locus-tag	class	description
A6A12_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A6A12_RS00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A6A12_RS00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6A12_RS00035	ENOG4108ZNX	Heat shock protein
A6A12_RS00040	ENOG4105JKW	Valine--pyruvate aminotransferase
A6A12_RS00045	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
A6A12_RS00050	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
A6A12_RS00080	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
A6A12_RS00085	ENOG4105C7B	Threonine dehydratase
A6A12_RS00095	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A6A12_RS00100	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
A6A12_RS00110	ENOG4105C0P	Mg chelatase subunit ChlI
A6A12_RS00205	ENOG4108Z33	Thiol disulfide Interchange Protein
A6A12_RS00210	ENOG4105E27	serine threonine protein kinase
A6A12_RS00225	ENOG4105PC1	Conserved Protein
A6A12_RS00235	ENOG4108UT2	hemolysin iii
A6A12_RS00245	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A6A12_RS00250	ENOG4105C1A	potassium transporter peripheral membrane
A6A12_RS00255	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A6A12_RS00260	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
A6A12_RS00270	ENOG4108WZM	domain protein
A6A12_RS00275	ENOG4105C79	DNA protecting protein DprA
A6A12_RS00280	ENOG4108RPN	Protein smg homolog
A6A12_RS00285	ENOG4108WI1	Dna topoisomerase
A6A12_RS00290	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
A6A12_RS00295	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A6A12_RS00300	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A6A12_RS00305	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
A6A12_RS00310	ENOG4105E2X	shikimate dehydrogenase
A6A12_RS00315	ENOG4105SG3	Protein of unknown function (DUF1488)
A6A12_RS00320	ENOG4108Z0R	Transferase
A6A12_RS00355	ENOG410601J	HemY protein
A6A12_RS00360	ENOG4105ECF	c-methyltransferase
A6A12_RS00365	ENOG41076E6	Uroporphyrinogen-III Synthase
A6A12_RS00370	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
A6A12_RS00375	ENOG4107T0K	Adenylate cyclase
A6A12_RS00380	ENOG4105XQ6	frataxin-like protein
A6A12_RS00390	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A6A12_RS00405	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A6A12_RS00410	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
A6A12_RS00415	ENOG4106IUH	DTW domain containing protein
A6A12_RS00425	ENOG4105DQF	Hydrolase
A6A12_RS00430	ENOG4108EUD	Lysophospholipase
A6A12_RS00435	ENOG410829K	Lysine exporter protein (Lyse ygga)
A6A12_RS00440	ENOG4105D58	Diguanylate phosphodiesterase
A6A12_RS00445	ENOG4108RMU	ferritin dps family protein
A6A12_RS00475	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
A6A12_RS00535	ENOG4106H78	methyltransferase
A6A12_RS00540	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A6A12_RS00545	ENOG4105CAK	Cell division ATP-binding protein ftsE
A6A12_RS00550	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
A6A12_RS00555	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6A12_RS00560	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
A6A12_RS00565	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
A6A12_RS00570	ENOG4105X6C	Flagellar basal body-associated protein FliL
A6A12_RS00575	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
A6A12_RS00580	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
A6A12_RS00585	ENOG4105E55	glycerol-3-phosphate acyltransferase
A6A12_RS00600	ENOG4107R73	Mate efflux family protein
A6A12_RS00605	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
A6A12_RS00615	ENOG4108Y73	Membrane
A6A12_RS00635	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
A6A12_RS00660	ENOG4108C33	Resolvase
A6A12_RS00700	ENOG4105CAF	HipA N-terminal domain protein
A6A12_RS00735	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A6A12_RS00745	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A6A12_RS00785	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
A6A12_RS00790	ENOG4105BZU	Histidine kinase
A6A12_RS00795	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6A12_RS00800	ENOG4105CUX	Signal transduction histidine kinase
A6A12_RS00810	ENOG4105C5F	glutamine synthetase
A6A12_RS00815	ENOG4105CI3	gtp-binding protein typa
A6A12_RS00820	ENOG4107S2Z	UPF0761 membrane protein
A6A12_RS00825	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
A6A12_RS00830	ENOG4105SUU	thioesterase domain
A6A12_RS00840	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
A6A12_RS00845	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
A6A12_RS00850	ENOG4105VEJ	Heat shock protein
A6A12_RS00855	ENOG4108XKW	General secretion pathway protein C
A6A12_RS00865	ENOG4107QHF	type ii secretion system protein e
A6A12_RS00870	ENOG4105D7Q	type ii secretion system
A6A12_RS00875	ENOG4108VAU	general secretion pathway protein G
A6A12_RS00880	ENOG4105VWV	general secretion pathway protein h
A6A12_RS00885	ENOG4105X5Z	General secretion pathway protein I
A6A12_RS00890	ENOG4108WWZ	General secretion pathway protein J
A6A12_RS00895	ENOG4108RTD	type II secretion system protein K
A6A12_RS00900	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
A6A12_RS00905	ENOG4105U1E	general secretion pathway protein M
A6A12_RS00915	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
A6A12_RS00920	ENOG4107RK2	ADP-ribose diphosphatase NudE
A6A12_RS00925	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
A6A12_RS00930	ENOG4105MJ2	Competence protein
A6A12_RS00945	ENOG4105BZM	domain protein
A6A12_RS00950	ENOG4108RRZ	Transcription elongation factor GreB
A6A12_RS00960	ENOG4105RA2	Membrane
A6A12_RS00970	ENOG4105ETT	transcriptional Regulator, LysR family
A6A12_RS00980	ENOG4108RCM	Nitroreductase
A6A12_RS01000	ENOG4105E0F	Histidine kinase
A6A12_RS01005	ENOG4105C2W	permease
A6A12_RS01010	ENOG4105CB5	ATP-dependent DNA helicase recG
A6A12_RS01015	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A6A12_RS01020	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
A6A12_RS01025	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A6A12_RS01030	ENOG4105EX9	Membrane
A6A12_RS01035	ENOG4105C9X	ppx gppa phosphatase
A6A12_RS01040	ENOG4105C1J	atp-dependent rna helicase
A6A12_RS01050	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
A6A12_RS01060	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A6A12_RS01070	ENOG4107QK7	reductase
A6A12_RS01105	ENOG4105JIM	Phosphatidylserine synthase
A6A12_RS01115	ENOG4105D4A	Cell wall formation (By similarity)
A6A12_RS01120	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A6A12_RS01125	ENOG4105CS9	pantothenic acid kinase
A6A12_RS01155	ENOG4105PM1	preprotein translocase subunit SecE
A6A12_RS01160	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A6A12_RS01165	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A6A12_RS01175	ENOG4108VZM	50s ribosomal protein L10
A6A12_RS01180	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A6A12_RS01185	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A6A12_RS01190	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A6A12_RS01195	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
A6A12_RS01200	ENOG4105E09	nadh pyrophosphatase
A6A12_RS01210	ENOG41062JF	Transcriptional regulator
A6A12_RS01220	ENOG41063SB	peptidase
A6A12_RS01225	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A6A12_RS01235	ENOG4105C8Q	Methyl-accepting chemotaxis
A6A12_RS01240	ENOG4107QWE	)-transporter
A6A12_RS01245	ENOG4105DJ4	phosphatidylserine decarboxylase
A6A12_RS01250	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A6A12_RS01255	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
A6A12_RS01275	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
A6A12_RS01280	ENOG4105K8N	protein family UPF0079, ATPase
A6A12_RS01285	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A6A12_RS01290	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
A6A12_RS01295	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
A6A12_RS01305	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A6A12_RS01310	ENOG4107QJR	hflk protein
A6A12_RS01315	ENOG4105EPW	hflc protein
A6A12_RS01325	ENOG41069P5	Protein slyX homolog
A6A12_RS01335	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A6A12_RS01340	ENOG4105WWK	YheO domain protein
A6A12_RS01345	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
A6A12_RS01350	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
A6A12_RS01360	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A6A12_RS01365	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A6A12_RS01375	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A6A12_RS01380	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
A6A12_RS01385	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
A6A12_RS01390	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
A6A12_RS01395	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A6A12_RS01405	ENOG4105CDU	Replicative dna helicase
A6A12_RS01410	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A6A12_RS01415	ENOG4107QP8	phosphohexose isomerase
A6A12_RS01440	ENOG4105MYN	Zinc uptake regulation protein
A6A12_RS01445	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A6A12_RS01465	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
A6A12_RS01475	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
A6A12_RS01510	ENOG4105EEQ	Na H antiporter
A6A12_RS01515	ENOG4105C3R	Methionine synthase
A6A12_RS01520	ENOG4105CFH	Aspartokinase
A6A12_RS01525	ENOG4105C5R	Aminotransferase
A6A12_RS01540	ENOG4105CJW	magnesium transporter
A6A12_RS01555	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A6A12_RS01560	ENOG41086KC	Transcriptional regulator
A6A12_RS01565	ENOG4108UUM	single-stranded DNA-binding protein
A6A12_RS01570	ENOG41062P1	Diguanylate cyclase phosphodiesterase
A6A12_RS01605	ENOG4107QHF	type ii secretion system protein e
A6A12_RS01610	ENOG4105D7Q	type ii secretion system
A6A12_RS01660	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
A6A12_RS01665	ENOG4105VQ7	Rod shape-determining protein MreD
A6A12_RS01670	ENOG4108Z03	MAF-like protein
A6A12_RS01675	ENOG4105C03	ribonuclease
A6A12_RS01680	ENOG4105QD6	exported protein
A6A12_RS01690	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A6A12_RS01695	ENOG4105CEU	Arginine dihydrolase
A6A12_RS01715	ENOG41081QV	Universal stress protein
A6A12_RS01725	ENOG4105H1G	trap transporter solute receptor taxi family
A6A12_RS01735	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
A6A12_RS01740	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A6A12_RS01745	ENOG4105D5Q	Arginine ornithine antiporter
A6A12_RS01750	ENOG4105EAH	synthase
A6A12_RS01760	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
A6A12_RS01765	ENOG4105K46	50S ribosomal protein l27
A6A12_RS01770	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A6A12_RS01775	ENOG4105DWK	Membrane
A6A12_RS01780	ENOG4107XM3	UPF0442 protein
A6A12_RS01790	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
A6A12_RS01795	ENOG4105NWN	ApaG protein
A6A12_RS01805	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
A6A12_RS01810	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
A6A12_RS01815	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
A6A12_RS01820	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
A6A12_RS01870	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
A6A12_RS01880	ENOG4105CEN	a g-specific adenine glycosylase
A6A12_RS01890	ENOG4105CSV	Glutaminase
A6A12_RS01895	ENOG4105CSA	Coproporphyrinogen iii oxidase
A6A12_RS01910	ENOG4105VZ9	UPF0235 protein
A6A12_RS01915	ENOG4108VIA	integral membrane protein
A6A12_RS01920	ENOG4105II7	pyrroline-5-carboxylate reductase
A6A12_RS01925	ENOG4105DFA	alanine racemase domain protein
A6A12_RS01930	ENOG4105CZX	twitching motility protein
A6A12_RS01935	ENOG4105CZX	twitching motility protein
A6A12_RS01945	ENOG4108UJU	UPF0301 protein
A6A12_RS01950	ENOG4105D7Z	glutathione synthase
A6A12_RS01955	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
A6A12_RS01960	ENOG4105RWS	endonuclease I
A6A12_RS01970	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
A6A12_RS01980	ENOG4108R4R	Iron-regulated virulence regulatory protein
A6A12_RS01985	ENOG4105D05	Receptor
A6A12_RS01990	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A6A12_RS01995	ENOG4105BZA	Phosphoglycerate kinase
A6A12_RS02005	ENOG4105D2N	Aldolase
A6A12_RS02010	ENOG4105D64	Mechanosensitive ion channel
A6A12_RS02015	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
A6A12_RS02020	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
A6A12_RS02030	ENOG4105BZU	Histidine kinase
A6A12_RS02035	ENOG4105CA9	Pyruvate kinase
A6A12_RS02040	ENOG410804X	Transcriptional regulator
A6A12_RS02045	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A6A12_RS02050	ENOG4107VGF	ig domain protein group 2 domain protein
A6A12_RS02060	ENOG4108YZN	class I peptide chain release factor
A6A12_RS02065	ENOG4108WC9	type VI secretion system effector, hcp1 family
A6A12_RS02070	ENOG4105CS6	Rhs element vgr protein
A6A12_RS02170	ENOG4106K8T	Toxic component of a toxin-antitoxin (TA) module. A stable (half-life 27.6 minutes) endoribonuclease that in the absence of cognate antitoxin RnlB causes generalized RNA degradation. Degrades late enterobacteria phage T4 mRNAs, protecting the host against T4 reproduction. Activity is inhibited by cognate antitoxin RnlB and by enterobacteria phage T4 protein Dmd. Targets cyaA mRNA
A6A12_RS02175	ENOG4106BHJ	Antitoxin component of a toxin-antitoxin (TA) module. A labile antitoxin (half-life of 2.1 minutes) that inhibits the endonuclease activity of cognate toxin RnlA but not that of non- cognate toxin LsoA
A6A12_RS02220	ENOG4105F5W	AtP-binding protein
A6A12_RS02225	ENOG4105D70	Integrase catalytic subunit
A6A12_RS02295	ENOG4105C4R	Atp-dependent dna helicase
A6A12_RS02315	ENOG4105CAF	HipA N-terminal domain protein
A6A12_RS02330	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6A12_RS02335	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A6A12_RS02340	ENOG4105KTH	gatB Yqey
A6A12_RS02345	ENOG4105VCC	30S ribosomal protein S21
A6A12_RS02350	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A6A12_RS02360	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
A6A12_RS02365	ENOG4107ZVW	dihydroneopterin aldolase
A6A12_RS02370	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A6A12_RS02375	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A6A12_RS02380	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
A6A12_RS02385	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
A6A12_RS02390	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
A6A12_RS02395	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
A6A12_RS02400	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A6A12_RS02405	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A6A12_RS02410	ENOG4108K5P	(LipO)protein
A6A12_RS02415	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6A12_RS02420	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A6A12_RS02425	ENOG4105C6T	cysteine synthase
A6A12_RS02430	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
A6A12_RS02435	ENOG4108I5D	sulfate abc transporter
A6A12_RS02440	ENOG4105ECW	sulfate abc transporter
A6A12_RS02445	ENOG4108IJ6	ABC transporter
A6A12_RS02450	ENOG4107TH8	cina domain protein
A6A12_RS02455	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A6A12_RS02460	ENOG4105Y3E	Modulates RecA activity (By similarity)
A6A12_RS02465	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A6A12_RS02470	ENOG4105CFH	Aspartokinase
A6A12_RS02475	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
A6A12_RS02510	ENOG4107QSA	Oxaloacetate decarboxylase
A6A12_RS02515	ENOG4105D9Q	decarboxylase (Beta subunit)
A6A12_RS02520	ENOG4105CPQ	Dehydrogenase
A6A12_RS02525	ENOG4105W39	Membrane
A6A12_RS02535	ENOG4105D9M	gamma-glutamylcysteine synthetase
A6A12_RS02540	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
A6A12_RS02545	ENOG4108JU6	CBS domain protein
A6A12_RS02550	ENOG4106KVJ	cytochrome C assembly protein
A6A12_RS02555	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A6A12_RS02560	ENOG4105K5M	30s ribosomal protein S16
A6A12_RS02565	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A6A12_RS02575	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A6A12_RS02585	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
A6A12_RS02590	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A6A12_RS02595	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
A6A12_RS02600	ENOG4105D7Q	type ii secretion system
A6A12_RS02605	ENOG4107QHF	type ii secretion system protein e
A6A12_RS02610	ENOG4105X0D	Fimbrial protein
A6A12_RS02615	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A6A12_RS02625	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
A6A12_RS02630	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A6A12_RS02635	ENOG4105T95	Thiol disulfide interChange protein
A6A12_RS02640	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A6A12_RS02645	ENOG41073TP	transcriptional regulator
A6A12_RS02650	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
A6A12_RS02655	ENOG4107QSN	dihydrolipoamide acetyltransferase
A6A12_RS02660	ENOG4107QN2	dihydrolipoyl dehydrogenase
A6A12_RS02665	ENOG410630P	Transcriptional regulator
A6A12_RS02670	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A6A12_RS02675	ENOG41077A9	carbonic anhydrase
A6A12_RS02680	ENOG4105CHH	sulfate transporter
A6A12_RS02685	ENOG4105DA5	(ABC) transporter
A6A12_RS02690	ENOG4105E3A	(ABC) transporter
A6A12_RS02700	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
A6A12_RS02705	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A6A12_RS02710	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A6A12_RS02715	ENOG4105DJ0	Poly(A) Polymerase
A6A12_RS02720	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
A6A12_RS02730	ENOG4105PW4	Sugar fermentation stimulation protein homolog
A6A12_RS02735	ENOG4105CQ7	ATP-dependent helicase
A6A12_RS02740	ENOG4105BZ4	penicillin-binding protein
A6A12_RS02745	ENOG4105D78	K07001 NTE family protein
A6A12_RS02750	ENOG4107QIJ	Aconitate hydratase 2
A6A12_RS02755	ENOG4105BZW	Glycerate kinase
A6A12_RS02760	ENOG4107QQ0	gntp family
A6A12_RS02765	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
A6A12_RS02775	ENOG4108YZA	Nitrogen regulatory protein pii
A6A12_RS02800	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A6A12_RS02810	ENOG4105E2D	ec 3.2.1.52
A6A12_RS02815	ENOG4105RD7	BadF BadG BcrA BcrD
A6A12_RS02825	ENOG4108JQ7	(ABC) transporter
A6A12_RS02830	ENOG4105C3U	ABC transporter
A6A12_RS02835	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A6A12_RS02855	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
A6A12_RS02860	ENOG4105IPI	Membrane
A6A12_RS02865	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
A6A12_RS02870	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
A6A12_RS02885	ENOG4105DR5	peptidase
A6A12_RS02890	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A6A12_RS02900	ENOG4105CJW	magnesium transporter
A6A12_RS02905	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
A6A12_RS02910	ENOG4105FCK	Membrane
A6A12_RS02915	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A6A12_RS02920	ENOG4105HBR	Rna-binding protein
A6A12_RS02930	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A6A12_RS02935	ENOG4105EEI	dihydropteroate synthase
A6A12_RS02945	ENOG4105NTZ	Preprotein translocase subunit SecG
A6A12_RS02960	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
A6A12_RS02965	ENOG4105CHV	Transcription elongation factor NusA
A6A12_RS02970	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A6A12_RS02975	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A6A12_RS02980	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A6A12_RS02990	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A6A12_RS03000	ENOG41062A4	Transcriptional regulator
A6A12_RS03020	ENOG4105BZU	Histidine kinase
A6A12_RS03030	ENOG4108YYD	acetyltransferase
A6A12_RS03040	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
A6A12_RS03045	ENOG4105BZU	Histidine kinase
A6A12_RS03050	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
A6A12_RS03055	ENOG4105C1J	atp-dependent rna helicase
A6A12_RS03065	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
A6A12_RS03075	ENOG4105CRK	lysyL-tRNA synthetase
A6A12_RS03080	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6A12_RS03090	ENOG4105CPC	Aldo Keto reductase
A6A12_RS03100	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
A6A12_RS03105	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
A6A12_RS03110	ENOG4105HF0	Membrane
A6A12_RS03115	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A6A12_RS03120	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
A6A12_RS03155	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
A6A12_RS03170	ENOG41063Z6	transcriptional regulator, lysR family
A6A12_RS03175	ENOG41080HT	Transcriptional regulator, arsr family
A6A12_RS03185	ENOG4105CJR	Integral membrane protein (MviN
A6A12_RS03190	ENOG4105DTN	riboflavin biosynthesis protein ribF
A6A12_RS03195	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A6A12_RS03200	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A6A12_RS03205	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
A6A12_RS03230	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A6A12_RS03235	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
A6A12_RS03245	ENOG4108NEV	two component transcriptional regulator, LytTR family
A6A12_RS03250	ENOG4108HRK	Histidine kinase
A6A12_RS03255	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A6A12_RS03270	ENOG4105C5H	ABC transporter
A6A12_RS03275	ENOG4107SC1	transglycosylase
A6A12_RS03280	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
A6A12_RS03285	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A6A12_RS03290	ENOG4108K0B	C-di-gmp phosphodiesterase
A6A12_RS03295	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
A6A12_RS03305	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
A6A12_RS03310	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A6A12_RS03315	ENOG4105C34	Pseudouridine synthase
A6A12_RS03320	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A6A12_RS03325	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A6A12_RS03370	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
A6A12_RS03375	ENOG4105CFP	Peptidase U32
A6A12_RS03380	ENOG4105DH7	May be involved in recombination (By similarity)
A6A12_RS03385	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A6A12_RS03390	ENOG4105BZU	Histidine kinase
A6A12_RS03395	ENOG4105DJH	phosphate
A6A12_RS03400	ENOG4105C9X	ppx gppa phosphatase
A6A12_RS03405	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
A6A12_RS03410	ENOG4105C8U	phosphate abc transporter
A6A12_RS03415	ENOG4105E2Z	phosphate ABC transporter (Permease
A6A12_RS03420	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A6A12_RS03435	ENOG4105D3R	alkyl hydroperoxide reductase
A6A12_RS03440	ENOG4105C5Q	Transcriptional regulator
A6A12_RS03445	ENOG4107QP3	malate synthase g
A6A12_RS03450	ENOG4108I9X	Isocitrate lyase
A6A12_RS03455	ENOG4105W87	Cbs domain
A6A12_RS03470	ENOG4105VIE	preprotein translocase, subunit YajC
A6A12_RS03475	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A6A12_RS03480	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A6A12_RS03485	ENOG4105ECY	inositol monophosphatase
A6A12_RS03490	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
A6A12_RS03495	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
A6A12_RS03500	ENOG4105C3J	Cysteine desulfurase
A6A12_RS03505	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
A6A12_RS03510	ENOG4108Z4V	iron-sulfur cluster assembly
A6A12_RS03515	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
A6A12_RS03520	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
A6A12_RS03525	ENOG4108ZIT	Ferredoxin, 2FE-2S
A6A12_RS03530	ENOG4105WVQ	Fe-S assembly protein IscX
A6A12_RS03535	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A6A12_RS03540	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A6A12_RS03550	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
A6A12_RS03555	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
A6A12_RS03560	ENOG4105CUT	histidyl-tRNA synthetase
A6A12_RS03565	ENOG4105N21	Membrane
A6A12_RS03570	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A6A12_RS03575	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A6A12_RS03585	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A6A12_RS03590	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A6A12_RS03595	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A6A12_RS03600	ENOG4105DWF	phosphomethylpyrimidine kinase
A6A12_RS03610	ENOG4106HK8	GPR1 FUN34 yaaH family protein
A6A12_RS03615	ENOG4105BZG	amino acid carrier protein
A6A12_RS03630	ENOG4105C94	Transporter
A6A12_RS03660	ENOG41069H0	dihydroorotase EC 3.5.2.3
A6A12_RS03735	ENOG4105JXR	Protein of unknown function (DUF3296)
A6A12_RS03805	ENOG4108YGG	dna repair protein
A6A12_RS03820	ENOG4106H3A	restriction
A6A12_RS03825	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
A6A12_RS03845	ENOG4105CVR	type I restriction-modification system
A6A12_RS03850	ENOG4105DFP	Integrase
A6A12_RS03860	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
A6A12_RS03865	ENOG4108Z1B	Cyclase dehydrase
A6A12_RS03870	ENOG4105VDB	UPF0125 protein
A6A12_RS03875	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A6A12_RS03880	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A6A12_RS03890	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A6A12_RS03905	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A6A12_RS03935	ENOG4105CFC	Transporter
A6A12_RS03940	ENOG4105C4W	S-formylglutathione hydrolase
A6A12_RS03950	ENOG4105CC0	LysR family Transcriptional regulator
A6A12_RS03955	ENOG4108Z6B	deaminase
A6A12_RS03960	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
A6A12_RS03970	ENOG4108ETH	Formylglycinamide ribotide synthetase
A6A12_RS03985	ENOG4105W1I	UPF0253 protein
A6A12_RS03990	ENOG4108Q2J	Inner membrane protein YebE
A6A12_RS03995	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A6A12_RS04000	ENOG4108R96	Methyltransferase, YaeB family
A6A12_RS04015	ENOG4108UPT	UPF0178 protein
A6A12_RS04040	ENOG4105WP7	tRNA pseudouridine synthase C
A6A12_RS04045	ENOG4105DR9	pseudouridine synthase
A6A12_RS04050	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A6A12_RS04055	ENOG4105CTB	Polyprenyl synthetase
A6A12_RS04065	ENOG4105E14	MotA TolQ exbB proton channel
A6A12_RS04075	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A6A12_RS04080	ENOG4105ETT	transcriptional Regulator, LysR family
A6A12_RS04085	ENOG4105M08	Membrane
A6A12_RS04090	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
A6A12_RS04095	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
A6A12_RS04100	ENOG4105EWT	decarboxylase family
A6A12_RS04105	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
A6A12_RS04115	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
A6A12_RS04120	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
A6A12_RS04125	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
A6A12_RS04130	ENOG4105D01	(LipO)protein
A6A12_RS04135	ENOG4108UMI	ABC transporter, permease
A6A12_RS04145	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
A6A12_RS04155	ENOG4105D4X	repressor
A6A12_RS04160	ENOG4105C5Y	PTS System
A6A12_RS04165	ENOG4105CG3	alpha amylase, catalytic region
A6A12_RS04170	ENOG4107EXC	regulatoR
A6A12_RS04175	ENOG4105JJR	Histidine kinase
A6A12_RS04200	ENOG410624X	efflux transporter, rnd family, mfp subunit
A6A12_RS04205	ENOG4105BZS	acriflavin resistance protein
A6A12_RS04210	ENOG4105KJF	protein tyrosine phosphatase
A6A12_RS04215	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A6A12_RS04225	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A6A12_RS04260	ENOG4105D7W	serine acetyltransferase
A6A12_RS04270	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
A6A12_RS04275	ENOG4108MA4	Peptidase M66
A6A12_RS04300	ENOG4108QV3	biosynthesis protein
A6A12_RS04305	ENOG4105DAY	polysaccharide export protein
A6A12_RS04335	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A6A12_RS04345	ENOG4108Z43	UPF0250 protein
A6A12_RS04350	ENOG4105DZ1	carboxypeptidase
A6A12_RS04355	ENOG4105K6T	rare lipoprotein A
A6A12_RS04360	ENOG4105CNI	cell division protein FtsW
A6A12_RS04365	ENOG4105CJN	penicillin-binding protein
A6A12_RS04370	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
A6A12_RS04375	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
A6A12_RS04380	ENOG4105DJF	DNA polymerase III, delta' subunit
A6A12_RS04385	ENOG4108U2H	Rare lipoprotein B
A6A12_RS04390	ENOG4105C8T	Leucyl-tRNA synthetase
A6A12_RS04395	ENOG4107PAI	alpha helical protein
A6A12_RS04400	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A6A12_RS04405	ENOG4108JU5	Magnesium and cobalt efflux protein
A6A12_RS04410	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
A6A12_RS04415	ENOG4105C9A	Phoh family
A6A12_RS04420	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A6A12_RS04425	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A6A12_RS04430	ENOG4105C5Y	PTS System
A6A12_RS04435	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
A6A12_RS04440	ENOG4105KZ7	phosphocarrier protein hpr
A6A12_RS04445	ENOG4105C6T	cysteine synthase
A6A12_RS04450	ENOG4105EXN	Sulfate transport protein CysZ
A6A12_RS04455	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
A6A12_RS04460	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A6A12_RS04465	ENOG41081QG	Porin Gram-negative type
A6A12_RS04475	ENOG410607W	Transposase
A6A12_RS04480	ENOG4108Z6Z	Transcriptional regulator
A6A12_RS04490	ENOG4107QX8	SPFH domain, Band 7 family protein
A6A12_RS04495	ENOG4107QR8	Thioredoxin
A6A12_RS04500	ENOG4105ECP	epimerase
A6A12_RS04505	ENOG4108RE9	Phosphodiesterase
A6A12_RS04520	ENOG4108DQ1	activator toxR
A6A12_RS04525	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
A6A12_RS04530	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A6A12_RS04535	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
A6A12_RS04540	ENOG4105DUX	Transporter
A6A12_RS04545	ENOG4105MDZ	Transcriptional activator rfaH
A6A12_RS04550	ENOG4105CAQ	asparagine synthetase
A6A12_RS04555	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A6A12_RS04560	ENOG4105E2R	ROK family
A6A12_RS04565	ENOG4105CE4	GlcNAc 6-P deacetylase
A6A12_RS04570	ENOG4105CI1	PTS System
A6A12_RS04575	ENOG4105CX6	glutaminyL-tRNA synthetase
A6A12_RS04585	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A6A12_RS04595	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A6A12_RS04600	ENOG4108S3P	Sporulation domain protein
A6A12_RS04605	ENOG4105E96	Colicin v production protein
A6A12_RS04610	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
A6A12_RS04615	ENOG4105D3Y	Na H antiporter
A6A12_RS04620	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
A6A12_RS04625	ENOG4105EIY	sodium-type flagellar protein motY
A6A12_RS04630	ENOG4108UYE	Lactoylglutathione lyase
A6A12_RS04635	ENOG4105CSM	endonuclease III
A6A12_RS04640	ENOG4105DZB	Electron transport complex
A6A12_RS04645	ENOG4108UQQ	Electron transport complex
A6A12_RS04650	ENOG4105D6A	Electron transport complex
A6A12_RS04660	ENOG4108R3D	Electron transport complex
A6A12_RS04675	ENOG4107RBR	Receptor
A6A12_RS04680	ENOG4105E93	esterase
A6A12_RS04695	ENOG410607W	Transposase
A6A12_RS04710	ENOG4105WQI	isochorismatase
A6A12_RS04715	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
A6A12_RS04720	ENOG4105E4F	Isochorismate synthase
A6A12_RS04725	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
A6A12_RS04730	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A6A12_RS04745	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A6A12_RS04750	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6A12_RS04760	ENOG4105CHW	UPF0052 protein
A6A12_RS04765	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A6A12_RS04770	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
A6A12_RS04775	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A6A12_RS04780	ENOG4105M00	molybdopterin converting factor, subunit 1
A6A12_RS04785	ENOG4108ZAF	Molybdopterin
A6A12_RS04790	ENOG4105BZU	Histidine kinase
A6A12_RS04805	ENOG4108I5U	Uridine phosphorylase
A6A12_RS04815	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A6A12_RS04820	ENOG4105D1F	ATP-binding protein
A6A12_RS04825	ENOG4105DBI	uridine monophosphokinase
A6A12_RS04830	ENOG4108GAE	asmA family
A6A12_RS04835	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
A6A12_RS04840	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
A6A12_RS04845	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
A6A12_RS04855	ENOG4108AEY	RNA polymerase sigma factor
A6A12_RS04870	ENOG4105CHU	acetyl-coa acetyltransferase
A6A12_RS04875	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A6A12_RS04880	ENOG41069NU	Nitroreductase
A6A12_RS04885	ENOG4105EJC	lysr family transcriptional regulator
A6A12_RS04890	ENOG4105I93	response regulator
A6A12_RS04900	ENOG4105WD1	Membrane
A6A12_RS04905	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A6A12_RS04910	ENOG4107QMP	dna polymerase iii subunits gamma and tau
A6A12_RS04915	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A6A12_RS04920	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A6A12_RS04925	ENOG4105KRS	Proteinase inhibitor
A6A12_RS04930	ENOG4108ZZ3	UPF0260 protein
A6A12_RS04945	ENOG4105DHI	Methyltransferase
A6A12_RS04950	ENOG4105DSB	aldose 1-epimerase
A6A12_RS04960	ENOG4105E0X	reductase
A6A12_RS04970	ENOG4105VUT	cytoplasmic protein
A6A12_RS04975	ENOG4105HDK	L-asparaginase
A6A12_RS04980	ENOG4105D07	Signal peptide peptidase, SppA
A6A12_RS04985	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A6A12_RS04990	ENOG4105CIY	formyltetrahydrofolate deformylase
A6A12_RS05000	ENOG4105DVT	helicase
A6A12_RS05005	ENOG41072GX	Peptidase M22 Glycoprotease
A6A12_RS05020	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
A6A12_RS05025	ENOG4105CEY	Amp-dependent synthetase and ligase
A6A12_RS05030	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
A6A12_RS05040	ENOG4107QMS	site-determining protein
A6A12_RS05045	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
A6A12_RS05055	ENOG4105CVE	Lytic murein transglycosylase
A6A12_RS05060	ENOG4105EJC	lysr family transcriptional regulator
A6A12_RS05065	ENOG4105D9N	nucleoside
A6A12_RS05075	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A6A12_RS05090	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
A6A12_RS05100	ENOG4105C3R	Methionine synthase
A6A12_RS05105	ENOG4105C94	Transporter
A6A12_RS05115	ENOG4105C1J	atp-dependent rna helicase
A6A12_RS05125	ENOG4105EJQ	L-serine dehydratase
A6A12_RS05130	ENOG4105CNG	UPF0061 protein
A6A12_RS05140	ENOG4105E0F	Histidine kinase
A6A12_RS05145	ENOG4108JP0	extracellular solute-binding protein family 1
A6A12_RS05155	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
A6A12_RS05160	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
A6A12_RS05165	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
A6A12_RS05170	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6A12_RS05175	ENOG4105CQZ	Histidine kinase
A6A12_RS05185	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A6A12_RS05190	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A6A12_RS05200	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A6A12_RS05205	ENOG4105K70	DNA-binding protein
A6A12_RS05210	ENOG4105EIN	peptidylprolyl cis-trans isomerase
A6A12_RS05215	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
A6A12_RS05220	ENOG4105CAT	Cytidine monophosphate kinase
A6A12_RS05225	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A6A12_RS05230	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A6A12_RS05235	ENOG4105Q4A	inner membrane protein yciS
A6A12_RS05240	ENOG4105CFV	Tetratricopeptide repeat protein
A6A12_RS05245	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A6A12_RS05255	ENOG4107R11	Transcriptional regulator
A6A12_RS05265	ENOG4105DCF	alanine dehydrogenase
A6A12_RS05275	ENOG4105CNU	cell division protein FtsK
A6A12_RS05285	ENOG4105D0M	Protease HtpX homolog
A6A12_RS05295	ENOG4105E1F	short-chain dehydrogenase reductase
A6A12_RS05310	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A6A12_RS05320	ENOG4105RHG	
A6A12_RS05330	ENOG4105CCT	upf0313 protein
A6A12_RS05340	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
A6A12_RS05355	ENOG4105DZ2	Transcriptional regulator
A6A12_RS05360	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
A6A12_RS05370	ENOG4105K9H	YciI-like protein
A6A12_RS05375	ENOG4105NAU	thioesterase Superfamily protein
A6A12_RS05380	ENOG4107835	probably involved in intracellular septation (By similarity)
A6A12_RS05390	ENOG4105CK2	sodium dicarboxylate symporter
A6A12_RS05400	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
A6A12_RS05405	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A6A12_RS05410	ENOG4105DK0	Indole-3-glycerol phosphate synthase
A6A12_RS05415	ENOG4108I0Q	anthranilate phosphoribosyltransferase
A6A12_RS05420	ENOG4105DDQ	anthranilate synthase
A6A12_RS05425	ENOG4105CRQ	synthase (Component I)
A6A12_RS05435	ENOG4105DB7	PHP domain protein
A6A12_RS05440	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
A6A12_RS05445	ENOG4105FE9	pseudouridine synthase
A6A12_RS05450	ENOG4105BZU	Histidine kinase
A6A12_RS05460	ENOG4105DU6	RNA polymerase
A6A12_RS05475	ENOG4108JJ8	(ABC) transporter
A6A12_RS05480	ENOG4108JJ9	ABC, transporter
A6A12_RS05485	ENOG4105C3M	thioredoxin reductase
A6A12_RS05500	ENOG4105C9B	Cysteine desulfurase
A6A12_RS05505	ENOG4107GZ4	SanA protein
A6A12_RS05515	ENOG4107R1I	NAD-dependent malic enzyme
A6A12_RS05530	ENOG4105D0C	transport protein
A6A12_RS05535	ENOG41090BQ	Glutaredoxin
A6A12_RS05545	ENOG4106KNT	transcriptional regulator
A6A12_RS05550	ENOG4105DY8	decarboxylase
A6A12_RS05560	ENOG4105DWU	Membrane
A6A12_RS05585	ENOG4105BZU	Histidine kinase
A6A12_RS05595	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
A6A12_RS05600	ENOG4107QTF	adenylosuccinate lyase
A6A12_RS05605	ENOG41075W9	High frequency lysogenization protein HflD homolog
A6A12_RS05610	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A6A12_RS05620	ENOG4107RE1	Inosine-guanosine kinase
A6A12_RS05625	ENOG4108SAU	DNA-binding protein H-ns
A6A12_RS05630	ENOG4107S6Z	Na H antiporter
A6A12_RS05640	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
A6A12_RS05645	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A6A12_RS05650	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
A6A12_RS05665	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A6A12_RS05670	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A6A12_RS05675	ENOG4108R99	pseudouridine synthase
A6A12_RS05685	ENOG4105VEQ	Cold shock protein
A6A12_RS05690	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
A6A12_RS05695	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A6A12_RS05700	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A6A12_RS05705	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
A6A12_RS05710	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
A6A12_RS05720	ENOG4105RKX	Protein of unknown function (DUF2498)
A6A12_RS05725	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A6A12_RS05730	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A6A12_RS05735	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A6A12_RS05755	ENOG4105HP8	regulator of competence-specific genes
A6A12_RS05760	ENOG4105ETE	Transcriptional regulator (LacI family
A6A12_RS05765	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
A6A12_RS05770	ENOG4106WF9	DNA-binding transcriptional regulator TorR
A6A12_RS05775	ENOG4107S90	membrAne
A6A12_RS05780	ENOG4106371	Methyltransferase
A6A12_RS05785	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
A6A12_RS05790	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
A6A12_RS05795	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
A6A12_RS05810	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A6A12_RS05815	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
A6A12_RS05820	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
A6A12_RS05825	ENOG4108N4M	Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns 3-P and prevents the transition of PtdIns 3-P to PtdIns 3,5-P2. It is one of the known effectors injected by Salmonella into the host cell and is required for invasion and for an efficient generation and maintenance of Salmonella-containing vacuole (SVC). Alteration of the phosphoinositide composition of the plasma membrane causes membrane ruffling and actin cytoskeleton rearrangements. The persistence of PtdIns 3-P diverts the SCV from the endocytic pathway resulting in enlarged vesicles, which are essential to create a favorable environment where Salmonella can replicate and avoid immune defenses of the host cell
A6A12_RS05830	ENOG41081XQ	Conserved Protein
A6A12_RS05835	ENOG4105C9M	aspartyl-trna synthetase
A6A12_RS05840	ENOG4107104	thymidine kinase
A6A12_RS05845	ENOG4105GFG	DUF218 domain
A6A12_RS05870	ENOG4105TMB	Formate nitrite transporter
A6A12_RS05885	ENOG4108J2R	molybdopterin oxidoreductase
A6A12_RS05895	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
A6A12_RS05910	ENOG4108JQ2	peptide transport system atp-binding protein
A6A12_RS05915	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
A6A12_RS05920	ENOG4108EU3	peptide transport system, permease
A6A12_RS05925	ENOG4108EKA	peptide transport system, permease
A6A12_RS05930	ENOG4108J59	Extracellular solute-binding protein, family 5
A6A12_RS05935	ENOG4105E51	psp operon transcriptional activator
A6A12_RS05940	ENOG41087YS	Phage shock protein A
A6A12_RS05945	ENOG4105YYT	phage shock protein B
A6A12_RS05955	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A6A12_RS05960	ENOG4105C28	cystathionine
A6A12_RS05970	ENOG4105C8J	)-transporter
A6A12_RS05975	ENOG4108W1A	pseudouridine synthase
A6A12_RS05990	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
A6A12_RS05995	ENOG4108VGW	abc transporter atp-binding protein
A6A12_RS06000	ENOG4105CXZ	ABC transporter, permease
A6A12_RS06005	ENOG4105VNH	ABC transporter solute-binding protein
A6A12_RS06015	ENOG4105XZD	Fe-S protein
A6A12_RS06045	ENOG4105C1J	atp-dependent rna helicase
A6A12_RS06060	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
A6A12_RS06065	ENOG4105EB3	Histidine kinase
A6A12_RS06080	ENOG4105CFI	type iii restriction protein res subunit
A6A12_RS06085	ENOG4105I08	Pseudouridine synthase
A6A12_RS06090	ENOG4105C2C	drug resistance transporter, Bcr CflA
A6A12_RS06100	ENOG4105CGD	Nad-dependent epimerase dehydratase
A6A12_RS06105	ENOG4105UQX	Mate efflux family protein
A6A12_RS06110	ENOG4108I0Y	(ABC) transporter
A6A12_RS06125	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A6A12_RS06145	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
A6A12_RS06150	ENOG4105C8Q	Methyl-accepting chemotaxis
A6A12_RS06180	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A6A12_RS06185	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A6A12_RS06190	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
A6A12_RS06195	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6A12_RS06200	ENOG4108N3W	hemolysin secretion protein
A6A12_RS06220	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
A6A12_RS06235	ENOG4107QSA	Oxaloacetate decarboxylase
A6A12_RS06240	ENOG4105D9Q	decarboxylase (Beta subunit)
A6A12_RS06245	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
A6A12_RS06250	ENOG4106YYS	transcriptional regulatory protein
A6A12_RS06260	ENOG4105CI0	Citrate lyase
A6A12_RS06265	ENOG4105CHY	citrate lyase, alpha
A6A12_RS06275	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
A6A12_RS06295	ENOG4105EIP	mannose-6-phosphate isomerase
A6A12_RS06300	ENOG4105DM4	PTS System
A6A12_RS06305	ENOG4108CIP	transcriptional regulator
A6A12_RS06315	ENOG4108YRF	PTS System
A6A12_RS06325	ENOG4105VYW	UPF0251 protein
A6A12_RS06350	ENOG4107SDZ	Galactoside transport system permease protein mglC
A6A12_RS06360	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A6A12_RS06365	ENOG41080IJ	Diacylglycerol kinase
A6A12_RS06370	ENOG4105GR3	Histidine kinase
A6A12_RS06375	ENOG4107EXC	regulatoR
A6A12_RS06405	ENOG4105CR4	methylisocitrate lyase
A6A12_RS06410	ENOG4105BZN	citrate synthase
A6A12_RS06415	ENOG4108I0Z	Aconitate hydratase
A6A12_RS06420	ENOG4105C7F	AcnD-accessory protein PrpF
A6A12_RS06425	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A6A12_RS06440	ENOG410667J	hydrolase
A6A12_RS06445	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A6A12_RS06450	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A6A12_RS06480	ENOG410607W	Transposase
A6A12_RS06490	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
A6A12_RS06495	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
A6A12_RS06500	ENOG4108MN8	Membrane
A6A12_RS06505	ENOG4105CDA	abc transporter atp-binding protein
A6A12_RS06510	ENOG4105DRP	amino acid AbC transporter
A6A12_RS06515	ENOG4105EZ7	amino acid ABC transporter
A6A12_RS06520	ENOG4107QXX	ABC transporter
A6A12_RS06525	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A6A12_RS06535	ENOG4108VPT	UPF0234 protein
A6A12_RS06540	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A6A12_RS06560	ENOG4105QNR	S1 RNA binding domain protein
A6A12_RS06570	ENOG4105DY2	Paraquat-inducible protein b
A6A12_RS06575	ENOG4105H2K	paraquat-inducible protein a
A6A12_RS06580	ENOG4105BZ1	(ABC) transporter
A6A12_RS06585	ENOG4108ZGC	gaf domain protein
A6A12_RS06590	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
A6A12_RS06595	ENOG4105CN1	protease
A6A12_RS06605	ENOG4105CD8	aminopeptidase N
A6A12_RS06615	ENOG4105C7I	Dehydrogenase
A6A12_RS06620	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
A6A12_RS06625	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
A6A12_RS06630	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A6A12_RS06640	ENOG4105C5H	ABC transporter
A6A12_RS06655	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
A6A12_RS06660	ENOG4105DAN	ATP-dependent protease
A6A12_RS06665	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
A6A12_RS06695	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
A6A12_RS06710	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
A6A12_RS06720	ENOG4105C59	p-type ATPase
A6A12_RS06735	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
A6A12_RS06740	ENOG4105Q9Y	Universal stress protein
A6A12_RS06745	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A6A12_RS06765	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A6A12_RS06770	ENOG4105F38	ABC transporter, permease
A6A12_RS06775	ENOG4105D38	putrescine abc transporter
A6A12_RS06780	ENOG4107RUE	extracellular solute-binding protein family 1
A6A12_RS06785	ENOG4108HM4	ABC transporter
A6A12_RS06790	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A6A12_RS06800	ENOG4105C5H	ABC transporter
A6A12_RS06805	ENOG4108KX4	response regulator
A6A12_RS06810	ENOG4105BZU	Histidine kinase
A6A12_RS06815	ENOG4105CXY	transporter
A6A12_RS06820	ENOG4105C4Y	ABC transporter
A6A12_RS06825	ENOG4107RCV	ABC transporter, permease
A6A12_RS06830	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A6A12_RS06835	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A6A12_RS06840	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
A6A12_RS06855	ENOG4106IUH	DTW domain containing protein
A6A12_RS06865	ENOG4108N3W	hemolysin secretion protein
A6A12_RS06870	ENOG4107TT5	NLP P60 protein
A6A12_RS06890	ENOG4107QI1	Mate efflux family protein
A6A12_RS06900	ENOG4108NRW	Phospholipase, patatin family
A6A12_RS06915	ENOG4109015	Biopolymer transport protein exbD tolR
A6A12_RS06955	ENOG4108RXX	maleylacetoacetate isomerase
A6A12_RS06965	ENOG4105F1J	Homogentisate 1,2-dioxygenase
A6A12_RS06970	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
A6A12_RS06975	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
A6A12_RS06990	ENOG4105BZG	amino acid carrier protein
A6A12_RS06995	ENOG410829K	Lysine exporter protein (Lyse ygga)
A6A12_RS07000	ENOG4105CTD	carboxy-peptidase
A6A12_RS07030	ENOG4107UNZ	domain protein
A6A12_RS07055	ENOG4107RRE	RNA-directed DNA polymerase
A6A12_RS07070	ENOG4105CTD	carboxy-peptidase
A6A12_RS07075	ENOG4105CIB	oxidoreductase Domain protein
A6A12_RS07085	ENOG4105C26	Dehydrogenase
A6A12_RS07100	ENOG4105EDK	PfkB domain protein
A6A12_RS07105	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
A6A12_RS07110	ENOG4105DH8	myo-inositol catabolism
A6A12_RS07120	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
A6A12_RS07125	ENOG4105C2X	Arabinose 5-phosphate isomerase
A6A12_RS07130	ENOG4107RUZ	Sss sodium solute transporter superfamily
A6A12_RS07155	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A6A12_RS07160	ENOG4108R4R	Iron-regulated virulence regulatory protein
A6A12_RS07170	ENOG4105CQ7	ATP-dependent helicase
A6A12_RS07205	ENOG4105CFG	Acts as a chaperone (By similarity)
A6A12_RS07240	ENOG4105DDV	Transcriptional regulator (LacI family
A6A12_RS07245	ENOG4105CS2	ec 3.2.1.21
A6A12_RS07250	ENOG4105C1J	atp-dependent rna helicase
A6A12_RS07255	ENOG4107QY8	reductase
A6A12_RS07260	ENOG4105CUW	cytochrome C-TYPE protein
A6A12_RS07265	ENOG4105VEQ	Cold shock protein
A6A12_RS07275	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6A12_RS07280	ENOG4105BZU	Histidine kinase
A6A12_RS07285	ENOG4105C8P	)-transporter
A6A12_RS07290	ENOG4108NVR	Methyl-accepting chemotaxis
A6A12_RS07295	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A6A12_RS07305	ENOG4105BZU	Histidine kinase
A6A12_RS07315	ENOG4105D9U	N-acetyltransferase
A6A12_RS07320	ENOG4108JU8	Transcriptional regulator
A6A12_RS07325	ENOG4106K28	UPF0283 membrane protein
A6A12_RS07330	ENOG4105CM6	amino acid regulated cytosolic protein
A6A12_RS07345	ENOG4105CRQ	synthase (Component I)
A6A12_RS07350	ENOG4105P8F	nudix hydrolase
A6A12_RS07355	ENOG4105C44	Serine transporter
A6A12_RS07360	ENOG4105EJQ	L-serine dehydratase
A6A12_RS07370	ENOG4108K8S	endonuclease I
A6A12_RS07375	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
A6A12_RS07380	ENOG4105C8Q	Methyl-accepting chemotaxis
A6A12_RS07385	ENOG4105C5S	asparaginyl-tRNA synthetase
A6A12_RS07395	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A6A12_RS07400	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
A6A12_RS07405	ENOG4105BZU	Histidine kinase
A6A12_RS07410	ENOG4108V3W	Chemotaxis protein, CheW
A6A12_RS07420	ENOG4105CBS	Chea signal transduction histidine kinase
A6A12_RS07430	ENOG4108VYJ	response regulator receiver protein
A6A12_RS07435	ENOG4105C8Q	Methyl-accepting chemotaxis
A6A12_RS07440	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A6A12_RS07445	ENOG4105CGF	Aromatic amino acid aminotransferase
A6A12_RS07450	ENOG41080XQ	Signal transduction protein with cbs domains
A6A12_RS07460	ENOG4105C8Q	Methyl-accepting chemotaxis
A6A12_RS07465	ENOG4105C94	Transporter
A6A12_RS07470	ENOG41067TZ	transcriptional regulator, MarR family
A6A12_RS07485	ENOG4105C5X	domain protein
A6A12_RS07490	ENOG4105EAQ	(twin-arginine translocation) pathway signal
A6A12_RS07495	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
A6A12_RS07520	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
A6A12_RS07525	ENOG4105DKQ	ROK family
A6A12_RS07535	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
A6A12_RS07540	ENOG41090JE	Utilization Protein
A6A12_RS07545	ENOG4105WQ5	TonB family
A6A12_RS07550	ENOG41090AP	transport protein
A6A12_RS07555	ENOG4106GFD	transport protein
A6A12_RS07565	ENOG4105EHG	Permease protein
A6A12_RS07570	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A6A12_RS07575	ENOG4105C72	UPF0176 protein
A6A12_RS07585	ENOG4105C8Q	Methyl-accepting chemotaxis
A6A12_RS07590	ENOG4107R3K	hydrolase
A6A12_RS07600	ENOG4105C5Y	PTS System
A6A12_RS07605	ENOG4105D7K	pfkb domain protein
A6A12_RS07610	ENOG4105BZU	Histidine kinase
A6A12_RS07620	ENOG4105C8Q	Methyl-accepting chemotaxis
A6A12_RS07645	ENOG4105E18	UPF0276 protein
A6A12_RS07660	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A6A12_RS07665	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A6A12_RS07675	ENOG4105M4H	endoribonuclease L-psp
A6A12_RS07715	ENOG4108YAB	Invasion protein
A6A12_RS07770	ENOG4108UW8	fha domain-containing protein
A6A12_RS07795	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A6A12_RS07865	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A6A12_RS07905	ENOG4107R88	Chemotaxis protein (CheV)
A6A12_RS07915	ENOG4106YYS	transcriptional regulatory protein
A6A12_RS07920	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
A6A12_RS07935	ENOG4107V40	secretion protein, HlyD family
A6A12_RS07955	ENOG4105CVG	Homoserine O-transsuccinylase
A6A12_RS07960	ENOG41090FY	type IV pilus biogenesis stability protein PilW
A6A12_RS07975	ENOG4108VKG	metal-dependent hydrolase
A6A12_RS07985	ENOG4107RSM	transcriptional regulator
A6A12_RS08005	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
A6A12_RS08010	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
A6A12_RS08025	ENOG4108YZT	Adenosylcobinamide kinase
A6A12_RS08030	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
A6A12_RS08035	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
A6A12_RS08040	ENOG4105EUK	rtx toxin RtxA
A6A12_RS08045	ENOG4108RC6	RTX toxin
A6A12_RS08055	ENOG4108JJA	ABC, transporter
A6A12_RS08070	ENOG4105C8Q	Methyl-accepting chemotaxis
A6A12_RS08075	ENOG4105K4T	epimerase
A6A12_RS08080	ENOG4108ETY	sodium dicarboxylate symporter
A6A12_RS08085	ENOG4105CJB	Exodeoxyribonuclease I
A6A12_RS08090	ENOG4105VAW	lrga family
A6A12_RS08095	ENOG41067MG	lrgb family
A6A12_RS08115	ENOG4107SDU	Methyl-accepting chemotaxis
A6A12_RS08120	ENOG4105FQ6	thiopurine methyltransferase
A6A12_RS08130	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A6A12_RS08135	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A6A12_RS08180	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
A6A12_RS08185	ENOG4105WH1	Two component transcriptional regulator luxr family
A6A12_RS08190	ENOG4105CQ2	DNA polymerase
A6A12_RS08200	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A6A12_RS08215	ENOG4105CZE	histidine utilization repressor
A6A12_RS08225	ENOG41088SP	formiminoglutamate hydrolase
A6A12_RS08230	ENOG4105CGP	Urocanate hydratase
A6A12_RS08235	ENOG4105C84	Histidine ammonia-lyase
A6A12_RS08250	ENOG4105CQB	FAD linked oxidase domain protein
A6A12_RS08285	ENOG4107QPN	acyl-Coa dehydrogenase
A6A12_RS08290	ENOG41067SE	Tetr family transcriptional regulator
A6A12_RS08305	ENOG4105C26	Dehydrogenase
A6A12_RS08310	ENOG4105BZU	Histidine kinase
A6A12_RS08440	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A6A12_RS08455	ENOG4105CAR	Terminase, large subunit
A6A12_RS08520	ENOG4108MXB	Protein of unknown function (DUF968)
A6A12_RS08610	ENOG4106V8H	Nucleoid-associated protein
A6A12_RS08735	ENOG4105DFP	Integrase
A6A12_RS08745	ENOG4108RNS	Exports L-alanine (By similarity)
A6A12_RS08750	ENOG4105BZU	Histidine kinase
A6A12_RS08780	ENOG4105UFD	tol-pal system protein YbgF
A6A12_RS08785	ENOG4105KCK	Peptidoglycan-associated lipoprotein
A6A12_RS08790	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
A6A12_RS08800	ENOG4105M8F	Biopolymer transport protein exbD tolR
A6A12_RS08805	ENOG4105E02	MotA TolQ exbB proton channel
A6A12_RS08810	ENOG4107YD3	Thioesterase
A6A12_RS08815	ENOG4105KJB	cyd operon protein YbgE
A6A12_RS08825	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A6A12_RS08830	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A6A12_RS08835	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A6A12_RS08840	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A6A12_RS08845	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
A6A12_RS08855	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A6A12_RS08860	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
A6A12_RS08865	ENOG4105D58	Diguanylate phosphodiesterase
A6A12_RS08870	ENOG4105K5B	UPF0225 protein
A6A12_RS08880	ENOG4105DVT	helicase
A6A12_RS08890	ENOG4108URS	primosomal replication protein n''
A6A12_RS08895	ENOG4106428	Protein of unknown function (DUF2496)
A6A12_RS08900	ENOG4105C8Q	Methyl-accepting chemotaxis
A6A12_RS08905	ENOG4105CGK	Exodeoxyribonuclease III
A6A12_RS08910	ENOG4106YG3	ABC transporter
A6A12_RS08915	ENOG4105DSP	amino acid AbC transporter
A6A12_RS08920	ENOG4105E89	ABC transporter
A6A12_RS08925	ENOG4108JEH	abc transporter atp-binding protein
A6A12_RS08940	ENOG4105C6N	Formate acetyltransferase
A6A12_RS08950	ENOG4108NVR	Methyl-accepting chemotaxis
A6A12_RS08955	ENOG4105F1A	Pyruvate formate-lyase
A6A12_RS08965	ENOG4105XWI	UPF0304 protein
A6A12_RS08970	ENOG4105CYN	Serine protein kinase
A6A12_RS08975	ENOG4106AKX	UPF0229 protein
A6A12_RS08980	ENOG4105ED1	spovr family
A6A12_RS08990	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
A6A12_RS08995	ENOG4105W49	UPF0434 protein
A6A12_RS09000	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
A6A12_RS09005	ENOG4105BZ1	(ABC) transporter
A6A12_RS09010	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
A6A12_RS09020	ENOG4105D60	lipoprotein releasing system transmembrane protein
A6A12_RS09025	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A6A12_RS09030	ENOG4105D60	lipoprotein releasing system transmembrane protein
A6A12_RS09040	ENOG4108JA2	transcriptioN-repair coupling factor
A6A12_RS09050	ENOG4106M3D	hemolysin
A6A12_RS09055	ENOG4105CEP	NADH dehydrogenase
A6A12_RS09060	ENOG4105D0Y	UPF0227 protein
A6A12_RS09085	ENOG4105K59	histidine triad (HIT) protein
A6A12_RS09090	ENOG4108NVR	Methyl-accepting chemotaxis
A6A12_RS09100	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
A6A12_RS09110	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
A6A12_RS09115	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A6A12_RS09120	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
A6A12_RS09125	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A6A12_RS09135	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A6A12_RS09140	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A6A12_RS09145	ENOG4105D1H	recombination factor protein RarA
A6A12_RS09150	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
A6A12_RS09155	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A6A12_RS09160	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
A6A12_RS09165	ENOG4108JJB	ABC transporter
A6A12_RS09170	ENOG4105C7J	ABC transporter, permease
A6A12_RS09180	ENOG4105PQ6	UPF0208 membrane protein
A6A12_RS09185	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
A6A12_RS09190	ENOG4108DNC	Involved in acetate metabolism (By similarity)
A6A12_RS09195	ENOG4105CHF	Glutathione S-transferase
A6A12_RS09200	ENOG4108JQ7	(ABC) transporter
A6A12_RS09205	ENOG4105C3U	ABC transporter
A6A12_RS09210	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A6A12_RS09215	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A6A12_RS09220	ENOG4107QSI	ABC, transporter
A6A12_RS09225	ENOG4105BZU	Histidine kinase
A6A12_RS09230	ENOG4105BZU	Histidine kinase
A6A12_RS09265	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A6A12_RS09290	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A6A12_RS09295	ENOG4105C84	Histidine ammonia-lyase
A6A12_RS09320	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A6A12_RS09325	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
A6A12_RS09330	ENOG4105C2D	reductase
A6A12_RS09335	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A6A12_RS09340	ENOG4105RW8	MltA-interacting MipA family protein
A6A12_RS09355	ENOG4108UHU	Aldolase
A6A12_RS09360	ENOG4105C6Z	Gluconate
A6A12_RS09365	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
A6A12_RS09370	ENOG4105C01	Dihydroxy-acid dehydratase
A6A12_RS09375	ENOG4105DIQ	Transcriptional regulator
A6A12_RS09390	ENOG41062D9	Histidine kinase
A6A12_RS09400	ENOG4105D0C	transport protein
A6A12_RS09410	ENOG4105EW9	transcriptional regulator AsnC family
A6A12_RS09415	ENOG4105DIJ	Phosphoethanolamine transferase
A6A12_RS09420	ENOG4105DHQ	Histidine kinase
A6A12_RS09435	ENOG4105EMU	Dehydrogenase
A6A12_RS09445	ENOG4108IQE	Amp-dependent synthetase and ligase
A6A12_RS09470	ENOG4106TD9	Diguanylate cyclase
A6A12_RS09485	ENOG4108MNP	Glycoprotein polysaccharide metabolism
A6A12_RS09490	ENOG4105C29	acyl-CoA thioesterase
A6A12_RS09495	ENOG4108XM1	transcriptional regulator AsnC family
A6A12_RS09515	ENOG4107S74	Lysophospholipid transporter LplT
A6A12_RS09535	ENOG4105CEY	Amp-dependent synthetase and ligase
A6A12_RS09545	ENOG4108IPT	Naphthoate synthase
A6A12_RS09555	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
A6A12_RS09560	ENOG4105E4F	Isochorismate synthase
A6A12_RS09570	ENOG4105CHM	Aminotransferase
A6A12_RS09575	ENOG4105DK2	UPF0207 protein
A6A12_RS09580	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
A6A12_RS09595	ENOG4105ERU	peptidase
A6A12_RS09600	ENOG4105UBK	short-chain dehydrogenase reductase
A6A12_RS09610	ENOG4105DAG	ROK family
A6A12_RS09615	ENOG4105CA9	Pyruvate kinase
A6A12_RS09620	ENOG4108NRW	Phospholipase, patatin family
A6A12_RS09635	ENOG4105C8J	)-transporter
A6A12_RS09645	ENOG4105CI1	PTS System
A6A12_RS09650	ENOG4105F8V	Hydrolase, tatD family
A6A12_RS09655	ENOG4107QRG	dna polymerase iii
A6A12_RS09660	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A6A12_RS09665	ENOG4105HHA	aminodeoxychorismate lyase
A6A12_RS09670	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
A6A12_RS09675	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A6A12_RS09680	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A6A12_RS09685	ENOG4105CHR	reductase
A6A12_RS09690	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A6A12_RS09700	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
A6A12_RS09710	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
A6A12_RS09715	ENOG4108UHJ	MAF-like protein
A6A12_RS09720	ENOG4105EI2	Pseudouridine synthase
A6A12_RS09725	ENOG4105C03	ribonuclease
A6A12_RS09735	ENOG4105C0A	alcohol dehydrogenase
A6A12_RS09740	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A6A12_RS09745	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A6A12_RS09750	ENOG4105DFD	Na H antiporter
A6A12_RS09760	ENOG4106V8H	Nucleoid-associated protein
A6A12_RS09765	ENOG4105YDX	UPF0352 protein
A6A12_RS09770	ENOG4105E68	Sulfatase
A6A12_RS09780	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
A6A12_RS09785	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
A6A12_RS09800	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A6A12_RS09805	ENOG4105M2J	Glutaredoxin
A6A12_RS09810	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A6A12_RS09825	ENOG410903C	(LipO)protein
A6A12_RS09835	ENOG4108M1T	Cytochrome c-type biogenesis protein
A6A12_RS09840	ENOG4107QX9	Thiol disulfide interChange protein
A6A12_RS09845	ENOG4105DA4	cytochrome c-type biogenesis protein
A6A12_RS09850	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
A6A12_RS09860	ENOG41060IM	Heme exporter protein
A6A12_RS09865	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
A6A12_RS09880	ENOG4108V3W	Chemotaxis protein, CheW
A6A12_RS09890	ENOG4107QJE	Chromosome Partitioning Protein
A6A12_RS09895	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A6A12_RS09905	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
A6A12_RS09910	ENOG4108VYJ	response regulator receiver protein
A6A12_RS09915	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6A12_RS09925	ENOG4105FZW	flagellar biosynthesis regulator FlhF
A6A12_RS09930	ENOG4105D7B	Flagellar biosynthesis protein flha
A6A12_RS09935	ENOG4108BY2	phosphohistidine phosphatase
A6A12_RS09940	ENOG4108JQM	Insulinase (Peptidase family M16)
A6A12_RS09945	ENOG4106ZCM	YecM protein
A6A12_RS09950	ENOG4105C75	arginyL-tRNA synthetase
A6A12_RS09970	ENOG4105XFK	Ferrous iron transport protein A
A6A12_RS09975	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
A6A12_RS09980	ENOG4105NXV	High-affinity zinc uptake system protein
A6A12_RS09985	ENOG4105FDK	ABC transporter
A6A12_RS09990	ENOG4105FAV	ABC, transporter
A6A12_RS09995	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
A6A12_RS10000	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
A6A12_RS10005	ENOG4105C7S	Dehydrogenase
A6A12_RS10010	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
A6A12_RS10015	ENOG4105E33	succinate dehydrogenase
A6A12_RS10020	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
A6A12_RS10025	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
A6A12_RS10030	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
A6A12_RS10035	ENOG4105BZN	citrate synthase
A6A12_RS10040	ENOG4107QNR	UPF0135 protein
A6A12_RS10050	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
A6A12_RS10055	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
A6A12_RS10060	ENOG4105EV9	Alpha Beta Hydrolase
A6A12_RS10070	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
A6A12_RS10075	ENOG41067MG	lrgb family
A6A12_RS10080	ENOG4105VAW	lrga family
A6A12_RS10085	ENOG4105CMU	LysR family (Transcriptional regulator
A6A12_RS10095	ENOG41090R7	Ferric uptake
A6A12_RS10100	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A6A12_RS10105	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
A6A12_RS10110	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A6A12_RS10115	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
A6A12_RS10120	ENOG4105Q8W	reductase
A6A12_RS10125	ENOG4105MH2	YfcL protein
A6A12_RS10130	ENOG4108BPE	-transporting atpase
A6A12_RS10135	ENOG4105EN6	Membrane
A6A12_RS10145	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
A6A12_RS10150	ENOG4108DG9	Smr protein MutS2
A6A12_RS10155	ENOG4105D00	flagellar biosynthetic protein flhB
A6A12_RS10160	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
A6A12_RS10165	ENOG4105VS8	Flagellar biosynthetic protein fliq
A6A12_RS10170	ENOG4105CN7	Flagellar biosynthetic protein FliP
A6A12_RS10175	ENOG4105VTB	flagellar biosynthesis protein fliO
A6A12_RS10180	ENOG4105DD5	Flagellar motor switch protein
A6A12_RS10185	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A6A12_RS10205	ENOG4108JIR	Flagellum-specific ATP synthase
A6A12_RS10215	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A6A12_RS10220	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
A6A12_RS10225	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
A6A12_RS10235	ENOG4105BZU	Histidine kinase
A6A12_RS10245	ENOG4105MQ3	flagellar protein FliS
A6A12_RS10255	ENOG4107BRV	flagellar capping protein
A6A12_RS10260	ENOG41063QE	flagellar protein FlaG
A6A12_RS10265	ENOG4105I03	Flagellin
A6A12_RS10270	ENOG4105I03	Flagellin
A6A12_RS10275	ENOG4105I03	Flagellin
A6A12_RS10280	ENOG4105EZR	dyp-type peroxidase family protein
A6A12_RS10285	ENOG4105QZU	Inner membrane protein YfeZ
A6A12_RS10305	ENOG4105KUZ	arsenate reductase
A6A12_RS10325	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A6A12_RS10365	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A6A12_RS10410	ENOG4105C4R	Atp-dependent dna helicase
A6A12_RS10440	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A6A12_RS10445	ENOG4105C8Q	Methyl-accepting chemotaxis
A6A12_RS10460	ENOG4105ERG	peptidase m48, ste24p
A6A12_RS10465	ENOG4105K89	arsenate reductase
A6A12_RS10470	ENOG4105CS1	NAD(P)H quinone oxidoreductase
A6A12_RS10485	ENOG4105C2W	permease
A6A12_RS10490	ENOG4108Z66	YbaK ebsC protein
A6A12_RS10495	ENOG4105CGH	5'-nucleotidase
A6A12_RS10500	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
A6A12_RS10505	ENOG41063JG	Transcriptional regulator
A6A12_RS10510	ENOG4108YY7	Invasion gene expression up-regulator SirB
A6A12_RS10515	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A6A12_RS10520	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
A6A12_RS10525	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
A6A12_RS10535	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
A6A12_RS10545	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
A6A12_RS10550	ENOG4105C3G	gtp-binding protein
A6A12_RS10585	ENOG4105I03	Flagellin
A6A12_RS10590	ENOG4105I03	Flagellin
A6A12_RS10600	ENOG4105DTJ	flagellar hook-associated protein
A6A12_RS10610	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
A6A12_RS10615	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
A6A12_RS10620	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
A6A12_RS10625	ENOG4105CGA	flagellar basal-body rod protein FlgG
A6A12_RS10630	ENOG4108KPB	Flagellar basal-body rod protein FlgF
A6A12_RS10635	ENOG4105BZE	flagellar hook protein, FlgE
A6A12_RS10640	ENOG4105W00	Flagellar hook capping protein
A6A12_RS10645	ENOG4108ZC9	flagellar basal-body rod protein flgc
A6A12_RS10650	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
A6A12_RS10655	ENOG4105BZU	Histidine kinase
A6A12_RS10660	ENOG4107R88	Chemotaxis protein (CheV)
A6A12_RS10705	ENOG4105UYK	outer membrane protein a
A6A12_RS10710	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A6A12_RS10715	ENOG4105C59	p-type ATPase
A6A12_RS10725	ENOG4105E2D	ec 3.2.1.52
A6A12_RS10740	ENOG4105FE9	pseudouridine synthase
A6A12_RS10745	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A6A12_RS10750	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A6A12_RS10755	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A6A12_RS10760	ENOG4105E7A	Glutamine amidotransferase
A6A12_RS10765	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
A6A12_RS10770	ENOG4107QPN	acyl-Coa dehydrogenase
A6A12_RS10780	ENOG4107RZZ	dna polymerase iii epsilon subunit
A6A12_RS10790	ENOG4105D1A	Methyltransferase
A6A12_RS10795	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A6A12_RS10800	ENOG4105E9H	Lytic Murein transglycosylase
A6A12_RS10810	ENOG4107NA1	Endonuclease Exonuclease phosphatase
A6A12_RS10815	ENOG4108YZA	Nitrogen regulatory protein pii
A6A12_RS10820	ENOG4105N7H	Cytochrome
A6A12_RS10825	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A6A12_RS10830	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
A6A12_RS10835	ENOG4105C0B	DNA polymerase III (alpha subunit)
A6A12_RS10840	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A6A12_RS10845	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A6A12_RS10850	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A6A12_RS10855	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
A6A12_RS10860	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A6A12_RS10865	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
A6A12_RS10875	ENOG4105DZP	Membrane-associated zinc metalloprotease
A6A12_RS10880	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
A6A12_RS10885	ENOG4105KNE	Phosphatidate cytidylyltransferase
A6A12_RS10890	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A6A12_RS10895	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
A6A12_RS10900	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A6A12_RS10905	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
A6A12_RS10910	ENOG4105CE9	30S ribosomal protein S2
A6A12_RS10915	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A6A12_RS10920	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
A6A12_RS10925	ENOG4108T8E	UPF0325 protein
A6A12_RS10930	ENOG4108ZAI	phosphatidylglycerophosphatase a
A6A12_RS10935	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A6A12_RS10940	ENOG4107YIM	Involved in the transcription termination process (By similarity)
A6A12_RS10945	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
A6A12_RS10960	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A6A12_RS10970	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
A6A12_RS10980	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
A6A12_RS10985	ENOG4108DJV	Fermentation respiration switch protein
A6A12_RS10990	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
A6A12_RS10995	ENOG4105C7N	Xanthine uracil vitamin C permease
A6A12_RS11000	ENOG4105CIN	aminoacyl-histidine dipeptidase
A6A12_RS11005	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A6A12_RS11010	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A6A12_RS11020	ENOG4105C8J	)-transporter
A6A12_RS11035	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A6A12_RS11045	ENOG4105CJ2	(LipO)protein
A6A12_RS11050	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
A6A12_RS11055	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A6A12_RS11060	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A6A12_RS11065	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A6A12_RS11070	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A6A12_RS11075	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A6A12_RS11080	ENOG4105M85	Bola protein
A6A12_RS11085	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
A6A12_RS11095	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A6A12_RS11100	ENOG4105EYM	Major Facilitator superfamily
A6A12_RS11110	ENOG4105K6V	RNA polymerase
A6A12_RS11125	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A6A12_RS11130	ENOG4107S0N	DJ-1 family
A6A12_RS11135	ENOG4105C9B	Cysteine desulfurase
A6A12_RS11140	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
A6A12_RS11145	ENOG4105CUZ	uba thif-type nad fad binding protein
A6A12_RS11150	ENOG4105CA3	membrane-bound lytic murein transglycosylase
A6A12_RS11160	ENOG4107QZM	n-acetylglutamate synthase
A6A12_RS11170	ENOG4107QYX	exodeoxyribonuclease v alpha
A6A12_RS11175	ENOG4107QKA	exodeoxyribonuclease V beta
A6A12_RS11180	ENOG4105DSY	exodeoxyribonuclease V, gamma
A6A12_RS11195	ENOG4105X2V	dna damage-inducible protein
A6A12_RS11200	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
A6A12_RS11210	ENOG4108R6G	acetyltransferase
A6A12_RS11230	ENOG41060NJ	transcriptional regulator
A6A12_RS11235	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A6A12_RS11240	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
A6A12_RS11245	ENOG4105CMR	udp-glucose 4-epimerase
A6A12_RS11260	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A6A12_RS11265	ENOG4108IQE	Amp-dependent synthetase and ligase
A6A12_RS11270	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
A6A12_RS11280	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
A6A12_RS11290	ENOG4105EAC	phosphoserine phosphatase
A6A12_RS11300	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
A6A12_RS11305	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
A6A12_RS11320	ENOG4105D9N	nucleoside
A6A12_RS11325	ENOG4105EYA	deoxyribonuclease
A6A12_RS11330	ENOG4105D1Q	UPF0246 protein
A6A12_RS11335	ENOG4105BZG	amino acid carrier protein
A6A12_RS11350	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
A6A12_RS11355	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
A6A12_RS11360	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
A6A12_RS11365	ENOG4105D98	threonine synthase
A6A12_RS11370	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
A6A12_RS11385	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
A6A12_RS11390	ENOG41065U4	response regulator
A6A12_RS11400	ENOG4105BZU	Histidine kinase
A6A12_RS11405	ENOG4105N5T	Radical SAM Protein
A6A12_RS11420	ENOG4105CBC	glutamate synthase
A6A12_RS11425	ENOG4105BZ8	glutamate synthase
A6A12_RS11440	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
A6A12_RS11450	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
A6A12_RS11455	ENOG4105EN6	Membrane
A6A12_RS11460	ENOG4105VP0	transcriptional regulator, lysR family
A6A12_RS11465	ENOG4105EJ9	Membrane
A6A12_RS11475	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A6A12_RS11480	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
A6A12_RS11485	ENOG4105M6F	mutator MutT protein
A6A12_RS11490	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A6A12_RS11500	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A6A12_RS11505	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A6A12_RS11510	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
A6A12_RS11515	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
A6A12_RS11520	ENOG4105DFU	Cell wall formation (By similarity)
A6A12_RS11525	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A6A12_RS11535	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A6A12_RS11545	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
A6A12_RS11550	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
A6A12_RS11555	ENOG4105CJN	penicillin-binding protein
A6A12_RS11560	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
A6A12_RS11575	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
A6A12_RS11580	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
A6A12_RS11590	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
A6A12_RS11595	ENOG4105W4M	Transport-associated protein
A6A12_RS11600	ENOG4105KB2	stringent starvation protein b
A6A12_RS11605	ENOG4107MKT	Stringent starvation protein a
A6A12_RS11610	ENOG4105EIX	cytochrome c1
A6A12_RS11615	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A6A12_RS11620	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A6A12_RS11625	ENOG4108UJD	30S ribosomal protein S9
A6A12_RS11640	ENOG4105D6Z	AFG1 family ATPase
A6A12_RS11645	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
A6A12_RS11650	ENOG4105C0H	protease
A6A12_RS11655	ENOG4105C0H	protease
A6A12_RS11660	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6A12_RS11665	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6A12_RS11670	ENOG4105IPS	esterase
A6A12_RS11675	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
A6A12_RS11680	ENOG4108SX3	cytoplasmic protein
A6A12_RS11685	ENOG41087AY	ADP-Ribose pyrophosphatase
A6A12_RS11690	ENOG4105DFG	type I secretion outer membrane protein
A6A12_RS11700	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
A6A12_RS11705	ENOG4108NVR	Methyl-accepting chemotaxis
A6A12_RS11715	ENOG4105I7R	Adenylate cyclase
A6A12_RS11720	ENOG4107IX6	phosphate transport regulator
A6A12_RS11725	ENOG4105CJ3	phosphate transporter
A6A12_RS11730	ENOG4106MWK	domain protein
A6A12_RS11745	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
A6A12_RS11750	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A6A12_RS11755	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A6A12_RS11760	ENOG4105DXN	mazG family
A6A12_RS11765	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A6A12_RS11770	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A6A12_RS11775	ENOG4105BZU	Histidine kinase
A6A12_RS11780	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
A6A12_RS11790	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
A6A12_RS11800	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
A6A12_RS11805	ENOG4105C3F	Signal peptidase i
A6A12_RS11810	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A6A12_RS11815	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
A6A12_RS11830	ENOG4105EMN	RNA polymerase sigma factor
A6A12_RS11835	ENOG4108IYU	L-aspartate oxidase
A6A12_RS11845	ENOG4105Y75	tpr repeat protein
A6A12_RS11865	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A6A12_RS11870	ENOG4105D0A	hydroxylase
A6A12_RS11880	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
A6A12_RS11890	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
A6A12_RS11895	ENOG4105E66	phosphoriboisomerase A
A6A12_RS11900	ENOG4108JQ1	Dehydrogenase
A6A12_RS11905	ENOG4108ZP8	Acetolactate synthase small subunit
A6A12_RS11910	ENOG4105C7K	acetolactate synthase
A6A12_RS11915	ENOG4108IQE	Amp-dependent synthetase and ligase
A6A12_RS11920	ENOG41064T2	transcriptional regulator, lysR family
A6A12_RS11945	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A6A12_RS11950	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A6A12_RS12005	ENOG4108K5H	permease YjgP YjgQ family protein
A6A12_RS12010	ENOG4108M8S	permease YjgP YjgQ family protein
A6A12_RS12015	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A6A12_RS12020	ENOG4105MYG	DNA polymerase iii, chi subunit
A6A12_RS12025	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A6A12_RS12030	ENOG4105C5I	Dehydrogenase
A6A12_RS12035	ENOG4105D3G	Pseudouridine synthase
A6A12_RS12040	ENOG4105K3M	)-transporter
A6A12_RS12045	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
A6A12_RS12055	ENOG4108IAB	Phoh family
A6A12_RS12060	ENOG4105DBV	ornithine carbamoyltransferase
A6A12_RS12065	ENOG4105CXT	aspartate transcarbamylase
A6A12_RS12070	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
A6A12_RS12075	ENOG4105KME	endoribonuclease L-psp
A6A12_RS12090	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
A6A12_RS12095	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A6A12_RS12100	ENOG4105VFK	BolA family
A6A12_RS12110	ENOG4105E3I	toluene tolerance
A6A12_RS12115	ENOG4107PE3	Mammalian cell entry related domain protein
A6A12_RS12120	ENOG4105CY3	ABC transporter, permease
A6A12_RS12125	ENOG4105DHJ	ABC, transporter
A6A12_RS12135	ENOG4105C2X	Arabinose 5-phosphate isomerase
A6A12_RS12140	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
A6A12_RS12150	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
A6A12_RS12155	ENOG4108IUZ	ABC transporter
A6A12_RS12160	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6A12_RS12165	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
A6A12_RS12170	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
A6A12_RS12175	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
A6A12_RS12180	ENOG41080Z8	PHOSPHOCARRIER protein
A6A12_RS12185	ENOG4105CJW	magnesium transporter
A6A12_RS12190	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
A6A12_RS12195	ENOG4105N42	UPF0307 protein
A6A12_RS12200	ENOG4107T0D	ABC, transporter
A6A12_RS12205	ENOG4106SMU	thiamine transporter membrane protein
A6A12_RS12215	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A6A12_RS12220	ENOG4105DFU	Cell wall formation (By similarity)
A6A12_RS12225	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
A6A12_RS12230	ENOG4105F0N	pyrophosphate phospho-hydrolase
A6A12_RS12240	ENOG41066HZ	AIG2-like family
A6A12_RS12245	ENOG4105MA0	exported protein
A6A12_RS12250	ENOG4105CFU	surface antigen
A6A12_RS12255	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A6A12_RS12260	ENOG4108UUE	Transcriptional regulator
A6A12_RS12295	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
A6A12_RS12300	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
A6A12_RS12305	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A6A12_RS12310	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A6A12_RS12315	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
A6A12_RS12355	ENOG4105C1J	atp-dependent rna helicase
A6A12_RS12360	ENOG4107YB6	acetyltransferase, (GNAT) family
A6A12_RS12365	ENOG4108UBT	opacity-associated protein
A6A12_RS12370	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A6A12_RS12375	ENOG4108ZT0	50S ribosomal protein l17
A6A12_RS12380	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A6A12_RS12385	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A6A12_RS12390	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A6A12_RS12395	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A6A12_RS12405	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A6A12_RS12420	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A6A12_RS12430	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A6A12_RS12435	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A6A12_RS12460	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A6A12_RS12465	ENOG41083MP	50s ribosomal protein l29
A6A12_RS12475	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A6A12_RS12480	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A6A12_RS12485	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A6A12_RS12495	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A6A12_RS12500	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A6A12_RS12505	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A6A12_RS12510	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A6A12_RS12515	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A6A12_RS12520	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A6A12_RS12525	ENOG4108UV7	flagellar protein motX
A6A12_RS12535	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A6A12_RS12540	ENOG4105D44	asparaginase
A6A12_RS12545	ENOG4108YZY	peptidylprolyl cis-trans isomerase
A6A12_RS12550	ENOG4105VKU	nucleicacid-binding protein
A6A12_RS12560	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
A6A12_RS12565	ENOG4105C5H	ABC transporter
A6A12_RS12575	ENOG4105DNZ	Alpha Beta Hydrolase
A6A12_RS12580	ENOG4105YP7	UPF0270 protein
A6A12_RS12585	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
A6A12_RS12600	ENOG4105C26	Dehydrogenase
A6A12_RS12615	ENOG4105DDQ	anthranilate synthase
A6A12_RS12635	ENOG4105CR8	Transcriptional regulator
A6A12_RS12650	ENOG4105C31	Tryptophanyl-tRNA synthetase
A6A12_RS12655	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A6A12_RS12660	ENOG4105DJV	ribulose-phosphate 3-epimerase
A6A12_RS12665	ENOG4105DFE	Dna adenine methylase
A6A12_RS12675	ENOG4105D49	3-dehydroquinate synthase
A6A12_RS12680	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A6A12_RS12685	ENOG4105E4G	Type IV pilus
A6A12_RS12710	ENOG4108JQC	penicillin-binding protein 1A
A6A12_RS12715	ENOG4105C5Q	Transcriptional regulator
A6A12_RS12720	ENOG4105EHV	domain protein
A6A12_RS12725	ENOG4107QN2	dihydrolipoyl dehydrogenase
A6A12_RS12735	ENOG4105CH7	arginosuccinase
A6A12_RS12745	ENOG4105CAS	nag kinase
A6A12_RS12750	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A6A12_RS12755	ENOG4105CWC	Acetylornithine deacetylase
A6A12_RS12760	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
A6A12_RS12770	ENOG4105D7W	serine acetyltransferase
A6A12_RS12775	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A6A12_RS12780	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
A6A12_RS12785	ENOG4107YZP	Rhodanese domain protein
A6A12_RS12790	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
A6A12_RS12805	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
A6A12_RS12810	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
A6A12_RS12815	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A6A12_RS12820	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
A6A12_RS12835	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A6A12_RS12875	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
A6A12_RS12880	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
A6A12_RS12900	ENOG4105ETE	Transcriptional regulator (LacI family
A6A12_RS12905	ENOG4105C25	Primosomal protein n'
A6A12_RS12910	ENOG4105VFB	Binds the 23S rRNA (By similarity)
A6A12_RS12915	ENOG4105C6K	Malic enzyme
A6A12_RS12920	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
A6A12_RS12925	ENOG4105C28	cystathionine
A6A12_RS12930	ENOG4105CFH	Aspartokinase
A6A12_RS12940	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
A6A12_RS12945	ENOG4105CBT	Fructose-1,6-bisphosphatase
A6A12_RS12950	ENOG4105CTQ	phosphohexokinase
A6A12_RS12955	ENOG41076HS	cation diffusion facilitator family transporter
A6A12_RS12965	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A6A12_RS12970	ENOG4105E0F	Histidine kinase
A6A12_RS12975	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
A6A12_RS12980	ENOG4105VEQ	Cold shock protein
A6A12_RS12985	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
A6A12_RS12990	ENOG4108IJ0	Aspartate ammonia-lyase
A6A12_RS12995	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
A6A12_RS13000	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
A6A12_RS13005	ENOG4105CEU	Arginine dihydrolase
A6A12_RS13015	ENOG4105DBV	ornithine carbamoyltransferase
A6A12_RS13025	ENOG4105CXT	aspartate transcarbamylase
A6A12_RS13030	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
A6A12_RS13035	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
A6A12_RS13040	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
A6A12_RS13060	ENOG4107QN1	sodium solute
A6A12_RS13065	ENOG4105BZU	Histidine kinase
A6A12_RS13070	ENOG4105D8G	Major Facilitator superfamily
A6A12_RS13090	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A6A12_RS13095	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
A6A12_RS13100	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A6A12_RS13110	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A6A12_RS13115	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
A6A12_RS13125	ENOG4105W1Y	Transcriptional regulator
A6A12_RS13145	ENOG4105K70	DNA-binding protein
A6A12_RS13155	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
A6A12_RS13160	ENOG4105R2J	Conserved Protein
A6A12_RS13165	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
A6A12_RS13170	ENOG4105CUY	Mechanosensitive ion channel
A6A12_RS13175	ENOG4105C8Q	Methyl-accepting chemotaxis
A6A12_RS13180	ENOG4105CY0	Metallo-Beta-Lactamase
A6A12_RS13185	ENOG4105ESV	Glycosyl transferase, family 4
A6A12_RS13200	ENOG4107T8Q	Glycosyl transferase (Group 1
A6A12_RS13205	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A6A12_RS13240	ENOG4107ZF2	Phosphatase
A6A12_RS13245	ENOG4105DAY	polysaccharide export protein
A6A12_RS13255	ENOG4108MDC	(LipO)protein
A6A12_RS13265	ENOG4105E3R	(LipO)protein
A6A12_RS13275	ENOG4105D3Q	Sugar transferase
A6A12_RS13295	ENOG4105H63	Glycosyl transferase, family 2
A6A12_RS13300	ENOG4106IQQ	
A6A12_RS13330	ENOG4105CKK	Glycosyl transferase, family 2
A6A12_RS13340	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A6A12_RS13350	ENOG4105C7K	acetolactate synthase
A6A12_RS13355	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A6A12_RS13360	ENOG4105FAW	cDP-glucose 4,6-dehydratase
A6A12_RS13365	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
A6A12_RS13390	ENOG4105EY8	ABC transporter
A6A12_RS13400	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A6A12_RS13410	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
A6A12_RS13415	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A6A12_RS13420	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
A6A12_RS13430	ENOG4105PF3	O-Antigen polymerase
A6A12_RS13435	ENOG4105XA0	heptosyltransferase ii
A6A12_RS13445	ENOG4108ST3	glycosyltransferase
A6A12_RS13450	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
A6A12_RS13455	ENOG4108UT6	Transferase hexapeptide repeat containing protein
A6A12_RS13460	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A6A12_RS13475	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
A6A12_RS13480	ENOG4105DKP	glycosyl transferase, family 9
A6A12_RS13485	ENOG4106WTF	Glycosyl transferase, family 2
A6A12_RS13490	ENOG4105M5K	heptosyltransferase
A6A12_RS13495	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
A6A12_RS13500	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
A6A12_RS13510	ENOG4105W0E	50S ribosomal protein L33
A6A12_RS13515	ENOG4105KDC	50s ribosomal protein l28
A6A12_RS13520	ENOG4105W5Q	DNA repair protein (RadC
A6A12_RS13525	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A6A12_RS13530	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
A6A12_RS13535	ENOG4105D1S	lipid A biosynthesis
A6A12_RS13540	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
A6A12_RS13545	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A6A12_RS13550	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A6A12_RS13555	ENOG4105DSJ	YicC domain protein
A6A12_RS13695	ENOG4107RAN	Peptidase, M16
A6A12_RS13710	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
A6A12_RS13715	ENOG4105J76	Periplasmic binding protein
A6A12_RS13720	ENOG4105E0A	ABC, transporter
A6A12_RS13725	ENOG4105E0K	tonB-dependent siderophore receptor
A6A12_RS13730	ENOG4105BZ1	(ABC) transporter
A6A12_RS13735	ENOG4105C5Y	PTS System
A6A12_RS13740	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A6A12_RS13745	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
A6A12_RS13760	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A6A12_RS13765	ENOG4105FR1	rard protein
A6A12_RS13775	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
A6A12_RS13780	ENOG4105C4R	Atp-dependent dna helicase
A6A12_RS13785	ENOG4105DGW	oligopeptidase A
A6A12_RS13790	ENOG4105D6S	protein involved in catabolism of external DNA
A6A12_RS13795	ENOG4105DC8	reductase
A6A12_RS13835	ENOG4105DB4	
A6A12_RS13865	ENOG4106V8H	Nucleoid-associated protein
A6A12_RS13925	ENOG4108VYJ	response regulator receiver protein
A6A12_RS13940	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A6A12_RS13945	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A6A12_RS13985	ENOG4105MPD	Cytochrome
A6A12_RS13990	ENOG4105C4R	Atp-dependent dna helicase
A6A12_RS13995	ENOG4107Z3H	Transcriptional regulator, TetR family
A6A12_RS14000	ENOG410624X	efflux transporter, rnd family, mfp subunit
A6A12_RS14005	ENOG4105BZS	acriflavin resistance protein
A6A12_RS14010	ENOG4105W0Z	cytoplasmic protein
A6A12_RS14020	ENOG4105EMY	transcriptional regulator
A6A12_RS14025	ENOG4105D4P	Coproporphyrinogen iii oxidase
A6A12_RS14030	ENOG4105XCT	Protein of unknown function (DUF2489)
A6A12_RS14045	ENOG4106RE7	Cytochrome
A6A12_RS14055	ENOG4105C2M	dna polymerase I
A6A12_RS14060	ENOG4105D52	delta-aminolevulinic acid dehydratase
A6A12_RS14065	ENOG4105F8V	Hydrolase, tatD family
A6A12_RS14075	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A6A12_RS14080	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
A6A12_RS14090	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
A6A12_RS14095	ENOG4105JC1	sterol-binding domain protein
A6A12_RS14105	ENOG4105CGY	Dna recombination protein
A6A12_RS14125	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
A6A12_RS14135	ENOG4105EF1	ribulokinase
A6A12_RS14140	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
A6A12_RS14145	ENOG4105C2J	ABC transporter
A6A12_RS14150	ENOG4105CNN	ABC, transporter
A6A12_RS14160	ENOG4105CBX	hi0933 family
A6A12_RS14170	ENOG4108V6B	universal stress protein B
A6A12_RS14175	ENOG41090A1	ferritin
A6A12_RS14180	ENOG4108M6U	Universal stress protein A
A6A12_RS14185	ENOG4105EMK	carboxylate amino acid amine transporter
A6A12_RS14195	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
A6A12_RS14200	ENOG4108VVK	transcriptional Regulator, AsnC
A6A12_RS14215	ENOG4105CNH	Multidrug resistance protein MdtL
A6A12_RS14220	ENOG4105G2Y	Transcriptional regulator
A6A12_RS14225	ENOG4105DC7	peptidase M24
A6A12_RS14225	ENOG4105DC7	peptidase M24
A6A12_RS14230	ENOG4105D41	biosynthesis protein thiH
A6A12_RS14240	ENOG4105WHD	thiamine biosynthesis protein ThiS
A6A12_RS14245	ENOG4105D06	uba thif-type nad fad binding protein
A6A12_RS14250	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A6A12_RS14260	ENOG4105WMR	Protein CrcB homolog
A6A12_RS14305	ENOG4108RR8	protoporphyrinogen oxidase
A6A12_RS14310	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A6A12_RS14315	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A6A12_RS14320	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A6A12_RS14325	ENOG4105CHU	acetyl-coa acetyltransferase
A6A12_RS14330	ENOG4105F52	Transcriptional regulator
A6A12_RS14335	ENOG4105CZQ	inner membrane transport protein YdhC
A6A12_RS14340	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A6A12_RS14345	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A6A12_RS14350	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A6A12_RS14355	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A6A12_RS14360	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A6A12_RS14365	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A6A12_RS14375	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A6A12_RS14385	ENOG410684E	atp synthase
A6A12_RS14390	ENOG4105FA0	parb-like partition protein
A6A12_RS14395	ENOG4107QJE	Chromosome Partitioning Protein
A6A12_RS14400	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
A6A12_RS14405	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
A6A12_RS14410	ENOG4105QTB	Flavodoxin
A6A12_RS14415	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
A6A12_RS14420	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
A6A12_RS14430	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
A6A12_RS14440	ENOG4105CDA	abc transporter atp-binding protein
A6A12_RS14445	ENOG4105E5Q	amino acid AbC transporter
A6A12_RS14450	ENOG4105EAB	amino acid AbC transporter