locus-tag	class	description
CAY59_RS00005	COG2081	HI0933 family
CAY59_RS00035	COG2081	HI0933 family
CAY59_RS00045	COG1528	Iron-storage protein
CAY59_RS00050	COG0589	response to stress
CAY59_RS00070	COG5002	protein histidine kinase activity
CAY59_RS00070	COG5001	Diguanylate cyclase
CAY59_RS00075	COG1522	sequence-specific DNA binding
CAY59_RS00090	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CAY59_RS00100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAY59_RS00105	COG0800	Aldolase
CAY59_RS00110	COG2610	gluconate transmembrane transporter activity
CAY59_RS00115	COG3265	gluconokinase activity
CAY59_RS00120	COG0129	dihydroxy-acid dehydratase activity
CAY59_RS00130	COG2076	Multidrug Resistance protein
CAY59_RS00135	COG0583	DNA-binding transcription factor activity
CAY59_RS00140	COG1609	Transcriptional regulator
CAY59_RS00145	COG0515	serine threonine protein kinase
CAY59_RS00175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAY59_RS00180	COG0601	transmembrane transport
CAY59_RS00190	COG4172	Belongs to the ABC transporter superfamily
CAY59_RS00240	COG1309	transcriptional regulator
CAY59_RS00245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAY59_RS00250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAY59_RS00260	COG2960	long-chain fatty acid transporting porin activity
CAY59_RS00270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CAY59_RS00275	COG0583	DNA-binding transcription factor activity
CAY59_RS00330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CAY59_RS00335	COG1739	Uncharacterized protein family UPF0029
CAY59_RS00345	COG0183	Belongs to the thiolase family
CAY59_RS00350	COG0604	alcohol dehydrogenase
CAY59_RS00365	COG0425	Belongs to the sulfur carrier protein TusA family
CAY59_RS00375	COG2119	membrane
CAY59_RS00450	COG4964	Belongs to the GSP D family
CAY59_RS00470	COG3977	Valine--pyruvate aminotransferase
CAY59_RS00475	COG0071	Belongs to the small heat shock protein (HSP20) family
CAY59_RS00480	COG0187	DNA topoisomerase II activity
CAY59_RS00490	COG0592	DNA-directed DNA polymerase activity
CAY59_RS00515	COG1126	abc transporter atp-binding protein
CAY59_RS00545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CAY59_RS00565	COG1475	DNA binding
CAY59_RS00570	COG3312	ion transport
CAY59_RS00600	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CAY59_RS00610	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CAY59_RS00620	COG0765	amino acid transport
CAY59_RS00625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAY59_RS00630	COG2814	Major facilitator Superfamily
CAY59_RS00635	COG0583	DNA-binding transcription factor activity
CAY59_RS00640	COG3706	GGDEF domain
CAY59_RS00650	COG0129	dihydroxy-acid dehydratase activity
CAY59_RS00655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CAY59_RS00660	COG3978	acetolactate synthase activity
CAY59_RS00670	COG0606	chelatase, subunit chli
CAY59_RS00695	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CAY59_RS00700	COG0732	type I restriction modification DNA specificity domain
CAY59_RS00705	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CAY59_RS00740	COG0606	chelatase, subunit chli
CAY59_RS00745	COG2199	diguanylate cyclase activity
CAY59_RS00755	COG0204	Acyl-transferase
CAY59_RS00760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CAY59_RS00765	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CAY59_RS00775	COG3084	Protein conserved in bacteria
CAY59_RS00785	COG4326	sporulation control protein
CAY59_RS00790	COG1272	protein, Hemolysin III
CAY59_RS00800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CAY59_RS00805	COG0569	domain protein
CAY59_RS00810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CAY59_RS00810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CAY59_RS00820	COG0242	peptide deformylase activity
CAY59_RS00830	COG0758	DNA mediated transformation
CAY59_RS00840	COG0551	DNA topoisomerase type I activity
CAY59_RS00845	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CAY59_RS00850	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CAY59_RS00875	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CAY59_RS00925	COG2132	Multicopper oxidase
CAY59_RS00945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CAY59_RS00950	COG2104	thiamine diphosphate biosynthetic process
CAY59_RS00965	COG0006	proline dipeptidase activity
CAY59_RS00965	COG0006	proline dipeptidase activity
CAY59_RS00975	COG2814	Major facilitator Superfamily
CAY59_RS00995	COG3220	belongs to the UPF0276 family
CAY59_RS01005	COG0210	DNA helicase
CAY59_RS01010	COG0405	Gamma-glutamyltransferase
CAY59_RS01015	COG1280	lysine exporter protein (LysE YggA)
CAY59_RS01035	COG2962	Rard protein
CAY59_RS01040	COG0514	ATP-dependent DNA helicase (RecQ)
CAY59_RS01050	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CAY59_RS01065	COG3118	belongs to the thioredoxin family
CAY59_RS01080	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CAY59_RS01085	COG0633	Ferredoxin
CAY59_RS01125	COG3071	HemY protein
CAY59_RS01130	COG2959	enzyme of heme biosynthesis
CAY59_RS01135	COG1587	Uroporphyrinogen-III synthase
CAY59_RS01145	COG3072	Adenylate cyclase
CAY59_RS01150	COG1965	Belongs to the frataxin family
CAY59_RS01160	COG0019	diaminopimelate decarboxylase activity
CAY59_RS01180	COG1011	Hydrolase
CAY59_RS01185	COG3287	FIST C domain
CAY59_RS01185	COG2200	EAL domain
CAY59_RS01185	COG2199	diguanylate cyclase activity
CAY59_RS01190	COG3148	PFAM DTW domain containing protein
CAY59_RS01205	COG0561	phosphatase activity
CAY59_RS01210	COG2267	carboxylic ester hydrolase activity
CAY59_RS01215	COG1280	lysine exporter protein (LysE YggA)
CAY59_RS01220	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CAY59_RS01225	COG0640	Transcriptional regulator
CAY59_RS01230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CAY59_RS01285	COG2095	MarC family integral membrane protein
CAY59_RS01295	COG0742	ribosomal rna small subunit methyltransferase
CAY59_RS01300	COG0552	protein localization to endoplasmic reticulum
CAY59_RS01305	COG2884	Cell division ATP-binding protein ftsE
CAY59_RS01310	COG2177	Part of the ABC transporter FtsEX involved in
CAY59_RS01330	COG0705	Rhomboid family
CAY59_RS01335	COG1580	Controls the rotational direction of flagella during chemotaxis
CAY59_RS01340	COG3161	chorismate lyase activity
CAY59_RS01350	COG2937	Belongs to the GPAT DAPAT family
CAY59_RS01370	COG0534	Mate efflux family protein
CAY59_RS01375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAY59_RS01480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAY59_RS01490	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CAY59_RS01540	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CAY59_RS01545	COG0250	Participates in transcription elongation, termination and antitermination
CAY59_RS01560	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CAY59_RS01580	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CAY59_RS01585	COG2816	NAD+ diphosphatase activity
CAY59_RS01605	COG1573	uracil-dna glycosylase
CAY59_RS01615	COG3068	Protein conserved in bacteria
CAY59_RS01620	COG1253	flavin adenine dinucleotide binding
CAY59_RS01635	COG0151	Belongs to the GarS family
CAY59_RS01650	COG0789	Transcriptional regulator
CAY59_RS01655	COG3710	Transcriptional regulator
CAY59_RS01665	COG0531	amino acid
CAY59_RS01670	COG1982	Orn Lys Arg decarboxylase major
CAY59_RS01715	COG2199	diguanylate cyclase activity
CAY59_RS01720	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CAY59_RS01725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CAY59_RS01735	COG0439	Biotin carboxylase
CAY59_RS01740	COG0511	ligase activity, forming carbon-carbon bonds
CAY59_RS01745	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CAY59_RS01750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CAY59_RS01765	COG2814	Major facilitator Superfamily
CAY59_RS01770	COG0784	Response regulator, receiver
CAY59_RS01770	COG2198	Histidine kinase
CAY59_RS01770	COG2205	protein histidine kinase activity
CAY59_RS01790	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CAY59_RS01800	COG2095	MarC family integral membrane protein
CAY59_RS01815	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CAY59_RS01820	COG1027	Aspartate ammonia-lyase
CAY59_RS01825	COG3030	protein affecting phage T7 exclusion by the F plasmid
CAY59_RS01830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CAY59_RS01840	COG2205	protein histidine kinase activity
CAY59_RS01845	COG0745	RESPONSE REGULATOR receiver
CAY59_RS01865	COG0534	Mate efflux family protein
CAY59_RS01890	COG1509	lysine 2,3-aminomutase activity
CAY59_RS01920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CAY59_RS01925	COG1053	succinate dehydrogenase
CAY59_RS01950	COG4942	peptidase
CAY59_RS01955	COG1045	serine acetyltransferase
CAY59_RS01970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CAY59_RS01975	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CAY59_RS01985	COG0840	transmembrane signaling receptor activity
CAY59_RS02025	COG0471	metal ion transport
CAY59_RS02035	COG1162	GTPase activity
CAY59_RS02110	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CAY59_RS02115	COG0802	atpase or kinase
CAY59_RS02120	COG0860	N-Acetylmuramoyl-L-alanine amidase
CAY59_RS02125	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CAY59_RS02140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CAY59_RS02145	COG0330	HflC and HflK could
CAY59_RS02150	COG0330	HflC and HflK could
CAY59_RS02155	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CAY59_RS02160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CAY59_RS02170	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CAY59_RS02175	COG1017	nitric oxide dioxygenase activity
CAY59_RS02175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CAY59_RS02185	COG0557	exoribonuclease II activity
CAY59_RS02190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAY59_RS02195	COG0546	phosphoglycolate phosphatase activity
CAY59_RS02215	COG0512	Glutamine amidotransferase of anthranilate synthase
CAY59_RS02220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CAY59_RS02240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CAY59_RS02245	COG3954	Phosphoribulokinase
CAY59_RS02255	COG0429	hydrolase of the alpha beta-hydrolase fold
CAY59_RS02265	COG0488	(ABC) transporter
CAY59_RS02270	COG2249	NAD(P)H dehydrogenase (quinone) activity
CAY59_RS02285	COG1047	Peptidyl-prolyl cis-trans
CAY59_RS02295	COG1446	asparaginase
CAY59_RS02310	COG0545	Peptidyl-prolyl cis-trans isomerase
CAY59_RS02315	COG2964	Protein conserved in bacteria
CAY59_RS02320	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CAY59_RS02325	COG2923	Belongs to the DsrF TusC family
CAY59_RS02330	COG2168	tRNA wobble position uridine thiolation
CAY59_RS02345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CAY59_RS02355	COG2906	2 iron, 2 sulfur cluster binding
CAY59_RS02365	COG0281	malic enzyme
CAY59_RS02375	COG0626	cystathionine gamma-synthase activity
CAY59_RS02380	COG0527	aspartate kinase activity
CAY59_RS02380	COG0460	homoserine dehydrogenase
CAY59_RS02385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CAY59_RS02395	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CAY59_RS02405	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CAY59_RS02420	COG0165	Argininosuccinate lyase
CAY59_RS02420	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CAY59_RS02435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAY59_RS02440	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CAY59_RS02440	COG0678	peroxiredoxin activity
CAY59_RS02450	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CAY59_RS02495	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CAY59_RS02500	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CAY59_RS02510	COG2965	DNA replication, synthesis of RNA primer
CAY59_RS02530	COG0305	Participates in initiation and elongation during chromosome replication
CAY59_RS02535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CAY59_RS02545	COG0432	Pfam Uncharacterised protein family UPF0047
CAY59_RS02560	COG0735	belongs to the Fur family
CAY59_RS02565	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CAY59_RS02585	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CAY59_RS02665	COG0527	aspartate kinase activity
CAY59_RS02675	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CAY59_RS02685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CAY59_RS02700	COG0629	single-stranded DNA binding
CAY59_RS02705	COG2199	diguanylate cyclase activity
CAY59_RS02705	COG2200	EAL domain
CAY59_RS02730	COG3267	Type II secretory pathway component ExeA
CAY59_RS02730	COG3409	Peptidoglycan-binding domain 1 protein
CAY59_RS02740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CAY59_RS02745	COG1459	type II secretion system
CAY59_RS02755	COG2165	general secretion pathway protein
CAY59_RS02770	COG2165	general secretion pathway protein
CAY59_RS02790	COG1077	Cell shape determining protein MreB Mrl
CAY59_RS02795	COG1792	Involved in formation and maintenance of cell shape
CAY59_RS02800	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CAY59_RS02805	COG0424	maF-like protein
CAY59_RS02815	COG3164	Protein of unknown function
CAY59_RS02820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CAY59_RS02825	COG0312	modulator of DNA gyrase
CAY59_RS02830	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CAY59_RS02845	COG0564	pseudouridine synthase activity
CAY59_RS02850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAY59_RS02860	COG0312	modulator of DNA gyrase
CAY59_RS02865	COG2239	Acts as a magnesium transporter
CAY59_RS02870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAY59_RS02880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAY59_RS02885	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CAY59_RS02900	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CAY59_RS02910	COG0517	IMP dehydrogenase activity
CAY59_RS02910	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CAY59_RS02920	COG1127	ABC transporter
CAY59_RS02925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CAY59_RS02930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CAY59_RS02935	COG2854	intermembrane phospholipid transfer
CAY59_RS02945	COG5007	Belongs to the BolA IbaG family
CAY59_RS02955	COG0204	Acyl-transferase
CAY59_RS02960	COG0251	oxidation-reduction process
CAY59_RS03000	COG0456	acetyltransferase
CAY59_RS03010	COG0525	valine-tRNA ligase activity
CAY59_RS03015	COG2927	DNA polymerase III (CHI subunit)
CAY59_RS03025	COG0795	lipopolysaccharide-transporting ATPase activity
CAY59_RS03030	COG0795	lipopolysaccharide-transporting ATPase activity
CAY59_RS03040	COG1028	Short-chain dehydrogenase reductase Sdr
CAY59_RS03050	COG0726	polysaccharide deacetylase
CAY59_RS03055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CAY59_RS03065	COG1447	Phosphotransferase system cellobiose-specific component IIA
CAY59_RS03070	COG1486	melibiose metabolic process
CAY59_RS03080	COG1609	Transcriptional regulator
CAY59_RS03085	COG3437	response regulator, receiver
CAY59_RS03135	COG1012	belongs to the aldehyde dehydrogenase family
CAY59_RS03235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CAY59_RS03240	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CAY59_RS03255	COG0762	integral membrane protein
CAY59_RS03260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CAY59_RS03265	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CAY59_RS03280	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CAY59_RS03285	COG1678	Uncharacterized ACR, COG1678
CAY59_RS03290	COG0189	ligase activity
CAY59_RS03295	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CAY59_RS03300	COG2356	endonuclease I
CAY59_RS03320	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CAY59_RS03340	COG0191	fructose-bisphosphate aldolase activity
CAY59_RS03345	COG0668	transmembrane transport
CAY59_RS03360	COG0583	DNA-binding transcription factor activity
CAY59_RS03370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAY59_RS03380	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CAY59_RS03390	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CAY59_RS03400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAY59_RS03405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAY59_RS03425	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CAY59_RS03435	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CAY59_RS03440	COG1595	DNA-templated transcription, initiation
CAY59_RS03455	COG3086	response to oxidative stress
CAY59_RS03475	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CAY59_RS03480	COG1381	Involved in DNA repair and RecF pathway recombination
CAY59_RS03485	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CAY59_RS03510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CAY59_RS03515	COG3956	TIGRFAM MazG family protein
CAY59_RS03525	COG0148	phosphopyruvate hydratase activity
CAY59_RS03540	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CAY59_RS03570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CAY59_RS03580	COG1546	Belongs to the CinA family
CAY59_RS03585	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CAY59_RS03600	COG0527	aspartate kinase activity
CAY59_RS03660	COG3630	sodium ion export across plasma membrane
CAY59_RS03665	COG5016	pyruvate
CAY59_RS03665	COG0511	ligase activity, forming carbon-carbon bonds
CAY59_RS03670	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CAY59_RS03680	COG1238	metal cluster binding
CAY59_RS03685	COG0612	Peptidase, M16
CAY59_RS03705	COG4536	flavin adenine dinucleotide binding
CAY59_RS03710	COG4137	Cytochrome C assembly protein
CAY59_RS03715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CAY59_RS03740	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CAY59_RS03745	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CAY59_RS03750	COG0237	dephospho-CoA kinase activity
CAY59_RS03765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CAY59_RS03790	COG2186	Transcriptional regulator
CAY59_RS03795	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CAY59_RS03800	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAY59_RS03805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAY59_RS03820	COG0288	reversible hydration of carbon dioxide
CAY59_RS03825	COG0659	secondary active sulfate transmembrane transporter activity
CAY59_RS03830	COG1131	(ABC) transporter
CAY59_RS03835	COG0842	Transport permease protein
CAY59_RS03840	COG1560	Kdo2-lipid A biosynthetic process
CAY59_RS03855	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CAY59_RS03865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CAY59_RS03880	COG1643	Atp-dependent helicase
CAY59_RS03885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CAY59_RS03890	COG1752	Esterase of the alpha-beta hydrolase superfamily
CAY59_RS03895	COG1049	propionate catabolic process, 2-methylcitrate cycle
CAY59_RS03910	COG0004	ammonium transporteR
CAY59_RS03915	COG1840	ABC-type Fe3 transport system, periplasmic component
CAY59_RS03925	COG3842	ATPase activity
CAY59_RS03930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CAY59_RS03945	COG2971	BadF BadG BcrA BcrD
CAY59_RS03955	COG4608	Belongs to the ABC transporter superfamily
CAY59_RS03960	COG0444	Belongs to the ABC transporter superfamily
CAY59_RS03965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAY59_RS03975	COG0747	negative chemotaxis
CAY59_RS03995	COG0628	permease
CAY59_RS04020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAY59_RS04025	COG0739	heme binding
CAY59_RS04030	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CAY59_RS04040	COG2027	D-alanyl-D-alanine carboxypeptidase
CAY59_RS04045	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAY59_RS04050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CAY59_RS04055	COG1534	Rna-binding protein
CAY59_RS04065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CAY59_RS04070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CAY59_RS04085	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CAY59_RS04105	COG0195	Participates in both transcription termination and antitermination
CAY59_RS04125	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CAY59_RS04145	COG0534	Mate efflux family protein
CAY59_RS04150	COG0826	peptidase U32
CAY59_RS04155	COG0826	peptidase U32
CAY59_RS04165	COG3154	lipid carrier protein
CAY59_RS04170	COG3153	acetyltransferase
CAY59_RS04190	COG3706	GGDEF domain
CAY59_RS04200	COG0084	hydrolase, TatD family'
CAY59_RS04205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CAY59_RS04215	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CAY59_RS04225	COG0813	purine-nucleoside phosphorylase activity
CAY59_RS04235	COG0560	Phosphoserine phosphatase
CAY59_RS04245	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CAY59_RS04250	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CAY59_RS04280	COG1022	Amp-dependent synthetase and ligase
CAY59_RS04310	COG4964	Belongs to the GSP D family
CAY59_RS04370	COG0583	DNA-binding transcription factor activity
CAY59_RS04375	COG3408	Glycogen debranching enzyme
CAY59_RS04375	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CAY59_RS04385	COG0531	amino acid
CAY59_RS04390	COG2731	YhcH YjgK YiaL family protein
CAY59_RS04395	COG3250	beta-galactosidase activity
CAY59_RS04400	COG1609	Transcriptional regulator
CAY59_RS04405	COG0768	penicillin binding
CAY59_RS04410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CAY59_RS04415	COG1085	galactose-1-phosphate uridylyltransferase
CAY59_RS04425	COG2017	converts alpha-aldose to the beta-anomer
CAY59_RS04430	COG1609	Transcriptional regulator
CAY59_RS04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAY59_RS04435	COG1263	PTS System
CAY59_RS04445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CAY59_RS04470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CAY59_RS04475	COG1349	DNA-binding transcription factor activity
CAY59_RS04495	COG2271	Major facilitator Superfamily
CAY59_RS04500	COG0584	glycerophosphoryl diester phosphodiesterase
CAY59_RS04515	COG2171	N-acyltransferase activity
CAY59_RS04530	COG3141	response to X-ray
CAY59_RS04550	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CAY59_RS04555	COG1074	ATP-dependent DNA helicase activity
CAY59_RS04560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CAY59_RS04580	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CAY59_RS04580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CAY59_RS04595	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CAY59_RS04600	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CAY59_RS04605	COG2166	iron-sulfur cluster assembly
CAY59_RS04610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CAY59_RS04615	COG0693	protein deglycase activity
CAY59_RS04620	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CAY59_RS04625	COG3248	Nucleoside-binding outer membrane protein
CAY59_RS04645	COG1595	DNA-templated transcription, initiation
CAY59_RS04675	COG0271	Belongs to the BolA IbaG family
CAY59_RS04710	COG1477	protein flavinylation
CAY59_RS04730	COG0514	ATP-dependent DNA helicase (RecQ)
CAY59_RS04735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CAY59_RS04750	COG0733	neurotransmitter:sodium symporter activity
CAY59_RS04775	COG1720	tRNA m6t6A37 methyltransferase activity
CAY59_RS04790	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CAY59_RS04825	COG3098	single-species biofilm formation
CAY59_RS04830	COG0564	pseudouridine synthase activity
CAY59_RS04845	COG0024	Methionine aminopeptidase
CAY59_RS04870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CAY59_RS04875	COG0575	Belongs to the CDS family
CAY59_RS04885	COG0750	zinc metalloprotease
CAY59_RS04895	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CAY59_RS04900	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CAY59_RS04925	COG0587	DNA-directed DNA polymerase activity
CAY59_RS04945	COG0347	Belongs to the P(II) protein family
CAY59_RS04960	COG1388	LysM domain
CAY59_RS04960	COG0741	lytic transglycosylase activity
CAY59_RS04970	COG2226	methyltransferase
CAY59_RS04980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CAY59_RS05010	COG1960	acyl-CoA dehydrogenase activity
CAY59_RS05015	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CAY59_RS05020	COG0121	glutamine amidotransferase
CAY59_RS05025	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CAY59_RS05030	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CAY59_RS05035	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CAY59_RS05040	COG2233	PERMEase
CAY59_RS05060	COG1393	Belongs to the ArsC family
CAY59_RS05065	COG4783	chaperone-mediated protein folding
CAY59_RS05080	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CAY59_RS05085	COG2716	regulation of RNA biosynthetic process
CAY59_RS05090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAY59_RS05095	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CAY59_RS05115	COG1393	Belongs to the ArsC family
CAY59_RS05145	COG2837	iron assimilation
CAY59_RS05150	COG2169	Transcriptional regulator
CAY59_RS05155	COG1486	melibiose metabolic process
CAY59_RS05160	COG2211	Major facilitator Superfamily
CAY59_RS05170	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CAY59_RS05180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CAY59_RS05185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CAY59_RS05190	COG1334	flagellar protein FlaG
CAY59_RS05195	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CAY59_RS05205	COG1516	flagellar protein fliS
CAY59_RS05225	COG1677	Flagellar hook-basal body complex protein FliE
CAY59_RS05235	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CAY59_RS05290	COG1987	bacterial-type flagellum assembly
CAY59_RS05295	COG1684	flagellar biosynthetic protein fliR
CAY59_RS05330	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CAY59_RS05335	COG0643	Histidine kinase
CAY59_RS05335	COG0784	Response regulator, receiver
CAY59_RS05335	COG2198	Histidine kinase
CAY59_RS05340	COG2201	protein-glutamate methylesterase activity
CAY59_RS05345	COG1192	Involved in chromosome partitioning
CAY59_RS05355	COG0835	chemotaxis
CAY59_RS05365	COG4133	protoheme IX ABC transporter activity
CAY59_RS05370	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CAY59_RS05375	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CAY59_RS05390	COG1138	Cytochrome C-type biogenesis protein
CAY59_RS05395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAY59_RS05405	COG3088	subunit of a heme lyase
CAY59_RS05405	COG4235	cytochrome complex assembly
CAY59_RS05410	COG2853	Lipoprotein
CAY59_RS05415	COG2067	long-chain fatty acid transport protein
CAY59_RS05440	COG0183	Belongs to the thiolase family
CAY59_RS05460	COG2062	phosphohistidine phosphatase, SixA
CAY59_RS05470	COG2890	protein-(glutamine-N5) methyltransferase activity
CAY59_RS05480	COG2860	membrane
CAY59_RS05485	COG3101	peptidyl-lysine hydroxylation
CAY59_RS05510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CAY59_RS05520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAY59_RS05550	COG0285	dihydrofolate synthase activity
CAY59_RS05555	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CAY59_RS05560	COG1286	toxin biosynthetic process
CAY59_RS05565	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CAY59_RS05570	COG0583	DNA-binding transcription factor activity
CAY59_RS05585	COG2832	Protein of unknown function (DUF454)
CAY59_RS05595	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CAY59_RS05605	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CAY59_RS05610	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CAY59_RS05615	COG0814	amino acid
CAY59_RS05620	COG0251	oxidation-reduction process
CAY59_RS05630	COG2964	Protein conserved in bacteria
CAY59_RS05640	COG2983	Belongs to the UPF0260 family
CAY59_RS05645	COG2261	transglycosylase associated protein
CAY59_RS05650	COG2985	domain, Protein
CAY59_RS05655	COG0076	glutamate decarboxylase activity
CAY59_RS05660	COG0668	transmembrane transport
CAY59_RS05670	COG0346	lactoylglutathione lyase activity
CAY59_RS05680	COG1785	Belongs to the alkaline phosphatase family
CAY59_RS05700	COG2226	methyltransferase
CAY59_RS05720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CAY59_RS05735	COG3139	Protein of unknown function (DUF1315)
CAY59_RS05740	COG0252	asparaginase activity
CAY59_RS05745	COG0616	signal peptide processing
CAY59_RS05750	COG0446	pyridine nucleotide-disulphide oxidoreductase
CAY59_RS05750	COG1902	pentaerythritol trinitrate reductase activity
CAY59_RS05755	COG0778	Nitroreductase
CAY59_RS05760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CAY59_RS05775	COG0123	including yeast histone deacetylase and acetoin utilization protein
CAY59_RS05785	COG4269	membrane
CAY59_RS05800	COG3083	sulfuric ester hydrolase activity
CAY59_RS05825	COG1757	Na H antiporter
CAY59_RS05830	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CAY59_RS05835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CAY59_RS05840	COG2095	MarC family integral membrane protein
CAY59_RS05845	COG1012	belongs to the aldehyde dehydrogenase family
CAY59_RS05845	COG1454	alcohol dehydrogenase
CAY59_RS05850	COG1028	Short-chain dehydrogenase reductase Sdr
CAY59_RS05865	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CAY59_RS05875	COG2056	Na+-H+ antiporter family
CAY59_RS05885	COG2885	chlorophyll binding
CAY59_RS05895	COG0346	lactoylglutathione lyase activity
CAY59_RS05900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CAY59_RS05905	COG4660	Part of a membrane complex involved in electron transport
CAY59_RS05910	COG4659	FMN binding
CAY59_RS05915	COG4658	electron transport chain
CAY59_RS05930	COG4657	Part of a membrane complex involved in electron transport
CAY59_RS05935	COG1882	Formate acetyltransferase
CAY59_RS05945	COG0745	RESPONSE REGULATOR receiver
CAY59_RS05985	COG0556	nucleotide-excision repair
CAY59_RS06000	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CAY59_RS06005	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CAY59_RS06010	COG0521	Mo-molybdopterin cofactor biosynthetic process
CAY59_RS06020	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CAY59_RS06025	COG0314	molybdopterin synthase activity
CAY59_RS06035	COG0601	transmembrane transport
CAY59_RS06040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAY59_RS06045	COG0444	Belongs to the ABC transporter superfamily
CAY59_RS06055	COG0435	Glutathione S-transferase
CAY59_RS06060	COG3174	membrane
CAY59_RS06065	COG0857	belongs to the CobB CobQ family
CAY59_RS06065	COG0280	phosphate acetyltransferase
CAY59_RS06085	COG4120	Belongs to the binding-protein-dependent transport system permease family
CAY59_RS06090	COG1122	ATPase activity
CAY59_RS06095	COG0366	Alpha amylase catalytic
CAY59_RS06105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CAY59_RS06110	COG0653	protein targeting
CAY59_RS06115	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CAY59_RS06125	COG2186	Transcriptional regulator
CAY59_RS06155	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CAY59_RS06160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CAY59_RS06165	COG0659	secondary active sulfate transmembrane transporter activity
CAY59_RS06175	COG1530	ribonuclease E activity
CAY59_RS06180	COG0564	pseudouridine synthase activity
CAY59_RS06185	COG0424	maF-like protein
CAY59_RS06190	COG1399	metal-binding, possibly nucleic acid-binding protein
CAY59_RS06205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CAY59_RS06235	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CAY59_RS06250	COG0084	hydrolase, TatD family'
CAY59_RS06255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAY59_RS06255	COG1263	PTS System
CAY59_RS06270	COG0733	neurotransmitter:sodium symporter activity
CAY59_RS06285	COG4667	esterase of the alpha-beta hydrolase superfamily
CAY59_RS06310	COG2272	Belongs to the type-B carboxylesterase lipase family
CAY59_RS06320	COG3710	Transcriptional regulator
CAY59_RS06335	COG1940	carbohydrate kinase activity
CAY59_RS06340	COG0835	chemotaxis
CAY59_RS06340	COG0784	Response regulator, receiver
CAY59_RS06360	COG1028	Short-chain dehydrogenase reductase Sdr
CAY59_RS06365	COG0616	signal peptide processing
CAY59_RS06385	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CAY59_RS06390	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CAY59_RS06420	COG3009	Protein conserved in bacteria
CAY59_RS06425	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CAY59_RS06425	COG3008	intermembrane lipid transfer
CAY59_RS06430	COG2995	paraquat-inducible protein a
CAY59_RS06435	COG1609	Transcriptional regulator
CAY59_RS06450	COG4580	involved in the transport of maltose and maltodextrins
CAY59_RS06465	COG2211	Major facilitator Superfamily
CAY59_RS06470	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CAY59_RS06490	COG3118	belongs to the thioredoxin family
CAY59_RS06500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CAY59_RS06515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAY59_RS06535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAY59_RS06545	COG0577	efflux transmembrane transporter activity
CAY59_RS06555	COG1136	(ABC) transporter
CAY59_RS06555	COG0577	efflux transmembrane transporter activity
CAY59_RS06570	COG2176	DNA-directed DNA polymerase activity
CAY59_RS06660	COG3850	Histidine kinase
CAY59_RS06660	COG5002	protein histidine kinase activity
CAY59_RS06665	COG0745	RESPONSE REGULATOR receiver
CAY59_RS06670	COG0463	Glycosyl transferase, family 2
CAY59_RS06675	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CAY59_RS06685	COG0840	transmembrane signaling receptor activity
CAY59_RS06700	COG2175	clavaminate synthase activity
CAY59_RS06705	COG2964	Protein conserved in bacteria
CAY59_RS06710	COG0251	oxidation-reduction process
CAY59_RS06720	COG0446	pyridine nucleotide-disulphide oxidoreductase
CAY59_RS06745	COG1032	radical SAM domain protein
CAY59_RS06750	COG5001	Diguanylate cyclase
CAY59_RS06750	COG1716	ATPase activity
CAY59_RS06780	COG2350	Protein conserved in bacteria
CAY59_RS06810	COG1301	dicarboxylic acid transport
CAY59_RS06815	COG0159	tryptophan synthase activity
CAY59_RS06825	COG0135	phosphoribosylanthranilate isomerase activity
CAY59_RS06825	COG0134	indole-3-glycerol-phosphate synthase activity
CAY59_RS06835	COG0512	Glutamine amidotransferase of anthranilate synthase
CAY59_RS06840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CAY59_RS06850	COG0613	PHP domain protein
CAY59_RS06855	COG0009	L-threonylcarbamoyladenylate synthase
CAY59_RS06865	COG1187	pseudouridine synthase activity
CAY59_RS06885	COG0417	DNA replication proofreading
CAY59_RS06890	COG2197	response regulator
CAY59_RS06895	COG0322	excinuclease ABC activity
CAY59_RS06935	COG0019	diaminopimelate decarboxylase activity
CAY59_RS06950	COG1058	Belongs to the CinA family
CAY59_RS06950	COG1546	Belongs to the CinA family
CAY59_RS06960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CAY59_RS06965	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CAY59_RS06990	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CAY59_RS07000	COG0437	4 iron, 4 sulfur cluster binding
CAY59_RS07005	COG3301	Polysulphide reductase, NrfD
CAY59_RS07010	COG1138	Cytochrome C-type biogenesis protein
CAY59_RS07020	COG4235	cytochrome complex assembly
CAY59_RS07020	COG3088	subunit of a heme lyase
CAY59_RS07055	COG2989	Protein conserved in bacteria
CAY59_RS07060	COG3108	Peptidase M15
CAY59_RS07065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAY59_RS07080	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CAY59_RS07105	COG1846	Transcriptional regulator
CAY59_RS07110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CAY59_RS07115	COG0840	transmembrane signaling receptor activity
CAY59_RS07135	COG1448	Aminotransferase
CAY59_RS07140	COG2770	Histidine kinase
CAY59_RS07140	COG3437	response regulator, receiver
CAY59_RS07155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAY59_RS07180	COG0720	synthase
CAY59_RS07185	COG2197	response regulator
CAY59_RS07200	COG1760	l-serine dehydratase
CAY59_RS07205	COG0814	amino acid
CAY59_RS07220	COG0784	Response regulator, receiver
CAY59_RS07220	COG2205	protein histidine kinase activity
CAY59_RS07225	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CAY59_RS07240	COG3106	COG3106 Predicted ATPase
CAY59_RS07255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAY59_RS07485	COG0494	nUDIX hydrolase
CAY59_RS07950	COG4221	oxidoreductase activity
CAY59_RS07995	COG0456	acetyltransferase
CAY59_RS08000	COG0471	metal ion transport
CAY59_RS08005	COG4191	Histidine kinase
CAY59_RS08005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAY59_RS08025	COG1280	lysine exporter protein (LysE YggA)
CAY59_RS08030	COG1328	CTP reductase activity
CAY59_RS08035	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CAY59_RS08045	COG0861	Integral membrane protein TerC family
CAY59_RS08055	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CAY59_RS08060	COG4221	oxidoreductase activity
CAY59_RS08070	COG0814	amino acid
CAY59_RS08090	COG1132	(ABC) transporter
CAY59_RS08095	COG1132	(ABC) transporter
CAY59_RS08100	COG2165	general secretion pathway protein
CAY59_RS08105	COG0583	DNA-binding transcription factor activity
CAY59_RS08130	COG0443	Heat shock 70 kDa protein
CAY59_RS08135	COG0443	Heat shock 70 kDa protein
CAY59_RS08145	COG3706	GGDEF domain
CAY59_RS08175	COG3227	Zinc metalloprotease (Elastase)
CAY59_RS08195	COG3842	ATPase activity
CAY59_RS08200	COG3459	Glycosyltransferase 36 associated
CAY59_RS08210	COG1653	transport
CAY59_RS08220	COG0395	ABC-type sugar transport system, permease component
CAY59_RS08235	COG0243	molybdopterin cofactor binding
CAY59_RS08240	COG0437	4 iron, 4 sulfur cluster binding
CAY59_RS08245	COG3302	dmso reductase anchor subunit
CAY59_RS08260	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CAY59_RS08265	COG1643	Atp-dependent helicase
CAY59_RS08290	COG3063	Type IV pilus biogenesis stability protein PilW
CAY59_RS08320	COG0531	amino acid
CAY59_RS08325	COG1280	lysine exporter protein (LysE YggA)
CAY59_RS08330	COG1560	Kdo2-lipid A biosynthetic process
CAY59_RS08350	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CAY59_RS08355	COG1280	lysine exporter protein (LysE YggA)
CAY59_RS08390	COG1115	amino acid carrier protein
CAY59_RS08415	COG1368	sulfuric ester hydrolase activity
CAY59_RS08420	COG0215	cysteine-tRNA ligase activity
CAY59_RS08425	COG0534	Mate efflux family protein
CAY59_RS08430	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CAY59_RS08440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CAY59_RS08445	COG0456	acetyltransferase
CAY59_RS08450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CAY59_RS08455	COG0662	Cupin 2, conserved barrel domain protein
CAY59_RS08460	COG0527	aspartate kinase activity
CAY59_RS08475	COG1858	cytochrome C peroxidase
CAY59_RS08480	COG1404	Belongs to the peptidase S8 family
CAY59_RS08485	COG3227	Zinc metalloprotease (Elastase)
CAY59_RS08500	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CAY59_RS08505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CAY59_RS08510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAY59_RS08535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CAY59_RS08540	COG0667	Aldo Keto reductase
CAY59_RS08555	COG0583	DNA-binding transcription factor activity
CAY59_RS08560	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAY59_RS08565	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CAY59_RS08570	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAY59_RS08575	COG0679	Auxin Efflux Carrier
CAY59_RS08615	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CAY59_RS08635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAY59_RS08640	COG1999	signal sequence binding
CAY59_RS08655	COG3005	denitrification pathway
CAY59_RS08670	COG0583	DNA-binding transcription factor activity
CAY59_RS08685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAY59_RS08705	COG3290	protein histidine kinase activity
CAY59_RS08710	COG4565	transcriptional regulatory protein
CAY59_RS08715	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CAY59_RS08720	COG0363	glucosamine-6-phosphate deaminase activity
CAY59_RS08725	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CAY59_RS08755	COG3284	Transcriptional regulator
CAY59_RS08760	COG1012	belongs to the aldehyde dehydrogenase family
CAY59_RS08765	COG2358	TRAP transporter, solute receptor (TAXI family
CAY59_RS08770	COG0730	response to heat
CAY59_RS08810	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CAY59_RS08815	COG0784	Response regulator, receiver
CAY59_RS08815	COG3437	response regulator, receiver
CAY59_RS08925	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CAY59_RS08930	COG0372	Belongs to the citrate synthase family
CAY59_RS08940	COG2828	Protein conserved in bacteria
CAY59_RS08955	COG3119	arylsulfatase activity
CAY59_RS08975	COG0561	phosphatase activity
CAY59_RS08980	COG0602	queuosine metabolic process
CAY59_RS08990	COG3706	GGDEF domain
CAY59_RS09055	COG0840	transmembrane signaling receptor activity
CAY59_RS09060	COG1254	Belongs to the acylphosphatase family
CAY59_RS09065	COG2920	part of a sulfur-relay system
CAY59_RS09075	COG0670	Belongs to the BI1 family
CAY59_RS09080	COG1126	abc transporter atp-binding protein
CAY59_RS09085	COG0765	amino acid transport
CAY59_RS09090	COG4597	amino acid ABC transporter
CAY59_RS09095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAY59_RS09110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CAY59_RS09135	COG3008	intermembrane lipid transfer
CAY59_RS09140	COG2995	paraquat-inducible protein a
CAY59_RS09145	COG1132	(ABC) transporter
CAY59_RS09150	COG1956	GAF domain-containing protein
CAY59_RS09155	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CAY59_RS09170	COG0308	aminopeptidase N
CAY59_RS09180	COG2902	Dehydrogenase
CAY59_RS09205	COG0488	(ABC) transporter
CAY59_RS09225	COG1067	ATP-dependent peptidase activity
CAY59_RS09255	COG0784	Response regulator, receiver
CAY59_RS09255	COG2205	protein histidine kinase activity
CAY59_RS09270	COG3278	Belongs to the heme-copper respiratory oxidase family
CAY59_RS09285	COG2010	Cytochrome c
CAY59_RS09295	COG2217	Heavy metal translocating P-type atpase
CAY59_RS09310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CAY59_RS09315	COG0589	response to stress
CAY59_RS09340	COG3842	ATPase activity
CAY59_RS09350	COG1177	transmembrane transport
CAY59_RS09360	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CAY59_RS09365	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CAY59_RS09385	COG0437	4 iron, 4 sulfur cluster binding
CAY59_RS09390	COG0243	molybdopterin cofactor binding
CAY59_RS09390	COG3383	formate dehydrogenase (NAD+) activity
CAY59_RS09400	COG3381	protein complex oligomerization
CAY59_RS09420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CAY59_RS09430	COG0584	glycerophosphoryl diester phosphodiesterase
CAY59_RS09435	COG0488	(ABC) transporter
CAY59_RS09450	COG4191	Histidine kinase
CAY59_RS09455	COG2204	response regulator
CAY59_RS09465	COG4662	Binding-protein-dependent transport system inner membrane component
CAY59_RS09470	COG3842	ATPase activity
CAY59_RS09480	COG0303	'Molybdopterin
CAY59_RS09490	COG1940	carbohydrate kinase activity
CAY59_RS09495	COG3148	PFAM DTW domain containing protein
CAY59_RS09545	COG0840	transmembrane signaling receptor activity
CAY59_RS09550	COG0791	NLP P60 protein
CAY59_RS09560	COG3706	GGDEF domain
CAY59_RS09565	COG2201	protein-glutamate methylesterase activity
CAY59_RS09570	COG3001	Fructosamine kinase
CAY59_RS09585	COG0534	Mate efflux family protein
CAY59_RS09595	COG1793	dna ligase
CAY59_RS09605	COG2885	chlorophyll binding
CAY59_RS09625	COG2204	response regulator
CAY59_RS09630	COG0438	transferase activity, transferring glycosyl groups
CAY59_RS09635	COG0438	transferase activity, transferring glycosyl groups
CAY59_RS09665	COG0438	transferase activity, transferring glycosyl groups
CAY59_RS09670	COG1215	transferase activity, transferring glycosyl groups
CAY59_RS09675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CAY59_RS09685	COG3064	Membrane
CAY59_RS09710	COG5001	Diguanylate cyclase
CAY59_RS09710	COG3300	MHYT domain
CAY59_RS09735	COG0110	maltose O-acetyltransferase activity
CAY59_RS09760	COG1846	Transcriptional regulator
CAY59_RS09770	COG1482	cell wall glycoprotein biosynthetic process
CAY59_RS09785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAY59_RS09805	COG0383	alpha-mannosidase activity
CAY59_RS09815	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CAY59_RS09840	COG3247	response to pH
CAY59_RS09845	COG0668	transmembrane transport
CAY59_RS09855	COG1404	Belongs to the peptidase S8 family
CAY59_RS09865	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CAY59_RS09900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAY59_RS09915	COG0786	glutamate:sodium symporter activity
CAY59_RS09940	COG0625	glutathione transferase activity
CAY59_RS09950	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CAY59_RS09965	COG2195	Cleaves the N-terminal amino acid of tripeptides
CAY59_RS10000	COG0813	purine-nucleoside phosphorylase activity
CAY59_RS10025	COG1451	nucleotide metabolic process
CAY59_RS10035	COG4932	domain protein
CAY59_RS10035	COG5492	domain, Protein
CAY59_RS10050	COG0745	RESPONSE REGULATOR receiver
CAY59_RS10060	COG0784	Response regulator, receiver
CAY59_RS10060	COG2205	protein histidine kinase activity
CAY59_RS10120	COG2165	general secretion pathway protein
CAY59_RS10145	COG0583	DNA-binding transcription factor activity
CAY59_RS10175	COG4139	cobalamin transport
CAY59_RS10190	COG2062	phosphohistidine phosphatase, SixA
CAY59_RS10200	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CAY59_RS10210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CAY59_RS10220	COG0702	epimerase
CAY59_RS10225	COG1823	symporter activity
CAY59_RS10235	COG2925	Exonuclease
CAY59_RS10245	COG1346	cytolysis
CAY59_RS10295	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAY59_RS10305	COG4607	ABC-type enterochelin transport system periplasmic component
CAY59_RS10310	COG4774	siderophore transport
CAY59_RS10330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAY59_RS10345	COG1132	(ABC) transporter
CAY59_RS10350	COG1535	isochorismatase
CAY59_RS10350	COG3433	isochorismatase activity
CAY59_RS10355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CAY59_RS10355	COG0072	phenylalanine-tRNA ligase activity
CAY59_RS10410	COG0251	oxidation-reduction process
CAY59_RS10455	COG2188	Transcriptional regulator
CAY59_RS10465	COG0010	Belongs to the arginase family
CAY59_RS10475	COG2986	histidine ammonia-lyase
CAY59_RS10520	COG0277	FAD linked oxidase domain protein
CAY59_RS10520	COG0247	lactate metabolic process
CAY59_RS10580	COG1643	Atp-dependent helicase
CAY59_RS10590	COG2949	membrane
CAY59_RS10595	COG0471	metal ion transport
CAY59_RS10600	COG3706	GGDEF domain
CAY59_RS10630	COG0492	ferredoxin-NADP+ reductase activity
CAY59_RS10635	COG4988	ABC transporter
CAY59_RS10640	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CAY59_RS10650	COG2610	gluconate transmembrane transporter activity
CAY59_RS10655	COG0583	DNA-binding transcription factor activity
CAY59_RS10660	COG2200	EAL domain
CAY59_RS10695	COG5001	Diguanylate cyclase
CAY59_RS10710	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CAY59_RS10720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAY59_RS10720	COG4191	Histidine kinase
CAY59_RS10735	COG3070	regulator of competence-specific genes
CAY59_RS10750	COG2431	L-lysine efflux transmembrane transporter activity
CAY59_RS10760	COG0076	glutamate decarboxylase activity
CAY59_RS10765	COG1737	Transcriptional regulator
CAY59_RS10775	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CAY59_RS10785	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CAY59_RS10815	COG4181	ATPase activity
CAY59_RS10820	COG0534	Mate efflux family protein
CAY59_RS10825	COG0702	epimerase
CAY59_RS10830	COG4667	esterase of the alpha-beta hydrolase superfamily
CAY59_RS10840	COG2814	Major facilitator Superfamily
CAY59_RS10845	COG1187	pseudouridine synthase activity
CAY59_RS10850	COG1061	Type III restriction enzyme res subunit
CAY59_RS10855	COG3706	GGDEF domain
CAY59_RS10925	COG3313	Fe-S protein
CAY59_RS10935	COG0659	secondary active sulfate transmembrane transporter activity
CAY59_RS10960	COG0493	'glutamate synthase
CAY59_RS10970	COG0398	Pfam SNARE associated Golgi protein
CAY59_RS10975	COG4134	Bacterial extracellular solute-binding protein
CAY59_RS10980	COG4135	transport system, permease component
CAY59_RS10985	COG4136	ATPase activity
CAY59_RS10990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CAY59_RS11005	COG3604	Transcriptional regulator
CAY59_RS11010	COG1151	hydroxylamine reductase activity
CAY59_RS11015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CAY59_RS11025	COG0564	pseudouridine synthase activity
CAY59_RS11035	COG0733	neurotransmitter:sodium symporter activity
CAY59_RS11045	COG0626	cystathionine gamma-synthase activity
CAY59_RS11050	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CAY59_RS11070	COG2818	Glycosylase
CAY59_RS11090	COG1983	PspC domain protein
CAY59_RS11100	COG1842	Phage shock protein A
CAY59_RS11105	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CAY59_RS11115	COG4168	peptide transport system, permease
CAY59_RS11120	COG4171	peptide transport system, permease
CAY59_RS11130	COG4172	Belongs to the ABC transporter superfamily
CAY59_RS11140	COG1227	inorganic diphosphatase activity
CAY59_RS11160	COG3005	denitrification pathway
CAY59_RS11165	COG4459	periplasmic nitrate reductase
CAY59_RS11170	COG0390	transport system, permease component
CAY59_RS11180	COG2116	formate transmembrane transporter activity
CAY59_RS11205	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CAY59_RS11210	COG1435	thymidine kinase activity
CAY59_RS11215	COG0215	cysteine-tRNA ligase activity
CAY59_RS11220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CAY59_RS11225	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CAY59_RS11230	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CAY59_RS11235	COG3012	SEC-C Motif Domain Protein
CAY59_RS11240	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CAY59_RS11240	COG0140	phosphoribosyl-ATP diphosphatase activity
CAY59_RS11250	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CAY59_RS11255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CAY59_RS11260	COG0131	Imidazoleglycerol-phosphate dehydratase
CAY59_RS11260	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CAY59_RS11270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CAY59_RS11285	COG1757	Na H antiporter
CAY59_RS11295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAY59_RS11305	COG0482	sulfurtransferase activity
CAY59_RS11315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CAY59_RS11335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CAY59_RS11350	COG0300	oxidoreductase activity
CAY59_RS11395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CAY59_RS11415	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CAY59_RS11435	COG0686	Belongs to the AlaDH PNT family
CAY59_RS11445	COG0583	DNA-binding transcription factor activity
CAY59_RS11470	COG0402	S-adenosylhomocysteine deaminase activity
CAY59_RS11495	COG3568	Endonuclease Exonuclease Phosphatase
CAY59_RS11515	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CAY59_RS11530	COG1288	antiporter activity
CAY59_RS11540	COG2186	Transcriptional regulator
CAY59_RS11550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAY59_RS11555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAY59_RS11585	COG0747	negative chemotaxis
CAY59_RS11590	COG4608	Belongs to the ABC transporter superfamily
CAY59_RS11595	COG0444	Belongs to the ABC transporter superfamily
CAY59_RS11605	COG2824	Alkylphosphonate utilization operon protein PhnA
CAY59_RS11625	COG3119	arylsulfatase activity
CAY59_RS11665	COG0457	Tetratricopeptide repeat
CAY59_RS11735	COG4790	Type iii secretion
CAY59_RS11740	COG4794	Type iii secretion
CAY59_RS11745	COG4791	protein targeting
CAY59_RS11750	COG4792	protein secretion
CAY59_RS11765	COG3177	Filamentation induced by cAMP protein fic
CAY59_RS11795	COG4669	(LipO)protein
CAY59_RS11890	COG2205	protein histidine kinase activity
CAY59_RS11890	COG0784	Response regulator, receiver
CAY59_RS11900	COG0754	glutathionylspermidine amidase activity
CAY59_RS11910	COG3766	membrane
CAY59_RS11925	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CAY59_RS11935	COG0823	Involved in the tonB-independent uptake of proteins
CAY59_RS11950	COG0811	peptide transport
CAY59_RS11965	COG4890	Cyd operon protein YbgT
CAY59_RS11970	COG1294	oxidase, subunit
CAY59_RS11975	COG1271	oxidase subunit
CAY59_RS11985	COG0632	four-way junction helicase activity
CAY59_RS11990	COG0840	transmembrane signaling receptor activity
CAY59_RS12005	COG1801	Protein of unknown function DUF72
CAY59_RS12025	COG0189	ligase activity
CAY59_RS12025	COG4067	protein conserved in archaea
CAY59_RS12050	COG0318	PFAM AMP-dependent synthetase and ligase
CAY59_RS12065	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CAY59_RS12070	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CAY59_RS12080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CAY59_RS12085	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CAY59_RS12090	COG0745	RESPONSE REGULATOR receiver
CAY59_RS12105	COG3070	regulator of competence-specific genes
CAY59_RS12125	COG0297	glycogen (starch) synthase activity
CAY59_RS12130	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CAY59_RS12135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CAY59_RS12165	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CAY59_RS12170	COG0542	response to heat
CAY59_RS12180	COG1278	Cold shock
CAY59_RS12190	COG1187	pseudouridine synthase activity
CAY59_RS12195	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CAY59_RS12210	COG0730	response to heat
CAY59_RS12215	COG3923	Primosomal replication protein n
CAY59_RS12225	COG0708	Exodeoxyribonuclease III
CAY59_RS12265	COG1882	Formate acetyltransferase
CAY59_RS12275	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CAY59_RS12290	COG2766	serine protein kinase
CAY59_RS12295	COG2718	Belongs to the UPF0229 family
CAY59_RS12300	COG2719	SpoVR family
CAY59_RS12320	COG1132	(ABC) transporter
CAY59_RS12325	COG0658	competence protein
CAY59_RS12325	COG2333	competence protein COMEC
CAY59_RS12335	COG4591	ABC-type transport system involved in lipoprotein release permease component
CAY59_RS12340	COG1136	(ABC) transporter
CAY59_RS12345	COG4591	ABC-type transport system involved in lipoprotein release permease component
CAY59_RS12355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CAY59_RS12370	COG1252	NADH dehydrogenase
CAY59_RS12400	COG0537	adenosine 5'-monophosphoramidase activity
CAY59_RS12420	COG2217	Heavy metal translocating P-type atpase
CAY59_RS12430	COG0516	GMP reductase activity
CAY59_RS12430	COG0517	IMP dehydrogenase activity
CAY59_RS12435	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CAY59_RS12440	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CAY59_RS12445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAY59_RS12455	COG3706	GGDEF domain
CAY59_RS12470	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CAY59_RS12475	COG1946	Acyl-CoA thioesterase
CAY59_RS12480	COG1522	sequence-specific DNA binding
CAY59_RS12505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAY59_RS12560	COG2855	membrane
CAY59_RS12580	COG0583	DNA-binding transcription factor activity
CAY59_RS12585	COG1263	PTS System
CAY59_RS12585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAY59_RS12585	COG2190	(PTS) system
CAY59_RS12600	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CAY59_RS12605	COG0596	Alpha beta hydrolase
CAY59_RS12615	COG1169	isochorismate synthase
CAY59_RS12620	COG0436	Aminotransferase
CAY59_RS12625	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CAY59_RS12645	COG1555	photosystem II stabilization
CAY59_RS12650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAY59_RS12655	COG0776	regulation of translation
CAY59_RS12660	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CAY59_RS12695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAY59_RS12700	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CAY59_RS12705	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAY59_RS12725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CAY59_RS12730	COG0569	domain protein
CAY59_RS12735	COG0513	Belongs to the DEAD box helicase family
CAY59_RS12740	COG1253	flavin adenine dinucleotide binding
CAY59_RS12760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAY59_RS12760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAY59_RS12765	COG3433	isochorismatase activity
CAY59_RS12765	COG1535	isochorismatase
CAY59_RS12770	COG1021	2,3-dihydroxybenzoate-AMP ligase
CAY59_RS12775	COG1169	isochorismate synthase
CAY59_RS12785	COG1028	Short-chain dehydrogenase reductase Sdr
CAY59_RS12815	COG2852	Protein conserved in bacteria
CAY59_RS12820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CAY59_RS12830	COG2951	lytic endotransglycosylase activity
CAY59_RS12845	COG2894	cell division
CAY59_RS12850	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CAY59_RS12855	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CAY59_RS12860	COG0318	PFAM AMP-dependent synthetase and ligase
CAY59_RS12865	COG2267	carboxylic ester hydrolase activity
CAY59_RS12870	COG3065	identical protein binding
CAY59_RS12880	COG1214	PFAM Peptidase M22, glycoprotease
CAY59_RS12885	COG1199	ATP-dependent helicase activity
CAY59_RS12910	COG3102	Protein conserved in bacteria
CAY59_RS12940	COG1918	ferrous iron import across plasma membrane
CAY59_RS12945	COG4977	sequence-specific DNA binding
CAY59_RS12950	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CAY59_RS12955	COG1121	(ABC) transporter
CAY59_RS12960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CAY59_RS12975	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAY59_RS12980	COG0567	Dehydrogenase, E1 component
CAY59_RS12990	COG1053	succinate dehydrogenase
CAY59_RS12995	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CAY59_RS13010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CAY59_RS13025	COG0033	Phosphoglucomutase
CAY59_RS13030	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CAY59_RS13035	COG0596	Alpha beta hydrolase
CAY59_RS13055	COG0735	belongs to the Fur family
CAY59_RS13065	COG2190	(PTS) system
CAY59_RS13065	COG1263	PTS System
CAY59_RS13065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAY59_RS13075	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CAY59_RS13080	COG1940	carbohydrate kinase activity
CAY59_RS13080	COG1846	Transcriptional regulator
CAY59_RS13085	COG4651	solute:proton antiporter activity
CAY59_RS13085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CAY59_RS13090	COG0367	asparagine synthase
CAY59_RS13100	COG3104	oligopeptide transport
CAY59_RS13105	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CAY59_RS13120	COG3710	Transcriptional regulator
CAY59_RS13140	COG0622	Phosphoesterase
CAY59_RS13170	COG1090	epimerase
CAY59_RS13175	COG0300	oxidoreductase activity
CAY59_RS13185	COG3118	belongs to the thioredoxin family
CAY59_RS13190	COG0457	Tetratricopeptide repeat
CAY59_RS13190	COG3118	belongs to the thioredoxin family
CAY59_RS13195	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CAY59_RS13200	COG1215	transferase activity, transferring glycosyl groups
CAY59_RS13205	COG1215	transferase activity, transferring glycosyl groups
CAY59_RS13210	COG1192	Involved in chromosome partitioning
CAY59_RS13225	COG2194	sulfuric ester hydrolase activity
CAY59_RS13230	COG0330	HflC and HflK could
CAY59_RS13265	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CAY59_RS13270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CAY59_RS13280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAY59_RS13285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CAY59_RS13290	COG2190	(PTS) system
CAY59_RS13295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CAY59_RS13300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CAY59_RS13305	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CAY59_RS13320	COG3951	Flagellar rod assembly protein muramidase FlgJ
CAY59_RS13320	COG1705	Flagellar rod assembly protein muramidase FlgJ
CAY59_RS13325	COG1706	bacterial-type flagellum-dependent cell motility
CAY59_RS13330	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CAY59_RS13340	COG4787	bacterial-type flagellum-dependent cell motility
CAY59_RS13345	COG1749	Flagellar hook protein flgE
CAY59_RS13355	COG1558	bacterial-type flagellum-dependent cell motility
CAY59_RS13360	COG1815	bacterial-type flagellum-dependent cell motility
CAY59_RS13365	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CAY59_RS13370	COG0835	chemotaxis
CAY59_RS13370	COG0784	Response regulator, receiver
CAY59_RS13435	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CAY59_RS13450	COG2217	Heavy metal translocating P-type atpase
CAY59_RS13450	COG2608	mercury ion transmembrane transporter activity
CAY59_RS13485	COG2840	Smr protein MutS2
CAY59_RS13490	COG1187	pseudouridine synthase activity
CAY59_RS13495	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CAY59_RS13500	COG0737	Belongs to the 5'-nucleotidase family
CAY59_RS13510	COG2912	Transglutaminase-like superfamily
CAY59_RS13515	COG3094	Invasion gene expression up-regulator, SirB
CAY59_RS13520	COG2890	protein-(glutamine-N5) methyltransferase activity
CAY59_RS13545	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CAY59_RS13670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAY59_RS13680	COG1702	phosphate starvation-inducible protein PhoH
CAY59_RS13690	COG4535	Mg2 and Co2 transporter CorC
CAY59_RS13695	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CAY59_RS13700	COG2888	peptidyl-tyrosine sulfation
CAY59_RS13710	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CAY59_RS13715	COG1466	dna polymerase III delta subunit
CAY59_RS13720	COG0799	negative regulation of ribosome biogenesis
CAY59_RS13730	COG0768	penicillin binding
CAY59_RS13735	COG0772	Belongs to the SEDS family
CAY59_RS13740	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CAY59_RS13745	COG1686	Belongs to the peptidase S11 family
CAY59_RS13765	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CAY59_RS13770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CAY59_RS13775	COG0366	Alpha amylase catalytic
CAY59_RS13780	COG1263	PTS System
CAY59_RS13780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAY59_RS13790	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CAY59_RS13795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CAY59_RS13800	COG2011	ABC-type metal ion transport system permease component
CAY59_RS13805	COG1464	Belongs to the NlpA lipoprotein family
CAY59_RS13815	COG0737	Belongs to the 5'-nucleotidase family
CAY59_RS13820	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CAY59_RS13845	COG1611	Belongs to the LOG family
CAY59_RS13860	COG2363	Small membrane protein
CAY59_RS13870	COG0583	DNA-binding transcription factor activity
CAY59_RS13885	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CAY59_RS13895	COG0142	geranyltranstransferase activity
CAY59_RS13905	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CAY59_RS13910	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CAY59_RS13935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CAY59_RS13935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CAY59_RS13940	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CAY59_RS13945	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CAY59_RS13960	COG1073	alpha beta
CAY59_RS13970	COG2252	PERMEase
CAY59_RS13975	COG2195	Cleaves the N-terminal amino acid of tripeptides
CAY59_RS14015	COG0590	tRNA wobble adenosine to inosine editing
CAY59_RS14025	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CAY59_RS14075	COG1301	dicarboxylic acid transport
CAY59_RS14090	COG0497	DNA recombination
CAY59_RS14095	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAY59_RS14100	COG2914	Belongs to the UPF0125 (RnfH) family
CAY59_RS14105	COG2867	negative regulation of translational initiation
CAY59_RS14120	COG0582	viral genome integration into host DNA
CAY59_RS14145	COG0732	type I restriction modification DNA specificity domain
CAY59_RS14150	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CAY59_RS14160	COG1401	restriction endodeoxyribonuclease activity
CAY59_RS14240	COG0583	DNA-binding transcription factor activity
CAY59_RS14245	COG1289	transmembrane transporter activity
CAY59_RS14265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CAY59_RS14270	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CAY59_RS14290	COG0583	DNA-binding transcription factor activity
CAY59_RS14300	COG1115	amino acid carrier protein
CAY59_RS14305	COG1584	GPR1 FUN34 yaaH family protein
CAY59_RS14315	COG1757	Na H antiporter
CAY59_RS14325	COG0517	IMP dehydrogenase activity
CAY59_RS14325	COG0516	GMP reductase activity
CAY59_RS14340	COG2203	Gaf domain
CAY59_RS14340	COG2199	diguanylate cyclase activity
CAY59_RS14355	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAY59_RS14360	COG2976	Protein conserved in bacteria
CAY59_RS14395	COG2975	iron-sulfur cluster assembly
CAY59_RS14400	COG0633	Ferredoxin
CAY59_RS14415	COG0316	Belongs to the HesB IscA family
CAY59_RS14420	COG0822	iron-sulfur transferase activity
CAY59_RS14435	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CAY59_RS14440	COG0483	inositol monophosphate 1-phosphatase activity
CAY59_RS14445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAY59_RS14450	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAY59_RS14455	COG1862	Preprotein translocase
CAY59_RS14480	COG0517	IMP dehydrogenase activity
CAY59_RS14490	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CAY59_RS14495	COG0583	DNA-binding transcription factor activity
CAY59_RS14500	COG0450	alkyl hydroperoxide reductase
CAY59_RS14525	COG0704	Plays a role in the regulation of phosphate uptake
CAY59_RS14530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CAY59_RS14535	COG0581	inorganic phosphate transmembrane transporter activity
CAY59_RS14540	COG0573	inorganic phosphate transmembrane transporter activity
CAY59_RS14545	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CAY59_RS14550	COG0248	Ppx GppA phosphatase
CAY59_RS14565	COG0745	RESPONSE REGULATOR receiver
CAY59_RS14575	COG0826	peptidase U32
CAY59_RS14580	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CAY59_RS14640	COG0542	response to heat
CAY59_RS14645	COG1496	oxidoreductase activity
CAY59_RS14650	COG0564	pseudouridine synthase activity
CAY59_RS14655	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAY59_RS14660	COG0741	lytic transglycosylase activity
CAY59_RS14665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CAY59_RS14670	COG1605	Chorismate mutase
CAY59_RS14670	COG0077	Prephenate dehydratase
CAY59_RS14675	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CAY59_RS14690	COG0488	(ABC) transporter
CAY59_RS14700	COG0739	heme binding
CAY59_RS14705	COG1605	Chorismate mutase
CAY59_RS14705	COG0287	Prephenate dehydrogenase
CAY59_RS14710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CAY59_RS14720	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CAY59_RS14740	COG1966	Carbon starvation protein
CAY59_RS14745	COG3275	phosphorelay sensor kinase activity
CAY59_RS14750	COG3279	Response regulator of the LytR AlgR family
CAY59_RS14755	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CAY59_RS14760	COG1047	Peptidyl-prolyl cis-trans
CAY59_RS14775	COG0196	riboflavin kinase activity
CAY59_RS14780	COG0728	peptidoglycan biosynthetic process
CAY59_RS14785	COG0268	Binds directly to 16S ribosomal RNA
CAY59_RS14790	COG0640	Transcriptional regulator
CAY59_RS14795	COG0583	DNA-binding transcription factor activity
CAY59_RS14800	COG1283	sodium-dependent phosphate transmembrane transporter activity
CAY59_RS14820	COG0730	response to heat
CAY59_RS14845	COG0667	Aldo Keto reductase
CAY59_RS14870	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CAY59_RS14875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CAY59_RS14880	COG4974	Belongs to the 'phage' integrase family
CAY59_RS14885	COG0716	FMN binding
CAY59_RS14900	COG0513	Belongs to the DEAD box helicase family
CAY59_RS14910	COG3022	response to hydroperoxide
CAY59_RS14915	COG1115	amino acid carrier protein
CAY59_RS14955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CAY59_RS14960	COG0083	homoserine kinase activity
CAY59_RS14975	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAY59_RS14990	COG0745	RESPONSE REGULATOR receiver
CAY59_RS15010	COG3706	GGDEF domain
CAY59_RS15010	COG4251	negative regulation of phosphorylation
CAY59_RS15010	COG5001	Diguanylate cyclase
CAY59_RS15010	COG2203	Gaf domain
CAY59_RS15015	COG1242	4 iron, 4 sulfur cluster binding
CAY59_RS15030	COG0070	glutamate synthase
CAY59_RS15030	COG0069	glutamate synthase activity
CAY59_RS15030	COG0067	glutamate synthase
CAY59_RS15035	COG0493	'glutamate synthase
CAY59_RS15060	COG2860	membrane
CAY59_RS15065	COG0583	DNA-binding transcription factor activity
CAY59_RS15070	COG0730	response to heat
CAY59_RS15090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CAY59_RS15095	COG0505	Belongs to the CarA family
CAY59_RS15105	COG0494	nUDIX hydrolase
CAY59_RS15125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CAY59_RS15130	COG0849	cell division
CAY59_RS15135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CAY59_RS15150	COG0772	Belongs to the SEDS family
CAY59_RS15165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CAY59_RS15170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CAY59_RS15175	COG0768	penicillin binding
CAY59_RS15180	COG3116	cell division
CAY59_RS15200	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CAY59_RS15215	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CAY59_RS15220	COG2823	Periplasmic or secreted lipoprotein
CAY59_RS15225	COG2969	positive regulation of protein catabolic process
CAY59_RS15230	COG0625	glutathione transferase activity
CAY59_RS15235	COG2857	Cytochrome c1
CAY59_RS15240	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CAY59_RS15245	COG0723	plastoquinol--plastocyanin reductase activity
CAY59_RS15260	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CAY59_RS15265	COG3105	Protein conserved in bacteria
CAY59_RS15270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAY59_RS15275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAY59_RS15280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CAY59_RS15290	COG3150	esterase
CAY59_RS15300	COG3151	Protein conserved in bacteria
CAY59_RS15305	COG0494	nUDIX hydrolase
CAY59_RS15310	COG1538	Outer membrane efflux protein
CAY59_RS15330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CAY59_RS15335	COG3025	triphosphatase activity
CAY59_RS15340	COG1392	Phosphate transport regulator
CAY59_RS15345	COG0306	phosphate transporter
CAY59_RS15350	COG4991	sh3 domain protein
CAY59_RS15365	COG3409	Peptidoglycan-binding domain 1 protein
CAY59_RS15365	COG3267	Type II secretory pathway component ExeA
CAY59_RS15380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CAY59_RS15385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CAY59_RS15395	COG0596	Alpha beta hydrolase
CAY59_RS15400	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CAY59_RS15405	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CAY59_RS15410	COG1610	YqeY-like protein
CAY59_RS15455	COG2213	PTS system mannitol-specific
CAY59_RS15455	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAY59_RS15465	COG3722	fumarate hydratase activity
CAY59_RS15470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CAY59_RS15495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CAY59_RS15500	COG1349	DNA-binding transcription factor activity
CAY59_RS15505	COG0469	pyruvate kinase activity
CAY59_RS15515	COG3706	GGDEF domain
CAY59_RS15520	COG0440	acetolactate synthase activity
CAY59_RS15525	COG0028	Belongs to the TPP enzyme family
CAY59_RS15530	COG1022	Amp-dependent synthetase and ligase
CAY59_RS15535	COG0583	DNA-binding transcription factor activity
CAY59_RS15565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CAY59_RS15570	COG0473	3-isopropylmalate dehydrogenase activity
CAY59_RS15590	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CAY59_RS15595	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CAY59_RS15600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAY59_RS15605	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CAY59_RS15625	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CAY59_RS15630	COG3610	response to peptide
CAY59_RS15635	COG2966	Psort location CytoplasmicMembrane, score
CAY59_RS15650	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CAY59_RS15655	COG0142	geranyltranstransferase activity
CAY59_RS15675	COG2358	TRAP transporter, solute receptor (TAXI family
CAY59_RS15690	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CAY59_RS15695	COG1178	ABC-type Fe3 transport system permease component
CAY59_RS15700	COG4143	(ABC) transporter
CAY59_RS15705	COG0163	prenyltransferase activity
CAY59_RS15710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CAY59_RS15720	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CAY59_RS15735	COG2105	PFAM AIG2 family protein
CAY59_RS15745	COG0729	surface antigen
CAY59_RS15750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAY59_RS15760	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CAY59_RS15775	COG1136	(ABC) transporter
CAY59_RS15795	COG0529	Catalyzes the synthesis of activated sulfate
CAY59_RS15800	COG3273	potassium ion transport
CAY59_RS15800	COG0471	metal ion transport
CAY59_RS15815	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CAY59_RS15815	COG1648	precorrin-2 dehydrogenase activity
CAY59_RS15820	COG0737	Belongs to the 5'-nucleotidase family
CAY59_RS15830	COG0513	Belongs to the DEAD box helicase family
CAY59_RS15835	COG2153	protein acetylation
CAY59_RS15850	COG0545	Peptidyl-prolyl cis-trans isomerase
CAY59_RS15860	COG0203	ribosomal protein L17
CAY59_RS15865	COG0202	RNA polymerase activity
CAY59_RS15875	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CAY59_RS15880	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CAY59_RS15885	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CAY59_RS15890	COG0201	protein transport
CAY59_RS15900	COG1841	ribosomal large subunit assembly
CAY59_RS15985	COG0088	Forms part of the polypeptide exit tunnel
CAY59_RS16005	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CAY59_RS16010	COG1609	Transcriptional regulator
CAY59_RS16030	COG1575	Belongs to the MenA family. Type 1 subfamily
CAY59_RS16035	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAY59_RS16045	COG1494	fructose-1,6-bisphosphatase
CAY59_RS16070	COG0149	triose-phosphate isomerase activity
CAY59_RS16095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CAY59_RS16100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CAY59_RS16125	COG1086	Polysaccharide biosynthesis protein
CAY59_RS16150	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CAY59_RS16155	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CAY59_RS16160	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CAY59_RS16165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CAY59_RS16170	COG1482	cell wall glycoprotein biosynthetic process
CAY59_RS16205	COG1215	transferase activity, transferring glycosyl groups
CAY59_RS16255	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAY59_RS16265	COG1560	Kdo2-lipid A biosynthetic process
CAY59_RS16270	COG0859	PFAM glycosyl transferase family 9
CAY59_RS16275	COG1519	Transferase
CAY59_RS16280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CAY59_RS16285	COG0110	maltose O-acetyltransferase activity
CAY59_RS16290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CAY59_RS16295	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CAY59_RS16310	COG3642	lipopolysaccharide core region biosynthetic process
CAY59_RS16315	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CAY59_RS16320	COG0438	transferase activity, transferring glycosyl groups
CAY59_RS16325	COG0859	PFAM glycosyl transferase family 9
CAY59_RS16375	COG0840	transmembrane signaling receptor activity
CAY59_RS16385	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CAY59_RS16395	COG1560	Kdo2-lipid A biosynthetic process
CAY59_RS16400	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CAY59_RS16410	COG1561	YicC-like family, N-terminal region
CAY59_RS16430	COG4608	Belongs to the ABC transporter superfamily
CAY59_RS16435	COG0444	Belongs to the ABC transporter superfamily
CAY59_RS16440	COG0747	negative chemotaxis
CAY59_RS16445	COG4239	(ABC) transporter, permease
CAY59_RS16450	COG4174	ABC transporter (Permease)
CAY59_RS16460	COG4206	TonB-dependent receptor
CAY59_RS16475	COG0811	peptide transport
CAY59_RS16480	COG0848	biopolymer transport protein
CAY59_RS16495	COG0194	GDP metabolic process
CAY59_RS16500	COG1758	RNA polymerase activity
CAY59_RS16505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CAY59_RS16510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAY59_RS16515	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CAY59_RS16525	COG2233	PERMEase
CAY59_RS16540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CAY59_RS16550	COG2183	response to ionizing radiation
CAY59_RS16565	COG1040	competence protein
CAY59_RS16575	COG0494	nUDIX hydrolase
CAY59_RS16580	COG1218	3'(2'),5'-bisphosphate nucleotidase
CAY59_RS16590	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CAY59_RS16595	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CAY59_RS16600	COG3156	type II secretion system protein K
CAY59_RS16605	COG4795	General secretion pathway protein
CAY59_RS16610	COG2165	general secretion pathway protein
CAY59_RS16615	COG2165	general secretion pathway protein
CAY59_RS16620	COG2165	general secretion pathway protein
CAY59_RS16625	COG1459	type II secretion system
CAY59_RS16630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CAY59_RS16640	COG3031	protein transport across the cell outer membrane
CAY59_RS16645	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CAY59_RS16665	COG0456	acetyltransferase
CAY59_RS16670	COG1490	D-aminoacyl-tRNA deacylase activity
CAY59_RS16700	COG0174	glutamine synthetase
CAY59_RS16710	COG3852	Histidine kinase
CAY59_RS16715	COG2204	response regulator
CAY59_RS16720	COG3300	MHYT domain
CAY59_RS16720	COG5001	Diguanylate cyclase
CAY59_RS16725	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CAY59_RS16760	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CAY59_RS16770	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CAY59_RS16770	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CAY59_RS16795	COG0084	hydrolase, TatD family'
CAY59_RS16810	COG0805	protein transport
CAY59_RS16815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CAY59_RS16830	COG3165	ubiquinone biosynthetic process from chorismate
CAY59_RS16855	COG1910	domain protein
CAY59_RS16875	COG2081	HI0933 family
CAY59_RS16890	COG0732	type I restriction modification DNA specificity domain
CAY59_RS16970	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CAY59_RS16975	COG0732	type I restriction modification DNA specificity domain
CAY59_RS17010	COG2204	response regulator
CAY59_RS17025	COG3501	Rhs element vgr protein
CAY59_RS17050	COG0515	serine threonine protein kinase
CAY59_RS17080	COG1522	sequence-specific DNA binding
CAY59_RS17155	COG4771	TonB-dependent receptor
CAY59_RS17170	COG2205	protein histidine kinase activity
CAY59_RS17170	COG0784	Response regulator, receiver
CAY59_RS17175	COG3300	MHYT domain
CAY59_RS17175	COG5001	Diguanylate cyclase
CAY59_RS17180	COG2197	response regulator
CAY59_RS17185	COG3706	GGDEF domain
CAY59_RS17195	COG2197	response regulator
CAY59_RS17200	COG0778	Nitroreductase
CAY59_RS17210	COG0784	Response regulator, receiver
CAY59_RS17210	COG0835	chemotaxis
CAY59_RS17215	COG2165	general secretion pathway protein
CAY59_RS17225	COG2962	Rard protein
CAY59_RS17240	COG0671	phosphoesterase, PA-phosphatase related
CAY59_RS17295	COG2067	long-chain fatty acid transport protein
CAY59_RS17300	COG1234	tRNA 3'-trailer cleavage
CAY59_RS17315	COG5642	Protein of unknown function (DUF2384)
CAY59_RS17325	COG2755	lipolytic protein G-D-S-L family
CAY59_RS17325	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CAY59_RS17335	COG1902	pentaerythritol trinitrate reductase activity
CAY59_RS17340	COG0346	lactoylglutathione lyase activity
CAY59_RS17370	COG2815	serine threonine protein kinase
CAY59_RS17370	COG0515	serine threonine protein kinase
CAY59_RS17405	COG0631	protein serine/threonine phosphatase activity
CAY59_RS17475	COG3209	COG3209 Rhs family protein
CAY59_RS17495	COG0420	3'-5' exonuclease activity
CAY59_RS17500	COG0419	ATPase involved in DNA repair
CAY59_RS17510	COG3469	chitinase activity
CAY59_RS17540	COG3040	lipid binding
CAY59_RS17550	COG2814	Major facilitator Superfamily
CAY59_RS17560	COG1288	antiporter activity
CAY59_RS17570	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CAY59_RS17585	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CAY59_RS17600	COG1472	Belongs to the glycosyl hydrolase 3 family
CAY59_RS17605	COG0583	DNA-binding transcription factor activity
CAY59_RS17695	COG2199	diguanylate cyclase activity
CAY59_RS17705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAY59_RS17715	COG2116	formate transmembrane transporter activity
CAY59_RS17735	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CAY59_RS17760	COG0534	Mate efflux family protein
CAY59_RS17765	COG3292	Two component regulator propeller
CAY59_RS17765	COG0745	RESPONSE REGULATOR receiver
CAY59_RS17765	COG2205	protein histidine kinase activity
CAY59_RS17775	COG3118	belongs to the thioredoxin family
CAY59_RS17780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CAY59_RS17805	COG1566	PFAM secretion protein HlyD family protein
CAY59_RS17825	COG1482	cell wall glycoprotein biosynthetic process
CAY59_RS17835	COG3851	Histidine kinase
CAY59_RS17840	COG2197	response regulator
CAY59_RS17905	COG1328	CTP reductase activity
CAY59_RS17910	COG0602	queuosine metabolic process
CAY59_RS17940	COG3111	PFAM Bacterial OB fold (BOF) protein
CAY59_RS17950	COG0725	ABC transporter, periplasmic molybdate-binding protein
CAY59_RS17955	COG4149	molybdate abc transporter
CAY59_RS17960	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CAY59_RS17970	COG5001	Diguanylate cyclase
CAY59_RS17970	COG2203	Gaf domain
CAY59_RS17970	COG3706	GGDEF domain
CAY59_RS17970	COG4251	negative regulation of phosphorylation
CAY59_RS17990	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CAY59_RS17995	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CAY59_RS18020	COG3140	Belongs to the UPF0181 family
CAY59_RS18110	COG0023	Translation Initiation Factor
CAY59_RS18130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAY59_RS18130	COG1042	CoA-binding domain protein
CAY59_RS18130	COG0045	succinate-CoA ligase (ADP-forming) activity
CAY59_RS18135	COG0583	DNA-binding transcription factor activity
CAY59_RS18150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CAY59_RS18165	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CAY59_RS18170	COG1984	allophanate hydrolase subunit 2
CAY59_RS18180	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CAY59_RS18185	COG4181	ATPase activity
CAY59_RS18195	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CAY59_RS18200	COG5001	Diguanylate cyclase
CAY59_RS18200	COG3300	MHYT domain
CAY59_RS18210	COG0484	heat shock protein binding
CAY59_RS18245	COG2050	protein possibly involved in aromatic compounds catabolism
CAY59_RS18250	COG0501	Belongs to the peptidase M48B family
CAY59_RS18260	COG2067	long-chain fatty acid transport protein
CAY59_RS18265	COG2267	carboxylic ester hydrolase activity
CAY59_RS18280	COG0646	methionine synthase
CAY59_RS18280	COG1410	methionine synthase
CAY59_RS18290	COG0861	Integral membrane protein TerC family
CAY59_RS18295	COG0737	Belongs to the 5'-nucleotidase family
CAY59_RS18300	COG3593	DNA synthesis involved in DNA repair
CAY59_RS18310	COG0583	DNA-binding transcription factor activity
CAY59_RS18320	COG2116	formate transmembrane transporter activity
CAY59_RS18330	COG3038	cytochrome b561
CAY59_RS18345	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CAY59_RS18350	COG0513	Belongs to the DEAD box helicase family
CAY59_RS18355	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CAY59_RS18365	COG0840	transmembrane signaling receptor activity
CAY59_RS18370	COG0546	phosphoglycolate phosphatase activity
CAY59_RS18375	COG0784	Response regulator, receiver
CAY59_RS18375	COG3437	response regulator, receiver
CAY59_RS18390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAY59_RS18400	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CAY59_RS18415	COG2207	Transcriptional regulator
CAY59_RS18420	COG1979	alcohol dehydrogenase
CAY59_RS18430	COG1126	abc transporter atp-binding protein
CAY59_RS18435	COG0765	amino acid transport
CAY59_RS18440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAY59_RS18450	COG2203	Gaf domain
CAY59_RS18450	COG2199	diguanylate cyclase activity
CAY59_RS18450	COG2200	EAL domain
CAY59_RS18465	COG1609	Transcriptional regulator
CAY59_RS18470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAY59_RS18470	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAY59_RS18475	COG1105	Belongs to the carbohydrate kinase PfkB family
CAY59_RS18480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAY59_RS18480	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CAY59_RS18480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAY59_RS18495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAY59_RS18500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAY59_RS18510	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CAY59_RS18520	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CAY59_RS18595	COG4977	sequence-specific DNA binding
CAY59_RS18605	COG1733	regulation of RNA biosynthetic process
CAY59_RS18615	COG0641	radical SAM
CAY59_RS18620	COG3119	arylsulfatase activity
CAY59_RS18625	COG3119	arylsulfatase activity
CAY59_RS18645	COG0583	DNA-binding transcription factor activity
CAY59_RS18660	COG5640	endopeptidase activity
CAY59_RS18670	COG1132	(ABC) transporter
CAY59_RS18715	COG2814	Major facilitator Superfamily
CAY59_RS18800	COG0628	permease
CAY59_RS18850	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CAY59_RS18885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAY59_RS18885	COG2146	nitrite reductase [NAD(P)H] activity
CAY59_RS18890	COG1116	anion transmembrane transporter activity
CAY59_RS18895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAY59_RS18900	COG1116	anion transmembrane transporter activity
CAY59_RS18900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CAY59_RS18905	COG3707	response regulator
CAY59_RS18925	COG0243	molybdopterin cofactor binding
CAY59_RS18930	COG0456	acetyltransferase
CAY59_RS18935	COG5002	protein histidine kinase activity
CAY59_RS18935	COG5001	Diguanylate cyclase
CAY59_RS18940	COG0814	amino acid
CAY59_RS18970	COG1785	Belongs to the alkaline phosphatase family
CAY59_RS18985	COG0745	RESPONSE REGULATOR receiver
CAY59_RS19025	COG0443	Heat shock 70 kDa protein
CAY59_RS19070	COG2200	EAL domain
CAY59_RS19095	COG4160	amino acid transport
CAY59_RS19100	COG4215	(ABC) transporter
CAY59_RS19105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAY59_RS19110	COG1126	abc transporter atp-binding protein
CAY59_RS19165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CAY59_RS19175	COG1012	belongs to the aldehyde dehydrogenase family
CAY59_RS19190	COG0446	pyridine nucleotide-disulphide oxidoreductase
CAY59_RS19190	COG1902	pentaerythritol trinitrate reductase activity
CAY59_RS19205	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CAY59_RS19210	COG1845	cytochrome c oxidase, subunit III
CAY59_RS19215	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CAY59_RS19220	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CAY59_RS19230	COG1028	Short-chain dehydrogenase reductase Sdr
CAY59_RS19240	COG1024	Enoyl-CoA hydratase
CAY59_RS19245	COG1024	Enoyl-CoA hydratase
CAY59_RS19260	COG0183	Belongs to the thiolase family
CAY59_RS19270	COG1960	acyl-CoA dehydrogenase activity
CAY59_RS19275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CAY59_RS19280	COG1024	Enoyl-CoA hydratase
CAY59_RS19320	COG3278	Belongs to the heme-copper respiratory oxidase family
CAY59_RS19335	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CAY59_RS19345	COG0513	Belongs to the DEAD box helicase family
CAY59_RS19365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CAY59_RS19380	COG1119	ATPase activity
CAY59_RS19385	COG2200	EAL domain
CAY59_RS19405	COG0513	Belongs to the DEAD box helicase family
CAY59_RS19410	COG5002	protein histidine kinase activity
CAY59_RS19410	COG5001	Diguanylate cyclase
CAY59_RS19410	COG3447	MASE1 domain protein
CAY59_RS19415	COG0523	cobalamin synthesis protein
CAY59_RS19445	COG3530	Putative quorum-sensing-regulated virulence factor
CAY59_RS19475	COG3186	Phenylalanine-4-hydroxylase
CAY59_RS19485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CAY59_RS19490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CAY59_RS19510	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CAY59_RS19515	COG1454	alcohol dehydrogenase
CAY59_RS19520	COG2133	pyrroloquinoline quinone binding
CAY59_RS19525	COG1619	proteins homologs of microcin C7 resistance protein MccF
CAY59_RS19535	COG0783	Belongs to the Dps family
CAY59_RS19540	COG0840	transmembrane signaling receptor activity
CAY59_RS19550	COG0577	efflux transmembrane transporter activity
CAY59_RS19550	COG1136	(ABC) transporter
CAY59_RS19570	COG2199	diguanylate cyclase activity
CAY59_RS19580	COG3036	rescue of stalled ribosome
CAY59_RS19585	COG1278	Cold shock
CAY59_RS19615	COG0545	Peptidyl-prolyl cis-trans isomerase
CAY59_RS19620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CAY59_RS19655	COG2195	Cleaves the N-terminal amino acid of tripeptides
CAY59_RS19670	COG2197	response regulator
CAY59_RS19680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CAY59_RS19700	COG3005	denitrification pathway
CAY59_RS19720	COG0183	Belongs to the thiolase family
CAY59_RS19730	COG1280	lysine exporter protein (LysE YggA)
CAY59_RS19740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAY59_RS19745	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAY59_RS19830	COG0673	inositol 2-dehydrogenase activity
CAY59_RS19835	COG5002	protein histidine kinase activity
CAY59_RS19835	COG0784	Response regulator, receiver
CAY59_RS19835	COG2205	protein histidine kinase activity
CAY59_RS19855	COG0583	DNA-binding transcription factor activity
CAY59_RS19870	COG0531	amino acid
CAY59_RS19885	COG2205	protein histidine kinase activity
CAY59_RS19890	COG0745	RESPONSE REGULATOR receiver
CAY59_RS19915	COG1566	PFAM secretion protein HlyD family protein
CAY59_RS19920	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CAY59_RS19925	COG2239	Acts as a magnesium transporter
CAY59_RS19930	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CAY59_RS19935	COG0402	S-adenosylhomocysteine deaminase activity
CAY59_RS19950	COG1418	mRNA catabolic process
CAY59_RS19965	COG2814	Major facilitator Superfamily
CAY59_RS19975	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CAY59_RS19995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CAY59_RS20010	COG4221	oxidoreductase activity
CAY59_RS20015	COG0745	RESPONSE REGULATOR receiver
CAY59_RS20020	COG2205	protein histidine kinase activity
CAY59_RS20030	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CAY59_RS20035	COG2194	sulfuric ester hydrolase activity
CAY59_RS20045	COG0673	inositol 2-dehydrogenase activity
CAY59_RS20050	COG4977	sequence-specific DNA binding
CAY59_RS20065	COG2814	Major facilitator Superfamily
CAY59_RS20085	COG0583	DNA-binding transcription factor activity
CAY59_RS20090	COG2249	NAD(P)H dehydrogenase (quinone) activity
CAY59_RS20105	COG0583	DNA-binding transcription factor activity
CAY59_RS20145	COG0366	Alpha amylase catalytic
CAY59_RS20150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAY59_RS20155	COG0784	Response regulator, receiver
CAY59_RS20155	COG0835	chemotaxis
CAY59_RS20170	COG0748	coenzyme F420 binding
CAY59_RS20175	COG3721	Heme iron utilization protein
CAY59_RS20185	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CAY59_RS20190	COG0811	peptide transport
CAY59_RS20195	COG0848	biopolymer transport protein
CAY59_RS20205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAY59_RS20210	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CAY59_RS20250	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CAY59_RS20260	COG3217	Mosc domain protein beta barrel domain protein
CAY59_RS20260	COG0633	Ferredoxin
CAY59_RS20260	COG0633	Ferredoxin
CAY59_RS20260	COG3217	Mosc domain protein beta barrel domain protein
CAY59_RS20265	COG0401	homolog of Blt101
CAY59_RS20305	COG3833	ABC-type maltose transport systems, permease component
CAY59_RS20310	COG1175	transmembrane transport
CAY59_RS20325	COG3842	ATPase activity
CAY59_RS20365	COG3206	protein involved in exopolysaccharide biosynthesis
CAY59_RS20365	COG0489	protein tyrosine kinase activity
CAY59_RS20410	COG1309	transcriptional regulator
CAY59_RS20415	COG2130	NADP-dependent
CAY59_RS20425	COG0753	catalase activity
CAY59_RS20430	COG2084	Dehydrogenase
CAY59_RS20440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAY59_RS20445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAY59_RS20510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CAY59_RS20515	COG1301	dicarboxylic acid transport
CAY59_RS20520	COG1252	NADH dehydrogenase
CAY59_RS20530	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CAY59_RS20535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CAY59_RS20585	COG1028	Short-chain dehydrogenase reductase Sdr
CAY59_RS20590	COG3852	Histidine kinase
CAY59_RS20600	COG0110	maltose O-acetyltransferase activity
CAY59_RS20625	COG2197	response regulator
CAY59_RS20655	COG0714	Associated with various cellular activities
CAY59_RS20675	COG2304	oxidoreductase activity
CAY59_RS20690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CAY59_RS20695	COG0581	inorganic phosphate transmembrane transporter activity
CAY59_RS20700	COG0573	inorganic phosphate transmembrane transporter activity
CAY59_RS20730	COG4771	TonB-dependent receptor
CAY59_RS20735	COG1770	oligopeptidase
CAY59_RS20740	COG0513	Belongs to the DEAD box helicase family
CAY59_RS20750	COG1376	ErfK ybiS ycfS ynhG family protein
CAY59_RS20750	COG1388	LysM domain
CAY59_RS20755	COG0415	Belongs to the DNA photolyase family
CAY59_RS20760	COG0789	Transcriptional regulator
CAY59_RS20765	COG3272	Protein of unknown function (DUF1722)
CAY59_RS20770	COG0813	purine-nucleoside phosphorylase activity
CAY59_RS20800	COG1566	PFAM secretion protein HlyD family protein
CAY59_RS20810	COG1122	ATPase activity
CAY59_RS20840	COG0348	domain, Protein
CAY59_RS20845	COG0437	4 iron, 4 sulfur cluster binding
CAY59_RS20850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAY59_RS20870	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAY59_RS20880	COG1067	ATP-dependent peptidase activity
CAY59_RS20890	COG4172	Belongs to the ABC transporter superfamily
CAY59_RS20895	COG1505	serine-type exopeptidase activity
CAY59_RS20900	COG0583	DNA-binding transcription factor activity
CAY59_RS20910	COG1304	FMN binding
CAY59_RS20920	COG0668	transmembrane transport
CAY59_RS20930	COG1063	alcohol dehydrogenase
CAY59_RS20935	COG2223	nitrite transmembrane transporter activity
CAY59_RS20940	COG2203	Gaf domain
CAY59_RS20940	COG2199	diguanylate cyclase activity
CAY59_RS20965	COG1063	alcohol dehydrogenase
CAY59_RS21135	COG1403	HNH endonuclease
CAY59_RS21160	COG1802	Transcriptional regulator
CAY59_RS21160	COG4626	Terminase
CAY59_RS21195	COG2815	serine threonine protein kinase
CAY59_RS21195	COG0515	serine threonine protein kinase
CAY59_RS21210	COG5532	Uncharacterized conserved protein (DUF2303)
CAY59_RS21230	COG0582	viral genome integration into host DNA
CAY59_RS21245	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CAY59_RS21270	COG1063	alcohol dehydrogenase
CAY59_RS21275	COG0156	8-amino-7-oxononanoate synthase activity
CAY59_RS21300	COG0745	RESPONSE REGULATOR receiver
CAY59_RS21325	COG0346	lactoylglutathione lyase activity
CAY59_RS21390	COG3121	Chaperone
CAY59_RS21400	COG3188	usher protein
CAY59_RS21405	COG3121	Chaperone
CAY59_RS21430	COG2200	EAL domain
CAY59_RS21490	COG1987	bacterial-type flagellum assembly
CAY59_RS21500	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CAY59_RS21515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CAY59_RS21525	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CAY59_RS21530	COG1516	flagellar protein fliS
CAY59_RS21545	COG1580	Controls the rotational direction of flagella during chemotaxis
CAY59_RS21550	COG1191	sigma factor activity
CAY59_RS21555	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CAY59_RS21560	COG1360	Flagellar Motor Protein
CAY59_RS21585	COG0384	phenazine biosynthesis protein PhzF
CAY59_RS21630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAY59_RS21640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAY59_RS21645	COG1473	amidohydrolase
CAY59_RS21655	COG1522	sequence-specific DNA binding
CAY59_RS21695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CAY59_RS21700	COG4786	Flagellar basal body rod
CAY59_RS21700	COG1256	bacterial-type flagellum assembly
CAY59_RS21715	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CAY59_RS21720	COG4786	Flagellar basal body rod
CAY59_RS21725	COG4787	bacterial-type flagellum-dependent cell motility
CAY59_RS21730	COG1749	Flagellar hook protein flgE
CAY59_RS21735	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CAY59_RS21740	COG1558	bacterial-type flagellum-dependent cell motility
CAY59_RS21745	COG1815	bacterial-type flagellum-dependent cell motility
CAY59_RS21765	COG0741	lytic transglycosylase activity
CAY59_RS21765	COG1388	LysM domain
CAY59_RS21790	COG1760	l-serine dehydratase
CAY59_RS21795	COG3104	oligopeptide transport
CAY59_RS21820	COG0583	DNA-binding transcription factor activity
CAY59_RS21830	COG2866	Carboxypeptidase
CAY59_RS21835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAY59_RS21845	COG2990	Protein conserved in bacteria
CAY59_RS21870	COG3842	ATPase activity
CAY59_RS21880	COG1840	ABC-type Fe3 transport system, periplasmic component
CAY59_RS21890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CAY59_RS21900	COG1609	Transcriptional regulator
CAY59_RS21955	COG1011	Hydrolase
CAY59_RS21990	COG1765	OsmC-like protein
CAY59_RS21995	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAY59_RS21995	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAY59_RS22010	COG3046	protein related to deoxyribodipyrimidine photolyase
CAY59_RS22015	COG0415	Belongs to the DNA photolyase family
CAY59_RS22020	COG3706	GGDEF domain
CAY59_RS22055	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CAY59_RS22060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CAY59_RS22080	COG3033	Beta-eliminating lyase
CAY59_RS22095	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CAY59_RS22100	COG0579	oxidoreductase
CAY59_RS22115	COG1114	Component of the transport system for branched-chain amino acids
CAY59_RS22160	COG0583	DNA-binding transcription factor activity
CAY59_RS22170	COG0189	ligase activity
CAY59_RS22175	COG4067	protein conserved in archaea
CAY59_RS22175	COG0189	ligase activity
CAY59_RS22185	COG1166	arginine decarboxylase activity
CAY59_RS22190	COG0010	Belongs to the arginase family
CAY59_RS22195	COG2814	Major facilitator Superfamily
CAY59_RS22200	COG1770	oligopeptidase
CAY59_RS22215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CAY59_RS22220	COG1121	(ABC) transporter
CAY59_RS22225	COG0803	Belongs to the bacterial solute-binding protein 9 family
CAY59_RS22270	COG0848	biopolymer transport protein
CAY59_RS22275	COG0811	peptide transport
CAY59_RS22280	COG0811	peptide transport
CAY59_RS22300	COG0745	RESPONSE REGULATOR receiver
CAY59_RS22305	COG0584	glycerophosphoryl diester phosphodiesterase
CAY59_RS22315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAY59_RS22380	COG0312	modulator of DNA gyrase
CAY59_RS22385	COG0312	modulator of DNA gyrase
CAY59_RS22395	COG0351	phosphomethylpyrimidine kinase
CAY59_RS22400	COG1116	anion transmembrane transporter activity
CAY59_RS22405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAY59_RS22410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CAY59_RS22415	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CAY59_RS22430	COG0671	phosphoesterase, PA-phosphatase related
CAY59_RS22435	COG0243	molybdopterin cofactor binding
CAY59_RS22440	COG3005	denitrification pathway
CAY59_RS22450	COG1028	Short-chain dehydrogenase reductase Sdr
CAY59_RS22470	COG0456	acetyltransferase
CAY59_RS22510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAY59_RS22515	COG1929	Belongs to the glycerate kinase type-1 family
CAY59_RS22520	COG3835	regulator
CAY59_RS22600	COG0583	DNA-binding transcription factor activity
CAY59_RS22630	COG3408	Glycogen debranching enzyme
CAY59_RS22630	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CAY59_RS22650	COG2814	Major facilitator Superfamily
CAY59_RS22660	COG3047	cAMP biosynthetic process
CAY59_RS22665	COG1357	PFAM Pentapeptide repeats (8 copies)
CAY59_RS22680	COG0534	Mate efflux family protein
CAY59_RS22695	COG2076	Multidrug Resistance protein
CAY59_RS22750	COG0583	DNA-binding transcription factor activity
CAY59_RS22770	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CAY59_RS22785	COG3152	Membrane
CAY59_RS22805	COG0561	phosphatase activity
CAY59_RS22815	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CAY59_RS22820	COG0564	pseudouridine synthase activity
CAY59_RS22825	COG0534	Mate efflux family protein
CAY59_RS22830	COG1472	Belongs to the glycosyl hydrolase 3 family
CAY59_RS22845	COG1609	Transcriptional regulator
CAY59_RS22855	COG4608	Belongs to the ABC transporter superfamily
CAY59_RS22860	COG0444	Belongs to the ABC transporter superfamily
CAY59_RS22865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAY59_RS22875	COG0747	negative chemotaxis
CAY59_RS22885	COG1609	Transcriptional regulator
CAY59_RS22890	COG3842	ATPase activity
CAY59_RS22895	COG2723	6-phospho-beta-galactosidase activity
CAY59_RS22900	COG0395	ABC-type sugar transport system, permease component
CAY59_RS22915	COG1609	Transcriptional regulator
CAY59_RS22925	COG5001	Diguanylate cyclase
CAY59_RS22975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CAY59_RS22985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CAY59_RS22990	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CAY59_RS23000	COG2259	Doxx family
CAY59_RS23055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CAY59_RS23060	COG0251	oxidation-reduction process
CAY59_RS23075	COG0659	secondary active sulfate transmembrane transporter activity
CAY59_RS23095	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CAY59_RS23100	COG2207	Transcriptional regulator
CAY59_RS23110	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CAY59_RS23115	COG0830	nickel cation binding
CAY59_RS23120	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CAY59_RS23125	COG0804	urea catabolic process
CAY59_RS23130	COG0832	Belongs to the urease beta subunit family
CAY59_RS23135	COG0831	urea catabolic process
CAY59_RS23140	COG0829	nickel cation binding
CAY59_RS23155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CAY59_RS23180	COG0786	glutamate:sodium symporter activity
CAY59_RS23185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAY59_RS23190	COG1131	(ABC) transporter
CAY59_RS23225	COG1028	Short-chain dehydrogenase reductase Sdr
CAY59_RS23230	COG0786	glutamate:sodium symporter activity
CAY59_RS23250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CAY59_RS23260	COG3279	Response regulator of the LytR AlgR family
CAY59_RS23265	COG3275	phosphorelay sensor kinase activity
CAY59_RS23285	COG1136	(ABC) transporter
CAY59_RS23300	COG1566	PFAM secretion protein HlyD family protein
CAY59_RS23315	COG0772	Belongs to the SEDS family
CAY59_RS23340	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CAY59_RS23340	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CAY59_RS23350	COG0444	Belongs to the ABC transporter superfamily
CAY59_RS23355	COG4608	Belongs to the ABC transporter superfamily
CAY59_RS23390	COG1444	tRNA N-acetyltransferase activity
CAY59_RS23415	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAY59_RS23420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAY59_RS23420	COG1263	PTS System
CAY59_RS23425	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CAY59_RS23440	COG4166	transmembrane transport
CAY59_RS23565	COG1132	(ABC) transporter
CAY59_RS23600	COG0800	Aldolase
CAY59_RS23605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAY59_RS23610	COG1904	glucuronate isomerase
CAY59_RS23615	COG0246	Mannitol dehydrogenase
CAY59_RS23625	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CAY59_RS23635	COG2186	Transcriptional regulator
CAY59_RS23640	COG1312	Catalyzes the dehydration of D-mannonate
CAY59_RS23660	COG0513	Belongs to the DEAD box helicase family
CAY59_RS23665	COG3713	MltA-interacting MipA family protein
CAY59_RS23675	COG2153	protein acetylation
CAY59_RS23680	COG2258	MOSC domain
CAY59_RS23695	COG0544	peptidyl-prolyl cis-trans isomerase activity
CAY59_RS23700	COG1522	sequence-specific DNA binding
CAY59_RS23710	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CAY59_RS23755	COG0366	Alpha amylase catalytic
CAY59_RS23760	COG0583	DNA-binding transcription factor activity
CAY59_RS23765	COG1349	DNA-binding transcription factor activity
CAY59_RS23770	COG2084	Dehydrogenase
CAY59_RS23785	COG3622	Belongs to the hyi family
CAY59_RS23790	COG2610	gluconate transmembrane transporter activity
CAY59_RS23830	COG3634	alkyl hydroperoxide reductase activity
CAY59_RS23840	COG1846	Transcriptional regulator
CAY59_RS23845	COG1764	response to oxidative stress
CAY59_RS23880	COG0577	efflux transmembrane transporter activity
CAY59_RS23890	COG1335	isochorismatase
CAY59_RS23905	COG0463	Glycosyl transferase, family 2
CAY59_RS23930	COG0826	peptidase U32
CAY59_RS23940	COG0840	transmembrane signaling receptor activity
CAY59_RS23945	COG0612	Peptidase, M16
CAY59_RS23970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAY59_RS23975	COG0383	alpha-mannosidase activity
CAY59_RS23985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAY59_RS23985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAY59_RS23985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAY59_RS24010	COG3188	usher protein
CAY59_RS24015	COG3121	Chaperone
CAY59_RS24040	COG2188	Transcriptional regulator
CAY59_RS24050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAY59_RS24050	COG2190	(PTS) system
CAY59_RS24050	COG1263	PTS System
CAY59_RS24055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAY59_RS24060	COG0800	Aldolase
CAY59_RS24075	COG0739	heme binding
CAY59_RS24105	COG2814	Major facilitator Superfamily
CAY59_RS24115	COG1609	Transcriptional regulator
CAY59_RS24140	COG1760	l-serine dehydratase
CAY59_RS24150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CAY59_RS24165	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CAY59_RS24165	COG1648	precorrin-2 dehydrogenase activity
CAY59_RS24170	COG2199	diguanylate cyclase activity
CAY59_RS24170	COG2203	Gaf domain
CAY59_RS24180	COG4580	involved in the transport of maltose and maltodextrins
CAY59_RS24200	COG2356	endonuclease I
CAY59_RS24220	COG1982	Orn Lys Arg decarboxylase major
CAY59_RS24225	COG0531	amino acid
CAY59_RS24250	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CAY59_RS24255	COG0183	Belongs to the thiolase family
CAY59_RS24275	COG2814	Major facilitator Superfamily
CAY59_RS24275	COG0477	Major facilitator Superfamily
CAY59_RS24285	COG3962	Belongs to the TPP enzyme family
CAY59_RS24290	COG0673	inositol 2-dehydrogenase activity
CAY59_RS24295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAY59_RS24320	COG0673	inositol 2-dehydrogenase activity
CAY59_RS24330	COG1162	GTPase activity
CAY59_RS24335	COG1263	PTS System
CAY59_RS24335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CAY59_RS24345	COG1999	signal sequence binding
CAY59_RS24370	COG0058	SHG alpha-glucan phosphorylase activity
CAY59_RS24375	COG1640	4-alpha-glucanotransferase
CAY59_RS24380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CAY59_RS24385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CAY59_RS24390	COG0366	Alpha amylase catalytic
CAY59_RS24405	COG3366	ferrous iron transmembrane transporter activity
CAY59_RS24410	COG0700	Nucleoside recognition
CAY59_RS24415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAY59_RS24420	COG3339	Conserved Protein
CAY59_RS24425	COG1301	dicarboxylic acid transport
CAY59_RS24460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CAY59_RS24465	COG1596	polysaccharide export
CAY59_RS24480	COG2095	MarC family integral membrane protein
CAY59_RS24485	COG4667	esterase of the alpha-beta hydrolase superfamily
CAY59_RS24495	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CAY59_RS24500	COG0415	Belongs to the DNA photolyase family
CAY59_RS24525	COG1686	Belongs to the peptidase S11 family
CAY59_RS24535	COG0583	DNA-binding transcription factor activity
CAY59_RS24540	COG4628	conserved protein (DUF2132)
CAY59_RS24550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CAY59_RS24565	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CAY59_RS24570	COG0628	permease
CAY59_RS24610	COG2988	succinylglutamate desuccinylase activity
CAY59_RS24620	COG2814	Major facilitator Superfamily
CAY59_RS24630	COG0454	-acetyltransferase
CAY59_RS24640	COG0745	RESPONSE REGULATOR receiver
CAY59_RS24645	COG2205	protein histidine kinase activity
CAY59_RS24660	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CAY59_RS24665	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CAY59_RS24670	COG1882	Formate acetyltransferase
CAY59_RS24710	COG0251	oxidation-reduction process
CAY59_RS24720	COG1294	oxidase, subunit
CAY59_RS24725	COG1271	oxidase subunit
CAY59_RS24740	COG3220	belongs to the UPF0276 family
CAY59_RS24755	COG0384	phenazine biosynthesis protein PhzF
CAY59_RS24760	COG0346	lactoylglutathione lyase activity
CAY59_RS24775	COG0488	(ABC) transporter
CAY59_RS24780	COG4628	conserved protein (DUF2132)
CAY59_RS24795	COG0583	DNA-binding transcription factor activity
CAY59_RS24805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CAY59_RS24810	COG1280	lysine exporter protein (LysE YggA)
CAY59_RS24840	COG0737	Belongs to the 5'-nucleotidase family
CAY59_RS24845	COG3537	Alpha-1,2-mannosidase
CAY59_RS24850	COG3537	Alpha-1,2-mannosidase
CAY59_RS24860	COG3537	Alpha-1,2-mannosidase
CAY59_RS24865	COG3537	Alpha-1,2-mannosidase
CAY59_RS24870	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CAY59_RS24880	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAY59_RS24880	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAY59_RS24885	COG0346	lactoylglutathione lyase activity
CAY59_RS24890	COG1349	DNA-binding transcription factor activity
CAY59_RS24905	COG0753	catalase activity
CAY59_RS24965	COG0583	DNA-binding transcription factor activity
CAY59_RS24970	COG0589	response to stress
CAY59_RS24975	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CAY59_RS24990	COG4175	Glycine betaine
CAY59_RS24990	COG3448	diguanylate cyclase activity
CAY59_RS24995	COG4176	ABC-type proline glycine betaine transport system permease component
CAY59_RS25005	COG1342	Belongs to the UPF0251 family
CAY59_RS25035	COG4948	Mandelate Racemase Muconate Lactonizing
CAY59_RS25075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAY59_RS25085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAY59_RS25095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAY59_RS25105	COG1309	transcriptional regulator
CAY59_RS25115	COG0318	PFAM AMP-dependent synthetase and ligase
CAY59_RS25120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CAY59_RS25150	COG0786	glutamate:sodium symporter activity
CAY59_RS25155	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CAY59_RS25170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAY59_RS25175	COG0583	DNA-binding transcription factor activity
CAY59_RS25210	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CAY59_RS25215	COG2197	response regulator
CAY59_RS25235	COG0252	asparaginase activity
CAY59_RS25250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CAY59_RS25255	COG0583	DNA-binding transcription factor activity
CAY59_RS25265	COG2321	neutral zinc metallopeptidase
CAY59_RS25270	COG3122	Protein conserved in bacteria
CAY59_RS25285	COG2255	four-way junction helicase activity
CAY59_RS25295	COG3853	Toxic anion resistance protein (TelA)
CAY59_RS25305	COG1902	pentaerythritol trinitrate reductase activity
CAY59_RS25325	COG0583	DNA-binding transcription factor activity
CAY59_RS25335	COG0513	Belongs to the DEAD box helicase family
CAY59_RS25380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAY59_RS25405	COG3746	phosphate-selective porin O and P
CAY59_RS25435	COG1028	Short-chain dehydrogenase reductase Sdr
CAY59_RS25480	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CAY59_RS25490	COG0625	glutathione transferase activity
CAY59_RS25495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CAY59_RS25500	COG1686	Belongs to the peptidase S11 family
CAY59_RS25510	COG2226	methyltransferase
CAY59_RS25540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CAY59_RS25555	COG1278	Cold shock
CAY59_RS25560	COG1741	Belongs to the pirin family
CAY59_RS25565	COG4667	esterase of the alpha-beta hydrolase superfamily
CAY59_RS25575	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CAY59_RS25585	COG0523	cobalamin synthesis protein
CAY59_RS25610	COG3842	ATPase activity
CAY59_RS25615	COG0395	ABC-type sugar transport system, permease component
CAY59_RS25620	COG1175	transmembrane transport
CAY59_RS25640	COG0589	response to stress
CAY59_RS25650	COG0488	(ABC) transporter
CAY59_RS25655	COG1505	serine-type exopeptidase activity
CAY59_RS25665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAY59_RS25675	COG2067	long-chain fatty acid transport protein
CAY59_RS25685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAY59_RS25695	COG1858	cytochrome C peroxidase
CAY59_RS25710	COG0494	nUDIX hydrolase
CAY59_RS25755	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAY59_RS25780	COG3383	formate dehydrogenase (NAD+) activity
CAY59_RS25800	COG0842	Transport permease protein
CAY59_RS25805	COG1131	(ABC) transporter
CAY59_RS25815	COG0840	transmembrane signaling receptor activity
CAY59_RS25830	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CAY59_RS25840	COG4145	pantothenate transmembrane transporter activity
CAY59_RS25845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAY59_RS25850	COG0800	Aldolase
CAY59_RS25860	COG2706	6-phosphogluconolactonase activity
CAY59_RS25875	COG1881	PFAM PEBP family protein
CAY59_RS25890	COG0798	PFAM Bile acid sodium symporter
CAY59_RS25905	COG1733	regulation of RNA biosynthetic process
CAY59_RS25915	COG0747	negative chemotaxis
CAY59_RS25920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAY59_RS25925	COG2213	PTS system mannitol-specific
CAY59_RS25930	COG1063	alcohol dehydrogenase
CAY59_RS25945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CAY59_RS25965	COG0814	amino acid
CAY59_RS25980	COG3314	Sporulation integral membrane protein YlbJ
CAY59_RS26000	COG0739	heme binding
CAY59_RS26010	COG0583	DNA-binding transcription factor activity
CAY59_RS26015	COG2814	Major facilitator Superfamily
CAY59_RS26035	COG0697	spore germination
CAY59_RS26050	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAY59_RS26070	COG1280	lysine exporter protein (LysE YggA)
CAY59_RS26080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CAY59_RS26090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CAY59_RS26095	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CAY59_RS26120	COG1612	heme a metabolic process
CAY59_RS26135	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CAY59_RS26140	COG2814	Major facilitator Superfamily
CAY59_RS26150	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CAY59_RS26185	COG2897	thiosulfate sulfurtransferase activity
CAY59_RS26240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CAY59_RS26245	COG0303	'Molybdopterin
CAY59_RS26260	COG1914	H( )-stimulated, divalent metal cation uptake system
CAY59_RS26285	COG4989	oxidoreductase activity
CAY59_RS26300	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CAY59_RS26300	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CAY59_RS26320	COG1073	alpha beta
CAY59_RS26330	COG0583	DNA-binding transcription factor activity
CAY59_RS26360	COG0455	bacterial-type flagellum organization
CAY59_RS26400	COG2885	chlorophyll binding
CAY59_RS26420	COG0402	S-adenosylhomocysteine deaminase activity
CAY59_RS26430	COG3706	GGDEF domain
CAY59_RS26455	COG4176	ABC-type proline glycine betaine transport system permease component
CAY59_RS26470	COG0330	HflC and HflK could
CAY59_RS26500	COG2205	protein histidine kinase activity
CAY59_RS26500	COG0784	Response regulator, receiver
CAY59_RS26545	COG0586	Pfam SNARE associated Golgi protein
CAY59_RS26570	COG1051	belongs to the nudix hydrolase family
CAY59_RS26575	COG1794	racemase activity, acting on amino acids and derivatives
CAY59_RS26585	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CAY59_RS26590	COG5001	Diguanylate cyclase
CAY59_RS26600	COG1129	ABC transporter
CAY59_RS26605	COG1172	Belongs to the binding-protein-dependent transport system permease family
CAY59_RS26610	COG1879	ABC-type sugar transport system periplasmic component
CAY59_RS26615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAY59_RS26620	COG1609	Transcriptional regulator
CAY59_RS26635	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CAY59_RS26650	COG4607	ABC-type enterochelin transport system periplasmic component
CAY59_RS26655	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAY59_RS26660	COG4605	iron ion homeostasis
CAY59_RS26665	COG4604	ABC transporter, ATP-binding protein
CAY59_RS26670	COG0789	Transcriptional regulator
CAY59_RS26695	COG1289	transmembrane transporter activity
CAY59_RS26700	COG0210	DNA helicase
CAY59_RS26710	COG1879	ABC-type sugar transport system periplasmic component
CAY59_RS26715	COG2198	Histidine kinase
CAY59_RS26715	COG0784	Response regulator, receiver
CAY59_RS26715	COG2205	protein histidine kinase activity
CAY59_RS26745	COG3119	arylsulfatase activity
CAY59_RS26750	COG3119	arylsulfatase activity
CAY59_RS26755	COG3063	Type IV pilus biogenesis stability protein PilW
CAY59_RS26760	COG0714	Associated with various cellular activities
CAY59_RS26820	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CAY59_RS26830	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CAY59_RS26840	COG0583	DNA-binding transcription factor activity
CAY59_RS26845	COG1597	lipid kinase activity
CAY59_RS26850	COG3111	PFAM Bacterial OB fold (BOF) protein
CAY59_RS26870	COG0641	radical SAM
CAY59_RS26895	COG0501	Belongs to the peptidase M48B family
CAY59_RS26900	COG1704	LemA family
CAY59_RS26905	COG3069	C4-dicarboxylate transmembrane transporter activity
CAY59_RS26935	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CAY59_RS26940	COG0739	heme binding
CAY59_RS26975	COG2081	HI0933 family
CAY59_RS27090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CAY59_RS27115	COG3015	lipoprotein NlpE involved in copper resistance
CAY59_RS27190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CAY59_RS27385	COG1192	Involved in chromosome partitioning
CAY59_RS27430	COG2003	Belongs to the UPF0758 family
CAY59_RS27455	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CAY59_RS27475	COG3501	Rhs element vgr protein
CAY59_RS27490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CAY59_RS27795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CAY59_RS27830	COG3504	Conjugal transfer protein
CAY59_RS27845	COG4962	Type ii secretion system protein e
CAY59_RS27855	COG3451	type IV secretory pathway VirB4
CAY59_RS27860	COG5268	conjugation
CAY59_RS27905	COG1192	Involved in chromosome partitioning
CAY59_RS27930	COG0419	ATPase involved in DNA repair
CAY59_RS28050	COG5492	domain, Protein
CAY59_RS28050	COG4932	domain protein
CAY59_RS28095	COG1192	Involved in chromosome partitioning
CAY59_RS28200	COG0739	heme binding
CAY59_RS28210	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CAY59_RS28240	COG5492	domain, Protein
CAY59_RS28240	COG4932	domain protein
CAY59_RS28265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CAY59_RS28270	COG4974	Belongs to the 'phage' integrase family
CAY59_RS28280	COG2337	Toxic component of a toxin-antitoxin (TA) module
CAY59_RS28335	COG2885	chlorophyll binding
CAY59_RS28400	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CAY59_RS28415	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CAY59_RS28520	COG3451	type IV secretory pathway VirB4
CAY59_RS28535	COG3701	Conjugal transfer protein
CAY59_RS28550	COG2948	multi-organism process
CAY59_RS28570	COG2885	chlorophyll binding
CAY59_RS28570	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CAY59_RS28590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CAY59_RS28665	COG4962	Type ii secretion system protein e