locus-tag	class	description
VEA_RS00010	COG0405	Gamma-glutamyltransferase
VEA_RS00020	COG3267	Type II secretory pathway component ExeA
VEA_RS00020	COG3409	Peptidoglycan-binding domain 1 protein
VEA_RS00030	COG1968	undecaprenyl-diphosphatase activity
VEA_RS00035	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VEA_RS00040	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VEA_RS00045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VEA_RS00050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
VEA_RS00055	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VEA_RS00060	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VEA_RS00065	COG1610	YqeY-like protein
VEA_RS00070	COG0358	DNA primase activity
VEA_RS00115	COG2213	PTS system mannitol-specific
VEA_RS00115	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VEA_RS00125	COG3722	fumarate hydratase activity
VEA_RS00140	COG1461	Dihydroxyacetone kinase
VEA_RS00145	COG2376	Dihydroxyacetone kinase
VEA_RS00155	COG5002	protein histidine kinase activity
VEA_RS00170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VEA_RS00175	COG1349	DNA-binding transcription factor activity
VEA_RS00180	COG0469	pyruvate kinase activity
VEA_RS00200	COG0028	Belongs to the TPP enzyme family
VEA_RS00205	COG1022	Amp-dependent synthetase and ligase
VEA_RS00210	COG0583	DNA-binding transcription factor activity
VEA_RS00230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VEA_RS00235	COG0473	3-isopropylmalate dehydrogenase activity
VEA_RS00255	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VEA_RS00260	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VEA_RS00265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VEA_RS00270	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VEA_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VEA_RS00280	COG2967	ApaG domain
VEA_RS00285	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VEA_RS00300	COG2966	Psort location CytoplasmicMembrane, score
VEA_RS00305	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VEA_RS00315	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VEA_RS00320	COG0142	geranyltranstransferase activity
VEA_RS00340	COG2358	TRAP transporter, solute receptor (TAXI family
VEA_RS00360	COG1902	pentaerythritol trinitrate reductase activity
VEA_RS00365	COG0583	DNA-binding transcription factor activity
VEA_RS00370	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VEA_RS00375	COG1178	ABC-type Fe3 transport system permease component
VEA_RS00380	COG4143	(ABC) transporter
VEA_RS00385	COG0163	prenyltransferase activity
VEA_RS00390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VEA_RS00395	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VEA_RS00400	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VEA_RS00410	COG2105	PFAM AIG2 family protein
VEA_RS00415	COG2911	Protein conserved in bacteria
VEA_RS00420	COG0729	surface antigen
VEA_RS00425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VEA_RS00435	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VEA_RS00450	COG4181	ATPase activity
VEA_RS00470	COG0529	Catalyzes the synthesis of activated sulfate
VEA_RS00475	COG0471	metal ion transport
VEA_RS00475	COG3273	potassium ion transport
VEA_RS00480	COG2895	sulfate adenylyltransferase (ATP) activity
VEA_RS00485	COG0175	sulfate reduction
VEA_RS00490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VEA_RS00490	COG1648	precorrin-2 dehydrogenase activity
VEA_RS00505	COG0513	Belongs to the DEAD box helicase family
VEA_RS00510	COG2153	protein acetylation
VEA_RS00520	COG0545	Peptidyl-prolyl cis-trans isomerase
VEA_RS00530	COG0203	ribosomal protein L17
VEA_RS00535	COG0202	RNA polymerase activity
VEA_RS00545	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VEA_RS00550	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VEA_RS00555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VEA_RS00560	COG0201	protein transport
VEA_RS00565	COG0200	Binds to the 23S rRNA
VEA_RS00570	COG1841	ribosomal large subunit assembly
VEA_RS00585	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VEA_RS00590	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VEA_RS00595	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VEA_RS00600	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VEA_RS00605	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VEA_RS00615	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VEA_RS00620	COG0255	Belongs to the universal ribosomal protein uL29 family
VEA_RS00630	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VEA_RS00635	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VEA_RS00640	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VEA_RS00645	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VEA_RS00655	COG0088	Forms part of the polypeptide exit tunnel
VEA_RS00660	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VEA_RS00670	COG0254	rRNA binding
VEA_RS00675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VEA_RS00680	COG1609	Transcriptional regulator
VEA_RS00690	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VEA_RS00695	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VEA_RS00700	COG1575	Belongs to the MenA family. Type 1 subfamily
VEA_RS00705	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VEA_RS00715	COG1494	fructose-1,6-bisphosphatase
VEA_RS00740	COG0149	triose-phosphate isomerase activity
VEA_RS00760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VEA_RS00770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VEA_RS00775	COG0438	transferase activity, transferring glycosyl groups
VEA_RS00785	COG1216	Glycosyl transferase, family 2
VEA_RS00785	COG1442	glycosyl transferase family 8
VEA_RS00800	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VEA_RS00805	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VEA_RS00810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VEA_RS00815	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VEA_RS00820	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VEA_RS00860	COG0517	IMP dehydrogenase activity
VEA_RS00860	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VEA_RS00895	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VEA_RS00905	COG1560	Kdo2-lipid A biosynthetic process
VEA_RS00910	COG0859	PFAM glycosyl transferase family 9
VEA_RS00915	COG1519	Transferase
VEA_RS00925	COG1083	cytidylyl-transferase
VEA_RS00930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
VEA_RS00940	COG2089	acid synthase
VEA_RS00945	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VEA_RS00950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VEA_RS00955	COG1086	Polysaccharide biosynthesis protein
VEA_RS00965	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VEA_RS00985	COG3642	lipopolysaccharide core region biosynthetic process
VEA_RS00990	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VEA_RS00995	COG0859	PFAM glycosyl transferase family 9
VEA_RS01000	COG0463	Glycosyl transferase, family 2
VEA_RS01045	COG2003	Belongs to the UPF0758 family
VEA_RS01050	COG0840	transmembrane signaling receptor activity
VEA_RS01055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VEA_RS01060	COG1309	transcriptional regulator
VEA_RS01065	COG1560	Kdo2-lipid A biosynthetic process
VEA_RS01070	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VEA_RS01075	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VEA_RS01080	COG1561	YicC-like family, N-terminal region
VEA_RS01115	COG0328	RNA-DNA hybrid ribonuclease activity
VEA_RS01120	COG2003	Belongs to the UPF0758 family
VEA_RS01175	COG5001	Diguanylate cyclase
VEA_RS01185	COG4608	Belongs to the ABC transporter superfamily
VEA_RS01190	COG0444	Belongs to the ABC transporter superfamily
VEA_RS01195	COG0747	negative chemotaxis
VEA_RS01200	COG4239	(ABC) transporter, permease
VEA_RS01205	COG4174	ABC transporter (Permease)
VEA_RS01225	COG0811	peptide transport
VEA_RS01230	COG0848	biopolymer transport protein
VEA_RS01245	COG0194	GDP metabolic process
VEA_RS01250	COG1758	RNA polymerase activity
VEA_RS01255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VEA_RS01260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VEA_RS01265	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VEA_RS01270	COG2233	PERMEase
VEA_RS01290	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VEA_RS01300	COG2183	response to ionizing radiation
VEA_RS01310	COG0596	Alpha beta hydrolase
VEA_RS01315	COG1040	competence protein
VEA_RS01320	COG0316	Belongs to the HesB IscA family
VEA_RS01320	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
VEA_RS01325	COG0494	nUDIX hydrolase
VEA_RS01330	COG1218	3'(2'),5'-bisphosphate nucleotidase
VEA_RS01340	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VEA_RS01345	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VEA_RS01350	COG3156	type II secretion system protein K
VEA_RS01355	COG4795	General secretion pathway protein
VEA_RS01360	COG2165	general secretion pathway protein
VEA_RS01365	COG2165	general secretion pathway protein
VEA_RS01370	COG2165	general secretion pathway protein
VEA_RS01375	COG1459	type II secretion system
VEA_RS01380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VEA_RS01390	COG3031	protein transport across the cell outer membrane
VEA_RS01395	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VEA_RS01400	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VEA_RS01405	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VEA_RS01415	COG0456	acetyltransferase
VEA_RS01420	COG1490	D-aminoacyl-tRNA deacylase activity
VEA_RS01425	COG1295	ribonuclease BN
VEA_RS01440	COG1217	gtp-binding protein TYPA
VEA_RS01445	COG0174	glutamine synthetase
VEA_RS01455	COG3852	Histidine kinase
VEA_RS01460	COG2204	response regulator
VEA_RS01470	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VEA_RS01500	COG0218	Necessary for normal cell division and for the maintenance of normal septation
VEA_RS01505	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VEA_RS01505	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VEA_RS01510	COG0456	acetyltransferase
VEA_RS01520	COG0084	hydrolase, TatD family'
VEA_RS01525	COG0805	protein transport
VEA_RS01530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VEA_RS01540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VEA_RS01545	COG3165	ubiquinone biosynthetic process from chorismate
VEA_RS01550	COG2226	methyltransferase
VEA_RS01555	COG1322	Protein conserved in bacteria
VEA_RS01570	COG0628	permease
VEA_RS01600	COG1597	lipid kinase activity
VEA_RS01630	COG2081	HI0933 family
VEA_RS01640	COG1528	Iron-storage protein
VEA_RS01645	COG0589	response to stress
VEA_RS01660	COG0742	ribosomal rna small subunit methyltransferase
VEA_RS01665	COG5001	Diguanylate cyclase
VEA_RS01665	COG5002	protein histidine kinase activity
VEA_RS01670	COG1522	sequence-specific DNA binding
VEA_RS01680	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VEA_RS01685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VEA_RS01690	COG0583	DNA-binding transcription factor activity
VEA_RS01695	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
VEA_RS01700	COG0800	Aldolase
VEA_RS01705	COG2610	gluconate transmembrane transporter activity
VEA_RS01710	COG3265	gluconokinase activity
VEA_RS01715	COG0129	dihydroxy-acid dehydratase activity
VEA_RS01730	COG0583	DNA-binding transcription factor activity
VEA_RS01735	COG1609	Transcriptional regulator
VEA_RS01770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VEA_RS01775	COG0601	transmembrane transport
VEA_RS01780	COG4166	transmembrane transport
VEA_RS01835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VEA_RS01840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VEA_RS01845	COG2960	long-chain fatty acid transporting porin activity
VEA_RS01850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VEA_RS01855	COG0583	DNA-binding transcription factor activity
VEA_RS01895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VEA_RS01900	COG1739	Uncharacterized protein family UPF0029
VEA_RS01910	COG0183	Belongs to the thiolase family
VEA_RS01915	COG0604	alcohol dehydrogenase
VEA_RS01930	COG0425	Belongs to the sulfur carrier protein TusA family
VEA_RS01940	COG2119	membrane
VEA_RS01955	COG0366	Alpha amylase catalytic
VEA_RS01960	COG3977	Valine--pyruvate aminotransferase
VEA_RS01965	COG0071	Belongs to the small heat shock protein (HSP20) family
VEA_RS01980	COG0187	DNA topoisomerase II activity
VEA_RS01990	COG0592	DNA-directed DNA polymerase activity
VEA_RS01995	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VEA_RS02010	COG1126	abc transporter atp-binding protein
VEA_RS02020	COG0594	ribonuclease P activity
VEA_RS02025	COG0706	membrane insertase activity
VEA_RS02035	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VEA_RS02040	COG0445	tRNA wobble uridine modification
VEA_RS02045	COG0357	Ribosomal RNA small subunit methyltransferase G
VEA_RS02050	COG1192	Involved in chromosome partitioning
VEA_RS02055	COG1475	DNA binding
VEA_RS02060	COG3312	ion transport
VEA_RS02065	COG0356	it plays a direct role in the translocation of protons across the membrane
VEA_RS02075	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VEA_RS02080	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VEA_RS02085	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VEA_RS02090	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VEA_RS02095	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VEA_RS02100	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VEA_RS02110	COG0765	amino acid transport
VEA_RS02120	COG2814	Major facilitator Superfamily
VEA_RS02125	COG0583	DNA-binding transcription factor activity
VEA_RS02135	COG0129	dihydroxy-acid dehydratase activity
VEA_RS02140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VEA_RS02145	COG3978	acetolactate synthase activity
VEA_RS02155	COG0606	chelatase, subunit chli
VEA_RS02165	COG0204	Acyl-transferase
VEA_RS02170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VEA_RS02175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VEA_RS02185	COG3084	Protein conserved in bacteria
VEA_RS02190	COG4326	sporulation control protein
VEA_RS02195	COG1272	protein, Hemolysin III
VEA_RS02205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VEA_RS02210	COG0569	domain protein
VEA_RS02215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VEA_RS02215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VEA_RS02220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VEA_RS02225	COG0242	peptide deformylase activity
VEA_RS02235	COG0758	DNA mediated transformation
VEA_RS02240	COG2922	Belongs to the Smg family
VEA_RS02245	COG0551	DNA topoisomerase type I activity
VEA_RS02250	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VEA_RS02255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VEA_RS02260	COG0009	L-threonylcarbamoyladenylate synthase
VEA_RS02265	COG0408	coproporphyrinogen oxidase activity
VEA_RS02270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VEA_RS02280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VEA_RS02330	COG2132	Multicopper oxidase
VEA_RS02335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VEA_RS02350	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VEA_RS02355	COG2104	thiamine diphosphate biosynthetic process
VEA_RS02370	COG0006	proline dipeptidase activity
VEA_RS02370	COG0006	proline dipeptidase activity
VEA_RS02400	COG3220	belongs to the UPF0276 family
VEA_RS02410	COG0210	DNA helicase
VEA_RS02415	COG0405	Gamma-glutamyltransferase
VEA_RS02420	COG1280	lysine exporter protein (LysE YggA)
VEA_RS02430	COG2962	Rard protein
VEA_RS02435	COG0514	ATP-dependent DNA helicase (RecQ)
VEA_RS02445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VEA_RS02450	COG0248	Ppx GppA phosphatase
VEA_RS02455	COG0513	Belongs to the DEAD box helicase family
VEA_RS02460	COG3118	belongs to the thioredoxin family
VEA_RS02475	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VEA_RS02480	COG0633	Ferredoxin
VEA_RS02520	COG3071	HemY protein
VEA_RS02525	COG2959	enzyme of heme biosynthesis
VEA_RS02530	COG1587	Uroporphyrinogen-III synthase
VEA_RS02535	COG0181	hydroxymethylbilane synthase activity
VEA_RS02540	COG3072	Adenylate cyclase
VEA_RS02545	COG1965	Belongs to the frataxin family
VEA_RS02555	COG0019	diaminopimelate decarboxylase activity
VEA_RS02560	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VEA_RS02570	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VEA_RS02575	COG1011	Hydrolase
VEA_RS02580	COG2200	EAL domain
VEA_RS02580	COG3287	FIST C domain
VEA_RS02580	COG2199	diguanylate cyclase activity
VEA_RS02585	COG3148	PFAM DTW domain containing protein
VEA_RS02600	COG0561	phosphatase activity
VEA_RS02605	COG2267	carboxylic ester hydrolase activity
VEA_RS02610	COG1280	lysine exporter protein (LysE YggA)
VEA_RS02615	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VEA_RS02620	COG0640	Transcriptional regulator
VEA_RS02625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VEA_RS02670	COG2095	MarC family integral membrane protein
VEA_RS02680	COG0742	ribosomal rna small subunit methyltransferase
VEA_RS02685	COG0552	protein localization to endoplasmic reticulum
VEA_RS02690	COG2884	Cell division ATP-binding protein ftsE
VEA_RS02695	COG2177	Part of the ABC transporter FtsEX involved in
VEA_RS02705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VEA_RS02710	COG0705	Rhomboid family
VEA_RS02715	COG1580	Controls the rotational direction of flagella during chemotaxis
VEA_RS02720	COG3161	chorismate lyase activity
VEA_RS02725	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VEA_RS02730	COG2937	Belongs to the GPAT DAPAT family
VEA_RS02735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VEA_RS02740	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
VEA_RS02745	COG0534	Mate efflux family protein
VEA_RS02750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VEA_RS02770	COG4206	TonB-dependent receptor
VEA_RS02810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VEA_RS02820	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VEA_RS02825	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
VEA_RS02825	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
VEA_RS02855	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VEA_RS02860	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VEA_RS02865	COG0250	Participates in transcription elongation, termination and antitermination
VEA_RS02880	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VEA_RS02885	COG0222	ribosome binding
VEA_RS02890	COG0085	RNA polymerase activity
VEA_RS02895	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VEA_RS02900	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VEA_RS02905	COG2816	NAD+ diphosphatase activity
VEA_RS02910	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VEA_RS02915	COG1573	uracil-dna glycosylase
VEA_RS02925	COG3068	Protein conserved in bacteria
VEA_RS02930	COG1253	flavin adenine dinucleotide binding
VEA_RS02945	COG0151	Belongs to the GarS family
VEA_RS02950	COG0138	bifunctional purine biosynthesis protein purh
VEA_RS02955	COG0789	Transcriptional regulator
VEA_RS02960	COG3710	Transcriptional regulator
VEA_RS02965	COG0531	amino acid
VEA_RS02970	COG1982	Orn Lys Arg decarboxylase major
VEA_RS03030	COG0488	(ABC) transporter
VEA_RS03040	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VEA_RS03045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VEA_RS03050	COG2264	protein methyltransferase activity
VEA_RS03055	COG0439	Biotin carboxylase
VEA_RS03060	COG0511	ligase activity, forming carbon-carbon bonds
VEA_RS03065	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VEA_RS03070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VEA_RS03085	COG2814	Major facilitator Superfamily
VEA_RS03110	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VEA_RS03120	COG3263	regulation of cellular component size
VEA_RS03130	COG4232	protein-disulfide reductase activity
VEA_RS03135	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VEA_RS03140	COG1027	Aspartate ammonia-lyase
VEA_RS03150	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VEA_RS03160	COG2205	protein histidine kinase activity
VEA_RS03165	COG0745	RESPONSE REGULATOR receiver
VEA_RS03170	COG3678	ATP-independent chaperone mediated protein folding
VEA_RS03175	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VEA_RS03180	COG0205	6-phosphofructokinase activity
VEA_RS03185	COG0534	Mate efflux family protein
VEA_RS03195	COG0459	protein refolding
VEA_RS03220	COG1285	pathogenesis
VEA_RS03225	COG1509	lysine 2,3-aminomutase activity
VEA_RS03245	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VEA_RS03250	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VEA_RS03255	COG1053	succinate dehydrogenase
VEA_RS03260	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VEA_RS03280	COG4942	peptidase
VEA_RS03285	COG1045	serine acetyltransferase
VEA_RS03290	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VEA_RS03295	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VEA_RS03300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VEA_RS03305	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VEA_RS03315	COG3273	potassium ion transport
VEA_RS03315	COG0471	metal ion transport
VEA_RS03320	COG0688	phosphatidylethanolamine metabolic process
VEA_RS03325	COG1162	GTPase activity
VEA_RS03330	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VEA_RS03395	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VEA_RS03400	COG0802	atpase or kinase
VEA_RS03410	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VEA_RS03415	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VEA_RS03425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VEA_RS03430	COG0330	HflC and HflK could
VEA_RS03435	COG0330	HflC and HflK could
VEA_RS03440	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VEA_RS03445	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VEA_RS03450	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VEA_RS03455	COG1017	nitric oxide dioxygenase activity
VEA_RS03455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VEA_RS03460	COG1959	2 iron, 2 sulfur cluster binding
VEA_RS03465	COG0557	exoribonuclease II activity
VEA_RS03470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VEA_RS03475	COG0546	phosphoglycolate phosphatase activity
VEA_RS03480	COG0180	Tryptophanyl-tRNA synthetase
VEA_RS03495	COG0512	Glutamine amidotransferase of anthranilate synthase
VEA_RS03500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VEA_RS03520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VEA_RS03525	COG3954	Phosphoribulokinase
VEA_RS03530	COG3089	Belongs to the UPF0270 family
VEA_RS03535	COG0429	hydrolase of the alpha beta-hydrolase fold
VEA_RS03545	COG0488	(ABC) transporter
VEA_RS03550	COG2249	NAD(P)H dehydrogenase (quinone) activity
VEA_RS03565	COG1047	Peptidyl-prolyl cis-trans
VEA_RS03570	COG1446	asparaginase
VEA_RS03585	COG0545	Peptidyl-prolyl cis-trans isomerase
VEA_RS03590	COG2964	Protein conserved in bacteria
VEA_RS03595	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VEA_RS03600	COG2923	Belongs to the DsrF TusC family
VEA_RS03605	COG2168	tRNA wobble position uridine thiolation
VEA_RS03620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VEA_RS03625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VEA_RS03630	COG2906	2 iron, 2 sulfur cluster binding
VEA_RS03640	COG0281	malic enzyme
VEA_RS03645	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VEA_RS03650	COG0626	cystathionine gamma-synthase activity
VEA_RS03655	COG0527	aspartate kinase activity
VEA_RS03655	COG0460	homoserine dehydrogenase
VEA_RS03660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VEA_RS03670	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VEA_RS03680	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VEA_RS03690	COG0137	argininosuccinate synthase activity
VEA_RS03695	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VEA_RS03695	COG0165	Argininosuccinate lyase
VEA_RS03710	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VEA_RS03710	COG0678	peroxiredoxin activity
VEA_RS03720	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VEA_RS03750	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VEA_RS03755	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VEA_RS03765	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VEA_RS03770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VEA_RS03775	COG0360	Binds together with S18 to 16S ribosomal RNA
VEA_RS03780	COG2965	DNA replication, synthesis of RNA primer
VEA_RS03805	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VEA_RS03810	COG0432	Pfam Uncharacterised protein family UPF0047
VEA_RS03815	COG0166	Belongs to the GPI family
VEA_RS03825	COG0735	belongs to the Fur family
VEA_RS03830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VEA_RS03850	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VEA_RS03855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VEA_RS03860	COG0175	sulfate reduction
VEA_RS03920	COG1410	methionine synthase
VEA_RS03920	COG0646	methionine synthase
VEA_RS03925	COG0527	aspartate kinase activity
VEA_RS03935	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VEA_RS03945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VEA_RS03960	COG0629	single-stranded DNA binding
VEA_RS03965	COG2199	diguanylate cyclase activity
VEA_RS03965	COG2200	EAL domain
VEA_RS03985	COG1450	Type ii and iii secretion system protein
VEA_RS03990	COG3267	Type II secretory pathway component ExeA
VEA_RS03990	COG3409	Peptidoglycan-binding domain 1 protein
VEA_RS04000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VEA_RS04005	COG1459	type II secretion system
VEA_RS04050	COG1077	Cell shape determining protein MreB Mrl
VEA_RS04055	COG1792	Involved in formation and maintenance of cell shape
VEA_RS04060	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VEA_RS04065	COG0424	maF-like protein
VEA_RS04075	COG3164	Protein of unknown function
VEA_RS04080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VEA_RS04085	COG0312	modulator of DNA gyrase
VEA_RS04090	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VEA_RS04095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VEA_RS04105	COG0564	pseudouridine synthase activity
VEA_RS04110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VEA_RS04115	COG3028	Belongs to the UPF0307 family
VEA_RS04120	COG0312	modulator of DNA gyrase
VEA_RS04125	COG2239	Acts as a magnesium transporter
VEA_RS04130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VEA_RS04135	COG1660	Displays ATPase and GTPase activities
VEA_RS04140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VEA_RS04145	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VEA_RS04155	COG1137	ATPase activity
VEA_RS04160	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VEA_RS04170	COG0517	IMP dehydrogenase activity
VEA_RS04170	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VEA_RS04180	COG1127	ABC transporter
VEA_RS04185	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VEA_RS04190	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VEA_RS04195	COG2854	intermembrane phospholipid transfer
VEA_RS04205	COG5007	Belongs to the BolA IbaG family
VEA_RS04215	COG0204	Acyl-transferase
VEA_RS04220	COG0251	oxidation-reduction process
VEA_RS04225	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
VEA_RS04230	COG0540	Belongs to the ATCase OTCase family
VEA_RS04270	COG0525	valine-tRNA ligase activity
VEA_RS04275	COG2927	DNA polymerase III (CHI subunit)
VEA_RS04285	COG0795	lipopolysaccharide-transporting ATPase activity
VEA_RS04290	COG0795	lipopolysaccharide-transporting ATPase activity
VEA_RS04305	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_RS04315	COG0726	polysaccharide deacetylase
VEA_RS04320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VEA_RS04325	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VEA_RS04330	COG1447	Phosphotransferase system cellobiose-specific component IIA
VEA_RS04335	COG1486	melibiose metabolic process
VEA_RS04340	COG3394	polysaccharide catabolic process
VEA_RS04350	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VEA_RS04395	COG1012	belongs to the aldehyde dehydrogenase family
VEA_RS04425	COG0840	transmembrane signaling receptor activity
VEA_RS04470	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VEA_RS04480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VEA_RS04490	COG2066	Belongs to the glutaminase family
VEA_RS04495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VEA_RS04500	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VEA_RS04510	COG1872	DUF167
VEA_RS04515	COG0762	integral membrane protein
VEA_RS04520	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VEA_RS04525	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VEA_RS04540	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VEA_RS04545	COG1678	Uncharacterized ACR, COG1678
VEA_RS04550	COG0189	ligase activity
VEA_RS04555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VEA_RS04560	COG2356	endonuclease I
VEA_RS04575	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VEA_RS04580	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VEA_RS04585	COG0583	DNA-binding transcription factor activity
VEA_RS04590	COG4771	TonB-dependent receptor
VEA_RS04595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VEA_RS04600	COG0126	phosphoglycerate kinase activity
VEA_RS04605	COG0191	fructose-bisphosphate aldolase activity
VEA_RS04610	COG0668	transmembrane transport
VEA_RS04625	COG0583	DNA-binding transcription factor activity
VEA_RS04635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VEA_RS04640	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VEA_RS04645	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VEA_RS04650	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VEA_RS04655	COG3079	Belongs to the UPF0149 family
VEA_RS04660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VEA_RS04665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VEA_RS04680	COG0354	folic acid binding
VEA_RS04685	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VEA_RS04690	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VEA_RS04695	COG1595	DNA-templated transcription, initiation
VEA_RS04710	COG3086	response to oxidative stress
VEA_RS04715	COG0481	GTPase activity
VEA_RS04720	COG0681	Belongs to the peptidase S26 family
VEA_RS04730	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VEA_RS04735	COG1381	Involved in DNA repair and RecF pathway recombination
VEA_RS04740	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VEA_RS04745	COG0736	holo-[acyl-carrier-protein] synthase activity
VEA_RS04755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VEA_RS04760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VEA_RS04765	COG3956	TIGRFAM MazG family protein
VEA_RS04770	COG0504	CTP synthase activity
VEA_RS04775	COG0148	phosphopyruvate hydratase activity
VEA_RS04780	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VEA_RS04785	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VEA_RS04800	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VEA_RS04805	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VEA_RS04815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VEA_RS04820	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VEA_RS04825	COG1546	Belongs to the CinA family
VEA_RS04830	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VEA_RS04835	COG2137	regulation of response to DNA damage stimulus
VEA_RS04840	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VEA_RS04845	COG0527	aspartate kinase activity
VEA_RS04910	COG3630	sodium ion export across plasma membrane
VEA_RS04915	COG5016	pyruvate
VEA_RS04915	COG0511	ligase activity, forming carbon-carbon bonds
VEA_RS04920	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VEA_RS04930	COG1238	metal cluster binding
VEA_RS04935	COG0612	Peptidase, M16
VEA_RS04950	COG1854	S-ribosylhomocysteine lyase activity
VEA_RS04955	COG4536	flavin adenine dinucleotide binding
VEA_RS04960	COG4137	Cytochrome C assembly protein
VEA_RS04965	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VEA_RS04970	COG0228	four-way junction DNA binding
VEA_RS04975	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VEA_RS04990	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
VEA_RS04995	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VEA_RS05000	COG0237	dephospho-CoA kinase activity
VEA_RS05010	COG1459	type II secretion system
VEA_RS05015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VEA_RS05020	COG4969	Belongs to the N-Me-Phe pilin family
VEA_RS05025	COG0157	Belongs to the NadC ModD family
VEA_RS05035	COG2186	Transcriptional regulator
VEA_RS05040	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VEA_RS05045	COG0508	dehydrogenase complex catalyzes the overall conversion of
VEA_RS05050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VEA_RS05065	COG0288	reversible hydration of carbon dioxide
VEA_RS05070	COG0659	secondary active sulfate transmembrane transporter activity
VEA_RS05075	COG1131	(ABC) transporter
VEA_RS05080	COG0842	Transport permease protein
VEA_RS05085	COG1560	Kdo2-lipid A biosynthetic process
VEA_RS05090	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VEA_RS05095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VEA_RS05100	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VEA_RS05110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VEA_RS05120	COG1489	DNA binding
VEA_RS05125	COG1643	Atp-dependent helicase
VEA_RS05130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VEA_RS05135	COG1752	Esterase of the alpha-beta hydrolase superfamily
VEA_RS05140	COG1049	propionate catabolic process, 2-methylcitrate cycle
VEA_RS05145	COG3112	Uncharacterised protein family (UPF0231)
VEA_RS05150	COG0347	Belongs to the P(II) protein family
VEA_RS05155	COG0004	ammonium transporteR
VEA_RS05160	COG1840	ABC-type Fe3 transport system, periplasmic component
VEA_RS05170	COG3842	ATPase activity
VEA_RS05175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VEA_RS05190	COG2971	BadF BadG BcrA BcrD
VEA_RS05200	COG4608	Belongs to the ABC transporter superfamily
VEA_RS05205	COG0444	Belongs to the ABC transporter superfamily
VEA_RS05210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VEA_RS05220	COG0747	negative chemotaxis
VEA_RS05225	COG0784	Response regulator, receiver
VEA_RS05225	COG2205	protein histidine kinase activity
VEA_RS05235	COG0628	permease
VEA_RS05240	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VEA_RS05260	COG0739	heme binding
VEA_RS05265	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VEA_RS05275	COG2027	D-alanyl-D-alanine carboxypeptidase
VEA_RS05280	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VEA_RS05285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VEA_RS05290	COG1534	Rna-binding protein
VEA_RS05295	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VEA_RS05300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VEA_RS05305	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VEA_RS05310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VEA_RS05315	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VEA_RS05330	COG0779	Required for maturation of 30S ribosomal subunits
VEA_RS05335	COG0195	Participates in both transcription termination and antitermination
VEA_RS05340	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VEA_RS05345	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VEA_RS05350	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
VEA_RS05355	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VEA_RS05360	COG1185	polyribonucleotide nucleotidyltransferase activity
VEA_RS05375	COG0534	Mate efflux family protein
VEA_RS05380	COG0826	peptidase U32
VEA_RS05385	COG0826	peptidase U32
VEA_RS05395	COG3154	lipid carrier protein
VEA_RS05400	COG3153	acetyltransferase
VEA_RS05420	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
VEA_RS05430	COG0084	hydrolase, TatD family'
VEA_RS05435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VEA_RS05445	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VEA_RS05450	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VEA_RS05455	COG0813	purine-nucleoside phosphorylase activity
VEA_RS05465	COG0560	Phosphoserine phosphatase
VEA_RS05475	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VEA_RS05480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VEA_RS05485	COG0583	DNA-binding transcription factor activity
VEA_RS05495	COG1022	Amp-dependent synthetase and ligase
VEA_RS05500	COG2169	Transcriptional regulator
VEA_RS05525	COG4964	Belongs to the GSP D family
VEA_RS05585	COG0583	DNA-binding transcription factor activity
VEA_RS05590	COG0531	amino acid
VEA_RS05595	COG2731	YhcH YjgK YiaL family protein
VEA_RS05600	COG3250	beta-galactosidase activity
VEA_RS05605	COG1609	Transcriptional regulator
VEA_RS05610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VEA_RS05615	COG1085	galactose-1-phosphate uridylyltransferase
VEA_RS05620	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VEA_RS05625	COG2017	converts alpha-aldose to the beta-anomer
VEA_RS05640	COG2211	Major facilitator Superfamily
VEA_RS05645	COG1609	Transcriptional regulator
VEA_RS05650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VEA_RS05675	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VEA_RS05680	COG1349	DNA-binding transcription factor activity
VEA_RS05685	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VEA_RS05690	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VEA_RS05695	COG2271	Major facilitator Superfamily
VEA_RS05700	COG0584	glycerophosphoryl diester phosphodiesterase
VEA_RS05705	COG2171	N-acyltransferase activity
VEA_RS05710	COG3141	response to X-ray
VEA_RS05730	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VEA_RS05740	COG1074	ATP-dependent DNA helicase activity
VEA_RS05745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VEA_RS05750	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VEA_RS05750	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VEA_RS05760	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VEA_RS05765	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VEA_RS05770	COG2166	iron-sulfur cluster assembly
VEA_RS05775	COG3706	GGDEF domain
VEA_RS05780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VEA_RS05785	COG0693	protein deglycase activity
VEA_RS05790	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VEA_RS05810	COG1595	DNA-templated transcription, initiation
VEA_RS05830	COG3056	Lipoprotein
VEA_RS05835	COG2813	Specifically methylates the guanine in position
VEA_RS05840	COG0271	Belongs to the BolA IbaG family
VEA_RS05850	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VEA_RS05855	COG1805	sodium ion transport
VEA_RS05860	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VEA_RS05865	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VEA_RS05870	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VEA_RS05875	COG2871	sodium ion transport
VEA_RS05880	COG1477	protein flavinylation
VEA_RS05895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VEA_RS05900	COG0514	ATP-dependent DNA helicase (RecQ)
VEA_RS05920	COG0733	neurotransmitter:sodium symporter activity
VEA_RS05940	COG0442	prolyl-tRNA aminoacylation
VEA_RS05945	COG1720	tRNA m6t6A37 methyltransferase activity
VEA_RS05950	COG0254	rRNA binding
VEA_RS05955	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VEA_RS05980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VEA_RS05985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VEA_RS06020	COG0564	pseudouridine synthase activity
VEA_RS06030	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VEA_RS06035	COG0024	Methionine aminopeptidase
VEA_RS06040	COG0052	Belongs to the universal ribosomal protein uS2 family
VEA_RS06045	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VEA_RS06050	COG0528	UMP kinase activity
VEA_RS06055	COG0233	cytoplasmic translational termination
VEA_RS06060	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VEA_RS06065	COG0575	Belongs to the CDS family
VEA_RS06070	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VEA_RS06075	COG0750	zinc metalloprotease
VEA_RS06085	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VEA_RS06090	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VEA_RS06100	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VEA_RS06105	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VEA_RS06115	COG0587	DNA-directed DNA polymerase activity
VEA_RS06120	COG0825	malonyl-CoA metabolic process
VEA_RS06135	COG0347	Belongs to the P(II) protein family
VEA_RS06140	COG3021	interspecies interaction between organisms
VEA_RS06150	COG0741	lytic transglycosylase activity
VEA_RS06150	COG1388	LysM domain
VEA_RS06155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VEA_RS06160	COG2226	methyltransferase
VEA_RS06165	COG0328	RNA-DNA hybrid ribonuclease activity
VEA_RS06200	COG1960	acyl-CoA dehydrogenase activity
VEA_RS06205	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VEA_RS06210	COG0121	glutamine amidotransferase
VEA_RS06215	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VEA_RS06220	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VEA_RS06225	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VEA_RS06230	COG2233	PERMEase
VEA_RS06250	COG1393	Belongs to the ArsC family
VEA_RS06255	COG4783	chaperone-mediated protein folding
VEA_RS06270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VEA_RS06280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VEA_RS06285	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VEA_RS06300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VEA_RS06305	COG1393	Belongs to the ArsC family
VEA_RS06330	COG2837	iron assimilation
VEA_RS06335	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_RS06340	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_RS06345	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_RS06350	COG1334	flagellar protein FlaG
VEA_RS06355	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VEA_RS06365	COG1516	flagellar protein fliS
VEA_RS06385	COG1677	Flagellar hook-basal body complex protein FliE
VEA_RS06395	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VEA_RS06445	COG1987	bacterial-type flagellum assembly
VEA_RS06450	COG1684	flagellar biosynthetic protein fliR
VEA_RS06485	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VEA_RS06490	COG0784	Response regulator, receiver
VEA_RS06490	COG2198	Histidine kinase
VEA_RS06490	COG0643	Histidine kinase
VEA_RS06495	COG2201	protein-glutamate methylesterase activity
VEA_RS06500	COG1192	Involved in chromosome partitioning
VEA_RS06510	COG0835	chemotaxis
VEA_RS06520	COG4133	protoheme IX ABC transporter activity
VEA_RS06525	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VEA_RS06530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VEA_RS06535	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VEA_RS06540	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VEA_RS06545	COG1138	Cytochrome C-type biogenesis protein
VEA_RS06550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VEA_RS06560	COG4235	cytochrome complex assembly
VEA_RS06560	COG3088	subunit of a heme lyase
VEA_RS06570	COG2067	long-chain fatty acid transport protein
VEA_RS06590	COG0183	Belongs to the thiolase family
VEA_RS06595	COG1250	3-hydroxyacyl-CoA dehydrogenase
VEA_RS06595	COG1024	Enoyl-CoA hydratase
VEA_RS06610	COG2062	phosphohistidine phosphatase, SixA
VEA_RS06615	COG2840	Smr protein MutS2
VEA_RS06620	COG2890	protein-(glutamine-N5) methyltransferase activity
VEA_RS06630	COG2860	membrane
VEA_RS06635	COG3101	peptidyl-lysine hydroxylation
VEA_RS06645	COG0431	NADPH-dependent FMN reductase
VEA_RS06650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VEA_RS06650	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VEA_RS06655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VEA_RS06660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VEA_RS06665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VEA_RS06675	COG0101	tRNA pseudouridine synthase activity
VEA_RS06680	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VEA_RS06685	COG0285	dihydrofolate synthase activity
VEA_RS06690	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VEA_RS06695	COG1286	toxin biosynthetic process
VEA_RS06700	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VEA_RS06705	COG0583	DNA-binding transcription factor activity
VEA_RS06710	COG0745	RESPONSE REGULATOR receiver
VEA_RS06720	COG2832	Protein of unknown function (DUF454)
VEA_RS06725	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VEA_RS06740	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VEA_RS06760	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VEA_RS06765	COG0814	amino acid
VEA_RS06770	COG0251	oxidation-reduction process
VEA_RS06775	COG3681	Belongs to the UPF0597 family
VEA_RS06790	COG2261	transglycosylase associated protein
VEA_RS06795	COG2983	Belongs to the UPF0260 family
VEA_RS06800	COG0668	transmembrane transport
VEA_RS06805	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
VEA_RS06810	COG0346	lactoylglutathione lyase activity
VEA_RS06820	COG1785	Belongs to the alkaline phosphatase family
VEA_RS06835	COG2226	methyltransferase
VEA_RS06850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VEA_RS06855	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VEA_RS06865	COG3139	Protein of unknown function (DUF1315)
VEA_RS06870	COG0252	asparaginase activity
VEA_RS06875	COG0616	signal peptide processing
VEA_RS06880	COG0446	pyridine nucleotide-disulphide oxidoreductase
VEA_RS06880	COG1902	pentaerythritol trinitrate reductase activity
VEA_RS06890	COG0778	Nitroreductase
VEA_RS06895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VEA_RS06910	COG0123	including yeast histone deacetylase and acetoin utilization protein
VEA_RS06925	COG3082	Protein of unknown function (DUF1414)
VEA_RS06930	COG3081	Nucleoid-associated protein
VEA_RS06945	COG1757	Na H antiporter
VEA_RS06950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VEA_RS06955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VEA_RS06960	COG2095	MarC family integral membrane protein
VEA_RS06965	COG1454	alcohol dehydrogenase
VEA_RS06965	COG1012	belongs to the aldehyde dehydrogenase family
VEA_RS06985	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VEA_RS06995	COG2056	Na+-H+ antiporter family
VEA_RS07000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VEA_RS07005	COG2885	chlorophyll binding
VEA_RS07015	COG0346	lactoylglutathione lyase activity
VEA_RS07020	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VEA_RS07025	COG4660	Part of a membrane complex involved in electron transport
VEA_RS07030	COG4659	FMN binding
VEA_RS07035	COG4658	electron transport chain
VEA_RS07040	COG4656	Part of a membrane complex involved in electron transport
VEA_RS07045	COG2878	Part of a membrane complex involved in electron transport
VEA_RS07050	COG4657	Part of a membrane complex involved in electron transport
VEA_RS07065	COG0556	nucleotide-excision repair
VEA_RS07070	COG2204	response regulator
VEA_RS07075	COG2198	Histidine kinase
VEA_RS07080	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VEA_RS07085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VEA_RS07090	COG0521	Mo-molybdopterin cofactor biosynthetic process
VEA_RS07095	COG0315	cyclic pyranopterin monophosphate synthase activity
VEA_RS07100	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VEA_RS07105	COG0314	molybdopterin synthase activity
VEA_RS07115	COG0601	transmembrane transport
VEA_RS07120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VEA_RS07125	COG0444	Belongs to the ABC transporter superfamily
VEA_RS07135	COG0435	Glutathione S-transferase
VEA_RS07145	COG3174	membrane
VEA_RS07150	COG0857	belongs to the CobB CobQ family
VEA_RS07150	COG0280	phosphate acetyltransferase
VEA_RS07155	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VEA_RS07160	COG3092	negative regulation of chromosome organization
VEA_RS07170	COG4120	Belongs to the binding-protein-dependent transport system permease family
VEA_RS07175	COG1122	ATPase activity
VEA_RS07180	COG0366	Alpha amylase catalytic
VEA_RS07185	COG3706	GGDEF domain
VEA_RS07190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VEA_RS07195	COG0653	protein targeting
VEA_RS07200	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VEA_RS07205	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VEA_RS07210	COG2186	Transcriptional regulator
VEA_RS07220	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VEA_RS07220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VEA_RS07230	COG0572	uridine kinase
VEA_RS07240	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VEA_RS07245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VEA_RS07250	COG0659	secondary active sulfate transmembrane transporter activity
VEA_RS07255	COG1530	ribonuclease E activity
VEA_RS07260	COG0564	pseudouridine synthase activity
VEA_RS07265	COG0424	maF-like protein
VEA_RS07270	COG1399	metal-binding, possibly nucleic acid-binding protein
VEA_RS07280	COG0416	fatty acid biosynthetic process
VEA_RS07285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VEA_RS07315	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VEA_RS07320	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VEA_RS07325	COG0470	DNA polymerase III
VEA_RS07330	COG0084	hydrolase, TatD family'
VEA_RS07335	COG1263	PTS System
VEA_RS07335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VEA_RS07345	COG0733	neurotransmitter:sodium symporter activity
VEA_RS07360	COG4667	esterase of the alpha-beta hydrolase superfamily
VEA_RS07365	COG0469	pyruvate kinase activity
VEA_RS07370	COG1940	carbohydrate kinase activity
VEA_RS07375	COG0784	Response regulator, receiver
VEA_RS07375	COG0835	chemotaxis
VEA_RS07380	COG0587	DNA-directed DNA polymerase activity
VEA_RS07395	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_RS07400	COG0616	signal peptide processing
VEA_RS07405	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VEA_RS07410	COG0539	negative regulation of cytoplasmic translation
VEA_RS07420	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VEA_RS07425	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VEA_RS07435	COG4166	transmembrane transport
VEA_RS07450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VEA_RS07450	COG3008	intermembrane lipid transfer
VEA_RS07455	COG2995	paraquat-inducible protein a
VEA_RS07460	COG3258	Cytochrome c
VEA_RS07465	COG2863	cytochrome
VEA_RS07500	COG4232	protein-disulfide reductase activity
VEA_RS07505	COG3118	belongs to the thioredoxin family
VEA_RS07535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VEA_RS07545	COG1136	(ABC) transporter
VEA_RS07545	COG0577	efflux transmembrane transporter activity
VEA_RS07550	COG1136	(ABC) transporter
VEA_RS07550	COG0577	efflux transmembrane transporter activity
VEA_RS07555	COG0577	efflux transmembrane transporter activity
VEA_RS07555	COG1136	(ABC) transporter
VEA_RS07610	COG5002	protein histidine kinase activity
VEA_RS07610	COG3850	Histidine kinase
VEA_RS07615	COG0745	RESPONSE REGULATOR receiver
VEA_RS07620	COG0840	transmembrane signaling receptor activity
VEA_RS07635	COG1032	radical SAM domain protein
VEA_RS07640	COG5001	Diguanylate cyclase
VEA_RS07655	COG0583	DNA-binding transcription factor activity
VEA_RS07660	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VEA_RS07670	COG2350	Protein conserved in bacteria
VEA_RS07680	COG2917	probably involved in intracellular septation
VEA_RS07700	COG1301	dicarboxylic acid transport
VEA_RS07710	COG0318	PFAM AMP-dependent synthetase and ligase
VEA_RS07715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VEA_RS07720	COG0159	tryptophan synthase activity
VEA_RS07730	COG0135	phosphoribosylanthranilate isomerase activity
VEA_RS07730	COG0134	indole-3-glycerol-phosphate synthase activity
VEA_RS07740	COG0512	Glutamine amidotransferase of anthranilate synthase
VEA_RS07745	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VEA_RS07755	COG0613	PHP domain protein
VEA_RS07760	COG0009	L-threonylcarbamoyladenylate synthase
VEA_RS07770	COG1187	pseudouridine synthase activity
VEA_RS07790	COG0417	DNA replication proofreading
VEA_RS07795	COG2197	response regulator
VEA_RS07800	COG0322	excinuclease ABC activity
VEA_RS07840	COG0019	diaminopimelate decarboxylase activity
VEA_RS07870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VEA_RS07875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VEA_RS07895	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
VEA_RS07905	COG0437	4 iron, 4 sulfur cluster binding
VEA_RS07910	COG3301	Polysulphide reductase, NrfD
VEA_RS07915	COG1138	Cytochrome C-type biogenesis protein
VEA_RS07925	COG3088	subunit of a heme lyase
VEA_RS07925	COG4235	cytochrome complex assembly
VEA_RS07935	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VEA_RS07960	COG2989	Protein conserved in bacteria
VEA_RS07965	COG3108	Peptidase M15
VEA_RS07970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VEA_RS07985	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VEA_RS08015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VEA_RS08040	COG1448	Aminotransferase
VEA_RS08055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VEA_RS08065	COG0017	Asparaginyl-tRNA synthetase
VEA_RS08070	COG0840	transmembrane signaling receptor activity
VEA_RS08075	COG0720	synthase
VEA_RS08085	COG2200	EAL domain
VEA_RS08090	COG1760	l-serine dehydratase
VEA_RS08095	COG0814	amino acid
VEA_RS08100	COG0494	nUDIX hydrolase
VEA_RS08110	COG0784	Response regulator, receiver
VEA_RS08110	COG2205	protein histidine kinase activity
VEA_RS08115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VEA_RS08130	COG3106	COG3106 Predicted ATPase
VEA_RS08135	COG3768	UPF0283 membrane protein
VEA_RS08145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VEA_RS08245	COG0346	lactoylglutathione lyase activity
VEA_RS08265	COG0346	lactoylglutathione lyase activity
VEA_RS08310	COG0346	lactoylglutathione lyase activity
VEA_RS08395	COG4735	regulation of single-species biofilm formation
VEA_RS08410	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VEA_RS08410	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VEA_RS08480	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VEA_RS08520	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VEA_RS08570	COG0582	viral genome integration into host DNA
VEA_RS08710	COG0582	viral genome integration into host DNA
VEA_RS08740	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VEA_RS08745	COG0210	DNA helicase
VEA_RS08760	COG0456	acetyltransferase
VEA_RS08780	COG0625	glutathione transferase activity
VEA_RS08835	COG5507	3-demethylubiquinone-9 3-methyltransferase
VEA_RS08840	COG1280	lysine exporter protein (LysE YggA)
VEA_RS08870	COG0583	DNA-binding transcription factor activity
VEA_RS08880	COG1566	PFAM secretion protein HlyD family protein
VEA_RS08895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VEA_RS08910	COG3290	protein histidine kinase activity
VEA_RS08915	COG4565	transcriptional regulatory protein
VEA_RS08930	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VEA_RS08935	COG0363	glucosamine-6-phosphate deaminase activity
VEA_RS08940	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VEA_RS08960	COG3284	Transcriptional regulator
VEA_RS08965	COG1012	belongs to the aldehyde dehydrogenase family
VEA_RS09035	COG4669	(LipO)protein
VEA_RS09055	COG3177	Filamentation induced by cAMP protein fic
VEA_RS09085	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_RS09120	COG4792	protein secretion
VEA_RS09125	COG4791	protein targeting
VEA_RS09130	COG4794	Type iii secretion
VEA_RS09135	COG4790	Type iii secretion
VEA_RS09205	COG0457	Tetratricopeptide repeat
VEA_RS09225	COG2358	TRAP transporter, solute receptor (TAXI family
VEA_RS09230	COG0730	response to heat
VEA_RS09265	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VEA_RS09270	COG0372	Belongs to the citrate synthase family
VEA_RS09280	COG2828	Protein conserved in bacteria
VEA_RS09305	COG0561	phosphatase activity
VEA_RS09310	COG0602	queuosine metabolic process
VEA_RS09315	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VEA_RS09320	COG3706	GGDEF domain
VEA_RS09370	COG1254	Belongs to the acylphosphatase family
VEA_RS09375	COG2920	part of a sulfur-relay system
VEA_RS09385	COG0670	Belongs to the BI1 family
VEA_RS09390	COG1126	abc transporter atp-binding protein
VEA_RS09395	COG0765	amino acid transport
VEA_RS09400	COG4597	amino acid ABC transporter
VEA_RS09405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VEA_RS09415	COG1666	GTP binding
VEA_RS09420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VEA_RS09445	COG3008	intermembrane lipid transfer
VEA_RS09450	COG2995	paraquat-inducible protein a
VEA_RS09455	COG1132	(ABC) transporter
VEA_RS09460	COG1956	GAF domain-containing protein
VEA_RS09465	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VEA_RS09480	COG0308	aminopeptidase N
VEA_RS09485	COG2902	Dehydrogenase
VEA_RS09490	COG0167	dihydroorotate dehydrogenase activity
VEA_RS09500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VEA_RS09500	COG0116	Belongs to the methyltransferase superfamily
VEA_RS09510	COG0488	(ABC) transporter
VEA_RS09525	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VEA_RS09530	COG1067	ATP-dependent peptidase activity
VEA_RS09535	COG3120	sequence-specific DNA binding
VEA_RS09610	COG2205	protein histidine kinase activity
VEA_RS09610	COG0784	Response regulator, receiver
VEA_RS09625	COG3278	Belongs to the heme-copper respiratory oxidase family
VEA_RS09640	COG2010	Cytochrome c
VEA_RS09650	COG2217	Heavy metal translocating P-type atpase
VEA_RS09665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VEA_RS09670	COG0589	response to stress
VEA_RS09695	COG3842	ATPase activity
VEA_RS09705	COG1177	transmembrane transport
VEA_RS09715	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VEA_RS09720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VEA_RS09725	COG0004	ammonium transporteR
VEA_RS09750	COG0437	4 iron, 4 sulfur cluster binding
VEA_RS09755	COG3383	formate dehydrogenase (NAD+) activity
VEA_RS09755	COG0243	molybdopterin cofactor binding
VEA_RS09765	COG3381	protein complex oligomerization
VEA_RS09785	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VEA_RS09795	COG0488	(ABC) transporter
VEA_RS09800	COG4191	Histidine kinase
VEA_RS09805	COG2204	response regulator
VEA_RS09820	COG3842	ATPase activity
VEA_RS09825	COG0746	molybdenum cofactor guanylyltransferase activity
VEA_RS09830	COG0303	'Molybdopterin
VEA_RS09840	COG1940	carbohydrate kinase activity
VEA_RS09845	COG3148	PFAM DTW domain containing protein
VEA_RS09875	COG0840	transmembrane signaling receptor activity
VEA_RS09880	COG0791	NLP P60 protein
VEA_RS09890	COG3706	GGDEF domain
VEA_RS09900	COG3001	Fructosamine kinase
VEA_RS09910	COG0307	riboflavin synthase, alpha
VEA_RS09915	COG0534	Mate efflux family protein
VEA_RS09925	COG1793	dna ligase
VEA_RS09955	COG2204	response regulator
VEA_RS09965	COG0438	transferase activity, transferring glycosyl groups
VEA_RS09995	COG0438	transferase activity, transferring glycosyl groups
VEA_RS10000	COG1215	transferase activity, transferring glycosyl groups
VEA_RS10005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VEA_RS10015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VEA_RS10030	COG1643	Atp-dependent helicase
VEA_RS10035	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
VEA_RS10080	COG0443	Heat shock 70 kDa protein
VEA_RS10085	COG0443	Heat shock 70 kDa protein
VEA_RS10105	COG2165	general secretion pathway protein
VEA_RS10110	COG1132	(ABC) transporter
VEA_RS10115	COG1132	(ABC) transporter
VEA_RS10125	COG4774	siderophore transport
VEA_RS10135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VEA_RS10140	COG1120	ATPase activity
VEA_RS10155	COG0814	amino acid
VEA_RS10165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VEA_RS10175	COG0861	Integral membrane protein TerC family
VEA_RS10185	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VEA_RS10190	COG1328	CTP reductase activity
VEA_RS10205	COG3300	MHYT domain
VEA_RS10205	COG5001	Diguanylate cyclase
VEA_RS10215	COG4191	Histidine kinase
VEA_RS10220	COG0471	metal ion transport
VEA_RS10245	COG4702	Belongs to the UPF0303 family
VEA_RS10250	COG0673	inositol 2-dehydrogenase activity
VEA_RS10255	COG1349	DNA-binding transcription factor activity
VEA_RS10270	COG0641	radical SAM
VEA_RS10285	COG3119	arylsulfatase activity
VEA_RS10290	COG0527	aspartate kinase activity
VEA_RS10295	COG0662	Cupin 2, conserved barrel domain protein
VEA_RS10300	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VEA_RS10305	COG0456	acetyltransferase
VEA_RS10310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VEA_RS10330	COG4176	ABC-type proline glycine betaine transport system permease component
VEA_RS10335	COG2113	Glycine betaine
VEA_RS10345	COG1022	Amp-dependent synthetase and ligase
VEA_RS10355	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_RS10365	COG0745	RESPONSE REGULATOR receiver
VEA_RS10370	COG0642	Histidine kinase
VEA_RS10375	COG1368	sulfuric ester hydrolase activity
VEA_RS10405	COG1115	amino acid carrier protein
VEA_RS10415	COG1280	lysine exporter protein (LysE YggA)
VEA_RS10420	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VEA_RS10425	COG1560	Kdo2-lipid A biosynthetic process
VEA_RS10435	COG0531	amino acid
VEA_RS10450	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VEA_RS10455	COG3063	Type IV pilus biogenesis stability protein PilW
VEA_RS10485	COG0110	maltose O-acetyltransferase activity
VEA_RS10500	COG2315	Protein conserved in bacteria
VEA_RS10505	COG1846	Transcriptional regulator
VEA_RS10515	COG2200	EAL domain
VEA_RS10550	COG0625	glutathione transferase activity
VEA_RS10560	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VEA_RS10570	COG2195	Cleaves the N-terminal amino acid of tripeptides
VEA_RS10580	COG0601	transmembrane transport
VEA_RS10585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VEA_RS10605	COG3291	Pkd domain containing protein
VEA_RS10620	COG1177	transmembrane transport
VEA_RS10625	COG1176	ABC-type spermidine putrescine transport system, permease component I
VEA_RS10630	COG3842	ATPase activity
VEA_RS10635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VEA_RS10640	COG2423	ornithine cyclodeaminase activity
VEA_RS10655	COG3938	Belongs to the proline racemase family
VEA_RS10685	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
VEA_RS10690	COG1451	nucleotide metabolic process
VEA_RS10700	COG0583	DNA-binding transcription factor activity
VEA_RS10720	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VEA_RS10725	COG4139	cobalamin transport
VEA_RS10730	COG2988	succinylglutamate desuccinylase activity
VEA_RS10750	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VEA_RS10755	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VEA_RS10760	COG0702	epimerase
VEA_RS10765	COG1823	symporter activity
VEA_RS10770	COG2925	Exonuclease
VEA_RS10775	COG1380	Effector of murein hydrolase LrgA
VEA_RS10780	COG1346	cytolysis
VEA_RS10785	COG0295	cytidine deaminase activity
VEA_RS10790	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
VEA_RS10795	COG0500	methyltransferase
VEA_RS10805	COG0776	regulation of translation
VEA_RS10815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VEA_RS10815	COG0072	phenylalanine-tRNA ligase activity
VEA_RS10820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VEA_RS10850	COG0393	Putative heavy-metal-binding
VEA_RS10860	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VEA_RS10870	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
VEA_RS10885	COG2188	Transcriptional regulator
VEA_RS10890	COG1228	amidohydrolase
VEA_RS10895	COG0010	Belongs to the arginase family
VEA_RS10900	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VEA_RS10905	COG2986	histidine ammonia-lyase
VEA_RS10920	COG0277	FAD linked oxidase domain protein
VEA_RS10920	COG0247	lactate metabolic process
VEA_RS10950	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VEA_RS10965	COG1643	Atp-dependent helicase
VEA_RS10970	COG0281	malic enzyme
VEA_RS10975	COG2949	membrane
VEA_RS10980	COG0471	metal ion transport
VEA_RS11005	COG0492	ferredoxin-NADP+ reductase activity
VEA_RS11010	COG4988	ABC transporter
VEA_RS11015	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VEA_RS11025	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VEA_RS11035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VEA_RS11035	COG4191	Histidine kinase
VEA_RS11050	COG3070	regulator of competence-specific genes
VEA_RS11060	COG2431	L-lysine efflux transmembrane transporter activity
VEA_RS11070	COG0076	glutamate decarboxylase activity
VEA_RS11075	COG1737	Transcriptional regulator
VEA_RS11085	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VEA_RS11090	COG2985	domain, Protein
VEA_RS11090	COG3273	potassium ion transport
VEA_RS11095	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VEA_RS11100	COG1960	acyl-CoA dehydrogenase activity
VEA_RS11115	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VEA_RS11135	COG0534	Mate efflux family protein
VEA_RS11140	COG0702	epimerase
VEA_RS11145	COG3005	denitrification pathway
VEA_RS11175	COG2814	Major facilitator Superfamily
VEA_RS11180	COG1187	pseudouridine synthase activity
VEA_RS11185	COG1061	Type III restriction enzyme res subunit
VEA_RS11205	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VEA_RS11225	COG3313	Fe-S protein
VEA_RS11235	COG4134	Bacterial extracellular solute-binding protein
VEA_RS11240	COG4135	transport system, permease component
VEA_RS11245	COG4136	ATPase activity
VEA_RS11250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VEA_RS11260	COG3604	Transcriptional regulator
VEA_RS11265	COG1151	hydroxylamine reductase activity
VEA_RS11270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VEA_RS11280	COG0564	pseudouridine synthase activity
VEA_RS11285	COG0733	neurotransmitter:sodium symporter activity
VEA_RS11295	COG0626	cystathionine gamma-synthase activity
VEA_RS11300	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VEA_RS11305	COG5380	lipid catabolic process
VEA_RS11310	COG2818	Glycosylase
VEA_RS11330	COG1983	PspC domain protein
VEA_RS11340	COG1842	Phage shock protein A
VEA_RS11345	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VEA_RS11360	COG4171	peptide transport system, permease
VEA_RS11370	COG4172	Belongs to the ABC transporter superfamily
VEA_RS11380	COG1227	inorganic diphosphatase activity
VEA_RS11395	COG0243	molybdopterin cofactor binding
VEA_RS11400	COG3005	denitrification pathway
VEA_RS11405	COG4459	periplasmic nitrate reductase
VEA_RS11410	COG0390	transport system, permease component
VEA_RS11415	COG2116	formate transmembrane transporter activity
VEA_RS11440	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VEA_RS11445	COG1435	thymidine kinase activity
VEA_RS11450	COG0215	cysteine-tRNA ligase activity
VEA_RS11455	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VEA_RS11460	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VEA_RS11465	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VEA_RS11470	COG3012	SEC-C Motif Domain Protein
VEA_RS11475	COG0140	phosphoribosyl-ATP diphosphatase activity
VEA_RS11475	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VEA_RS11485	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VEA_RS11490	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VEA_RS11495	COG0131	Imidazoleglycerol-phosphate dehydratase
VEA_RS11495	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VEA_RS11500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VEA_RS11505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VEA_RS11510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VEA_RS11520	COG1757	Na H antiporter
VEA_RS11530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VEA_RS11540	COG0482	sulfurtransferase activity
VEA_RS11545	COG2915	High frequency lysogenization protein hflD homolog
VEA_RS11550	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VEA_RS11560	COG2268	Band 7 protein
VEA_RS11570	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VEA_RS11585	COG0300	oxidoreductase activity
VEA_RS11600	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VEA_RS11605	COG1073	alpha beta
VEA_RS11605	COG2226	methyltransferase
VEA_RS11635	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VEA_RS11640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VEA_RS11645	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VEA_RS11650	COG1674	ftsk spoiiie
VEA_RS11660	COG0686	Belongs to the AlaDH PNT family
VEA_RS11670	COG0583	DNA-binding transcription factor activity
VEA_RS11685	COG0840	transmembrane signaling receptor activity
VEA_RS11695	COG3568	Endonuclease Exonuclease Phosphatase
VEA_RS11720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VEA_RS11725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VEA_RS11730	COG0840	transmembrane signaling receptor activity
VEA_RS11745	COG0328	RNA-DNA hybrid ribonuclease activity
VEA_RS11775	COG5002	protein histidine kinase activity
VEA_RS11775	COG0784	Response regulator, receiver
VEA_RS11785	COG0754	glutathionylspermidine amidase activity
VEA_RS11795	COG3766	membrane
VEA_RS11805	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VEA_RS11810	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
VEA_RS11815	COG2885	chlorophyll binding
VEA_RS11820	COG0823	Involved in the tonB-independent uptake of proteins
VEA_RS11835	COG0811	peptide transport
VEA_RS11840	COG0824	Thioesterase
VEA_RS11855	COG1294	oxidase, subunit
VEA_RS11860	COG1271	oxidase subunit
VEA_RS11865	COG2255	four-way junction helicase activity
VEA_RS11870	COG0632	four-way junction helicase activity
VEA_RS11875	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VEA_RS11880	COG0217	transcriptional regulatory protein
VEA_RS11890	COG1801	Protein of unknown function DUF72
VEA_RS11900	COG0500	methyltransferase
VEA_RS11905	COG4067	protein conserved in archaea
VEA_RS11905	COG0189	ligase activity
VEA_RS11920	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
VEA_RS11925	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VEA_RS11930	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VEA_RS11935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VEA_RS11940	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VEA_RS11945	COG0745	RESPONSE REGULATOR receiver
VEA_RS11950	COG3381	protein complex oligomerization
VEA_RS11955	COG1609	Transcriptional regulator
VEA_RS11960	COG3070	regulator of competence-specific genes
VEA_RS11980	COG0297	glycogen (starch) synthase activity
VEA_RS11985	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VEA_RS11990	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VEA_RS12010	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VEA_RS12015	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
VEA_RS12020	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VEA_RS12025	COG0542	response to heat
VEA_RS12030	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VEA_RS12035	COG1278	Cold shock
VEA_RS12045	COG1187	pseudouridine synthase activity
VEA_RS12050	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VEA_RS12055	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VEA_RS12060	COG1199	ATP-dependent helicase activity
VEA_RS12065	COG0730	response to heat
VEA_RS12070	COG3923	Primosomal replication protein n
VEA_RS12080	COG0708	Exodeoxyribonuclease III
VEA_RS12120	COG1882	Formate acetyltransferase
VEA_RS12130	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VEA_RS12140	COG3013	Belongs to the UPF0304 family
VEA_RS12145	COG2766	serine protein kinase
VEA_RS12150	COG2718	Belongs to the UPF0229 family
VEA_RS12155	COG2719	SpoVR family
VEA_RS12175	COG1132	(ABC) transporter
VEA_RS12180	COG2333	competence protein COMEC
VEA_RS12180	COG0658	competence protein
VEA_RS12190	COG4591	ABC-type transport system involved in lipoprotein release permease component
VEA_RS12195	COG1136	(ABC) transporter
VEA_RS12200	COG4591	ABC-type transport system involved in lipoprotein release permease component
VEA_RS12210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VEA_RS12225	COG1252	NADH dehydrogenase
VEA_RS12230	COG3150	esterase
VEA_RS12255	COG0537	adenosine 5'-monophosphoramidase activity
VEA_RS12280	COG0516	GMP reductase activity
VEA_RS12280	COG0517	IMP dehydrogenase activity
VEA_RS12285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VEA_RS12305	COG3126	Type III secretion system lipoprotein chaperone (YscW)
VEA_RS12310	COG1946	Acyl-CoA thioesterase
VEA_RS12320	COG1522	sequence-specific DNA binding
VEA_RS12345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VEA_RS12350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VEA_RS12380	COG0477	Major facilitator Superfamily
VEA_RS12385	COG2855	membrane
VEA_RS12405	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
VEA_RS12410	COG0596	Alpha beta hydrolase
VEA_RS12415	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VEA_RS12420	COG1169	isochorismate synthase
VEA_RS12425	COG0436	Aminotransferase
VEA_RS12430	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VEA_RS12435	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VEA_RS12450	COG1555	photosystem II stabilization
VEA_RS12455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VEA_RS12460	COG0776	regulation of translation
VEA_RS12465	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VEA_RS12470	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VEA_RS12480	COG0544	peptidyl-prolyl cis-trans isomerase activity
VEA_RS12500	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VEA_RS12505	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VEA_RS12510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VEA_RS12515	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VEA_RS12530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VEA_RS12535	COG0569	domain protein
VEA_RS12540	COG0513	Belongs to the DEAD box helicase family
VEA_RS12545	COG1253	flavin adenine dinucleotide binding
VEA_RS12580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VEA_RS12585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VEA_RS12600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VEA_RS12605	COG1216	Glycosyl transferase, family 2
VEA_RS12610	COG2986	histidine ammonia-lyase
VEA_RS12635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VEA_RS12645	COG1028	Short-chain dehydrogenase reductase Sdr
VEA_RS12650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VEA_RS12655	COG2226	methyltransferase
VEA_RS12665	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VEA_RS12670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VEA_RS12680	COG2951	lytic endotransglycosylase activity
VEA_RS12685	COG3100	YcgL domain-containing protein
VEA_RS12690	COG0850	regulation of cytokinetic process
VEA_RS12695	COG2894	cell division
VEA_RS12700	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VEA_RS12705	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VEA_RS12710	COG0318	PFAM AMP-dependent synthetase and ligase
VEA_RS12715	COG2267	carboxylic ester hydrolase activity
VEA_RS12720	COG3065	identical protein binding
VEA_RS12730	COG1214	PFAM Peptidase M22, glycoprotease
VEA_RS12735	COG1199	ATP-dependent helicase activity
VEA_RS12740	COG0788	formyltetrahydrofolate deformylase activity
VEA_RS12755	COG3102	Protein conserved in bacteria
VEA_RS12760	COG0018	arginyl-trna synthetase
VEA_RS12780	COG1918	ferrous iron import across plasma membrane
VEA_RS12785	COG4977	sequence-specific DNA binding
VEA_RS12790	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VEA_RS12795	COG1121	(ABC) transporter
VEA_RS12800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VEA_RS12815	COG0508	dehydrogenase complex catalyzes the overall conversion of
VEA_RS12820	COG0567	Dehydrogenase, E1 component
VEA_RS12825	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VEA_RS12830	COG1053	succinate dehydrogenase
VEA_RS12835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VEA_RS12850	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VEA_RS12860	COG0033	Phosphoglucomutase
VEA_RS12865	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VEA_RS12870	COG0596	Alpha beta hydrolase
VEA_RS12880	COG0716	FMN binding
VEA_RS12890	COG0735	belongs to the Fur family
VEA_RS12895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VEA_RS12900	COG2190	(PTS) system
VEA_RS12900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VEA_RS12900	COG1263	PTS System
VEA_RS12905	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VEA_RS12910	COG1846	Transcriptional regulator
VEA_RS12910	COG1940	carbohydrate kinase activity
VEA_RS12915	COG4651	solute:proton antiporter activity
VEA_RS12915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VEA_RS12920	COG0367	asparagine synthase
VEA_RS12925	COG0250	Participates in transcription elongation, termination and antitermination
VEA_RS12930	COG3104	oligopeptide transport
VEA_RS12935	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VEA_RS12945	COG0326	Molecular chaperone. Has ATPase activity
VEA_RS12950	COG3710	Transcriptional regulator
VEA_RS12970	COG0622	Phosphoesterase
VEA_RS12995	COG1090	epimerase
VEA_RS13000	COG0300	oxidoreductase activity
VEA_RS13005	COG3118	belongs to the thioredoxin family
VEA_RS13010	COG0330	HflC and HflK could
VEA_RS13025	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VEA_RS13030	COG3115	cell septum assembly
VEA_RS13035	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VEA_RS13040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VEA_RS13045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VEA_RS13050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VEA_RS13055	COG2190	(PTS) system
VEA_RS13060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_RS13065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_RS13070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_RS13075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VEA_RS13085	COG1705	Flagellar rod assembly protein muramidase FlgJ
VEA_RS13085	COG3951	Flagellar rod assembly protein muramidase FlgJ
VEA_RS13090	COG1706	bacterial-type flagellum-dependent cell motility
VEA_RS13095	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VEA_RS13105	COG4787	bacterial-type flagellum-dependent cell motility
VEA_RS13110	COG1749	Flagellar hook protein flgE
VEA_RS13120	COG1558	bacterial-type flagellum-dependent cell motility
VEA_RS13125	COG1815	bacterial-type flagellum-dependent cell motility
VEA_RS13130	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VEA_RS13135	COG0835	chemotaxis
VEA_RS13135	COG0784	Response regulator, receiver
VEA_RS13190	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VEA_RS13200	COG2608	mercury ion transmembrane transporter activity
VEA_RS13200	COG2217	Heavy metal translocating P-type atpase
VEA_RS13240	COG2840	Smr protein MutS2
VEA_RS13245	COG1187	pseudouridine synthase activity
VEA_RS13255	COG0737	Belongs to the 5'-nucleotidase family
VEA_RS13260	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VEA_RS13265	COG2912	Transglutaminase-like superfamily
VEA_RS13270	COG3094	Invasion gene expression up-regulator, SirB
VEA_RS13275	COG2890	protein-(glutamine-N5) methyltransferase activity
VEA_RS13280	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VEA_RS13285	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VEA_RS13290	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VEA_RS13300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VEA_RS13305	COG0193	aminoacyl-tRNA hydrolase activity
VEA_RS13310	COG0012	GTP binding
VEA_RS13415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VEA_RS13420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VEA_RS13425	COG1702	phosphate starvation-inducible protein PhoH
VEA_RS13430	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VEA_RS13435	COG4535	Mg2 and Co2 transporter CorC
VEA_RS13440	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VEA_RS13445	COG2888	peptidyl-tyrosine sulfation
VEA_RS13450	COG0495	leucyl-tRNA aminoacylation
VEA_RS13455	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VEA_RS13460	COG1466	dna polymerase III delta subunit
VEA_RS13465	COG0799	negative regulation of ribosome biogenesis
VEA_RS13470	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VEA_RS13475	COG0768	penicillin binding
VEA_RS13480	COG0772	Belongs to the SEDS family
VEA_RS13485	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VEA_RS13490	COG1686	Belongs to the peptidase S11 family
VEA_RS13500	COG0321	lipoyl(octanoyl) transferase activity
VEA_RS13505	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VEA_RS13510	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VEA_RS13515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
VEA_RS13530	COG0366	Alpha amylase catalytic
VEA_RS13535	COG1263	PTS System
VEA_RS13535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VEA_RS13545	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VEA_RS13550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VEA_RS13555	COG2011	ABC-type metal ion transport system permease component
VEA_RS13560	COG1464	Belongs to the NlpA lipoprotein family
VEA_RS13565	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VEA_RS13575	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VEA_RS13575	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VEA_RS13590	COG1611	Belongs to the LOG family
VEA_RS13595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VEA_RS13605	COG2363	Small membrane protein
VEA_RS13615	COG0583	DNA-binding transcription factor activity
VEA_RS13620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VEA_RS13620	COG0301	tRNA thio-modification
VEA_RS13630	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VEA_RS13635	COG1722	exodeoxyribonuclease VII activity
VEA_RS13640	COG0142	geranyltranstransferase activity
VEA_RS13645	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VEA_RS13650	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VEA_RS13655	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VEA_RS13665	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VEA_RS13680	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VEA_RS13680	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VEA_RS13685	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VEA_RS13690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VEA_RS13695	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VEA_RS13705	COG1073	alpha beta
VEA_RS13710	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VEA_RS13715	COG2252	PERMEase
VEA_RS13720	COG2195	Cleaves the N-terminal amino acid of tripeptides
VEA_RS13735	COG1629	transport
VEA_RS13750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VEA_RS13750	COG0047	phosphoribosylformylglycinamidine synthase activity
VEA_RS13755	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VEA_RS13765	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VEA_RS13795	COG0484	heat shock protein binding
VEA_RS13805	COG1301	dicarboxylic acid transport
VEA_RS13810	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VEA_RS13815	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VEA_RS13825	COG0497	DNA recombination
VEA_RS13830	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VEA_RS13835	COG2914	Belongs to the UPF0125 (RnfH) family
VEA_RS13840	COG2867	negative regulation of translational initiation
VEA_RS13845	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VEA_RS13850	COG0582	viral genome integration into host DNA
VEA_RS13880	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VEA_RS13905	COG3311	Transcriptional regulator
VEA_RS13930	COG0583	DNA-binding transcription factor activity
VEA_RS13935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VEA_RS13935	COG3153	acetyltransferase
VEA_RS13955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VEA_RS13960	COG2873	o-acetylhomoserine
VEA_RS13980	COG1115	amino acid carrier protein
VEA_RS13985	COG1584	GPR1 FUN34 yaaH family protein
VEA_RS13995	COG1757	Na H antiporter
VEA_RS14035	COG0582	viral genome integration into host DNA
VEA_RS14040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VEA_RS14040	COG0519	Catalyzes the synthesis of GMP from XMP
VEA_RS14045	COG0517	IMP dehydrogenase activity
VEA_RS14045	COG0516	GMP reductase activity
VEA_RS14065	COG1160	GTP binding
VEA_RS14070	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VEA_RS14075	COG2976	Protein conserved in bacteria
VEA_RS14080	COG0124	histidyl-tRNA synthetase
VEA_RS14085	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VEA_RS14100	COG0105	UTP biosynthetic process
VEA_RS14110	COG2975	iron-sulfur cluster assembly
VEA_RS14115	COG0633	Ferredoxin
VEA_RS14120	COG0443	Heat shock 70 kDa protein
VEA_RS14135	COG0822	iron-sulfur transferase activity
VEA_RS14140	COG1104	cysteine desulfurase activity
VEA_RS14150	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
VEA_RS14155	COG0483	inositol monophosphate 1-phosphatase activity
VEA_RS14160	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VEA_RS14165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VEA_RS14170	COG1862	Preprotein translocase
VEA_RS14180	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VEA_RS14190	COG0517	IMP dehydrogenase activity
VEA_RS14200	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VEA_RS14205	COG0583	DNA-binding transcription factor activity
VEA_RS14210	COG0450	alkyl hydroperoxide reductase
VEA_RS14215	COG3142	Participates in the control of copper homeostasis
VEA_RS14225	COG0704	Plays a role in the regulation of phosphate uptake
VEA_RS14230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VEA_RS14235	COG0581	inorganic phosphate transmembrane transporter activity
VEA_RS14240	COG0573	inorganic phosphate transmembrane transporter activity
VEA_RS14245	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VEA_RS14250	COG0248	Ppx GppA phosphatase
VEA_RS14260	COG5002	protein histidine kinase activity
VEA_RS14265	COG0745	RESPONSE REGULATOR receiver
VEA_RS14270	COG2974	May be involved in recombination
VEA_RS14275	COG0826	peptidase U32
VEA_RS14280	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VEA_RS14335	COG0542	response to heat
VEA_RS14345	COG0564	pseudouridine synthase activity
VEA_RS14350	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VEA_RS14355	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VEA_RS14360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VEA_RS14365	COG0077	Prephenate dehydratase
VEA_RS14365	COG1605	Chorismate mutase
VEA_RS14370	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
VEA_RS14375	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VEA_RS14385	COG0488	(ABC) transporter
VEA_RS14395	COG0739	heme binding
VEA_RS14395	COG1196	nuclear chromosome segregation
VEA_RS14395	COG0741	lytic transglycosylase activity
VEA_RS14400	COG0287	Prephenate dehydrogenase
VEA_RS14400	COG1605	Chorismate mutase
VEA_RS14405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VEA_RS14410	COG1472	Belongs to the glycosyl hydrolase 3 family
VEA_RS14415	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VEA_RS14435	COG1966	Carbon starvation protein
VEA_RS14440	COG3275	phosphorelay sensor kinase activity
VEA_RS14445	COG3279	Response regulator of the LytR AlgR family
VEA_RS14455	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VEA_RS14460	COG1047	Peptidyl-prolyl cis-trans
VEA_RS14465	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VEA_RS14475	COG0196	riboflavin kinase activity
VEA_RS14480	COG0728	peptidoglycan biosynthetic process
VEA_RS14485	COG0268	Binds directly to 16S ribosomal RNA
VEA_RS14490	COG0640	Transcriptional regulator
VEA_RS14495	COG0583	DNA-binding transcription factor activity
VEA_RS14500	COG1283	sodium-dependent phosphate transmembrane transporter activity
VEA_RS14510	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
VEA_RS14515	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VEA_RS14520	COG0730	response to heat
VEA_RS14545	COG0667	Aldo Keto reductase
VEA_RS14555	COG2204	response regulator
VEA_RS14560	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VEA_RS14565	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VEA_RS14570	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VEA_RS14575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VEA_RS14580	COG4974	Belongs to the 'phage' integrase family
VEA_RS14585	COG0716	FMN binding
VEA_RS14595	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
VEA_RS14600	COG0513	Belongs to the DEAD box helicase family
VEA_RS14605	COG3022	response to hydroperoxide
VEA_RS14610	COG1115	amino acid carrier protein
VEA_RS14625	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VEA_RS14630	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VEA_RS14635	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VEA_RS14645	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VEA_RS14650	COG0083	homoserine kinase activity
VEA_RS14665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VEA_RS14675	COG0745	RESPONSE REGULATOR receiver
VEA_RS14685	COG2198	Histidine kinase
VEA_RS14685	COG0784	Response regulator, receiver
VEA_RS14685	COG5002	protein histidine kinase activity
VEA_RS14690	COG3706	GGDEF domain
VEA_RS14690	COG4251	negative regulation of phosphorylation
VEA_RS14690	COG5001	Diguanylate cyclase
VEA_RS14690	COG2203	Gaf domain
VEA_RS14695	COG1242	4 iron, 4 sulfur cluster binding
VEA_RS14700	COG0070	glutamate synthase
VEA_RS14700	COG0069	glutamate synthase activity
VEA_RS14700	COG0067	glutamate synthase
VEA_RS14710	COG0069	glutamate synthase activity
VEA_RS14710	COG0067	glutamate synthase
VEA_RS14710	COG0070	glutamate synthase
VEA_RS14715	COG0493	'glutamate synthase
VEA_RS14725	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VEA_RS14740	COG2860	membrane
VEA_RS14745	COG0583	DNA-binding transcription factor activity
VEA_RS14750	COG0730	response to heat
VEA_RS14765	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VEA_RS14770	COG0505	Belongs to the CarA family
VEA_RS14785	COG0494	nUDIX hydrolase
VEA_RS14790	COG0653	protein targeting
VEA_RS14800	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VEA_RS14805	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VEA_RS14810	COG0849	cell division
VEA_RS14815	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VEA_RS14820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VEA_RS14830	COG0772	Belongs to the SEDS family
VEA_RS14835	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VEA_RS14840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VEA_RS14845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VEA_RS14850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VEA_RS14855	COG0768	penicillin binding
VEA_RS14860	COG3116	cell division
VEA_RS14875	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VEA_RS14890	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VEA_RS14895	COG2823	Periplasmic or secreted lipoprotein
VEA_RS14900	COG2969	positive regulation of protein catabolic process
VEA_RS14905	COG0625	glutathione transferase activity
VEA_RS14910	COG2857	Cytochrome c1
VEA_RS14915	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VEA_RS14920	COG0723	plastoquinol--plastocyanin reductase activity
VEA_RS14925	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VEA_RS14930	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VEA_RS14935	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VEA_RS14940	COG3105	Protein conserved in bacteria
VEA_RS14950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VEA_RS14955	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VEA_RS14965	COG3150	esterase
VEA_RS14975	COG3151	Protein conserved in bacteria
VEA_RS14980	COG0494	nUDIX hydrolase
VEA_RS14985	COG1538	Outer membrane efflux protein
VEA_RS14990	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
VEA_RS14990	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
VEA_RS14995	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VEA_RS15010	COG3025	triphosphatase activity
VEA_RS15015	COG1392	Phosphate transport regulator
VEA_RS15020	COG0306	phosphate transporter
VEA_RS15100	COG0358	DNA primase activity
VEA_RS15280	COG0473	3-isopropylmalate dehydrogenase activity
VEA_RS15325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VEA_RS15445	COG2105	PFAM AIG2 family protein
VEA_RS15520	COG0175	sulfate reduction
VEA_RS15625	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VEA_RS15810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VEA_RS15975	COG3642	lipopolysaccharide core region biosynthetic process
VEA_RS16250	COG2183	response to ionizing radiation
VEA_RS16305	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VEA_RS16325	COG1459	type II secretion system
VEA_RS16345	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VEA_RS16830	COG0751	glycine-tRNA ligase activity
VEA_RS16980	COG2814	Major facilitator Superfamily
VEA_RS17260	COG0248	Ppx GppA phosphatase
VEA_RS17525	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VEA_RS17585	COG0531	amino acid
VEA_RS17830	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VEA_RS17920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VEA_RS17960	COG4942	peptidase
VEA_RS17965	COG1045	serine acetyltransferase
VEA_RS18175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VEA_RS18175	COG0475	glutathione-regulated potassium exporter activity
VEA_RS18190	COG1446	asparaginase
VEA_RS18250	COG0626	cystathionine gamma-synthase activity
VEA_RS18930	COG0726	polysaccharide deacetylase
VEA_RS19235	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VEA_RS19325	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VEA_RS19340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VEA_RS19440	COG2918	glutathione biosynthetic process
VEA_RS19610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VEA_RS19870	COG2027	D-alanyl-D-alanine carboxypeptidase
VEA_RS19925	COG0195	Participates in both transcription termination and antitermination
VEA_RS19955	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
VEA_RS20190	COG3250	beta-galactosidase activity
VEA_RS20300	COG2271	Major facilitator Superfamily
VEA_RS20695	COG1960	acyl-CoA dehydrogenase activity
VEA_RS21095	COG0183	Belongs to the thiolase family
VEA_RS21280	COG3681	Belongs to the UPF0597 family
VEA_RS21330	COG0676	glucose-6-phosphate 1-epimerase activity
VEA_RS21430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VEA_RS21680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VEA_RS21680	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VEA_RS21725	COG0659	secondary active sulfate transmembrane transporter activity
VEA_RS22025	COG1136	(ABC) transporter
VEA_RS22080	COG5002	protein histidine kinase activity
VEA_RS22080	COG3850	Histidine kinase
VEA_RS22090	COG0840	transmembrane signaling receptor activity
VEA_RS22120	COG1032	radical SAM domain protein
VEA_RS22135	COG2200	EAL domain
VEA_RS22135	COG2199	diguanylate cyclase activity
VEA_RS22135	COG2203	Gaf domain
VEA_RS22240	COG0159	tryptophan synthase activity
VEA_RS22615	COG2205	protein histidine kinase activity
VEA_RS22615	COG0784	Response regulator, receiver
VEA_RS22910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair