locus-tag	class	description
C1N51_RS00030	COG0493	'glutamate synthase
C1N51_RS00040	COG0398	Pfam SNARE associated Golgi protein
C1N51_RS00045	COG4134	Bacterial extracellular solute-binding protein
C1N51_RS00050	COG4135	transport system, permease component
C1N51_RS00055	COG4136	ATPase activity
C1N51_RS00060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C1N51_RS00070	COG2814	Major facilitator Superfamily
C1N51_RS00075	COG3604	Transcriptional regulator
C1N51_RS00080	COG1151	hydroxylamine reductase activity
C1N51_RS00085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1N51_RS00095	COG0564	pseudouridine synthase activity
C1N51_RS00105	COG0733	neurotransmitter:sodium symporter activity
C1N51_RS00115	COG0626	cystathionine gamma-synthase activity
C1N51_RS00120	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C1N51_RS00140	COG2818	Glycosylase
C1N51_RS00160	COG1983	PspC domain protein
C1N51_RS00170	COG1842	Phage shock protein A
C1N51_RS00175	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C1N51_RS00185	COG4168	peptide transport system, permease
C1N51_RS00190	COG4171	peptide transport system, permease
C1N51_RS00200	COG4172	Belongs to the ABC transporter superfamily
C1N51_RS00210	COG1227	inorganic diphosphatase activity
C1N51_RS00225	COG0243	molybdopterin cofactor binding
C1N51_RS00230	COG3005	denitrification pathway
C1N51_RS00235	COG4459	periplasmic nitrate reductase
C1N51_RS00240	COG0390	transport system, permease component
C1N51_RS00245	COG2116	formate transmembrane transporter activity
C1N51_RS00270	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C1N51_RS00275	COG1435	thymidine kinase activity
C1N51_RS00280	COG0215	cysteine-tRNA ligase activity
C1N51_RS00285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C1N51_RS00290	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C1N51_RS00295	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C1N51_RS00300	COG3012	SEC-C Motif Domain Protein
C1N51_RS00305	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C1N51_RS00305	COG0140	phosphoribosyl-ATP diphosphatase activity
C1N51_RS00315	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C1N51_RS00320	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C1N51_RS00325	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C1N51_RS00325	COG0131	Imidazoleglycerol-phosphate dehydratase
C1N51_RS00335	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C1N51_RS00350	COG1757	Na H antiporter
C1N51_RS00360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N51_RS00370	COG0482	sulfurtransferase activity
C1N51_RS00380	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C1N51_RS00400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C1N51_RS00415	COG0300	oxidoreductase activity
C1N51_RS00440	COG2226	methyltransferase
C1N51_RS00460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C1N51_RS00480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C1N51_RS00490	COG1674	ftsk spoiiie
C1N51_RS00500	COG0686	Belongs to the AlaDH PNT family
C1N51_RS00510	COG0583	DNA-binding transcription factor activity
C1N51_RS00535	COG0402	S-adenosylhomocysteine deaminase activity
C1N51_RS00540	COG4934	collagen metabolic process
C1N51_RS00555	COG3568	Endonuclease Exonuclease Phosphatase
C1N51_RS00575	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C1N51_RS00590	COG1288	antiporter activity
C1N51_RS00600	COG2186	Transcriptional regulator
C1N51_RS00610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N51_RS00615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N51_RS00645	COG0747	negative chemotaxis
C1N51_RS00650	COG4608	Belongs to the ABC transporter superfamily
C1N51_RS00655	COG0444	Belongs to the ABC transporter superfamily
C1N51_RS00660	COG0534	Mate efflux family protein
C1N51_RS00670	COG2824	Alkylphosphonate utilization operon protein PhnA
C1N51_RS00675	COG2723	6-phospho-beta-galactosidase activity
C1N51_RS00680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N51_RS00680	COG1263	PTS System
C1N51_RS00700	COG3119	arylsulfatase activity
C1N51_RS00735	COG0457	Tetratricopeptide repeat
C1N51_RS00805	COG4790	Type iii secretion
C1N51_RS00810	COG4794	Type iii secretion
C1N51_RS00815	COG4791	protein targeting
C1N51_RS00820	COG4792	protein secretion
C1N51_RS00835	COG3177	Filamentation induced by cAMP protein fic
C1N51_RS00865	COG4669	(LipO)protein
C1N51_RS00960	COG2433	Pfam Transposase IS66
C1N51_RS00995	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C1N51_RS01015	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
C1N51_RS01020	COG1715	Restriction endonuclease
C1N51_RS01055	COG0784	Response regulator, receiver
C1N51_RS01055	COG2205	protein histidine kinase activity
C1N51_RS01065	COG0754	glutathionylspermidine amidase activity
C1N51_RS01075	COG3766	membrane
C1N51_RS01090	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C1N51_RS01095	COG2885	chlorophyll binding
C1N51_RS01100	COG0823	Involved in the tonB-independent uptake of proteins
C1N51_RS01115	COG0811	peptide transport
C1N51_RS01120	COG0824	Thioesterase
C1N51_RS01130	COG4890	Cyd operon protein YbgT
C1N51_RS01135	COG1294	oxidase, subunit
C1N51_RS01140	COG1271	oxidase subunit
C1N51_RS01150	COG0632	four-way junction helicase activity
C1N51_RS01155	COG0840	transmembrane signaling receptor activity
C1N51_RS01170	COG1801	Protein of unknown function DUF72
C1N51_RS01190	COG4067	protein conserved in archaea
C1N51_RS01190	COG0189	ligase activity
C1N51_RS01215	COG0318	PFAM AMP-dependent synthetase and ligase
C1N51_RS01230	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C1N51_RS01235	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C1N51_RS01245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1N51_RS01250	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C1N51_RS01255	COG0745	RESPONSE REGULATOR receiver
C1N51_RS01270	COG3070	regulator of competence-specific genes
C1N51_RS01290	COG0297	glycogen (starch) synthase activity
C1N51_RS01295	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1N51_RS01300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1N51_RS01330	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C1N51_RS01335	COG0542	response to heat
C1N51_RS01345	COG1278	Cold shock
C1N51_RS01355	COG1187	pseudouridine synthase activity
C1N51_RS01360	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C1N51_RS01370	COG1199	ATP-dependent helicase activity
C1N51_RS01375	COG0730	response to heat
C1N51_RS01380	COG3923	Primosomal replication protein n
C1N51_RS01390	COG0708	Exodeoxyribonuclease III
C1N51_RS01425	COG1882	Formate acetyltransferase
C1N51_RS01435	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1N51_RS01455	COG2766	serine protein kinase
C1N51_RS01460	COG2718	Belongs to the UPF0229 family
C1N51_RS01465	COG2719	SpoVR family
C1N51_RS01485	COG1132	(ABC) transporter
C1N51_RS01490	COG2333	competence protein COMEC
C1N51_RS01490	COG0658	competence protein
C1N51_RS01500	COG4591	ABC-type transport system involved in lipoprotein release permease component
C1N51_RS01505	COG1136	(ABC) transporter
C1N51_RS01510	COG4591	ABC-type transport system involved in lipoprotein release permease component
C1N51_RS01520	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C1N51_RS01535	COG1252	NADH dehydrogenase
C1N51_RS01565	COG0537	adenosine 5'-monophosphoramidase activity
C1N51_RS01585	COG2217	Heavy metal translocating P-type atpase
C1N51_RS01595	COG0517	IMP dehydrogenase activity
C1N51_RS01595	COG0516	GMP reductase activity
C1N51_RS01600	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
C1N51_RS01605	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C1N51_RS01610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1N51_RS01620	COG3706	GGDEF domain
C1N51_RS01635	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C1N51_RS01640	COG1946	Acyl-CoA thioesterase
C1N51_RS01645	COG1522	sequence-specific DNA binding
C1N51_RS01670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N51_RS01730	COG2855	membrane
C1N51_RS01740	COG0583	DNA-binding transcription factor activity
C1N51_RS01745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N51_RS01745	COG1263	PTS System
C1N51_RS01745	COG2190	(PTS) system
C1N51_RS01760	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C1N51_RS01765	COG0596	Alpha beta hydrolase
C1N51_RS01775	COG1169	isochorismate synthase
C1N51_RS01780	COG0436	Aminotransferase
C1N51_RS01785	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C1N51_RS01805	COG1555	photosystem II stabilization
C1N51_RS01810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1N51_RS01815	COG0776	regulation of translation
C1N51_RS01820	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C1N51_RS01855	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1N51_RS01860	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1N51_RS01865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1N51_RS01885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N51_RS01890	COG0569	domain protein
C1N51_RS01895	COG0513	Belongs to the DEAD box helicase family
C1N51_RS01900	COG1253	flavin adenine dinucleotide binding
C1N51_RS01905	COG4771	TonB-dependent receptor
C1N51_RS01920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1N51_RS01920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1N51_RS01925	COG3433	isochorismatase activity
C1N51_RS01925	COG1535	isochorismatase
C1N51_RS01930	COG1021	2,3-dihydroxybenzoate-AMP ligase
C1N51_RS01935	COG1169	isochorismate synthase
C1N51_RS01945	COG1028	Short-chain dehydrogenase reductase Sdr
C1N51_RS01960	COG2226	methyltransferase
C1N51_RS01970	COG3550	peptidyl-serine autophosphorylation
C1N51_RS01975	COG1396	sequence-specific DNA binding
C1N51_RS02035	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C1N51_RS02080	COG2852	Protein conserved in bacteria
C1N51_RS02085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1N51_RS02095	COG2951	lytic endotransglycosylase activity
C1N51_RS02110	COG2894	cell division
C1N51_RS02115	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C1N51_RS02120	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C1N51_RS02125	COG0318	PFAM AMP-dependent synthetase and ligase
C1N51_RS02130	COG2267	carboxylic ester hydrolase activity
C1N51_RS02135	COG3065	identical protein binding
C1N51_RS02145	COG1214	PFAM Peptidase M22, glycoprotease
C1N51_RS02150	COG1199	ATP-dependent helicase activity
C1N51_RS02160	COG0788	formyltetrahydrofolate deformylase activity
C1N51_RS02175	COG3102	Protein conserved in bacteria
C1N51_RS02210	COG1918	ferrous iron import across plasma membrane
C1N51_RS02215	COG4977	sequence-specific DNA binding
C1N51_RS02220	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C1N51_RS02225	COG1121	(ABC) transporter
C1N51_RS02230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1N51_RS02245	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N51_RS02250	COG0567	Dehydrogenase, E1 component
C1N51_RS02260	COG1053	succinate dehydrogenase
C1N51_RS02265	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C1N51_RS02280	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C1N51_RS02305	COG2433	Pfam Transposase IS66
C1N51_RS02310	COG0033	Phosphoglucomutase
C1N51_RS02315	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C1N51_RS02320	COG0596	Alpha beta hydrolase
C1N51_RS02340	COG0735	belongs to the Fur family
C1N51_RS02345	COG2165	general secretion pathway protein
C1N51_RS02355	COG1263	PTS System
C1N51_RS02355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N51_RS02355	COG2190	(PTS) system
C1N51_RS02365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C1N51_RS02370	COG1940	carbohydrate kinase activity
C1N51_RS02370	COG1846	Transcriptional regulator
C1N51_RS02375	COG4651	solute:proton antiporter activity
C1N51_RS02375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C1N51_RS02380	COG0367	asparagine synthase
C1N51_RS02390	COG3104	oligopeptide transport
C1N51_RS02395	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C1N51_RS02410	COG3710	Transcriptional regulator
C1N51_RS02430	COG0622	Phosphoesterase
C1N51_RS02460	COG1090	epimerase
C1N51_RS02465	COG0300	oxidoreductase activity
C1N51_RS02475	COG3118	belongs to the thioredoxin family
C1N51_RS02480	COG3118	belongs to the thioredoxin family
C1N51_RS02480	COG0457	Tetratricopeptide repeat
C1N51_RS02485	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C1N51_RS02490	COG1215	transferase activity, transferring glycosyl groups
C1N51_RS02495	COG1215	transferase activity, transferring glycosyl groups
C1N51_RS02500	COG1192	Involved in chromosome partitioning
C1N51_RS02515	COG2194	sulfuric ester hydrolase activity
C1N51_RS02520	COG0330	HflC and HflK could
C1N51_RS02555	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
C1N51_RS02560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C1N51_RS02570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N51_RS02575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1N51_RS02580	COG2190	(PTS) system
C1N51_RS02585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N51_RS02590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N51_RS02600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N51_RS02615	COG3951	Flagellar rod assembly protein muramidase FlgJ
C1N51_RS02615	COG1705	Flagellar rod assembly protein muramidase FlgJ
C1N51_RS02620	COG1706	bacterial-type flagellum-dependent cell motility
C1N51_RS02625	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C1N51_RS02635	COG4787	bacterial-type flagellum-dependent cell motility
C1N51_RS02640	COG1749	Flagellar hook protein flgE
C1N51_RS02650	COG1558	bacterial-type flagellum-dependent cell motility
C1N51_RS02655	COG1815	bacterial-type flagellum-dependent cell motility
C1N51_RS02660	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C1N51_RS02665	COG0835	chemotaxis
C1N51_RS02665	COG0784	Response regulator, receiver
C1N51_RS02730	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C1N51_RS02745	COG2217	Heavy metal translocating P-type atpase
C1N51_RS02745	COG2608	mercury ion transmembrane transporter activity
C1N51_RS02785	COG2840	Smr protein MutS2
C1N51_RS02790	COG1187	pseudouridine synthase activity
C1N51_RS02795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C1N51_RS02800	COG0737	Belongs to the 5'-nucleotidase family
C1N51_RS02810	COG2912	Transglutaminase-like superfamily
C1N51_RS02815	COG3094	Invasion gene expression up-regulator, SirB
C1N51_RS02820	COG2890	protein-(glutamine-N5) methyltransferase activity
C1N51_RS02845	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C1N51_RS02970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1N51_RS02985	COG1702	phosphate starvation-inducible protein PhoH
C1N51_RS02995	COG4535	Mg2 and Co2 transporter CorC
C1N51_RS03000	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C1N51_RS03005	COG2888	peptidyl-tyrosine sulfation
C1N51_RS03015	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
C1N51_RS03020	COG1466	dna polymerase III delta subunit
C1N51_RS03025	COG0799	negative regulation of ribosome biogenesis
C1N51_RS03035	COG0768	penicillin binding
C1N51_RS03040	COG0772	Belongs to the SEDS family
C1N51_RS03045	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C1N51_RS03050	COG1686	Belongs to the peptidase S11 family
C1N51_RS03070	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C1N51_RS03075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C1N51_RS03080	COG0366	Alpha amylase catalytic
C1N51_RS03085	COG1263	PTS System
C1N51_RS03085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N51_RS03095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C1N51_RS03100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C1N51_RS03105	COG2011	ABC-type metal ion transport system permease component
C1N51_RS03110	COG1464	Belongs to the NlpA lipoprotein family
C1N51_RS03120	COG0737	Belongs to the 5'-nucleotidase family
C1N51_RS03125	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
C1N51_RS03150	COG1611	Belongs to the LOG family
C1N51_RS03165	COG2363	Small membrane protein
C1N51_RS03175	COG0583	DNA-binding transcription factor activity
C1N51_RS03190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C1N51_RS03200	COG0142	geranyltranstransferase activity
C1N51_RS03210	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C1N51_RS03215	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C1N51_RS03240	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1N51_RS03240	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1N51_RS03245	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C1N51_RS03250	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C1N51_RS03265	COG1073	alpha beta
C1N51_RS03275	COG2252	PERMEase
C1N51_RS03280	COG2195	Cleaves the N-terminal amino acid of tripeptides
C1N51_RS03305	COG0047	phosphoribosylformylglycinamidine synthase activity
C1N51_RS03305	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C1N51_RS03320	COG0590	tRNA wobble adenosine to inosine editing
C1N51_RS03330	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C1N51_RS03350	COG4969	Belongs to the N-Me-Phe pilin family
C1N51_RS03370	COG1301	dicarboxylic acid transport
C1N51_RS03385	COG0497	DNA recombination
C1N51_RS03395	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1N51_RS03400	COG2914	Belongs to the UPF0125 (RnfH) family
C1N51_RS03405	COG2867	negative regulation of translational initiation
C1N51_RS03430	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C1N51_RS03465	COG0583	DNA-binding transcription factor activity
C1N51_RS03470	COG1289	transmembrane transporter activity
C1N51_RS03490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1N51_RS03495	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C1N51_RS03515	COG0583	DNA-binding transcription factor activity
C1N51_RS03525	COG1115	amino acid carrier protein
C1N51_RS03530	COG1584	GPR1 FUN34 yaaH family protein
C1N51_RS03540	COG1757	Na H antiporter
C1N51_RS03550	COG0517	IMP dehydrogenase activity
C1N51_RS03550	COG0516	GMP reductase activity
C1N51_RS03565	COG2203	Gaf domain
C1N51_RS03565	COG2199	diguanylate cyclase activity
C1N51_RS03580	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1N51_RS03585	COG2976	Protein conserved in bacteria
C1N51_RS03620	COG2975	iron-sulfur cluster assembly
C1N51_RS03625	COG0633	Ferredoxin
C1N51_RS03640	COG0316	Belongs to the HesB IscA family
C1N51_RS03645	COG0822	iron-sulfur transferase activity
C1N51_RS03660	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C1N51_RS03665	COG0483	inositol monophosphate 1-phosphatase activity
C1N51_RS03675	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N51_RS03680	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N51_RS03685	COG1862	Preprotein translocase
C1N51_RS03710	COG0517	IMP dehydrogenase activity
C1N51_RS03720	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C1N51_RS03725	COG0583	DNA-binding transcription factor activity
C1N51_RS03730	COG0450	alkyl hydroperoxide reductase
C1N51_RS03760	COG0704	Plays a role in the regulation of phosphate uptake
C1N51_RS03765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C1N51_RS03770	COG0581	inorganic phosphate transmembrane transporter activity
C1N51_RS03775	COG0573	inorganic phosphate transmembrane transporter activity
C1N51_RS03780	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C1N51_RS03785	COG0248	Ppx GppA phosphatase
C1N51_RS03795	COG5002	protein histidine kinase activity
C1N51_RS03800	COG0745	RESPONSE REGULATOR receiver
C1N51_RS03810	COG0826	peptidase U32
C1N51_RS03815	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1N51_RS03880	COG0542	response to heat
C1N51_RS03885	COG1496	oxidoreductase activity
C1N51_RS03890	COG0564	pseudouridine synthase activity
C1N51_RS03895	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1N51_RS03900	COG0741	lytic transglycosylase activity
C1N51_RS03905	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C1N51_RS03910	COG1605	Chorismate mutase
C1N51_RS03910	COG0077	Prephenate dehydratase
C1N51_RS03915	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
C1N51_RS03930	COG0488	(ABC) transporter
C1N51_RS03940	COG0739	heme binding
C1N51_RS03945	COG0287	Prephenate dehydrogenase
C1N51_RS03945	COG1605	Chorismate mutase
C1N51_RS03950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1N51_RS03960	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C1N51_RS03980	COG1966	Carbon starvation protein
C1N51_RS03985	COG3275	phosphorelay sensor kinase activity
C1N51_RS03990	COG3279	Response regulator of the LytR AlgR family
C1N51_RS04005	COG2433	Pfam Transposase IS66
C1N51_RS04010	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C1N51_RS04015	COG1047	Peptidyl-prolyl cis-trans
C1N51_RS04030	COG0196	riboflavin kinase activity
C1N51_RS04035	COG0728	peptidoglycan biosynthetic process
C1N51_RS04040	COG0268	Binds directly to 16S ribosomal RNA
C1N51_RS04045	COG0640	Transcriptional regulator
C1N51_RS04050	COG0583	DNA-binding transcription factor activity
C1N51_RS04055	COG1283	sodium-dependent phosphate transmembrane transporter activity
C1N51_RS04075	COG0730	response to heat
C1N51_RS04100	COG0667	Aldo Keto reductase
C1N51_RS04125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C1N51_RS04130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1N51_RS04135	COG4974	Belongs to the 'phage' integrase family
C1N51_RS04140	COG0716	FMN binding
C1N51_RS04155	COG0513	Belongs to the DEAD box helicase family
C1N51_RS04165	COG3022	response to hydroperoxide
C1N51_RS04170	COG1115	amino acid carrier protein
C1N51_RS04205	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C1N51_RS04210	COG0083	homoserine kinase activity
C1N51_RS04225	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C1N51_RS04240	COG0745	RESPONSE REGULATOR receiver
C1N51_RS04250	COG0784	Response regulator, receiver
C1N51_RS04250	COG2198	Histidine kinase
C1N51_RS04250	COG5002	protein histidine kinase activity
C1N51_RS04260	COG2203	Gaf domain
C1N51_RS04260	COG4251	negative regulation of phosphorylation
C1N51_RS04260	COG5001	Diguanylate cyclase
C1N51_RS04260	COG3706	GGDEF domain
C1N51_RS04265	COG1242	4 iron, 4 sulfur cluster binding
C1N51_RS04270	COG0067	glutamate synthase
C1N51_RS04270	COG0069	glutamate synthase activity
C1N51_RS04270	COG0070	glutamate synthase
C1N51_RS04280	COG0069	glutamate synthase activity
C1N51_RS04280	COG0067	glutamate synthase
C1N51_RS04280	COG0070	glutamate synthase
C1N51_RS04285	COG0493	'glutamate synthase
C1N51_RS04310	COG2860	membrane
C1N51_RS04315	COG0583	DNA-binding transcription factor activity
C1N51_RS04320	COG0730	response to heat
C1N51_RS04340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C1N51_RS04345	COG0505	Belongs to the CarA family
C1N51_RS04355	COG0494	nUDIX hydrolase
C1N51_RS04375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C1N51_RS04380	COG0849	cell division
C1N51_RS04385	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C1N51_RS04400	COG0772	Belongs to the SEDS family
C1N51_RS04415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C1N51_RS04420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C1N51_RS04425	COG0768	penicillin binding
C1N51_RS04430	COG3116	cell division
C1N51_RS04455	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C1N51_RS04470	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C1N51_RS04475	COG2823	Periplasmic or secreted lipoprotein
C1N51_RS04480	COG2969	positive regulation of protein catabolic process
C1N51_RS04485	COG0625	glutathione transferase activity
C1N51_RS04490	COG2857	Cytochrome c1
C1N51_RS04495	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C1N51_RS04500	COG0723	plastoquinol--plastocyanin reductase activity
C1N51_RS04520	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C1N51_RS04530	COG3105	Protein conserved in bacteria
C1N51_RS04535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1N51_RS04540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1N51_RS04555	COG2433	Pfam Transposase IS66
C1N51_RS04560	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C1N51_RS04570	COG3150	esterase
C1N51_RS04580	COG3151	Protein conserved in bacteria
C1N51_RS04585	COG0494	nUDIX hydrolase
C1N51_RS04590	COG1538	Outer membrane efflux protein
C1N51_RS04600	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C1N51_RS04610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C1N51_RS04615	COG3025	triphosphatase activity
C1N51_RS04620	COG1392	Phosphate transport regulator
C1N51_RS04625	COG0306	phosphate transporter
C1N51_RS04630	COG4991	sh3 domain protein
C1N51_RS04655	COG2433	Pfam Transposase IS66
C1N51_RS04670	COG3267	Type II secretory pathway component ExeA
C1N51_RS04670	COG3409	Peptidoglycan-binding domain 1 protein
C1N51_RS04685	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C1N51_RS04690	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C1N51_RS04700	COG0596	Alpha beta hydrolase
C1N51_RS04705	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C1N51_RS04710	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C1N51_RS04715	COG1610	YqeY-like protein
C1N51_RS04720	COG0358	DNA primase activity
C1N51_RS04760	COG2213	PTS system mannitol-specific
C1N51_RS04760	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N51_RS04770	COG3722	fumarate hydratase activity
C1N51_RS04775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1N51_RS04780	COG5002	protein histidine kinase activity
C1N51_RS04800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C1N51_RS04805	COG1349	DNA-binding transcription factor activity
C1N51_RS04810	COG0469	pyruvate kinase activity
C1N51_RS04820	COG3706	GGDEF domain
C1N51_RS04825	COG0440	acetolactate synthase activity
C1N51_RS04830	COG0028	Belongs to the TPP enzyme family
C1N51_RS04835	COG1022	Amp-dependent synthetase and ligase
C1N51_RS04840	COG0583	DNA-binding transcription factor activity
C1N51_RS04870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C1N51_RS04875	COG0473	3-isopropylmalate dehydrogenase activity
C1N51_RS04895	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C1N51_RS04900	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C1N51_RS04905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1N51_RS04910	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C1N51_RS04935	COG3610	response to peptide
C1N51_RS04940	COG2966	Psort location CytoplasmicMembrane, score
C1N51_RS04955	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C1N51_RS04960	COG0142	geranyltranstransferase activity
C1N51_RS04980	COG2358	TRAP transporter, solute receptor (TAXI family
C1N51_RS04995	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C1N51_RS05000	COG1178	ABC-type Fe3 transport system permease component
C1N51_RS05005	COG4143	(ABC) transporter
C1N51_RS05010	COG0163	prenyltransferase activity
C1N51_RS05015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C1N51_RS05025	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C1N51_RS05040	COG2105	PFAM AIG2 family protein
C1N51_RS05050	COG0729	surface antigen
C1N51_RS05055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N51_RS05065	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C1N51_RS05080	COG1136	(ABC) transporter
C1N51_RS05100	COG0529	Catalyzes the synthesis of activated sulfate
C1N51_RS05105	COG0471	metal ion transport
C1N51_RS05105	COG3273	potassium ion transport
C1N51_RS05120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C1N51_RS05120	COG1648	precorrin-2 dehydrogenase activity
C1N51_RS05125	COG0737	Belongs to the 5'-nucleotidase family
C1N51_RS05135	COG0513	Belongs to the DEAD box helicase family
C1N51_RS05140	COG2153	protein acetylation
C1N51_RS05155	COG0545	Peptidyl-prolyl cis-trans isomerase
C1N51_RS05165	COG0203	ribosomal protein L17
C1N51_RS05170	COG0202	RNA polymerase activity
C1N51_RS05180	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C1N51_RS05185	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C1N51_RS05190	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C1N51_RS05195	COG0201	protein transport
C1N51_RS05205	COG1841	ribosomal large subunit assembly
C1N51_RS05290	COG0088	Forms part of the polypeptide exit tunnel
C1N51_RS05310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C1N51_RS05315	COG1609	Transcriptional regulator
C1N51_RS05340	COG1575	Belongs to the MenA family. Type 1 subfamily
C1N51_RS05345	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C1N51_RS05355	COG1494	fructose-1,6-bisphosphatase
C1N51_RS05385	COG0149	triose-phosphate isomerase activity
C1N51_RS05400	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C1N51_RS05425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C1N51_RS05435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C1N51_RS05440	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C1N51_RS05445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C1N51_RS05450	COG1215	transferase activity, transferring glycosyl groups
C1N51_RS05465	COG0438	transferase activity, transferring glycosyl groups
C1N51_RS05505	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C1N51_RS05545	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1N51_RS05555	COG1560	Kdo2-lipid A biosynthetic process
C1N51_RS05565	COG0438	transferase activity, transferring glycosyl groups
C1N51_RS05570	COG1519	Transferase
C1N51_RS05575	COG1216	Glycosyl transferase, family 2
C1N51_RS05575	COG1442	glycosyl transferase family 8
C1N51_RS05585	COG5039	Polysaccharide pyruvyl transferase
C1N51_RS05590	COG3642	lipopolysaccharide core region biosynthetic process
C1N51_RS05595	COG0859	PFAM glycosyl transferase family 9
C1N51_RS05600	COG0463	Glycosyl transferase, family 2
C1N51_RS05605	COG0438	transferase activity, transferring glycosyl groups
C1N51_RS05620	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C1N51_RS05650	COG0840	transmembrane signaling receptor activity
C1N51_RS05660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C1N51_RS05670	COG1560	Kdo2-lipid A biosynthetic process
C1N51_RS05675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C1N51_RS05680	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C1N51_RS05685	COG1561	YicC-like family, N-terminal region
C1N51_RS05705	COG4608	Belongs to the ABC transporter superfamily
C1N51_RS05710	COG0444	Belongs to the ABC transporter superfamily
C1N51_RS05715	COG0747	negative chemotaxis
C1N51_RS05720	COG4239	(ABC) transporter, permease
C1N51_RS05725	COG4174	ABC transporter (Permease)
C1N51_RS05745	COG0811	peptide transport
C1N51_RS05750	COG0848	biopolymer transport protein
C1N51_RS05765	COG0194	GDP metabolic process
C1N51_RS05770	COG1758	RNA polymerase activity
C1N51_RS05775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C1N51_RS05780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1N51_RS05790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C1N51_RS05800	COG2233	PERMEase
C1N51_RS05850	COG1061	Type III restriction enzyme res subunit
C1N51_RS05865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1N51_RS05900	COG2183	response to ionizing radiation
C1N51_RS05915	COG1040	competence protein
C1N51_RS05925	COG0494	nUDIX hydrolase
C1N51_RS05930	COG1218	3'(2'),5'-bisphosphate nucleotidase
C1N51_RS05940	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C1N51_RS05945	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C1N51_RS05950	COG3156	type II secretion system protein K
C1N51_RS05955	COG4795	General secretion pathway protein
C1N51_RS05960	COG2165	general secretion pathway protein
C1N51_RS05965	COG2165	general secretion pathway protein
C1N51_RS05970	COG2165	general secretion pathway protein
C1N51_RS05975	COG1459	type II secretion system
C1N51_RS05980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1N51_RS05990	COG3031	protein transport across the cell outer membrane
C1N51_RS05995	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C1N51_RS06015	COG0456	acetyltransferase
C1N51_RS06020	COG1490	D-aminoacyl-tRNA deacylase activity
C1N51_RS06040	COG1217	gtp-binding protein TYPA
C1N51_RS06050	COG0174	glutamine synthetase
C1N51_RS06060	COG3852	Histidine kinase
C1N51_RS06065	COG2204	response regulator
C1N51_RS06070	COG5001	Diguanylate cyclase
C1N51_RS06070	COG3300	MHYT domain
C1N51_RS06075	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C1N51_RS06110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C1N51_RS06120	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1N51_RS06120	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1N51_RS06140	COG0084	hydrolase, TatD family'
C1N51_RS06145	COG0805	protein transport
C1N51_RS06150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C1N51_RS06165	COG3165	ubiquinone biosynthetic process from chorismate
C1N51_RS06175	COG1322	Protein conserved in bacteria
C1N51_RS06190	COG1910	domain protein
C1N51_RS06215	COG2081	HI0933 family
C1N51_RS06225	COG1528	Iron-storage protein
C1N51_RS06230	COG0589	response to stress
C1N51_RS06250	COG5002	protein histidine kinase activity
C1N51_RS06250	COG5001	Diguanylate cyclase
C1N51_RS06255	COG1522	sequence-specific DNA binding
C1N51_RS06270	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C1N51_RS06280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1N51_RS06285	COG0800	Aldolase
C1N51_RS06290	COG2610	gluconate transmembrane transporter activity
C1N51_RS06295	COG3265	gluconokinase activity
C1N51_RS06300	COG0129	dihydroxy-acid dehydratase activity
C1N51_RS06315	COG2076	Multidrug Resistance protein
C1N51_RS06320	COG0583	DNA-binding transcription factor activity
C1N51_RS06325	COG1609	Transcriptional regulator
C1N51_RS06330	COG0515	serine threonine protein kinase
C1N51_RS06360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N51_RS06365	COG0601	transmembrane transport
C1N51_RS06370	COG4166	transmembrane transport
C1N51_RS06375	COG4172	Belongs to the ABC transporter superfamily
C1N51_RS06425	COG1309	transcriptional regulator
C1N51_RS06430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N51_RS06435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N51_RS06445	COG2960	long-chain fatty acid transporting porin activity
C1N51_RS06455	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C1N51_RS06460	COG0583	DNA-binding transcription factor activity
C1N51_RS06505	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C1N51_RS06530	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C1N51_RS06535	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C1N51_RS06540	COG0551	DNA topoisomerase type I activity
C1N51_RS06550	COG0758	DNA mediated transformation
C1N51_RS06560	COG0242	peptide deformylase activity
C1N51_RS06570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C1N51_RS06570	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C1N51_RS06575	COG0569	domain protein
C1N51_RS06580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N51_RS06590	COG1272	protein, Hemolysin III
C1N51_RS06595	COG4326	sporulation control protein
C1N51_RS06605	COG3084	Protein conserved in bacteria
C1N51_RS06615	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C1N51_RS06620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1N51_RS06625	COG0204	Acyl-transferase
C1N51_RS06635	COG2199	diguanylate cyclase activity
C1N51_RS06640	COG0606	chelatase, subunit chli
C1N51_RS06680	COG3335	DDE superfamily endonuclease
C1N51_RS06705	COG3978	acetolactate synthase activity
C1N51_RS06710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C1N51_RS06715	COG0129	dihydroxy-acid dehydratase activity
C1N51_RS06725	COG3706	GGDEF domain
C1N51_RS06730	COG0583	DNA-binding transcription factor activity
C1N51_RS06735	COG2814	Major facilitator Superfamily
C1N51_RS06740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N51_RS06745	COG0765	amino acid transport
C1N51_RS06755	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C1N51_RS06765	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C1N51_RS06795	COG3312	ion transport
C1N51_RS06800	COG1475	DNA binding
C1N51_RS06805	COG1192	Involved in chromosome partitioning
C1N51_RS06820	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C1N51_RS06835	COG1395	domain, Protein
C1N51_RS06870	COG3645	SOS response
C1N51_RS06880	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C1N51_RS06915	COG4974	Belongs to the 'phage' integrase family
C1N51_RS06945	COG1126	abc transporter atp-binding protein
C1N51_RS06970	COG0592	DNA-directed DNA polymerase activity
C1N51_RS06980	COG0187	DNA topoisomerase II activity
C1N51_RS06985	COG0071	Belongs to the small heat shock protein (HSP20) family
C1N51_RS06990	COG3977	Valine--pyruvate aminotransferase
C1N51_RS07005	COG2119	membrane
C1N51_RS07015	COG0425	Belongs to the sulfur carrier protein TusA family
C1N51_RS07030	COG0604	alcohol dehydrogenase
C1N51_RS07035	COG0183	Belongs to the thiolase family
C1N51_RS07045	COG1739	Uncharacterized protein family UPF0029
C1N51_RS07050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N51_RS07100	COG2132	Multicopper oxidase
C1N51_RS07120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C1N51_RS07125	COG2104	thiamine diphosphate biosynthetic process
C1N51_RS07140	COG0006	proline dipeptidase activity
C1N51_RS07140	COG0006	proline dipeptidase activity
C1N51_RS07150	COG2814	Major facilitator Superfamily
C1N51_RS07170	COG3220	belongs to the UPF0276 family
C1N51_RS07180	COG0210	DNA helicase
C1N51_RS07190	COG0405	Gamma-glutamyltransferase
C1N51_RS07195	COG1280	lysine exporter protein (LysE YggA)
C1N51_RS07215	COG2962	Rard protein
C1N51_RS07220	COG0514	ATP-dependent DNA helicase (RecQ)
C1N51_RS07235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C1N51_RS07250	COG3118	belongs to the thioredoxin family
C1N51_RS07265	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C1N51_RS07270	COG0633	Ferredoxin
C1N51_RS07315	COG3071	HemY protein
C1N51_RS07320	COG2959	enzyme of heme biosynthesis
C1N51_RS07325	COG1587	Uroporphyrinogen-III synthase
C1N51_RS07335	COG3072	Adenylate cyclase
C1N51_RS07350	COG0019	diaminopimelate decarboxylase activity
C1N51_RS07370	COG1011	Hydrolase
C1N51_RS07375	COG2199	diguanylate cyclase activity
C1N51_RS07375	COG2200	EAL domain
C1N51_RS07375	COG3287	FIST C domain
C1N51_RS07380	COG3148	PFAM DTW domain containing protein
C1N51_RS07395	COG0561	phosphatase activity
C1N51_RS07400	COG2267	carboxylic ester hydrolase activity
C1N51_RS07405	COG1280	lysine exporter protein (LysE YggA)
C1N51_RS07410	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C1N51_RS07415	COG0640	Transcriptional regulator
C1N51_RS07420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C1N51_RS07475	COG2095	MarC family integral membrane protein
C1N51_RS07485	COG0742	ribosomal rna small subunit methyltransferase
C1N51_RS07490	COG0552	protein localization to endoplasmic reticulum
C1N51_RS07495	COG2884	Cell division ATP-binding protein ftsE
C1N51_RS07500	COG2177	Part of the ABC transporter FtsEX involved in
C1N51_RS07520	COG0705	Rhomboid family
C1N51_RS07525	COG1580	Controls the rotational direction of flagella during chemotaxis
C1N51_RS07530	COG3161	chorismate lyase activity
C1N51_RS07540	COG2937	Belongs to the GPAT DAPAT family
C1N51_RS07560	COG0534	Mate efflux family protein
C1N51_RS07565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1N51_RS07665	COG2433	Pfam Transposase IS66
C1N51_RS07680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1N51_RS07690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C1N51_RS07740	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C1N51_RS07745	COG0250	Participates in transcription elongation, termination and antitermination
C1N51_RS07760	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C1N51_RS07785	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
C1N51_RS07790	COG2816	NAD+ diphosphatase activity
C1N51_RS07810	COG1573	uracil-dna glycosylase
C1N51_RS07820	COG3068	Protein conserved in bacteria
C1N51_RS07825	COG1253	flavin adenine dinucleotide binding
C1N51_RS07840	COG0151	Belongs to the GarS family
C1N51_RS07850	COG0789	Transcriptional regulator
C1N51_RS07855	COG3710	Transcriptional regulator
C1N51_RS07865	COG0531	amino acid
C1N51_RS07870	COG1982	Orn Lys Arg decarboxylase major
C1N51_RS07915	COG2199	diguanylate cyclase activity
C1N51_RS07920	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C1N51_RS07925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1N51_RS07940	COG0439	Biotin carboxylase
C1N51_RS07945	COG0511	ligase activity, forming carbon-carbon bonds
C1N51_RS07950	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C1N51_RS07955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1N51_RS07970	COG2814	Major facilitator Superfamily
C1N51_RS07975	COG2205	protein histidine kinase activity
C1N51_RS07975	COG0784	Response regulator, receiver
C1N51_RS07975	COG2198	Histidine kinase
C1N51_RS07995	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C1N51_RS08005	COG2095	MarC family integral membrane protein
C1N51_RS08015	COG4232	protein-disulfide reductase activity
C1N51_RS08020	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C1N51_RS08025	COG1027	Aspartate ammonia-lyase
C1N51_RS08030	COG3030	protein affecting phage T7 exclusion by the F plasmid
C1N51_RS08035	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C1N51_RS08045	COG2205	protein histidine kinase activity
C1N51_RS08050	COG0745	RESPONSE REGULATOR receiver
C1N51_RS08070	COG0534	Mate efflux family protein
C1N51_RS08090	COG1136	(ABC) transporter
C1N51_RS08105	COG1509	lysine 2,3-aminomutase activity
C1N51_RS08135	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C1N51_RS08140	COG1053	succinate dehydrogenase
C1N51_RS08165	COG4942	peptidase
C1N51_RS08170	COG1045	serine acetyltransferase
C1N51_RS08185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N51_RS08190	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C1N51_RS08205	COG0471	metal ion transport
C1N51_RS08215	COG1162	GTPase activity
C1N51_RS08290	COG2433	Pfam Transposase IS66
C1N51_RS08295	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C1N51_RS08300	COG0802	atpase or kinase
C1N51_RS08305	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1N51_RS08310	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C1N51_RS08325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C1N51_RS08330	COG0330	HflC and HflK could
C1N51_RS08335	COG0330	HflC and HflK could
C1N51_RS08340	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C1N51_RS08345	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C1N51_RS08355	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C1N51_RS08360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1N51_RS08360	COG1017	nitric oxide dioxygenase activity
C1N51_RS08370	COG0557	exoribonuclease II activity
C1N51_RS08375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1N51_RS08380	COG0546	phosphoglycolate phosphatase activity
C1N51_RS08400	COG0512	Glutamine amidotransferase of anthranilate synthase
C1N51_RS08405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C1N51_RS08425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1N51_RS08430	COG3954	Phosphoribulokinase
C1N51_RS08440	COG0429	hydrolase of the alpha beta-hydrolase fold
C1N51_RS08450	COG0488	(ABC) transporter
C1N51_RS08460	COG2249	NAD(P)H dehydrogenase (quinone) activity
C1N51_RS08475	COG1047	Peptidyl-prolyl cis-trans
C1N51_RS08485	COG1446	asparaginase
C1N51_RS08500	COG0545	Peptidyl-prolyl cis-trans isomerase
C1N51_RS08505	COG2964	Protein conserved in bacteria
C1N51_RS08510	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C1N51_RS08515	COG2923	Belongs to the DsrF TusC family
C1N51_RS08520	COG2168	tRNA wobble position uridine thiolation
C1N51_RS08535	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C1N51_RS08545	COG2906	2 iron, 2 sulfur cluster binding
C1N51_RS08555	COG0281	malic enzyme
C1N51_RS08565	COG0626	cystathionine gamma-synthase activity
C1N51_RS08570	COG0460	homoserine dehydrogenase
C1N51_RS08570	COG0527	aspartate kinase activity
C1N51_RS08575	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C1N51_RS08585	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C1N51_RS08595	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C1N51_RS08610	COG0165	Argininosuccinate lyase
C1N51_RS08610	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C1N51_RS08625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1N51_RS08630	COG0678	peroxiredoxin activity
C1N51_RS08630	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C1N51_RS08640	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C1N51_RS08685	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C1N51_RS08690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C1N51_RS08700	COG2965	DNA replication, synthesis of RNA primer
C1N51_RS08720	COG0305	Participates in initiation and elongation during chromosome replication
C1N51_RS08725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C1N51_RS08735	COG0432	Pfam Uncharacterised protein family UPF0047
C1N51_RS08750	COG0735	belongs to the Fur family
C1N51_RS08755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1N51_RS08775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C1N51_RS08880	COG2433	Pfam Transposase IS66
C1N51_RS08900	COG1410	methionine synthase
C1N51_RS08900	COG0646	methionine synthase
C1N51_RS08905	COG0527	aspartate kinase activity
C1N51_RS08935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C1N51_RS08950	COG0629	single-stranded DNA binding
C1N51_RS08980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C1N51_RS09065	COG2199	diguanylate cyclase activity
C1N51_RS09065	COG2200	EAL domain
C1N51_RS09090	COG3267	Type II secretory pathway component ExeA
C1N51_RS09090	COG3409	Peptidoglycan-binding domain 1 protein
C1N51_RS09100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1N51_RS09105	COG1459	type II secretion system
C1N51_RS09115	COG2165	general secretion pathway protein
C1N51_RS09130	COG2165	general secretion pathway protein
C1N51_RS09150	COG1077	Cell shape determining protein MreB Mrl
C1N51_RS09155	COG1792	Involved in formation and maintenance of cell shape
C1N51_RS09160	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C1N51_RS09165	COG0424	maF-like protein
C1N51_RS09175	COG3164	Protein of unknown function
C1N51_RS09180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1N51_RS09185	COG0312	modulator of DNA gyrase
C1N51_RS09190	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C1N51_RS09205	COG0564	pseudouridine synthase activity
C1N51_RS09225	COG0312	modulator of DNA gyrase
C1N51_RS09230	COG2239	Acts as a magnesium transporter
C1N51_RS09235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N51_RS09245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N51_RS09250	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C1N51_RS09260	COG1137	ATPase activity
C1N51_RS09265	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C1N51_RS09275	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C1N51_RS09275	COG0517	IMP dehydrogenase activity
C1N51_RS09285	COG1127	ABC transporter
C1N51_RS09290	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C1N51_RS09295	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C1N51_RS09300	COG2854	intermembrane phospholipid transfer
C1N51_RS09310	COG5007	Belongs to the BolA IbaG family
C1N51_RS09320	COG0204	Acyl-transferase
C1N51_RS09325	COG0251	oxidation-reduction process
C1N51_RS09365	COG0456	acetyltransferase
C1N51_RS09375	COG0525	valine-tRNA ligase activity
C1N51_RS09380	COG2927	DNA polymerase III (CHI subunit)
C1N51_RS09390	COG0795	lipopolysaccharide-transporting ATPase activity
C1N51_RS09395	COG0795	lipopolysaccharide-transporting ATPase activity
C1N51_RS09405	COG1028	Short-chain dehydrogenase reductase Sdr
C1N51_RS09415	COG0726	polysaccharide deacetylase
C1N51_RS09420	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C1N51_RS09430	COG1447	Phosphotransferase system cellobiose-specific component IIA
C1N51_RS09435	COG1486	melibiose metabolic process
C1N51_RS09445	COG1609	Transcriptional regulator
C1N51_RS09450	COG3437	response regulator, receiver
C1N51_RS09505	COG1012	belongs to the aldehyde dehydrogenase family
C1N51_RS09605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C1N51_RS09610	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C1N51_RS09625	COG0762	integral membrane protein
C1N51_RS09630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C1N51_RS09635	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C1N51_RS09650	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C1N51_RS09655	COG1678	Uncharacterized ACR, COG1678
C1N51_RS09660	COG0189	ligase activity
C1N51_RS09665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C1N51_RS09670	COG2356	endonuclease I
C1N51_RS09690	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C1N51_RS09710	COG0191	fructose-bisphosphate aldolase activity
C1N51_RS09715	COG0668	transmembrane transport
C1N51_RS09730	COG0583	DNA-binding transcription factor activity
C1N51_RS09740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1N51_RS09750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C1N51_RS09760	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C1N51_RS09775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1N51_RS09780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1N51_RS09785	COG2433	Pfam Transposase IS66
C1N51_RS09815	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C1N51_RS09825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C1N51_RS09830	COG1595	DNA-templated transcription, initiation
C1N51_RS09845	COG3086	response to oxidative stress
C1N51_RS09865	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C1N51_RS09870	COG1381	Involved in DNA repair and RecF pathway recombination
C1N51_RS09875	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C1N51_RS09900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C1N51_RS09905	COG3956	TIGRFAM MazG family protein
C1N51_RS09915	COG0148	phosphopyruvate hydratase activity
C1N51_RS09925	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C1N51_RS09955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C1N51_RS09965	COG1546	Belongs to the CinA family
C1N51_RS09970	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C1N51_RS09985	COG0527	aspartate kinase activity
C1N51_RS10045	COG3630	sodium ion export across plasma membrane
C1N51_RS10050	COG0511	ligase activity, forming carbon-carbon bonds
C1N51_RS10050	COG5016	pyruvate
C1N51_RS10055	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
C1N51_RS10065	COG1238	metal cluster binding
C1N51_RS10070	COG0612	Peptidase, M16
C1N51_RS10090	COG4536	flavin adenine dinucleotide binding
C1N51_RS10095	COG4137	Cytochrome C assembly protein
C1N51_RS10100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C1N51_RS10125	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C1N51_RS10130	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
C1N51_RS10135	COG0237	dephospho-CoA kinase activity
C1N51_RS10145	COG1459	type II secretion system
C1N51_RS10150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1N51_RS10175	COG2186	Transcriptional regulator
C1N51_RS10180	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C1N51_RS10185	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N51_RS10190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1N51_RS10210	COG0288	reversible hydration of carbon dioxide
C1N51_RS10215	COG0659	secondary active sulfate transmembrane transporter activity
C1N51_RS10220	COG1131	(ABC) transporter
C1N51_RS10225	COG0842	Transport permease protein
C1N51_RS10230	COG1560	Kdo2-lipid A biosynthetic process
C1N51_RS10245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C1N51_RS10260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C1N51_RS10275	COG1643	Atp-dependent helicase
C1N51_RS10280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1N51_RS10285	COG1752	Esterase of the alpha-beta hydrolase superfamily
C1N51_RS10290	COG1049	propionate catabolic process, 2-methylcitrate cycle
C1N51_RS10310	COG0004	ammonium transporteR
C1N51_RS10315	COG1840	ABC-type Fe3 transport system, periplasmic component
C1N51_RS10325	COG3842	ATPase activity
C1N51_RS10330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1N51_RS10345	COG2971	BadF BadG BcrA BcrD
C1N51_RS10355	COG4608	Belongs to the ABC transporter superfamily
C1N51_RS10360	COG0444	Belongs to the ABC transporter superfamily
C1N51_RS10365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N51_RS10375	COG0747	negative chemotaxis
C1N51_RS10380	COG2205	protein histidine kinase activity
C1N51_RS10380	COG2198	Histidine kinase
C1N51_RS10380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N51_RS10380	COG0784	Response regulator, receiver
C1N51_RS10395	COG0628	permease
C1N51_RS10415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N51_RS10420	COG0739	heme binding
C1N51_RS10425	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C1N51_RS10435	COG2027	D-alanyl-D-alanine carboxypeptidase
C1N51_RS10440	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C1N51_RS10445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1N51_RS10450	COG1534	Rna-binding protein
C1N51_RS10460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C1N51_RS10465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C1N51_RS10480	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C1N51_RS10500	COG0195	Participates in both transcription termination and antitermination
C1N51_RS10520	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C1N51_RS10540	COG0534	Mate efflux family protein
C1N51_RS10545	COG0826	peptidase U32
C1N51_RS10550	COG0826	peptidase U32
C1N51_RS10560	COG3154	lipid carrier protein
C1N51_RS10565	COG3153	acetyltransferase
C1N51_RS10585	COG3706	GGDEF domain
C1N51_RS10595	COG0084	hydrolase, TatD family'
C1N51_RS10600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1N51_RS10610	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C1N51_RS10620	COG0813	purine-nucleoside phosphorylase activity
C1N51_RS10630	COG0560	Phosphoserine phosphatase
C1N51_RS10640	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C1N51_RS10645	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C1N51_RS10675	COG1022	Amp-dependent synthetase and ligase
C1N51_RS10680	COG2169	Transcriptional regulator
C1N51_RS10705	COG4964	Belongs to the GSP D family
C1N51_RS10770	COG0583	DNA-binding transcription factor activity
C1N51_RS10775	COG0531	amino acid
C1N51_RS10780	COG2731	YhcH YjgK YiaL family protein
C1N51_RS10785	COG3250	beta-galactosidase activity
C1N51_RS10790	COG1609	Transcriptional regulator
C1N51_RS10795	COG0768	penicillin binding
C1N51_RS10800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1N51_RS10805	COG1085	galactose-1-phosphate uridylyltransferase
C1N51_RS10815	COG2017	converts alpha-aldose to the beta-anomer
C1N51_RS10820	COG1609	Transcriptional regulator
C1N51_RS10830	COG2211	Major facilitator Superfamily
C1N51_RS10835	COG1609	Transcriptional regulator
C1N51_RS10850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1N51_RS10870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C1N51_RS10875	COG1349	DNA-binding transcription factor activity
C1N51_RS10885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C1N51_RS10895	COG2271	Major facilitator Superfamily
C1N51_RS10900	COG0584	glycerophosphoryl diester phosphodiesterase
C1N51_RS10905	COG2433	Pfam Transposase IS66
C1N51_RS10930	COG2171	N-acyltransferase activity
C1N51_RS10945	COG3141	response to X-ray
C1N51_RS10965	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C1N51_RS10970	COG1074	ATP-dependent DNA helicase activity
C1N51_RS10975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C1N51_RS10985	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C1N51_RS10985	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C1N51_RS11000	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C1N51_RS11005	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C1N51_RS11010	COG2166	iron-sulfur cluster assembly
C1N51_RS11015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C1N51_RS11020	COG0693	protein deglycase activity
C1N51_RS11025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C1N51_RS11050	COG1595	DNA-templated transcription, initiation
C1N51_RS11080	COG0271	Belongs to the BolA IbaG family
C1N51_RS11115	COG1477	protein flavinylation
C1N51_RS11130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C1N51_RS11135	COG0514	ATP-dependent DNA helicase (RecQ)
C1N51_RS11140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1N51_RS11155	COG0733	neurotransmitter:sodium symporter activity
C1N51_RS11180	COG1720	tRNA m6t6A37 methyltransferase activity
C1N51_RS11195	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C1N51_RS11230	COG0564	pseudouridine synthase activity
C1N51_RS11245	COG0024	Methionine aminopeptidase
C1N51_RS11270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C1N51_RS11275	COG0575	Belongs to the CDS family
C1N51_RS11285	COG0750	zinc metalloprotease
C1N51_RS11295	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C1N51_RS11300	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C1N51_RS11325	COG0587	DNA-directed DNA polymerase activity
C1N51_RS11360	COG2433	Pfam Transposase IS66
C1N51_RS11385	COG0347	Belongs to the P(II) protein family
C1N51_RS11400	COG0741	lytic transglycosylase activity
C1N51_RS11400	COG1388	LysM domain
C1N51_RS11410	COG2226	methyltransferase
C1N51_RS11420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C1N51_RS11440	COG1960	acyl-CoA dehydrogenase activity
C1N51_RS11445	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C1N51_RS11450	COG0121	glutamine amidotransferase
C1N51_RS11455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C1N51_RS11460	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C1N51_RS11465	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C1N51_RS11470	COG2233	PERMEase
C1N51_RS11490	COG1393	Belongs to the ArsC family
C1N51_RS11495	COG4783	chaperone-mediated protein folding
C1N51_RS11510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C1N51_RS11515	COG2716	regulation of RNA biosynthetic process
C1N51_RS11520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C1N51_RS11525	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C1N51_RS11545	COG1393	Belongs to the ArsC family
C1N51_RS11570	COG2837	iron assimilation
C1N51_RS11575	COG2169	Transcriptional regulator
C1N51_RS11580	COG1486	melibiose metabolic process
C1N51_RS11585	COG2211	Major facilitator Superfamily
C1N51_RS11595	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N51_RS11605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N51_RS11610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N51_RS11615	COG1334	flagellar protein FlaG
C1N51_RS11620	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C1N51_RS11630	COG1516	flagellar protein fliS
C1N51_RS11650	COG1677	Flagellar hook-basal body complex protein FliE
C1N51_RS11660	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C1N51_RS11715	COG1987	bacterial-type flagellum assembly
C1N51_RS11720	COG1684	flagellar biosynthetic protein fliR
C1N51_RS11755	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C1N51_RS11760	COG0643	Histidine kinase
C1N51_RS11760	COG0784	Response regulator, receiver
C1N51_RS11760	COG2198	Histidine kinase
C1N51_RS11765	COG2201	protein-glutamate methylesterase activity
C1N51_RS11770	COG1192	Involved in chromosome partitioning
C1N51_RS11780	COG0835	chemotaxis
C1N51_RS11790	COG4133	protoheme IX ABC transporter activity
C1N51_RS11795	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1N51_RS11800	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1N51_RS11815	COG1138	Cytochrome C-type biogenesis protein
C1N51_RS11820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1N51_RS11830	COG4235	cytochrome complex assembly
C1N51_RS11830	COG3088	subunit of a heme lyase
C1N51_RS11835	COG2853	Lipoprotein
C1N51_RS11840	COG2067	long-chain fatty acid transport protein
C1N51_RS11845	COG2067	long-chain fatty acid transport protein
C1N51_RS11865	COG0183	Belongs to the thiolase family
C1N51_RS11885	COG2062	phosphohistidine phosphatase, SixA
C1N51_RS11895	COG2890	protein-(glutamine-N5) methyltransferase activity
C1N51_RS11905	COG2860	membrane
C1N51_RS11910	COG3101	peptidyl-lysine hydroxylation
C1N51_RS11930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1N51_RS11940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1N51_RS11945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C1N51_RS11970	COG0285	dihydrofolate synthase activity
C1N51_RS11975	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C1N51_RS11980	COG1286	toxin biosynthetic process
C1N51_RS11985	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C1N51_RS11990	COG0583	DNA-binding transcription factor activity
C1N51_RS11995	COG0745	RESPONSE REGULATOR receiver
C1N51_RS12005	COG2832	Protein of unknown function (DUF454)
C1N51_RS12015	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C1N51_RS12025	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C1N51_RS12030	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C1N51_RS12035	COG0814	amino acid
C1N51_RS12040	COG0251	oxidation-reduction process
C1N51_RS12050	COG2964	Protein conserved in bacteria
C1N51_RS12085	COG0194	GDP metabolic process
C1N51_RS12105	COG1196	nuclear chromosome segregation
C1N51_RS12140	COG0210	DNA helicase
C1N51_RS12185	COG2983	Belongs to the UPF0260 family
C1N51_RS12190	COG2261	transglycosylase associated protein
C1N51_RS12195	COG2985	domain, Protein
C1N51_RS12200	COG0076	glutamate decarboxylase activity
C1N51_RS12210	COG0668	transmembrane transport
C1N51_RS12220	COG0346	lactoylglutathione lyase activity
C1N51_RS12230	COG1785	Belongs to the alkaline phosphatase family
C1N51_RS12250	COG2226	methyltransferase
C1N51_RS12270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C1N51_RS12275	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N51_RS12285	COG3139	Protein of unknown function (DUF1315)
C1N51_RS12290	COG0252	asparaginase activity
C1N51_RS12295	COG0616	signal peptide processing
C1N51_RS12300	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1N51_RS12300	COG1902	pentaerythritol trinitrate reductase activity
C1N51_RS12305	COG0778	Nitroreductase
C1N51_RS12310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1N51_RS12325	COG0123	including yeast histone deacetylase and acetoin utilization protein
C1N51_RS12335	COG4269	membrane
C1N51_RS12350	COG3083	sulfuric ester hydrolase activity
C1N51_RS12375	COG1757	Na H antiporter
C1N51_RS12380	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C1N51_RS12385	COG2165	general secretion pathway protein
C1N51_RS12390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1N51_RS12395	COG2095	MarC family integral membrane protein
C1N51_RS12400	COG1454	alcohol dehydrogenase
C1N51_RS12400	COG1012	belongs to the aldehyde dehydrogenase family
C1N51_RS12405	COG1028	Short-chain dehydrogenase reductase Sdr
C1N51_RS12420	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C1N51_RS12430	COG2056	Na+-H+ antiporter family
C1N51_RS12440	COG2885	chlorophyll binding
C1N51_RS12450	COG0346	lactoylglutathione lyase activity
C1N51_RS12455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C1N51_RS12460	COG4660	Part of a membrane complex involved in electron transport
C1N51_RS12465	COG4659	FMN binding
C1N51_RS12470	COG4658	electron transport chain
C1N51_RS12475	COG4656	Part of a membrane complex involved in electron transport
C1N51_RS12485	COG4657	Part of a membrane complex involved in electron transport
C1N51_RS12500	COG0745	RESPONSE REGULATOR receiver
C1N51_RS12535	COG0556	nucleotide-excision repair
C1N51_RS12550	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C1N51_RS12555	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C1N51_RS12560	COG0521	Mo-molybdopterin cofactor biosynthetic process
C1N51_RS12570	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C1N51_RS12575	COG0314	molybdopterin synthase activity
C1N51_RS12585	COG0601	transmembrane transport
C1N51_RS12590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N51_RS12595	COG0444	Belongs to the ABC transporter superfamily
C1N51_RS12605	COG0435	Glutathione S-transferase
C1N51_RS12610	COG3174	membrane
C1N51_RS12615	COG0280	phosphate acetyltransferase
C1N51_RS12615	COG0857	belongs to the CobB CobQ family
C1N51_RS12640	COG4120	Belongs to the binding-protein-dependent transport system permease family
C1N51_RS12645	COG1122	ATPase activity
C1N51_RS12670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1N51_RS12675	COG0653	protein targeting
C1N51_RS12680	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C1N51_RS12690	COG2186	Transcriptional regulator
C1N51_RS12720	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C1N51_RS12725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N51_RS12730	COG0659	secondary active sulfate transmembrane transporter activity
C1N51_RS12740	COG1530	ribonuclease E activity
C1N51_RS12745	COG0564	pseudouridine synthase activity
C1N51_RS12750	COG0424	maF-like protein
C1N51_RS12755	COG1399	metal-binding, possibly nucleic acid-binding protein
C1N51_RS12770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1N51_RS12800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C1N51_RS12815	COG0084	hydrolase, TatD family'
C1N51_RS12820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N51_RS12820	COG1263	PTS System
C1N51_RS12835	COG0733	neurotransmitter:sodium symporter activity
C1N51_RS12850	COG4667	esterase of the alpha-beta hydrolase superfamily
C1N51_RS12875	COG2272	Belongs to the type-B carboxylesterase lipase family
C1N51_RS12885	COG3710	Transcriptional regulator
C1N51_RS12885	COG0457	Tetratricopeptide repeat
C1N51_RS12915	COG2433	Pfam Transposase IS66
C1N51_RS12955	COG1940	carbohydrate kinase activity
C1N51_RS12960	COG0784	Response regulator, receiver
C1N51_RS12960	COG0835	chemotaxis
C1N51_RS12980	COG1028	Short-chain dehydrogenase reductase Sdr
C1N51_RS12985	COG0616	signal peptide processing
C1N51_RS12995	COG0539	negative regulation of cytoplasmic translation
C1N51_RS13005	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C1N51_RS13010	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C1N51_RS13020	COG4166	transmembrane transport
C1N51_RS13040	COG3009	Protein conserved in bacteria
C1N51_RS13045	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C1N51_RS13045	COG3008	intermembrane lipid transfer
C1N51_RS13050	COG2995	paraquat-inducible protein a
C1N51_RS13055	COG1609	Transcriptional regulator
C1N51_RS13060	COG3250	beta-galactosidase activity
C1N51_RS13070	COG4580	involved in the transport of maltose and maltodextrins
C1N51_RS13085	COG2211	Major facilitator Superfamily
C1N51_RS13100	COG4232	protein-disulfide reductase activity
C1N51_RS13105	COG3118	belongs to the thioredoxin family
C1N51_RS13135	COG1132	(ABC) transporter
C1N51_RS13150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N51_RS13165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N51_RS13175	COG0577	efflux transmembrane transporter activity
C1N51_RS13180	COG0577	efflux transmembrane transporter activity
C1N51_RS13180	COG1136	(ABC) transporter
C1N51_RS13185	COG1136	(ABC) transporter
C1N51_RS13185	COG0577	efflux transmembrane transporter activity
C1N51_RS13200	COG2176	DNA-directed DNA polymerase activity
C1N51_RS13275	COG5002	protein histidine kinase activity
C1N51_RS13275	COG3850	Histidine kinase
C1N51_RS13280	COG0745	RESPONSE REGULATOR receiver
C1N51_RS13285	COG0463	Glycosyl transferase, family 2
C1N51_RS13290	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C1N51_RS13300	COG0840	transmembrane signaling receptor activity
C1N51_RS13305	COG2175	clavaminate synthase activity
C1N51_RS13310	COG2964	Protein conserved in bacteria
C1N51_RS13315	COG0251	oxidation-reduction process
C1N51_RS13325	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1N51_RS13345	COG2433	Pfam Transposase IS66
C1N51_RS13360	COG1032	radical SAM domain protein
C1N51_RS13365	COG5001	Diguanylate cyclase
C1N51_RS13365	COG1716	ATPase activity
C1N51_RS13395	COG2350	Protein conserved in bacteria
C1N51_RS13410	COG2433	Pfam Transposase IS66
C1N51_RS13460	COG1301	dicarboxylic acid transport
C1N51_RS13465	COG0159	tryptophan synthase activity
C1N51_RS13475	COG0135	phosphoribosylanthranilate isomerase activity
C1N51_RS13475	COG0134	indole-3-glycerol-phosphate synthase activity
C1N51_RS13485	COG0512	Glutamine amidotransferase of anthranilate synthase
C1N51_RS13490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1N51_RS13500	COG0613	PHP domain protein
C1N51_RS13505	COG0009	L-threonylcarbamoyladenylate synthase
C1N51_RS13515	COG1187	pseudouridine synthase activity
C1N51_RS13535	COG0417	DNA replication proofreading
C1N51_RS13540	COG2197	response regulator
C1N51_RS13545	COG0322	excinuclease ABC activity
C1N51_RS13585	COG0019	diaminopimelate decarboxylase activity
C1N51_RS13600	COG1546	Belongs to the CinA family
C1N51_RS13600	COG1058	Belongs to the CinA family
C1N51_RS13610	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1N51_RS13615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1N51_RS13640	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C1N51_RS13650	COG0437	4 iron, 4 sulfur cluster binding
C1N51_RS13655	COG3301	Polysulphide reductase, NrfD
C1N51_RS13660	COG1138	Cytochrome C-type biogenesis protein
C1N51_RS13670	COG3088	subunit of a heme lyase
C1N51_RS13670	COG4235	cytochrome complex assembly
C1N51_RS13705	COG2989	Protein conserved in bacteria
C1N51_RS13710	COG3108	Peptidase M15
C1N51_RS13715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1N51_RS13730	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C1N51_RS13755	COG1846	Transcriptional regulator
C1N51_RS13760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1N51_RS13785	COG1448	Aminotransferase
C1N51_RS13805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N51_RS13820	COG0017	Asparaginyl-tRNA synthetase
C1N51_RS13830	COG0720	synthase
C1N51_RS13835	COG2197	response regulator
C1N51_RS13850	COG1760	l-serine dehydratase
C1N51_RS13855	COG0814	amino acid
C1N51_RS13870	COG2205	protein histidine kinase activity
C1N51_RS13870	COG0784	Response regulator, receiver
C1N51_RS13875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1N51_RS13890	COG3106	COG3106 Predicted ATPase
C1N51_RS13905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N51_RS13925	COG2433	Pfam Transposase IS66
C1N51_RS14045	COG2801	Transposase and inactivated derivatives
C1N51_RS14075	COG2801	Transposase and inactivated derivatives
C1N51_RS14190	COG2433	Pfam Transposase IS66
C1N51_RS14255	COG0494	nUDIX hydrolase
C1N51_RS14260	COG1714	RDD family
C1N51_RS14275	COG2801	Transposase and inactivated derivatives
C1N51_RS14300	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1N51_RS14330	COG2433	Pfam Transposase IS66
C1N51_RS14450	COG1403	HNH endonuclease
C1N51_RS14495	COG3335	DDE superfamily endonuclease
C1N51_RS14570	COG4221	oxidoreductase activity
C1N51_RS14585	COG3340	Belongs to the peptidase S51 family
C1N51_RS14615	COG0456	acetyltransferase
C1N51_RS14620	COG0471	metal ion transport
C1N51_RS14625	COG4191	Histidine kinase
C1N51_RS14625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N51_RS14650	COG1328	CTP reductase activity
C1N51_RS14655	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1N51_RS14665	COG0861	Integral membrane protein TerC family
C1N51_RS14675	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C1N51_RS14680	COG4221	oxidoreductase activity
C1N51_RS14685	COG1454	alcohol dehydrogenase
C1N51_RS14690	COG0814	amino acid
C1N51_RS14710	COG1132	(ABC) transporter
C1N51_RS14715	COG1132	(ABC) transporter
C1N51_RS14720	COG2165	general secretion pathway protein
C1N51_RS14735	COG0443	Heat shock 70 kDa protein
C1N51_RS14740	COG0443	Heat shock 70 kDa protein
C1N51_RS14750	COG3706	GGDEF domain
C1N51_RS14780	COG3227	Zinc metalloprotease (Elastase)
C1N51_RS14800	COG3842	ATPase activity
C1N51_RS14805	COG3459	Glycosyltransferase 36 associated
C1N51_RS14815	COG1653	transport
C1N51_RS14825	COG0395	ABC-type sugar transport system, permease component
C1N51_RS14840	COG0243	molybdopterin cofactor binding
C1N51_RS14845	COG0437	4 iron, 4 sulfur cluster binding
C1N51_RS14850	COG3302	dmso reductase anchor subunit
C1N51_RS14865	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C1N51_RS14870	COG1643	Atp-dependent helicase
C1N51_RS14895	COG3063	Type IV pilus biogenesis stability protein PilW
C1N51_RS14905	COG3335	DDE superfamily endonuclease
C1N51_RS14930	COG0531	amino acid
C1N51_RS14935	COG1280	lysine exporter protein (LysE YggA)
C1N51_RS14940	COG1560	Kdo2-lipid A biosynthetic process
C1N51_RS14965	COG1280	lysine exporter protein (LysE YggA)
C1N51_RS15000	COG1115	amino acid carrier protein
C1N51_RS15025	COG1368	sulfuric ester hydrolase activity
C1N51_RS15030	COG0215	cysteine-tRNA ligase activity
C1N51_RS15035	COG0534	Mate efflux family protein
C1N51_RS15040	COG3335	DDE superfamily endonuclease
C1N51_RS15045	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C1N51_RS15055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1N51_RS15060	COG0456	acetyltransferase
C1N51_RS15065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C1N51_RS15070	COG0662	Cupin 2, conserved barrel domain protein
C1N51_RS15075	COG0527	aspartate kinase activity
C1N51_RS15085	COG1858	cytochrome C peroxidase
C1N51_RS15090	COG1404	Belongs to the peptidase S8 family
C1N51_RS15095	COG3227	Zinc metalloprotease (Elastase)
C1N51_RS15135	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C1N51_RS15140	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
C1N51_RS15160	COG3385	transposase activity
C1N51_RS15175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N51_RS15190	COG3290	protein histidine kinase activity
C1N51_RS15195	COG4565	transcriptional regulatory protein
C1N51_RS15200	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C1N51_RS15205	COG0363	glucosamine-6-phosphate deaminase activity
C1N51_RS15210	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C1N51_RS15240	COG3284	Transcriptional regulator
C1N51_RS15245	COG1012	belongs to the aldehyde dehydrogenase family
C1N51_RS15250	COG2358	TRAP transporter, solute receptor (TAXI family
C1N51_RS15255	COG0730	response to heat
C1N51_RS15285	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C1N51_RS15290	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C1N51_RS15400	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C1N51_RS15405	COG0372	Belongs to the citrate synthase family
C1N51_RS15415	COG2828	Protein conserved in bacteria
C1N51_RS15450	COG0561	phosphatase activity
C1N51_RS15455	COG0602	queuosine metabolic process
C1N51_RS15465	COG3706	GGDEF domain
C1N51_RS15520	COG0840	transmembrane signaling receptor activity
C1N51_RS15525	COG1254	Belongs to the acylphosphatase family
C1N51_RS15530	COG2920	part of a sulfur-relay system
C1N51_RS15540	COG0670	Belongs to the BI1 family
C1N51_RS15545	COG1126	abc transporter atp-binding protein
C1N51_RS15550	COG0765	amino acid transport
C1N51_RS15555	COG4597	amino acid ABC transporter
C1N51_RS15560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N51_RS15580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1N51_RS15605	COG3008	intermembrane lipid transfer
C1N51_RS15610	COG2995	paraquat-inducible protein a
C1N51_RS15615	COG1132	(ABC) transporter
C1N51_RS15620	COG1956	GAF domain-containing protein
C1N51_RS15625	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C1N51_RS15640	COG0308	aminopeptidase N
C1N51_RS15650	COG2902	Dehydrogenase
C1N51_RS15665	COG2433	Pfam Transposase IS66
C1N51_RS15690	COG0488	(ABC) transporter
C1N51_RS15710	COG1067	ATP-dependent peptidase activity
C1N51_RS15750	COG3278	Belongs to the heme-copper respiratory oxidase family
C1N51_RS15765	COG2010	Cytochrome c
C1N51_RS15775	COG2217	Heavy metal translocating P-type atpase
C1N51_RS15790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1N51_RS15795	COG0589	response to stress
C1N51_RS15820	COG3842	ATPase activity
C1N51_RS15830	COG1177	transmembrane transport
C1N51_RS15840	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C1N51_RS15845	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C1N51_RS15865	COG0437	4 iron, 4 sulfur cluster binding
C1N51_RS15870	COG0243	molybdopterin cofactor binding
C1N51_RS15870	COG3383	formate dehydrogenase (NAD+) activity
C1N51_RS15880	COG3381	protein complex oligomerization
C1N51_RS15900	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C1N51_RS15915	COG0488	(ABC) transporter
C1N51_RS15935	COG4191	Histidine kinase
C1N51_RS15940	COG2204	response regulator
C1N51_RS15950	COG4662	Binding-protein-dependent transport system inner membrane component
C1N51_RS15955	COG3842	ATPase activity
C1N51_RS15965	COG0303	'Molybdopterin
C1N51_RS15975	COG1940	carbohydrate kinase activity
C1N51_RS15980	COG3148	PFAM DTW domain containing protein
C1N51_RS16020	COG0494	nUDIX hydrolase
C1N51_RS16025	COG0840	transmembrane signaling receptor activity
C1N51_RS16030	COG0791	NLP P60 protein
C1N51_RS16040	COG3706	GGDEF domain
C1N51_RS16045	COG2201	protein-glutamate methylesterase activity
C1N51_RS16050	COG3001	Fructosamine kinase
C1N51_RS16060	COG0307	riboflavin synthase, alpha
C1N51_RS16065	COG0534	Mate efflux family protein
C1N51_RS16075	COG1793	dna ligase
C1N51_RS16085	COG2885	chlorophyll binding
C1N51_RS16105	COG2204	response regulator
C1N51_RS16110	COG0438	transferase activity, transferring glycosyl groups
C1N51_RS16115	COG0438	transferase activity, transferring glycosyl groups
C1N51_RS16145	COG0438	transferase activity, transferring glycosyl groups
C1N51_RS16150	COG1215	transferase activity, transferring glycosyl groups
C1N51_RS16155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C1N51_RS16165	COG3064	Membrane
C1N51_RS16200	COG5001	Diguanylate cyclase
C1N51_RS16200	COG3300	MHYT domain
C1N51_RS16205	COG3437	response regulator, receiver
C1N51_RS16205	COG3850	Histidine kinase
C1N51_RS16205	COG2205	protein histidine kinase activity
C1N51_RS16205	COG4999	Histidine kinase
C1N51_RS16225	COG0110	maltose O-acetyltransferase activity
C1N51_RS16250	COG1846	Transcriptional regulator
C1N51_RS16265	COG3247	response to pH
C1N51_RS16270	COG0668	transmembrane transport
C1N51_RS16280	COG1404	Belongs to the peptidase S8 family
C1N51_RS16290	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C1N51_RS16305	COG0745	RESPONSE REGULATOR receiver
C1N51_RS16355	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C1N51_RS16355	COG2199	diguanylate cyclase activity
C1N51_RS16390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N51_RS16405	COG0786	glutamate:sodium symporter activity
C1N51_RS16430	COG0625	glutathione transferase activity
C1N51_RS16440	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
C1N51_RS16455	COG2195	Cleaves the N-terminal amino acid of tripeptides
C1N51_RS16500	COG0813	purine-nucleoside phosphorylase activity
C1N51_RS16520	COG3335	DDE superfamily endonuclease
C1N51_RS16535	COG1451	nucleotide metabolic process
C1N51_RS16545	COG5492	domain, Protein
C1N51_RS16545	COG4932	domain protein
C1N51_RS16555	COG2165	general secretion pathway protein
C1N51_RS16590	COG0583	DNA-binding transcription factor activity
C1N51_RS16620	COG4139	cobalamin transport
C1N51_RS16635	COG2062	phosphohistidine phosphatase, SixA
C1N51_RS16645	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C1N51_RS16655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C1N51_RS16660	COG0702	epimerase
C1N51_RS16665	COG1823	symporter activity
C1N51_RS16675	COG2925	Exonuclease
C1N51_RS16685	COG1346	cytolysis
C1N51_RS16735	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N51_RS16740	COG4605	iron ion homeostasis
C1N51_RS16745	COG4607	ABC-type enterochelin transport system periplasmic component
C1N51_RS16750	COG4774	siderophore transport
C1N51_RS16770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1N51_RS16780	COG1132	(ABC) transporter
C1N51_RS16780	COG2375	cellular response to nickel ion
C1N51_RS16785	COG1132	(ABC) transporter
C1N51_RS16790	COG1535	isochorismatase
C1N51_RS16790	COG3433	isochorismatase activity
C1N51_RS16795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1N51_RS16795	COG0072	phenylalanine-tRNA ligase activity
C1N51_RS16805	COG3706	GGDEF domain
C1N51_RS16845	COG0251	oxidation-reduction process
C1N51_RS16885	COG2188	Transcriptional regulator
C1N51_RS16895	COG0010	Belongs to the arginase family
C1N51_RS16905	COG2986	histidine ammonia-lyase
C1N51_RS16950	COG0277	FAD linked oxidase domain protein
C1N51_RS16950	COG0247	lactate metabolic process
C1N51_RS17010	COG1643	Atp-dependent helicase
C1N51_RS17020	COG2949	membrane
C1N51_RS17025	COG0471	metal ion transport
C1N51_RS17030	COG3706	GGDEF domain
C1N51_RS17050	COG0492	ferredoxin-NADP+ reductase activity
C1N51_RS17055	COG4988	ABC transporter
C1N51_RS17060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C1N51_RS17070	COG0583	DNA-binding transcription factor activity
C1N51_RS17075	COG2200	EAL domain
C1N51_RS17105	COG5001	Diguanylate cyclase
C1N51_RS17115	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C1N51_RS17125	COG4191	Histidine kinase
C1N51_RS17125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N51_RS17140	COG3070	regulator of competence-specific genes
C1N51_RS17155	COG2431	L-lysine efflux transmembrane transporter activity
C1N51_RS17165	COG0076	glutamate decarboxylase activity
C1N51_RS17170	COG1737	Transcriptional regulator
C1N51_RS17185	COG2433	Pfam Transposase IS66
C1N51_RS17195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C1N51_RS17205	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C1N51_RS17235	COG4181	ATPase activity
C1N51_RS17240	COG0534	Mate efflux family protein
C1N51_RS17245	COG0702	epimerase
C1N51_RS17250	COG4667	esterase of the alpha-beta hydrolase superfamily
C1N51_RS17260	COG2814	Major facilitator Superfamily
C1N51_RS17265	COG1187	pseudouridine synthase activity
C1N51_RS17270	COG1061	Type III restriction enzyme res subunit
C1N51_RS17275	COG3706	GGDEF domain
C1N51_RS17335	COG3313	Fe-S protein
C1N51_RS17360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C1N51_RS17370	COG0584	glycerophosphoryl diester phosphodiesterase
C1N51_RS17375	COG0745	RESPONSE REGULATOR receiver
C1N51_RS17395	COG0811	peptide transport
C1N51_RS17400	COG0811	peptide transport
C1N51_RS17405	COG0848	biopolymer transport protein
C1N51_RS17450	COG0803	Belongs to the bacterial solute-binding protein 9 family
C1N51_RS17455	COG1121	(ABC) transporter
C1N51_RS17460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1N51_RS17475	COG1770	oligopeptidase
C1N51_RS17480	COG2814	Major facilitator Superfamily
C1N51_RS17485	COG0010	Belongs to the arginase family
C1N51_RS17490	COG1166	arginine decarboxylase activity
C1N51_RS17500	COG4067	protein conserved in archaea
C1N51_RS17500	COG0189	ligase activity
C1N51_RS17505	COG0189	ligase activity
C1N51_RS17515	COG0583	DNA-binding transcription factor activity
C1N51_RS17555	COG1114	Component of the transport system for branched-chain amino acids
C1N51_RS17575	COG0579	oxidoreductase
C1N51_RS17580	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C1N51_RS17595	COG3033	Beta-eliminating lyase
C1N51_RS17615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1N51_RS17620	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1N51_RS17655	COG3706	GGDEF domain
C1N51_RS17660	COG0415	Belongs to the DNA photolyase family
C1N51_RS17665	COG3046	protein related to deoxyribodipyrimidine photolyase
C1N51_RS17680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N51_RS17680	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N51_RS17685	COG1765	OsmC-like protein
C1N51_RS17715	COG1011	Hydrolase
C1N51_RS17740	COG3240	lipase activity
C1N51_RS17760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C1N51_RS17770	COG1840	ABC-type Fe3 transport system, periplasmic component
C1N51_RS17780	COG3842	ATPase activity
C1N51_RS17805	COG2990	Protein conserved in bacteria
C1N51_RS17815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1N51_RS17820	COG2866	Carboxypeptidase
C1N51_RS17830	COG0583	DNA-binding transcription factor activity
C1N51_RS17855	COG3104	oligopeptide transport
C1N51_RS17860	COG1760	l-serine dehydratase
C1N51_RS17885	COG0741	lytic transglycosylase activity
C1N51_RS17885	COG1388	LysM domain
C1N51_RS17905	COG1815	bacterial-type flagellum-dependent cell motility
C1N51_RS17910	COG1558	bacterial-type flagellum-dependent cell motility
C1N51_RS17915	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C1N51_RS17920	COG1749	Flagellar hook protein flgE
C1N51_RS17925	COG4787	bacterial-type flagellum-dependent cell motility
C1N51_RS17930	COG4786	Flagellar basal body rod
C1N51_RS17935	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C1N51_RS17940	COG1706	bacterial-type flagellum-dependent cell motility
C1N51_RS17950	COG1256	bacterial-type flagellum assembly
C1N51_RS17950	COG4786	Flagellar basal body rod
C1N51_RS17955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N51_RS17990	COG1522	sequence-specific DNA binding
C1N51_RS18000	COG1473	amidohydrolase
C1N51_RS18005	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1N51_RS18015	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1N51_RS18065	COG0384	phenazine biosynthesis protein PhzF
C1N51_RS18090	COG1360	Flagellar Motor Protein
C1N51_RS18095	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C1N51_RS18100	COG1191	sigma factor activity
C1N51_RS18105	COG1580	Controls the rotational direction of flagella during chemotaxis
C1N51_RS18120	COG1516	flagellar protein fliS
C1N51_RS18125	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C1N51_RS18135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1N51_RS18150	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C1N51_RS18160	COG1987	bacterial-type flagellum assembly
C1N51_RS18220	COG2200	EAL domain
C1N51_RS18315	COG0346	lactoylglutathione lyase activity
C1N51_RS18340	COG0745	RESPONSE REGULATOR receiver
C1N51_RS18365	COG0156	8-amino-7-oxononanoate synthase activity
C1N51_RS18370	COG1063	alcohol dehydrogenase
C1N51_RS18395	COG2199	diguanylate cyclase activity
C1N51_RS18400	COG2223	nitrite transmembrane transporter activity
C1N51_RS18405	COG1063	alcohol dehydrogenase
C1N51_RS18415	COG0668	transmembrane transport
C1N51_RS18425	COG1304	FMN binding
C1N51_RS18430	COG1620	l-lactate permease
C1N51_RS18435	COG0583	DNA-binding transcription factor activity
C1N51_RS18440	COG1505	serine-type exopeptidase activity
C1N51_RS18445	COG4172	Belongs to the ABC transporter superfamily
C1N51_RS18455	COG1067	ATP-dependent peptidase activity
C1N51_RS18465	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C1N51_RS18485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N51_RS18490	COG0437	4 iron, 4 sulfur cluster binding
C1N51_RS18495	COG0348	domain, Protein
C1N51_RS18515	COG1122	ATPase activity
C1N51_RS18525	COG1566	PFAM secretion protein HlyD family protein
C1N51_RS18550	COG2433	Pfam Transposase IS66
C1N51_RS18570	COG0813	purine-nucleoside phosphorylase activity
C1N51_RS18580	COG3272	Protein of unknown function (DUF1722)
C1N51_RS18585	COG0789	Transcriptional regulator
C1N51_RS18590	COG0415	Belongs to the DNA photolyase family
C1N51_RS18595	COG1388	LysM domain
C1N51_RS18595	COG1376	ErfK ybiS ycfS ynhG family protein
C1N51_RS18605	COG0513	Belongs to the DEAD box helicase family
C1N51_RS18610	COG1770	oligopeptidase
C1N51_RS18615	COG4771	TonB-dependent receptor
C1N51_RS18645	COG0573	inorganic phosphate transmembrane transporter activity
C1N51_RS18650	COG0581	inorganic phosphate transmembrane transporter activity
C1N51_RS18655	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C1N51_RS18690	COG0714	Associated with various cellular activities
C1N51_RS18720	COG2197	response regulator
C1N51_RS18745	COG0110	maltose O-acetyltransferase activity
C1N51_RS18755	COG4191	Histidine kinase
C1N51_RS18760	COG1028	Short-chain dehydrogenase reductase Sdr
C1N51_RS18810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C1N51_RS18815	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
C1N51_RS18825	COG1252	NADH dehydrogenase
C1N51_RS18830	COG1301	dicarboxylic acid transport
C1N51_RS18835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1N51_RS18880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N51_RS18880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N51_RS18880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N51_RS18885	COG2207	Transcriptional regulator
C1N51_RS18895	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N51_RS18900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N51_RS18905	COG0583	DNA-binding transcription factor activity
C1N51_RS18915	COG2084	Dehydrogenase
C1N51_RS18920	COG0753	catalase activity
C1N51_RS18930	COG2130	NADP-dependent
C1N51_RS18935	COG1309	transcriptional regulator
C1N51_RS18980	COG3206	protein involved in exopolysaccharide biosynthesis
C1N51_RS18980	COG0489	protein tyrosine kinase activity
C1N51_RS18995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C1N51_RS19000	COG2200	EAL domain
C1N51_RS19010	COG3842	ATPase activity
C1N51_RS19025	COG1175	transmembrane transport
C1N51_RS19030	COG3833	ABC-type maltose transport systems, permease component
C1N51_RS19060	COG2354	Protein conserved in bacteria
C1N51_RS19070	COG0401	homolog of Blt101
C1N51_RS19075	COG3217	Mosc domain protein beta barrel domain protein
C1N51_RS19075	COG0633	Ferredoxin
C1N51_RS19075	COG0633	Ferredoxin
C1N51_RS19075	COG3217	Mosc domain protein beta barrel domain protein
C1N51_RS19085	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C1N51_RS19125	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
C1N51_RS19130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N51_RS19140	COG0848	biopolymer transport protein
C1N51_RS19145	COG0811	peptide transport
C1N51_RS19150	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C1N51_RS19160	COG3721	Heme iron utilization protein
C1N51_RS19165	COG0748	coenzyme F420 binding
C1N51_RS19180	COG0784	Response regulator, receiver
C1N51_RS19180	COG0835	chemotaxis
C1N51_RS19185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1N51_RS19190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C1N51_RS19195	COG0366	Alpha amylase catalytic
C1N51_RS19235	COG0583	DNA-binding transcription factor activity
C1N51_RS19250	COG2249	NAD(P)H dehydrogenase (quinone) activity
C1N51_RS19255	COG0583	DNA-binding transcription factor activity
C1N51_RS19275	COG2814	Major facilitator Superfamily
C1N51_RS19285	COG4977	sequence-specific DNA binding
C1N51_RS19290	COG0673	inositol 2-dehydrogenase activity
C1N51_RS19295	COG2194	sulfuric ester hydrolase activity
C1N51_RS19300	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C1N51_RS19310	COG2205	protein histidine kinase activity
C1N51_RS19315	COG0745	RESPONSE REGULATOR receiver
C1N51_RS19325	COG3335	DDE superfamily endonuclease
C1N51_RS19345	COG4221	oxidoreductase activity
C1N51_RS19360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1N51_RS19380	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C1N51_RS19390	COG2814	Major facilitator Superfamily
C1N51_RS19405	COG1418	mRNA catabolic process
C1N51_RS19420	COG0402	S-adenosylhomocysteine deaminase activity
C1N51_RS19425	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C1N51_RS19430	COG2239	Acts as a magnesium transporter
C1N51_RS19435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C1N51_RS19440	COG1566	PFAM secretion protein HlyD family protein
C1N51_RS19465	COG0745	RESPONSE REGULATOR receiver
C1N51_RS19470	COG2205	protein histidine kinase activity
C1N51_RS19485	COG0531	amino acid
C1N51_RS19500	COG0583	DNA-binding transcription factor activity
C1N51_RS19525	COG5002	protein histidine kinase activity
C1N51_RS19525	COG2205	protein histidine kinase activity
C1N51_RS19525	COG0784	Response regulator, receiver
C1N51_RS19530	COG0673	inositol 2-dehydrogenase activity
C1N51_RS19610	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N51_RS19615	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N51_RS19625	COG1280	lysine exporter protein (LysE YggA)
C1N51_RS19635	COG0183	Belongs to the thiolase family
C1N51_RS19660	COG3005	denitrification pathway
C1N51_RS19680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1N51_RS19685	COG3850	Histidine kinase
C1N51_RS19690	COG2197	response regulator
C1N51_RS19710	COG2195	Cleaves the N-terminal amino acid of tripeptides
C1N51_RS19735	COG0840	transmembrane signaling receptor activity
C1N51_RS19745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1N51_RS19750	COG0545	Peptidyl-prolyl cis-trans isomerase
C1N51_RS19780	COG1278	Cold shock
C1N51_RS19785	COG3036	rescue of stalled ribosome
C1N51_RS19815	COG1136	(ABC) transporter
C1N51_RS19815	COG0577	efflux transmembrane transporter activity
C1N51_RS19830	COG0783	Belongs to the Dps family
C1N51_RS19840	COG1619	proteins homologs of microcin C7 resistance protein MccF
C1N51_RS19845	COG2133	pyrroloquinoline quinone binding
C1N51_RS19850	COG1454	alcohol dehydrogenase
C1N51_RS19855	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C1N51_RS19875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1N51_RS19885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1N51_RS19890	COG3186	Phenylalanine-4-hydroxylase
C1N51_RS19920	COG3530	Putative quorum-sensing-regulated virulence factor
C1N51_RS19955	COG0523	cobalamin synthesis protein
C1N51_RS19965	COG0513	Belongs to the DEAD box helicase family
C1N51_RS19990	COG2200	EAL domain
C1N51_RS19995	COG1119	ATPase activity
C1N51_RS20010	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C1N51_RS20025	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
C1N51_RS20030	COG0513	Belongs to the DEAD box helicase family
C1N51_RS20045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C1N51_RS20060	COG3278	Belongs to the heme-copper respiratory oxidase family
C1N51_RS20100	COG1024	Enoyl-CoA hydratase
C1N51_RS20105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C1N51_RS20110	COG1960	acyl-CoA dehydrogenase activity
C1N51_RS20120	COG0183	Belongs to the thiolase family
C1N51_RS20130	COG1960	acyl-CoA dehydrogenase activity
C1N51_RS20135	COG1024	Enoyl-CoA hydratase
C1N51_RS20140	COG1024	Enoyl-CoA hydratase
C1N51_RS20150	COG1028	Short-chain dehydrogenase reductase Sdr
C1N51_RS20155	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C1N51_RS20160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C1N51_RS20165	COG1845	cytochrome c oxidase, subunit III
C1N51_RS20170	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C1N51_RS20180	COG1902	pentaerythritol trinitrate reductase activity
C1N51_RS20180	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1N51_RS20195	COG1012	belongs to the aldehyde dehydrogenase family
C1N51_RS20205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1N51_RS20265	COG1126	abc transporter atp-binding protein
C1N51_RS20270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N51_RS20275	COG4215	(ABC) transporter
C1N51_RS20280	COG4160	amino acid transport
C1N51_RS20300	COG2200	EAL domain
C1N51_RS20345	COG0443	Heat shock 70 kDa protein
C1N51_RS20380	COG0745	RESPONSE REGULATOR receiver
C1N51_RS20395	COG1785	Belongs to the alkaline phosphatase family
C1N51_RS20425	COG0814	amino acid
C1N51_RS20430	COG5002	protein histidine kinase activity
C1N51_RS20430	COG5001	Diguanylate cyclase
C1N51_RS20440	COG0243	molybdopterin cofactor binding
C1N51_RS20460	COG3707	response regulator
C1N51_RS20470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C1N51_RS20470	COG1116	anion transmembrane transporter activity
C1N51_RS20475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N51_RS20480	COG1116	anion transmembrane transporter activity
C1N51_RS20485	COG2146	nitrite reductase [NAD(P)H] activity
C1N51_RS20485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1N51_RS20520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C1N51_RS20530	COG1902	pentaerythritol trinitrate reductase activity
C1N51_RS20540	COG0739	heme binding
C1N51_RS20650	COG2814	Major facilitator Superfamily
C1N51_RS20670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C1N51_RS20695	COG1132	(ABC) transporter
C1N51_RS20705	COG5640	endopeptidase activity
C1N51_RS20725	COG0583	DNA-binding transcription factor activity
C1N51_RS20745	COG3119	arylsulfatase activity
C1N51_RS20750	COG3119	arylsulfatase activity
C1N51_RS20755	COG0641	radical SAM
C1N51_RS20765	COG1733	regulation of RNA biosynthetic process
C1N51_RS20780	COG4977	sequence-specific DNA binding
C1N51_RS20875	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C1N51_RS20885	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C1N51_RS20895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N51_RS20900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N51_RS20915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N51_RS20915	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C1N51_RS20915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N51_RS20920	COG1105	Belongs to the carbohydrate kinase PfkB family
C1N51_RS20925	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N51_RS20925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N51_RS20930	COG1609	Transcriptional regulator
C1N51_RS20945	COG2200	EAL domain
C1N51_RS20945	COG2199	diguanylate cyclase activity
C1N51_RS20945	COG2203	Gaf domain
C1N51_RS20950	COG0765	amino acid transport
C1N51_RS20955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N51_RS20960	COG0765	amino acid transport
C1N51_RS20965	COG1126	abc transporter atp-binding protein
C1N51_RS20975	COG1979	alcohol dehydrogenase
C1N51_RS20980	COG2207	Transcriptional regulator
C1N51_RS20995	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1N51_RS21005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N51_RS21020	COG0784	Response regulator, receiver
C1N51_RS21020	COG3437	response regulator, receiver
C1N51_RS21025	COG0546	phosphoglycolate phosphatase activity
C1N51_RS21045	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
C1N51_RS21050	COG0513	Belongs to the DEAD box helicase family
C1N51_RS21055	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C1N51_RS21070	COG3038	cytochrome b561
C1N51_RS21080	COG2116	formate transmembrane transporter activity
C1N51_RS21090	COG0583	DNA-binding transcription factor activity
C1N51_RS21100	COG3593	DNA synthesis involved in DNA repair
C1N51_RS21105	COG0737	Belongs to the 5'-nucleotidase family
C1N51_RS21120	COG0646	methionine synthase
C1N51_RS21120	COG1410	methionine synthase
C1N51_RS21135	COG2267	carboxylic ester hydrolase activity
C1N51_RS21140	COG2067	long-chain fatty acid transport protein
C1N51_RS21150	COG0501	Belongs to the peptidase M48B family
C1N51_RS21155	COG2050	protein possibly involved in aromatic compounds catabolism
C1N51_RS21200	COG3300	MHYT domain
C1N51_RS21200	COG5001	Diguanylate cyclase
C1N51_RS21205	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C1N51_RS21215	COG4181	ATPase activity
C1N51_RS21220	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C1N51_RS21230	COG1984	allophanate hydrolase subunit 2
C1N51_RS21235	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C1N51_RS21245	COG5002	protein histidine kinase activity
C1N51_RS21245	COG5001	Diguanylate cyclase
C1N51_RS21245	COG3447	MASE1 domain protein
C1N51_RS21250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1N51_RS21265	COG0583	DNA-binding transcription factor activity
C1N51_RS21270	COG0045	succinate-CoA ligase (ADP-forming) activity
C1N51_RS21270	COG1042	CoA-binding domain protein
C1N51_RS21270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N51_RS21290	COG0023	Translation Initiation Factor
C1N51_RS21340	COG4128	Pfam Zonular occludens toxin
C1N51_RS21420	COG3140	Belongs to the UPF0181 family
C1N51_RS21440	COG2433	Pfam Transposase IS66
C1N51_RS21465	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C1N51_RS21470	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C1N51_RS21490	COG5001	Diguanylate cyclase
C1N51_RS21490	COG4251	negative regulation of phosphorylation
C1N51_RS21490	COG3706	GGDEF domain
C1N51_RS21490	COG2203	Gaf domain
C1N51_RS21500	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C1N51_RS21505	COG4149	molybdate abc transporter
C1N51_RS21510	COG0725	ABC transporter, periplasmic molybdate-binding protein
C1N51_RS21520	COG3111	PFAM Bacterial OB fold (BOF) protein
C1N51_RS21545	COG0534	Mate efflux family protein
C1N51_RS21550	COG0602	queuosine metabolic process
C1N51_RS21555	COG1328	CTP reductase activity
C1N51_RS21615	COG2197	response regulator
C1N51_RS21620	COG3851	Histidine kinase
C1N51_RS21625	COG2271	Major facilitator Superfamily
C1N51_RS21630	COG1482	cell wall glycoprotein biosynthetic process
C1N51_RS21665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1N51_RS21670	COG3118	belongs to the thioredoxin family
C1N51_RS21680	COG2205	protein histidine kinase activity
C1N51_RS21680	COG0745	RESPONSE REGULATOR receiver
C1N51_RS21680	COG3292	Two component regulator propeller
C1N51_RS21685	COG0534	Mate efflux family protein
C1N51_RS21705	COG0840	transmembrane signaling receptor activity
C1N51_RS21715	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C1N51_RS21735	COG2116	formate transmembrane transporter activity
C1N51_RS21745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1N51_RS21755	COG2199	diguanylate cyclase activity
C1N51_RS21840	COG0277	FAD linked oxidase domain protein
C1N51_RS21845	COG0583	DNA-binding transcription factor activity
C1N51_RS21850	COG1472	Belongs to the glycosyl hydrolase 3 family
C1N51_RS21865	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C1N51_RS21880	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C1N51_RS21890	COG1288	antiporter activity
C1N51_RS21900	COG2814	Major facilitator Superfamily
C1N51_RS21910	COG3040	lipid binding
C1N51_RS21940	COG3469	chitinase activity
C1N51_RS21950	COG0419	ATPase involved in DNA repair
C1N51_RS21955	COG0420	3'-5' exonuclease activity
C1N51_RS22035	COG0631	protein serine/threonine phosphatase activity
C1N51_RS22075	COG2815	serine threonine protein kinase
C1N51_RS22075	COG0515	serine threonine protein kinase
C1N51_RS22105	COG0346	lactoylglutathione lyase activity
C1N51_RS22110	COG1902	pentaerythritol trinitrate reductase activity
C1N51_RS22130	COG5642	Protein of unknown function (DUF2384)
C1N51_RS22145	COG1234	tRNA 3'-trailer cleavage
C1N51_RS22150	COG2067	long-chain fatty acid transport protein
C1N51_RS22200	COG0671	phosphoesterase, PA-phosphatase related
C1N51_RS22220	COG2962	Rard protein
C1N51_RS22230	COG2165	general secretion pathway protein
C1N51_RS22235	COG0784	Response regulator, receiver
C1N51_RS22235	COG0835	chemotaxis
C1N51_RS22240	COG0778	Nitroreductase
C1N51_RS22245	COG2197	response regulator
C1N51_RS22255	COG3706	GGDEF domain
C1N51_RS22260	COG2197	response regulator
C1N51_RS22265	COG5001	Diguanylate cyclase
C1N51_RS22265	COG1716	ATPase activity
C1N51_RS22270	COG0784	Response regulator, receiver
C1N51_RS22270	COG2205	protein histidine kinase activity
C1N51_RS22285	COG4771	TonB-dependent receptor
C1N51_RS22295	COG3335	DDE superfamily endonuclease
C1N51_RS22315	COG3335	DDE superfamily endonuclease
C1N51_RS22415	COG1522	sequence-specific DNA binding
C1N51_RS22450	COG0515	serine threonine protein kinase
C1N51_RS22475	COG3501	Rhs element vgr protein
C1N51_RS22490	COG2204	response regulator
C1N51_RS22515	COG0739	heme binding
C1N51_RS22520	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C1N51_RS22550	COG3069	C4-dicarboxylate transmembrane transporter activity
C1N51_RS22555	COG1704	LemA family
C1N51_RS22560	COG0501	Belongs to the peptidase M48B family
C1N51_RS22585	COG0641	radical SAM
C1N51_RS22605	COG3111	PFAM Bacterial OB fold (BOF) protein
C1N51_RS22610	COG1597	lipid kinase activity
C1N51_RS22615	COG0583	DNA-binding transcription factor activity
C1N51_RS22625	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C1N51_RS22635	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C1N51_RS22695	COG0714	Associated with various cellular activities
C1N51_RS22700	COG3063	Type IV pilus biogenesis stability protein PilW
C1N51_RS22705	COG3119	arylsulfatase activity
C1N51_RS22710	COG3119	arylsulfatase activity
C1N51_RS22725	COG2205	protein histidine kinase activity
C1N51_RS22725	COG2198	Histidine kinase
C1N51_RS22725	COG0784	Response regulator, receiver
C1N51_RS22730	COG1879	ABC-type sugar transport system periplasmic component
C1N51_RS22740	COG0210	DNA helicase
C1N51_RS22745	COG1289	transmembrane transporter activity
C1N51_RS22770	COG0789	Transcriptional regulator
C1N51_RS22775	COG4604	ABC transporter, ATP-binding protein
C1N51_RS22780	COG4605	iron ion homeostasis
C1N51_RS22785	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N51_RS22790	COG4607	ABC-type enterochelin transport system periplasmic component
C1N51_RS22805	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C1N51_RS22825	COG1609	Transcriptional regulator
C1N51_RS22830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N51_RS22835	COG1879	ABC-type sugar transport system periplasmic component
C1N51_RS22840	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1N51_RS22845	COG1129	ABC transporter
C1N51_RS22855	COG5001	Diguanylate cyclase
C1N51_RS22860	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C1N51_RS22865	COG1794	racemase activity, acting on amino acids and derivatives
C1N51_RS22870	COG1051	belongs to the nudix hydrolase family
C1N51_RS22895	COG0586	Pfam SNARE associated Golgi protein
C1N51_RS22940	COG0784	Response regulator, receiver
C1N51_RS22940	COG2205	protein histidine kinase activity
C1N51_RS22955	COG2203	Gaf domain
C1N51_RS22955	COG3706	GGDEF domain
C1N51_RS22955	COG4251	negative regulation of phosphorylation
C1N51_RS22955	COG5001	Diguanylate cyclase
C1N51_RS22975	COG2433	Pfam Transposase IS66
C1N51_RS22985	COG0330	HflC and HflK could
C1N51_RS22995	COG0517	IMP dehydrogenase activity
C1N51_RS22995	COG4175	Glycine betaine
C1N51_RS23000	COG4176	ABC-type proline glycine betaine transport system permease component
C1N51_RS23025	COG3706	GGDEF domain
C1N51_RS23030	COG3335	DDE superfamily endonuclease
C1N51_RS23040	COG0402	S-adenosylhomocysteine deaminase activity
C1N51_RS23100	COG0455	bacterial-type flagellum organization
C1N51_RS23110	COG4964	Belongs to the GSP D family
C1N51_RS23130	COG0583	DNA-binding transcription factor activity
C1N51_RS23155	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C1N51_RS23155	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C1N51_RS23170	COG4989	oxidoreductase activity
C1N51_RS23195	COG1914	H( )-stimulated, divalent metal cation uptake system
C1N51_RS23210	COG0303	'Molybdopterin
C1N51_RS23215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C1N51_RS23270	COG2897	thiosulfate sulfurtransferase activity
C1N51_RS23300	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C1N51_RS23310	COG2814	Major facilitator Superfamily
C1N51_RS23315	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1N51_RS23330	COG1612	heme a metabolic process
C1N51_RS23355	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
C1N51_RS23360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C1N51_RS23370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1N51_RS23380	COG1280	lysine exporter protein (LysE YggA)
C1N51_RS23405	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1N51_RS23420	COG0697	spore germination
C1N51_RS23440	COG2814	Major facilitator Superfamily
C1N51_RS23445	COG0583	DNA-binding transcription factor activity
C1N51_RS23450	COG5001	Diguanylate cyclase
C1N51_RS23455	COG0739	heme binding
C1N51_RS23480	COG3314	Sporulation integral membrane protein YlbJ
C1N51_RS23495	COG0814	amino acid
C1N51_RS23515	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C1N51_RS23520	COG1072	(Pantothenic acid kinase))
C1N51_RS23530	COG1063	alcohol dehydrogenase
C1N51_RS23535	COG2213	PTS system mannitol-specific
C1N51_RS23540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N51_RS23555	COG1733	regulation of RNA biosynthetic process
C1N51_RS23570	COG0798	PFAM Bile acid sodium symporter
C1N51_RS23585	COG1881	PFAM PEBP family protein
C1N51_RS23615	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
C1N51_RS23625	COG4145	pantothenate transmembrane transporter activity
C1N51_RS23630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N51_RS23635	COG0800	Aldolase
C1N51_RS23645	COG2706	6-phosphogluconolactonase activity
C1N51_RS23655	COG0840	transmembrane signaling receptor activity
C1N51_RS23665	COG1131	(ABC) transporter
C1N51_RS23670	COG0842	Transport permease protein
C1N51_RS23690	COG3383	formate dehydrogenase (NAD+) activity
C1N51_RS23715	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N51_RS23750	COG0456	acetyltransferase
C1N51_RS23760	COG0494	nUDIX hydrolase
C1N51_RS23775	COG1858	cytochrome C peroxidase
C1N51_RS23785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1N51_RS23795	COG2067	long-chain fatty acid transport protein
C1N51_RS23815	COG1505	serine-type exopeptidase activity
C1N51_RS23820	COG0488	(ABC) transporter
C1N51_RS23830	COG0589	response to stress
C1N51_RS23840	COG0584	glycerophosphoryl diester phosphodiesterase
C1N51_RS23850	COG1175	transmembrane transport
C1N51_RS23855	COG0395	ABC-type sugar transport system, permease component
C1N51_RS23860	COG3842	ATPase activity
C1N51_RS23885	COG0523	cobalamin synthesis protein
C1N51_RS23895	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C1N51_RS23905	COG4667	esterase of the alpha-beta hydrolase superfamily
C1N51_RS23910	COG1741	Belongs to the pirin family
C1N51_RS23915	COG1278	Cold shock
C1N51_RS23930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C1N51_RS23955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1N51_RS23965	COG1686	Belongs to the peptidase S11 family
C1N51_RS23970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1N51_RS23975	COG0625	glutathione transferase activity
C1N51_RS23985	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C1N51_RS24015	COG1028	Short-chain dehydrogenase reductase Sdr
C1N51_RS24040	COG3746	phosphate-selective porin O and P
C1N51_RS24060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N51_RS24110	COG0513	Belongs to the DEAD box helicase family
C1N51_RS24135	COG0583	DNA-binding transcription factor activity
C1N51_RS24155	COG1902	pentaerythritol trinitrate reductase activity
C1N51_RS24165	COG3853	Toxic anion resistance protein (TelA)
C1N51_RS24175	COG2255	four-way junction helicase activity
C1N51_RS24190	COG3122	Protein conserved in bacteria
C1N51_RS24195	COG2321	neutral zinc metallopeptidase
C1N51_RS24205	COG0583	DNA-binding transcription factor activity
C1N51_RS24210	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C1N51_RS24225	COG0252	asparaginase activity
C1N51_RS24235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1N51_RS24235	COG0574	Belongs to the PEP-utilizing enzyme family
C1N51_RS24245	COG2197	response regulator
C1N51_RS24250	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C1N51_RS24295	COG0583	DNA-binding transcription factor activity
C1N51_RS24300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1N51_RS24315	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C1N51_RS24320	COG0786	glutamate:sodium symporter activity
C1N51_RS24350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1N51_RS24355	COG0318	PFAM AMP-dependent synthetase and ligase
C1N51_RS24425	COG4964	Belongs to the GSP D family
C1N51_RS24475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N51_RS24490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N51_RS24500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1N51_RS24540	COG4948	Mandelate Racemase Muconate Lactonizing
C1N51_RS24570	COG1342	Belongs to the UPF0251 family
C1N51_RS24580	COG4176	ABC-type proline glycine betaine transport system permease component
C1N51_RS24585	COG4175	Glycine betaine
C1N51_RS24585	COG3448	diguanylate cyclase activity
C1N51_RS24605	COG0589	response to stress
C1N51_RS24610	COG0583	DNA-binding transcription factor activity
C1N51_RS24620	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C1N51_RS24655	COG1335	isochorismatase
C1N51_RS24670	COG0753	catalase activity
C1N51_RS24685	COG1349	DNA-binding transcription factor activity
C1N51_RS24690	COG0346	lactoylglutathione lyase activity
C1N51_RS24695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N51_RS24695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N51_RS24705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N51_RS24710	COG3537	Alpha-1,2-mannosidase
C1N51_RS24715	COG3537	Alpha-1,2-mannosidase
C1N51_RS24725	COG3537	Alpha-1,2-mannosidase
C1N51_RS24730	COG3537	Alpha-1,2-mannosidase
C1N51_RS24735	COG0737	Belongs to the 5'-nucleotidase family
C1N51_RS24765	COG1280	lysine exporter protein (LysE YggA)
C1N51_RS24770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N51_RS24780	COG0583	DNA-binding transcription factor activity
C1N51_RS24795	COG4628	conserved protein (DUF2132)
C1N51_RS24800	COG0488	(ABC) transporter
C1N51_RS24815	COG0346	lactoylglutathione lyase activity
C1N51_RS24820	COG0384	phenazine biosynthesis protein PhzF
C1N51_RS24835	COG3220	belongs to the UPF0276 family
C1N51_RS24850	COG1271	oxidase subunit
C1N51_RS24855	COG1294	oxidase, subunit
C1N51_RS24865	COG0251	oxidation-reduction process
C1N51_RS24905	COG1882	Formate acetyltransferase
C1N51_RS24910	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1N51_RS24915	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C1N51_RS24930	COG2205	protein histidine kinase activity
C1N51_RS24935	COG0745	RESPONSE REGULATOR receiver
C1N51_RS24945	COG0454	-acetyltransferase
C1N51_RS24955	COG2814	Major facilitator Superfamily
C1N51_RS24965	COG2988	succinylglutamate desuccinylase activity
C1N51_RS24980	COG3335	DDE superfamily endonuclease
C1N51_RS25010	COG0628	permease
C1N51_RS25015	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C1N51_RS25030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1N51_RS25040	COG4628	conserved protein (DUF2132)
C1N51_RS25045	COG0583	DNA-binding transcription factor activity
C1N51_RS25055	COG1686	Belongs to the peptidase S11 family
C1N51_RS25080	COG0415	Belongs to the DNA photolyase family
C1N51_RS25085	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
C1N51_RS25095	COG4667	esterase of the alpha-beta hydrolase superfamily
C1N51_RS25100	COG2095	MarC family integral membrane protein
C1N51_RS25115	COG1596	polysaccharide export
C1N51_RS25120	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N51_RS25160	COG1301	dicarboxylic acid transport
C1N51_RS25170	COG3339	Conserved Protein
C1N51_RS25175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N51_RS25180	COG0700	Nucleoside recognition
C1N51_RS25185	COG3366	ferrous iron transmembrane transporter activity
C1N51_RS25200	COG2433	Pfam Transposase IS66
C1N51_RS25215	COG0366	Alpha amylase catalytic
C1N51_RS25220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1N51_RS25225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C1N51_RS25230	COG1640	4-alpha-glucanotransferase
C1N51_RS25235	COG0058	SHG alpha-glucan phosphorylase activity
C1N51_RS25260	COG1999	signal sequence binding
C1N51_RS25275	COG1162	GTPase activity
C1N51_RS25280	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C1N51_RS25285	COG0673	inositol 2-dehydrogenase activity
C1N51_RS25310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N51_RS25315	COG0673	inositol 2-dehydrogenase activity
C1N51_RS25320	COG3962	Belongs to the TPP enzyme family
C1N51_RS25330	COG0477	Major facilitator Superfamily
C1N51_RS25330	COG2814	Major facilitator Superfamily
C1N51_RS25350	COG0183	Belongs to the thiolase family
C1N51_RS25355	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C1N51_RS25380	COG0531	amino acid
C1N51_RS25385	COG1982	Orn Lys Arg decarboxylase major
C1N51_RS25405	COG2356	endonuclease I
C1N51_RS25430	COG4580	involved in the transport of maltose and maltodextrins
C1N51_RS25440	COG2203	Gaf domain
C1N51_RS25440	COG2199	diguanylate cyclase activity
C1N51_RS25445	COG1648	precorrin-2 dehydrogenase activity
C1N51_RS25445	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C1N51_RS25465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C1N51_RS25475	COG1760	l-serine dehydratase
C1N51_RS25500	COG1609	Transcriptional regulator
C1N51_RS25510	COG2814	Major facilitator Superfamily
C1N51_RS25525	COG0739	heme binding
C1N51_RS25540	COG0800	Aldolase
C1N51_RS25545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N51_RS25550	COG1263	PTS System
C1N51_RS25550	COG2190	(PTS) system
C1N51_RS25550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N51_RS25560	COG2188	Transcriptional regulator
C1N51_RS25585	COG3121	Chaperone
C1N51_RS25590	COG3188	usher protein
C1N51_RS25615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N51_RS25615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N51_RS25615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N51_RS25625	COG0383	alpha-mannosidase activity
C1N51_RS25630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N51_RS25655	COG0612	Peptidase, M16
C1N51_RS25670	COG0826	peptidase U32
C1N51_RS25695	COG0463	Glycosyl transferase, family 2
C1N51_RS25710	COG1335	isochorismatase
C1N51_RS25715	COG1136	(ABC) transporter
C1N51_RS25720	COG0577	efflux transmembrane transporter activity
C1N51_RS25765	COG1764	response to oxidative stress
C1N51_RS25770	COG1846	Transcriptional regulator
C1N51_RS25780	COG3634	alkyl hydroperoxide reductase activity
C1N51_RS25810	COG2610	gluconate transmembrane transporter activity
C1N51_RS25815	COG3622	Belongs to the hyi family
C1N51_RS25820	COG0235	Class ii aldolase
C1N51_RS25825	COG3395	kinase activity
C1N51_RS25830	COG2084	Dehydrogenase
C1N51_RS25835	COG1349	DNA-binding transcription factor activity
C1N51_RS25850	COG0583	DNA-binding transcription factor activity
C1N51_RS25855	COG1486	melibiose metabolic process
C1N51_RS25870	COG1522	sequence-specific DNA binding
C1N51_RS25875	COG0544	peptidyl-prolyl cis-trans isomerase activity
C1N51_RS25890	COG2258	MOSC domain
C1N51_RS25900	COG1757	Na H antiporter
C1N51_RS25905	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C1N51_RS25940	COG1312	Catalyzes the dehydration of D-mannonate
C1N51_RS25945	COG2186	Transcriptional regulator
C1N51_RS25955	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1N51_RS25965	COG0246	Mannitol dehydrogenase
C1N51_RS25970	COG1904	glucuronate isomerase
C1N51_RS25975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N51_RS25980	COG0800	Aldolase
C1N51_RS26015	COG1132	(ABC) transporter
C1N51_RS26150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N51_RS26150	COG1263	PTS System
C1N51_RS26155	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C1N51_RS26180	COG1444	tRNA N-acetyltransferase activity
C1N51_RS26215	COG4608	Belongs to the ABC transporter superfamily
C1N51_RS26220	COG0444	Belongs to the ABC transporter superfamily
C1N51_RS26265	COG0772	Belongs to the SEDS family
C1N51_RS26280	COG1566	PFAM secretion protein HlyD family protein
C1N51_RS26285	COG0583	DNA-binding transcription factor activity
C1N51_RS26295	COG1136	(ABC) transporter
C1N51_RS26315	COG3275	phosphorelay sensor kinase activity
C1N51_RS26320	COG3279	Response regulator of the LytR AlgR family
C1N51_RS26330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C1N51_RS26350	COG0786	glutamate:sodium symporter activity
C1N51_RS26355	COG1028	Short-chain dehydrogenase reductase Sdr
C1N51_RS26390	COG1131	(ABC) transporter
C1N51_RS26395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N51_RS26400	COG0786	glutamate:sodium symporter activity
C1N51_RS26435	COG3335	DDE superfamily endonuclease
C1N51_RS26500	COG2259	Doxx family
C1N51_RS26510	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C1N51_RS26515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C1N51_RS26525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C1N51_RS26590	COG5001	Diguanylate cyclase
C1N51_RS26605	COG1609	Transcriptional regulator
C1N51_RS26620	COG0395	ABC-type sugar transport system, permease component
C1N51_RS26625	COG2723	6-phospho-beta-galactosidase activity
C1N51_RS26630	COG3842	ATPase activity
C1N51_RS26635	COG1609	Transcriptional regulator
C1N51_RS26645	COG0747	negative chemotaxis
C1N51_RS26655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N51_RS26660	COG0444	Belongs to the ABC transporter superfamily
C1N51_RS26665	COG4608	Belongs to the ABC transporter superfamily
C1N51_RS26675	COG1609	Transcriptional regulator
C1N51_RS26695	COG1472	Belongs to the glycosyl hydrolase 3 family
C1N51_RS26700	COG0534	Mate efflux family protein
C1N51_RS26705	COG0564	pseudouridine synthase activity
C1N51_RS26710	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C1N51_RS26720	COG0561	phosphatase activity
C1N51_RS26745	COG3152	Membrane
C1N51_RS26760	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C1N51_RS26780	COG0583	DNA-binding transcription factor activity
C1N51_RS26835	COG2076	Multidrug Resistance protein
C1N51_RS26850	COG1357	PFAM Pentapeptide repeats (8 copies)
C1N51_RS26855	COG3047	cAMP biosynthetic process
C1N51_RS26865	COG2814	Major facilitator Superfamily
C1N51_RS26885	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C1N51_RS26885	COG3408	Glycogen debranching enzyme
C1N51_RS26980	COG3835	regulator
C1N51_RS26985	COG1929	Belongs to the glycerate kinase type-1 family
C1N51_RS26990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N51_RS27030	COG0456	acetyltransferase
C1N51_RS27050	COG1028	Short-chain dehydrogenase reductase Sdr
C1N51_RS27060	COG3005	denitrification pathway
C1N51_RS27065	COG0243	molybdopterin cofactor binding
C1N51_RS27070	COG0671	phosphoesterase, PA-phosphatase related
C1N51_RS27085	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C1N51_RS27090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C1N51_RS27095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N51_RS27100	COG1116	anion transmembrane transporter activity
C1N51_RS27105	COG0351	phosphomethylpyrimidine kinase
C1N51_RS27110	COG0312	modulator of DNA gyrase
C1N51_RS27115	COG0312	modulator of DNA gyrase
C1N51_RS27180	COG3111	PFAM Bacterial OB fold (BOF) protein
C1N51_RS27190	COG3064	Membrane
C1N51_RS27265	COG2433	Pfam Transposase IS66
C1N51_RS27270	COG1253	flavin adenine dinucleotide binding
C1N51_RS27275	COG1253	flavin adenine dinucleotide binding
C1N51_RS27340	COG0776	regulation of translation
C1N51_RS27350	COG2433	Pfam Transposase IS66
C1N51_RS27475	COG2433	Pfam Transposase IS66
C1N51_RS27540	COG2885	chlorophyll binding
C1N51_RS27720	COG2433	Pfam Transposase IS66
C1N51_RS27755	COG4115	mRNA cleavage
C1N51_RS27760	COG2161	toxin-antitoxin pair type II binding
C1N51_RS27865	COG1484	DNA-dependent DNA replication
C1N51_RS27925	COG1192	Involved in chromosome partitioning
C1N51_RS27955	COG3609	addiction module antidote protein, CC2985 family
C1N51_RS28055	COG2433	Pfam Transposase IS66
C1N51_RS28175	COG3335	DDE superfamily endonuclease
C1N51_RS28195	COG2964	Protein conserved in bacteria
C1N51_RS28210	COG2801	Transposase and inactivated derivatives
C1N51_RS28340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C1N51_RS28405	COG2974	May be involved in recombination
C1N51_RS28475	COG3081	Nucleoid-associated protein
C1N51_RS28615	COG0305	Participates in initiation and elongation during chromosome replication
C1N51_RS28620	COG2337	Toxic component of a toxin-antitoxin (TA) module
C1N51_RS28770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1N51_RS28815	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
C1N51_RS28835	COG0741	lytic transglycosylase activity
C1N51_RS28950	COG3609	addiction module antidote protein, CC2985 family
C1N51_RS29040	COG3344	reverse transcriptase
C1N51_RS29085	COG0307	riboflavin synthase, alpha
C1N51_RS29235	COG1714	RDD family
C1N51_RS29245	COG3335	DDE superfamily endonuclease
C1N51_RS29395	COG0791	NLP P60 protein
C1N51_RS29400	COG1403	HNH endonuclease
C1N51_RS29405	COG2801	Transposase and inactivated derivatives
C1N51_RS29430	COG0384	phenazine biosynthesis protein PhzF
C1N51_RS29485	COG3335	DDE superfamily endonuclease
C1N51_RS29490	COG2433	Pfam Transposase IS66
C1N51_RS29515	COG0546	phosphoglycolate phosphatase activity
C1N51_RS29540	COG2801	Transposase and inactivated derivatives