locus-tag	class	description
VAB027_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VAB027_RS00010	COG0592	DNA-directed DNA polymerase activity
VAB027_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VAB027_RS00020	COG0187	DNA topoisomerase II activity
VAB027_RS00035	COG0071	Belongs to the small heat shock protein (HSP20) family
VAB027_RS00040	COG3977	Valine--pyruvate aminotransferase
VAB027_RS00045	COG0751	glycine-tRNA ligase activity
VAB027_RS00050	COG0752	glycyl-tRNA synthetase alpha subunit
VAB027_RS00055	COG2119	membrane
VAB027_RS00065	COG0425	Belongs to the sulfur carrier protein TusA family
VAB027_RS00075	COG0604	alcohol dehydrogenase
VAB027_RS00085	COG0129	dihydroxy-acid dehydratase activity
VAB027_RS00090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VAB027_RS00105	COG0606	chelatase, subunit chli
VAB027_RS00110	COG0204	Acyl-transferase
VAB027_RS00115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VAB027_RS00120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VAB027_RS00130	COG3084	Protein conserved in bacteria
VAB027_RS00140	COG4326	sporulation control protein
VAB027_RS00145	COG1272	protein, Hemolysin III
VAB027_RS00155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VAB027_RS00160	COG0569	domain protein
VAB027_RS00165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VAB027_RS00165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VAB027_RS00170	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VAB027_RS00175	COG0242	peptide deformylase activity
VAB027_RS00180	COG1652	LysM domain
VAB027_RS00185	COG0758	DNA mediated transformation
VAB027_RS00190	COG2922	Belongs to the Smg family
VAB027_RS00195	COG0551	DNA topoisomerase type I activity
VAB027_RS00200	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VAB027_RS00205	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VAB027_RS00210	COG0009	L-threonylcarbamoyladenylate synthase
VAB027_RS00215	COG0408	coproporphyrinogen oxidase activity
VAB027_RS00220	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VAB027_RS00230	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VAB027_RS00265	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VAB027_RS00270	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VAB027_RS00280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VAB027_RS00285	COG2104	thiamine diphosphate biosynthetic process
VAB027_RS00290	COG2022	thiamine diphosphate biosynthetic process
VAB027_RS00295	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VAB027_RS00300	COG0006	proline dipeptidase activity
VAB027_RS00300	COG0006	proline dipeptidase activity
VAB027_RS00320	COG1522	sequence-specific DNA binding
VAB027_RS00325	COG5002	protein histidine kinase activity
VAB027_RS00325	COG5001	Diguanylate cyclase
VAB027_RS00345	COG0589	response to stress
VAB027_RS00355	COG1528	Iron-storage protein
VAB027_RS00365	COG2081	HI0933 family
VAB027_RS00375	COG1322	Protein conserved in bacteria
VAB027_RS00380	COG2226	methyltransferase
VAB027_RS00395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VAB027_RS00400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VAB027_RS00405	COG0805	protein transport
VAB027_RS00410	COG1858	cytochrome C peroxidase
VAB027_RS00415	COG0534	Mate efflux family protein
VAB027_RS00425	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VAB027_RS00430	COG2937	Belongs to the GPAT DAPAT family
VAB027_RS00435	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VAB027_RS00440	COG3161	chorismate lyase activity
VAB027_RS00450	COG1580	Controls the rotational direction of flagella during chemotaxis
VAB027_RS00455	COG0840	transmembrane signaling receptor activity
VAB027_RS00465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VAB027_RS00475	COG0084	hydrolase, TatD family'
VAB027_RS00490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VAB027_RS00490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VAB027_RS00510	COG3078	GTPase activator activity
VAB027_RS00525	COG3071	HemY protein
VAB027_RS00530	COG2959	enzyme of heme biosynthesis
VAB027_RS00535	COG1587	Uroporphyrinogen-III synthase
VAB027_RS00540	COG0181	hydroxymethylbilane synthase activity
VAB027_RS00555	COG1965	Belongs to the frataxin family
VAB027_RS00565	COG0019	diaminopimelate decarboxylase activity
VAB027_RS00570	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VAB027_RS00580	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VAB027_RS00585	COG1011	Hydrolase
VAB027_RS00590	COG2199	diguanylate cyclase activity
VAB027_RS00590	COG2200	EAL domain
VAB027_RS00590	COG3287	FIST C domain
VAB027_RS00595	COG3148	PFAM DTW domain containing protein
VAB027_RS00610	COG0561	phosphatase activity
VAB027_RS00615	COG2267	carboxylic ester hydrolase activity
VAB027_RS00620	COG1280	lysine exporter protein (LysE YggA)
VAB027_RS00625	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VAB027_RS00630	COG0783	Belongs to the Dps family
VAB027_RS00665	COG0742	ribosomal rna small subunit methyltransferase
VAB027_RS00670	COG0552	protein localization to endoplasmic reticulum
VAB027_RS00675	COG2884	Cell division ATP-binding protein ftsE
VAB027_RS00680	COG2177	Part of the ABC transporter FtsEX involved in
VAB027_RS00685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VAB027_RS00690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VAB027_RS00705	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VAB027_RS00720	COG1404	Belongs to the peptidase S8 family
VAB027_RS00725	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VAB027_RS00760	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VAB027_RS00765	COG3300	MHYT domain
VAB027_RS00765	COG5001	Diguanylate cyclase
VAB027_RS00775	COG3852	Histidine kinase
VAB027_RS00785	COG0174	glutamine synthetase
VAB027_RS00795	COG1217	gtp-binding protein TYPA
VAB027_RS00805	COG1295	ribonuclease BN
VAB027_RS00810	COG1490	D-aminoacyl-tRNA deacylase activity
VAB027_RS00815	COG0456	acetyltransferase
VAB027_RS00825	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VAB027_RS00830	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VAB027_RS00835	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VAB027_RS00840	COG3031	protein transport across the cell outer membrane
VAB027_RS00850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VAB027_RS00855	COG1459	type II secretion system
VAB027_RS00860	COG2165	general secretion pathway protein
VAB027_RS00865	COG2165	general secretion pathway protein
VAB027_RS00870	COG2165	general secretion pathway protein
VAB027_RS00875	COG4795	General secretion pathway protein
VAB027_RS00880	COG3156	type II secretion system protein K
VAB027_RS00885	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VAB027_RS00890	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VAB027_RS00900	COG1218	3'(2'),5'-bisphosphate nucleotidase
VAB027_RS00905	COG0494	nUDIX hydrolase
VAB027_RS00915	COG1040	competence protein
VAB027_RS00920	COG0596	Alpha beta hydrolase
VAB027_RS00930	COG2183	response to ionizing radiation
VAB027_RS00935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VAB027_RS00940	COG2199	diguanylate cyclase activity
VAB027_RS00955	COG2233	PERMEase
VAB027_RS00960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VAB027_RS00965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VAB027_RS00970	COG1758	RNA polymerase activity
VAB027_RS00975	COG0194	GDP metabolic process
VAB027_RS00980	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VAB027_RS01005	COG4232	protein-disulfide reductase activity
VAB027_RS01025	COG1027	Aspartate ammonia-lyase
VAB027_RS01030	COG3706	GGDEF domain
VAB027_RS01035	COG3030	protein affecting phage T7 exclusion by the F plasmid
VAB027_RS01040	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VAB027_RS01050	COG2205	protein histidine kinase activity
VAB027_RS01055	COG0745	RESPONSE REGULATOR receiver
VAB027_RS01065	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VAB027_RS01070	COG0205	6-phosphofructokinase activity
VAB027_RS01080	COG3074	FtsZ-dependent cytokinesis
VAB027_RS01085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VAB027_RS01090	COG0527	aspartate kinase activity
VAB027_RS01090	COG0460	homoserine dehydrogenase
VAB027_RS01095	COG0626	cystathionine gamma-synthase activity
VAB027_RS01100	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VAB027_RS01105	COG0281	malic enzyme
VAB027_RS01110	COG0254	rRNA binding
VAB027_RS01115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VAB027_RS01120	COG1609	Transcriptional regulator
VAB027_RS01125	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VAB027_RS01130	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VAB027_RS01135	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VAB027_RS01140	COG1575	Belongs to the MenA family. Type 1 subfamily
VAB027_RS01145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VAB027_RS01150	COG0534	Mate efflux family protein
VAB027_RS01155	COG0149	triose-phosphate isomerase activity
VAB027_RS01180	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VAB027_RS01185	COG0459	protein refolding
VAB027_RS01195	COG1509	lysine 2,3-aminomutase activity
VAB027_RS01200	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VAB027_RS01210	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VAB027_RS01215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VAB027_RS01220	COG1053	succinate dehydrogenase
VAB027_RS01225	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VAB027_RS01230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VAB027_RS01235	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VAB027_RS01240	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VAB027_RS01245	COG1045	serine acetyltransferase
VAB027_RS01255	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VAB027_RS01260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VAB027_RS01265	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VAB027_RS01270	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VAB027_RS01275	COG0137	argininosuccinate synthase activity
VAB027_RS01280	COG0165	Argininosuccinate lyase
VAB027_RS01290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VAB027_RS01295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VAB027_RS01295	COG0678	peroxiredoxin activity
VAB027_RS01305	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VAB027_RS01335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VAB027_RS01340	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VAB027_RS01350	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VAB027_RS01355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VAB027_RS01360	COG0546	phosphoglycolate phosphatase activity
VAB027_RS01365	COG0180	Tryptophanyl-tRNA synthetase
VAB027_RS01380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VAB027_RS01390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VAB027_RS01410	COG3385	transposase activity
VAB027_RS01520	COG0557	exoribonuclease II activity
VAB027_RS01525	COG1278	Cold shock
VAB027_RS01585	COG0583	DNA-binding transcription factor activity
VAB027_RS01590	COG3048	D-serine ammonia-lyase activity
VAB027_RS01600	COG1278	Cold shock
VAB027_RS01610	COG0557	exoribonuclease II activity
VAB027_RS01615	COG1686	Belongs to the peptidase S11 family
VAB027_RS01625	COG3047	cAMP biosynthetic process
VAB027_RS01635	COG3227	Zinc metalloprotease (Elastase)
VAB027_RS01655	COG2267	carboxylic ester hydrolase activity
VAB027_RS01660	COG2067	long-chain fatty acid transport protein
VAB027_RS01670	COG0366	Alpha amylase catalytic
VAB027_RS01675	COG4989	oxidoreductase activity
VAB027_RS01690	COG1136	(ABC) transporter
VAB027_RS01695	COG0577	efflux transmembrane transporter activity
VAB027_RS01695	COG1136	(ABC) transporter
VAB027_RS01710	COG3275	phosphorelay sensor kinase activity
VAB027_RS01715	COG3279	Response regulator of the LytR AlgR family
VAB027_RS01730	COG0531	amino acid
VAB027_RS01735	COG1252	NADH dehydrogenase
VAB027_RS01775	COG1765	OsmC-like protein
VAB027_RS01780	COG1253	flavin adenine dinucleotide binding
VAB027_RS01805	COG2264	protein methyltransferase activity
VAB027_RS01820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VAB027_RS01825	COG3186	Phenylalanine-4-hydroxylase
VAB027_RS01830	COG2154	pterin-4-alpha-carbinolamine dehydratase
VAB027_RS01835	COG0456	acetyltransferase
VAB027_RS01840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VAB027_RS01845	COG0662	Cupin 2, conserved barrel domain protein
VAB027_RS01850	COG0527	aspartate kinase activity
VAB027_RS01860	COG0459	protein refolding
VAB027_RS01865	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VAB027_RS01870	COG2239	Acts as a magnesium transporter
VAB027_RS01880	COG1166	arginine decarboxylase activity
VAB027_RS01900	COG3397	chitin binding
VAB027_RS01905	COG3046	protein related to deoxyribodipyrimidine photolyase
VAB027_RS01915	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VAB027_RS01930	COG0513	Belongs to the DEAD box helicase family
VAB027_RS01940	COG1368	sulfuric ester hydrolase activity
VAB027_RS01945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VAB027_RS01960	COG0546	phosphoglycolate phosphatase activity
VAB027_RS01975	COG0484	heat shock protein binding
VAB027_RS01995	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VAB027_RS02005	COG4181	ATPase activity
VAB027_RS02010	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VAB027_RS02025	COG1984	allophanate hydrolase subunit 2
VAB027_RS02035	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VAB027_RS02045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VAB027_RS02055	COG0814	amino acid
VAB027_RS02065	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VAB027_RS02070	COG0513	Belongs to the DEAD box helicase family
VAB027_RS02075	COG1309	transcriptional regulator
VAB027_RS02090	COG0494	nUDIX hydrolase
VAB027_RS02100	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VAB027_RS02110	COG1126	abc transporter atp-binding protein
VAB027_RS02115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VAB027_RS02120	COG4215	(ABC) transporter
VAB027_RS02125	COG4160	amino acid transport
VAB027_RS02130	COG0583	DNA-binding transcription factor activity
VAB027_RS02160	COG3118	belongs to the thioredoxin family
VAB027_RS02165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VAB027_RS02170	COG0247	lactate metabolic process
VAB027_RS02175	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
VAB027_RS02180	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VAB027_RS02190	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VAB027_RS02195	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VAB027_RS02210	COG2926	Belongs to the UPF0265 family
VAB027_RS02225	COG2827	Endonuclease containing a URI domain
VAB027_RS02235	COG1879	ABC-type sugar transport system periplasmic component
VAB027_RS02240	COG5002	protein histidine kinase activity
VAB027_RS02240	COG0784	Response regulator, receiver
VAB027_RS02280	COG1618	nucleotide phosphatase activity, acting on free nucleotides
VAB027_RS02285	COG3385	transposase activity
VAB027_RS02300	COG1492	cobalamin metabolic process
VAB027_RS02305	COG0725	ABC transporter, periplasmic molybdate-binding protein
VAB027_RS02310	COG4149	molybdate abc transporter
VAB027_RS02315	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VAB027_RS02345	COG1289	transmembrane transporter activity
VAB027_RS02350	COG0210	DNA helicase
VAB027_RS02355	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VAB027_RS02360	COG1335	isochorismatase
VAB027_RS02365	COG1803	Methylglyoxal synthase
VAB027_RS02370	COG1879	ABC-type sugar transport system periplasmic component
VAB027_RS02375	COG2205	protein histidine kinase activity
VAB027_RS02375	COG0784	Response regulator, receiver
VAB027_RS02375	COG2198	Histidine kinase
VAB027_RS02380	COG0469	pyruvate kinase activity
VAB027_RS02385	COG2271	Major facilitator Superfamily
VAB027_RS02395	COG4191	Histidine kinase
VAB027_RS02410	COG1979	alcohol dehydrogenase
VAB027_RS02420	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VAB027_RS02440	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VAB027_RS02445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VAB027_RS02455	COG0183	Belongs to the thiolase family
VAB027_RS02465	COG3243	poly(R)-hydroxyalkanoic acid synthase
VAB027_RS02470	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VAB027_RS02490	COG0243	molybdopterin cofactor binding
VAB027_RS02500	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VAB027_RS02505	COG3850	Histidine kinase
VAB027_RS02510	COG2197	response regulator
VAB027_RS02515	COG1609	Transcriptional regulator
VAB027_RS02545	COG3069	C4-dicarboxylate transmembrane transporter activity
VAB027_RS02555	COG0840	transmembrane signaling receptor activity
VAB027_RS02560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VAB027_RS02565	COG0545	Peptidyl-prolyl cis-trans isomerase
VAB027_RS02570	COG2885	chlorophyll binding
VAB027_RS02580	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VAB027_RS02585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VAB027_RS02590	COG1621	beta-fructofuranosidase activity
VAB027_RS02595	COG1609	Transcriptional regulator
VAB027_RS02600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VAB027_RS02600	COG1263	PTS System
VAB027_RS02645	COG0446	pyridine nucleotide-disulphide oxidoreductase
VAB027_RS02690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
VAB027_RS02695	COG0583	DNA-binding transcription factor activity
VAB027_RS02720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VAB027_RS02730	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VAB027_RS02755	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VAB027_RS02770	COG2390	Transcriptional regulator
VAB027_RS02775	COG2897	thiosulfate sulfurtransferase activity
VAB027_RS02785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VAB027_RS02795	COG0302	gtp cyclohydrolase
VAB027_RS02800	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VAB027_RS02800	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VAB027_RS02805	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VAB027_RS02810	COG1970	mechanosensitive ion channel activity
VAB027_RS02815	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VAB027_RS02825	COG1011	Hydrolase
VAB027_RS02830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VAB027_RS02835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VAB027_RS02840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VAB027_RS02845	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VAB027_RS02850	COG1840	ABC-type Fe3 transport system, periplasmic component
VAB027_RS02860	COG3842	ATPase activity
VAB027_RS02880	COG3104	oligopeptide transport
VAB027_RS02905	COG4166	transmembrane transport
VAB027_RS02910	COG4174	ABC transporter (Permease)
VAB027_RS02915	COG4239	(ABC) transporter, permease
VAB027_RS02920	COG4172	Belongs to the ABC transporter superfamily
VAB027_RS02925	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VAB027_RS02940	COG0625	glutathione transferase activity
VAB027_RS02960	COG2050	protein possibly involved in aromatic compounds catabolism
VAB027_RS02975	COG4771	TonB-dependent receptor
VAB027_RS02980	COG0583	DNA-binding transcription factor activity
VAB027_RS02985	COG0045	succinate-CoA ligase (ADP-forming) activity
VAB027_RS02985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VAB027_RS02985	COG1042	CoA-binding domain protein
VAB027_RS03005	COG0023	Translation Initiation Factor
VAB027_RS03015	COG3140	Belongs to the UPF0181 family
VAB027_RS03040	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VAB027_RS03045	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VAB027_RS03080	COG2199	diguanylate cyclase activity
VAB027_RS03120	COG2824	Alkylphosphonate utilization operon protein PhnA
VAB027_RS03135	COG0737	Belongs to the 5'-nucleotidase family
VAB027_RS03140	COG3593	DNA synthesis involved in DNA repair
VAB027_RS03150	COG0583	DNA-binding transcription factor activity
VAB027_RS03155	COG2116	formate transmembrane transporter activity
VAB027_RS03165	COG3038	cytochrome b561
VAB027_RS03175	COG2200	EAL domain
VAB027_RS03185	COG0586	Pfam SNARE associated Golgi protein
VAB027_RS03190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VAB027_RS03195	COG0745	RESPONSE REGULATOR receiver
VAB027_RS03200	COG2205	protein histidine kinase activity
VAB027_RS03205	COG0674	pyruvate-flavodoxin oxidoreductase activity
VAB027_RS03205	COG1013	pyruvate-flavodoxin oxidoreductase activity
VAB027_RS03205	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
VAB027_RS03205	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VAB027_RS03210	COG3158	transport of potassium into the cell
VAB027_RS03220	COG0523	cobalamin synthesis protein
VAB027_RS03225	COG0038	chloride channel
VAB027_RS03235	COG0156	8-amino-7-oxononanoate synthase activity
VAB027_RS03240	COG0784	Response regulator, receiver
VAB027_RS03240	COG2205	protein histidine kinase activity
VAB027_RS03245	COG0419	ATPase involved in DNA repair
VAB027_RS03250	COG0420	3'-5' exonuclease activity
VAB027_RS03255	COG1609	Transcriptional regulator
VAB027_RS03260	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VAB027_RS03260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VAB027_RS03265	COG1105	Belongs to the carbohydrate kinase PfkB family
VAB027_RS03270	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VAB027_RS03270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VAB027_RS03270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VAB027_RS03275	COG0189	ligase activity
VAB027_RS03275	COG4067	protein conserved in archaea
VAB027_RS03285	COG0602	queuosine metabolic process
VAB027_RS03290	COG1328	CTP reductase activity
VAB027_RS03340	COG1619	proteins homologs of microcin C7 resistance protein MccF
VAB027_RS03400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VAB027_RS03425	COG4115	mRNA cleavage
VAB027_RS03430	COG2161	toxin-antitoxin pair type II binding
VAB027_RS03445	COG0346	lactoylglutathione lyase activity
VAB027_RS03555	COG0494	nUDIX hydrolase
VAB027_RS03600	COG0346	lactoylglutathione lyase activity
VAB027_RS03670	COG0456	acetyltransferase
VAB027_RS03685	COG2944	sequence-specific DNA binding
VAB027_RS03690	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
VAB027_RS03700	COG1619	proteins homologs of microcin C7 resistance protein MccF
VAB027_RS03745	COG3041	Addiction module toxin RelE StbE family
VAB027_RS03755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VAB027_RS03775	COG3093	addiction module antidote protein HigA
VAB027_RS03780	COG3549	Plasmid maintenance system killer
VAB027_RS03875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VAB027_RS03895	COG0346	lactoylglutathione lyase activity
VAB027_RS03965	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VAB027_RS03970	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VAB027_RS03995	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VAB027_RS04000	COG0509	glycine decarboxylation via glycine cleavage system
VAB027_RS04005	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VAB027_RS04005	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VAB027_RS04025	COG1686	Belongs to the peptidase S11 family
VAB027_RS04040	COG0583	DNA-binding transcription factor activity
VAB027_RS04055	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VAB027_RS04080	COG5002	protein histidine kinase activity
VAB027_RS04085	COG0745	RESPONSE REGULATOR receiver
VAB027_RS04130	COG0561	phosphatase activity
VAB027_RS04135	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
VAB027_RS04140	COG3623	hexulose-6-phosphate isomerase
VAB027_RS04150	COG0745	RESPONSE REGULATOR receiver
VAB027_RS04170	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VAB027_RS04185	COG2207	Transcriptional regulator
VAB027_RS04190	COG4604	ABC transporter, ATP-binding protein
VAB027_RS04195	COG4605	iron ion homeostasis
VAB027_RS04200	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VAB027_RS04225	COG5380	lipid catabolic process
VAB027_RS04230	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VAB027_RS04235	COG0840	transmembrane signaling receptor activity
VAB027_RS04245	COG3240	lipase activity
VAB027_RS04250	COG3706	GGDEF domain
VAB027_RS04265	COG2814	Major facilitator Superfamily
VAB027_RS04270	COG1757	Na H antiporter
VAB027_RS04280	COG4191	Histidine kinase
VAB027_RS04280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VAB027_RS04285	COG0784	Response regulator, receiver
VAB027_RS04285	COG3437	response regulator, receiver
VAB027_RS04295	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VAB027_RS04300	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VAB027_RS04305	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VAB027_RS04310	COG0513	Belongs to the DEAD box helicase family
VAB027_RS04315	COG1204	response to ionizing radiation
VAB027_RS04330	COG0516	GMP reductase activity
VAB027_RS04345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VAB027_RS04355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VAB027_RS04360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VAB027_RS04360	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VAB027_RS04385	COG3036	rescue of stalled ribosome
VAB027_RS04390	COG1278	Cold shock
VAB027_RS04395	COG1017	nitric oxide dioxygenase activity
VAB027_RS04395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VAB027_RS04400	COG3604	Transcriptional regulator
VAB027_RS04410	COG2195	Cleaves the N-terminal amino acid of tripeptides
VAB027_RS04415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VAB027_RS04430	COG0840	transmembrane signaling receptor activity
VAB027_RS04435	COG0714	Associated with various cellular activities
VAB027_RS04455	COG2304	oxidoreductase activity
VAB027_RS04470	COG1278	Cold shock
VAB027_RS04475	COG5001	Diguanylate cyclase
VAB027_RS04475	COG5002	protein histidine kinase activity
VAB027_RS04485	COG3530	Putative quorum-sensing-regulated virulence factor
VAB027_RS04500	COG0814	amino acid
VAB027_RS04505	COG0589	response to stress
VAB027_RS04515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VAB027_RS04515	COG2111	Na H antiporter
VAB027_RS04520	COG1006	Multisubunit Na H antiporter MnhC subunit
VAB027_RS04525	COG0651	ATP synthesis coupled electron transport
VAB027_RS04530	COG1863	multisubunit Na H antiporter MnhE subunit
VAB027_RS04535	COG2212	antiporter activity
VAB027_RS04540	COG1320	monovalent cation:proton antiporter activity
VAB027_RS04545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VAB027_RS04545	COG1017	nitric oxide dioxygenase activity
VAB027_RS04550	COG0242	peptide deformylase activity
VAB027_RS04560	COG0579	oxidoreductase
VAB027_RS04595	COG2271	Major facilitator Superfamily
VAB027_RS04600	COG0584	glycerophosphoryl diester phosphodiesterase
VAB027_RS04610	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VAB027_RS04620	COG1609	Transcriptional regulator
VAB027_RS04625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VAB027_RS04630	COG1879	ABC-type sugar transport system periplasmic component
VAB027_RS04635	COG1172	Belongs to the binding-protein-dependent transport system permease family
VAB027_RS04640	COG1129	ABC transporter
VAB027_RS04645	COG1869	D-ribose catabolic process
VAB027_RS04665	COG3409	Peptidoglycan-binding domain 1 protein
VAB027_RS04665	COG3501	Rhs element vgr protein
VAB027_RS04695	COG3829	transcription factor binding
VAB027_RS04760	COG0564	pseudouridine synthase activity
VAB027_RS04770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VAB027_RS04775	COG2771	luxR family
VAB027_RS04775	COG2200	EAL domain
VAB027_RS04785	COG0673	inositol 2-dehydrogenase activity
VAB027_RS04790	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VAB027_RS04830	COG1342	Belongs to the UPF0251 family
VAB027_RS04840	COG1301	dicarboxylic acid transport
VAB027_RS04865	COG2814	Major facilitator Superfamily
VAB027_RS04870	COG0583	DNA-binding transcription factor activity
VAB027_RS04875	COG3300	MHYT domain
VAB027_RS04875	COG5001	Diguanylate cyclase
VAB027_RS04880	COG0739	heme binding
VAB027_RS04890	COG0659	secondary active sulfate transmembrane transporter activity
VAB027_RS04895	COG3314	Sporulation integral membrane protein YlbJ
VAB027_RS04910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VAB027_RS04915	COG0581	inorganic phosphate transmembrane transporter activity
VAB027_RS04920	COG0573	inorganic phosphate transmembrane transporter activity
VAB027_RS04925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VAB027_RS04955	COG1770	oligopeptidase
VAB027_RS04960	COG0513	Belongs to the DEAD box helicase family
VAB027_RS04975	COG1376	ErfK ybiS ycfS ynhG family protein
VAB027_RS04975	COG1388	LysM domain
VAB027_RS04980	COG0415	Belongs to the DNA photolyase family
VAB027_RS04990	COG3272	Protein of unknown function (DUF1722)
VAB027_RS05000	COG0813	purine-nucleoside phosphorylase activity
VAB027_RS05035	COG0786	glutamate:sodium symporter activity
VAB027_RS05050	COG1999	signal sequence binding
VAB027_RS05060	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VAB027_RS05070	COG0671	phosphoesterase, PA-phosphatase related
VAB027_RS05115	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VAB027_RS05155	COG3501	Rhs element vgr protein
VAB027_RS05165	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VAB027_RS05170	COG1640	4-alpha-glucanotransferase
VAB027_RS05175	COG0058	SHG alpha-glucan phosphorylase activity
VAB027_RS05180	COG2909	trisaccharide binding
VAB027_RS05200	COG2084	Dehydrogenase
VAB027_RS05205	COG0217	transcriptional regulatory protein
VAB027_RS05240	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VAB027_RS05245	COG1444	tRNA N-acetyltransferase activity
VAB027_RS05265	COG4221	oxidoreductase activity
VAB027_RS05280	COG0642	Histidine kinase
VAB027_RS05285	COG2194	sulfuric ester hydrolase activity
VAB027_RS05290	COG4608	Belongs to the ABC transporter superfamily
VAB027_RS05295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VAB027_RS05300	COG0601	transmembrane transport
VAB027_RS05320	COG2198	Histidine kinase
VAB027_RS05320	COG0643	Histidine kinase
VAB027_RS05325	COG0835	chemotaxis
VAB027_RS05330	COG0835	chemotaxis
VAB027_RS05335	COG0840	transmembrane signaling receptor activity
VAB027_RS05340	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VAB027_RS05365	COG0745	RESPONSE REGULATOR receiver
VAB027_RS05410	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VAB027_RS05435	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VAB027_RS05465	COG1982	Orn Lys Arg decarboxylase major
VAB027_RS05470	COG0531	amino acid
VAB027_RS05480	COG1901	pseudouridine methyltransferase
VAB027_RS05490	COG4221	oxidoreductase activity
VAB027_RS05495	COG0840	transmembrane signaling receptor activity
VAB027_RS05505	COG2910	NAD(P)H-binding
VAB027_RS05515	COG1335	isochorismatase
VAB027_RS05530	COG0697	spore germination
VAB027_RS05555	COG0673	inositol 2-dehydrogenase activity
VAB027_RS05560	COG3722	fumarate hydratase activity
VAB027_RS05565	COG0246	Mannitol dehydrogenase
VAB027_RS05570	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VAB027_RS05570	COG2213	PTS system mannitol-specific
VAB027_RS05575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VAB027_RS05580	COG4597	amino acid ABC transporter
VAB027_RS05585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VAB027_RS05595	COG1126	abc transporter atp-binding protein
VAB027_RS05600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VAB027_RS05610	COG0840	transmembrane signaling receptor activity
VAB027_RS05625	COG0840	transmembrane signaling receptor activity
VAB027_RS05640	COG4580	involved in the transport of maltose and maltodextrins
VAB027_RS05655	COG0363	glucosamine-6-phosphate deaminase activity
VAB027_RS05680	COG2259	Doxx family
VAB027_RS05685	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VAB027_RS05690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VAB027_RS05700	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
VAB027_RS05705	COG3366	ferrous iron transmembrane transporter activity
VAB027_RS05710	COG0700	Nucleoside recognition
VAB027_RS05720	COG0697	spore germination
VAB027_RS05725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VAB027_RS05730	COG1764	response to oxidative stress
VAB027_RS05735	COG1846	Transcriptional regulator
VAB027_RS05755	COG2207	Transcriptional regulator
VAB027_RS05760	COG1280	lysine exporter protein (LysE YggA)
VAB027_RS05770	COG1902	pentaerythritol trinitrate reductase activity
VAB027_RS05780	COG1132	(ABC) transporter
VAB027_RS05790	COG1902	pentaerythritol trinitrate reductase activity
VAB027_RS05800	COG0583	DNA-binding transcription factor activity
VAB027_RS05805	COG0513	Belongs to the DEAD box helicase family
VAB027_RS05820	COG0840	transmembrane signaling receptor activity
VAB027_RS05830	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VAB027_RS05845	COG1620	l-lactate permease
VAB027_RS05850	COG0583	DNA-binding transcription factor activity
VAB027_RS05870	COG4172	Belongs to the ABC transporter superfamily
VAB027_RS05880	COG1067	ATP-dependent peptidase activity
VAB027_RS05885	COG0840	transmembrane signaling receptor activity
VAB027_RS05895	COG2211	Major facilitator Superfamily
VAB027_RS05905	COG3123	guanosine phosphorylase activity
VAB027_RS05910	COG1741	Belongs to the pirin family
VAB027_RS05920	COG5001	Diguanylate cyclase
VAB027_RS05925	COG0583	DNA-binding transcription factor activity
VAB027_RS05965	COG3706	GGDEF domain
VAB027_RS05970	COG1846	Transcriptional regulator
VAB027_RS05975	COG0784	Response regulator, receiver
VAB027_RS05975	COG0835	chemotaxis
VAB027_RS05980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VAB027_RS05990	COG0393	Putative heavy-metal-binding
VAB027_RS06005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VAB027_RS06010	COG3842	ATPase activity
VAB027_RS06020	COG1175	transmembrane transport
VAB027_RS06025	COG3833	ABC-type maltose transport systems, permease component
VAB027_RS06040	COG1349	DNA-binding transcription factor activity
VAB027_RS06045	COG2199	diguanylate cyclase activity
VAB027_RS06070	COG1278	Cold shock
VAB027_RS06075	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VAB027_RS06085	COG2354	Protein conserved in bacteria
VAB027_RS06095	COG0418	dihydroorotase activity
VAB027_RS06100	COG0633	Ferredoxin
VAB027_RS06100	COG3217	Mosc domain protein beta barrel domain protein
VAB027_RS06100	COG0633	Ferredoxin
VAB027_RS06100	COG3217	Mosc domain protein beta barrel domain protein
VAB027_RS06135	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VAB027_RS06140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VAB027_RS06145	COG4558	Periplasmic binding protein
VAB027_RS06150	COG0848	biopolymer transport protein
VAB027_RS06155	COG0811	peptide transport
VAB027_RS06160	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VAB027_RS06170	COG3721	Heme iron utilization protein
VAB027_RS06175	COG0748	coenzyme F420 binding
VAB027_RS06185	COG1929	Belongs to the glycerate kinase type-1 family
VAB027_RS06210	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VAB027_RS06215	COG0363	glucosamine-6-phosphate deaminase activity
VAB027_RS06220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VAB027_RS06225	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VAB027_RS06230	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VAB027_RS06250	COG0346	lactoylglutathione lyase activity
VAB027_RS06260	COG2873	o-acetylhomoserine
VAB027_RS06270	COG1063	alcohol dehydrogenase
VAB027_RS06340	COG4626	Terminase
VAB027_RS06340	COG1802	Transcriptional regulator
VAB027_RS06365	COG1278	Cold shock
VAB027_RS06380	COG2351	hydroxyisourate hydrolase activity
VAB027_RS06395	COG3385	transposase activity
VAB027_RS06405	COG3954	Phosphoribulokinase
VAB027_RS06415	COG0429	hydrolase of the alpha beta-hydrolase fold
VAB027_RS06425	COG0488	(ABC) transporter
VAB027_RS06430	COG2249	NAD(P)H dehydrogenase (quinone) activity
VAB027_RS06445	COG1047	Peptidyl-prolyl cis-trans
VAB027_RS06455	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VAB027_RS06460	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VAB027_RS06465	COG3083	sulfuric ester hydrolase activity
VAB027_RS06470	COG0557	exoribonuclease II activity
VAB027_RS06475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VAB027_RS06480	COG0051	transcription antitermination factor activity, RNA binding
VAB027_RS06485	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VAB027_RS06490	COG0088	Forms part of the polypeptide exit tunnel
VAB027_RS06495	COG0089	rRNA binding
VAB027_RS06500	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VAB027_RS06505	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VAB027_RS06510	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VAB027_RS06515	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VAB027_RS06520	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VAB027_RS06525	COG0255	Belongs to the universal ribosomal protein uL29 family
VAB027_RS06530	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VAB027_RS06535	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VAB027_RS06540	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VAB027_RS06545	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VAB027_RS06550	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VAB027_RS06555	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VAB027_RS06560	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VAB027_RS06565	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VAB027_RS06570	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VAB027_RS06575	COG1841	ribosomal large subunit assembly
VAB027_RS06585	COG0201	protein transport
VAB027_RS06590	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VAB027_RS06595	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VAB027_RS06600	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VAB027_RS06605	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VAB027_RS06610	COG0202	RNA polymerase activity
VAB027_RS06615	COG0203	ribosomal protein L17
VAB027_RS06625	COG0545	Peptidyl-prolyl cis-trans isomerase
VAB027_RS06630	COG3266	domain, Protein
VAB027_RS06630	COG3061	Opacity-associated protein A
VAB027_RS06635	COG0697	spore germination
VAB027_RS06640	COG2153	protein acetylation
VAB027_RS06645	COG0513	Belongs to the DEAD box helicase family
VAB027_RS06655	COG0737	Belongs to the 5'-nucleotidase family
VAB027_RS06660	COG1648	precorrin-2 dehydrogenase activity
VAB027_RS06660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VAB027_RS06665	COG0175	sulfate reduction
VAB027_RS06670	COG2895	sulfate adenylyltransferase (ATP) activity
VAB027_RS06675	COG0529	Catalyzes the synthesis of activated sulfate
VAB027_RS06695	COG1136	(ABC) transporter
VAB027_RS06710	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VAB027_RS06715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VAB027_RS06720	COG0729	surface antigen
VAB027_RS06730	COG2105	PFAM AIG2 family protein
VAB027_RS06735	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VAB027_RS06750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VAB027_RS06755	COG0163	prenyltransferase activity
VAB027_RS06765	COG1178	ABC-type Fe3 transport system permease component
VAB027_RS06770	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VAB027_RS06775	COG3028	Belongs to the UPF0307 family
VAB027_RS06780	COG0312	modulator of DNA gyrase
VAB027_RS06785	COG2239	Acts as a magnesium transporter
VAB027_RS06790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VAB027_RS06795	COG1660	Displays ATPase and GTPase activities
VAB027_RS06800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VAB027_RS06805	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VAB027_RS06815	COG1137	ATPase activity
VAB027_RS06820	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VAB027_RS06835	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VAB027_RS06835	COG0517	IMP dehydrogenase activity
VAB027_RS06850	COG1127	ABC transporter
VAB027_RS06855	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VAB027_RS06860	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VAB027_RS06865	COG2854	intermembrane phospholipid transfer
VAB027_RS06875	COG5007	Belongs to the BolA IbaG family
VAB027_RS06880	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VAB027_RS06890	COG0251	oxidation-reduction process
VAB027_RS06900	COG0540	Belongs to the ATCase OTCase family
VAB027_RS06910	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VAB027_RS06925	COG0564	pseudouridine synthase activity
VAB027_RS06930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VAB027_RS06935	COG0525	valine-tRNA ligase activity
VAB027_RS06940	COG2927	DNA polymerase III (CHI subunit)
VAB027_RS06945	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VAB027_RS06950	COG0795	lipopolysaccharide-transporting ATPase activity
VAB027_RS06955	COG0795	lipopolysaccharide-transporting ATPase activity
VAB027_RS06970	COG3437	response regulator, receiver
VAB027_RS07015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VAB027_RS07020	COG0826	peptidase U32
VAB027_RS07030	COG0745	RESPONSE REGULATOR receiver
VAB027_RS07035	COG5002	protein histidine kinase activity
VAB027_RS07045	COG0248	Ppx GppA phosphatase
VAB027_RS07050	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VAB027_RS07060	COG0581	inorganic phosphate transmembrane transporter activity
VAB027_RS07065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VAB027_RS07080	COG3142	Participates in the control of copper homeostasis
VAB027_RS07085	COG0450	alkyl hydroperoxide reductase
VAB027_RS07090	COG0583	DNA-binding transcription factor activity
VAB027_RS07095	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VAB027_RS07105	COG0517	IMP dehydrogenase activity
VAB027_RS07110	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VAB027_RS07125	COG1862	Preprotein translocase
VAB027_RS07130	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VAB027_RS07135	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VAB027_RS07140	COG0483	inositol monophosphate 1-phosphatase activity
VAB027_RS07155	COG1104	cysteine desulfurase activity
VAB027_RS07160	COG0822	iron-sulfur transferase activity
VAB027_RS07180	COG0633	Ferredoxin
VAB027_RS07185	COG2975	iron-sulfur cluster assembly
VAB027_RS07190	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VAB027_RS07195	COG0105	UTP biosynthetic process
VAB027_RS07205	COG1426	Protein conserved in bacteria
VAB027_RS07210	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VAB027_RS07215	COG0124	histidyl-tRNA synthetase
VAB027_RS07220	COG2976	Protein conserved in bacteria
VAB027_RS07225	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VAB027_RS07230	COG1160	GTP binding
VAB027_RS07245	COG1570	exodeoxyribonuclease VII activity
VAB027_RS07250	COG0517	IMP dehydrogenase activity
VAB027_RS07250	COG0516	GMP reductase activity
VAB027_RS07255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VAB027_RS07255	COG0519	Catalyzes the synthesis of GMP from XMP
VAB027_RS07265	COG1584	GPR1 FUN34 yaaH family protein
VAB027_RS07270	COG3433	isochorismatase activity
VAB027_RS07270	COG1535	isochorismatase
VAB027_RS07275	COG1021	2,3-dihydroxybenzoate-AMP ligase
VAB027_RS07280	COG1169	isochorismate synthase
VAB027_RS07285	COG1028	Short-chain dehydrogenase reductase Sdr
VAB027_RS07295	COG4592	Periplasmic binding protein
VAB027_RS07300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VAB027_RS07305	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VAB027_RS07310	COG1120	ATPase activity
VAB027_RS07315	COG2977	Belongs to the P-Pant transferase superfamily
VAB027_RS07320	COG1115	amino acid carrier protein
VAB027_RS07345	COG4565	transcriptional regulatory protein
VAB027_RS07355	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VAB027_RS07360	COG5016	pyruvate
VAB027_RS07360	COG0511	ligase activity, forming carbon-carbon bonds
VAB027_RS07365	COG3630	sodium ion export across plasma membrane
VAB027_RS07375	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
VAB027_RS07380	COG3052	prosthetic group binding
VAB027_RS07385	COG2301	Belongs to the HpcH HpaI aldolase family
VAB027_RS07390	COG3051	citrate lyase alpha subunit
VAB027_RS07410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VAB027_RS07415	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VAB027_RS07420	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VAB027_RS07435	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VAB027_RS07440	COG0732	type I restriction modification DNA specificity domain
VAB027_RS07445	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VAB027_RS07465	COG1396	sequence-specific DNA binding
VAB027_RS07515	COG0328	RNA-DNA hybrid ribonuclease activity
VAB027_RS07590	COG0582	viral genome integration into host DNA
VAB027_RS07595	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VAB027_RS07600	COG2867	negative regulation of translational initiation
VAB027_RS07605	COG2914	Belongs to the UPF0125 (RnfH) family
VAB027_RS07610	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VAB027_RS07615	COG0497	DNA recombination
VAB027_RS07620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VAB027_RS07625	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VAB027_RS07630	COG0443	Heat shock 70 kDa protein
VAB027_RS07635	COG0484	heat shock protein binding
VAB027_RS07670	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VAB027_RS07685	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VAB027_RS07695	COG0047	phosphoribosylformylglycinamidine synthase activity
VAB027_RS07695	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VAB027_RS07720	COG0442	prolyl-tRNA aminoacylation
VAB027_RS07725	COG1720	tRNA m6t6A37 methyltransferase activity
VAB027_RS07730	COG0254	rRNA binding
VAB027_RS07735	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VAB027_RS07740	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VAB027_RS07745	COG1671	Belongs to the UPF0178 family
VAB027_RS07755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VAB027_RS07765	COG3385	transposase activity
VAB027_RS07775	COG3098	single-species biofilm formation
VAB027_RS07780	COG0564	pseudouridine synthase activity
VAB027_RS07785	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VAB027_RS07790	COG0142	geranyltranstransferase activity
VAB027_RS07795	COG1722	exodeoxyribonuclease VII activity
VAB027_RS07800	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VAB027_RS07810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VAB027_RS07810	COG0301	tRNA thio-modification
VAB027_RS07820	COG0583	DNA-binding transcription factor activity
VAB027_RS07825	COG2363	Small membrane protein
VAB027_RS07830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VAB027_RS07835	COG1611	Belongs to the LOG family
VAB027_RS07850	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VAB027_RS07850	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VAB027_RS07860	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VAB027_RS07865	COG1464	Belongs to the NlpA lipoprotein family
VAB027_RS07870	COG2011	ABC-type metal ion transport system permease component
VAB027_RS07875	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VAB027_RS07880	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VAB027_RS07885	COG1609	Transcriptional regulator
VAB027_RS07890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VAB027_RS07890	COG1263	PTS System
VAB027_RS07895	COG0366	Alpha amylase catalytic
VAB027_RS07920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VAB027_RS07930	COG2932	Transcriptional regulator
VAB027_RS07935	COG3423	Transcriptional regulator
VAB027_RS07940	COG2801	Transposase and inactivated derivatives
VAB027_RS07945	COG2842	Transposition protein
VAB027_RS08055	COG0640	Transcriptional regulator
VAB027_RS08065	COG4373	Mu-like prophage FluMu protein gp28
VAB027_RS08070	COG4383	Mu-like prophage protein gp29
VAB027_RS08095	COG4397	Mu-like prophage major head subunit gpT
VAB027_RS08105	COG4387	Mu-like prophage protein GP36
VAB027_RS08125	COG4386	tail sheath protein
VAB027_RS08135	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
VAB027_RS08155	COG4384	Bacteriophage Mu Gp45 protein
VAB027_RS08165	COG3299	homolog of phage Mu protein gp47
VAB027_RS08170	COG3778	Protein conserved in bacteria
VAB027_RS08190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VAB027_RS08195	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VAB027_RS08200	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VAB027_RS08225	COG1045	serine acetyltransferase
VAB027_RS08235	COG0438	transferase activity, transferring glycosyl groups
VAB027_RS08245	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
VAB027_RS08275	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VAB027_RS08285	COG1596	polysaccharide export
VAB027_RS08310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VAB027_RS08320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VAB027_RS08325	COG0321	lipoyl(octanoyl) transferase activity
VAB027_RS08330	COG2921	Belongs to the UPF0250 family
VAB027_RS08340	COG1686	Belongs to the peptidase S11 family
VAB027_RS08345	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VAB027_RS08350	COG0772	Belongs to the SEDS family
VAB027_RS08355	COG0768	penicillin binding
VAB027_RS08360	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VAB027_RS08365	COG0799	negative regulation of ribosome biogenesis
VAB027_RS08370	COG1466	dna polymerase III delta subunit
VAB027_RS08375	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VAB027_RS08380	COG0495	leucyl-tRNA aminoacylation
VAB027_RS08385	COG2888	peptidyl-tyrosine sulfation
VAB027_RS08390	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VAB027_RS08395	COG4535	Mg2 and Co2 transporter CorC
VAB027_RS08400	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VAB027_RS08405	COG1702	phosphate starvation-inducible protein PhoH
VAB027_RS08410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VAB027_RS08415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VAB027_RS08420	COG2190	(PTS) system
VAB027_RS08430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VAB027_RS08440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VAB027_RS08445	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VAB027_RS08450	COG3115	cell septum assembly
VAB027_RS08455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VAB027_RS08465	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VAB027_RS08470	COG0789	Transcriptional regulator
VAB027_RS08475	COG1585	Membrane protein implicated in regulation of membrane protease activity
VAB027_RS08480	COG0330	HflC and HflK could
VAB027_RS08485	COG3118	belongs to the thioredoxin family
VAB027_RS08490	COG0300	oxidoreductase activity
VAB027_RS08495	COG1090	epimerase
VAB027_RS08500	COG0622	Phosphoesterase
VAB027_RS08515	COG3710	Transcriptional regulator
VAB027_RS08520	COG0326	Molecular chaperone. Has ATPase activity
VAB027_RS08525	COG0563	adenylate kinase activity
VAB027_RS08530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VAB027_RS08545	COG0367	asparagine synthase
VAB027_RS08550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VAB027_RS08550	COG4651	solute:proton antiporter activity
VAB027_RS08555	COG1940	carbohydrate kinase activity
VAB027_RS08555	COG1846	Transcriptional regulator
VAB027_RS08560	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VAB027_RS08565	COG1263	PTS System
VAB027_RS08565	COG2190	(PTS) system
VAB027_RS08565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VAB027_RS08580	COG0101	tRNA pseudouridine synthase activity
VAB027_RS08585	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VAB027_RS08590	COG0285	dihydrofolate synthase activity
VAB027_RS08595	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VAB027_RS08600	COG1286	toxin biosynthetic process
VAB027_RS08605	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VAB027_RS08610	COG2056	Na+-H+ antiporter family
VAB027_RS08615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VAB027_RS08635	COG0346	lactoylglutathione lyase activity
VAB027_RS08640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VAB027_RS08645	COG4660	Part of a membrane complex involved in electron transport
VAB027_RS08660	COG4656	Part of a membrane complex involved in electron transport
VAB027_RS08665	COG2878	Part of a membrane complex involved in electron transport
VAB027_RS08670	COG4657	Part of a membrane complex involved in electron transport
VAB027_RS08680	COG0556	nucleotide-excision repair
VAB027_RS08690	COG2204	response regulator
VAB027_RS08695	COG2198	Histidine kinase
VAB027_RS08700	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VAB027_RS08705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VAB027_RS08710	COG0521	Mo-molybdopterin cofactor biosynthetic process
VAB027_RS08715	COG0315	cyclic pyranopterin monophosphate synthase activity
VAB027_RS08720	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VAB027_RS08725	COG0314	molybdopterin synthase activity
VAB027_RS08730	COG2199	diguanylate cyclase activity
VAB027_RS08735	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
VAB027_RS08735	COG0617	tRNA 3'-terminal CCA addition
VAB027_RS08735	COG0517	IMP dehydrogenase activity
VAB027_RS08750	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VAB027_RS08760	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VAB027_RS08760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VAB027_RS08765	COG0489	protein tyrosine kinase activity
VAB027_RS08775	COG0572	uridine kinase
VAB027_RS08780	COG2982	Protein involved in outer membrane biogenesis
VAB027_RS08785	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VAB027_RS08790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VAB027_RS08800	COG2067	long-chain fatty acid transport protein
VAB027_RS08820	COG0183	Belongs to the thiolase family
VAB027_RS08825	COG1024	Enoyl-CoA hydratase
VAB027_RS08825	COG1250	3-hydroxyacyl-CoA dehydrogenase
VAB027_RS08830	COG0778	Nitroreductase
VAB027_RS08835	COG0583	DNA-binding transcription factor activity
VAB027_RS08840	COG0745	RESPONSE REGULATOR receiver
VAB027_RS08850	COG2832	Protein of unknown function (DUF454)
VAB027_RS08855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VAB027_RS08860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
VAB027_RS08865	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VAB027_RS08870	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VAB027_RS08880	COG2983	Belongs to the UPF0260 family
VAB027_RS08890	COG1028	Short-chain dehydrogenase reductase Sdr
VAB027_RS08895	COG0616	signal peptide processing
VAB027_RS08905	COG1522	sequence-specific DNA binding
VAB027_RS08910	COG1946	Acyl-CoA thioesterase
VAB027_RS08930	COG3706	GGDEF domain
VAB027_RS08935	COG0640	Transcriptional regulator
VAB027_RS08940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VAB027_RS08965	COG1881	PFAM PEBP family protein
VAB027_RS08985	COG0009	L-threonylcarbamoyladenylate synthase
VAB027_RS09000	COG2201	protein-glutamate methylesterase activity
VAB027_RS09010	COG5002	protein histidine kinase activity
VAB027_RS09015	COG4191	Histidine kinase
VAB027_RS09020	COG5001	Diguanylate cyclase
VAB027_RS09020	COG3300	MHYT domain
VAB027_RS09025	COG2204	response regulator
VAB027_RS09045	COG0601	transmembrane transport
VAB027_RS09050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VAB027_RS09055	COG0444	Belongs to the ABC transporter superfamily
VAB027_RS09060	COG4608	Belongs to the ABC transporter superfamily
VAB027_RS09065	COG0435	Glutathione S-transferase
VAB027_RS09070	COG0857	belongs to the CobB CobQ family
VAB027_RS09070	COG0280	phosphate acetyltransferase
VAB027_RS09075	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VAB027_RS09080	COG3092	negative regulation of chromosome organization
VAB027_RS09085	COG4628	conserved protein (DUF2132)
VAB027_RS09095	COG4120	Belongs to the binding-protein-dependent transport system permease family
VAB027_RS09105	COG3706	GGDEF domain
VAB027_RS09110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VAB027_RS09115	COG0653	protein targeting
VAB027_RS09120	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VAB027_RS09125	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VAB027_RS09130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VAB027_RS09140	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VAB027_RS09145	COG0156	8-amino-7-oxononanoate synthase activity
VAB027_RS09150	COG2226	methyltransferase
VAB027_RS09155	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VAB027_RS09165	COG0501	Belongs to the peptidase M48B family
VAB027_RS09175	COG0300	oxidoreductase activity
VAB027_RS09190	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VAB027_RS09200	COG2268	Band 7 protein
VAB027_RS09210	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VAB027_RS09215	COG2915	High frequency lysogenization protein hflD homolog
VAB027_RS09220	COG0482	sulfurtransferase activity
VAB027_RS09225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VAB027_RS09230	COG2916	Histone family protein nucleoid-structuring protein H-NS
VAB027_RS09235	COG1757	Na H antiporter
VAB027_RS09240	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VAB027_RS09245	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VAB027_RS09250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VAB027_RS09255	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VAB027_RS09255	COG0131	Imidazoleglycerol-phosphate dehydratase
VAB027_RS09260	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VAB027_RS09265	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VAB027_RS09270	COG0107	imidazoleglycerol-phosphate synthase activity
VAB027_RS09275	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VAB027_RS09275	COG0140	phosphoribosyl-ATP diphosphatase activity
VAB027_RS09280	COG1187	pseudouridine synthase activity
VAB027_RS09290	COG1278	Cold shock
VAB027_RS09295	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VAB027_RS09300	COG0542	response to heat
VAB027_RS09305	COG2985	domain, Protein
VAB027_RS09305	COG3273	potassium ion transport
VAB027_RS09310	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VAB027_RS09315	COG1454	alcohol dehydrogenase
VAB027_RS09315	COG1012	belongs to the aldehyde dehydrogenase family
VAB027_RS09320	COG1737	Transcriptional regulator
VAB027_RS09325	COG0076	glutamate decarboxylase activity
VAB027_RS09335	COG2431	L-lysine efflux transmembrane transporter activity
VAB027_RS09345	COG3070	regulator of competence-specific genes
VAB027_RS09360	COG3852	Histidine kinase
VAB027_RS09370	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VAB027_RS09385	COG0189	ligase activity
VAB027_RS09385	COG4067	protein conserved in archaea
VAB027_RS09390	COG0500	methyltransferase
VAB027_RS09395	COG4106	trans-aconitate 2-methyltransferase activity
VAB027_RS09400	COG1801	Protein of unknown function DUF72
VAB027_RS09405	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VAB027_RS09410	COG1435	thymidine kinase activity
VAB027_RS09420	COG0159	tryptophan synthase activity
VAB027_RS09425	COG0133	tryptophan synthase activity
VAB027_RS09430	COG0134	indole-3-glycerol-phosphate synthase activity
VAB027_RS09430	COG0135	phosphoribosylanthranilate isomerase activity
VAB027_RS09440	COG0512	Glutamine amidotransferase of anthranilate synthase
VAB027_RS09445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VAB027_RS09455	COG0613	PHP domain protein
VAB027_RS09460	COG0009	L-threonylcarbamoyladenylate synthase
VAB027_RS09465	COG1187	pseudouridine synthase activity
VAB027_RS09470	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VAB027_RS09475	COG4988	ABC transporter
VAB027_RS09480	COG0492	ferredoxin-NADP+ reductase activity
VAB027_RS09490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VAB027_RS09495	COG3706	GGDEF domain
VAB027_RS09500	COG2949	membrane
VAB027_RS09510	COG0281	malic enzyme
VAB027_RS09520	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VAB027_RS09540	COG2885	chlorophyll binding
VAB027_RS09555	COG0247	lactate metabolic process
VAB027_RS09555	COG0277	FAD linked oxidase domain protein
VAB027_RS09575	COG2986	histidine ammonia-lyase
VAB027_RS09580	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VAB027_RS09585	COG0010	Belongs to the arginase family
VAB027_RS09590	COG1228	amidohydrolase
VAB027_RS09605	COG3099	Belongs to the UPF0263 family
VAB027_RS09610	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VAB027_RS09620	COG5001	Diguanylate cyclase
VAB027_RS09625	COG0417	DNA replication proofreading
VAB027_RS09630	COG2197	response regulator
VAB027_RS09635	COG0322	excinuclease ABC activity
VAB027_RS09680	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VAB027_RS09685	COG0072	phenylalanine-tRNA ligase activity
VAB027_RS09685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VAB027_RS09690	COG0776	regulation of translation
VAB027_RS09730	COG1346	cytolysis
VAB027_RS09735	COG1380	Effector of murein hydrolase LrgA
VAB027_RS09740	COG2925	Exonuclease
VAB027_RS09745	COG1823	symporter activity
VAB027_RS09750	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VAB027_RS09755	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VAB027_RS09760	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VAB027_RS09775	COG2988	succinylglutamate desuccinylase activity
VAB027_RS09780	COG4139	cobalamin transport
VAB027_RS09785	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VAB027_RS09830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VAB027_RS09835	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VAB027_RS09840	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VAB027_RS09850	COG1054	Belongs to the UPF0176 family
VAB027_RS09860	COG2814	Major facilitator Superfamily
VAB027_RS09870	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VAB027_RS09900	COG3108	Peptidase M15
VAB027_RS09905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VAB027_RS09920	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VAB027_RS09945	COG1846	Transcriptional regulator
VAB027_RS09950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VAB027_RS09955	COG0726	polysaccharide deacetylase
VAB027_RS09960	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VAB027_RS09970	COG1447	Phosphotransferase system cellobiose-specific component IIA
VAB027_RS09975	COG1486	melibiose metabolic process
VAB027_RS09980	COG3394	polysaccharide catabolic process
VAB027_RS09985	COG1609	Transcriptional regulator
VAB027_RS09990	COG2943	transferase activity, transferring hexosyl groups
VAB027_RS09995	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
VAB027_RS10000	COG0840	transmembrane signaling receptor activity
VAB027_RS10020	COG1448	Aminotransferase
VAB027_RS10025	COG2770	Histidine kinase
VAB027_RS10025	COG3437	response regulator, receiver
VAB027_RS10030	COG0351	phosphomethylpyrimidine kinase
VAB027_RS10035	COG0017	Asparaginyl-tRNA synthetase
VAB027_RS10045	COG0720	synthase
VAB027_RS10050	COG1760	l-serine dehydratase
VAB027_RS10055	COG0814	amino acid
VAB027_RS10060	COG0494	nUDIX hydrolase
VAB027_RS10065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VAB027_RS10080	COG3106	COG3106 Predicted ATPase
VAB027_RS10085	COG3768	UPF0283 membrane protein
VAB027_RS10095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VAB027_RS10110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VAB027_RS10120	COG0471	metal ion transport
VAB027_RS10125	COG4191	Histidine kinase
VAB027_RS10125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VAB027_RS10135	COG2990	Protein conserved in bacteria
VAB027_RS10140	COG3713	MltA-interacting MipA family protein
VAB027_RS10145	COG5002	protein histidine kinase activity
VAB027_RS10150	COG0745	RESPONSE REGULATOR receiver
VAB027_RS10185	COG1129	ABC transporter
VAB027_RS10205	COG1566	PFAM secretion protein HlyD family protein
VAB027_RS10245	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VAB027_RS10250	COG0372	Belongs to the citrate synthase family
VAB027_RS10280	COG2195	Cleaves the N-terminal amino acid of tripeptides
VAB027_RS10290	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VAB027_RS10300	COG0625	glutathione transferase activity
VAB027_RS10305	COG3437	response regulator, receiver
VAB027_RS10325	COG3706	GGDEF domain
VAB027_RS10330	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VAB027_RS10335	COG1254	Belongs to the acylphosphatase family
VAB027_RS10340	COG2920	part of a sulfur-relay system
VAB027_RS10345	COG0670	Belongs to the BI1 family
VAB027_RS10350	COG1126	abc transporter atp-binding protein
VAB027_RS10355	COG0765	amino acid transport
VAB027_RS10360	COG4597	amino acid ABC transporter
VAB027_RS10365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VAB027_RS10375	COG0561	phosphatase activity
VAB027_RS10380	COG0602	queuosine metabolic process
VAB027_RS10385	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VAB027_RS10415	COG3706	GGDEF domain
VAB027_RS10420	COG0443	Heat shock 70 kDa protein
VAB027_RS10465	COG1643	Atp-dependent helicase
VAB027_RS10480	COG0095	Lipoate-protein ligase
VAB027_RS10485	COG0402	S-adenosylhomocysteine deaminase activity
VAB027_RS10495	COG0583	DNA-binding transcription factor activity
VAB027_RS10500	COG0477	Major facilitator Superfamily
VAB027_RS10505	COG0415	Belongs to the DNA photolyase family
VAB027_RS10520	COG0745	RESPONSE REGULATOR receiver
VAB027_RS10530	COG2198	Histidine kinase
VAB027_RS10530	COG0643	Histidine kinase
VAB027_RS10535	COG0643	Histidine kinase
VAB027_RS10535	COG0784	Response regulator, receiver
VAB027_RS10535	COG2198	Histidine kinase
VAB027_RS10540	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VAB027_RS10550	COG2201	protein-glutamate methylesterase activity
VAB027_RS10555	COG0835	chemotaxis
VAB027_RS10560	COG0840	transmembrane signaling receptor activity
VAB027_RS10560	COG3290	protein histidine kinase activity
VAB027_RS10565	COG0840	transmembrane signaling receptor activity
VAB027_RS10575	COG0513	Belongs to the DEAD box helicase family
VAB027_RS10585	COG1538	Outer membrane efflux protein
VAB027_RS10590	COG1566	PFAM secretion protein HlyD family protein
VAB027_RS10595	COG2814	Major facilitator Superfamily
VAB027_RS10600	COG0840	transmembrane signaling receptor activity
VAB027_RS10605	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VAB027_RS10615	COG3501	Rhs element vgr protein
VAB027_RS10635	COG1280	lysine exporter protein (LysE YggA)
VAB027_RS10640	COG1115	amino acid carrier protein
VAB027_RS10655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VAB027_RS10665	COG1177	transmembrane transport
VAB027_RS10675	COG3842	ATPase activity
VAB027_RS10695	COG0037	tRNA processing
VAB027_RS10700	COG0589	response to stress
VAB027_RS10705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VAB027_RS10720	COG2217	Heavy metal translocating P-type atpase
VAB027_RS10730	COG2010	Cytochrome c
VAB027_RS10745	COG3278	Belongs to the heme-copper respiratory oxidase family
VAB027_RS10760	COG2205	protein histidine kinase activity
VAB027_RS10760	COG0784	Response regulator, receiver
VAB027_RS10785	COG2994	toxin metabolic process
VAB027_RS10790	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VAB027_RS10790	COG3064	Membrane
VAB027_RS10790	COG1073	alpha beta
VAB027_RS10805	COG3120	sequence-specific DNA binding
VAB027_RS10810	COG1067	ATP-dependent peptidase activity
VAB027_RS10815	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VAB027_RS10830	COG0488	(ABC) transporter
VAB027_RS10850	COG0167	dihydroorotate dehydrogenase activity
VAB027_RS10865	COG0308	aminopeptidase N
VAB027_RS10880	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VAB027_RS10885	COG1956	GAF domain-containing protein
VAB027_RS10890	COG1132	(ABC) transporter
VAB027_RS10895	COG2995	paraquat-inducible protein a
VAB027_RS10900	COG3008	intermembrane lipid transfer
VAB027_RS10910	COG2996	Protein conserved in bacteria
VAB027_RS10925	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VAB027_RS10930	COG1666	GTP binding
VAB027_RS10935	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VAB027_RS10950	COG0437	4 iron, 4 sulfur cluster binding
VAB027_RS10955	COG0243	molybdopterin cofactor binding
VAB027_RS10955	COG3383	formate dehydrogenase (NAD+) activity
VAB027_RS10985	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VAB027_RS10990	COG0488	(ABC) transporter
VAB027_RS10995	COG3852	Histidine kinase
VAB027_RS11000	COG2204	response regulator
VAB027_RS11010	COG4662	Binding-protein-dependent transport system inner membrane component
VAB027_RS11015	COG3842	ATPase activity
VAB027_RS11020	COG0746	molybdenum cofactor guanylyltransferase activity
VAB027_RS11025	COG0303	'Molybdopterin
VAB027_RS11035	COG1940	carbohydrate kinase activity
VAB027_RS11040	COG3148	PFAM DTW domain containing protein
VAB027_RS11050	COG3290	protein histidine kinase activity
VAB027_RS11050	COG0840	transmembrane signaling receptor activity
VAB027_RS11055	COG0791	NLP P60 protein
VAB027_RS11065	COG3001	Fructosamine kinase
VAB027_RS11075	COG0534	Mate efflux family protein
VAB027_RS11085	COG1793	dna ligase
VAB027_RS11095	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VAB027_RS11100	COG0848	biopolymer transport protein
VAB027_RS11105	COG0811	peptide transport
VAB027_RS11110	COG0811	peptide transport
VAB027_RS11125	COG1175	transmembrane transport
VAB027_RS11130	COG0395	ABC-type sugar transport system, permease component
VAB027_RS11135	COG3842	ATPase activity
VAB027_RS11140	COG1349	DNA-binding transcription factor activity
VAB027_RS11145	COG0584	glycerophosphoryl diester phosphodiesterase
VAB027_RS11150	COG2731	YhcH YjgK YiaL family protein
VAB027_RS11155	COG0251	oxidation-reduction process
VAB027_RS11160	COG1609	Transcriptional regulator
VAB027_RS11165	COG2723	6-phospho-beta-galactosidase activity
VAB027_RS11195	COG1136	(ABC) transporter
VAB027_RS11195	COG0577	efflux transmembrane transporter activity
VAB027_RS11200	COG1136	(ABC) transporter
VAB027_RS11200	COG0577	efflux transmembrane transporter activity
VAB027_RS11205	COG4591	ABC-type transport system involved in lipoprotein release permease component
VAB027_RS11205	COG1136	(ABC) transporter
VAB027_RS11210	COG1294	oxidase, subunit
VAB027_RS11215	COG1271	oxidase subunit
VAB027_RS11240	COG3097	Belongs to the UPF0267 family
VAB027_RS11260	COG0583	DNA-binding transcription factor activity
VAB027_RS11265	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VAB027_RS11285	COG0753	catalase activity
VAB027_RS11305	COG0693	protein deglycase activity
VAB027_RS11310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VAB027_RS11320	COG0346	lactoylglutathione lyase activity
VAB027_RS11330	COG3527	Alpha-acetolactate decarboxylase
VAB027_RS11345	COG2199	diguanylate cyclase activity
VAB027_RS11345	COG2200	EAL domain
VAB027_RS11355	COG2017	converts alpha-aldose to the beta-anomer
VAB027_RS11360	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VAB027_RS11365	COG1085	galactose-1-phosphate uridylyltransferase
VAB027_RS11405	COG0784	Response regulator, receiver
VAB027_RS11405	COG0835	chemotaxis
VAB027_RS11415	COG4565	transcriptional regulatory protein
VAB027_RS11420	COG3290	protein histidine kinase activity
VAB027_RS11435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VAB027_RS11455	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VAB027_RS11460	COG3063	Type IV pilus biogenesis stability protein PilW
VAB027_RS11475	COG1451	nucleotide metabolic process
VAB027_RS11485	COG0583	DNA-binding transcription factor activity
VAB027_RS11505	COG1538	Outer membrane efflux protein
VAB027_RS11520	COG1748	Saccharopine dehydrogenase
VAB027_RS11530	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VAB027_RS11540	COG0577	efflux transmembrane transporter activity
VAB027_RS11545	COG4181	ATPase activity
VAB027_RS11550	COG0534	Mate efflux family protein
VAB027_RS11555	COG0702	epimerase
VAB027_RS11565	COG2814	Major facilitator Superfamily
VAB027_RS11570	COG1187	pseudouridine synthase activity
VAB027_RS11575	COG1061	Type III restriction enzyme res subunit
VAB027_RS11595	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VAB027_RS11600	COG3706	GGDEF domain
VAB027_RS11600	COG4251	negative regulation of phosphorylation
VAB027_RS11600	COG5001	Diguanylate cyclase
VAB027_RS11600	COG2203	Gaf domain
VAB027_RS11615	COG0840	transmembrane signaling receptor activity
VAB027_RS11630	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
VAB027_RS11650	COG4934	collagen metabolic process
VAB027_RS11665	COG2205	protein histidine kinase activity
VAB027_RS11665	COG0784	Response regulator, receiver
VAB027_RS11670	COG2239	Acts as a magnesium transporter
VAB027_RS11680	COG0814	amino acid
VAB027_RS11685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VAB027_RS11690	COG1131	(ABC) transporter
VAB027_RS11695	COG0842	Transport permease protein
VAB027_RS11705	COG3313	Fe-S protein
VAB027_RS11715	COG4134	Bacterial extracellular solute-binding protein
VAB027_RS11720	COG4135	transport system, permease component
VAB027_RS11725	COG4136	ATPase activity
VAB027_RS11730	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VAB027_RS11735	COG0564	pseudouridine synthase activity
VAB027_RS11740	COG0733	neurotransmitter:sodium symporter activity
VAB027_RS11755	COG2818	Glycosylase
VAB027_RS11770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VAB027_RS11785	COG1842	Phage shock protein A
VAB027_RS11790	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VAB027_RS11800	COG4168	peptide transport system, permease
VAB027_RS11815	COG4172	Belongs to the ABC transporter superfamily
VAB027_RS11830	COG1227	inorganic diphosphatase activity
VAB027_RS11850	COG3005	denitrification pathway
VAB027_RS11855	COG4459	periplasmic nitrate reductase
VAB027_RS11865	COG2116	formate transmembrane transporter activity
VAB027_RS11875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VAB027_RS11880	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VAB027_RS11895	COG1607	acyl-coa hydrolase
VAB027_RS11900	COG2350	Protein conserved in bacteria
VAB027_RS11910	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VAB027_RS11915	COG0583	DNA-binding transcription factor activity
VAB027_RS11930	COG0612	Peptidase, M16
VAB027_RS11935	COG5001	Diguanylate cyclase
VAB027_RS11940	COG1032	radical SAM domain protein
VAB027_RS11945	COG1280	lysine exporter protein (LysE YggA)
VAB027_RS11955	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
VAB027_RS11960	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VAB027_RS11965	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VAB027_RS11970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VAB027_RS11975	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VAB027_RS11980	COG0745	RESPONSE REGULATOR receiver
VAB027_RS11990	COG1609	Transcriptional regulator
VAB027_RS11995	COG3070	regulator of competence-specific genes
VAB027_RS12015	COG0297	glycogen (starch) synthase activity
VAB027_RS12020	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VAB027_RS12025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VAB027_RS12045	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VAB027_RS12050	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
VAB027_RS12055	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VAB027_RS12060	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VAB027_RS12065	COG1960	acyl-CoA dehydrogenase activity
VAB027_RS12085	COG1012	belongs to the aldehyde dehydrogenase family
VAB027_RS12090	COG1309	transcriptional regulator
VAB027_RS12100	COG2995	paraquat-inducible protein a
VAB027_RS12105	COG3008	intermembrane lipid transfer
VAB027_RS12105	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VAB027_RS12115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VAB027_RS12130	COG0582	viral genome integration into host DNA
VAB027_RS12210	COG4790	Type iii secretion
VAB027_RS12220	COG3710	Transcriptional regulator
VAB027_RS12250	COG4792	protein secretion
VAB027_RS12255	COG4789	Type iii secretion
VAB027_RS12360	COG3064	Membrane
VAB027_RS12370	COG0596	Alpha beta hydrolase
VAB027_RS12390	COG5492	domain, Protein
VAB027_RS12390	COG4932	domain protein
VAB027_RS12400	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VAB027_RS12405	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VAB027_RS12410	COG1737	Transcriptional regulator
VAB027_RS12415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VAB027_RS12420	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VAB027_RS12425	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VAB027_RS12430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VAB027_RS12445	COG1940	carbohydrate kinase activity
VAB027_RS12450	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VAB027_RS12455	COG4409	exo-alpha-(2->6)-sialidase activity
VAB027_RS12495	COG5001	Diguanylate cyclase
VAB027_RS12505	COG0415	Belongs to the DNA photolyase family
VAB027_RS12515	COG4628	conserved protein (DUF2132)
VAB027_RS12520	COG3284	Transcriptional regulator
VAB027_RS12525	COG1012	belongs to the aldehyde dehydrogenase family
VAB027_RS12535	COG0784	Response regulator, receiver
VAB027_RS12535	COG5002	protein histidine kinase activity
VAB027_RS12545	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VAB027_RS12555	COG2885	chlorophyll binding
VAB027_RS12560	COG0823	Involved in the tonB-independent uptake of proteins
VAB027_RS12575	COG0811	peptide transport
VAB027_RS12580	COG0824	Thioesterase
VAB027_RS12585	COG3790	cyd operon protein YbgE
VAB027_RS12590	COG4890	Cyd operon protein YbgT
VAB027_RS12595	COG1294	oxidase, subunit
VAB027_RS12600	COG1271	oxidase subunit
VAB027_RS12610	COG0632	four-way junction helicase activity
VAB027_RS12615	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VAB027_RS12620	COG0215	cysteine-tRNA ligase activity
VAB027_RS12625	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VAB027_RS12630	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VAB027_RS12635	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VAB027_RS12640	COG3012	SEC-C Motif Domain Protein
VAB027_RS12645	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VAB027_RS12650	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VAB027_RS12655	COG1199	ATP-dependent helicase activity
VAB027_RS12660	COG0730	response to heat
VAB027_RS12665	COG3923	Primosomal replication protein n
VAB027_RS12675	COG0840	transmembrane signaling receptor activity
VAB027_RS12680	COG0708	Exodeoxyribonuclease III
VAB027_RS12685	COG4160	amino acid transport
VAB027_RS12720	COG0840	transmembrane signaling receptor activity
VAB027_RS12725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VAB027_RS12735	COG3013	Belongs to the UPF0304 family
VAB027_RS12740	COG2766	serine protein kinase
VAB027_RS12750	COG2719	SpoVR family
VAB027_RS12755	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VAB027_RS12760	COG2835	tetraacyldisaccharide 4'-kinase activity
VAB027_RS12765	COG1663	tetraacyldisaccharide 4'-kinase activity
VAB027_RS12770	COG1132	(ABC) transporter
VAB027_RS12775	COG2333	competence protein COMEC
VAB027_RS12775	COG0658	competence protein
VAB027_RS12785	COG4591	ABC-type transport system involved in lipoprotein release permease component
VAB027_RS12790	COG1136	(ABC) transporter
VAB027_RS12795	COG4591	ABC-type transport system involved in lipoprotein release permease component
VAB027_RS12805	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VAB027_RS12825	COG1252	NADH dehydrogenase
VAB027_RS12855	COG0537	adenosine 5'-monophosphoramidase activity
VAB027_RS12870	COG2186	Transcriptional regulator
VAB027_RS12875	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VAB027_RS12880	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VAB027_RS12885	COG1674	ftsk spoiiie
VAB027_RS12895	COG0686	Belongs to the AlaDH PNT family
VAB027_RS12905	COG0583	DNA-binding transcription factor activity
VAB027_RS12925	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VAB027_RS12930	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VAB027_RS12935	COG0776	regulation of translation
VAB027_RS12940	COG0539	negative regulation of cytoplasmic translation
VAB027_RS12945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VAB027_RS12950	COG1555	photosystem II stabilization
VAB027_RS12955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VAB027_RS12960	COG0776	regulation of translation
VAB027_RS12965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VAB027_RS12970	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VAB027_RS12980	COG0544	peptidyl-prolyl cis-trans isomerase activity
VAB027_RS12990	COG4191	Histidine kinase
VAB027_RS13000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VAB027_RS13005	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VAB027_RS13010	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VAB027_RS13015	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VAB027_RS13030	COG5001	Diguanylate cyclase
VAB027_RS13030	COG3300	MHYT domain
VAB027_RS13040	COG4589	Belongs to the CDS family
VAB027_RS13075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VAB027_RS13085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VAB027_RS13100	COG0243	molybdopterin cofactor binding
VAB027_RS13105	COG3005	denitrification pathway
VAB027_RS13110	COG3469	chitinase activity
VAB027_RS13110	COG3325	Belongs to the glycosyl hydrolase 18 family
VAB027_RS13115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VAB027_RS13125	COG2951	lytic endotransglycosylase activity
VAB027_RS13130	COG3100	YcgL domain-containing protein
VAB027_RS13135	COG0850	regulation of cytokinetic process
VAB027_RS13140	COG2894	cell division
VAB027_RS13145	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VAB027_RS13150	COG3015	lipoprotein NlpE involved in copper resistance
VAB027_RS13175	COG3135	benzoate transporter
VAB027_RS13195	COG0596	Alpha beta hydrolase
VAB027_RS13200	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VAB027_RS13205	COG1169	isochorismate synthase
VAB027_RS13210	COG0436	Aminotransferase
VAB027_RS13215	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VAB027_RS13220	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VAB027_RS13240	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VAB027_RS13245	COG0318	PFAM AMP-dependent synthetase and ligase
VAB027_RS13250	COG0596	Alpha beta hydrolase
VAB027_RS13265	COG1214	PFAM Peptidase M22, glycoprotease
VAB027_RS13270	COG1199	ATP-dependent helicase activity
VAB027_RS13280	COG0788	formyltetrahydrofolate deformylase activity
VAB027_RS13285	COG0446	pyridine nucleotide-disulphide oxidoreductase
VAB027_RS13285	COG1902	pentaerythritol trinitrate reductase activity
VAB027_RS13290	COG0616	signal peptide processing
VAB027_RS13295	COG0252	asparaginase activity
VAB027_RS13300	COG3139	Protein of unknown function (DUF1315)
VAB027_RS13310	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VAB027_RS13315	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VAB027_RS13320	COG0676	glucose-6-phosphate 1-epimerase activity
VAB027_RS13330	COG2226	methyltransferase
VAB027_RS13345	COG0784	Response regulator, receiver
VAB027_RS13345	COG0835	chemotaxis
VAB027_RS13350	COG1940	carbohydrate kinase activity
VAB027_RS13360	COG4667	esterase of the alpha-beta hydrolase superfamily
VAB027_RS13375	COG0733	neurotransmitter:sodium symporter activity
VAB027_RS13380	COG3385	transposase activity
VAB027_RS13385	COG1263	PTS System
VAB027_RS13385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VAB027_RS13390	COG0084	hydrolase, TatD family'
VAB027_RS13400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VAB027_RS13405	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VAB027_RS13410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VAB027_RS13415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VAB027_RS13420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VAB027_RS13425	COG1028	Short-chain dehydrogenase reductase Sdr
VAB027_RS13435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VAB027_RS13440	COG0416	fatty acid biosynthetic process
VAB027_RS13445	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VAB027_RS13450	COG1399	metal-binding, possibly nucleic acid-binding protein
VAB027_RS13455	COG0424	maF-like protein
VAB027_RS13460	COG0564	pseudouridine synthase activity
VAB027_RS13475	COG1530	ribonuclease E activity
VAB027_RS13480	COG0659	secondary active sulfate transmembrane transporter activity
VAB027_RS13490	COG1454	alcohol dehydrogenase
VAB027_RS13490	COG1012	belongs to the aldehyde dehydrogenase family
VAB027_RS13495	COG2095	MarC family integral membrane protein
VAB027_RS13500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VAB027_RS13505	COG1757	Na H antiporter
VAB027_RS13515	COG3081	Nucleoid-associated protein
VAB027_RS13520	COG3082	Protein of unknown function (DUF1414)
VAB027_RS13525	COG3083	sulfuric ester hydrolase activity
VAB027_RS13540	COG0123	including yeast histone deacetylase and acetoin utilization protein
VAB027_RS13545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VAB027_RS13550	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VAB027_RS13570	COG2853	Lipoprotein
VAB027_RS13580	COG3088	subunit of a heme lyase
VAB027_RS13580	COG4235	cytochrome complex assembly
VAB027_RS13585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VAB027_RS13590	COG1138	Cytochrome C-type biogenesis protein
VAB027_RS13595	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VAB027_RS13605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VAB027_RS13610	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VAB027_RS13615	COG4133	protoheme IX ABC transporter activity
VAB027_RS13625	COG0835	chemotaxis
VAB027_RS13635	COG1192	Involved in chromosome partitioning
VAB027_RS13640	COG2201	protein-glutamate methylesterase activity
VAB027_RS13645	COG2198	Histidine kinase
VAB027_RS13645	COG0643	Histidine kinase
VAB027_RS13645	COG0784	Response regulator, receiver
VAB027_RS13650	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VAB027_RS13680	COG2062	phosphohistidine phosphatase, SixA
VAB027_RS13685	COG1025	Belongs to the peptidase M16 family
VAB027_RS13695	COG0018	arginyl-trna synthetase
VAB027_RS13715	COG1918	ferrous iron import across plasma membrane
VAB027_RS13725	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VAB027_RS13730	COG1121	(ABC) transporter
VAB027_RS13735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VAB027_RS13745	COG0045	succinate-CoA ligase (ADP-forming) activity
VAB027_RS13750	COG0508	dehydrogenase complex catalyzes the overall conversion of
VAB027_RS13755	COG0567	Dehydrogenase, E1 component
VAB027_RS13765	COG1053	succinate dehydrogenase
VAB027_RS13770	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VAB027_RS13775	COG2009	succinate dehydrogenase
VAB027_RS13780	COG0372	Belongs to the citrate synthase family
VAB027_RS13785	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VAB027_RS13795	COG0033	Phosphoglucomutase
VAB027_RS13800	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VAB027_RS13805	COG0596	Alpha beta hydrolase
VAB027_RS13830	COG0583	DNA-binding transcription factor activity
VAB027_RS13840	COG0735	belongs to the Fur family
VAB027_RS13845	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VAB027_RS13850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VAB027_RS13855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VAB027_RS13860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VAB027_RS13860	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VAB027_RS13865	COG0431	NADPH-dependent FMN reductase
VAB027_RS13875	COG3101	peptidyl-lysine hydroxylation
VAB027_RS13880	COG2860	membrane
VAB027_RS13885	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VAB027_RS13895	COG2890	protein-(glutamine-N5) methyltransferase activity
VAB027_RS13910	COG1684	flagellar biosynthetic protein fliR
VAB027_RS13915	COG1987	bacterial-type flagellum assembly
VAB027_RS13940	COG1580	Controls the rotational direction of flagella during chemotaxis
VAB027_RS13960	COG1317	bacterial-type flagellum organization
VAB027_RS13965	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VAB027_RS13975	COG1677	Flagellar hook-basal body complex protein FliE
VAB027_RS13995	COG1516	flagellar protein fliS
VAB027_RS14005	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VAB027_RS14010	COG1334	flagellar protein FlaG
VAB027_RS14015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VAB027_RS14020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VAB027_RS14025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VAB027_RS14030	COG2837	iron assimilation
VAB027_RS14050	COG1393	Belongs to the ArsC family
VAB027_RS14060	COG1876	peptidase activity
VAB027_RS14070	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VAB027_RS14085	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VAB027_RS14105	COG4783	chaperone-mediated protein folding
VAB027_RS14110	COG1393	Belongs to the ArsC family
VAB027_RS14135	COG2233	PERMEase
VAB027_RS14140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VAB027_RS14145	COG0737	Belongs to the 5'-nucleotidase family
VAB027_RS14150	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VAB027_RS14155	COG2912	Transglutaminase-like superfamily
VAB027_RS14165	COG2890	protein-(glutamine-N5) methyltransferase activity
VAB027_RS14170	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VAB027_RS14175	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VAB027_RS14180	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VAB027_RS14185	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VAB027_RS14190	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VAB027_RS14195	COG0193	aminoacyl-tRNA hydrolase activity
VAB027_RS14200	COG0012	GTP binding
VAB027_RS14285	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VAB027_RS14290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VAB027_RS14310	COG3951	Flagellar rod assembly protein muramidase FlgJ
VAB027_RS14310	COG1705	Flagellar rod assembly protein muramidase FlgJ
VAB027_RS14315	COG1706	bacterial-type flagellum-dependent cell motility
VAB027_RS14320	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VAB027_RS14330	COG4787	bacterial-type flagellum-dependent cell motility
VAB027_RS14335	COG1749	Flagellar hook protein flgE
VAB027_RS14350	COG1815	bacterial-type flagellum-dependent cell motility
VAB027_RS14355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VAB027_RS14360	COG0835	chemotaxis
VAB027_RS14360	COG0784	Response regulator, receiver
VAB027_RS14395	COG2226	methyltransferase
VAB027_RS14395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VAB027_RS14395	COG3433	isochorismatase activity
VAB027_RS14400	COG2375	cellular response to nickel ion
VAB027_RS14405	COG4774	siderophore transport
VAB027_RS14405	COG1629	transport
VAB027_RS14420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VAB027_RS14425	COG2217	Heavy metal translocating P-type atpase
VAB027_RS14425	COG2608	mercury ion transmembrane transporter activity
VAB027_RS14455	COG2840	Smr protein MutS2
VAB027_RS14460	COG1187	pseudouridine synthase activity
VAB027_RS14475	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VAB027_RS14480	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VAB027_RS14485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VAB027_RS14490	COG0121	glutamine amidotransferase
VAB027_RS14495	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VAB027_RS14500	COG1960	acyl-CoA dehydrogenase activity
VAB027_RS14515	COG0328	RNA-DNA hybrid ribonuclease activity
VAB027_RS14520	COG2226	methyltransferase
VAB027_RS14525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VAB027_RS14530	COG1388	LysM domain
VAB027_RS14530	COG0741	lytic transglycosylase activity
VAB027_RS14535	COG3021	interspecies interaction between organisms
VAB027_RS14540	COG0347	Belongs to the P(II) protein family
VAB027_RS14545	COG3479	Phenolic acid decarboxylase
VAB027_RS14555	COG0037	tRNA processing
VAB027_RS14560	COG0825	malonyl-CoA metabolic process
VAB027_RS14565	COG0587	DNA-directed DNA polymerase activity
VAB027_RS14570	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VAB027_RS14575	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VAB027_RS14580	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VAB027_RS14585	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VAB027_RS14590	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VAB027_RS14595	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VAB027_RS14605	COG0750	zinc metalloprotease
VAB027_RS14610	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VAB027_RS14615	COG0575	Belongs to the CDS family
VAB027_RS14620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VAB027_RS14625	COG0233	cytoplasmic translational termination
VAB027_RS14630	COG0528	UMP kinase activity
VAB027_RS14635	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VAB027_RS14640	COG0052	Belongs to the universal ribosomal protein uS2 family
VAB027_RS14645	COG0024	Methionine aminopeptidase
VAB027_RS14650	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VAB027_RS14660	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VAB027_RS14665	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VAB027_RS14670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VAB027_RS14675	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VAB027_RS14690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VAB027_RS14690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VAB027_RS14695	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VAB027_RS14700	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VAB027_RS14705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VAB027_RS14715	COG1073	alpha beta
VAB027_RS14720	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VAB027_RS14725	COG2252	PERMEase
VAB027_RS14730	COG2195	Cleaves the N-terminal amino acid of tripeptides
VAB027_RS14735	COG4067	protein conserved in archaea
VAB027_RS14735	COG0189	ligase activity
VAB027_RS14740	COG0189	ligase activity
VAB027_RS14750	COG0733	neurotransmitter:sodium symporter activity
VAB027_RS14755	COG3706	GGDEF domain
VAB027_RS14775	COG1477	protein flavinylation
VAB027_RS14780	COG2871	sodium ion transport
VAB027_RS14785	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VAB027_RS14790	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VAB027_RS14795	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VAB027_RS14800	COG1805	sodium ion transport
VAB027_RS14805	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VAB027_RS14810	COG0271	Belongs to the BolA IbaG family
VAB027_RS14815	COG2813	Specifically methylates the guanine in position
VAB027_RS14825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VAB027_RS14830	COG2211	Major facilitator Superfamily
VAB027_RS14840	COG1595	DNA-templated transcription, initiation
VAB027_RS14850	COG3248	Nucleoside-binding outer membrane protein
VAB027_RS14855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VAB027_RS14860	COG0693	protein deglycase activity
VAB027_RS14865	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VAB027_RS14870	COG2166	iron-sulfur cluster assembly
VAB027_RS14875	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VAB027_RS14880	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VAB027_RS14890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VAB027_RS14890	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VAB027_RS14905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VAB027_RS14910	COG1074	ATP-dependent DNA helicase activity
VAB027_RS14915	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VAB027_RS14930	COG3141	response to X-ray
VAB027_RS14935	COG2171	N-acyltransferase activity
VAB027_RS14945	COG0456	acetyltransferase
VAB027_RS14950	COG0189	ligase activity
VAB027_RS14950	COG0569	domain protein
VAB027_RS14965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VAB027_RS14970	COG1609	Transcriptional regulator
VAB027_RS14975	COG3250	beta-galactosidase activity
VAB027_RS14990	COG1022	Amp-dependent synthetase and ligase
VAB027_RS14995	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VAB027_RS15000	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VAB027_RS15010	COG0560	Phosphoserine phosphatase
VAB027_RS15020	COG0813	purine-nucleoside phosphorylase activity
VAB027_RS15025	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VAB027_RS15030	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VAB027_RS15035	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VAB027_RS15045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VAB027_RS15050	COG0084	hydrolase, TatD family'
VAB027_RS15055	COG3022	response to hydroperoxide
VAB027_RS15060	COG1115	amino acid carrier protein
VAB027_RS15075	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VAB027_RS15080	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VAB027_RS15085	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VAB027_RS15090	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VAB027_RS15095	COG0083	homoserine kinase activity
VAB027_RS15110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VAB027_RS15120	COG0745	RESPONSE REGULATOR receiver
VAB027_RS15125	COG5002	protein histidine kinase activity
VAB027_RS15125	COG2198	Histidine kinase
VAB027_RS15125	COG0784	Response regulator, receiver
VAB027_RS15130	COG5001	Diguanylate cyclase
VAB027_RS15130	COG4251	negative regulation of phosphorylation
VAB027_RS15130	COG3706	GGDEF domain
VAB027_RS15130	COG2203	Gaf domain
VAB027_RS15135	COG1242	4 iron, 4 sulfur cluster binding
VAB027_RS15150	COG0069	glutamate synthase activity
VAB027_RS15150	COG0067	glutamate synthase
VAB027_RS15150	COG0070	glutamate synthase
VAB027_RS15155	COG0493	'glutamate synthase
VAB027_RS15165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VAB027_RS15175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VAB027_RS15180	COG2860	membrane
VAB027_RS15185	COG0583	DNA-binding transcription factor activity
VAB027_RS15190	COG0730	response to heat
VAB027_RS15210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VAB027_RS15215	COG0505	Belongs to the CarA family
VAB027_RS15225	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VAB027_RS15230	COG0494	nUDIX hydrolase
VAB027_RS15240	COG0653	protein targeting
VAB027_RS15250	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VAB027_RS15255	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VAB027_RS15260	COG0849	cell division
VAB027_RS15265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VAB027_RS15270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VAB027_RS15280	COG0772	Belongs to the SEDS family
VAB027_RS15285	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VAB027_RS15295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VAB027_RS15300	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VAB027_RS15305	COG0768	penicillin binding
VAB027_RS15310	COG3116	cell division
VAB027_RS15320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VAB027_RS15325	COG0508	dehydrogenase complex catalyzes the overall conversion of
VAB027_RS15330	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VAB027_RS15335	COG2186	Transcriptional regulator
VAB027_RS15340	COG0737	Belongs to the 5'-nucleotidase family
VAB027_RS15345	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VAB027_RS15350	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VAB027_RS15355	COG4974	Belongs to the 'phage' integrase family
VAB027_RS15360	COG0716	FMN binding
VAB027_RS15385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VAB027_RS15390	COG1459	type II secretion system
VAB027_RS15400	COG0237	dephospho-CoA kinase activity
VAB027_RS15405	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VAB027_RS15415	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VAB027_RS15420	COG0187	DNA topoisomerase II activity
VAB027_RS15425	COG3150	esterase
VAB027_RS15435	COG3151	Protein conserved in bacteria
VAB027_RS15440	COG0494	nUDIX hydrolase
VAB027_RS15445	COG1538	Outer membrane efflux protein
VAB027_RS15450	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
VAB027_RS15450	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
VAB027_RS15455	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VAB027_RS15460	COG0840	transmembrane signaling receptor activity
VAB027_RS15465	COG3025	triphosphatase activity
VAB027_RS15470	COG1392	Phosphate transport regulator
VAB027_RS15475	COG0306	phosphate transporter
VAB027_RS15480	COG4991	sh3 domain protein
VAB027_RS15490	COG3267	Type II secretory pathway component ExeA
VAB027_RS15490	COG3409	Peptidoglycan-binding domain 1 protein
VAB027_RS15500	COG0148	phosphopyruvate hydratase activity
VAB027_RS15505	COG0504	CTP synthase activity
VAB027_RS15510	COG3956	TIGRFAM MazG family protein
VAB027_RS15515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VAB027_RS15545	COG0736	holo-[acyl-carrier-protein] synthase activity
VAB027_RS15550	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VAB027_RS15555	COG1381	Involved in DNA repair and RecF pathway recombination
VAB027_RS15560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VAB027_RS15565	COG0571	ribonuclease III activity
VAB027_RS15575	COG0481	GTPase activity
VAB027_RS15580	COG3086	response to oxidative stress
VAB027_RS15585	COG3026	antisigma factor binding
VAB027_RS15595	COG1595	DNA-templated transcription, initiation
VAB027_RS15605	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VAB027_RS15615	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VAB027_RS15630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VAB027_RS15635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VAB027_RS15640	COG3079	Belongs to the UPF0149 family
VAB027_RS15645	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VAB027_RS15650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VAB027_RS15655	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VAB027_RS15660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VAB027_RS15665	COG0440	acetolactate synthase activity
VAB027_RS15670	COG0028	Belongs to the TPP enzyme family
VAB027_RS15675	COG1022	Amp-dependent synthetase and ligase
VAB027_RS15680	COG0583	DNA-binding transcription factor activity
VAB027_RS15700	COG0473	3-isopropylmalate dehydrogenase activity
VAB027_RS15705	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VAB027_RS15710	COG0066	3-isopropylmalate dehydratase activity
VAB027_RS15755	COG0542	response to heat
VAB027_RS15765	COG0564	pseudouridine synthase activity
VAB027_RS15770	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VAB027_RS15775	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VAB027_RS15780	COG1605	Chorismate mutase
VAB027_RS15780	COG0077	Prephenate dehydratase
VAB027_RS15785	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VAB027_RS15790	COG5001	Diguanylate cyclase
VAB027_RS15800	COG3941	tape measure
VAB027_RS15840	COG0488	(ABC) transporter
VAB027_RS15880	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VAB027_RS15890	COG0488	(ABC) transporter
VAB027_RS15900	COG1605	Chorismate mutase
VAB027_RS15900	COG0287	Prephenate dehydrogenase
VAB027_RS15905	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VAB027_RS15910	COG3275	phosphorelay sensor kinase activity
VAB027_RS15915	COG3279	Response regulator of the LytR AlgR family
VAB027_RS15925	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VAB027_RS15930	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VAB027_RS15945	COG1966	Carbon starvation protein
VAB027_RS15950	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VAB027_RS15955	COG1047	Peptidyl-prolyl cis-trans
VAB027_RS15960	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VAB027_RS15970	COG0196	riboflavin kinase activity
VAB027_RS15975	COG0728	peptidoglycan biosynthetic process
VAB027_RS15980	COG0268	Binds directly to 16S ribosomal RNA
VAB027_RS15985	COG0640	Transcriptional regulator
VAB027_RS15990	COG0583	DNA-binding transcription factor activity
VAB027_RS15995	COG1283	sodium-dependent phosphate transmembrane transporter activity
VAB027_RS16005	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VAB027_RS16010	COG0730	response to heat
VAB027_RS16015	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
VAB027_RS16020	COG0494	nUDIX hydrolase
VAB027_RS16035	COG0667	Aldo Keto reductase
VAB027_RS16045	COG2204	response regulator
VAB027_RS16050	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VAB027_RS16055	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VAB027_RS16095	COG3153	acetyltransferase
VAB027_RS16100	COG3154	lipid carrier protein
VAB027_RS16110	COG0826	peptidase U32
VAB027_RS16115	COG0826	peptidase U32
VAB027_RS16140	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VAB027_RS16150	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VAB027_RS16155	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VAB027_RS16160	COG0195	Participates in both transcription termination and antitermination
VAB027_RS16165	COG0779	Required for maturation of 30S ribosomal subunits
VAB027_RS16180	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VAB027_RS16190	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VAB027_RS16195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VAB027_RS16200	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VAB027_RS16205	COG1534	Rna-binding protein
VAB027_RS16210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VAB027_RS16220	COG2027	D-alanyl-D-alanine carboxypeptidase
VAB027_RS16225	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VAB027_RS16230	COG0739	heme binding
VAB027_RS16235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VAB027_RS16245	COG0316	Belongs to the HesB IscA family
VAB027_RS16250	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VAB027_RS16260	COG0628	permease
VAB027_RS16265	COG2813	Specifically methylates the guanine in position
VAB027_RS16280	COG0747	negative chemotaxis
VAB027_RS16285	COG0601	transmembrane transport
VAB027_RS16290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VAB027_RS16295	COG0444	Belongs to the ABC transporter superfamily
VAB027_RS16300	COG4608	Belongs to the ABC transporter superfamily
VAB027_RS16310	COG2971	BadF BadG BcrA BcrD
VAB027_RS16330	COG3842	ATPase activity
VAB027_RS16340	COG1840	ABC-type Fe3 transport system, periplasmic component
VAB027_RS16345	COG0004	ammonium transporteR
VAB027_RS16350	COG0347	Belongs to the P(II) protein family
VAB027_RS16355	COG3112	Uncharacterised protein family (UPF0231)
VAB027_RS16360	COG1049	propionate catabolic process, 2-methylcitrate cycle
VAB027_RS16370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VAB027_RS16375	COG1643	Atp-dependent helicase
VAB027_RS16385	COG1489	DNA binding
VAB027_RS16395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VAB027_RS16405	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VAB027_RS16410	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VAB027_RS16415	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VAB027_RS16420	COG0842	Transport permease protein
VAB027_RS16425	COG1131	(ABC) transporter
VAB027_RS16430	COG0659	secondary active sulfate transmembrane transporter activity
VAB027_RS16435	COG0288	reversible hydration of carbon dioxide
VAB027_RS16450	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VAB027_RS16455	COG3107	peptidoglycan biosynthetic process
VAB027_RS16460	COG0792	nuclease activity
VAB027_RS16465	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VAB027_RS16470	COG2823	Periplasmic or secreted lipoprotein
VAB027_RS16475	COG2969	positive regulation of protein catabolic process
VAB027_RS16480	COG0625	glutathione transferase activity
VAB027_RS16485	COG2857	Cytochrome c1
VAB027_RS16490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VAB027_RS16495	COG0723	plastoquinol--plastocyanin reductase activity
VAB027_RS16500	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VAB027_RS16505	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VAB027_RS16515	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VAB027_RS16525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VAB027_RS16530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VAB027_RS16535	COG0335	large ribosomal subunit rRNA binding
VAB027_RS16540	COG0336	Belongs to the RNA methyltransferase TrmD family
VAB027_RS16545	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VAB027_RS16550	COG0228	four-way junction DNA binding
VAB027_RS16555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VAB027_RS16560	COG4137	Cytochrome C assembly protein
VAB027_RS16565	COG4536	flavin adenine dinucleotide binding
VAB027_RS16570	COG1854	S-ribosylhomocysteine lyase activity
VAB027_RS16575	COG2918	glutathione biosynthetic process
VAB027_RS16580	COG0612	Peptidase, M16
VAB027_RS16585	COG1238	metal cluster binding
VAB027_RS16595	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VAB027_RS16600	COG0511	ligase activity, forming carbon-carbon bonds
VAB027_RS16600	COG5016	pyruvate
VAB027_RS16605	COG3630	sodium ion export across plasma membrane
VAB027_RS16650	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VAB027_RS16655	COG0527	aspartate kinase activity
VAB027_RS16660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VAB027_RS16665	COG2137	regulation of response to DNA damage stimulus
VAB027_RS16670	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VAB027_RS16680	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VAB027_RS16685	COG4208	sulfate ABC transporter
VAB027_RS16710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VAB027_RS16720	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VAB027_RS16725	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VAB027_RS16730	COG0585	pseudouridine synthase activity
VAB027_RS16735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VAB027_RS16740	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VAB027_RS16745	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VAB027_RS16750	COG1968	undecaprenyl-diphosphatase activity
VAB027_RS16755	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VAB027_RS16760	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VAB027_RS16770	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VAB027_RS16780	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VAB027_RS16785	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VAB027_RS16790	COG1610	YqeY-like protein
VAB027_RS16795	COG0358	DNA primase activity
VAB027_RS16815	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VAB027_RS16820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VAB027_RS16825	COG1349	DNA-binding transcription factor activity
VAB027_RS16855	COG1279	arginine transmembrane transporter activity
VAB027_RS16860	COG0668	transmembrane transport
VAB027_RS16870	COG0191	fructose-bisphosphate aldolase activity
VAB027_RS16875	COG0126	phosphoglycerate kinase activity
VAB027_RS16880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VAB027_RS16885	COG4771	TonB-dependent receptor
VAB027_RS16890	COG0583	DNA-binding transcription factor activity
VAB027_RS16895	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VAB027_RS16905	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VAB027_RS16910	COG3091	SprT-like family
VAB027_RS16915	COG2356	endonuclease I
VAB027_RS16920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VAB027_RS16925	COG0189	ligase activity
VAB027_RS16930	COG1678	Uncharacterized ACR, COG1678
VAB027_RS16935	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VAB027_RS16940	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VAB027_RS16960	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VAB027_RS16965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VAB027_RS16970	COG0762	integral membrane protein
VAB027_RS16975	COG1872	DUF167
VAB027_RS16985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VAB027_RS16990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VAB027_RS16995	COG2066	Belongs to the glutaminase family
VAB027_RS17000	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VAB027_RS17005	COG1194	a g-specific adenine glycosylase
VAB027_RS17010	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VAB027_RS17015	COG0741	lytic transglycosylase activity
VAB027_RS17070	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VAB027_RS17075	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VAB027_RS17080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VAB027_RS17085	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VAB027_RS17090	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VAB027_RS17095	COG2967	ApaG domain
VAB027_RS17100	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VAB027_RS17110	COG3610	response to peptide
VAB027_RS17115	COG2966	Psort location CytoplasmicMembrane, score
VAB027_RS17120	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VAB027_RS17125	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VAB027_RS17130	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VAB027_RS17135	COG0142	geranyltranstransferase activity
VAB027_RS17140	COG0531	amino acid
VAB027_RS17145	COG0039	L-malate dehydrogenase activity
VAB027_RS17150	COG1438	arginine binding
VAB027_RS17155	COG2358	TRAP transporter, solute receptor (TAXI family
VAB027_RS17165	COG0589	response to stress
VAB027_RS17185	COG2235	arginine
VAB027_RS17190	COG0312	modulator of DNA gyrase
VAB027_RS17195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VAB027_RS17200	COG3164	Protein of unknown function
VAB027_RS17210	COG0424	maF-like protein
VAB027_RS17215	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VAB027_RS17220	COG1792	Involved in formation and maintenance of cell shape
VAB027_RS17225	COG1077	Cell shape determining protein MreB Mrl
VAB027_RS17255	COG2165	general secretion pathway protein
VAB027_RS17260	COG2165	general secretion pathway protein
VAB027_RS17275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VAB027_RS17285	COG3267	Type II secretory pathway component ExeA
VAB027_RS17285	COG3409	Peptidoglycan-binding domain 1 protein
VAB027_RS17310	COG2200	EAL domain
VAB027_RS17310	COG2199	diguanylate cyclase activity
VAB027_RS17315	COG0629	single-stranded DNA binding
VAB027_RS17330	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VAB027_RS17340	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VAB027_RS17345	COG0527	aspartate kinase activity
VAB027_RS17350	COG0646	methionine synthase
VAB027_RS17350	COG1410	methionine synthase
VAB027_RS17390	COG0175	sulfate reduction
VAB027_RS17400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VAB027_RS17425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VAB027_RS17430	COG0735	belongs to the Fur family
VAB027_RS17445	COG0166	Belongs to the GPI family
VAB027_RS17450	COG0432	Pfam Uncharacterised protein family UPF0047
VAB027_RS17455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VAB027_RS17470	COG0359	binds to the 23S rRNA
VAB027_RS17475	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VAB027_RS17480	COG2965	DNA replication, synthesis of RNA primer
VAB027_RS17485	COG0360	Binds together with S18 to 16S ribosomal RNA
VAB027_RS17495	COG2906	2 iron, 2 sulfur cluster binding
VAB027_RS17500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VAB027_RS17505	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VAB027_RS17510	COG0049	tRNA binding
VAB027_RS17525	COG2923	Belongs to the DsrF TusC family
VAB027_RS17530	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VAB027_RS17535	COG2964	Protein conserved in bacteria
VAB027_RS17540	COG0545	Peptidyl-prolyl cis-trans isomerase
VAB027_RS17550	COG2900	Belongs to the SlyX family
VAB027_RS17555	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VAB027_RS17560	COG0330	HflC and HflK could
VAB027_RS17565	COG0330	HflC and HflK could
VAB027_RS17570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VAB027_RS17575	COG1923	regulation of RNA biosynthetic process
VAB027_RS17580	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VAB027_RS17585	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VAB027_RS17595	COG0802	atpase or kinase
VAB027_RS17600	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VAB027_RS17650	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VAB027_RS17655	COG1162	GTPase activity
VAB027_RS17660	COG0688	phosphatidylethanolamine metabolic process
VAB027_RS17665	COG0471	metal ion transport
VAB027_RS17675	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VAB027_RS17680	COG4942	peptidase
VAB027_RS17695	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VAB027_RS17700	COG2816	NAD+ diphosphatase activity
VAB027_RS17705	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VAB027_RS17710	COG3385	transposase activity
VAB027_RS17715	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VAB027_RS17720	COG0085	RNA polymerase activity
VAB027_RS17725	COG0222	ribosome binding
VAB027_RS17730	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VAB027_RS17740	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VAB027_RS17745	COG0250	Participates in transcription elongation, termination and antitermination
VAB027_RS17750	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VAB027_RS17755	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VAB027_RS17780	COG1072	(Pantothenic acid kinase))
VAB027_RS17790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VAB027_RS17805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VAB027_RS17845	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VAB027_RS17860	COG3118	belongs to the thioredoxin family
VAB027_RS17865	COG0513	Belongs to the DEAD box helicase family
VAB027_RS17870	COG0248	Ppx GppA phosphatase
VAB027_RS17875	COG2205	protein histidine kinase activity
VAB027_RS17875	COG0784	Response regulator, receiver
VAB027_RS17880	COG2814	Major facilitator Superfamily
VAB027_RS17900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VAB027_RS17905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VAB027_RS17910	COG0511	ligase activity, forming carbon-carbon bonds
VAB027_RS17915	COG0439	Biotin carboxylase
VAB027_RS17920	COG2264	protein methyltransferase activity
VAB027_RS17925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VAB027_RS17930	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VAB027_RS17940	COG1609	Transcriptional regulator
VAB027_RS17945	COG0129	dihydroxy-acid dehydratase activity
VAB027_RS17950	COG3265	gluconokinase activity
VAB027_RS17960	COG0800	Aldolase
VAB027_RS17975	COG0840	transmembrane signaling receptor activity
VAB027_RS17980	COG1982	Orn Lys Arg decarboxylase major
VAB027_RS17985	COG0531	amino acid
VAB027_RS17990	COG3710	Transcriptional regulator
VAB027_RS17995	COG0789	Transcriptional regulator
VAB027_RS18010	COG0151	Belongs to the GarS family
VAB027_RS18020	COG0776	regulation of translation
VAB027_RS18030	COG1253	flavin adenine dinucleotide binding
VAB027_RS18065	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VAB027_RS18070	COG3068	Protein conserved in bacteria
VAB027_RS18080	COG1573	uracil-dna glycosylase
VAB027_RS18085	COG0668	transmembrane transport
VAB027_RS18090	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VAB027_RS18100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VAB027_RS18150	COG1028	Short-chain dehydrogenase reductase Sdr
VAB027_RS18155	COG1083	cytidylyl-transferase
VAB027_RS18160	COG0673	inositol 2-dehydrogenase activity
VAB027_RS18175	COG2089	acid synthase
VAB027_RS18180	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VAB027_RS18185	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VAB027_RS18195	COG5433	transposase activity
VAB027_RS18205	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
VAB027_RS18210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VAB027_RS18220	COG0110	maltose O-acetyltransferase activity
VAB027_RS18235	COG0859	PFAM glycosyl transferase family 9
VAB027_RS18245	COG1519	Transferase
VAB027_RS18275	COG2755	lipolytic protein G-D-S-L family
VAB027_RS18275	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
VAB027_RS18280	COG3642	lipopolysaccharide core region biosynthetic process
VAB027_RS18285	COG0859	PFAM glycosyl transferase family 9
VAB027_RS18290	COG0463	Glycosyl transferase, family 2
VAB027_RS18295	COG0859	PFAM glycosyl transferase family 9
VAB027_RS18300	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VAB027_RS18305	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VAB027_RS18315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VAB027_RS18320	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VAB027_RS18325	COG2003	Belongs to the UPF0758 family
VAB027_RS18335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VAB027_RS18340	COG1309	transcriptional regulator
VAB027_RS18345	COG1560	Kdo2-lipid A biosynthetic process
VAB027_RS18350	COG1560	Kdo2-lipid A biosynthetic process
VAB027_RS18355	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VAB027_RS18360	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VAB027_RS18365	COG1561	YicC-like family, N-terminal region
VAB027_RS18465	COG2862	Uncharacterized protein family, UPF0114
VAB027_RS18470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VAB027_RS18470	COG1263	PTS System
VAB027_RS18475	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VAB027_RS18500	COG1120	ATPase activity
VAB027_RS18505	COG4774	siderophore transport
VAB027_RS18510	COG1132	(ABC) transporter
VAB027_RS18525	COG0514	ATP-dependent DNA helicase (RecQ)
VAB027_RS18530	COG2962	Rard protein
VAB027_RS18535	COG0405	Gamma-glutamyltransferase
VAB027_RS18545	COG1280	lysine exporter protein (LysE YggA)
VAB027_RS18550	COG0210	DNA helicase
VAB027_RS18560	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VAB027_RS18565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VAB027_RS18575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VAB027_RS18580	COG0601	transmembrane transport
VAB027_RS18585	COG0747	negative chemotaxis
VAB027_RS18640	COG1309	transcriptional regulator
VAB027_RS18645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VAB027_RS18650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VAB027_RS18655	COG2960	long-chain fatty acid transporting porin activity
VAB027_RS18660	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VAB027_RS18665	COG0583	DNA-binding transcription factor activity
VAB027_RS18710	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
VAB027_RS18715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VAB027_RS18720	COG1739	Uncharacterized protein family UPF0029
VAB027_RS18725	COG1024	Enoyl-CoA hydratase
VAB027_RS18725	COG1250	3-hydroxyacyl-CoA dehydrogenase
VAB027_RS18730	COG0183	Belongs to the thiolase family
VAB027_RS18735	COG0583	DNA-binding transcription factor activity
VAB027_RS18740	COG2814	Major facilitator Superfamily
VAB027_RS18750	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VAB027_RS18755	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VAB027_RS18760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VAB027_RS18765	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VAB027_RS18770	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VAB027_RS18775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VAB027_RS18785	COG0356	it plays a direct role in the translocation of protons across the membrane
VAB027_RS18790	COG3312	ion transport
VAB027_RS18795	COG1475	DNA binding
VAB027_RS18800	COG1192	Involved in chromosome partitioning
VAB027_RS18805	COG0357	Ribosomal RNA small subunit methyltransferase G
VAB027_RS18810	COG0445	tRNA wobble uridine modification
VAB027_RS18820	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VAB027_RS18835	COG0464	growth
VAB027_RS18950	COG4974	Belongs to the 'phage' integrase family
VAB027_RS18955	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VAB027_RS18960	COG0706	membrane insertase activity
VAB027_RS18970	COG0594	ribonuclease P activity
VAB027_RS18975	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VAB027_RS18980	COG1126	abc transporter atp-binding protein
VAB027_RS19025	COG1401	restriction endodeoxyribonuclease activity