locus-tag	class	description
VIBHAR_RS00020	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VIBHAR_RS00040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VIBHAR_RS00045	COG0735	belongs to the Fur family
VIBHAR_RS00060	COG0432	Pfam Uncharacterised protein family UPF0047
VIBHAR_RS00070	COG3385	transposase activity
VIBHAR_RS00075	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VIBHAR_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
VIBHAR_RS00100	COG2965	DNA replication, synthesis of RNA primer
VIBHAR_RS00110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VIBHAR_RS00115	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VIBHAR_RS00160	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VIBHAR_RS00170	COG0678	peroxiredoxin activity
VIBHAR_RS00170	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VIBHAR_RS00175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VIBHAR_RS00185	COG0165	Argininosuccinate lyase
VIBHAR_RS00185	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VIBHAR_RS00200	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VIBHAR_RS00210	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VIBHAR_RS00220	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VIBHAR_RS00225	COG0527	aspartate kinase activity
VIBHAR_RS00225	COG0460	homoserine dehydrogenase
VIBHAR_RS00230	COG0626	cystathionine gamma-synthase activity
VIBHAR_RS00240	COG0281	malic enzyme
VIBHAR_RS00250	COG2906	2 iron, 2 sulfur cluster binding
VIBHAR_RS00260	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VIBHAR_RS00275	COG2168	tRNA wobble position uridine thiolation
VIBHAR_RS00280	COG2923	Belongs to the DsrF TusC family
VIBHAR_RS00285	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VIBHAR_RS00290	COG2964	Protein conserved in bacteria
VIBHAR_RS00295	COG0545	Peptidyl-prolyl cis-trans isomerase
VIBHAR_RS00310	COG1446	asparaginase
VIBHAR_RS00315	COG1047	Peptidyl-prolyl cis-trans
VIBHAR_RS00330	COG2249	NAD(P)H dehydrogenase (quinone) activity
VIBHAR_RS00335	COG0488	(ABC) transporter
VIBHAR_RS00345	COG0429	hydrolase of the alpha beta-hydrolase fold
VIBHAR_RS00355	COG3954	Phosphoribulokinase
VIBHAR_RS00360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VIBHAR_RS00380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VIBHAR_RS00385	COG0512	Glutamine amidotransferase of anthranilate synthase
VIBHAR_RS00400	COG0546	phosphoglycolate phosphatase activity
VIBHAR_RS00405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VIBHAR_RS00410	COG0557	exoribonuclease II activity
VIBHAR_RS00420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VIBHAR_RS00420	COG1017	nitric oxide dioxygenase activity
VIBHAR_RS00425	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VIBHAR_RS00430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VIBHAR_RS00435	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VIBHAR_RS00440	COG0330	HflC and HflK could
VIBHAR_RS00445	COG0330	HflC and HflK could
VIBHAR_RS00450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VIBHAR_RS00465	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VIBHAR_RS00470	COG0860	N-Acetylmuramoyl-L-alanine amidase
VIBHAR_RS00475	COG0802	atpase or kinase
VIBHAR_RS00480	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VIBHAR_RS00550	COG1162	GTPase activity
VIBHAR_RS00570	COG0471	metal ion transport
VIBHAR_RS00590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VIBHAR_RS00605	COG1045	serine acetyltransferase
VIBHAR_RS00610	COG4942	peptidase
VIBHAR_RS00635	COG1053	succinate dehydrogenase
VIBHAR_RS00640	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VIBHAR_RS00670	COG1509	lysine 2,3-aminomutase activity
VIBHAR_RS00685	COG3344	reverse transcriptase
VIBHAR_RS00700	COG0534	Mate efflux family protein
VIBHAR_RS00725	COG0745	RESPONSE REGULATOR receiver
VIBHAR_RS00730	COG2205	protein histidine kinase activity
VIBHAR_RS00740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VIBHAR_RS00745	COG3030	protein affecting phage T7 exclusion by the F plasmid
VIBHAR_RS00750	COG1027	Aspartate ammonia-lyase
VIBHAR_RS00755	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VIBHAR_RS00760	COG4232	protein-disulfide reductase activity
VIBHAR_RS00770	COG2095	MarC family integral membrane protein
VIBHAR_RS00780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VIBHAR_RS00800	COG0784	Response regulator, receiver
VIBHAR_RS00800	COG2205	protein histidine kinase activity
VIBHAR_RS00805	COG2814	Major facilitator Superfamily
VIBHAR_RS00820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VIBHAR_RS00825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VIBHAR_RS00830	COG0511	ligase activity, forming carbon-carbon bonds
VIBHAR_RS00835	COG0439	Biotin carboxylase
VIBHAR_RS00845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VIBHAR_RS00850	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VIBHAR_RS00855	COG2199	diguanylate cyclase activity
VIBHAR_RS00865	COG2433	Pfam Transposase IS66
VIBHAR_RS00880	COG4584	PFAM Integrase catalytic
VIBHAR_RS00885	COG1484	DNA-dependent DNA replication
VIBHAR_RS00890	COG3335	DDE superfamily endonuclease
VIBHAR_RS00905	COG3335	DDE superfamily endonuclease
VIBHAR_RS00915	COG3335	DDE superfamily endonuclease
VIBHAR_RS00925	COG3335	DDE superfamily endonuclease
VIBHAR_RS00980	COG1982	Orn Lys Arg decarboxylase major
VIBHAR_RS00985	COG0531	amino acid
VIBHAR_RS00990	COG3710	Transcriptional regulator
VIBHAR_RS00995	COG0789	Transcriptional regulator
VIBHAR_RS01005	COG0151	Belongs to the GarS family
VIBHAR_RS01020	COG1253	flavin adenine dinucleotide binding
VIBHAR_RS01025	COG3068	Protein conserved in bacteria
VIBHAR_RS01035	COG1573	uracil-dna glycosylase
VIBHAR_RS01055	COG2816	NAD+ diphosphatase activity
VIBHAR_RS01060	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VIBHAR_RS01080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VIBHAR_RS01095	COG0250	Participates in transcription elongation, termination and antitermination
VIBHAR_RS01100	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VIBHAR_RS01140	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VIBHAR_RS01150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VIBHAR_RS01240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VIBHAR_RS01245	COG0534	Mate efflux family protein
VIBHAR_RS01260	COG2937	Belongs to the GPAT DAPAT family
VIBHAR_RS01275	COG3161	chorismate lyase activity
VIBHAR_RS01280	COG1580	Controls the rotational direction of flagella during chemotaxis
VIBHAR_RS01285	COG0705	Rhomboid family
VIBHAR_RS01300	COG2177	Part of the ABC transporter FtsEX involved in
VIBHAR_RS01305	COG2884	Cell division ATP-binding protein ftsE
VIBHAR_RS01310	COG0552	protein localization to endoplasmic reticulum
VIBHAR_RS01315	COG0742	ribosomal rna small subunit methyltransferase
VIBHAR_RS01325	COG2095	MarC family integral membrane protein
VIBHAR_RS01345	COG3293	Transposase
VIBHAR_RS01380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VIBHAR_RS01385	COG0640	Transcriptional regulator
VIBHAR_RS01390	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VIBHAR_RS01395	COG1280	lysine exporter protein (LysE YggA)
VIBHAR_RS01400	COG2267	carboxylic ester hydrolase activity
VIBHAR_RS01405	COG0561	phosphatase activity
VIBHAR_RS01420	COG3148	PFAM DTW domain containing protein
VIBHAR_RS01425	COG2199	diguanylate cyclase activity
VIBHAR_RS01425	COG2200	EAL domain
VIBHAR_RS01425	COG3287	FIST C domain
VIBHAR_RS01430	COG1011	Hydrolase
VIBHAR_RS01450	COG0019	diaminopimelate decarboxylase activity
VIBHAR_RS01465	COG3072	Adenylate cyclase
VIBHAR_RS01475	COG1587	Uroporphyrinogen-III synthase
VIBHAR_RS01480	COG2959	enzyme of heme biosynthesis
VIBHAR_RS01485	COG3071	HemY protein
VIBHAR_RS01495	COG3335	DDE superfamily endonuclease
VIBHAR_RS01505	COG3335	DDE superfamily endonuclease
VIBHAR_RS01515	COG3335	DDE superfamily endonuclease
VIBHAR_RS01555	COG0633	Ferredoxin
VIBHAR_RS01560	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VIBHAR_RS01575	COG3118	belongs to the thioredoxin family
VIBHAR_RS01595	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VIBHAR_RS01605	COG0514	ATP-dependent DNA helicase (RecQ)
VIBHAR_RS01610	COG2962	Rard protein
VIBHAR_RS01620	COG1280	lysine exporter protein (LysE YggA)
VIBHAR_RS01625	COG0405	Gamma-glutamyltransferase
VIBHAR_RS01630	COG3344	reverse transcriptase
VIBHAR_RS01635	COG0210	DNA helicase
VIBHAR_RS01645	COG3220	belongs to the UPF0276 family
VIBHAR_RS01665	COG2814	Major facilitator Superfamily
VIBHAR_RS01675	COG0006	proline dipeptidase activity
VIBHAR_RS01675	COG0006	proline dipeptidase activity
VIBHAR_RS01690	COG2104	thiamine diphosphate biosynthetic process
VIBHAR_RS01695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VIBHAR_RS01715	COG2132	Multicopper oxidase
VIBHAR_RS01725	COG3335	DDE superfamily endonuclease
VIBHAR_RS01735	COG3335	DDE superfamily endonuclease
VIBHAR_RS01775	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VIBHAR_RS01800	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VIBHAR_RS01805	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VIBHAR_RS01810	COG0551	DNA topoisomerase type I activity
VIBHAR_RS01820	COG0758	DNA mediated transformation
VIBHAR_RS01840	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VIBHAR_RS01840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VIBHAR_RS01845	COG0569	domain protein
VIBHAR_RS01850	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VIBHAR_RS01860	COG1272	protein, Hemolysin III
VIBHAR_RS01865	COG4326	sporulation control protein
VIBHAR_RS01870	COG3084	Protein conserved in bacteria
VIBHAR_RS01880	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VIBHAR_RS01885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VIBHAR_RS01890	COG3385	transposase activity
VIBHAR_RS01895	COG0204	Acyl-transferase
VIBHAR_RS01905	COG2199	diguanylate cyclase activity
VIBHAR_RS01910	COG0606	chelatase, subunit chli
VIBHAR_RS01920	COG3978	acetolactate synthase activity
VIBHAR_RS01925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VIBHAR_RS01930	COG0129	dihydroxy-acid dehydratase activity
VIBHAR_RS01940	COG0583	DNA-binding transcription factor activity
VIBHAR_RS01945	COG2814	Major facilitator Superfamily
VIBHAR_RS01950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VIBHAR_RS01955	COG0765	amino acid transport
VIBHAR_RS01965	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VIBHAR_RS01975	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VIBHAR_RS02005	COG3312	ion transport
VIBHAR_RS02010	COG1475	DNA binding
VIBHAR_RS02015	COG1192	Involved in chromosome partitioning
VIBHAR_RS02030	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VIBHAR_RS02055	COG1126	abc transporter atp-binding protein
VIBHAR_RS02075	COG0592	DNA-directed DNA polymerase activity
VIBHAR_RS02085	COG0187	DNA topoisomerase II activity
VIBHAR_RS02090	COG0071	Belongs to the small heat shock protein (HSP20) family
VIBHAR_RS02095	COG3977	Valine--pyruvate aminotransferase
VIBHAR_RS02100	COG3385	transposase activity
VIBHAR_RS02115	COG2119	membrane
VIBHAR_RS02150	COG0604	alcohol dehydrogenase
VIBHAR_RS02155	COG0183	Belongs to the thiolase family
VIBHAR_RS02165	COG1739	Uncharacterized protein family UPF0029
VIBHAR_RS02170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VIBHAR_RS02220	COG3335	DDE superfamily endonuclease
VIBHAR_RS02225	COG3335	DDE superfamily endonuclease
VIBHAR_RS02235	COG0583	DNA-binding transcription factor activity
VIBHAR_RS02240	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VIBHAR_RS02245	COG2960	long-chain fatty acid transporting porin activity
VIBHAR_RS02250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VIBHAR_RS02255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VIBHAR_RS02315	COG4166	transmembrane transport
VIBHAR_RS02320	COG0601	transmembrane transport
VIBHAR_RS02325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VIBHAR_RS02375	COG0515	serine threonine protein kinase
VIBHAR_RS02380	COG1609	Transcriptional regulator
VIBHAR_RS02385	COG0583	DNA-binding transcription factor activity
VIBHAR_RS02390	COG2076	Multidrug Resistance protein
VIBHAR_RS02400	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS02405	COG0129	dihydroxy-acid dehydratase activity
VIBHAR_RS02410	COG3265	gluconokinase activity
VIBHAR_RS02415	COG2610	gluconate transmembrane transporter activity
VIBHAR_RS02420	COG0800	Aldolase
VIBHAR_RS02440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VIBHAR_RS02450	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VIBHAR_RS02465	COG1522	sequence-specific DNA binding
VIBHAR_RS02470	COG5001	Diguanylate cyclase
VIBHAR_RS02470	COG5002	protein histidine kinase activity
VIBHAR_RS02490	COG0589	response to stress
VIBHAR_RS02500	COG1528	Iron-storage protein
VIBHAR_RS02510	COG2081	HI0933 family
VIBHAR_RS02530	COG4372	Transposase
VIBHAR_RS02565	COG3469	chitinase activity
VIBHAR_RS02600	COG1910	domain protein
VIBHAR_RS02605	COG3293	Transposase
VIBHAR_RS02610	COG3385	transposase activity
VIBHAR_RS02625	COG1322	Protein conserved in bacteria
VIBHAR_RS02635	COG3165	ubiquinone biosynthetic process from chorismate
VIBHAR_RS02650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VIBHAR_RS02655	COG0805	protein transport
VIBHAR_RS02660	COG0084	hydrolase, TatD family'
VIBHAR_RS02675	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VIBHAR_RS02675	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VIBHAR_RS02680	COG0218	Necessary for normal cell division and for the maintenance of normal septation
VIBHAR_RS02710	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VIBHAR_RS02720	COG2204	response regulator
VIBHAR_RS02725	COG3852	Histidine kinase
VIBHAR_RS02740	COG0174	glutamine synthetase
VIBHAR_RS02750	COG1217	gtp-binding protein TYPA
VIBHAR_RS02770	COG1490	D-aminoacyl-tRNA deacylase activity
VIBHAR_RS02775	COG0456	acetyltransferase
VIBHAR_RS02795	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VIBHAR_RS02800	COG3031	protein transport across the cell outer membrane
VIBHAR_RS02810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VIBHAR_RS02815	COG1459	type II secretion system
VIBHAR_RS02820	COG2165	general secretion pathway protein
VIBHAR_RS02825	COG2165	general secretion pathway protein
VIBHAR_RS02830	COG2165	general secretion pathway protein
VIBHAR_RS02835	COG4795	General secretion pathway protein
VIBHAR_RS02840	COG3156	type II secretion system protein K
VIBHAR_RS02845	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VIBHAR_RS02850	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VIBHAR_RS02860	COG1218	3'(2'),5'-bisphosphate nucleotidase
VIBHAR_RS02865	COG0494	nUDIX hydrolase
VIBHAR_RS02875	COG1040	competence protein
VIBHAR_RS02890	COG2183	response to ionizing radiation
VIBHAR_RS02900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VIBHAR_RS02915	COG2233	PERMEase
VIBHAR_RS02925	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VIBHAR_RS02930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VIBHAR_RS02935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VIBHAR_RS02945	COG0194	GDP metabolic process
VIBHAR_RS02960	COG0848	biopolymer transport protein
VIBHAR_RS02965	COG0811	peptide transport
VIBHAR_RS02985	COG4174	ABC transporter (Permease)
VIBHAR_RS02990	COG4239	(ABC) transporter, permease
VIBHAR_RS02995	COG0747	negative chemotaxis
VIBHAR_RS03000	COG0444	Belongs to the ABC transporter superfamily
VIBHAR_RS03005	COG4608	Belongs to the ABC transporter superfamily
VIBHAR_RS03025	COG1561	YicC-like family, N-terminal region
VIBHAR_RS03030	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VIBHAR_RS03035	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VIBHAR_RS03040	COG1560	Kdo2-lipid A biosynthetic process
VIBHAR_RS03050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VIBHAR_RS03090	COG0438	transferase activity, transferring glycosyl groups
VIBHAR_RS03095	COG0463	Glycosyl transferase, family 2
VIBHAR_RS03100	COG0859	PFAM glycosyl transferase family 9
VIBHAR_RS03105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VIBHAR_RS03110	COG3642	lipopolysaccharide core region biosynthetic process
VIBHAR_RS03130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VIBHAR_RS03140	COG2089	acid synthase
VIBHAR_RS03145	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VIBHAR_RS03165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VIBHAR_RS03175	COG1083	cytidylyl-transferase
VIBHAR_RS03185	COG1519	Transferase
VIBHAR_RS03195	COG1560	Kdo2-lipid A biosynthetic process
VIBHAR_RS03205	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VIBHAR_RS03240	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VIBHAR_RS03245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VIBHAR_RS03315	COG1482	cell wall glycoprotein biosynthetic process
VIBHAR_RS03320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VIBHAR_RS03340	COG0149	triose-phosphate isomerase activity
VIBHAR_RS03355	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS03370	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS03375	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS03380	COG1494	fructose-1,6-bisphosphatase
VIBHAR_RS03390	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VIBHAR_RS03395	COG1575	Belongs to the MenA family. Type 1 subfamily
VIBHAR_RS03415	COG1609	Transcriptional regulator
VIBHAR_RS03420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VIBHAR_RS03525	COG1841	ribosomal large subunit assembly
VIBHAR_RS03535	COG0201	protein transport
VIBHAR_RS03540	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VIBHAR_RS03545	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VIBHAR_RS03550	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VIBHAR_RS03565	COG0203	ribosomal protein L17
VIBHAR_RS03575	COG0545	Peptidyl-prolyl cis-trans isomerase
VIBHAR_RS03585	COG3344	reverse transcriptase
VIBHAR_RS03595	COG2153	protein acetylation
VIBHAR_RS03600	COG0513	Belongs to the DEAD box helicase family
VIBHAR_RS03610	COG0737	Belongs to the 5'-nucleotidase family
VIBHAR_RS03615	COG1648	precorrin-2 dehydrogenase activity
VIBHAR_RS03615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VIBHAR_RS03630	COG3273	potassium ion transport
VIBHAR_RS03630	COG0471	metal ion transport
VIBHAR_RS03635	COG0529	Catalyzes the synthesis of activated sulfate
VIBHAR_RS03655	COG1136	(ABC) transporter
VIBHAR_RS03665	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VIBHAR_RS03675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VIBHAR_RS03680	COG0729	surface antigen
VIBHAR_RS03690	COG2105	PFAM AIG2 family protein
VIBHAR_RS03700	COG3385	transposase activity
VIBHAR_RS03705	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VIBHAR_RS03715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VIBHAR_RS03720	COG0163	prenyltransferase activity
VIBHAR_RS03725	COG4143	(ABC) transporter
VIBHAR_RS03730	COG1178	ABC-type Fe3 transport system permease component
VIBHAR_RS03735	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VIBHAR_RS03750	COG2358	TRAP transporter, solute receptor (TAXI family
VIBHAR_RS03770	COG3385	transposase activity
VIBHAR_RS03775	COG0142	geranyltranstransferase activity
VIBHAR_RS03780	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VIBHAR_RS03795	COG2966	Psort location CytoplasmicMembrane, score
VIBHAR_RS03800	COG3610	response to peptide
VIBHAR_RS03825	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VIBHAR_RS03830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VIBHAR_RS03835	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VIBHAR_RS03840	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VIBHAR_RS03860	COG0473	3-isopropylmalate dehydrogenase activity
VIBHAR_RS03865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VIBHAR_RS03895	COG0583	DNA-binding transcription factor activity
VIBHAR_RS03900	COG1022	Amp-dependent synthetase and ligase
VIBHAR_RS03905	COG0028	Belongs to the TPP enzyme family
VIBHAR_RS03910	COG0440	acetolactate synthase activity
VIBHAR_RS03915	COG3706	GGDEF domain
VIBHAR_RS03925	COG0469	pyruvate kinase activity
VIBHAR_RS03930	COG1349	DNA-binding transcription factor activity
VIBHAR_RS03935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VIBHAR_RS03940	COG3722	fumarate hydratase activity
VIBHAR_RS03950	COG2213	PTS system mannitol-specific
VIBHAR_RS03950	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VIBHAR_RS03975	COG0582	viral genome integration into host DNA
VIBHAR_RS03995	COG2433	Pfam Transposase IS66
VIBHAR_RS04020	COG0358	DNA primase activity
VIBHAR_RS04025	COG1610	YqeY-like protein
VIBHAR_RS04030	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VIBHAR_RS04035	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VIBHAR_RS04040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
VIBHAR_RS04050	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VIBHAR_RS04055	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VIBHAR_RS04070	COG3409	Peptidoglycan-binding domain 1 protein
VIBHAR_RS04070	COG3267	Type II secretory pathway component ExeA
VIBHAR_RS04080	COG4991	sh3 domain protein
VIBHAR_RS04085	COG0306	phosphate transporter
VIBHAR_RS04090	COG1392	Phosphate transport regulator
VIBHAR_RS04095	COG3025	triphosphatase activity
VIBHAR_RS04100	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VIBHAR_RS04110	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VIBHAR_RS04120	COG1538	Outer membrane efflux protein
VIBHAR_RS04125	COG0494	nUDIX hydrolase
VIBHAR_RS04130	COG3151	Protein conserved in bacteria
VIBHAR_RS04140	COG3150	esterase
VIBHAR_RS04150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VIBHAR_RS04155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VIBHAR_RS04160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VIBHAR_RS04165	COG3105	Protein conserved in bacteria
VIBHAR_RS04170	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VIBHAR_RS04185	COG0723	plastoquinol--plastocyanin reductase activity
VIBHAR_RS04190	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VIBHAR_RS04195	COG2857	Cytochrome c1
VIBHAR_RS04200	COG0625	glutathione transferase activity
VIBHAR_RS04205	COG2969	positive regulation of protein catabolic process
VIBHAR_RS04210	COG2823	Periplasmic or secreted lipoprotein
VIBHAR_RS04215	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VIBHAR_RS04230	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VIBHAR_RS04240	COG3116	cell division
VIBHAR_RS04245	COG0768	penicillin binding
VIBHAR_RS04250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VIBHAR_RS04255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VIBHAR_RS04270	COG0772	Belongs to the SEDS family
VIBHAR_RS04285	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VIBHAR_RS04290	COG0849	cell division
VIBHAR_RS04295	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VIBHAR_RS04315	COG0494	nUDIX hydrolase
VIBHAR_RS04325	COG0505	Belongs to the CarA family
VIBHAR_RS04330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VIBHAR_RS04345	COG0730	response to heat
VIBHAR_RS04350	COG0583	DNA-binding transcription factor activity
VIBHAR_RS04355	COG2860	membrane
VIBHAR_RS04380	COG0493	'glutamate synthase
VIBHAR_RS04385	COG0069	glutamate synthase activity
VIBHAR_RS04385	COG0070	glutamate synthase
VIBHAR_RS04385	COG0067	glutamate synthase
VIBHAR_RS04395	COG0067	glutamate synthase
VIBHAR_RS04395	COG0069	glutamate synthase activity
VIBHAR_RS04395	COG0070	glutamate synthase
VIBHAR_RS04400	COG1242	4 iron, 4 sulfur cluster binding
VIBHAR_RS04405	COG3706	GGDEF domain
VIBHAR_RS04405	COG2203	Gaf domain
VIBHAR_RS04405	COG4251	negative regulation of phosphorylation
VIBHAR_RS04405	COG5001	Diguanylate cyclase
VIBHAR_RS04410	COG0784	Response regulator, receiver
VIBHAR_RS04410	COG2198	Histidine kinase
VIBHAR_RS04410	COG5002	protein histidine kinase activity
VIBHAR_RS04420	COG0745	RESPONSE REGULATOR receiver
VIBHAR_RS04425	COG3385	transposase activity
VIBHAR_RS04435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VIBHAR_RS04450	COG0083	homoserine kinase activity
VIBHAR_RS04455	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VIBHAR_RS04490	COG1115	amino acid carrier protein
VIBHAR_RS04495	COG3022	response to hydroperoxide
VIBHAR_RS04510	COG0513	Belongs to the DEAD box helicase family
VIBHAR_RS04525	COG0716	FMN binding
VIBHAR_RS04530	COG4974	Belongs to the 'phage' integrase family
VIBHAR_RS04535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VIBHAR_RS04540	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VIBHAR_RS04545	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VIBHAR_RS04565	COG0667	Aldo Keto reductase
VIBHAR_RS04590	COG0730	response to heat
VIBHAR_RS04605	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS04610	COG1283	sodium-dependent phosphate transmembrane transporter activity
VIBHAR_RS04615	COG0583	DNA-binding transcription factor activity
VIBHAR_RS04620	COG0640	Transcriptional regulator
VIBHAR_RS04625	COG0268	Binds directly to 16S ribosomal RNA
VIBHAR_RS04630	COG0728	peptidoglycan biosynthetic process
VIBHAR_RS04635	COG0196	riboflavin kinase activity
VIBHAR_RS04650	COG1047	Peptidyl-prolyl cis-trans
VIBHAR_RS04655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VIBHAR_RS04660	COG3279	Response regulator of the LytR AlgR family
VIBHAR_RS04665	COG3275	phosphorelay sensor kinase activity
VIBHAR_RS04670	COG1966	Carbon starvation protein
VIBHAR_RS04690	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VIBHAR_RS04700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VIBHAR_RS04705	COG0287	Prephenate dehydrogenase
VIBHAR_RS04705	COG1605	Chorismate mutase
VIBHAR_RS04710	COG3385	transposase activity
VIBHAR_RS04715	COG0739	heme binding
VIBHAR_RS04725	COG0488	(ABC) transporter
VIBHAR_RS04740	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
VIBHAR_RS04745	COG0077	Prephenate dehydratase
VIBHAR_RS04745	COG1605	Chorismate mutase
VIBHAR_RS04750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VIBHAR_RS04755	COG0741	lytic transglycosylase activity
VIBHAR_RS04760	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VIBHAR_RS04765	COG0564	pseudouridine synthase activity
VIBHAR_RS04770	COG1496	oxidoreductase activity
VIBHAR_RS04775	COG0542	response to heat
VIBHAR_RS04820	COG3335	DDE superfamily endonuclease
VIBHAR_RS04845	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VIBHAR_RS04850	COG0826	peptidase U32
VIBHAR_RS04860	COG0745	RESPONSE REGULATOR receiver
VIBHAR_RS04865	COG5002	protein histidine kinase activity
VIBHAR_RS04875	COG0248	Ppx GppA phosphatase
VIBHAR_RS04880	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VIBHAR_RS04885	COG0573	inorganic phosphate transmembrane transporter activity
VIBHAR_RS04890	COG0581	inorganic phosphate transmembrane transporter activity
VIBHAR_RS04895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VIBHAR_RS04900	COG0704	Plays a role in the regulation of phosphate uptake
VIBHAR_RS04910	COG3335	DDE superfamily endonuclease
VIBHAR_RS04925	COG0450	alkyl hydroperoxide reductase
VIBHAR_RS04930	COG0583	DNA-binding transcription factor activity
VIBHAR_RS04935	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VIBHAR_RS04945	COG0517	IMP dehydrogenase activity
VIBHAR_RS04965	COG1862	Preprotein translocase
VIBHAR_RS04970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VIBHAR_RS04975	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VIBHAR_RS04990	COG0483	inositol monophosphate 1-phosphatase activity
VIBHAR_RS04995	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
VIBHAR_RS05010	COG0822	iron-sulfur transferase activity
VIBHAR_RS05015	COG0316	Belongs to the HesB IscA family
VIBHAR_RS05030	COG0633	Ferredoxin
VIBHAR_RS05035	COG2975	iron-sulfur cluster assembly
VIBHAR_RS05040	COG3385	transposase activity
VIBHAR_RS05075	COG2976	Protein conserved in bacteria
VIBHAR_RS05080	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VIBHAR_RS05105	COG0517	IMP dehydrogenase activity
VIBHAR_RS05105	COG0516	GMP reductase activity
VIBHAR_RS05115	COG1757	Na H antiporter
VIBHAR_RS05120	COG3385	transposase activity
VIBHAR_RS05125	COG1757	Na H antiporter
VIBHAR_RS05135	COG1584	GPR1 FUN34 yaaH family protein
VIBHAR_RS05140	COG3344	reverse transcriptase
VIBHAR_RS05145	COG1115	amino acid carrier protein
VIBHAR_RS05155	COG0583	DNA-binding transcription factor activity
VIBHAR_RS05160	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VIBHAR_RS05165	COG0668	transmembrane transport
VIBHAR_RS05170	COG3335	DDE superfamily endonuclease
VIBHAR_RS05175	COG3344	reverse transcriptase
VIBHAR_RS05230	COG2433	Pfam Transposase IS66
VIBHAR_RS05245	COG1289	transmembrane transporter activity
VIBHAR_RS05250	COG0583	DNA-binding transcription factor activity
VIBHAR_RS05300	COG3385	transposase activity
VIBHAR_RS05305	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VIBHAR_RS05320	COG0582	viral genome integration into host DNA
VIBHAR_RS05330	COG2867	negative regulation of translational initiation
VIBHAR_RS05335	COG2914	Belongs to the UPF0125 (RnfH) family
VIBHAR_RS05345	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VIBHAR_RS05350	COG0456	acetyltransferase
VIBHAR_RS05355	COG0497	DNA recombination
VIBHAR_RS05370	COG1301	dicarboxylic acid transport
VIBHAR_RS05410	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VIBHAR_RS05415	COG0590	tRNA wobble adenosine to inosine editing
VIBHAR_RS05430	COG2433	Pfam Transposase IS66
VIBHAR_RS05440	COG2433	Pfam Transposase IS66
VIBHAR_RS05450	COG0047	phosphoribosylformylglycinamidine synthase activity
VIBHAR_RS05450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VIBHAR_RS05460	COG3293	Transposase
VIBHAR_RS05480	COG3385	transposase activity
VIBHAR_RS05485	COG2195	Cleaves the N-terminal amino acid of tripeptides
VIBHAR_RS05490	COG2252	PERMEase
VIBHAR_RS05500	COG1073	alpha beta
VIBHAR_RS05515	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VIBHAR_RS05520	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VIBHAR_RS05525	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VIBHAR_RS05525	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VIBHAR_RS05550	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VIBHAR_RS05555	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VIBHAR_RS05565	COG0142	geranyltranstransferase activity
VIBHAR_RS05575	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VIBHAR_RS05600	COG2433	Pfam Transposase IS66
VIBHAR_RS05605	COG0583	DNA-binding transcription factor activity
VIBHAR_RS05615	COG2363	Small membrane protein
VIBHAR_RS05625	COG3293	Transposase
VIBHAR_RS05635	COG1611	Belongs to the LOG family
VIBHAR_RS05660	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VIBHAR_RS05675	COG1464	Belongs to the NlpA lipoprotein family
VIBHAR_RS05680	COG2011	ABC-type metal ion transport system permease component
VIBHAR_RS05685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VIBHAR_RS05690	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VIBHAR_RS05700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VIBHAR_RS05700	COG1263	PTS System
VIBHAR_RS05705	COG0366	Alpha amylase catalytic
VIBHAR_RS05710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
VIBHAR_RS05715	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VIBHAR_RS05720	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS05725	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS05745	COG1686	Belongs to the peptidase S11 family
VIBHAR_RS05750	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VIBHAR_RS05755	COG0772	Belongs to the SEDS family
VIBHAR_RS05760	COG0768	penicillin binding
VIBHAR_RS05770	COG0799	negative regulation of ribosome biogenesis
VIBHAR_RS05775	COG1466	dna polymerase III delta subunit
VIBHAR_RS05780	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VIBHAR_RS05790	COG2888	peptidyl-tyrosine sulfation
VIBHAR_RS05805	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VIBHAR_RS05810	COG4535	Mg2 and Co2 transporter CorC
VIBHAR_RS05820	COG1702	phosphate starvation-inducible protein PhoH
VIBHAR_RS05830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VIBHAR_RS05885	COG0012	GTP binding
VIBHAR_RS05895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VIBHAR_RS05920	COG2890	protein-(glutamine-N5) methyltransferase activity
VIBHAR_RS05925	COG3094	Invasion gene expression up-regulator, SirB
VIBHAR_RS05930	COG2912	Transglutaminase-like superfamily
VIBHAR_RS05940	COG0737	Belongs to the 5'-nucleotidase family
VIBHAR_RS05945	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VIBHAR_RS05950	COG1187	pseudouridine synthase activity
VIBHAR_RS05955	COG2840	Smr protein MutS2
VIBHAR_RS06000	COG2608	mercury ion transmembrane transporter activity
VIBHAR_RS06000	COG2217	Heavy metal translocating P-type atpase
VIBHAR_RS06010	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VIBHAR_RS06070	COG0835	chemotaxis
VIBHAR_RS06070	COG0784	Response regulator, receiver
VIBHAR_RS06075	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VIBHAR_RS06080	COG1815	bacterial-type flagellum-dependent cell motility
VIBHAR_RS06085	COG1558	bacterial-type flagellum-dependent cell motility
VIBHAR_RS06095	COG1749	Flagellar hook protein flgE
VIBHAR_RS06100	COG4787	bacterial-type flagellum-dependent cell motility
VIBHAR_RS06110	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VIBHAR_RS06115	COG1706	bacterial-type flagellum-dependent cell motility
VIBHAR_RS06120	COG3951	Flagellar rod assembly protein muramidase FlgJ
VIBHAR_RS06120	COG1705	Flagellar rod assembly protein muramidase FlgJ
VIBHAR_RS06125	COG3344	reverse transcriptase
VIBHAR_RS06140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VIBHAR_RS06145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VIBHAR_RS06150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VIBHAR_RS06160	COG3335	DDE superfamily endonuclease
VIBHAR_RS06165	COG3344	reverse transcriptase
VIBHAR_RS06170	COG2190	(PTS) system
VIBHAR_RS06175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VIBHAR_RS06180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VIBHAR_RS06185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VIBHAR_RS06190	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VIBHAR_RS06225	COG0330	HflC and HflK could
VIBHAR_RS06230	COG3118	belongs to the thioredoxin family
VIBHAR_RS06235	COG0300	oxidoreductase activity
VIBHAR_RS06240	COG1090	epimerase
VIBHAR_RS06250	COG0622	Phosphoesterase
VIBHAR_RS06270	COG3710	Transcriptional regulator
VIBHAR_RS06285	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VIBHAR_RS06290	COG3104	oligopeptide transport
VIBHAR_RS06300	COG0367	asparagine synthase
VIBHAR_RS06305	COG4651	solute:proton antiporter activity
VIBHAR_RS06305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VIBHAR_RS06310	COG1846	Transcriptional regulator
VIBHAR_RS06310	COG1940	carbohydrate kinase activity
VIBHAR_RS06315	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VIBHAR_RS06320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VIBHAR_RS06320	COG1263	PTS System
VIBHAR_RS06320	COG2190	(PTS) system
VIBHAR_RS06330	COG2165	general secretion pathway protein
VIBHAR_RS06335	COG0735	belongs to the Fur family
VIBHAR_RS06355	COG0596	Alpha beta hydrolase
VIBHAR_RS06360	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VIBHAR_RS06365	COG0033	Phosphoglucomutase
VIBHAR_RS06380	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VIBHAR_RS06385	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS06400	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VIBHAR_RS06405	COG1053	succinate dehydrogenase
VIBHAR_RS06415	COG0567	Dehydrogenase, E1 component
VIBHAR_RS06420	COG0508	dehydrogenase complex catalyzes the overall conversion of
VIBHAR_RS06435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VIBHAR_RS06440	COG1121	(ABC) transporter
VIBHAR_RS06445	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VIBHAR_RS06450	COG4977	sequence-specific DNA binding
VIBHAR_RS06455	COG1918	ferrous iron import across plasma membrane
VIBHAR_RS06485	COG3102	Protein conserved in bacteria
VIBHAR_RS06500	COG0788	formyltetrahydrofolate deformylase activity
VIBHAR_RS06505	COG1199	ATP-dependent helicase activity
VIBHAR_RS06510	COG1214	PFAM Peptidase M22, glycoprotease
VIBHAR_RS06520	COG3065	identical protein binding
VIBHAR_RS06525	COG2267	carboxylic ester hydrolase activity
VIBHAR_RS06530	COG0318	PFAM AMP-dependent synthetase and ligase
VIBHAR_RS06535	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VIBHAR_RS06540	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS06545	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS06550	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VIBHAR_RS06555	COG2894	cell division
VIBHAR_RS06570	COG2951	lytic endotransglycosylase activity
VIBHAR_RS06580	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VIBHAR_RS06610	COG1028	Short-chain dehydrogenase reductase Sdr
VIBHAR_RS06620	COG1169	isochorismate synthase
VIBHAR_RS06625	COG1021	2,3-dihydroxybenzoate-AMP ligase
VIBHAR_RS06630	COG1535	isochorismatase
VIBHAR_RS06630	COG3433	isochorismatase activity
VIBHAR_RS06635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VIBHAR_RS06635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VIBHAR_RS06645	COG2977	Belongs to the P-Pant transferase superfamily
VIBHAR_RS06650	COG4771	TonB-dependent receptor
VIBHAR_RS06655	COG0513	Belongs to the DEAD box helicase family
VIBHAR_RS06660	COG0569	domain protein
VIBHAR_RS06665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VIBHAR_RS06680	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VIBHAR_RS06710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VIBHAR_RS06715	COG0776	regulation of translation
VIBHAR_RS06720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VIBHAR_RS06725	COG1555	photosystem II stabilization
VIBHAR_RS06745	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VIBHAR_RS06750	COG0436	Aminotransferase
VIBHAR_RS06755	COG1169	isochorismate synthase
VIBHAR_RS06765	COG0596	Alpha beta hydrolase
VIBHAR_RS06770	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
VIBHAR_RS06795	COG2855	membrane
VIBHAR_RS06835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VIBHAR_RS06840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VIBHAR_RS06860	COG1522	sequence-specific DNA binding
VIBHAR_RS06865	COG1946	Acyl-CoA thioesterase
VIBHAR_RS06870	COG3126	Type III secretion system lipoprotein chaperone (YscW)
VIBHAR_RS06885	COG3706	GGDEF domain
VIBHAR_RS06915	COG2433	Pfam Transposase IS66
VIBHAR_RS06935	COG2433	Pfam Transposase IS66
VIBHAR_RS06965	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS07000	COG4372	Transposase
VIBHAR_RS07015	COG2433	Pfam Transposase IS66
VIBHAR_RS07020	COG2433	Pfam Transposase IS66
VIBHAR_RS07100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VIBHAR_RS07105	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VIBHAR_RS07110	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VIBHAR_RS07115	COG0517	IMP dehydrogenase activity
VIBHAR_RS07115	COG0516	GMP reductase activity
VIBHAR_RS07125	COG2217	Heavy metal translocating P-type atpase
VIBHAR_RS07145	COG0537	adenosine 5'-monophosphoramidase activity
VIBHAR_RS07175	COG1252	NADH dehydrogenase
VIBHAR_RS07190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VIBHAR_RS07200	COG4591	ABC-type transport system involved in lipoprotein release permease component
VIBHAR_RS07205	COG1136	(ABC) transporter
VIBHAR_RS07210	COG4591	ABC-type transport system involved in lipoprotein release permease component
VIBHAR_RS07220	COG2333	competence protein COMEC
VIBHAR_RS07220	COG0658	competence protein
VIBHAR_RS07225	COG1132	(ABC) transporter
VIBHAR_RS07245	COG2719	SpoVR family
VIBHAR_RS07250	COG2718	Belongs to the UPF0229 family
VIBHAR_RS07255	COG2766	serine protein kinase
VIBHAR_RS07270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VIBHAR_RS07280	COG1882	Formate acetyltransferase
VIBHAR_RS07315	COG0708	Exodeoxyribonuclease III
VIBHAR_RS07325	COG3923	Primosomal replication protein n
VIBHAR_RS07330	COG0730	response to heat
VIBHAR_RS07335	COG1199	ATP-dependent helicase activity
VIBHAR_RS07345	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VIBHAR_RS07350	COG1187	pseudouridine synthase activity
VIBHAR_RS07360	COG1278	Cold shock
VIBHAR_RS07370	COG0542	response to heat
VIBHAR_RS07375	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VIBHAR_RS07405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VIBHAR_RS07410	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VIBHAR_RS07415	COG0297	glycogen (starch) synthase activity
VIBHAR_RS07435	COG3070	regulator of competence-specific genes
VIBHAR_RS07450	COG0745	RESPONSE REGULATOR receiver
VIBHAR_RS07455	COG3385	transposase activity
VIBHAR_RS07460	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VIBHAR_RS07465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VIBHAR_RS07475	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VIBHAR_RS07480	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
VIBHAR_RS07495	COG4067	protein conserved in archaea
VIBHAR_RS07495	COG0189	ligase activity
VIBHAR_RS07510	COG1801	Protein of unknown function DUF72
VIBHAR_RS07525	COG0840	transmembrane signaling receptor activity
VIBHAR_RS07530	COG0632	four-way junction helicase activity
VIBHAR_RS07540	COG1271	oxidase subunit
VIBHAR_RS07545	COG1294	oxidase, subunit
VIBHAR_RS07560	COG0824	Thioesterase
VIBHAR_RS07565	COG0811	peptide transport
VIBHAR_RS07580	COG0823	Involved in the tonB-independent uptake of proteins
VIBHAR_RS07585	COG2885	chlorophyll binding
VIBHAR_RS07590	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
VIBHAR_RS07605	COG3766	membrane
VIBHAR_RS07615	COG0754	glutathionylspermidine amidase activity
VIBHAR_RS07625	COG2205	protein histidine kinase activity
VIBHAR_RS07625	COG0784	Response regulator, receiver
VIBHAR_RS07640	COG0582	viral genome integration into host DNA
VIBHAR_RS07655	COG2433	Pfam Transposase IS66
VIBHAR_RS07675	COG0280	phosphate acetyltransferase
VIBHAR_RS07680	COG3426	butyrate kinase activity
VIBHAR_RS07685	COG4689	acetoacetate decarboxylase
VIBHAR_RS07690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VIBHAR_RS07735	COG3335	DDE superfamily endonuclease
VIBHAR_RS07740	COG2433	Pfam Transposase IS66
VIBHAR_RS07785	COG2433	Pfam Transposase IS66
VIBHAR_RS07800	COG3335	DDE superfamily endonuclease
VIBHAR_RS07835	COG5433	transposase activity
VIBHAR_RS07905	COG3385	transposase activity
VIBHAR_RS08000	COG4669	(LipO)protein
VIBHAR_RS08030	COG3177	Filamentation induced by cAMP protein fic
VIBHAR_RS08040	COG3335	DDE superfamily endonuclease
VIBHAR_RS08055	COG3335	DDE superfamily endonuclease
VIBHAR_RS08075	COG0583	DNA-binding transcription factor activity
VIBHAR_RS08080	COG4792	protein secretion
VIBHAR_RS08085	COG4791	protein targeting
VIBHAR_RS08090	COG4794	Type iii secretion
VIBHAR_RS08095	COG4790	Type iii secretion
VIBHAR_RS08165	COG0457	Tetratricopeptide repeat
VIBHAR_RS08195	COG3385	transposase activity
VIBHAR_RS08215	COG2824	Alkylphosphonate utilization operon protein PhnA
VIBHAR_RS08230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VIBHAR_RS08235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VIBHAR_RS08245	COG2186	Transcriptional regulator
VIBHAR_RS08255	COG1288	antiporter activity
VIBHAR_RS08275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VIBHAR_RS08280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VIBHAR_RS08285	COG1120	ATPase activity
VIBHAR_RS08300	COG3293	Transposase
VIBHAR_RS08325	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS08335	COG3568	Endonuclease Exonuclease Phosphatase
VIBHAR_RS08360	COG2433	Pfam Transposase IS66
VIBHAR_RS08380	COG0402	S-adenosylhomocysteine deaminase activity
VIBHAR_RS08395	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS08410	COG0583	DNA-binding transcription factor activity
VIBHAR_RS08420	COG0686	Belongs to the AlaDH PNT family
VIBHAR_RS08430	COG1674	ftsk spoiiie
VIBHAR_RS08440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VIBHAR_RS08450	COG3335	DDE superfamily endonuclease
VIBHAR_RS08470	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VIBHAR_RS08490	COG2226	methyltransferase
VIBHAR_RS08500	COG3344	reverse transcriptase
VIBHAR_RS08515	COG0300	oxidoreductase activity
VIBHAR_RS08530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VIBHAR_RS08550	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VIBHAR_RS08570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VIBHAR_RS08580	COG1757	Na H antiporter
VIBHAR_RS08590	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VIBHAR_RS08600	COG0131	Imidazoleglycerol-phosphate dehydratase
VIBHAR_RS08600	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VIBHAR_RS08605	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VIBHAR_RS08620	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VIBHAR_RS08620	COG0140	phosphoribosyl-ATP diphosphatase activity
VIBHAR_RS08625	COG3012	SEC-C Motif Domain Protein
VIBHAR_RS08630	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VIBHAR_RS08635	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VIBHAR_RS08640	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VIBHAR_RS08645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VIBHAR_RS08650	COG0215	cysteine-tRNA ligase activity
VIBHAR_RS08655	COG1435	thymidine kinase activity
VIBHAR_RS08670	COG3344	reverse transcriptase
VIBHAR_RS08675	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VIBHAR_RS08700	COG2116	formate transmembrane transporter activity
VIBHAR_RS08705	COG0390	transport system, permease component
VIBHAR_RS08710	COG4459	periplasmic nitrate reductase
VIBHAR_RS08720	COG0243	molybdopterin cofactor binding
VIBHAR_RS08735	COG1227	inorganic diphosphatase activity
VIBHAR_RS08765	COG4172	Belongs to the ABC transporter superfamily
VIBHAR_RS08775	COG4171	peptide transport system, permease
VIBHAR_RS08780	COG4168	peptide transport system, permease
VIBHAR_RS08790	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VIBHAR_RS08795	COG1842	Phage shock protein A
VIBHAR_RS08805	COG1983	PspC domain protein
VIBHAR_RS08825	COG2818	Glycosylase
VIBHAR_RS08835	COG3335	DDE superfamily endonuclease
VIBHAR_RS08845	COG1846	Transcriptional regulator
VIBHAR_RS08850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VIBHAR_RS08875	COG1448	Aminotransferase
VIBHAR_RS08880	COG3437	response regulator, receiver
VIBHAR_RS08880	COG2770	Histidine kinase
VIBHAR_RS08895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VIBHAR_RS08910	COG0017	Asparaginyl-tRNA synthetase
VIBHAR_RS08920	COG0720	synthase
VIBHAR_RS08925	COG2197	response regulator
VIBHAR_RS08945	COG1760	l-serine dehydratase
VIBHAR_RS08950	COG0814	amino acid
VIBHAR_RS08970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VIBHAR_RS08985	COG3106	COG3106 Predicted ATPase
VIBHAR_RS09000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VIBHAR_RS09045	COG2433	Pfam Transposase IS66
VIBHAR_RS09070	COG4584	PFAM Integrase catalytic
VIBHAR_RS09075	COG1484	DNA-dependent DNA replication
VIBHAR_RS09080	COG2433	Pfam Transposase IS66
VIBHAR_RS09095	COG2433	Pfam Transposase IS66
VIBHAR_RS09130	COG0582	viral genome integration into host DNA
VIBHAR_RS09145	COG5532	Uncharacterized conserved protein (DUF2303)
VIBHAR_RS09160	COG3620	sequence-specific DNA binding
VIBHAR_RS09180	COG1802	Transcriptional regulator
VIBHAR_RS09180	COG4626	Terminase
VIBHAR_RS09200	COG1403	HNH endonuclease
VIBHAR_RS09255	COG3772	lysozyme
VIBHAR_RS09285	COG1030	water channel activity
VIBHAR_RS09435	COG3344	reverse transcriptase
VIBHAR_RS09475	COG3335	DDE superfamily endonuclease
VIBHAR_RS09490	COG2433	Pfam Transposase IS66
VIBHAR_RS09495	COG3335	DDE superfamily endonuclease
VIBHAR_RS09500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VIBHAR_RS09520	COG0471	metal ion transport
VIBHAR_RS09525	COG2949	membrane
VIBHAR_RS09535	COG1643	Atp-dependent helicase
VIBHAR_RS09615	COG2433	Pfam Transposase IS66
VIBHAR_RS09670	COG0247	lactate metabolic process
VIBHAR_RS09670	COG0277	FAD linked oxidase domain protein
VIBHAR_RS09715	COG2986	histidine ammonia-lyase
VIBHAR_RS09725	COG0010	Belongs to the arginase family
VIBHAR_RS09770	COG2433	Pfam Transposase IS66
VIBHAR_RS09790	COG0251	oxidation-reduction process
VIBHAR_RS09815	COG0072	phenylalanine-tRNA ligase activity
VIBHAR_RS09815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VIBHAR_RS09820	COG2433	Pfam Transposase IS66
VIBHAR_RS09835	COG1535	isochorismatase
VIBHAR_RS09835	COG3433	isochorismatase activity
VIBHAR_RS09840	COG1132	(ABC) transporter
VIBHAR_RS09845	COG1132	(ABC) transporter
VIBHAR_RS09845	COG2375	cellular response to nickel ion
VIBHAR_RS09855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VIBHAR_RS09875	COG4774	siderophore transport
VIBHAR_RS09880	COG4607	ABC-type enterochelin transport system periplasmic component
VIBHAR_RS09885	COG4605	iron ion homeostasis
VIBHAR_RS09890	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VIBHAR_RS09935	COG1346	cytolysis
VIBHAR_RS09945	COG2925	Exonuclease
VIBHAR_RS09955	COG1823	symporter activity
VIBHAR_RS09960	COG0702	epimerase
VIBHAR_RS09975	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VIBHAR_RS09985	COG2062	phosphohistidine phosphatase, SixA
VIBHAR_RS10000	COG4139	cobalamin transport
VIBHAR_RS10010	COG3335	DDE superfamily endonuclease
VIBHAR_RS10035	COG0583	DNA-binding transcription factor activity
VIBHAR_RS10050	COG2433	Pfam Transposase IS66
VIBHAR_RS10060	COG1451	nucleotide metabolic process
VIBHAR_RS10110	COG3335	DDE superfamily endonuclease
VIBHAR_RS10180	COG3335	DDE superfamily endonuclease
VIBHAR_RS10195	COG2195	Cleaves the N-terminal amino acid of tripeptides
VIBHAR_RS10200	COG3335	DDE superfamily endonuclease
VIBHAR_RS10215	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VIBHAR_RS10225	COG0625	glutathione transferase activity
VIBHAR_RS10285	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
VIBHAR_RS10305	COG0668	transmembrane transport
VIBHAR_RS10310	COG3247	response to pH
VIBHAR_RS10325	COG1846	Transcriptional regulator
VIBHAR_RS10350	COG0784	Response regulator, receiver
VIBHAR_RS10350	COG2205	protein histidine kinase activity
VIBHAR_RS10355	COG0110	maltose O-acetyltransferase activity
VIBHAR_RS10375	COG4999	Histidine kinase
VIBHAR_RS10375	COG3850	Histidine kinase
VIBHAR_RS10375	COG2205	protein histidine kinase activity
VIBHAR_RS10375	COG3437	response regulator, receiver
VIBHAR_RS10380	COG3300	MHYT domain
VIBHAR_RS10380	COG5001	Diguanylate cyclase
VIBHAR_RS10405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VIBHAR_RS10410	COG1215	transferase activity, transferring glycosyl groups
VIBHAR_RS10415	COG0438	transferase activity, transferring glycosyl groups
VIBHAR_RS10445	COG0438	transferase activity, transferring glycosyl groups
VIBHAR_RS10450	COG0438	transferase activity, transferring glycosyl groups
VIBHAR_RS10455	COG2204	response regulator
VIBHAR_RS10475	COG2885	chlorophyll binding
VIBHAR_RS10495	COG0534	Mate efflux family protein
VIBHAR_RS10500	COG0307	riboflavin synthase, alpha
VIBHAR_RS10510	COG3001	Fructosamine kinase
VIBHAR_RS10515	COG2201	protein-glutamate methylesterase activity
VIBHAR_RS10520	COG3706	GGDEF domain
VIBHAR_RS10530	COG0791	NLP P60 protein
VIBHAR_RS10535	COG0840	transmembrane signaling receptor activity
VIBHAR_RS10550	COG3344	reverse transcriptase
VIBHAR_RS10590	COG3148	PFAM DTW domain containing protein
VIBHAR_RS10595	COG1940	carbohydrate kinase activity
VIBHAR_RS10610	COG0303	'Molybdopterin
VIBHAR_RS10620	COG3842	ATPase activity
VIBHAR_RS10625	COG4662	Binding-protein-dependent transport system inner membrane component
VIBHAR_RS10635	COG2204	response regulator
VIBHAR_RS10640	COG4191	Histidine kinase
VIBHAR_RS10655	COG0488	(ABC) transporter
VIBHAR_RS10665	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VIBHAR_RS10685	COG3381	protein complex oligomerization
VIBHAR_RS10695	COG0243	molybdopterin cofactor binding
VIBHAR_RS10695	COG3383	formate dehydrogenase (NAD+) activity
VIBHAR_RS10700	COG0437	4 iron, 4 sulfur cluster binding
VIBHAR_RS10720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VIBHAR_RS10725	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VIBHAR_RS10735	COG1177	transmembrane transport
VIBHAR_RS10745	COG3842	ATPase activity
VIBHAR_RS10770	COG0589	response to stress
VIBHAR_RS10775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VIBHAR_RS10790	COG2217	Heavy metal translocating P-type atpase
VIBHAR_RS10800	COG2010	Cytochrome c
VIBHAR_RS10815	COG3278	Belongs to the heme-copper respiratory oxidase family
VIBHAR_RS10830	COG0784	Response regulator, receiver
VIBHAR_RS10830	COG2205	protein histidine kinase activity
VIBHAR_RS10945	COG1067	ATP-dependent peptidase activity
VIBHAR_RS10965	COG0488	(ABC) transporter
VIBHAR_RS10995	COG1484	DNA-dependent DNA replication
VIBHAR_RS11005	COG2902	Dehydrogenase
VIBHAR_RS11015	COG0308	aminopeptidase N
VIBHAR_RS11030	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VIBHAR_RS11035	COG1956	GAF domain-containing protein
VIBHAR_RS11040	COG1132	(ABC) transporter
VIBHAR_RS11045	COG2995	paraquat-inducible protein a
VIBHAR_RS11050	COG3008	intermembrane lipid transfer
VIBHAR_RS11075	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VIBHAR_RS11090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VIBHAR_RS11095	COG4597	amino acid ABC transporter
VIBHAR_RS11100	COG0765	amino acid transport
VIBHAR_RS11105	COG1126	abc transporter atp-binding protein
VIBHAR_RS11110	COG0670	Belongs to the BI1 family
VIBHAR_RS11115	COG2920	part of a sulfur-relay system
VIBHAR_RS11120	COG1254	Belongs to the acylphosphatase family
VIBHAR_RS11165	COG2433	Pfam Transposase IS66
VIBHAR_RS11190	COG3706	GGDEF domain
VIBHAR_RS11200	COG0602	queuosine metabolic process
VIBHAR_RS11205	COG0561	phosphatase activity
VIBHAR_RS11225	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
VIBHAR_RS11240	COG2828	Protein conserved in bacteria
VIBHAR_RS11250	COG0372	Belongs to the citrate synthase family
VIBHAR_RS11255	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VIBHAR_RS11270	COG2433	Pfam Transposase IS66
VIBHAR_RS11295	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VIBHAR_RS11315	COG2433	Pfam Transposase IS66
VIBHAR_RS11350	COG0730	response to heat
VIBHAR_RS11355	COG0840	transmembrane signaling receptor activity
VIBHAR_RS11360	COG2358	TRAP transporter, solute receptor (TAXI family
VIBHAR_RS11365	COG1012	belongs to the aldehyde dehydrogenase family
VIBHAR_RS11370	COG3284	Transcriptional regulator
VIBHAR_RS11385	COG3344	reverse transcriptase
VIBHAR_RS11390	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VIBHAR_RS11395	COG0363	glucosamine-6-phosphate deaminase activity
VIBHAR_RS11400	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VIBHAR_RS11405	COG4565	transcriptional regulatory protein
VIBHAR_RS11410	COG3290	protein histidine kinase activity
VIBHAR_RS11430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VIBHAR_RS11465	COG2433	Pfam Transposase IS66
VIBHAR_RS11495	COG1404	Belongs to the peptidase S8 family
VIBHAR_RS11500	COG1858	cytochrome C peroxidase
VIBHAR_RS11510	COG0527	aspartate kinase activity
VIBHAR_RS11520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VIBHAR_RS11525	COG0456	acetyltransferase
VIBHAR_RS11530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VIBHAR_RS11540	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
VIBHAR_RS11550	COG0215	cysteine-tRNA ligase activity
VIBHAR_RS11565	COG3335	DDE superfamily endonuclease
VIBHAR_RS11570	COG1368	sulfuric ester hydrolase activity
VIBHAR_RS11595	COG1115	amino acid carrier protein
VIBHAR_RS11630	COG1280	lysine exporter protein (LysE YggA)
VIBHAR_RS11635	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VIBHAR_RS11660	COG1560	Kdo2-lipid A biosynthetic process
VIBHAR_RS11665	COG1280	lysine exporter protein (LysE YggA)
VIBHAR_RS11670	COG0531	amino acid
VIBHAR_RS11695	COG3344	reverse transcriptase
VIBHAR_RS11705	COG3385	transposase activity
VIBHAR_RS11710	COG3063	Type IV pilus biogenesis stability protein PilW
VIBHAR_RS11745	COG1643	Atp-dependent helicase
VIBHAR_RS11750	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
VIBHAR_RS11765	COG3302	dmso reductase anchor subunit
VIBHAR_RS11770	COG0437	4 iron, 4 sulfur cluster binding
VIBHAR_RS11775	COG0243	molybdopterin cofactor binding
VIBHAR_RS11785	COG3227	Zinc metalloprotease (Elastase)
VIBHAR_RS11825	COG3706	GGDEF domain
VIBHAR_RS11835	COG0443	Heat shock 70 kDa protein
VIBHAR_RS11840	COG0443	Heat shock 70 kDa protein
VIBHAR_RS11855	COG2165	general secretion pathway protein
VIBHAR_RS11860	COG1132	(ABC) transporter
VIBHAR_RS11865	COG1132	(ABC) transporter
VIBHAR_RS11885	COG0814	amino acid
VIBHAR_RS11890	COG1454	alcohol dehydrogenase
VIBHAR_RS11895	COG4221	oxidoreductase activity
VIBHAR_RS11910	COG0861	Integral membrane protein TerC family
VIBHAR_RS11920	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VIBHAR_RS11925	COG1328	CTP reductase activity
VIBHAR_RS11930	COG1280	lysine exporter protein (LysE YggA)
VIBHAR_RS11960	COG3335	DDE superfamily endonuclease
VIBHAR_RS11975	COG0596	Alpha beta hydrolase
VIBHAR_RS11990	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VIBHAR_RS12000	COG1609	Transcriptional regulator
VIBHAR_RS12015	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VIBHAR_RS12015	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VIBHAR_RS12030	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VIBHAR_RS12035	COG3385	transposase activity
VIBHAR_RS12055	COG3340	Belongs to the peptidase S51 family
VIBHAR_RS12075	COG2433	Pfam Transposase IS66
VIBHAR_RS12120	COG3344	reverse transcriptase
VIBHAR_RS12150	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS12200	COG3335	DDE superfamily endonuclease
VIBHAR_RS12205	COG0492	ferredoxin-NADP+ reductase activity
VIBHAR_RS12210	COG4988	ABC transporter
VIBHAR_RS12215	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VIBHAR_RS12230	COG3293	Transposase
VIBHAR_RS12235	COG2200	EAL domain
VIBHAR_RS12245	COG3293	Transposase
VIBHAR_RS12265	COG5001	Diguanylate cyclase
VIBHAR_RS12280	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VIBHAR_RS12290	COG4191	Histidine kinase
VIBHAR_RS12290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VIBHAR_RS12305	COG3070	regulator of competence-specific genes
VIBHAR_RS12315	COG2431	L-lysine efflux transmembrane transporter activity
VIBHAR_RS12325	COG0076	glutamate decarboxylase activity
VIBHAR_RS12330	COG1737	Transcriptional regulator
VIBHAR_RS12340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VIBHAR_RS12350	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VIBHAR_RS12355	COG1960	acyl-CoA dehydrogenase activity
VIBHAR_RS12385	COG2433	Pfam Transposase IS66
VIBHAR_RS12410	COG4181	ATPase activity
VIBHAR_RS12415	COG0534	Mate efflux family protein
VIBHAR_RS12420	COG0702	epimerase
VIBHAR_RS12425	COG3344	reverse transcriptase
VIBHAR_RS12435	COG2814	Major facilitator Superfamily
VIBHAR_RS12440	COG1187	pseudouridine synthase activity
VIBHAR_RS12445	COG1061	Type III restriction enzyme res subunit
VIBHAR_RS12500	COG3313	Fe-S protein
VIBHAR_RS12510	COG0659	secondary active sulfate transmembrane transporter activity
VIBHAR_RS12545	COG0398	Pfam SNARE associated Golgi protein
VIBHAR_RS12550	COG4134	Bacterial extracellular solute-binding protein
VIBHAR_RS12555	COG4135	transport system, permease component
VIBHAR_RS12560	COG4136	ATPase activity
VIBHAR_RS12565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VIBHAR_RS12575	COG2814	Major facilitator Superfamily
VIBHAR_RS12585	COG3604	Transcriptional regulator
VIBHAR_RS12590	COG1151	hydroxylamine reductase activity
VIBHAR_RS12595	COG3335	DDE superfamily endonuclease
VIBHAR_RS12605	COG0564	pseudouridine synthase activity
VIBHAR_RS12615	COG0733	neurotransmitter:sodium symporter activity
VIBHAR_RS12625	COG0626	cystathionine gamma-synthase activity
VIBHAR_RS12630	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VIBHAR_RS12640	COG3335	DDE superfamily endonuclease
VIBHAR_RS12655	COG3335	DDE superfamily endonuclease
VIBHAR_RS12675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VIBHAR_RS12690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VIBHAR_RS12695	COG3108	Peptidase M15
VIBHAR_RS12700	COG2989	Protein conserved in bacteria
VIBHAR_RS12735	COG4235	cytochrome complex assembly
VIBHAR_RS12735	COG3088	subunit of a heme lyase
VIBHAR_RS12745	COG1138	Cytochrome C-type biogenesis protein
VIBHAR_RS12750	COG3301	Polysulphide reductase, NrfD
VIBHAR_RS12765	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
VIBHAR_RS12790	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VIBHAR_RS12795	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VIBHAR_RS12805	COG1546	Belongs to the CinA family
VIBHAR_RS12805	COG1058	Belongs to the CinA family
VIBHAR_RS12820	COG0019	diaminopimelate decarboxylase activity
VIBHAR_RS12860	COG0322	excinuclease ABC activity
VIBHAR_RS12865	COG2197	response regulator
VIBHAR_RS12870	COG0417	DNA replication proofreading
VIBHAR_RS12890	COG1187	pseudouridine synthase activity
VIBHAR_RS12900	COG0009	L-threonylcarbamoyladenylate synthase
VIBHAR_RS12905	COG0613	PHP domain protein
VIBHAR_RS12915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VIBHAR_RS12920	COG0512	Glutamine amidotransferase of anthranilate synthase
VIBHAR_RS12930	COG0135	phosphoribosylanthranilate isomerase activity
VIBHAR_RS12930	COG0134	indole-3-glycerol-phosphate synthase activity
VIBHAR_RS12940	COG0159	tryptophan synthase activity
VIBHAR_RS12945	COG1301	dicarboxylic acid transport
VIBHAR_RS12975	COG2350	Protein conserved in bacteria
VIBHAR_RS13005	COG5001	Diguanylate cyclase
VIBHAR_RS13005	COG1716	ATPase activity
VIBHAR_RS13010	COG1032	radical SAM domain protein
VIBHAR_RS13030	COG0446	pyridine nucleotide-disulphide oxidoreductase
VIBHAR_RS13040	COG0251	oxidation-reduction process
VIBHAR_RS13045	COG2964	Protein conserved in bacteria
VIBHAR_RS13050	COG2175	clavaminate synthase activity
VIBHAR_RS13055	COG0840	transmembrane signaling receptor activity
VIBHAR_RS13065	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
VIBHAR_RS13070	COG0463	Glycosyl transferase, family 2
VIBHAR_RS13075	COG0745	RESPONSE REGULATOR receiver
VIBHAR_RS13080	COG5002	protein histidine kinase activity
VIBHAR_RS13080	COG3850	Histidine kinase
VIBHAR_RS13110	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS13155	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS13220	COG2176	DNA-directed DNA polymerase activity
VIBHAR_RS13235	COG1136	(ABC) transporter
VIBHAR_RS13235	COG0577	efflux transmembrane transporter activity
VIBHAR_RS13255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VIBHAR_RS13280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VIBHAR_RS13295	COG4232	protein-disulfide reductase activity
VIBHAR_RS13310	COG2995	paraquat-inducible protein a
VIBHAR_RS13315	COG3008	intermembrane lipid transfer
VIBHAR_RS13315	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VIBHAR_RS13320	COG3009	Protein conserved in bacteria
VIBHAR_RS13335	COG4166	transmembrane transport
VIBHAR_RS13345	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VIBHAR_RS13350	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VIBHAR_RS13360	COG0539	negative regulation of cytoplasmic translation
VIBHAR_RS13370	COG0616	signal peptide processing
VIBHAR_RS13375	COG1028	Short-chain dehydrogenase reductase Sdr
VIBHAR_RS13395	COG0835	chemotaxis
VIBHAR_RS13395	COG0784	Response regulator, receiver
VIBHAR_RS13400	COG1940	carbohydrate kinase activity
VIBHAR_RS13415	COG2433	Pfam Transposase IS66
VIBHAR_RS13445	COG2272	Belongs to the type-B carboxylesterase lipase family
VIBHAR_RS13495	COG2433	Pfam Transposase IS66
VIBHAR_RS13510	COG4667	esterase of the alpha-beta hydrolase superfamily
VIBHAR_RS13530	COG0733	neurotransmitter:sodium symporter activity
VIBHAR_RS13535	COG3385	transposase activity
VIBHAR_RS13545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VIBHAR_RS13545	COG1263	PTS System
VIBHAR_RS13550	COG0084	hydrolase, TatD family'
VIBHAR_RS13565	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VIBHAR_RS13595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VIBHAR_RS13610	COG1399	metal-binding, possibly nucleic acid-binding protein
VIBHAR_RS13615	COG0424	maF-like protein
VIBHAR_RS13620	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS13625	COG0564	pseudouridine synthase activity
VIBHAR_RS13630	COG1530	ribonuclease E activity
VIBHAR_RS13640	COG0659	secondary active sulfate transmembrane transporter activity
VIBHAR_RS13645	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VIBHAR_RS13650	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VIBHAR_RS13680	COG2186	Transcriptional regulator
VIBHAR_RS13690	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VIBHAR_RS13695	COG0653	protein targeting
VIBHAR_RS13700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VIBHAR_RS13715	COG1122	ATPase activity
VIBHAR_RS13720	COG4120	Belongs to the binding-protein-dependent transport system permease family
VIBHAR_RS13740	COG0857	belongs to the CobB CobQ family
VIBHAR_RS13740	COG0280	phosphate acetyltransferase
VIBHAR_RS13745	COG0435	Glutathione S-transferase
VIBHAR_RS13755	COG0444	Belongs to the ABC transporter superfamily
VIBHAR_RS13760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VIBHAR_RS13765	COG0601	transmembrane transport
VIBHAR_RS13775	COG0314	molybdopterin synthase activity
VIBHAR_RS13780	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VIBHAR_RS13790	COG0521	Mo-molybdopterin cofactor biosynthetic process
VIBHAR_RS13795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VIBHAR_RS13800	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VIBHAR_RS13805	COG2433	Pfam Transposase IS66
VIBHAR_RS13830	COG0556	nucleotide-excision repair
VIBHAR_RS13840	COG1882	Formate acetyltransferase
VIBHAR_RS13855	COG4656	Part of a membrane complex involved in electron transport
VIBHAR_RS13860	COG4658	electron transport chain
VIBHAR_RS13865	COG4659	FMN binding
VIBHAR_RS13870	COG4660	Part of a membrane complex involved in electron transport
VIBHAR_RS13875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VIBHAR_RS13890	COG3385	transposase activity
VIBHAR_RS13895	COG3344	reverse transcriptase
VIBHAR_RS13910	COG2433	Pfam Transposase IS66
VIBHAR_RS13935	COG0840	transmembrane signaling receptor activity
VIBHAR_RS13940	COG3344	reverse transcriptase
VIBHAR_RS13945	COG0346	lactoylglutathione lyase activity
VIBHAR_RS13955	COG2885	chlorophyll binding
VIBHAR_RS13965	COG2056	Na+-H+ antiporter family
VIBHAR_RS14000	COG3451	type IV secretory pathway VirB4
VIBHAR_RS14010	COG2433	Pfam Transposase IS66
VIBHAR_RS14045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VIBHAR_RS14055	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VIBHAR_RS14070	COG1028	Short-chain dehydrogenase reductase Sdr
VIBHAR_RS14075	COG3344	reverse transcriptase
VIBHAR_RS14080	COG1454	alcohol dehydrogenase
VIBHAR_RS14080	COG1012	belongs to the aldehyde dehydrogenase family
VIBHAR_RS14085	COG2095	MarC family integral membrane protein
VIBHAR_RS14090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VIBHAR_RS14095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VIBHAR_RS14100	COG1757	Na H antiporter
VIBHAR_RS14115	COG3385	transposase activity
VIBHAR_RS14130	COG3083	sulfuric ester hydrolase activity
VIBHAR_RS14140	COG3344	reverse transcriptase
VIBHAR_RS14145	COG3385	transposase activity
VIBHAR_RS14155	COG4269	membrane
VIBHAR_RS14165	COG0123	including yeast histone deacetylase and acetoin utilization protein
VIBHAR_RS14190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VIBHAR_RS14195	COG0778	Nitroreductase
VIBHAR_RS14200	COG1902	pentaerythritol trinitrate reductase activity
VIBHAR_RS14200	COG0446	pyridine nucleotide-disulphide oxidoreductase
VIBHAR_RS14205	COG0616	signal peptide processing
VIBHAR_RS14210	COG0252	asparaginase activity
VIBHAR_RS14215	COG3139	Protein of unknown function (DUF1315)
VIBHAR_RS14225	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VIBHAR_RS14230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VIBHAR_RS14250	COG2226	methyltransferase
VIBHAR_RS14270	COG1785	Belongs to the alkaline phosphatase family
VIBHAR_RS14285	COG0346	lactoylglutathione lyase activity
VIBHAR_RS14295	COG0668	transmembrane transport
VIBHAR_RS14300	COG0076	glutamate decarboxylase activity
VIBHAR_RS14305	COG2985	domain, Protein
VIBHAR_RS14310	COG2261	transglycosylase associated protein
VIBHAR_RS14365	COG2964	Protein conserved in bacteria
VIBHAR_RS14375	COG0251	oxidation-reduction process
VIBHAR_RS14385	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VIBHAR_RS14390	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VIBHAR_RS14400	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
VIBHAR_RS14410	COG2832	Protein of unknown function (DUF454)
VIBHAR_RS14420	COG0745	RESPONSE REGULATOR receiver
VIBHAR_RS14425	COG0583	DNA-binding transcription factor activity
VIBHAR_RS14435	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VIBHAR_RS14440	COG1286	toxin biosynthetic process
VIBHAR_RS14445	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VIBHAR_RS14450	COG0285	dihydrofolate synthase activity
VIBHAR_RS14475	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VIBHAR_RS14480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VIBHAR_RS14485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VIBHAR_RS14510	COG3101	peptidyl-lysine hydroxylation
VIBHAR_RS14515	COG2860	membrane
VIBHAR_RS14530	COG2890	protein-(glutamine-N5) methyltransferase activity
VIBHAR_RS14540	COG2062	phosphohistidine phosphatase, SixA
VIBHAR_RS14550	COG3344	reverse transcriptase
VIBHAR_RS14560	COG0183	Belongs to the thiolase family
VIBHAR_RS14575	COG2067	long-chain fatty acid transport protein
VIBHAR_RS14580	COG2067	long-chain fatty acid transport protein
VIBHAR_RS14585	COG2853	Lipoprotein
VIBHAR_RS14590	COG4235	cytochrome complex assembly
VIBHAR_RS14590	COG3088	subunit of a heme lyase
VIBHAR_RS14600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VIBHAR_RS14605	COG1138	Cytochrome C-type biogenesis protein
VIBHAR_RS14620	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VIBHAR_RS14625	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VIBHAR_RS14630	COG4133	protoheme IX ABC transporter activity
VIBHAR_RS14640	COG0835	chemotaxis
VIBHAR_RS14650	COG1192	Involved in chromosome partitioning
VIBHAR_RS14655	COG2201	protein-glutamate methylesterase activity
VIBHAR_RS14660	COG2198	Histidine kinase
VIBHAR_RS14660	COG0784	Response regulator, receiver
VIBHAR_RS14660	COG0643	Histidine kinase
VIBHAR_RS14665	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VIBHAR_RS14700	COG1684	flagellar biosynthetic protein fliR
VIBHAR_RS14705	COG1987	bacterial-type flagellum assembly
VIBHAR_RS14760	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VIBHAR_RS14770	COG1677	Flagellar hook-basal body complex protein FliE
VIBHAR_RS14790	COG1516	flagellar protein fliS
VIBHAR_RS14800	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VIBHAR_RS14805	COG1334	flagellar protein FlaG
VIBHAR_RS14810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VIBHAR_RS14820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VIBHAR_RS14825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VIBHAR_RS14835	COG2837	iron assimilation
VIBHAR_RS14860	COG1393	Belongs to the ArsC family
VIBHAR_RS14880	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VIBHAR_RS14885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VIBHAR_RS14890	COG2716	regulation of RNA biosynthetic process
VIBHAR_RS14895	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VIBHAR_RS14915	COG4783	chaperone-mediated protein folding
VIBHAR_RS14920	COG1393	Belongs to the ArsC family
VIBHAR_RS14940	COG2233	PERMEase
VIBHAR_RS14945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VIBHAR_RS14955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VIBHAR_RS14960	COG0121	glutamine amidotransferase
VIBHAR_RS14965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VIBHAR_RS14970	COG1960	acyl-CoA dehydrogenase activity
VIBHAR_RS14995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VIBHAR_RS15005	COG2226	methyltransferase
VIBHAR_RS15015	COG1388	LysM domain
VIBHAR_RS15015	COG0741	lytic transglycosylase activity
VIBHAR_RS15030	COG0347	Belongs to the P(II) protein family
VIBHAR_RS15050	COG0587	DNA-directed DNA polymerase activity
VIBHAR_RS15075	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VIBHAR_RS15080	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VIBHAR_RS15090	COG0750	zinc metalloprotease
VIBHAR_RS15100	COG0575	Belongs to the CDS family
VIBHAR_RS15105	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VIBHAR_RS15130	COG0024	Methionine aminopeptidase
VIBHAR_RS15145	COG0564	pseudouridine synthase activity
VIBHAR_RS15150	COG3098	single-species biofilm formation
VIBHAR_RS15180	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VIBHAR_RS15190	COG1720	tRNA m6t6A37 methyltransferase activity
VIBHAR_RS15215	COG0733	neurotransmitter:sodium symporter activity
VIBHAR_RS15225	COG3385	transposase activity
VIBHAR_RS15235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VIBHAR_RS15240	COG0514	ATP-dependent DNA helicase (RecQ)
VIBHAR_RS15245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VIBHAR_RS15255	COG3344	reverse transcriptase
VIBHAR_RS15270	COG1477	protein flavinylation
VIBHAR_RS15305	COG0271	Belongs to the BolA IbaG family
VIBHAR_RS15335	COG1595	DNA-templated transcription, initiation
VIBHAR_RS15355	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VIBHAR_RS15360	COG0693	protein deglycase activity
VIBHAR_RS15365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VIBHAR_RS15370	COG2166	iron-sulfur cluster assembly
VIBHAR_RS15375	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VIBHAR_RS15380	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VIBHAR_RS15390	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VIBHAR_RS15390	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VIBHAR_RS15400	COG3385	transposase activity
VIBHAR_RS15415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VIBHAR_RS15420	COG1074	ATP-dependent DNA helicase activity
VIBHAR_RS15425	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VIBHAR_RS15445	COG3141	response to X-ray
VIBHAR_RS15465	COG2171	N-acyltransferase activity
VIBHAR_RS15470	COG0584	glycerophosphoryl diester phosphodiesterase
VIBHAR_RS15475	COG2271	Major facilitator Superfamily
VIBHAR_RS15480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VIBHAR_RS15490	COG1349	DNA-binding transcription factor activity
VIBHAR_RS15495	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VIBHAR_RS15520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VIBHAR_RS15535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VIBHAR_RS15535	COG1263	PTS System
VIBHAR_RS15540	COG1609	Transcriptional regulator
VIBHAR_RS15545	COG2017	converts alpha-aldose to the beta-anomer
VIBHAR_RS15560	COG1085	galactose-1-phosphate uridylyltransferase
VIBHAR_RS15565	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS15570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VIBHAR_RS15580	COG0768	penicillin binding
VIBHAR_RS15585	COG1609	Transcriptional regulator
VIBHAR_RS15595	COG2731	YhcH YjgK YiaL family protein
VIBHAR_RS15600	COG0531	amino acid
VIBHAR_RS15605	COG0583	DNA-binding transcription factor activity
VIBHAR_RS15665	COG4964	Belongs to the GSP D family
VIBHAR_RS15685	COG2433	Pfam Transposase IS66
VIBHAR_RS15700	COG0583	DNA-binding transcription factor activity
VIBHAR_RS15705	COG0741	lytic transglycosylase activity
VIBHAR_RS15710	COG1022	Amp-dependent synthetase and ligase
VIBHAR_RS15740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VIBHAR_RS15745	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VIBHAR_RS15755	COG0560	Phosphoserine phosphatase
VIBHAR_RS15765	COG0813	purine-nucleoside phosphorylase activity
VIBHAR_RS15775	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VIBHAR_RS15785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VIBHAR_RS15790	COG0084	hydrolase, TatD family'
VIBHAR_RS15815	COG3153	acetyltransferase
VIBHAR_RS15820	COG3154	lipid carrier protein
VIBHAR_RS15830	COG0826	peptidase U32
VIBHAR_RS15835	COG0826	peptidase U32
VIBHAR_RS15840	COG0534	Mate efflux family protein
VIBHAR_RS15860	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VIBHAR_RS15880	COG0195	Participates in both transcription termination and antitermination
VIBHAR_RS15900	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VIBHAR_RS15915	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VIBHAR_RS15920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VIBHAR_RS15930	COG1534	Rna-binding protein
VIBHAR_RS15935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VIBHAR_RS15940	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VIBHAR_RS15945	COG2027	D-alanyl-D-alanine carboxypeptidase
VIBHAR_RS15960	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VIBHAR_RS15965	COG0739	heme binding
VIBHAR_RS15990	COG0628	permease
VIBHAR_RS16000	COG2198	Histidine kinase
VIBHAR_RS16000	COG2205	protein histidine kinase activity
VIBHAR_RS16000	COG0784	Response regulator, receiver
VIBHAR_RS16000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VIBHAR_RS16005	COG0747	negative chemotaxis
VIBHAR_RS16015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VIBHAR_RS16020	COG0444	Belongs to the ABC transporter superfamily
VIBHAR_RS16025	COG4608	Belongs to the ABC transporter superfamily
VIBHAR_RS16035	COG2971	BadF BadG BcrA BcrD
VIBHAR_RS16050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VIBHAR_RS16055	COG3842	ATPase activity
VIBHAR_RS16065	COG1840	ABC-type Fe3 transport system, periplasmic component
VIBHAR_RS16070	COG0004	ammonium transporteR
VIBHAR_RS16085	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS16090	COG1049	propionate catabolic process, 2-methylcitrate cycle
VIBHAR_RS16095	COG1752	Esterase of the alpha-beta hydrolase superfamily
VIBHAR_RS16100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VIBHAR_RS16105	COG1643	Atp-dependent helicase
VIBHAR_RS16120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VIBHAR_RS16130	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VIBHAR_RS16145	COG1560	Kdo2-lipid A biosynthetic process
VIBHAR_RS16155	COG0842	Transport permease protein
VIBHAR_RS16160	COG1131	(ABC) transporter
VIBHAR_RS16165	COG0659	secondary active sulfate transmembrane transporter activity
VIBHAR_RS16170	COG0288	reversible hydration of carbon dioxide
VIBHAR_RS16190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VIBHAR_RS16195	COG0508	dehydrogenase complex catalyzes the overall conversion of
VIBHAR_RS16200	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VIBHAR_RS16205	COG2186	Transcriptional regulator
VIBHAR_RS16225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VIBHAR_RS16230	COG1459	type II secretion system
VIBHAR_RS16240	COG0237	dephospho-CoA kinase activity
VIBHAR_RS16245	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VIBHAR_RS16250	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
VIBHAR_RS16255	COG3547	Transposase (IS116 IS110 IS902 family)
VIBHAR_RS16260	COG3344	reverse transcriptase
VIBHAR_RS16285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VIBHAR_RS16290	COG4137	Cytochrome C assembly protein
VIBHAR_RS16295	COG4536	flavin adenine dinucleotide binding
VIBHAR_RS16315	COG0612	Peptidase, M16
VIBHAR_RS16320	COG1238	metal cluster binding
VIBHAR_RS16330	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VIBHAR_RS16335	COG5016	pyruvate
VIBHAR_RS16335	COG0511	ligase activity, forming carbon-carbon bonds
VIBHAR_RS16340	COG3630	sodium ion export across plasma membrane
VIBHAR_RS16425	COG0527	aspartate kinase activity
VIBHAR_RS16440	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VIBHAR_RS16445	COG1546	Belongs to the CinA family
VIBHAR_RS16455	COG3385	transposase activity
VIBHAR_RS16460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VIBHAR_RS16490	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VIBHAR_RS16500	COG0148	phosphopyruvate hydratase activity
VIBHAR_RS16510	COG3956	TIGRFAM MazG family protein
VIBHAR_RS16515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VIBHAR_RS16530	COG3385	transposase activity
VIBHAR_RS16540	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VIBHAR_RS16545	COG1381	Involved in DNA repair and RecF pathway recombination
VIBHAR_RS16550	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VIBHAR_RS16570	COG3086	response to oxidative stress
VIBHAR_RS16585	COG1595	DNA-templated transcription, initiation
VIBHAR_RS16590	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VIBHAR_RS16600	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VIBHAR_RS16620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VIBHAR_RS16625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VIBHAR_RS16635	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VIBHAR_RS16640	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VIBHAR_RS16650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VIBHAR_RS16660	COG0583	DNA-binding transcription factor activity
VIBHAR_RS16675	COG0668	transmembrane transport
VIBHAR_RS16680	COG0191	fructose-bisphosphate aldolase activity
VIBHAR_RS16700	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VIBHAR_RS16720	COG2356	endonuclease I
VIBHAR_RS16725	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VIBHAR_RS16730	COG0189	ligase activity
VIBHAR_RS16735	COG1678	Uncharacterized ACR, COG1678
VIBHAR_RS16740	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VIBHAR_RS16755	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VIBHAR_RS16760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VIBHAR_RS16765	COG0762	integral membrane protein
VIBHAR_RS16780	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VIBHAR_RS16785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VIBHAR_RS16900	COG1012	belongs to the aldehyde dehydrogenase family
VIBHAR_RS16945	COG3437	response regulator, receiver
VIBHAR_RS16950	COG1609	Transcriptional regulator
VIBHAR_RS16960	COG1486	melibiose metabolic process
VIBHAR_RS16965	COG1447	Phosphotransferase system cellobiose-specific component IIA
VIBHAR_RS16975	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VIBHAR_RS16980	COG0726	polysaccharide deacetylase
VIBHAR_RS17000	COG1028	Short-chain dehydrogenase reductase Sdr
VIBHAR_RS17010	COG0795	lipopolysaccharide-transporting ATPase activity
VIBHAR_RS17015	COG0795	lipopolysaccharide-transporting ATPase activity
VIBHAR_RS17025	COG2927	DNA polymerase III (CHI subunit)
VIBHAR_RS17030	COG0525	valine-tRNA ligase activity
VIBHAR_RS17040	COG0456	acetyltransferase
VIBHAR_RS17075	COG0251	oxidation-reduction process
VIBHAR_RS17080	COG3344	reverse transcriptase
VIBHAR_RS17085	COG0204	Acyl-transferase
VIBHAR_RS17095	COG5007	Belongs to the BolA IbaG family
VIBHAR_RS17105	COG2854	intermembrane phospholipid transfer
VIBHAR_RS17110	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VIBHAR_RS17115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VIBHAR_RS17120	COG1127	ABC transporter
VIBHAR_RS17130	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VIBHAR_RS17130	COG0517	IMP dehydrogenase activity
VIBHAR_RS17140	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VIBHAR_RS17145	COG1137	ATPase activity
VIBHAR_RS17155	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VIBHAR_RS17160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VIBHAR_RS17170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VIBHAR_RS17175	COG2239	Acts as a magnesium transporter
VIBHAR_RS17180	COG3344	reverse transcriptase
VIBHAR_RS17185	COG0312	modulator of DNA gyrase
VIBHAR_RS17195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VIBHAR_RS17200	COG0564	pseudouridine synthase activity
VIBHAR_RS17215	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VIBHAR_RS17220	COG0312	modulator of DNA gyrase
VIBHAR_RS17225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VIBHAR_RS17230	COG3164	Protein of unknown function
VIBHAR_RS17240	COG0424	maF-like protein
VIBHAR_RS17245	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VIBHAR_RS17250	COG1792	Involved in formation and maintenance of cell shape
VIBHAR_RS17255	COG1077	Cell shape determining protein MreB Mrl
VIBHAR_RS17275	COG2165	general secretion pathway protein
VIBHAR_RS17300	COG1459	type II secretion system
VIBHAR_RS17305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VIBHAR_RS17315	COG3409	Peptidoglycan-binding domain 1 protein
VIBHAR_RS17315	COG3267	Type II secretory pathway component ExeA
VIBHAR_RS17340	COG2200	EAL domain
VIBHAR_RS17340	COG2199	diguanylate cyclase activity
VIBHAR_RS17350	COG0629	single-stranded DNA binding
VIBHAR_RS17365	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VIBHAR_RS17375	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VIBHAR_RS17380	COG0527	aspartate kinase activity
VIBHAR_RS17385	COG1410	methionine synthase
VIBHAR_RS17385	COG0646	methionine synthase
VIBHAR_RS17400	COG3335	DDE superfamily endonuclease
VIBHAR_RS17440	COG2205	protein histidine kinase activity
VIBHAR_RS17440	COG0784	Response regulator, receiver
VIBHAR_RS17490	COG0735	belongs to the Fur family
VIBHAR_RS17775	COG0488	(ABC) transporter
VIBHAR_RS18090	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VIBHAR_RS18190	COG0439	Biotin carboxylase
VIBHAR_RS18695	COG0552	protein localization to endoplasmic reticulum
VIBHAR_RS18795	COG0561	phosphatase activity
VIBHAR_RS19085	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VIBHAR_RS19195	COG0569	domain protein
VIBHAR_RS19660	COG0129	dihydroxy-acid dehydratase activity
VIBHAR_RS19665	COG3265	gluconokinase activity
VIBHAR_RS20170	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VIBHAR_RS20235	COG2183	response to ionizing radiation
VIBHAR_RS20305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VIBHAR_RS20310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VIBHAR_RS20460	COG0463	Glycosyl transferase, family 2
VIBHAR_RS21305	COG3267	Type II secretory pathway component ExeA
VIBHAR_RS21305	COG3409	Peptidoglycan-binding domain 1 protein
VIBHAR_RS21320	COG0306	phosphate transporter
VIBHAR_RS21370	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VIBHAR_RS21635	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VIBHAR_RS21765	COG0784	Response regulator, receiver
VIBHAR_RS21765	COG2198	Histidine kinase
VIBHAR_RS21765	COG5002	protein histidine kinase activity
VIBHAR_RS21810	COG0083	homoserine kinase activity
VIBHAR_RS21985	COG0667	Aldo Keto reductase
VIBHAR_RS22030	COG0728	peptidoglycan biosynthetic process
VIBHAR_RS22225	COG3335	DDE superfamily endonuclease
VIBHAR_RS22265	COG0248	Ppx GppA phosphatase
VIBHAR_RS22275	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VIBHAR_RS23245	COG1702	phosphate starvation-inducible protein PhoH
VIBHAR_RS23455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VIBHAR_RS23665	COG1053	succinate dehydrogenase
VIBHAR_RS23750	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
VIBHAR_RS24230	COG4372	Transposase
VIBHAR_RS24395	COG1252	NADH dehydrogenase
VIBHAR_RS24425	COG4591	ABC-type transport system involved in lipoprotein release permease component
VIBHAR_RS24465	COG2766	serine protein kinase
VIBHAR_RS24500	COG1882	Formate acetyltransferase
VIBHAR_RS24600	COG0542	response to heat
VIBHAR_RS24705	COG0745	RESPONSE REGULATOR receiver
VIBHAR_RS24885	COG2433	Pfam Transposase IS66
VIBHAR_RS25215	COG1450	Type ii and iii secretion system protein
VIBHAR_RS25660	COG0402	S-adenosylhomocysteine deaminase activity
VIBHAR_RS25700	COG1674	ftsk spoiiie
VIBHAR_RS25995	COG4171	peptide transport system, permease
VIBHAR_RS26005	COG4168	peptide transport system, permease
VIBHAR_RS26015	COG4166	transmembrane transport
VIBHAR_RS26095	COG0840	transmembrane signaling receptor activity
VIBHAR_RS26425	COG1403	HNH endonuclease
VIBHAR_RS27570	COG0557	exoribonuclease II activity
VIBHAR_RS27775	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VIBHAR_RS27775	COG0165	Argininosuccinate lyase
VIBHAR_RS27870	COG0626	cystathionine gamma-synthase activity