locus-tag	class	description
CK207_RS00005	COG0445	tRNA wobble uridine modification
CK207_RS00015	COG1192	Involved in chromosome partitioning
CK207_RS00020	COG1475	DNA binding
CK207_RS00025	COG3312	ion transport
CK207_RS00040	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CK207_RS00045	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CK207_RS00050	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CK207_RS00055	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CK207_RS00060	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CK207_RS00065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CK207_RS00075	COG2814	Major facilitator Superfamily
CK207_RS00080	COG0583	DNA-binding transcription factor activity
CK207_RS00085	COG0183	Belongs to the thiolase family
CK207_RS00095	COG1739	Uncharacterized protein family UPF0029
CK207_RS00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CK207_RS00105	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CK207_RS00150	COG0352	thiamine-phosphate diphosphorylase activity
CK207_RS00160	COG2104	thiamine diphosphate biosynthetic process
CK207_RS00165	COG2022	thiamine diphosphate biosynthetic process
CK207_RS00170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CK207_RS00175	COG0006	proline dipeptidase activity
CK207_RS00175	COG0006	proline dipeptidase activity
CK207_RS00195	COG1522	sequence-specific DNA binding
CK207_RS00200	COG0742	ribosomal rna small subunit methyltransferase
CK207_RS00215	COG0589	response to stress
CK207_RS00220	COG1528	Iron-storage protein
CK207_RS00235	COG2081	HI0933 family
CK207_RS00270	COG0784	Response regulator, receiver
CK207_RS00270	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CK207_RS00290	COG0606	chelatase, subunit chli
CK207_RS00300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CK207_RS00305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CK207_RS00310	COG3385	transposase activity
CK207_RS00325	COG3084	Protein conserved in bacteria
CK207_RS00335	COG1272	protein, Hemolysin III
CK207_RS00345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CK207_RS00350	COG0569	domain protein
CK207_RS00355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CK207_RS00355	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CK207_RS00360	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CK207_RS00365	COG0242	peptide deformylase activity
CK207_RS00370	COG1652	LysM domain
CK207_RS00375	COG0758	DNA mediated transformation
CK207_RS00380	COG2922	Belongs to the Smg family
CK207_RS00385	COG0551	DNA topoisomerase type I activity
CK207_RS00390	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CK207_RS00395	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CK207_RS00400	COG0009	L-threonylcarbamoyladenylate synthase
CK207_RS00405	COG0408	coproporphyrinogen oxidase activity
CK207_RS00410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CK207_RS00420	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CK207_RS00455	COG3071	HemY protein
CK207_RS00460	COG2959	enzyme of heme biosynthesis
CK207_RS00465	COG1587	Uroporphyrinogen-III synthase
CK207_RS00490	COG0019	diaminopimelate decarboxylase activity
CK207_RS00495	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CK207_RS00505	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CK207_RS00510	COG1011	Hydrolase
CK207_RS00515	COG3148	PFAM DTW domain containing protein
CK207_RS00525	COG0561	phosphatase activity
CK207_RS00530	COG2267	carboxylic ester hydrolase activity
CK207_RS00535	COG1280	lysine exporter protein (LysE YggA)
CK207_RS00540	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CK207_RS00545	COG0783	Belongs to the Dps family
CK207_RS00575	COG2095	MarC family integral membrane protein
CK207_RS00590	COG2433	Pfam Transposase IS66
CK207_RS00605	COG4372	Transposase
CK207_RS00615	COG2433	Pfam Transposase IS66
CK207_RS00650	COG3335	DDE superfamily endonuclease
CK207_RS00660	COG2095	MarC family integral membrane protein
CK207_RS00670	COG0742	ribosomal rna small subunit methyltransferase
CK207_RS00675	COG0552	protein localization to endoplasmic reticulum
CK207_RS00680	COG2884	Cell division ATP-binding protein ftsE
CK207_RS00685	COG2177	Part of the ABC transporter FtsEX involved in
CK207_RS00690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CK207_RS00700	COG0705	Rhomboid family
CK207_RS00705	COG1580	Controls the rotational direction of flagella during chemotaxis
CK207_RS00710	COG3161	chorismate lyase activity
CK207_RS00720	COG2937	Belongs to the GPAT DAPAT family
CK207_RS00725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CK207_RS00735	COG0534	Mate efflux family protein
CK207_RS00740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK207_RS00760	COG3250	beta-galactosidase activity
CK207_RS00800	COG0328	RNA-DNA hybrid ribonuclease activity
CK207_RS00845	COG2003	Belongs to the UPF0758 family
CK207_RS00870	COG2433	Pfam Transposase IS66
CK207_RS00895	COG3335	DDE superfamily endonuclease
CK207_RS00910	COG2433	Pfam Transposase IS66
CK207_RS00920	COG0210	DNA helicase
CK207_RS00940	COG4206	TonB-dependent receptor
CK207_RS00950	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CK207_RS00990	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CK207_RS00995	COG5001	Diguanylate cyclase
CK207_RS00995	COG3300	MHYT domain
CK207_RS01005	COG3852	Histidine kinase
CK207_RS01015	COG0174	glutamine synthetase
CK207_RS01020	COG1217	gtp-binding protein TYPA
CK207_RS01025	COG1295	ribonuclease BN
CK207_RS01030	COG1490	D-aminoacyl-tRNA deacylase activity
CK207_RS01035	COG0456	acetyltransferase
CK207_RS01045	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CK207_RS01050	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CK207_RS01055	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CK207_RS01060	COG3031	protein transport across the cell outer membrane
CK207_RS01070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CK207_RS01075	COG1459	type II secretion system
CK207_RS01080	COG2165	general secretion pathway protein
CK207_RS01085	COG2165	general secretion pathway protein
CK207_RS01090	COG2165	general secretion pathway protein
CK207_RS01095	COG4795	General secretion pathway protein
CK207_RS01100	COG3156	type II secretion system protein K
CK207_RS01105	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CK207_RS01110	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CK207_RS01120	COG1218	3'(2'),5'-bisphosphate nucleotidase
CK207_RS01125	COG0494	nUDIX hydrolase
CK207_RS01130	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CK207_RS01130	COG0316	Belongs to the HesB IscA family
CK207_RS01135	COG1040	competence protein
CK207_RS01140	COG0596	Alpha beta hydrolase
CK207_RS01150	COG2183	response to ionizing radiation
CK207_RS01155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CK207_RS01175	COG0583	DNA-binding transcription factor activity
CK207_RS01205	COG2233	PERMEase
CK207_RS01215	COG2233	PERMEase
CK207_RS01220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CK207_RS01225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CK207_RS01230	COG1758	RNA polymerase activity
CK207_RS01235	COG0194	GDP metabolic process
CK207_RS01240	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CK207_RS01245	COG0248	Ppx GppA phosphatase
CK207_RS01255	COG3118	belongs to the thioredoxin family
CK207_RS01270	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CK207_RS01355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK207_RS01365	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CK207_RS01370	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CK207_RS01370	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CK207_RS01375	COG1072	(Pantothenic acid kinase))
CK207_RS01400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CK207_RS01405	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CK207_RS01410	COG0250	Participates in transcription elongation, termination and antitermination
CK207_RS01425	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CK207_RS01430	COG0222	ribosome binding
CK207_RS01435	COG0085	RNA polymerase activity
CK207_RS01440	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CK207_RS01445	COG3385	transposase activity
CK207_RS01450	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CK207_RS01455	COG2816	NAD+ diphosphatase activity
CK207_RS01460	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CK207_RS01475	COG4942	peptidase
CK207_RS01480	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CK207_RS01495	COG0490	domain, Protein
CK207_RS01495	COG0471	metal ion transport
CK207_RS01505	COG1162	GTPase activity
CK207_RS01510	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CK207_RS01565	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CK207_RS01570	COG0802	atpase or kinase
CK207_RS01575	COG0860	N-Acetylmuramoyl-L-alanine amidase
CK207_RS01580	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CK207_RS01585	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CK207_RS01595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CK207_RS01600	COG0330	HflC and HflK could
CK207_RS01605	COG0330	HflC and HflK could
CK207_RS01610	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CK207_RS01625	COG0545	Peptidyl-prolyl cis-trans isomerase
CK207_RS01630	COG2964	Protein conserved in bacteria
CK207_RS01635	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CK207_RS01640	COG2923	Belongs to the DsrF TusC family
CK207_RS01655	COG0049	tRNA binding
CK207_RS01660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CK207_RS01665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CK207_RS01670	COG0360	Binds together with S18 to 16S ribosomal RNA
CK207_RS01675	COG2965	DNA replication, synthesis of RNA primer
CK207_RS01685	COG0359	binds to the 23S rRNA
CK207_RS01700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CK207_RS01705	COG0166	Belongs to the GPI family
CK207_RS01715	COG0735	belongs to the Fur family
CK207_RS01720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK207_RS01740	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CK207_RS01750	COG0175	sulfate reduction
CK207_RS01835	COG1410	methionine synthase
CK207_RS01835	COG0646	methionine synthase
CK207_RS01840	COG0527	aspartate kinase activity
CK207_RS01845	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CK207_RS01860	COG2239	Acts as a magnesium transporter
CK207_RS01865	COG2433	Pfam Transposase IS66
CK207_RS01885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CK207_RS01900	COG0629	single-stranded DNA binding
CK207_RS01905	COG2199	diguanylate cyclase activity
CK207_RS01905	COG2200	EAL domain
CK207_RS01930	COG3267	Type II secretory pathway component ExeA
CK207_RS01930	COG3409	Peptidoglycan-binding domain 1 protein
CK207_RS01940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CK207_RS01945	COG1459	type II secretion system
CK207_RS01955	COG2165	general secretion pathway protein
CK207_RS01960	COG2165	general secretion pathway protein
CK207_RS01990	COG1077	Cell shape determining protein MreB Mrl
CK207_RS01995	COG1792	Involved in formation and maintenance of cell shape
CK207_RS02000	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CK207_RS02005	COG0424	maF-like protein
CK207_RS02015	COG3164	Protein of unknown function
CK207_RS02020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CK207_RS02025	COG0312	modulator of DNA gyrase
CK207_RS02030	COG2235	arginine
CK207_RS02050	COG0589	response to stress
CK207_RS02060	COG2358	TRAP transporter, solute receptor (TAXI family
CK207_RS02070	COG1438	arginine binding
CK207_RS02080	COG0531	amino acid
CK207_RS02085	COG3385	transposase activity
CK207_RS02090	COG0142	geranyltranstransferase activity
CK207_RS02100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CK207_RS02105	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CK207_RS02110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CK207_RS02115	COG2966	Psort location CytoplasmicMembrane, score
CK207_RS02120	COG3610	response to peptide
CK207_RS02135	COG2967	ApaG domain
CK207_RS02140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CK207_RS02145	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CK207_RS02150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK207_RS02155	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CK207_RS02160	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CK207_RS02210	COG0741	lytic transglycosylase activity
CK207_RS02215	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CK207_RS02230	COG2066	Belongs to the glutaminase family
CK207_RS02235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CK207_RS02240	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CK207_RS02255	COG0762	integral membrane protein
CK207_RS02260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CK207_RS02265	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CK207_RS02280	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CK207_RS02285	COG1678	Uncharacterized ACR, COG1678
CK207_RS02295	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CK207_RS02300	COG2356	endonuclease I
CK207_RS02305	COG3091	SprT-like family
CK207_RS02310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CK207_RS02315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CK207_RS02320	COG0583	DNA-binding transcription factor activity
CK207_RS02325	COG4771	TonB-dependent receptor
CK207_RS02330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CK207_RS02335	COG0126	phosphoglycerate kinase activity
CK207_RS02345	COG0191	fructose-bisphosphate aldolase activity
CK207_RS02350	COG0668	transmembrane transport
CK207_RS02370	COG3706	GGDEF domain
CK207_RS02375	COG3385	transposase activity
CK207_RS02385	COG1349	DNA-binding transcription factor activity
CK207_RS02410	COG4251	negative regulation of phosphorylation
CK207_RS02420	COG3335	DDE superfamily endonuclease
CK207_RS02460	COG2433	Pfam Transposase IS66
CK207_RS02465	COG4372	Transposase
CK207_RS02535	COG0583	DNA-binding transcription factor activity
CK207_RS02540	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CK207_RS02560	COG3501	Rhs element vgr protein
CK207_RS02610	COG0358	DNA primase activity
CK207_RS02615	COG1610	YqeY-like protein
CK207_RS02620	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CK207_RS02625	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CK207_RS02635	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CK207_RS02640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CK207_RS02645	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CK207_RS02650	COG1968	undecaprenyl-diphosphatase activity
CK207_RS02655	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CK207_RS02660	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CK207_RS02665	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CK207_RS02670	COG0585	pseudouridine synthase activity
CK207_RS02675	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CK207_RS02680	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CK207_RS02685	COG4942	peptidase
CK207_RS02685	COG1388	LysM domain
CK207_RS02695	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CK207_RS02705	COG4150	thiosulfate binding
CK207_RS02715	COG4208	sulfate ABC transporter
CK207_RS02720	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CK207_RS02725	COG1546	Belongs to the CinA family
CK207_RS02730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CK207_RS02735	COG2137	regulation of response to DNA damage stimulus
CK207_RS02740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CK207_RS02745	COG0527	aspartate kinase activity
CK207_RS02750	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CK207_RS02795	COG3630	sodium ion export across plasma membrane
CK207_RS02800	COG5016	pyruvate
CK207_RS02800	COG0511	ligase activity, forming carbon-carbon bonds
CK207_RS02805	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CK207_RS02815	COG1238	metal cluster binding
CK207_RS02820	COG0612	Peptidase, M16
CK207_RS02830	COG1854	S-ribosylhomocysteine lyase activity
CK207_RS02835	COG4536	flavin adenine dinucleotide binding
CK207_RS02840	COG4137	Cytochrome C assembly protein
CK207_RS02845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CK207_RS02850	COG0228	four-way junction DNA binding
CK207_RS02855	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CK207_RS02860	COG0336	Belongs to the RNA methyltransferase TrmD family
CK207_RS02865	COG0335	large ribosomal subunit rRNA binding
CK207_RS02875	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CK207_RS02880	COG0237	dephospho-CoA kinase activity
CK207_RS02890	COG1459	type II secretion system
CK207_RS02895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CK207_RS02900	COG4969	Belongs to the N-Me-Phe pilin family
CK207_RS02905	COG0157	Belongs to the NadC ModD family
CK207_RS02915	COG0716	FMN binding
CK207_RS02920	COG4974	Belongs to the 'phage' integrase family
CK207_RS02925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CK207_RS02930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CK207_RS02935	COG2186	Transcriptional regulator
CK207_RS02940	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CK207_RS02945	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK207_RS02950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK207_RS02965	COG0288	reversible hydration of carbon dioxide
CK207_RS02970	COG0659	secondary active sulfate transmembrane transporter activity
CK207_RS02975	COG1131	(ABC) transporter
CK207_RS02995	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CK207_RS03020	COG4974	Belongs to the 'phage' integrase family
CK207_RS03040	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CK207_RS03050	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CK207_RS03060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CK207_RS03065	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CK207_RS03070	COG1489	DNA binding
CK207_RS03075	COG1643	Atp-dependent helicase
CK207_RS03080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CK207_RS03085	COG1752	Esterase of the alpha-beta hydrolase superfamily
CK207_RS03090	COG1049	propionate catabolic process, 2-methylcitrate cycle
CK207_RS03095	COG1929	Belongs to the glycerate kinase type-1 family
CK207_RS03100	COG2610	gluconate transmembrane transporter activity
CK207_RS03105	COG3835	regulator
CK207_RS03110	COG3112	Uncharacterised protein family (UPF0231)
CK207_RS03120	COG0004	ammonium transporteR
CK207_RS03125	COG1840	ABC-type Fe3 transport system, periplasmic component
CK207_RS03140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CK207_RS03155	COG2971	BadF BadG BcrA BcrD
CK207_RS03165	COG4608	Belongs to the ABC transporter superfamily
CK207_RS03170	COG0444	Belongs to the ABC transporter superfamily
CK207_RS03175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK207_RS03185	COG0747	negative chemotaxis
CK207_RS03190	COG2205	protein histidine kinase activity
CK207_RS03190	COG0784	Response regulator, receiver
CK207_RS03200	COG0628	permease
CK207_RS03205	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CK207_RS03210	COG0316	Belongs to the HesB IscA family
CK207_RS03225	COG0739	heme binding
CK207_RS03230	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CK207_RS03240	COG2239	Acts as a magnesium transporter
CK207_RS03245	COG2027	D-alanyl-D-alanine carboxypeptidase
CK207_RS03250	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CK207_RS03255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CK207_RS03260	COG1534	Rna-binding protein
CK207_RS03265	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CK207_RS03270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CK207_RS03275	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CK207_RS03280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CK207_RS03285	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CK207_RS03300	COG0779	Required for maturation of 30S ribosomal subunits
CK207_RS03305	COG0195	Participates in both transcription termination and antitermination
CK207_RS03320	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CK207_RS03325	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CK207_RS03340	COG1846	Transcriptional regulator
CK207_RS03350	COG0826	peptidase U32
CK207_RS03355	COG0826	peptidase U32
CK207_RS03365	COG3154	lipid carrier protein
CK207_RS03370	COG3153	acetyltransferase
CK207_RS03395	COG0513	Belongs to the DEAD box helicase family
CK207_RS03400	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CK207_RS03415	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CK207_RS03420	COG2204	response regulator
CK207_RS03430	COG0667	Aldo Keto reductase
CK207_RS03440	COG0494	nUDIX hydrolase
CK207_RS03445	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CK207_RS03450	COG0730	response to heat
CK207_RS03460	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CK207_RS03465	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CK207_RS03490	COG3550	peptidyl-serine autophosphorylation
CK207_RS03530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CK207_RS03550	COG2433	Pfam Transposase IS66
CK207_RS03565	COG2433	Pfam Transposase IS66
CK207_RS03585	COG4974	Belongs to the 'phage' integrase family
CK207_RS03590	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CK207_RS03595	COG1283	sodium-dependent phosphate transmembrane transporter activity
CK207_RS03600	COG0583	DNA-binding transcription factor activity
CK207_RS03605	COG0640	Transcriptional regulator
CK207_RS03610	COG0268	Binds directly to 16S ribosomal RNA
CK207_RS03615	COG0728	peptidoglycan biosynthetic process
CK207_RS03620	COG0196	riboflavin kinase activity
CK207_RS03630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CK207_RS03635	COG1047	Peptidyl-prolyl cis-trans
CK207_RS03640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CK207_RS03645	COG1966	Carbon starvation protein
CK207_RS03660	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CK207_RS03665	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CK207_RS03675	COG3279	Response regulator of the LytR AlgR family
CK207_RS03680	COG3275	phosphorelay sensor kinase activity
CK207_RS03685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CK207_RS03690	COG0287	Prephenate dehydrogenase
CK207_RS03690	COG1605	Chorismate mutase
CK207_RS03700	COG0488	(ABC) transporter
CK207_RS03710	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CK207_RS03715	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CK207_RS03720	COG5001	Diguanylate cyclase
CK207_RS03725	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CK207_RS03730	COG1605	Chorismate mutase
CK207_RS03730	COG0077	Prephenate dehydratase
CK207_RS03735	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CK207_RS03740	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CK207_RS03745	COG0564	pseudouridine synthase activity
CK207_RS03750	COG1496	oxidoreductase activity
CK207_RS03755	COG0542	response to heat
CK207_RS03795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CK207_RS03800	COG0826	peptidase U32
CK207_RS03810	COG0745	RESPONSE REGULATOR receiver
CK207_RS03815	COG5002	protein histidine kinase activity
CK207_RS03825	COG0248	Ppx GppA phosphatase
CK207_RS03830	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CK207_RS03840	COG0581	inorganic phosphate transmembrane transporter activity
CK207_RS03845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CK207_RS03850	COG0704	Plays a role in the regulation of phosphate uptake
CK207_RS03855	COG3142	Participates in the control of copper homeostasis
CK207_RS03860	COG0450	alkyl hydroperoxide reductase
CK207_RS03865	COG0583	DNA-binding transcription factor activity
CK207_RS03870	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CK207_RS03880	COG0517	IMP dehydrogenase activity
CK207_RS03890	COG0343	queuine tRNA-ribosyltransferase activity
CK207_RS03895	COG1862	Preprotein translocase
CK207_RS03900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK207_RS03905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK207_RS03910	COG0483	inositol monophosphate 1-phosphatase activity
CK207_RS03915	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CK207_RS03920	COG1959	2 iron, 2 sulfur cluster binding
CK207_RS03930	COG0822	iron-sulfur transferase activity
CK207_RS03935	COG0316	Belongs to the HesB IscA family
CK207_RS03945	COG0443	Heat shock 70 kDa protein
CK207_RS03950	COG0633	Ferredoxin
CK207_RS03955	COG2975	iron-sulfur cluster assembly
CK207_RS03960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CK207_RS03975	COG1426	Protein conserved in bacteria
CK207_RS03980	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CK207_RS03985	COG0124	histidyl-tRNA synthetase
CK207_RS03990	COG2976	Protein conserved in bacteria
CK207_RS03995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CK207_RS04000	COG1160	GTP binding
CK207_RS04020	COG0517	IMP dehydrogenase activity
CK207_RS04020	COG0516	GMP reductase activity
CK207_RS04025	COG0519	Catalyzes the synthesis of GMP from XMP
CK207_RS04025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CK207_RS04030	COG0351	phosphomethylpyrimidine kinase
CK207_RS04040	COG1584	GPR1 FUN34 yaaH family protein
CK207_RS04045	COG1115	amino acid carrier protein
CK207_RS04070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_RS04070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_RS04085	COG3964	amidohydrolase
CK207_RS04115	COG0556	nucleotide-excision repair
CK207_RS04150	COG2433	Pfam Transposase IS66
CK207_RS04210	COG2003	Belongs to the UPF0758 family
CK207_RS04255	COG2433	Pfam Transposase IS66
CK207_RS04270	COG2801	Transposase and inactivated derivatives
CK207_RS04275	COG0582	viral genome integration into host DNA
CK207_RS04310	COG2003	Belongs to the UPF0758 family
CK207_RS04320	COG4409	exo-alpha-(2->6)-sialidase activity
CK207_RS04325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CK207_RS04330	COG1940	carbohydrate kinase activity
CK207_RS04345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CK207_RS04350	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CK207_RS04355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CK207_RS04360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CK207_RS04365	COG1737	Transcriptional regulator
CK207_RS04370	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CK207_RS04375	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CK207_RS04390	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_RS04395	COG3716	PTS system mannose fructose sorbose family IID component
CK207_RS04400	COG3715	PTS system
CK207_RS04405	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK207_RS04410	COG2222	sugar isomerase
CK207_RS04420	COG1349	DNA-binding transcription factor activity
CK207_RS04425	COG1349	DNA-binding transcription factor activity
CK207_RS04440	COG2003	Belongs to the UPF0758 family
CK207_RS04490	COG1715	Restriction endonuclease
CK207_RS04495	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CK207_RS04500	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CK207_RS04505	COG0732	type I restriction modification DNA specificity domain
CK207_RS04510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CK207_RS04530	COG2433	Pfam Transposase IS66
CK207_RS04540	COG0582	viral genome integration into host DNA
CK207_RS04555	COG2433	Pfam Transposase IS66
CK207_RS04560	COG0582	viral genome integration into host DNA
CK207_RS04575	COG2867	negative regulation of translational initiation
CK207_RS04580	COG2914	Belongs to the UPF0125 (RnfH) family
CK207_RS04585	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CK207_RS04590	COG0497	DNA recombination
CK207_RS04595	COG3033	Beta-eliminating lyase
CK207_RS04600	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CK207_RS04605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CK207_RS04610	COG0443	Heat shock 70 kDa protein
CK207_RS04615	COG0484	heat shock protein binding
CK207_RS04650	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CK207_RS04660	COG0583	DNA-binding transcription factor activity
CK207_RS04665	COG0590	tRNA wobble adenosine to inosine editing
CK207_RS04670	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CK207_RS04695	COG2979	Protein of unknown function (DUF533)
CK207_RS04700	COG0442	prolyl-tRNA aminoacylation
CK207_RS04705	COG1720	tRNA m6t6A37 methyltransferase activity
CK207_RS04710	COG0254	rRNA binding
CK207_RS04715	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CK207_RS04745	COG3098	single-species biofilm formation
CK207_RS04750	COG0564	pseudouridine synthase activity
CK207_RS04755	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CK207_RS04760	COG0142	geranyltranstransferase activity
CK207_RS04765	COG1722	exodeoxyribonuclease VII activity
CK207_RS04770	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CK207_RS04780	COG0301	tRNA thio-modification
CK207_RS04780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CK207_RS04785	COG0583	DNA-binding transcription factor activity
CK207_RS04790	COG2363	Small membrane protein
CK207_RS04795	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CK207_RS04800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CK207_RS04805	COG1611	Belongs to the LOG family
CK207_RS04830	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CK207_RS04835	COG1464	Belongs to the NlpA lipoprotein family
CK207_RS04840	COG2011	ABC-type metal ion transport system permease component
CK207_RS04845	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CK207_RS04850	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CK207_RS04865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK207_RS04865	COG1263	PTS System
CK207_RS04870	COG0366	Alpha amylase catalytic
CK207_RS04875	COG0745	RESPONSE REGULATOR receiver
CK207_RS04880	COG2205	protein histidine kinase activity
CK207_RS04915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK207_RS04920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK207_RS04925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CK207_RS04930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CK207_RS04935	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CK207_RS04950	COG1215	transferase activity, transferring glycosyl groups
CK207_RS04955	COG0438	transferase activity, transferring glycosyl groups
CK207_RS04975	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CK207_RS05010	COG0489	protein tyrosine kinase activity
CK207_RS05015	COG1596	polysaccharide export
CK207_RS05045	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CK207_RS05050	COG0321	lipoyl(octanoyl) transferase activity
CK207_RS05055	COG2921	Belongs to the UPF0250 family
CK207_RS05060	COG1686	Belongs to the peptidase S11 family
CK207_RS05065	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CK207_RS05070	COG0772	Belongs to the SEDS family
CK207_RS05075	COG0768	penicillin binding
CK207_RS05080	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CK207_RS05085	COG0799	negative regulation of ribosome biogenesis
CK207_RS05090	COG1466	dna polymerase III delta subunit
CK207_RS05095	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CK207_RS05100	COG0495	leucyl-tRNA aminoacylation
CK207_RS05105	COG2888	peptidyl-tyrosine sulfation
CK207_RS05110	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CK207_RS05115	COG4535	Mg2 and Co2 transporter CorC
CK207_RS05120	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CK207_RS05125	COG1702	phosphate starvation-inducible protein PhoH
CK207_RS05130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CK207_RS05135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK207_RS05140	COG2190	(PTS) system
CK207_RS05145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CK207_RS05150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_RS05155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CK207_RS05160	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CK207_RS05165	COG3115	cell septum assembly
CK207_RS05170	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CK207_RS05185	COG3335	DDE superfamily endonuclease
CK207_RS05190	COG0789	Transcriptional regulator
CK207_RS05200	COG0330	HflC and HflK could
CK207_RS05205	COG3118	belongs to the thioredoxin family
CK207_RS05210	COG1090	epimerase
CK207_RS05215	COG0622	Phosphoesterase
CK207_RS05230	COG3710	Transcriptional regulator
CK207_RS05235	COG0326	Molecular chaperone. Has ATPase activity
CK207_RS05245	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CK207_RS05250	COG3104	oligopeptide transport
CK207_RS05255	COG2433	Pfam Transposase IS66
CK207_RS05270	COG3104	oligopeptide transport
CK207_RS05275	COG3385	transposase activity
CK207_RS05285	COG0367	asparagine synthase
CK207_RS05290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CK207_RS05290	COG4651	solute:proton antiporter activity
CK207_RS05295	COG1846	Transcriptional regulator
CK207_RS05295	COG1940	carbohydrate kinase activity
CK207_RS05300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CK207_RS05305	COG1263	PTS System
CK207_RS05305	COG2190	(PTS) system
CK207_RS05305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK207_RS05310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CK207_RS05320	COG0101	tRNA pseudouridine synthase activity
CK207_RS05325	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CK207_RS05330	COG0285	dihydrofolate synthase activity
CK207_RS05335	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CK207_RS05340	COG1286	toxin biosynthetic process
CK207_RS05345	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CK207_RS05350	COG2056	Na+-H+ antiporter family
CK207_RS05355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CK207_RS05365	COG0346	lactoylglutathione lyase activity
CK207_RS05375	COG2433	Pfam Transposase IS66
CK207_RS05400	COG1132	(ABC) transporter
CK207_RS05440	COG2433	Pfam Transposase IS66
CK207_RS05475	COG2433	Pfam Transposase IS66
CK207_RS05495	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CK207_RS05500	COG4660	Part of a membrane complex involved in electron transport
CK207_RS05505	COG4659	FMN binding
CK207_RS05510	COG4658	electron transport chain
CK207_RS05515	COG4656	Part of a membrane complex involved in electron transport
CK207_RS05520	COG2878	Part of a membrane complex involved in electron transport
CK207_RS05525	COG4657	Part of a membrane complex involved in electron transport
CK207_RS05535	COG1629	transport
CK207_RS05535	COG4774	siderophore transport
CK207_RS05540	COG2382	esterase
CK207_RS05560	COG3433	isochorismatase activity
CK207_RS05560	COG1535	isochorismatase
CK207_RS05565	COG1021	2,3-dihydroxybenzoate-AMP ligase
CK207_RS05570	COG1169	isochorismate synthase
CK207_RS05575	COG1028	Short-chain dehydrogenase reductase Sdr
CK207_RS05580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CK207_RS05590	COG4771	TonB-dependent receptor
CK207_RS05595	COG0657	acetylesterase activity
CK207_RS05605	COG0583	DNA-binding transcription factor activity
CK207_RS05615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK207_RS05620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK207_RS05625	COG1902	pentaerythritol trinitrate reductase activity
CK207_RS05635	COG2814	Major facilitator Superfamily
CK207_RS05640	COG1028	Short-chain dehydrogenase reductase Sdr
CK207_RS05655	COG0556	nucleotide-excision repair
CK207_RS05660	COG2204	response regulator
CK207_RS05665	COG2198	Histidine kinase
CK207_RS05670	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CK207_RS05675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CK207_RS05680	COG0521	Mo-molybdopterin cofactor biosynthetic process
CK207_RS05690	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CK207_RS05695	COG0314	molybdopterin synthase activity
CK207_RS05700	COG2199	diguanylate cyclase activity
CK207_RS05705	COG0517	IMP dehydrogenase activity
CK207_RS05705	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CK207_RS05705	COG0617	tRNA 3'-terminal CCA addition
CK207_RS05710	COG3335	DDE superfamily endonuclease
CK207_RS05720	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CK207_RS05730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK207_RS05730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK207_RS05735	COG0489	protein tyrosine kinase activity
CK207_RS05740	COG0572	uridine kinase
CK207_RS05745	COG2982	Protein involved in outer membrane biogenesis
CK207_RS05750	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CK207_RS05755	COG2067	long-chain fatty acid transport protein
CK207_RS05760	COG2067	long-chain fatty acid transport protein
CK207_RS05770	COG1595	DNA-templated transcription, initiation
CK207_RS05780	COG0183	Belongs to the thiolase family
CK207_RS05785	COG1250	3-hydroxyacyl-CoA dehydrogenase
CK207_RS05785	COG1024	Enoyl-CoA hydratase
CK207_RS05790	COG0778	Nitroreductase
CK207_RS05795	COG0583	DNA-binding transcription factor activity
CK207_RS05800	COG0745	RESPONSE REGULATOR receiver
CK207_RS05810	COG2832	Protein of unknown function (DUF454)
CK207_RS05815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CK207_RS05830	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CK207_RS05890	COG2433	Pfam Transposase IS66
CK207_RS05925	COG2226	methyltransferase
CK207_RS05940	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CK207_RS05950	COG3139	Protein of unknown function (DUF1315)
CK207_RS05955	COG0252	asparaginase activity
CK207_RS05960	COG0616	signal peptide processing
CK207_RS05965	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK207_RS05965	COG1902	pentaerythritol trinitrate reductase activity
CK207_RS05970	COG0788	formyltetrahydrofolate deformylase activity
CK207_RS05980	COG1199	ATP-dependent helicase activity
CK207_RS05985	COG1214	PFAM Peptidase M22, glycoprotease
CK207_RS06000	COG0596	Alpha beta hydrolase
CK207_RS06005	COG0318	PFAM AMP-dependent synthetase and ligase
CK207_RS06010	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CK207_RS06020	COG3385	transposase activity
CK207_RS06025	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CK207_RS06030	COG2894	cell division
CK207_RS06040	COG3100	YcgL domain-containing protein
CK207_RS06045	COG2951	lytic endotransglycosylase activity
CK207_RS06050	COG0583	DNA-binding transcription factor activity
CK207_RS06055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK207_RS06080	COG4628	conserved protein (DUF2132)
CK207_RS06095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK207_RS06105	COG0513	Belongs to the DEAD box helicase family
CK207_RS06115	COG1760	l-serine dehydratase
CK207_RS06120	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CK207_RS06130	COG2205	protein histidine kinase activity
CK207_RS06135	COG1653	transport
CK207_RS06145	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CK207_RS06150	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CK207_RS06155	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CK207_RS06175	COG0544	peptidyl-prolyl cis-trans isomerase activity
CK207_RS06185	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CK207_RS06190	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CK207_RS06195	COG0776	regulation of translation
CK207_RS06200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK207_RS06205	COG1555	photosystem II stabilization
CK207_RS06210	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CK207_RS06215	COG0539	negative regulation of cytoplasmic translation
CK207_RS06220	COG0776	regulation of translation
CK207_RS06225	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CK207_RS06230	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CK207_RS06245	COG0583	DNA-binding transcription factor activity
CK207_RS06255	COG0686	Belongs to the AlaDH PNT family
CK207_RS06260	COG1522	sequence-specific DNA binding
CK207_RS06265	COG1674	ftsk spoiiie
CK207_RS06275	COG0501	Belongs to the peptidase M48B family
CK207_RS06285	COG0300	oxidoreductase activity
CK207_RS06300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CK207_RS06310	COG2268	Band 7 protein
CK207_RS06320	COG1032	radical SAM domain protein
CK207_RS06345	COG0583	DNA-binding transcription factor activity
CK207_RS06350	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CK207_RS06360	COG2350	Protein conserved in bacteria
CK207_RS06390	COG0159	tryptophan synthase activity
CK207_RS06395	COG0133	tryptophan synthase activity
CK207_RS06400	COG0134	indole-3-glycerol-phosphate synthase activity
CK207_RS06400	COG0135	phosphoribosylanthranilate isomerase activity
CK207_RS06405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CK207_RS06410	COG0512	Glutamine amidotransferase of anthranilate synthase
CK207_RS06415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CK207_RS06425	COG0613	PHP domain protein
CK207_RS06430	COG0009	L-threonylcarbamoyladenylate synthase
CK207_RS06435	COG1187	pseudouridine synthase activity
CK207_RS06440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CK207_RS06445	COG4988	ABC transporter
CK207_RS06450	COG0492	ferredoxin-NADP+ reductase activity
CK207_RS06470	COG2949	membrane
CK207_RS06480	COG0281	malic enzyme
CK207_RS06490	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CK207_RS06495	COG2985	domain, Protein
CK207_RS06495	COG3273	potassium ion transport
CK207_RS06500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CK207_RS06510	COG1737	Transcriptional regulator
CK207_RS06515	COG0076	glutamate decarboxylase activity
CK207_RS06525	COG2431	L-lysine efflux transmembrane transporter activity
CK207_RS06535	COG3070	regulator of competence-specific genes
CK207_RS06550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK207_RS06550	COG4191	Histidine kinase
CK207_RS06560	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CK207_RS06565	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CK207_RS06570	COG2915	High frequency lysogenization protein hflD homolog
CK207_RS06575	COG0482	sulfurtransferase activity
CK207_RS06585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK207_RS06590	COG2916	Histone family protein nucleoid-structuring protein H-NS
CK207_RS06595	COG1757	Na H antiporter
CK207_RS06600	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CK207_RS06605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CK207_RS06610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CK207_RS06615	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CK207_RS06615	COG0131	Imidazoleglycerol-phosphate dehydratase
CK207_RS06620	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CK207_RS06625	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CK207_RS06630	COG0107	imidazoleglycerol-phosphate synthase activity
CK207_RS06635	COG0140	phosphoribosyl-ATP diphosphatase activity
CK207_RS06635	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CK207_RS06640	COG1187	pseudouridine synthase activity
CK207_RS06650	COG1278	Cold shock
CK207_RS06655	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CK207_RS06660	COG0542	response to heat
CK207_RS06665	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CK207_RS06670	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CK207_RS06675	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CK207_RS06690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CK207_RS06700	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CK207_RS06705	COG0297	glycogen (starch) synthase activity
CK207_RS06725	COG3070	regulator of competence-specific genes
CK207_RS06730	COG1609	Transcriptional regulator
CK207_RS06740	COG0745	RESPONSE REGULATOR receiver
CK207_RS06745	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CK207_RS06750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CK207_RS06760	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CK207_RS06765	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CK207_RS06780	COG0189	ligase activity
CK207_RS06780	COG4067	protein conserved in archaea
CK207_RS06785	COG0500	methyltransferase
CK207_RS06795	COG1801	Protein of unknown function DUF72
CK207_RS06800	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CK207_RS06805	COG1435	thymidine kinase activity
CK207_RS06815	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CK207_RS06840	COG2116	formate transmembrane transporter activity
CK207_RS06845	COG4459	periplasmic nitrate reductase
CK207_RS06850	COG3005	denitrification pathway
CK207_RS06855	COG0243	molybdopterin cofactor binding
CK207_RS06865	COG1227	inorganic diphosphatase activity
CK207_RS06910	COG2433	Pfam Transposase IS66
CK207_RS06915	COG4974	Belongs to the 'phage' integrase family
CK207_RS06940	COG3344	reverse transcriptase
CK207_RS06950	COG2433	Pfam Transposase IS66
CK207_RS06970	COG4172	Belongs to the ABC transporter superfamily
CK207_RS06980	COG4171	peptide transport system, permease
CK207_RS06995	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CK207_RS07000	COG1842	Phage shock protein A
CK207_RS07015	COG0519	Catalyzes the synthesis of GMP from XMP
CK207_RS07020	COG0626	cystathionine gamma-synthase activity
CK207_RS07030	COG0733	neurotransmitter:sodium symporter activity
CK207_RS07035	COG0564	pseudouridine synthase activity
CK207_RS07050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CK207_RS07055	COG4136	ATPase activity
CK207_RS07060	COG4135	transport system, permease component
CK207_RS07065	COG4134	Bacterial extracellular solute-binding protein
CK207_RS07075	COG3313	Fe-S protein
CK207_RS07085	COG0737	Belongs to the 5'-nucleotidase family
CK207_RS07095	COG0513	Belongs to the DEAD box helicase family
CK207_RS07110	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CK207_RS07115	COG2205	protein histidine kinase activity
CK207_RS07130	COG1061	Type III restriction enzyme res subunit
CK207_RS07135	COG1187	pseudouridine synthase activity
CK207_RS07140	COG2814	Major facilitator Superfamily
CK207_RS07150	COG0702	epimerase
CK207_RS07155	COG0534	Mate efflux family protein
CK207_RS07160	COG4181	ATPase activity
CK207_RS07175	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CK207_RS07200	COG0840	transmembrane signaling receptor activity
CK207_RS07230	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CK207_RS07235	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CK207_RS07240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CK207_RS07250	COG0840	transmembrane signaling receptor activity
CK207_RS07265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_RS07265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK207_RS07265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK207_RS07270	COG2207	Transcriptional regulator
CK207_RS07280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK207_RS07290	COG1342	Belongs to the UPF0251 family
CK207_RS07310	COG1129	ABC transporter
CK207_RS07320	COG0583	DNA-binding transcription factor activity
CK207_RS07325	COG3335	DDE superfamily endonuclease
CK207_RS07330	COG1902	pentaerythritol trinitrate reductase activity
CK207_RS07335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CK207_RS07340	COG5002	protein histidine kinase activity
CK207_RS07345	COG0745	RESPONSE REGULATOR receiver
CK207_RS07375	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CK207_RS07380	COG0372	Belongs to the citrate synthase family
CK207_RS07385	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CK207_RS07390	COG2828	Protein conserved in bacteria
CK207_RS07410	COG0561	phosphatase activity
CK207_RS07415	COG0602	queuosine metabolic process
CK207_RS07445	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CK207_RS07450	COG1254	Belongs to the acylphosphatase family
CK207_RS07455	COG3328	transposase activity
CK207_RS07460	COG2920	part of a sulfur-relay system
CK207_RS07465	COG0670	Belongs to the BI1 family
CK207_RS07470	COG1126	abc transporter atp-binding protein
CK207_RS07475	COG0765	amino acid transport
CK207_RS07480	COG4597	amino acid ABC transporter
CK207_RS07485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK207_RS07490	COG1648	precorrin-2 dehydrogenase activity
CK207_RS07490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CK207_RS07495	COG1666	GTP binding
CK207_RS07500	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CK207_RS07505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CK207_RS07505	COG0574	Belongs to the PEP-utilizing enzyme family
CK207_RS07520	COG2996	Protein conserved in bacteria
CK207_RS07530	COG3008	intermembrane lipid transfer
CK207_RS07535	COG2995	paraquat-inducible protein a
CK207_RS07540	COG1132	(ABC) transporter
CK207_RS07545	COG1956	GAF domain-containing protein
CK207_RS07550	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CK207_RS07565	COG0308	aminopeptidase N
CK207_RS07575	COG2902	Dehydrogenase
CK207_RS07580	COG0167	dihydroorotate dehydrogenase activity
CK207_RS07590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CK207_RS07590	COG0116	Belongs to the methyltransferase superfamily
CK207_RS07600	COG0488	(ABC) transporter
CK207_RS07615	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CK207_RS07620	COG1067	ATP-dependent peptidase activity
CK207_RS07625	COG3120	sequence-specific DNA binding
CK207_RS07655	COG2433	Pfam Transposase IS66
CK207_RS07725	COG0270	DNA (cytosine-5-)-methyltransferase activity
CK207_RS07780	COG3278	Belongs to the heme-copper respiratory oxidase family
CK207_RS07795	COG2010	Cytochrome c
CK207_RS07805	COG2217	Heavy metal translocating P-type atpase
CK207_RS07820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK207_RS07825	COG0589	response to stress
CK207_RS07830	COG2433	Pfam Transposase IS66
CK207_RS07865	COG3842	ATPase activity
CK207_RS07870	COG1176	ABC-type spermidine putrescine transport system, permease component I
CK207_RS07875	COG1177	transmembrane transport
CK207_RS07880	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CK207_RS07890	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CK207_RS07895	COG0004	ammonium transporteR
CK207_RS07900	COG0488	(ABC) transporter
CK207_RS07915	COG2271	Major facilitator Superfamily
CK207_RS07920	COG1840	ABC-type Fe3 transport system, periplasmic component
CK207_RS07930	COG3842	ATPase activity
CK207_RS07935	COG0746	molybdenum cofactor guanylyltransferase activity
CK207_RS07940	COG1763	Mo-molybdopterin cofactor biosynthetic process
CK207_RS07950	COG1940	carbohydrate kinase activity
CK207_RS07955	COG3148	PFAM DTW domain containing protein
CK207_RS07965	COG0840	transmembrane signaling receptor activity
CK207_RS07970	COG0791	NLP P60 protein
CK207_RS07980	COG3001	Fructosamine kinase
CK207_RS07995	COG1793	dna ligase
CK207_RS08000	COG4667	esterase of the alpha-beta hydrolase superfamily
CK207_RS08015	COG0848	biopolymer transport protein
CK207_RS08020	COG0811	peptide transport
CK207_RS08025	COG0811	peptide transport
CK207_RS08055	COG0625	glutathione transferase activity
CK207_RS08065	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CK207_RS08085	COG1115	amino acid carrier protein
CK207_RS08090	COG1280	lysine exporter protein (LysE YggA)
CK207_RS08095	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CK207_RS08100	COG0477	Major facilitator Superfamily
CK207_RS08115	COG1643	Atp-dependent helicase
CK207_RS08155	COG0443	Heat shock 70 kDa protein
CK207_RS08185	COG1609	Transcriptional regulator
CK207_RS08190	COG2723	6-phospho-beta-galactosidase activity
CK207_RS08195	COG0513	Belongs to the DEAD box helicase family
CK207_RS08200	COG0243	molybdopterin cofactor binding
CK207_RS08205	COG3005	denitrification pathway
CK207_RS08210	COG1278	Cold shock
CK207_RS08225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK207_RS08225	COG4191	Histidine kinase
CK207_RS08240	COG0471	metal ion transport
CK207_RS08250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CK207_RS08270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK207_RS08280	COG3768	UPF0283 membrane protein
CK207_RS08285	COG3106	COG3106 Predicted ATPase
CK207_RS08300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CK207_RS08305	COG0494	nUDIX hydrolase
CK207_RS08340	COG0814	amino acid
CK207_RS08345	COG1760	l-serine dehydratase
CK207_RS08355	COG2356	endonuclease I
CK207_RS08360	COG0720	synthase
CK207_RS08365	COG0840	transmembrane signaling receptor activity
CK207_RS08370	COG0017	Asparaginyl-tRNA synthetase
CK207_RS08380	COG2201	protein-glutamate methylesterase activity
CK207_RS08385	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CK207_RS08390	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CK207_RS08395	COG0835	chemotaxis
CK207_RS08405	COG0643	Histidine kinase
CK207_RS08405	COG2198	Histidine kinase
CK207_RS08415	COG0745	RESPONSE REGULATOR receiver
CK207_RS08420	COG0840	transmembrane signaling receptor activity
CK207_RS08425	COG3437	response regulator, receiver
CK207_RS08425	COG2770	Histidine kinase
CK207_RS08430	COG1448	Aminotransferase
CK207_RS08435	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CK207_RS08450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK207_RS08455	COG1846	Transcriptional regulator
CK207_RS08470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK207_RS08475	COG3108	Peptidase M15
CK207_RS08480	COG2989	Protein conserved in bacteria
CK207_RS08510	COG1940	carbohydrate kinase activity
CK207_RS08520	COG0748	coenzyme F420 binding
CK207_RS08525	COG3721	Heme iron utilization protein
CK207_RS08530	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CK207_RS08535	COG0811	peptide transport
CK207_RS08540	COG0848	biopolymer transport protein
CK207_RS08550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK207_RS08555	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CK207_RS08560	COG1054	Belongs to the UPF0176 family
CK207_RS08570	COG0840	transmembrane signaling receptor activity
CK207_RS08575	COG1621	beta-fructofuranosidase activity
CK207_RS08585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK207_RS08585	COG1263	PTS System
CK207_RS08590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK207_RS08595	COG2200	EAL domain
CK207_RS08600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CK207_RS08605	COG3335	DDE superfamily endonuclease
CK207_RS08675	COG3064	Membrane
CK207_RS08675	COG4991	sh3 domain protein
CK207_RS08675	COG0515	serine threonine protein kinase
CK207_RS08700	COG1716	ATPase activity
CK207_RS08720	COG1181	Belongs to the D-alanine--D-alanine ligase family
CK207_RS08795	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CK207_RS08840	COG0784	Response regulator, receiver
CK207_RS08840	COG0835	chemotaxis
CK207_RS08850	COG4565	transcriptional regulatory protein
CK207_RS08855	COG3290	protein histidine kinase activity
CK207_RS08870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK207_RS08895	COG3063	Type IV pilus biogenesis stability protein PilW
CK207_RS08910	COG1451	nucleotide metabolic process
CK207_RS08920	COG0583	DNA-binding transcription factor activity
CK207_RS08940	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CK207_RS08945	COG4139	cobalamin transport
CK207_RS08950	COG2988	succinylglutamate desuccinylase activity
CK207_RS08965	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CK207_RS08970	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CK207_RS08975	COG1073	alpha beta
CK207_RS08975	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CK207_RS08975	COG3064	Membrane
CK207_RS08980	COG2994	toxin metabolic process
CK207_RS09010	COG0702	epimerase
CK207_RS09015	COG1823	symporter activity
CK207_RS09020	COG2925	Exonuclease
CK207_RS09025	COG1380	Effector of murein hydrolase LrgA
CK207_RS09030	COG1346	cytolysis
CK207_RS09040	COG5001	Diguanylate cyclase
CK207_RS09065	COG0776	regulation of translation
CK207_RS09070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK207_RS09070	COG0072	phenylalanine-tRNA ligase activity
CK207_RS09075	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CK207_RS09115	COG0322	excinuclease ABC activity
CK207_RS09120	COG2197	response regulator
CK207_RS09125	COG0417	DNA replication proofreading
CK207_RS09135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CK207_RS09140	COG3099	Belongs to the UPF0263 family
CK207_RS09145	COG3097	Belongs to the UPF0267 family
CK207_RS09150	COG2188	Transcriptional regulator
CK207_RS09155	COG1228	amidohydrolase
CK207_RS09160	COG0010	Belongs to the arginase family
CK207_RS09170	COG2986	histidine ammonia-lyase
CK207_RS09185	COG0277	FAD linked oxidase domain protein
CK207_RS09185	COG0247	lactate metabolic process
CK207_RS09215	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CK207_RS09220	COG1960	acyl-CoA dehydrogenase activity
CK207_RS09265	COG0784	Response regulator, receiver
CK207_RS09265	COG5002	protein histidine kinase activity
CK207_RS09275	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CK207_RS09280	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CK207_RS09285	COG2885	chlorophyll binding
CK207_RS09290	COG0823	Involved in the tonB-independent uptake of proteins
CK207_RS09305	COG0811	peptide transport
CK207_RS09310	COG0824	Thioesterase
CK207_RS09315	COG3790	cyd operon protein YbgE
CK207_RS09320	COG4890	Cyd operon protein YbgT
CK207_RS09325	COG1294	oxidase, subunit
CK207_RS09330	COG1271	oxidase subunit
CK207_RS09335	COG2255	four-way junction helicase activity
CK207_RS09340	COG0632	four-way junction helicase activity
CK207_RS09345	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CK207_RS09350	COG0215	cysteine-tRNA ligase activity
CK207_RS09355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CK207_RS09360	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK207_RS09365	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CK207_RS09370	COG3012	SEC-C Motif Domain Protein
CK207_RS09385	COG1199	ATP-dependent helicase activity
CK207_RS09395	COG3923	Primosomal replication protein n
CK207_RS09405	COG0840	transmembrane signaling receptor activity
CK207_RS09435	COG2433	Pfam Transposase IS66
CK207_RS09455	COG0708	Exodeoxyribonuclease III
CK207_RS09460	COG4160	amino acid transport
CK207_RS09490	COG1882	Formate acetyltransferase
CK207_RS09505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CK207_RS09515	COG3013	Belongs to the UPF0304 family
CK207_RS09520	COG2766	serine protein kinase
CK207_RS09525	COG2718	Belongs to the UPF0229 family
CK207_RS09530	COG2719	SpoVR family
CK207_RS09535	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CK207_RS09550	COG1132	(ABC) transporter
CK207_RS09555	COG2333	competence protein COMEC
CK207_RS09555	COG0658	competence protein
CK207_RS09565	COG4591	ABC-type transport system involved in lipoprotein release permease component
CK207_RS09570	COG1136	(ABC) transporter
CK207_RS09575	COG4591	ABC-type transport system involved in lipoprotein release permease component
CK207_RS09585	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CK207_RS09600	COG1252	NADH dehydrogenase
CK207_RS09605	COG3150	esterase
CK207_RS09630	COG0537	adenosine 5'-monophosphoramidase activity
CK207_RS09645	COG2186	Transcriptional regulator
CK207_RS09650	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CK207_RS09660	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CK207_RS09665	COG2226	methyltransferase
CK207_RS09675	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CK207_RS09680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CK207_RS09690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CK207_RS09695	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CK207_RS09705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK207_RS09715	COG4120	Belongs to the binding-protein-dependent transport system permease family
CK207_RS09725	COG3092	negative regulation of chromosome organization
CK207_RS09730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CK207_RS09735	COG0857	belongs to the CobB CobQ family
CK207_RS09735	COG0280	phosphate acetyltransferase
CK207_RS09740	COG0435	Glutathione S-transferase
CK207_RS09750	COG0444	Belongs to the ABC transporter superfamily
CK207_RS09755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK207_RS09760	COG0601	transmembrane transport
CK207_RS09775	COG5002	protein histidine kinase activity
CK207_RS09775	COG0784	Response regulator, receiver
CK207_RS09800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK207_RS09805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK207_RS09825	COG1216	Glycosyl transferase, family 2
CK207_RS09855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CK207_RS09865	COG1028	Short-chain dehydrogenase reductase Sdr
CK207_RS09905	COG2433	Pfam Transposase IS66
CK207_RS09920	COG0800	Aldolase
CK207_RS09925	COG2610	gluconate transmembrane transporter activity
CK207_RS09930	COG3265	gluconokinase activity
CK207_RS09935	COG0129	dihydroxy-acid dehydratase activity
CK207_RS09940	COG1609	Transcriptional regulator
CK207_RS09955	COG5002	protein histidine kinase activity
CK207_RS09955	COG3850	Histidine kinase
CK207_RS09965	COG2985	domain, Protein
CK207_RS09980	COG2194	sulfuric ester hydrolase activity
CK207_RS09995	COG2433	Pfam Transposase IS66
CK207_RS10005	COG0642	Histidine kinase
CK207_RS10010	COG0745	RESPONSE REGULATOR receiver
CK207_RS10020	COG0300	oxidoreductase activity
CK207_RS10030	COG1022	Amp-dependent synthetase and ligase
CK207_RS10040	COG3335	DDE superfamily endonuclease
CK207_RS10060	COG1061	Type III restriction enzyme res subunit
CK207_RS10080	COG3335	DDE superfamily endonuclease
CK207_RS10105	COG3706	GGDEF domain
CK207_RS10120	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CK207_RS10125	COG1946	Acyl-CoA thioesterase
CK207_RS10130	COG1522	sequence-specific DNA binding
CK207_RS10165	COG0318	PFAM AMP-dependent synthetase and ligase
CK207_RS10175	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CK207_RS10185	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CK207_RS10190	COG1169	isochorismate synthase
CK207_RS10200	COG0436	Aminotransferase
CK207_RS10205	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CK207_RS10210	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CK207_RS10225	COG0616	signal peptide processing
CK207_RS10230	COG1028	Short-chain dehydrogenase reductase Sdr
CK207_RS10235	COG0835	chemotaxis
CK207_RS10235	COG0784	Response regulator, receiver
CK207_RS10240	COG1940	carbohydrate kinase activity
CK207_RS10250	COG4667	esterase of the alpha-beta hydrolase superfamily
CK207_RS10265	COG0733	neurotransmitter:sodium symporter activity
CK207_RS10275	COG1263	PTS System
CK207_RS10275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK207_RS10280	COG0084	hydrolase, TatD family'
CK207_RS10285	COG0470	DNA polymerase III
CK207_RS10290	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CK207_RS10295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CK207_RS10300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK207_RS10325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CK207_RS10340	COG1399	metal-binding, possibly nucleic acid-binding protein
CK207_RS10345	COG0424	maF-like protein
CK207_RS10350	COG0564	pseudouridine synthase activity
CK207_RS10355	COG1530	ribonuclease E activity
CK207_RS10365	COG1454	alcohol dehydrogenase
CK207_RS10365	COG1012	belongs to the aldehyde dehydrogenase family
CK207_RS10370	COG2095	MarC family integral membrane protein
CK207_RS10375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CK207_RS10380	COG1757	Na H antiporter
CK207_RS10385	COG3385	transposase activity
CK207_RS10400	COG3082	Protein of unknown function (DUF1414)
CK207_RS10415	COG0243	molybdopterin cofactor binding
CK207_RS10420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CK207_RS10435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CK207_RS10475	COG3501	Rhs element vgr protein
CK207_RS10505	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CK207_RS10515	COG1196	nuclear chromosome segregation
CK207_RS10520	COG0732	type I restriction modification DNA specificity domain
CK207_RS10570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CK207_RS10575	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CK207_RS10595	COG2853	Lipoprotein
CK207_RS10610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CK207_RS10615	COG1138	Cytochrome C-type biogenesis protein
CK207_RS10620	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CK207_RS10630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CK207_RS10635	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CK207_RS10640	COG4133	protoheme IX ABC transporter activity
CK207_RS10650	COG0835	chemotaxis
CK207_RS10660	COG1192	Involved in chromosome partitioning
CK207_RS10665	COG2201	protein-glutamate methylesterase activity
CK207_RS10670	COG0643	Histidine kinase
CK207_RS10670	COG0784	Response regulator, receiver
CK207_RS10670	COG2198	Histidine kinase
CK207_RS10675	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CK207_RS10700	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CK207_RS10705	COG2062	phosphohistidine phosphatase, SixA
CK207_RS10710	COG1025	Belongs to the peptidase M16 family
CK207_RS10715	COG3102	Protein conserved in bacteria
CK207_RS10740	COG1918	ferrous iron import across plasma membrane
CK207_RS10745	COG4977	sequence-specific DNA binding
CK207_RS10750	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CK207_RS10755	COG1121	(ABC) transporter
CK207_RS10760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CK207_RS10775	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK207_RS10780	COG0567	Dehydrogenase, E1 component
CK207_RS10795	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CK207_RS10810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CK207_RS10820	COG0033	Phosphoglucomutase
CK207_RS10825	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CK207_RS10830	COG0596	Alpha beta hydrolase
CK207_RS10845	COG1346	cytolysis
CK207_RS10855	COG0583	DNA-binding transcription factor activity
CK207_RS10865	COG0735	belongs to the Fur family
CK207_RS10870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CK207_RS10875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CK207_RS10880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CK207_RS10885	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CK207_RS10885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK207_RS10890	COG0431	NADPH-dependent FMN reductase
CK207_RS10900	COG3101	peptidyl-lysine hydroxylation
CK207_RS10905	COG2860	membrane
CK207_RS10910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CK207_RS10915	COG2890	protein-(glutamine-N5) methyltransferase activity
CK207_RS10920	COG2840	Smr protein MutS2
CK207_RS10930	COG1684	flagellar biosynthetic protein fliR
CK207_RS10935	COG1987	bacterial-type flagellum assembly
CK207_RS10985	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CK207_RS10995	COG1677	Flagellar hook-basal body complex protein FliE
CK207_RS11015	COG1516	flagellar protein fliS
CK207_RS11025	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CK207_RS11050	COG2837	iron assimilation
CK207_RS11075	COG1393	Belongs to the ArsC family
CK207_RS11095	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CK207_RS11110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CK207_RS11120	COG2433	Pfam Transposase IS66
CK207_RS11155	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CK207_RS11180	COG2433	Pfam Transposase IS66
CK207_RS11215	COG2433	Pfam Transposase IS66
CK207_RS11220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK207_RS11220	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CK207_RS11225	COG3550	peptidyl-serine autophosphorylation
CK207_RS11260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CK207_RS11280	COG4783	chaperone-mediated protein folding
CK207_RS11285	COG1393	Belongs to the ArsC family
CK207_RS11305	COG2233	PERMEase
CK207_RS11310	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CK207_RS11320	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CK207_RS11325	COG2912	Transglutaminase-like superfamily
CK207_RS11335	COG2890	protein-(glutamine-N5) methyltransferase activity
CK207_RS11340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CK207_RS11345	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CK207_RS11350	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CK207_RS11360	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CK207_RS11365	COG0193	aminoacyl-tRNA hydrolase activity
CK207_RS11470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CK207_RS11480	COG3951	Flagellar rod assembly protein muramidase FlgJ
CK207_RS11480	COG1705	Flagellar rod assembly protein muramidase FlgJ
CK207_RS11485	COG1706	bacterial-type flagellum-dependent cell motility
CK207_RS11490	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CK207_RS11500	COG4787	bacterial-type flagellum-dependent cell motility
CK207_RS11505	COG1749	Flagellar hook protein flgE
CK207_RS11520	COG1815	bacterial-type flagellum-dependent cell motility
CK207_RS11530	COG0784	Response regulator, receiver
CK207_RS11530	COG0835	chemotaxis
CK207_RS11540	COG2747	anti-sigma28 factor FlgM
CK207_RS11585	COG2217	Heavy metal translocating P-type atpase
CK207_RS11585	COG2608	mercury ion transmembrane transporter activity
CK207_RS11610	COG3385	transposase activity
CK207_RS11615	COG1187	pseudouridine synthase activity
CK207_RS11620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CK207_RS11625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CK207_RS11630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CK207_RS11635	COG0121	glutamine amidotransferase
CK207_RS11640	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CK207_RS11660	COG0328	RNA-DNA hybrid ribonuclease activity
CK207_RS11665	COG2226	methyltransferase
CK207_RS11670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK207_RS11675	COG0741	lytic transglycosylase activity
CK207_RS11675	COG1388	LysM domain
CK207_RS11685	COG3021	interspecies interaction between organisms
CK207_RS11690	COG0347	Belongs to the P(II) protein family
CK207_RS11700	COG0037	tRNA processing
CK207_RS11705	COG0825	malonyl-CoA metabolic process
CK207_RS11710	COG0587	DNA-directed DNA polymerase activity
CK207_RS11720	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK207_RS11730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CK207_RS11735	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK207_RS11740	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CK207_RS11750	COG0750	zinc metalloprotease
CK207_RS11755	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CK207_RS11760	COG0575	Belongs to the CDS family
CK207_RS11765	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CK207_RS11770	COG0233	cytoplasmic translational termination
CK207_RS11780	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CK207_RS11785	COG0052	Belongs to the universal ribosomal protein uS2 family
CK207_RS11790	COG0024	Methionine aminopeptidase
CK207_RS11795	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CK207_RS11805	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CK207_RS11810	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CK207_RS11815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CK207_RS11835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CK207_RS11835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CK207_RS11840	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CK207_RS11845	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CK207_RS11850	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CK207_RS11860	COG1073	alpha beta
CK207_RS11865	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CK207_RS11870	COG2252	PERMEase
CK207_RS11875	COG2195	Cleaves the N-terminal amino acid of tripeptides
CK207_RS11880	COG4067	protein conserved in archaea
CK207_RS11880	COG0189	ligase activity
CK207_RS11885	COG0189	ligase activity
CK207_RS11895	COG0733	neurotransmitter:sodium symporter activity
CK207_RS11900	COG2203	Gaf domain
CK207_RS11900	COG3706	GGDEF domain
CK207_RS11900	COG4251	negative regulation of phosphorylation
CK207_RS11900	COG5001	Diguanylate cyclase
CK207_RS11910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CK207_RS11920	COG1477	protein flavinylation
CK207_RS11955	COG0271	Belongs to the BolA IbaG family
CK207_RS11975	COG2211	Major facilitator Superfamily
CK207_RS11985	COG1595	DNA-templated transcription, initiation
CK207_RS12000	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CK207_RS12010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CK207_RS12015	COG2166	iron-sulfur cluster assembly
CK207_RS12020	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CK207_RS12025	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CK207_RS12035	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CK207_RS12035	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CK207_RS12045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CK207_RS12050	COG1074	ATP-dependent DNA helicase activity
CK207_RS12055	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CK207_RS12070	COG3141	response to X-ray
CK207_RS12075	COG2171	N-acyltransferase activity
CK207_RS12105	COG1609	Transcriptional regulator
CK207_RS12115	COG1085	galactose-1-phosphate uridylyltransferase
CK207_RS12130	COG0784	Response regulator, receiver
CK207_RS12130	COG3437	response regulator, receiver
CK207_RS12135	COG1022	Amp-dependent synthetase and ligase
CK207_RS12140	COG4628	conserved protein (DUF2132)
CK207_RS12145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CK207_RS12150	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CK207_RS12160	COG0560	Phosphoserine phosphatase
CK207_RS12170	COG0813	purine-nucleoside phosphorylase activity
CK207_RS12175	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CK207_RS12180	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CK207_RS12185	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CK207_RS12190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK207_RS12195	COG0084	hydrolase, TatD family'
CK207_RS12200	COG3022	response to hydroperoxide
CK207_RS12205	COG1115	amino acid carrier protein
CK207_RS12220	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CK207_RS12225	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CK207_RS12230	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CK207_RS12235	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CK207_RS12240	COG0083	homoserine kinase activity
CK207_RS12255	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CK207_RS12260	COG3335	DDE superfamily endonuclease
CK207_RS12265	COG0745	RESPONSE REGULATOR receiver
CK207_RS12275	COG0784	Response regulator, receiver
CK207_RS12275	COG2198	Histidine kinase
CK207_RS12275	COG5002	protein histidine kinase activity
CK207_RS12280	COG1242	4 iron, 4 sulfur cluster binding
CK207_RS12285	COG0067	glutamate synthase
CK207_RS12285	COG0069	glutamate synthase activity
CK207_RS12285	COG0070	glutamate synthase
CK207_RS12295	COG0069	glutamate synthase activity
CK207_RS12295	COG0070	glutamate synthase
CK207_RS12295	COG0067	glutamate synthase
CK207_RS12300	COG0493	'glutamate synthase
CK207_RS12310	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CK207_RS12320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CK207_RS12325	COG2860	membrane
CK207_RS12330	COG0583	DNA-binding transcription factor activity
CK207_RS12335	COG0730	response to heat
CK207_RS12340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CK207_RS12345	COG0505	Belongs to the CarA family
CK207_RS12350	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CK207_RS12355	COG0494	nUDIX hydrolase
CK207_RS12360	COG0653	protein targeting
CK207_RS12370	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CK207_RS12375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CK207_RS12380	COG0849	cell division
CK207_RS12385	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CK207_RS12390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CK207_RS12395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CK207_RS12400	COG0772	Belongs to the SEDS family
CK207_RS12405	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CK207_RS12415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CK207_RS12420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CK207_RS12425	COG0768	penicillin binding
CK207_RS12430	COG3116	cell division
CK207_RS12435	COG0275	rRNA processing
CK207_RS12445	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CK207_RS12450	COG3107	peptidoglycan biosynthetic process
CK207_RS12455	COG0792	nuclease activity
CK207_RS12460	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CK207_RS12470	COG2969	positive regulation of protein catabolic process
CK207_RS12475	COG0625	glutathione transferase activity
CK207_RS12480	COG2857	Cytochrome c1
CK207_RS12485	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CK207_RS12490	COG0723	plastoquinol--plastocyanin reductase activity
CK207_RS12500	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CK207_RS12510	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CK207_RS12515	COG3105	Protein conserved in bacteria
CK207_RS12520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK207_RS12525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK207_RS12530	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CK207_RS12535	COG0187	DNA topoisomerase II activity
CK207_RS12540	COG3150	esterase
CK207_RS12550	COG3151	Protein conserved in bacteria
CK207_RS12555	COG0494	nUDIX hydrolase
CK207_RS12560	COG1538	Outer membrane efflux protein
CK207_RS12570	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CK207_RS12585	COG3025	triphosphatase activity
CK207_RS12590	COG1392	Phosphate transport regulator
CK207_RS12595	COG0306	phosphate transporter
CK207_RS12600	COG4991	sh3 domain protein
CK207_RS12610	COG3267	Type II secretory pathway component ExeA
CK207_RS12610	COG3409	Peptidoglycan-binding domain 1 protein
CK207_RS12615	COG0617	tRNA 3'-terminal CCA addition
CK207_RS12625	COG0504	CTP synthase activity
CK207_RS12630	COG3956	TIGRFAM MazG family protein
CK207_RS12635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CK207_RS12640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CK207_RS12645	COG3437	response regulator, receiver
CK207_RS12645	COG4999	Histidine kinase
CK207_RS12645	COG3850	Histidine kinase
CK207_RS12645	COG2205	protein histidine kinase activity
CK207_RS12650	COG0736	holo-[acyl-carrier-protein] synthase activity
CK207_RS12655	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CK207_RS12660	COG1381	Involved in DNA repair and RecF pathway recombination
CK207_RS12665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CK207_RS12670	COG0571	ribonuclease III activity
CK207_RS12680	COG0481	GTPase activity
CK207_RS12685	COG3086	response to oxidative stress
CK207_RS12700	COG1595	DNA-templated transcription, initiation
CK207_RS12705	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CK207_RS12715	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CK207_RS12735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK207_RS12740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK207_RS12745	COG3079	Belongs to the UPF0149 family
CK207_RS12750	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CK207_RS12760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CK207_RS12770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CK207_RS12780	COG0028	Belongs to the TPP enzyme family
CK207_RS12785	COG1022	Amp-dependent synthetase and ligase
CK207_RS12790	COG0583	DNA-binding transcription factor activity
CK207_RS12795	COG3335	DDE superfamily endonuclease
CK207_RS12815	COG0473	3-isopropylmalate dehydrogenase activity
CK207_RS12825	COG0066	3-isopropylmalate dehydratase activity
CK207_RS12875	COG3328	transposase activity
CK207_RS12895	COG0795	lipopolysaccharide-transporting ATPase activity
CK207_RS12900	COG0795	lipopolysaccharide-transporting ATPase activity
CK207_RS12905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CK207_RS12910	COG2927	DNA polymerase III (CHI subunit)
CK207_RS12915	COG0525	valine-tRNA ligase activity
CK207_RS12920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CK207_RS12925	COG0564	pseudouridine synthase activity
CK207_RS12935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CK207_RS12945	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CK207_RS12960	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CK207_RS12965	COG0251	oxidation-reduction process
CK207_RS12980	COG0204	Acyl-transferase
CK207_RS12985	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CK207_RS12990	COG5007	Belongs to the BolA IbaG family
CK207_RS13000	COG2854	intermembrane phospholipid transfer
CK207_RS13005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CK207_RS13010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CK207_RS13015	COG1127	ABC transporter
CK207_RS13025	COG0517	IMP dehydrogenase activity
CK207_RS13025	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CK207_RS13040	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CK207_RS13045	COG1137	ATPase activity
CK207_RS13055	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CK207_RS13060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_RS13065	COG1660	Displays ATPase and GTPase activities
CK207_RS13070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_RS13075	COG2239	Acts as a magnesium transporter
CK207_RS13080	COG0312	modulator of DNA gyrase
CK207_RS13085	COG3028	Belongs to the UPF0307 family
CK207_RS13090	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CK207_RS13095	COG1178	ABC-type Fe3 transport system permease component
CK207_RS13105	COG0163	prenyltransferase activity
CK207_RS13110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CK207_RS13115	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CK207_RS13120	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CK207_RS13130	COG2105	PFAM AIG2 family protein
CK207_RS13135	COG2911	Protein conserved in bacteria
CK207_RS13140	COG0729	surface antigen
CK207_RS13145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CK207_RS13150	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CK207_RS13185	COG0529	Catalyzes the synthesis of activated sulfate
CK207_RS13190	COG2895	sulfate adenylyltransferase (ATP) activity
CK207_RS13195	COG0175	sulfate reduction
CK207_RS13200	COG1648	precorrin-2 dehydrogenase activity
CK207_RS13200	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CK207_RS13230	COG3335	DDE superfamily endonuclease
CK207_RS13255	COG0513	Belongs to the DEAD box helicase family
CK207_RS13260	COG2153	protein acetylation
CK207_RS13265	COG3061	Opacity-associated protein A
CK207_RS13265	COG3266	domain, Protein
CK207_RS13270	COG0545	Peptidyl-prolyl cis-trans isomerase
CK207_RS13275	COG0203	ribosomal protein L17
CK207_RS13280	COG0202	RNA polymerase activity
CK207_RS13285	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CK207_RS13290	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CK207_RS13295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CK207_RS13300	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CK207_RS13305	COG0201	protein transport
CK207_RS13310	COG0200	Binds to the 23S rRNA
CK207_RS13315	COG1841	ribosomal large subunit assembly
CK207_RS13320	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CK207_RS13330	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CK207_RS13335	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CK207_RS13340	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CK207_RS13345	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CK207_RS13350	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CK207_RS13360	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CK207_RS13370	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CK207_RS13385	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CK207_RS13390	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CK207_RS13400	COG0088	Forms part of the polypeptide exit tunnel
CK207_RS13405	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CK207_RS13410	COG0051	transcription antitermination factor activity, RNA binding
CK207_RS13415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CK207_RS13420	COG0557	exoribonuclease II activity
CK207_RS13425	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CK207_RS13435	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CK207_RS13445	COG1047	Peptidyl-prolyl cis-trans
CK207_RS13450	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CK207_RS13460	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK207_RS13465	COG0488	(ABC) transporter
CK207_RS13475	COG0429	hydrolase of the alpha beta-hydrolase fold
CK207_RS13485	COG3954	Phosphoribulokinase
CK207_RS13490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK207_RS13500	COG1012	belongs to the aldehyde dehydrogenase family
CK207_RS13510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CK207_RS13525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK207_RS13535	COG0583	DNA-binding transcription factor activity
CK207_RS13550	COG0180	Tryptophanyl-tRNA synthetase
CK207_RS13555	COG0546	phosphoglycolate phosphatase activity
CK207_RS13560	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CK207_RS13565	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CK207_RS13575	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CK207_RS13580	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CK207_RS13610	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CK207_RS13620	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CK207_RS13620	COG0678	peroxiredoxin activity
CK207_RS13625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK207_RS13635	COG0165	Argininosuccinate lyase
CK207_RS13635	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CK207_RS13640	COG0137	argininosuccinate synthase activity
CK207_RS13645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CK207_RS13650	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CK207_RS13655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CK207_RS13660	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CK207_RS13670	COG1045	serine acetyltransferase
CK207_RS13675	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CK207_RS13685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CK207_RS13690	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CK207_RS13695	COG1053	succinate dehydrogenase
CK207_RS13700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CK207_RS13705	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CK207_RS13715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CK207_RS13720	COG1509	lysine 2,3-aminomutase activity
CK207_RS13745	COG0459	protein refolding
CK207_RS13750	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CK207_RS13780	COG0534	Mate efflux family protein
CK207_RS13855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CK207_RS13860	COG1575	Belongs to the MenA family. Type 1 subfamily
CK207_RS13865	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CK207_RS13870	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CK207_RS13880	COG1609	Transcriptional regulator
CK207_RS13885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CK207_RS13895	COG0281	malic enzyme
CK207_RS13905	COG0626	cystathionine gamma-synthase activity
CK207_RS13910	COG0460	homoserine dehydrogenase
CK207_RS13910	COG0527	aspartate kinase activity
CK207_RS13915	COG3385	transposase activity
CK207_RS13920	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CK207_RS13925	COG3074	FtsZ-dependent cytokinesis
CK207_RS13930	COG1494	fructose-1,6-bisphosphatase
CK207_RS13935	COG0205	6-phosphofructokinase activity
CK207_RS13940	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CK207_RS13950	COG0745	RESPONSE REGULATOR receiver
CK207_RS13955	COG2205	protein histidine kinase activity
CK207_RS13960	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CK207_RS13965	COG1278	Cold shock
CK207_RS13970	COG3030	protein affecting phage T7 exclusion by the F plasmid
CK207_RS13975	COG1027	Aspartate ammonia-lyase
CK207_RS13980	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CK207_RS13985	COG1288	antiporter activity
CK207_RS13995	COG0549	Belongs to the carbamate kinase family
CK207_RS14000	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CK207_RS14010	COG0540	Belongs to the ATCase OTCase family
CK207_RS14015	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CK207_RS14020	COG1438	arginine binding
CK207_RS14025	COG4232	protein-disulfide reductase activity
CK207_RS14045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK207_RS14050	COG2198	Histidine kinase
CK207_RS14050	COG0784	Response regulator, receiver
CK207_RS14050	COG2205	protein histidine kinase activity
CK207_RS14055	COG2814	Major facilitator Superfamily
CK207_RS14070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK207_RS14075	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CK207_RS14080	COG0511	ligase activity, forming carbon-carbon bonds
CK207_RS14085	COG0439	Biotin carboxylase
CK207_RS14090	COG2264	protein methyltransferase activity
CK207_RS14095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK207_RS14100	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CK207_RS14105	COG0840	transmembrane signaling receptor activity
CK207_RS14110	COG0789	Transcriptional regulator
CK207_RS14115	COG0138	bifunctional purine biosynthesis protein purh
CK207_RS14120	COG0151	Belongs to the GarS family
CK207_RS14130	COG0776	regulation of translation
CK207_RS14135	COG1253	flavin adenine dinucleotide binding
CK207_RS14180	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CK207_RS14190	COG3068	Protein conserved in bacteria
CK207_RS14195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CK207_RS14200	COG0668	transmembrane transport
CK207_RS14215	COG4372	Transposase
CK207_RS14230	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CK207_RS14240	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CK207_RS14250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CK207_RS14315	COG3335	DDE superfamily endonuclease
CK207_RS14335	COG0367	asparagine synthase
CK207_RS14360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CK207_RS14370	COG5433	transposase activity
CK207_RS14395	COG3307	-O-antigen
CK207_RS14405	COG0859	PFAM glycosyl transferase family 9
CK207_RS14420	COG1519	Transferase
CK207_RS14450	COG2755	lipolytic protein G-D-S-L family
CK207_RS14450	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CK207_RS14455	COG3642	lipopolysaccharide core region biosynthetic process
CK207_RS14460	COG0859	PFAM glycosyl transferase family 9
CK207_RS14465	COG0463	Glycosyl transferase, family 2
CK207_RS14470	COG0859	PFAM glycosyl transferase family 9
CK207_RS14475	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CK207_RS14480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CK207_RS14490	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CK207_RS14495	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CK207_RS14500	COG2003	Belongs to the UPF0758 family
CK207_RS14505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CK207_RS14510	COG1309	transcriptional regulator
CK207_RS14515	COG1560	Kdo2-lipid A biosynthetic process
CK207_RS14520	COG1560	Kdo2-lipid A biosynthetic process
CK207_RS14525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CK207_RS14530	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CK207_RS14535	COG1561	YicC-like family, N-terminal region
CK207_RS14550	COG3385	transposase activity
CK207_RS14555	COG0612	Peptidase, M16
CK207_RS14560	COG2862	Uncharacterized protein family, UPF0114
CK207_RS14575	COG1120	ATPase activity
CK207_RS14580	COG4774	siderophore transport
CK207_RS14585	COG1132	(ABC) transporter
CK207_RS14590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CK207_RS14590	COG1263	PTS System
CK207_RS14595	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CK207_RS14615	COG0514	ATP-dependent DNA helicase (RecQ)
CK207_RS14620	COG2962	Rard protein
CK207_RS14630	COG1280	lysine exporter protein (LysE YggA)
CK207_RS14635	COG0210	DNA helicase
CK207_RS14640	COG0339	signal peptide processing
CK207_RS14645	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CK207_RS14650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK207_RS14685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK207_RS14690	COG0601	transmembrane transport
CK207_RS14740	COG1309	transcriptional regulator
CK207_RS14745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK207_RS14750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK207_RS14755	COG2960	long-chain fatty acid transporting porin activity
CK207_RS14760	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CK207_RS14780	COG3078	GTPase activator activity
CK207_RS14800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CK207_RS14800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CK207_RS14810	COG0084	hydrolase, TatD family'
CK207_RS14825	COG0805	protein transport
CK207_RS14830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CK207_RS14835	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CK207_RS14840	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CK207_RS14850	COG2226	methyltransferase
CK207_RS14855	COG1322	Protein conserved in bacteria
CK207_RS14860	COG0697	spore germination
CK207_RS14925	COG2433	Pfam Transposase IS66
CK207_RS14955	COG2433	Pfam Transposase IS66
CK207_RS14960	COG3335	DDE superfamily endonuclease
CK207_RS14980	COG2433	Pfam Transposase IS66
CK207_RS15010	COG0606	chelatase, subunit chli
CK207_RS15020	COG3978	acetolactate synthase activity
CK207_RS15025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK207_RS15040	COG0604	alcohol dehydrogenase
CK207_RS15055	COG0425	Belongs to the sulfur carrier protein TusA family
CK207_RS15065	COG2119	membrane
CK207_RS15070	COG0752	glycyl-tRNA synthetase alpha subunit
CK207_RS15080	COG3977	Valine--pyruvate aminotransferase
CK207_RS15085	COG0071	Belongs to the small heat shock protein (HSP20) family
CK207_RS15105	COG0187	DNA topoisomerase II activity
CK207_RS15110	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CK207_RS15115	COG0592	DNA-directed DNA polymerase activity
CK207_RS15135	COG1126	abc transporter atp-binding protein
CK207_RS15155	COG0706	membrane insertase activity
CK207_RS15165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CK207_RS15195	COG2084	Dehydrogenase
CK207_RS15200	COG0814	amino acid
CK207_RS15230	COG0583	DNA-binding transcription factor activity
CK207_RS15235	COG2910	NAD(P)H-binding
CK207_RS15245	COG3304	Inner membrane component domain
CK207_RS15265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CK207_RS15270	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CK207_RS15290	COG0363	glucosamine-6-phosphate deaminase activity
CK207_RS15300	COG0739	heme binding
CK207_RS15305	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_RS15305	COG2213	PTS system mannitol-specific
CK207_RS15310	COG0246	Mannitol dehydrogenase
CK207_RS15315	COG3722	fumarate hydratase activity
CK207_RS15325	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CK207_RS15330	COG1301	dicarboxylic acid transport
CK207_RS15335	COG2259	Doxx family
CK207_RS15355	COG1566	PFAM secretion protein HlyD family protein
CK207_RS15360	COG1846	Transcriptional regulator
CK207_RS15370	COG3046	protein related to deoxyribodipyrimidine photolyase
CK207_RS15375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CK207_RS15385	COG3335	DDE superfamily endonuclease
CK207_RS15390	COG0842	Transport permease protein
CK207_RS15395	COG1131	(ABC) transporter
CK207_RS15410	COG3842	ATPase activity
CK207_RS15420	COG1175	transmembrane transport
CK207_RS15440	COG0513	Belongs to the DEAD box helicase family
CK207_RS15445	COG0251	oxidation-reduction process
CK207_RS15450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CK207_RS15460	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CK207_RS15465	COG1328	CTP reductase activity
CK207_RS15475	COG2130	NADP-dependent
CK207_RS15480	COG1309	transcriptional regulator
CK207_RS15495	COG0745	RESPONSE REGULATOR receiver
CK207_RS15505	COG0564	pseudouridine synthase activity
CK207_RS15510	COG3335	DDE superfamily endonuclease
CK207_RS15520	COG3335	DDE superfamily endonuclease
CK207_RS15560	COG3335	DDE superfamily endonuclease
CK207_RS15585	COG3829	transcription factor binding
CK207_RS15610	COG3409	Peptidoglycan-binding domain 1 protein
CK207_RS15610	COG3501	Rhs element vgr protein
CK207_RS15655	COG2433	Pfam Transposase IS66
CK207_RS15680	COG0471	metal ion transport
CK207_RS15685	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CK207_RS15690	COG3335	DDE superfamily endonuclease
CK207_RS15700	COG2188	Transcriptional regulator
CK207_RS15705	COG1131	(ABC) transporter
CK207_RS15735	COG0671	phosphoesterase, PA-phosphatase related
CK207_RS15745	COG1132	(ABC) transporter
CK207_RS15765	COG3623	hexulose-6-phosphate isomerase
CK207_RS15770	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CK207_RS15775	COG0561	phosphatase activity
CK207_RS15825	COG3335	DDE superfamily endonuclease
CK207_RS15840	COG0366	Alpha amylase catalytic
CK207_RS15850	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CK207_RS15860	COG1999	signal sequence binding
CK207_RS15875	COG0786	glutamate:sodium symporter activity
CK207_RS15905	COG1566	PFAM secretion protein HlyD family protein
CK207_RS15930	COG0813	purine-nucleoside phosphorylase activity
CK207_RS15935	COG3272	Protein of unknown function (DUF1722)
CK207_RS15940	COG0789	Transcriptional regulator
CK207_RS15945	COG0415	Belongs to the DNA photolyase family
CK207_RS15950	COG1388	LysM domain
CK207_RS15950	COG1376	ErfK ybiS ycfS ynhG family protein
CK207_RS15960	COG0513	Belongs to the DEAD box helicase family
CK207_RS15990	COG2267	carboxylic ester hydrolase activity
CK207_RS16000	COG0366	Alpha amylase catalytic
CK207_RS16005	COG4989	oxidoreductase activity
CK207_RS16015	COG1136	(ABC) transporter
CK207_RS16015	COG0577	efflux transmembrane transporter activity
CK207_RS16020	COG1136	(ABC) transporter
CK207_RS16020	COG0577	efflux transmembrane transporter activity
CK207_RS16035	COG2972	Histidine kinase
CK207_RS16035	COG0745	RESPONSE REGULATOR receiver
CK207_RS16040	COG3279	Response regulator of the LytR AlgR family
CK207_RS16045	COG4251	negative regulation of phosphorylation
CK207_RS16045	COG3706	GGDEF domain
CK207_RS16045	COG2203	Gaf domain
CK207_RS16045	COG5001	Diguanylate cyclase
CK207_RS16055	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CK207_RS16065	COG3437	response regulator, receiver
CK207_RS16070	COG3850	Histidine kinase
CK207_RS16070	COG2205	protein histidine kinase activity
CK207_RS16070	COG4999	Histidine kinase
CK207_RS16070	COG3437	response regulator, receiver
CK207_RS16080	COG0531	amino acid
CK207_RS16095	COG1151	hydroxylamine reductase activity
CK207_RS16125	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK207_RS16145	COG2433	Pfam Transposase IS66
CK207_RS16155	COG1609	Transcriptional regulator
CK207_RS16160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_RS16180	COG0673	inositol 2-dehydrogenase activity
CK207_RS16185	COG1765	OsmC-like protein
CK207_RS16190	COG0110	maltose O-acetyltransferase activity
CK207_RS16205	COG0583	DNA-binding transcription factor activity
CK207_RS16215	COG0583	DNA-binding transcription factor activity
CK207_RS16220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK207_RS16225	COG3186	Phenylalanine-4-hydroxylase
CK207_RS16230	COG2154	pterin-4-alpha-carbinolamine dehydratase
CK207_RS16235	COG0840	transmembrane signaling receptor activity
CK207_RS16240	COG0534	Mate efflux family protein
CK207_RS16245	COG2207	Transcriptional regulator
CK207_RS16250	COG3437	response regulator, receiver
CK207_RS16250	COG0784	Response regulator, receiver
CK207_RS16260	COG4191	Histidine kinase
CK207_RS16260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK207_RS16270	COG2814	Major facilitator Superfamily
CK207_RS16280	COG2814	Major facilitator Superfamily
CK207_RS16305	COG3240	lipase activity
CK207_RS16315	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CK207_RS16320	COG5380	lipid catabolic process
CK207_RS16350	COG4607	ABC-type enterochelin transport system periplasmic component
CK207_RS16355	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK207_RS16360	COG4605	iron ion homeostasis
CK207_RS16365	COG4604	ABC transporter, ATP-binding protein
CK207_RS16370	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CK207_RS16380	COG3344	reverse transcriptase
CK207_RS16390	COG2814	Major facilitator Superfamily
CK207_RS16415	COG0861	Integral membrane protein TerC family
CK207_RS16430	COG0697	spore germination
CK207_RS16455	COG0509	glycine decarboxylation via glycine cleavage system
CK207_RS16460	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CK207_RS16485	COG0612	Peptidase, M16
CK207_RS16500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK207_RS16500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK207_RS16500	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CK207_RS16505	COG1105	Belongs to the carbohydrate kinase PfkB family
CK207_RS16510	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_RS16510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_RS16515	COG1609	Transcriptional regulator
CK207_RS16520	COG0420	3'-5' exonuclease activity
CK207_RS16525	COG0419	ATPase involved in DNA repair
CK207_RS16530	COG0784	Response regulator, receiver
CK207_RS16530	COG2205	protein histidine kinase activity
CK207_RS16535	COG0156	8-amino-7-oxononanoate synthase activity
CK207_RS16545	COG0038	chloride channel
CK207_RS16550	COG0523	cobalamin synthesis protein
CK207_RS16555	COG1136	(ABC) transporter
CK207_RS16565	COG0577	efflux transmembrane transporter activity
CK207_RS16565	COG1136	(ABC) transporter
CK207_RS16580	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CK207_RS16590	COG3675	Pfam Lipase (class 3)
CK207_RS16600	COG3335	DDE superfamily endonuclease
CK207_RS16640	COG3730	PTS system glucitol sorbitol-specific
CK207_RS16655	COG1028	Short-chain dehydrogenase reductase Sdr
CK207_RS16660	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK207_RS16665	COG1349	DNA-binding transcription factor activity
CK207_RS16670	COG3730	PTS system glucitol sorbitol-specific
CK207_RS16700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK207_RS16705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK207_RS16715	COG3005	denitrification pathway
CK207_RS16725	COG0243	molybdopterin cofactor binding
CK207_RS16735	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CK207_RS16740	COG3850	Histidine kinase
CK207_RS16745	COG2197	response regulator
CK207_RS16750	COG3069	C4-dicarboxylate transmembrane transporter activity
CK207_RS16775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CK207_RS16785	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CK207_RS16790	COG0513	Belongs to the DEAD box helicase family
CK207_RS16840	COG2801	Transposase and inactivated derivatives
CK207_RS16875	COG4682	membrane
CK207_RS16920	COG2433	Pfam Transposase IS66
CK207_RS17010	COG4372	Transposase
CK207_RS17020	COG2433	Pfam Transposase IS66
CK207_RS17060	COG2433	Pfam Transposase IS66
CK207_RS17100	COG0242	peptide deformylase activity
CK207_RS17180	COG2433	Pfam Transposase IS66
CK207_RS17230	COG2433	Pfam Transposase IS66
CK207_RS17310	COG3549	Plasmid maintenance system killer
CK207_RS17315	COG3093	addiction module antidote protein HigA
CK207_RS17325	COG0346	lactoylglutathione lyase activity
CK207_RS17350	COG2433	Pfam Transposase IS66
CK207_RS17370	COG2433	Pfam Transposase IS66
CK207_RS17375	COG2161	toxin-antitoxin pair type II binding
CK207_RS17380	COG4115	mRNA cleavage
CK207_RS17440	COG2433	Pfam Transposase IS66
CK207_RS17455	COG2433	Pfam Transposase IS66
CK207_RS17485	COG0602	queuosine metabolic process
CK207_RS17490	COG1328	CTP reductase activity
CK207_RS17495	COG1328	CTP reductase activity
CK207_RS17515	COG2433	Pfam Transposase IS66
CK207_RS17535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK207_RS17645	COG3335	DDE superfamily endonuclease
CK207_RS17710	COG2433	Pfam Transposase IS66
CK207_RS17765	COG3040	lipid binding
CK207_RS17805	COG0189	ligase activity
CK207_RS17805	COG4067	protein conserved in archaea
CK207_RS17820	COG4166	transmembrane transport
CK207_RS17825	COG4174	ABC transporter (Permease)
CK207_RS17830	COG4239	(ABC) transporter, permease
CK207_RS17835	COG4172	Belongs to the ABC transporter superfamily
CK207_RS17850	COG3038	cytochrome b561
CK207_RS17855	COG2353	YceI-like domain
CK207_RS17860	COG0840	transmembrane signaling receptor activity
CK207_RS17865	COG3335	DDE superfamily endonuclease
CK207_RS17870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CK207_RS17875	COG0545	Peptidyl-prolyl cis-trans isomerase
CK207_RS17890	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CK207_RS17910	COG2897	thiosulfate sulfurtransferase activity
CK207_RS17915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CK207_RS17920	COG0303	'Molybdopterin
CK207_RS17925	COG0302	gtp cyclohydrolase
CK207_RS17930	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CK207_RS17930	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CK207_RS17935	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CK207_RS17940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CK207_RS17945	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CK207_RS17955	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CK207_RS17960	COG1011	Hydrolase
CK207_RS17965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CK207_RS17970	COG2188	Transcriptional regulator
CK207_RS17980	COG3104	oligopeptide transport
CK207_RS17990	COG2116	formate transmembrane transporter activity
CK207_RS17995	COG0583	DNA-binding transcription factor activity
CK207_RS18005	COG3593	DNA synthesis involved in DNA repair
CK207_RS18010	COG0737	Belongs to the 5'-nucleotidase family
CK207_RS18015	COG0861	Integral membrane protein TerC family
CK207_RS18030	COG2824	Alkylphosphonate utilization operon protein PhnA
CK207_RS18040	COG2050	protein possibly involved in aromatic compounds catabolism
CK207_RS18055	COG0488	(ABC) transporter
CK207_RS18075	COG0625	glutathione transferase activity
CK207_RS18080	COG2501	S4 domain
CK207_RS18095	COG0840	transmembrane signaling receptor activity
CK207_RS18105	COG1278	Cold shock
CK207_RS18110	COG3706	GGDEF domain
CK207_RS18115	COG3335	DDE superfamily endonuclease
CK207_RS18135	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CK207_RS18140	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CK207_RS18150	COG0745	RESPONSE REGULATOR receiver
CK207_RS18165	COG3140	Belongs to the UPF0181 family
CK207_RS18170	COG2433	Pfam Transposase IS66
CK207_RS18205	COG2433	Pfam Transposase IS66
CK207_RS18220	COG3328	transposase activity
CK207_RS18235	COG2433	Pfam Transposase IS66
CK207_RS18240	COG3328	transposase activity
CK207_RS18270	COG0583	DNA-binding transcription factor activity
CK207_RS18275	COG1042	CoA-binding domain protein
CK207_RS18275	COG0045	succinate-CoA ligase (ADP-forming) activity
CK207_RS18275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK207_RS18285	COG1181	Belongs to the D-alanine--D-alanine ligase family
CK207_RS18300	COG0023	Translation Initiation Factor
CK207_RS18390	COG3335	DDE superfamily endonuclease
CK207_RS18420	COG2433	Pfam Transposase IS66
CK207_RS18465	COG0724	RNA recognition motif
CK207_RS18480	COG3041	Addiction module toxin RelE StbE family
CK207_RS18500	COG2433	Pfam Transposase IS66
CK207_RS18515	COG3300	MHYT domain
CK207_RS18515	COG5001	Diguanylate cyclase
CK207_RS18525	COG5002	protein histidine kinase activity
CK207_RS18550	COG2203	Gaf domain
CK207_RS18550	COG3706	GGDEF domain
CK207_RS18550	COG4251	negative regulation of phosphorylation
CK207_RS18550	COG5001	Diguanylate cyclase
CK207_RS18560	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CK207_RS18565	COG4149	molybdate abc transporter
CK207_RS18570	COG0725	ABC transporter, periplasmic molybdate-binding protein
CK207_RS18575	COG1492	cobalamin metabolic process
CK207_RS18580	COG3111	PFAM Bacterial OB fold (BOF) protein
CK207_RS18595	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CK207_RS18605	COG2207	Transcriptional regulator
CK207_RS18610	COG1979	alcohol dehydrogenase
CK207_RS18635	COG2271	Major facilitator Superfamily
CK207_RS18640	COG0469	pyruvate kinase activity
CK207_RS18645	COG2205	protein histidine kinase activity
CK207_RS18645	COG0784	Response regulator, receiver
CK207_RS18645	COG2198	Histidine kinase
CK207_RS18650	COG1879	ABC-type sugar transport system periplasmic component
CK207_RS18655	COG1803	Methylglyoxal synthase
CK207_RS18660	COG0210	DNA helicase
CK207_RS18665	COG1289	transmembrane transporter activity
CK207_RS18695	COG5002	protein histidine kinase activity
CK207_RS18695	COG0784	Response regulator, receiver
CK207_RS18710	COG2827	Endonuclease containing a URI domain
CK207_RS18715	COG3132	Protein of unknown function, DUF480
CK207_RS18735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CK207_RS18740	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CK207_RS18745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CK207_RS18750	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CK207_RS18755	COG0247	lactate metabolic process
CK207_RS18760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CK207_RS18765	COG3118	belongs to the thioredoxin family
CK207_RS18785	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CK207_RS18805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK207_RS18810	COG3328	transposase activity
CK207_RS18840	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CK207_RS18855	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CK207_RS18865	COG0513	Belongs to the DEAD box helicase family
CK207_RS18875	COG0814	amino acid
CK207_RS18885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CK207_RS18890	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CK207_RS18900	COG1984	allophanate hydrolase subunit 2
CK207_RS18910	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CK207_RS18915	COG4181	ATPase activity
CK207_RS18925	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CK207_RS18930	COG5001	Diguanylate cyclase
CK207_RS18930	COG1716	ATPase activity
CK207_RS18940	COG0484	heat shock protein binding
CK207_RS18975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK207_RS18980	COG5001	Diguanylate cyclase
CK207_RS18980	COG3300	MHYT domain
CK207_RS19000	COG0010	Belongs to the arginase family
CK207_RS19005	COG1166	arginine decarboxylase activity
CK207_RS19020	COG4176	ABC-type proline glycine betaine transport system permease component
CK207_RS19025	COG3344	reverse transcriptase
CK207_RS19030	COG2113	Glycine betaine
CK207_RS19050	COG0527	aspartate kinase activity
CK207_RS19055	COG0662	Cupin 2, conserved barrel domain protein
CK207_RS19060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CK207_RS19065	COG0456	acetyltransferase
CK207_RS19075	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CK207_RS19080	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CK207_RS19110	COG3335	DDE superfamily endonuclease
CK207_RS19120	COG0366	Alpha amylase catalytic
CK207_RS19140	COG0714	Associated with various cellular activities
CK207_RS19160	COG2304	oxidoreductase activity
CK207_RS19175	COG3706	GGDEF domain
CK207_RS19190	COG3530	Putative quorum-sensing-regulated virulence factor
CK207_RS19195	COG1368	sulfuric ester hydrolase activity
CK207_RS19205	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CK207_RS19245	COG1063	alcohol dehydrogenase
CK207_RS19250	COG0156	8-amino-7-oxononanoate synthase activity
CK207_RS19260	COG0346	lactoylglutathione lyase activity
CK207_RS19275	COG2197	response regulator
CK207_RS19280	COG3851	Histidine kinase
CK207_RS19285	COG2271	Major facilitator Superfamily
CK207_RS19295	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CK207_RS19320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CK207_RS19325	COG0640	Transcriptional regulator
CK207_RS19330	COG0798	PFAM Bile acid sodium symporter
CK207_RS19335	COG0640	Transcriptional regulator
CK207_RS19340	COG0659	secondary active sulfate transmembrane transporter activity
CK207_RS19345	COG0589	response to stress
CK207_RS19370	COG4977	sequence-specific DNA binding
CK207_RS19370	COG1917	Cupin 2, conserved barrel domain protein
CK207_RS19375	COG4771	TonB-dependent receptor
CK207_RS19380	COG2814	Major facilitator Superfamily
CK207_RS19385	COG3433	isochorismatase activity
CK207_RS19385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK207_RS19385	COG2226	methyltransferase
CK207_RS19410	COG1021	2,3-dihydroxybenzoate-AMP ligase
CK207_RS19415	COG1132	(ABC) transporter
CK207_RS19420	COG1132	(ABC) transporter
CK207_RS19455	COG0714	Associated with various cellular activities
CK207_RS19490	COG2433	Pfam Transposase IS66
CK207_RS19515	COG3335	DDE superfamily endonuclease
CK207_RS19520	COG1196	nuclear chromosome segregation
CK207_RS19525	COG0732	type I restriction modification DNA specificity domain
CK207_RS19530	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CK207_RS19540	COG2204	response regulator
CK207_RS19595	COG3501	Rhs element vgr protein
CK207_RS19645	COG0516	GMP reductase activity
CK207_RS19650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CK207_RS19675	COG1278	Cold shock
CK207_RS19680	COG4681	YaeQ
CK207_RS19685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK207_RS19685	COG1017	nitric oxide dioxygenase activity
CK207_RS19690	COG3604	Transcriptional regulator
CK207_RS19705	COG2195	Cleaves the N-terminal amino acid of tripeptides
CK207_RS19710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CK207_RS19715	COG3217	Mosc domain protein beta barrel domain protein
CK207_RS19715	COG0633	Ferredoxin
CK207_RS19720	COG0418	dihydroorotase activity
CK207_RS19725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CK207_RS19730	COG2354	Protein conserved in bacteria
CK207_RS19750	COG2199	diguanylate cyclase activity
CK207_RS19755	COG1349	DNA-binding transcription factor activity
CK207_RS19780	COG3833	ABC-type maltose transport systems, permease component
CK207_RS19785	COG1175	transmembrane transport
CK207_RS19800	COG3842	ATPase activity
CK207_RS19810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK207_RS19815	COG0784	Response regulator, receiver
CK207_RS19815	COG0835	chemotaxis
CK207_RS19820	COG2315	Protein conserved in bacteria
CK207_RS19825	COG3335	DDE superfamily endonuclease
CK207_RS19830	COG3706	GGDEF domain
CK207_RS19865	COG5001	Diguanylate cyclase
CK207_RS19875	COG1741	Belongs to the pirin family
CK207_RS19885	COG3123	guanosine phosphorylase activity
CK207_RS19895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CK207_RS19905	COG0765	amino acid transport
CK207_RS19910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK207_RS19915	COG0765	amino acid transport
CK207_RS19920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CK207_RS19940	COG0179	Fumarylacetoacetate (FAA) hydrolase
CK207_RS19950	COG0697	spore germination
CK207_RS19970	COG2814	Major facilitator Superfamily
CK207_RS19975	COG0583	DNA-binding transcription factor activity
CK207_RS19980	COG5001	Diguanylate cyclase
CK207_RS19985	COG0739	heme binding
CK207_RS19995	COG0659	secondary active sulfate transmembrane transporter activity
CK207_RS20000	COG3314	Sporulation integral membrane protein YlbJ
CK207_RS20020	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CK207_RS20025	COG0581	inorganic phosphate transmembrane transporter activity
CK207_RS20030	COG0573	inorganic phosphate transmembrane transporter activity
CK207_RS20035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CK207_RS20045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK207_RS20050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CK207_RS20090	COG2271	Major facilitator Superfamily
CK207_RS20095	COG0584	glycerophosphoryl diester phosphodiesterase
CK207_RS20105	COG3527	Alpha-acetolactate decarboxylase
CK207_RS20130	COG0583	DNA-binding transcription factor activity
CK207_RS20135	COG1620	l-lactate permease
CK207_RS20155	COG1881	PFAM PEBP family protein
CK207_RS20170	COG1230	cation diffusion facilitator family transporter
CK207_RS20175	COG3122	Protein conserved in bacteria
CK207_RS20200	COG3335	DDE superfamily endonuclease
CK207_RS20210	COG0840	transmembrane signaling receptor activity
CK207_RS20220	COG1472	Belongs to the glycosyl hydrolase 3 family
CK207_RS20225	COG3842	ATPase activity
CK207_RS20245	COG2211	Major facilitator Superfamily
CK207_RS20255	COG1067	ATP-dependent peptidase activity
CK207_RS20265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CK207_RS20270	COG0363	glucosamine-6-phosphate deaminase activity
CK207_RS20280	COG0583	DNA-binding transcription factor activity
CK207_RS20295	COG1609	Transcriptional regulator
CK207_RS20300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK207_RS20305	COG1879	ABC-type sugar transport system periplasmic component
CK207_RS20310	COG1172	Belongs to the binding-protein-dependent transport system permease family
CK207_RS20315	COG1129	ABC transporter
CK207_RS20320	COG1869	D-ribose catabolic process
CK207_RS20335	COG2433	Pfam Transposase IS66
CK207_RS20375	COG3501	Rhs element vgr protein
CK207_RS20385	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CK207_RS20390	COG1640	4-alpha-glucanotransferase
CK207_RS20395	COG0058	SHG alpha-glucan phosphorylase activity
CK207_RS20400	COG2909	trisaccharide binding
CK207_RS20420	COG0840	transmembrane signaling receptor activity
CK207_RS20425	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CK207_RS20450	COG3335	DDE superfamily endonuclease
CK207_RS20490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CK207_RS20500	COG0259	pyridoxamine-phosphate oxidase activity
CK207_RS20550	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CK207_RS20555	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CK207_RS20560	COG0840	transmembrane signaling receptor activity
CK207_RS20570	COG0835	chemotaxis
CK207_RS20580	COG0745	RESPONSE REGULATOR receiver
CK207_RS20590	COG1444	tRNA N-acetyltransferase activity
CK207_RS20595	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CK207_RS20675	COG1715	Restriction endonuclease