locus-tag	class	description
C1N50_RS00010	COG0592	DNA-directed DNA polymerase activity
C1N50_RS00020	COG0187	DNA topoisomerase II activity
C1N50_RS00025	COG0071	Belongs to the small heat shock protein (HSP20) family
C1N50_RS00030	COG3977	Valine--pyruvate aminotransferase
C1N50_RS00045	COG2119	membrane
C1N50_RS00055	COG0425	Belongs to the sulfur carrier protein TusA family
C1N50_RS00070	COG0604	alcohol dehydrogenase
C1N50_RS00075	COG0183	Belongs to the thiolase family
C1N50_RS00085	COG1739	Uncharacterized protein family UPF0029
C1N50_RS00090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N50_RS00145	COG2132	Multicopper oxidase
C1N50_RS00165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C1N50_RS00170	COG2104	thiamine diphosphate biosynthetic process
C1N50_RS00185	COG0006	proline dipeptidase activity
C1N50_RS00185	COG0006	proline dipeptidase activity
C1N50_RS00195	COG2814	Major facilitator Superfamily
C1N50_RS00215	COG3220	belongs to the UPF0276 family
C1N50_RS00225	COG0210	DNA helicase
C1N50_RS00235	COG0405	Gamma-glutamyltransferase
C1N50_RS00240	COG1280	lysine exporter protein (LysE YggA)
C1N50_RS00260	COG2962	Rard protein
C1N50_RS00265	COG0514	ATP-dependent DNA helicase (RecQ)
C1N50_RS00280	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C1N50_RS00295	COG3118	belongs to the thioredoxin family
C1N50_RS00310	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C1N50_RS00315	COG0633	Ferredoxin
C1N50_RS00360	COG3071	HemY protein
C1N50_RS00365	COG2959	enzyme of heme biosynthesis
C1N50_RS00370	COG1587	Uroporphyrinogen-III synthase
C1N50_RS00380	COG3072	Adenylate cyclase
C1N50_RS00385	COG1965	Belongs to the frataxin family
C1N50_RS00395	COG0019	diaminopimelate decarboxylase activity
C1N50_RS00415	COG1011	Hydrolase
C1N50_RS00420	COG3287	FIST C domain
C1N50_RS00420	COG2200	EAL domain
C1N50_RS00420	COG2199	diguanylate cyclase activity
C1N50_RS00425	COG3148	PFAM DTW domain containing protein
C1N50_RS00440	COG0561	phosphatase activity
C1N50_RS00445	COG2267	carboxylic ester hydrolase activity
C1N50_RS00450	COG1280	lysine exporter protein (LysE YggA)
C1N50_RS00455	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C1N50_RS00460	COG0640	Transcriptional regulator
C1N50_RS00465	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C1N50_RS00520	COG2095	MarC family integral membrane protein
C1N50_RS00530	COG0742	ribosomal rna small subunit methyltransferase
C1N50_RS00535	COG0552	protein localization to endoplasmic reticulum
C1N50_RS00540	COG2884	Cell division ATP-binding protein ftsE
C1N50_RS00545	COG2177	Part of the ABC transporter FtsEX involved in
C1N50_RS00565	COG0705	Rhomboid family
C1N50_RS00570	COG1580	Controls the rotational direction of flagella during chemotaxis
C1N50_RS00575	COG3161	chorismate lyase activity
C1N50_RS00585	COG2937	Belongs to the GPAT DAPAT family
C1N50_RS00650	COG0534	Mate efflux family protein
C1N50_RS00655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1N50_RS00760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1N50_RS00770	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C1N50_RS00820	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C1N50_RS00825	COG0250	Participates in transcription elongation, termination and antitermination
C1N50_RS00840	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C1N50_RS00865	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
C1N50_RS00870	COG2816	NAD+ diphosphatase activity
C1N50_RS00890	COG1573	uracil-dna glycosylase
C1N50_RS00900	COG3068	Protein conserved in bacteria
C1N50_RS00905	COG1253	flavin adenine dinucleotide binding
C1N50_RS00920	COG0151	Belongs to the GarS family
C1N50_RS00930	COG0789	Transcriptional regulator
C1N50_RS00935	COG3710	Transcriptional regulator
C1N50_RS00945	COG0531	amino acid
C1N50_RS00950	COG1982	Orn Lys Arg decarboxylase major
C1N50_RS00995	COG2199	diguanylate cyclase activity
C1N50_RS01000	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C1N50_RS01005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1N50_RS01020	COG0439	Biotin carboxylase
C1N50_RS01025	COG0511	ligase activity, forming carbon-carbon bonds
C1N50_RS01030	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C1N50_RS01035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1N50_RS01050	COG2814	Major facilitator Superfamily
C1N50_RS01055	COG2198	Histidine kinase
C1N50_RS01055	COG0784	Response regulator, receiver
C1N50_RS01055	COG2205	protein histidine kinase activity
C1N50_RS01075	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C1N50_RS01085	COG2095	MarC family integral membrane protein
C1N50_RS01095	COG4232	protein-disulfide reductase activity
C1N50_RS01100	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C1N50_RS01105	COG1027	Aspartate ammonia-lyase
C1N50_RS01115	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C1N50_RS01125	COG2205	protein histidine kinase activity
C1N50_RS01130	COG0745	RESPONSE REGULATOR receiver
C1N50_RS01150	COG0534	Mate efflux family protein
C1N50_RS01175	COG1509	lysine 2,3-aminomutase activity
C1N50_RS01205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C1N50_RS01210	COG1053	succinate dehydrogenase
C1N50_RS01235	COG4942	peptidase
C1N50_RS01240	COG1045	serine acetyltransferase
C1N50_RS01250	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C1N50_RS01255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N50_RS01260	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C1N50_RS01270	COG0840	transmembrane signaling receptor activity
C1N50_RS01275	COG0471	metal ion transport
C1N50_RS01285	COG1162	GTPase activity
C1N50_RS01365	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C1N50_RS01370	COG0802	atpase or kinase
C1N50_RS01375	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1N50_RS01380	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C1N50_RS01395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C1N50_RS01400	COG0330	HflC and HflK could
C1N50_RS01405	COG0330	HflC and HflK could
C1N50_RS01410	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C1N50_RS01415	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C1N50_RS01425	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C1N50_RS01430	COG1017	nitric oxide dioxygenase activity
C1N50_RS01430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1N50_RS01440	COG0557	exoribonuclease II activity
C1N50_RS01445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1N50_RS01450	COG0546	phosphoglycolate phosphatase activity
C1N50_RS01470	COG0512	Glutamine amidotransferase of anthranilate synthase
C1N50_RS01475	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C1N50_RS01495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1N50_RS01500	COG3954	Phosphoribulokinase
C1N50_RS01510	COG0429	hydrolase of the alpha beta-hydrolase fold
C1N50_RS01520	COG0488	(ABC) transporter
C1N50_RS01530	COG2249	NAD(P)H dehydrogenase (quinone) activity
C1N50_RS01545	COG1047	Peptidyl-prolyl cis-trans
C1N50_RS01555	COG1446	asparaginase
C1N50_RS01570	COG0545	Peptidyl-prolyl cis-trans isomerase
C1N50_RS01575	COG2964	Protein conserved in bacteria
C1N50_RS01580	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C1N50_RS01585	COG2923	Belongs to the DsrF TusC family
C1N50_RS01590	COG2168	tRNA wobble position uridine thiolation
C1N50_RS01605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C1N50_RS01615	COG2906	2 iron, 2 sulfur cluster binding
C1N50_RS01625	COG0281	malic enzyme
C1N50_RS01635	COG0626	cystathionine gamma-synthase activity
C1N50_RS01640	COG0460	homoserine dehydrogenase
C1N50_RS01640	COG0527	aspartate kinase activity
C1N50_RS01645	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C1N50_RS01655	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C1N50_RS01665	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C1N50_RS01680	COG0165	Argininosuccinate lyase
C1N50_RS01680	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C1N50_RS01695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1N50_RS01700	COG0678	peroxiredoxin activity
C1N50_RS01700	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C1N50_RS01710	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C1N50_RS01755	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C1N50_RS01760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C1N50_RS01770	COG2965	DNA replication, synthesis of RNA primer
C1N50_RS01790	COG0305	Participates in initiation and elongation during chromosome replication
C1N50_RS01795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C1N50_RS01805	COG0432	Pfam Uncharacterised protein family UPF0047
C1N50_RS01820	COG0735	belongs to the Fur family
C1N50_RS01825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1N50_RS01845	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C1N50_RS01920	COG1410	methionine synthase
C1N50_RS01920	COG0646	methionine synthase
C1N50_RS01925	COG0527	aspartate kinase activity
C1N50_RS01935	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C1N50_RS01945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C1N50_RS01960	COG0629	single-stranded DNA binding
C1N50_RS01965	COG2200	EAL domain
C1N50_RS01965	COG2199	diguanylate cyclase activity
C1N50_RS01990	COG3409	Peptidoglycan-binding domain 1 protein
C1N50_RS01990	COG3267	Type II secretory pathway component ExeA
C1N50_RS02000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1N50_RS02005	COG1459	type II secretion system
C1N50_RS02015	COG2165	general secretion pathway protein
C1N50_RS02050	COG1077	Cell shape determining protein MreB Mrl
C1N50_RS02055	COG1792	Involved in formation and maintenance of cell shape
C1N50_RS02060	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C1N50_RS02065	COG0424	maF-like protein
C1N50_RS02075	COG3164	Protein of unknown function
C1N50_RS02080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1N50_RS02085	COG0312	modulator of DNA gyrase
C1N50_RS02090	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C1N50_RS02105	COG0564	pseudouridine synthase activity
C1N50_RS02110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C1N50_RS02120	COG0312	modulator of DNA gyrase
C1N50_RS02125	COG2239	Acts as a magnesium transporter
C1N50_RS02130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_RS02140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_RS02145	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C1N50_RS02155	COG1137	ATPase activity
C1N50_RS02160	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C1N50_RS02170	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C1N50_RS02170	COG0517	IMP dehydrogenase activity
C1N50_RS02180	COG1127	ABC transporter
C1N50_RS02185	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C1N50_RS02190	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C1N50_RS02195	COG2854	intermembrane phospholipid transfer
C1N50_RS02205	COG5007	Belongs to the BolA IbaG family
C1N50_RS02215	COG0204	Acyl-transferase
C1N50_RS02220	COG0251	oxidation-reduction process
C1N50_RS02260	COG0456	acetyltransferase
C1N50_RS02270	COG0525	valine-tRNA ligase activity
C1N50_RS02275	COG2927	DNA polymerase III (CHI subunit)
C1N50_RS02285	COG0795	lipopolysaccharide-transporting ATPase activity
C1N50_RS02290	COG0795	lipopolysaccharide-transporting ATPase activity
C1N50_RS02300	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_RS02340	COG0726	polysaccharide deacetylase
C1N50_RS02345	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C1N50_RS02355	COG1447	Phosphotransferase system cellobiose-specific component IIA
C1N50_RS02360	COG1486	melibiose metabolic process
C1N50_RS02370	COG1609	Transcriptional regulator
C1N50_RS02430	COG1012	belongs to the aldehyde dehydrogenase family
C1N50_RS02530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C1N50_RS02535	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C1N50_RS02550	COG0762	integral membrane protein
C1N50_RS02555	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C1N50_RS02560	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C1N50_RS02575	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C1N50_RS02580	COG1678	Uncharacterized ACR, COG1678
C1N50_RS02585	COG0189	ligase activity
C1N50_RS02590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C1N50_RS02595	COG2356	endonuclease I
C1N50_RS02615	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C1N50_RS02635	COG0191	fructose-bisphosphate aldolase activity
C1N50_RS02640	COG0668	transmembrane transport
C1N50_RS02655	COG0583	DNA-binding transcription factor activity
C1N50_RS02665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1N50_RS02675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C1N50_RS02685	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C1N50_RS02700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1N50_RS02705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1N50_RS02725	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C1N50_RS02735	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C1N50_RS02740	COG1595	DNA-templated transcription, initiation
C1N50_RS02755	COG3086	response to oxidative stress
C1N50_RS02775	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C1N50_RS02780	COG1381	Involved in DNA repair and RecF pathway recombination
C1N50_RS02785	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C1N50_RS02810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C1N50_RS02815	COG3956	TIGRFAM MazG family protein
C1N50_RS02825	COG0148	phosphopyruvate hydratase activity
C1N50_RS02835	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C1N50_RS02865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C1N50_RS02875	COG1546	Belongs to the CinA family
C1N50_RS02880	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C1N50_RS02895	COG0527	aspartate kinase activity
C1N50_RS02980	COG3630	sodium ion export across plasma membrane
C1N50_RS02985	COG5016	pyruvate
C1N50_RS02985	COG0511	ligase activity, forming carbon-carbon bonds
C1N50_RS02990	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
C1N50_RS03000	COG1238	metal cluster binding
C1N50_RS03005	COG0612	Peptidase, M16
C1N50_RS03025	COG4536	flavin adenine dinucleotide binding
C1N50_RS03030	COG4137	Cytochrome C assembly protein
C1N50_RS03035	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C1N50_RS03060	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C1N50_RS03065	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
C1N50_RS03070	COG0237	dephospho-CoA kinase activity
C1N50_RS03080	COG1459	type II secretion system
C1N50_RS03085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1N50_RS03110	COG2186	Transcriptional regulator
C1N50_RS03115	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C1N50_RS03120	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N50_RS03125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1N50_RS03145	COG0288	reversible hydration of carbon dioxide
C1N50_RS03150	COG0659	secondary active sulfate transmembrane transporter activity
C1N50_RS03155	COG1131	(ABC) transporter
C1N50_RS03160	COG0842	Transport permease protein
C1N50_RS03165	COG1560	Kdo2-lipid A biosynthetic process
C1N50_RS03180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C1N50_RS03195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C1N50_RS03210	COG1643	Atp-dependent helicase
C1N50_RS03215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1N50_RS03220	COG1752	Esterase of the alpha-beta hydrolase superfamily
C1N50_RS03225	COG1049	propionate catabolic process, 2-methylcitrate cycle
C1N50_RS03245	COG0004	ammonium transporteR
C1N50_RS03250	COG1840	ABC-type Fe3 transport system, periplasmic component
C1N50_RS03260	COG3842	ATPase activity
C1N50_RS03265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1N50_RS03280	COG2971	BadF BadG BcrA BcrD
C1N50_RS03290	COG4608	Belongs to the ABC transporter superfamily
C1N50_RS03295	COG0444	Belongs to the ABC transporter superfamily
C1N50_RS03300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N50_RS03310	COG0747	negative chemotaxis
C1N50_RS03315	COG0784	Response regulator, receiver
C1N50_RS03315	COG2198	Histidine kinase
C1N50_RS03315	COG2205	protein histidine kinase activity
C1N50_RS03315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N50_RS03330	COG0628	permease
C1N50_RS03355	COG0739	heme binding
C1N50_RS03360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C1N50_RS03370	COG2027	D-alanyl-D-alanine carboxypeptidase
C1N50_RS03375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C1N50_RS03380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1N50_RS03385	COG1534	Rna-binding protein
C1N50_RS03395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C1N50_RS03400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C1N50_RS03410	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C1N50_RS03430	COG0195	Participates in both transcription termination and antitermination
C1N50_RS03450	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C1N50_RS03470	COG0534	Mate efflux family protein
C1N50_RS03475	COG0826	peptidase U32
C1N50_RS03480	COG0826	peptidase U32
C1N50_RS03490	COG3154	lipid carrier protein
C1N50_RS03495	COG3153	acetyltransferase
C1N50_RS03520	COG0084	hydrolase, TatD family'
C1N50_RS03525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1N50_RS03535	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C1N50_RS03545	COG0813	purine-nucleoside phosphorylase activity
C1N50_RS03555	COG0560	Phosphoserine phosphatase
C1N50_RS03565	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C1N50_RS03570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C1N50_RS03600	COG1022	Amp-dependent synthetase and ligase
C1N50_RS03605	COG0741	lytic transglycosylase activity
C1N50_RS03610	COG0583	DNA-binding transcription factor activity
C1N50_RS03630	COG4964	Belongs to the GSP D family
C1N50_RS03690	COG0583	DNA-binding transcription factor activity
C1N50_RS03695	COG0531	amino acid
C1N50_RS03700	COG2731	YhcH YjgK YiaL family protein
C1N50_RS03705	COG3250	beta-galactosidase activity
C1N50_RS03710	COG1609	Transcriptional regulator
C1N50_RS03715	COG0768	penicillin binding
C1N50_RS03725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1N50_RS03730	COG1085	galactose-1-phosphate uridylyltransferase
C1N50_RS03740	COG2017	converts alpha-aldose to the beta-anomer
C1N50_RS03750	COG1609	Transcriptional regulator
C1N50_RS03765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1N50_RS03785	COG0741	lytic transglycosylase activity
C1N50_RS03800	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C1N50_RS03805	COG1349	DNA-binding transcription factor activity
C1N50_RS03815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C1N50_RS03825	COG2271	Major facilitator Superfamily
C1N50_RS03830	COG0584	glycerophosphoryl diester phosphodiesterase
C1N50_RS03835	COG2171	N-acyltransferase activity
C1N50_RS03850	COG3141	response to X-ray
C1N50_RS03870	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C1N50_RS03875	COG1074	ATP-dependent DNA helicase activity
C1N50_RS03880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C1N50_RS03890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C1N50_RS03890	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C1N50_RS03905	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C1N50_RS03910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C1N50_RS03915	COG2166	iron-sulfur cluster assembly
C1N50_RS03920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C1N50_RS03925	COG0693	protein deglycase activity
C1N50_RS03930	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C1N50_RS03955	COG1595	DNA-templated transcription, initiation
C1N50_RS03985	COG0271	Belongs to the BolA IbaG family
C1N50_RS04020	COG1477	protein flavinylation
C1N50_RS04035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C1N50_RS04040	COG0514	ATP-dependent DNA helicase (RecQ)
C1N50_RS04045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1N50_RS04060	COG0733	neurotransmitter:sodium symporter activity
C1N50_RS04085	COG1720	tRNA m6t6A37 methyltransferase activity
C1N50_RS04100	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C1N50_RS04130	COG3098	single-species biofilm formation
C1N50_RS04135	COG0564	pseudouridine synthase activity
C1N50_RS04150	COG0024	Methionine aminopeptidase
C1N50_RS04175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C1N50_RS04180	COG0575	Belongs to the CDS family
C1N50_RS04190	COG0750	zinc metalloprotease
C1N50_RS04200	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C1N50_RS04205	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C1N50_RS04230	COG0587	DNA-directed DNA polymerase activity
C1N50_RS04250	COG0347	Belongs to the P(II) protein family
C1N50_RS04265	COG0741	lytic transglycosylase activity
C1N50_RS04265	COG1388	LysM domain
C1N50_RS04275	COG2226	methyltransferase
C1N50_RS04285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C1N50_RS04310	COG1960	acyl-CoA dehydrogenase activity
C1N50_RS04315	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C1N50_RS04320	COG0121	glutamine amidotransferase
C1N50_RS04325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C1N50_RS04330	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C1N50_RS04335	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C1N50_RS04340	COG2233	PERMEase
C1N50_RS04360	COG4783	chaperone-mediated protein folding
C1N50_RS04375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C1N50_RS04380	COG2716	regulation of RNA biosynthetic process
C1N50_RS04385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C1N50_RS04390	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C1N50_RS04410	COG1393	Belongs to the ArsC family
C1N50_RS04435	COG2837	iron assimilation
C1N50_RS04440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_RS04450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_RS04455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_RS04460	COG1334	flagellar protein FlaG
C1N50_RS04465	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C1N50_RS04475	COG1516	flagellar protein fliS
C1N50_RS04495	COG1677	Flagellar hook-basal body complex protein FliE
C1N50_RS04505	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C1N50_RS04560	COG1987	bacterial-type flagellum assembly
C1N50_RS04565	COG1684	flagellar biosynthetic protein fliR
C1N50_RS04600	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C1N50_RS04605	COG0784	Response regulator, receiver
C1N50_RS04605	COG0643	Histidine kinase
C1N50_RS04605	COG2198	Histidine kinase
C1N50_RS04610	COG2201	protein-glutamate methylesterase activity
C1N50_RS04615	COG1192	Involved in chromosome partitioning
C1N50_RS04625	COG0835	chemotaxis
C1N50_RS04635	COG4133	protoheme IX ABC transporter activity
C1N50_RS04640	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1N50_RS04645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1N50_RS04660	COG1138	Cytochrome C-type biogenesis protein
C1N50_RS04665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1N50_RS04675	COG4235	cytochrome complex assembly
C1N50_RS04675	COG3088	subunit of a heme lyase
C1N50_RS04680	COG2853	Lipoprotein
C1N50_RS04685	COG2067	long-chain fatty acid transport protein
C1N50_RS04710	COG0183	Belongs to the thiolase family
C1N50_RS04725	COG2062	phosphohistidine phosphatase, SixA
C1N50_RS04735	COG2890	protein-(glutamine-N5) methyltransferase activity
C1N50_RS04745	COG2860	membrane
C1N50_RS04750	COG3101	peptidyl-lysine hydroxylation
C1N50_RS04775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1N50_RS04785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1N50_RS04790	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C1N50_RS04815	COG0285	dihydrofolate synthase activity
C1N50_RS04820	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C1N50_RS04825	COG1286	toxin biosynthetic process
C1N50_RS04830	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C1N50_RS04835	COG0583	DNA-binding transcription factor activity
C1N50_RS04840	COG0745	RESPONSE REGULATOR receiver
C1N50_RS04850	COG2832	Protein of unknown function (DUF454)
C1N50_RS04860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C1N50_RS04870	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C1N50_RS04875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C1N50_RS04880	COG0814	amino acid
C1N50_RS04885	COG0251	oxidation-reduction process
C1N50_RS04895	COG2964	Protein conserved in bacteria
C1N50_RS04905	COG2983	Belongs to the UPF0260 family
C1N50_RS04910	COG2261	transglycosylase associated protein
C1N50_RS04915	COG2985	domain, Protein
C1N50_RS04920	COG0076	glutamate decarboxylase activity
C1N50_RS04925	COG0668	transmembrane transport
C1N50_RS04935	COG0346	lactoylglutathione lyase activity
C1N50_RS04945	COG1785	Belongs to the alkaline phosphatase family
C1N50_RS04965	COG2226	methyltransferase
C1N50_RS04985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C1N50_RS04990	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N50_RS05000	COG3139	Protein of unknown function (DUF1315)
C1N50_RS05005	COG0252	asparaginase activity
C1N50_RS05010	COG0616	signal peptide processing
C1N50_RS05015	COG1902	pentaerythritol trinitrate reductase activity
C1N50_RS05015	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1N50_RS05020	COG0778	Nitroreductase
C1N50_RS05025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1N50_RS05040	COG0123	including yeast histone deacetylase and acetoin utilization protein
C1N50_RS05050	COG4269	membrane
C1N50_RS05065	COG3083	sulfuric ester hydrolase activity
C1N50_RS05090	COG1757	Na H antiporter
C1N50_RS05095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C1N50_RS05105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1N50_RS05110	COG2095	MarC family integral membrane protein
C1N50_RS05115	COG1012	belongs to the aldehyde dehydrogenase family
C1N50_RS05115	COG1454	alcohol dehydrogenase
C1N50_RS05120	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_RS05135	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C1N50_RS05150	COG2056	Na+-H+ antiporter family
C1N50_RS05160	COG2885	chlorophyll binding
C1N50_RS05170	COG0346	lactoylglutathione lyase activity
C1N50_RS05175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C1N50_RS05180	COG4660	Part of a membrane complex involved in electron transport
C1N50_RS05185	COG4659	FMN binding
C1N50_RS05190	COG4658	electron transport chain
C1N50_RS05195	COG4656	Part of a membrane complex involved in electron transport
C1N50_RS05205	COG4657	Part of a membrane complex involved in electron transport
C1N50_RS05210	COG1882	Formate acetyltransferase
C1N50_RS05220	COG0745	RESPONSE REGULATOR receiver
C1N50_RS05260	COG0556	nucleotide-excision repair
C1N50_RS05275	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C1N50_RS05280	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C1N50_RS05285	COG0521	Mo-molybdopterin cofactor biosynthetic process
C1N50_RS05295	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C1N50_RS05300	COG0314	molybdopterin synthase activity
C1N50_RS05310	COG0601	transmembrane transport
C1N50_RS05315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N50_RS05320	COG0444	Belongs to the ABC transporter superfamily
C1N50_RS05330	COG0435	Glutathione S-transferase
C1N50_RS05335	COG0857	belongs to the CobB CobQ family
C1N50_RS05335	COG0280	phosphate acetyltransferase
C1N50_RS05360	COG4120	Belongs to the binding-protein-dependent transport system permease family
C1N50_RS05365	COG1122	ATPase activity
C1N50_RS05370	COG0366	Alpha amylase catalytic
C1N50_RS05380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1N50_RS05385	COG0653	protein targeting
C1N50_RS05390	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C1N50_RS05400	COG2186	Transcriptional regulator
C1N50_RS05430	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C1N50_RS05435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N50_RS05440	COG0659	secondary active sulfate transmembrane transporter activity
C1N50_RS05450	COG1530	ribonuclease E activity
C1N50_RS05455	COG0564	pseudouridine synthase activity
C1N50_RS05460	COG0424	maF-like protein
C1N50_RS05465	COG1399	metal-binding, possibly nucleic acid-binding protein
C1N50_RS05480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1N50_RS05510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C1N50_RS05525	COG0084	hydrolase, TatD family'
C1N50_RS05530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N50_RS05530	COG1263	PTS System
C1N50_RS05545	COG0733	neurotransmitter:sodium symporter activity
C1N50_RS05560	COG4667	esterase of the alpha-beta hydrolase superfamily
C1N50_RS05590	COG2272	Belongs to the type-B carboxylesterase lipase family
C1N50_RS05600	COG3710	Transcriptional regulator
C1N50_RS05615	COG1940	carbohydrate kinase activity
C1N50_RS05620	COG0784	Response regulator, receiver
C1N50_RS05620	COG0835	chemotaxis
C1N50_RS05640	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_RS05645	COG0616	signal peptide processing
C1N50_RS05655	COG0539	negative regulation of cytoplasmic translation
C1N50_RS05665	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C1N50_RS05670	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C1N50_RS05680	COG4166	transmembrane transport
C1N50_RS05695	COG3009	Protein conserved in bacteria
C1N50_RS05700	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C1N50_RS05700	COG3008	intermembrane lipid transfer
C1N50_RS05705	COG2995	paraquat-inducible protein a
C1N50_RS05710	COG1609	Transcriptional regulator
C1N50_RS05715	COG3250	beta-galactosidase activity
C1N50_RS05725	COG4580	involved in the transport of maltose and maltodextrins
C1N50_RS05735	COG2211	Major facilitator Superfamily
C1N50_RS05740	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C1N50_RS05755	COG4232	protein-disulfide reductase activity
C1N50_RS05760	COG3118	belongs to the thioredoxin family
C1N50_RS05770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C1N50_RS05780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N50_RS05795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N50_RS05805	COG0577	efflux transmembrane transporter activity
C1N50_RS05810	COG0577	efflux transmembrane transporter activity
C1N50_RS05810	COG1136	(ABC) transporter
C1N50_RS05815	COG0577	efflux transmembrane transporter activity
C1N50_RS05815	COG1136	(ABC) transporter
C1N50_RS05830	COG2176	DNA-directed DNA polymerase activity
C1N50_RS05900	COG5002	protein histidine kinase activity
C1N50_RS05900	COG3850	Histidine kinase
C1N50_RS05905	COG0745	RESPONSE REGULATOR receiver
C1N50_RS05910	COG0463	Glycosyl transferase, family 2
C1N50_RS05915	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C1N50_RS05925	COG0840	transmembrane signaling receptor activity
C1N50_RS05940	COG2175	clavaminate synthase activity
C1N50_RS05945	COG2964	Protein conserved in bacteria
C1N50_RS05960	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1N50_RS05985	COG1032	radical SAM domain protein
C1N50_RS05990	COG1716	ATPase activity
C1N50_RS05990	COG5001	Diguanylate cyclase
C1N50_RS06020	COG2350	Protein conserved in bacteria
C1N50_RS06050	COG1301	dicarboxylic acid transport
C1N50_RS06055	COG0159	tryptophan synthase activity
C1N50_RS06065	COG0135	phosphoribosylanthranilate isomerase activity
C1N50_RS06065	COG0134	indole-3-glycerol-phosphate synthase activity
C1N50_RS06075	COG0512	Glutamine amidotransferase of anthranilate synthase
C1N50_RS06080	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1N50_RS06090	COG0613	PHP domain protein
C1N50_RS06095	COG0009	L-threonylcarbamoyladenylate synthase
C1N50_RS06105	COG1187	pseudouridine synthase activity
C1N50_RS06125	COG0417	DNA replication proofreading
C1N50_RS06130	COG2197	response regulator
C1N50_RS06135	COG0322	excinuclease ABC activity
C1N50_RS06175	COG0019	diaminopimelate decarboxylase activity
C1N50_RS06190	COG1058	Belongs to the CinA family
C1N50_RS06190	COG1546	Belongs to the CinA family
C1N50_RS06200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1N50_RS06205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1N50_RS06230	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C1N50_RS06240	COG0437	4 iron, 4 sulfur cluster binding
C1N50_RS06245	COG3301	Polysulphide reductase, NrfD
C1N50_RS06250	COG1138	Cytochrome C-type biogenesis protein
C1N50_RS06260	COG3088	subunit of a heme lyase
C1N50_RS06260	COG4235	cytochrome complex assembly
C1N50_RS06295	COG2989	Protein conserved in bacteria
C1N50_RS06300	COG3108	Peptidase M15
C1N50_RS06305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1N50_RS06320	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C1N50_RS06345	COG1846	Transcriptional regulator
C1N50_RS06350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1N50_RS06355	COG0840	transmembrane signaling receptor activity
C1N50_RS06375	COG1448	Aminotransferase
C1N50_RS06395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N50_RS06410	COG0017	Asparaginyl-tRNA synthetase
C1N50_RS06420	COG0720	synthase
C1N50_RS06425	COG2197	response regulator
C1N50_RS06440	COG1760	l-serine dehydratase
C1N50_RS06445	COG0814	amino acid
C1N50_RS06460	COG0784	Response regulator, receiver
C1N50_RS06460	COG2205	protein histidine kinase activity
C1N50_RS06465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1N50_RS06480	COG3106	COG3106 Predicted ATPase
C1N50_RS06495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N50_RS06790	COG2801	Transposase and inactivated derivatives
C1N50_RS06920	COG2801	Transposase and inactivated derivatives
C1N50_RS07195	COG2801	Transposase and inactivated derivatives
C1N50_RS07240	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C1N50_RS07260	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C1N50_RS07290	COG2801	Transposase and inactivated derivatives
C1N50_RS07330	COG4221	oxidoreductase activity
C1N50_RS07345	COG3340	Belongs to the peptidase S51 family
C1N50_RS07375	COG0456	acetyltransferase
C1N50_RS07380	COG0471	metal ion transport
C1N50_RS07385	COG4191	Histidine kinase
C1N50_RS07385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N50_RS07405	COG1280	lysine exporter protein (LysE YggA)
C1N50_RS07410	COG1328	CTP reductase activity
C1N50_RS07415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1N50_RS07425	COG0861	Integral membrane protein TerC family
C1N50_RS07435	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C1N50_RS07440	COG4221	oxidoreductase activity
C1N50_RS07445	COG1454	alcohol dehydrogenase
C1N50_RS07450	COG0814	amino acid
C1N50_RS07470	COG1132	(ABC) transporter
C1N50_RS07475	COG1132	(ABC) transporter
C1N50_RS07480	COG2165	general secretion pathway protein
C1N50_RS07485	COG0583	DNA-binding transcription factor activity
C1N50_RS07510	COG0443	Heat shock 70 kDa protein
C1N50_RS07515	COG0443	Heat shock 70 kDa protein
C1N50_RS07525	COG3706	GGDEF domain
C1N50_RS07555	COG3227	Zinc metalloprotease (Elastase)
C1N50_RS07575	COG3842	ATPase activity
C1N50_RS07580	COG3459	Glycosyltransferase 36 associated
C1N50_RS07590	COG1653	transport
C1N50_RS07600	COG0395	ABC-type sugar transport system, permease component
C1N50_RS07615	COG0243	molybdopterin cofactor binding
C1N50_RS07620	COG0437	4 iron, 4 sulfur cluster binding
C1N50_RS07625	COG3302	dmso reductase anchor subunit
C1N50_RS07640	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C1N50_RS07645	COG1643	Atp-dependent helicase
C1N50_RS07670	COG3063	Type IV pilus biogenesis stability protein PilW
C1N50_RS07700	COG0531	amino acid
C1N50_RS07705	COG1280	lysine exporter protein (LysE YggA)
C1N50_RS07710	COG1560	Kdo2-lipid A biosynthetic process
C1N50_RS07730	COG1846	Transcriptional regulator
C1N50_RS07740	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C1N50_RS07745	COG1280	lysine exporter protein (LysE YggA)
C1N50_RS07780	COG1115	amino acid carrier protein
C1N50_RS07805	COG1368	sulfuric ester hydrolase activity
C1N50_RS07820	COG0215	cysteine-tRNA ligase activity
C1N50_RS07825	COG0534	Mate efflux family protein
C1N50_RS07830	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C1N50_RS07840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1N50_RS07845	COG0456	acetyltransferase
C1N50_RS07850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C1N50_RS07855	COG0662	Cupin 2, conserved barrel domain protein
C1N50_RS07860	COG0527	aspartate kinase activity
C1N50_RS07870	COG1858	cytochrome C peroxidase
C1N50_RS07875	COG1404	Belongs to the peptidase S8 family
C1N50_RS07880	COG3227	Zinc metalloprotease (Elastase)
C1N50_RS07920	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C1N50_RS07950	COG0210	DNA helicase
C1N50_RS07975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N50_RS07990	COG3290	protein histidine kinase activity
C1N50_RS07995	COG4565	transcriptional regulatory protein
C1N50_RS08000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C1N50_RS08005	COG0363	glucosamine-6-phosphate deaminase activity
C1N50_RS08010	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C1N50_RS08040	COG3284	Transcriptional regulator
C1N50_RS08045	COG1012	belongs to the aldehyde dehydrogenase family
C1N50_RS08050	COG2358	TRAP transporter, solute receptor (TAXI family
C1N50_RS08055	COG0840	transmembrane signaling receptor activity
C1N50_RS08060	COG0730	response to heat
C1N50_RS08090	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C1N50_RS08200	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C1N50_RS08205	COG0372	Belongs to the citrate synthase family
C1N50_RS08215	COG2828	Protein conserved in bacteria
C1N50_RS08250	COG0561	phosphatase activity
C1N50_RS08255	COG0602	queuosine metabolic process
C1N50_RS08265	COG3706	GGDEF domain
C1N50_RS08315	COG0840	transmembrane signaling receptor activity
C1N50_RS08320	COG1254	Belongs to the acylphosphatase family
C1N50_RS08325	COG2920	part of a sulfur-relay system
C1N50_RS08335	COG0670	Belongs to the BI1 family
C1N50_RS08340	COG1126	abc transporter atp-binding protein
C1N50_RS08345	COG0765	amino acid transport
C1N50_RS08350	COG4597	amino acid ABC transporter
C1N50_RS08355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N50_RS08375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1N50_RS08400	COG3008	intermembrane lipid transfer
C1N50_RS08405	COG2995	paraquat-inducible protein a
C1N50_RS08410	COG1132	(ABC) transporter
C1N50_RS08415	COG1956	GAF domain-containing protein
C1N50_RS08420	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C1N50_RS08435	COG0308	aminopeptidase N
C1N50_RS08445	COG2902	Dehydrogenase
C1N50_RS08470	COG0488	(ABC) transporter
C1N50_RS08490	COG1067	ATP-dependent peptidase activity
C1N50_RS08615	COG3278	Belongs to the heme-copper respiratory oxidase family
C1N50_RS08630	COG2010	Cytochrome c
C1N50_RS08640	COG2217	Heavy metal translocating P-type atpase
C1N50_RS08655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1N50_RS08660	COG0589	response to stress
C1N50_RS08685	COG3842	ATPase activity
C1N50_RS08695	COG1177	transmembrane transport
C1N50_RS08705	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C1N50_RS08710	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C1N50_RS08725	COG0437	4 iron, 4 sulfur cluster binding
C1N50_RS08730	COG3383	formate dehydrogenase (NAD+) activity
C1N50_RS08730	COG0243	molybdopterin cofactor binding
C1N50_RS08740	COG3381	protein complex oligomerization
C1N50_RS08760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C1N50_RS08765	COG0488	(ABC) transporter
C1N50_RS08785	COG4191	Histidine kinase
C1N50_RS08790	COG2204	response regulator
C1N50_RS08800	COG4662	Binding-protein-dependent transport system inner membrane component
C1N50_RS08805	COG3842	ATPase activity
C1N50_RS08815	COG0303	'Molybdopterin
C1N50_RS08825	COG1940	carbohydrate kinase activity
C1N50_RS08830	COG3148	PFAM DTW domain containing protein
C1N50_RS08880	COG3290	protein histidine kinase activity
C1N50_RS08880	COG0840	transmembrane signaling receptor activity
C1N50_RS08885	COG0791	NLP P60 protein
C1N50_RS08895	COG3706	GGDEF domain
C1N50_RS08900	COG2201	protein-glutamate methylesterase activity
C1N50_RS08905	COG3001	Fructosamine kinase
C1N50_RS08915	COG0307	riboflavin synthase, alpha
C1N50_RS08920	COG0534	Mate efflux family protein
C1N50_RS08930	COG1793	dna ligase
C1N50_RS08940	COG2885	chlorophyll binding
C1N50_RS08960	COG2204	response regulator
C1N50_RS08965	COG0438	transferase activity, transferring glycosyl groups
C1N50_RS08970	COG0438	transferase activity, transferring glycosyl groups
C1N50_RS09000	COG0438	transferase activity, transferring glycosyl groups
C1N50_RS09005	COG1215	transferase activity, transferring glycosyl groups
C1N50_RS09010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C1N50_RS09020	COG3064	Membrane
C1N50_RS09030	COG0116	Belongs to the methyltransferase superfamily
C1N50_RS09030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C1N50_RS09045	COG3300	MHYT domain
C1N50_RS09045	COG5001	Diguanylate cyclase
C1N50_RS09050	COG3437	response regulator, receiver
C1N50_RS09050	COG2205	protein histidine kinase activity
C1N50_RS09050	COG4999	Histidine kinase
C1N50_RS09050	COG3850	Histidine kinase
C1N50_RS09070	COG0110	maltose O-acetyltransferase activity
C1N50_RS09075	COG2205	protein histidine kinase activity
C1N50_RS09075	COG0784	Response regulator, receiver
C1N50_RS09095	COG1846	Transcriptional regulator
C1N50_RS09110	COG3247	response to pH
C1N50_RS09115	COG0668	transmembrane transport
C1N50_RS09125	COG1404	Belongs to the peptidase S8 family
C1N50_RS09135	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C1N50_RS09185	COG0625	glutathione transferase activity
C1N50_RS09195	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
C1N50_RS09210	COG2195	Cleaves the N-terminal amino acid of tripeptides
C1N50_RS09245	COG0813	purine-nucleoside phosphorylase activity
C1N50_RS09270	COG1451	nucleotide metabolic process
C1N50_RS09275	COG2165	general secretion pathway protein
C1N50_RS09300	COG0583	DNA-binding transcription factor activity
C1N50_RS09330	COG4139	cobalamin transport
C1N50_RS09345	COG2062	phosphohistidine phosphatase, SixA
C1N50_RS09355	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C1N50_RS09365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C1N50_RS09375	COG0702	epimerase
C1N50_RS09380	COG1823	symporter activity
C1N50_RS09390	COG2925	Exonuclease
C1N50_RS09400	COG1346	cytolysis
C1N50_RS09450	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N50_RS09455	COG4605	iron ion homeostasis
C1N50_RS09460	COG4607	ABC-type enterochelin transport system periplasmic component
C1N50_RS09465	COG4774	siderophore transport
C1N50_RS09485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1N50_RS09500	COG1132	(ABC) transporter
C1N50_RS09505	COG3433	isochorismatase activity
C1N50_RS09505	COG1535	isochorismatase
C1N50_RS09510	COG0072	phenylalanine-tRNA ligase activity
C1N50_RS09510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1N50_RS09520	COG3706	GGDEF domain
C1N50_RS09560	COG0251	oxidation-reduction process
C1N50_RS09605	COG2188	Transcriptional regulator
C1N50_RS09615	COG0010	Belongs to the arginase family
C1N50_RS09625	COG2986	histidine ammonia-lyase
C1N50_RS09670	COG0247	lactate metabolic process
C1N50_RS09670	COG0277	FAD linked oxidase domain protein
C1N50_RS09815	COG1643	Atp-dependent helicase
C1N50_RS09825	COG2949	membrane
C1N50_RS09830	COG0471	metal ion transport
C1N50_RS09835	COG3706	GGDEF domain
C1N50_RS09855	COG0492	ferredoxin-NADP+ reductase activity
C1N50_RS09860	COG4988	ABC transporter
C1N50_RS09865	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C1N50_RS09875	COG0583	DNA-binding transcription factor activity
C1N50_RS09880	COG2200	EAL domain
C1N50_RS09900	COG5001	Diguanylate cyclase
C1N50_RS09915	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C1N50_RS09925	COG4191	Histidine kinase
C1N50_RS09925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N50_RS09940	COG3070	regulator of competence-specific genes
C1N50_RS09955	COG2431	L-lysine efflux transmembrane transporter activity
C1N50_RS09965	COG0076	glutamate decarboxylase activity
C1N50_RS09970	COG1737	Transcriptional regulator
C1N50_RS09980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C1N50_RS09990	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C1N50_RS10025	COG0534	Mate efflux family protein
C1N50_RS10030	COG0702	epimerase
C1N50_RS10035	COG4667	esterase of the alpha-beta hydrolase superfamily
C1N50_RS10045	COG2814	Major facilitator Superfamily
C1N50_RS10050	COG1187	pseudouridine synthase activity
C1N50_RS10055	COG1061	Type III restriction enzyme res subunit
C1N50_RS10120	COG3313	Fe-S protein
C1N50_RS10130	COG0659	secondary active sulfate transmembrane transporter activity
C1N50_RS10155	COG0493	'glutamate synthase
C1N50_RS10165	COG0398	Pfam SNARE associated Golgi protein
C1N50_RS10170	COG4134	Bacterial extracellular solute-binding protein
C1N50_RS10175	COG4135	transport system, permease component
C1N50_RS10180	COG4136	ATPase activity
C1N50_RS10185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C1N50_RS10195	COG2814	Major facilitator Superfamily
C1N50_RS10200	COG3604	Transcriptional regulator
C1N50_RS10205	COG1151	hydroxylamine reductase activity
C1N50_RS10210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1N50_RS10220	COG0564	pseudouridine synthase activity
C1N50_RS10225	COG0733	neurotransmitter:sodium symporter activity
C1N50_RS10235	COG0626	cystathionine gamma-synthase activity
C1N50_RS10240	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C1N50_RS10260	COG2818	Glycosylase
C1N50_RS10280	COG1983	PspC domain protein
C1N50_RS10290	COG1842	Phage shock protein A
C1N50_RS10295	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C1N50_RS10305	COG4168	peptide transport system, permease
C1N50_RS10310	COG4171	peptide transport system, permease
C1N50_RS10320	COG4172	Belongs to the ABC transporter superfamily
C1N50_RS10330	COG1227	inorganic diphosphatase activity
C1N50_RS10345	COG0243	molybdopterin cofactor binding
C1N50_RS10350	COG3005	denitrification pathway
C1N50_RS10355	COG4459	periplasmic nitrate reductase
C1N50_RS10360	COG0390	transport system, permease component
C1N50_RS10365	COG2116	formate transmembrane transporter activity
C1N50_RS10390	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C1N50_RS10395	COG1435	thymidine kinase activity
C1N50_RS10400	COG0215	cysteine-tRNA ligase activity
C1N50_RS10405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C1N50_RS10410	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C1N50_RS10415	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C1N50_RS10420	COG3012	SEC-C Motif Domain Protein
C1N50_RS10425	COG0140	phosphoribosyl-ATP diphosphatase activity
C1N50_RS10425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C1N50_RS10435	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C1N50_RS10440	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C1N50_RS10445	COG0131	Imidazoleglycerol-phosphate dehydratase
C1N50_RS10445	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C1N50_RS10455	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C1N50_RS10465	COG1757	Na H antiporter
C1N50_RS10475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N50_RS10495	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C1N50_RS10515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C1N50_RS10530	COG0300	oxidoreductase activity
C1N50_RS10555	COG2226	methyltransferase
C1N50_RS10575	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C1N50_RS10585	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C1N50_RS10595	COG1674	ftsk spoiiie
C1N50_RS10605	COG0686	Belongs to the AlaDH PNT family
C1N50_RS10615	COG0583	DNA-binding transcription factor activity
C1N50_RS10640	COG0402	S-adenosylhomocysteine deaminase activity
C1N50_RS10645	COG4934	collagen metabolic process
C1N50_RS10650	COG0270	DNA (cytosine-5-)-methyltransferase activity
C1N50_RS10660	COG3568	Endonuclease Exonuclease Phosphatase
C1N50_RS10680	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C1N50_RS10695	COG1288	antiporter activity
C1N50_RS10705	COG2186	Transcriptional regulator
C1N50_RS10715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N50_RS10720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N50_RS10745	COG0747	negative chemotaxis
C1N50_RS10750	COG4608	Belongs to the ABC transporter superfamily
C1N50_RS10755	COG0444	Belongs to the ABC transporter superfamily
C1N50_RS10760	COG0534	Mate efflux family protein
C1N50_RS10765	COG2824	Alkylphosphonate utilization operon protein PhnA
C1N50_RS10785	COG3119	arylsulfatase activity
C1N50_RS10815	COG0457	Tetratricopeptide repeat
C1N50_RS10885	COG4790	Type iii secretion
C1N50_RS10890	COG4794	Type iii secretion
C1N50_RS10895	COG4791	protein targeting
C1N50_RS10900	COG4792	protein secretion
C1N50_RS10915	COG3177	Filamentation induced by cAMP protein fic
C1N50_RS10945	COG4669	(LipO)protein
C1N50_RS11075	COG0784	Response regulator, receiver
C1N50_RS11075	COG2205	protein histidine kinase activity
C1N50_RS11085	COG0754	glutathionylspermidine amidase activity
C1N50_RS11095	COG3766	membrane
C1N50_RS11110	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C1N50_RS11115	COG2885	chlorophyll binding
C1N50_RS11120	COG0823	Involved in the tonB-independent uptake of proteins
C1N50_RS11135	COG0811	peptide transport
C1N50_RS11140	COG0824	Thioesterase
C1N50_RS11150	COG4890	Cyd operon protein YbgT
C1N50_RS11155	COG1294	oxidase, subunit
C1N50_RS11160	COG1271	oxidase subunit
C1N50_RS11170	COG0632	four-way junction helicase activity
C1N50_RS11175	COG0840	transmembrane signaling receptor activity
C1N50_RS11190	COG1801	Protein of unknown function DUF72
C1N50_RS11210	COG4067	protein conserved in archaea
C1N50_RS11210	COG0189	ligase activity
C1N50_RS11230	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C1N50_RS11235	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C1N50_RS11245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1N50_RS11250	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C1N50_RS11255	COG0745	RESPONSE REGULATOR receiver
C1N50_RS11270	COG3070	regulator of competence-specific genes
C1N50_RS11290	COG0297	glycogen (starch) synthase activity
C1N50_RS11295	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1N50_RS11300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1N50_RS11330	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C1N50_RS11335	COG0542	response to heat
C1N50_RS11345	COG1278	Cold shock
C1N50_RS11355	COG1187	pseudouridine synthase activity
C1N50_RS11360	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C1N50_RS11365	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C1N50_RS11370	COG1199	ATP-dependent helicase activity
C1N50_RS11375	COG0730	response to heat
C1N50_RS11380	COG3923	Primosomal replication protein n
C1N50_RS11390	COG0708	Exodeoxyribonuclease III
C1N50_RS11425	COG1882	Formate acetyltransferase
C1N50_RS11435	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1N50_RS11455	COG2766	serine protein kinase
C1N50_RS11460	COG2718	Belongs to the UPF0229 family
C1N50_RS11465	COG2719	SpoVR family
C1N50_RS11485	COG1132	(ABC) transporter
C1N50_RS11490	COG0658	competence protein
C1N50_RS11490	COG2333	competence protein COMEC
C1N50_RS11500	COG4591	ABC-type transport system involved in lipoprotein release permease component
C1N50_RS11505	COG1136	(ABC) transporter
C1N50_RS11510	COG4591	ABC-type transport system involved in lipoprotein release permease component
C1N50_RS11520	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C1N50_RS11535	COG1252	NADH dehydrogenase
C1N50_RS11565	COG0537	adenosine 5'-monophosphoramidase activity
C1N50_RS11585	COG2217	Heavy metal translocating P-type atpase
C1N50_RS11595	COG0516	GMP reductase activity
C1N50_RS11595	COG0517	IMP dehydrogenase activity
C1N50_RS11600	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
C1N50_RS11605	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C1N50_RS11610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1N50_RS11620	COG3706	GGDEF domain
C1N50_RS11635	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C1N50_RS11640	COG1946	Acyl-CoA thioesterase
C1N50_RS11645	COG1522	sequence-specific DNA binding
C1N50_RS11665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N50_RS11720	COG2855	membrane
C1N50_RS11730	COG0583	DNA-binding transcription factor activity
C1N50_RS11735	COG2190	(PTS) system
C1N50_RS11735	COG1263	PTS System
C1N50_RS11735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N50_RS11750	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C1N50_RS11755	COG0596	Alpha beta hydrolase
C1N50_RS11765	COG1169	isochorismate synthase
C1N50_RS11770	COG0436	Aminotransferase
C1N50_RS11775	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C1N50_RS11795	COG1555	photosystem II stabilization
C1N50_RS11800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1N50_RS11805	COG0776	regulation of translation
C1N50_RS11810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C1N50_RS11845	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1N50_RS11850	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1N50_RS11855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1N50_RS11875	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N50_RS11880	COG0569	domain protein
C1N50_RS11885	COG0513	Belongs to the DEAD box helicase family
C1N50_RS11890	COG1253	flavin adenine dinucleotide binding
C1N50_RS11895	COG4771	TonB-dependent receptor
C1N50_RS11900	COG2977	Belongs to the P-Pant transferase superfamily
C1N50_RS11910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1N50_RS11910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1N50_RS11915	COG3433	isochorismatase activity
C1N50_RS11915	COG1535	isochorismatase
C1N50_RS11920	COG1021	2,3-dihydroxybenzoate-AMP ligase
C1N50_RS11925	COG1169	isochorismate synthase
C1N50_RS11935	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_RS11950	COG2226	methyltransferase
C1N50_RS11965	COG2852	Protein conserved in bacteria
C1N50_RS11970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1N50_RS11980	COG2951	lytic endotransglycosylase activity
C1N50_RS11995	COG2894	cell division
C1N50_RS12000	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C1N50_RS12005	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C1N50_RS12010	COG0318	PFAM AMP-dependent synthetase and ligase
C1N50_RS12015	COG2267	carboxylic ester hydrolase activity
C1N50_RS12020	COG3065	identical protein binding
C1N50_RS12030	COG1214	PFAM Peptidase M22, glycoprotease
C1N50_RS12035	COG1199	ATP-dependent helicase activity
C1N50_RS12045	COG0788	formyltetrahydrofolate deformylase activity
C1N50_RS12060	COG3102	Protein conserved in bacteria
C1N50_RS12095	COG1918	ferrous iron import across plasma membrane
C1N50_RS12100	COG4977	sequence-specific DNA binding
C1N50_RS12105	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C1N50_RS12110	COG1121	(ABC) transporter
C1N50_RS12115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1N50_RS12130	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N50_RS12135	COG0567	Dehydrogenase, E1 component
C1N50_RS12145	COG1053	succinate dehydrogenase
C1N50_RS12150	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C1N50_RS12165	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C1N50_RS12180	COG0033	Phosphoglucomutase
C1N50_RS12185	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C1N50_RS12190	COG0596	Alpha beta hydrolase
C1N50_RS12210	COG0735	belongs to the Fur family
C1N50_RS12215	COG2165	general secretion pathway protein
C1N50_RS12225	COG2190	(PTS) system
C1N50_RS12225	COG1263	PTS System
C1N50_RS12225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N50_RS12235	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C1N50_RS12240	COG1846	Transcriptional regulator
C1N50_RS12240	COG1940	carbohydrate kinase activity
C1N50_RS12245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C1N50_RS12245	COG4651	solute:proton antiporter activity
C1N50_RS12250	COG0367	asparagine synthase
C1N50_RS12260	COG3104	oligopeptide transport
C1N50_RS12265	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C1N50_RS12280	COG3710	Transcriptional regulator
C1N50_RS12300	COG0622	Phosphoesterase
C1N50_RS12330	COG1090	epimerase
C1N50_RS12335	COG0300	oxidoreductase activity
C1N50_RS12345	COG3118	belongs to the thioredoxin family
C1N50_RS12350	COG0457	Tetratricopeptide repeat
C1N50_RS12350	COG3118	belongs to the thioredoxin family
C1N50_RS12355	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C1N50_RS12360	COG1215	transferase activity, transferring glycosyl groups
C1N50_RS12365	COG1215	transferase activity, transferring glycosyl groups
C1N50_RS12370	COG1192	Involved in chromosome partitioning
C1N50_RS12385	COG2194	sulfuric ester hydrolase activity
C1N50_RS12390	COG0330	HflC and HflK could
C1N50_RS12395	COG1585	Membrane protein implicated in regulation of membrane protease activity
C1N50_RS12425	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
C1N50_RS12430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C1N50_RS12440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_RS12445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1N50_RS12450	COG2190	(PTS) system
C1N50_RS12455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_RS12460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_RS12465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_RS12480	COG1705	Flagellar rod assembly protein muramidase FlgJ
C1N50_RS12480	COG3951	Flagellar rod assembly protein muramidase FlgJ
C1N50_RS12485	COG1706	bacterial-type flagellum-dependent cell motility
C1N50_RS12490	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C1N50_RS12500	COG4787	bacterial-type flagellum-dependent cell motility
C1N50_RS12505	COG1749	Flagellar hook protein flgE
C1N50_RS12515	COG1558	bacterial-type flagellum-dependent cell motility
C1N50_RS12520	COG1815	bacterial-type flagellum-dependent cell motility
C1N50_RS12525	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C1N50_RS12530	COG0784	Response regulator, receiver
C1N50_RS12530	COG0835	chemotaxis
C1N50_RS12590	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C1N50_RS12605	COG2217	Heavy metal translocating P-type atpase
C1N50_RS12605	COG2608	mercury ion transmembrane transporter activity
C1N50_RS12650	COG2840	Smr protein MutS2
C1N50_RS12655	COG1187	pseudouridine synthase activity
C1N50_RS12660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C1N50_RS12665	COG0737	Belongs to the 5'-nucleotidase family
C1N50_RS12675	COG2912	Transglutaminase-like superfamily
C1N50_RS12680	COG3094	Invasion gene expression up-regulator, SirB
C1N50_RS12685	COG2890	protein-(glutamine-N5) methyltransferase activity
C1N50_RS12710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C1N50_RS12720	COG0012	GTP binding
C1N50_RS12835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1N50_RS12850	COG1702	phosphate starvation-inducible protein PhoH
C1N50_RS12860	COG4535	Mg2 and Co2 transporter CorC
C1N50_RS12865	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C1N50_RS12870	COG2888	peptidyl-tyrosine sulfation
C1N50_RS12880	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
C1N50_RS12885	COG1466	dna polymerase III delta subunit
C1N50_RS12890	COG0799	negative regulation of ribosome biogenesis
C1N50_RS12900	COG0768	penicillin binding
C1N50_RS12905	COG0772	Belongs to the SEDS family
C1N50_RS12910	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C1N50_RS12915	COG1686	Belongs to the peptidase S11 family
C1N50_RS12935	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C1N50_RS12940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C1N50_RS12945	COG0366	Alpha amylase catalytic
C1N50_RS12950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N50_RS12950	COG1263	PTS System
C1N50_RS12960	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C1N50_RS12965	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C1N50_RS12970	COG2011	ABC-type metal ion transport system permease component
C1N50_RS12975	COG1464	Belongs to the NlpA lipoprotein family
C1N50_RS12985	COG0737	Belongs to the 5'-nucleotidase family
C1N50_RS12990	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
C1N50_RS13015	COG1611	Belongs to the LOG family
C1N50_RS13035	COG2363	Small membrane protein
C1N50_RS13045	COG0583	DNA-binding transcription factor activity
C1N50_RS13060	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C1N50_RS13070	COG0142	geranyltranstransferase activity
C1N50_RS13080	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C1N50_RS13085	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C1N50_RS13110	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1N50_RS13110	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1N50_RS13115	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C1N50_RS13120	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C1N50_RS13135	COG1073	alpha beta
C1N50_RS13145	COG2252	PERMEase
C1N50_RS13150	COG2195	Cleaves the N-terminal amino acid of tripeptides
C1N50_RS13180	COG0047	phosphoribosylformylglycinamidine synthase activity
C1N50_RS13180	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C1N50_RS13195	COG0590	tRNA wobble adenosine to inosine editing
C1N50_RS13200	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C1N50_RS13220	COG4969	Belongs to the N-Me-Phe pilin family
C1N50_RS13240	COG1301	dicarboxylic acid transport
C1N50_RS13255	COG0497	DNA recombination
C1N50_RS13265	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1N50_RS13270	COG2914	Belongs to the UPF0125 (RnfH) family
C1N50_RS13275	COG2867	negative regulation of translational initiation
C1N50_RS13320	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C1N50_RS13340	COG0583	DNA-binding transcription factor activity
C1N50_RS13345	COG1289	transmembrane transporter activity
C1N50_RS13365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1N50_RS13380	COG0668	transmembrane transport
C1N50_RS13395	COG0583	DNA-binding transcription factor activity
C1N50_RS13405	COG1115	amino acid carrier protein
C1N50_RS13410	COG1584	GPR1 FUN34 yaaH family protein
C1N50_RS13420	COG1757	Na H antiporter
C1N50_RS13430	COG0516	GMP reductase activity
C1N50_RS13430	COG0517	IMP dehydrogenase activity
C1N50_RS13445	COG2203	Gaf domain
C1N50_RS13445	COG2199	diguanylate cyclase activity
C1N50_RS13460	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1N50_RS13465	COG2976	Protein conserved in bacteria
C1N50_RS13500	COG2975	iron-sulfur cluster assembly
C1N50_RS13505	COG0633	Ferredoxin
C1N50_RS13520	COG0316	Belongs to the HesB IscA family
C1N50_RS13525	COG0822	iron-sulfur transferase activity
C1N50_RS13540	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C1N50_RS13545	COG0483	inositol monophosphate 1-phosphatase activity
C1N50_RS13550	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N50_RS13555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N50_RS13560	COG1862	Preprotein translocase
C1N50_RS13585	COG0517	IMP dehydrogenase activity
C1N50_RS13595	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C1N50_RS13600	COG0583	DNA-binding transcription factor activity
C1N50_RS13605	COG0450	alkyl hydroperoxide reductase
C1N50_RS13635	COG0704	Plays a role in the regulation of phosphate uptake
C1N50_RS13640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C1N50_RS13645	COG0581	inorganic phosphate transmembrane transporter activity
C1N50_RS13650	COG0573	inorganic phosphate transmembrane transporter activity
C1N50_RS13655	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C1N50_RS13660	COG0248	Ppx GppA phosphatase
C1N50_RS13670	COG5002	protein histidine kinase activity
C1N50_RS13675	COG0745	RESPONSE REGULATOR receiver
C1N50_RS13685	COG0826	peptidase U32
C1N50_RS13690	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1N50_RS13755	COG0542	response to heat
C1N50_RS13760	COG1496	oxidoreductase activity
C1N50_RS13765	COG0564	pseudouridine synthase activity
C1N50_RS13770	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1N50_RS13775	COG0741	lytic transglycosylase activity
C1N50_RS13780	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C1N50_RS13785	COG0077	Prephenate dehydratase
C1N50_RS13785	COG1605	Chorismate mutase
C1N50_RS13790	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
C1N50_RS13805	COG0488	(ABC) transporter
C1N50_RS13815	COG0739	heme binding
C1N50_RS13820	COG0287	Prephenate dehydrogenase
C1N50_RS13820	COG1605	Chorismate mutase
C1N50_RS13825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1N50_RS13835	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C1N50_RS13855	COG1966	Carbon starvation protein
C1N50_RS13860	COG3275	phosphorelay sensor kinase activity
C1N50_RS13865	COG3279	Response regulator of the LytR AlgR family
C1N50_RS13870	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C1N50_RS13875	COG1047	Peptidyl-prolyl cis-trans
C1N50_RS13890	COG0196	riboflavin kinase activity
C1N50_RS13895	COG0728	peptidoglycan biosynthetic process
C1N50_RS13900	COG0268	Binds directly to 16S ribosomal RNA
C1N50_RS13905	COG0640	Transcriptional regulator
C1N50_RS13910	COG0583	DNA-binding transcription factor activity
C1N50_RS13915	COG1283	sodium-dependent phosphate transmembrane transporter activity
C1N50_RS13930	COG0730	response to heat
C1N50_RS13960	COG0667	Aldo Keto reductase
C1N50_RS13985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C1N50_RS13990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1N50_RS13995	COG4974	Belongs to the 'phage' integrase family
C1N50_RS14000	COG0716	FMN binding
C1N50_RS14015	COG0513	Belongs to the DEAD box helicase family
C1N50_RS14025	COG3022	response to hydroperoxide
C1N50_RS14030	COG1115	amino acid carrier protein
C1N50_RS14065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C1N50_RS14070	COG0083	homoserine kinase activity
C1N50_RS14085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C1N50_RS14100	COG0745	RESPONSE REGULATOR receiver
C1N50_RS14110	COG5002	protein histidine kinase activity
C1N50_RS14110	COG0784	Response regulator, receiver
C1N50_RS14110	COG2198	Histidine kinase
C1N50_RS14120	COG2203	Gaf domain
C1N50_RS14120	COG3706	GGDEF domain
C1N50_RS14120	COG4251	negative regulation of phosphorylation
C1N50_RS14120	COG5001	Diguanylate cyclase
C1N50_RS14125	COG1242	4 iron, 4 sulfur cluster binding
C1N50_RS14130	COG0067	glutamate synthase
C1N50_RS14130	COG0070	glutamate synthase
C1N50_RS14130	COG0069	glutamate synthase activity
C1N50_RS14140	COG0069	glutamate synthase activity
C1N50_RS14140	COG0070	glutamate synthase
C1N50_RS14140	COG0067	glutamate synthase
C1N50_RS14145	COG0493	'glutamate synthase
C1N50_RS14170	COG2860	membrane
C1N50_RS14175	COG0583	DNA-binding transcription factor activity
C1N50_RS14180	COG0730	response to heat
C1N50_RS14195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C1N50_RS14200	COG0505	Belongs to the CarA family
C1N50_RS14210	COG0494	nUDIX hydrolase
C1N50_RS14230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C1N50_RS14235	COG0849	cell division
C1N50_RS14240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C1N50_RS14255	COG0772	Belongs to the SEDS family
C1N50_RS14270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C1N50_RS14275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C1N50_RS14280	COG0768	penicillin binding
C1N50_RS14285	COG3116	cell division
C1N50_RS14310	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C1N50_RS14325	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C1N50_RS14330	COG2823	Periplasmic or secreted lipoprotein
C1N50_RS14335	COG2969	positive regulation of protein catabolic process
C1N50_RS14340	COG0625	glutathione transferase activity
C1N50_RS14345	COG2857	Cytochrome c1
C1N50_RS14350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C1N50_RS14355	COG0723	plastoquinol--plastocyanin reductase activity
C1N50_RS14375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C1N50_RS14385	COG3105	Protein conserved in bacteria
C1N50_RS14390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1N50_RS14395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1N50_RS14400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C1N50_RS14410	COG3150	esterase
C1N50_RS14420	COG3151	Protein conserved in bacteria
C1N50_RS14425	COG0494	nUDIX hydrolase
C1N50_RS14430	COG1538	Outer membrane efflux protein
C1N50_RS14440	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C1N50_RS14450	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C1N50_RS14455	COG3025	triphosphatase activity
C1N50_RS14460	COG1392	Phosphate transport regulator
C1N50_RS14465	COG0306	phosphate transporter
C1N50_RS14470	COG4991	sh3 domain protein
C1N50_RS14480	COG3267	Type II secretory pathway component ExeA
C1N50_RS14480	COG3409	Peptidoglycan-binding domain 1 protein
C1N50_RS14495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C1N50_RS14500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C1N50_RS14510	COG0596	Alpha beta hydrolase
C1N50_RS14515	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C1N50_RS14520	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C1N50_RS14525	COG1610	YqeY-like protein
C1N50_RS14530	COG0358	DNA primase activity
C1N50_RS14545	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C1N50_RS14595	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_RS14595	COG2213	PTS system mannitol-specific
C1N50_RS14605	COG3722	fumarate hydratase activity
C1N50_RS14610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1N50_RS14620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C1N50_RS14625	COG1349	DNA-binding transcription factor activity
C1N50_RS14630	COG0469	pyruvate kinase activity
C1N50_RS14640	COG3706	GGDEF domain
C1N50_RS14645	COG0440	acetolactate synthase activity
C1N50_RS14650	COG0028	Belongs to the TPP enzyme family
C1N50_RS14655	COG1022	Amp-dependent synthetase and ligase
C1N50_RS14660	COG0583	DNA-binding transcription factor activity
C1N50_RS14690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C1N50_RS14695	COG0473	3-isopropylmalate dehydrogenase activity
C1N50_RS14715	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C1N50_RS14720	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C1N50_RS14725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1N50_RS14730	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C1N50_RS14755	COG3610	response to peptide
C1N50_RS14760	COG2966	Psort location CytoplasmicMembrane, score
C1N50_RS14775	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C1N50_RS14780	COG0142	geranyltranstransferase activity
C1N50_RS14800	COG2358	TRAP transporter, solute receptor (TAXI family
C1N50_RS14815	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C1N50_RS14820	COG1178	ABC-type Fe3 transport system permease component
C1N50_RS14825	COG4143	(ABC) transporter
C1N50_RS14830	COG0163	prenyltransferase activity
C1N50_RS14835	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C1N50_RS14845	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C1N50_RS14860	COG2105	PFAM AIG2 family protein
C1N50_RS14870	COG0729	surface antigen
C1N50_RS14875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N50_RS14885	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C1N50_RS14900	COG1136	(ABC) transporter
C1N50_RS14920	COG0529	Catalyzes the synthesis of activated sulfate
C1N50_RS14925	COG0471	metal ion transport
C1N50_RS14925	COG3273	potassium ion transport
C1N50_RS14940	COG1648	precorrin-2 dehydrogenase activity
C1N50_RS14940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C1N50_RS14945	COG0737	Belongs to the 5'-nucleotidase family
C1N50_RS14955	COG0513	Belongs to the DEAD box helicase family
C1N50_RS14960	COG2153	protein acetylation
C1N50_RS14975	COG0545	Peptidyl-prolyl cis-trans isomerase
C1N50_RS14985	COG0203	ribosomal protein L17
C1N50_RS14990	COG0202	RNA polymerase activity
C1N50_RS15000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C1N50_RS15005	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C1N50_RS15010	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C1N50_RS15015	COG0201	protein transport
C1N50_RS15025	COG1841	ribosomal large subunit assembly
C1N50_RS15110	COG0088	Forms part of the polypeptide exit tunnel
C1N50_RS15130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C1N50_RS15135	COG1609	Transcriptional regulator
C1N50_RS15160	COG1575	Belongs to the MenA family. Type 1 subfamily
C1N50_RS15165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C1N50_RS15180	COG1494	fructose-1,6-bisphosphatase
C1N50_RS15210	COG0149	triose-phosphate isomerase activity
C1N50_RS15235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C1N50_RS15245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C1N50_RS15250	COG0438	transferase activity, transferring glycosyl groups
C1N50_RS15255	COG0438	transferase activity, transferring glycosyl groups
C1N50_RS15280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C1N50_RS15285	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C1N50_RS15290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C1N50_RS15295	COG1216	Glycosyl transferase, family 2
C1N50_RS15295	COG0463	Glycosyl transferase, family 2
C1N50_RS15330	COG1083	cytidylyl-transferase
C1N50_RS15335	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1N50_RS15345	COG2089	acid synthase
C1N50_RS15350	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C1N50_RS15355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C1N50_RS15395	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1N50_RS15405	COG1560	Kdo2-lipid A biosynthetic process
C1N50_RS15410	COG0859	PFAM glycosyl transferase family 9
C1N50_RS15415	COG1519	Transferase
C1N50_RS15430	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_RS15475	COG3642	lipopolysaccharide core region biosynthetic process
C1N50_RS15480	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C1N50_RS15485	COG0438	transferase activity, transferring glycosyl groups
C1N50_RS15490	COG0859	PFAM glycosyl transferase family 9
C1N50_RS15550	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C1N50_RS15560	COG1560	Kdo2-lipid A biosynthetic process
C1N50_RS15565	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C1N50_RS15570	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C1N50_RS15575	COG1561	YicC-like family, N-terminal region
C1N50_RS15595	COG4608	Belongs to the ABC transporter superfamily
C1N50_RS15600	COG0444	Belongs to the ABC transporter superfamily
C1N50_RS15605	COG0747	negative chemotaxis
C1N50_RS15610	COG4239	(ABC) transporter, permease
C1N50_RS15615	COG4174	ABC transporter (Permease)
C1N50_RS15620	COG4206	TonB-dependent receptor
C1N50_RS15635	COG0811	peptide transport
C1N50_RS15640	COG0848	biopolymer transport protein
C1N50_RS15660	COG0194	GDP metabolic process
C1N50_RS15665	COG1758	RNA polymerase activity
C1N50_RS15670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C1N50_RS15675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1N50_RS15680	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C1N50_RS15690	COG2233	PERMEase
C1N50_RS15705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1N50_RS15715	COG2183	response to ionizing radiation
C1N50_RS15730	COG1040	competence protein
C1N50_RS15740	COG0494	nUDIX hydrolase
C1N50_RS15745	COG1218	3'(2'),5'-bisphosphate nucleotidase
C1N50_RS15755	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C1N50_RS15760	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C1N50_RS15765	COG3156	type II secretion system protein K
C1N50_RS15770	COG4795	General secretion pathway protein
C1N50_RS15775	COG2165	general secretion pathway protein
C1N50_RS15780	COG2165	general secretion pathway protein
C1N50_RS15785	COG2165	general secretion pathway protein
C1N50_RS15790	COG1459	type II secretion system
C1N50_RS15795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1N50_RS15805	COG3031	protein transport across the cell outer membrane
C1N50_RS15810	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C1N50_RS15830	COG0456	acetyltransferase
C1N50_RS15835	COG1490	D-aminoacyl-tRNA deacylase activity
C1N50_RS15855	COG1217	gtp-binding protein TYPA
C1N50_RS15865	COG0174	glutamine synthetase
C1N50_RS15875	COG3852	Histidine kinase
C1N50_RS15880	COG2204	response regulator
C1N50_RS15885	COG3300	MHYT domain
C1N50_RS15885	COG5001	Diguanylate cyclase
C1N50_RS15890	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C1N50_RS15925	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C1N50_RS15935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1N50_RS15935	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1N50_RS15955	COG0084	hydrolase, TatD family'
C1N50_RS15960	COG0805	protein transport
C1N50_RS15965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C1N50_RS15980	COG3165	ubiquinone biosynthetic process from chorismate
C1N50_RS15990	COG1322	Protein conserved in bacteria
C1N50_RS16005	COG1910	domain protein
C1N50_RS16025	COG2081	HI0933 family
C1N50_RS16035	COG1528	Iron-storage protein
C1N50_RS16040	COG0589	response to stress
C1N50_RS16060	COG5002	protein histidine kinase activity
C1N50_RS16060	COG5001	Diguanylate cyclase
C1N50_RS16065	COG1522	sequence-specific DNA binding
C1N50_RS16080	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C1N50_RS16090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1N50_RS16095	COG0800	Aldolase
C1N50_RS16100	COG2610	gluconate transmembrane transporter activity
C1N50_RS16105	COG3265	gluconokinase activity
C1N50_RS16110	COG0129	dihydroxy-acid dehydratase activity
C1N50_RS16120	COG2076	Multidrug Resistance protein
C1N50_RS16125	COG0583	DNA-binding transcription factor activity
C1N50_RS16130	COG1609	Transcriptional regulator
C1N50_RS16135	COG0515	serine threonine protein kinase
C1N50_RS16165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N50_RS16170	COG0601	transmembrane transport
C1N50_RS16175	COG4166	transmembrane transport
C1N50_RS16180	COG4172	Belongs to the ABC transporter superfamily
C1N50_RS16230	COG1309	transcriptional regulator
C1N50_RS16235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N50_RS16240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N50_RS16250	COG2960	long-chain fatty acid transporting porin activity
C1N50_RS16255	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C1N50_RS16260	COG0583	DNA-binding transcription factor activity
C1N50_RS16315	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C1N50_RS16340	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C1N50_RS16345	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C1N50_RS16350	COG0551	DNA topoisomerase type I activity
C1N50_RS16360	COG0758	DNA mediated transformation
C1N50_RS16370	COG0242	peptide deformylase activity
C1N50_RS16380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C1N50_RS16380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C1N50_RS16385	COG0569	domain protein
C1N50_RS16390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N50_RS16400	COG1272	protein, Hemolysin III
C1N50_RS16405	COG4326	sporulation control protein
C1N50_RS16415	COG3084	Protein conserved in bacteria
C1N50_RS16425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C1N50_RS16430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1N50_RS16435	COG0204	Acyl-transferase
C1N50_RS16445	COG2199	diguanylate cyclase activity
C1N50_RS16450	COG0606	chelatase, subunit chli
C1N50_RS16460	COG3978	acetolactate synthase activity
C1N50_RS16465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C1N50_RS16470	COG0129	dihydroxy-acid dehydratase activity
C1N50_RS16480	COG0583	DNA-binding transcription factor activity
C1N50_RS16485	COG2814	Major facilitator Superfamily
C1N50_RS16490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N50_RS16495	COG0765	amino acid transport
C1N50_RS16505	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C1N50_RS16515	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C1N50_RS16545	COG3312	ion transport
C1N50_RS16550	COG1475	DNA binding
C1N50_RS16555	COG1192	Involved in chromosome partitioning
C1N50_RS16570	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C1N50_RS16600	COG1126	abc transporter atp-binding protein
C1N50_RS16625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C1N50_RS16635	COG0584	glycerophosphoryl diester phosphodiesterase
C1N50_RS16640	COG0745	RESPONSE REGULATOR receiver
C1N50_RS16660	COG0811	peptide transport
C1N50_RS16665	COG0811	peptide transport
C1N50_RS16670	COG0848	biopolymer transport protein
C1N50_RS16715	COG0803	Belongs to the bacterial solute-binding protein 9 family
C1N50_RS16720	COG1121	(ABC) transporter
C1N50_RS16725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1N50_RS16740	COG1770	oligopeptidase
C1N50_RS16745	COG2814	Major facilitator Superfamily
C1N50_RS16750	COG0010	Belongs to the arginase family
C1N50_RS16755	COG1166	arginine decarboxylase activity
C1N50_RS16765	COG0189	ligase activity
C1N50_RS16765	COG4067	protein conserved in archaea
C1N50_RS16770	COG0189	ligase activity
C1N50_RS16780	COG0583	DNA-binding transcription factor activity
C1N50_RS16820	COG1114	Component of the transport system for branched-chain amino acids
C1N50_RS16840	COG0579	oxidoreductase
C1N50_RS16845	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C1N50_RS16860	COG3033	Beta-eliminating lyase
C1N50_RS16880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1N50_RS16885	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1N50_RS16920	COG3706	GGDEF domain
C1N50_RS16925	COG0415	Belongs to the DNA photolyase family
C1N50_RS16930	COG3046	protein related to deoxyribodipyrimidine photolyase
C1N50_RS16945	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N50_RS16945	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N50_RS16950	COG1765	OsmC-like protein
C1N50_RS16985	COG1011	Hydrolase
C1N50_RS17010	COG3240	lipase activity
C1N50_RS17030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C1N50_RS17040	COG1840	ABC-type Fe3 transport system, periplasmic component
C1N50_RS17050	COG3842	ATPase activity
C1N50_RS17075	COG2990	Protein conserved in bacteria
C1N50_RS17085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1N50_RS17090	COG2866	Carboxypeptidase
C1N50_RS17100	COG0583	DNA-binding transcription factor activity
C1N50_RS17125	COG3104	oligopeptide transport
C1N50_RS17130	COG1760	l-serine dehydratase
C1N50_RS17155	COG1388	LysM domain
C1N50_RS17155	COG0741	lytic transglycosylase activity
C1N50_RS17175	COG1815	bacterial-type flagellum-dependent cell motility
C1N50_RS17180	COG1558	bacterial-type flagellum-dependent cell motility
C1N50_RS17185	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C1N50_RS17190	COG1749	Flagellar hook protein flgE
C1N50_RS17195	COG4787	bacterial-type flagellum-dependent cell motility
C1N50_RS17200	COG4786	Flagellar basal body rod
C1N50_RS17205	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C1N50_RS17210	COG1706	bacterial-type flagellum-dependent cell motility
C1N50_RS17220	COG1256	bacterial-type flagellum assembly
C1N50_RS17220	COG4786	Flagellar basal body rod
C1N50_RS17225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_RS17290	COG0384	phenazine biosynthesis protein PhzF
C1N50_RS17300	COG1360	Flagellar Motor Protein
C1N50_RS17305	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C1N50_RS17310	COG1191	sigma factor activity
C1N50_RS17315	COG1580	Controls the rotational direction of flagella during chemotaxis
C1N50_RS17330	COG1516	flagellar protein fliS
C1N50_RS17335	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C1N50_RS17345	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N50_RS17360	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C1N50_RS17370	COG1987	bacterial-type flagellum assembly
C1N50_RS17430	COG2200	EAL domain
C1N50_RS17475	COG0346	lactoylglutathione lyase activity
C1N50_RS17500	COG0745	RESPONSE REGULATOR receiver
C1N50_RS17525	COG0156	8-amino-7-oxononanoate synthase activity
C1N50_RS17530	COG1063	alcohol dehydrogenase
C1N50_RS17555	COG2199	diguanylate cyclase activity
C1N50_RS17555	COG2203	Gaf domain
C1N50_RS17560	COG2223	nitrite transmembrane transporter activity
C1N50_RS17565	COG1063	alcohol dehydrogenase
C1N50_RS17575	COG0668	transmembrane transport
C1N50_RS17585	COG1304	FMN binding
C1N50_RS17590	COG1620	l-lactate permease
C1N50_RS17595	COG0583	DNA-binding transcription factor activity
C1N50_RS17600	COG1505	serine-type exopeptidase activity
C1N50_RS17605	COG4172	Belongs to the ABC transporter superfamily
C1N50_RS17615	COG1067	ATP-dependent peptidase activity
C1N50_RS17625	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C1N50_RS17645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N50_RS17665	COG1122	ATPase activity
C1N50_RS17675	COG1566	PFAM secretion protein HlyD family protein
C1N50_RS17705	COG0813	purine-nucleoside phosphorylase activity
C1N50_RS17715	COG3272	Protein of unknown function (DUF1722)
C1N50_RS17720	COG0789	Transcriptional regulator
C1N50_RS17725	COG0415	Belongs to the DNA photolyase family
C1N50_RS17730	COG1388	LysM domain
C1N50_RS17730	COG1376	ErfK ybiS ycfS ynhG family protein
C1N50_RS17740	COG0513	Belongs to the DEAD box helicase family
C1N50_RS17745	COG1770	oligopeptidase
C1N50_RS17750	COG4771	TonB-dependent receptor
C1N50_RS17770	COG0840	transmembrane signaling receptor activity
C1N50_RS17780	COG0573	inorganic phosphate transmembrane transporter activity
C1N50_RS17785	COG0581	inorganic phosphate transmembrane transporter activity
C1N50_RS17790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C1N50_RS17825	COG0714	Associated with various cellular activities
C1N50_RS17845	COG2197	response regulator
C1N50_RS17870	COG0110	maltose O-acetyltransferase activity
C1N50_RS17880	COG4191	Histidine kinase
C1N50_RS17885	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_RS17920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C1N50_RS17925	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
C1N50_RS17935	COG1252	NADH dehydrogenase
C1N50_RS17940	COG1301	dicarboxylic acid transport
C1N50_RS17945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1N50_RS17975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N50_RS17975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_RS17975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N50_RS17980	COG2207	Transcriptional regulator
C1N50_RS17990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N50_RS17995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N50_RS18005	COG2084	Dehydrogenase
C1N50_RS18010	COG0753	catalase activity
C1N50_RS18020	COG2130	NADP-dependent
C1N50_RS18025	COG1309	transcriptional regulator
C1N50_RS18070	COG3206	protein involved in exopolysaccharide biosynthesis
C1N50_RS18070	COG0489	protein tyrosine kinase activity
C1N50_RS18085	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C1N50_RS18090	COG2200	EAL domain
C1N50_RS18125	COG3842	ATPase activity
C1N50_RS18140	COG1175	transmembrane transport
C1N50_RS18145	COG3833	ABC-type maltose transport systems, permease component
C1N50_RS18175	COG2354	Protein conserved in bacteria
C1N50_RS18190	COG0401	homolog of Blt101
C1N50_RS18195	COG3217	Mosc domain protein beta barrel domain protein
C1N50_RS18195	COG0633	Ferredoxin
C1N50_RS18195	COG0633	Ferredoxin
C1N50_RS18195	COG3217	Mosc domain protein beta barrel domain protein
C1N50_RS18205	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C1N50_RS18245	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
C1N50_RS18250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N50_RS18260	COG0848	biopolymer transport protein
C1N50_RS18265	COG0811	peptide transport
C1N50_RS18270	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C1N50_RS18280	COG3721	Heme iron utilization protein
C1N50_RS18285	COG0748	coenzyme F420 binding
C1N50_RS18300	COG0784	Response regulator, receiver
C1N50_RS18300	COG0835	chemotaxis
C1N50_RS18305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1N50_RS18310	COG0366	Alpha amylase catalytic
C1N50_RS18345	COG0583	DNA-binding transcription factor activity
C1N50_RS18360	COG2249	NAD(P)H dehydrogenase (quinone) activity
C1N50_RS18365	COG0583	DNA-binding transcription factor activity
C1N50_RS18385	COG2814	Major facilitator Superfamily
C1N50_RS18395	COG4977	sequence-specific DNA binding
C1N50_RS18405	COG2194	sulfuric ester hydrolase activity
C1N50_RS18410	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C1N50_RS18420	COG2205	protein histidine kinase activity
C1N50_RS18425	COG0745	RESPONSE REGULATOR receiver
C1N50_RS18430	COG4221	oxidoreductase activity
C1N50_RS18445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1N50_RS18465	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C1N50_RS18475	COG2814	Major facilitator Superfamily
C1N50_RS18490	COG1418	mRNA catabolic process
C1N50_RS18505	COG0402	S-adenosylhomocysteine deaminase activity
C1N50_RS18510	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C1N50_RS18515	COG2239	Acts as a magnesium transporter
C1N50_RS18520	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C1N50_RS18525	COG1566	PFAM secretion protein HlyD family protein
C1N50_RS18550	COG0745	RESPONSE REGULATOR receiver
C1N50_RS18555	COG2205	protein histidine kinase activity
C1N50_RS18565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N50_RS18570	COG0531	amino acid
C1N50_RS18585	COG0583	DNA-binding transcription factor activity
C1N50_RS18605	COG0784	Response regulator, receiver
C1N50_RS18605	COG5002	protein histidine kinase activity
C1N50_RS18605	COG2205	protein histidine kinase activity
C1N50_RS18610	COG0673	inositol 2-dehydrogenase activity
C1N50_RS18690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N50_RS18695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N50_RS18705	COG1280	lysine exporter protein (LysE YggA)
C1N50_RS18715	COG0183	Belongs to the thiolase family
C1N50_RS18740	COG3005	denitrification pathway
C1N50_RS18760	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1N50_RS18765	COG3850	Histidine kinase
C1N50_RS18770	COG2197	response regulator
C1N50_RS18785	COG2195	Cleaves the N-terminal amino acid of tripeptides
C1N50_RS18810	COG0840	transmembrane signaling receptor activity
C1N50_RS18820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1N50_RS18825	COG0545	Peptidyl-prolyl cis-trans isomerase
C1N50_RS18855	COG1278	Cold shock
C1N50_RS18860	COG3036	rescue of stalled ribosome
C1N50_RS18870	COG2199	diguanylate cyclase activity
C1N50_RS18890	COG1136	(ABC) transporter
C1N50_RS18900	COG0840	transmembrane signaling receptor activity
C1N50_RS18905	COG0783	Belongs to the Dps family
C1N50_RS18915	COG1619	proteins homologs of microcin C7 resistance protein MccF
C1N50_RS18920	COG2133	pyrroloquinoline quinone binding
C1N50_RS18925	COG1454	alcohol dehydrogenase
C1N50_RS18930	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C1N50_RS18950	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1N50_RS18960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1N50_RS18965	COG3186	Phenylalanine-4-hydroxylase
C1N50_RS19000	COG3530	Putative quorum-sensing-regulated virulence factor
C1N50_RS19010	COG0454	-acetyltransferase
C1N50_RS19040	COG0523	cobalamin synthesis protein
C1N50_RS19050	COG0513	Belongs to the DEAD box helicase family
C1N50_RS19070	COG2200	EAL domain
C1N50_RS19075	COG1119	ATPase activity
C1N50_RS19105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C1N50_RS19120	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
C1N50_RS19125	COG0513	Belongs to the DEAD box helicase family
C1N50_RS19130	COG5001	Diguanylate cyclase
C1N50_RS19140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C1N50_RS19155	COG3278	Belongs to the heme-copper respiratory oxidase family
C1N50_RS19200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C1N50_RS19205	COG1960	acyl-CoA dehydrogenase activity
C1N50_RS19215	COG0183	Belongs to the thiolase family
C1N50_RS19230	COG1024	Enoyl-CoA hydratase
C1N50_RS19235	COG1024	Enoyl-CoA hydratase
C1N50_RS19245	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_RS19250	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C1N50_RS19255	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C1N50_RS19260	COG1845	cytochrome c oxidase, subunit III
C1N50_RS19265	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C1N50_RS19275	COG1902	pentaerythritol trinitrate reductase activity
C1N50_RS19275	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1N50_RS19290	COG1012	belongs to the aldehyde dehydrogenase family
C1N50_RS19300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1N50_RS19350	COG1126	abc transporter atp-binding protein
C1N50_RS19355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N50_RS19360	COG4215	(ABC) transporter
C1N50_RS19365	COG4160	amino acid transport
C1N50_RS19390	COG2200	EAL domain
C1N50_RS19440	COG0443	Heat shock 70 kDa protein
C1N50_RS19475	COG0745	RESPONSE REGULATOR receiver
C1N50_RS19490	COG1785	Belongs to the alkaline phosphatase family
C1N50_RS19520	COG0814	amino acid
C1N50_RS19525	COG0456	acetyltransferase
C1N50_RS19530	COG0243	molybdopterin cofactor binding
C1N50_RS19535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C1N50_RS19535	COG1648	precorrin-2 dehydrogenase activity
C1N50_RS19560	COG1116	anion transmembrane transporter activity
C1N50_RS19560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C1N50_RS19565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N50_RS19570	COG1116	anion transmembrane transporter activity
C1N50_RS19575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1N50_RS19575	COG2146	nitrite reductase [NAD(P)H] activity
C1N50_RS19615	COG1902	pentaerythritol trinitrate reductase activity
C1N50_RS19625	COG0739	heme binding
C1N50_RS19635	COG3038	cytochrome b561
C1N50_RS19730	COG2814	Major facilitator Superfamily
C1N50_RS19735	COG1280	lysine exporter protein (LysE YggA)
C1N50_RS19775	COG1132	(ABC) transporter
C1N50_RS19785	COG5640	endopeptidase activity
C1N50_RS19805	COG0583	DNA-binding transcription factor activity
C1N50_RS19840	COG1120	ATPase activity
C1N50_RS19845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N50_RS19850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N50_RS19855	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C1N50_RS19950	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_RS19955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N50_RS19960	COG1720	tRNA m6t6A37 methyltransferase activity
C1N50_RS19990	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C1N50_RS20000	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C1N50_RS20010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N50_RS20015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N50_RS20030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N50_RS20030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N50_RS20030	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C1N50_RS20035	COG1105	Belongs to the carbohydrate kinase PfkB family
C1N50_RS20040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_RS20040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_RS20045	COG1609	Transcriptional regulator
C1N50_RS20060	COG2200	EAL domain
C1N50_RS20060	COG2199	diguanylate cyclase activity
C1N50_RS20060	COG2203	Gaf domain
C1N50_RS20065	COG0765	amino acid transport
C1N50_RS20070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N50_RS20075	COG0765	amino acid transport
C1N50_RS20080	COG1126	abc transporter atp-binding protein
C1N50_RS20090	COG1979	alcohol dehydrogenase
C1N50_RS20095	COG2207	Transcriptional regulator
C1N50_RS20110	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1N50_RS20120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N50_RS20135	COG0784	Response regulator, receiver
C1N50_RS20135	COG3437	response regulator, receiver
C1N50_RS20140	COG0546	phosphoglycolate phosphatase activity
C1N50_RS20160	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
C1N50_RS20165	COG0513	Belongs to the DEAD box helicase family
C1N50_RS20170	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C1N50_RS20185	COG3038	cytochrome b561
C1N50_RS20195	COG2116	formate transmembrane transporter activity
C1N50_RS20205	COG0583	DNA-binding transcription factor activity
C1N50_RS20215	COG3593	DNA synthesis involved in DNA repair
C1N50_RS20220	COG0737	Belongs to the 5'-nucleotidase family
C1N50_RS20225	COG0861	Integral membrane protein TerC family
C1N50_RS20235	COG0646	methionine synthase
C1N50_RS20235	COG1410	methionine synthase
C1N50_RS20250	COG2267	carboxylic ester hydrolase activity
C1N50_RS20255	COG2067	long-chain fatty acid transport protein
C1N50_RS20265	COG0501	Belongs to the peptidase M48B family
C1N50_RS20270	COG2050	protein possibly involved in aromatic compounds catabolism
C1N50_RS20305	COG0484	heat shock protein binding
C1N50_RS20315	COG5001	Diguanylate cyclase
C1N50_RS20315	COG3300	MHYT domain
C1N50_RS20320	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C1N50_RS20330	COG4181	ATPase activity
C1N50_RS20335	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C1N50_RS20345	COG1984	allophanate hydrolase subunit 2
C1N50_RS20350	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C1N50_RS20360	COG3447	MASE1 domain protein
C1N50_RS20360	COG5002	protein histidine kinase activity
C1N50_RS20360	COG5001	Diguanylate cyclase
C1N50_RS20365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1N50_RS20375	COG1629	transport
C1N50_RS20375	COG4771	TonB-dependent receptor
C1N50_RS20380	COG0583	DNA-binding transcription factor activity
C1N50_RS20385	COG1042	CoA-binding domain protein
C1N50_RS20385	COG0045	succinate-CoA ligase (ADP-forming) activity
C1N50_RS20385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N50_RS20405	COG0023	Translation Initiation Factor
C1N50_RS20540	COG3140	Belongs to the UPF0181 family
C1N50_RS20565	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C1N50_RS20570	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C1N50_RS20590	COG2203	Gaf domain
C1N50_RS20590	COG3706	GGDEF domain
C1N50_RS20590	COG4251	negative regulation of phosphorylation
C1N50_RS20590	COG5001	Diguanylate cyclase
C1N50_RS20600	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C1N50_RS20605	COG4149	molybdate abc transporter
C1N50_RS20610	COG0725	ABC transporter, periplasmic molybdate-binding protein
C1N50_RS20620	COG3111	PFAM Bacterial OB fold (BOF) protein
C1N50_RS20645	COG0534	Mate efflux family protein
C1N50_RS20650	COG0602	queuosine metabolic process
C1N50_RS20655	COG1328	CTP reductase activity
C1N50_RS20720	COG2197	response regulator
C1N50_RS20725	COG3851	Histidine kinase
C1N50_RS20730	COG2271	Major facilitator Superfamily
C1N50_RS20735	COG1482	cell wall glycoprotein biosynthetic process
C1N50_RS20745	COG0628	permease
C1N50_RS20755	COG1566	PFAM secretion protein HlyD family protein
C1N50_RS20780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1N50_RS20785	COG3118	belongs to the thioredoxin family
C1N50_RS20820	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C1N50_RS20840	COG2116	formate transmembrane transporter activity
C1N50_RS20850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1N50_RS20860	COG2199	diguanylate cyclase activity
C1N50_RS20915	COG0277	FAD linked oxidase domain protein
C1N50_RS20920	COG0583	DNA-binding transcription factor activity
C1N50_RS20925	COG1472	Belongs to the glycosyl hydrolase 3 family
C1N50_RS20935	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C1N50_RS20950	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C1N50_RS20960	COG1288	antiporter activity
C1N50_RS20970	COG3040	lipid binding
C1N50_RS21000	COG3469	chitinase activity
C1N50_RS21010	COG0419	ATPase involved in DNA repair
C1N50_RS21015	COG0420	3'-5' exonuclease activity
C1N50_RS21025	COG3209	COG3209 Rhs family protein
C1N50_RS21095	COG0631	protein serine/threonine phosphatase activity
C1N50_RS21130	COG0515	serine threonine protein kinase
C1N50_RS21130	COG2815	serine threonine protein kinase
C1N50_RS21160	COG0346	lactoylglutathione lyase activity
C1N50_RS21165	COG1902	pentaerythritol trinitrate reductase activity
C1N50_RS21175	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C1N50_RS21175	COG2755	lipolytic protein G-D-S-L family
C1N50_RS21185	COG5642	Protein of unknown function (DUF2384)
C1N50_RS21200	COG1234	tRNA 3'-trailer cleavage
C1N50_RS21205	COG2067	long-chain fatty acid transport protein
C1N50_RS21255	COG0671	phosphoesterase, PA-phosphatase related
C1N50_RS21275	COG2962	Rard protein
C1N50_RS21285	COG2165	general secretion pathway protein
C1N50_RS21290	COG0784	Response regulator, receiver
C1N50_RS21290	COG0835	chemotaxis
C1N50_RS21295	COG0778	Nitroreductase
C1N50_RS21300	COG2197	response regulator
C1N50_RS21325	COG4771	TonB-dependent receptor
C1N50_RS21390	COG1522	sequence-specific DNA binding
C1N50_RS21425	COG0515	serine threonine protein kinase
C1N50_RS21450	COG3501	Rhs element vgr protein
C1N50_RS21465	COG2204	response regulator
C1N50_RS21490	COG0739	heme binding
C1N50_RS21495	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C1N50_RS21525	COG3069	C4-dicarboxylate transmembrane transporter activity
C1N50_RS21530	COG1704	LemA family
C1N50_RS21535	COG0501	Belongs to the peptidase M48B family
C1N50_RS21560	COG0641	radical SAM
C1N50_RS21580	COG3111	PFAM Bacterial OB fold (BOF) protein
C1N50_RS21585	COG1597	lipid kinase activity
C1N50_RS21590	COG0583	DNA-binding transcription factor activity
C1N50_RS21595	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1N50_RS21595	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1N50_RS21600	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C1N50_RS21610	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C1N50_RS21670	COG0714	Associated with various cellular activities
C1N50_RS21675	COG3063	Type IV pilus biogenesis stability protein PilW
C1N50_RS21680	COG3119	arylsulfatase activity
C1N50_RS21685	COG3119	arylsulfatase activity
C1N50_RS21715	COG0784	Response regulator, receiver
C1N50_RS21715	COG2205	protein histidine kinase activity
C1N50_RS21715	COG2198	Histidine kinase
C1N50_RS21720	COG1879	ABC-type sugar transport system periplasmic component
C1N50_RS21730	COG0210	DNA helicase
C1N50_RS21735	COG1289	transmembrane transporter activity
C1N50_RS21760	COG0789	Transcriptional regulator
C1N50_RS21765	COG4604	ABC transporter, ATP-binding protein
C1N50_RS21770	COG4605	iron ion homeostasis
C1N50_RS21775	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N50_RS21780	COG4607	ABC-type enterochelin transport system periplasmic component
C1N50_RS21795	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C1N50_RS21810	COG1609	Transcriptional regulator
C1N50_RS21815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N50_RS21825	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1N50_RS21830	COG1129	ABC transporter
C1N50_RS21840	COG5001	Diguanylate cyclase
C1N50_RS21845	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C1N50_RS21870	COG0586	Pfam SNARE associated Golgi protein
C1N50_RS21915	COG0784	Response regulator, receiver
C1N50_RS21915	COG2205	protein histidine kinase activity
C1N50_RS21945	COG0330	HflC and HflK could
C1N50_RS21955	COG0517	IMP dehydrogenase activity
C1N50_RS21955	COG4175	Glycine betaine
C1N50_RS21960	COG4176	ABC-type proline glycine betaine transport system permease component
C1N50_RS21985	COG3706	GGDEF domain
C1N50_RS21995	COG0402	S-adenosylhomocysteine deaminase activity
C1N50_RS22005	COG2885	chlorophyll binding
C1N50_RS22045	COG0455	bacterial-type flagellum organization
C1N50_RS22055	COG4964	Belongs to the GSP D family
C1N50_RS22075	COG0583	DNA-binding transcription factor activity
C1N50_RS22080	COG1073	alpha beta
C1N50_RS22095	COG2801	Transposase and inactivated derivatives
C1N50_RS22115	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C1N50_RS22115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C1N50_RS22130	COG4989	oxidoreductase activity
C1N50_RS22155	COG1914	H( )-stimulated, divalent metal cation uptake system
C1N50_RS22170	COG0303	'Molybdopterin
C1N50_RS22225	COG2897	thiosulfate sulfurtransferase activity
C1N50_RS22230	COG2199	diguanylate cyclase activity
C1N50_RS22230	COG2202	Pas domain
C1N50_RS22230	COG2200	EAL domain
C1N50_RS22255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C1N50_RS22260	COG0840	transmembrane signaling receptor activity
C1N50_RS22265	COG2814	Major facilitator Superfamily
C1N50_RS22270	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1N50_RS22285	COG1612	heme a metabolic process
C1N50_RS22305	COG1845	cytochrome c oxidase, subunit III
C1N50_RS22310	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
C1N50_RS22315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C1N50_RS22325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1N50_RS22335	COG1280	lysine exporter protein (LysE YggA)
C1N50_RS22355	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1N50_RS22370	COG0697	spore germination
C1N50_RS22390	COG2814	Major facilitator Superfamily
C1N50_RS22395	COG0583	DNA-binding transcription factor activity
C1N50_RS22400	COG5001	Diguanylate cyclase
C1N50_RS22405	COG0739	heme binding
C1N50_RS22430	COG3314	Sporulation integral membrane protein YlbJ
C1N50_RS22445	COG0814	amino acid
C1N50_RS22465	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C1N50_RS22470	COG1072	(Pantothenic acid kinase))
C1N50_RS22480	COG1063	alcohol dehydrogenase
C1N50_RS22485	COG2213	PTS system mannitol-specific
C1N50_RS22490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N50_RS22495	COG0747	negative chemotaxis
C1N50_RS22505	COG1733	regulation of RNA biosynthetic process
C1N50_RS22520	COG0798	PFAM Bile acid sodium symporter
C1N50_RS22535	COG1881	PFAM PEBP family protein
C1N50_RS22545	COG0251	oxidation-reduction process
C1N50_RS22550	COG2706	6-phosphogluconolactonase activity
C1N50_RS22560	COG0800	Aldolase
C1N50_RS22565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N50_RS22570	COG4145	pantothenate transmembrane transporter activity
C1N50_RS22580	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
C1N50_RS22605	COG1131	(ABC) transporter
C1N50_RS22610	COG0842	Transport permease protein
C1N50_RS22630	COG3383	formate dehydrogenase (NAD+) activity
C1N50_RS22650	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N50_RS22660	COG1280	lysine exporter protein (LysE YggA)
C1N50_RS22665	COG0583	DNA-binding transcription factor activity
C1N50_RS22680	COG0494	nUDIX hydrolase
C1N50_RS22695	COG1858	cytochrome C peroxidase
C1N50_RS22725	COG1505	serine-type exopeptidase activity
C1N50_RS22730	COG0488	(ABC) transporter
C1N50_RS22740	COG0589	response to stress
C1N50_RS22750	COG0584	glycerophosphoryl diester phosphodiesterase
C1N50_RS22760	COG1175	transmembrane transport
C1N50_RS22765	COG0395	ABC-type sugar transport system, permease component
C1N50_RS22770	COG3842	ATPase activity
C1N50_RS22795	COG0523	cobalamin synthesis protein
C1N50_RS22805	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C1N50_RS22815	COG4667	esterase of the alpha-beta hydrolase superfamily
C1N50_RS22820	COG1741	Belongs to the pirin family
C1N50_RS22825	COG1278	Cold shock
C1N50_RS22840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C1N50_RS22865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1N50_RS22875	COG1686	Belongs to the peptidase S11 family
C1N50_RS22880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1N50_RS22885	COG0625	glutathione transferase activity
C1N50_RS22895	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C1N50_RS22950	COG0583	DNA-binding transcription factor activity
C1N50_RS22960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1N50_RS22965	COG1917	Cupin 2, conserved barrel domain protein
C1N50_RS22965	COG2207	Transcriptional regulator
C1N50_RS23020	COG0745	RESPONSE REGULATOR receiver
C1N50_RS23030	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_RS23055	COG3746	phosphate-selective porin O and P
C1N50_RS23075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N50_RS23120	COG0513	Belongs to the DEAD box helicase family
C1N50_RS23130	COG0583	DNA-binding transcription factor activity
C1N50_RS23150	COG1902	pentaerythritol trinitrate reductase activity
C1N50_RS23160	COG3853	Toxic anion resistance protein (TelA)
C1N50_RS23170	COG2255	four-way junction helicase activity
C1N50_RS23185	COG3122	Protein conserved in bacteria
C1N50_RS23190	COG2321	neutral zinc metallopeptidase
C1N50_RS23205	COG0583	DNA-binding transcription factor activity
C1N50_RS23210	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C1N50_RS23225	COG0252	asparaginase activity
C1N50_RS23235	COG0574	Belongs to the PEP-utilizing enzyme family
C1N50_RS23235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1N50_RS23245	COG2197	response regulator
C1N50_RS23250	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C1N50_RS23260	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C1N50_RS23265	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C1N50_RS23300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1N50_RS23305	COG0318	PFAM AMP-dependent synthetase and ligase
C1N50_RS23335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N50_RS23345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1N50_RS23385	COG4948	Mandelate Racemase Muconate Lactonizing
C1N50_RS23405	COG1342	Belongs to the UPF0251 family
C1N50_RS23415	COG4176	ABC-type proline glycine betaine transport system permease component
C1N50_RS23420	COG3448	diguanylate cyclase activity
C1N50_RS23420	COG4175	Glycine betaine
C1N50_RS23435	COG0583	DNA-binding transcription factor activity
C1N50_RS23445	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C1N50_RS23480	COG1335	isochorismatase
C1N50_RS23495	COG0753	catalase activity
C1N50_RS23510	COG1349	DNA-binding transcription factor activity
C1N50_RS23515	COG0346	lactoylglutathione lyase activity
C1N50_RS23520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N50_RS23520	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N50_RS23530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N50_RS23535	COG3537	Alpha-1,2-mannosidase
C1N50_RS23540	COG3537	Alpha-1,2-mannosidase
C1N50_RS23550	COG3537	Alpha-1,2-mannosidase
C1N50_RS23555	COG3537	Alpha-1,2-mannosidase
C1N50_RS23570	COG1280	lysine exporter protein (LysE YggA)
C1N50_RS23575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N50_RS23585	COG0583	DNA-binding transcription factor activity
C1N50_RS23600	COG4628	conserved protein (DUF2132)
C1N50_RS23605	COG0488	(ABC) transporter
C1N50_RS23620	COG0346	lactoylglutathione lyase activity
C1N50_RS23625	COG0384	phenazine biosynthesis protein PhzF
C1N50_RS23640	COG3220	belongs to the UPF0276 family
C1N50_RS23655	COG1271	oxidase subunit
C1N50_RS23660	COG1294	oxidase, subunit
C1N50_RS23700	COG2205	protein histidine kinase activity
C1N50_RS23705	COG0745	RESPONSE REGULATOR receiver
C1N50_RS23715	COG0454	-acetyltransferase
C1N50_RS23720	COG0148	phosphopyruvate hydratase activity
C1N50_RS23730	COG2814	Major facilitator Superfamily
C1N50_RS23740	COG2988	succinylglutamate desuccinylase activity
C1N50_RS23780	COG0628	permease
C1N50_RS23785	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C1N50_RS23800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1N50_RS23810	COG4628	conserved protein (DUF2132)
C1N50_RS23815	COG0583	DNA-binding transcription factor activity
C1N50_RS23825	COG1686	Belongs to the peptidase S11 family
C1N50_RS23850	COG0415	Belongs to the DNA photolyase family
C1N50_RS23855	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
C1N50_RS23865	COG4667	esterase of the alpha-beta hydrolase superfamily
C1N50_RS23870	COG2095	MarC family integral membrane protein
C1N50_RS23885	COG1596	polysaccharide export
C1N50_RS23890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N50_RS23925	COG1301	dicarboxylic acid transport
C1N50_RS23930	COG3339	Conserved Protein
C1N50_RS23935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N50_RS23940	COG0700	Nucleoside recognition
C1N50_RS23945	COG3366	ferrous iron transmembrane transporter activity
C1N50_RS23970	COG0366	Alpha amylase catalytic
C1N50_RS23980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1N50_RS23985	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C1N50_RS23990	COG1640	4-alpha-glucanotransferase
C1N50_RS23995	COG0058	SHG alpha-glucan phosphorylase activity
C1N50_RS24020	COG1999	signal sequence binding
C1N50_RS24030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N50_RS24030	COG1263	PTS System
C1N50_RS24035	COG1162	GTPase activity
C1N50_RS24040	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C1N50_RS24060	COG0531	amino acid
C1N50_RS24065	COG1982	Orn Lys Arg decarboxylase major
C1N50_RS24085	COG2356	endonuclease I
C1N50_RS24105	COG4580	involved in the transport of maltose and maltodextrins
C1N50_RS24115	COG2203	Gaf domain
C1N50_RS24115	COG2199	diguanylate cyclase activity
C1N50_RS24145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C1N50_RS24160	COG2814	Major facilitator Superfamily
C1N50_RS24175	COG0739	heme binding
C1N50_RS24190	COG0800	Aldolase
C1N50_RS24225	COG3121	Chaperone
C1N50_RS24230	COG3188	usher protein
C1N50_RS24260	COG0612	Peptidase, M16
C1N50_RS24265	COG0840	transmembrane signaling receptor activity
C1N50_RS24275	COG0826	peptidase U32
C1N50_RS24295	COG1335	isochorismatase
C1N50_RS24300	COG1136	(ABC) transporter
C1N50_RS24305	COG0577	efflux transmembrane transporter activity
C1N50_RS24350	COG1764	response to oxidative stress
C1N50_RS24355	COG1846	Transcriptional regulator
C1N50_RS24365	COG3634	alkyl hydroperoxide reductase activity
C1N50_RS24405	COG2610	gluconate transmembrane transporter activity
C1N50_RS24410	COG3622	Belongs to the hyi family
C1N50_RS24415	COG0235	Class ii aldolase
C1N50_RS24420	COG3395	kinase activity
C1N50_RS24425	COG2084	Dehydrogenase
C1N50_RS24430	COG1349	DNA-binding transcription factor activity
C1N50_RS24450	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C1N50_RS24460	COG1522	sequence-specific DNA binding
C1N50_RS24465	COG0544	peptidyl-prolyl cis-trans isomerase activity
C1N50_RS24470	COG0544	peptidyl-prolyl cis-trans isomerase activity
C1N50_RS24475	COG0544	peptidyl-prolyl cis-trans isomerase activity
C1N50_RS24480	COG2207	Transcriptional regulator
C1N50_RS24490	COG2258	MOSC domain
C1N50_RS24500	COG3713	MltA-interacting MipA family protein
C1N50_RS24505	COG0513	Belongs to the DEAD box helicase family
C1N50_RS24510	COG0667	Aldo Keto reductase
C1N50_RS24515	COG0583	DNA-binding transcription factor activity
C1N50_RS24520	COG1312	Catalyzes the dehydration of D-mannonate
C1N50_RS24525	COG2186	Transcriptional regulator
C1N50_RS24535	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1N50_RS24545	COG0246	Mannitol dehydrogenase
C1N50_RS24550	COG1904	glucuronate isomerase
C1N50_RS24555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N50_RS24560	COG0800	Aldolase
C1N50_RS24595	COG1132	(ABC) transporter
C1N50_RS24755	COG4166	transmembrane transport
C1N50_RS24770	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C1N50_RS24775	COG1263	PTS System
C1N50_RS24775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N50_RS24780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C1N50_RS24805	COG1444	tRNA N-acetyltransferase activity
C1N50_RS24830	COG4608	Belongs to the ABC transporter superfamily
C1N50_RS24835	COG0444	Belongs to the ABC transporter superfamily
C1N50_RS24845	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
C1N50_RS24845	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C1N50_RS24870	COG0772	Belongs to the SEDS family
C1N50_RS24890	COG1136	(ABC) transporter
C1N50_RS24910	COG3275	phosphorelay sensor kinase activity
C1N50_RS24915	COG3279	Response regulator of the LytR AlgR family
C1N50_RS24925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C1N50_RS24945	COG0786	glutamate:sodium symporter activity
C1N50_RS24950	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_RS24985	COG1131	(ABC) transporter
C1N50_RS24990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N50_RS24995	COG0786	glutamate:sodium symporter activity
C1N50_RS25030	COG2259	Doxx family
C1N50_RS25040	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C1N50_RS25045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C1N50_RS25055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C1N50_RS25105	COG5001	Diguanylate cyclase
C1N50_RS25115	COG1609	Transcriptional regulator
C1N50_RS25130	COG0395	ABC-type sugar transport system, permease component
C1N50_RS25135	COG2723	6-phospho-beta-galactosidase activity
C1N50_RS25140	COG3842	ATPase activity
C1N50_RS25145	COG1609	Transcriptional regulator
C1N50_RS25155	COG0747	negative chemotaxis
C1N50_RS25165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N50_RS25170	COG0444	Belongs to the ABC transporter superfamily
C1N50_RS25175	COG4608	Belongs to the ABC transporter superfamily
C1N50_RS25185	COG1609	Transcriptional regulator
C1N50_RS25205	COG1472	Belongs to the glycosyl hydrolase 3 family
C1N50_RS25210	COG0534	Mate efflux family protein
C1N50_RS25215	COG0564	pseudouridine synthase activity
C1N50_RS25220	COG0561	phosphatase activity
C1N50_RS25240	COG3152	Membrane
C1N50_RS25255	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C1N50_RS25270	COG0583	DNA-binding transcription factor activity
C1N50_RS25320	COG2076	Multidrug Resistance protein
C1N50_RS25335	COG1357	PFAM Pentapeptide repeats (8 copies)
C1N50_RS25340	COG3047	cAMP biosynthetic process
C1N50_RS25350	COG2814	Major facilitator Superfamily
C1N50_RS25455	COG3835	regulator
C1N50_RS25460	COG1929	Belongs to the glycerate kinase type-1 family
C1N50_RS25465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N50_RS25525	COG1028	Short-chain dehydrogenase reductase Sdr
C1N50_RS25535	COG3005	denitrification pathway
C1N50_RS25540	COG0243	molybdopterin cofactor binding
C1N50_RS25545	COG0671	phosphoesterase, PA-phosphatase related
C1N50_RS25560	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C1N50_RS25565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C1N50_RS25570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N50_RS25575	COG1116	anion transmembrane transporter activity
C1N50_RS25580	COG0351	phosphomethylpyrimidine kinase
C1N50_RS25585	COG0312	modulator of DNA gyrase
C1N50_RS25590	COG0312	modulator of DNA gyrase