locus-tag	class	description
CEG15_RS00005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEG15_RS00015	COG0706	membrane insertase activity
CEG15_RS00035	COG1126	abc transporter atp-binding protein
CEG15_RS00055	COG0592	DNA-directed DNA polymerase activity
CEG15_RS00060	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEG15_RS00065	COG0187	DNA topoisomerase II activity
CEG15_RS00080	COG0071	Belongs to the small heat shock protein (HSP20) family
CEG15_RS00085	COG3977	Valine--pyruvate aminotransferase
CEG15_RS00095	COG0752	glycyl-tRNA synthetase alpha subunit
CEG15_RS00100	COG2119	membrane
CEG15_RS00110	COG0425	Belongs to the sulfur carrier protein TusA family
CEG15_RS00125	COG0604	alcohol dehydrogenase
CEG15_RS00140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEG15_RS00145	COG3978	acetolactate synthase activity
CEG15_RS00155	COG0606	chelatase, subunit chli
CEG15_RS00165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEG15_RS00170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CEG15_RS00185	COG3084	Protein conserved in bacteria
CEG15_RS00195	COG1272	protein, Hemolysin III
CEG15_RS00205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEG15_RS00210	COG0569	domain protein
CEG15_RS00215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEG15_RS00215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEG15_RS00220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEG15_RS00225	COG0242	peptide deformylase activity
CEG15_RS00230	COG1652	LysM domain
CEG15_RS00235	COG0758	DNA mediated transformation
CEG15_RS00240	COG2922	Belongs to the Smg family
CEG15_RS00245	COG0551	DNA topoisomerase type I activity
CEG15_RS00255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CEG15_RS00260	COG0009	L-threonylcarbamoyladenylate synthase
CEG15_RS00265	COG0408	coproporphyrinogen oxidase activity
CEG15_RS00270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEG15_RS00280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CEG15_RS00315	COG3071	HemY protein
CEG15_RS00320	COG2959	enzyme of heme biosynthesis
CEG15_RS00325	COG1587	Uroporphyrinogen-III synthase
CEG15_RS00350	COG0019	diaminopimelate decarboxylase activity
CEG15_RS00355	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CEG15_RS00365	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CEG15_RS00370	COG1011	Hydrolase
CEG15_RS00375	COG3148	PFAM DTW domain containing protein
CEG15_RS00385	COG0561	phosphatase activity
CEG15_RS00390	COG2267	carboxylic ester hydrolase activity
CEG15_RS00395	COG1280	lysine exporter protein (LysE YggA)
CEG15_RS00400	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CEG15_RS00405	COG0783	Belongs to the Dps family
CEG15_RS00445	COG2095	MarC family integral membrane protein
CEG15_RS00455	COG0742	ribosomal rna small subunit methyltransferase
CEG15_RS00460	COG0552	protein localization to endoplasmic reticulum
CEG15_RS00465	COG2884	Cell division ATP-binding protein ftsE
CEG15_RS00470	COG2177	Part of the ABC transporter FtsEX involved in
CEG15_RS00475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEG15_RS00485	COG0705	Rhomboid family
CEG15_RS00490	COG1580	Controls the rotational direction of flagella during chemotaxis
CEG15_RS00495	COG3161	chorismate lyase activity
CEG15_RS00505	COG2937	Belongs to the GPAT DAPAT family
CEG15_RS00510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CEG15_RS00520	COG0534	Mate efflux family protein
CEG15_RS00525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEG15_RS00540	COG3250	beta-galactosidase activity
CEG15_RS00570	COG0732	type I restriction modification DNA specificity domain
CEG15_RS00590	COG2003	Belongs to the UPF0758 family
CEG15_RS00640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEG15_RS00715	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CEG15_RS00720	COG5001	Diguanylate cyclase
CEG15_RS00720	COG3300	MHYT domain
CEG15_RS00730	COG3852	Histidine kinase
CEG15_RS00740	COG0174	glutamine synthetase
CEG15_RS00745	COG1217	gtp-binding protein TYPA
CEG15_RS00750	COG1295	ribonuclease BN
CEG15_RS00755	COG1490	D-aminoacyl-tRNA deacylase activity
CEG15_RS00760	COG0456	acetyltransferase
CEG15_RS00770	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CEG15_RS00775	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEG15_RS00780	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEG15_RS00785	COG3031	protein transport across the cell outer membrane
CEG15_RS00795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEG15_RS00800	COG1459	type II secretion system
CEG15_RS00805	COG2165	general secretion pathway protein
CEG15_RS00810	COG2165	general secretion pathway protein
CEG15_RS00815	COG2165	general secretion pathway protein
CEG15_RS00820	COG4795	General secretion pathway protein
CEG15_RS00825	COG3156	type II secretion system protein K
CEG15_RS00830	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CEG15_RS00835	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CEG15_RS00845	COG1218	3'(2'),5'-bisphosphate nucleotidase
CEG15_RS00850	COG0494	nUDIX hydrolase
CEG15_RS00855	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CEG15_RS00855	COG0316	Belongs to the HesB IscA family
CEG15_RS00860	COG1040	competence protein
CEG15_RS00865	COG0596	Alpha beta hydrolase
CEG15_RS00875	COG2183	response to ionizing radiation
CEG15_RS00880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEG15_RS00900	COG0583	DNA-binding transcription factor activity
CEG15_RS00910	COG0778	Nitroreductase
CEG15_RS00930	COG2233	PERMEase
CEG15_RS00935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEG15_RS00940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEG15_RS00945	COG1758	RNA polymerase activity
CEG15_RS00950	COG0194	GDP metabolic process
CEG15_RS00955	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CEG15_RS00960	COG0248	Ppx GppA phosphatase
CEG15_RS00970	COG3118	belongs to the thioredoxin family
CEG15_RS00985	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CEG15_RS01045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEG15_RS01055	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEG15_RS01060	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CEG15_RS01060	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CEG15_RS01065	COG1072	(Pantothenic acid kinase))
CEG15_RS01090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEG15_RS01095	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEG15_RS01100	COG0250	Participates in transcription elongation, termination and antitermination
CEG15_RS01115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEG15_RS01120	COG0222	ribosome binding
CEG15_RS01125	COG0085	RNA polymerase activity
CEG15_RS01130	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEG15_RS01135	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CEG15_RS01140	COG2816	NAD+ diphosphatase activity
CEG15_RS01145	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CEG15_RS01160	COG4942	peptidase
CEG15_RS01165	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CEG15_RS01180	COG0471	metal ion transport
CEG15_RS01180	COG0490	domain, Protein
CEG15_RS01190	COG1162	GTPase activity
CEG15_RS01195	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CEG15_RS01240	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEG15_RS01245	COG0802	atpase or kinase
CEG15_RS01255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEG15_RS01260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CEG15_RS01270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEG15_RS01275	COG0330	HflC and HflK could
CEG15_RS01280	COG0330	HflC and HflK could
CEG15_RS01285	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CEG15_RS01300	COG0545	Peptidyl-prolyl cis-trans isomerase
CEG15_RS01305	COG2964	Protein conserved in bacteria
CEG15_RS01310	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CEG15_RS01315	COG2923	Belongs to the DsrF TusC family
CEG15_RS01330	COG0049	tRNA binding
CEG15_RS01335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEG15_RS01340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEG15_RS01345	COG0360	Binds together with S18 to 16S ribosomal RNA
CEG15_RS01350	COG2965	DNA replication, synthesis of RNA primer
CEG15_RS01360	COG0359	binds to the 23S rRNA
CEG15_RS01375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEG15_RS01380	COG0166	Belongs to the GPI family
CEG15_RS01390	COG0735	belongs to the Fur family
CEG15_RS01395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEG15_RS01415	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CEG15_RS01425	COG0175	sulfate reduction
CEG15_RS01510	COG0646	methionine synthase
CEG15_RS01510	COG1410	methionine synthase
CEG15_RS01515	COG0527	aspartate kinase activity
CEG15_RS01520	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CEG15_RS01535	COG2239	Acts as a magnesium transporter
CEG15_RS01545	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEG15_RS01560	COG0629	single-stranded DNA binding
CEG15_RS01565	COG2199	diguanylate cyclase activity
CEG15_RS01565	COG2200	EAL domain
CEG15_RS01590	COG3267	Type II secretory pathway component ExeA
CEG15_RS01590	COG3409	Peptidoglycan-binding domain 1 protein
CEG15_RS01600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEG15_RS01605	COG1459	type II secretion system
CEG15_RS01615	COG2165	general secretion pathway protein
CEG15_RS01650	COG1077	Cell shape determining protein MreB Mrl
CEG15_RS01655	COG1792	Involved in formation and maintenance of cell shape
CEG15_RS01660	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CEG15_RS01665	COG0424	maF-like protein
CEG15_RS01675	COG3164	Protein of unknown function
CEG15_RS01680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEG15_RS01685	COG0312	modulator of DNA gyrase
CEG15_RS01690	COG2235	arginine
CEG15_RS01710	COG0589	response to stress
CEG15_RS01720	COG2358	TRAP transporter, solute receptor (TAXI family
CEG15_RS01730	COG1438	arginine binding
CEG15_RS01740	COG0531	amino acid
CEG15_RS01745	COG0142	geranyltranstransferase activity
CEG15_RS01755	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CEG15_RS01760	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEG15_RS01765	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEG15_RS01770	COG2966	Psort location CytoplasmicMembrane, score
CEG15_RS01775	COG3610	response to peptide
CEG15_RS01790	COG2967	ApaG domain
CEG15_RS01795	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CEG15_RS01800	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CEG15_RS01805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEG15_RS01810	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CEG15_RS01815	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CEG15_RS01865	COG0741	lytic transglycosylase activity
CEG15_RS01870	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CEG15_RS01905	COG2313	pseudouridylate synthase activity
CEG15_RS01915	COG1846	Transcriptional regulator
CEG15_RS01920	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEG15_RS01925	COG0697	spore germination
CEG15_RS01935	COG1942	4-Oxalocrotonate Tautomerase
CEG15_RS01940	COG0546	phosphoglycolate phosphatase activity
CEG15_RS01950	COG1194	a g-specific adenine glycosylase
CEG15_RS01960	COG2066	Belongs to the glutaminase family
CEG15_RS01965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEG15_RS01970	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CEG15_RS01980	COG1872	DUF167
CEG15_RS01985	COG0762	integral membrane protein
CEG15_RS01990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CEG15_RS01995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CEG15_RS02010	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CEG15_RS02015	COG1678	Uncharacterized ACR, COG1678
CEG15_RS02025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEG15_RS02030	COG2356	endonuclease I
CEG15_RS02035	COG3091	SprT-like family
CEG15_RS02040	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEG15_RS02045	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEG15_RS02050	COG0583	DNA-binding transcription factor activity
CEG15_RS02055	COG4771	TonB-dependent receptor
CEG15_RS02060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEG15_RS02065	COG0126	phosphoglycerate kinase activity
CEG15_RS02075	COG0191	fructose-bisphosphate aldolase activity
CEG15_RS02080	COG0668	transmembrane transport
CEG15_RS02115	COG1349	DNA-binding transcription factor activity
CEG15_RS02140	COG3501	Rhs element vgr protein
CEG15_RS02145	COG4104	PAAR repeat-containing protein
CEG15_RS02185	COG0358	DNA primase activity
CEG15_RS02190	COG1610	YqeY-like protein
CEG15_RS02195	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CEG15_RS02200	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CEG15_RS02210	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CEG15_RS02215	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CEG15_RS02220	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEG15_RS02225	COG1968	undecaprenyl-diphosphatase activity
CEG15_RS02230	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CEG15_RS02235	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CEG15_RS02240	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CEG15_RS02245	COG0585	pseudouridine synthase activity
CEG15_RS02250	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CEG15_RS02255	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CEG15_RS02260	COG1388	LysM domain
CEG15_RS02260	COG4942	peptidase
CEG15_RS02265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEG15_RS02270	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEG15_RS02290	COG4208	sulfate ABC transporter
CEG15_RS02295	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CEG15_RS02300	COG1546	Belongs to the CinA family
CEG15_RS02305	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEG15_RS02310	COG2137	regulation of response to DNA damage stimulus
CEG15_RS02315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEG15_RS02320	COG0527	aspartate kinase activity
CEG15_RS02325	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CEG15_RS02370	COG3630	sodium ion export across plasma membrane
CEG15_RS02375	COG5016	pyruvate
CEG15_RS02375	COG0511	ligase activity, forming carbon-carbon bonds
CEG15_RS02380	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CEG15_RS02390	COG1238	metal cluster binding
CEG15_RS02395	COG0612	Peptidase, M16
CEG15_RS02405	COG1854	S-ribosylhomocysteine lyase activity
CEG15_RS02410	COG4536	flavin adenine dinucleotide binding
CEG15_RS02415	COG4137	Cytochrome C assembly protein
CEG15_RS02420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEG15_RS02425	COG0228	four-way junction DNA binding
CEG15_RS02430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CEG15_RS02435	COG0336	Belongs to the RNA methyltransferase TrmD family
CEG15_RS02440	COG0335	large ribosomal subunit rRNA binding
CEG15_RS02450	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CEG15_RS02455	COG0237	dephospho-CoA kinase activity
CEG15_RS02465	COG1459	type II secretion system
CEG15_RS02470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEG15_RS02480	COG0157	Belongs to the NadC ModD family
CEG15_RS02490	COG0716	FMN binding
CEG15_RS02495	COG4974	Belongs to the 'phage' integrase family
CEG15_RS02500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEG15_RS02505	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CEG15_RS02510	COG2186	Transcriptional regulator
CEG15_RS02515	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CEG15_RS02520	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEG15_RS02525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEG15_RS02540	COG0288	reversible hydration of carbon dioxide
CEG15_RS02545	COG0659	secondary active sulfate transmembrane transporter activity
CEG15_RS02550	COG1131	(ABC) transporter
CEG15_RS02555	COG0842	Transport permease protein
CEG15_RS02570	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CEG15_RS02580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEG15_RS02590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEG15_RS02595	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CEG15_RS02600	COG1489	DNA binding
CEG15_RS02605	COG1643	Atp-dependent helicase
CEG15_RS02610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEG15_RS02615	COG1752	Esterase of the alpha-beta hydrolase superfamily
CEG15_RS02620	COG1049	propionate catabolic process, 2-methylcitrate cycle
CEG15_RS02625	COG1929	Belongs to the glycerate kinase type-1 family
CEG15_RS02630	COG2610	gluconate transmembrane transporter activity
CEG15_RS02635	COG3835	regulator
CEG15_RS02640	COG3112	Uncharacterised protein family (UPF0231)
CEG15_RS02650	COG0004	ammonium transporteR
CEG15_RS02655	COG1840	ABC-type Fe3 transport system, periplasmic component
CEG15_RS02665	COG3842	ATPase activity
CEG15_RS02670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEG15_RS02685	COG2971	BadF BadG BcrA BcrD
CEG15_RS02695	COG4608	Belongs to the ABC transporter superfamily
CEG15_RS02700	COG0444	Belongs to the ABC transporter superfamily
CEG15_RS02705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEG15_RS02720	COG0784	Response regulator, receiver
CEG15_RS02720	COG2205	protein histidine kinase activity
CEG15_RS02730	COG0628	permease
CEG15_RS02735	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEG15_RS02740	COG0316	Belongs to the HesB IscA family
CEG15_RS02755	COG0739	heme binding
CEG15_RS02760	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEG15_RS02770	COG2239	Acts as a magnesium transporter
CEG15_RS02775	COG2027	D-alanyl-D-alanine carboxypeptidase
CEG15_RS02785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEG15_RS02790	COG1534	Rna-binding protein
CEG15_RS02795	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CEG15_RS02800	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEG15_RS02805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CEG15_RS02810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEG15_RS02815	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEG15_RS02830	COG0779	Required for maturation of 30S ribosomal subunits
CEG15_RS02835	COG0195	Participates in both transcription termination and antitermination
CEG15_RS02850	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CEG15_RS02855	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CEG15_RS02870	COG1846	Transcriptional regulator
CEG15_RS02880	COG0826	peptidase U32
CEG15_RS02885	COG0826	peptidase U32
CEG15_RS02895	COG3154	lipid carrier protein
CEG15_RS02900	COG3153	acetyltransferase
CEG15_RS02925	COG0513	Belongs to the DEAD box helicase family
CEG15_RS02930	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CEG15_RS02945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CEG15_RS02950	COG2204	response regulator
CEG15_RS02960	COG0667	Aldo Keto reductase
CEG15_RS02970	COG0494	nUDIX hydrolase
CEG15_RS02975	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CEG15_RS02980	COG0730	response to heat
CEG15_RS02990	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEG15_RS03015	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEG15_RS03050	COG1132	(ABC) transporter
CEG15_RS03080	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEG15_RS03085	COG1283	sodium-dependent phosphate transmembrane transporter activity
CEG15_RS03090	COG0583	DNA-binding transcription factor activity
CEG15_RS03095	COG0640	Transcriptional regulator
CEG15_RS03100	COG0268	Binds directly to 16S ribosomal RNA
CEG15_RS03105	COG0728	peptidoglycan biosynthetic process
CEG15_RS03110	COG0196	riboflavin kinase activity
CEG15_RS03120	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CEG15_RS03125	COG1047	Peptidyl-prolyl cis-trans
CEG15_RS03130	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CEG15_RS03135	COG1966	Carbon starvation protein
CEG15_RS03145	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEG15_RS03150	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CEG15_RS03160	COG3279	Response regulator of the LytR AlgR family
CEG15_RS03165	COG3275	phosphorelay sensor kinase activity
CEG15_RS03170	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEG15_RS03175	COG1605	Chorismate mutase
CEG15_RS03175	COG0287	Prephenate dehydrogenase
CEG15_RS03185	COG0488	(ABC) transporter
CEG15_RS03195	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CEG15_RS03200	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CEG15_RS03205	COG5001	Diguanylate cyclase
CEG15_RS03210	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEG15_RS03215	COG1605	Chorismate mutase
CEG15_RS03215	COG0077	Prephenate dehydratase
CEG15_RS03220	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEG15_RS03225	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEG15_RS03230	COG0564	pseudouridine synthase activity
CEG15_RS03235	COG1496	oxidoreductase activity
CEG15_RS03240	COG0542	response to heat
CEG15_RS03285	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEG15_RS03290	COG0826	peptidase U32
CEG15_RS03300	COG0745	RESPONSE REGULATOR receiver
CEG15_RS03305	COG5002	protein histidine kinase activity
CEG15_RS03315	COG0248	Ppx GppA phosphatase
CEG15_RS03320	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CEG15_RS03330	COG0581	inorganic phosphate transmembrane transporter activity
CEG15_RS03335	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEG15_RS03340	COG0704	Plays a role in the regulation of phosphate uptake
CEG15_RS03350	COG0450	alkyl hydroperoxide reductase
CEG15_RS03355	COG0583	DNA-binding transcription factor activity
CEG15_RS03360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CEG15_RS03370	COG0517	IMP dehydrogenase activity
CEG15_RS03380	COG0343	queuine tRNA-ribosyltransferase activity
CEG15_RS03385	COG1862	Preprotein translocase
CEG15_RS03390	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEG15_RS03395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEG15_RS03400	COG0483	inositol monophosphate 1-phosphatase activity
CEG15_RS03405	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CEG15_RS03410	COG1959	2 iron, 2 sulfur cluster binding
CEG15_RS03420	COG0822	iron-sulfur transferase activity
CEG15_RS03425	COG0316	Belongs to the HesB IscA family
CEG15_RS03435	COG0443	Heat shock 70 kDa protein
CEG15_RS03440	COG0633	Ferredoxin
CEG15_RS03445	COG2975	iron-sulfur cluster assembly
CEG15_RS03450	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEG15_RS03470	COG1426	Protein conserved in bacteria
CEG15_RS03475	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CEG15_RS03480	COG0124	histidyl-tRNA synthetase
CEG15_RS03485	COG2976	Protein conserved in bacteria
CEG15_RS03490	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEG15_RS03495	COG1160	GTP binding
CEG15_RS03510	COG0516	GMP reductase activity
CEG15_RS03510	COG0517	IMP dehydrogenase activity
CEG15_RS03515	COG0519	Catalyzes the synthesis of GMP from XMP
CEG15_RS03515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEG15_RS03520	COG0351	phosphomethylpyrimidine kinase
CEG15_RS03530	COG1584	GPR1 FUN34 yaaH family protein
CEG15_RS03535	COG1115	amino acid carrier protein
CEG15_RS03560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_RS03560	COG3711	transcriptional antiterminator
CEG15_RS03575	COG3964	amidohydrolase
CEG15_RS03660	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CEG15_RS03665	COG4804	nuclease activity
CEG15_RS03670	COG0732	type I restriction modification DNA specificity domain
CEG15_RS03680	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CEG15_RS03700	COG2867	negative regulation of translational initiation
CEG15_RS03705	COG2914	Belongs to the UPF0125 (RnfH) family
CEG15_RS03710	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEG15_RS03715	COG0497	DNA recombination
CEG15_RS03720	COG0251	oxidation-reduction process
CEG15_RS03725	COG0814	amino acid
CEG15_RS03730	COG3033	Beta-eliminating lyase
CEG15_RS03735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEG15_RS03740	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEG15_RS03745	COG0443	Heat shock 70 kDa protein
CEG15_RS03750	COG0484	heat shock protein binding
CEG15_RS03780	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CEG15_RS03785	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CEG15_RS03795	COG0583	DNA-binding transcription factor activity
CEG15_RS03800	COG0590	tRNA wobble adenosine to inosine editing
CEG15_RS03805	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CEG15_RS03815	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEG15_RS03815	COG0047	phosphoribosylformylglycinamidine synthase activity
CEG15_RS03835	COG2979	Protein of unknown function (DUF533)
CEG15_RS03840	COG0442	prolyl-tRNA aminoacylation
CEG15_RS03845	COG1720	tRNA m6t6A37 methyltransferase activity
CEG15_RS03850	COG0254	rRNA binding
CEG15_RS03855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEG15_RS03885	COG3098	single-species biofilm formation
CEG15_RS03890	COG0564	pseudouridine synthase activity
CEG15_RS03895	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEG15_RS03900	COG0142	geranyltranstransferase activity
CEG15_RS03905	COG1722	exodeoxyribonuclease VII activity
CEG15_RS03910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CEG15_RS03920	COG0301	tRNA thio-modification
CEG15_RS03920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEG15_RS03925	COG0583	DNA-binding transcription factor activity
CEG15_RS03930	COG2363	Small membrane protein
CEG15_RS03935	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CEG15_RS03940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEG15_RS03945	COG1611	Belongs to the LOG family
CEG15_RS03970	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CEG15_RS03975	COG1464	Belongs to the NlpA lipoprotein family
CEG15_RS03980	COG2011	ABC-type metal ion transport system permease component
CEG15_RS03985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CEG15_RS03990	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEG15_RS04005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEG15_RS04005	COG1263	PTS System
CEG15_RS04010	COG0366	Alpha amylase catalytic
CEG15_RS04015	COG0745	RESPONSE REGULATOR receiver
CEG15_RS04020	COG2205	protein histidine kinase activity
CEG15_RS04055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEG15_RS04060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEG15_RS04075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEG15_RS04080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CEG15_RS04085	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CEG15_RS04125	COG1045	serine acetyltransferase
CEG15_RS04135	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CEG15_RS04165	COG0489	protein tyrosine kinase activity
CEG15_RS04170	COG1596	polysaccharide export
CEG15_RS04200	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CEG15_RS04205	COG0321	lipoyl(octanoyl) transferase activity
CEG15_RS04210	COG2921	Belongs to the UPF0250 family
CEG15_RS04215	COG1686	Belongs to the peptidase S11 family
CEG15_RS04220	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CEG15_RS04225	COG0772	Belongs to the SEDS family
CEG15_RS04230	COG0768	penicillin binding
CEG15_RS04235	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEG15_RS04240	COG0799	negative regulation of ribosome biogenesis
CEG15_RS04245	COG1466	dna polymerase III delta subunit
CEG15_RS04250	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CEG15_RS04255	COG0495	leucyl-tRNA aminoacylation
CEG15_RS04260	COG2888	peptidyl-tyrosine sulfation
CEG15_RS04265	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CEG15_RS04270	COG4535	Mg2 and Co2 transporter CorC
CEG15_RS04275	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CEG15_RS04280	COG1702	phosphate starvation-inducible protein PhoH
CEG15_RS04285	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEG15_RS04290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEG15_RS04295	COG2190	(PTS) system
CEG15_RS04300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEG15_RS04305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_RS04310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEG15_RS04315	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CEG15_RS04320	COG3115	cell septum assembly
CEG15_RS04325	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEG15_RS04340	COG0789	Transcriptional regulator
CEG15_RS04350	COG0330	HflC and HflK could
CEG15_RS04355	COG3118	belongs to the thioredoxin family
CEG15_RS04360	COG1090	epimerase
CEG15_RS04365	COG0622	Phosphoesterase
CEG15_RS04380	COG3710	Transcriptional regulator
CEG15_RS04385	COG0326	Molecular chaperone. Has ATPase activity
CEG15_RS04395	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEG15_RS04400	COG3104	oligopeptide transport
CEG15_RS04410	COG0367	asparagine synthase
CEG15_RS04415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEG15_RS04415	COG4651	solute:proton antiporter activity
CEG15_RS04420	COG1846	Transcriptional regulator
CEG15_RS04420	COG1940	carbohydrate kinase activity
CEG15_RS04425	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEG15_RS04430	COG2190	(PTS) system
CEG15_RS04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEG15_RS04430	COG1263	PTS System
CEG15_RS04435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEG15_RS04445	COG0101	tRNA pseudouridine synthase activity
CEG15_RS04450	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CEG15_RS04455	COG0285	dihydrofolate synthase activity
CEG15_RS04460	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CEG15_RS04465	COG1286	toxin biosynthetic process
CEG15_RS04470	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CEG15_RS04475	COG2056	Na+-H+ antiporter family
CEG15_RS04480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEG15_RS04490	COG0346	lactoylglutathione lyase activity
CEG15_RS04495	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEG15_RS04500	COG4660	Part of a membrane complex involved in electron transport
CEG15_RS04505	COG4659	FMN binding
CEG15_RS04510	COG4658	electron transport chain
CEG15_RS04515	COG4656	Part of a membrane complex involved in electron transport
CEG15_RS04520	COG2878	Part of a membrane complex involved in electron transport
CEG15_RS04525	COG4657	Part of a membrane complex involved in electron transport
CEG15_RS04535	COG1629	transport
CEG15_RS04535	COG4774	siderophore transport
CEG15_RS04540	COG2382	esterase
CEG15_RS04560	COG3433	isochorismatase activity
CEG15_RS04560	COG1535	isochorismatase
CEG15_RS04565	COG1021	2,3-dihydroxybenzoate-AMP ligase
CEG15_RS04570	COG1169	isochorismate synthase
CEG15_RS04575	COG1028	Short-chain dehydrogenase reductase Sdr
CEG15_RS04580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEG15_RS04585	COG1902	pentaerythritol trinitrate reductase activity
CEG15_RS04595	COG2814	Major facilitator Superfamily
CEG15_RS04600	COG1028	Short-chain dehydrogenase reductase Sdr
CEG15_RS04615	COG0556	nucleotide-excision repair
CEG15_RS04620	COG2204	response regulator
CEG15_RS04625	COG2198	Histidine kinase
CEG15_RS04630	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CEG15_RS04635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEG15_RS04640	COG0521	Mo-molybdopterin cofactor biosynthetic process
CEG15_RS04650	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CEG15_RS04655	COG0314	molybdopterin synthase activity
CEG15_RS04660	COG2199	diguanylate cyclase activity
CEG15_RS04665	COG0617	tRNA 3'-terminal CCA addition
CEG15_RS04665	COG0517	IMP dehydrogenase activity
CEG15_RS04665	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CEG15_RS04675	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CEG15_RS04685	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEG15_RS04685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEG15_RS04690	COG0489	protein tyrosine kinase activity
CEG15_RS04695	COG0572	uridine kinase
CEG15_RS04700	COG2982	Protein involved in outer membrane biogenesis
CEG15_RS04705	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CEG15_RS04710	COG2067	long-chain fatty acid transport protein
CEG15_RS04725	COG1595	DNA-templated transcription, initiation
CEG15_RS04735	COG0183	Belongs to the thiolase family
CEG15_RS04740	COG1024	Enoyl-CoA hydratase
CEG15_RS04740	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEG15_RS04745	COG0778	Nitroreductase
CEG15_RS04750	COG0583	DNA-binding transcription factor activity
CEG15_RS04755	COG0745	RESPONSE REGULATOR receiver
CEG15_RS04765	COG2832	Protein of unknown function (DUF454)
CEG15_RS04770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEG15_RS04785	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CEG15_RS04795	COG2983	Belongs to the UPF0260 family
CEG15_RS04810	COG2226	methyltransferase
CEG15_RS04825	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEG15_RS04835	COG3139	Protein of unknown function (DUF1315)
CEG15_RS04840	COG0252	asparaginase activity
CEG15_RS04845	COG0616	signal peptide processing
CEG15_RS04850	COG1902	pentaerythritol trinitrate reductase activity
CEG15_RS04850	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEG15_RS04855	COG0788	formyltetrahydrofolate deformylase activity
CEG15_RS04865	COG1199	ATP-dependent helicase activity
CEG15_RS04870	COG1214	PFAM Peptidase M22, glycoprotease
CEG15_RS04885	COG0596	Alpha beta hydrolase
CEG15_RS04890	COG0318	PFAM AMP-dependent synthetase and ligase
CEG15_RS04895	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CEG15_RS04900	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CEG15_RS04905	COG2894	cell division
CEG15_RS04915	COG3100	YcgL domain-containing protein
CEG15_RS04920	COG2951	lytic endotransglycosylase activity
CEG15_RS04925	COG0583	DNA-binding transcription factor activity
CEG15_RS04930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEG15_RS04955	COG4628	conserved protein (DUF2132)
CEG15_RS04970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEG15_RS04980	COG0513	Belongs to the DEAD box helicase family
CEG15_RS04990	COG1760	l-serine dehydratase
CEG15_RS04995	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CEG15_RS05005	COG2205	protein histidine kinase activity
CEG15_RS05010	COG1653	transport
CEG15_RS05020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEG15_RS05025	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CEG15_RS05030	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEG15_RS05050	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEG15_RS05060	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CEG15_RS05065	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CEG15_RS05070	COG0776	regulation of translation
CEG15_RS05075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEG15_RS05080	COG1555	photosystem II stabilization
CEG15_RS05085	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CEG15_RS05090	COG0539	negative regulation of cytoplasmic translation
CEG15_RS05095	COG0776	regulation of translation
CEG15_RS05100	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CEG15_RS05105	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CEG15_RS05120	COG0583	DNA-binding transcription factor activity
CEG15_RS05130	COG0686	Belongs to the AlaDH PNT family
CEG15_RS05135	COG1522	sequence-specific DNA binding
CEG15_RS05150	COG0501	Belongs to the peptidase M48B family
CEG15_RS05160	COG0300	oxidoreductase activity
CEG15_RS05175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEG15_RS05185	COG2268	Band 7 protein
CEG15_RS05195	COG1032	radical SAM domain protein
CEG15_RS05220	COG0583	DNA-binding transcription factor activity
CEG15_RS05225	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEG15_RS05235	COG2350	Protein conserved in bacteria
CEG15_RS05265	COG0159	tryptophan synthase activity
CEG15_RS05270	COG0133	tryptophan synthase activity
CEG15_RS05275	COG0135	phosphoribosylanthranilate isomerase activity
CEG15_RS05275	COG0134	indole-3-glycerol-phosphate synthase activity
CEG15_RS05280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEG15_RS05285	COG0512	Glutamine amidotransferase of anthranilate synthase
CEG15_RS05290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CEG15_RS05300	COG0613	PHP domain protein
CEG15_RS05305	COG0009	L-threonylcarbamoyladenylate synthase
CEG15_RS05310	COG1187	pseudouridine synthase activity
CEG15_RS05320	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CEG15_RS05325	COG4988	ABC transporter
CEG15_RS05330	COG0492	ferredoxin-NADP+ reductase activity
CEG15_RS05350	COG2949	membrane
CEG15_RS05360	COG0281	malic enzyme
CEG15_RS05370	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CEG15_RS05375	COG2985	domain, Protein
CEG15_RS05375	COG3273	potassium ion transport
CEG15_RS05380	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEG15_RS05390	COG1737	Transcriptional regulator
CEG15_RS05395	COG0076	glutamate decarboxylase activity
CEG15_RS05405	COG2431	L-lysine efflux transmembrane transporter activity
CEG15_RS05415	COG3070	regulator of competence-specific genes
CEG15_RS05430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEG15_RS05430	COG4191	Histidine kinase
CEG15_RS05440	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CEG15_RS05445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CEG15_RS05450	COG2915	High frequency lysogenization protein hflD homolog
CEG15_RS05455	COG0482	sulfurtransferase activity
CEG15_RS05465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEG15_RS05470	COG2916	Histone family protein nucleoid-structuring protein H-NS
CEG15_RS05475	COG1757	Na H antiporter
CEG15_RS05480	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CEG15_RS05485	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEG15_RS05490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEG15_RS05495	COG0131	Imidazoleglycerol-phosphate dehydratase
CEG15_RS05495	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEG15_RS05500	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEG15_RS05510	COG0107	imidazoleglycerol-phosphate synthase activity
CEG15_RS05515	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CEG15_RS05515	COG0140	phosphoribosyl-ATP diphosphatase activity
CEG15_RS05520	COG1187	pseudouridine synthase activity
CEG15_RS05530	COG1278	Cold shock
CEG15_RS05535	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CEG15_RS05540	COG0542	response to heat
CEG15_RS05545	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CEG15_RS05550	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CEG15_RS05555	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CEG15_RS05570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEG15_RS05575	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEG15_RS05580	COG0297	glycogen (starch) synthase activity
CEG15_RS05600	COG3070	regulator of competence-specific genes
CEG15_RS05605	COG1609	Transcriptional regulator
CEG15_RS05615	COG0745	RESPONSE REGULATOR receiver
CEG15_RS05620	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CEG15_RS05625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEG15_RS05635	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CEG15_RS05640	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CEG15_RS05655	COG0189	ligase activity
CEG15_RS05655	COG4067	protein conserved in archaea
CEG15_RS05660	COG0500	methyltransferase
CEG15_RS05670	COG1801	Protein of unknown function DUF72
CEG15_RS05675	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEG15_RS05680	COG1435	thymidine kinase activity
CEG15_RS05690	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CEG15_RS05715	COG2116	formate transmembrane transporter activity
CEG15_RS05720	COG4459	periplasmic nitrate reductase
CEG15_RS05725	COG3005	denitrification pathway
CEG15_RS05730	COG0243	molybdopterin cofactor binding
CEG15_RS05740	COG1227	inorganic diphosphatase activity
CEG15_RS05760	COG3344	reverse transcriptase
CEG15_RS05770	COG4172	Belongs to the ABC transporter superfamily
CEG15_RS05780	COG4171	peptide transport system, permease
CEG15_RS05795	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CEG15_RS05800	COG1842	Phage shock protein A
CEG15_RS05815	COG0519	Catalyzes the synthesis of GMP from XMP
CEG15_RS05820	COG0626	cystathionine gamma-synthase activity
CEG15_RS05830	COG0733	neurotransmitter:sodium symporter activity
CEG15_RS05835	COG0564	pseudouridine synthase activity
CEG15_RS05845	COG2200	EAL domain
CEG15_RS05850	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEG15_RS05855	COG4136	ATPase activity
CEG15_RS05860	COG4135	transport system, permease component
CEG15_RS05865	COG4134	Bacterial extracellular solute-binding protein
CEG15_RS05875	COG3313	Fe-S protein
CEG15_RS05885	COG0737	Belongs to the 5'-nucleotidase family
CEG15_RS05895	COG0513	Belongs to the DEAD box helicase family
CEG15_RS05910	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CEG15_RS05915	COG2205	protein histidine kinase activity
CEG15_RS05930	COG1061	Type III restriction enzyme res subunit
CEG15_RS05935	COG1187	pseudouridine synthase activity
CEG15_RS05940	COG2814	Major facilitator Superfamily
CEG15_RS05950	COG0702	epimerase
CEG15_RS05955	COG0534	Mate efflux family protein
CEG15_RS05960	COG4181	ATPase activity
CEG15_RS05975	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CEG15_RS06030	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEG15_RS06035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEG15_RS06040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEG15_RS06050	COG0840	transmembrane signaling receptor activity
CEG15_RS06065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEG15_RS06065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEG15_RS06065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_RS06070	COG2207	Transcriptional regulator
CEG15_RS06080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEG15_RS06090	COG1342	Belongs to the UPF0251 family
CEG15_RS06110	COG1129	ABC transporter
CEG15_RS06120	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEG15_RS06125	COG5002	protein histidine kinase activity
CEG15_RS06130	COG0745	RESPONSE REGULATOR receiver
CEG15_RS06160	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CEG15_RS06165	COG0372	Belongs to the citrate synthase family
CEG15_RS06170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CEG15_RS06175	COG2828	Protein conserved in bacteria
CEG15_RS06195	COG0561	phosphatase activity
CEG15_RS06200	COG0602	queuosine metabolic process
CEG15_RS06245	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEG15_RS06250	COG1254	Belongs to the acylphosphatase family
CEG15_RS06255	COG2920	part of a sulfur-relay system
CEG15_RS06260	COG0670	Belongs to the BI1 family
CEG15_RS06265	COG1126	abc transporter atp-binding protein
CEG15_RS06270	COG0765	amino acid transport
CEG15_RS06275	COG4597	amino acid ABC transporter
CEG15_RS06280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEG15_RS06285	COG1648	precorrin-2 dehydrogenase activity
CEG15_RS06285	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEG15_RS06295	COG1666	GTP binding
CEG15_RS06300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEG15_RS06305	COG0574	Belongs to the PEP-utilizing enzyme family
CEG15_RS06305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEG15_RS06320	COG2996	Protein conserved in bacteria
CEG15_RS06340	COG3008	intermembrane lipid transfer
CEG15_RS06345	COG2995	paraquat-inducible protein a
CEG15_RS06350	COG1132	(ABC) transporter
CEG15_RS06355	COG1956	GAF domain-containing protein
CEG15_RS06360	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CEG15_RS06375	COG0308	aminopeptidase N
CEG15_RS06385	COG2902	Dehydrogenase
CEG15_RS06390	COG0167	dihydroorotate dehydrogenase activity
CEG15_RS06410	COG0488	(ABC) transporter
CEG15_RS06425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEG15_RS06430	COG1067	ATP-dependent peptidase activity
CEG15_RS06435	COG3120	sequence-specific DNA binding
CEG15_RS06530	COG3278	Belongs to the heme-copper respiratory oxidase family
CEG15_RS06545	COG2010	Cytochrome c
CEG15_RS06555	COG2217	Heavy metal translocating P-type atpase
CEG15_RS06570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEG15_RS06575	COG0589	response to stress
CEG15_RS06600	COG3842	ATPase activity
CEG15_RS06605	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEG15_RS06610	COG1177	transmembrane transport
CEG15_RS06615	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEG15_RS06625	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEG15_RS06630	COG0004	ammonium transporteR
CEG15_RS06635	COG0488	(ABC) transporter
CEG15_RS06640	COG2197	response regulator
CEG15_RS06650	COG2271	Major facilitator Superfamily
CEG15_RS06655	COG1840	ABC-type Fe3 transport system, periplasmic component
CEG15_RS06665	COG3842	ATPase activity
CEG15_RS06670	COG0746	molybdenum cofactor guanylyltransferase activity
CEG15_RS06675	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEG15_RS06685	COG1940	carbohydrate kinase activity
CEG15_RS06690	COG3148	PFAM DTW domain containing protein
CEG15_RS06700	COG0840	transmembrane signaling receptor activity
CEG15_RS06705	COG0791	NLP P60 protein
CEG15_RS06715	COG3001	Fructosamine kinase
CEG15_RS06730	COG1793	dna ligase
CEG15_RS06735	COG4667	esterase of the alpha-beta hydrolase superfamily
CEG15_RS06750	COG0848	biopolymer transport protein
CEG15_RS06755	COG0811	peptide transport
CEG15_RS06760	COG0811	peptide transport
CEG15_RS06790	COG0625	glutathione transferase activity
CEG15_RS06800	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CEG15_RS06810	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEG15_RS06825	COG1115	amino acid carrier protein
CEG15_RS06830	COG1280	lysine exporter protein (LysE YggA)
CEG15_RS06835	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CEG15_RS06840	COG0477	Major facilitator Superfamily
CEG15_RS06845	COG0583	DNA-binding transcription factor activity
CEG15_RS06855	COG1643	Atp-dependent helicase
CEG15_RS06875	COG3706	GGDEF domain
CEG15_RS06890	COG0443	Heat shock 70 kDa protein
CEG15_RS06920	COG1609	Transcriptional regulator
CEG15_RS06925	COG2723	6-phospho-beta-galactosidase activity
CEG15_RS06930	COG0513	Belongs to the DEAD box helicase family
CEG15_RS06935	COG0243	molybdopterin cofactor binding
CEG15_RS06940	COG3005	denitrification pathway
CEG15_RS06945	COG1278	Cold shock
CEG15_RS06960	COG4191	Histidine kinase
CEG15_RS06960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEG15_RS06965	COG0471	metal ion transport
CEG15_RS06975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEG15_RS06995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEG15_RS07005	COG3768	UPF0283 membrane protein
CEG15_RS07010	COG3106	COG3106 Predicted ATPase
CEG15_RS07030	COG0494	nUDIX hydrolase
CEG15_RS07035	COG0814	amino acid
CEG15_RS07040	COG1760	l-serine dehydratase
CEG15_RS07050	COG2356	endonuclease I
CEG15_RS07055	COG0720	synthase
CEG15_RS07060	COG0840	transmembrane signaling receptor activity
CEG15_RS07065	COG0017	Asparaginyl-tRNA synthetase
CEG15_RS07075	COG2201	protein-glutamate methylesterase activity
CEG15_RS07080	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CEG15_RS07085	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CEG15_RS07090	COG0835	chemotaxis
CEG15_RS07100	COG0643	Histidine kinase
CEG15_RS07100	COG2198	Histidine kinase
CEG15_RS07110	COG0745	RESPONSE REGULATOR receiver
CEG15_RS07120	COG2770	Histidine kinase
CEG15_RS07120	COG3437	response regulator, receiver
CEG15_RS07125	COG1448	Aminotransferase
CEG15_RS07130	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CEG15_RS07140	COG0840	transmembrane signaling receptor activity
CEG15_RS07145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEG15_RS07150	COG1846	Transcriptional regulator
CEG15_RS07165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEG15_RS07170	COG3108	Peptidase M15
CEG15_RS07175	COG2989	Protein conserved in bacteria
CEG15_RS07205	COG1940	carbohydrate kinase activity
CEG15_RS07215	COG0748	coenzyme F420 binding
CEG15_RS07220	COG3721	Heme iron utilization protein
CEG15_RS07225	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CEG15_RS07230	COG0811	peptide transport
CEG15_RS07235	COG0848	biopolymer transport protein
CEG15_RS07245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEG15_RS07250	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CEG15_RS07255	COG1054	Belongs to the UPF0176 family
CEG15_RS07270	COG1621	beta-fructofuranosidase activity
CEG15_RS07280	COG1263	PTS System
CEG15_RS07280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEG15_RS07285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEG15_RS07290	COG2200	EAL domain
CEG15_RS07295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEG15_RS07300	COG0840	transmembrane signaling receptor activity
CEG15_RS07305	COG1294	oxidase, subunit
CEG15_RS07310	COG1271	oxidase subunit
CEG15_RS07335	COG3220	belongs to the UPF0276 family
CEG15_RS07355	COG1294	oxidase, subunit
CEG15_RS07365	COG0251	oxidation-reduction process
CEG15_RS07405	COG0835	chemotaxis
CEG15_RS07405	COG0784	Response regulator, receiver
CEG15_RS07415	COG4565	transcriptional regulatory protein
CEG15_RS07420	COG3290	protein histidine kinase activity
CEG15_RS07435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEG15_RS07460	COG3063	Type IV pilus biogenesis stability protein PilW
CEG15_RS07475	COG1451	nucleotide metabolic process
CEG15_RS07485	COG0583	DNA-binding transcription factor activity
CEG15_RS07505	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CEG15_RS07510	COG4139	cobalamin transport
CEG15_RS07515	COG2988	succinylglutamate desuccinylase activity
CEG15_RS07530	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CEG15_RS07535	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CEG15_RS07540	COG1073	alpha beta
CEG15_RS07540	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CEG15_RS07540	COG3064	Membrane
CEG15_RS07545	COG1073	alpha beta
CEG15_RS07545	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CEG15_RS07545	COG3064	Membrane
CEG15_RS07550	COG2994	toxin metabolic process
CEG15_RS07575	COG1823	symporter activity
CEG15_RS07580	COG2925	Exonuclease
CEG15_RS07585	COG1380	Effector of murein hydrolase LrgA
CEG15_RS07590	COG1346	cytolysis
CEG15_RS07600	COG5001	Diguanylate cyclase
CEG15_RS07615	COG0500	methyltransferase
CEG15_RS07625	COG0776	regulation of translation
CEG15_RS07630	COG0072	phenylalanine-tRNA ligase activity
CEG15_RS07630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEG15_RS07635	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CEG15_RS07675	COG0322	excinuclease ABC activity
CEG15_RS07680	COG2197	response regulator
CEG15_RS07685	COG0417	DNA replication proofreading
CEG15_RS07695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEG15_RS07700	COG3099	Belongs to the UPF0263 family
CEG15_RS07705	COG3097	Belongs to the UPF0267 family
CEG15_RS07715	COG1228	amidohydrolase
CEG15_RS07720	COG0010	Belongs to the arginase family
CEG15_RS07730	COG2986	histidine ammonia-lyase
CEG15_RS07745	COG0277	FAD linked oxidase domain protein
CEG15_RS07745	COG0247	lactate metabolic process
CEG15_RS07775	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEG15_RS07780	COG1960	acyl-CoA dehydrogenase activity
CEG15_RS07810	COG5001	Diguanylate cyclase
CEG15_RS07810	COG3300	MHYT domain
CEG15_RS07830	COG0784	Response regulator, receiver
CEG15_RS07830	COG5002	protein histidine kinase activity
CEG15_RS07840	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CEG15_RS07845	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CEG15_RS07850	COG2885	chlorophyll binding
CEG15_RS07855	COG0823	Involved in the tonB-independent uptake of proteins
CEG15_RS07870	COG0811	peptide transport
CEG15_RS07875	COG0824	Thioesterase
CEG15_RS07880	COG3790	cyd operon protein YbgE
CEG15_RS07885	COG4890	Cyd operon protein YbgT
CEG15_RS07890	COG1294	oxidase, subunit
CEG15_RS07895	COG1271	oxidase subunit
CEG15_RS07900	COG2255	four-way junction helicase activity
CEG15_RS07905	COG0632	four-way junction helicase activity
CEG15_RS07910	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CEG15_RS07915	COG0215	cysteine-tRNA ligase activity
CEG15_RS07920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEG15_RS07925	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEG15_RS07930	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CEG15_RS07935	COG3012	SEC-C Motif Domain Protein
CEG15_RS07950	COG1199	ATP-dependent helicase activity
CEG15_RS07960	COG3923	Primosomal replication protein n
CEG15_RS07970	COG0840	transmembrane signaling receptor activity
CEG15_RS07975	COG0708	Exodeoxyribonuclease III
CEG15_RS07980	COG4160	amino acid transport
CEG15_RS08010	COG1882	Formate acetyltransferase
CEG15_RS08025	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEG15_RS08035	COG3013	Belongs to the UPF0304 family
CEG15_RS08040	COG2766	serine protein kinase
CEG15_RS08045	COG2718	Belongs to the UPF0229 family
CEG15_RS08050	COG2719	SpoVR family
CEG15_RS08055	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CEG15_RS08070	COG1132	(ABC) transporter
CEG15_RS08075	COG2333	competence protein COMEC
CEG15_RS08075	COG0658	competence protein
CEG15_RS08085	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEG15_RS08090	COG1136	(ABC) transporter
CEG15_RS08095	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEG15_RS08105	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEG15_RS08120	COG1252	NADH dehydrogenase
CEG15_RS08125	COG3150	esterase
CEG15_RS08150	COG0537	adenosine 5'-monophosphoramidase activity
CEG15_RS08165	COG2186	Transcriptional regulator
CEG15_RS08170	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CEG15_RS08180	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CEG15_RS08185	COG2226	methyltransferase
CEG15_RS08195	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEG15_RS08200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CEG15_RS08210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEG15_RS08215	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CEG15_RS08220	COG0653	protein targeting
CEG15_RS08225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEG15_RS08235	COG4120	Belongs to the binding-protein-dependent transport system permease family
CEG15_RS08245	COG3092	negative regulation of chromosome organization
CEG15_RS08250	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEG15_RS08255	COG0857	belongs to the CobB CobQ family
CEG15_RS08255	COG0280	phosphate acetyltransferase
CEG15_RS08260	COG0435	Glutathione S-transferase
CEG15_RS08270	COG0444	Belongs to the ABC transporter superfamily
CEG15_RS08275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEG15_RS08280	COG0601	transmembrane transport
CEG15_RS08295	COG0784	Response regulator, receiver
CEG15_RS08295	COG5002	protein histidine kinase activity
CEG15_RS08320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEG15_RS08325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEG15_RS08345	COG1216	Glycosyl transferase, family 2
CEG15_RS08375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEG15_RS08380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEG15_RS08385	COG1028	Short-chain dehydrogenase reductase Sdr
CEG15_RS08420	COG3555	Aspartyl Asparaginyl beta-hydroxylase
CEG15_RS08435	COG0800	Aldolase
CEG15_RS08440	COG2610	gluconate transmembrane transporter activity
CEG15_RS08445	COG3265	gluconokinase activity
CEG15_RS08450	COG0129	dihydroxy-acid dehydratase activity
CEG15_RS08455	COG1609	Transcriptional regulator
CEG15_RS08470	COG5002	protein histidine kinase activity
CEG15_RS08470	COG3850	Histidine kinase
CEG15_RS08480	COG2985	domain, Protein
CEG15_RS08495	COG2194	sulfuric ester hydrolase activity
CEG15_RS08500	COG0642	Histidine kinase
CEG15_RS08505	COG0745	RESPONSE REGULATOR receiver
CEG15_RS08515	COG4221	oxidoreductase activity
CEG15_RS08525	COG1022	Amp-dependent synthetase and ligase
CEG15_RS08550	COG2203	Gaf domain
CEG15_RS08550	COG2199	diguanylate cyclase activity
CEG15_RS08565	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CEG15_RS08570	COG1946	Acyl-CoA thioesterase
CEG15_RS08575	COG1522	sequence-specific DNA binding
CEG15_RS08615	COG0318	PFAM AMP-dependent synthetase and ligase
CEG15_RS08625	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CEG15_RS08635	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CEG15_RS08640	COG1169	isochorismate synthase
CEG15_RS08650	COG0436	Aminotransferase
CEG15_RS08655	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CEG15_RS08660	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CEG15_RS08675	COG0616	signal peptide processing
CEG15_RS08680	COG1028	Short-chain dehydrogenase reductase Sdr
CEG15_RS08685	COG0835	chemotaxis
CEG15_RS08685	COG0784	Response regulator, receiver
CEG15_RS08690	COG1940	carbohydrate kinase activity
CEG15_RS08700	COG4667	esterase of the alpha-beta hydrolase superfamily
CEG15_RS08710	COG0733	neurotransmitter:sodium symporter activity
CEG15_RS08720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEG15_RS08720	COG1263	PTS System
CEG15_RS08725	COG0084	hydrolase, TatD family'
CEG15_RS08730	COG0470	DNA polymerase III
CEG15_RS08735	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CEG15_RS08740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEG15_RS08745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEG15_RS08770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEG15_RS08785	COG1399	metal-binding, possibly nucleic acid-binding protein
CEG15_RS08790	COG0424	maF-like protein
CEG15_RS08795	COG0564	pseudouridine synthase activity
CEG15_RS08800	COG1530	ribonuclease E activity
CEG15_RS08810	COG1012	belongs to the aldehyde dehydrogenase family
CEG15_RS08810	COG1454	alcohol dehydrogenase
CEG15_RS08815	COG2095	MarC family integral membrane protein
CEG15_RS08820	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEG15_RS08825	COG1757	Na H antiporter
CEG15_RS08840	COG3082	Protein of unknown function (DUF1414)
CEG15_RS08855	COG0243	molybdopterin cofactor binding
CEG15_RS08860	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CEG15_RS08875	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEG15_RS08880	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CEG15_RS08900	COG2853	Lipoprotein
CEG15_RS08915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEG15_RS08920	COG1138	Cytochrome C-type biogenesis protein
CEG15_RS08925	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CEG15_RS08935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEG15_RS08940	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEG15_RS08945	COG4133	protoheme IX ABC transporter activity
CEG15_RS08955	COG0835	chemotaxis
CEG15_RS08965	COG1192	Involved in chromosome partitioning
CEG15_RS08970	COG2201	protein-glutamate methylesterase activity
CEG15_RS08975	COG0643	Histidine kinase
CEG15_RS08975	COG0784	Response regulator, receiver
CEG15_RS08975	COG2198	Histidine kinase
CEG15_RS08980	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CEG15_RS09005	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CEG15_RS09010	COG2062	phosphohistidine phosphatase, SixA
CEG15_RS09015	COG1025	Belongs to the peptidase M16 family
CEG15_RS09020	COG3102	Protein conserved in bacteria
CEG15_RS09045	COG1918	ferrous iron import across plasma membrane
CEG15_RS09050	COG4977	sequence-specific DNA binding
CEG15_RS09055	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CEG15_RS09060	COG1121	(ABC) transporter
CEG15_RS09065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEG15_RS09080	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEG15_RS09085	COG0567	Dehydrogenase, E1 component
CEG15_RS09100	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CEG15_RS09115	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEG15_RS09125	COG0033	Phosphoglucomutase
CEG15_RS09130	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CEG15_RS09135	COG0596	Alpha beta hydrolase
CEG15_RS09150	COG1346	cytolysis
CEG15_RS09160	COG0583	DNA-binding transcription factor activity
CEG15_RS09170	COG0735	belongs to the Fur family
CEG15_RS09175	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEG15_RS09180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEG15_RS09185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEG15_RS09190	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CEG15_RS09190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEG15_RS09195	COG0431	NADPH-dependent FMN reductase
CEG15_RS09205	COG3101	peptidyl-lysine hydroxylation
CEG15_RS09210	COG2860	membrane
CEG15_RS09215	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEG15_RS09220	COG2890	protein-(glutamine-N5) methyltransferase activity
CEG15_RS09225	COG2840	Smr protein MutS2
CEG15_RS09235	COG1684	flagellar biosynthetic protein fliR
CEG15_RS09240	COG1987	bacterial-type flagellum assembly
CEG15_RS09290	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CEG15_RS09300	COG1677	Flagellar hook-basal body complex protein FliE
CEG15_RS09320	COG1516	flagellar protein fliS
CEG15_RS09330	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CEG15_RS09355	COG2837	iron assimilation
CEG15_RS09380	COG1393	Belongs to the ArsC family
CEG15_RS09400	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CEG15_RS09415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEG15_RS09440	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEG15_RS09460	COG1196	nuclear chromosome segregation
CEG15_RS09465	COG1074	ATP-dependent DNA helicase activity
CEG15_RS09470	COG0210	DNA helicase
CEG15_RS09525	COG0537	adenosine 5'-monophosphoramidase activity
CEG15_RS09540	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CEG15_RS09545	COG0076	glutamate decarboxylase activity
CEG15_RS09565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEG15_RS09585	COG4783	chaperone-mediated protein folding
CEG15_RS09590	COG1393	Belongs to the ArsC family
CEG15_RS09610	COG2233	PERMEase
CEG15_RS09615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEG15_RS09625	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CEG15_RS09630	COG2912	Transglutaminase-like superfamily
CEG15_RS09635	COG3094	Invasion gene expression up-regulator, SirB
CEG15_RS09640	COG2890	protein-(glutamine-N5) methyltransferase activity
CEG15_RS09645	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CEG15_RS09650	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CEG15_RS09655	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CEG15_RS09660	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CEG15_RS09665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEG15_RS09670	COG0193	aminoacyl-tRNA hydrolase activity
CEG15_RS09775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CEG15_RS09785	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEG15_RS09785	COG3951	Flagellar rod assembly protein muramidase FlgJ
CEG15_RS09790	COG1706	bacterial-type flagellum-dependent cell motility
CEG15_RS09795	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CEG15_RS09805	COG4787	bacterial-type flagellum-dependent cell motility
CEG15_RS09810	COG1749	Flagellar hook protein flgE
CEG15_RS09825	COG1815	bacterial-type flagellum-dependent cell motility
CEG15_RS09835	COG0784	Response regulator, receiver
CEG15_RS09835	COG0835	chemotaxis
CEG15_RS09845	COG2747	anti-sigma28 factor FlgM
CEG15_RS09890	COG2217	Heavy metal translocating P-type atpase
CEG15_RS09890	COG2608	mercury ion transmembrane transporter activity
CEG15_RS09915	COG1187	pseudouridine synthase activity
CEG15_RS09920	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEG15_RS09925	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEG15_RS09930	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CEG15_RS09935	COG0121	glutamine amidotransferase
CEG15_RS09940	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEG15_RS09960	COG0328	RNA-DNA hybrid ribonuclease activity
CEG15_RS09965	COG2226	methyltransferase
CEG15_RS09970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEG15_RS09975	COG0741	lytic transglycosylase activity
CEG15_RS09975	COG1388	LysM domain
CEG15_RS09985	COG3021	interspecies interaction between organisms
CEG15_RS09990	COG0347	Belongs to the P(II) protein family
CEG15_RS10000	COG0037	tRNA processing
CEG15_RS10005	COG0825	malonyl-CoA metabolic process
CEG15_RS10010	COG0587	DNA-directed DNA polymerase activity
CEG15_RS10020	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEG15_RS10030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEG15_RS10035	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEG15_RS10040	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CEG15_RS10050	COG0750	zinc metalloprotease
CEG15_RS10055	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CEG15_RS10060	COG0575	Belongs to the CDS family
CEG15_RS10065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CEG15_RS10070	COG0233	cytoplasmic translational termination
CEG15_RS10080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEG15_RS10085	COG0052	Belongs to the universal ribosomal protein uS2 family
CEG15_RS10090	COG0024	Methionine aminopeptidase
CEG15_RS10095	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CEG15_RS10105	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CEG15_RS10110	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CEG15_RS10115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEG15_RS10135	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEG15_RS10135	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEG15_RS10140	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CEG15_RS10145	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CEG15_RS10150	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CEG15_RS10160	COG1073	alpha beta
CEG15_RS10165	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CEG15_RS10170	COG2252	PERMEase
CEG15_RS10175	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEG15_RS10180	COG4067	protein conserved in archaea
CEG15_RS10180	COG0189	ligase activity
CEG15_RS10185	COG0189	ligase activity
CEG15_RS10195	COG0733	neurotransmitter:sodium symporter activity
CEG15_RS10200	COG2203	Gaf domain
CEG15_RS10200	COG5001	Diguanylate cyclase
CEG15_RS10200	COG3706	GGDEF domain
CEG15_RS10200	COG4251	negative regulation of phosphorylation
CEG15_RS10210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEG15_RS10220	COG1477	protein flavinylation
CEG15_RS10255	COG0271	Belongs to the BolA IbaG family
CEG15_RS10275	COG2211	Major facilitator Superfamily
CEG15_RS10285	COG1595	DNA-templated transcription, initiation
CEG15_RS10300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEG15_RS10310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEG15_RS10315	COG2166	iron-sulfur cluster assembly
CEG15_RS10320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CEG15_RS10325	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CEG15_RS10335	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CEG15_RS10335	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEG15_RS10345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEG15_RS10350	COG1074	ATP-dependent DNA helicase activity
CEG15_RS10355	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CEG15_RS10370	COG3141	response to X-ray
CEG15_RS10375	COG2171	N-acyltransferase activity
CEG15_RS10385	COG0456	acetyltransferase
CEG15_RS10405	COG1609	Transcriptional regulator
CEG15_RS10415	COG1085	galactose-1-phosphate uridylyltransferase
CEG15_RS10420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEG15_RS10425	COG0534	Mate efflux family protein
CEG15_RS10435	COG0784	Response regulator, receiver
CEG15_RS10435	COG3437	response regulator, receiver
CEG15_RS10440	COG1022	Amp-dependent synthetase and ligase
CEG15_RS10445	COG4628	conserved protein (DUF2132)
CEG15_RS10450	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEG15_RS10455	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CEG15_RS10465	COG0560	Phosphoserine phosphatase
CEG15_RS10475	COG0813	purine-nucleoside phosphorylase activity
CEG15_RS10480	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CEG15_RS10485	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CEG15_RS10490	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CEG15_RS10495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEG15_RS10500	COG0084	hydrolase, TatD family'
CEG15_RS10505	COG3022	response to hydroperoxide
CEG15_RS10510	COG1115	amino acid carrier protein
CEG15_RS10525	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CEG15_RS10530	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CEG15_RS10535	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CEG15_RS10540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CEG15_RS10545	COG0083	homoserine kinase activity
CEG15_RS10560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CEG15_RS10565	COG0745	RESPONSE REGULATOR receiver
CEG15_RS10575	COG5002	protein histidine kinase activity
CEG15_RS10575	COG0784	Response regulator, receiver
CEG15_RS10575	COG2198	Histidine kinase
CEG15_RS10580	COG1242	4 iron, 4 sulfur cluster binding
CEG15_RS10585	COG0070	glutamate synthase
CEG15_RS10585	COG0069	glutamate synthase activity
CEG15_RS10585	COG0067	glutamate synthase
CEG15_RS10595	COG0069	glutamate synthase activity
CEG15_RS10595	COG0067	glutamate synthase
CEG15_RS10595	COG0070	glutamate synthase
CEG15_RS10600	COG0493	'glutamate synthase
CEG15_RS10610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CEG15_RS10620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEG15_RS10625	COG2860	membrane
CEG15_RS10630	COG0583	DNA-binding transcription factor activity
CEG15_RS10635	COG0730	response to heat
CEG15_RS10640	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CEG15_RS10645	COG0505	Belongs to the CarA family
CEG15_RS10650	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CEG15_RS10655	COG0494	nUDIX hydrolase
CEG15_RS10660	COG0653	protein targeting
CEG15_RS10670	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CEG15_RS10675	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CEG15_RS10680	COG0849	cell division
CEG15_RS10685	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CEG15_RS10690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEG15_RS10695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CEG15_RS10700	COG0772	Belongs to the SEDS family
CEG15_RS10705	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEG15_RS10715	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEG15_RS10720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEG15_RS10725	COG0768	penicillin binding
CEG15_RS10730	COG3116	cell division
CEG15_RS10735	COG0275	rRNA processing
CEG15_RS10745	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CEG15_RS10750	COG3107	peptidoglycan biosynthetic process
CEG15_RS10755	COG0792	nuclease activity
CEG15_RS10760	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEG15_RS10770	COG2969	positive regulation of protein catabolic process
CEG15_RS10775	COG0625	glutathione transferase activity
CEG15_RS10780	COG2857	Cytochrome c1
CEG15_RS10785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CEG15_RS10790	COG0723	plastoquinol--plastocyanin reductase activity
CEG15_RS10800	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CEG15_RS10810	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CEG15_RS10815	COG3105	Protein conserved in bacteria
CEG15_RS10820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEG15_RS10825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEG15_RS10830	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CEG15_RS10835	COG0187	DNA topoisomerase II activity
CEG15_RS10840	COG3150	esterase
CEG15_RS10850	COG3151	Protein conserved in bacteria
CEG15_RS10855	COG0494	nUDIX hydrolase
CEG15_RS10860	COG1538	Outer membrane efflux protein
CEG15_RS10870	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CEG15_RS10885	COG3025	triphosphatase activity
CEG15_RS10890	COG1392	Phosphate transport regulator
CEG15_RS10895	COG0306	phosphate transporter
CEG15_RS10900	COG4991	sh3 domain protein
CEG15_RS10910	COG3409	Peptidoglycan-binding domain 1 protein
CEG15_RS10910	COG3267	Type II secretory pathway component ExeA
CEG15_RS10915	COG0617	tRNA 3'-terminal CCA addition
CEG15_RS10925	COG0504	CTP synthase activity
CEG15_RS10930	COG3956	TIGRFAM MazG family protein
CEG15_RS10935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEG15_RS10940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEG15_RS10945	COG2205	protein histidine kinase activity
CEG15_RS10945	COG3850	Histidine kinase
CEG15_RS10945	COG4999	Histidine kinase
CEG15_RS10945	COG3437	response regulator, receiver
CEG15_RS10950	COG0736	holo-[acyl-carrier-protein] synthase activity
CEG15_RS10955	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CEG15_RS10960	COG1381	Involved in DNA repair and RecF pathway recombination
CEG15_RS10965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CEG15_RS10970	COG0571	ribonuclease III activity
CEG15_RS10980	COG0481	GTPase activity
CEG15_RS10985	COG3086	response to oxidative stress
CEG15_RS11000	COG1595	DNA-templated transcription, initiation
CEG15_RS11005	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CEG15_RS11015	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CEG15_RS11035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEG15_RS11040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEG15_RS11045	COG3079	Belongs to the UPF0149 family
CEG15_RS11050	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CEG15_RS11060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEG15_RS11070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEG15_RS11080	COG0028	Belongs to the TPP enzyme family
CEG15_RS11085	COG1022	Amp-dependent synthetase and ligase
CEG15_RS11110	COG0473	3-isopropylmalate dehydrogenase activity
CEG15_RS11120	COG0066	3-isopropylmalate dehydratase activity
CEG15_RS11185	COG0795	lipopolysaccharide-transporting ATPase activity
CEG15_RS11190	COG0795	lipopolysaccharide-transporting ATPase activity
CEG15_RS11195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEG15_RS11200	COG2927	DNA polymerase III (CHI subunit)
CEG15_RS11205	COG0525	valine-tRNA ligase activity
CEG15_RS11210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEG15_RS11215	COG0564	pseudouridine synthase activity
CEG15_RS11225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEG15_RS11235	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CEG15_RS11250	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CEG15_RS11255	COG0251	oxidation-reduction process
CEG15_RS11270	COG0204	Acyl-transferase
CEG15_RS11275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEG15_RS11280	COG5007	Belongs to the BolA IbaG family
CEG15_RS11290	COG2854	intermembrane phospholipid transfer
CEG15_RS11295	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CEG15_RS11300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEG15_RS11305	COG1127	ABC transporter
CEG15_RS11315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CEG15_RS11315	COG0517	IMP dehydrogenase activity
CEG15_RS11320	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CEG15_RS11330	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CEG15_RS11335	COG1137	ATPase activity
CEG15_RS11345	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEG15_RS11350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_RS11355	COG1660	Displays ATPase and GTPase activities
CEG15_RS11360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_RS11365	COG2239	Acts as a magnesium transporter
CEG15_RS11370	COG0312	modulator of DNA gyrase
CEG15_RS11375	COG3028	Belongs to the UPF0307 family
CEG15_RS11380	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CEG15_RS11385	COG1178	ABC-type Fe3 transport system permease component
CEG15_RS11395	COG0163	prenyltransferase activity
CEG15_RS11400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEG15_RS11405	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CEG15_RS11410	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CEG15_RS11420	COG2105	PFAM AIG2 family protein
CEG15_RS11425	COG2911	Protein conserved in bacteria
CEG15_RS11430	COG0729	surface antigen
CEG15_RS11435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEG15_RS11440	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CEG15_RS11475	COG0529	Catalyzes the synthesis of activated sulfate
CEG15_RS11480	COG2895	sulfate adenylyltransferase (ATP) activity
CEG15_RS11485	COG0175	sulfate reduction
CEG15_RS11490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEG15_RS11490	COG1648	precorrin-2 dehydrogenase activity
CEG15_RS11495	COG0737	Belongs to the 5'-nucleotidase family
CEG15_RS11535	COG0513	Belongs to the DEAD box helicase family
CEG15_RS11540	COG2153	protein acetylation
CEG15_RS11545	COG3266	domain, Protein
CEG15_RS11545	COG3061	Opacity-associated protein A
CEG15_RS11550	COG0545	Peptidyl-prolyl cis-trans isomerase
CEG15_RS11555	COG0203	ribosomal protein L17
CEG15_RS11560	COG0202	RNA polymerase activity
CEG15_RS11565	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEG15_RS11570	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CEG15_RS11575	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEG15_RS11580	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEG15_RS11585	COG0201	protein transport
CEG15_RS11590	COG0200	Binds to the 23S rRNA
CEG15_RS11595	COG1841	ribosomal large subunit assembly
CEG15_RS11600	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CEG15_RS11610	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEG15_RS11615	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEG15_RS11620	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEG15_RS11625	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CEG15_RS11630	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CEG15_RS11640	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CEG15_RS11650	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CEG15_RS11665	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEG15_RS11670	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEG15_RS11680	COG0088	Forms part of the polypeptide exit tunnel
CEG15_RS11685	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CEG15_RS11690	COG0051	transcription antitermination factor activity, RNA binding
CEG15_RS11695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEG15_RS11700	COG0557	exoribonuclease II activity
CEG15_RS11705	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CEG15_RS11715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEG15_RS11725	COG1047	Peptidyl-prolyl cis-trans
CEG15_RS11730	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CEG15_RS11740	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEG15_RS11745	COG0488	(ABC) transporter
CEG15_RS11755	COG0429	hydrolase of the alpha beta-hydrolase fold
CEG15_RS11765	COG3954	Phosphoribulokinase
CEG15_RS11770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEG15_RS11780	COG1012	belongs to the aldehyde dehydrogenase family
CEG15_RS11790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEG15_RS11805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEG15_RS11815	COG0583	DNA-binding transcription factor activity
CEG15_RS11830	COG0180	Tryptophanyl-tRNA synthetase
CEG15_RS11835	COG0546	phosphoglycolate phosphatase activity
CEG15_RS11840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEG15_RS11845	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CEG15_RS11855	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CEG15_RS11860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CEG15_RS11890	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CEG15_RS11900	COG0678	peroxiredoxin activity
CEG15_RS11900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEG15_RS11905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEG15_RS11915	COG0165	Argininosuccinate lyase
CEG15_RS11915	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CEG15_RS11920	COG0137	argininosuccinate synthase activity
CEG15_RS11925	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEG15_RS11930	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEG15_RS11935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEG15_RS11940	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CEG15_RS11950	COG1045	serine acetyltransferase
CEG15_RS11955	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEG15_RS11965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEG15_RS11970	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CEG15_RS11975	COG1053	succinate dehydrogenase
CEG15_RS11980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEG15_RS11985	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CEG15_RS11995	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEG15_RS12000	COG1509	lysine 2,3-aminomutase activity
CEG15_RS12015	COG0459	protein refolding
CEG15_RS12020	COG3335	DDE superfamily endonuclease
CEG15_RS12030	COG0583	DNA-binding transcription factor activity
CEG15_RS12040	COG0459	protein refolding
CEG15_RS12045	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CEG15_RS12075	COG0534	Mate efflux family protein
CEG15_RS12080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CEG15_RS12085	COG1575	Belongs to the MenA family. Type 1 subfamily
CEG15_RS12090	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CEG15_RS12095	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CEG15_RS12105	COG1609	Transcriptional regulator
CEG15_RS12110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEG15_RS12120	COG0281	malic enzyme
CEG15_RS12130	COG0626	cystathionine gamma-synthase activity
CEG15_RS12135	COG0460	homoserine dehydrogenase
CEG15_RS12135	COG0527	aspartate kinase activity
CEG15_RS12140	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEG15_RS12145	COG3074	FtsZ-dependent cytokinesis
CEG15_RS12150	COG1494	fructose-1,6-bisphosphatase
CEG15_RS12155	COG0205	6-phosphofructokinase activity
CEG15_RS12160	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CEG15_RS12170	COG0745	RESPONSE REGULATOR receiver
CEG15_RS12175	COG2205	protein histidine kinase activity
CEG15_RS12180	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEG15_RS12185	COG1278	Cold shock
CEG15_RS12190	COG3030	protein affecting phage T7 exclusion by the F plasmid
CEG15_RS12195	COG1027	Aspartate ammonia-lyase
CEG15_RS12200	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CEG15_RS12205	COG1288	antiporter activity
CEG15_RS12215	COG0549	Belongs to the carbamate kinase family
CEG15_RS12220	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CEG15_RS12230	COG0540	Belongs to the ATCase OTCase family
CEG15_RS12235	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CEG15_RS12240	COG1438	arginine binding
CEG15_RS12245	COG4232	protein-disulfide reductase activity
CEG15_RS12265	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEG15_RS12270	COG2205	protein histidine kinase activity
CEG15_RS12270	COG2198	Histidine kinase
CEG15_RS12270	COG0784	Response regulator, receiver
CEG15_RS12275	COG2814	Major facilitator Superfamily
CEG15_RS12290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEG15_RS12295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CEG15_RS12300	COG0511	ligase activity, forming carbon-carbon bonds
CEG15_RS12305	COG0439	Biotin carboxylase
CEG15_RS12310	COG2264	protein methyltransferase activity
CEG15_RS12315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEG15_RS12320	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CEG15_RS12325	COG0840	transmembrane signaling receptor activity
CEG15_RS12330	COG0789	Transcriptional regulator
CEG15_RS12335	COG0138	bifunctional purine biosynthesis protein purh
CEG15_RS12340	COG0151	Belongs to the GarS family
CEG15_RS12350	COG0776	regulation of translation
CEG15_RS12355	COG1253	flavin adenine dinucleotide binding
CEG15_RS12370	COG3068	Protein conserved in bacteria
CEG15_RS12375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEG15_RS12380	COG0668	transmembrane transport
CEG15_RS12385	COG0840	transmembrane signaling receptor activity
CEG15_RS12390	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CEG15_RS12395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEG15_RS12425	COG0438	transferase activity, transferring glycosyl groups
CEG15_RS12440	COG1216	Glycosyl transferase, family 2
CEG15_RS12480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEG15_RS12505	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEG15_RS12515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEG15_RS12540	COG3754	Rhamnan synthesis protein F
CEG15_RS12570	COG0463	Glycosyl transferase, family 2
CEG15_RS12580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CEG15_RS12590	COG0028	Belongs to the TPP enzyme family
CEG15_RS12625	COG5433	transposase activity
CEG15_RS12640	COG1682	transport, permease protein
CEG15_RS12675	COG3307	-O-antigen
CEG15_RS12680	COG0859	PFAM glycosyl transferase family 9
CEG15_RS12695	COG1519	Transferase
CEG15_RS12705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CEG15_RS12720	COG3642	lipopolysaccharide core region biosynthetic process
CEG15_RS12725	COG0859	PFAM glycosyl transferase family 9
CEG15_RS12730	COG0463	Glycosyl transferase, family 2
CEG15_RS12735	COG0859	PFAM glycosyl transferase family 9
CEG15_RS12740	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEG15_RS12745	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CEG15_RS12755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEG15_RS12760	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CEG15_RS12765	COG2003	Belongs to the UPF0758 family
CEG15_RS12770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEG15_RS12775	COG1309	transcriptional regulator
CEG15_RS12780	COG1560	Kdo2-lipid A biosynthetic process
CEG15_RS12785	COG1560	Kdo2-lipid A biosynthetic process
CEG15_RS12790	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CEG15_RS12795	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CEG15_RS12800	COG1561	YicC-like family, N-terminal region
CEG15_RS12810	COG0612	Peptidase, M16
CEG15_RS12815	COG2862	Uncharacterized protein family, UPF0114
CEG15_RS12830	COG1120	ATPase activity
CEG15_RS12835	COG4774	siderophore transport
CEG15_RS12840	COG1132	(ABC) transporter
CEG15_RS12845	COG1263	PTS System
CEG15_RS12845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEG15_RS12850	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CEG15_RS12870	COG0514	ATP-dependent DNA helicase (RecQ)
CEG15_RS12875	COG2962	Rard protein
CEG15_RS12880	COG0405	Gamma-glutamyltransferase
CEG15_RS12890	COG1280	lysine exporter protein (LysE YggA)
CEG15_RS12895	COG0210	DNA helicase
CEG15_RS12900	COG0339	signal peptide processing
CEG15_RS12905	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CEG15_RS12910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEG15_RS12930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEG15_RS12935	COG0601	transmembrane transport
CEG15_RS12985	COG1309	transcriptional regulator
CEG15_RS12990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEG15_RS12995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEG15_RS13000	COG2960	long-chain fatty acid transporting porin activity
CEG15_RS13005	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CEG15_RS13015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEG15_RS13025	COG3078	GTPase activator activity
CEG15_RS13045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEG15_RS13045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CEG15_RS13055	COG0084	hydrolase, TatD family'
CEG15_RS13060	COG0805	protein transport
CEG15_RS13065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEG15_RS13070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEG15_RS13075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CEG15_RS13085	COG2226	methyltransferase
CEG15_RS13090	COG1322	Protein conserved in bacteria
CEG15_RS13110	COG2160	L-arabinose isomerase activity
CEG15_RS13120	COG1069	ribulokinase activity
CEG15_RS13130	COG1879	ABC-type sugar transport system periplasmic component
CEG15_RS13135	COG1129	ABC transporter
CEG15_RS13140	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEG15_RS13180	COG2124	cytochrome p450
CEG15_RS13185	COG0477	Major facilitator Superfamily
CEG15_RS13195	COG0251	oxidation-reduction process
CEG15_RS13205	COG0251	oxidation-reduction process
CEG15_RS13210	COG3048	D-serine ammonia-lyase activity
CEG15_RS13215	COG2610	gluconate transmembrane transporter activity
CEG15_RS13220	COG0583	DNA-binding transcription factor activity
CEG15_RS13275	COG2081	HI0933 family
CEG15_RS13290	COG1528	Iron-storage protein
CEG15_RS13295	COG0589	response to stress
CEG15_RS13310	COG0742	ribosomal rna small subunit methyltransferase
CEG15_RS13315	COG1522	sequence-specific DNA binding
CEG15_RS13335	COG0006	proline dipeptidase activity
CEG15_RS13335	COG0006	proline dipeptidase activity
CEG15_RS13340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEG15_RS13345	COG2022	thiamine diphosphate biosynthetic process
CEG15_RS13350	COG2104	thiamine diphosphate biosynthetic process
CEG15_RS13355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEG15_RS13360	COG0352	thiamine-phosphate diphosphorylase activity
CEG15_RS13450	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CEG15_RS13455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CEG15_RS13460	COG1739	Uncharacterized protein family UPF0029
CEG15_RS13470	COG0183	Belongs to the thiolase family
CEG15_RS13475	COG0583	DNA-binding transcription factor activity
CEG15_RS13480	COG2814	Major facilitator Superfamily
CEG15_RS13490	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CEG15_RS13495	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEG15_RS13500	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEG15_RS13505	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEG15_RS13510	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEG15_RS13515	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEG15_RS13530	COG3312	ion transport
CEG15_RS13535	COG1475	DNA binding
CEG15_RS13540	COG1192	Involved in chromosome partitioning
CEG15_RS13550	COG0445	tRNA wobble uridine modification
CEG15_RS13580	COG2084	Dehydrogenase
CEG15_RS13585	COG0814	amino acid
CEG15_RS13615	COG0583	DNA-binding transcription factor activity
CEG15_RS13620	COG2910	NAD(P)H-binding
CEG15_RS13630	COG3304	Inner membrane component domain
CEG15_RS13650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEG15_RS13655	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CEG15_RS13675	COG0363	glucosamine-6-phosphate deaminase activity
CEG15_RS13685	COG0739	heme binding
CEG15_RS13690	COG2213	PTS system mannitol-specific
CEG15_RS13690	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_RS13695	COG0246	Mannitol dehydrogenase
CEG15_RS13700	COG3722	fumarate hydratase activity
CEG15_RS13710	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CEG15_RS13715	COG1301	dicarboxylic acid transport
CEG15_RS13720	COG2259	Doxx family
CEG15_RS13745	COG1846	Transcriptional regulator
CEG15_RS13755	COG3046	protein related to deoxyribodipyrimidine photolyase
CEG15_RS13760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEG15_RS13765	COG0842	Transport permease protein
CEG15_RS13770	COG1131	(ABC) transporter
CEG15_RS13785	COG3842	ATPase activity
CEG15_RS13795	COG1175	transmembrane transport
CEG15_RS13815	COG0513	Belongs to the DEAD box helicase family
CEG15_RS13820	COG0251	oxidation-reduction process
CEG15_RS13825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEG15_RS13835	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEG15_RS13840	COG1328	CTP reductase activity
CEG15_RS13850	COG2130	NADP-dependent
CEG15_RS13855	COG1309	transcriptional regulator
CEG15_RS13870	COG0745	RESPONSE REGULATOR receiver
CEG15_RS13880	COG0564	pseudouridine synthase activity
CEG15_RS13940	COG3829	transcription factor binding
CEG15_RS13965	COG3501	Rhs element vgr protein
CEG15_RS14015	COG0471	metal ion transport
CEG15_RS14020	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CEG15_RS14030	COG2188	Transcriptional regulator
CEG15_RS14035	COG1131	(ABC) transporter
CEG15_RS14045	COG0840	transmembrane signaling receptor activity
CEG15_RS14065	COG0671	phosphoesterase, PA-phosphatase related
CEG15_RS14075	COG1132	(ABC) transporter
CEG15_RS14095	COG3623	hexulose-6-phosphate isomerase
CEG15_RS14100	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CEG15_RS14105	COG0561	phosphatase activity
CEG15_RS14165	COG0366	Alpha amylase catalytic
CEG15_RS14175	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CEG15_RS14185	COG1999	signal sequence binding
CEG15_RS14205	COG0786	glutamate:sodium symporter activity
CEG15_RS14230	COG1566	PFAM secretion protein HlyD family protein
CEG15_RS14255	COG0813	purine-nucleoside phosphorylase activity
CEG15_RS14260	COG3272	Protein of unknown function (DUF1722)
CEG15_RS14265	COG0789	Transcriptional regulator
CEG15_RS14270	COG0415	Belongs to the DNA photolyase family
CEG15_RS14275	COG1376	ErfK ybiS ycfS ynhG family protein
CEG15_RS14275	COG1388	LysM domain
CEG15_RS14285	COG0513	Belongs to the DEAD box helicase family
CEG15_RS14315	COG2267	carboxylic ester hydrolase activity
CEG15_RS14325	COG0366	Alpha amylase catalytic
CEG15_RS14330	COG4989	oxidoreductase activity
CEG15_RS14340	COG1136	(ABC) transporter
CEG15_RS14340	COG0577	efflux transmembrane transporter activity
CEG15_RS14345	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEG15_RS14360	COG2972	Histidine kinase
CEG15_RS14360	COG0745	RESPONSE REGULATOR receiver
CEG15_RS14365	COG3279	Response regulator of the LytR AlgR family
CEG15_RS14370	COG5001	Diguanylate cyclase
CEG15_RS14370	COG4251	negative regulation of phosphorylation
CEG15_RS14370	COG3706	GGDEF domain
CEG15_RS14370	COG2203	Gaf domain
CEG15_RS14380	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CEG15_RS14390	COG3437	response regulator, receiver
CEG15_RS14395	COG3437	response regulator, receiver
CEG15_RS14395	COG4999	Histidine kinase
CEG15_RS14395	COG2205	protein histidine kinase activity
CEG15_RS14395	COG3850	Histidine kinase
CEG15_RS14405	COG0531	amino acid
CEG15_RS14420	COG1151	hydroxylamine reductase activity
CEG15_RS14425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEG15_RS14435	COG5002	protein histidine kinase activity
CEG15_RS14435	COG2205	protein histidine kinase activity
CEG15_RS14435	COG0784	Response regulator, receiver
CEG15_RS14455	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEG15_RS14465	COG1609	Transcriptional regulator
CEG15_RS14490	COG0673	inositol 2-dehydrogenase activity
CEG15_RS14495	COG1765	OsmC-like protein
CEG15_RS14500	COG0110	maltose O-acetyltransferase activity
CEG15_RS14515	COG0583	DNA-binding transcription factor activity
CEG15_RS14525	COG0583	DNA-binding transcription factor activity
CEG15_RS14530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEG15_RS14535	COG3186	Phenylalanine-4-hydroxylase
CEG15_RS14540	COG2154	pterin-4-alpha-carbinolamine dehydratase
CEG15_RS14545	COG0840	transmembrane signaling receptor activity
CEG15_RS14550	COG0534	Mate efflux family protein
CEG15_RS14555	COG2207	Transcriptional regulator
CEG15_RS14560	COG0784	Response regulator, receiver
CEG15_RS14560	COG3437	response regulator, receiver
CEG15_RS14565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEG15_RS14565	COG4191	Histidine kinase
CEG15_RS14575	COG2814	Major facilitator Superfamily
CEG15_RS14585	COG0443	Heat shock 70 kDa protein
CEG15_RS14600	COG3240	lipase activity
CEG15_RS14610	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CEG15_RS14615	COG5380	lipid catabolic process
CEG15_RS14645	COG4607	ABC-type enterochelin transport system periplasmic component
CEG15_RS14650	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEG15_RS14655	COG4605	iron ion homeostasis
CEG15_RS14660	COG4604	ABC transporter, ATP-binding protein
CEG15_RS14665	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEG15_RS14675	COG2153	protein acetylation
CEG15_RS14680	COG0697	spore germination
CEG15_RS14685	COG0387	Pfam Sodium calcium exchanger
CEG15_RS14690	COG0861	Integral membrane protein TerC family
CEG15_RS14705	COG3706	GGDEF domain
CEG15_RS14710	COG4974	Belongs to the 'phage' integrase family
CEG15_RS14740	COG1192	Involved in chromosome partitioning
CEG15_RS14765	COG3344	reverse transcriptase
CEG15_RS14780	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CEG15_RS14800	COG3344	reverse transcriptase
CEG15_RS14820	COG0509	glycine decarboxylation via glycine cleavage system
CEG15_RS14825	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEG15_RS14835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEG15_RS14850	COG0612	Peptidase, M16
CEG15_RS14865	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CEG15_RS14865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEG15_RS14865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEG15_RS14870	COG1105	Belongs to the carbohydrate kinase PfkB family
CEG15_RS14875	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_RS14875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_RS14880	COG1609	Transcriptional regulator
CEG15_RS14885	COG0420	3'-5' exonuclease activity
CEG15_RS14890	COG0419	ATPase involved in DNA repair
CEG15_RS14895	COG0784	Response regulator, receiver
CEG15_RS14895	COG2205	protein histidine kinase activity
CEG15_RS14900	COG0156	8-amino-7-oxononanoate synthase activity
CEG15_RS14910	COG0038	chloride channel
CEG15_RS14915	COG0523	cobalamin synthesis protein
CEG15_RS14930	COG0577	efflux transmembrane transporter activity
CEG15_RS14930	COG1136	(ABC) transporter
CEG15_RS14945	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEG15_RS14955	COG3675	Pfam Lipase (class 3)
CEG15_RS14975	COG3730	PTS system glucitol sorbitol-specific
CEG15_RS14990	COG1028	Short-chain dehydrogenase reductase Sdr
CEG15_RS14995	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEG15_RS15000	COG1349	DNA-binding transcription factor activity
CEG15_RS15005	COG3730	PTS system glucitol sorbitol-specific
CEG15_RS15020	COG3842	ATPase activity
CEG15_RS15030	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEG15_RS15040	COG2182	Extracellular solute-binding protein
CEG15_RS15045	COG1175	transmembrane transport
CEG15_RS15050	COG3833	ABC-type maltose transport systems, permease component
CEG15_RS15075	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEG15_RS15080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEG15_RS15090	COG3005	denitrification pathway
CEG15_RS15100	COG0243	molybdopterin cofactor binding
CEG15_RS15110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEG15_RS15115	COG3850	Histidine kinase
CEG15_RS15120	COG2197	response regulator
CEG15_RS15125	COG3069	C4-dicarboxylate transmembrane transporter activity
CEG15_RS15150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEG15_RS15160	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CEG15_RS15165	COG0513	Belongs to the DEAD box helicase family
CEG15_RS15235	COG1484	DNA-dependent DNA replication
CEG15_RS15285	COG3772	lysozyme
CEG15_RS15485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEG15_RS15490	COG0242	peptide deformylase activity
CEG15_RS15525	COG0346	lactoylglutathione lyase activity
CEG15_RS15555	COG0625	glutathione transferase activity
CEG15_RS15580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEG15_RS15680	COG2161	toxin-antitoxin pair type II binding
CEG15_RS15685	COG4115	mRNA cleavage
CEG15_RS15710	COG0454	-acetyltransferase
CEG15_RS15755	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEG15_RS15785	COG1028	Short-chain dehydrogenase reductase Sdr
CEG15_RS15830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEG15_RS15880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEG15_RS15915	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CEG15_RS15985	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CEG15_RS15990	COG2944	sequence-specific DNA binding
CEG15_RS15995	COG0724	RNA recognition motif
CEG15_RS16000	COG0724	RNA recognition motif
CEG15_RS16075	COG2161	toxin-antitoxin pair type II binding
CEG15_RS16080	COG4115	mRNA cleavage
CEG15_RS16565	COG3040	lipid binding
CEG15_RS16570	COG5433	transposase activity
CEG15_RS16585	COG0456	acetyltransferase
CEG15_RS16595	COG0110	maltose O-acetyltransferase activity
CEG15_RS16715	COG0724	RNA recognition motif
CEG15_RS16730	COG0406	alpha-ribazole phosphatase activity
CEG15_RS16875	COG0346	lactoylglutathione lyase activity
CEG15_RS16890	COG0346	lactoylglutathione lyase activity
CEG15_RS16930	COG0583	DNA-binding transcription factor activity
CEG15_RS16995	COG0384	phenazine biosynthesis protein PhzF
CEG15_RS17010	COG1028	Short-chain dehydrogenase reductase Sdr
CEG15_RS17080	COG0023	Translation Initiation Factor
CEG15_RS17095	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEG15_RS17105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEG15_RS17105	COG1042	CoA-binding domain protein
CEG15_RS17105	COG0045	succinate-CoA ligase (ADP-forming) activity
CEG15_RS17110	COG0583	DNA-binding transcription factor activity
CEG15_RS17130	COG3140	Belongs to the UPF0181 family
CEG15_RS17145	COG0745	RESPONSE REGULATOR receiver
CEG15_RS17155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CEG15_RS17160	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CEG15_RS17175	COG3706	GGDEF domain
CEG15_RS17180	COG1278	Cold shock
CEG15_RS17190	COG0840	transmembrane signaling receptor activity
CEG15_RS17205	COG2501	S4 domain
CEG15_RS17210	COG0625	glutathione transferase activity
CEG15_RS17215	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEG15_RS17220	COG0488	(ABC) transporter
CEG15_RS17235	COG2050	protein possibly involved in aromatic compounds catabolism
CEG15_RS17245	COG2824	Alkylphosphonate utilization operon protein PhnA
CEG15_RS17255	COG0861	Integral membrane protein TerC family
CEG15_RS17260	COG0737	Belongs to the 5'-nucleotidase family
CEG15_RS17265	COG3593	DNA synthesis involved in DNA repair
CEG15_RS17275	COG0583	DNA-binding transcription factor activity
CEG15_RS17280	COG2116	formate transmembrane transporter activity
CEG15_RS17290	COG3104	oligopeptide transport
CEG15_RS17300	COG2188	Transcriptional regulator
CEG15_RS17305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEG15_RS17310	COG1011	Hydrolase
CEG15_RS17315	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CEG15_RS17325	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CEG15_RS17330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEG15_RS17335	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CEG15_RS17340	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEG15_RS17340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEG15_RS17345	COG0302	gtp cyclohydrolase
CEG15_RS17350	COG0303	'Molybdopterin
CEG15_RS17355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEG15_RS17360	COG2897	thiosulfate sulfurtransferase activity
CEG15_RS17380	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEG15_RS17395	COG0545	Peptidyl-prolyl cis-trans isomerase
CEG15_RS17400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEG15_RS17405	COG0840	transmembrane signaling receptor activity
CEG15_RS17410	COG2353	YceI-like domain
CEG15_RS17415	COG3038	cytochrome b561
CEG15_RS17425	COG5001	Diguanylate cyclase
CEG15_RS17425	COG2203	Gaf domain
CEG15_RS17425	COG3706	GGDEF domain
CEG15_RS17425	COG4251	negative regulation of phosphorylation
CEG15_RS17430	COG4172	Belongs to the ABC transporter superfamily
CEG15_RS17435	COG4239	(ABC) transporter, permease
CEG15_RS17440	COG4174	ABC transporter (Permease)
CEG15_RS17445	COG4166	transmembrane transport
CEG15_RS17460	COG0189	ligase activity
CEG15_RS17460	COG4067	protein conserved in archaea
CEG15_RS17470	COG0602	queuosine metabolic process
CEG15_RS17475	COG1328	CTP reductase activity
CEG15_RS17480	COG3706	GGDEF domain
CEG15_RS17525	COG3300	MHYT domain
CEG15_RS17525	COG5001	Diguanylate cyclase
CEG15_RS17530	COG4191	Histidine kinase
CEG15_RS17535	COG3852	Histidine kinase
CEG15_RS17560	COG2203	Gaf domain
CEG15_RS17560	COG3706	GGDEF domain
CEG15_RS17560	COG4251	negative regulation of phosphorylation
CEG15_RS17560	COG5001	Diguanylate cyclase
CEG15_RS17570	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CEG15_RS17575	COG4149	molybdate abc transporter
CEG15_RS17580	COG0725	ABC transporter, periplasmic molybdate-binding protein
CEG15_RS17585	COG1492	cobalamin metabolic process
CEG15_RS17590	COG3111	PFAM Bacterial OB fold (BOF) protein
CEG15_RS17605	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CEG15_RS17615	COG2207	Transcriptional regulator
CEG15_RS17620	COG1979	alcohol dehydrogenase
CEG15_RS17655	COG2205	protein histidine kinase activity
CEG15_RS17655	COG0784	Response regulator, receiver
CEG15_RS17655	COG2198	Histidine kinase
CEG15_RS17660	COG1879	ABC-type sugar transport system periplasmic component
CEG15_RS17665	COG1803	Methylglyoxal synthase
CEG15_RS17670	COG0210	DNA helicase
CEG15_RS17675	COG1289	transmembrane transporter activity
CEG15_RS17705	COG0784	Response regulator, receiver
CEG15_RS17705	COG5002	protein histidine kinase activity
CEG15_RS17720	COG2827	Endonuclease containing a URI domain
CEG15_RS17725	COG3132	Protein of unknown function, DUF480
CEG15_RS17745	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEG15_RS17750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEG15_RS17755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEG15_RS17760	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CEG15_RS17765	COG0247	lactate metabolic process
CEG15_RS17770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEG15_RS17775	COG3118	belongs to the thioredoxin family
CEG15_RS17795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEG15_RS17815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEG15_RS17855	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CEG15_RS17870	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CEG15_RS17880	COG0513	Belongs to the DEAD box helicase family
CEG15_RS17885	COG0814	amino acid
CEG15_RS17895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEG15_RS17900	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CEG15_RS17910	COG1984	allophanate hydrolase subunit 2
CEG15_RS17920	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CEG15_RS17925	COG4181	ATPase activity
CEG15_RS17935	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEG15_RS17940	COG5001	Diguanylate cyclase
CEG15_RS17940	COG1716	ATPase activity
CEG15_RS17950	COG0484	heat shock protein binding
CEG15_RS17970	COG0784	Response regulator, receiver
CEG15_RS17970	COG3437	response regulator, receiver
CEG15_RS17985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEG15_RS17990	COG3300	MHYT domain
CEG15_RS17990	COG5001	Diguanylate cyclase
CEG15_RS18010	COG0010	Belongs to the arginase family
CEG15_RS18015	COG1166	arginine decarboxylase activity
CEG15_RS18030	COG4176	ABC-type proline glycine betaine transport system permease component
CEG15_RS18035	COG2113	Glycine betaine
CEG15_RS18060	COG0527	aspartate kinase activity
CEG15_RS18065	COG0662	Cupin 2, conserved barrel domain protein
CEG15_RS18070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CEG15_RS18075	COG0456	acetyltransferase
CEG15_RS18085	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEG15_RS18090	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CEG15_RS18125	COG0366	Alpha amylase catalytic
CEG15_RS18145	COG0714	Associated with various cellular activities
CEG15_RS18165	COG2304	oxidoreductase activity
CEG15_RS18180	COG3706	GGDEF domain
CEG15_RS18205	COG1368	sulfuric ester hydrolase activity
CEG15_RS18215	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEG15_RS18220	COG3227	Zinc metalloprotease (Elastase)
CEG15_RS18235	COG2258	MOSC domain
CEG15_RS18265	COG1063	alcohol dehydrogenase
CEG15_RS18270	COG0156	8-amino-7-oxononanoate synthase activity
CEG15_RS18280	COG0346	lactoylglutathione lyase activity
CEG15_RS18295	COG2197	response regulator
CEG15_RS18300	COG3851	Histidine kinase
CEG15_RS18305	COG2271	Major facilitator Superfamily
CEG15_RS18315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CEG15_RS18340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEG15_RS18345	COG0640	Transcriptional regulator
CEG15_RS18350	COG0798	PFAM Bile acid sodium symporter
CEG15_RS18355	COG0640	Transcriptional regulator
CEG15_RS18360	COG0659	secondary active sulfate transmembrane transporter activity
CEG15_RS18365	COG0589	response to stress
CEG15_RS18390	COG4977	sequence-specific DNA binding
CEG15_RS18390	COG1917	Cupin 2, conserved barrel domain protein
CEG15_RS18395	COG4771	TonB-dependent receptor
CEG15_RS18400	COG2814	Major facilitator Superfamily
CEG15_RS18405	COG2226	methyltransferase
CEG15_RS18405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEG15_RS18405	COG3433	isochorismatase activity
CEG15_RS18430	COG1021	2,3-dihydroxybenzoate-AMP ligase
CEG15_RS18435	COG1132	(ABC) transporter
CEG15_RS18440	COG1132	(ABC) transporter
CEG15_RS18470	COG0542	response to heat
CEG15_RS18515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEG15_RS18525	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CEG15_RS18530	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CEG15_RS18535	COG2204	response regulator
CEG15_RS18595	COG0516	GMP reductase activity
CEG15_RS18600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEG15_RS18625	COG1278	Cold shock
CEG15_RS18630	COG4681	YaeQ
CEG15_RS18635	COG1017	nitric oxide dioxygenase activity
CEG15_RS18635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEG15_RS18640	COG3604	Transcriptional regulator
CEG15_RS18650	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEG15_RS18655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEG15_RS18660	COG3217	Mosc domain protein beta barrel domain protein
CEG15_RS18660	COG0633	Ferredoxin
CEG15_RS18665	COG0418	dihydroorotase activity
CEG15_RS18670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEG15_RS18675	COG2354	Protein conserved in bacteria
CEG15_RS18700	COG2199	diguanylate cyclase activity
CEG15_RS18705	COG1349	DNA-binding transcription factor activity
CEG15_RS18730	COG3833	ABC-type maltose transport systems, permease component
CEG15_RS18735	COG1175	transmembrane transport
CEG15_RS18750	COG3842	ATPase activity
CEG15_RS18760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEG15_RS18765	COG0835	chemotaxis
CEG15_RS18765	COG0784	Response regulator, receiver
CEG15_RS18770	COG2315	Protein conserved in bacteria
CEG15_RS18775	COG3706	GGDEF domain
CEG15_RS18810	COG5001	Diguanylate cyclase
CEG15_RS18820	COG1741	Belongs to the pirin family
CEG15_RS18830	COG3123	guanosine phosphorylase activity
CEG15_RS18840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEG15_RS18850	COG0765	amino acid transport
CEG15_RS18855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEG15_RS18860	COG0765	amino acid transport
CEG15_RS18865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEG15_RS18880	COG0179	Fumarylacetoacetate (FAA) hydrolase
CEG15_RS18890	COG0697	spore germination
CEG15_RS18910	COG2814	Major facilitator Superfamily
CEG15_RS18915	COG0583	DNA-binding transcription factor activity
CEG15_RS18920	COG5001	Diguanylate cyclase
CEG15_RS18925	COG0739	heme binding
CEG15_RS18935	COG0659	secondary active sulfate transmembrane transporter activity
CEG15_RS18940	COG3314	Sporulation integral membrane protein YlbJ
CEG15_RS18955	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEG15_RS18960	COG0581	inorganic phosphate transmembrane transporter activity
CEG15_RS18965	COG0573	inorganic phosphate transmembrane transporter activity
CEG15_RS18970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEG15_RS18980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEG15_RS18985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEG15_RS19005	COG3047	cAMP biosynthetic process
CEG15_RS19020	COG2271	Major facilitator Superfamily
CEG15_RS19025	COG0584	glycerophosphoryl diester phosphodiesterase
CEG15_RS19035	COG3527	Alpha-acetolactate decarboxylase
CEG15_RS19050	COG0488	(ABC) transporter
CEG15_RS19060	COG2207	Transcriptional regulator
CEG15_RS19060	COG3708	Transcriptional regulator
CEG15_RS19065	COG0583	DNA-binding transcription factor activity
CEG15_RS19070	COG1620	l-lactate permease
CEG15_RS19090	COG1881	PFAM PEBP family protein
CEG15_RS19095	COG3122	Protein conserved in bacteria
CEG15_RS19105	COG3568	Endonuclease Exonuclease Phosphatase
CEG15_RS19120	COG0840	transmembrane signaling receptor activity
CEG15_RS19135	COG1609	Transcriptional regulator
CEG15_RS19145	COG3842	ATPase activity
CEG15_RS19150	COG0395	ABC-type sugar transport system, permease component
CEG15_RS19155	COG1175	transmembrane transport
CEG15_RS19165	COG1609	Transcriptional regulator
CEG15_RS19170	COG4580	involved in the transport of maltose and maltodextrins
CEG15_RS19190	COG2211	Major facilitator Superfamily
CEG15_RS19200	COG1067	ATP-dependent peptidase activity
CEG15_RS19210	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEG15_RS19215	COG0363	glucosamine-6-phosphate deaminase activity
CEG15_RS19225	COG0583	DNA-binding transcription factor activity
CEG15_RS19240	COG1609	Transcriptional regulator
CEG15_RS19245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEG15_RS19250	COG1879	ABC-type sugar transport system periplasmic component
CEG15_RS19255	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEG15_RS19260	COG1129	ABC transporter
CEG15_RS19265	COG1869	D-ribose catabolic process
CEG15_RS19280	COG3409	Peptidoglycan-binding domain 1 protein
CEG15_RS19280	COG3501	Rhs element vgr protein
CEG15_RS19290	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CEG15_RS19295	COG1640	4-alpha-glucanotransferase
CEG15_RS19300	COG0058	SHG alpha-glucan phosphorylase activity
CEG15_RS19305	COG2909	trisaccharide binding
CEG15_RS19330	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CEG15_RS19350	COG0840	transmembrane signaling receptor activity
CEG15_RS19385	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CEG15_RS19395	COG0259	pyridoxamine-phosphate oxidase activity
CEG15_RS19445	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CEG15_RS19450	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CEG15_RS19455	COG0840	transmembrane signaling receptor activity
CEG15_RS19465	COG0835	chemotaxis
CEG15_RS19470	COG0643	Histidine kinase
CEG15_RS19470	COG2198	Histidine kinase
CEG15_RS19475	COG0745	RESPONSE REGULATOR receiver
CEG15_RS19485	COG1444	tRNA N-acetyltransferase activity
CEG15_RS19490	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine