2f3e27979d7fe4 485 Pfam PF01435 Peptidase family M48 71 256 2.5E-27 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A6A12_RS10460 b885227f6471d8a82b2f3e27979d7fe4 485 SUPERFAMILY SSF48452 291 467 1.04E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS10460 b885227f6471d8a82b2f3e27979d7fe4 485 Gene3D G3DSA:3.30.2010.10 57 152 1.7E-15 T 28-03-2018 A6A12_RS12360 90b94509ebeec6d615062f26e33b7327 150 Pfam PF13673 Acetyltransferase (GNAT) domain 42 149 2.1E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 A6A12_RS12360 90b94509ebeec6d615062f26e33b7327 150 SUPERFAMILY SSF55729 1 149 3.37E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS12360 90b94509ebeec6d615062f26e33b7327 150 Gene3D G3DSA:3.40.630.30 1 149 3.4E-30 T 28-03-2018 A6A12_RS09635 cc31f61acda04c287d09cf09baa0a43e 486 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 428 448 5.3E-36 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS09635 cc31f61acda04c287d09cf09baa0a43e 486 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 388 408 5.3E-36 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS09635 cc31f61acda04c287d09cf09baa0a43e 486 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 40 59 5.3E-36 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS09635 cc31f61acda04c287d09cf09baa0a43e 486 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 84 110 5.3E-36 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS09635 cc31f61acda04c287d09cf09baa0a43e 486 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 257 277 5.3E-36 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS09635 cc31f61acda04c287d09cf09baa0a43e 486 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 311 330 5.3E-36 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS09635 cc31f61acda04c287d09cf09baa0a43e 486 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 11 32 5.3E-36 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS09635 cc31f61acda04c287d09cf09baa0a43e 486 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 27 41 - T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS09635 cc31f61acda04c287d09cf09baa0a43e 486 SUPERFAMILY SSF161070 3 470 3.53E-146 T 28-03-2018 A6A12_RS09635 cc31f61acda04c287d09cf09baa0a43e 486 Pfam PF00209 Sodium:neurotransmitter symporter family 123 474 6.6E-78 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A6A12_RS12700 1a5106699f63843de79ee13fdd37e97f 200 Pfam PF05137 Fimbrial assembly protein (PilN) 102 177 2.0E-13 T 28-03-2018 IPR007813 Fimbrial assembly PilN A6A12_RS06575 531b6ac1aebc48bb01e90feac4e0a463 419 Pfam PF04403 Paraquat-inducible protein A 59 208 3.9E-36 T 28-03-2018 IPR007498 Paraquat-inducible protein A A6A12_RS06575 531b6ac1aebc48bb01e90feac4e0a463 419 Pfam PF04403 Paraquat-inducible protein A 251 407 2.7E-47 T 28-03-2018 IPR007498 Paraquat-inducible protein A A6A12_RS06575 531b6ac1aebc48bb01e90feac4e0a463 419 TIGRFAM TIGR00155 pqiA_fam: integral membrane protein, PqiA family 15 405 2.3E-107 T 28-03-2018 IPR005219 Conserved hypothetical protein CHP00155 A6A12_RS04500 7aef67802a863b8783d59660311e3919 304 Gene3D G3DSA:3.40.50.720 1 304 1.2E-34 T 28-03-2018 A6A12_RS04500 7aef67802a863b8783d59660311e3919 304 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 296 2.7E-100 T 28-03-2018 IPR010099 Epimerase family protein SDR39U1 A6A12_RS04500 7aef67802a863b8783d59660311e3919 304 SUPERFAMILY SSF51735 1 301 1.15E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS04500 7aef67802a863b8783d59660311e3919 304 Pfam PF08338 Domain of unknown function (DUF1731) 253 299 1.6E-16 T 28-03-2018 IPR013549 Domain of unknown function DUF1731 A6A12_RS04500 7aef67802a863b8783d59660311e3919 304 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 225 1.4E-19 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A6A12_RS07865 bfb013636f0d948164f5a50b8bebf3ff 403 Pfam PF00589 Phage integrase family 213 378 8.4E-19 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS07865 bfb013636f0d948164f5a50b8bebf3ff 403 Pfam PF12167 Arm DNA-binding domain 1 64 8.2E-21 T 28-03-2018 IPR022000 Min27-like integrase, DNA-binding domain A6A12_RS07865 bfb013636f0d948164f5a50b8bebf3ff 403 Gene3D G3DSA:1.10.150.130 100 189 1.2E-11 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A6A12_RS07865 bfb013636f0d948164f5a50b8bebf3ff 403 SUPERFAMILY SSF56349 101 385 1.41E-51 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS07865 bfb013636f0d948164f5a50b8bebf3ff 403 Gene3D G3DSA:1.10.443.10 210 386 6.4E-32 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS07865 bfb013636f0d948164f5a50b8bebf3ff 403 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 102 158 8.2E-5 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A6A12_RS11715 8fb6f54c56160baebe0654549ac5a0eb 507 Pfam PF01928 CYTH domain 3 197 2.3E-36 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A6A12_RS11715 8fb6f54c56160baebe0654549ac5a0eb 507 Pfam PF05235 CHAD domain 230 396 4.9E-8 T 28-03-2018 IPR007899 CHAD domain A6A12_RS11715 8fb6f54c56160baebe0654549ac5a0eb 507 SMART SM00880 229 497 5.8E-23 T 28-03-2018 IPR007899 CHAD domain A6A12_RS11715 8fb6f54c56160baebe0654549ac5a0eb 507 SMART SM01118 2 203 1.5E-42 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A6A12_RS11715 8fb6f54c56160baebe0654549ac5a0eb 507 Gene3D G3DSA:2.40.320.10 1 209 2.4E-42 T 28-03-2018 A6A12_RS11715 8fb6f54c56160baebe0654549ac5a0eb 507 SUPERFAMILY SSF55154 1 214 2.45E-51 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 A6A12_RS05765 6cdadf57a8a67fc9cb7049fa25c44710 215 SUPERFAMILY SSF89155 8 213 1.27E-49 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone A6A12_RS05765 6cdadf57a8a67fc9cb7049fa25c44710 215 Hamap MF_01150 Chaperone protein TorD [torD]. 3 212 33.385 T 28-03-2018 IPR023069 Chaperone TorD A6A12_RS05765 6cdadf57a8a67fc9cb7049fa25c44710 215 Gene3D G3DSA:1.10.3480.10 1 215 5.0E-45 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone A6A12_RS05765 6cdadf57a8a67fc9cb7049fa25c44710 215 Pfam PF02613 Nitrate reductase delta subunit 52 181 1.0E-37 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone A6A12_RS02370 a61b209a62e39fe9f9f3084ecf31f4be 163 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 129 7.6E-29 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A6A12_RS02370 a61b209a62e39fe9f9f3084ecf31f4be 163 SUPERFAMILY SSF55083 1 146 2.49E-36 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A6A12_RS02370 a61b209a62e39fe9f9f3084ecf31f4be 163 Gene3D G3DSA:3.30.70.560 1 157 7.3E-37 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A6A12_RS02370 a61b209a62e39fe9f9f3084ecf31f4be 163 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 129 4.8E-25 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A6A12_RS10380 11156c9fcbc37c3f2dfb2bc564f1ccf2 329 Pfam PF09952 Transcriptional regulator, AbiEi antitoxin, Type IV TA system 193 321 6.2E-10 T 28-03-2018 IPR019238 Transcriptional regulator, AbiEi 2 antitoxin, Type IV TA system A6A12_RS11140 276c631abb42b28e25399bd0ebb5057b 143 SUPERFAMILY SSF82649 3 139 4.92E-47 T 28-03-2018 A6A12_RS11140 276c631abb42b28e25399bd0ebb5057b 143 Gene3D G3DSA:3.90.1010.10 2 140 7.9E-46 T 28-03-2018 A6A12_RS11140 276c631abb42b28e25399bd0ebb5057b 143 Pfam PF02657 Fe-S metabolism associated domain 21 139 1.6E-43 T 28-03-2018 IPR003808 Fe-S metabolism associated domain, SufE-like A6A12_RS11140 276c631abb42b28e25399bd0ebb5057b 143 TIGRFAM TIGR03391 FeS_syn_CsdE: cysteine desulfurase, sulfur acceptor subunit CsdE 7 140 2.1E-44 T 28-03-2018 IPR017763 Cysteine desulfurase, sulphur acceptor subunit CsdE A6A12_RS07555 bafa490d61f0f33140a2742ea000b426 136 Pfam PF02472 Biopolymer transport protein ExbD/TolR 15 133 5.4E-20 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 A6A12_RS13805 f6d6cc56b3ffd41d30434e507cdbbc39 562 Gene3D G3DSA:1.10.150.130 47 182 3.0E-6 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A6A12_RS10705 22e595f6cddf44cad55cdc3c3f04cd58 339 Gene3D G3DSA:3.30.1330.60 213 339 1.8E-40 T 28-03-2018 IPR006665 OmpA-like domain A6A12_RS10705 22e595f6cddf44cad55cdc3c3f04cd58 339 PRINTS PR01021 OMPA domain signature 231 253 1.2E-12 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A6A12_RS10705 22e595f6cddf44cad55cdc3c3f04cd58 339 PRINTS PR01021 OMPA domain signature 261 276 1.2E-12 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A6A12_RS10705 22e595f6cddf44cad55cdc3c3f04cd58 339 PRINTS PR01021 OMPA domain signature 276 292 1.2E-12 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 A6A12_RS10705 22e595f6cddf44cad55cdc3c3f04cd58 339 Pfam PF01389 OmpA-like transmembrane domain 31 183 1.7E-38 T 28-03-2018 IPR000498 Outer membrane protein OmpA-like, transmembrane domain GO:0009279|GO:0016021 A6A12_RS10705 22e595f6cddf44cad55cdc3c3f04cd58 339 Pfam PF00691 OmpA family 231 325 6.0E-23 T 28-03-2018 IPR006665 OmpA-like domain A6A12_RS10705 22e595f6cddf44cad55cdc3c3f04cd58 339 Gene3D G3DSA:2.40.160.20 15 212 1.1E-29 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A6A12_RS10705 22e595f6cddf44cad55cdc3c3f04cd58 339 SUPERFAMILY SSF56925 30 184 2.88E-26 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A6A12_RS10705 22e595f6cddf44cad55cdc3c3f04cd58 339 SUPERFAMILY SSF103088 208 331 1.7E-36 T 28-03-2018 IPR006665 OmpA-like domain A6A12_RS12350 e12b3961bc36b74b8ff54bd2beff11a5 589 Gene3D G3DSA:3.40.1130.10 32 265 2.0E-26 T 28-03-2018 A6A12_RS12350 e12b3961bc36b74b8ff54bd2beff11a5 589 Pfam PF01553 Acyltransferase 65 194 2.2E-5 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A6A12_RS12350 e12b3961bc36b74b8ff54bd2beff11a5 589 SUPERFAMILY SSF69593 43 252 2.09E-12 T 28-03-2018 A6A12_RS12350 e12b3961bc36b74b8ff54bd2beff11a5 589 SUPERFAMILY SSF55729 312 459 4.56E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS12350 e12b3961bc36b74b8ff54bd2beff11a5 589 Pfam PF13444 Acetyltransferase (GNAT) domain 330 430 8.6E-19 T 28-03-2018 A6A12_RS12350 e12b3961bc36b74b8ff54bd2beff11a5 589 SMART SM00563 74 197 1.2E-9 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 A6A12_RS12350 e12b3961bc36b74b8ff54bd2beff11a5 589 Gene3D G3DSA:3.40.630.30 310 467 6.4E-21 T 28-03-2018 A6A12_RS10500 83f949a849f43cf04f0ba4e99a468ff1 283 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 13 277 48.113 T 28-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A6A12_RS10500 83f949a849f43cf04f0ba4e99a468ff1 283 Pfam PF00793 DAHP synthetase I family 10 275 2.6E-68 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A6A12_RS10500 83f949a849f43cf04f0ba4e99a468ff1 283 SUPERFAMILY SSF51569 2 279 5.5E-104 T 28-03-2018 A6A12_RS10500 83f949a849f43cf04f0ba4e99a468ff1 283 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 18 275 7.4E-116 T 28-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 A6A12_RS10500 83f949a849f43cf04f0ba4e99a468ff1 283 Gene3D G3DSA:3.20.20.70 16 280 3.1E-67 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A6A12_RS04475 6a16c8a2622b7b99dbe7990a790e1e83 415 Pfam PF14319 Transposase zinc-binding domain 30 135 5.7E-28 T 28-03-2018 IPR026889 Transposase zinc-binding domain A6A12_RS04475 6a16c8a2622b7b99dbe7990a790e1e83 415 Pfam PF04986 Putative transposase 158 336 2.7E-51 T 28-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 A6A12_RS10090 13bcc1454daad9a93399da8fc0bb9c48 172 SUPERFAMILY SSF54637 11 156 3.06E-23 T 28-03-2018 IPR029069 HotDog domain A6A12_RS10090 13bcc1454daad9a93399da8fc0bb9c48 172 Gene3D G3DSA:3.10.129.10 9 169 5.9E-21 T 28-03-2018 A6A12_RS10090 13bcc1454daad9a93399da8fc0bb9c48 172 Pfam PF14539 Domain of unknown function (DUF4442) 14 151 6.1E-26 T 28-03-2018 IPR027961 Protein of unknown function DUF4442 A6A12_RS09435 4c02359a2372324c072f866cab964791 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.1E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09435 4c02359a2372324c072f866cab964791 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.1E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09435 4c02359a2372324c072f866cab964791 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.1E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09435 4c02359a2372324c072f866cab964791 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.1E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09435 4c02359a2372324c072f866cab964791 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.1E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09435 4c02359a2372324c072f866cab964791 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A6A12_RS09435 4c02359a2372324c072f866cab964791 265 SUPERFAMILY SSF51735 1 259 2.26E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS09435 4c02359a2372324c072f866cab964791 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09435 4c02359a2372324c072f866cab964791 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09435 4c02359a2372324c072f866cab964791 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09435 4c02359a2372324c072f866cab964791 265 Pfam PF00106 short chain dehydrogenase 6 196 9.6E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09435 4c02359a2372324c072f866cab964791 265 Gene3D G3DSA:3.40.50.720 1 263 9.8E-49 T 28-03-2018 A6A12_RS04315 43821aaa28be524f2cbafa4a59b77483 464 Pfam PF02397 Bacterial sugar transferase 274 456 4.4E-65 T 28-03-2018 IPR003362 Bacterial sugar transferase A6A12_RS04315 43821aaa28be524f2cbafa4a59b77483 464 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 22 464 2.7E-172 T 28-03-2018 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 A6A12_RS04315 43821aaa28be524f2cbafa4a59b77483 464 Gene3D G3DSA:3.40.50.720 140 263 7.7E-17 T 28-03-2018 A6A12_RS04315 43821aaa28be524f2cbafa4a59b77483 464 Pfam PF13727 CoA-binding domain 62 238 3.9E-44 T 28-03-2018 A6A12_RS04315 43821aaa28be524f2cbafa4a59b77483 464 SUPERFAMILY SSF51735 142 269 8.27E-11 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS04315 43821aaa28be524f2cbafa4a59b77483 464 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 21 464 2.6E-151 T 28-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase A6A12_RS02455 221a51e0851bf7283eb2f94273ef12ff 348 Pfam PF00154 recA bacterial DNA recombination protein 7 267 2.6E-142 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A6A12_RS02455 221a51e0851bf7283eb2f94273ef12ff 348 Gene3D G3DSA:3.30.250.10 269 326 2.8E-23 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal A6A12_RS02455 221a51e0851bf7283eb2f94273ef12ff 348 Gene3D G3DSA:3.40.50.300 26 268 3.4E-45 T 28-03-2018 A6A12_RS02455 221a51e0851bf7283eb2f94273ef12ff 348 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 324 2.4E-168 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A6A12_RS02455 221a51e0851bf7283eb2f94273ef12ff 348 PRINTS PR00142 RecA protein signature 93 122 1.4E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A6A12_RS02455 221a51e0851bf7283eb2f94273ef12ff 348 PRINTS PR00142 RecA protein signature 210 238 1.4E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A6A12_RS02455 221a51e0851bf7283eb2f94273ef12ff 348 PRINTS PR00142 RecA protein signature 127 156 1.4E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A6A12_RS02455 221a51e0851bf7283eb2f94273ef12ff 348 PRINTS PR00142 RecA protein signature 297 314 1.4E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A6A12_RS02455 221a51e0851bf7283eb2f94273ef12ff 348 PRINTS PR00142 RecA protein signature 243 272 1.4E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A6A12_RS02455 221a51e0851bf7283eb2f94273ef12ff 348 PRINTS PR00142 RecA protein signature 165 194 1.4E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A6A12_RS02455 221a51e0851bf7283eb2f94273ef12ff 348 SMART SM00382 57 228 2.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS02455 221a51e0851bf7283eb2f94273ef12ff 348 SUPERFAMILY SSF54752 269 325 1.16E-19 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal A6A12_RS02455 221a51e0851bf7283eb2f94273ef12ff 348 ProSitePatterns PS00321 recA signature. 213 221 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 A6A12_RS02455 221a51e0851bf7283eb2f94273ef12ff 348 Hamap MF_00268 Protein RecA [recA]. 5 329 50.198 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 A6A12_RS02455 221a51e0851bf7283eb2f94273ef12ff 348 SUPERFAMILY SSF52540 4 266 3.36E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS09095 fb196b520b0b51436dcd143587146115 386 Gene3D G3DSA:1.10.10.680 166 239 9.0E-35 T 28-03-2018 A6A12_RS09095 fb196b520b0b51436dcd143587146115 386 SUPERFAMILY SSF52980 1 382 9.83E-117 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A6A12_RS09095 fb196b520b0b51436dcd143587146115 386 Gene3D G3DSA:3.40.1350.10 240 383 5.3E-38 T 28-03-2018 A6A12_RS09095 fb196b520b0b51436dcd143587146115 386 Pfam PF09002 Domain of unknown function (DUF1887) 1 379 7.6E-165 T 28-03-2018 IPR015093 Protein of unknown function DUF1887 A6A12_RS09095 fb196b520b0b51436dcd143587146115 386 Gene3D G3DSA:3.40.50.10770 1 140 8.8E-22 T 28-03-2018 A6A12_RS00650 16198b557d475dc0d93588fc003c14bc 729 SUPERFAMILY SSF56349 496 544 6.18E-6 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS00650 16198b557d475dc0d93588fc003c14bc 729 SUPERFAMILY SSF56349 339 366 6.18E-6 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS00650 16198b557d475dc0d93588fc003c14bc 729 SUPERFAMILY SSF56349 402 469 6.18E-6 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS00650 16198b557d475dc0d93588fc003c14bc 729 Gene3D G3DSA:1.10.443.10 330 549 5.3E-9 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS06855 c4ff2b2745e9b2388627c37018cb9382 243 SMART SM01144 27 221 1.1E-64 T 28-03-2018 IPR005636 DTW A6A12_RS06855 c4ff2b2745e9b2388627c37018cb9382 243 Pfam PF03942 DTW domain 29 215 8.8E-42 T 28-03-2018 IPR005636 DTW A6A12_RS09440 24678dadb541bc625e66365206dd8f80 244 SUPERFAMILY SSF48613 3 219 4.45E-58 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A6A12_RS09440 24678dadb541bc625e66365206dd8f80 244 SMART SM01236 74 175 1.6E-7 T 28-03-2018 A6A12_RS09440 24678dadb541bc625e66365206dd8f80 244 Pfam PF14518 Iron-containing redox enzyme 40 211 9.0E-26 T 28-03-2018 IPR028201 PqqC-like protein A6A12_RS09440 24678dadb541bc625e66365206dd8f80 244 Gene3D G3DSA:1.20.910.10 1 235 1.6E-37 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 A6A12_RS09730 ae1ba78e372c3e1417f93eb1d22d1163 291 SUPERFAMILY SSF103481 197 291 5.36E-6 T 28-03-2018 A6A12_RS09730 ae1ba78e372c3e1417f93eb1d22d1163 291 SUPERFAMILY SSF103481 48 143 2.62E-6 T 28-03-2018 A6A12_RS03285 4f576bb848d004f3cfcd5fc88e15c3b4 175 TIGRFAM TIGR00258 TIGR00258: inosine/xanthosine triphosphatase 6 170 1.0E-44 T 28-03-2018 IPR002786 Non-canonical purine NTP phosphatase A6A12_RS03285 4f576bb848d004f3cfcd5fc88e15c3b4 175 Pfam PF01931 Protein of unknown function DUF84 7 166 5.1E-59 T 28-03-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 A6A12_RS03285 4f576bb848d004f3cfcd5fc88e15c3b4 175 Hamap MF_00648 Non-canonical purine NTP phosphatase. 2 171 29.694 T 28-03-2018 IPR002786 Non-canonical purine NTP phosphatase A6A12_RS03285 4f576bb848d004f3cfcd5fc88e15c3b4 175 SUPERFAMILY SSF52972 2 171 2.4E-59 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A6A12_RS03285 4f576bb848d004f3cfcd5fc88e15c3b4 175 Gene3D G3DSA:3.90.950.10 1 170 5.7E-63 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A6A12_RS09815 f73acce619b33b73827684ee3bc5fea5 188 Pfam PF11993 Ribosomal S4P (gammaproteobacterial) 22 184 7.5E-64 T 28-03-2018 IPR021879 Ribosomal S4P (gammaproteobacterial) A6A12_RS06870 901de441b2697d91b602208bc5cd78bc 170 Gene3D G3DSA:3.90.1720.10 42 169 2.9E-35 T 28-03-2018 A6A12_RS06870 901de441b2697d91b602208bc5cd78bc 170 Pfam PF00877 NlpC/P60 family 58 162 4.4E-31 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain A6A12_RS06870 901de441b2697d91b602208bc5cd78bc 170 SUPERFAMILY SSF54001 46 165 1.23E-39 T 28-03-2018 A6A12_RS08260 9e4c48ad7047189646b4ab7a276de169 227 Pfam PF10979 Protein of unknown function (DUF2786) 5 42 9.5E-12 T 28-03-2018 IPR024498 Domain of unknown function DUF2786 A6A12_RS08260 9e4c48ad7047189646b4ab7a276de169 227 PIRSF PIRSF028111 1 226 1.2E-83 T 28-03-2018 IPR016868 Bacteriophage B3, Orf5 A6A12_RS08260 9e4c48ad7047189646b4ab7a276de169 227 Gene3D G3DSA:3.30.565.40 155 217 6.6E-4 T 28-03-2018 A6A12_RS03875 68192b8ff3875fdbed48f71bb6801ea5 119 Gene3D G3DSA:3.30.1450.10 35 105 2.4E-11 T 28-03-2018 A6A12_RS03875 68192b8ff3875fdbed48f71bb6801ea5 119 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 7 112 32.169 T 28-03-2018 IPR026592 Outer membrane protein assembly factor BamE A6A12_RS03875 68192b8ff3875fdbed48f71bb6801ea5 119 Pfam PF04355 SmpA / OmlA family 35 102 2.2E-23 T 28-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 A6A12_RS12115 8563296a567230c30767589a6461c7e1 163 Pfam PF02470 MlaD protein 40 118 7.3E-19 T 28-03-2018 IPR003399 Mce/MlaD A6A12_RS12115 8563296a567230c30767589a6461c7e1 163 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 4 152 7.4E-56 T 28-03-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 A6A12_RS05370 a8e68f8c6b828b6403ac0744e52f75ae 98 Gene3D G3DSA:3.30.70.1060 1 98 2.5E-27 T 28-03-2018 A6A12_RS05370 a8e68f8c6b828b6403ac0744e52f75ae 98 Pfam PF03795 YCII-related domain 1 95 3.3E-29 T 28-03-2018 IPR005545 YCII-related A6A12_RS05370 a8e68f8c6b828b6403ac0744e52f75ae 98 SUPERFAMILY SSF54909 1 98 5.54E-32 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel A6A12_RS00450 2ab28c0dec2d7e4c92eb600ed6ce3b5c 337 Pfam PF01757 Acyltransferase family 7 327 1.3E-34 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 A6A12_RS00835 c34e8914aaaf1f388f0b3c76ba7af65d 644 Pfam PF05170 AsmA family 1 543 3.4E-103 T 28-03-2018 IPR007844 AsmA A6A12_RS03120 e3f0756a4951bf7a03f50367a462e995 143 SUPERFAMILY SSF55831 2 112 3.27E-32 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A6A12_RS03120 e3f0756a4951bf7a03f50367a462e995 143 Gene3D G3DSA:3.30.572.10 1 112 3.0E-27 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A6A12_RS03120 e3f0756a4951bf7a03f50367a462e995 143 Pfam PF00303 Thymidylate synthase 2 111 4.5E-23 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 A6A12_RS13160 2bafc44f29e4e8e36c84657e718dd1db 195 Gene3D G3DSA:1.20.1590.10 5 195 1.2E-74 T 28-03-2018 IPR023381 YP001051499.1-like domain A6A12_RS13160 2bafc44f29e4e8e36c84657e718dd1db 195 Pfam PF04222 Protein of unknown function (DUF416) 6 194 4.1E-79 T 28-03-2018 IPR007338 Protein of unknown function DUF416 A6A12_RS07780 068bb2fb4e3a0875e3c1e59d21230afa 377 Pfam PF04392 ABC transporter substrate binding protein 97 357 2.3E-13 T 28-03-2018 IPR007487 ABC transporter, substrate-binding protein A6A12_RS07780 068bb2fb4e3a0875e3c1e59d21230afa 377 Gene3D G3DSA:3.40.50.2300 2 243 4.9E-4 T 28-03-2018 A6A12_RS10210 465fcc75cd41ef89258494fae45cb8db 267 Pfam PF02108 Flagellar assembly protein FliH 125 251 1.1E-32 T 28-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE A6A12_RS10210 465fcc75cd41ef89258494fae45cb8db 267 PRINTS PR01003 Flagellar assembly protein FliH signature 85 107 7.1E-7 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 A6A12_RS10210 465fcc75cd41ef89258494fae45cb8db 267 PRINTS PR01003 Flagellar assembly protein FliH signature 217 233 7.1E-7 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 A6A12_RS10210 465fcc75cd41ef89258494fae45cb8db 267 PRINTS PR01003 Flagellar assembly protein FliH signature 147 164 7.1E-7 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 A6A12_RS10210 465fcc75cd41ef89258494fae45cb8db 267 PRINTS PR01003 Flagellar assembly protein FliH signature 108 126 7.1E-7 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 A6A12_RS06055 0642a7e51f12aef3e204604127651902 130 Pfam PF12614 Ribosome recycling factor 5 128 4.1E-55 T 28-03-2018 IPR022253 Ribosome recycling factor. bacterial A6A12_RS01805 8b0f6d346def1a3ca9e63f1df2cf495b 330 Gene3D G3DSA:3.40.718.10 1 330 6.8E-126 T 28-03-2018 A6A12_RS01805 8b0f6d346def1a3ca9e63f1df2cf495b 330 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 2 325 35.607 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 A6A12_RS01805 8b0f6d346def1a3ca9e63f1df2cf495b 330 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 32 321 7.1E-105 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 A6A12_RS01805 8b0f6d346def1a3ca9e63f1df2cf495b 330 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 5 324 1.3E-125 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 A6A12_RS01805 8b0f6d346def1a3ca9e63f1df2cf495b 330 SUPERFAMILY SSF53659 4 326 1.47E-111 T 28-03-2018 A6A12_RS00210 1a60663f4fb305eb0c46681547578523 328 Gene3D G3DSA:3.90.1200.10 112 324 2.9E-22 T 28-03-2018 A6A12_RS00210 1a60663f4fb305eb0c46681547578523 328 Hamap MF_01497 Stress response kinase A [srkA]. 4 318 46.375 T 28-03-2018 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 A6A12_RS00210 1a60663f4fb305eb0c46681547578523 328 Gene3D G3DSA:3.30.200.20 5 107 3.1E-18 T 28-03-2018 A6A12_RS00210 1a60663f4fb305eb0c46681547578523 328 SUPERFAMILY SSF56112 6 328 5.98E-89 T 28-03-2018 IPR011009 Protein kinase-like domain A6A12_RS00210 1a60663f4fb305eb0c46681547578523 328 Pfam PF01636 Phosphotransferase enzyme family 36 264 6.0E-42 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase A6A12_RS09620 5860cac30d3af247b3975812e2b759f2 399 SUPERFAMILY SSF52151 25 270 3.92E-32 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 A6A12_RS09620 5860cac30d3af247b3975812e2b759f2 399 Pfam PF01734 Patatin-like phospholipase 29 198 2.9E-18 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 A6A12_RS09620 5860cac30d3af247b3975812e2b759f2 399 Gene3D G3DSA:3.40.1090.10 18 314 1.6E-25 T 28-03-2018 A6A12_RS10615 fd42645e40e0db98b9fe4aa95f7809dc 363 PRINTS PR01010 Flagellar P-ring protein signature 37 52 1.4E-84 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 A6A12_RS10615 fd42645e40e0db98b9fe4aa95f7809dc 363 PRINTS PR01010 Flagellar P-ring protein signature 186 204 1.4E-84 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 A6A12_RS10615 fd42645e40e0db98b9fe4aa95f7809dc 363 PRINTS PR01010 Flagellar P-ring protein signature 102 119 1.4E-84 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 A6A12_RS10615 fd42645e40e0db98b9fe4aa95f7809dc 363 PRINTS PR01010 Flagellar P-ring protein signature 119 137 1.4E-84 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 A6A12_RS10615 fd42645e40e0db98b9fe4aa95f7809dc 363 PRINTS PR01010 Flagellar P-ring protein signature 80 99 1.4E-84 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 A6A12_RS10615 fd42645e40e0db98b9fe4aa95f7809dc 363 PRINTS PR01010 Flagellar P-ring protein signature 22 37 1.4E-84 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 A6A12_RS10615 fd42645e40e0db98b9fe4aa95f7809dc 363 PRINTS PR01010 Flagellar P-ring protein signature 160 178 1.4E-84 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 A6A12_RS10615 fd42645e40e0db98b9fe4aa95f7809dc 363 PRINTS PR01010 Flagellar P-ring protein signature 54 69 1.4E-84 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 A6A12_RS10615 fd42645e40e0db98b9fe4aa95f7809dc 363 PRINTS PR01010 Flagellar P-ring protein signature 250 262 1.4E-84 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 A6A12_RS10615 fd42645e40e0db98b9fe4aa95f7809dc 363 Pfam PF02119 Flagellar P-ring protein 22 362 8.4E-135 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 A6A12_RS10615 fd42645e40e0db98b9fe4aa95f7809dc 363 Hamap MF_00416 Flagellar P-ring protein [flgI]. 2 363 39.463 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 A6A12_RS13885 0528acbb3aa5bf35999449751eb455c2 513 Pfam PF13007 Transposase C of IS166 homeodomain 42 111 2.7E-13 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain A6A12_RS13885 0528acbb3aa5bf35999449751eb455c2 513 Pfam PF03050 Transposase IS66 family 183 466 3.2E-101 T 28-03-2018 IPR004291 Transposase, IS66 A6A12_RS13885 0528acbb3aa5bf35999449751eb455c2 513 Pfam PF13817 IS66 C-terminal element 473 509 3.3E-9 T 28-03-2018 A6A12_RS13885 0528acbb3aa5bf35999449751eb455c2 513 Pfam PF13005 zinc-finger binding domain of transposase IS66 119 163 1.7E-16 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 A6A12_RS09240 41311a2ec718dcc5f21cbcc22f437c1b 368 SUPERFAMILY SSF53335 111 353 2.36E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS09240 41311a2ec718dcc5f21cbcc22f437c1b 368 Gene3D G3DSA:3.40.50.150 110 359 1.2E-25 T 28-03-2018 A6A12_RS09240 41311a2ec718dcc5f21cbcc22f437c1b 368 PIRSF PIRSF005739 12 364 1.5E-7 T 28-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 A6A12_RS09240 41311a2ec718dcc5f21cbcc22f437c1b 368 Gene3D G3DSA:1.10.10.10 20 109 4.7E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS09240 41311a2ec718dcc5f21cbcc22f437c1b 368 Pfam PF00891 O-methyltransferase 191 350 2.0E-11 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 A6A12_RS09240 41311a2ec718dcc5f21cbcc22f437c1b 368 SUPERFAMILY SSF46785 31 111 2.54E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS07025 cee2f941a26df0526a4f78c574a37993 306 Pfam PF08878 Domain of unknown function (DUF1837) 52 291 1.6E-50 T 28-03-2018 IPR014976 Protein of unknown function DUF1837 A6A12_RS03935 46ccc511935d642cd087ccfc61fa435d 519 Pfam PF03806 AbgT putative transporter family 19 517 4.0E-211 T 28-03-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 A6A12_RS11255 dab117f4d12f8414b5584a044006e278 382 TIGRFAM TIGR00937 2A51: chromate efflux transporter 10 376 2.4E-94 T 28-03-2018 IPR014047 Chromate transporter, long chain A6A12_RS11255 dab117f4d12f8414b5584a044006e278 382 Pfam PF02417 Chromate transporter 5 170 1.8E-32 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A6A12_RS11255 dab117f4d12f8414b5584a044006e278 382 Pfam PF02417 Chromate transporter 213 376 6.6E-34 T 28-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 A6A12_RS11255 dab117f4d12f8414b5584a044006e278 382 PIRSF PIRSF004810 1 382 2.2E-115 T 28-03-2018 IPR014047 Chromate transporter, long chain A6A12_RS09385 29e46ba177004bcf960013d051728841 188 Gene3D G3DSA:3.10.450.50 22 188 8.2E-10 T 28-03-2018 A6A12_RS09385 29e46ba177004bcf960013d051728841 188 PIRSF PIRSF028288 1 188 2.8E-89 T 28-03-2018 IPR016878 Uncharacterised conserved protein UCP028288 A6A12_RS03600 992c9a9af6d37d68be39cf8929815bf7 285 SUPERFAMILY SSF53613 16 278 5.3E-79 T 28-03-2018 IPR029056 Ribokinase-like A6A12_RS03600 992c9a9af6d37d68be39cf8929815bf7 285 Gene3D G3DSA:3.40.1190.20 1 284 7.4E-57 T 28-03-2018 IPR029056 Ribokinase-like A6A12_RS03600 992c9a9af6d37d68be39cf8929815bf7 285 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 20 277 1.4E-99 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A6A12_RS03600 992c9a9af6d37d68be39cf8929815bf7 285 Pfam PF08543 Phosphomethylpyrimidine kinase 27 275 2.9E-92 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A6A12_RS02775 a47f3527f1b0c738264e17b700313c14 112 Gene3D G3DSA:3.30.70.120 1 108 1.5E-49 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A6A12_RS02775 a47f3527f1b0c738264e17b700313c14 112 PRINTS PR00340 P-II protein signature 23 41 3.8E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A6A12_RS02775 a47f3527f1b0c738264e17b700313c14 112 PRINTS PR00340 P-II protein signature 83 103 3.8E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A6A12_RS02775 a47f3527f1b0c738264e17b700313c14 112 PRINTS PR00340 P-II protein signature 52 75 3.8E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A6A12_RS02775 a47f3527f1b0c738264e17b700313c14 112 PRINTS PR00340 P-II protein signature 2 17 3.8E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A6A12_RS02775 a47f3527f1b0c738264e17b700313c14 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 A6A12_RS02775 a47f3527f1b0c738264e17b700313c14 112 PIRSF PIRSF039144 1 112 4.1E-56 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A6A12_RS02775 a47f3527f1b0c738264e17b700313c14 112 SUPERFAMILY SSF54913 1 112 1.14E-45 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A6A12_RS02775 a47f3527f1b0c738264e17b700313c14 112 SMART SM00938 4 105 3.5E-69 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A6A12_RS02775 a47f3527f1b0c738264e17b700313c14 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 A6A12_RS02775 a47f3527f1b0c738264e17b700313c14 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 3.7E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A6A12_RS08895 743e368d78d79770df9f732abd066ba6 56 Pfam PF10689 Protein of unknown function (DUF2496) 7 49 1.5E-23 T 28-03-2018 IPR019630 Protein of unknown function DUF2496, YbaM-related A6A12_RS07275 0850b3285c301d6cd7f547b208694191 157 SUPERFAMILY SSF52172 1 130 3.7E-20 T 28-03-2018 IPR011006 CheY-like superfamily A6A12_RS07275 0850b3285c301d6cd7f547b208694191 157 SMART SM00448 4 125 9.2E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS07275 0850b3285c301d6cd7f547b208694191 157 Pfam PF00072 Response regulator receiver domain 6 125 5.6E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A6A12_RS07275 0850b3285c301d6cd7f547b208694191 157 Gene3D G3DSA:3.40.50.2300 1 148 2.9E-18 T 28-03-2018 A6A12_RS10780 0f4c8da8e9fccbf8f73d58f1a34163c0 247 Pfam PF00929 Exonuclease 13 180 1.1E-37 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS10780 0f4c8da8e9fccbf8f73d58f1a34163c0 247 SMART SM00479 11 189 1.7E-50 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS10780 0f4c8da8e9fccbf8f73d58f1a34163c0 247 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 11 247 1.2E-101 T 28-03-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS10780 0f4c8da8e9fccbf8f73d58f1a34163c0 247 SUPERFAMILY SSF53098 8 190 5.81E-55 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS10780 0f4c8da8e9fccbf8f73d58f1a34163c0 247 Gene3D G3DSA:3.30.420.10 1 191 1.4E-40 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS10780 0f4c8da8e9fccbf8f73d58f1a34163c0 247 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 10 230 2.8E-82 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS14035 d78fd5dd0cc4e5dad365d576b9ae666a 184 Pfam PF04220 Der GTPase activator (YihI) 21 174 5.0E-45 T 28-03-2018 IPR007336 Der GTPase activator GO:0005096 A6A12_RS14035 d78fd5dd0cc4e5dad365d576b9ae666a 184 Hamap MF_01058 Der GTPase-activating protein YihI [yihI]. 1 177 16.445 T 28-03-2018 IPR007336 Der GTPase activator GO:0005096 A6A12_RS03810 0a87bc8def04075bff3a11de1260f67f 537 TIGRFAM TIGR04141 TIGR04141: sporadically distributed protein, TIGR04141 family 12 521 3.6E-166 T 28-03-2018 IPR026487 Sporadically distributed protein CHP04141 A6A12_RS11045 8a86f440afafc71ddf2cfbe7a671db92 335 Pfam PF02424 ApbE family 31 310 2.7E-82 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 A6A12_RS11045 8a86f440afafc71ddf2cfbe7a671db92 335 SUPERFAMILY SSF143631 23 332 1.07E-99 T 28-03-2018 IPR003374 ApbE-like domain A6A12_RS11045 8a86f440afafc71ddf2cfbe7a671db92 335 Gene3D G3DSA:3.10.520.10 27 320 1.1E-59 T 28-03-2018 A6A12_RS11045 8a86f440afafc71ddf2cfbe7a671db92 335 PIRSF PIRSF006268 1 334 4.5E-92 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 A6A12_RS14040 26a354cdaec87ae87dd972f60874c609 212 Pfam PF13489 Methyltransferase domain 62 194 2.3E-20 T 28-03-2018 A6A12_RS14040 26a354cdaec87ae87dd972f60874c609 212 SUPERFAMILY SSF53335 48 198 3.34E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS14040 26a354cdaec87ae87dd972f60874c609 212 Gene3D G3DSA:3.40.50.150 114 201 1.9E-9 T 28-03-2018 A6A12_RS14040 26a354cdaec87ae87dd972f60874c609 212 Gene3D G3DSA:3.40.50.150 3 113 6.9E-7 T 28-03-2018 A6A12_RS01960 3aee081b84806bf1827dd2bf26ee6c32 235 Pfam PF04231 Endonuclease I 34 232 4.7E-45 T 28-03-2018 IPR007346 Endonuclease I GO:0004518 A6A12_RS01960 3aee081b84806bf1827dd2bf26ee6c32 235 SUPERFAMILY SSF54060 25 233 2.24E-94 T 28-03-2018 A6A12_RS07680 cb94b7c6de2e292e3bb54572e59c5ee1 350 Gene3D G3DSA:2.130.10.10 5 344 3.3E-29 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 A6A12_RS07680 cb94b7c6de2e292e3bb54572e59c5ee1 350 SUPERFAMILY SSF51004 91 341 6.15E-29 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain A6A12_RS07680 cb94b7c6de2e292e3bb54572e59c5ee1 350 SUPERFAMILY SSF51004 31 48 6.15E-29 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain A6A12_RS07680 cb94b7c6de2e292e3bb54572e59c5ee1 350 Pfam PF10282 Lactonase, 7-bladed beta-propeller 9 340 1.1E-87 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller A6A12_RS13260 f46d27ac700f70a02b73726f13e38d1a 289 Pfam PF06251 Capsule biosynthesis GfcC 60 289 6.2E-77 T 28-03-2018 IPR010425 Domain of unknown function DUF1017 A6A12_RS14150 3905207bcacde492ffc2c8f9decd53f9 329 Gene3D G3DSA:1.10.3470.10 30 324 1.2E-29 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A6A12_RS14150 3905207bcacde492ffc2c8f9decd53f9 329 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 318 2.5E-38 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 A6A12_RS00960 6ca11606688aea73c55d6302f91ec36a 116 ProDom PD028709 MEMBRANE INNER YDGC GLPM ALGINATE BIOSYNTHESIS TRANSMEMBRANE REQUIRED FOR UNCHARACTERIZED 22 112 1.0E-32 T 28-03-2018 IPR009707 Membrane protein GlpM/YdgC A6A12_RS00960 6ca11606688aea73c55d6302f91ec36a 116 Pfam PF06942 GlpM protein 6 111 1.4E-49 T 28-03-2018 IPR009707 Membrane protein GlpM/YdgC A6A12_RS08485 577b0aed2a7a51aae7dc3f27c876027e 162 Pfam PF03245 Bacteriophage Rz lysis protein 39 158 3.3E-25 T 28-03-2018 IPR004929 Spanin, inner membrane subunit GO:0019076|GO:0019835 A6A12_RS06885 004bb0e653975a4687f55071b1a6d40a 67 PIRSF PIRSF037225 1 65 8.1E-25 T 28-03-2018 IPR017143 Uncharacterised conserved protein UCP037225 A6A12_RS06885 004bb0e653975a4687f55071b1a6d40a 67 Pfam PF14255 Cysteine-rich CPXCG 9 59 4.1E-21 T 28-03-2018 IPR025990 Cysteine-rich CPXCG protein A6A12_RS11735 a052b74d82366e285594d7a96e623432 255 Pfam PF16537 Type II secretion system protein B 190 249 4.7E-23 T 28-03-2018 IPR032389 Type II secretion system protein B A6A12_RS02855 e912899f98ab1c452b98ea28c8ea20d7 347 Pfam PF05175 Methyltransferase small domain 172 336 6.0E-57 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 A6A12_RS02855 e912899f98ab1c452b98ea28c8ea20d7 347 Gene3D G3DSA:3.40.50.150 156 347 1.0E-21 T 28-03-2018 A6A12_RS02855 e912899f98ab1c452b98ea28c8ea20d7 347 SUPERFAMILY SSF53335 159 339 5.91E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS02855 e912899f98ab1c452b98ea28c8ea20d7 347 Hamap MF_01862 Ribosomal RNA small subunit methyltransferase C [rsmC]. 4 340 45.456 T 28-03-2018 IPR023543 rRNA small subunit methyltransferase C GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS02855 e912899f98ab1c452b98ea28c8ea20d7 347 Pfam PF08468 Methyltransferase small domain N-terminal 8 163 2.4E-58 T 28-03-2018 IPR013675 Methyltransferase small, N-terminal GO:0006364|GO:0008990 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 A6A12_RS02855 e912899f98ab1c452b98ea28c8ea20d7 347 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 269 275 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A6A12_RS05290 f0d81bf0eab50a3aac2b05fe4bd140f5 156 Pfam PF12680 SnoaL-like domain 23 125 1.3E-12 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain A6A12_RS05290 f0d81bf0eab50a3aac2b05fe4bd140f5 156 SUPERFAMILY SSF54427 21 142 6.88E-23 T 28-03-2018 IPR032710 NTF2-like domain A6A12_RS05290 f0d81bf0eab50a3aac2b05fe4bd140f5 156 Gene3D G3DSA:3.10.450.50 16 138 6.6E-19 T 28-03-2018 A6A12_RS05130 1ba040d4af49f32d65803b59e3bee304 489 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 5 475 44.386 T 28-03-2018 IPR003846 Uncharacterised protein family UPF0061 A6A12_RS05130 1ba040d4af49f32d65803b59e3bee304 489 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 10 458 2.4E-152 T 28-03-2018 IPR003846 Uncharacterised protein family UPF0061 A6A12_RS05165 e9cf7e754c02411c534dab20f04d0d0e 453 PIRSF PIRSF006066 1 447 6.1E-137 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 A6A12_RS05165 e9cf7e754c02411c534dab20f04d0d0e 453 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 437 4.1E-115 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A6A12_RS05165 e9cf7e754c02411c534dab20f04d0d0e 453 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 260 9.1E-85 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 A6A12_RS03005 13ef1c9090b0f3e7a6bae52e62b00955 453 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 417 4.5E-44 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS03005 13ef1c9090b0f3e7a6bae52e62b00955 453 Pfam PF01554 MatE 22 183 1.3E-19 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS03005 13ef1c9090b0f3e7a6bae52e62b00955 453 Pfam PF01554 MatE 246 406 8.3E-13 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS03005 13ef1c9090b0f3e7a6bae52e62b00955 453 PIRSF PIRSF006603 4 441 4.7E-61 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS11100 01bc71bf0cdaa9b2f2c0829684ae097b 463 Pfam PF07690 Major Facilitator Superfamily 25 398 1.1E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A6A12_RS11100 01bc71bf0cdaa9b2f2c0829684ae097b 463 SUPERFAMILY SSF103473 11 438 4.05E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain A6A12_RS11100 01bc71bf0cdaa9b2f2c0829684ae097b 463 Gene3D G3DSA:1.20.1250.20 246 453 2.3E-13 T 28-03-2018 A6A12_RS11100 01bc71bf0cdaa9b2f2c0829684ae097b 463 Gene3D G3DSA:1.20.1250.20 3 233 4.5E-17 T 28-03-2018 A6A12_RS10455 e685340b3e4e9ef68183acf214196706 75 Pfam PF01206 Sulfurtransferase TusA 5 57 6.4E-11 T 28-03-2018 IPR001455 TusA-like domain A6A12_RS10455 e685340b3e4e9ef68183acf214196706 75 Gene3D G3DSA:3.30.110.40 2 73 5.6E-15 T 28-03-2018 IPR001455 TusA-like domain A6A12_RS10455 e685340b3e4e9ef68183acf214196706 75 SUPERFAMILY SSF64307 5 71 4.19E-11 T 28-03-2018 IPR001455 TusA-like domain A6A12_RS00155 b676ffb0f30effb5c3d15571dd052097 401 SUPERFAMILY SSF56281 6 162 3.25E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS00155 b676ffb0f30effb5c3d15571dd052097 401 SUPERFAMILY SSF56281 211 284 3.25E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS00155 b676ffb0f30effb5c3d15571dd052097 401 Gene3D G3DSA:3.60.15.10 5 306 4.1E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase A6A12_RS05690 8bab25a23adeb783d15857a71889ef70 106 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 8 101 27.751 T 28-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS A6A12_RS05690 8bab25a23adeb783d15857a71889ef70 106 SUPERFAMILY SSF54736 22 105 9.94E-32 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A6A12_RS05690 8bab25a23adeb783d15857a71889ef70 106 Gene3D G3DSA:3.30.1390.10 13 105 1.3E-36 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like A6A12_RS05690 8bab25a23adeb783d15857a71889ef70 106 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 23 102 5.5E-33 T 28-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 A6A12_RS08875 5e5e09758cf40fd61986b0dea6bb8187 329 Gene3D G3DSA:2.40.160.10 6 329 4.0E-12 T 28-03-2018 A6A12_RS08875 5e5e09758cf40fd61986b0dea6bb8187 329 SUPERFAMILY SSF56935 25 328 3.11E-15 T 28-03-2018 A6A12_RS07755 89c74bfc60dea33f57afbc239be12198 380 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 50 254 7.8E-42 T 28-03-2018 IPR017732 Type IV / VI secretion system, DotU A6A12_RS07755 89c74bfc60dea33f57afbc239be12198 380 Pfam PF09850 Type VI secretion system protein DotU 50 249 2.9E-46 T 28-03-2018 IPR017732 Type IV / VI secretion system, DotU A6A12_RS09015 5c37d8c60d35957a107be99262b62480 169 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 23 164 2.8E-46 T 28-03-2018 IPR018639 Domain of unknown function DUF2062 A6A12_RS00055 46e3aac62e09f23c0d30fe5e77a546a2 184 Pfam PF01169 Uncharacterized protein family UPF0016 103 178 1.7E-20 T 28-03-2018 IPR001727 Gdt1 family A6A12_RS00055 46e3aac62e09f23c0d30fe5e77a546a2 184 Pfam PF01169 Uncharacterized protein family UPF0016 7 80 2.0E-20 T 28-03-2018 IPR001727 Gdt1 family A6A12_RS08445 cb81ac45356ee615ab5437a786e7be0b 436 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 55 393 2.8E-90 T 28-03-2018 IPR006427 Phage portal protein, HK97 A6A12_RS08445 cb81ac45356ee615ab5437a786e7be0b 436 Pfam PF04860 Phage portal protein 62 391 1.4E-82 T 28-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein A6A12_RS01230 c0b735197fe123984b93443aae1b8ed6 295 SUPERFAMILY SSF103481 214 294 1.96E-8 T 28-03-2018 A6A12_RS01230 c0b735197fe123984b93443aae1b8ed6 295 SUPERFAMILY SSF103481 36 141 1.15E-8 T 28-03-2018 A6A12_RS01230 c0b735197fe123984b93443aae1b8ed6 295 Pfam PF00892 EamA-like transporter family 4 134 1.1E-13 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A6A12_RS01230 c0b735197fe123984b93443aae1b8ed6 295 Pfam PF00892 EamA-like transporter family 156 294 7.6E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A6A12_RS09530 5a450f1440892435fcf39c9ba3e72ed9 236 SUPERFAMILY SSF51735 3 236 1.28E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain A6A12_RS09530 5a450f1440892435fcf39c9ba3e72ed9 236 Gene3D G3DSA:3.40.50.720 1 224 8.2E-20 T 28-03-2018 A6A12_RS09530 5a450f1440892435fcf39c9ba3e72ed9 236 Pfam PF00106 short chain dehydrogenase 4 194 3.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A6A12_RS09105 98259d4e7ab0f68ca57835413b9a691d 529 TIGRFAM TIGR00774 NhaB: Na+/H+ antiporter NhaB 1 516 1.1E-302 T 28-03-2018 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 A6A12_RS09105 98259d4e7ab0f68ca57835413b9a691d 529 Pfam PF06450 Bacterial Na+/H+ antiporter B (NhaB) 1 515 5.1E-296 T 28-03-2018 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 A6A12_RS09105 98259d4e7ab0f68ca57835413b9a691d 529 Hamap MF_01599 Na(+)/H(+) antiporter NhaB [nhaB]. 1 529 376.905 T 28-03-2018 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 A6A12_RS00750 a1f181d83fc20724474f649defbcb272 151 SMART SM00360 63 135 1.9E-18 T 28-03-2018 IPR000504 RNA recognition motif domain GO:0003676 A6A12_RS00750 a1f181d83fc20724474f649defbcb272 151 SUPERFAMILY SSF54928 54 141 3.09E-25 T 28-03-2018 IPR000504 RNA recognition motif domain GO:0003676 A6A12_RS00750 a1f181d83fc20724474f649defbcb272 151 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 64 133 1.7E-16 T 28-03-2018 IPR000504 RNA recognition motif domain GO:0003676 A6A12_RS00750 a1f181d83fc20724474f649defbcb272 151 Gene3D G3DSA:3.30.70.330 47 151 1.5E-24 T 28-03-2018 A6A12_RS13275 c5eeeb5180353ea591b129b185542e44 193 Pfam PF02397 Bacterial sugar transferase 15 184 6.3E-51 T 28-03-2018 IPR003362 Bacterial sugar transferase A6A12_RS13215 91f1cd6f152229e5bb59118148276574 328 Pfam PF13439 Glycosyltransferase Family 4 45 146 4.4E-7 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 A6A12_RS13215 91f1cd6f152229e5bb59118148276574 328 Pfam PF00534 Glycosyl transferases group 1 157 296 1.9E-9 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 A6A12_RS13215 91f1cd6f152229e5bb59118148276574 328 Gene3D G3DSA:3.40.50.2000 148 300 3.2E-13 T 28-03-2018 A6A12_RS13215 91f1cd6f152229e5bb59118148276574 328 Gene3D G3DSA:3.40.50.2000 14 147 0.0015 T 28-03-2018 A6A12_RS13215 91f1cd6f152229e5bb59118148276574 328 SUPERFAMILY SSF53756 39 321 8.9E-31 T 28-03-2018 A6A12_RS02385 b7d19435da99a9c4a1839f6c9f1c2d6f 243 SUPERFAMILY SSF53448 8 230 3.47E-63 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS02385 b7d19435da99a9c4a1839f6c9f1c2d6f 243 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 105 112 - T 28-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A6A12_RS02385 b7d19435da99a9c4a1839f6c9f1c2d6f 243 Gene3D G3DSA:3.90.550.10 1 236 1.5E-52 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS02385 b7d19435da99a9c4a1839f6c9f1c2d6f 243 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 9 230 9.5E-78 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A6A12_RS02385 b7d19435da99a9c4a1839f6c9f1c2d6f 243 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 10 229 3.2E-76 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A6A12_RS02385 b7d19435da99a9c4a1839f6c9f1c2d6f 243 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 7 229 44.032 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 A6A12_RS06455 a51c7d9e149eaf7d5735094c0358a0c4 116 Pfam PF11042 Protein of unknown function (DUF2750) 13 113 2.3E-33 T 28-03-2018 IPR021284 Protein of unknown function DUF2750 A6A12_RS07520 444d7834b8403a07e00a3f9007e355fa 215 SUPERFAMILY SSF142695 34 189 1.83E-52 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A6A12_RS07520 444d7834b8403a07e00a3f9007e355fa 215 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 17 215 37.34 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A6A12_RS07520 444d7834b8403a07e00a3f9007e355fa 215 Pfam PF00925 GTP cyclohydrolase II 36 188 1.7E-57 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 A6A12_RS13060 dcc9f3e705b75eda7aa88f2f69c220f5 567 Pfam PF00474 Sodium:solute symporter family 33 298 2.2E-33 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A6A12_RS13060 dcc9f3e705b75eda7aa88f2f69c220f5 567 Pfam PF00474 Sodium:solute symporter family 368 489 2.0E-19 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A6A12_RS13060 dcc9f3e705b75eda7aa88f2f69c220f5 567 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 8 558 6.6E-262 T 28-03-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily A6A12_RS13060 dcc9f3e705b75eda7aa88f2f69c220f5 567 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 471 491 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 A6A12_RS06110 e8a6d2c74031a87eaa398663823217e7 223 SUPERFAMILY SSF52540 1 216 1.49E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS06110 e8a6d2c74031a87eaa398663823217e7 223 SMART SM00382 30 218 2.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain A6A12_RS06110 e8a6d2c74031a87eaa398663823217e7 223 Pfam PF00005 ABC transporter 21 167 1.4E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A6A12_RS06110 e8a6d2c74031a87eaa398663823217e7 223 Gene3D G3DSA:3.40.50.300 1 220 1.4E-53 T 28-03-2018 A6A12_RS06110 e8a6d2c74031a87eaa398663823217e7 223 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A6A12_RS02900 e3f1924633ad04c0366b85c92b218d96 281 Gene3D G3DSA:1.10.357.20 98 278 8.7E-42 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A6A12_RS02900 e3f1924633ad04c0366b85c92b218d96 281 Pfam PF01769 Divalent cation transporter 142 271 8.2E-28 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A6A12_RS02900 e3f1924633ad04c0366b85c92b218d96 281 SUPERFAMILY SSF161093 99 276 5.89E-45 T 28-03-2018 A6A12_RS11725 2bd2d85b10e0fcac1cea256f8a563a0b 419 Pfam PF01384 Phosphate transporter family 26 407 3.3E-112 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A6A12_RS03985 23a521df567f2a27c4ab20a604f921ad 68 ProDom PD054643 UPF0253 YAEP CYTOPLASMIC VP2335 YPO1064.1/Y3113/YP2785 VC0872 VV2574 PBPRA2947 VV11836 7 65 2.0E-25 T 28-03-2018 IPR009624 Uncharacterised protein family UPF0253 A6A12_RS03985 23a521df567f2a27c4ab20a604f921ad 68 Hamap MF_01064 UPF0253 protein YaeP [yaeP]. 1 68 29.46 T 28-03-2018 IPR009624 Uncharacterised protein family UPF0253 A6A12_RS03985 23a521df567f2a27c4ab20a604f921ad 68 Pfam PF06786 Uncharacterised protein family (UPF0253) 1 67 1.1E-36 T 28-03-2018 IPR009624 Uncharacterised protein family UPF0253 A6A12_RS08805 29c993f539a09c7e456ab2e8432aa944 227 Pfam PF01618 MotA/TolQ/ExbB proton channel family 81 207 4.7E-42 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 A6A12_RS08805 29c993f539a09c7e456ab2e8432aa944 227 TIGRFAM TIGR02796 tolQ: protein TolQ 6 220 7.2E-93 T 28-03-2018 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 A6A12_RS04830 e01d4571ae43d90a2f720c60b3b279d1 708 Pfam PF05170 AsmA family 1 599 8.0E-126 T 28-03-2018 IPR007844 AsmA A6A12_RS09340 68d740eef173079d2206defb3761360c 257 Pfam PF06629 MltA-interacting protein MipA 59 257 2.1E-42 T 28-03-2018 IPR010583 MltA-interacting MipA A6A12_RS09340 68d740eef173079d2206defb3761360c 257 Gene3D G3DSA:2.40.160.20 31 257 3.3E-4 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A6A12_RS10735 21627dcd4b2908d446893d1e57b5c0c2 46 Pfam PF11346 Protein of unknown function (DUF3149) 4 43 1.8E-16 T 28-03-2018 IPR021494 Protein of unknown function DUF3149 A6A12_RS10125 57a3f1375fa2ff23abeaaf5e6cd06261 87 Pfam PF08891 YfcL protein 5 84 1.5E-30 T 28-03-2018 IPR014987 Uncharacterised protein family YfcL A6A12_RS13335 f70d0047f552bee89f40bac1e7ea1449 128 Pfam PF04138 GtrA-like protein 14 126 4.9E-13 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 A6A12_RS02215 6f1b212f26f83e30ce42a7f5aa20b779 258 Gene3D G3DSA:3.60.21.10 1 257 1.4E-17 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A6A12_RS02215 6f1b212f26f83e30ce42a7f5aa20b779 258 SUPERFAMILY SSF56300 1 242 2.78E-17 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like A6A12_RS02215 6f1b212f26f83e30ce42a7f5aa20b779 258 Pfam PF00149 Calcineurin-like phosphoesterase 1 223 3.2E-10 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A6A12_RS02080 9cbfbe6a29b244697f3a20a0b273cdb7 1086 Gene3D G3DSA:1.20.5.1230 250 642 0.066 T 28-03-2018 A6A12_RS11645 bdea647f3f6d6448dbfce5903ae6b7d8 147 PIRSF PIRSF006318 1 136 5.3E-49 T 28-03-2018 IPR009386 Protein of unknown function DUF1043 A6A12_RS11645 bdea647f3f6d6448dbfce5903ae6b7d8 147 Pfam PF06295 Protein of unknown function (DUF1043) 6 129 2.1E-44 T 28-03-2018 IPR009386 Protein of unknown function DUF1043 A6A12_RS08365 fcbaebb12e5425306710b0b21ef2192d 199 Pfam PF06805 Bacteriophage lambda tail assembly protein I 5 88 1.8E-9 T 28-03-2018 IPR010654 Bacteriophage lambda tail assembly I A6A12_RS08365 fcbaebb12e5425306710b0b21ef2192d 199 Gene3D G3DSA:3.10.20.30 3 87 5.0E-6 T 28-03-2018 IPR012675 Beta-grasp domain A6A12_RS08520 d1248b5bb4397f47a1ba6ccf7bbadffa 335 Pfam PF06147 Protein of unknown function (DUF968) 136 332 1.8E-63 T 28-03-2018 IPR010373 Protein of unknown function DUF968 A6A12_RS08520 d1248b5bb4397f47a1ba6ccf7bbadffa 335 Gene3D G3DSA:3.30.50.20 261 332 1.1E-10 T 28-03-2018 A6A12_RS07365 737c28221e438386b00a1eed215b9cb6 1250 Pfam PF10462 Peptidase M66 357 662 1.3E-92 T 28-03-2018 IPR019503 Peptidase M66 domain GO:0004222 A6A12_RS07365 737c28221e438386b00a1eed215b9cb6 1250 Gene3D G3DSA:2.60.40.10 171 257 3.0E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS07365 737c28221e438386b00a1eed215b9cb6 1250 Pfam PF12561 ToxR activated gene A lipoprotein 728 861 8.6E-63 T 28-03-2018 IPR022218 ToxR activated gene A lipoprotein A6A12_RS07355 4ca42a450452a767fc42e6c96ba6ac7b 417 Pfam PF03222 Tryptophan/tyrosine permease family 28 380 1.2E-16 T 28-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 A6A12_RS11680 08292faa99c5adc5985fa52920e20fea 144 Pfam PF06853 Protein of unknown function (DUF1249) 27 139 4.5E-40 T 28-03-2018 IPR009659 Protein of unknown function DUF1249 A6A12_RS11845 af73b9546c089c6fc3f3570e72a7d1e7 86 Pfam PF03937 Flavinator of succinate dehydrogenase 7 77 2.2E-23 T 28-03-2018 IPR005631 Flavinator of succinate dehydrogenase A6A12_RS11845 af73b9546c089c6fc3f3570e72a7d1e7 86 Gene3D G3DSA:1.10.150.250 2 86 2.6E-23 T 28-03-2018 A6A12_RS11845 af73b9546c089c6fc3f3570e72a7d1e7 86 SUPERFAMILY SSF109910 2 79 2.75E-25 T 28-03-2018 IPR005631 Flavinator of succinate dehydrogenase A6A12_RS12130 a508b065ba28dd0dbfd3c71b35ea5059 321 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 3 311 2.6E-82 T 28-03-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 A6A12_RS12130 a508b065ba28dd0dbfd3c71b35ea5059 321 Pfam PF01699 Sodium/calcium exchanger protein 175 316 9.7E-28 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A6A12_RS12130 a508b065ba28dd0dbfd3c71b35ea5059 321 Pfam PF01699 Sodium/calcium exchanger protein 5 142 4.7E-28 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A6A12_RS07130 ae404656466b58b6a16b21a57a05810c 568 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 34 443 8.4E-84 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A6A12_RS07130 ae404656466b58b6a16b21a57a05810c 568 Pfam PF00474 Sodium:solute symporter family 34 443 2.4E-49 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 A6A12_RS10790 215d0f1a095889ca9ebd20708dca9af5 254 Pfam PF08241 Methyltransferase domain 63 125 9.9E-9 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 A6A12_RS10790 215d0f1a095889ca9ebd20708dca9af5 254 Gene3D G3DSA:3.40.50.150 53 216 2.0E-18 T 28-03-2018 A6A12_RS10790 215d0f1a095889ca9ebd20708dca9af5 254 SUPERFAMILY SSF53335 71 212 5.1E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS12730 b58fa30545b505c758dec3f2008d95c7 84 Pfam PF12292 Protein of unknown function (DUF3624) 1 79 6.7E-37 T 28-03-2018 IPR022072 Protein of unknown function DUF3624 A6A12_RS13140 25f3be3197ea951fca09b9e92039775b 229 PIRSF PIRSF028160 1 229 2.9E-100 T 28-03-2018 IPR016872 Uncharacterised conserved protein UCP028160 A6A12_RS13140 25f3be3197ea951fca09b9e92039775b 229 Pfam PF07356 Protein of unknown function (DUF1481) 33 226 5.9E-60 T 28-03-2018 IPR010858 Protein of unknown function DUF1481 A6A12_RS05160 2c87787009033b9c62b2f90ebf58b9bf 228 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 28 179 6.0E-26 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component A6A12_RS05960 5ed9965dee144ed61fc6b3ddc9724e1e 398 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 388 2.5E-118 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A6A12_RS05960 5ed9965dee144ed61fc6b3ddc9724e1e 398 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 7 389 2.1E-171 T 28-03-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 A6A12_RS05960 5ed9965dee144ed61fc6b3ddc9724e1e 398 SUPERFAMILY SSF53383 22 388 5.17E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase A6A12_RS05960 5ed9965dee144ed61fc6b3ddc9724e1e 398 PIRSF PIRSF001434 1 391 7.1E-126 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A6A12_RS05960 5ed9965dee144ed61fc6b3ddc9724e1e 398 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 199 213 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A6A12_RS05960 5ed9965dee144ed61fc6b3ddc9724e1e 398 Gene3D G3DSA:3.90.1150.10 257 391 5.0E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 A6A12_RS05960 5ed9965dee144ed61fc6b3ddc9724e1e 398 Gene3D G3DSA:3.40.640.10 4 256 6.5E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 A6A12_RS08090 850d4c2a7de10c16d587df705c45527e 110 Pfam PF03788 LrgA family 9 99 1.6E-25 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 A6A12_RS08980 55a2a1ecdc26dd9dc5ffebe8b5a9ffcd 512 Pfam PF04293 SpoVR like protein 21 451 1.6E-176 T 28-03-2018 IPR007390 Sporulation stage V, protein R A6A12_RS07875 db377efd45edbf09ae8ba13879e2f5da 72 SMART SM00530 5 67 0.0032 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A6A12_RS07875 db377efd45edbf09ae8ba13879e2f5da 72 SUPERFAMILY SSF47413 15 71 2.45E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 A6A12_RS07875 db377efd45edbf09ae8ba13879e2f5da 72 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 19 71 2.8E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A6A12_RS07875 db377efd45edbf09ae8ba13879e2f5da 72 Gene3D G3DSA:1.10.260.40 2 72 7.8E-11 T 28-03-2018 A6A12_RS10190 5a04aa985d81de260b09ea7c5cf778ea 165 Pfam PF03748 Flagellar basal body-associated protein FliL 64 165 1.2E-19 T 28-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 A6A12_RS06730 76769d6d19e9e5098fb89aeb6bdfd506 226 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 8 213 1.4E-54 T 28-03-2018 A6A12_RS02640 bf0b302ab233ded150bde0885870a144 579 Gene3D G3DSA:3.90.1640.10 49 242 4.6E-23 T 28-03-2018 A6A12_RS02640 bf0b302ab233ded150bde0885870a144 579 Pfam PF01368 DHH family 71 202 2.7E-8 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A6A12_RS02640 bf0b302ab233ded150bde0885870a144 579 Pfam PF02272 DHHA1 domain 319 451 2.2E-27 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A6A12_RS02640 bf0b302ab233ded150bde0885870a144 579 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 21 575 2.5E-158 T 28-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 A6A12_RS02640 bf0b302ab233ded150bde0885870a144 579 SUPERFAMILY SSF64182 45 463 3.01E-118 T 28-03-2018 A6A12_RS00720 d37340e318548f49c3105a740dc187c1 180 Pfam PF06114 IrrE N-terminal-like domain 46 171 3.1E-28 T 28-03-2018 IPR010359 IrrE N-terminal-like domain A6A12_RS08410 d0ef604b02434b98b646089537b72063 122 Pfam PF11367 Protein of unknown function (DUF3168) 6 91 3.3E-15 T 28-03-2018 IPR021508 Tail completion protein A6A12_RS00200 daaa58a28713183fc2ae8bc71c5095d1 319 Pfam PF11059 Protein of unknown function (DUF2860) 26 318 2.8E-98 T 28-03-2018 IPR016896 Protein of unknown function DUF2860 A6A12_RS00200 daaa58a28713183fc2ae8bc71c5095d1 319 Gene3D G3DSA:2.40.160.20 157 319 0.015 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 A6A12_RS00200 daaa58a28713183fc2ae8bc71c5095d1 319 PIRSF PIRSF028696 1 319 3.1E-98 T 28-03-2018 IPR016896 Protein of unknown function DUF2860 A6A12_RS11440 14e2e93b95b75a4c0953531eff1152d2 231 Gene3D G3DSA:3.40.50.1580 1 231 7.3E-56 T 28-03-2018 A6A12_RS11440 14e2e93b95b75a4c0953531eff1152d2 231 SUPERFAMILY SSF53167 1 230 6.68E-72 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A6A12_RS11440 14e2e93b95b75a4c0953531eff1152d2 231 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 228 2.1E-99 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A6A12_RS11440 14e2e93b95b75a4c0953531eff1152d2 231 Pfam PF01048 Phosphorylase superfamily 2 227 5.0E-48 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A6A12_RS11440 14e2e93b95b75a4c0953531eff1152d2 231 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 230 47.587 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 A6A12_RS11880 093758aa01806649410678d12bc56fe6 102 SUPERFAMILY SSF102829 6 95 2.88E-23 T 28-03-2018 IPR007838 Cell division protein ZapA-like A6A12_RS11880 093758aa01806649410678d12bc56fe6 102 Pfam PF05164 Cell division protein ZapA 6 89 3.3E-18 T 28-03-2018 IPR007838 Cell division protein ZapA-like A6A12_RS07605 bee1581daa05f4fbbbce163678a2631f 306 Pfam PF00294 pfkB family carbohydrate kinase 1 297 6.7E-68 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB A6A12_RS07605 bee1581daa05f4fbbbce163678a2631f 306 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 27 51 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A6A12_RS07605 bee1581daa05f4fbbbce163678a2631f 306 Gene3D G3DSA:3.40.1190.20 3 306 1.4E-68 T 28-03-2018 IPR029056 Ribokinase-like A6A12_RS07605 bee1581daa05f4fbbbce163678a2631f 306 SUPERFAMILY SSF53613 1 303 4.52E-80 T 28-03-2018 IPR029056 Ribokinase-like A6A12_RS07605 bee1581daa05f4fbbbce163678a2631f 306 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A6A12_RS07605 bee1581daa05f4fbbbce163678a2631f 306 PRINTS PR00990 Ribokinase signature 214 225 2.7E-7 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A6A12_RS07605 bee1581daa05f4fbbbce163678a2631f 306 PRINTS PR00990 Ribokinase signature 175 190 2.7E-7 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A6A12_RS07605 bee1581daa05f4fbbbce163678a2631f 306 PRINTS PR00990 Ribokinase signature 22 41 2.7E-7 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A6A12_RS14130 012ebcc3c89762ecc8cb9cfe1dab7d70 253 SUPERFAMILY SSF53639 22 239 6.67E-66 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A6A12_RS14130 012ebcc3c89762ecc8cb9cfe1dab7d70 253 Gene3D G3DSA:3.40.225.10 20 247 1.3E-56 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A6A12_RS14130 012ebcc3c89762ecc8cb9cfe1dab7d70 253 SMART SM01007 26 214 8.2E-60 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A6A12_RS14130 012ebcc3c89762ecc8cb9cfe1dab7d70 253 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 27 214 1.1E-43 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal A6A12_RS11380 b0872a5fdddfc957fbac72082add03b6 167 PIRSF PIRSF028680 14 167 6.4E-63 T 28-03-2018 IPR016895 Uncharacterised conserved protein UCP028680 A6A12_RS11380 b0872a5fdddfc957fbac72082add03b6 167 SUPERFAMILY SSF56935 59 160 6.41E-6 T 28-03-2018 A6A12_RS11380 b0872a5fdddfc957fbac72082add03b6 167 Gene3D G3DSA:2.40.160.40 35 167 4.7E-13 T 28-03-2018 A6A12_RS11270 1289f6e1e24728cc42492d9c36cc3918 70 Gene3D G3DSA:1.10.720.30 12 68 1.2E-31 T 28-03-2018 IPR003034 SAP domain A6A12_RS11270 1289f6e1e24728cc42492d9c36cc3918 70 Pfam PF09905 DNA-binding protein VF530 5 66 3.3E-35 T 28-03-2018 IPR018668 DNA-binding protein VF530-like GO:0003677 A6A12_RS10075 bef64587d829268acf78b5be038107eb 233 Pfam PF04172 LrgB-like family 18 228 7.1E-70 T 28-03-2018 IPR007300 CidB/LrgB family A6A12_RS04665 52aa1eafda4a88ceeddcae93b066f964 193 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 190 3.4E-62 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 A6A12_RS04665 52aa1eafda4a88ceeddcae93b066f964 193 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 3 191 2.1E-90 T 28-03-2018 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 A6A12_RS04665 52aa1eafda4a88ceeddcae93b066f964 193 PIRSF PIRSF006102 1 193 8.1E-65 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 A6A12_RS04665 52aa1eafda4a88ceeddcae93b066f964 193 Hamap MF_00459 Electron transport complex subunit RsxA [rsxA]. 2 191 26.331 T 28-03-2018 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 A6A12_RS05495 f65bc3b60e2a7c748bc9bacc85efe4c1 219 Pfam PF10014 2OG-Fe dioxygenase 25 209 2.8E-54 T 28-03-2018 IPR018724 2OG-Fe dioxygenase A6A12_RS10130 767fe4566d90a0695087c4e24ed34903 176 Pfam PF04315 Elongation factor P hydroxylase 11 172 1.0E-72 T 28-03-2018 IPR007411 Elongation factor P hydroxylase A6A12_RS02770 cab69199d4d0a7fe48ef865edf2d4b4c 128 Pfam PF06062 Uncharacterised protein family (UPF0231) 1 120 8.9E-40 T 28-03-2018 IPR008249 Uncharacterised protein family UPF0231 A6A12_RS02770 cab69199d4d0a7fe48ef865edf2d4b4c 128 PIRSF PIRSF006287 1 123 3.6E-42 T 28-03-2018 IPR008249 Uncharacterised protein family UPF0231 A6A12_RS02770 cab69199d4d0a7fe48ef865edf2d4b4c 128 ProDom PD020773 UPF0231 YACL UNCHARACTERISED UCP006287 VC0605 UNCHARACTERIZED 3'REGION VV2750 BCR OXIDASE 1 120 3.0E-35 T 28-03-2018 IPR008249 Uncharacterised protein family UPF0231 A6A12_RS05780 e1100ea0d352967a5412536afbcef748 263 Gene3D G3DSA:3.40.50.150 9 263 5.5E-38 T 28-03-2018 A6A12_RS05780 e1100ea0d352967a5412536afbcef748 263 Pfam PF13847 Methyltransferase domain 48 154 9.1E-12 T 28-03-2018 IPR025714 Methyltransferase domain A6A12_RS05780 e1100ea0d352967a5412536afbcef748 263 Hamap MF_02057 tRNA 5-carboxymethoxyuridine methyltransferase [cmoM]. 3 259 40.873 T 28-03-2018 IPR033664 tRNA 5-carboxymethoxyuridine methyltransferase GO:0008168 A6A12_RS05780 e1100ea0d352967a5412536afbcef748 263 SUPERFAMILY SSF53335 7 248 1.49E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS13905 26d31340f006b191fcbd097ab55e5709 180 Gene3D G3DSA:1.10.10.10 2 154 6.2E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS07660 99a966e60b8061cd381ddd7fef9364fd 526 PIRSF PIRSF006446 1 326 1.1E-114 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A6A12_RS07660 99a966e60b8061cd381ddd7fef9364fd 526 PIRSF PIRSF006446 354 521 8.2E-32 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A6A12_RS07660 99a966e60b8061cd381ddd7fef9364fd 526 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 502 4.0E-174 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A6A12_RS09215 9e6b84ecc834b4001d5c9c1f6a493761 306 SUPERFAMILY SSF161098 88 291 8.5E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS09215 9e6b84ecc834b4001d5c9c1f6a493761 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 4.4E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS09215 9e6b84ecc834b4001d5c9c1f6a493761 306 Gene3D G3DSA:1.10.3720.10 3 294 1.2E-38 T 28-03-2018 A6A12_RS08985 110f3f955203d6ad778dfcd16abec114 172 SUPERFAMILY SSF81342 3 170 1.49E-21 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A6A12_RS08985 110f3f955203d6ad778dfcd16abec114 172 Pfam PF01292 Prokaryotic cytochrome b561 3 170 2.2E-25 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 A6A12_RS08985 110f3f955203d6ad778dfcd16abec114 172 Gene3D G3DSA:1.20.950.20 1 172 1.8E-19 T 28-03-2018 A6A12_RS13785 7bfb70d69e861e11cbfcb9718985a24a 680 Pfam PF01432 Peptidase family M3 222 677 7.4E-166 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 A6A12_RS13785 7bfb70d69e861e11cbfcb9718985a24a 680 Gene3D G3DSA:1.20.1050.40 5 138 4.4E-40 T 28-03-2018 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal A6A12_RS13785 7bfb70d69e861e11cbfcb9718985a24a 680 SUPERFAMILY SSF55486 1 677 1.59E-212 T 28-03-2018 A6A12_RS13785 7bfb70d69e861e11cbfcb9718985a24a 680 Gene3D G3DSA:1.10.1370.10 140 434 1.8E-56 T 28-03-2018 A6A12_RS13785 7bfb70d69e861e11cbfcb9718985a24a 680 Gene3D G3DSA:1.10.1370.10 457 680 8.5E-71 T 28-03-2018 A6A12_RS05775 7f34cc35898647823e5b53fe3bdc83a6 274 Gene3D G3DSA:3.40.50.620 84 222 3.0E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A6A12_RS05775 7f34cc35898647823e5b53fe3bdc83a6 274 Pfam PF02698 DUF218 domain 89 251 1.4E-25 T 28-03-2018 IPR003848 Domain of unknown function DUF218 A6A12_RS11385 4aafd35075e4cb24c855527a2f2145a6 172 Gene3D G3DSA:3.50.30.40 15 170 3.6E-44 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein A6A12_RS11385 4aafd35075e4cb24c855527a2f2145a6 172 TIGRFAM TIGR01935 NOT-MenG: RraA family 16 164 5.0E-68 T 28-03-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 A6A12_RS11385 4aafd35075e4cb24c855527a2f2145a6 172 SUPERFAMILY SSF89562 16 169 6.41E-48 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein A6A12_RS11385 4aafd35075e4cb24c855527a2f2145a6 172 Pfam PF03737 Aldolase/RraA 16 163 1.7E-43 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein A6A12_RS00235 0b2ae024fdbfaad06a8c355095f7bef9 219 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 13 213 1.6E-69 T 28-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 A6A12_RS00235 0b2ae024fdbfaad06a8c355095f7bef9 219 Pfam PF03006 Haemolysin-III related 11 207 5.2E-39 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 A6A12_RS03990 80e15b12304c9d96ff36040626770a88 213 Gene3D G3DSA:1.10.3680.10 75 213 2.2E-17 T 28-03-2018 IPR029024 TerB-like A6A12_RS03990 80e15b12304c9d96ff36040626770a88 213 Pfam PF04391 Protein of unknown function (DUF533) 37 211 3.6E-63 T 28-03-2018 IPR007486 Inner membrane protein YebE A6A12_RS03990 80e15b12304c9d96ff36040626770a88 213 SUPERFAMILY SSF158682 71 211 2.88E-26 T 28-03-2018 A6A12_RS08795 1a43633f8fe4bd5534a548ab9e88b333 356 Pfam PF06519 TolA C-terminal 255 353 6.5E-28 T 28-03-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 A6A12_RS08795 1a43633f8fe4bd5534a548ab9e88b333 356 TIGRFAM TIGR02794 tolA_full: protein TolA 12 355 6.6E-78 T 28-03-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 A6A12_RS08795 1a43633f8fe4bd5534a548ab9e88b333 356 SUPERFAMILY SSF74653 265 356 7.65E-13 T 28-03-2018 A6A12_RS08795 1a43633f8fe4bd5534a548ab9e88b333 356 Gene3D G3DSA:3.30.1150.10 274 350 3.4E-12 T 28-03-2018 A6A12_RS06175 5458e73f0f03606e4969851504e1a56f 92 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 74 1.5E-9 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A6A12_RS06175 5458e73f0f03606e4969851504e1a56f 92 SUPERFAMILY SSF54292 3 80 2.1E-18 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 A6A12_RS06175 5458e73f0f03606e4969851504e1a56f 92 Gene3D G3DSA:3.10.20.30 1 90 4.3E-15 T 28-03-2018 IPR012675 Beta-grasp domain A6A12_RS06175 5458e73f0f03606e4969851504e1a56f 92 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 35 43 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A6A12_RS03240 63ace6423607348661ad9293e3e7794b 328 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 12 284 9.9E-82 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A6A12_RS03240 63ace6423607348661ad9293e3e7794b 328 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 3 327 45.601 T 28-03-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 A6A12_RS03240 63ace6423607348661ad9293e3e7794b 328 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 229 246 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 A6A12_RS03240 63ace6423607348661ad9293e3e7794b 328 Gene3D G3DSA:3.20.20.300 1 324 8.7E-73 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 A6A12_RS03240 63ace6423607348661ad9293e3e7794b 328 SUPERFAMILY SSF51445 2 289 3.68E-85 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily A6A12_RS00360 a641ab4b73b664a17f878c80b4865336 393 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 53 381 2.7E-98 T 28-03-2018 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX A6A12_RS06385 ddb06096a483a8ccb98422cf2a1cc1a5 169 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 24 160 2.2E-16 T 28-03-2018 IPR009936 Protein of unknown function DUF1468 A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 SUPERFAMILY SSF103088 158 287 2.49E-27 T 28-03-2018 IPR006665 OmpA-like domain A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 45 63 9.0E-148 T 28-03-2018 A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 123 145 9.0E-148 T 28-03-2018 A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 66 84 9.0E-148 T 28-03-2018 A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 104 121 9.0E-148 T 28-03-2018 A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 28 44 9.0E-148 T 28-03-2018 A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 3 27 9.0E-148 T 28-03-2018 A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 233 250 9.0E-148 T 28-03-2018 A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 148 167 9.0E-148 T 28-03-2018 A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 271 291 9.0E-148 T 28-03-2018 A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 85 103 9.0E-148 T 28-03-2018 A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 251 270 9.0E-148 T 28-03-2018 A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 174 201 9.0E-148 T 28-03-2018 A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 204 230 9.0E-148 T 28-03-2018 A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 Pfam PF00691 OmpA family 187 282 2.4E-18 T 28-03-2018 IPR006665 OmpA-like domain A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 Gene3D G3DSA:3.30.1330.60 176 291 4.6E-26 T 28-03-2018 IPR006665 OmpA-like domain A6A12_RS04625 32ee833181e352f7bc3e7eee506129f7 293 ProSitePatterns PS01068 OmpA-like domain. 220 264 - T 28-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 A6A12_RS00120 4d941d526ca6d3367d97d7e88cace3b6 804 Gene3D G3DSA:1.10.443.10 463 684 5.4E-5 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS00120 4d941d526ca6d3367d97d7e88cace3b6 804 SUPERFAMILY SSF56349 587 679 5.0E-5 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS06860 cb51ec2cd6fcc48535a179b2bf5c2815 263 Pfam PF04116 Fatty acid hydroxylase superfamily 89 225 8.6E-26 T 28-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 A6A12_RS05305 628a28e4600a0d7b24207a573b697fe8 246 Pfam PF07103 Protein of unknown function (DUF1365) 10 245 8.5E-71 T 28-03-2018 IPR010775 Protein of unknown function DUF1365 A6A12_RS13775 6db7596058fc066b2f1f7c4c66ecf893 219 Pfam PF01810 LysE type translocator 17 211 1.0E-32 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A6A12_RS13775 6db7596058fc066b2f1f7c4c66ecf893 219 PIRSF PIRSF006324 1 214 1.0E-48 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A6A12_RS12620 9012f294a685bf62bcf4412d882f77c6 580 Gene3D G3DSA:3.60.130.10 400 542 0.0015 T 28-03-2018 A6A12_RS12620 9012f294a685bf62bcf4412d882f77c6 580 Pfam PF05141 Pyoverdine/dityrosine biosynthesis protein 39 293 2.5E-60 T 28-03-2018 IPR007817 Pyoverdine biosynthesis A6A12_RS12620 9012f294a685bf62bcf4412d882f77c6 580 SUPERFAMILY SSF51197 469 541 7.78E-5 T 28-03-2018 A6A12_RS04970 7b331d39ca8ca677a05e0c7e2de21992 94 Pfam PF07023 Protein of unknown function (DUF1315) 4 83 1.4E-27 T 28-03-2018 IPR009749 Protein of unknown function DUF1315 A6A12_RS12945 a34026feed1a03d5f6b480d76eb59330 335 Gene3D G3DSA:3.30.540.10 151 335 6.0E-52 T 28-03-2018 A6A12_RS12945 a34026feed1a03d5f6b480d76eb59330 335 Gene3D G3DSA:3.30.540.10 1 147 7.5E-53 T 28-03-2018 A6A12_RS12945 a34026feed1a03d5f6b480d76eb59330 335 PIRSF PIRSF004532 1 331 7.1E-132 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A6A12_RS12945 a34026feed1a03d5f6b480d76eb59330 335 SUPERFAMILY SSF56655 1 324 8.55E-105 T 28-03-2018 A6A12_RS12945 a34026feed1a03d5f6b480d76eb59330 335 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 321 5.8E-126 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A6A12_RS12945 a34026feed1a03d5f6b480d76eb59330 335 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 330 1.9E-166 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 A6A12_RS13865 75461d8336187514124fc0e087f45494 358 Pfam PF04245 37-kD nucleoid-associated bacterial protein 18 345 1.6E-33 T 28-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 A6A12_RS02025 455011650917a677cac22a0ee7cc8e81 236 Pfam PF04402 Protein of unknown function (DUF541) 35 232 1.6E-38 T 28-03-2018 IPR007497 Protein of unknown function DUF541 A6A12_RS08400 8d9da94411b2d8d6ee87f489523006c7 147 Pfam PF16459 Phage tail assembly chaperone, TAC 8 110 8.5E-22 T 28-03-2018 IPR024410 Phage tail assembly chaperone protein, TAC A6A12_RS12895 f515b0d9db1bcfc9e58da4cca252c127 180 Gene3D G3DSA:3.30.70.1070 101 178 7.2E-12 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A6A12_RS12895 f515b0d9db1bcfc9e58da4cca252c127 180 SUPERFAMILY SSF110997 106 178 2.35E-16 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A6A12_RS12895 f515b0d9db1bcfc9e58da4cca252c127 180 Pfam PF05036 Sporulation related domain 106 175 3.7E-13 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 A6A12_RS11445 2138158960362c4f6944b83fc0de9053 317 Pfam PF03186 CobD/Cbib protein 19 283 3.7E-32 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A6A12_RS02755 61ffe7e05a1de0d3b446513f1298d0e2 379 Pfam PF02595 Glycerate kinase family 3 372 5.2E-153 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A6A12_RS02755 61ffe7e05a1de0d3b446513f1298d0e2 379 SUPERFAMILY SSF110738 1 375 3.4E-147 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A6A12_RS02755 61ffe7e05a1de0d3b446513f1298d0e2 379 PIRSF PIRSF006078 1 376 1.4E-143 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A6A12_RS02755 61ffe7e05a1de0d3b446513f1298d0e2 379 Gene3D G3DSA:3.90.1510.10 42 276 8.6E-100 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 A6A12_RS02755 61ffe7e05a1de0d3b446513f1298d0e2 379 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 375 3.4E-168 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 A6A12_RS10760 ff595b880594a2a7ea00816aa45c71e9 277 Gene3D G3DSA:3.60.20.10 1 258 5.2E-47 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A6A12_RS10760 ff595b880594a2a7ea00816aa45c71e9 277 Pfam PF13230 Glutamine amidotransferases class-II 1 256 5.0E-114 T 28-03-2018 IPR026869 Putative glutamine amidotransferase type 2 A6A12_RS10760 ff595b880594a2a7ea00816aa45c71e9 277 SUPERFAMILY SSF56235 2 253 1.46E-50 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A6A12_RS13835 d34cd149d8e4cc7d2e6cce464b0da1be 1201 Gene3D G3DSA:3.40.50.300 18 346 7.7E-8 T 28-03-2018 A6A12_RS13835 d34cd149d8e4cc7d2e6cce464b0da1be 1201 SUPERFAMILY SSF52540 63 117 5.18E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS13835 d34cd149d8e4cc7d2e6cce464b0da1be 1201 SUPERFAMILY SSF52540 233 266 5.18E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A6A12_RS05805 43df7c3fe1512461959b62ec4f0b5c65 501 Pfam PF14402 7 transmembrane helices usually fused to an inactive transglutaminase 255 498 2.3E-109 T 28-03-2018 IPR025840 7 transmembrane helices usually fused to an inactive transglutaminase A6A12_RS05805 43df7c3fe1512461959b62ec4f0b5c65 501 Pfam PF14400 Inactive transglutaminase fused to 7 transmembrane helices 25 183 3.8E-56 T 28-03-2018 IPR025838 Inactive transglutaminase fused to 7 transmembrane helices A6A12_RS08095 9dc59bfb5c4b2d993646a1395662d18b 226 Pfam PF04172 LrgB-like family 6 218 4.2E-75 T 28-03-2018 IPR007300 CidB/LrgB family A6A12_RS08095 9dc59bfb5c4b2d993646a1395662d18b 226 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 2 218 5.3E-76 T 28-03-2018 IPR005261 Conserved hypothetical protein CHP00659 A6A12_RS05925 da0f87cc72f5e04c77434b382117048e 320 SUPERFAMILY SSF161098 69 137 9.65E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS05925 da0f87cc72f5e04c77434b382117048e 320 SUPERFAMILY SSF161098 177 298 9.65E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS05925 da0f87cc72f5e04c77434b382117048e 320 Gene3D G3DSA:1.10.3720.10 4 302 6.0E-37 T 28-03-2018 A6A12_RS05925 da0f87cc72f5e04c77434b382117048e 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 314 1.9E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS10995 d8329c614d391f42a73971509ab4f9fd 431 PIRSF PIRSF005353 1 431 9.4E-184 T 28-03-2018 IPR026033 Purine permease PbuG-like A6A12_RS10995 d8329c614d391f42a73971509ab4f9fd 431 Pfam PF00860 Permease family 18 391 2.6E-53 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 A6A12_RS10805 3826306358d38ee24215c78c2d5283c5 228 Pfam PF06930 Protein of unknown function (DUF1282) 14 223 1.3E-46 T 28-03-2018 IPR009698 Protein of unknown function DUF1282 A6A12_RS08440 165ff5a9d0dcf368fadcb61a248a0d93 290 SUPERFAMILY SSF52096 35 207 1.78E-42 T 28-03-2018 IPR029045 ClpP/crotonase-like domain A6A12_RS08440 165ff5a9d0dcf368fadcb61a248a0d93 290 Gene3D G3DSA:3.90.226.10 25 216 2.6E-27 T 28-03-2018 A6A12_RS08440 165ff5a9d0dcf368fadcb61a248a0d93 290 Pfam PF00574 Clp protease 70 203 2.5E-24 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A6A12_RS08440 165ff5a9d0dcf368fadcb61a248a0d93 290 PRINTS PR00127 Clp protease catalytic subunit P signature 104 121 1.1E-9 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A6A12_RS08440 165ff5a9d0dcf368fadcb61a248a0d93 290 PRINTS PR00127 Clp protease catalytic subunit P signature 73 93 1.1E-9 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A6A12_RS08440 165ff5a9d0dcf368fadcb61a248a0d93 290 PRINTS PR00127 Clp protease catalytic subunit P signature 180 199 1.1E-9 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 A6A12_RS06180 fea8b6d4d52cd49a517e1345f434e50c 377 SUPERFAMILY SSF47240 3 341 8.96E-111 T 28-03-2018 IPR009078 Ferritin-like superfamily A6A12_RS06180 fea8b6d4d52cd49a517e1345f434e50c 377 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 115 131 - T 28-03-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A6A12_RS06180 fea8b6d4d52cd49a517e1345f434e50c 377 Gene3D G3DSA:1.10.620.20 1 347 6.3E-116 T 28-03-2018 A6A12_RS06180 fea8b6d4d52cd49a517e1345f434e50c 377 Pfam PF00268 Ribonucleotide reductase, small chain 34 333 3.1E-48 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A6A12_RS05710 e772b618421901b6a1b6011b659d7cf1 238 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 37 205 1.3E-67 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 A6A12_RS05710 e772b618421901b6a1b6011b659d7cf1 238 SUPERFAMILY SSF55729 4 232 6.36E-86 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase A6A12_RS05710 e772b618421901b6a1b6011b659d7cf1 238 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 238 87.944 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 A6A12_RS05710 e772b618421901b6a1b6011b659d7cf1 238 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 35 216 1.5E-76 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 A6A12_RS11455 c39ea356a8b3fd400cbc5727889b91d3 206 Pfam PF03458 UPF0126 domain 8 81 3.2E-22 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 A6A12_RS11455 c39ea356a8b3fd400cbc5727889b91d3 206 Pfam PF03458 UPF0126 domain 95 165 3.6E-20 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 A6A12_RS06715 aa3cb2394b5f18211c068a322c67ef3c 159 Pfam PF05751 FixH 7 147 4.1E-40 T 28-03-2018 IPR008620 Nitrogen fixation protein FixH A6A12_RS03745 c0a5bd1901e74934e291b30dfce154e3 198 Pfam PF11726 Inovirus Gp2 35 196 4.8E-26 T 28-03-2018 A6A12_RS08630 b58dc95c032314a223cd78c45c12fc5e 194 SUPERFAMILY SSF54060 89 158 2.12E-5 T 28-03-2018 A6A12_RS08630 b58dc95c032314a223cd78c45c12fc5e 194 Pfam PF13392 HNH endonuclease 113 155 6.0E-6 T 28-03-2018 IPR003615 HNH nuclease A6A12_RS01710 51520735d4613a8843b90d901128e28f 133 Pfam PF09834 Predicted membrane protein (DUF2061) 69 119 3.5E-20 T 28-03-2018 IPR018638 Domain of unknown function DUF2061, membrane A6A12_RS01710 51520735d4613a8843b90d901128e28f 133 Pfam PF09834 Predicted membrane protein (DUF2061) 4 55 2.2E-21 T 28-03-2018 IPR018638 Domain of unknown function DUF2061, membrane A6A12_RS13800 4d576b6677e6b58c988f9d54ed406e45 404 Pfam PF00589 Phage integrase family 215 380 3.7E-8 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS13800 4d576b6677e6b58c988f9d54ed406e45 404 SUPERFAMILY SSF56349 86 386 2.3E-17 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS13800 4d576b6677e6b58c988f9d54ed406e45 404 Gene3D G3DSA:1.10.443.10 189 390 2.2E-19 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS05455 19eabbe8d551175b897a3afadcb78657 251 Gene3D G3DSA:2.60.40.1500 132 240 0.0011 T 28-03-2018 A6A12_RS00140 e68750880844a9819e1860589a33d587 418 SUPERFAMILY SSF110849 114 181 8.63E-7 T 28-03-2018 IPR003115 ParB/Sulfiredoxin A6A12_RS00140 e68750880844a9819e1860589a33d587 418 Gene3D G3DSA:3.90.1530.10 109 211 9.0E-5 T 28-03-2018 A6A12_RS06230 50be08f42532539f64f4672d8d348bdb 79 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 7 77 1.9E-14 T 28-03-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 A6A12_RS06230 50be08f42532539f64f4672d8d348bdb 79 Hamap MF_00404 Probable oxaloacetate decarboxylase gamma chain [oadG]. 1 79 20.691 T 28-03-2018 IPR023424 Oxaloacetate decarboxylase gamma chain, probable GO:0008948 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 A6A12_RS06230 50be08f42532539f64f4672d8d348bdb 79 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 9 74 1.8E-10 T 28-03-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 A6A12_RS04395 075aa0ff5348889a9f39f0cf18fd6363 156 Pfam PF07295 Zinc-ribbon containing domain 15 153 1.1E-48 T 28-03-2018 IPR009912 Zinc-ribbon containing domain A6A12_RS03065 b872c31d09380ace13077aeeae1efedc 437 Pfam PF05525 Branched-chain amino acid transport protein 8 426 4.7E-151 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 A6A12_RS03065 b872c31d09380ace13077aeeae1efedc 437 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 413 5.5E-135 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 A6A12_RS07090 6b96cbfb78420a520ca17cdd64fa8342 258 Pfam PF01925 Sulfite exporter TauE/SafE 13 248 9.3E-27 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A6A12_RS04015 4817882b4151444c4cde0060bbcc1afa 149 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 30.239 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 A6A12_RS04015 4817882b4151444c4cde0060bbcc1afa 149 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 18 145 2.7E-47 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 A6A12_RS10685 3042fb2583f1e1078efa7921a19f9eeb 211 Gene3D G3DSA:3.40.50.10070 54 186 1.7E-10 T 28-03-2018 A6A12_RS10685 3042fb2583f1e1078efa7921a19f9eeb 211 PIRSF PIRSF028688 1 211 8.8E-121 T 28-03-2018 IPR014549 Flagellar protein FlgO A6A12_RS06915 63797452689ea65e9ecc3c12afe3500b 134 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 132 1.6E-29 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 A6A12_RS07455 da934054b115cf88246216650460c376 242 SMART SM00479 51 232 6.8E-26 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS07455 da934054b115cf88246216650460c376 242 Gene3D G3DSA:3.30.420.10 44 239 6.5E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS07455 da934054b115cf88246216650460c376 242 Pfam PF00929 Exonuclease 53 223 3.4E-16 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III A6A12_RS07455 da934054b115cf88246216650460c376 242 SUPERFAMILY SSF53098 45 233 8.23E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS07455 da934054b115cf88246216650460c376 242 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 49 232 1.3E-23 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A6A12_RS09990 53b304d0f38de6dbfcb683ee8a9aa78b 259 SUPERFAMILY SSF81345 2 252 3.79E-39 T 28-03-2018 IPR029022 ABC transporter, BtuC-like A6A12_RS09990 53b304d0f38de6dbfcb683ee8a9aa78b 259 Pfam PF00950 ABC 3 transport family 1 256 1.6E-75 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A6A12_RS09990 53b304d0f38de6dbfcb683ee8a9aa78b 259 Gene3D G3DSA:1.10.3470.10 1 259 1.1E-26 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like A6A12_RS04940 b673c22413959defaa0738f3972eb2f0 311 SUPERFAMILY SSF159501 29 272 9.59E-73 T 28-03-2018 A6A12_RS04940 b673c22413959defaa0738f3972eb2f0 311 PIRSF PIRSF020419 1 295 1.3E-74 T 28-03-2018 IPR016773 Ferric uptake regulator, CjrA, predicted A6A12_RS04940 b673c22413959defaa0738f3972eb2f0 311 Pfam PF04187 Haem-binding uptake, Tiki superfamily, ChaN 51 251 9.8E-59 T 28-03-2018 IPR007314 Haem-binding uptake, Tiki superfamily, ChaN A6A12_RS04260 72f0f353e2a9cb261933c14d03841251 150 PIRSF PIRSF000441 1 147 1.3E-38 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 A6A12_RS04260 72f0f353e2a9cb261933c14d03841251 150 SUPERFAMILY SSF51161 4 139 1.22E-31 T 28-03-2018 IPR011004 Trimeric LpxA-like A6A12_RS04260 72f0f353e2a9cb261933c14d03841251 150 Gene3D G3DSA:2.160.10.10 6 147 2.4E-25 T 28-03-2018 A6A12_RS04260 72f0f353e2a9cb261933c14d03841251 150 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 86 118 7.3E-8 T 28-03-2018 IPR001451 Hexapeptide repeat A6A12_RS00095 43a02e8185bb679792fa34421187c8b7 312 Gene3D G3DSA:3.20.10.10 143 303 2.2E-50 T 28-03-2018 A6A12_RS00095 43a02e8185bb679792fa34421187c8b7 312 Gene3D G3DSA:3.30.470.10 1 142 2.1E-41 T 28-03-2018 A6A12_RS00095 43a02e8185bb679792fa34421187c8b7 312 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 10 307 3.7E-143 T 28-03-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 A6A12_RS00095 43a02e8185bb679792fa34421187c8b7 312 ProSitePatterns PS00770 Aminotransferases class-IV signature. 194 223 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 A6A12_RS00095 43a02e8185bb679792fa34421187c8b7 312 Pfam PF01063 Amino-transferase class IV 36 268 3.2E-46 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A6A12_RS00095 43a02e8185bb679792fa34421187c8b7 312 SUPERFAMILY SSF56752 7 307 6.54E-103 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 A6A12_RS13290 29d0861d48ff300ee1616da44e0b21de 250 SUPERFAMILY SSF53448 41 238 1.19E-27 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS13290 29d0861d48ff300ee1616da44e0b21de 250 Pfam PF02709 N-terminal domain of galactosyltransferase 169 222 3.2E-5 T 28-03-2018 IPR027791 Galactosyltransferase, C-terminal Reactome: R-HSA-2022854|Reactome: R-HSA-975577 A6A12_RS13290 29d0861d48ff300ee1616da44e0b21de 250 Gene3D G3DSA:3.90.550.10 18 249 1.4E-20 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases A6A12_RS07815 f4cc3073f9b0b7090e05125d30e910c4 451 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 38 442 1.4E-115 T 28-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath A6A12_RS09035 b4b11f7ba1449b6bc4732b6cb517428d 189 Gene3D G3DSA:2.40.10.220 103 185 5.3E-5 T 28-03-2018 A6A12_RS07400 fa14366e1a50a21d6d0c3f8e1c122702 172 SUPERFAMILY SSF64438 13 164 1.28E-32 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic A6A12_RS07400 fa14366e1a50a21d6d0c3f8e1c122702 172 Pfam PF03975 CheD chemotactic sensory transduction 55 161 6.3E-20 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 A6A12_RS07400 fa14366e1a50a21d6d0c3f8e1c122702 172 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 6 166 19.677 T 28-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 A6A12_RS01580 164ac8706ab523a485f62b343cb7221a 214 Gene3D G3DSA:3.30.70.60 37 210 2.6E-10 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A6A12_RS01580 164ac8706ab523a485f62b343cb7221a 214 Pfam PF04612 Type II secretion system (T2SS), protein M 11 70 2.3E-7 T 28-03-2018 IPR007690 Type II secretion system, protein M GO:0009306 A6A12_RS12245 9da0f99d75c39e04347f9477e0d676d4 1265 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 928 1264 1.3E-61 T 28-03-2018 IPR007452 Translocation and assembly module TamB A6A12_RS11040 72b575c4b9ab4cc3f66ab836e993cd1a 77 Pfam PF04400 (Na+)-NQR maturation NqrM 22 63 1.1E-20 T 28-03-2018 IPR007495 (Na+)-NQR maturation factor NqrM A6A12_RS09430 85614dd026b89bec23fb67dac3f352dc 217 Gene3D G3DSA:1.25.40.10 16 216 3.5E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS09430 85614dd026b89bec23fb67dac3f352dc 217 SUPERFAMILY SSF48452 43 186 2.66E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 A6A12_RS13535 168a7a7eebcf329ee71398b3a3579d15 315 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 9 302 1.2E-74 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 A6A12_RS13535 168a7a7eebcf329ee71398b3a3579d15 315 TIGRFAM TIGR02207 lipid_A_htrB: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase 9 308 1.1E-128 T 28-03-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 A6A12_RS13535 168a7a7eebcf329ee71398b3a3579d15 315 PIRSF PIRSF026649 7 311 1.5E-77 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 A6A12_RS13535 168a7a7eebcf329ee71398b3a3579d15 315 Hamap MF_01942 Lipid A biosynthesis lauroyltransferase [lpxL]. 8 314 44.127 T 28-03-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 A6A12_RS07670 9699d359c29adc63987c03f516c1b06d 33 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 28 3.5E-18 T 28-03-2018 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 A6A12_RS07670 9699d359c29adc63987c03f516c1b06d 33 Pfam PF08173 Membrane bound YbgT-like protein 1 26 6.8E-16 T 28-03-2018 IPR012994 Membrane bound YbgT-like A6A12_RS04020 9638c76d63d6cf1b1323cb57267efd6a 95 Gene3D G3DSA:1.20.1270.70 4 94 4.9E-4 T 28-03-2018 A6A12_RS01340 19d9070212ed8b5bb4de7ad88e5a100e 239 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 30 143 3.0E-60 T 28-03-2018 IPR013559 YheO-like A6A12_RS01340 19d9070212ed8b5bb4de7ad88e5a100e 239 Pfam PF08348 YheO-like PAS domain 31 139 3.3E-35 T 28-03-2018 IPR013559 YheO-like A6A12_RS01340 19d9070212ed8b5bb4de7ad88e5a100e 239 Pfam PF13309 HTH domain 174 231 1.7E-18 T 28-03-2018 A6A12_RS01340 19d9070212ed8b5bb4de7ad88e5a100e 239 Gene3D G3DSA:1.10.10.60 169 233 1.7E-4 T 28-03-2018 A6A12_RS07975 2f216ce7ae1c7f3193d58f4caf469fa2 167 Pfam PF01863 Protein of unknown function DUF45 94 150 4.1E-11 T 28-03-2018 IPR002725 Protein of unknown function DUF45 A6A12_RS08830 496041b31d7d9361e67c560fea382100 528 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 501 4.6E-178 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A6A12_RS08830 496041b31d7d9361e67c560fea382100 528 PIRSF PIRSF006446 1 331 2.8E-116 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A6A12_RS08830 496041b31d7d9361e67c560fea382100 528 PIRSF PIRSF006446 353 526 1.8E-33 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 A6A12_RS00600 0125ea8c58204d1b415f7f49396cfadf 447 TIGRFAM TIGR00797 matE: MATE efflux family protein 24 418 1.1E-68 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS00600 0125ea8c58204d1b415f7f49396cfadf 447 Pfam PF01554 MatE 251 399 1.1E-13 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS00600 0125ea8c58204d1b415f7f49396cfadf 447 Pfam PF01554 MatE 24 184 5.3E-23 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS06750 0dff0887f2b119924735c6bc91988bc8 220 Pfam PF11205 Protein of unknown function (DUF2987) 23 166 1.3E-53 T 28-03-2018 IPR021370 Protein of unknown function DUF2987 A6A12_RS01170 8c3b25a6f6193468208b94f0c4715471 233 Pfam PF00687 Ribosomal protein L1p/L10e family 30 219 1.9E-51 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein A6A12_RS01170 8c3b25a6f6193468208b94f0c4715471 233 SUPERFAMILY SSF56808 6 226 3.01E-82 T 28-03-2018 IPR023674 Ribosomal protein L1-like A6A12_RS01170 8c3b25a6f6193468208b94f0c4715471 233 Gene3D G3DSA:3.30.190.20 150 228 4.1E-21 T 28-03-2018 A6A12_RS01170 8c3b25a6f6193468208b94f0c4715471 233 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 1.3E-107 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A6A12_RS01170 8c3b25a6f6193468208b94f0c4715471 233 PIRSF PIRSF002155 1 227 7.5E-80 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS01170 8c3b25a6f6193468208b94f0c4715471 233 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.514 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 A6A12_RS01170 8c3b25a6f6193468208b94f0c4715471 233 Gene3D G3DSA:3.40.50.790 68 149 1.7E-34 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich A6A12_RS01170 8c3b25a6f6193468208b94f0c4715471 233 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A6A12_RS05315 c73ea5cb3f2af55d90c349c7efe7b826 165 Pfam PF11086 Protein of unknown function (DUF2878) 6 149 2.0E-31 T 28-03-2018 IPR021306 Protein of unknown function DUF2878 A6A12_RS02170 0a38dd5825e087f6bc4116d3b6c0c96e 356 Pfam PF15935 RNase LS, bacterial toxin 97 324 8.3E-87 T 28-03-2018 IPR031845 Bacterial toxin, RNase RnlA/LsoA A6A12_RS09450 df6b64e6b43a18fa17369a5ebbe994a7 202 Pfam PF12261 Thermostable hemolysin 18 188 5.9E-61 T 28-03-2018 IPR022050 Thermostable hemolysin A6A12_RS09450 df6b64e6b43a18fa17369a5ebbe994a7 202 Gene3D G3DSA:3.40.630.30 49 162 0.011 T 28-03-2018 A6A12_RS00700 d5b8e964f800a6704dd24e6b3e080340 439 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 17 111 1.2E-18 T 28-03-2018 IPR017508 HipA, N-terminal subdomain 1 A6A12_RS00700 d5b8e964f800a6704dd24e6b3e080340 439 Pfam PF13657 HipA N-terminal domain 17 111 3.5E-14 T 28-03-2018 IPR017508 HipA, N-terminal subdomain 1 A6A12_RS00700 d5b8e964f800a6704dd24e6b3e080340 439 Pfam PF07804 HipA-like C-terminal domain 153 402 1.1E-48 T 28-03-2018 IPR012893 HipA-like, C-terminal A6A12_RS03840 22a00596c0ed107b69540014ec51ea40 291 Gene3D G3DSA:3.40.1800.10 33 132 6.2E-13 T 28-03-2018 A6A12_RS12340 4763133f2a8108c8e9f74eebc3118391 145 Pfam PF04945 YHS domain 38 83 9.5E-9 T 28-03-2018 IPR007029 YHS domain A6A12_RS12340 4763133f2a8108c8e9f74eebc3118391 145 Gene3D G3DSA:1.10.620.20 35 143 2.5E-6 T 28-03-2018 A6A12_RS11205 21c225b3f0d3034281ce9fccb9134ccc 394 Pfam PF05940 NnrS protein 16 388 2.5E-105 T 28-03-2018 IPR010266 NnrS A6A12_RS12870 6e89a514d7d5763feac319ad3558ec13 445 Pfam PF01554 MatE 245 406 9.5E-20 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS12870 6e89a514d7d5763feac319ad3558ec13 445 Pfam PF01554 MatE 22 180 6.4E-27 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS12870 6e89a514d7d5763feac319ad3558ec13 445 PIRSF PIRSF006603 1 443 3.7E-128 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS12870 6e89a514d7d5763feac319ad3558ec13 445 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 410 7.2E-57 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A6A12_RS04710 6d3121aa357f7ca5f74b37fc11b32952 345 SUPERFAMILY SSF47336 256 328 3.93E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A6A12_RS04710 6d3121aa357f7ca5f74b37fc11b32952 345 PIRSF PIRSF001111 39 330 7.8E-122 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 A6A12_RS04710 6d3121aa357f7ca5f74b37fc11b32952 345 Gene3D G3DSA:3.40.50.850 39 246 5.2E-47 T 28-03-2018 A6A12_RS04710 6d3121aa357f7ca5f74b37fc11b32952 345 SUPERFAMILY SSF52499 36 246 7.33E-61 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A6A12_RS04710 6d3121aa357f7ca5f74b37fc11b32952 345 PRINTS PR01398 Isochorismatase signature 40 52 3.3E-43 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 A6A12_RS04710 6d3121aa357f7ca5f74b37fc11b32952 345 PRINTS PR01398 Isochorismatase signature 221 238 3.3E-43 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 A6A12_RS04710 6d3121aa357f7ca5f74b37fc11b32952 345 PRINTS PR01398 Isochorismatase signature 203 221 3.3E-43 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 A6A12_RS04710 6d3121aa357f7ca5f74b37fc11b32952 345 PRINTS PR01398 Isochorismatase signature 118 137 3.3E-43 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 A6A12_RS04710 6d3121aa357f7ca5f74b37fc11b32952 345 PRINTS PR01398 Isochorismatase signature 147 169 3.3E-43 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 A6A12_RS04710 6d3121aa357f7ca5f74b37fc11b32952 345 PRINTS PR01398 Isochorismatase signature 101 118 3.3E-43 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 A6A12_RS04710 6d3121aa357f7ca5f74b37fc11b32952 345 Pfam PF00550 Phosphopantetheine attachment site 258 317 6.6E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A6A12_RS04710 6d3121aa357f7ca5f74b37fc11b32952 345 Gene3D G3DSA:1.10.1200.10 255 339 8.9E-10 T 28-03-2018 A6A12_RS04710 6d3121aa357f7ca5f74b37fc11b32952 345 Pfam PF00857 Isochorismatase family 70 239 8.2E-37 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 A6A12_RS10280 fc2d3c86386027196f1928b63d9fe2d9 300 SUPERFAMILY SSF54909 1 297 2.32E-94 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel A6A12_RS10280 fc2d3c86386027196f1928b63d9fe2d9 300 Pfam PF04261 Dyp-type peroxidase family 5 293 3.9E-89 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 A6A12_RS10280 fc2d3c86386027196f1928b63d9fe2d9 300 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 5 293 2.4E-85 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 A6A12_RS02305 5e2ff48f33e383e4a1c806d7fec33356 376 Pfam PF14350 Beta protein 8 350 5.9E-71 T 28-03-2018 IPR025683 Protein beta A6A12_RS08535 95ecac9128eda9d5b18b30480caa504f 163 Gene3D G3DSA:3.30.420.10 3 158 0.008 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 A6A12_RS05105 6145ceab30f4b2f4d316a3fa2076dce1 511 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 10 488 5.0E-122 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 A6A12_RS08425 8551a8f8bd9a715fa56b04734fa2ca46 102 Pfam PF05135 Phage gp6-like head-tail connector protein 4 78 2.3E-9 T 28-03-2018 IPR021146 Phage gp6-like head-tail connector protein A6A12_RS08425 8551a8f8bd9a715fa56b04734fa2ca46 102 Gene3D G3DSA:1.10.3230.10 2 94 4.8E-4 T 28-03-2018 A6A12_RS05950 a1ff466878fe7755c6a31c80333d8e91 129 Pfam PF04024 PspC domain 4 62 5.8E-15 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal A6A12_RS05950 a1ff466878fe7755c6a31c80333d8e91 129 TIGRFAM TIGR02978 phageshock_pspC: phage shock protein C 3 129 1.7E-47 T 28-03-2018 IPR014320 Phage shock protein, PspC A6A12_RS10480 8a562c55197c28317e6dbc80ce7f9c34 395 Pfam PF09839 Uncharacterized protein conserved in bacteria (DUF2066) 32 263 2.0E-71 T 28-03-2018 IPR018642 Protein of unknown function DUF2066 A6A12_RS00715 534891c5400444e26d19a0629209aadf 219 Gene3D G3DSA:1.20.5.340 138 207 7.9E-4 T 28-03-2018 A6A12_RS09265 a042916ce8a11e752437f93c258652f5 86 Pfam PF00550 Phosphopantetheine attachment site 7 80 7.2E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A6A12_RS09265 a042916ce8a11e752437f93c258652f5 86 SUPERFAMILY SSF47336 6 84 2.09E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain A6A12_RS09265 a042916ce8a11e752437f93c258652f5 86 Gene3D G3DSA:1.10.1200.10 3 86 1.8E-18 T 28-03-2018 A6A12_RS12285 09854305318ab11a8a9470ae5ebdbd4e 166 Pfam PF11736 Protein of unknown function (DUF3299) 31 161 5.5E-44 T 28-03-2018 IPR021727 Protein of unknown function DUF3299 A6A12_RS06940 9ad8ce2c633fa47c4cfc4471bd1c6795 235 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 231 8.5E-36 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A6A12_RS06940 9ad8ce2c633fa47c4cfc4471bd1c6795 235 SUPERFAMILY SSF51695 2 233 3.14E-66 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A6A12_RS06940 9ad8ce2c633fa47c4cfc4471bd1c6795 235 Gene3D G3DSA:3.20.20.190 1 235 1.2E-65 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 A6A12_RS00570 9ff9cc77594592b1eb69cab0c671bce5 135 Pfam PF03748 Flagellar basal body-associated protein FliL 33 135 4.7E-19 T 28-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 A6A12_RS05975 6d92724ffe78096a8341ec591e8bafd5 231 Gene3D G3DSA:3.30.2350.10 1 201 1.2E-47 T 28-03-2018 A6A12_RS05975 6d92724ffe78096a8341ec591e8bafd5 231 SUPERFAMILY SSF55120 2 196 2.3E-45 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS05975 6d92724ffe78096a8341ec591e8bafd5 231 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 47 61 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS05975 6d92724ffe78096a8341ec591e8bafd5 231 TIGRFAM TIGR01621 RluA-like: pseudouridine synthase Rlu family protein, TIGR01621 1 220 2.0E-106 T 28-03-2018 IPR006508 Pseudouridine synthase, RluA-like A6A12_RS05975 6d92724ffe78096a8341ec591e8bafd5 231 Pfam PF00849 RNA pseudouridylate synthase 10 153 5.9E-25 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 A6A12_RS12630 3ef3272a703f1e9fb8133af311cc4490 297 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 24 280 3.7E-42 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 A6A12_RS12630 3ef3272a703f1e9fb8133af311cc4490 297 SUPERFAMILY SSF51197 27 282 1.51E-56 T 28-03-2018 A6A12_RS12630 3ef3272a703f1e9fb8133af311cc4490 297 Gene3D G3DSA:3.60.130.10 7 295 4.0E-52 T 28-03-2018 A6A12_RS07515 a34c5764fa6fcd077560177c10709a21 420 Pfam PF09375 Imelysin 40 398 3.3E-96 T 28-03-2018 IPR018976 Peptidase M75, Imelysin A6A12_RS08030 d822fe8eeddd1a3810d9ddf241c00ef4 266 Pfam PF02654 Cobalamin-5-phosphate synthase 15 249 1.5E-50 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A6A12_RS08030 d822fe8eeddd1a3810d9ddf241c00ef4 266 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 10 249 6.6E-34 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A6A12_RS08030 d822fe8eeddd1a3810d9ddf241c00ef4 266 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 266 45.786 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 A6A12_RS02550 d26a0ed78fe2345da620a7e3d03041ca 264 Pfam PF01578 Cytochrome C assembly protein 40 262 5.5E-44 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 A6A12_RS06240 d765e539539266e1b3a3ab3bb19fdbb8 434 PIRSF PIRSF015658 1 432 1.7E-171 T 28-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 A6A12_RS06240 d765e539539266e1b3a3ab3bb19fdbb8 434 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 20 430 2.0E-156 T 28-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 A6A12_RS06240 d765e539539266e1b3a3ab3bb19fdbb8 434 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 19 426 9.4E-177 T 28-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 A6A12_RS06380 a2a5605f97dae9c32dba23251d861796 508 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 18 444 8.7E-139 T 28-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane A6A12_RS14385 ef1e8002d670fcac8490c0fe492a2866 129 Pfam PF03899 ATP synthase I chain 15 111 1.4E-19 T 28-03-2018 IPR005598 ATP synthase protein I A6A12_RS03975 cd5436e57be0ececc0949b34f6228cf0 81 Pfam PF12286 Protein of unknown function (DUF3622) 1 73 1.4E-32 T 28-03-2018 IPR022069 Protein of unknown function DUF3622 A6A12_RS02760 337d40edcf23ae81e0947349a32fe968 421 Pfam PF02447 GntP family permease 9 414 1.4E-22 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 A6A12_RS12855 fac501a7ec0a28c65a1022651c1fe7c1 155 Pfam PF05656 Protein of unknown function (DUF805) 22 154 7.7E-22 T 28-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 A6A12_RS12995 461f5aea31961c34b5bde6dbed313db7 437 PIRSF PIRSF004539 1 437 3.0E-179 T 28-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A6A12_RS12995 461f5aea31961c34b5bde6dbed313db7 437 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 5 436 4.8E-179 T 28-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A6A12_RS12995 461f5aea31961c34b5bde6dbed313db7 437 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 5 369 1.1E-151 T 28-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 A6A12_RS00975 bd8efcd267dd52dedd055ca244a56b29 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 1.5E-17 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain A6A12_RS00975 bd8efcd267dd52dedd055ca244a56b29 96 Gene3D G3DSA:3.30.70.100 1 84 2.6E-19 T 28-03-2018 A6A12_RS00975 bd8efcd267dd52dedd055ca244a56b29 96 SUPERFAMILY SSF54909 2 81 1.98E-23 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel A6A12_RS13300 16d8c4e235b311378ddd6ea7809b88c3 304 Pfam PF05045 Rhamnan synthesis protein F 74 213 1.1E-6 T 28-03-2018 IPR007739 Rhamnan synthesis F A6A12_RS13395 67f9b180acbc459ce88780a3f9e10792 268 Pfam PF01061 ABC-2 type transporter 18 225 1.6E-27 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A6A12_RS14010 6c8dbbe30cc4f57a3c018a37ec6a004d 83 Pfam PF04380 Membrane fusogenic activity 1 78 1.8E-27 T 28-03-2018 IPR007475 Membrane fusogenic activity A6A12_RS05465 74684ad67143b6c06dae894234c52a83 247 Pfam PF03640 Secreted repeat of unknown function 150 182 1.4E-7 T 28-03-2018 IPR005297 Lipoprotein repeat A6A12_RS05465 74684ad67143b6c06dae894234c52a83 247 Pfam PF03640 Secreted repeat of unknown function 92 132 8.1E-16 T 28-03-2018 IPR005297 Lipoprotein repeat A6A12_RS05465 74684ad67143b6c06dae894234c52a83 247 Pfam PF03640 Secreted repeat of unknown function 34 73 1.7E-10 T 28-03-2018 IPR005297 Lipoprotein repeat A6A12_RS05465 74684ad67143b6c06dae894234c52a83 247 Pfam PF03640 Secreted repeat of unknown function 204 246 8.9E-17 T 28-03-2018 IPR005297 Lipoprotein repeat A6A12_RS00470 a9e45dfd6141731dfea58cdd1bbd632b 207 Pfam PF07947 YhhN family 26 205 7.1E-35 T 28-03-2018 IPR012506 YhhN-like GO:0016021 A6A12_RS05590 9611cf11fc3ad22c3b1a5a8d59f90104 419 Pfam PF06097 Bacterial protein of unknown function (DUF945) 5 409 3.2E-42 T 28-03-2018 IPR010352 Protein of unknown function DUF945 A6A12_RS06325 4c2735df0416d1d74c734f7e9d155bbf 92 Hamap MF_00674 UPF0251 protein . 2 92 22.316 T 28-03-2018 IPR002852 Uncharacterised protein family UPF0251 A6A12_RS06325 4c2735df0416d1d74c734f7e9d155bbf 92 Pfam PF02001 Protein of unknown function DUF134 2 89 2.5E-20 T 28-03-2018 IPR002852 Uncharacterised protein family UPF0251 A6A12_RS06325 4c2735df0416d1d74c734f7e9d155bbf 92 Gene3D G3DSA:1.10.10.10 5 84 1.4E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS06325 4c2735df0416d1d74c734f7e9d155bbf 92 SUPERFAMILY SSF88659 34 82 2.18E-5 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A6A12_RS01915 0a1b8283caab8aee5839dfe9de03c503 185 Pfam PF02325 YGGT family 10 77 9.3E-19 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 A6A12_RS01915 0a1b8283caab8aee5839dfe9de03c503 185 Pfam PF02325 YGGT family 109 173 2.8E-19 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 A6A12_RS08245 bb15a0bdff8cf917755f3961427d1207 163 Pfam PF04191 Phospholipid methyltransferase 53 152 1.6E-14 T 28-03-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 A6A12_RS08245 bb15a0bdff8cf917755f3961427d1207 163 ProDom PD049902 METHYLTRANSFERASE TRANSFERASE PRECURSOR ISOPRENYLCYSTEINE SIGNAL CARBOXYL TRANSMEMBRANE MEMBRANE FAMILY XCC3183 118 163 1.0E-10 T 28-03-2018 A6A12_RS08885 695eb1a73a93bea2ee79a722ad298d02 259 Pfam PF01925 Sulfite exporter TauE/SafE 12 250 1.6E-45 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A6A12_RS00655 6c0523398e4b336e571eea8db5393cd0 178 Gene3D G3DSA:1.10.287.620 2 142 6.7E-5 T 28-03-2018 A6A12_RS00455 371ccf2d7cb8bb6e195828f3af3f323d 109 Pfam PF10694 Protein of unknown function (DUF2500) 3 105 1.6E-26 T 28-03-2018 IPR019635 Protein of unknown function DUF2500 A6A12_RS09750 02e2fbc59712a1fdbe1388c494ef541d 481 Pfam PF03553 Na+/H+ antiporter family 161 453 1.3E-66 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A6A12_RS09750 02e2fbc59712a1fdbe1388c494ef541d 481 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 7 457 1.5E-161 T 28-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 A6A12_RS06330 21bb65fbf058b40744b2bda473b17480 67 Pfam PF04400 (Na+)-NQR maturation NqrM 21 63 1.9E-19 T 28-03-2018 IPR007495 (Na+)-NQR maturation factor NqrM A6A12_RS00130 172d9b8a9ce859bd46b90b18391e6f6e 454 Gene3D G3DSA:1.10.150.130 43 195 4.8E-5 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal A6A12_RS00130 172d9b8a9ce859bd46b90b18391e6f6e 454 SUPERFAMILY SSF56349 185 338 3.53E-19 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A6A12_RS00130 172d9b8a9ce859bd46b90b18391e6f6e 454 Pfam PF00589 Phage integrase family 193 336 3.6E-13 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS00130 172d9b8a9ce859bd46b90b18391e6f6e 454 Gene3D G3DSA:1.10.443.10 196 388 1.5E-22 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 A6A12_RS06040 1c75d09d32f3a4daa4fa4a037fcb0eb0 206 Pfam PF01810 LysE type translocator 15 205 1.7E-26 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A6A12_RS06040 1c75d09d32f3a4daa4fa4a037fcb0eb0 206 PIRSF PIRSF006324 1 206 8.3E-44 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A6A12_RS07655 c1d82bfdfe752cb87c224ed88d49dca2 199 Pfam PF07681 DoxX 24 111 1.2E-15 T 28-03-2018 IPR032808 DoxX family A6A12_RS04125 c55b1ad28fc1249bdcf0605d81e51a38 258 PIRSF PIRSF029037 1 258 2.9E-114 T 28-03-2018 IPR016908 Uncharacterised conserved protein UCP029037 A6A12_RS04125 c55b1ad28fc1249bdcf0605d81e51a38 258 Pfam PF10071 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) 1 256 4.4E-113 T 28-03-2018 IPR016908 Uncharacterised conserved protein UCP029037 A6A12_RS09275 0a73b6f05bc6f2e18f21b16045282fde 185 Pfam PF04279 Intracellular septation protein A 15 158 2.1E-6 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 A6A12_RS04470 6755d8f82bf906fde308231461fbc011 265 Pfam PF09829 Uncharacterized protein conserved in bacteria (DUF2057) 24 220 7.5E-47 T 28-03-2018 IPR018635 Uncharacterised protein family UPF0319 A6A12_RS05430 822a9022848238ede3296890cf541819 45 Pfam PF08056 Tryptophan operon leader peptide 10 45 2.8E-10 T 28-03-2018 IPR012639 Tryptophan operon leader peptide A6A12_RS13945 2f7545082134a180df241c810277dbef 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 318 2.3E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS13945 2f7545082134a180df241c810277dbef 325 SUPERFAMILY SSF161098 89 302 2.49E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 A6A12_RS13945 2f7545082134a180df241c810277dbef 325 Gene3D G3DSA:1.10.3720.10 3 308 1.3E-36 T 28-03-2018 A6A12_RS07040 6ec7efad090c09d73cabe976b26aa6e8 117 Gene3D G3DSA:1.20.5.400 32 104 1.1E-4 T 28-03-2018 A6A12_RS06160 07429e73f063d63db02a28baccc54d00 299 Pfam PF13084 Domain of unknown function (DUF3943) 136 245 1.9E-37 T 28-03-2018 IPR025079 Domain of unknown function DUF3943 A6A12_RS04090 dae66370ac03a3eff5a877374f31a869 363 PIRSF PIRSF028774 1 362 1.1E-189 T 28-03-2018 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 A6A12_RS04090 dae66370ac03a3eff5a877374f31a869 363 Gene3D G3DSA:3.40.50.150 178 359 1.1E-18 T 28-03-2018 A6A12_RS04090 dae66370ac03a3eff5a877374f31a869 363 Pfam PF01728 FtsJ-like methyltransferase 188 280 3.2E-6 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 A6A12_RS04090 dae66370ac03a3eff5a877374f31a869 363 SUPERFAMILY SSF53335 186 281 9.0E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A6A12_RS04090 dae66370ac03a3eff5a877374f31a869 363 Hamap MF_01551 Ribosomal RNA large subunit methyltransferase M [rlmM]. 1 357 84.865 T 28-03-2018 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 A6A12_RS06845 9fd1bdcf2635efe5ea425c59b9b85288 91 Pfam PF11173 Protein of unknown function (DUF2960) 1 77 4.3E-37 T 28-03-2018 IPR021343 Protein of unknown function DUF2960 A6A12_RS05575 ffbca7718c89cf2b172fac394edb97d1 182 Gene3D G3DSA:2.40.160.40 53 179 1.6E-4 T 28-03-2018 A6A12_RS03025 ad52c1c76004318261b10985400cbfc9 175 SUPERFAMILY SSF55718 45 139 1.81E-18 T 28-03-2018 IPR003033 SCP2 sterol-binding domain A6A12_RS03025 ad52c1c76004318261b10985400cbfc9 175 Gene3D G3DSA:3.30.1050.10 24 141 1.8E-14 T 28-03-2018 IPR003033 SCP2 sterol-binding domain A6A12_RS03025 ad52c1c76004318261b10985400cbfc9 175 Pfam PF02036 SCP-2 sterol transfer family 44 134 7.2E-19 T 28-03-2018 IPR003033 SCP2 sterol-binding domain A6A12_RS03025 ad52c1c76004318261b10985400cbfc9 175 PIRSF PIRSF025550 1 174 5.9E-81 T 28-03-2018 IPR016830 Uncharacterised conserved protein UCP025550, lipid carrier protein, YhbT A6A12_RS04925 1bcff854ad4f99911605c8bb1b1cc86c 82 Pfam PF03692 Putative zinc- or iron-chelating domain 2 59 5.1E-6 T 28-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A6A12_RS13265 7302674889ee3c27380e504d52991710 736 Pfam PF06082 Exopolysaccharide biosynthesis protein YbjH 45 723 4.3E-253 T 28-03-2018 IPR010344 Exopolysaccharide biosynthesis protein YbjH A6A12_RS07650 28e6618233e653089f0ad7a596c7d5c2 248 Pfam PF09836 Putative DNA-binding domain 32 89 8.3E-6 T 28-03-2018 IPR018640 Putative DNA-binding domain, bacteria A6A12_RS08890 4149afefff28333cff5fb27a146c2af8 187 Pfam PF07445 Primosomal replication protein priC 10 184 1.8E-51 T 28-03-2018 IPR010890 Primosomal replication PriB/PriC A6A12_RS03735 32c8d58d5bc50e029bd90d0560519005 225 Pfam PF11726 Inovirus Gp2 38 223 5.6E-66 T 28-03-2018 A6A12_RS13595 d692f13047df2026e411ba9e2737d9f8 245 Gene3D G3DSA:1.10.10.10 2 242 6.8E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain A6A12_RS08405 144d110f1365d081b248868778a6b4c0 158 Pfam PF16460 Phage tail tube, TTP, lambda-like 26 156 2.5E-53 T 28-03-2018 IPR032495 Phage tail tube protein, lambda-like A6A12_RS11295 a3f61941d21a732f0c6e8fa88a9b53ef 205 Pfam PF10144 Bacterial virulence factor haemolysin 6 151 6.7E-40 T 28-03-2018 IPR019305 Uncharacterised protein family Smp A6A12_RS02525 f133189b868e462eba4f75aa1b76e7cd 153 Pfam PF09335 SNARE associated Golgi protein 51 149 1.3E-12 T 28-03-2018 IPR032816 SNARE associated Golgi protein A6A12_RS06215 a417110f6106e169aba75d39eaa1cc8a 501 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 440 9.0E-145 T 28-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane A6A12_RS09405 36667c09394d6629900dcc771481b680 194 Pfam PF01810 LysE type translocator 17 187 1.6E-16 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A6A12_RS13930 733207ac99dbfbbe0d3314aa4fb368e2 249 Gene3D G3DSA:1.20.5.400 103 180 3.1E-4 T 28-03-2018 A6A12_RS02015 57a15face12332ce06cf5cfa2b5cf294 210 Pfam PF01810 LysE type translocator 15 201 3.6E-40 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 A6A12_RS06980 e8721496501b2d44c5afa5a33c822e97 244 Gene3D G3DSA:1.20.5.400 81 149 6.7E-4 T 28-03-2018 A6A12_RS06980 e8721496501b2d44c5afa5a33c822e97 244 Gene3D G3DSA:1.20.5.400 36 77 0.048 T 28-03-2018 A6A12_RS10285 b7bdd3790efee6ffbf2ce5e55e821476 155 Pfam PF11143 Protein of unknown function (DUF2919) 4 148 1.7E-54 T 28-03-2018 IPR021318 Protein of unknown function DUF2919 A6A12_RS02075 c53b57a6b964a885a67a43e788a79489 295 Pfam PF13503 Domain of unknown function (DUF4123) 27 136 3.8E-17 T 28-03-2018 IPR025391 Domain of unknown function DUF4123 A6A12_RS11090 7c405b658f3958007d6fc9f4d39d233c 189 Pfam PF03923 Uncharacterized lipoprotein 28 186 2.3E-52 T 28-03-2018 IPR005619 Uncharacterised protein family, YajG A6A12_RS04185 afa05d66c6711d834dd178896fe2de78 255 Gene3D G3DSA:2.60.40.10 31 129 1.0E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold A6A12_RS03110 f6aa0b712d7303c33ae20969b63b2f52 263 Pfam PF01925 Sulfite exporter TauE/SafE 10 261 3.5E-50 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A6A12_RS01775 388fa75f29765709e4ffab5378e10e93 253 Pfam PF06738 Putative threonine/serine exporter 10 247 1.6E-68 T 28-03-2018 IPR010619 Putative threonine/serine exporter A6A12_RS06210 1d9c174629c8b5e5ffeed55cf4c53f60 164 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 15 158 6.2E-20 T 28-03-2018 IPR009936 Protein of unknown function DUF1468 A6A12_RS05720 e45a0897fe47fc9d8b9bacf8abbaddf8 83 Pfam PF10692 Protein of unknown function (DUF2498) 3 80 6.9E-40 T 28-03-2018 IPR019633 Protein of unknown function DUF2498 A6A12_RS08420 1f332d3bd93ed3f8774cb95ffec308fc 122 Pfam PF05521 Phage head-tail joining protein 8 113 5.8E-14 T 28-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor A6A12_RS12985 f5a6184b4054a9d30c6b25d9b14a802e 181 Pfam PF04186 FxsA cytoplasmic membrane protein 21 128 1.5E-34 T 28-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 A6A12_RS10320 da38052615d96d17bcc8fe2dd9ef927a 69 Pfam PF11446 Protein of unknown function (DUF2897) 15 61 2.5E-16 T 28-03-2018 IPR021550 Protein of unknown function DUF2897 A6A12_RS12005 aaad35a880c3b39bff9921cf73b98018 356 Pfam PF03739 Predicted permease YjgP/YjgQ family 8 354 2.3E-69 T 28-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 A6A12_RS12005 aaad35a880c3b39bff9921cf73b98018 356 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 354 2.4E-131 T 28-03-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 A6A12_RS06945 75c2b9f7c35ed7d1928379b54198f0fe 277 Pfam PF02517 CAAX protease self-immunity 175 263 3.6E-13 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A6A12_RS00240 da1b5011cfb3d9b0fd826bbca8e09f6c 181 Pfam PF11355 Protein of unknown function (DUF3157) 6 179 3.2E-51 T 28-03-2018 IPR021501 Protein of unknown function DUF3157 A6A12_RS13000 45fd28e2d84ebca8163846492871fda4 481 Pfam PF03606 C4-dicarboxylate anaerobic carrier 20 475 1.2E-137 T 28-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 A6A12_RS10195 764972c0c90d5f6a9b9be0e12484d121 681 Pfam PF02120 Flagellar hook-length control protein FliK 551 634 3.2E-25 T 28-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal A6A12_RS08960 819bed271829c4215d819ab28652542f 221 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 34 204 1.3E-6 T 28-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 A6A12_RS04030 3f98e0cce30254a98012f1ccf93fb48d 99 Pfam PF11743 Protein of unknown function (DUF3301) 6 96 2.3E-27 T 28-03-2018 IPR021732 Protein of unknown function DUF3301 A6A12_RS07550 db10075348a8d2fd89dd6f301907ed09 235 Pfam PF01618 MotA/TolQ/ExbB proton channel family 96 194 4.1E-22 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 A6A12_RS05860 4200ceb530c0585a50a377308316fc33 147 Pfam PF05232 Chlorhexidine efflux transporter 8 69 8.8E-24 T 28-03-2018 IPR007896 Chlorhexidine efflux transporter A6A12_RS05860 4200ceb530c0585a50a377308316fc33 147 Pfam PF05232 Chlorhexidine efflux transporter 75 137 2.7E-24 T 28-03-2018 IPR007896 Chlorhexidine efflux transporter A6A12_RS05510 b84e1c3cecd0b880be9822330071cbc3 107 Pfam PF11872 Protein of unknown function (DUF3392) 2 104 4.4E-40 T 28-03-2018 IPR021813 Protein of unknown function DUF3392 A6A12_RS13890 88aba691fed126304243d3f3d416d7ca 141 Gene3D G3DSA:1.20.1070.10 2 124 6.9E-4 T 28-03-2018 A6A12_RS07505 8a208e6c333c25127e92f2a3cd55f798 345 Pfam PF09375 Imelysin 44 323 6.4E-36 T 28-03-2018 IPR018976 Peptidase M75, Imelysin A6A12_RS11495 c917087d7f0ca5b53a4ed673cabbbe02 151 Pfam PF05258 Protein of unknown function (DUF721) 12 89 5.1E-11 T 28-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 A6A12_RS13755 199a94eaf3523b044f22065fa38d4442 100 Pfam PF12305 Protein of unknown function (DUF3630) 5 96 8.6E-39 T 28-03-2018 IPR022080 Protein of unknown function DUF3630