locus-tag	class	description
HB763_RS00020	COG0123	including yeast histone deacetylase and acetoin utilization protein
HB763_RS00035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HB763_RS00040	COG0778	Nitroreductase
HB763_RS00045	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB763_RS00045	COG1902	pentaerythritol trinitrate reductase activity
HB763_RS00050	COG0616	signal peptide processing
HB763_RS00055	COG0252	asparaginase activity
HB763_RS00060	COG3139	Protein of unknown function (DUF1315)
HB763_RS00070	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB763_RS00075	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HB763_RS00095	COG2226	methyltransferase
HB763_RS00110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB763_RS00120	COG1785	Belongs to the alkaline phosphatase family
HB763_RS00140	COG0668	transmembrane transport
HB763_RS00145	COG0076	glutamate decarboxylase activity
HB763_RS00150	COG2985	domain, Protein
HB763_RS00155	COG2261	transglycosylase associated protein
HB763_RS00160	COG2983	Belongs to the UPF0260 family
HB763_RS00170	COG2964	Protein conserved in bacteria
HB763_RS00180	COG0251	oxidation-reduction process
HB763_RS00185	COG0814	amino acid
HB763_RS00190	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HB763_RS00215	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HB763_RS00225	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HB763_RS00235	COG2832	Protein of unknown function (DUF454)
HB763_RS00245	COG0745	RESPONSE REGULATOR receiver
HB763_RS00250	COG0583	DNA-binding transcription factor activity
HB763_RS00255	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HB763_RS00260	COG1286	toxin biosynthetic process
HB763_RS00265	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HB763_RS00270	COG0285	dihydrofolate synthase activity
HB763_RS00290	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HB763_RS00295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HB763_RS00300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HB763_RS00320	COG3101	peptidyl-lysine hydroxylation
HB763_RS00325	COG2860	membrane
HB763_RS00340	COG2890	protein-(glutamine-N5) methyltransferase activity
HB763_RS00350	COG2062	phosphohistidine phosphatase, SixA
HB763_RS00365	COG0183	Belongs to the thiolase family
HB763_RS00380	COG2067	long-chain fatty acid transport protein
HB763_RS00385	COG2067	long-chain fatty acid transport protein
HB763_RS00390	COG2853	Lipoprotein
HB763_RS00395	COG3088	subunit of a heme lyase
HB763_RS00395	COG4235	cytochrome complex assembly
HB763_RS00405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HB763_RS00410	COG1138	Cytochrome C-type biogenesis protein
HB763_RS00425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HB763_RS00430	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HB763_RS00435	COG4133	protoheme IX ABC transporter activity
HB763_RS00445	COG0835	chemotaxis
HB763_RS00455	COG1192	Involved in chromosome partitioning
HB763_RS00460	COG2201	protein-glutamate methylesterase activity
HB763_RS00465	COG2198	Histidine kinase
HB763_RS00465	COG0784	Response regulator, receiver
HB763_RS00465	COG0643	Histidine kinase
HB763_RS00470	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HB763_RS00505	COG1684	flagellar biosynthetic protein fliR
HB763_RS00510	COG1987	bacterial-type flagellum assembly
HB763_RS00565	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HB763_RS00575	COG1677	Flagellar hook-basal body complex protein FliE
HB763_RS00595	COG1516	flagellar protein fliS
HB763_RS00605	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HB763_RS00610	COG1334	flagellar protein FlaG
HB763_RS00615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_RS00620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_RS00625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_RS00630	COG2837	iron assimilation
HB763_RS00655	COG1393	Belongs to the ArsC family
HB763_RS00675	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HB763_RS00680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HB763_RS00685	COG2716	regulation of RNA biosynthetic process
HB763_RS00715	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HB763_RS00750	COG0515	serine threonine protein kinase
HB763_RS00750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HB763_RS00755	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HB763_RS00770	COG3501	Rhs element vgr protein
HB763_RS00805	COG3335	DDE superfamily endonuclease
HB763_RS00815	COG3344	reverse transcriptase
HB763_RS00865	COG4783	chaperone-mediated protein folding
HB763_RS00870	COG1393	Belongs to the ArsC family
HB763_RS00890	COG2233	PERMEase
HB763_RS00895	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HB763_RS00900	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HB763_RS00905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HB763_RS00910	COG0121	glutamine amidotransferase
HB763_RS00915	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HB763_RS00920	COG1960	acyl-CoA dehydrogenase activity
HB763_RS00940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HB763_RS00950	COG2226	methyltransferase
HB763_RS00960	COG0741	lytic transglycosylase activity
HB763_RS00960	COG1388	LysM domain
HB763_RS00975	COG0347	Belongs to the P(II) protein family
HB763_RS00995	COG0587	DNA-directed DNA polymerase activity
HB763_RS01020	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HB763_RS01025	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HB763_RS01035	COG0750	zinc metalloprotease
HB763_RS01045	COG0575	Belongs to the CDS family
HB763_RS01050	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HB763_RS01075	COG0024	Methionine aminopeptidase
HB763_RS01090	COG0564	pseudouridine synthase activity
HB763_RS01095	COG3098	single-species biofilm formation
HB763_RS01125	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HB763_RS01140	COG1720	tRNA m6t6A37 methyltransferase activity
HB763_RS01165	COG0733	neurotransmitter:sodium symporter activity
HB763_RS01180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB763_RS01185	COG0514	ATP-dependent DNA helicase (RecQ)
HB763_RS01190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HB763_RS01205	COG1477	protein flavinylation
HB763_RS01215	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB763_RS01220	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB763_RS01230	COG1805	sodium ion transport
HB763_RS01235	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HB763_RS01240	COG0271	Belongs to the BolA IbaG family
HB763_RS01270	COG1595	DNA-templated transcription, initiation
HB763_RS01285	COG3248	Nucleoside-binding outer membrane protein
HB763_RS01290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HB763_RS01295	COG0693	protein deglycase activity
HB763_RS01300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HB763_RS01305	COG2166	iron-sulfur cluster assembly
HB763_RS01310	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HB763_RS01315	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HB763_RS01325	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HB763_RS01325	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HB763_RS01335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HB763_RS01340	COG1074	ATP-dependent DNA helicase activity
HB763_RS01345	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HB763_RS01370	COG3141	response to X-ray
HB763_RS01385	COG2171	N-acyltransferase activity
HB763_RS01390	COG0584	glycerophosphoryl diester phosphodiesterase
HB763_RS01395	COG2271	Major facilitator Superfamily
HB763_RS01400	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HB763_RS01410	COG1349	DNA-binding transcription factor activity
HB763_RS01415	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HB763_RS01440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HB763_RS01445	COG0768	penicillin binding
HB763_RS01450	COG1609	Transcriptional regulator
HB763_RS01455	COG0583	DNA-binding transcription factor activity
HB763_RS01470	COG1022	Amp-dependent synthetase and ligase
HB763_RS01475	COG3385	transposase activity
HB763_RS01505	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HB763_RS01510	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HB763_RS01520	COG0560	Phosphoserine phosphatase
HB763_RS01530	COG0813	purine-nucleoside phosphorylase activity
HB763_RS01540	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HB763_RS01550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB763_RS01555	COG0084	hydrolase, TatD family'
HB763_RS01585	COG3153	acetyltransferase
HB763_RS01590	COG3154	lipid carrier protein
HB763_RS01600	COG0826	peptidase U32
HB763_RS01605	COG0826	peptidase U32
HB763_RS01610	COG0534	Mate efflux family protein
HB763_RS01630	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HB763_RS01650	COG0195	Participates in both transcription termination and antitermination
HB763_RS01670	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HB763_RS01680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HB763_RS01685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HB763_RS01695	COG1534	Rna-binding protein
HB763_RS01700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB763_RS01705	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HB763_RS01710	COG2027	D-alanyl-D-alanine carboxypeptidase
HB763_RS01725	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HB763_RS01730	COG0739	heme binding
HB763_RS01735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB763_RS01755	COG0628	permease
HB763_RS01765	COG0784	Response regulator, receiver
HB763_RS01765	COG2198	Histidine kinase
HB763_RS01765	COG2205	protein histidine kinase activity
HB763_RS01765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB763_RS01770	COG0747	negative chemotaxis
HB763_RS01780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB763_RS01785	COG0444	Belongs to the ABC transporter superfamily
HB763_RS01790	COG4608	Belongs to the ABC transporter superfamily
HB763_RS01800	COG2971	BadF BadG BcrA BcrD
HB763_RS01815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HB763_RS01820	COG3842	ATPase activity
HB763_RS01830	COG1840	ABC-type Fe3 transport system, periplasmic component
HB763_RS01835	COG0004	ammonium transporteR
HB763_RS01850	COG1049	propionate catabolic process, 2-methylcitrate cycle
HB763_RS01855	COG1752	Esterase of the alpha-beta hydrolase superfamily
HB763_RS01860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HB763_RS01865	COG1643	Atp-dependent helicase
HB763_RS01880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HB763_RS01890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HB763_RS01910	COG0842	Transport permease protein
HB763_RS01915	COG1131	(ABC) transporter
HB763_RS01920	COG0659	secondary active sulfate transmembrane transporter activity
HB763_RS01925	COG0288	reversible hydration of carbon dioxide
HB763_RS01940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB763_RS01945	COG0508	dehydrogenase complex catalyzes the overall conversion of
HB763_RS01950	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HB763_RS01955	COG2186	Transcriptional regulator
HB763_RS01975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB763_RS01980	COG1459	type II secretion system
HB763_RS01990	COG0237	dephospho-CoA kinase activity
HB763_RS01995	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HB763_RS02000	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HB763_RS02020	COG0228	four-way junction DNA binding
HB763_RS02025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HB763_RS02030	COG4137	Cytochrome C assembly protein
HB763_RS02035	COG4536	flavin adenine dinucleotide binding
HB763_RS02055	COG0612	Peptidase, M16
HB763_RS02060	COG1238	metal cluster binding
HB763_RS02070	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HB763_RS02075	COG0511	ligase activity, forming carbon-carbon bonds
HB763_RS02075	COG5016	pyruvate
HB763_RS02080	COG3630	sodium ion export across plasma membrane
HB763_RS02085	COG3335	DDE superfamily endonuclease
HB763_RS02175	COG0527	aspartate kinase activity
HB763_RS02190	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HB763_RS02195	COG1546	Belongs to the CinA family
HB763_RS02205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HB763_RS02235	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HB763_RS02245	COG0148	phosphopyruvate hydratase activity
HB763_RS02255	COG3956	TIGRFAM MazG family protein
HB763_RS02260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HB763_RS02280	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HB763_RS02285	COG1381	Involved in DNA repair and RecF pathway recombination
HB763_RS02290	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HB763_RS02310	COG3086	response to oxidative stress
HB763_RS02325	COG1595	DNA-templated transcription, initiation
HB763_RS02330	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HB763_RS02340	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HB763_RS02360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB763_RS02365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB763_RS02375	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HB763_RS02385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HB763_RS02395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HB763_RS02420	COG0668	transmembrane transport
HB763_RS02425	COG0191	fructose-bisphosphate aldolase activity
HB763_RS02445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HB763_RS02465	COG2356	endonuclease I
HB763_RS02470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HB763_RS02475	COG0189	ligase activity
HB763_RS02480	COG1678	Uncharacterized ACR, COG1678
HB763_RS02485	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HB763_RS02500	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HB763_RS02505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HB763_RS02510	COG0762	integral membrane protein
HB763_RS02525	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HB763_RS02530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HB763_RS02630	COG1012	belongs to the aldehyde dehydrogenase family
HB763_RS02680	COG1609	Transcriptional regulator
HB763_RS02690	COG1486	melibiose metabolic process
HB763_RS02695	COG1447	Phosphotransferase system cellobiose-specific component IIA
HB763_RS02710	COG0726	polysaccharide deacetylase
HB763_RS02720	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_RS02730	COG0795	lipopolysaccharide-transporting ATPase activity
HB763_RS02735	COG0795	lipopolysaccharide-transporting ATPase activity
HB763_RS02745	COG2927	DNA polymerase III (CHI subunit)
HB763_RS02750	COG0525	valine-tRNA ligase activity
HB763_RS02760	COG0456	acetyltransferase
HB763_RS02795	COG0251	oxidation-reduction process
HB763_RS02800	COG0204	Acyl-transferase
HB763_RS02810	COG5007	Belongs to the BolA IbaG family
HB763_RS02820	COG2854	intermembrane phospholipid transfer
HB763_RS02825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HB763_RS02830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HB763_RS02835	COG1127	ABC transporter
HB763_RS02845	COG0517	IMP dehydrogenase activity
HB763_RS02845	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HB763_RS02855	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HB763_RS02860	COG1137	ATPase activity
HB763_RS02870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HB763_RS02875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB763_RS02885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB763_RS02890	COG2239	Acts as a magnesium transporter
HB763_RS02895	COG0312	modulator of DNA gyrase
HB763_RS02905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB763_RS02910	COG0564	pseudouridine synthase activity
HB763_RS02925	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HB763_RS02930	COG0312	modulator of DNA gyrase
HB763_RS02935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HB763_RS02940	COG3164	Protein of unknown function
HB763_RS02950	COG0424	maF-like protein
HB763_RS02955	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HB763_RS02960	COG1792	Involved in formation and maintenance of cell shape
HB763_RS02965	COG1077	Cell shape determining protein MreB Mrl
HB763_RS03000	COG2165	general secretion pathway protein
HB763_RS03010	COG1459	type II secretion system
HB763_RS03015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB763_RS03025	COG3409	Peptidoglycan-binding domain 1 protein
HB763_RS03025	COG3267	Type II secretory pathway component ExeA
HB763_RS03050	COG2199	diguanylate cyclase activity
HB763_RS03050	COG2200	EAL domain
HB763_RS03055	COG0629	single-stranded DNA binding
HB763_RS03070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HB763_RS03080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HB763_RS03085	COG0527	aspartate kinase activity
HB763_RS03090	COG0646	methionine synthase
HB763_RS03090	COG1410	methionine synthase
HB763_RS03155	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HB763_RS03175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB763_RS03180	COG0735	belongs to the Fur family
HB763_RS03195	COG0432	Pfam Uncharacterised protein family UPF0047
HB763_RS03205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HB763_RS03210	COG0305	Participates in initiation and elongation during chromosome replication
HB763_RS03230	COG2965	DNA replication, synthesis of RNA primer
HB763_RS03240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HB763_RS03245	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HB763_RS03290	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HB763_RS03300	COG0678	peroxiredoxin activity
HB763_RS03300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HB763_RS03305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB763_RS03315	COG0165	Argininosuccinate lyase
HB763_RS03315	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HB763_RS03330	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HB763_RS03340	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HB763_RS03350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HB763_RS03355	COG0460	homoserine dehydrogenase
HB763_RS03355	COG0527	aspartate kinase activity
HB763_RS03360	COG0626	cystathionine gamma-synthase activity
HB763_RS03370	COG0281	malic enzyme
HB763_RS03380	COG2906	2 iron, 2 sulfur cluster binding
HB763_RS03390	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HB763_RS03405	COG2168	tRNA wobble position uridine thiolation
HB763_RS03410	COG2923	Belongs to the DsrF TusC family
HB763_RS03415	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HB763_RS03420	COG2964	Protein conserved in bacteria
HB763_RS03425	COG0545	Peptidyl-prolyl cis-trans isomerase
HB763_RS03440	COG1446	asparaginase
HB763_RS03445	COG1047	Peptidyl-prolyl cis-trans
HB763_RS03460	COG2249	NAD(P)H dehydrogenase (quinone) activity
HB763_RS03465	COG0488	(ABC) transporter
HB763_RS03475	COG0429	hydrolase of the alpha beta-hydrolase fold
HB763_RS03485	COG3954	Phosphoribulokinase
HB763_RS03490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB763_RS03510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HB763_RS03515	COG0512	Glutamine amidotransferase of anthranilate synthase
HB763_RS03535	COG0546	phosphoglycolate phosphatase activity
HB763_RS03540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB763_RS03545	COG0557	exoribonuclease II activity
HB763_RS03555	COG1017	nitric oxide dioxygenase activity
HB763_RS03555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB763_RS03560	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HB763_RS03565	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HB763_RS03570	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HB763_RS03575	COG0330	HflC and HflK could
HB763_RS03580	COG0330	HflC and HflK could
HB763_RS03585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HB763_RS03600	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HB763_RS03605	COG0860	N-Acetylmuramoyl-L-alanine amidase
HB763_RS03610	COG0802	atpase or kinase
HB763_RS03615	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HB763_RS03685	COG1162	GTPase activity
HB763_RS03695	COG0471	metal ion transport
HB763_RS03710	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HB763_RS03715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HB763_RS03730	COG1045	serine acetyltransferase
HB763_RS03735	COG4942	peptidase
HB763_RS03760	COG1053	succinate dehydrogenase
HB763_RS03765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HB763_RS03795	COG1509	lysine 2,3-aminomutase activity
HB763_RS03820	COG0534	Mate efflux family protein
HB763_RS03830	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HB763_RS03840	COG0745	RESPONSE REGULATOR receiver
HB763_RS03845	COG2205	protein histidine kinase activity
HB763_RS03910	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HB763_RS03915	COG0732	type I restriction modification DNA specificity domain
HB763_RS03920	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HB763_RS03950	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HB763_RS03955	COG1074	ATP-dependent DNA helicase activity
HB763_RS03960	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HB763_RS03965	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HB763_RS03970	COG3030	protein affecting phage T7 exclusion by the F plasmid
HB763_RS03975	COG1027	Aspartate ammonia-lyase
HB763_RS03980	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HB763_RS03985	COG4232	protein-disulfide reductase activity
HB763_RS03995	COG2095	MarC family integral membrane protein
HB763_RS04005	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HB763_RS04025	COG2205	protein histidine kinase activity
HB763_RS04025	COG0784	Response regulator, receiver
HB763_RS04025	COG2198	Histidine kinase
HB763_RS04030	COG2814	Major facilitator Superfamily
HB763_RS04045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HB763_RS04050	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HB763_RS04055	COG0511	ligase activity, forming carbon-carbon bonds
HB763_RS04060	COG0439	Biotin carboxylase
HB763_RS04070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB763_RS04075	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HB763_RS04080	COG2199	diguanylate cyclase activity
HB763_RS04125	COG1982	Orn Lys Arg decarboxylase major
HB763_RS04130	COG0531	amino acid
HB763_RS04135	COG3710	Transcriptional regulator
HB763_RS04140	COG0789	Transcriptional regulator
HB763_RS04150	COG0151	Belongs to the GarS family
HB763_RS04165	COG1253	flavin adenine dinucleotide binding
HB763_RS04170	COG3068	Protein conserved in bacteria
HB763_RS04180	COG1573	uracil-dna glycosylase
HB763_RS04190	COG2816	NAD+ diphosphatase activity
HB763_RS04195	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HB763_RS04215	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HB763_RS04230	COG0250	Participates in transcription elongation, termination and antitermination
HB763_RS04235	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HB763_RS04275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HB763_RS04285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HB763_RS04385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB763_RS04390	COG0534	Mate efflux family protein
HB763_RS04405	COG2937	Belongs to the GPAT DAPAT family
HB763_RS04415	COG3161	chorismate lyase activity
HB763_RS04420	COG1580	Controls the rotational direction of flagella during chemotaxis
HB763_RS04425	COG0705	Rhomboid family
HB763_RS04440	COG2177	Part of the ABC transporter FtsEX involved in
HB763_RS04445	COG2884	Cell division ATP-binding protein ftsE
HB763_RS04450	COG0552	protein localization to endoplasmic reticulum
HB763_RS04455	COG0742	ribosomal rna small subunit methyltransferase
HB763_RS04465	COG2095	MarC family integral membrane protein
HB763_RS04510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HB763_RS04515	COG0640	Transcriptional regulator
HB763_RS04520	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HB763_RS04525	COG1280	lysine exporter protein (LysE YggA)
HB763_RS04530	COG2267	carboxylic ester hydrolase activity
HB763_RS04535	COG0561	phosphatase activity
HB763_RS04550	COG3148	PFAM DTW domain containing protein
HB763_RS04555	COG2199	diguanylate cyclase activity
HB763_RS04555	COG2200	EAL domain
HB763_RS04555	COG3287	FIST C domain
HB763_RS04560	COG1011	Hydrolase
HB763_RS04580	COG0019	diaminopimelate decarboxylase activity
HB763_RS04595	COG3072	Adenylate cyclase
HB763_RS04605	COG1587	Uroporphyrinogen-III synthase
HB763_RS04610	COG2959	enzyme of heme biosynthesis
HB763_RS04615	COG3071	HemY protein
HB763_RS04655	COG0633	Ferredoxin
HB763_RS04660	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HB763_RS04675	COG3118	belongs to the thioredoxin family
HB763_RS04690	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HB763_RS04700	COG0514	ATP-dependent DNA helicase (RecQ)
HB763_RS04705	COG2962	Rard protein
HB763_RS04715	COG1280	lysine exporter protein (LysE YggA)
HB763_RS04720	COG0405	Gamma-glutamyltransferase
HB763_RS04725	COG0210	DNA helicase
HB763_RS04735	COG3220	belongs to the UPF0276 family
HB763_RS04755	COG2814	Major facilitator Superfamily
HB763_RS04765	COG0006	proline dipeptidase activity
HB763_RS04765	COG0006	proline dipeptidase activity
HB763_RS04780	COG2104	thiamine diphosphate biosynthetic process
HB763_RS04785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HB763_RS04805	COG2132	Multicopper oxidase
HB763_RS04855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB763_RS04860	COG1739	Uncharacterized protein family UPF0029
HB763_RS04870	COG0183	Belongs to the thiolase family
HB763_RS04875	COG0604	alcohol dehydrogenase
HB763_RS04900	COG2119	membrane
HB763_RS04915	COG3977	Valine--pyruvate aminotransferase
HB763_RS04920	COG0071	Belongs to the small heat shock protein (HSP20) family
HB763_RS04925	COG0187	DNA topoisomerase II activity
HB763_RS04935	COG0592	DNA-directed DNA polymerase activity
HB763_RS04955	COG1126	abc transporter atp-binding protein
HB763_RS04985	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HB763_RS05000	COG1192	Involved in chromosome partitioning
HB763_RS05005	COG1475	DNA binding
HB763_RS05010	COG3312	ion transport
HB763_RS05040	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HB763_RS05050	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HB763_RS05060	COG0765	amino acid transport
HB763_RS05065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB763_RS05070	COG2814	Major facilitator Superfamily
HB763_RS05075	COG0583	DNA-binding transcription factor activity
HB763_RS05085	COG0129	dihydroxy-acid dehydratase activity
HB763_RS05090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HB763_RS05095	COG3978	acetolactate synthase activity
HB763_RS05105	COG0606	chelatase, subunit chli
HB763_RS05110	COG2199	diguanylate cyclase activity
HB763_RS05120	COG0204	Acyl-transferase
HB763_RS05125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB763_RS05130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HB763_RS05140	COG3084	Protein conserved in bacteria
HB763_RS05150	COG4326	sporulation control protein
HB763_RS05155	COG1272	protein, Hemolysin III
HB763_RS05165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB763_RS05170	COG0569	domain protein
HB763_RS05175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HB763_RS05175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HB763_RS05195	COG0758	DNA mediated transformation
HB763_RS05205	COG0551	DNA topoisomerase type I activity
HB763_RS05210	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HB763_RS05215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HB763_RS05240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HB763_RS05280	COG0583	DNA-binding transcription factor activity
HB763_RS05285	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HB763_RS05290	COG2960	long-chain fatty acid transporting porin activity
HB763_RS05295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB763_RS05300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB763_RS05345	COG0546	phosphoglycolate phosphatase activity
HB763_RS05350	COG4172	Belongs to the ABC transporter superfamily
HB763_RS05355	COG4166	transmembrane transport
HB763_RS05360	COG0601	transmembrane transport
HB763_RS05365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB763_RS05410	COG0800	Aldolase
HB763_RS05415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HB763_RS05425	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HB763_RS05435	COG1522	sequence-specific DNA binding
HB763_RS05440	COG5001	Diguanylate cyclase
HB763_RS05440	COG5002	protein histidine kinase activity
HB763_RS05460	COG0589	response to stress
HB763_RS05465	COG1528	Iron-storage protein
HB763_RS05475	COG2081	HI0933 family
HB763_RS05495	COG1910	domain protein
HB763_RS05510	COG1322	Protein conserved in bacteria
HB763_RS05520	COG3165	ubiquinone biosynthetic process from chorismate
HB763_RS05535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HB763_RS05540	COG0805	protein transport
HB763_RS05545	COG0084	hydrolase, TatD family'
HB763_RS05560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HB763_RS05560	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HB763_RS05565	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HB763_RS05595	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HB763_RS05605	COG2204	response regulator
HB763_RS05610	COG3852	Histidine kinase
HB763_RS05620	COG0174	glutamine synthetase
HB763_RS05625	COG1217	gtp-binding protein TYPA
HB763_RS05645	COG1490	D-aminoacyl-tRNA deacylase activity
HB763_RS05650	COG0456	acetyltransferase
HB763_RS05670	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HB763_RS05675	COG3031	protein transport across the cell outer membrane
HB763_RS05685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB763_RS05690	COG1459	type II secretion system
HB763_RS05695	COG2165	general secretion pathway protein
HB763_RS05700	COG2165	general secretion pathway protein
HB763_RS05705	COG2165	general secretion pathway protein
HB763_RS05710	COG4795	General secretion pathway protein
HB763_RS05715	COG3156	type II secretion system protein K
HB763_RS05720	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HB763_RS05725	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HB763_RS05735	COG1218	3'(2'),5'-bisphosphate nucleotidase
HB763_RS05740	COG0494	nUDIX hydrolase
HB763_RS05750	COG1040	competence protein
HB763_RS05765	COG2183	response to ionizing radiation
HB763_RS05775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB763_RS05790	COG2233	PERMEase
HB763_RS05800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HB763_RS05805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB763_RS05810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HB763_RS05815	COG1758	RNA polymerase activity
HB763_RS05820	COG0194	GDP metabolic process
HB763_RS05835	COG0848	biopolymer transport protein
HB763_RS05840	COG0811	peptide transport
HB763_RS05860	COG4174	ABC transporter (Permease)
HB763_RS05865	COG4239	(ABC) transporter, permease
HB763_RS05870	COG0747	negative chemotaxis
HB763_RS05875	COG0444	Belongs to the ABC transporter superfamily
HB763_RS05880	COG4608	Belongs to the ABC transporter superfamily
HB763_RS05890	COG1561	YicC-like family, N-terminal region
HB763_RS05895	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HB763_RS05900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HB763_RS05905	COG1560	Kdo2-lipid A biosynthetic process
HB763_RS05915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HB763_RS05955	COG1404	Belongs to the peptidase S8 family
HB763_RS05980	COG4372	Transposase
HB763_RS06000	COG2194	sulfuric ester hydrolase activity
HB763_RS06020	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HB763_RS06035	COG0463	Glycosyl transferase, family 2
HB763_RS06040	COG0859	PFAM glycosyl transferase family 9
HB763_RS06045	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HB763_RS06050	COG3642	lipopolysaccharide core region biosynthetic process
HB763_RS06065	COG1519	Transferase
HB763_RS06070	COG0859	PFAM glycosyl transferase family 9
HB763_RS06080	COG1560	Kdo2-lipid A biosynthetic process
HB763_RS06090	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB763_RS06120	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HB763_RS06130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HB763_RS06140	COG2089	acid synthase
HB763_RS06150	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HB763_RS06175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HB763_RS06190	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HB763_RS06195	COG0149	triose-phosphate isomerase activity
HB763_RS06225	COG1494	fructose-1,6-bisphosphatase
HB763_RS06235	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB763_RS06240	COG1575	Belongs to the MenA family. Type 1 subfamily
HB763_RS06260	COG1609	Transcriptional regulator
HB763_RS06265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HB763_RS06285	COG0088	Forms part of the polypeptide exit tunnel
HB763_RS06370	COG1841	ribosomal large subunit assembly
HB763_RS06380	COG0201	protein transport
HB763_RS06385	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HB763_RS06390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HB763_RS06395	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HB763_RS06405	COG0202	RNA polymerase activity
HB763_RS06410	COG0203	ribosomal protein L17
HB763_RS06420	COG0545	Peptidyl-prolyl cis-trans isomerase
HB763_RS06450	COG2153	protein acetylation
HB763_RS06455	COG0513	Belongs to the DEAD box helicase family
HB763_RS06465	COG0737	Belongs to the 5'-nucleotidase family
HB763_RS06470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HB763_RS06470	COG1648	precorrin-2 dehydrogenase activity
HB763_RS06485	COG0471	metal ion transport
HB763_RS06485	COG3273	potassium ion transport
HB763_RS06490	COG0529	Catalyzes the synthesis of activated sulfate
HB763_RS06510	COG1136	(ABC) transporter
HB763_RS06525	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HB763_RS06535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB763_RS06550	COG2105	PFAM AIG2 family protein
HB763_RS06560	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HB763_RS06570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HB763_RS06575	COG0163	prenyltransferase activity
HB763_RS06580	COG4143	(ABC) transporter
HB763_RS06585	COG1178	ABC-type Fe3 transport system permease component
HB763_RS06590	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HB763_RS06605	COG2358	TRAP transporter, solute receptor (TAXI family
HB763_RS06625	COG0142	geranyltranstransferase activity
HB763_RS06630	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HB763_RS06645	COG2966	Psort location CytoplasmicMembrane, score
HB763_RS06650	COG3610	response to peptide
HB763_RS06655	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HB763_RS06675	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HB763_RS06680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB763_RS06685	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HB763_RS06690	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HB763_RS06710	COG0473	3-isopropylmalate dehydrogenase activity
HB763_RS06715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HB763_RS06735	COG0583	DNA-binding transcription factor activity
HB763_RS06740	COG1022	Amp-dependent synthetase and ligase
HB763_RS06745	COG0028	Belongs to the TPP enzyme family
HB763_RS06750	COG0440	acetolactate synthase activity
HB763_RS06755	COG3706	GGDEF domain
HB763_RS06765	COG0469	pyruvate kinase activity
HB763_RS06770	COG1349	DNA-binding transcription factor activity
HB763_RS06775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HB763_RS06825	COG0358	DNA primase activity
HB763_RS06830	COG1610	YqeY-like protein
HB763_RS06835	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HB763_RS06840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HB763_RS06845	COG0596	Alpha beta hydrolase
HB763_RS06855	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HB763_RS06860	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HB763_RS06875	COG3409	Peptidoglycan-binding domain 1 protein
HB763_RS06875	COG3267	Type II secretory pathway component ExeA
HB763_RS06885	COG0405	Gamma-glutamyltransferase
HB763_RS06890	COG4991	sh3 domain protein
HB763_RS06895	COG0306	phosphate transporter
HB763_RS06900	COG1392	Phosphate transport regulator
HB763_RS06905	COG3025	triphosphatase activity
HB763_RS06910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HB763_RS06920	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HB763_RS06930	COG1538	Outer membrane efflux protein
HB763_RS06935	COG0494	nUDIX hydrolase
HB763_RS06940	COG3151	Protein conserved in bacteria
HB763_RS06950	COG3150	esterase
HB763_RS06960	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HB763_RS06965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB763_RS06970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB763_RS06975	COG3105	Protein conserved in bacteria
HB763_RS06980	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HB763_RS06995	COG0723	plastoquinol--plastocyanin reductase activity
HB763_RS07000	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HB763_RS07005	COG2857	Cytochrome c1
HB763_RS07010	COG0625	glutathione transferase activity
HB763_RS07015	COG2969	positive regulation of protein catabolic process
HB763_RS07020	COG2823	Periplasmic or secreted lipoprotein
HB763_RS07025	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HB763_RS07040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HB763_RS07055	COG3116	cell division
HB763_RS07060	COG0768	penicillin binding
HB763_RS07065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HB763_RS07070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HB763_RS07085	COG0772	Belongs to the SEDS family
HB763_RS07100	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HB763_RS07105	COG0849	cell division
HB763_RS07110	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HB763_RS07130	COG0494	nUDIX hydrolase
HB763_RS07140	COG0505	Belongs to the CarA family
HB763_RS07145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HB763_RS07150	COG0730	response to heat
HB763_RS07155	COG0583	DNA-binding transcription factor activity
HB763_RS07160	COG2860	membrane
HB763_RS07185	COG0493	'glutamate synthase
HB763_RS07190	COG0067	glutamate synthase
HB763_RS07190	COG0069	glutamate synthase activity
HB763_RS07190	COG0070	glutamate synthase
HB763_RS07200	COG0070	glutamate synthase
HB763_RS07200	COG0067	glutamate synthase
HB763_RS07200	COG0069	glutamate synthase activity
HB763_RS07205	COG1242	4 iron, 4 sulfur cluster binding
HB763_RS07210	COG3706	GGDEF domain
HB763_RS07210	COG4251	negative regulation of phosphorylation
HB763_RS07210	COG5001	Diguanylate cyclase
HB763_RS07210	COG2203	Gaf domain
HB763_RS07215	COG0784	Response regulator, receiver
HB763_RS07215	COG2198	Histidine kinase
HB763_RS07215	COG5002	protein histidine kinase activity
HB763_RS07225	COG0745	RESPONSE REGULATOR receiver
HB763_RS07235	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB763_RS07250	COG0083	homoserine kinase activity
HB763_RS07255	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HB763_RS07260	COG0431	NADPH-dependent FMN reductase
HB763_RS07285	COG1115	amino acid carrier protein
HB763_RS07290	COG3022	response to hydroperoxide
HB763_RS07300	COG0513	Belongs to the DEAD box helicase family
HB763_RS07315	COG0716	FMN binding
HB763_RS07320	COG4974	Belongs to the 'phage' integrase family
HB763_RS07325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB763_RS07330	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HB763_RS07355	COG0667	Aldo Keto reductase
HB763_RS07380	COG0730	response to heat
HB763_RS07395	COG1283	sodium-dependent phosphate transmembrane transporter activity
HB763_RS07400	COG0583	DNA-binding transcription factor activity
HB763_RS07405	COG0640	Transcriptional regulator
HB763_RS07410	COG0268	Binds directly to 16S ribosomal RNA
HB763_RS07415	COG0728	peptidoglycan biosynthetic process
HB763_RS07420	COG0196	riboflavin kinase activity
HB763_RS07435	COG1047	Peptidyl-prolyl cis-trans
HB763_RS07440	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HB763_RS07445	COG3279	Response regulator of the LytR AlgR family
HB763_RS07450	COG3275	phosphorelay sensor kinase activity
HB763_RS07455	COG1966	Carbon starvation protein
HB763_RS07475	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HB763_RS07485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB763_RS07490	COG1605	Chorismate mutase
HB763_RS07490	COG0287	Prephenate dehydrogenase
HB763_RS07495	COG0739	heme binding
HB763_RS07505	COG0488	(ABC) transporter
HB763_RS07520	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HB763_RS07525	COG0077	Prephenate dehydratase
HB763_RS07525	COG1605	Chorismate mutase
HB763_RS07530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HB763_RS07535	COG0741	lytic transglycosylase activity
HB763_RS07540	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB763_RS07545	COG0564	pseudouridine synthase activity
HB763_RS07550	COG1496	oxidoreductase activity
HB763_RS07555	COG0542	response to heat
HB763_RS07610	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB763_RS07615	COG0826	peptidase U32
HB763_RS07625	COG0745	RESPONSE REGULATOR receiver
HB763_RS07630	COG5002	protein histidine kinase activity
HB763_RS07640	COG0248	Ppx GppA phosphatase
HB763_RS07645	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HB763_RS07650	COG0573	inorganic phosphate transmembrane transporter activity
HB763_RS07655	COG0581	inorganic phosphate transmembrane transporter activity
HB763_RS07660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HB763_RS07665	COG0704	Plays a role in the regulation of phosphate uptake
HB763_RS07680	COG0450	alkyl hydroperoxide reductase
HB763_RS07685	COG0583	DNA-binding transcription factor activity
HB763_RS07690	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HB763_RS07700	COG0517	IMP dehydrogenase activity
HB763_RS07720	COG1862	Preprotein translocase
HB763_RS07725	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB763_RS07730	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB763_RS07735	COG0483	inositol monophosphate 1-phosphatase activity
HB763_RS07740	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HB763_RS07755	COG0822	iron-sulfur transferase activity
HB763_RS07760	COG0316	Belongs to the HesB IscA family
HB763_RS07775	COG0633	Ferredoxin
HB763_RS07780	COG2975	iron-sulfur cluster assembly
HB763_RS07815	COG2976	Protein conserved in bacteria
HB763_RS07820	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB763_RS07835	COG2203	Gaf domain
HB763_RS07835	COG2199	diguanylate cyclase activity
HB763_RS07850	COG0516	GMP reductase activity
HB763_RS07850	COG0517	IMP dehydrogenase activity
HB763_RS07860	COG1757	Na H antiporter
HB763_RS07870	COG1584	GPR1 FUN34 yaaH family protein
HB763_RS07875	COG1115	amino acid carrier protein
HB763_RS07885	COG0583	DNA-binding transcription factor activity
HB763_RS07890	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HB763_RS07895	COG0668	transmembrane transport
HB763_RS07905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HB763_RS07925	COG1289	transmembrane transporter activity
HB763_RS07930	COG0583	DNA-binding transcription factor activity
HB763_RS07945	COG2867	negative regulation of translational initiation
HB763_RS07950	COG2914	Belongs to the UPF0125 (RnfH) family
HB763_RS07955	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HB763_RS07960	COG0456	acetyltransferase
HB763_RS07965	COG0497	DNA recombination
HB763_RS07980	COG1301	dicarboxylic acid transport
HB763_RS07985	COG0443	Heat shock 70 kDa protein
HB763_RS08000	COG4969	Belongs to the N-Me-Phe pilin family
HB763_RS08020	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HB763_RS08025	COG0590	tRNA wobble adenosine to inosine editing
HB763_RS08035	COG0047	phosphoribosylformylglycinamidine synthase activity
HB763_RS08035	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HB763_RS08120	COG2195	Cleaves the N-terminal amino acid of tripeptides
HB763_RS08125	COG2252	PERMEase
HB763_RS08135	COG1073	alpha beta
HB763_RS08150	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HB763_RS08155	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HB763_RS08160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HB763_RS08160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HB763_RS08185	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HB763_RS08190	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HB763_RS08200	COG0142	geranyltranstransferase activity
HB763_RS08210	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HB763_RS08225	COG0583	DNA-binding transcription factor activity
HB763_RS08235	COG2363	Small membrane protein
HB763_RS08255	COG1611	Belongs to the LOG family
HB763_RS08280	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
HB763_RS08295	COG1464	Belongs to the NlpA lipoprotein family
HB763_RS08300	COG2011	ABC-type metal ion transport system permease component
HB763_RS08305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HB763_RS08310	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HB763_RS08320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB763_RS08320	COG1263	PTS System
HB763_RS08325	COG0366	Alpha amylase catalytic
HB763_RS08340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HB763_RS08345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HB763_RS08365	COG1686	Belongs to the peptidase S11 family
HB763_RS08370	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HB763_RS08375	COG0772	Belongs to the SEDS family
HB763_RS08380	COG0768	penicillin binding
HB763_RS08390	COG0799	negative regulation of ribosome biogenesis
HB763_RS08395	COG1466	dna polymerase III delta subunit
HB763_RS08400	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
HB763_RS08410	COG2888	peptidyl-tyrosine sulfation
HB763_RS08415	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HB763_RS08420	COG4535	Mg2 and Co2 transporter CorC
HB763_RS08430	COG1702	phosphate starvation-inducible protein PhoH
HB763_RS08440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB763_RS08560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HB763_RS08585	COG2890	protein-(glutamine-N5) methyltransferase activity
HB763_RS08590	COG3094	Invasion gene expression up-regulator, SirB
HB763_RS08595	COG2912	Transglutaminase-like superfamily
HB763_RS08605	COG0737	Belongs to the 5'-nucleotidase family
HB763_RS08610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HB763_RS08615	COG1187	pseudouridine synthase activity
HB763_RS08620	COG2840	Smr protein MutS2
HB763_RS08660	COG2608	mercury ion transmembrane transporter activity
HB763_RS08660	COG2217	Heavy metal translocating P-type atpase
HB763_RS08670	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HB763_RS08725	COG0835	chemotaxis
HB763_RS08725	COG0784	Response regulator, receiver
HB763_RS08730	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HB763_RS08735	COG1815	bacterial-type flagellum-dependent cell motility
HB763_RS08740	COG1558	bacterial-type flagellum-dependent cell motility
HB763_RS08750	COG1749	Flagellar hook protein flgE
HB763_RS08755	COG4787	bacterial-type flagellum-dependent cell motility
HB763_RS08765	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HB763_RS08770	COG1706	bacterial-type flagellum-dependent cell motility
HB763_RS08775	COG1705	Flagellar rod assembly protein muramidase FlgJ
HB763_RS08775	COG3951	Flagellar rod assembly protein muramidase FlgJ
HB763_RS08790	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_RS08795	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_RS08800	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_RS08805	COG2190	(PTS) system
HB763_RS08810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HB763_RS08815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB763_RS08820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HB763_RS08825	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
HB763_RS08850	COG3385	transposase activity
HB763_RS08865	COG0330	HflC and HflK could
HB763_RS08870	COG3118	belongs to the thioredoxin family
HB763_RS08880	COG0300	oxidoreductase activity
HB763_RS08885	COG1090	epimerase
HB763_RS08895	COG0622	Phosphoesterase
HB763_RS08915	COG3710	Transcriptional regulator
HB763_RS08930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HB763_RS08935	COG3104	oligopeptide transport
HB763_RS08940	COG0250	Participates in transcription elongation, termination and antitermination
HB763_RS08945	COG0367	asparagine synthase
HB763_RS08950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HB763_RS08950	COG4651	solute:proton antiporter activity
HB763_RS08955	COG1940	carbohydrate kinase activity
HB763_RS08955	COG1846	Transcriptional regulator
HB763_RS08960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HB763_RS08965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB763_RS08965	COG2190	(PTS) system
HB763_RS08965	COG1263	PTS System
HB763_RS08975	COG2165	general secretion pathway protein
HB763_RS08980	COG0735	belongs to the Fur family
HB763_RS09000	COG0596	Alpha beta hydrolase
HB763_RS09005	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HB763_RS09010	COG0033	Phosphoglucomutase
HB763_RS09020	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HB763_RS09035	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HB763_RS09040	COG1053	succinate dehydrogenase
HB763_RS09050	COG0567	Dehydrogenase, E1 component
HB763_RS09055	COG0508	dehydrogenase complex catalyzes the overall conversion of
HB763_RS09070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB763_RS09075	COG1121	(ABC) transporter
HB763_RS09080	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HB763_RS09085	COG4977	sequence-specific DNA binding
HB763_RS09090	COG1918	ferrous iron import across plasma membrane
HB763_RS09120	COG3102	Protein conserved in bacteria
HB763_RS09135	COG0788	formyltetrahydrofolate deformylase activity
HB763_RS09140	COG1199	ATP-dependent helicase activity
HB763_RS09145	COG1214	PFAM Peptidase M22, glycoprotease
HB763_RS09155	COG3065	identical protein binding
HB763_RS09160	COG2267	carboxylic ester hydrolase activity
HB763_RS09165	COG0318	PFAM AMP-dependent synthetase and ligase
HB763_RS09170	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HB763_RS09175	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HB763_RS09180	COG2894	cell division
HB763_RS09195	COG2951	lytic endotransglycosylase activity
HB763_RS09205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB763_RS09220	COG2226	methyltransferase
HB763_RS09235	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_RS09245	COG1169	isochorismate synthase
HB763_RS09250	COG1021	2,3-dihydroxybenzoate-AMP ligase
HB763_RS09255	COG1535	isochorismatase
HB763_RS09255	COG3433	isochorismatase activity
HB763_RS09260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB763_RS09260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB763_RS09270	COG2977	Belongs to the P-Pant transferase superfamily
HB763_RS09275	COG4771	TonB-dependent receptor
HB763_RS09285	COG0513	Belongs to the DEAD box helicase family
HB763_RS09290	COG0569	domain protein
HB763_RS09295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB763_RS09315	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HB763_RS09320	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HB763_RS09325	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HB763_RS09360	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HB763_RS09365	COG0776	regulation of translation
HB763_RS09370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB763_RS09375	COG1555	photosystem II stabilization
HB763_RS09395	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HB763_RS09400	COG0436	Aminotransferase
HB763_RS09405	COG1169	isochorismate synthase
HB763_RS09415	COG0596	Alpha beta hydrolase
HB763_RS09420	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HB763_RS09435	COG2190	(PTS) system
HB763_RS09435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB763_RS09435	COG1263	PTS System
HB763_RS09440	COG0583	DNA-binding transcription factor activity
HB763_RS09450	COG2855	membrane
HB763_RS09505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB763_RS09525	COG1522	sequence-specific DNA binding
HB763_RS09530	COG1946	Acyl-CoA thioesterase
HB763_RS09535	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HB763_RS09550	COG3706	GGDEF domain
HB763_RS09585	COG1061	Type III restriction enzyme res subunit
HB763_RS09600	COG0732	type I restriction modification DNA specificity domain
HB763_RS09650	COG3344	reverse transcriptase
HB763_RS09695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HB763_RS09700	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HB763_RS09705	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
HB763_RS09710	COG0517	IMP dehydrogenase activity
HB763_RS09710	COG0516	GMP reductase activity
HB763_RS09720	COG2217	Heavy metal translocating P-type atpase
HB763_RS09740	COG0537	adenosine 5'-monophosphoramidase activity
HB763_RS09770	COG1252	NADH dehydrogenase
HB763_RS09785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HB763_RS09795	COG4591	ABC-type transport system involved in lipoprotein release permease component
HB763_RS09800	COG1136	(ABC) transporter
HB763_RS09805	COG4591	ABC-type transport system involved in lipoprotein release permease component
HB763_RS09815	COG0658	competence protein
HB763_RS09815	COG2333	competence protein COMEC
HB763_RS09820	COG1132	(ABC) transporter
HB763_RS09840	COG2719	SpoVR family
HB763_RS09845	COG2718	Belongs to the UPF0229 family
HB763_RS09850	COG2766	serine protein kinase
HB763_RS09865	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HB763_RS09875	COG1882	Formate acetyltransferase
HB763_RS09910	COG0708	Exodeoxyribonuclease III
HB763_RS09920	COG3923	Primosomal replication protein n
HB763_RS09925	COG0730	response to heat
HB763_RS09930	COG1199	ATP-dependent helicase activity
HB763_RS09940	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HB763_RS09945	COG1187	pseudouridine synthase activity
HB763_RS09955	COG1278	Cold shock
HB763_RS09965	COG0542	response to heat
HB763_RS09970	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HB763_RS10000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HB763_RS10005	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB763_RS10010	COG0297	glycogen (starch) synthase activity
HB763_RS10030	COG3070	regulator of competence-specific genes
HB763_RS10045	COG0745	RESPONSE REGULATOR receiver
HB763_RS10050	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HB763_RS10055	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB763_RS10065	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HB763_RS10070	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HB763_RS10090	COG4067	protein conserved in archaea
HB763_RS10090	COG0189	ligase activity
HB763_RS10105	COG1801	Protein of unknown function DUF72
HB763_RS10120	COG0840	transmembrane signaling receptor activity
HB763_RS10125	COG0632	four-way junction helicase activity
HB763_RS10135	COG1271	oxidase subunit
HB763_RS10140	COG1294	oxidase, subunit
HB763_RS10145	COG4890	Cyd operon protein YbgT
HB763_RS10155	COG0824	Thioesterase
HB763_RS10160	COG0811	peptide transport
HB763_RS10175	COG0823	Involved in the tonB-independent uptake of proteins
HB763_RS10180	COG2885	chlorophyll binding
HB763_RS10185	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HB763_RS10200	COG3766	membrane
HB763_RS10210	COG0754	glutathionylspermidine amidase activity
HB763_RS10220	COG0784	Response regulator, receiver
HB763_RS10220	COG2205	protein histidine kinase activity
HB763_RS10235	COG0514	ATP-dependent DNA helicase (RecQ)
HB763_RS10330	COG4669	(LipO)protein
HB763_RS10360	COG3177	Filamentation induced by cAMP protein fic
HB763_RS10370	COG0583	DNA-binding transcription factor activity
HB763_RS10375	COG4792	protein secretion
HB763_RS10380	COG4791	protein targeting
HB763_RS10385	COG4794	Type iii secretion
HB763_RS10390	COG4790	Type iii secretion
HB763_RS10460	COG0457	Tetratricopeptide repeat
HB763_RS10505	COG2824	Alkylphosphonate utilization operon protein PhnA
HB763_RS10515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB763_RS10520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB763_RS10535	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HB763_RS10555	COG3568	Endonuclease Exonuclease Phosphatase
HB763_RS10570	COG4934	collagen metabolic process
HB763_RS10575	COG0402	S-adenosylhomocysteine deaminase activity
HB763_RS10600	COG0583	DNA-binding transcription factor activity
HB763_RS10610	COG0686	Belongs to the AlaDH PNT family
HB763_RS10620	COG1674	ftsk spoiiie
HB763_RS10630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HB763_RS10640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HB763_RS10660	COG2226	methyltransferase
HB763_RS10685	COG0300	oxidoreductase activity
HB763_RS10700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HB763_RS10720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HB763_RS10740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB763_RS10750	COG1757	Na H antiporter
HB763_RS10760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HB763_RS10770	COG0131	Imidazoleglycerol-phosphate dehydratase
HB763_RS10770	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HB763_RS10775	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HB763_RS10780	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HB763_RS10790	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HB763_RS10790	COG0140	phosphoribosyl-ATP diphosphatase activity
HB763_RS10795	COG3012	SEC-C Motif Domain Protein
HB763_RS10800	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HB763_RS10805	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HB763_RS10810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HB763_RS10815	COG0215	cysteine-tRNA ligase activity
HB763_RS10820	COG1435	thymidine kinase activity
HB763_RS10825	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HB763_RS10845	COG2116	formate transmembrane transporter activity
HB763_RS10855	COG0390	transport system, permease component
HB763_RS10860	COG4459	periplasmic nitrate reductase
HB763_RS10865	COG3005	denitrification pathway
HB763_RS10870	COG0243	molybdopterin cofactor binding
HB763_RS10885	COG1121	(ABC) transporter
HB763_RS10890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB763_RS10895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB763_RS10900	COG1227	inorganic diphosphatase activity
HB763_RS10910	COG4172	Belongs to the ABC transporter superfamily
HB763_RS10920	COG4171	peptide transport system, permease
HB763_RS10925	COG4168	peptide transport system, permease
HB763_RS10935	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HB763_RS10940	COG1842	Phage shock protein A
HB763_RS10950	COG1983	PspC domain protein
HB763_RS10960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB763_RS10970	COG2818	Glycosylase
HB763_RS10990	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HB763_RS10995	COG0626	cystathionine gamma-synthase activity
HB763_RS11005	COG0733	neurotransmitter:sodium symporter activity
HB763_RS11010	COG0564	pseudouridine synthase activity
HB763_RS11025	COG2814	Major facilitator Superfamily
HB763_RS11035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HB763_RS11040	COG4136	ATPase activity
HB763_RS11045	COG4135	transport system, permease component
HB763_RS11050	COG4134	Bacterial extracellular solute-binding protein
HB763_RS11065	COG0659	secondary active sulfate transmembrane transporter activity
HB763_RS11075	COG3313	Fe-S protein
HB763_RS11130	COG1061	Type III restriction enzyme res subunit
HB763_RS11135	COG1187	pseudouridine synthase activity
HB763_RS11140	COG2814	Major facilitator Superfamily
HB763_RS11150	COG0702	epimerase
HB763_RS11155	COG0534	Mate efflux family protein
HB763_RS11160	COG4181	ATPase activity
HB763_RS11180	COG3335	DDE superfamily endonuclease
HB763_RS11195	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HB763_RS11205	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HB763_RS11215	COG1737	Transcriptional regulator
HB763_RS11220	COG0076	glutamate decarboxylase activity
HB763_RS11230	COG2431	L-lysine efflux transmembrane transporter activity
HB763_RS11240	COG3070	regulator of competence-specific genes
HB763_RS11255	COG4191	Histidine kinase
HB763_RS11255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB763_RS11265	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HB763_RS11295	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HB763_RS11300	COG4988	ABC transporter
HB763_RS11305	COG0492	ferredoxin-NADP+ reductase activity
HB763_RS11310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HB763_RS11330	COG0471	metal ion transport
HB763_RS11335	COG2949	membrane
HB763_RS11345	COG1643	Atp-dependent helicase
HB763_RS11450	COG0247	lactate metabolic process
HB763_RS11450	COG0277	FAD linked oxidase domain protein
HB763_RS11495	COG2986	histidine ammonia-lyase
HB763_RS11505	COG0010	Belongs to the arginase family
HB763_RS11515	COG2188	Transcriptional regulator
HB763_RS11550	COG0641	radical SAM
HB763_RS11555	COG3119	arylsulfatase activity
HB763_RS11570	COG0251	oxidation-reduction process
HB763_RS11620	COG0072	phenylalanine-tRNA ligase activity
HB763_RS11620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HB763_RS11625	COG1535	isochorismatase
HB763_RS11625	COG3433	isochorismatase activity
HB763_RS11630	COG1132	(ABC) transporter
HB763_RS11635	COG1132	(ABC) transporter
HB763_RS11635	COG2375	cellular response to nickel ion
HB763_RS11645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB763_RS11665	COG4774	siderophore transport
HB763_RS11670	COG4607	ABC-type enterochelin transport system periplasmic component
HB763_RS11675	COG4605	iron ion homeostasis
HB763_RS11680	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB763_RS11730	COG1346	cytolysis
HB763_RS11740	COG2925	Exonuclease
HB763_RS11750	COG1823	symporter activity
HB763_RS11755	COG0702	epimerase
HB763_RS11760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HB763_RS11770	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HB763_RS11780	COG2062	phosphohistidine phosphatase, SixA
HB763_RS11795	COG4139	cobalamin transport
HB763_RS11825	COG0583	DNA-binding transcription factor activity
HB763_RS11835	COG1451	nucleotide metabolic process
HB763_RS11915	COG2195	Cleaves the N-terminal amino acid of tripeptides
HB763_RS11930	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HB763_RS11940	COG0625	glutathione transferase activity
HB763_RS11985	COG0318	PFAM AMP-dependent synthetase and ligase
HB763_RS12000	COG0668	transmembrane transport
HB763_RS12005	COG3247	response to pH
HB763_RS12020	COG1846	Transcriptional regulator
HB763_RS12055	COG0784	Response regulator, receiver
HB763_RS12055	COG2205	protein histidine kinase activity
HB763_RS12080	COG3850	Histidine kinase
HB763_RS12080	COG4999	Histidine kinase
HB763_RS12080	COG3437	response regulator, receiver
HB763_RS12080	COG2205	protein histidine kinase activity
HB763_RS12085	COG3300	MHYT domain
HB763_RS12085	COG5001	Diguanylate cyclase
HB763_RS12100	COG0116	Belongs to the methyltransferase superfamily
HB763_RS12100	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HB763_RS12110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HB763_RS12115	COG1215	transferase activity, transferring glycosyl groups
HB763_RS12120	COG0438	transferase activity, transferring glycosyl groups
HB763_RS12150	COG0438	transferase activity, transferring glycosyl groups
HB763_RS12155	COG0438	transferase activity, transferring glycosyl groups
HB763_RS12160	COG2204	response regulator
HB763_RS12180	COG2885	chlorophyll binding
HB763_RS12190	COG1793	dna ligase
HB763_RS12200	COG0534	Mate efflux family protein
HB763_RS12205	COG0307	riboflavin synthase, alpha
HB763_RS12215	COG3001	Fructosamine kinase
HB763_RS12220	COG2201	protein-glutamate methylesterase activity
HB763_RS12225	COG3706	GGDEF domain
HB763_RS12235	COG0791	NLP P60 protein
HB763_RS12240	COG0840	transmembrane signaling receptor activity
HB763_RS12285	COG3148	PFAM DTW domain containing protein
HB763_RS12290	COG1940	carbohydrate kinase activity
HB763_RS12300	COG0303	'Molybdopterin
HB763_RS12310	COG3842	ATPase activity
HB763_RS12315	COG4662	Binding-protein-dependent transport system inner membrane component
HB763_RS12325	COG2204	response regulator
HB763_RS12330	COG4191	Histidine kinase
HB763_RS12345	COG0488	(ABC) transporter
HB763_RS12350	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HB763_RS12370	COG3381	protein complex oligomerization
HB763_RS12380	COG0243	molybdopterin cofactor binding
HB763_RS12380	COG3383	formate dehydrogenase (NAD+) activity
HB763_RS12385	COG0437	4 iron, 4 sulfur cluster binding
HB763_RS12400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HB763_RS12405	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HB763_RS12415	COG1177	transmembrane transport
HB763_RS12425	COG3842	ATPase activity
HB763_RS12450	COG0589	response to stress
HB763_RS12455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB763_RS12470	COG2217	Heavy metal translocating P-type atpase
HB763_RS12480	COG2010	Cytochrome c
HB763_RS12495	COG3278	Belongs to the heme-copper respiratory oxidase family
HB763_RS12510	COG2205	protein histidine kinase activity
HB763_RS12510	COG0784	Response regulator, receiver
HB763_RS12540	COG1067	ATP-dependent peptidase activity
HB763_RS12560	COG0488	(ABC) transporter
HB763_RS12585	COG2902	Dehydrogenase
HB763_RS12595	COG0308	aminopeptidase N
HB763_RS12610	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HB763_RS12615	COG1956	GAF domain-containing protein
HB763_RS12620	COG1132	(ABC) transporter
HB763_RS12625	COG2995	paraquat-inducible protein a
HB763_RS12630	COG3008	intermembrane lipid transfer
HB763_RS12655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB763_RS12670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB763_RS12675	COG4597	amino acid ABC transporter
HB763_RS12680	COG0765	amino acid transport
HB763_RS12685	COG1126	abc transporter atp-binding protein
HB763_RS12690	COG0670	Belongs to the BI1 family
HB763_RS12695	COG2920	part of a sulfur-relay system
HB763_RS12700	COG1254	Belongs to the acylphosphatase family
HB763_RS12755	COG3706	GGDEF domain
HB763_RS12765	COG0602	queuosine metabolic process
HB763_RS12770	COG0561	phosphatase activity
HB763_RS12805	COG2828	Protein conserved in bacteria
HB763_RS12815	COG0372	Belongs to the citrate synthase family
HB763_RS12820	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HB763_RS12830	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HB763_RS12865	COG0730	response to heat
HB763_RS12875	COG2358	TRAP transporter, solute receptor (TAXI family
HB763_RS12880	COG1012	belongs to the aldehyde dehydrogenase family
HB763_RS12885	COG3284	Transcriptional regulator
HB763_RS12895	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HB763_RS12900	COG0363	glucosamine-6-phosphate deaminase activity
HB763_RS12905	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HB763_RS12910	COG4565	transcriptional regulatory protein
HB763_RS12915	COG3290	protein histidine kinase activity
HB763_RS12935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB763_RS12985	COG0517	IMP dehydrogenase activity
HB763_RS12985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HB763_RS12990	COG2801	Transposase and inactivated derivatives
HB763_RS13025	COG3335	DDE superfamily endonuclease
HB763_RS13120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HB763_RS13130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HB763_RS13140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HB763_RS13165	COG0583	DNA-binding transcription factor activity
HB763_RS13195	COG0534	Mate efflux family protein
HB763_RS13400	COG1280	lysine exporter protein (LysE YggA)
HB763_RS13410	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HB763_RS13415	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HB763_RS13465	COG1404	Belongs to the peptidase S8 family
HB763_RS13480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB763_RS13490	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HB763_RS13500	COG0215	cysteine-tRNA ligase activity
HB763_RS13515	COG1368	sulfuric ester hydrolase activity
HB763_RS13540	COG1115	amino acid carrier protein
HB763_RS13570	COG1280	lysine exporter protein (LysE YggA)
HB763_RS13575	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HB763_RS13600	COG1280	lysine exporter protein (LysE YggA)
HB763_RS13610	COG0531	amino acid
HB763_RS13640	COG3063	Type IV pilus biogenesis stability protein PilW
HB763_RS13665	COG1643	Atp-dependent helicase
HB763_RS13700	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HB763_RS13705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB763_RS13740	COG3227	Zinc metalloprotease (Elastase)
HB763_RS13770	COG3706	GGDEF domain
HB763_RS13780	COG0443	Heat shock 70 kDa protein
HB763_RS13785	COG0443	Heat shock 70 kDa protein
HB763_RS13810	COG0583	DNA-binding transcription factor activity
HB763_RS13815	COG2165	general secretion pathway protein
HB763_RS13820	COG1132	(ABC) transporter
HB763_RS13825	COG1132	(ABC) transporter
HB763_RS13845	COG0814	amino acid
HB763_RS13850	COG1454	alcohol dehydrogenase
HB763_RS13855	COG4221	oxidoreductase activity
HB763_RS13860	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HB763_RS13870	COG0861	Integral membrane protein TerC family
HB763_RS13880	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HB763_RS13885	COG1328	CTP reductase activity
HB763_RS13890	COG1280	lysine exporter protein (LysE YggA)
HB763_RS13935	COG3340	Belongs to the peptidase S51 family
HB763_RS13950	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_RS13965	COG2977	Belongs to the P-Pant transferase superfamily
HB763_RS13975	COG3321	synthase
HB763_RS13975	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_RS13975	COG0300	oxidoreductase activity
HB763_RS13975	COG0318	PFAM AMP-dependent synthetase and ligase
HB763_RS13975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB763_RS13990	COG1216	Glycosyl transferase, family 2
HB763_RS14005	COG0284	orotidine-5'-phosphate decarboxylase activity
HB763_RS14010	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HB763_RS14020	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HB763_RS14025	COG0284	orotidine-5'-phosphate decarboxylase activity
HB763_RS14080	COG1683	Conserved Protein
HB763_RS14115	COG1192	Involved in chromosome partitioning
HB763_RS14130	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HB763_RS14140	COG3335	DDE superfamily endonuclease
HB763_RS14225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB763_RS14240	COG3106	COG3106 Predicted ATPase
HB763_RS14255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HB763_RS14260	COG0784	Response regulator, receiver
HB763_RS14260	COG2205	protein histidine kinase activity
HB763_RS14275	COG0814	amino acid
HB763_RS14280	COG1760	l-serine dehydratase
HB763_RS14285	COG5001	Diguanylate cyclase
HB763_RS14285	COG3300	MHYT domain
HB763_RS14300	COG2197	response regulator
HB763_RS14305	COG0720	synthase
HB763_RS14315	COG0017	Asparaginyl-tRNA synthetase
HB763_RS14330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB763_RS14350	COG1448	Aminotransferase
HB763_RS14370	COG0840	transmembrane signaling receptor activity
HB763_RS14375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB763_RS14380	COG1846	Transcriptional regulator
HB763_RS14405	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HB763_RS14420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HB763_RS14425	COG3108	Peptidase M15
HB763_RS14430	COG2989	Protein conserved in bacteria
HB763_RS14495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB763_RS14500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB763_RS14510	COG1058	Belongs to the CinA family
HB763_RS14510	COG1546	Belongs to the CinA family
HB763_RS14525	COG0019	diaminopimelate decarboxylase activity
HB763_RS14565	COG0322	excinuclease ABC activity
HB763_RS14570	COG2197	response regulator
HB763_RS14575	COG0417	DNA replication proofreading
HB763_RS14595	COG1187	pseudouridine synthase activity
HB763_RS14605	COG0009	L-threonylcarbamoyladenylate synthase
HB763_RS14610	COG0613	PHP domain protein
HB763_RS14620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HB763_RS14625	COG0512	Glutamine amidotransferase of anthranilate synthase
HB763_RS14635	COG0135	phosphoribosylanthranilate isomerase activity
HB763_RS14635	COG0134	indole-3-glycerol-phosphate synthase activity
HB763_RS14645	COG0159	tryptophan synthase activity
HB763_RS14650	COG1301	dicarboxylic acid transport
HB763_RS14680	COG2350	Protein conserved in bacteria
HB763_RS14710	COG1716	ATPase activity
HB763_RS14710	COG5001	Diguanylate cyclase
HB763_RS14715	COG1032	radical SAM domain protein
HB763_RS14745	COG2175	clavaminate synthase activity
HB763_RS14760	COG0840	transmembrane signaling receptor activity
HB763_RS14770	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HB763_RS14775	COG0463	Glycosyl transferase, family 2
HB763_RS14780	COG0745	RESPONSE REGULATOR receiver
HB763_RS14785	COG3850	Histidine kinase
HB763_RS14785	COG5002	protein histidine kinase activity
HB763_RS14830	COG3615	Tellurite resistance protein tehB
HB763_RS14840	COG2207	Transcriptional regulator
HB763_RS14840	COG3708	Transcriptional regulator
HB763_RS14850	COG1217	gtp-binding protein TYPA
HB763_RS14860	COG2176	DNA-directed DNA polymerase activity
HB763_RS14875	COG0577	efflux transmembrane transporter activity
HB763_RS14875	COG1136	(ABC) transporter
HB763_RS14880	COG0577	efflux transmembrane transporter activity
HB763_RS14880	COG1136	(ABC) transporter
HB763_RS14885	COG0577	efflux transmembrane transporter activity
HB763_RS14895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB763_RS14905	COG3064	Membrane
HB763_RS14905	COG1073	alpha beta
HB763_RS14905	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
HB763_RS14920	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HB763_RS14930	COG3118	belongs to the thioredoxin family
HB763_RS14935	COG4232	protein-disulfide reductase activity
HB763_RS14950	COG2995	paraquat-inducible protein a
HB763_RS14955	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HB763_RS14955	COG3008	intermembrane lipid transfer
HB763_RS14960	COG3009	Protein conserved in bacteria
HB763_RS14975	COG4166	transmembrane transport
HB763_RS14985	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HB763_RS14990	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HB763_RS15000	COG0539	negative regulation of cytoplasmic translation
HB763_RS15010	COG0616	signal peptide processing
HB763_RS15015	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_RS15035	COG0784	Response regulator, receiver
HB763_RS15035	COG0835	chemotaxis
HB763_RS15040	COG1940	carbohydrate kinase activity
HB763_RS15065	COG4667	esterase of the alpha-beta hydrolase superfamily
HB763_RS15080	COG0733	neurotransmitter:sodium symporter activity
HB763_RS15100	COG1263	PTS System
HB763_RS15100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB763_RS15105	COG0084	hydrolase, TatD family'
HB763_RS15120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HB763_RS15150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HB763_RS15165	COG1399	metal-binding, possibly nucleic acid-binding protein
HB763_RS15170	COG0424	maF-like protein
HB763_RS15175	COG0564	pseudouridine synthase activity
HB763_RS15180	COG1530	ribonuclease E activity
HB763_RS15185	COG0659	secondary active sulfate transmembrane transporter activity
HB763_RS15190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HB763_RS15195	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HB763_RS15225	COG2186	Transcriptional regulator
HB763_RS15235	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HB763_RS15240	COG0653	protein targeting
HB763_RS15245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HB763_RS15260	COG1122	ATPase activity
HB763_RS15265	COG4120	Belongs to the binding-protein-dependent transport system permease family
HB763_RS15285	COG0280	phosphate acetyltransferase
HB763_RS15285	COG0857	belongs to the CobB CobQ family
HB763_RS15290	COG0435	Glutathione S-transferase
HB763_RS15300	COG0444	Belongs to the ABC transporter superfamily
HB763_RS15305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB763_RS15310	COG0601	transmembrane transport
HB763_RS15320	COG0314	molybdopterin synthase activity
HB763_RS15325	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HB763_RS15335	COG0521	Mo-molybdopterin cofactor biosynthetic process
HB763_RS15340	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HB763_RS15345	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HB763_RS15360	COG0556	nucleotide-excision repair
HB763_RS15420	COG4657	Part of a membrane complex involved in electron transport
HB763_RS15430	COG4656	Part of a membrane complex involved in electron transport
HB763_RS15435	COG4658	electron transport chain
HB763_RS15440	COG4659	FMN binding
HB763_RS15445	COG4660	Part of a membrane complex involved in electron transport
HB763_RS15450	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HB763_RS15485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HB763_RS15490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HB763_RS15570	COG2261	transglycosylase associated protein
HB763_RS15670	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HB763_RS15745	COG0346	lactoylglutathione lyase activity
HB763_RS15755	COG2885	chlorophyll binding
HB763_RS15765	COG2056	Na+-H+ antiporter family
HB763_RS15780	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HB763_RS15795	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_RS15800	COG1454	alcohol dehydrogenase
HB763_RS15800	COG1012	belongs to the aldehyde dehydrogenase family
HB763_RS15805	COG2095	MarC family integral membrane protein
HB763_RS15810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB763_RS15815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HB763_RS15820	COG1757	Na H antiporter
HB763_RS15845	COG3083	sulfuric ester hydrolase activity
HB763_RS15860	COG4269	membrane
HB763_RS15870	COG0123	including yeast histone deacetylase and acetoin utilization protein
HB763_RS15885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HB763_RS15890	COG0778	Nitroreductase
HB763_RS15895	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB763_RS15895	COG1902	pentaerythritol trinitrate reductase activity
HB763_RS15900	COG0616	signal peptide processing
HB763_RS15905	COG0252	asparaginase activity
HB763_RS15910	COG3139	Protein of unknown function (DUF1315)
HB763_RS15920	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB763_RS15925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HB763_RS15950	COG0765	amino acid transport
HB763_RS15955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB763_RS15960	COG0765	amino acid transport
HB763_RS15965	COG1126	abc transporter atp-binding protein
HB763_RS15975	COG1979	alcohol dehydrogenase
HB763_RS15980	COG2207	Transcriptional regulator
HB763_RS15990	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB763_RS16000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB763_RS16020	COG0546	phosphoglycolate phosphatase activity
HB763_RS16035	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HB763_RS16040	COG0513	Belongs to the DEAD box helicase family
HB763_RS16050	COG3385	transposase activity
HB763_RS16065	COG3038	cytochrome b561
HB763_RS16075	COG2116	formate transmembrane transporter activity
HB763_RS16080	COG0583	DNA-binding transcription factor activity
HB763_RS16090	COG3593	DNA synthesis involved in DNA repair
HB763_RS16095	COG0737	Belongs to the 5'-nucleotidase family
HB763_RS16110	COG1410	methionine synthase
HB763_RS16110	COG0646	methionine synthase
HB763_RS16115	COG0076	glutamate decarboxylase activity
HB763_RS16120	COG0307	riboflavin synthase, alpha
HB763_RS16155	COG2267	carboxylic ester hydrolase activity
HB763_RS16160	COG2067	long-chain fatty acid transport protein
HB763_RS16170	COG0501	Belongs to the peptidase M48B family
HB763_RS16175	COG2050	protein possibly involved in aromatic compounds catabolism
HB763_RS16220	COG5001	Diguanylate cyclase
HB763_RS16220	COG3300	MHYT domain
HB763_RS16235	COG4181	ATPase activity
HB763_RS16240	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HB763_RS16250	COG1984	allophanate hydrolase subunit 2
HB763_RS16255	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HB763_RS16265	COG3447	MASE1 domain protein
HB763_RS16265	COG5001	Diguanylate cyclase
HB763_RS16265	COG5002	protein histidine kinase activity
HB763_RS16270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HB763_RS16280	COG0583	DNA-binding transcription factor activity
HB763_RS16285	COG0045	succinate-CoA ligase (ADP-forming) activity
HB763_RS16285	COG1042	CoA-binding domain protein
HB763_RS16285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB763_RS16305	COG0023	Translation Initiation Factor
HB763_RS16400	COG3140	Belongs to the UPF0181 family
HB763_RS16425	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HB763_RS16430	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HB763_RS16450	COG3706	GGDEF domain
HB763_RS16450	COG4251	negative regulation of phosphorylation
HB763_RS16450	COG2203	Gaf domain
HB763_RS16450	COG5001	Diguanylate cyclase
HB763_RS16460	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HB763_RS16465	COG4149	molybdate abc transporter
HB763_RS16470	COG0725	ABC transporter, periplasmic molybdate-binding protein
HB763_RS16480	COG3111	PFAM Bacterial OB fold (BOF) protein
HB763_RS16505	COG0534	Mate efflux family protein
HB763_RS16510	COG0602	queuosine metabolic process
HB763_RS16515	COG1328	CTP reductase activity
HB763_RS16570	COG2197	response regulator
HB763_RS16575	COG3851	Histidine kinase
HB763_RS16580	COG2271	Major facilitator Superfamily
HB763_RS16585	COG1482	cell wall glycoprotein biosynthetic process
HB763_RS16620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HB763_RS16625	COG3118	belongs to the thioredoxin family
HB763_RS16650	COG0840	transmembrane signaling receptor activity
HB763_RS16655	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HB763_RS16730	COG0277	FAD linked oxidase domain protein
HB763_RS16735	COG0583	DNA-binding transcription factor activity
HB763_RS16750	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HB763_RS16765	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HB763_RS16775	COG1288	antiporter activity
HB763_RS16785	COG3040	lipid binding
HB763_RS16815	COG3469	chitinase activity
HB763_RS16825	COG0419	ATPase involved in DNA repair
HB763_RS16830	COG0420	3'-5' exonuclease activity
HB763_RS16860	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HB763_RS16875	COG0840	transmembrane signaling receptor activity
HB763_RS16900	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HB763_RS16900	COG2755	lipolytic protein G-D-S-L family
HB763_RS16910	COG5642	Protein of unknown function (DUF2384)
HB763_RS16950	COG0671	phosphoesterase, PA-phosphatase related
HB763_RS16960	COG2962	Rard protein
HB763_RS16970	COG0835	chemotaxis
HB763_RS16970	COG0784	Response regulator, receiver
HB763_RS16975	COG0778	Nitroreductase
HB763_RS16995	COG3179	chitinase
HB763_RS17040	COG1522	sequence-specific DNA binding
HB763_RS17080	COG3335	DDE superfamily endonuclease
HB763_RS17110	COG3501	Rhs element vgr protein
HB763_RS17150	COG0739	heme binding
HB763_RS17165	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HB763_RS17195	COG3069	C4-dicarboxylate transmembrane transporter activity
HB763_RS17225	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HB763_RS17235	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HB763_RS17295	COG2205	protein histidine kinase activity
HB763_RS17295	COG2198	Histidine kinase
HB763_RS17295	COG0784	Response regulator, receiver
HB763_RS17300	COG1879	ABC-type sugar transport system periplasmic component
HB763_RS17310	COG0210	DNA helicase
HB763_RS17315	COG1289	transmembrane transporter activity
HB763_RS17340	COG0789	Transcriptional regulator
HB763_RS17345	COG4604	ABC transporter, ATP-binding protein
HB763_RS17350	COG4605	iron ion homeostasis
HB763_RS17355	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB763_RS17360	COG4607	ABC-type enterochelin transport system periplasmic component
HB763_RS17375	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HB763_RS17385	COG1609	Transcriptional regulator
HB763_RS17390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB763_RS17395	COG1879	ABC-type sugar transport system periplasmic component
HB763_RS17400	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB763_RS17405	COG1129	ABC transporter
HB763_RS17415	COG5001	Diguanylate cyclase
HB763_RS17420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HB763_RS17425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HB763_RS17520	COG0330	HflC and HflK could
HB763_RS17530	COG0517	IMP dehydrogenase activity
HB763_RS17530	COG4175	Glycine betaine
HB763_RS17535	COG4176	ABC-type proline glycine betaine transport system permease component
HB763_RS17570	COG2885	chlorophyll binding
HB763_RS17610	COG0455	bacterial-type flagellum organization
HB763_RS17620	COG4964	Belongs to the GSP D family
HB763_RS17640	COG0583	DNA-binding transcription factor activity
HB763_RS17690	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HB763_RS17690	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HB763_RS17705	COG4989	oxidoreductase activity
HB763_RS17735	COG0303	'Molybdopterin
HB763_RS17740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HB763_RS17775	COG2897	thiosulfate sulfurtransferase activity
HB763_RS17795	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HB763_RS17800	COG0840	transmembrane signaling receptor activity
HB763_RS17810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB763_RS17815	COG2885	chlorophyll binding
HB763_RS17825	COG1612	heme a metabolic process
HB763_RS17850	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HB763_RS17865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HB763_RS17875	COG1280	lysine exporter protein (LysE YggA)
HB763_RS17895	COG0179	Fumarylacetoacetate (FAA) hydrolase
HB763_RS17910	COG0697	spore germination
HB763_RS17930	COG2814	Major facilitator Superfamily
HB763_RS17935	COG0583	DNA-binding transcription factor activity
HB763_RS17965	COG1120	ATPase activity
HB763_RS17970	COG5001	Diguanylate cyclase
HB763_RS17975	COG0739	heme binding
HB763_RS17995	COG3314	Sporulation integral membrane protein YlbJ
HB763_RS18010	COG0814	amino acid
HB763_RS18045	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HB763_RS18050	COG1120	ATPase activity
HB763_RS18080	COG0798	PFAM Bile acid sodium symporter
HB763_RS18095	COG1881	PFAM PEBP family protein
HB763_RS18105	COG0251	oxidation-reduction process
HB763_RS18110	COG2706	6-phosphogluconolactonase activity
HB763_RS18120	COG0800	Aldolase
HB763_RS18125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB763_RS18130	COG4145	pantothenate transmembrane transporter activity
HB763_RS18140	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HB763_RS18160	COG1131	(ABC) transporter
HB763_RS18165	COG0842	Transport permease protein
HB763_RS18200	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB763_RS18210	COG1280	lysine exporter protein (LysE YggA)
HB763_RS18215	COG0583	DNA-binding transcription factor activity
HB763_RS18225	COG0494	nUDIX hydrolase
HB763_RS18240	COG1858	cytochrome C peroxidase
HB763_RS18260	COG3335	DDE superfamily endonuclease
HB763_RS18275	COG1505	serine-type exopeptidase activity
HB763_RS18280	COG0488	(ABC) transporter
HB763_RS18290	COG0589	response to stress
HB763_RS18300	COG0584	glycerophosphoryl diester phosphodiesterase
HB763_RS18310	COG1175	transmembrane transport
HB763_RS18315	COG0395	ABC-type sugar transport system, permease component
HB763_RS18320	COG3842	ATPase activity
HB763_RS18355	COG0523	cobalamin synthesis protein
HB763_RS18365	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HB763_RS18375	COG4667	esterase of the alpha-beta hydrolase superfamily
HB763_RS18380	COG1741	Belongs to the pirin family
HB763_RS18385	COG1278	Cold shock
HB763_RS18400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HB763_RS18410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB763_RS18420	COG1686	Belongs to the peptidase S11 family
HB763_RS18425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB763_RS18430	COG0625	glutathione transferase activity
HB763_RS18495	COG1764	response to oxidative stress
HB763_RS18500	COG2084	Dehydrogenase
HB763_RS18505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB763_RS18510	COG0823	Involved in the tonB-independent uptake of proteins
HB763_RS18530	COG0455	bacterial-type flagellum organization
HB763_RS18540	COG3385	transposase activity
HB763_RS18555	COG2801	Transposase and inactivated derivatives
HB763_RS18770	COG0588	phosphoglycerate mutase activity
HB763_RS18800	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HB763_RS18800	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HB763_RS18820	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_RS18845	COG3746	phosphate-selective porin O and P
HB763_RS18865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB763_RS18905	COG0513	Belongs to the DEAD box helicase family
HB763_RS18930	COG0583	DNA-binding transcription factor activity
HB763_RS18950	COG1902	pentaerythritol trinitrate reductase activity
HB763_RS18955	COG3853	Toxic anion resistance protein (TelA)
HB763_RS18965	COG2255	four-way junction helicase activity
HB763_RS18980	COG3122	Protein conserved in bacteria
HB763_RS18985	COG2321	neutral zinc metallopeptidase
HB763_RS18995	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HB763_RS19000	COG1215	transferase activity, transferring glycosyl groups
HB763_RS19010	COG0583	DNA-binding transcription factor activity
HB763_RS19015	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HB763_RS19025	COG2207	Transcriptional regulator
HB763_RS19030	COG2807	transmembrane transport
HB763_RS19040	COG0574	Belongs to the PEP-utilizing enzyme family
HB763_RS19040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HB763_RS19065	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HB763_RS19075	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HB763_RS19110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB763_RS19140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB763_RS19190	COG4948	Mandelate Racemase Muconate Lactonizing
HB763_RS19230	COG4176	ABC-type proline glycine betaine transport system permease component
HB763_RS19235	COG3448	diguanylate cyclase activity
HB763_RS19235	COG4175	Glycine betaine
HB763_RS19250	COG0583	DNA-binding transcription factor activity
HB763_RS19260	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HB763_RS19310	COG2433	Pfam Transposase IS66
HB763_RS19330	COG3385	transposase activity
HB763_RS19365	COG1349	DNA-binding transcription factor activity
HB763_RS19370	COG0346	lactoylglutathione lyase activity
HB763_RS19375	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB763_RS19375	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB763_RS19385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB763_RS19405	COG1280	lysine exporter protein (LysE YggA)
HB763_RS19410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HB763_RS19425	COG0488	(ABC) transporter
HB763_RS19430	COG0435	Glutathione S-transferase
HB763_RS19435	COG0431	NADPH-dependent FMN reductase
HB763_RS19440	COG0583	DNA-binding transcription factor activity
HB763_RS19445	COG4628	conserved protein (DUF2132)
HB763_RS19450	COG0488	(ABC) transporter
HB763_RS19465	COG0346	lactoylglutathione lyase activity
HB763_RS19470	COG0384	phenazine biosynthesis protein PhzF
HB763_RS19500	COG2205	protein histidine kinase activity
HB763_RS19505	COG0745	RESPONSE REGULATOR receiver
HB763_RS19515	COG0454	-acetyltransferase
HB763_RS19525	COG2814	Major facilitator Superfamily
HB763_RS19535	COG2988	succinylglutamate desuccinylase activity
HB763_RS19550	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HB763_RS19565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB763_RS19575	COG4628	conserved protein (DUF2132)
HB763_RS19580	COG0583	DNA-binding transcription factor activity
HB763_RS19590	COG1686	Belongs to the peptidase S11 family
HB763_RS19615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB763_RS19630	COG0415	Belongs to the DNA photolyase family
HB763_RS19635	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HB763_RS19645	COG4667	esterase of the alpha-beta hydrolase superfamily
HB763_RS19650	COG2095	MarC family integral membrane protein
HB763_RS19660	COG1596	polysaccharide export
HB763_RS19670	COG3206	protein involved in exopolysaccharide biosynthesis
HB763_RS19670	COG0489	protein tyrosine kinase activity
HB763_RS19705	COG1301	dicarboxylic acid transport
HB763_RS19710	COG3339	Conserved Protein
HB763_RS19725	COG2207	Transcriptional regulator
HB763_RS19740	COG0366	Alpha amylase catalytic
HB763_RS19745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HB763_RS19750	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HB763_RS19755	COG1640	4-alpha-glucanotransferase
HB763_RS19760	COG0058	SHG alpha-glucan phosphorylase activity
HB763_RS19780	COG1999	signal sequence binding
HB763_RS19790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB763_RS19790	COG1263	PTS System
HB763_RS19800	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HB763_RS19830	COG2356	endonuclease I
HB763_RS19890	COG0456	acetyltransferase
HB763_RS19890	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HB763_RS19955	COG3385	transposase activity
HB763_RS19970	COG4580	involved in the transport of maltose and maltodextrins
HB763_RS19990	COG2814	Major facilitator Superfamily
HB763_RS20000	COG0739	heme binding
HB763_RS20030	COG3121	Chaperone
HB763_RS20035	COG3188	usher protein
HB763_RS20055	COG3335	DDE superfamily endonuclease
HB763_RS20070	COG0612	Peptidase, M16
HB763_RS20075	COG0840	transmembrane signaling receptor activity
HB763_RS20095	COG1335	isochorismatase
HB763_RS20100	COG1136	(ABC) transporter
HB763_RS20105	COG0577	efflux transmembrane transporter activity
HB763_RS20155	COG1764	response to oxidative stress
HB763_RS20160	COG1846	Transcriptional regulator
HB763_RS20180	COG3634	alkyl hydroperoxide reductase activity
HB763_RS20190	COG2610	gluconate transmembrane transporter activity
HB763_RS20195	COG3622	Belongs to the hyi family
HB763_RS20200	COG0235	Class ii aldolase
HB763_RS20205	COG3395	kinase activity
HB763_RS20210	COG2084	Dehydrogenase
HB763_RS20215	COG1349	DNA-binding transcription factor activity
HB763_RS20240	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HB763_RS20250	COG1522	sequence-specific DNA binding
HB763_RS20255	COG0544	peptidyl-prolyl cis-trans isomerase activity
HB763_RS20270	COG2258	MOSC domain
HB763_RS20275	COG2153	protein acetylation
HB763_RS20285	COG3713	MltA-interacting MipA family protein
HB763_RS20290	COG0513	Belongs to the DEAD box helicase family
HB763_RS20295	COG0667	Aldo Keto reductase
HB763_RS20320	COG1132	(ABC) transporter
HB763_RS20475	COG4166	transmembrane transport
HB763_RS20490	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HB763_RS20495	COG1263	PTS System
HB763_RS20495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HB763_RS20500	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HB763_RS20525	COG1444	tRNA N-acetyltransferase activity
HB763_RS20550	COG4608	Belongs to the ABC transporter superfamily
HB763_RS20555	COG0444	Belongs to the ABC transporter superfamily
HB763_RS20565	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HB763_RS20565	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HB763_RS20590	COG0772	Belongs to the SEDS family
HB763_RS20605	COG1136	(ABC) transporter
HB763_RS20625	COG3275	phosphorelay sensor kinase activity
HB763_RS20630	COG3279	Response regulator of the LytR AlgR family
HB763_RS20640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HB763_RS20660	COG0786	glutamate:sodium symporter activity
HB763_RS20665	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_RS20730	COG2897	thiosulfate sulfurtransferase activity
HB763_RS20740	COG1131	(ABC) transporter
HB763_RS20745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB763_RS20750	COG0786	glutamate:sodium symporter activity
HB763_RS20780	COG0561	phosphatase activity
HB763_RS20785	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HB763_RS20790	COG3623	hexulose-6-phosphate isomerase
HB763_RS20825	COG2259	Doxx family
HB763_RS20840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HB763_RS20910	COG1609	Transcriptional regulator
HB763_RS20925	COG0395	ABC-type sugar transport system, permease component
HB763_RS20930	COG2723	6-phospho-beta-galactosidase activity
HB763_RS20935	COG3842	ATPase activity
HB763_RS20940	COG1609	Transcriptional regulator
HB763_RS20950	COG0564	pseudouridine synthase activity
HB763_RS20955	COG0561	phosphatase activity
HB763_RS20975	COG3152	Membrane
HB763_RS20995	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HB763_RS21010	COG0583	DNA-binding transcription factor activity
HB763_RS21060	COG2076	Multidrug Resistance protein
HB763_RS21070	COG1357	PFAM Pentapeptide repeats (8 copies)
HB763_RS21075	COG3047	cAMP biosynthetic process
HB763_RS21165	COG0668	transmembrane transport
HB763_RS21210	COG3835	regulator
HB763_RS21215	COG1929	Belongs to the glycerate kinase type-1 family
HB763_RS21220	COG0477	Major facilitator Superfamily
HB763_RS21240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB763_RS21245	COG0697	spore germination
HB763_RS21290	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_RS21305	COG0671	phosphoesterase, PA-phosphatase related
HB763_RS21320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HB763_RS21325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB763_RS21330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB763_RS21335	COG1116	anion transmembrane transporter activity
HB763_RS21340	COG0351	phosphomethylpyrimidine kinase
HB763_RS21345	COG0312	modulator of DNA gyrase
HB763_RS21350	COG0312	modulator of DNA gyrase
HB763_RS21410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB763_RS21420	COG0584	glycerophosphoryl diester phosphodiesterase
HB763_RS21425	COG0745	RESPONSE REGULATOR receiver
HB763_RS21430	COG2205	protein histidine kinase activity
HB763_RS21445	COG0811	peptide transport
HB763_RS21450	COG0811	peptide transport
HB763_RS21455	COG0848	biopolymer transport protein
HB763_RS21500	COG0803	Belongs to the bacterial solute-binding protein 9 family
HB763_RS21505	COG1121	(ABC) transporter
HB763_RS21510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB763_RS21525	COG1770	oligopeptidase
HB763_RS21530	COG2814	Major facilitator Superfamily
HB763_RS21535	COG0010	Belongs to the arginase family
HB763_RS21540	COG1166	arginine decarboxylase activity
HB763_RS21550	COG4067	protein conserved in archaea
HB763_RS21550	COG0189	ligase activity
HB763_RS21555	COG0189	ligase activity
HB763_RS21575	COG0583	DNA-binding transcription factor activity
HB763_RS21615	COG1114	Component of the transport system for branched-chain amino acids
HB763_RS21630	COG0579	oxidoreductase
HB763_RS21635	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HB763_RS21650	COG3033	Beta-eliminating lyase
HB763_RS21665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HB763_RS21670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB763_RS21705	COG3706	GGDEF domain
HB763_RS21710	COG0415	Belongs to the DNA photolyase family
HB763_RS21715	COG3046	protein related to deoxyribodipyrimidine photolyase
HB763_RS21730	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB763_RS21730	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HB763_RS21735	COG1765	OsmC-like protein
HB763_RS21770	COG1011	Hydrolase
HB763_RS21795	COG3240	lipase activity
HB763_RS21815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HB763_RS21825	COG1840	ABC-type Fe3 transport system, periplasmic component
HB763_RS21830	COG3842	ATPase activity
HB763_RS21855	COG2990	Protein conserved in bacteria
HB763_RS21865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB763_RS21870	COG2866	Carboxypeptidase
HB763_RS21880	COG0583	DNA-binding transcription factor activity
HB763_RS21905	COG3104	oligopeptide transport
HB763_RS21910	COG1760	l-serine dehydratase
HB763_RS21935	COG0741	lytic transglycosylase activity
HB763_RS21935	COG1388	LysM domain
HB763_RS21955	COG1815	bacterial-type flagellum-dependent cell motility
HB763_RS21960	COG1558	bacterial-type flagellum-dependent cell motility
HB763_RS21965	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HB763_RS21970	COG1749	Flagellar hook protein flgE
HB763_RS21975	COG4787	bacterial-type flagellum-dependent cell motility
HB763_RS21980	COG4786	Flagellar basal body rod
HB763_RS21985	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HB763_RS21990	COG1706	bacterial-type flagellum-dependent cell motility
HB763_RS22000	COG4786	Flagellar basal body rod
HB763_RS22000	COG1256	bacterial-type flagellum assembly
HB763_RS22005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_RS22070	COG0384	phenazine biosynthesis protein PhzF
HB763_RS22080	COG1360	Flagellar Motor Protein
HB763_RS22085	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HB763_RS22090	COG1191	sigma factor activity
HB763_RS22095	COG1580	Controls the rotational direction of flagella during chemotaxis
HB763_RS22110	COG1516	flagellar protein fliS
HB763_RS22115	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HB763_RS22125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB763_RS22150	COG1987	bacterial-type flagellum assembly
HB763_RS22255	COG0346	lactoylglutathione lyase activity
HB763_RS22280	COG0745	RESPONSE REGULATOR receiver
HB763_RS22305	COG0156	8-amino-7-oxononanoate synthase activity
HB763_RS22310	COG1063	alcohol dehydrogenase
HB763_RS22350	COG1063	alcohol dehydrogenase
HB763_RS22375	COG2199	diguanylate cyclase activity
HB763_RS22375	COG2203	Gaf domain
HB763_RS22380	COG2223	nitrite transmembrane transporter activity
HB763_RS22385	COG1063	alcohol dehydrogenase
HB763_RS22395	COG0668	transmembrane transport
HB763_RS22405	COG1304	FMN binding
HB763_RS22415	COG1620	l-lactate permease
HB763_RS22420	COG0583	DNA-binding transcription factor activity
HB763_RS22425	COG1505	serine-type exopeptidase activity
HB763_RS22430	COG4172	Belongs to the ABC transporter superfamily
HB763_RS22440	COG1067	ATP-dependent peptidase activity
HB763_RS22450	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HB763_RS22470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HB763_RS22490	COG1122	ATPase activity
HB763_RS22500	COG1566	PFAM secretion protein HlyD family protein
HB763_RS22515	COG3706	GGDEF domain
HB763_RS22530	COG0813	purine-nucleoside phosphorylase activity
HB763_RS22535	COG3272	Protein of unknown function (DUF1722)
HB763_RS22540	COG0789	Transcriptional regulator
HB763_RS22545	COG0415	Belongs to the DNA photolyase family
HB763_RS22550	COG1388	LysM domain
HB763_RS22550	COG1376	ErfK ybiS ycfS ynhG family protein
HB763_RS22560	COG0513	Belongs to the DEAD box helicase family
HB763_RS22570	COG1770	oligopeptidase
HB763_RS22575	COG4771	TonB-dependent receptor
HB763_RS22595	COG0840	transmembrane signaling receptor activity
HB763_RS22605	COG0573	inorganic phosphate transmembrane transporter activity
HB763_RS22610	COG0581	inorganic phosphate transmembrane transporter activity
HB763_RS22615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HB763_RS22630	COG2304	oxidoreductase activity
HB763_RS22650	COG0714	Associated with various cellular activities
HB763_RS22655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB763_RS22670	COG2197	response regulator
HB763_RS22700	COG3852	Histidine kinase
HB763_RS22705	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_RS22735	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
HB763_RS22755	COG1252	NADH dehydrogenase
HB763_RS22760	COG1301	dicarboxylic acid transport
HB763_RS22765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB763_RS22790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB763_RS22790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB763_RS22790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB763_RS22795	COG2207	Transcriptional regulator
HB763_RS22805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB763_RS22810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB763_RS22820	COG2084	Dehydrogenase
HB763_RS22825	COG0753	catalase activity
HB763_RS22835	COG2130	NADP-dependent
HB763_RS22840	COG1309	transcriptional regulator
HB763_RS22885	COG3206	protein involved in exopolysaccharide biosynthesis
HB763_RS22885	COG0489	protein tyrosine kinase activity
HB763_RS22900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HB763_RS22905	COG3842	ATPase activity
HB763_RS22915	COG1175	transmembrane transport
HB763_RS22920	COG3833	ABC-type maltose transport systems, permease component
HB763_RS22950	COG2354	Protein conserved in bacteria
HB763_RS22965	COG3217	Mosc domain protein beta barrel domain protein
HB763_RS22965	COG0633	Ferredoxin
HB763_RS22965	COG0633	Ferredoxin
HB763_RS22965	COG3217	Mosc domain protein beta barrel domain protein
HB763_RS22975	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HB763_RS23015	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HB763_RS23020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB763_RS23030	COG0848	biopolymer transport protein
HB763_RS23035	COG0811	peptide transport
HB763_RS23040	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HB763_RS23055	COG3721	Heme iron utilization protein
HB763_RS23060	COG0748	coenzyme F420 binding
HB763_RS23070	COG0784	Response regulator, receiver
HB763_RS23070	COG0835	chemotaxis
HB763_RS23075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB763_RS23080	COG0366	Alpha amylase catalytic
HB763_RS23115	COG0583	DNA-binding transcription factor activity
HB763_RS23135	COG0583	DNA-binding transcription factor activity
HB763_RS23155	COG2814	Major facilitator Superfamily
HB763_RS23165	COG4977	sequence-specific DNA binding
HB763_RS23170	COG0673	inositol 2-dehydrogenase activity
HB763_RS23175	COG2194	sulfuric ester hydrolase activity
HB763_RS23180	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HB763_RS23190	COG2205	protein histidine kinase activity
HB763_RS23195	COG0745	RESPONSE REGULATOR receiver
HB763_RS23200	COG4221	oxidoreductase activity
HB763_RS23215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB763_RS23235	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HB763_RS23245	COG2814	Major facilitator Superfamily
HB763_RS23260	COG1418	mRNA catabolic process
HB763_RS23275	COG0402	S-adenosylhomocysteine deaminase activity
HB763_RS23280	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HB763_RS23285	COG2239	Acts as a magnesium transporter
HB763_RS23290	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HB763_RS23295	COG1566	PFAM secretion protein HlyD family protein
HB763_RS23320	COG0745	RESPONSE REGULATOR receiver
HB763_RS23325	COG2205	protein histidine kinase activity
HB763_RS23335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB763_RS23340	COG0531	amino acid
HB763_RS23345	COG1522	sequence-specific DNA binding
HB763_RS23355	COG0583	DNA-binding transcription factor activity
HB763_RS23385	COG0673	inositol 2-dehydrogenase activity
HB763_RS23460	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB763_RS23465	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HB763_RS23475	COG1280	lysine exporter protein (LysE YggA)
HB763_RS23485	COG0183	Belongs to the thiolase family
HB763_RS23505	COG3005	denitrification pathway
HB763_RS23525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB763_RS23530	COG3850	Histidine kinase
HB763_RS23535	COG2197	response regulator
HB763_RS23550	COG2195	Cleaves the N-terminal amino acid of tripeptides
HB763_RS23575	COG0840	transmembrane signaling receptor activity
HB763_RS23585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB763_RS23590	COG0545	Peptidyl-prolyl cis-trans isomerase
HB763_RS23620	COG1278	Cold shock
HB763_RS23625	COG3036	rescue of stalled ribosome
HB763_RS23635	COG2199	diguanylate cyclase activity
HB763_RS23650	COG1136	(ABC) transporter
HB763_RS23650	COG0577	efflux transmembrane transporter activity
HB763_RS23655	COG0577	efflux transmembrane transporter activity
HB763_RS23655	COG1136	(ABC) transporter
HB763_RS23665	COG0840	transmembrane signaling receptor activity
HB763_RS23670	COG0783	Belongs to the Dps family
HB763_RS23680	COG1619	proteins homologs of microcin C7 resistance protein MccF
HB763_RS23685	COG2133	pyrroloquinoline quinone binding
HB763_RS23690	COG1454	alcohol dehydrogenase
HB763_RS23695	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HB763_RS23720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB763_RS23730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HB763_RS23735	COG3186	Phenylalanine-4-hydroxylase
HB763_RS23765	COG3530	Putative quorum-sensing-regulated virulence factor
HB763_RS23790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HB763_RS23795	COG1845	cytochrome c oxidase, subunit III
HB763_RS23800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HB763_RS23805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HB763_RS23820	COG0454	-acetyltransferase
HB763_RS23855	COG0523	cobalamin synthesis protein
HB763_RS23860	COG3447	MASE1 domain protein
HB763_RS23860	COG5002	protein histidine kinase activity
HB763_RS23860	COG5001	Diguanylate cyclase
HB763_RS23865	COG0513	Belongs to the DEAD box helicase family
HB763_RS23885	COG2200	EAL domain
HB763_RS23890	COG1119	ATPase activity
HB763_RS23905	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HB763_RS23920	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
HB763_RS23925	COG0513	Belongs to the DEAD box helicase family
HB763_RS23935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HB763_RS23950	COG3278	Belongs to the heme-copper respiratory oxidase family
HB763_RS23990	COG1024	Enoyl-CoA hydratase
HB763_RS23995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HB763_RS24000	COG1960	acyl-CoA dehydrogenase activity
HB763_RS24010	COG0183	Belongs to the thiolase family
HB763_RS24025	COG1024	Enoyl-CoA hydratase
HB763_RS24030	COG1024	Enoyl-CoA hydratase
HB763_RS24040	COG1028	Short-chain dehydrogenase reductase Sdr
HB763_RS24045	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HB763_RS24050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HB763_RS24055	COG1845	cytochrome c oxidase, subunit III
HB763_RS24060	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HB763_RS24070	COG1902	pentaerythritol trinitrate reductase activity
HB763_RS24070	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB763_RS24085	COG1012	belongs to the aldehyde dehydrogenase family
HB763_RS24095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB763_RS24130	COG1126	abc transporter atp-binding protein
HB763_RS24135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB763_RS24140	COG4215	(ABC) transporter
HB763_RS24145	COG4160	amino acid transport
HB763_RS24170	COG3385	transposase activity
HB763_RS24185	COG5002	protein histidine kinase activity
HB763_RS24190	COG2200	EAL domain
HB763_RS24235	COG0443	Heat shock 70 kDa protein
HB763_RS24265	COG1785	Belongs to the alkaline phosphatase family
HB763_RS24305	COG0814	amino acid
HB763_RS24315	COG0243	molybdopterin cofactor binding
HB763_RS24320	COG1648	precorrin-2 dehydrogenase activity
HB763_RS24320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HB763_RS24340	COG1116	anion transmembrane transporter activity
HB763_RS24340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB763_RS24345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB763_RS24350	COG1116	anion transmembrane transporter activity
HB763_RS24355	COG2146	nitrite reductase [NAD(P)H] activity
HB763_RS24355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HB763_RS24405	COG0739	heme binding
HB763_RS24415	COG3038	cytochrome b561
HB763_RS24435	COG3706	GGDEF domain
HB763_RS24520	COG2814	Major facilitator Superfamily
HB763_RS24535	COG2816	NAD+ diphosphatase activity
HB763_RS24540	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HB763_RS24565	COG1132	(ABC) transporter
HB763_RS24580	COG3335	DDE superfamily endonuclease
HB763_RS24610	COG0583	DNA-binding transcription factor activity
HB763_RS24640	COG4772	TonB-dependent receptor
HB763_RS24645	COG1120	ATPase activity
HB763_RS24650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB763_RS24655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB763_RS24660	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HB763_RS24685	COG3335	DDE superfamily endonuclease
HB763_RS24710	COG3005	denitrification pathway
HB763_RS24825	COG0456	acetyltransferase
HB763_RS24850	COG0625	glutathione transferase activity
HB763_RS24875	COG2801	Transposase and inactivated derivatives
HB763_RS24890	COG0456	acetyltransferase
HB763_RS24940	COG2801	Transposase and inactivated derivatives
HB763_RS24995	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HB763_RS25005	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HB763_RS25020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB763_RS25035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB763_RS25035	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HB763_RS25035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB763_RS25040	COG1105	Belongs to the carbohydrate kinase PfkB family
HB763_RS25045	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB763_RS25045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB763_RS25050	COG1609	Transcriptional regulator
HB763_RS25065	COG2200	EAL domain
HB763_RS25065	COG2199	diguanylate cyclase activity
HB763_RS25065	COG2203	Gaf domain
HB763_RS25070	COG0765	amino acid transport
HB763_RS25075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB763_RS25080	COG0765	amino acid transport
HB763_RS25085	COG1126	abc transporter atp-binding protein
HB763_RS25095	COG1979	alcohol dehydrogenase
HB763_RS25100	COG2207	Transcriptional regulator
HB763_RS25110	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HB763_RS25175	COG1192	Involved in chromosome partitioning