locus-tag	class	description
GPX93_RS00010	COG0583	DNA-binding transcription factor activity
GPX93_RS00015	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GPX93_RS00020	COG2960	long-chain fatty acid transporting porin activity
GPX93_RS00025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPX93_RS00030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPX93_RS00035	COG1309	transcriptional regulator
GPX93_RS00090	COG0747	negative chemotaxis
GPX93_RS00100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPX93_RS00110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPX93_RS00115	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GPX93_RS00125	COG0210	DNA helicase
GPX93_RS00130	COG1280	lysine exporter protein (LysE YggA)
GPX93_RS00140	COG0405	Gamma-glutamyltransferase
GPX93_RS00145	COG2962	Rard protein
GPX93_RS00150	COG0514	ATP-dependent DNA helicase (RecQ)
GPX93_RS00165	COG1132	(ABC) transporter
GPX93_RS00170	COG4774	siderophore transport
GPX93_RS00175	COG1120	ATPase activity
GPX93_RS00200	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPX93_RS00205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX93_RS00205	COG1263	PTS System
GPX93_RS00210	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPX93_RS00220	COG1561	YicC-like family, N-terminal region
GPX93_RS00225	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GPX93_RS00230	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPX93_RS00235	COG1560	Kdo2-lipid A biosynthetic process
GPX93_RS00240	COG1560	Kdo2-lipid A biosynthetic process
GPX93_RS00245	COG1309	transcriptional regulator
GPX93_RS00255	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPX93_RS00270	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GPX93_RS00275	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GPX93_RS00285	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GPX93_RS00290	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPX93_RS00295	COG0859	PFAM glycosyl transferase family 9
GPX93_RS00300	COG0463	Glycosyl transferase, family 2
GPX93_RS00305	COG0859	PFAM glycosyl transferase family 9
GPX93_RS00310	COG3642	lipopolysaccharide core region biosynthetic process
GPX93_RS00340	COG1519	Transferase
GPX93_RS00350	COG0859	PFAM glycosyl transferase family 9
GPX93_RS00375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPX93_RS00390	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GPX93_RS00415	COG0367	asparagine synthase
GPX93_RS00420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPX93_RS00460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPX93_RS00460	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GPX93_RS00475	COG1086	Polysaccharide biosynthesis protein
GPX93_RS00500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPX93_RS00510	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GPX93_RS00525	COG0668	transmembrane transport
GPX93_RS00530	COG1573	uracil-dna glycosylase
GPX93_RS00540	COG3068	Protein conserved in bacteria
GPX93_RS00545	COG1253	flavin adenine dinucleotide binding
GPX93_RS00550	COG0776	regulation of translation
GPX93_RS00560	COG0151	Belongs to the GarS family
GPX93_RS00565	COG0138	bifunctional purine biosynthesis protein purh
GPX93_RS00575	COG0789	Transcriptional regulator
GPX93_RS00580	COG3710	Transcriptional regulator
GPX93_RS00585	COG0531	amino acid
GPX93_RS00590	COG1982	Orn Lys Arg decarboxylase major
GPX93_RS00595	COG0840	transmembrane signaling receptor activity
GPX93_RS00615	COG0800	Aldolase
GPX93_RS00625	COG3265	gluconokinase activity
GPX93_RS00630	COG0129	dihydroxy-acid dehydratase activity
GPX93_RS00635	COG0387	Pfam Sodium calcium exchanger
GPX93_RS00645	COG1609	Transcriptional regulator
GPX93_RS00650	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GPX93_RS00655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPX93_RS00665	COG0439	Biotin carboxylase
GPX93_RS00670	COG0511	ligase activity, forming carbon-carbon bonds
GPX93_RS00675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GPX93_RS00680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPX93_RS00700	COG2814	Major facilitator Superfamily
GPX93_RS00705	COG0784	Response regulator, receiver
GPX93_RS00705	COG2205	protein histidine kinase activity
GPX93_RS00710	COG0248	Ppx GppA phosphatase
GPX93_RS00715	COG0513	Belongs to the DEAD box helicase family
GPX93_RS00720	COG3118	belongs to the thioredoxin family
GPX93_RS00725	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPX93_RS00735	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GPX93_RS00780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPX93_RS00790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GPX93_RS00800	COG1072	(Pantothenic acid kinase))
GPX93_RS00825	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPX93_RS00830	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPX93_RS00835	COG0250	Participates in transcription elongation, termination and antitermination
GPX93_RS00840	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPX93_RS00845	COG0081	regulation of translation
GPX93_RS00850	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPX93_RS00855	COG0222	ribosome binding
GPX93_RS00860	COG0085	RNA polymerase activity
GPX93_RS00865	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPX93_RS00870	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GPX93_RS00875	COG2816	NAD+ diphosphatase activity
GPX93_RS00880	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GPX93_RS00895	COG4942	peptidase
GPX93_RS00900	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPX93_RS00910	COG0471	metal ion transport
GPX93_RS00915	COG0688	phosphatidylethanolamine metabolic process
GPX93_RS00920	COG1162	GTPase activity
GPX93_RS00925	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GPX93_RS00975	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPX93_RS00980	COG0802	atpase or kinase
GPX93_RS00990	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPX93_RS00995	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPX93_RS01000	COG1923	regulation of RNA biosynthetic process
GPX93_RS01005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPX93_RS01010	COG0330	HflC and HflK could
GPX93_RS01015	COG0330	HflC and HflK could
GPX93_RS01020	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GPX93_RS01025	COG2900	Belongs to the SlyX family
GPX93_RS01035	COG0545	Peptidyl-prolyl cis-trans isomerase
GPX93_RS01040	COG2964	Protein conserved in bacteria
GPX93_RS01045	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GPX93_RS01050	COG2923	Belongs to the DsrF TusC family
GPX93_RS01060	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GPX93_RS01065	COG0049	tRNA binding
GPX93_RS01070	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPX93_RS01075	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPX93_RS01080	COG2906	2 iron, 2 sulfur cluster binding
GPX93_RS01090	COG0360	Binds together with S18 to 16S ribosomal RNA
GPX93_RS01095	COG2965	DNA replication, synthesis of RNA primer
GPX93_RS01100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GPX93_RS01105	COG0359	binds to the 23S rRNA
GPX93_RS01115	COG0305	Participates in initiation and elongation during chromosome replication
GPX93_RS01120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPX93_RS01125	COG0432	Pfam Uncharacterised protein family UPF0047
GPX93_RS01130	COG0166	Belongs to the GPI family
GPX93_RS01145	COG0735	belongs to the Fur family
GPX93_RS01150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPX93_RS01175	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPX93_RS01180	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPX93_RS01185	COG0175	sulfate reduction
GPX93_RS01265	COG0646	methionine synthase
GPX93_RS01265	COG1410	methionine synthase
GPX93_RS01270	COG0527	aspartate kinase activity
GPX93_RS01275	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPX93_RS01285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GPX93_RS01300	COG0629	single-stranded DNA binding
GPX93_RS01305	COG2200	EAL domain
GPX93_RS01305	COG2199	diguanylate cyclase activity
GPX93_RS01330	COG3267	Type II secretory pathway component ExeA
GPX93_RS01330	COG3409	Peptidoglycan-binding domain 1 protein
GPX93_RS01340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPX93_RS01345	COG1459	type II secretion system
GPX93_RS01390	COG1077	Cell shape determining protein MreB Mrl
GPX93_RS01395	COG1792	Involved in formation and maintenance of cell shape
GPX93_RS01400	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GPX93_RS01405	COG0424	maF-like protein
GPX93_RS01410	COG1530	ribonuclease E activity
GPX93_RS01415	COG3164	Protein of unknown function
GPX93_RS01420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPX93_RS01425	COG0312	modulator of DNA gyrase
GPX93_RS01430	COG2235	arginine
GPX93_RS01450	COG0589	response to stress
GPX93_RS01465	COG1438	arginine binding
GPX93_RS01470	COG0039	L-malate dehydrogenase activity
GPX93_RS01475	COG0531	amino acid
GPX93_RS01480	COG0142	geranyltranstransferase activity
GPX93_RS01485	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GPX93_RS01490	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GPX93_RS01495	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPX93_RS01500	COG2966	Psort location CytoplasmicMembrane, score
GPX93_RS01505	COG3610	response to peptide
GPX93_RS01515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GPX93_RS01520	COG2967	ApaG domain
GPX93_RS01525	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GPX93_RS01530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GPX93_RS01535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPX93_RS01540	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GPX93_RS01545	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPX93_RS01600	COG0741	lytic transglycosylase activity
GPX93_RS01605	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GPX93_RS01610	COG1194	a g-specific adenine glycosylase
GPX93_RS01615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GPX93_RS01620	COG2066	Belongs to the glutaminase family
GPX93_RS01625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPX93_RS01630	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPX93_RS01645	COG0762	integral membrane protein
GPX93_RS01650	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPX93_RS01655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPX93_RS01675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPX93_RS01680	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPX93_RS01685	COG1678	Uncharacterized ACR, COG1678
GPX93_RS01690	COG0189	ligase activity
GPX93_RS01695	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GPX93_RS01700	COG2356	endonuclease I
GPX93_RS01705	COG3091	SprT-like family
GPX93_RS01710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPX93_RS01715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPX93_RS01720	COG0583	DNA-binding transcription factor activity
GPX93_RS01725	COG4771	TonB-dependent receptor
GPX93_RS01730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPX93_RS01735	COG0126	phosphoglycerate kinase activity
GPX93_RS01740	COG0191	fructose-bisphosphate aldolase activity
GPX93_RS01750	COG0668	transmembrane transport
GPX93_RS01755	COG1279	arginine transmembrane transporter activity
GPX93_RS01760	COG0583	DNA-binding transcription factor activity
GPX93_RS01770	COG0469	pyruvate kinase activity
GPX93_RS01775	COG1349	DNA-binding transcription factor activity
GPX93_RS01780	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GPX93_RS01785	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GPX93_RS01800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPX93_RS01805	COG0358	DNA primase activity
GPX93_RS01810	COG1610	YqeY-like protein
GPX93_RS01815	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GPX93_RS01820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPX93_RS01830	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GPX93_RS01835	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPX93_RS01840	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPX93_RS01845	COG1968	undecaprenyl-diphosphatase activity
GPX93_RS01850	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GPX93_RS01855	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GPX93_RS01860	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GPX93_RS01865	COG0585	pseudouridine synthase activity
GPX93_RS01870	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GPX93_RS01875	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GPX93_RS01880	COG4942	peptidase
GPX93_RS01880	COG1388	LysM domain
GPX93_RS01885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPX93_RS01890	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPX93_RS01910	COG4208	sulfate ABC transporter
GPX93_RS01915	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GPX93_RS01925	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPX93_RS01930	COG2137	regulation of response to DNA damage stimulus
GPX93_RS01935	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPX93_RS01940	COG0527	aspartate kinase activity
GPX93_RS01945	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GPX93_RS01990	COG3630	sodium ion export across plasma membrane
GPX93_RS01995	COG5016	pyruvate
GPX93_RS01995	COG0511	ligase activity, forming carbon-carbon bonds
GPX93_RS02000	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GPX93_RS02010	COG1238	metal cluster binding
GPX93_RS02015	COG0612	Peptidase, M16
GPX93_RS02020	COG2918	glutathione biosynthetic process
GPX93_RS02025	COG1854	S-ribosylhomocysteine lyase activity
GPX93_RS02030	COG4536	flavin adenine dinucleotide binding
GPX93_RS02035	COG4137	Cytochrome C assembly protein
GPX93_RS02040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPX93_RS02045	COG0228	four-way junction DNA binding
GPX93_RS02050	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPX93_RS02055	COG0336	Belongs to the RNA methyltransferase TrmD family
GPX93_RS02060	COG0335	large ribosomal subunit rRNA binding
GPX93_RS02065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPX93_RS02070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPX93_RS02080	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GPX93_RS02085	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPX93_RS02090	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GPX93_RS02095	COG0723	plastoquinol--plastocyanin reductase activity
GPX93_RS02100	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GPX93_RS02105	COG2857	Cytochrome c1
GPX93_RS02110	COG0625	glutathione transferase activity
GPX93_RS02115	COG2969	positive regulation of protein catabolic process
GPX93_RS02120	COG2823	Periplasmic or secreted lipoprotein
GPX93_RS02125	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPX93_RS02130	COG0792	nuclease activity
GPX93_RS02135	COG3107	peptidoglycan biosynthetic process
GPX93_RS02140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPX93_RS02155	COG0288	reversible hydration of carbon dioxide
GPX93_RS02160	COG0659	secondary active sulfate transmembrane transporter activity
GPX93_RS02165	COG1131	(ABC) transporter
GPX93_RS02170	COG0842	Transport permease protein
GPX93_RS02175	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GPX93_RS02180	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GPX93_RS02185	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPX93_RS02195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPX93_RS02200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPX93_RS02205	COG1489	DNA binding
GPX93_RS02215	COG1643	Atp-dependent helicase
GPX93_RS02220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPX93_RS02225	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPX93_RS02230	COG1049	propionate catabolic process, 2-methylcitrate cycle
GPX93_RS02235	COG3112	Uncharacterised protein family (UPF0231)
GPX93_RS02240	COG0347	Belongs to the P(II) protein family
GPX93_RS02245	COG0004	ammonium transporteR
GPX93_RS02250	COG1840	ABC-type Fe3 transport system, periplasmic component
GPX93_RS02260	COG3842	ATPase activity
GPX93_RS02280	COG2971	BadF BadG BcrA BcrD
GPX93_RS02290	COG4608	Belongs to the ABC transporter superfamily
GPX93_RS02295	COG0444	Belongs to the ABC transporter superfamily
GPX93_RS02300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPX93_RS02305	COG0601	transmembrane transport
GPX93_RS02310	COG0747	negative chemotaxis
GPX93_RS02320	COG2813	Specifically methylates the guanine in position
GPX93_RS02325	COG0628	permease
GPX93_RS02335	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GPX93_RS02340	COG0316	Belongs to the HesB IscA family
GPX93_RS02350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPX93_RS02355	COG0739	heme binding
GPX93_RS02360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPX93_RS02365	COG2027	D-alanyl-D-alanine carboxypeptidase
GPX93_RS02370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPX93_RS02375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPX93_RS02380	COG1534	Rna-binding protein
GPX93_RS02385	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GPX93_RS02390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPX93_RS02395	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPX93_RS02400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPX93_RS02405	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPX93_RS02420	COG0779	Required for maturation of 30S ribosomal subunits
GPX93_RS02425	COG0195	Participates in both transcription termination and antitermination
GPX93_RS02430	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPX93_RS02435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPX93_RS02440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPX93_RS02445	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPX93_RS02450	COG1185	polyribonucleotide nucleotidyltransferase activity
GPX93_RS02455	COG4785	May be involved in cell division
GPX93_RS02490	COG3153	acetyltransferase
GPX93_RS02510	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GPX93_RS02515	COG0513	Belongs to the DEAD box helicase family
GPX93_RS02520	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GPX93_RS02535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GPX93_RS02540	COG2204	response regulator
GPX93_RS02555	COG0667	Aldo Keto reductase
GPX93_RS02560	COG3066	DNA modification
GPX93_RS02565	COG0494	nUDIX hydrolase
GPX93_RS02570	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GPX93_RS02575	COG0730	response to heat
GPX93_RS02580	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPX93_RS02585	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GPX93_RS02590	COG1283	sodium-dependent phosphate transmembrane transporter activity
GPX93_RS02595	COG0583	DNA-binding transcription factor activity
GPX93_RS02600	COG0640	Transcriptional regulator
GPX93_RS02605	COG0268	Binds directly to 16S ribosomal RNA
GPX93_RS02610	COG0728	peptidoglycan biosynthetic process
GPX93_RS02615	COG0196	riboflavin kinase activity
GPX93_RS02620	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPX93_RS02625	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPX93_RS02630	COG1047	Peptidyl-prolyl cis-trans
GPX93_RS02635	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GPX93_RS02640	COG1966	Carbon starvation protein
GPX93_RS02655	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPX93_RS02660	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GPX93_RS02665	COG1472	Belongs to the glycosyl hydrolase 3 family
GPX93_RS02670	COG3279	Response regulator of the LytR AlgR family
GPX93_RS02675	COG3275	phosphorelay sensor kinase activity
GPX93_RS02680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPX93_RS02685	COG0287	Prephenate dehydrogenase
GPX93_RS02685	COG1605	Chorismate mutase
GPX93_RS02695	COG0488	(ABC) transporter
GPX93_RS02705	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GPX93_RS02710	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GPX93_RS02715	COG5001	Diguanylate cyclase
GPX93_RS02720	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPX93_RS02725	COG1605	Chorismate mutase
GPX93_RS02725	COG0077	Prephenate dehydratase
GPX93_RS02730	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPX93_RS02735	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPX93_RS02740	COG0564	pseudouridine synthase activity
GPX93_RS02750	COG0542	response to heat
GPX93_RS02790	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPX93_RS02800	COG2974	May be involved in recombination
GPX93_RS02805	COG0745	RESPONSE REGULATOR receiver
GPX93_RS02810	COG5002	protein histidine kinase activity
GPX93_RS02820	COG0248	Ppx GppA phosphatase
GPX93_RS02825	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GPX93_RS02835	COG0581	inorganic phosphate transmembrane transporter activity
GPX93_RS02840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPX93_RS02855	COG3142	Participates in the control of copper homeostasis
GPX93_RS02860	COG0450	alkyl hydroperoxide reductase
GPX93_RS02865	COG0583	DNA-binding transcription factor activity
GPX93_RS02870	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GPX93_RS02880	COG0517	IMP dehydrogenase activity
GPX93_RS02885	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPX93_RS02890	COG0343	queuine tRNA-ribosyltransferase activity
GPX93_RS02895	COG1862	Preprotein translocase
GPX93_RS02900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPX93_RS02905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPX93_RS02910	COG0483	inositol monophosphate 1-phosphatase activity
GPX93_RS02920	COG1959	2 iron, 2 sulfur cluster binding
GPX93_RS02930	COG0822	iron-sulfur transferase activity
GPX93_RS02950	COG0633	Ferredoxin
GPX93_RS02955	COG2975	iron-sulfur cluster assembly
GPX93_RS02960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPX93_RS02965	COG0105	UTP biosynthetic process
GPX93_RS02980	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GPX93_RS02985	COG0124	histidyl-tRNA synthetase
GPX93_RS02990	COG2976	Protein conserved in bacteria
GPX93_RS02995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPX93_RS03000	COG1160	GTP binding
GPX93_RS03015	COG1570	exodeoxyribonuclease VII activity
GPX93_RS03020	COG0516	GMP reductase activity
GPX93_RS03020	COG0517	IMP dehydrogenase activity
GPX93_RS03025	COG0519	Catalyzes the synthesis of GMP from XMP
GPX93_RS03025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GPX93_RS03035	COG1584	GPR1 FUN34 yaaH family protein
GPX93_RS03040	COG1535	isochorismatase
GPX93_RS03040	COG3433	isochorismatase activity
GPX93_RS03045	COG1021	2,3-dihydroxybenzoate-AMP ligase
GPX93_RS03050	COG1169	isochorismate synthase
GPX93_RS03055	COG1028	Short-chain dehydrogenase reductase Sdr
GPX93_RS03065	COG4592	Periplasmic binding protein
GPX93_RS03070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPX93_RS03075	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPX93_RS03080	COG1120	ATPase activity
GPX93_RS03090	COG0583	DNA-binding transcription factor activity
GPX93_RS03095	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GPX93_RS03100	COG1115	amino acid carrier protein
GPX93_RS03105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPX93_RS03110	COG0583	DNA-binding transcription factor activity
GPX93_RS03125	COG4565	transcriptional regulatory protein
GPX93_RS03135	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GPX93_RS03140	COG5016	pyruvate
GPX93_RS03140	COG0511	ligase activity, forming carbon-carbon bonds
GPX93_RS03145	COG3630	sodium ion export across plasma membrane
GPX93_RS03155	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GPX93_RS03160	COG3052	prosthetic group binding
GPX93_RS03165	COG2301	Belongs to the HpcH HpaI aldolase family
GPX93_RS03170	COG3051	citrate lyase alpha subunit
GPX93_RS03175	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
GPX93_RS03180	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GPX93_RS03190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPX93_RS03195	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GPX93_RS03200	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GPX93_RS03225	COG0514	ATP-dependent DNA helicase (RecQ)
GPX93_RS03280	COG0328	RNA-DNA hybrid ribonuclease activity
GPX93_RS03325	COG2003	Belongs to the UPF0758 family
GPX93_RS03370	COG0582	viral genome integration into host DNA
GPX93_RS03380	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GPX93_RS03385	COG2867	negative regulation of translational initiation
GPX93_RS03390	COG2914	Belongs to the UPF0125 (RnfH) family
GPX93_RS03395	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPX93_RS03400	COG0497	DNA recombination
GPX93_RS03405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPX93_RS03410	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPX93_RS03415	COG0443	Heat shock 70 kDa protein
GPX93_RS03420	COG0484	heat shock protein binding
GPX93_RS03455	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPX93_RS03460	COG0590	tRNA wobble adenosine to inosine editing
GPX93_RS03465	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GPX93_RS03475	COG0047	phosphoribosylformylglycinamidine synthase activity
GPX93_RS03475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPX93_RS03495	COG0442	prolyl-tRNA aminoacylation
GPX93_RS03500	COG1720	tRNA m6t6A37 methyltransferase activity
GPX93_RS03505	COG0254	rRNA binding
GPX93_RS03510	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GPX93_RS03515	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPX93_RS03520	COG1671	Belongs to the UPF0178 family
GPX93_RS03530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPX93_RS03545	COG3098	single-species biofilm formation
GPX93_RS03550	COG0564	pseudouridine synthase activity
GPX93_RS03555	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPX93_RS03560	COG0142	geranyltranstransferase activity
GPX93_RS03565	COG1722	exodeoxyribonuclease VII activity
GPX93_RS03570	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPX93_RS03580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPX93_RS03580	COG0301	tRNA thio-modification
GPX93_RS03585	COG0583	DNA-binding transcription factor activity
GPX93_RS03590	COG2363	Small membrane protein
GPX93_RS03595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPX93_RS03600	COG1611	Belongs to the LOG family
GPX93_RS03605	COG3706	GGDEF domain
GPX93_RS03615	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPX93_RS03615	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPX93_RS03625	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GPX93_RS03630	COG1464	Belongs to the NlpA lipoprotein family
GPX93_RS03635	COG2011	ABC-type metal ion transport system permease component
GPX93_RS03640	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPX93_RS03645	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPX93_RS03650	COG1609	Transcriptional regulator
GPX93_RS03655	COG1263	PTS System
GPX93_RS03655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX93_RS03660	COG0366	Alpha amylase catalytic
GPX93_RS03690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPX93_RS03695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPX93_RS03700	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GPX93_RS03705	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GPX93_RS03710	COG0110	maltose O-acetyltransferase activity
GPX93_RS03730	COG1045	serine acetyltransferase
GPX93_RS03740	COG0438	transferase activity, transferring glycosyl groups
GPX93_RS03750	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GPX93_RS03780	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPX93_RS03790	COG1596	polysaccharide export
GPX93_RS03815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPX93_RS03825	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GPX93_RS03830	COG0321	lipoyl(octanoyl) transferase activity
GPX93_RS03835	COG2921	Belongs to the UPF0250 family
GPX93_RS03840	COG1686	Belongs to the peptidase S11 family
GPX93_RS03845	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPX93_RS03850	COG0772	Belongs to the SEDS family
GPX93_RS03855	COG0768	penicillin binding
GPX93_RS03860	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPX93_RS03865	COG0799	negative regulation of ribosome biogenesis
GPX93_RS03870	COG1466	dna polymerase III delta subunit
GPX93_RS03875	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GPX93_RS03880	COG0495	leucyl-tRNA aminoacylation
GPX93_RS03885	COG2888	peptidyl-tyrosine sulfation
GPX93_RS03890	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GPX93_RS03895	COG4535	Mg2 and Co2 transporter CorC
GPX93_RS03900	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPX93_RS03905	COG1702	phosphate starvation-inducible protein PhoH
GPX93_RS03910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPX93_RS03915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPX93_RS03920	COG2190	(PTS) system
GPX93_RS03930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX93_RS03940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPX93_RS03945	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GPX93_RS03950	COG3115	cell septum assembly
GPX93_RS03955	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPX93_RS03970	COG0789	Transcriptional regulator
GPX93_RS03975	COG1585	Membrane protein implicated in regulation of membrane protease activity
GPX93_RS03980	COG0330	HflC and HflK could
GPX93_RS03985	COG3118	belongs to the thioredoxin family
GPX93_RS03995	COG0300	oxidoreductase activity
GPX93_RS04000	COG1090	epimerase
GPX93_RS04005	COG0622	Phosphoesterase
GPX93_RS04020	COG3710	Transcriptional regulator
GPX93_RS04025	COG0326	Molecular chaperone. Has ATPase activity
GPX93_RS04030	COG0563	adenylate kinase activity
GPX93_RS04035	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GPX93_RS04050	COG0367	asparagine synthase
GPX93_RS04055	COG4651	solute:proton antiporter activity
GPX93_RS04055	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPX93_RS04060	COG1940	carbohydrate kinase activity
GPX93_RS04060	COG1846	Transcriptional regulator
GPX93_RS04065	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPX93_RS04070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX93_RS04070	COG1263	PTS System
GPX93_RS04070	COG2190	(PTS) system
GPX93_RS04075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPX93_RS04085	COG0101	tRNA pseudouridine synthase activity
GPX93_RS04090	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPX93_RS04095	COG0285	dihydrofolate synthase activity
GPX93_RS04100	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GPX93_RS04105	COG1286	toxin biosynthetic process
GPX93_RS04110	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPX93_RS04115	COG2056	Na+-H+ antiporter family
GPX93_RS04120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPX93_RS04135	COG0346	lactoylglutathione lyase activity
GPX93_RS04140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPX93_RS04145	COG4660	Part of a membrane complex involved in electron transport
GPX93_RS04150	COG4659	FMN binding
GPX93_RS04155	COG4658	electron transport chain
GPX93_RS04160	COG4656	Part of a membrane complex involved in electron transport
GPX93_RS04165	COG2878	Part of a membrane complex involved in electron transport
GPX93_RS04170	COG4657	Part of a membrane complex involved in electron transport
GPX93_RS04180	COG0556	nucleotide-excision repair
GPX93_RS04185	COG2204	response regulator
GPX93_RS04190	COG2198	Histidine kinase
GPX93_RS04195	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GPX93_RS04200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPX93_RS04205	COG0521	Mo-molybdopterin cofactor biosynthetic process
GPX93_RS04210	COG0315	cyclic pyranopterin monophosphate synthase activity
GPX93_RS04215	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPX93_RS04220	COG0314	molybdopterin synthase activity
GPX93_RS04225	COG2199	diguanylate cyclase activity
GPX93_RS04230	COG4109	DRTGG domain
GPX93_RS04240	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GPX93_RS04255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPX93_RS04255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPX93_RS04260	COG0489	protein tyrosine kinase activity
GPX93_RS04265	COG0572	uridine kinase
GPX93_RS04270	COG2982	Protein involved in outer membrane biogenesis
GPX93_RS04275	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GPX93_RS04280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPX93_RS04290	COG2067	long-chain fatty acid transport protein
GPX93_RS04305	COG0183	Belongs to the thiolase family
GPX93_RS04310	COG1024	Enoyl-CoA hydratase
GPX93_RS04310	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPX93_RS04315	COG0778	Nitroreductase
GPX93_RS04320	COG0583	DNA-binding transcription factor activity
GPX93_RS04325	COG0745	RESPONSE REGULATOR receiver
GPX93_RS04335	COG2832	Protein of unknown function (DUF454)
GPX93_RS04340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPX93_RS04345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPX93_RS04350	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPX93_RS04355	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPX93_RS04370	COG1028	Short-chain dehydrogenase reductase Sdr
GPX93_RS04375	COG0616	signal peptide processing
GPX93_RS04385	COG1522	sequence-specific DNA binding
GPX93_RS04390	COG1946	Acyl-CoA thioesterase
GPX93_RS04410	COG3706	GGDEF domain
GPX93_RS04420	COG0640	Transcriptional regulator
GPX93_RS04425	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPX93_RS04450	COG1881	PFAM PEBP family protein
GPX93_RS04470	COG0009	L-threonylcarbamoyladenylate synthase
GPX93_RS04485	COG2201	protein-glutamate methylesterase activity
GPX93_RS04495	COG5002	protein histidine kinase activity
GPX93_RS04500	COG4191	Histidine kinase
GPX93_RS04505	COG5001	Diguanylate cyclase
GPX93_RS04505	COG3300	MHYT domain
GPX93_RS04510	COG2204	response regulator
GPX93_RS04530	COG0601	transmembrane transport
GPX93_RS04535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPX93_RS04540	COG0444	Belongs to the ABC transporter superfamily
GPX93_RS04545	COG4608	Belongs to the ABC transporter superfamily
GPX93_RS04550	COG0435	Glutathione S-transferase
GPX93_RS04555	COG0280	phosphate acetyltransferase
GPX93_RS04555	COG0857	belongs to the CobB CobQ family
GPX93_RS04560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPX93_RS04565	COG3092	negative regulation of chromosome organization
GPX93_RS04570	COG4628	conserved protein (DUF2132)
GPX93_RS04580	COG4120	Belongs to the binding-protein-dependent transport system permease family
GPX93_RS04595	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPX93_RS04605	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GPX93_RS04610	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GPX93_RS04615	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPX93_RS04620	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GPX93_RS04625	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPX93_RS04630	COG0156	8-amino-7-oxononanoate synthase activity
GPX93_RS04635	COG2226	methyltransferase
GPX93_RS04640	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GPX93_RS04650	COG0501	Belongs to the peptidase M48B family
GPX93_RS04660	COG0300	oxidoreductase activity
GPX93_RS04675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GPX93_RS04685	COG2268	Band 7 protein
GPX93_RS04695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPX93_RS04700	COG2915	High frequency lysogenization protein hflD homolog
GPX93_RS04705	COG0482	sulfurtransferase activity
GPX93_RS04710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPX93_RS04715	COG2916	Histone family protein nucleoid-structuring protein H-NS
GPX93_RS04720	COG1757	Na H antiporter
GPX93_RS04725	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GPX93_RS04730	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPX93_RS04735	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPX93_RS04740	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPX93_RS04740	COG0131	Imidazoleglycerol-phosphate dehydratase
GPX93_RS04745	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPX93_RS04750	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPX93_RS04755	COG0107	imidazoleglycerol-phosphate synthase activity
GPX93_RS04760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GPX93_RS04760	COG0140	phosphoribosyl-ATP diphosphatase activity
GPX93_RS04765	COG1187	pseudouridine synthase activity
GPX93_RS04775	COG1278	Cold shock
GPX93_RS04780	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GPX93_RS04785	COG0542	response to heat
GPX93_RS04795	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPX93_RS04800	COG1454	alcohol dehydrogenase
GPX93_RS04800	COG1012	belongs to the aldehyde dehydrogenase family
GPX93_RS04805	COG1737	Transcriptional regulator
GPX93_RS04810	COG0076	glutamate decarboxylase activity
GPX93_RS04820	COG2431	L-lysine efflux transmembrane transporter activity
GPX93_RS04830	COG3070	regulator of competence-specific genes
GPX93_RS04845	COG3852	Histidine kinase
GPX93_RS04855	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPX93_RS04870	COG4067	protein conserved in archaea
GPX93_RS04870	COG0189	ligase activity
GPX93_RS04875	COG0500	methyltransferase
GPX93_RS04880	COG4106	trans-aconitate 2-methyltransferase activity
GPX93_RS04885	COG1801	Protein of unknown function DUF72
GPX93_RS04890	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GPX93_RS04895	COG1435	thymidine kinase activity
GPX93_RS04905	COG0159	tryptophan synthase activity
GPX93_RS04910	COG0133	tryptophan synthase activity
GPX93_RS04915	COG0135	phosphoribosylanthranilate isomerase activity
GPX93_RS04915	COG0134	indole-3-glycerol-phosphate synthase activity
GPX93_RS04920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GPX93_RS04925	COG0512	Glutamine amidotransferase of anthranilate synthase
GPX93_RS04930	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPX93_RS04940	COG0613	PHP domain protein
GPX93_RS04945	COG0009	L-threonylcarbamoyladenylate synthase
GPX93_RS04950	COG1187	pseudouridine synthase activity
GPX93_RS04955	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GPX93_RS04960	COG4988	ABC transporter
GPX93_RS04965	COG0492	ferredoxin-NADP+ reductase activity
GPX93_RS04975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPX93_RS04980	COG3706	GGDEF domain
GPX93_RS04985	COG2949	membrane
GPX93_RS04995	COG0281	malic enzyme
GPX93_RS05005	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GPX93_RS05025	COG2885	chlorophyll binding
GPX93_RS05040	COG0247	lactate metabolic process
GPX93_RS05040	COG0277	FAD linked oxidase domain protein
GPX93_RS05060	COG2986	histidine ammonia-lyase
GPX93_RS05065	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GPX93_RS05070	COG0010	Belongs to the arginase family
GPX93_RS05075	COG1228	amidohydrolase
GPX93_RS05095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPX93_RS05110	COG0417	DNA replication proofreading
GPX93_RS05115	COG2197	response regulator
GPX93_RS05120	COG0322	excinuclease ABC activity
GPX93_RS05150	COG3706	GGDEF domain
GPX93_RS05150	COG0745	RESPONSE REGULATOR receiver
GPX93_RS05160	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPX93_RS05165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPX93_RS05165	COG0072	phenylalanine-tRNA ligase activity
GPX93_RS05170	COG0776	regulation of translation
GPX93_RS05185	COG0500	methyltransferase
GPX93_RS05205	COG0295	cytidine deaminase activity
GPX93_RS05210	COG1346	cytolysis
GPX93_RS05220	COG2925	Exonuclease
GPX93_RS05230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPX93_RS05235	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GPX93_RS05240	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GPX93_RS05255	COG2988	succinylglutamate desuccinylase activity
GPX93_RS05260	COG4139	cobalamin transport
GPX93_RS05265	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GPX93_RS05310	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPX93_RS05315	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPX93_RS05320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPX93_RS05340	COG2814	Major facilitator Superfamily
GPX93_RS05350	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPX93_RS05380	COG3108	Peptidase M15
GPX93_RS05385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPX93_RS05400	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GPX93_RS05425	COG1846	Transcriptional regulator
GPX93_RS05430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPX93_RS05435	COG0726	polysaccharide deacetylase
GPX93_RS05440	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPX93_RS05450	COG1447	Phosphotransferase system cellobiose-specific component IIA
GPX93_RS05455	COG1486	melibiose metabolic process
GPX93_RS05460	COG3394	polysaccharide catabolic process
GPX93_RS05465	COG1609	Transcriptional regulator
GPX93_RS05470	COG2943	transferase activity, transferring hexosyl groups
GPX93_RS05475	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GPX93_RS05480	COG0840	transmembrane signaling receptor activity
GPX93_RS05495	COG1448	Aminotransferase
GPX93_RS05505	COG3437	response regulator, receiver
GPX93_RS05505	COG2770	Histidine kinase
GPX93_RS05510	COG0351	phosphomethylpyrimidine kinase
GPX93_RS05515	COG0017	Asparaginyl-tRNA synthetase
GPX93_RS05525	COG0720	synthase
GPX93_RS05530	COG1760	l-serine dehydratase
GPX93_RS05535	COG0814	amino acid
GPX93_RS05540	COG0494	nUDIX hydrolase
GPX93_RS05545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPX93_RS05560	COG3106	COG3106 Predicted ATPase
GPX93_RS05565	COG3768	UPF0283 membrane protein
GPX93_RS05570	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GPX93_RS05575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPX93_RS05590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPX93_RS05600	COG0471	metal ion transport
GPX93_RS05605	COG4191	Histidine kinase
GPX93_RS05605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX93_RS05615	COG2990	Protein conserved in bacteria
GPX93_RS05620	COG3713	MltA-interacting MipA family protein
GPX93_RS05625	COG5002	protein histidine kinase activity
GPX93_RS05630	COG0745	RESPONSE REGULATOR receiver
GPX93_RS05655	COG1129	ABC transporter
GPX93_RS05690	COG2186	Transcriptional regulator
GPX93_RS05695	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPX93_RS05700	COG0372	Belongs to the citrate synthase family
GPX93_RS05730	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPX93_RS05740	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GPX93_RS05750	COG0625	glutathione transferase activity
GPX93_RS05755	COG3437	response regulator, receiver
GPX93_RS05760	COG4999	Histidine kinase
GPX93_RS05760	COG3437	response regulator, receiver
GPX93_RS05760	COG2205	protein histidine kinase activity
GPX93_RS05760	COG3850	Histidine kinase
GPX93_RS05765	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPX93_RS05765	COG0678	peroxiredoxin activity
GPX93_RS05770	COG3706	GGDEF domain
GPX93_RS05775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPX93_RS05780	COG1254	Belongs to the acylphosphatase family
GPX93_RS05785	COG2920	part of a sulfur-relay system
GPX93_RS05790	COG0670	Belongs to the BI1 family
GPX93_RS05795	COG1126	abc transporter atp-binding protein
GPX93_RS05800	COG0765	amino acid transport
GPX93_RS05805	COG4597	amino acid ABC transporter
GPX93_RS05810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX93_RS05820	COG0561	phosphatase activity
GPX93_RS05825	COG0602	queuosine metabolic process
GPX93_RS05830	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GPX93_RS05860	COG3706	GGDEF domain
GPX93_RS05865	COG0443	Heat shock 70 kDa protein
GPX93_RS05905	COG1643	Atp-dependent helicase
GPX93_RS05915	COG0443	Heat shock 70 kDa protein
GPX93_RS05920	COG0095	Lipoate-protein ligase
GPX93_RS05925	COG0402	S-adenosylhomocysteine deaminase activity
GPX93_RS05935	COG0583	DNA-binding transcription factor activity
GPX93_RS05940	COG0477	Major facilitator Superfamily
GPX93_RS05945	COG0415	Belongs to the DNA photolyase family
GPX93_RS05950	COG2076	Multidrug Resistance protein
GPX93_RS05970	COG2198	Histidine kinase
GPX93_RS05970	COG0643	Histidine kinase
GPX93_RS05980	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPX93_RS05990	COG2201	protein-glutamate methylesterase activity
GPX93_RS05995	COG0835	chemotaxis
GPX93_RS06000	COG0840	transmembrane signaling receptor activity
GPX93_RS06005	COG0840	transmembrane signaling receptor activity
GPX93_RS06015	COG0513	Belongs to the DEAD box helicase family
GPX93_RS06025	COG1538	Outer membrane efflux protein
GPX93_RS06030	COG1566	PFAM secretion protein HlyD family protein
GPX93_RS06035	COG2814	Major facilitator Superfamily
GPX93_RS06040	COG0840	transmembrane signaling receptor activity
GPX93_RS06045	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GPX93_RS06055	COG3501	Rhs element vgr protein
GPX93_RS06075	COG1280	lysine exporter protein (LysE YggA)
GPX93_RS06080	COG1115	amino acid carrier protein
GPX93_RS06095	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPX93_RS06100	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPX93_RS06105	COG1177	transmembrane transport
GPX93_RS06110	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPX93_RS06115	COG3842	ATPase activity
GPX93_RS06135	COG0037	tRNA processing
GPX93_RS06140	COG0589	response to stress
GPX93_RS06145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPX93_RS06160	COG2217	Heavy metal translocating P-type atpase
GPX93_RS06170	COG2010	Cytochrome c
GPX93_RS06185	COG3278	Belongs to the heme-copper respiratory oxidase family
GPX93_RS06200	COG2205	protein histidine kinase activity
GPX93_RS06200	COG0784	Response regulator, receiver
GPX93_RS06225	COG2994	toxin metabolic process
GPX93_RS06230	COG1073	alpha beta
GPX93_RS06230	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GPX93_RS06230	COG3064	Membrane
GPX93_RS06265	COG3120	sequence-specific DNA binding
GPX93_RS06270	COG1067	ATP-dependent peptidase activity
GPX93_RS06275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPX93_RS06300	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPX93_RS06300	COG0116	Belongs to the methyltransferase superfamily
GPX93_RS06310	COG0167	dihydroorotate dehydrogenase activity
GPX93_RS06325	COG0308	aminopeptidase N
GPX93_RS06340	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GPX93_RS06345	COG1956	GAF domain-containing protein
GPX93_RS06350	COG1132	(ABC) transporter
GPX93_RS06355	COG2995	paraquat-inducible protein a
GPX93_RS06360	COG3008	intermembrane lipid transfer
GPX93_RS06365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPX93_RS06365	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GPX93_RS06370	COG2996	Protein conserved in bacteria
GPX93_RS06385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPX93_RS06395	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GPX93_RS06410	COG0437	4 iron, 4 sulfur cluster binding
GPX93_RS06415	COG0243	molybdopterin cofactor binding
GPX93_RS06415	COG3383	formate dehydrogenase (NAD+) activity
GPX93_RS06445	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPX93_RS06450	COG0488	(ABC) transporter
GPX93_RS06455	COG3852	Histidine kinase
GPX93_RS06460	COG2204	response regulator
GPX93_RS06470	COG4662	Binding-protein-dependent transport system inner membrane component
GPX93_RS06475	COG3842	ATPase activity
GPX93_RS06480	COG0746	molybdenum cofactor guanylyltransferase activity
GPX93_RS06485	COG0303	'Molybdopterin
GPX93_RS06495	COG1940	carbohydrate kinase activity
GPX93_RS06510	COG0840	transmembrane signaling receptor activity
GPX93_RS06515	COG0791	NLP P60 protein
GPX93_RS06535	COG0534	Mate efflux family protein
GPX93_RS06545	COG1793	dna ligase
GPX93_RS06555	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GPX93_RS06560	COG0848	biopolymer transport protein
GPX93_RS06565	COG0811	peptide transport
GPX93_RS06570	COG0811	peptide transport
GPX93_RS06585	COG1175	transmembrane transport
GPX93_RS06590	COG0395	ABC-type sugar transport system, permease component
GPX93_RS06595	COG3842	ATPase activity
GPX93_RS06600	COG1349	DNA-binding transcription factor activity
GPX93_RS06605	COG0584	glycerophosphoryl diester phosphodiesterase
GPX93_RS06610	COG2731	YhcH YjgK YiaL family protein
GPX93_RS06615	COG0251	oxidation-reduction process
GPX93_RS06620	COG1609	Transcriptional regulator
GPX93_RS06625	COG2723	6-phospho-beta-galactosidase activity
GPX93_RS06630	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GPX93_RS06635	COG0583	DNA-binding transcription factor activity
GPX93_RS06655	COG0577	efflux transmembrane transporter activity
GPX93_RS06655	COG1136	(ABC) transporter
GPX93_RS06660	COG1136	(ABC) transporter
GPX93_RS06660	COG0577	efflux transmembrane transporter activity
GPX93_RS06665	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPX93_RS06665	COG1136	(ABC) transporter
GPX93_RS06670	COG1294	oxidase, subunit
GPX93_RS06675	COG1271	oxidase subunit
GPX93_RS06715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPX93_RS06725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GPX93_RS06740	COG3527	Alpha-acetolactate decarboxylase
GPX93_RS06755	COG2200	EAL domain
GPX93_RS06755	COG2199	diguanylate cyclase activity
GPX93_RS06760	COG3706	GGDEF domain
GPX93_RS06765	COG2017	converts alpha-aldose to the beta-anomer
GPX93_RS06770	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPX93_RS06775	COG1085	galactose-1-phosphate uridylyltransferase
GPX93_RS06800	COG3706	GGDEF domain
GPX93_RS06800	COG0745	RESPONSE REGULATOR receiver
GPX93_RS06820	COG0784	Response regulator, receiver
GPX93_RS06820	COG0835	chemotaxis
GPX93_RS06830	COG4565	transcriptional regulatory protein
GPX93_RS06835	COG3290	protein histidine kinase activity
GPX93_RS06850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPX93_RS06870	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GPX93_RS06875	COG3063	Type IV pilus biogenesis stability protein PilW
GPX93_RS06890	COG1451	nucleotide metabolic process
GPX93_RS06900	COG0583	DNA-binding transcription factor activity
GPX93_RS06930	COG1538	Outer membrane efflux protein
GPX93_RS06940	COG0019	diaminopimelate decarboxylase activity
GPX93_RS06945	COG1748	Saccharopine dehydrogenase
GPX93_RS06955	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPX93_RS06970	COG4181	ATPase activity
GPX93_RS06975	COG0534	Mate efflux family protein
GPX93_RS06980	COG0702	epimerase
GPX93_RS06990	COG2814	Major facilitator Superfamily
GPX93_RS06995	COG1187	pseudouridine synthase activity
GPX93_RS07000	COG1061	Type III restriction enzyme res subunit
GPX93_RS07015	COG5002	protein histidine kinase activity
GPX93_RS07020	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GPX93_RS07025	COG3706	GGDEF domain
GPX93_RS07025	COG4251	negative regulation of phosphorylation
GPX93_RS07025	COG2203	Gaf domain
GPX93_RS07025	COG5001	Diguanylate cyclase
GPX93_RS07035	COG0840	transmembrane signaling receptor activity
GPX93_RS07070	COG4934	collagen metabolic process
GPX93_RS07090	COG2239	Acts as a magnesium transporter
GPX93_RS07100	COG0814	amino acid
GPX93_RS07105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPX93_RS07110	COG1131	(ABC) transporter
GPX93_RS07115	COG0842	Transport permease protein
GPX93_RS07125	COG3313	Fe-S protein
GPX93_RS07135	COG4134	Bacterial extracellular solute-binding protein
GPX93_RS07140	COG4135	transport system, permease component
GPX93_RS07145	COG4136	ATPase activity
GPX93_RS07150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPX93_RS07155	COG0564	pseudouridine synthase activity
GPX93_RS07160	COG0733	neurotransmitter:sodium symporter activity
GPX93_RS07170	COG0626	cystathionine gamma-synthase activity
GPX93_RS07175	COG2818	Glycosylase
GPX93_RS07190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPX93_RS07205	COG1842	Phage shock protein A
GPX93_RS07210	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GPX93_RS07220	COG4168	peptide transport system, permease
GPX93_RS07225	COG4171	peptide transport system, permease
GPX93_RS07235	COG4172	Belongs to the ABC transporter superfamily
GPX93_RS07250	COG1227	inorganic diphosphatase activity
GPX93_RS07265	COG0243	molybdopterin cofactor binding
GPX93_RS07270	COG3005	denitrification pathway
GPX93_RS07275	COG4459	periplasmic nitrate reductase
GPX93_RS07285	COG2116	formate transmembrane transporter activity
GPX93_RS07295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPX93_RS07300	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPX93_RS07310	COG2917	probably involved in intracellular septation
GPX93_RS07315	COG1607	acyl-coa hydrolase
GPX93_RS07320	COG2350	Protein conserved in bacteria
GPX93_RS07330	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPX93_RS07335	COG0583	DNA-binding transcription factor activity
GPX93_RS07350	COG0612	Peptidase, M16
GPX93_RS07355	COG5001	Diguanylate cyclase
GPX93_RS07360	COG1032	radical SAM domain protein
GPX93_RS07380	COG2207	Transcriptional regulator
GPX93_RS07385	COG1979	alcohol dehydrogenase
GPX93_RS07390	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GPX93_RS07395	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GPX93_RS07400	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GPX93_RS07405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPX93_RS07410	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPX93_RS07415	COG0745	RESPONSE REGULATOR receiver
GPX93_RS07425	COG1609	Transcriptional regulator
GPX93_RS07430	COG3070	regulator of competence-specific genes
GPX93_RS07450	COG0297	glycogen (starch) synthase activity
GPX93_RS07455	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPX93_RS07460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPX93_RS07470	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GPX93_RS07480	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GPX93_RS07485	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GPX93_RS07490	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPX93_RS07495	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPX93_RS07500	COG1960	acyl-CoA dehydrogenase activity
GPX93_RS07520	COG1012	belongs to the aldehyde dehydrogenase family
GPX93_RS07525	COG1309	transcriptional regulator
GPX93_RS07545	COG0668	transmembrane transport
GPX93_RS07550	COG2995	paraquat-inducible protein a
GPX93_RS07555	COG3008	intermembrane lipid transfer
GPX93_RS07555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPX93_RS07565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPX93_RS07570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPX93_RS07580	COG0582	viral genome integration into host DNA
GPX93_RS07660	COG4790	Type iii secretion
GPX93_RS07670	COG3710	Transcriptional regulator
GPX93_RS07700	COG4792	protein secretion
GPX93_RS07705	COG4789	Type iii secretion
GPX93_RS07815	COG0596	Alpha beta hydrolase
GPX93_RS07840	COG5492	domain, Protein
GPX93_RS07840	COG4932	domain protein
GPX93_RS07850	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
GPX93_RS07855	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
GPX93_RS07860	COG1737	Transcriptional regulator
GPX93_RS07865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPX93_RS07870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GPX93_RS07875	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GPX93_RS07880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPX93_RS07890	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GPX93_RS07895	COG1940	carbohydrate kinase activity
GPX93_RS07900	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPX93_RS07905	COG4409	exo-alpha-(2->6)-sialidase activity
GPX93_RS07930	COG5001	Diguanylate cyclase
GPX93_RS07940	COG0415	Belongs to the DNA photolyase family
GPX93_RS07950	COG4628	conserved protein (DUF2132)
GPX93_RS07955	COG3284	Transcriptional regulator
GPX93_RS07960	COG1012	belongs to the aldehyde dehydrogenase family
GPX93_RS07965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX93_RS07965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX93_RS07965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX93_RS07970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX93_RS07975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX93_RS07980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX93_RS07990	COG2207	Transcriptional regulator
GPX93_RS07995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX93_RS07995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX93_RS07995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX93_RS08000	COG1482	cell wall glycoprotein biosynthetic process
GPX93_RS08010	COG5002	protein histidine kinase activity
GPX93_RS08010	COG0784	Response regulator, receiver
GPX93_RS08020	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GPX93_RS08030	COG2885	chlorophyll binding
GPX93_RS08035	COG0823	Involved in the tonB-independent uptake of proteins
GPX93_RS08050	COG0811	peptide transport
GPX93_RS08055	COG0824	Thioesterase
GPX93_RS08060	COG3790	cyd operon protein YbgE
GPX93_RS08065	COG4890	Cyd operon protein YbgT
GPX93_RS08070	COG1294	oxidase, subunit
GPX93_RS08075	COG1271	oxidase subunit
GPX93_RS08080	COG2255	four-way junction helicase activity
GPX93_RS08085	COG0632	four-way junction helicase activity
GPX93_RS08090	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GPX93_RS08095	COG0215	cysteine-tRNA ligase activity
GPX93_RS08100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPX93_RS08105	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPX93_RS08110	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPX93_RS08120	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPX93_RS08130	COG1199	ATP-dependent helicase activity
GPX93_RS08135	COG0730	response to heat
GPX93_RS08140	COG3923	Primosomal replication protein n
GPX93_RS08150	COG0840	transmembrane signaling receptor activity
GPX93_RS08155	COG0708	Exodeoxyribonuclease III
GPX93_RS08160	COG4160	amino acid transport
GPX93_RS08165	COG4215	(ABC) transporter
GPX93_RS08185	COG1882	Formate acetyltransferase
GPX93_RS08195	COG0840	transmembrane signaling receptor activity
GPX93_RS08200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPX93_RS08210	COG3013	Belongs to the UPF0304 family
GPX93_RS08215	COG2766	serine protein kinase
GPX93_RS08220	COG2718	Belongs to the UPF0229 family
GPX93_RS08225	COG2719	SpoVR family
GPX93_RS08230	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GPX93_RS08240	COG1663	tetraacyldisaccharide 4'-kinase activity
GPX93_RS08245	COG1132	(ABC) transporter
GPX93_RS08250	COG0658	competence protein
GPX93_RS08250	COG2333	competence protein COMEC
GPX93_RS08265	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPX93_RS08270	COG1136	(ABC) transporter
GPX93_RS08275	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPX93_RS08285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPX93_RS08305	COG1252	NADH dehydrogenase
GPX93_RS08335	COG0537	adenosine 5'-monophosphoramidase activity
GPX93_RS08350	COG2186	Transcriptional regulator
GPX93_RS08355	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPX93_RS08360	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GPX93_RS08365	COG1674	ftsk spoiiie
GPX93_RS08380	COG0686	Belongs to the AlaDH PNT family
GPX93_RS08390	COG0583	DNA-binding transcription factor activity
GPX93_RS08405	COG0284	orotidine-5'-phosphate decarboxylase activity
GPX93_RS08410	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GPX93_RS08415	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GPX93_RS08420	COG0776	regulation of translation
GPX93_RS08425	COG0539	negative regulation of cytoplasmic translation
GPX93_RS08430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GPX93_RS08435	COG1555	photosystem II stabilization
GPX93_RS08440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPX93_RS08445	COG0776	regulation of translation
GPX93_RS08450	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GPX93_RS08455	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPX93_RS08465	COG0544	peptidyl-prolyl cis-trans isomerase activity
GPX93_RS08475	COG4191	Histidine kinase
GPX93_RS08485	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GPX93_RS08490	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GPX93_RS08495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPX93_RS08500	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GPX93_RS08515	COG5001	Diguanylate cyclase
GPX93_RS08515	COG3300	MHYT domain
GPX93_RS08525	COG4589	Belongs to the CDS family
GPX93_RS08560	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPX93_RS08570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPX93_RS08590	COG0243	molybdopterin cofactor binding
GPX93_RS08595	COG3005	denitrification pathway
GPX93_RS08600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPX93_RS08610	COG2951	lytic endotransglycosylase activity
GPX93_RS08615	COG3100	YcgL domain-containing protein
GPX93_RS08620	COG0850	regulation of cytokinetic process
GPX93_RS08625	COG2894	cell division
GPX93_RS08630	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GPX93_RS08635	COG3015	lipoprotein NlpE involved in copper resistance
GPX93_RS08660	COG0840	transmembrane signaling receptor activity
GPX93_RS08665	COG1396	sequence-specific DNA binding
GPX93_RS08670	COG3135	benzoate transporter
GPX93_RS08680	COG1441	menaquinone biosynthetic process
GPX93_RS08690	COG0596	Alpha beta hydrolase
GPX93_RS08695	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GPX93_RS08700	COG1169	isochorismate synthase
GPX93_RS08705	COG0436	Aminotransferase
GPX93_RS08710	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GPX93_RS08715	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GPX93_RS08730	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GPX93_RS08735	COG0318	PFAM AMP-dependent synthetase and ligase
GPX93_RS08755	COG1214	PFAM Peptidase M22, glycoprotease
GPX93_RS08760	COG1199	ATP-dependent helicase activity
GPX93_RS08770	COG0788	formyltetrahydrofolate deformylase activity
GPX93_RS08775	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPX93_RS08775	COG1902	pentaerythritol trinitrate reductase activity
GPX93_RS08780	COG0616	signal peptide processing
GPX93_RS08785	COG0252	asparaginase activity
GPX93_RS08790	COG3139	Protein of unknown function (DUF1315)
GPX93_RS08800	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPX93_RS08805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPX93_RS08810	COG0676	glucose-6-phosphate 1-epimerase activity
GPX93_RS08820	COG2226	methyltransferase
GPX93_RS08835	COG0784	Response regulator, receiver
GPX93_RS08835	COG0835	chemotaxis
GPX93_RS08840	COG1940	carbohydrate kinase activity
GPX93_RS08850	COG4667	esterase of the alpha-beta hydrolase superfamily
GPX93_RS08865	COG0733	neurotransmitter:sodium symporter activity
GPX93_RS08875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX93_RS08875	COG1263	PTS System
GPX93_RS08880	COG0084	hydrolase, TatD family'
GPX93_RS08890	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPX93_RS08895	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPX93_RS08900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPX93_RS08905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPX93_RS08910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPX93_RS08915	COG1028	Short-chain dehydrogenase reductase Sdr
GPX93_RS08920	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GPX93_RS08925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPX93_RS08930	COG0416	fatty acid biosynthetic process
GPX93_RS08935	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GPX93_RS08940	COG1399	metal-binding, possibly nucleic acid-binding protein
GPX93_RS08945	COG0424	maF-like protein
GPX93_RS08950	COG0564	pseudouridine synthase activity
GPX93_RS08955	COG1530	ribonuclease E activity
GPX93_RS08960	COG0659	secondary active sulfate transmembrane transporter activity
GPX93_RS08970	COG1454	alcohol dehydrogenase
GPX93_RS08970	COG1012	belongs to the aldehyde dehydrogenase family
GPX93_RS08975	COG2095	MarC family integral membrane protein
GPX93_RS08980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPX93_RS08985	COG1757	Na H antiporter
GPX93_RS08995	COG3081	Nucleoid-associated protein
GPX93_RS09005	COG3083	sulfuric ester hydrolase activity
GPX93_RS09020	COG0123	including yeast histone deacetylase and acetoin utilization protein
GPX93_RS09025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPX93_RS09030	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GPX93_RS09050	COG2853	Lipoprotein
GPX93_RS09060	COG4235	cytochrome complex assembly
GPX93_RS09060	COG3088	subunit of a heme lyase
GPX93_RS09065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPX93_RS09070	COG1138	Cytochrome C-type biogenesis protein
GPX93_RS09075	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GPX93_RS09085	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPX93_RS09090	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPX93_RS09095	COG4133	protoheme IX ABC transporter activity
GPX93_RS09105	COG0835	chemotaxis
GPX93_RS09115	COG1192	Involved in chromosome partitioning
GPX93_RS09120	COG2201	protein-glutamate methylesterase activity
GPX93_RS09125	COG0643	Histidine kinase
GPX93_RS09125	COG2198	Histidine kinase
GPX93_RS09130	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GPX93_RS09145	COG0455	bacterial-type flagellum organization
GPX93_RS09160	COG2062	phosphohistidine phosphatase, SixA
GPX93_RS09165	COG1025	Belongs to the peptidase M16 family
GPX93_RS09175	COG0018	arginyl-trna synthetase
GPX93_RS09195	COG1918	ferrous iron import across plasma membrane
GPX93_RS09200	COG4977	sequence-specific DNA binding
GPX93_RS09205	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GPX93_RS09210	COG1121	(ABC) transporter
GPX93_RS09215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPX93_RS09225	COG0045	succinate-CoA ligase (ADP-forming) activity
GPX93_RS09230	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPX93_RS09235	COG0567	Dehydrogenase, E1 component
GPX93_RS09245	COG1053	succinate dehydrogenase
GPX93_RS09250	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GPX93_RS09255	COG2009	succinate dehydrogenase
GPX93_RS09260	COG0372	Belongs to the citrate synthase family
GPX93_RS09265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPX93_RS09275	COG0033	Phosphoglucomutase
GPX93_RS09280	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GPX93_RS09285	COG0596	Alpha beta hydrolase
GPX93_RS09300	COG1346	cytolysis
GPX93_RS09310	COG0583	DNA-binding transcription factor activity
GPX93_RS09320	COG0735	belongs to the Fur family
GPX93_RS09325	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPX93_RS09330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPX93_RS09335	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPX93_RS09340	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GPX93_RS09340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPX93_RS09345	COG0431	NADPH-dependent FMN reductase
GPX93_RS09355	COG3101	peptidyl-lysine hydroxylation
GPX93_RS09360	COG2860	membrane
GPX93_RS09365	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPX93_RS09370	COG2890	protein-(glutamine-N5) methyltransferase activity
GPX93_RS09385	COG1684	flagellar biosynthetic protein fliR
GPX93_RS09390	COG1987	bacterial-type flagellum assembly
GPX93_RS09415	COG1580	Controls the rotational direction of flagella during chemotaxis
GPX93_RS09440	COG1317	bacterial-type flagellum organization
GPX93_RS09445	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPX93_RS09455	COG1677	Flagellar hook-basal body complex protein FliE
GPX93_RS09460	COG2204	response regulator
GPX93_RS09465	COG4191	Histidine kinase
GPX93_RS09470	COG2204	response regulator
GPX93_RS09475	COG1516	flagellar protein fliS
GPX93_RS09485	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPX93_RS09490	COG1334	flagellar protein FlaG
GPX93_RS09495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPX93_RS09500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPX93_RS09505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPX93_RS09510	COG2837	iron assimilation
GPX93_RS09530	COG1393	Belongs to the ArsC family
GPX93_RS09535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPX93_RS09540	COG1876	peptidase activity
GPX93_RS09550	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GPX93_RS09555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPX93_RS09565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPX93_RS09585	COG4783	chaperone-mediated protein folding
GPX93_RS09590	COG1393	Belongs to the ArsC family
GPX93_RS09610	COG2233	PERMEase
GPX93_RS09615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPX93_RS09620	COG0737	Belongs to the 5'-nucleotidase family
GPX93_RS09625	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GPX93_RS09630	COG2912	Transglutaminase-like superfamily
GPX93_RS09635	COG3094	Invasion gene expression up-regulator, SirB
GPX93_RS09640	COG2890	protein-(glutamine-N5) methyltransferase activity
GPX93_RS09645	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPX93_RS09650	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GPX93_RS09655	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GPX93_RS09660	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPX93_RS09665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPX93_RS09670	COG0193	aminoacyl-tRNA hydrolase activity
GPX93_RS09675	COG0012	GTP binding
GPX93_RS09760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPX93_RS09765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPX93_RS09785	COG1705	Flagellar rod assembly protein muramidase FlgJ
GPX93_RS09785	COG3951	Flagellar rod assembly protein muramidase FlgJ
GPX93_RS09790	COG1706	bacterial-type flagellum-dependent cell motility
GPX93_RS09795	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GPX93_RS09800	COG4786	Flagellar basal body rod
GPX93_RS09805	COG4787	bacterial-type flagellum-dependent cell motility
GPX93_RS09810	COG1749	Flagellar hook protein flgE
GPX93_RS09815	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPX93_RS09820	COG1558	bacterial-type flagellum-dependent cell motility
GPX93_RS09825	COG1815	bacterial-type flagellum-dependent cell motility
GPX93_RS09830	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPX93_RS09835	COG0835	chemotaxis
GPX93_RS09835	COG0784	Response regulator, receiver
GPX93_RS09870	COG3433	isochorismatase activity
GPX93_RS09870	COG2226	methyltransferase
GPX93_RS09870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPX93_RS09875	COG2375	cellular response to nickel ion
GPX93_RS09880	COG1629	transport
GPX93_RS09880	COG4774	siderophore transport
GPX93_RS09895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPX93_RS09900	COG2217	Heavy metal translocating P-type atpase
GPX93_RS09900	COG2608	mercury ion transmembrane transporter activity
GPX93_RS09915	COG3735	TraB family
GPX93_RS09930	COG2840	Smr protein MutS2
GPX93_RS09935	COG1187	pseudouridine synthase activity
GPX93_RS09940	COG3706	GGDEF domain
GPX93_RS09945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPX93_RS09950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GPX93_RS09955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPX93_RS09960	COG0121	glutamine amidotransferase
GPX93_RS09965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPX93_RS09970	COG1960	acyl-CoA dehydrogenase activity
GPX93_RS09980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPX93_RS09985	COG0328	RNA-DNA hybrid ribonuclease activity
GPX93_RS09990	COG2226	methyltransferase
GPX93_RS09995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPX93_RS10000	COG1388	LysM domain
GPX93_RS10000	COG0741	lytic transglycosylase activity
GPX93_RS10010	COG0347	Belongs to the P(II) protein family
GPX93_RS10015	COG3479	Phenolic acid decarboxylase
GPX93_RS10025	COG0037	tRNA processing
GPX93_RS10030	COG0825	malonyl-CoA metabolic process
GPX93_RS10035	COG0587	DNA-directed DNA polymerase activity
GPX93_RS10040	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPX93_RS10045	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPX93_RS10050	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPX93_RS10055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPX93_RS10060	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPX93_RS10065	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GPX93_RS10075	COG0750	zinc metalloprotease
GPX93_RS10080	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GPX93_RS10085	COG0575	Belongs to the CDS family
GPX93_RS10090	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPX93_RS10095	COG0233	cytoplasmic translational termination
GPX93_RS10100	COG0528	UMP kinase activity
GPX93_RS10105	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPX93_RS10110	COG0052	Belongs to the universal ribosomal protein uS2 family
GPX93_RS10115	COG0024	Methionine aminopeptidase
GPX93_RS10120	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GPX93_RS10130	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GPX93_RS10135	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GPX93_RS10140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPX93_RS10145	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GPX93_RS10160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPX93_RS10160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPX93_RS10165	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPX93_RS10170	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPX93_RS10175	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPX93_RS10190	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GPX93_RS10195	COG2252	PERMEase
GPX93_RS10200	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPX93_RS10205	COG0189	ligase activity
GPX93_RS10205	COG4067	protein conserved in archaea
GPX93_RS10210	COG0189	ligase activity
GPX93_RS10220	COG0733	neurotransmitter:sodium symporter activity
GPX93_RS10225	COG3706	GGDEF domain
GPX93_RS10235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPX93_RS10245	COG1477	protein flavinylation
GPX93_RS10250	COG2871	sodium ion transport
GPX93_RS10255	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPX93_RS10260	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPX93_RS10265	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPX93_RS10270	COG1805	sodium ion transport
GPX93_RS10275	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPX93_RS10280	COG0271	Belongs to the BolA IbaG family
GPX93_RS10285	COG2813	Specifically methylates the guanine in position
GPX93_RS10295	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPX93_RS10305	COG2211	Major facilitator Superfamily
GPX93_RS10315	COG1595	DNA-templated transcription, initiation
GPX93_RS10325	COG3248	Nucleoside-binding outer membrane protein
GPX93_RS10330	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPX93_RS10335	COG0693	protein deglycase activity
GPX93_RS10340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPX93_RS10345	COG2166	iron-sulfur cluster assembly
GPX93_RS10350	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GPX93_RS10355	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GPX93_RS10365	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPX93_RS10365	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPX93_RS10375	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GPX93_RS10380	COG1074	ATP-dependent DNA helicase activity
GPX93_RS10385	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GPX93_RS10400	COG3141	response to X-ray
GPX93_RS10405	COG2171	N-acyltransferase activity
GPX93_RS10415	COG0456	acetyltransferase
GPX93_RS10420	COG0569	domain protein
GPX93_RS10420	COG0189	ligase activity
GPX93_RS10435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPX93_RS10440	COG1609	Transcriptional regulator
GPX93_RS10445	COG3250	beta-galactosidase activity
GPX93_RS10460	COG1022	Amp-dependent synthetase and ligase
GPX93_RS10465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPX93_RS10470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPX93_RS10480	COG0560	Phosphoserine phosphatase
GPX93_RS10490	COG0813	purine-nucleoside phosphorylase activity
GPX93_RS10495	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPX93_RS10500	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GPX93_RS10505	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPX93_RS10515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPX93_RS10520	COG0084	hydrolase, TatD family'
GPX93_RS10535	COG1115	amino acid carrier protein
GPX93_RS10550	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPX93_RS10555	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GPX93_RS10560	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
GPX93_RS10565	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPX93_RS10570	COG0083	homoserine kinase activity
GPX93_RS10590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPX93_RS10600	COG0745	RESPONSE REGULATOR receiver
GPX93_RS10605	COG2198	Histidine kinase
GPX93_RS10605	COG0784	Response regulator, receiver
GPX93_RS10605	COG5002	protein histidine kinase activity
GPX93_RS10610	COG5001	Diguanylate cyclase
GPX93_RS10610	COG4251	negative regulation of phosphorylation
GPX93_RS10610	COG3706	GGDEF domain
GPX93_RS10610	COG2203	Gaf domain
GPX93_RS10615	COG1242	4 iron, 4 sulfur cluster binding
GPX93_RS10620	COG0069	glutamate synthase activity
GPX93_RS10620	COG0070	glutamate synthase
GPX93_RS10620	COG0067	glutamate synthase
GPX93_RS10630	COG0067	glutamate synthase
GPX93_RS10630	COG0070	glutamate synthase
GPX93_RS10630	COG0069	glutamate synthase activity
GPX93_RS10635	COG0493	'glutamate synthase
GPX93_RS10645	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPX93_RS10655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPX93_RS10660	COG2860	membrane
GPX93_RS10665	COG0583	DNA-binding transcription factor activity
GPX93_RS10670	COG0730	response to heat
GPX93_RS10685	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GPX93_RS10690	COG0505	Belongs to the CarA family
GPX93_RS10700	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GPX93_RS10705	COG0494	nUDIX hydrolase
GPX93_RS10710	COG0653	protein targeting
GPX93_RS10720	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GPX93_RS10725	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPX93_RS10730	COG0849	cell division
GPX93_RS10735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GPX93_RS10740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPX93_RS10745	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPX93_RS10750	COG0772	Belongs to the SEDS family
GPX93_RS10755	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPX93_RS10760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPX93_RS10765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GPX93_RS10770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPX93_RS10775	COG0768	penicillin binding
GPX93_RS10780	COG3116	cell division
GPX93_RS10785	COG0275	rRNA processing
GPX93_RS10795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPX93_RS10800	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPX93_RS10805	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GPX93_RS10810	COG2186	Transcriptional regulator
GPX93_RS10815	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GPX93_RS10820	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPX93_RS10825	COG4974	Belongs to the 'phage' integrase family
GPX93_RS10830	COG0716	FMN binding
GPX93_RS10850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPX93_RS10855	COG1459	type II secretion system
GPX93_RS10865	COG0237	dephospho-CoA kinase activity
GPX93_RS10870	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GPX93_RS10875	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GPX93_RS10880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPX93_RS10885	COG0187	DNA topoisomerase II activity
GPX93_RS10890	COG3150	esterase
GPX93_RS10900	COG3151	Protein conserved in bacteria
GPX93_RS10905	COG0494	nUDIX hydrolase
GPX93_RS10910	COG1538	Outer membrane efflux protein
GPX93_RS10915	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GPX93_RS10915	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GPX93_RS10920	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GPX93_RS10925	COG0840	transmembrane signaling receptor activity
GPX93_RS10930	COG3025	triphosphatase activity
GPX93_RS10935	COG1392	Phosphate transport regulator
GPX93_RS10940	COG0306	phosphate transporter
GPX93_RS10945	COG4991	sh3 domain protein
GPX93_RS10955	COG3267	Type II secretory pathway component ExeA
GPX93_RS10955	COG3409	Peptidoglycan-binding domain 1 protein
GPX93_RS10960	COG0617	tRNA 3'-terminal CCA addition
GPX93_RS10965	COG0148	phosphopyruvate hydratase activity
GPX93_RS10970	COG0504	CTP synthase activity
GPX93_RS10975	COG3956	TIGRFAM MazG family protein
GPX93_RS10980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPX93_RS10985	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPX93_RS10995	COG5001	Diguanylate cyclase
GPX93_RS11010	COG0736	holo-[acyl-carrier-protein] synthase activity
GPX93_RS11015	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GPX93_RS11020	COG1381	Involved in DNA repair and RecF pathway recombination
GPX93_RS11025	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPX93_RS11030	COG0571	ribonuclease III activity
GPX93_RS11035	COG0681	Belongs to the peptidase S26 family
GPX93_RS11040	COG0481	GTPase activity
GPX93_RS11045	COG3086	response to oxidative stress
GPX93_RS11050	COG3026	antisigma factor binding
GPX93_RS11060	COG1595	DNA-templated transcription, initiation
GPX93_RS11065	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GPX93_RS11075	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GPX93_RS11080	COG0354	folic acid binding
GPX93_RS11090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPX93_RS11095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPX93_RS11105	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPX93_RS11115	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPX93_RS11120	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GPX93_RS11125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPX93_RS11130	COG0440	acetolactate synthase activity
GPX93_RS11135	COG0028	Belongs to the TPP enzyme family
GPX93_RS11140	COG1022	Amp-dependent synthetase and ligase
GPX93_RS11145	COG0583	DNA-binding transcription factor activity
GPX93_RS11165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPX93_RS11170	COG0473	3-isopropylmalate dehydrogenase activity
GPX93_RS11175	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPX93_RS11180	COG0066	3-isopropylmalate dehydratase activity
GPX93_RS11225	COG3437	response regulator, receiver
GPX93_RS11240	COG0795	lipopolysaccharide-transporting ATPase activity
GPX93_RS11245	COG0795	lipopolysaccharide-transporting ATPase activity
GPX93_RS11250	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPX93_RS11255	COG2927	DNA polymerase III (CHI subunit)
GPX93_RS11260	COG0525	valine-tRNA ligase activity
GPX93_RS11270	COG4269	membrane
GPX93_RS11275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPX93_RS11280	COG0564	pseudouridine synthase activity
GPX93_RS11285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GPX93_RS11290	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GPX93_RS11295	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPX93_RS11300	COG0540	Belongs to the ATCase OTCase family
GPX93_RS11305	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GPX93_RS11310	COG0251	oxidation-reduction process
GPX93_RS11315	COG0204	Acyl-transferase
GPX93_RS11320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPX93_RS11325	COG5007	Belongs to the BolA IbaG family
GPX93_RS11335	COG2854	intermembrane phospholipid transfer
GPX93_RS11340	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPX93_RS11345	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GPX93_RS11350	COG1127	ABC transporter
GPX93_RS11360	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GPX93_RS11360	COG0517	IMP dehydrogenase activity
GPX93_RS11375	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GPX93_RS11380	COG1137	ATPase activity
GPX93_RS11390	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPX93_RS11395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX93_RS11405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX93_RS11410	COG2239	Acts as a magnesium transporter
GPX93_RS11415	COG0312	modulator of DNA gyrase
GPX93_RS11420	COG3028	Belongs to the UPF0307 family
GPX93_RS11425	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GPX93_RS11430	COG1178	ABC-type Fe3 transport system permease component
GPX93_RS11435	COG4143	(ABC) transporter
GPX93_RS11440	COG0163	prenyltransferase activity
GPX93_RS11445	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPX93_RS11450	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GPX93_RS11455	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GPX93_RS11460	COG2105	PFAM AIG2 family protein
GPX93_RS11470	COG0729	surface antigen
GPX93_RS11475	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPX93_RS11480	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GPX93_RS11495	COG1136	(ABC) transporter
GPX93_RS11495	COG0577	efflux transmembrane transporter activity
GPX93_RS11515	COG0529	Catalyzes the synthesis of activated sulfate
GPX93_RS11520	COG2895	sulfate adenylyltransferase (ATP) activity
GPX93_RS11525	COG0175	sulfate reduction
GPX93_RS11530	COG1648	precorrin-2 dehydrogenase activity
GPX93_RS11530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPX93_RS11535	COG0737	Belongs to the 5'-nucleotidase family
GPX93_RS11545	COG0513	Belongs to the DEAD box helicase family
GPX93_RS11550	COG2153	protein acetylation
GPX93_RS11555	COG0697	spore germination
GPX93_RS11560	COG3266	domain, Protein
GPX93_RS11560	COG3061	Opacity-associated protein A
GPX93_RS11565	COG0545	Peptidyl-prolyl cis-trans isomerase
GPX93_RS11575	COG0203	ribosomal protein L17
GPX93_RS11580	COG0202	RNA polymerase activity
GPX93_RS11585	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GPX93_RS11590	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPX93_RS11595	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPX93_RS11605	COG0201	protein transport
GPX93_RS11610	COG0200	Binds to the 23S rRNA
GPX93_RS11615	COG1841	ribosomal large subunit assembly
GPX93_RS11620	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GPX93_RS11625	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GPX93_RS11630	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPX93_RS11635	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPX93_RS11640	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPX93_RS11645	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPX93_RS11650	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPX93_RS11655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPX93_RS11660	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GPX93_RS11665	COG0255	Belongs to the universal ribosomal protein uL29 family
GPX93_RS11670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GPX93_RS11675	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPX93_RS11680	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPX93_RS11685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPX93_RS11690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPX93_RS11695	COG0089	rRNA binding
GPX93_RS11700	COG0088	Forms part of the polypeptide exit tunnel
GPX93_RS11705	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPX93_RS11710	COG0051	transcription antitermination factor activity, RNA binding
GPX93_RS11715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPX93_RS11720	COG0557	exoribonuclease II activity
GPX93_RS11725	COG3083	sulfuric ester hydrolase activity
GPX93_RS11730	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GPX93_RS11735	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPX93_RS11745	COG1047	Peptidyl-prolyl cis-trans
GPX93_RS11760	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPX93_RS11765	COG0488	(ABC) transporter
GPX93_RS11775	COG0429	hydrolase of the alpha beta-hydrolase fold
GPX93_RS11785	COG3954	Phosphoribulokinase
GPX93_RS11790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPX93_RS11810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPX93_RS11820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPX93_RS11835	COG0180	Tryptophanyl-tRNA synthetase
GPX93_RS11840	COG0546	phosphoglycolate phosphatase activity
GPX93_RS11845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GPX93_RS11850	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GPX93_RS11860	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GPX93_RS11865	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GPX93_RS11895	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GPX93_RS11905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPX93_RS11905	COG0678	peroxiredoxin activity
GPX93_RS11910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPX93_RS11920	COG0165	Argininosuccinate lyase
GPX93_RS11925	COG0137	argininosuccinate synthase activity
GPX93_RS11930	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPX93_RS11935	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPX93_RS11940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPX93_RS11945	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GPX93_RS11955	COG1045	serine acetyltransferase
GPX93_RS11960	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GPX93_RS11965	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GPX93_RS11970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPX93_RS11975	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GPX93_RS11980	COG1053	succinate dehydrogenase
GPX93_RS11985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPX93_RS11990	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPX93_RS11995	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPX93_RS12000	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPX93_RS12005	COG1509	lysine 2,3-aminomutase activity
GPX93_RS12025	COG0459	protein refolding
GPX93_RS12030	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPX93_RS12055	COG0149	triose-phosphate isomerase activity
GPX93_RS12065	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPX93_RS12070	COG1575	Belongs to the MenA family. Type 1 subfamily
GPX93_RS12075	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GPX93_RS12080	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GPX93_RS12085	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPX93_RS12090	COG1609	Transcriptional regulator
GPX93_RS12095	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPX93_RS12100	COG0254	rRNA binding
GPX93_RS12105	COG0281	malic enzyme
GPX93_RS12110	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
GPX93_RS12115	COG0626	cystathionine gamma-synthase activity
GPX93_RS12120	COG0527	aspartate kinase activity
GPX93_RS12120	COG0460	homoserine dehydrogenase
GPX93_RS12125	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GPX93_RS12130	COG3074	FtsZ-dependent cytokinesis
GPX93_RS12135	COG1494	fructose-1,6-bisphosphatase
GPX93_RS12140	COG0205	6-phosphofructokinase activity
GPX93_RS12145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPX93_RS12155	COG0745	RESPONSE REGULATOR receiver
GPX93_RS12160	COG2205	protein histidine kinase activity
GPX93_RS12170	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GPX93_RS12175	COG3030	protein affecting phage T7 exclusion by the F plasmid
GPX93_RS12180	COG3706	GGDEF domain
GPX93_RS12185	COG1027	Aspartate ammonia-lyase
GPX93_RS12190	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPX93_RS12200	COG4232	protein-disulfide reductase activity
GPX93_RS12210	COG3263	regulation of cellular component size
GPX93_RS12220	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPX93_RS12225	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPX93_RS12230	COG0194	GDP metabolic process
GPX93_RS12235	COG1758	RNA polymerase activity
GPX93_RS12240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPX93_RS12245	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPX93_RS12250	COG2233	PERMEase
GPX93_RS12260	COG0745	RESPONSE REGULATOR receiver
GPX93_RS12265	COG2199	diguanylate cyclase activity
GPX93_RS12270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPX93_RS12275	COG2183	response to ionizing radiation
GPX93_RS12285	COG0596	Alpha beta hydrolase
GPX93_RS12290	COG1040	competence protein
GPX93_RS12295	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GPX93_RS12295	COG0316	Belongs to the HesB IscA family
GPX93_RS12300	COG0494	nUDIX hydrolase
GPX93_RS12305	COG1218	3'(2'),5'-bisphosphate nucleotidase
GPX93_RS12315	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPX93_RS12320	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPX93_RS12325	COG3156	type II secretion system protein K
GPX93_RS12330	COG4795	General secretion pathway protein
GPX93_RS12335	COG2165	general secretion pathway protein
GPX93_RS12340	COG2165	general secretion pathway protein
GPX93_RS12345	COG2165	general secretion pathway protein
GPX93_RS12350	COG1459	type II secretion system
GPX93_RS12355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPX93_RS12365	COG3031	protein transport across the cell outer membrane
GPX93_RS12370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GPX93_RS12375	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPX93_RS12380	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GPX93_RS12390	COG0456	acetyltransferase
GPX93_RS12395	COG1490	D-aminoacyl-tRNA deacylase activity
GPX93_RS12405	COG1660	Displays ATPase and GTPase activities
GPX93_RS12420	COG0174	glutamine synthetase
GPX93_RS12430	COG3852	Histidine kinase
GPX93_RS12440	COG3300	MHYT domain
GPX93_RS12440	COG5001	Diguanylate cyclase
GPX93_RS12445	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPX93_RS12510	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GPX93_RS12515	COG1404	Belongs to the peptidase S8 family
GPX93_RS12525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPX93_RS12530	COG1943	Transposase
GPX93_RS12545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPX93_RS12550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPX93_RS12555	COG2177	Part of the ABC transporter FtsEX involved in
GPX93_RS12560	COG2884	Cell division ATP-binding protein ftsE
GPX93_RS12565	COG0552	protein localization to endoplasmic reticulum
GPX93_RS12570	COG0742	ribosomal rna small subunit methyltransferase
GPX93_RS12600	COG0783	Belongs to the Dps family
GPX93_RS12605	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPX93_RS12610	COG1280	lysine exporter protein (LysE YggA)
GPX93_RS12615	COG2267	carboxylic ester hydrolase activity
GPX93_RS12620	COG0561	phosphatase activity
GPX93_RS12635	COG2200	EAL domain
GPX93_RS12635	COG2199	diguanylate cyclase activity
GPX93_RS12635	COG3287	FIST C domain
GPX93_RS12640	COG1011	Hydrolase
GPX93_RS12645	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GPX93_RS12655	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GPX93_RS12660	COG0019	diaminopimelate decarboxylase activity
GPX93_RS12670	COG1965	Belongs to the frataxin family
GPX93_RS12675	COG3072	Adenylate cyclase
GPX93_RS12685	COG0181	hydroxymethylbilane synthase activity
GPX93_RS12690	COG1587	Uroporphyrinogen-III synthase
GPX93_RS12695	COG2959	enzyme of heme biosynthesis
GPX93_RS12700	COG3071	HemY protein
GPX93_RS12705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPX93_RS12715	COG3078	GTPase activator activity
GPX93_RS12730	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GPX93_RS12735	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPX93_RS12735	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPX93_RS12750	COG0084	hydrolase, TatD family'
GPX93_RS12755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPX93_RS12765	COG0840	transmembrane signaling receptor activity
GPX93_RS12770	COG1580	Controls the rotational direction of flagella during chemotaxis
GPX93_RS12780	COG3161	chorismate lyase activity
GPX93_RS12785	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GPX93_RS12790	COG2937	Belongs to the GPAT DAPAT family
GPX93_RS12795	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPX93_RS12805	COG0534	Mate efflux family protein
GPX93_RS12810	COG0805	protein transport
GPX93_RS12815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPX93_RS12820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPX93_RS12825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GPX93_RS12835	COG2226	methyltransferase
GPX93_RS12840	COG1322	Protein conserved in bacteria
GPX93_RS12850	COG2081	HI0933 family
GPX93_RS12860	COG1528	Iron-storage protein
GPX93_RS12870	COG0589	response to stress
GPX93_RS12875	COG0697	spore germination
GPX93_RS12885	COG0742	ribosomal rna small subunit methyltransferase
GPX93_RS12890	COG5002	protein histidine kinase activity
GPX93_RS12890	COG5001	Diguanylate cyclase
GPX93_RS12895	COG1522	sequence-specific DNA binding
GPX93_RS12915	COG0006	proline dipeptidase activity
GPX93_RS12915	COG0006	proline dipeptidase activity
GPX93_RS12920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPX93_RS12925	COG2022	thiamine diphosphate biosynthetic process
GPX93_RS12930	COG2104	thiamine diphosphate biosynthetic process
GPX93_RS12935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPX93_RS12945	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GPX93_RS12950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPX93_RS12990	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPX93_RS13000	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPX93_RS13005	COG0408	coproporphyrinogen oxidase activity
GPX93_RS13010	COG0009	L-threonylcarbamoyladenylate synthase
GPX93_RS13015	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPX93_RS13020	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPX93_RS13025	COG0551	DNA topoisomerase type I activity
GPX93_RS13030	COG2922	Belongs to the Smg family
GPX93_RS13035	COG0758	DNA mediated transformation
GPX93_RS13040	COG1652	LysM domain
GPX93_RS13045	COG0242	peptide deformylase activity
GPX93_RS13050	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPX93_RS13055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPX93_RS13055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPX93_RS13060	COG0569	domain protein
GPX93_RS13065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPX93_RS13075	COG1272	protein, Hemolysin III
GPX93_RS13080	COG4326	sporulation control protein
GPX93_RS13090	COG3084	Protein conserved in bacteria
GPX93_RS13100	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPX93_RS13105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPX93_RS13110	COG0204	Acyl-transferase
GPX93_RS13115	COG0606	chelatase, subunit chli
GPX93_RS13130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPX93_RS13135	COG0129	dihydroxy-acid dehydratase activity
GPX93_RS13145	COG0604	alcohol dehydrogenase
GPX93_RS13155	COG0425	Belongs to the sulfur carrier protein TusA family
GPX93_RS13165	COG2119	membrane
GPX93_RS13170	COG0752	glycyl-tRNA synthetase alpha subunit
GPX93_RS13175	COG0751	glycine-tRNA ligase activity
GPX93_RS13180	COG3977	Valine--pyruvate aminotransferase
GPX93_RS13185	COG0071	Belongs to the small heat shock protein (HSP20) family
GPX93_RS13200	COG0187	DNA topoisomerase II activity
GPX93_RS13205	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPX93_RS13210	COG0592	DNA-directed DNA polymerase activity
GPX93_RS13215	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPX93_RS13230	COG1126	abc transporter atp-binding protein
GPX93_RS13235	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GPX93_RS13240	COG0594	ribonuclease P activity
GPX93_RS13245	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GPX93_RS13250	COG0706	membrane insertase activity
GPX93_RS13255	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPX93_RS13260	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPX93_RS13270	COG0445	tRNA wobble uridine modification
GPX93_RS13275	COG0357	Ribosomal RNA small subunit methyltransferase G
GPX93_RS13280	COG1192	Involved in chromosome partitioning
GPX93_RS13285	COG1475	DNA binding
GPX93_RS13290	COG3312	ion transport
GPX93_RS13295	COG0356	it plays a direct role in the translocation of protons across the membrane
GPX93_RS13305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GPX93_RS13310	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPX93_RS13315	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPX93_RS13320	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPX93_RS13325	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPX93_RS13330	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GPX93_RS13340	COG2814	Major facilitator Superfamily
GPX93_RS13345	COG0583	DNA-binding transcription factor activity
GPX93_RS13350	COG0183	Belongs to the thiolase family
GPX93_RS13355	COG1024	Enoyl-CoA hydratase
GPX93_RS13355	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPX93_RS13360	COG1739	Uncharacterized protein family UPF0029
GPX93_RS13365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPX93_RS13370	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GPX93_RS13485	COG3041	Addiction module toxin RelE StbE family
GPX93_RS13610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GPX93_RS13650	COG0384	phenazine biosynthesis protein PhzF
GPX93_RS13660	COG1619	proteins homologs of microcin C7 resistance protein MccF
GPX93_RS13670	COG0456	acetyltransferase
GPX93_RS13790	COG0346	lactoylglutathione lyase activity
GPX93_RS13825	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GPX93_RS13915	COG3040	lipid binding
GPX93_RS13960	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPX93_RS13995	COG0494	nUDIX hydrolase
GPX93_RS14060	COG0456	acetyltransferase
GPX93_RS14190	COG0346	lactoylglutathione lyase activity
GPX93_RS14235	COG0384	phenazine biosynthesis protein PhzF
GPX93_RS14275	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GPX93_RS14280	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GPX93_RS14290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPX93_RS14295	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GPX93_RS14305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPX93_RS14310	COG0509	glycine decarboxylation via glycine cleavage system
GPX93_RS14315	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPX93_RS14315	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPX93_RS14335	COG1686	Belongs to the peptidase S11 family
GPX93_RS14355	COG5002	protein histidine kinase activity
GPX93_RS14360	COG0745	RESPONSE REGULATOR receiver
GPX93_RS14410	COG0561	phosphatase activity
GPX93_RS14415	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GPX93_RS14420	COG3623	hexulose-6-phosphate isomerase
GPX93_RS14430	COG0745	RESPONSE REGULATOR receiver
GPX93_RS14450	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPX93_RS14470	COG4604	ABC transporter, ATP-binding protein
GPX93_RS14475	COG4605	iron ion homeostasis
GPX93_RS14480	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPX93_RS14500	COG4412	M6 family metalloprotease domain protein
GPX93_RS14500	COG3291	Pkd domain containing protein
GPX93_RS14505	COG5380	lipid catabolic process
GPX93_RS14510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPX93_RS14515	COG0840	transmembrane signaling receptor activity
GPX93_RS14525	COG3240	lipase activity
GPX93_RS14530	COG3706	GGDEF domain
GPX93_RS14540	COG2814	Major facilitator Superfamily
GPX93_RS14545	COG1757	Na H antiporter
GPX93_RS14555	COG4191	Histidine kinase
GPX93_RS14555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX93_RS14560	COG0784	Response regulator, receiver
GPX93_RS14560	COG3437	response regulator, receiver
GPX93_RS14565	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPX93_RS14570	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GPX93_RS14575	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPX93_RS14580	COG0513	Belongs to the DEAD box helicase family
GPX93_RS14715	COG4695	Portal protein
GPX93_RS14790	COG4974	Belongs to the 'phage' integrase family
GPX93_RS14800	COG0516	GMP reductase activity
GPX93_RS14810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPX93_RS14820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPX93_RS14825	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPX93_RS14825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GPX93_RS14850	COG3036	rescue of stalled ribosome
GPX93_RS14855	COG1278	Cold shock
GPX93_RS14860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPX93_RS14860	COG1017	nitric oxide dioxygenase activity
GPX93_RS14865	COG3604	Transcriptional regulator
GPX93_RS14875	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPX93_RS14880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPX93_RS14895	COG0840	transmembrane signaling receptor activity
GPX93_RS14900	COG0714	Associated with various cellular activities
GPX93_RS14920	COG2304	oxidoreductase activity
GPX93_RS14935	COG1278	Cold shock
GPX93_RS14940	COG5002	protein histidine kinase activity
GPX93_RS14940	COG5001	Diguanylate cyclase
GPX93_RS14950	COG3530	Putative quorum-sensing-regulated virulence factor
GPX93_RS14960	COG3033	Beta-eliminating lyase
GPX93_RS14965	COG0814	amino acid
GPX93_RS14970	COG0589	response to stress
GPX93_RS14980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GPX93_RS14980	COG2111	Na H antiporter
GPX93_RS15000	COG2212	antiporter activity
GPX93_RS15005	COG1320	monovalent cation:proton antiporter activity
GPX93_RS15015	COG0242	peptide deformylase activity
GPX93_RS15025	COG0579	oxidoreductase
GPX93_RS15060	COG2271	Major facilitator Superfamily
GPX93_RS15065	COG0584	glycerophosphoryl diester phosphodiesterase
GPX93_RS15075	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GPX93_RS15085	COG1609	Transcriptional regulator
GPX93_RS15090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPX93_RS15095	COG1879	ABC-type sugar transport system periplasmic component
GPX93_RS15100	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPX93_RS15105	COG1129	ABC transporter
GPX93_RS15110	COG1869	D-ribose catabolic process
GPX93_RS15130	COG3501	Rhs element vgr protein
GPX93_RS15225	COG0564	pseudouridine synthase activity
GPX93_RS15235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPX93_RS15240	COG2200	EAL domain
GPX93_RS15240	COG2771	luxR family
GPX93_RS15250	COG0673	inositol 2-dehydrogenase activity
GPX93_RS15255	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPX93_RS15290	COG1342	Belongs to the UPF0251 family
GPX93_RS15300	COG1301	dicarboxylic acid transport
GPX93_RS15325	COG2814	Major facilitator Superfamily
GPX93_RS15330	COG0583	DNA-binding transcription factor activity
GPX93_RS15335	COG5001	Diguanylate cyclase
GPX93_RS15335	COG3300	MHYT domain
GPX93_RS15340	COG0739	heme binding
GPX93_RS15350	COG0659	secondary active sulfate transmembrane transporter activity
GPX93_RS15370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPX93_RS15375	COG0581	inorganic phosphate transmembrane transporter activity
GPX93_RS15380	COG0573	inorganic phosphate transmembrane transporter activity
GPX93_RS15385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPX93_RS15415	COG1770	oligopeptidase
GPX93_RS15420	COG0513	Belongs to the DEAD box helicase family
GPX93_RS15430	COG1388	LysM domain
GPX93_RS15430	COG1376	ErfK ybiS ycfS ynhG family protein
GPX93_RS15435	COG0415	Belongs to the DNA photolyase family
GPX93_RS15445	COG3272	Protein of unknown function (DUF1722)
GPX93_RS15450	COG0813	purine-nucleoside phosphorylase activity
GPX93_RS15465	COG3706	GGDEF domain
GPX93_RS15485	COG0786	glutamate:sodium symporter activity
GPX93_RS15500	COG1999	signal sequence binding
GPX93_RS15510	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GPX93_RS15515	COG0671	phosphoesterase, PA-phosphatase related
GPX93_RS15560	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPX93_RS15565	COG0471	metal ion transport
GPX93_RS15600	COG3501	Rhs element vgr protein
GPX93_RS15610	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GPX93_RS15615	COG1640	4-alpha-glucanotransferase
GPX93_RS15620	COG0058	SHG alpha-glucan phosphorylase activity
GPX93_RS15625	COG2909	trisaccharide binding
GPX93_RS15645	COG2084	Dehydrogenase
GPX93_RS15650	COG0217	transcriptional regulatory protein
GPX93_RS15685	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPX93_RS15690	COG1444	tRNA N-acetyltransferase activity
GPX93_RS15710	COG4221	oxidoreductase activity
GPX93_RS15720	COG0745	RESPONSE REGULATOR receiver
GPX93_RS15725	COG0642	Histidine kinase
GPX93_RS15730	COG2194	sulfuric ester hydrolase activity
GPX93_RS15735	COG4608	Belongs to the ABC transporter superfamily
GPX93_RS15740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPX93_RS15745	COG0601	transmembrane transport
GPX93_RS15750	COG0747	negative chemotaxis
GPX93_RS15765	COG2198	Histidine kinase
GPX93_RS15765	COG0643	Histidine kinase
GPX93_RS15770	COG0835	chemotaxis
GPX93_RS15775	COG0835	chemotaxis
GPX93_RS15780	COG0840	transmembrane signaling receptor activity
GPX93_RS15785	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPX93_RS15790	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GPX93_RS15810	COG0745	RESPONSE REGULATOR receiver
GPX93_RS15840	COG0259	pyridoxamine-phosphate oxidase activity
GPX93_RS15850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GPX93_RS15875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPX93_RS15905	COG1982	Orn Lys Arg decarboxylase major
GPX93_RS15910	COG0531	amino acid
GPX93_RS15920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPX93_RS15925	COG1901	pseudouridine methyltransferase
GPX93_RS15935	COG4221	oxidoreductase activity
GPX93_RS15940	COG0840	transmembrane signaling receptor activity
GPX93_RS15945	COG0583	DNA-binding transcription factor activity
GPX93_RS15950	COG2910	NAD(P)H-binding
GPX93_RS15965	COG0697	spore germination
GPX93_RS15990	COG3722	fumarate hydratase activity
GPX93_RS15995	COG0246	Mannitol dehydrogenase
GPX93_RS16000	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX93_RS16000	COG2213	PTS system mannitol-specific
GPX93_RS16005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPX93_RS16010	COG4597	amino acid ABC transporter
GPX93_RS16015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX93_RS16025	COG1126	abc transporter atp-binding protein
GPX93_RS16030	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPX93_RS16040	COG0840	transmembrane signaling receptor activity
GPX93_RS16055	COG0840	transmembrane signaling receptor activity
GPX93_RS16070	COG4580	involved in the transport of maltose and maltodextrins
GPX93_RS16085	COG0363	glucosamine-6-phosphate deaminase activity
GPX93_RS16110	COG2259	Doxx family
GPX93_RS16115	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GPX93_RS16120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPX93_RS16130	COG0471	metal ion transport
GPX93_RS16140	COG4565	transcriptional regulatory protein
GPX93_RS16145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GPX93_RS16150	COG3366	ferrous iron transmembrane transporter activity
GPX93_RS16155	COG0700	Nucleoside recognition
GPX93_RS16165	COG0697	spore germination
GPX93_RS16170	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPX93_RS16175	COG1764	response to oxidative stress
GPX93_RS16180	COG1846	Transcriptional regulator
GPX93_RS16200	COG2207	Transcriptional regulator
GPX93_RS16210	COG1902	pentaerythritol trinitrate reductase activity
GPX93_RS16220	COG1132	(ABC) transporter
GPX93_RS16230	COG0513	Belongs to the DEAD box helicase family
GPX93_RS16250	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GPX93_RS16260	COG1304	FMN binding
GPX93_RS16265	COG1620	l-lactate permease
GPX93_RS16270	COG0583	DNA-binding transcription factor activity
GPX93_RS16290	COG4172	Belongs to the ABC transporter superfamily
GPX93_RS16300	COG1067	ATP-dependent peptidase activity
GPX93_RS16305	COG0840	transmembrane signaling receptor activity
GPX93_RS16315	COG2211	Major facilitator Superfamily
GPX93_RS16325	COG3123	guanosine phosphorylase activity
GPX93_RS16330	COG1741	Belongs to the pirin family
GPX93_RS16340	COG5001	Diguanylate cyclase
GPX93_RS16345	COG0583	DNA-binding transcription factor activity
GPX93_RS16380	COG3706	GGDEF domain
GPX93_RS16385	COG1846	Transcriptional regulator
GPX93_RS16390	COG0784	Response regulator, receiver
GPX93_RS16390	COG0835	chemotaxis
GPX93_RS16395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPX93_RS16400	COG2197	response regulator
GPX93_RS16405	COG0393	Putative heavy-metal-binding
GPX93_RS16420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPX93_RS16425	COG3842	ATPase activity
GPX93_RS16435	COG1175	transmembrane transport
GPX93_RS16440	COG3833	ABC-type maltose transport systems, permease component
GPX93_RS16455	COG1349	DNA-binding transcription factor activity
GPX93_RS16460	COG3706	GGDEF domain
GPX93_RS16485	COG1278	Cold shock
GPX93_RS16490	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPX93_RS16495	COG2354	Protein conserved in bacteria
GPX93_RS16500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPX93_RS16510	COG3152	Membrane
GPX93_RS16520	COG0418	dihydroorotase activity
GPX93_RS16525	COG3217	Mosc domain protein beta barrel domain protein
GPX93_RS16525	COG0633	Ferredoxin
GPX93_RS16525	COG3217	Mosc domain protein beta barrel domain protein
GPX93_RS16525	COG0633	Ferredoxin
GPX93_RS16560	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GPX93_RS16565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPX93_RS16570	COG4558	Periplasmic binding protein
GPX93_RS16575	COG0848	biopolymer transport protein
GPX93_RS16580	COG0811	peptide transport
GPX93_RS16585	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GPX93_RS16595	COG3721	Heme iron utilization protein
GPX93_RS16600	COG0748	coenzyme F420 binding
GPX93_RS16610	COG3835	regulator
GPX93_RS16615	COG2610	gluconate transmembrane transporter activity
GPX93_RS16620	COG1929	Belongs to the glycerate kinase type-1 family
GPX93_RS16645	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPX93_RS16650	COG0363	glucosamine-6-phosphate deaminase activity
GPX93_RS16655	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPX93_RS16660	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPX93_RS16665	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPX93_RS16685	COG0346	lactoylglutathione lyase activity
GPX93_RS16695	COG2873	o-acetylhomoserine
GPX93_RS16700	COG0156	8-amino-7-oxononanoate synthase activity
GPX93_RS16705	COG1063	alcohol dehydrogenase
GPX93_RS16750	COG1063	alcohol dehydrogenase
GPX93_RS16755	COG0789	Transcriptional regulator
GPX93_RS16770	COG0583	DNA-binding transcription factor activity
GPX93_RS16775	COG3048	D-serine ammonia-lyase activity
GPX93_RS16785	COG1278	Cold shock
GPX93_RS16790	COG0557	exoribonuclease II activity
GPX93_RS16795	COG1686	Belongs to the peptidase S11 family
GPX93_RS16805	COG3047	cAMP biosynthetic process
GPX93_RS16815	COG3227	Zinc metalloprotease (Elastase)
GPX93_RS16825	COG2267	carboxylic ester hydrolase activity
GPX93_RS16830	COG2067	long-chain fatty acid transport protein
GPX93_RS16840	COG0366	Alpha amylase catalytic
GPX93_RS16845	COG4989	oxidoreductase activity
GPX93_RS16860	COG1136	(ABC) transporter
GPX93_RS16865	COG0577	efflux transmembrane transporter activity
GPX93_RS16865	COG1136	(ABC) transporter
GPX93_RS16880	COG3275	phosphorelay sensor kinase activity
GPX93_RS16885	COG3279	Response regulator of the LytR AlgR family
GPX93_RS16895	COG3706	GGDEF domain
GPX93_RS16900	COG0531	amino acid
GPX93_RS16905	COG1252	NADH dehydrogenase
GPX93_RS16935	COG1765	OsmC-like protein
GPX93_RS16940	COG1253	flavin adenine dinucleotide binding
GPX93_RS16945	COG2171	N-acyltransferase activity
GPX93_RS16960	COG0583	DNA-binding transcription factor activity
GPX93_RS16965	COG2264	protein methyltransferase activity
GPX93_RS16980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPX93_RS16985	COG3186	Phenylalanine-4-hydroxylase
GPX93_RS16990	COG2154	pterin-4-alpha-carbinolamine dehydratase
GPX93_RS16995	COG0456	acetyltransferase
GPX93_RS17000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPX93_RS17010	COG0527	aspartate kinase activity
GPX93_RS17020	COG0459	protein refolding
GPX93_RS17025	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPX93_RS17030	COG2239	Acts as a magnesium transporter
GPX93_RS17040	COG1166	arginine decarboxylase activity
GPX93_RS17060	COG3397	chitin binding
GPX93_RS17065	COG3046	protein related to deoxyribodipyrimidine photolyase
GPX93_RS17075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPX93_RS17085	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GPX93_RS17090	COG0513	Belongs to the DEAD box helicase family
GPX93_RS17100	COG1368	sulfuric ester hydrolase activity
GPX93_RS17105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPX93_RS17120	COG0546	phosphoglycolate phosphatase activity
GPX93_RS17135	COG0484	heat shock protein binding
GPX93_RS17150	COG5001	Diguanylate cyclase
GPX93_RS17150	COG1716	ATPase activity
GPX93_RS17155	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPX93_RS17165	COG4181	ATPase activity
GPX93_RS17170	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GPX93_RS17230	COG4387	Mu-like prophage protein GP36
GPX93_RS17240	COG4397	Mu-like prophage major head subunit gpT
GPX93_RS17250	COG4388	Caudovirus prohead serine protease
GPX93_RS17275	COG4383	Mu-like prophage protein gp29
GPX93_RS17280	COG4373	Mu-like prophage FluMu protein gp28
GPX93_RS17290	COG0640	Transcriptional regulator
GPX93_RS17320	COG1192	Involved in chromosome partitioning
GPX93_RS17325	COG4382	Mu-like prophage protein Gp16
GPX93_RS17390	COG1984	allophanate hydrolase subunit 2
GPX93_RS17395	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GPX93_RS17400	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GPX93_RS17405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPX93_RS17410	COG0840	transmembrane signaling receptor activity
GPX93_RS17415	COG0814	amino acid
GPX93_RS17425	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GPX93_RS17430	COG0513	Belongs to the DEAD box helicase family
GPX93_RS17435	COG1309	transcriptional regulator
GPX93_RS17445	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GPX93_RS17450	COG0494	nUDIX hydrolase
GPX93_RS17460	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GPX93_RS17470	COG1126	abc transporter atp-binding protein
GPX93_RS17475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX93_RS17480	COG4215	(ABC) transporter
GPX93_RS17485	COG4160	amino acid transport
GPX93_RS17510	COG3118	belongs to the thioredoxin family
GPX93_RS17515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPX93_RS17520	COG0247	lactate metabolic process
GPX93_RS17525	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GPX93_RS17530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPX93_RS17535	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPX93_RS17570	COG2827	Endonuclease containing a URI domain
GPX93_RS17580	COG1879	ABC-type sugar transport system periplasmic component
GPX93_RS17585	COG0784	Response regulator, receiver
GPX93_RS17585	COG5002	protein histidine kinase activity
GPX93_RS17615	COG0631	protein serine/threonine phosphatase activity
GPX93_RS17625	COG0515	serine threonine protein kinase
GPX93_RS17630	COG2815	serine threonine protein kinase
GPX93_RS17630	COG0515	serine threonine protein kinase
GPX93_RS17635	COG1492	cobalamin metabolic process
GPX93_RS17640	COG0725	ABC transporter, periplasmic molybdate-binding protein
GPX93_RS17645	COG4149	molybdate abc transporter
GPX93_RS17650	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GPX93_RS17680	COG1289	transmembrane transporter activity
GPX93_RS17685	COG0210	DNA helicase
GPX93_RS17700	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPX93_RS17705	COG1335	isochorismatase
GPX93_RS17710	COG1803	Methylglyoxal synthase
GPX93_RS17715	COG1879	ABC-type sugar transport system periplasmic component
GPX93_RS17725	COG0469	pyruvate kinase activity
GPX93_RS17730	COG2271	Major facilitator Superfamily
GPX93_RS17735	COG1840	ABC-type Fe3 transport system, periplasmic component
GPX93_RS17740	COG4191	Histidine kinase
GPX93_RS17755	COG1979	alcohol dehydrogenase
GPX93_RS17765	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPX93_RS17770	COG3706	GGDEF domain
GPX93_RS17785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPX93_RS17790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPX93_RS17800	COG0183	Belongs to the thiolase family
GPX93_RS17810	COG3243	poly(R)-hydroxyalkanoic acid synthase
GPX93_RS17815	COG3842	ATPase activity
GPX93_RS17825	COG1840	ABC-type Fe3 transport system, periplasmic component
GPX93_RS17830	COG2271	Major facilitator Superfamily
GPX93_RS17835	COG3851	Histidine kinase
GPX93_RS17840	COG2197	response regulator
GPX93_RS17845	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPX93_RS17865	COG0243	molybdopterin cofactor binding
GPX93_RS17875	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPX93_RS17880	COG3850	Histidine kinase
GPX93_RS17885	COG2197	response regulator
GPX93_RS17890	COG1609	Transcriptional regulator
GPX93_RS17910	COG1760	l-serine dehydratase
GPX93_RS17915	COG3069	C4-dicarboxylate transmembrane transporter activity
GPX93_RS17920	COG0840	transmembrane signaling receptor activity
GPX93_RS17925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPX93_RS17930	COG0545	Peptidyl-prolyl cis-trans isomerase
GPX93_RS17935	COG2885	chlorophyll binding
GPX93_RS17945	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPX93_RS17950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPX93_RS17955	COG1621	beta-fructofuranosidase activity
GPX93_RS17965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX93_RS17965	COG1263	PTS System
GPX93_RS18020	COG0640	Transcriptional regulator
GPX93_RS18050	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GPX93_RS18055	COG0583	DNA-binding transcription factor activity
GPX93_RS18080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPX93_RS18110	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPX93_RS18115	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPX93_RS18120	COG2390	Transcriptional regulator
GPX93_RS18125	COG2897	thiosulfate sulfurtransferase activity
GPX93_RS18135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPX93_RS18145	COG0302	gtp cyclohydrolase
GPX93_RS18150	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPX93_RS18150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPX93_RS18155	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GPX93_RS18160	COG1970	mechanosensitive ion channel activity
GPX93_RS18165	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GPX93_RS18175	COG1011	Hydrolase
GPX93_RS18180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPX93_RS18185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPX93_RS18225	COG1943	Transposase
GPX93_RS18245	COG4166	transmembrane transport
GPX93_RS18250	COG4174	ABC transporter (Permease)
GPX93_RS18255	COG4239	(ABC) transporter, permease
GPX93_RS18260	COG4172	Belongs to the ABC transporter superfamily
GPX93_RS18265	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPX93_RS18280	COG0625	glutathione transferase activity
GPX93_RS18300	COG2050	protein possibly involved in aromatic compounds catabolism
GPX93_RS18315	COG4771	TonB-dependent receptor
GPX93_RS18315	COG1629	transport
GPX93_RS18320	COG0583	DNA-binding transcription factor activity
GPX93_RS18325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPX93_RS18325	COG0045	succinate-CoA ligase (ADP-forming) activity
GPX93_RS18325	COG1042	CoA-binding domain protein
GPX93_RS18335	COG1181	Belongs to the D-alanine--D-alanine ligase family
GPX93_RS18345	COG0023	Translation Initiation Factor
GPX93_RS18365	COG0745	RESPONSE REGULATOR receiver
GPX93_RS18375	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GPX93_RS18380	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GPX93_RS18395	COG3706	GGDEF domain
GPX93_RS18450	COG2824	Alkylphosphonate utilization operon protein PhnA
GPX93_RS18465	COG0737	Belongs to the 5'-nucleotidase family
GPX93_RS18470	COG3593	DNA synthesis involved in DNA repair
GPX93_RS18480	COG0583	DNA-binding transcription factor activity
GPX93_RS18485	COG2116	formate transmembrane transporter activity
GPX93_RS18495	COG3038	cytochrome b561
GPX93_RS18505	COG2200	EAL domain
GPX93_RS18515	COG0586	Pfam SNARE associated Golgi protein
GPX93_RS18520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPX93_RS18525	COG0745	RESPONSE REGULATOR receiver
GPX93_RS18530	COG2205	protein histidine kinase activity
GPX93_RS18535	COG0674	pyruvate-flavodoxin oxidoreductase activity
GPX93_RS18535	COG1013	pyruvate-flavodoxin oxidoreductase activity
GPX93_RS18535	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GPX93_RS18535	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GPX93_RS18540	COG3158	transport of potassium into the cell
GPX93_RS18550	COG0523	cobalamin synthesis protein
GPX93_RS18555	COG0038	chloride channel
GPX93_RS18565	COG0156	8-amino-7-oxononanoate synthase activity
GPX93_RS18570	COG2205	protein histidine kinase activity
GPX93_RS18570	COG0784	Response regulator, receiver
GPX93_RS18575	COG0419	ATPase involved in DNA repair
GPX93_RS18580	COG0420	3'-5' exonuclease activity
GPX93_RS18585	COG1609	Transcriptional regulator
GPX93_RS18590	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX93_RS18590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX93_RS18595	COG1105	Belongs to the carbohydrate kinase PfkB family
GPX93_RS18600	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX93_RS18600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX93_RS18600	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GPX93_RS18605	COG0189	ligase activity
GPX93_RS18605	COG4067	protein conserved in archaea
GPX93_RS18615	COG0602	queuosine metabolic process
GPX93_RS18620	COG1328	CTP reductase activity