locus-tag	class	description
BWP24_RS00015	COG2132	Multicopper oxidase
BWP24_RS00035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BWP24_RS00040	COG2104	thiamine diphosphate biosynthetic process
BWP24_RS00055	COG0006	proline dipeptidase activity
BWP24_RS00055	COG0006	proline dipeptidase activity
BWP24_RS00065	COG2814	Major facilitator Superfamily
BWP24_RS00085	COG3220	belongs to the UPF0276 family
BWP24_RS00095	COG0210	DNA helicase
BWP24_RS00105	COG0405	Gamma-glutamyltransferase
BWP24_RS00110	COG1280	lysine exporter protein (LysE YggA)
BWP24_RS00130	COG2962	Rard protein
BWP24_RS00135	COG0514	ATP-dependent DNA helicase (RecQ)
BWP24_RS00145	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BWP24_RS00160	COG3118	belongs to the thioredoxin family
BWP24_RS00175	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BWP24_RS00180	COG0633	Ferredoxin
BWP24_RS00220	COG3071	HemY protein
BWP24_RS00225	COG2959	enzyme of heme biosynthesis
BWP24_RS00230	COG1587	Uroporphyrinogen-III synthase
BWP24_RS00240	COG3072	Adenylate cyclase
BWP24_RS00255	COG0019	diaminopimelate decarboxylase activity
BWP24_RS00275	COG1011	Hydrolase
BWP24_RS00280	COG3287	FIST C domain
BWP24_RS00280	COG2200	EAL domain
BWP24_RS00280	COG2199	diguanylate cyclase activity
BWP24_RS00285	COG3148	PFAM DTW domain containing protein
BWP24_RS00300	COG0561	phosphatase activity
BWP24_RS00305	COG2267	carboxylic ester hydrolase activity
BWP24_RS00310	COG1280	lysine exporter protein (LysE YggA)
BWP24_RS00315	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BWP24_RS00320	COG0640	Transcriptional regulator
BWP24_RS00325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BWP24_RS00375	COG2095	MarC family integral membrane protein
BWP24_RS00385	COG0742	ribosomal rna small subunit methyltransferase
BWP24_RS00390	COG0552	protein localization to endoplasmic reticulum
BWP24_RS00390	COG0552	protein localization to endoplasmic reticulum
BWP24_RS00395	COG2884	Cell division ATP-binding protein ftsE
BWP24_RS00400	COG2177	Part of the ABC transporter FtsEX involved in
BWP24_RS00420	COG0705	Rhomboid family
BWP24_RS00425	COG1580	Controls the rotational direction of flagella during chemotaxis
BWP24_RS00430	COG3161	chorismate lyase activity
BWP24_RS00440	COG2937	Belongs to the GPAT DAPAT family
BWP24_RS00460	COG0534	Mate efflux family protein
BWP24_RS00465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWP24_RS00540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BWP24_RS00550	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BWP24_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BWP24_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
BWP24_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BWP24_RS00635	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BWP24_RS00640	COG2816	NAD+ diphosphatase activity
BWP24_RS00660	COG1573	uracil-dna glycosylase
BWP24_RS00670	COG3068	Protein conserved in bacteria
BWP24_RS00675	COG1253	flavin adenine dinucleotide binding
BWP24_RS00690	COG0151	Belongs to the GarS family
BWP24_RS00700	COG0789	Transcriptional regulator
BWP24_RS00705	COG3710	Transcriptional regulator
BWP24_RS00720	COG0531	amino acid
BWP24_RS00725	COG1982	Orn Lys Arg decarboxylase major
BWP24_RS00820	COG2199	diguanylate cyclase activity
BWP24_RS00825	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BWP24_RS00830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BWP24_RS00840	COG0439	Biotin carboxylase
BWP24_RS00845	COG0511	ligase activity, forming carbon-carbon bonds
BWP24_RS00850	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BWP24_RS00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BWP24_RS00870	COG2814	Major facilitator Superfamily
BWP24_RS00875	COG0784	Response regulator, receiver
BWP24_RS00875	COG2198	Histidine kinase
BWP24_RS00875	COG2205	protein histidine kinase activity
BWP24_RS00895	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BWP24_RS00905	COG2095	MarC family integral membrane protein
BWP24_RS00915	COG4232	protein-disulfide reductase activity
BWP24_RS00920	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BWP24_RS00925	COG1027	Aspartate ammonia-lyase
BWP24_RS00930	COG3030	protein affecting phage T7 exclusion by the F plasmid
BWP24_RS00935	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BWP24_RS00945	COG2205	protein histidine kinase activity
BWP24_RS00950	COG0745	RESPONSE REGULATOR receiver
BWP24_RS00970	COG0534	Mate efflux family protein
BWP24_RS00995	COG1509	lysine 2,3-aminomutase activity
BWP24_RS01025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BWP24_RS01030	COG1053	succinate dehydrogenase
BWP24_RS01055	COG4942	peptidase
BWP24_RS01060	COG1045	serine acetyltransferase
BWP24_RS01075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWP24_RS01080	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BWP24_RS01090	COG0840	transmembrane signaling receptor activity
BWP24_RS01095	COG0471	metal ion transport
BWP24_RS01105	COG1162	GTPase activity
BWP24_RS01180	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BWP24_RS01185	COG0802	atpase or kinase
BWP24_RS01190	COG0860	N-Acetylmuramoyl-L-alanine amidase
BWP24_RS01195	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BWP24_RS01210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BWP24_RS01215	COG0330	HflC and HflK could
BWP24_RS01220	COG0330	HflC and HflK could
BWP24_RS01225	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BWP24_RS01230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BWP24_RS01235	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BWP24_RS01240	COG1017	nitric oxide dioxygenase activity
BWP24_RS01240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BWP24_RS01250	COG0557	exoribonuclease II activity
BWP24_RS01255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BWP24_RS01260	COG0546	phosphoglycolate phosphatase activity
BWP24_RS01280	COG0512	Glutamine amidotransferase of anthranilate synthase
BWP24_RS01285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BWP24_RS01305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BWP24_RS01310	COG3954	Phosphoribulokinase
BWP24_RS01320	COG0429	hydrolase of the alpha beta-hydrolase fold
BWP24_RS01330	COG0488	(ABC) transporter
BWP24_RS01335	COG2249	NAD(P)H dehydrogenase (quinone) activity
BWP24_RS01350	COG1047	Peptidyl-prolyl cis-trans
BWP24_RS01355	COG1446	asparaginase
BWP24_RS01370	COG0545	Peptidyl-prolyl cis-trans isomerase
BWP24_RS01375	COG2964	Protein conserved in bacteria
BWP24_RS01380	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BWP24_RS01385	COG2923	Belongs to the DsrF TusC family
BWP24_RS01390	COG2168	tRNA wobble position uridine thiolation
BWP24_RS01405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BWP24_RS01415	COG2906	2 iron, 2 sulfur cluster binding
BWP24_RS01425	COG0281	malic enzyme
BWP24_RS01435	COG0626	cystathionine gamma-synthase activity
BWP24_RS01440	COG0460	homoserine dehydrogenase
BWP24_RS01440	COG0527	aspartate kinase activity
BWP24_RS01445	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BWP24_RS01455	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BWP24_RS01465	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BWP24_RS01480	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BWP24_RS01480	COG0165	Argininosuccinate lyase
BWP24_RS01490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWP24_RS01495	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BWP24_RS01495	COG0678	peroxiredoxin activity
BWP24_RS01505	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BWP24_RS01550	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BWP24_RS01555	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BWP24_RS01565	COG2965	DNA replication, synthesis of RNA primer
BWP24_RS01585	COG0305	Participates in initiation and elongation during chromosome replication
BWP24_RS01590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BWP24_RS01600	COG0432	Pfam Uncharacterised protein family UPF0047
BWP24_RS01615	COG0735	belongs to the Fur family
BWP24_RS01620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BWP24_RS01640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BWP24_RS01710	COG1410	methionine synthase
BWP24_RS01710	COG0646	methionine synthase
BWP24_RS01715	COG0527	aspartate kinase activity
BWP24_RS01725	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BWP24_RS01735	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BWP24_RS01750	COG0629	single-stranded DNA binding
BWP24_RS01755	COG2200	EAL domain
BWP24_RS01755	COG2199	diguanylate cyclase activity
BWP24_RS01780	COG3267	Type II secretory pathway component ExeA
BWP24_RS01780	COG3409	Peptidoglycan-binding domain 1 protein
BWP24_RS01790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BWP24_RS01795	COG1459	type II secretion system
BWP24_RS01805	COG2165	general secretion pathway protein
BWP24_RS01820	COG2165	general secretion pathway protein
BWP24_RS01840	COG1077	Cell shape determining protein MreB Mrl
BWP24_RS01845	COG1792	Involved in formation and maintenance of cell shape
BWP24_RS01850	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BWP24_RS01855	COG0424	maF-like protein
BWP24_RS01865	COG3164	Protein of unknown function
BWP24_RS01870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BWP24_RS01875	COG0312	modulator of DNA gyrase
BWP24_RS01880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BWP24_RS01895	COG0564	pseudouridine synthase activity
BWP24_RS01900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BWP24_RS01910	COG0312	modulator of DNA gyrase
BWP24_RS01915	COG2239	Acts as a magnesium transporter
BWP24_RS01920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWP24_RS01930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWP24_RS01935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BWP24_RS01945	COG1137	ATPase activity
BWP24_RS01950	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BWP24_RS01960	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BWP24_RS01960	COG0517	IMP dehydrogenase activity
BWP24_RS01970	COG1127	ABC transporter
BWP24_RS01975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BWP24_RS01980	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BWP24_RS01985	COG2854	intermembrane phospholipid transfer
BWP24_RS01995	COG5007	Belongs to the BolA IbaG family
BWP24_RS02005	COG0204	Acyl-transferase
BWP24_RS02010	COG0251	oxidation-reduction process
BWP24_RS02050	COG0456	acetyltransferase
BWP24_RS02060	COG0525	valine-tRNA ligase activity
BWP24_RS02065	COG2927	DNA polymerase III (CHI subunit)
BWP24_RS02075	COG0795	lipopolysaccharide-transporting ATPase activity
BWP24_RS02080	COG0795	lipopolysaccharide-transporting ATPase activity
BWP24_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
BWP24_RS02100	COG0726	polysaccharide deacetylase
BWP24_RS02105	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BWP24_RS02115	COG1447	Phosphotransferase system cellobiose-specific component IIA
BWP24_RS02120	COG1486	melibiose metabolic process
BWP24_RS02130	COG1609	Transcriptional regulator
BWP24_RS02185	COG1012	belongs to the aldehyde dehydrogenase family
BWP24_RS02285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BWP24_RS02290	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BWP24_RS02305	COG0762	integral membrane protein
BWP24_RS02310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BWP24_RS02315	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BWP24_RS02330	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BWP24_RS02335	COG1678	Uncharacterized ACR, COG1678
BWP24_RS02340	COG0189	ligase activity
BWP24_RS02345	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BWP24_RS02350	COG2356	endonuclease I
BWP24_RS02370	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BWP24_RS02390	COG0191	fructose-bisphosphate aldolase activity
BWP24_RS02395	COG0668	transmembrane transport
BWP24_RS02410	COG0583	DNA-binding transcription factor activity
BWP24_RS02420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BWP24_RS02430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BWP24_RS02440	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BWP24_RS02450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWP24_RS02455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWP24_RS02475	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BWP24_RS02485	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BWP24_RS02490	COG1595	DNA-templated transcription, initiation
BWP24_RS02505	COG3086	response to oxidative stress
BWP24_RS02525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BWP24_RS02530	COG1381	Involved in DNA repair and RecF pathway recombination
BWP24_RS02535	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BWP24_RS02560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BWP24_RS02565	COG3956	TIGRFAM MazG family protein
BWP24_RS02575	COG0148	phosphopyruvate hydratase activity
BWP24_RS02585	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BWP24_RS02615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BWP24_RS02625	COG1546	Belongs to the CinA family
BWP24_RS02630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BWP24_RS02645	COG0527	aspartate kinase activity
BWP24_RS02705	COG3630	sodium ion export across plasma membrane
BWP24_RS02710	COG0511	ligase activity, forming carbon-carbon bonds
BWP24_RS02710	COG5016	pyruvate
BWP24_RS02715	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BWP24_RS02725	COG1238	metal cluster binding
BWP24_RS02730	COG0612	Peptidase, M16
BWP24_RS02750	COG4536	flavin adenine dinucleotide binding
BWP24_RS02755	COG4137	Cytochrome C assembly protein
BWP24_RS02760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BWP24_RS02785	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BWP24_RS02790	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BWP24_RS02795	COG0237	dephospho-CoA kinase activity
BWP24_RS02805	COG1459	type II secretion system
BWP24_RS02810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BWP24_RS02835	COG2186	Transcriptional regulator
BWP24_RS02840	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BWP24_RS02845	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWP24_RS02850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWP24_RS02870	COG0288	reversible hydration of carbon dioxide
BWP24_RS02875	COG0659	secondary active sulfate transmembrane transporter activity
BWP24_RS02880	COG1131	(ABC) transporter
BWP24_RS02885	COG0842	Transport permease protein
BWP24_RS02890	COG1560	Kdo2-lipid A biosynthetic process
BWP24_RS02905	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BWP24_RS02915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BWP24_RS02930	COG1643	Atp-dependent helicase
BWP24_RS02935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BWP24_RS02940	COG1752	Esterase of the alpha-beta hydrolase superfamily
BWP24_RS02945	COG1049	propionate catabolic process, 2-methylcitrate cycle
BWP24_RS02960	COG0004	ammonium transporteR
BWP24_RS02965	COG1840	ABC-type Fe3 transport system, periplasmic component
BWP24_RS02975	COG3842	ATPase activity
BWP24_RS02980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BWP24_RS02995	COG2971	BadF BadG BcrA BcrD
BWP24_RS03005	COG4608	Belongs to the ABC transporter superfamily
BWP24_RS03010	COG0444	Belongs to the ABC transporter superfamily
BWP24_RS03015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWP24_RS03025	COG0747	negative chemotaxis
BWP24_RS03030	COG2205	protein histidine kinase activity
BWP24_RS03030	COG2198	Histidine kinase
BWP24_RS03030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWP24_RS03030	COG0784	Response regulator, receiver
BWP24_RS03045	COG0628	permease
BWP24_RS03065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWP24_RS03070	COG0739	heme binding
BWP24_RS03075	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BWP24_RS03090	COG2027	D-alanyl-D-alanine carboxypeptidase
BWP24_RS03095	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BWP24_RS03100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BWP24_RS03105	COG1534	Rna-binding protein
BWP24_RS03115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BWP24_RS03120	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BWP24_RS03135	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BWP24_RS03155	COG0195	Participates in both transcription termination and antitermination
BWP24_RS03175	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BWP24_RS03195	COG0534	Mate efflux family protein
BWP24_RS03200	COG0826	peptidase U32
BWP24_RS03205	COG0826	peptidase U32
BWP24_RS03215	COG3154	lipid carrier protein
BWP24_RS03220	COG3153	acetyltransferase
BWP24_RS03240	COG3706	GGDEF domain
BWP24_RS03250	COG0084	hydrolase, TatD family'
BWP24_RS03255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWP24_RS03265	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BWP24_RS03275	COG0813	purine-nucleoside phosphorylase activity
BWP24_RS03285	COG0560	Phosphoserine phosphatase
BWP24_RS03295	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BWP24_RS03300	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BWP24_RS03305	COG0583	DNA-binding transcription factor activity
BWP24_RS03340	COG1022	Amp-dependent synthetase and ligase
BWP24_RS03365	COG4964	Belongs to the GSP D family
BWP24_RS03425	COG0583	DNA-binding transcription factor activity
BWP24_RS03430	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BWP24_RS03430	COG3408	Glycogen debranching enzyme
BWP24_RS03440	COG0531	amino acid
BWP24_RS03445	COG2731	YhcH YjgK YiaL family protein
BWP24_RS03450	COG3250	beta-galactosidase activity
BWP24_RS03455	COG1609	Transcriptional regulator
BWP24_RS03460	COG0768	penicillin binding
BWP24_RS03465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BWP24_RS03470	COG1085	galactose-1-phosphate uridylyltransferase
BWP24_RS03480	COG2017	converts alpha-aldose to the beta-anomer
BWP24_RS03490	COG1609	Transcriptional regulator
BWP24_RS03495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWP24_RS03495	COG1263	PTS System
BWP24_RS03505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWP24_RS03530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BWP24_RS03535	COG1349	DNA-binding transcription factor activity
BWP24_RS03545	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BWP24_RS03550	COG2271	Major facilitator Superfamily
BWP24_RS03555	COG0584	glycerophosphoryl diester phosphodiesterase
BWP24_RS03570	COG2171	N-acyltransferase activity
BWP24_RS03585	COG3141	response to X-ray
BWP24_RS03605	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BWP24_RS03610	COG1074	ATP-dependent DNA helicase activity
BWP24_RS03615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BWP24_RS03635	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BWP24_RS03635	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BWP24_RS03650	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BWP24_RS03655	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BWP24_RS03660	COG2166	iron-sulfur cluster assembly
BWP24_RS03665	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BWP24_RS03670	COG0693	protein deglycase activity
BWP24_RS03675	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BWP24_RS03695	COG1595	DNA-templated transcription, initiation
BWP24_RS03725	COG0271	Belongs to the BolA IbaG family
BWP24_RS03760	COG1477	protein flavinylation
BWP24_RS03775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BWP24_RS03780	COG0514	ATP-dependent DNA helicase (RecQ)
BWP24_RS03785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BWP24_RS03800	COG0733	neurotransmitter:sodium symporter activity
BWP24_RS03825	COG1720	tRNA m6t6A37 methyltransferase activity
BWP24_RS03840	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BWP24_RS03875	COG3098	single-species biofilm formation
BWP24_RS03880	COG0564	pseudouridine synthase activity
BWP24_RS03895	COG0024	Methionine aminopeptidase
BWP24_RS03920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BWP24_RS03925	COG0575	Belongs to the CDS family
BWP24_RS03935	COG0750	zinc metalloprotease
BWP24_RS03945	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BWP24_RS03950	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BWP24_RS03975	COG0587	DNA-directed DNA polymerase activity
BWP24_RS03995	COG0347	Belongs to the P(II) protein family
BWP24_RS04010	COG0741	lytic transglycosylase activity
BWP24_RS04010	COG1388	LysM domain
BWP24_RS04020	COG2226	methyltransferase
BWP24_RS04030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BWP24_RS04055	COG1960	acyl-CoA dehydrogenase activity
BWP24_RS04060	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BWP24_RS04065	COG0121	glutamine amidotransferase
BWP24_RS04070	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BWP24_RS04075	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BWP24_RS04080	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BWP24_RS04085	COG2233	PERMEase
BWP24_RS04105	COG1393	Belongs to the ArsC family
BWP24_RS04110	COG4783	chaperone-mediated protein folding
BWP24_RS04125	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BWP24_RS04130	COG2716	regulation of RNA biosynthetic process
BWP24_RS04135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BWP24_RS04140	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BWP24_RS04160	COG1393	Belongs to the ArsC family
BWP24_RS04190	COG2837	iron assimilation
BWP24_RS04195	COG2169	Transcriptional regulator
BWP24_RS04200	COG1486	melibiose metabolic process
BWP24_RS04205	COG2211	Major facilitator Superfamily
BWP24_RS04215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWP24_RS04225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWP24_RS04230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWP24_RS04235	COG1334	flagellar protein FlaG
BWP24_RS04240	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BWP24_RS04250	COG1516	flagellar protein fliS
BWP24_RS04270	COG1677	Flagellar hook-basal body complex protein FliE
BWP24_RS04280	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BWP24_RS04335	COG1987	bacterial-type flagellum assembly
BWP24_RS04340	COG1684	flagellar biosynthetic protein fliR
BWP24_RS04375	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BWP24_RS04380	COG0784	Response regulator, receiver
BWP24_RS04380	COG0643	Histidine kinase
BWP24_RS04380	COG2198	Histidine kinase
BWP24_RS04385	COG2201	protein-glutamate methylesterase activity
BWP24_RS04390	COG1192	Involved in chromosome partitioning
BWP24_RS04400	COG0835	chemotaxis
BWP24_RS04410	COG4133	protoheme IX ABC transporter activity
BWP24_RS04415	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BWP24_RS04420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BWP24_RS04435	COG1138	Cytochrome C-type biogenesis protein
BWP24_RS04440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWP24_RS04450	COG3088	subunit of a heme lyase
BWP24_RS04450	COG4235	cytochrome complex assembly
BWP24_RS04455	COG2853	Lipoprotein
BWP24_RS04465	COG2067	long-chain fatty acid transport protein
BWP24_RS04485	COG0183	Belongs to the thiolase family
BWP24_RS04505	COG2062	phosphohistidine phosphatase, SixA
BWP24_RS04515	COG2890	protein-(glutamine-N5) methyltransferase activity
BWP24_RS04525	COG2860	membrane
BWP24_RS04530	COG3101	peptidyl-lysine hydroxylation
BWP24_RS04555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BWP24_RS04565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BWP24_RS04570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BWP24_RS04595	COG0285	dihydrofolate synthase activity
BWP24_RS04600	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BWP24_RS04605	COG1286	toxin biosynthetic process
BWP24_RS04610	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BWP24_RS04615	COG0583	DNA-binding transcription factor activity
BWP24_RS04620	COG0745	RESPONSE REGULATOR receiver
BWP24_RS04625	COG2832	Protein of unknown function (DUF454)
BWP24_RS04635	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BWP24_RS04645	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BWP24_RS04650	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BWP24_RS04655	COG0814	amino acid
BWP24_RS04660	COG0251	oxidation-reduction process
BWP24_RS04670	COG2964	Protein conserved in bacteria
BWP24_RS04680	COG2983	Belongs to the UPF0260 family
BWP24_RS04685	COG2261	transglycosylase associated protein
BWP24_RS04690	COG2985	domain, Protein
BWP24_RS04695	COG0076	glutamate decarboxylase activity
BWP24_RS04700	COG0668	transmembrane transport
BWP24_RS04710	COG0346	lactoylglutathione lyase activity
BWP24_RS04720	COG1785	Belongs to the alkaline phosphatase family
BWP24_RS04740	COG2226	methyltransferase
BWP24_RS04760	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BWP24_RS04765	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWP24_RS04775	COG3139	Protein of unknown function (DUF1315)
BWP24_RS04780	COG0252	asparaginase activity
BWP24_RS04785	COG0616	signal peptide processing
BWP24_RS04790	COG0446	pyridine nucleotide-disulphide oxidoreductase
BWP24_RS04790	COG1902	pentaerythritol trinitrate reductase activity
BWP24_RS04795	COG0778	Nitroreductase
BWP24_RS04800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BWP24_RS04815	COG0123	including yeast histone deacetylase and acetoin utilization protein
BWP24_RS04825	COG4269	membrane
BWP24_RS04840	COG3083	sulfuric ester hydrolase activity
BWP24_RS04865	COG1757	Na H antiporter
BWP24_RS04870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BWP24_RS04875	COG2165	general secretion pathway protein
BWP24_RS04880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BWP24_RS04885	COG2095	MarC family integral membrane protein
BWP24_RS04890	COG1012	belongs to the aldehyde dehydrogenase family
BWP24_RS04890	COG1454	alcohol dehydrogenase
BWP24_RS04895	COG1028	Short-chain dehydrogenase reductase Sdr
BWP24_RS04910	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BWP24_RS04915	COG4974	Belongs to the 'phage' integrase family
BWP24_RS04935	COG1403	HNH endonuclease
BWP24_RS05095	COG3504	Conjugal transfer protein
BWP24_RS05100	COG3736	Type IV secretory pathway, component VirB8
BWP24_RS05120	COG3451	type IV secretory pathway VirB4
BWP24_RS05155	COG2056	Na+-H+ antiporter family
BWP24_RS05165	COG2885	chlorophyll binding
BWP24_RS05175	COG0346	lactoylglutathione lyase activity
BWP24_RS05180	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BWP24_RS05185	COG4660	Part of a membrane complex involved in electron transport
BWP24_RS05190	COG4659	FMN binding
BWP24_RS05195	COG4658	electron transport chain
BWP24_RS05200	COG4656	Part of a membrane complex involved in electron transport
BWP24_RS05210	COG4657	Part of a membrane complex involved in electron transport
BWP24_RS05215	COG1882	Formate acetyltransferase
BWP24_RS05220	COG0745	RESPONSE REGULATOR receiver
BWP24_RS05255	COG0556	nucleotide-excision repair
BWP24_RS05270	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BWP24_RS05275	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BWP24_RS05280	COG0521	Mo-molybdopterin cofactor biosynthetic process
BWP24_RS05290	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BWP24_RS05295	COG0314	molybdopterin synthase activity
BWP24_RS05305	COG0601	transmembrane transport
BWP24_RS05310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWP24_RS05315	COG0444	Belongs to the ABC transporter superfamily
BWP24_RS05325	COG0435	Glutathione S-transferase
BWP24_RS05330	COG3174	membrane
BWP24_RS05335	COG0857	belongs to the CobB CobQ family
BWP24_RS05335	COG0280	phosphate acetyltransferase
BWP24_RS05360	COG4120	Belongs to the binding-protein-dependent transport system permease family
BWP24_RS05365	COG1122	ATPase activity
BWP24_RS05370	COG0366	Alpha amylase catalytic
BWP24_RS05380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BWP24_RS05385	COG0653	protein targeting
BWP24_RS05390	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BWP24_RS05400	COG2186	Transcriptional regulator
BWP24_RS05430	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BWP24_RS05435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BWP24_RS05440	COG0659	secondary active sulfate transmembrane transporter activity
BWP24_RS05450	COG1530	ribonuclease E activity
BWP24_RS05455	COG0564	pseudouridine synthase activity
BWP24_RS05460	COG0424	maF-like protein
BWP24_RS05465	COG1399	metal-binding, possibly nucleic acid-binding protein
BWP24_RS05480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BWP24_RS05510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BWP24_RS05525	COG0084	hydrolase, TatD family'
BWP24_RS05530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWP24_RS05530	COG1263	PTS System
BWP24_RS05540	COG0733	neurotransmitter:sodium symporter activity
BWP24_RS05550	COG4667	esterase of the alpha-beta hydrolase superfamily
BWP24_RS05575	COG2272	Belongs to the type-B carboxylesterase lipase family
BWP24_RS05585	COG3710	Transcriptional regulator
BWP24_RS05600	COG1940	carbohydrate kinase activity
BWP24_RS05605	COG0784	Response regulator, receiver
BWP24_RS05605	COG0835	chemotaxis
BWP24_RS05625	COG1028	Short-chain dehydrogenase reductase Sdr
BWP24_RS05630	COG0616	signal peptide processing
BWP24_RS05640	COG0539	negative regulation of cytoplasmic translation
BWP24_RS05650	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BWP24_RS05655	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BWP24_RS05665	COG4166	transmembrane transport
BWP24_RS05685	COG3009	Protein conserved in bacteria
BWP24_RS05690	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BWP24_RS05690	COG3008	intermembrane lipid transfer
BWP24_RS05695	COG2995	paraquat-inducible protein a
BWP24_RS05710	COG4232	protein-disulfide reductase activity
BWP24_RS05715	COG3118	belongs to the thioredoxin family
BWP24_RS05725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BWP24_RS05755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWP24_RS05765	COG0577	efflux transmembrane transporter activity
BWP24_RS05770	COG0577	efflux transmembrane transporter activity
BWP24_RS05770	COG1136	(ABC) transporter
BWP24_RS05775	COG1136	(ABC) transporter
BWP24_RS05775	COG0577	efflux transmembrane transporter activity
BWP24_RS05790	COG2176	DNA-directed DNA polymerase activity
BWP24_RS05850	COG0515	serine threonine protein kinase
BWP24_RS05855	COG3850	Histidine kinase
BWP24_RS05855	COG5002	protein histidine kinase activity
BWP24_RS05860	COG0745	RESPONSE REGULATOR receiver
BWP24_RS05865	COG0463	Glycosyl transferase, family 2
BWP24_RS05870	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BWP24_RS05880	COG0840	transmembrane signaling receptor activity
BWP24_RS05885	COG2175	clavaminate synthase activity
BWP24_RS05890	COG2964	Protein conserved in bacteria
BWP24_RS05905	COG0446	pyridine nucleotide-disulphide oxidoreductase
BWP24_RS05925	COG1032	radical SAM domain protein
BWP24_RS05930	COG1716	ATPase activity
BWP24_RS05930	COG5001	Diguanylate cyclase
BWP24_RS05960	COG2350	Protein conserved in bacteria
BWP24_RS05990	COG1301	dicarboxylic acid transport
BWP24_RS05995	COG0159	tryptophan synthase activity
BWP24_RS06005	COG0135	phosphoribosylanthranilate isomerase activity
BWP24_RS06005	COG0134	indole-3-glycerol-phosphate synthase activity
BWP24_RS06015	COG0512	Glutamine amidotransferase of anthranilate synthase
BWP24_RS06020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BWP24_RS06030	COG0613	PHP domain protein
BWP24_RS06035	COG0009	L-threonylcarbamoyladenylate synthase
BWP24_RS06045	COG1187	pseudouridine synthase activity
BWP24_RS06065	COG0417	DNA replication proofreading
BWP24_RS06070	COG2197	response regulator
BWP24_RS06075	COG0322	excinuclease ABC activity
BWP24_RS06120	COG0019	diaminopimelate decarboxylase activity
BWP24_RS06135	COG1058	Belongs to the CinA family
BWP24_RS06135	COG1546	Belongs to the CinA family
BWP24_RS06145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BWP24_RS06150	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BWP24_RS06175	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BWP24_RS06185	COG0437	4 iron, 4 sulfur cluster binding
BWP24_RS06190	COG3301	Polysulphide reductase, NrfD
BWP24_RS06195	COG1138	Cytochrome C-type biogenesis protein
BWP24_RS06205	COG4235	cytochrome complex assembly
BWP24_RS06205	COG3088	subunit of a heme lyase
BWP24_RS06240	COG2989	Protein conserved in bacteria
BWP24_RS06245	COG3108	Peptidase M15
BWP24_RS06250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWP24_RS06265	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BWP24_RS06290	COG1846	Transcriptional regulator
BWP24_RS06295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BWP24_RS06320	COG1448	Aminotransferase
BWP24_RS06325	COG3437	response regulator, receiver
BWP24_RS06325	COG2770	Histidine kinase
BWP24_RS06340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWP24_RS06355	COG0017	Asparaginyl-tRNA synthetase
BWP24_RS06365	COG0720	synthase
BWP24_RS06370	COG2197	response regulator
BWP24_RS06385	COG1760	l-serine dehydratase
BWP24_RS06390	COG0814	amino acid
BWP24_RS06405	COG0784	Response regulator, receiver
BWP24_RS06405	COG2205	protein histidine kinase activity
BWP24_RS06410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BWP24_RS06425	COG3106	COG3106 Predicted ATPase
BWP24_RS06440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWP24_RS06580	COG0519	Catalyzes the synthesis of GMP from XMP
BWP24_RS07240	COG0494	nUDIX hydrolase
BWP24_RS07245	COG1714	RDD family
BWP24_RS07270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BWP24_RS07450	COG4221	oxidoreductase activity
BWP24_RS07465	COG3340	Belongs to the peptidase S51 family
BWP24_RS07495	COG0456	acetyltransferase
BWP24_RS07500	COG0471	metal ion transport
BWP24_RS07505	COG4191	Histidine kinase
BWP24_RS07505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWP24_RS07530	COG1328	CTP reductase activity
BWP24_RS07535	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BWP24_RS07545	COG0861	Integral membrane protein TerC family
BWP24_RS07555	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BWP24_RS07560	COG4221	oxidoreductase activity
BWP24_RS07565	COG1454	alcohol dehydrogenase
BWP24_RS07570	COG0814	amino acid
BWP24_RS07590	COG1132	(ABC) transporter
BWP24_RS07595	COG1132	(ABC) transporter
BWP24_RS07600	COG2165	general secretion pathway protein
BWP24_RS07605	COG0583	DNA-binding transcription factor activity
BWP24_RS07630	COG0443	Heat shock 70 kDa protein
BWP24_RS07635	COG0443	Heat shock 70 kDa protein
BWP24_RS07645	COG3706	GGDEF domain
BWP24_RS07675	COG3227	Zinc metalloprotease (Elastase)
BWP24_RS07695	COG3842	ATPase activity
BWP24_RS07700	COG3459	Glycosyltransferase 36 associated
BWP24_RS07710	COG1653	transport
BWP24_RS07720	COG0395	ABC-type sugar transport system, permease component
BWP24_RS07735	COG0243	molybdopterin cofactor binding
BWP24_RS07740	COG0437	4 iron, 4 sulfur cluster binding
BWP24_RS07745	COG3302	dmso reductase anchor subunit
BWP24_RS07760	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BWP24_RS07765	COG1643	Atp-dependent helicase
BWP24_RS07790	COG3063	Type IV pilus biogenesis stability protein PilW
BWP24_RS07820	COG0531	amino acid
BWP24_RS07825	COG1280	lysine exporter protein (LysE YggA)
BWP24_RS07830	COG1560	Kdo2-lipid A biosynthetic process
BWP24_RS07850	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BWP24_RS07855	COG1280	lysine exporter protein (LysE YggA)
BWP24_RS07890	COG1115	amino acid carrier protein
BWP24_RS07910	COG1368	sulfuric ester hydrolase activity
BWP24_RS07925	COG0215	cysteine-tRNA ligase activity
BWP24_RS07930	COG0534	Mate efflux family protein
BWP24_RS07935	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BWP24_RS07945	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BWP24_RS07950	COG0456	acetyltransferase
BWP24_RS07955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BWP24_RS07960	COG0662	Cupin 2, conserved barrel domain protein
BWP24_RS07965	COG0527	aspartate kinase activity
BWP24_RS07975	COG1858	cytochrome C peroxidase
BWP24_RS07980	COG1404	Belongs to the peptidase S8 family
BWP24_RS07985	COG3227	Zinc metalloprotease (Elastase)
BWP24_RS08000	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BWP24_RS08005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BWP24_RS08010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BWP24_RS08035	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BWP24_RS08040	COG0667	Aldo Keto reductase
BWP24_RS08055	COG0583	DNA-binding transcription factor activity
BWP24_RS08060	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BWP24_RS08065	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BWP24_RS08070	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BWP24_RS08075	COG0679	Auxin Efflux Carrier
BWP24_RS08115	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BWP24_RS08150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWP24_RS08165	COG3290	protein histidine kinase activity
BWP24_RS08170	COG4565	transcriptional regulatory protein
BWP24_RS08175	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BWP24_RS08180	COG0363	glucosamine-6-phosphate deaminase activity
BWP24_RS08185	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BWP24_RS08215	COG3284	Transcriptional regulator
BWP24_RS08220	COG1012	belongs to the aldehyde dehydrogenase family
BWP24_RS08225	COG2358	TRAP transporter, solute receptor (TAXI family
BWP24_RS08230	COG0730	response to heat
BWP24_RS08260	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BWP24_RS08265	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BWP24_RS08375	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BWP24_RS08380	COG0372	Belongs to the citrate synthase family
BWP24_RS08390	COG2828	Protein conserved in bacteria
BWP24_RS08405	COG3119	arylsulfatase activity
BWP24_RS08425	COG0561	phosphatase activity
BWP24_RS08430	COG0602	queuosine metabolic process
BWP24_RS08440	COG3706	GGDEF domain
BWP24_RS08490	COG0840	transmembrane signaling receptor activity
BWP24_RS08495	COG1254	Belongs to the acylphosphatase family
BWP24_RS08500	COG2920	part of a sulfur-relay system
BWP24_RS08510	COG0670	Belongs to the BI1 family
BWP24_RS08515	COG1126	abc transporter atp-binding protein
BWP24_RS08520	COG0765	amino acid transport
BWP24_RS08525	COG4597	amino acid ABC transporter
BWP24_RS08530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWP24_RS08545	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BWP24_RS08570	COG3008	intermembrane lipid transfer
BWP24_RS08575	COG2995	paraquat-inducible protein a
BWP24_RS08580	COG1132	(ABC) transporter
BWP24_RS08585	COG1956	GAF domain-containing protein
BWP24_RS08590	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BWP24_RS08605	COG0308	aminopeptidase N
BWP24_RS08615	COG2902	Dehydrogenase
BWP24_RS08640	COG0488	(ABC) transporter
BWP24_RS08665	COG1067	ATP-dependent peptidase activity
BWP24_RS08695	COG2801	Transposase and inactivated derivatives
BWP24_RS08700	COG2205	protein histidine kinase activity
BWP24_RS08700	COG0784	Response regulator, receiver
BWP24_RS08715	COG3278	Belongs to the heme-copper respiratory oxidase family
BWP24_RS08730	COG2010	Cytochrome c
BWP24_RS08740	COG2217	Heavy metal translocating P-type atpase
BWP24_RS08755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BWP24_RS08760	COG0589	response to stress
BWP24_RS08785	COG3842	ATPase activity
BWP24_RS08795	COG1177	transmembrane transport
BWP24_RS08805	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BWP24_RS08810	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BWP24_RS08830	COG0437	4 iron, 4 sulfur cluster binding
BWP24_RS08835	COG0243	molybdopterin cofactor binding
BWP24_RS08835	COG3383	formate dehydrogenase (NAD+) activity
BWP24_RS08845	COG3381	protein complex oligomerization
BWP24_RS08865	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BWP24_RS08880	COG0488	(ABC) transporter
BWP24_RS08895	COG4191	Histidine kinase
BWP24_RS08900	COG2204	response regulator
BWP24_RS08910	COG4662	Binding-protein-dependent transport system inner membrane component
BWP24_RS08915	COG3842	ATPase activity
BWP24_RS08925	COG0303	'Molybdopterin
BWP24_RS08935	COG1940	carbohydrate kinase activity
BWP24_RS08940	COG3148	PFAM DTW domain containing protein
BWP24_RS08990	COG0840	transmembrane signaling receptor activity
BWP24_RS08995	COG0791	NLP P60 protein
BWP24_RS09005	COG3706	GGDEF domain
BWP24_RS09010	COG2201	protein-glutamate methylesterase activity
BWP24_RS09015	COG3001	Fructosamine kinase
BWP24_RS09025	COG0307	riboflavin synthase, alpha
BWP24_RS09030	COG0534	Mate efflux family protein
BWP24_RS09040	COG1793	dna ligase
BWP24_RS09050	COG2885	chlorophyll binding
BWP24_RS09070	COG2204	response regulator
BWP24_RS09075	COG0438	transferase activity, transferring glycosyl groups
BWP24_RS09080	COG0438	transferase activity, transferring glycosyl groups
BWP24_RS09110	COG0438	transferase activity, transferring glycosyl groups
BWP24_RS09115	COG1215	transferase activity, transferring glycosyl groups
BWP24_RS09120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BWP24_RS09130	COG3064	Membrane
BWP24_RS09155	COG5001	Diguanylate cyclase
BWP24_RS09155	COG3300	MHYT domain
BWP24_RS09160	COG3437	response regulator, receiver
BWP24_RS09160	COG4999	Histidine kinase
BWP24_RS09160	COG3850	Histidine kinase
BWP24_RS09160	COG2205	protein histidine kinase activity
BWP24_RS09180	COG0110	maltose O-acetyltransferase activity
BWP24_RS09205	COG1846	Transcriptional regulator
BWP24_RS09215	COG1482	cell wall glycoprotein biosynthetic process
BWP24_RS09230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWP24_RS09250	COG0383	alpha-mannosidase activity
BWP24_RS09260	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BWP24_RS09285	COG3247	response to pH
BWP24_RS09290	COG0668	transmembrane transport
BWP24_RS09300	COG1404	Belongs to the peptidase S8 family
BWP24_RS09310	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BWP24_RS09325	COG0745	RESPONSE REGULATOR receiver
BWP24_RS09375	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BWP24_RS09375	COG2199	diguanylate cyclase activity
BWP24_RS09410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWP24_RS09425	COG0786	glutamate:sodium symporter activity
BWP24_RS09445	COG0625	glutathione transferase activity
BWP24_RS09455	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BWP24_RS09470	COG2195	Cleaves the N-terminal amino acid of tripeptides
BWP24_RS09500	COG0813	purine-nucleoside phosphorylase activity
BWP24_RS09525	COG1451	nucleotide metabolic process
BWP24_RS09535	COG5492	domain, Protein
BWP24_RS09535	COG4932	domain protein
BWP24_RS09550	COG0745	RESPONSE REGULATOR receiver
BWP24_RS09560	COG2205	protein histidine kinase activity
BWP24_RS09560	COG0784	Response regulator, receiver
BWP24_RS09620	COG2165	general secretion pathway protein
BWP24_RS09645	COG0583	DNA-binding transcription factor activity
BWP24_RS09675	COG4139	cobalamin transport
BWP24_RS09690	COG2062	phosphohistidine phosphatase, SixA
BWP24_RS09700	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BWP24_RS09710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BWP24_RS09715	COG0702	epimerase
BWP24_RS09720	COG1823	symporter activity
BWP24_RS09730	COG2925	Exonuclease
BWP24_RS09740	COG1346	cytolysis
BWP24_RS09790	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWP24_RS09795	COG4605	iron ion homeostasis
BWP24_RS09800	COG4607	ABC-type enterochelin transport system periplasmic component
BWP24_RS09805	COG4774	siderophore transport
BWP24_RS09825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BWP24_RS09840	COG1132	(ABC) transporter
BWP24_RS09845	COG1535	isochorismatase
BWP24_RS09845	COG3433	isochorismatase activity
BWP24_RS09850	COG0072	phenylalanine-tRNA ligase activity
BWP24_RS09850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWP24_RS09860	COG3706	GGDEF domain
BWP24_RS09900	COG0251	oxidation-reduction process
BWP24_RS09940	COG2188	Transcriptional regulator
BWP24_RS09950	COG0010	Belongs to the arginase family
BWP24_RS09960	COG2986	histidine ammonia-lyase
BWP24_RS10005	COG0247	lactate metabolic process
BWP24_RS10005	COG0277	FAD linked oxidase domain protein
BWP24_RS10065	COG1643	Atp-dependent helicase
BWP24_RS10075	COG2949	membrane
BWP24_RS10080	COG0471	metal ion transport
BWP24_RS10085	COG3706	GGDEF domain
BWP24_RS10105	COG0492	ferredoxin-NADP+ reductase activity
BWP24_RS10110	COG4988	ABC transporter
BWP24_RS10115	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BWP24_RS10125	COG2610	gluconate transmembrane transporter activity
BWP24_RS10130	COG0583	DNA-binding transcription factor activity
BWP24_RS10135	COG2200	EAL domain
BWP24_RS10165	COG5001	Diguanylate cyclase
BWP24_RS10180	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BWP24_RS10190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWP24_RS10190	COG4191	Histidine kinase
BWP24_RS10205	COG3070	regulator of competence-specific genes
BWP24_RS10215	COG2431	L-lysine efflux transmembrane transporter activity
BWP24_RS10225	COG0076	glutamate decarboxylase activity
BWP24_RS10230	COG1737	Transcriptional regulator
BWP24_RS10240	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BWP24_RS10250	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BWP24_RS10280	COG4181	ATPase activity
BWP24_RS10285	COG0534	Mate efflux family protein
BWP24_RS10290	COG0702	epimerase
BWP24_RS10295	COG4667	esterase of the alpha-beta hydrolase superfamily
BWP24_RS10305	COG2814	Major facilitator Superfamily
BWP24_RS10310	COG1187	pseudouridine synthase activity
BWP24_RS10315	COG1061	Type III restriction enzyme res subunit
BWP24_RS10335	COG2199	diguanylate cyclase activity
BWP24_RS10390	COG3313	Fe-S protein
BWP24_RS10400	COG0659	secondary active sulfate transmembrane transporter activity
BWP24_RS10425	COG0493	'glutamate synthase
BWP24_RS10435	COG0398	Pfam SNARE associated Golgi protein
BWP24_RS10440	COG4134	Bacterial extracellular solute-binding protein
BWP24_RS10445	COG4135	transport system, permease component
BWP24_RS10450	COG4136	ATPase activity
BWP24_RS10455	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BWP24_RS10465	COG2814	Major facilitator Superfamily
BWP24_RS10470	COG3604	Transcriptional regulator
BWP24_RS10475	COG1151	hydroxylamine reductase activity
BWP24_RS10480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BWP24_RS10490	COG0564	pseudouridine synthase activity
BWP24_RS10500	COG0733	neurotransmitter:sodium symporter activity
BWP24_RS10510	COG0626	cystathionine gamma-synthase activity
BWP24_RS10515	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BWP24_RS10535	COG2818	Glycosylase
BWP24_RS10555	COG1983	PspC domain protein
BWP24_RS10565	COG1842	Phage shock protein A
BWP24_RS10570	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BWP24_RS10580	COG4168	peptide transport system, permease
BWP24_RS10585	COG4171	peptide transport system, permease
BWP24_RS10595	COG4172	Belongs to the ABC transporter superfamily
BWP24_RS10605	COG1227	inorganic diphosphatase activity
BWP24_RS10620	COG0243	molybdopterin cofactor binding
BWP24_RS10625	COG3005	denitrification pathway
BWP24_RS10630	COG4459	periplasmic nitrate reductase
BWP24_RS10635	COG0390	transport system, permease component
BWP24_RS10640	COG2116	formate transmembrane transporter activity
BWP24_RS10665	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BWP24_RS10670	COG1435	thymidine kinase activity
BWP24_RS10675	COG0215	cysteine-tRNA ligase activity
BWP24_RS10680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BWP24_RS10685	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BWP24_RS10695	COG3012	SEC-C Motif Domain Protein
BWP24_RS10700	COG0140	phosphoribosyl-ATP diphosphatase activity
BWP24_RS10700	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BWP24_RS10710	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BWP24_RS10715	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BWP24_RS10720	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BWP24_RS10720	COG0131	Imidazoleglycerol-phosphate dehydratase
BWP24_RS10730	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BWP24_RS10745	COG1757	Na H antiporter
BWP24_RS10755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWP24_RS10775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BWP24_RS10795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BWP24_RS10810	COG0300	oxidoreductase activity
BWP24_RS10830	COG2226	methyltransferase
BWP24_RS10850	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BWP24_RS10870	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BWP24_RS10880	COG1674	ftsk spoiiie
BWP24_RS10890	COG0686	Belongs to the AlaDH PNT family
BWP24_RS10900	COG0583	DNA-binding transcription factor activity
BWP24_RS10925	COG0402	S-adenosylhomocysteine deaminase activity
BWP24_RS10930	COG4934	collagen metabolic process
BWP24_RS10950	COG3568	Endonuclease Exonuclease Phosphatase
BWP24_RS10970	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BWP24_RS10985	COG1288	antiporter activity
BWP24_RS10995	COG2186	Transcriptional regulator
BWP24_RS11005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWP24_RS11010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWP24_RS11040	COG0747	negative chemotaxis
BWP24_RS11045	COG4608	Belongs to the ABC transporter superfamily
BWP24_RS11050	COG0444	Belongs to the ABC transporter superfamily
BWP24_RS11055	COG0534	Mate efflux family protein
BWP24_RS11065	COG2824	Alkylphosphonate utilization operon protein PhnA
BWP24_RS11085	COG3119	arylsulfatase activity
BWP24_RS11125	COG0457	Tetratricopeptide repeat
BWP24_RS11195	COG4790	Type iii secretion
BWP24_RS11200	COG4794	Type iii secretion
BWP24_RS11205	COG4791	protein targeting
BWP24_RS11210	COG4792	protein secretion
BWP24_RS11225	COG3177	Filamentation induced by cAMP protein fic
BWP24_RS11255	COG4669	(LipO)protein
BWP24_RS11360	COG2205	protein histidine kinase activity
BWP24_RS11360	COG0784	Response regulator, receiver
BWP24_RS11370	COG0754	glutathionylspermidine amidase activity
BWP24_RS11380	COG3766	membrane
BWP24_RS11395	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BWP24_RS11400	COG2885	chlorophyll binding
BWP24_RS11405	COG0823	Involved in the tonB-independent uptake of proteins
BWP24_RS11420	COG0811	peptide transport
BWP24_RS11425	COG0824	Thioesterase
BWP24_RS11435	COG4890	Cyd operon protein YbgT
BWP24_RS11440	COG1294	oxidase, subunit
BWP24_RS11445	COG1271	oxidase subunit
BWP24_RS11455	COG0632	four-way junction helicase activity
BWP24_RS11460	COG0840	transmembrane signaling receptor activity
BWP24_RS11475	COG1801	Protein of unknown function DUF72
BWP24_RS11490	COG0189	ligase activity
BWP24_RS11490	COG4067	protein conserved in archaea
BWP24_RS11510	COG0318	PFAM AMP-dependent synthetase and ligase
BWP24_RS11525	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BWP24_RS11530	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BWP24_RS11540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BWP24_RS11545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BWP24_RS11550	COG0745	RESPONSE REGULATOR receiver
BWP24_RS11565	COG3070	regulator of competence-specific genes
BWP24_RS11585	COG0297	glycogen (starch) synthase activity
BWP24_RS11590	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BWP24_RS11595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BWP24_RS11625	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BWP24_RS11630	COG0542	response to heat
BWP24_RS11640	COG1278	Cold shock
BWP24_RS11650	COG1187	pseudouridine synthase activity
BWP24_RS11655	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BWP24_RS11665	COG1199	ATP-dependent helicase activity
BWP24_RS11670	COG0730	response to heat
BWP24_RS11675	COG3923	Primosomal replication protein n
BWP24_RS11685	COG0708	Exodeoxyribonuclease III
BWP24_RS11720	COG1882	Formate acetyltransferase
BWP24_RS11730	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BWP24_RS11745	COG2766	serine protein kinase
BWP24_RS11750	COG2718	Belongs to the UPF0229 family
BWP24_RS11755	COG2719	SpoVR family
BWP24_RS11775	COG1132	(ABC) transporter
BWP24_RS11780	COG2333	competence protein COMEC
BWP24_RS11780	COG0658	competence protein
BWP24_RS11790	COG4591	ABC-type transport system involved in lipoprotein release permease component
BWP24_RS11795	COG1136	(ABC) transporter
BWP24_RS11800	COG4591	ABC-type transport system involved in lipoprotein release permease component
BWP24_RS11810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BWP24_RS11825	COG1252	NADH dehydrogenase
BWP24_RS11855	COG0537	adenosine 5'-monophosphoramidase activity
BWP24_RS11875	COG2217	Heavy metal translocating P-type atpase
BWP24_RS11885	COG0516	GMP reductase activity
BWP24_RS11885	COG0517	IMP dehydrogenase activity
BWP24_RS11890	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BWP24_RS11895	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BWP24_RS11900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BWP24_RS11910	COG3706	GGDEF domain
BWP24_RS11925	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BWP24_RS11930	COG1946	Acyl-CoA thioesterase
BWP24_RS11935	COG1522	sequence-specific DNA binding
BWP24_RS11960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWP24_RS12015	COG2855	membrane
BWP24_RS12020	COG0583	DNA-binding transcription factor activity
BWP24_RS12025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWP24_RS12025	COG2190	(PTS) system
BWP24_RS12025	COG1263	PTS System
BWP24_RS12040	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BWP24_RS12045	COG0596	Alpha beta hydrolase
BWP24_RS12055	COG1169	isochorismate synthase
BWP24_RS12060	COG0436	Aminotransferase
BWP24_RS12065	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BWP24_RS12085	COG1555	photosystem II stabilization
BWP24_RS12090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BWP24_RS12095	COG0776	regulation of translation
BWP24_RS12100	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BWP24_RS12135	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BWP24_RS12140	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BWP24_RS12145	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BWP24_RS12160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BWP24_RS12165	COG0569	domain protein
BWP24_RS12170	COG0513	Belongs to the DEAD box helicase family
BWP24_RS12175	COG1253	flavin adenine dinucleotide binding
BWP24_RS12180	COG4771	TonB-dependent receptor
BWP24_RS12185	COG2977	Belongs to the P-Pant transferase superfamily
BWP24_RS12195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BWP24_RS12195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BWP24_RS12200	COG3433	isochorismatase activity
BWP24_RS12200	COG1535	isochorismatase
BWP24_RS12205	COG1021	2,3-dihydroxybenzoate-AMP ligase
BWP24_RS12210	COG1169	isochorismate synthase
BWP24_RS12220	COG1028	Short-chain dehydrogenase reductase Sdr
BWP24_RS12255	COG1104	cysteine desulfurase activity
BWP24_RS12275	COG0556	nucleotide-excision repair
BWP24_RS12315	COG2852	Protein conserved in bacteria
BWP24_RS12320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWP24_RS12330	COG2951	lytic endotransglycosylase activity
BWP24_RS12345	COG2894	cell division
BWP24_RS12350	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BWP24_RS12355	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BWP24_RS12360	COG0318	PFAM AMP-dependent synthetase and ligase
BWP24_RS12365	COG2267	carboxylic ester hydrolase activity
BWP24_RS12370	COG3065	identical protein binding
BWP24_RS12380	COG1214	PFAM Peptidase M22, glycoprotease
BWP24_RS12385	COG1199	ATP-dependent helicase activity
BWP24_RS12395	COG0788	formyltetrahydrofolate deformylase activity
BWP24_RS12410	COG3102	Protein conserved in bacteria
BWP24_RS12440	COG1918	ferrous iron import across plasma membrane
BWP24_RS12445	COG4977	sequence-specific DNA binding
BWP24_RS12450	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BWP24_RS12455	COG1121	(ABC) transporter
BWP24_RS12460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BWP24_RS12475	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWP24_RS12480	COG0567	Dehydrogenase, E1 component
BWP24_RS12490	COG1053	succinate dehydrogenase
BWP24_RS12495	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BWP24_RS12510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BWP24_RS12525	COG0033	Phosphoglucomutase
BWP24_RS12530	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BWP24_RS12535	COG0596	Alpha beta hydrolase
BWP24_RS12555	COG0735	belongs to the Fur family
BWP24_RS12560	COG2165	general secretion pathway protein
BWP24_RS12570	COG1263	PTS System
BWP24_RS12570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWP24_RS12570	COG2190	(PTS) system
BWP24_RS12575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BWP24_RS12580	COG1846	Transcriptional regulator
BWP24_RS12580	COG1940	carbohydrate kinase activity
BWP24_RS12585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BWP24_RS12585	COG4651	solute:proton antiporter activity
BWP24_RS12590	COG0367	asparagine synthase
BWP24_RS12600	COG3104	oligopeptide transport
BWP24_RS12605	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BWP24_RS12620	COG3710	Transcriptional regulator
BWP24_RS12640	COG0622	Phosphoesterase
BWP24_RS12670	COG1090	epimerase
BWP24_RS12675	COG0300	oxidoreductase activity
BWP24_RS12685	COG3118	belongs to the thioredoxin family
BWP24_RS12690	COG0457	Tetratricopeptide repeat
BWP24_RS12690	COG3118	belongs to the thioredoxin family
BWP24_RS12695	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BWP24_RS12700	COG1215	transferase activity, transferring glycosyl groups
BWP24_RS12705	COG1215	transferase activity, transferring glycosyl groups
BWP24_RS12710	COG1192	Involved in chromosome partitioning
BWP24_RS12725	COG2194	sulfuric ester hydrolase activity
BWP24_RS12730	COG0330	HflC and HflK could
BWP24_RS12765	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BWP24_RS12770	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWP24_RS12780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWP24_RS12785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BWP24_RS12790	COG2190	(PTS) system
BWP24_RS12795	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWP24_RS12800	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWP24_RS12810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWP24_RS12825	COG3951	Flagellar rod assembly protein muramidase FlgJ
BWP24_RS12825	COG1705	Flagellar rod assembly protein muramidase FlgJ
BWP24_RS12830	COG1706	bacterial-type flagellum-dependent cell motility
BWP24_RS12835	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BWP24_RS12845	COG4787	bacterial-type flagellum-dependent cell motility
BWP24_RS12850	COG1749	Flagellar hook protein flgE
BWP24_RS12860	COG1558	bacterial-type flagellum-dependent cell motility
BWP24_RS12865	COG1815	bacterial-type flagellum-dependent cell motility
BWP24_RS12870	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BWP24_RS12875	COG0784	Response regulator, receiver
BWP24_RS12875	COG0835	chemotaxis
BWP24_RS12935	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BWP24_RS12945	COG2608	mercury ion transmembrane transporter activity
BWP24_RS12945	COG2217	Heavy metal translocating P-type atpase
BWP24_RS12985	COG2840	Smr protein MutS2
BWP24_RS12990	COG1187	pseudouridine synthase activity
BWP24_RS12995	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BWP24_RS13000	COG0737	Belongs to the 5'-nucleotidase family
BWP24_RS13010	COG2912	Transglutaminase-like superfamily
BWP24_RS13015	COG3094	Invasion gene expression up-regulator, SirB
BWP24_RS13020	COG2890	protein-(glutamine-N5) methyltransferase activity
BWP24_RS13045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BWP24_RS13170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BWP24_RS13180	COG1702	phosphate starvation-inducible protein PhoH
BWP24_RS13190	COG4535	Mg2 and Co2 transporter CorC
BWP24_RS13195	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BWP24_RS13200	COG2888	peptidyl-tyrosine sulfation
BWP24_RS13210	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BWP24_RS13215	COG1466	dna polymerase III delta subunit
BWP24_RS13220	COG0799	negative regulation of ribosome biogenesis
BWP24_RS13230	COG0768	penicillin binding
BWP24_RS13235	COG0772	Belongs to the SEDS family
BWP24_RS13240	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BWP24_RS13245	COG1686	Belongs to the peptidase S11 family
BWP24_RS13265	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BWP24_RS13270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWP24_RS13285	COG0366	Alpha amylase catalytic
BWP24_RS13290	COG1263	PTS System
BWP24_RS13290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWP24_RS13300	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BWP24_RS13305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BWP24_RS13310	COG2011	ABC-type metal ion transport system permease component
BWP24_RS13315	COG1464	Belongs to the NlpA lipoprotein family
BWP24_RS13325	COG0737	Belongs to the 5'-nucleotidase family
BWP24_RS13330	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BWP24_RS13355	COG1611	Belongs to the LOG family
BWP24_RS13375	COG2363	Small membrane protein
BWP24_RS13385	COG0583	DNA-binding transcription factor activity
BWP24_RS13400	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BWP24_RS13410	COG0142	geranyltranstransferase activity
BWP24_RS13420	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BWP24_RS13425	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BWP24_RS13450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BWP24_RS13450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BWP24_RS13455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BWP24_RS13460	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BWP24_RS13475	COG1073	alpha beta
BWP24_RS13485	COG2252	PERMEase
BWP24_RS13490	COG2195	Cleaves the N-terminal amino acid of tripeptides
BWP24_RS13515	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BWP24_RS13515	COG0047	phosphoribosylformylglycinamidine synthase activity
BWP24_RS13525	COG0590	tRNA wobble adenosine to inosine editing
BWP24_RS13535	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BWP24_RS13555	COG4969	Belongs to the N-Me-Phe pilin family
BWP24_RS13575	COG1301	dicarboxylic acid transport
BWP24_RS13590	COG0497	DNA recombination
BWP24_RS13595	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BWP24_RS13600	COG2914	Belongs to the UPF0125 (RnfH) family
BWP24_RS13605	COG2867	negative regulation of translational initiation
BWP24_RS13620	COG0583	DNA-binding transcription factor activity
BWP24_RS13625	COG1289	transmembrane transporter activity
BWP24_RS13645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BWP24_RS13650	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BWP24_RS13655	COG0668	transmembrane transport
BWP24_RS13675	COG0583	DNA-binding transcription factor activity
BWP24_RS13685	COG1115	amino acid carrier protein
BWP24_RS13690	COG1584	GPR1 FUN34 yaaH family protein
BWP24_RS13700	COG1757	Na H antiporter
BWP24_RS13710	COG0516	GMP reductase activity
BWP24_RS13710	COG0517	IMP dehydrogenase activity
BWP24_RS13725	COG2203	Gaf domain
BWP24_RS13725	COG2199	diguanylate cyclase activity
BWP24_RS13740	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BWP24_RS13745	COG2976	Protein conserved in bacteria
BWP24_RS13760	COG1426	Protein conserved in bacteria
BWP24_RS13780	COG2975	iron-sulfur cluster assembly
BWP24_RS13785	COG0633	Ferredoxin
BWP24_RS13800	COG0316	Belongs to the HesB IscA family
BWP24_RS13805	COG0822	iron-sulfur transferase activity
BWP24_RS13820	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BWP24_RS13825	COG0483	inositol monophosphate 1-phosphatase activity
BWP24_RS13830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWP24_RS13835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWP24_RS13840	COG1862	Preprotein translocase
BWP24_RS13865	COG0517	IMP dehydrogenase activity
BWP24_RS13875	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BWP24_RS13880	COG0583	DNA-binding transcription factor activity
BWP24_RS13885	COG0450	alkyl hydroperoxide reductase
BWP24_RS13915	COG0704	Plays a role in the regulation of phosphate uptake
BWP24_RS13920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BWP24_RS13925	COG0581	inorganic phosphate transmembrane transporter activity
BWP24_RS13930	COG0573	inorganic phosphate transmembrane transporter activity
BWP24_RS13935	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BWP24_RS13940	COG0248	Ppx GppA phosphatase
BWP24_RS13950	COG5002	protein histidine kinase activity
BWP24_RS13955	COG0745	RESPONSE REGULATOR receiver
BWP24_RS13970	COG0826	peptidase U32
BWP24_RS13975	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BWP24_RS14035	COG0542	response to heat
BWP24_RS14040	COG1496	oxidoreductase activity
BWP24_RS14045	COG0564	pseudouridine synthase activity
BWP24_RS14050	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BWP24_RS14055	COG0741	lytic transglycosylase activity
BWP24_RS14060	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BWP24_RS14065	COG0077	Prephenate dehydratase
BWP24_RS14065	COG1605	Chorismate mutase
BWP24_RS14070	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BWP24_RS14085	COG0488	(ABC) transporter
BWP24_RS14095	COG0739	heme binding
BWP24_RS14100	COG0287	Prephenate dehydrogenase
BWP24_RS14100	COG1605	Chorismate mutase
BWP24_RS14105	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BWP24_RS14115	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BWP24_RS14135	COG1966	Carbon starvation protein
BWP24_RS14140	COG3275	phosphorelay sensor kinase activity
BWP24_RS14145	COG3279	Response regulator of the LytR AlgR family
BWP24_RS14150	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BWP24_RS14155	COG1047	Peptidyl-prolyl cis-trans
BWP24_RS14170	COG0196	riboflavin kinase activity
BWP24_RS14175	COG0728	peptidoglycan biosynthetic process
BWP24_RS14180	COG0268	Binds directly to 16S ribosomal RNA
BWP24_RS14185	COG0640	Transcriptional regulator
BWP24_RS14190	COG0583	DNA-binding transcription factor activity
BWP24_RS14195	COG1283	sodium-dependent phosphate transmembrane transporter activity
BWP24_RS14210	COG0730	response to heat
BWP24_RS14235	COG0667	Aldo Keto reductase
BWP24_RS14260	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BWP24_RS14265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BWP24_RS14270	COG4974	Belongs to the 'phage' integrase family
BWP24_RS14275	COG0716	FMN binding
BWP24_RS14290	COG0513	Belongs to the DEAD box helicase family
BWP24_RS14300	COG3022	response to hydroperoxide
BWP24_RS14305	COG1115	amino acid carrier protein
BWP24_RS14340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BWP24_RS14345	COG0083	homoserine kinase activity
BWP24_RS14360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BWP24_RS14370	COG0745	RESPONSE REGULATOR receiver
BWP24_RS14380	COG0784	Response regulator, receiver
BWP24_RS14380	COG5002	protein histidine kinase activity
BWP24_RS14380	COG2198	Histidine kinase
BWP24_RS14390	COG2203	Gaf domain
BWP24_RS14390	COG5001	Diguanylate cyclase
BWP24_RS14390	COG3706	GGDEF domain
BWP24_RS14390	COG4251	negative regulation of phosphorylation
BWP24_RS14395	COG1242	4 iron, 4 sulfur cluster binding
BWP24_RS14400	COG0070	glutamate synthase
BWP24_RS14400	COG0069	glutamate synthase activity
BWP24_RS14400	COG0067	glutamate synthase
BWP24_RS14410	COG0070	glutamate synthase
BWP24_RS14410	COG0067	glutamate synthase
BWP24_RS14410	COG0069	glutamate synthase activity
BWP24_RS14415	COG0493	'glutamate synthase
BWP24_RS14440	COG2860	membrane
BWP24_RS14445	COG0583	DNA-binding transcription factor activity
BWP24_RS14450	COG0730	response to heat
BWP24_RS14465	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BWP24_RS14470	COG0505	Belongs to the CarA family
BWP24_RS14480	COG0494	nUDIX hydrolase
BWP24_RS14500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BWP24_RS14505	COG0849	cell division
BWP24_RS14510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BWP24_RS14525	COG0772	Belongs to the SEDS family
BWP24_RS14540	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BWP24_RS14545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BWP24_RS14550	COG0768	penicillin binding
BWP24_RS14555	COG3116	cell division
BWP24_RS14570	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BWP24_RS14585	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BWP24_RS14590	COG2823	Periplasmic or secreted lipoprotein
BWP24_RS14595	COG2969	positive regulation of protein catabolic process
BWP24_RS14600	COG0625	glutathione transferase activity
BWP24_RS14605	COG2857	Cytochrome c1
BWP24_RS14610	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BWP24_RS14615	COG0723	plastoquinol--plastocyanin reductase activity
BWP24_RS14630	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BWP24_RS14635	COG3105	Protein conserved in bacteria
BWP24_RS14640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWP24_RS14645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWP24_RS14650	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BWP24_RS14660	COG3150	esterase
BWP24_RS14670	COG3151	Protein conserved in bacteria
BWP24_RS14675	COG0494	nUDIX hydrolase
BWP24_RS14680	COG1538	Outer membrane efflux protein
BWP24_RS14690	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BWP24_RS14700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BWP24_RS14705	COG3025	triphosphatase activity
BWP24_RS14710	COG1392	Phosphate transport regulator
BWP24_RS14715	COG0306	phosphate transporter
BWP24_RS14720	COG4991	sh3 domain protein
BWP24_RS14725	COG0405	Gamma-glutamyltransferase
BWP24_RS14735	COG3409	Peptidoglycan-binding domain 1 protein
BWP24_RS14735	COG3267	Type II secretory pathway component ExeA
BWP24_RS14750	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BWP24_RS14755	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BWP24_RS14765	COG0596	Alpha beta hydrolase
BWP24_RS14770	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BWP24_RS14775	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BWP24_RS14780	COG1610	YqeY-like protein
BWP24_RS14785	COG0358	DNA primase activity
BWP24_RS14825	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWP24_RS14825	COG2213	PTS system mannitol-specific
BWP24_RS14835	COG3722	fumarate hydratase activity
BWP24_RS14840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BWP24_RS14845	COG5002	protein histidine kinase activity
BWP24_RS14865	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BWP24_RS14870	COG1349	DNA-binding transcription factor activity
BWP24_RS14875	COG0469	pyruvate kinase activity
BWP24_RS14885	COG3706	GGDEF domain
BWP24_RS14890	COG0440	acetolactate synthase activity
BWP24_RS14895	COG0028	Belongs to the TPP enzyme family
BWP24_RS14900	COG1022	Amp-dependent synthetase and ligase
BWP24_RS14905	COG0583	DNA-binding transcription factor activity
BWP24_RS14930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BWP24_RS14935	COG0473	3-isopropylmalate dehydrogenase activity
BWP24_RS14955	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BWP24_RS14960	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BWP24_RS14965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BWP24_RS14970	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BWP24_RS14995	COG3610	response to peptide
BWP24_RS15000	COG2966	Psort location CytoplasmicMembrane, score
BWP24_RS15015	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BWP24_RS15020	COG0142	geranyltranstransferase activity
BWP24_RS15040	COG2358	TRAP transporter, solute receptor (TAXI family
BWP24_RS15055	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BWP24_RS15060	COG1178	ABC-type Fe3 transport system permease component
BWP24_RS15065	COG4143	(ABC) transporter
BWP24_RS15070	COG0163	prenyltransferase activity
BWP24_RS15075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BWP24_RS15085	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BWP24_RS15100	COG2105	PFAM AIG2 family protein
BWP24_RS15110	COG0729	surface antigen
BWP24_RS15115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWP24_RS15125	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BWP24_RS15140	COG1136	(ABC) transporter
BWP24_RS15160	COG0529	Catalyzes the synthesis of activated sulfate
BWP24_RS15165	COG0471	metal ion transport
BWP24_RS15165	COG3273	potassium ion transport
BWP24_RS15180	COG1648	precorrin-2 dehydrogenase activity
BWP24_RS15180	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BWP24_RS15185	COG0737	Belongs to the 5'-nucleotidase family
BWP24_RS15195	COG0513	Belongs to the DEAD box helicase family
BWP24_RS15200	COG2153	protein acetylation
BWP24_RS15215	COG0545	Peptidyl-prolyl cis-trans isomerase
BWP24_RS15225	COG0203	ribosomal protein L17
BWP24_RS15230	COG0202	RNA polymerase activity
BWP24_RS15240	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BWP24_RS15245	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BWP24_RS15250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BWP24_RS15255	COG0201	protein transport
BWP24_RS15265	COG1841	ribosomal large subunit assembly
BWP24_RS15350	COG0088	Forms part of the polypeptide exit tunnel
BWP24_RS15370	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BWP24_RS15375	COG1609	Transcriptional regulator
BWP24_RS15395	COG1575	Belongs to the MenA family. Type 1 subfamily
BWP24_RS15400	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BWP24_RS15410	COG1494	fructose-1,6-bisphosphatase
BWP24_RS15435	COG0149	triose-phosphate isomerase activity
BWP24_RS15470	COG1216	Glycosyl transferase, family 2
BWP24_RS15495	COG1215	transferase activity, transferring glycosyl groups
BWP24_RS15500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BWP24_RS15505	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BWP24_RS15510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BWP24_RS15515	COG1215	transferase activity, transferring glycosyl groups
BWP24_RS15540	COG2244	polysaccharide biosynthetic process
BWP24_RS15545	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BWP24_RS15595	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BWP24_RS15605	COG1560	Kdo2-lipid A biosynthetic process
BWP24_RS15615	COG0438	transferase activity, transferring glycosyl groups
BWP24_RS15620	COG1519	Transferase
BWP24_RS15625	COG1216	Glycosyl transferase, family 2
BWP24_RS15625	COG1442	glycosyl transferase family 8
BWP24_RS15630	COG5039	Polysaccharide pyruvyl transferase
BWP24_RS15635	COG3642	lipopolysaccharide core region biosynthetic process
BWP24_RS15640	COG0859	PFAM glycosyl transferase family 9
BWP24_RS15650	COG0438	transferase activity, transferring glycosyl groups
BWP24_RS15665	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BWP24_RS15695	COG0840	transmembrane signaling receptor activity
BWP24_RS15700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BWP24_RS15710	COG1560	Kdo2-lipid A biosynthetic process
BWP24_RS15715	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BWP24_RS15720	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BWP24_RS15725	COG1561	YicC-like family, N-terminal region
BWP24_RS15745	COG4608	Belongs to the ABC transporter superfamily
BWP24_RS15750	COG0444	Belongs to the ABC transporter superfamily
BWP24_RS15755	COG0747	negative chemotaxis
BWP24_RS15760	COG4239	(ABC) transporter, permease
BWP24_RS15765	COG4174	ABC transporter (Permease)
BWP24_RS15770	COG4206	TonB-dependent receptor
BWP24_RS15785	COG0811	peptide transport
BWP24_RS15790	COG0848	biopolymer transport protein
BWP24_RS15805	COG0194	GDP metabolic process
BWP24_RS15810	COG1758	RNA polymerase activity
BWP24_RS15815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BWP24_RS15820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BWP24_RS15825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BWP24_RS15835	COG2233	PERMEase
BWP24_RS15850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BWP24_RS15860	COG2183	response to ionizing radiation
BWP24_RS15875	COG1040	competence protein
BWP24_RS15885	COG0494	nUDIX hydrolase
BWP24_RS15890	COG1218	3'(2'),5'-bisphosphate nucleotidase
BWP24_RS15900	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BWP24_RS15905	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BWP24_RS15910	COG3156	type II secretion system protein K
BWP24_RS15915	COG4795	General secretion pathway protein
BWP24_RS15920	COG2165	general secretion pathway protein
BWP24_RS15925	COG2165	general secretion pathway protein
BWP24_RS15930	COG2165	general secretion pathway protein
BWP24_RS15935	COG1459	type II secretion system
BWP24_RS15940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BWP24_RS15950	COG3031	protein transport across the cell outer membrane
BWP24_RS15955	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BWP24_RS15975	COG0456	acetyltransferase
BWP24_RS15980	COG1490	D-aminoacyl-tRNA deacylase activity
BWP24_RS16000	COG1217	gtp-binding protein TYPA
BWP24_RS16010	COG0174	glutamine synthetase
BWP24_RS16020	COG3852	Histidine kinase
BWP24_RS16025	COG2204	response regulator
BWP24_RS16030	COG3300	MHYT domain
BWP24_RS16030	COG5001	Diguanylate cyclase
BWP24_RS16035	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BWP24_RS16070	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BWP24_RS16075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BWP24_RS16075	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BWP24_RS16095	COG0084	hydrolase, TatD family'
BWP24_RS16100	COG0805	protein transport
BWP24_RS16105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BWP24_RS16120	COG3165	ubiquinone biosynthetic process from chorismate
BWP24_RS16130	COG1322	Protein conserved in bacteria
BWP24_RS16145	COG1910	domain protein
BWP24_RS16165	COG2081	HI0933 family
BWP24_RS16175	COG1528	Iron-storage protein
BWP24_RS16180	COG0589	response to stress
BWP24_RS16200	COG5001	Diguanylate cyclase
BWP24_RS16200	COG5002	protein histidine kinase activity
BWP24_RS16205	COG1522	sequence-specific DNA binding
BWP24_RS16220	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BWP24_RS16230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWP24_RS16275	COG3550	peptidyl-serine autophosphorylation
BWP24_RS16320	COG0800	Aldolase
BWP24_RS16325	COG2610	gluconate transmembrane transporter activity
BWP24_RS16330	COG3265	gluconokinase activity
BWP24_RS16335	COG0129	dihydroxy-acid dehydratase activity
BWP24_RS16345	COG2076	Multidrug Resistance protein
BWP24_RS16350	COG0583	DNA-binding transcription factor activity
BWP24_RS16355	COG1609	Transcriptional regulator
BWP24_RS16360	COG0515	serine threonine protein kinase
BWP24_RS16390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWP24_RS16395	COG0601	transmembrane transport
BWP24_RS16400	COG4166	transmembrane transport
BWP24_RS16405	COG4172	Belongs to the ABC transporter superfamily
BWP24_RS16455	COG1309	transcriptional regulator
BWP24_RS16460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWP24_RS16465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWP24_RS16470	COG2960	long-chain fatty acid transporting porin activity
BWP24_RS16480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BWP24_RS16485	COG0583	DNA-binding transcription factor activity
BWP24_RS17110	COG0151	Belongs to the GarS family
BWP24_RS17490	COG0840	transmembrane signaling receptor activity
BWP24_RS17865	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BWP24_RS18250	COG1077	Cell shape determining protein MreB Mrl
BWP24_RS18370	COG0312	modulator of DNA gyrase
BWP24_RS19210	COG1049	propionate catabolic process, 2-methylcitrate cycle
BWP24_RS19485	COG0534	Mate efflux family protein
BWP24_RS19540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWP24_RS19600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BWP24_RS19780	COG0768	penicillin binding
BWP24_RS20190	COG1960	acyl-CoA dehydrogenase activity
BWP24_RS20255	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BWP24_RS20305	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWP24_RS20675	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BWP24_RS20820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BWP24_RS21205	COG2885	chlorophyll binding
BWP24_RS21320	COG0556	nucleotide-excision repair
BWP24_RS21530	COG1530	ribonuclease E activity
BWP24_RS21995	COG0840	transmembrane signaling receptor activity
BWP24_RS22365	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BWP24_RS23015	COG1132	(ABC) transporter
BWP24_RS23240	COG1643	Atp-dependent helicase
BWP24_RS23760	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BWP24_RS24080	COG4597	amino acid ABC transporter
BWP24_RS24275	COG3278	Belongs to the heme-copper respiratory oxidase family
BWP24_RS24295	COG2217	Heavy metal translocating P-type atpase
BWP24_RS24475	COG0840	transmembrane signaling receptor activity
BWP24_RS24840	COG1404	Belongs to the peptidase S8 family
BWP24_RS25980	COG1960	acyl-CoA dehydrogenase activity
BWP24_RS26065	COG1187	pseudouridine synthase activity
BWP24_RS26340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWP24_RS26635	COG3071	HemY protein
BWP24_RS26755	COG2095	MarC family integral membrane protein
BWP24_RS26775	COG2884	Cell division ATP-binding protein ftsE
BWP24_RS27045	COG0138	bifunctional purine biosynthesis protein purh
BWP24_RS27255	COG0210	DNA helicase
BWP24_RS27335	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BWP24_RS27405	COG0019	diaminopimelate decarboxylase activity
BWP24_RS27445	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BWP24_RS27555	COG2937	Belongs to the GPAT DAPAT family
BWP24_RS28015	COG0210	DNA helicase
BWP24_RS28365	COG0552	protein localization to endoplasmic reticulum
BWP24_RS28370	COG0552	protein localization to endoplasmic reticulum
BWP24_RS28690	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BWP24_RS28825	COG3072	Adenylate cyclase
BWP24_RS28845	COG3072	Adenylate cyclase
BWP24_RS28900	COG2199	diguanylate cyclase activity
BWP24_RS28900	COG2200	EAL domain
BWP24_RS28900	COG3287	FIST C domain
BWP24_RS28940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BWP24_RS29070	COG0534	Mate efflux family protein